ORF_ID e_value Gene_name EC_number CAZy COGs Description
NLHAPFBO_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NLHAPFBO_00002 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NLHAPFBO_00003 1.1e-29 yyzM S Protein conserved in bacteria
NLHAPFBO_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NLHAPFBO_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NLHAPFBO_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NLHAPFBO_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NLHAPFBO_00008 2.7e-61 divIC D Septum formation initiator
NLHAPFBO_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
NLHAPFBO_00011 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NLHAPFBO_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NLHAPFBO_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NLHAPFBO_00014 1.3e-137 L Transposase
NLHAPFBO_00015 1.1e-92 L Transposase
NLHAPFBO_00016 1.6e-55 L transposition
NLHAPFBO_00017 1.9e-86 L Integrase core domain protein
NLHAPFBO_00030 5.3e-11
NLHAPFBO_00036 5.5e-139 mreC M Involved in formation and maintenance of cell shape
NLHAPFBO_00037 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NLHAPFBO_00038 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
NLHAPFBO_00039 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLHAPFBO_00040 2.9e-218 araT 2.6.1.1 E Aminotransferase
NLHAPFBO_00041 2.6e-143 recO L Involved in DNA repair and RecF pathway recombination
NLHAPFBO_00042 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NLHAPFBO_00043 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLHAPFBO_00044 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NLHAPFBO_00045 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLHAPFBO_00046 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NLHAPFBO_00047 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NLHAPFBO_00048 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NLHAPFBO_00049 1.2e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NLHAPFBO_00050 4.8e-76 L transposase activity
NLHAPFBO_00051 1.4e-48 L transposition
NLHAPFBO_00052 1.4e-33 L Integrase core domain protein
NLHAPFBO_00053 2.3e-161 S CHAP domain
NLHAPFBO_00054 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
NLHAPFBO_00055 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NLHAPFBO_00056 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NLHAPFBO_00057 9.2e-141 1.1.1.169 H Ketopantoate reductase
NLHAPFBO_00058 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NLHAPFBO_00059 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NLHAPFBO_00060 2.6e-09 L Transposase
NLHAPFBO_00061 8.2e-70 argR K Regulates arginine biosynthesis genes
NLHAPFBO_00062 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NLHAPFBO_00063 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NLHAPFBO_00064 7e-34 S Protein of unknown function (DUF3021)
NLHAPFBO_00065 1.2e-61 KT phosphorelay signal transduction system
NLHAPFBO_00067 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NLHAPFBO_00069 1.2e-165 L integrase core domain
NLHAPFBO_00070 4.7e-117 L Transposase
NLHAPFBO_00071 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NLHAPFBO_00072 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
NLHAPFBO_00073 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
NLHAPFBO_00074 2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NLHAPFBO_00075 1.1e-65 spxA_2 1.20.4.1 P Belongs to the ArsC family
NLHAPFBO_00081 2.6e-10
NLHAPFBO_00084 1.9e-07
NLHAPFBO_00089 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLHAPFBO_00090 5.7e-222 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NLHAPFBO_00091 5.5e-36 XK27_02060 S Transglycosylase associated protein
NLHAPFBO_00092 1.8e-26 badR K DNA-binding transcription factor activity
NLHAPFBO_00093 1.7e-96 S reductase
NLHAPFBO_00094 1e-87 L Integrase core domain protein
NLHAPFBO_00095 3.2e-40 L transposition
NLHAPFBO_00096 7.3e-22 yocD 3.4.17.13 V carboxypeptidase activity
NLHAPFBO_00097 1.9e-86 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NLHAPFBO_00100 6.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NLHAPFBO_00101 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NLHAPFBO_00102 1.1e-83 S Putative small multi-drug export protein
NLHAPFBO_00103 2.4e-75 ctsR K Belongs to the CtsR family
NLHAPFBO_00104 0.0 clpC O Belongs to the ClpA ClpB family
NLHAPFBO_00105 8.1e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLHAPFBO_00106 8.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLHAPFBO_00107 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLHAPFBO_00108 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NLHAPFBO_00109 4.5e-143 S SseB protein N-terminal domain
NLHAPFBO_00110 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
NLHAPFBO_00111 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLHAPFBO_00112 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NLHAPFBO_00115 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLHAPFBO_00116 3.5e-91 yacP S RNA-binding protein containing a PIN domain
NLHAPFBO_00117 3.4e-155 degV S DegV family
NLHAPFBO_00119 2.3e-31 K helix-turn-helix
NLHAPFBO_00120 1.6e-94 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLHAPFBO_00121 3.6e-57 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLHAPFBO_00122 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NLHAPFBO_00123 1.1e-63 rpsI J Belongs to the universal ribosomal protein uS9 family
NLHAPFBO_00124 1.5e-35 K sequence-specific DNA binding
NLHAPFBO_00126 0.0 S Lantibiotic dehydratase, C terminus
NLHAPFBO_00127 2.4e-231 spaC2 V Lanthionine synthetase C family protein
NLHAPFBO_00128 2.5e-183 EGP Major facilitator Superfamily
NLHAPFBO_00129 5.9e-24 3.6.4.12
NLHAPFBO_00130 6.5e-90 3.6.4.12 K Divergent AAA domain protein
NLHAPFBO_00131 9.3e-184 L Phage integrase family
NLHAPFBO_00132 1.7e-22
NLHAPFBO_00133 1.3e-154
NLHAPFBO_00135 1.3e-134 D ftsk spoiiie
NLHAPFBO_00136 5.3e-18 D FtsK/SpoIIIE family
NLHAPFBO_00139 9.7e-227 sthIM 2.1.1.72 L DNA methylase
NLHAPFBO_00140 0.0 res_1 3.1.21.5 S Type III restriction
NLHAPFBO_00142 2.2e-224 int L Belongs to the 'phage' integrase family
NLHAPFBO_00143 1.8e-38 S Helix-turn-helix domain
NLHAPFBO_00144 4.9e-173
NLHAPFBO_00146 3.4e-75 isp2 S pathogenesis
NLHAPFBO_00147 5.7e-91 tnp L Transposase
NLHAPFBO_00148 3.3e-225 capA M Bacterial capsule synthesis protein
NLHAPFBO_00149 3.6e-39 gcvR T UPF0237 protein
NLHAPFBO_00150 1.9e-242 XK27_08635 S UPF0210 protein
NLHAPFBO_00151 2.2e-38 ais G alpha-ribazole phosphatase activity
NLHAPFBO_00152 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NLHAPFBO_00153 1.3e-102 acmA 3.2.1.17 NU amidase activity
NLHAPFBO_00154 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NLHAPFBO_00155 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NLHAPFBO_00156 9.8e-298 dnaK O Heat shock 70 kDa protein
NLHAPFBO_00157 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NLHAPFBO_00158 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NLHAPFBO_00159 4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NLHAPFBO_00160 1.7e-60 hmpT S membrane
NLHAPFBO_00161 2.6e-12
NLHAPFBO_00174 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NLHAPFBO_00175 2.5e-169 L Transposase
NLHAPFBO_00176 9.9e-19 S Domain of unknown function (DUF4649)
NLHAPFBO_00177 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NLHAPFBO_00178 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NLHAPFBO_00179 6.5e-87
NLHAPFBO_00180 1.6e-77 sigH K DNA-templated transcription, initiation
NLHAPFBO_00181 4.6e-149 ykuT M mechanosensitive ion channel
NLHAPFBO_00182 1.9e-218 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NLHAPFBO_00183 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NLHAPFBO_00184 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NLHAPFBO_00185 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
NLHAPFBO_00186 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
NLHAPFBO_00187 2e-177 prmA J Ribosomal protein L11 methyltransferase
NLHAPFBO_00188 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NLHAPFBO_00189 1.4e-42 F nucleotide catabolic process
NLHAPFBO_00190 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NLHAPFBO_00191 6.3e-186 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NLHAPFBO_00192 3.8e-81 nrdI F Belongs to the NrdI family
NLHAPFBO_00193 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLHAPFBO_00194 8.7e-27 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLHAPFBO_00195 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NLHAPFBO_00196 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NLHAPFBO_00197 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NLHAPFBO_00198 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NLHAPFBO_00199 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NLHAPFBO_00200 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NLHAPFBO_00201 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NLHAPFBO_00202 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NLHAPFBO_00203 6.5e-202 yhjX P Major Facilitator
NLHAPFBO_00204 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NLHAPFBO_00205 5e-94 V VanZ like family
NLHAPFBO_00206 1e-123 glnQ E abc transporter atp-binding protein
NLHAPFBO_00207 5.8e-275 glnP P ABC transporter
NLHAPFBO_00208 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NLHAPFBO_00209 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NLHAPFBO_00210 5.5e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
NLHAPFBO_00211 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NLHAPFBO_00212 6.3e-235 sufD O assembly protein SufD
NLHAPFBO_00213 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NLHAPFBO_00214 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
NLHAPFBO_00215 2.2e-273 sufB O assembly protein SufB
NLHAPFBO_00216 7e-10 oppA E ABC transporter substrate-binding protein
NLHAPFBO_00217 2e-138 oppA E ABC transporter substrate-binding protein
NLHAPFBO_00218 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLHAPFBO_00219 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLHAPFBO_00220 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLHAPFBO_00221 2.5e-09 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLHAPFBO_00222 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLHAPFBO_00223 3e-27 oppD P Belongs to the ABC transporter superfamily
NLHAPFBO_00224 2.5e-32 oppD P Belongs to the ABC transporter superfamily
NLHAPFBO_00225 1.2e-62 oppD P Belongs to the ABC transporter superfamily
NLHAPFBO_00226 2.7e-41 oppD P Belongs to the ABC transporter superfamily
NLHAPFBO_00227 7.5e-62 oppF P Belongs to the ABC transporter superfamily
NLHAPFBO_00228 3.4e-62 oppF P Belongs to the ABC transporter superfamily
NLHAPFBO_00229 6.4e-23
NLHAPFBO_00230 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NLHAPFBO_00231 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLHAPFBO_00232 9.4e-223 EGP Major facilitator Superfamily
NLHAPFBO_00233 3.1e-72 adcR K transcriptional
NLHAPFBO_00234 8.3e-136 adcC P ABC transporter, ATP-binding protein
NLHAPFBO_00235 1.6e-127 adcB P ABC transporter (Permease
NLHAPFBO_00236 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NLHAPFBO_00237 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
NLHAPFBO_00238 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
NLHAPFBO_00239 4.8e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NLHAPFBO_00240 6.6e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
NLHAPFBO_00241 1.1e-256 pgi 5.3.1.9 G Belongs to the GPI family
NLHAPFBO_00242 1.9e-127 yeeN K transcriptional regulatory protein
NLHAPFBO_00243 9.8e-50 yajC U protein transport
NLHAPFBO_00244 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLHAPFBO_00245 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
NLHAPFBO_00246 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NLHAPFBO_00247 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NLHAPFBO_00248 0.0 WQ51_06230 S ABC transporter substrate binding protein
NLHAPFBO_00249 5.2e-142 cmpC S abc transporter atp-binding protein
NLHAPFBO_00250 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NLHAPFBO_00251 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NLHAPFBO_00252 4.4e-37 L Transposase
NLHAPFBO_00253 3.2e-10 L transposase activity
NLHAPFBO_00254 1.7e-51 L transposition
NLHAPFBO_00255 1.4e-33 L Integrase core domain protein
NLHAPFBO_00257 1.7e-54 S TM2 domain
NLHAPFBO_00258 1.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLHAPFBO_00259 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLHAPFBO_00260 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NLHAPFBO_00261 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
NLHAPFBO_00262 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
NLHAPFBO_00263 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
NLHAPFBO_00264 6e-55 cof Q phosphatase activity
NLHAPFBO_00265 6.2e-35 cof Q phosphatase activity
NLHAPFBO_00266 1.6e-137 glcR K transcriptional regulator (DeoR family)
NLHAPFBO_00267 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLHAPFBO_00269 3.8e-40 K transcriptional
NLHAPFBO_00271 2.6e-76 S thiolester hydrolase activity
NLHAPFBO_00272 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
NLHAPFBO_00273 1.3e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NLHAPFBO_00274 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NLHAPFBO_00275 1.9e-77 yhaI L Membrane
NLHAPFBO_00276 5.1e-259 pepC 3.4.22.40 E aminopeptidase
NLHAPFBO_00277 3.6e-249 L Transposase
NLHAPFBO_00278 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLHAPFBO_00279 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NLHAPFBO_00280 8.9e-95 ypsA S Belongs to the UPF0398 family
NLHAPFBO_00281 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NLHAPFBO_00282 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NLHAPFBO_00283 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NLHAPFBO_00284 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
NLHAPFBO_00285 3.3e-23
NLHAPFBO_00286 5.7e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NLHAPFBO_00287 2.1e-82 XK27_09675 K -acetyltransferase
NLHAPFBO_00288 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NLHAPFBO_00289 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLHAPFBO_00290 5.2e-59 L Integrase core domain protein
NLHAPFBO_00291 8.5e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLHAPFBO_00292 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NLHAPFBO_00293 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLHAPFBO_00294 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
NLHAPFBO_00295 8.8e-98 ybhL S Belongs to the BI1 family
NLHAPFBO_00298 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NLHAPFBO_00299 3.7e-91 K transcriptional regulator
NLHAPFBO_00300 7.6e-36 yneF S UPF0154 protein
NLHAPFBO_00301 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NLHAPFBO_00302 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NLHAPFBO_00303 3.5e-99 XK27_09740 S Phosphoesterase
NLHAPFBO_00304 7.8e-85 ykuL S CBS domain
NLHAPFBO_00305 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NLHAPFBO_00306 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NLHAPFBO_00307 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NLHAPFBO_00308 1.3e-139 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLHAPFBO_00309 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NLHAPFBO_00310 1.2e-258 trkH P Cation transport protein
NLHAPFBO_00311 1.3e-246 trkA P Potassium transporter peripheral membrane component
NLHAPFBO_00312 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NLHAPFBO_00313 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NLHAPFBO_00314 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
NLHAPFBO_00315 5.6e-161 K sequence-specific DNA binding
NLHAPFBO_00316 1.2e-32 V protein secretion by the type I secretion system
NLHAPFBO_00317 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NLHAPFBO_00318 1.2e-54 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NLHAPFBO_00319 1.8e-34 V protein secretion by the type I secretion system
NLHAPFBO_00320 2.3e-129 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NLHAPFBO_00321 1.8e-50 yhaI L Membrane
NLHAPFBO_00322 2.1e-105 S Domain of unknown function (DUF4173)
NLHAPFBO_00323 6.8e-95 ureI S AmiS/UreI family transporter
NLHAPFBO_00324 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NLHAPFBO_00325 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NLHAPFBO_00326 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NLHAPFBO_00327 6.6e-78 ureE O enzyme active site formation
NLHAPFBO_00328 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NLHAPFBO_00329 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NLHAPFBO_00330 3.4e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NLHAPFBO_00331 4.3e-175 cbiM P PDGLE domain
NLHAPFBO_00332 1.1e-136 P cobalt transport protein
NLHAPFBO_00333 1.6e-131 cbiO P ABC transporter
NLHAPFBO_00334 5.3e-153 ET amino acid transport
NLHAPFBO_00335 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLHAPFBO_00336 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
NLHAPFBO_00337 3.8e-205 EGP Transmembrane secretion effector
NLHAPFBO_00338 1.8e-153 ET amino acid transport
NLHAPFBO_00339 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
NLHAPFBO_00340 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NLHAPFBO_00341 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
NLHAPFBO_00342 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
NLHAPFBO_00343 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLHAPFBO_00344 5.2e-98 metI P ABC transporter (Permease
NLHAPFBO_00345 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NLHAPFBO_00346 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
NLHAPFBO_00347 8e-94 S UPF0397 protein
NLHAPFBO_00348 0.0 ykoD P abc transporter atp-binding protein
NLHAPFBO_00349 1.2e-146 cbiQ P cobalt transport
NLHAPFBO_00350 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NLHAPFBO_00351 6.9e-11 ulaG S L-ascorbate 6-phosphate lactonase
NLHAPFBO_00352 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
NLHAPFBO_00353 2.7e-244 P COG0168 Trk-type K transport systems, membrane components
NLHAPFBO_00354 1.2e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
NLHAPFBO_00355 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
NLHAPFBO_00356 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLHAPFBO_00357 2.8e-282 T PhoQ Sensor
NLHAPFBO_00358 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NLHAPFBO_00359 6.5e-218 dnaB L Replication initiation and membrane attachment
NLHAPFBO_00360 4.4e-166 dnaI L Primosomal protein DnaI
NLHAPFBO_00361 2.2e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NLHAPFBO_00363 1.2e-34
NLHAPFBO_00364 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
NLHAPFBO_00365 7.9e-28 L Integrase core domain protein
NLHAPFBO_00366 3.4e-50 L transposition
NLHAPFBO_00367 5.7e-23 L Transposase
NLHAPFBO_00368 7.8e-28 L transposase activity
NLHAPFBO_00369 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NLHAPFBO_00370 4.2e-62 manO S protein conserved in bacteria
NLHAPFBO_00371 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
NLHAPFBO_00372 2.3e-116 manM G pts system
NLHAPFBO_00373 1.1e-181 manL 2.7.1.191 G pts system
NLHAPFBO_00374 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
NLHAPFBO_00375 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NLHAPFBO_00376 2.5e-248 pbuO S permease
NLHAPFBO_00377 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
NLHAPFBO_00378 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
NLHAPFBO_00379 2.5e-220 brpA K Transcriptional
NLHAPFBO_00380 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
NLHAPFBO_00381 3.1e-212 nusA K Participates in both transcription termination and antitermination
NLHAPFBO_00382 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
NLHAPFBO_00383 2e-46 ylxQ J ribosomal protein
NLHAPFBO_00384 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NLHAPFBO_00385 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NLHAPFBO_00386 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
NLHAPFBO_00387 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
NLHAPFBO_00388 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NLHAPFBO_00389 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NLHAPFBO_00390 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NLHAPFBO_00391 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
NLHAPFBO_00392 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
NLHAPFBO_00393 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
NLHAPFBO_00394 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NLHAPFBO_00396 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NLHAPFBO_00397 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NLHAPFBO_00398 1.2e-74 ylbF S Belongs to the UPF0342 family
NLHAPFBO_00399 7.1e-46 ylbG S UPF0298 protein
NLHAPFBO_00400 1.3e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NLHAPFBO_00401 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
NLHAPFBO_00402 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
NLHAPFBO_00403 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NLHAPFBO_00404 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NLHAPFBO_00405 6.8e-69 acuB S IMP dehydrogenase activity
NLHAPFBO_00406 8.9e-41 acuB S IMP dehydrogenase activity
NLHAPFBO_00407 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NLHAPFBO_00408 1.1e-110 yvyE 3.4.13.9 S YigZ family
NLHAPFBO_00409 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NLHAPFBO_00410 1.7e-122 comFC S Competence protein
NLHAPFBO_00411 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NLHAPFBO_00412 1.6e-12
NLHAPFBO_00420 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
NLHAPFBO_00421 6.4e-108 S Domain of unknown function (DUF1803)
NLHAPFBO_00422 1.3e-101 ygaC J Belongs to the UPF0374 family
NLHAPFBO_00423 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
NLHAPFBO_00424 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLHAPFBO_00425 2.3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
NLHAPFBO_00426 2.6e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
NLHAPFBO_00427 7.3e-115 S Haloacid dehalogenase-like hydrolase
NLHAPFBO_00428 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
NLHAPFBO_00429 4e-72 marR K Transcriptional regulator, MarR family
NLHAPFBO_00430 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLHAPFBO_00431 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLHAPFBO_00432 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
NLHAPFBO_00433 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NLHAPFBO_00434 1.6e-126 IQ reductase
NLHAPFBO_00435 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NLHAPFBO_00436 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NLHAPFBO_00437 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NLHAPFBO_00438 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NLHAPFBO_00439 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NLHAPFBO_00440 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NLHAPFBO_00441 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NLHAPFBO_00442 1.1e-65 tnp L Transposase
NLHAPFBO_00443 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NLHAPFBO_00444 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
NLHAPFBO_00445 4.7e-27 L Transposase and inactivated derivatives, TnpA family
NLHAPFBO_00446 1.1e-65 tnp L Transposase
NLHAPFBO_00448 2.7e-82 S Protein of unknown function (DUF3114)
NLHAPFBO_00449 1.1e-176 S Protein of unknown function (DUF3114)
NLHAPFBO_00450 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
NLHAPFBO_00451 7.7e-198 V (ABC) transporter
NLHAPFBO_00452 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
NLHAPFBO_00453 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
NLHAPFBO_00454 1.1e-113 K sequence-specific DNA binding
NLHAPFBO_00455 8.4e-155 L COG2801 Transposase and inactivated derivatives
NLHAPFBO_00456 6.6e-38 L transposase activity
NLHAPFBO_00457 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
NLHAPFBO_00458 8.9e-84 L Transposase
NLHAPFBO_00459 5.5e-122 fruR K transcriptional
NLHAPFBO_00460 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NLHAPFBO_00461 0.0 fruA 2.7.1.202 G phosphotransferase system
NLHAPFBO_00462 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLHAPFBO_00463 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NLHAPFBO_00465 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NLHAPFBO_00466 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLHAPFBO_00467 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NLHAPFBO_00468 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NLHAPFBO_00469 6.4e-29 2.3.1.128 K acetyltransferase
NLHAPFBO_00470 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NLHAPFBO_00471 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NLHAPFBO_00472 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLHAPFBO_00473 2.6e-64 WQ51_03320 S cog cog4835
NLHAPFBO_00474 9.8e-91 XK27_08360 S EDD domain protein, DegV family
NLHAPFBO_00475 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NLHAPFBO_00476 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NLHAPFBO_00477 0.0 yfmR S abc transporter atp-binding protein
NLHAPFBO_00478 7.2e-25 U response to pH
NLHAPFBO_00479 6.5e-77 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
NLHAPFBO_00480 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
NLHAPFBO_00481 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NLHAPFBO_00482 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NLHAPFBO_00483 1.9e-77 K DNA-binding transcription factor activity
NLHAPFBO_00484 0.0 lmrA1 V abc transporter atp-binding protein
NLHAPFBO_00485 0.0 lmrA2 V abc transporter atp-binding protein
NLHAPFBO_00486 1.4e-45 K Acetyltransferase (GNAT) family
NLHAPFBO_00487 1.3e-120 sptS 2.7.13.3 T Histidine kinase
NLHAPFBO_00488 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NLHAPFBO_00489 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NLHAPFBO_00490 1.7e-159 cvfB S Protein conserved in bacteria
NLHAPFBO_00491 7.4e-35 yozE S Belongs to the UPF0346 family
NLHAPFBO_00492 1.5e-123 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
NLHAPFBO_00493 8.9e-61 rlpA M LysM domain protein
NLHAPFBO_00494 1e-190 phoH T phosphate starvation-inducible protein PhoH
NLHAPFBO_00498 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLHAPFBO_00499 1.8e-164 K transcriptional regulator (lysR family)
NLHAPFBO_00500 1.4e-186 coiA 3.6.4.12 S Competence protein
NLHAPFBO_00501 0.0 pepF E oligoendopeptidase F
NLHAPFBO_00502 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
NLHAPFBO_00503 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
NLHAPFBO_00504 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLHAPFBO_00505 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NLHAPFBO_00506 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NLHAPFBO_00507 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
NLHAPFBO_00508 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NLHAPFBO_00509 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NLHAPFBO_00510 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NLHAPFBO_00511 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NLHAPFBO_00512 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NLHAPFBO_00513 1.4e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NLHAPFBO_00514 2.2e-130 yxkH G deacetylase
NLHAPFBO_00515 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NLHAPFBO_00516 6.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NLHAPFBO_00517 1.4e-151 rarD S Transporter
NLHAPFBO_00518 2.9e-15 T peptidase
NLHAPFBO_00519 8.9e-14 coiA 3.6.4.12 S Competence protein
NLHAPFBO_00520 8e-51 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NLHAPFBO_00521 5.9e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLHAPFBO_00522 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NLHAPFBO_00523 1.1e-250 L Transposase
NLHAPFBO_00524 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLHAPFBO_00525 2.4e-114 atpB C it plays a direct role in the translocation of protons across the membrane
NLHAPFBO_00526 3.3e-78 atpF C ATP synthase F(0) sector subunit b
NLHAPFBO_00527 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLHAPFBO_00528 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NLHAPFBO_00529 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NLHAPFBO_00530 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NLHAPFBO_00531 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NLHAPFBO_00532 2.8e-230 ftsW D Belongs to the SEDS family
NLHAPFBO_00533 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NLHAPFBO_00534 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NLHAPFBO_00535 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NLHAPFBO_00536 6.4e-162 holB 2.7.7.7 L dna polymerase iii
NLHAPFBO_00537 1.2e-135 yaaT S stage 0 sporulation protein
NLHAPFBO_00538 9.5e-55 yabA L Involved in initiation control of chromosome replication
NLHAPFBO_00539 4.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NLHAPFBO_00540 2.9e-232 amt P Ammonium Transporter
NLHAPFBO_00541 1.2e-52 glnB K Belongs to the P(II) protein family
NLHAPFBO_00542 9.2e-105 mur1 NU mannosyl-glycoprotein
NLHAPFBO_00543 2.9e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
NLHAPFBO_00544 1.5e-114 nptA P COG1283 Na phosphate symporter
NLHAPFBO_00545 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NLHAPFBO_00546 7.4e-55
NLHAPFBO_00547 4.4e-26
NLHAPFBO_00548 1.2e-61
NLHAPFBO_00549 1.7e-32 S membrane
NLHAPFBO_00550 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NLHAPFBO_00551 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NLHAPFBO_00552 4.5e-39 ynzC S UPF0291 protein
NLHAPFBO_00553 5.1e-254 cycA E permease
NLHAPFBO_00554 4.1e-09 uvrX 2.7.7.7 L impB/mucB/samB family
NLHAPFBO_00555 7.4e-25 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NLHAPFBO_00556 7e-22 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NLHAPFBO_00557 3.3e-152 pts33BCA G pts system
NLHAPFBO_00558 6.6e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLHAPFBO_00564 1.4e-167 fhuR K transcriptional regulator (lysR family)
NLHAPFBO_00565 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NLHAPFBO_00566 2.9e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLHAPFBO_00567 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NLHAPFBO_00568 3.7e-227 pyrP F uracil Permease
NLHAPFBO_00569 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NLHAPFBO_00570 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
NLHAPFBO_00571 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
NLHAPFBO_00572 5.1e-131 2.1.1.223 S Putative SAM-dependent methyltransferase
NLHAPFBO_00573 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLHAPFBO_00574 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLHAPFBO_00575 1.7e-59 V permease protein
NLHAPFBO_00576 4.6e-43 V efflux transmembrane transporter activity
NLHAPFBO_00577 7.2e-24 ytrF V efflux transmembrane transporter activity
NLHAPFBO_00578 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NLHAPFBO_00579 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NLHAPFBO_00581 0.0 mdlB V abc transporter atp-binding protein
NLHAPFBO_00582 0.0 lmrA V abc transporter atp-binding protein
NLHAPFBO_00583 1.3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NLHAPFBO_00584 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NLHAPFBO_00585 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NLHAPFBO_00586 2.5e-132 rr02 KT response regulator
NLHAPFBO_00587 2.5e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NLHAPFBO_00588 2.8e-168 V ABC transporter
NLHAPFBO_00589 5.4e-122 sagI S ABC-2 type transporter
NLHAPFBO_00590 6.9e-197 yceA S Belongs to the UPF0176 family
NLHAPFBO_00591 8e-28 XK27_00085 K Transcriptional
NLHAPFBO_00592 1.9e-22
NLHAPFBO_00593 6.5e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
NLHAPFBO_00594 1.8e-111 S VIT family
NLHAPFBO_00595 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLHAPFBO_00596 7e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NLHAPFBO_00597 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
NLHAPFBO_00598 1.3e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NLHAPFBO_00599 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLHAPFBO_00600 8.8e-104 GBS0088 J protein conserved in bacteria
NLHAPFBO_00601 7.9e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NLHAPFBO_00602 1.4e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NLHAPFBO_00603 1e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
NLHAPFBO_00604 2.4e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NLHAPFBO_00605 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NLHAPFBO_00606 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
NLHAPFBO_00607 2.5e-21
NLHAPFBO_00608 1.7e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NLHAPFBO_00610 3e-29 U protein secretion
NLHAPFBO_00611 4.2e-68 U protein secretion
NLHAPFBO_00612 4.4e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
NLHAPFBO_00613 1.2e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NLHAPFBO_00614 5.5e-49 XK27_13030
NLHAPFBO_00615 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NLHAPFBO_00616 2.3e-57 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NLHAPFBO_00617 1.6e-70 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NLHAPFBO_00618 1.1e-161 S Protein of unknown function (DUF3114)
NLHAPFBO_00619 1.6e-22 S Protein of unknown function (DUF3114)
NLHAPFBO_00620 1.1e-116 yqfA K protein, Hemolysin III
NLHAPFBO_00621 1e-25 K hmm pf08876
NLHAPFBO_00622 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NLHAPFBO_00623 1.7e-218 mvaS 2.3.3.10 I synthase
NLHAPFBO_00624 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NLHAPFBO_00625 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NLHAPFBO_00626 9.7e-22
NLHAPFBO_00627 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NLHAPFBO_00628 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NLHAPFBO_00629 1.5e-250 mmuP E amino acid
NLHAPFBO_00630 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
NLHAPFBO_00631 1.4e-29 S Domain of unknown function (DUF1912)
NLHAPFBO_00632 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
NLHAPFBO_00633 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NLHAPFBO_00634 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLHAPFBO_00635 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLHAPFBO_00636 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
NLHAPFBO_00637 4.8e-16 S Protein of unknown function (DUF2969)
NLHAPFBO_00640 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
NLHAPFBO_00643 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
NLHAPFBO_00644 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
NLHAPFBO_00645 3.7e-70 M Pfam SNARE associated Golgi protein
NLHAPFBO_00646 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
NLHAPFBO_00647 1.2e-65 S oxidoreductase
NLHAPFBO_00648 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
NLHAPFBO_00649 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NLHAPFBO_00650 0.0 clpE O Belongs to the ClpA ClpB family
NLHAPFBO_00651 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NLHAPFBO_00652 1.3e-34 ykuJ S protein conserved in bacteria
NLHAPFBO_00653 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
NLHAPFBO_00654 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLHAPFBO_00655 3.1e-78 feoA P FeoA domain protein
NLHAPFBO_00656 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NLHAPFBO_00658 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NLHAPFBO_00659 2.2e-45 K sequence-specific DNA binding
NLHAPFBO_00660 1.5e-35 yugF I carboxylic ester hydrolase activity
NLHAPFBO_00661 7.5e-23 I Alpha/beta hydrolase family
NLHAPFBO_00662 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NLHAPFBO_00663 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NLHAPFBO_00664 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
NLHAPFBO_00665 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NLHAPFBO_00666 5.8e-64 licT K transcriptional antiterminator
NLHAPFBO_00667 6.8e-53 licT K transcriptional antiterminator
NLHAPFBO_00668 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NLHAPFBO_00669 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NLHAPFBO_00670 8.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NLHAPFBO_00671 7.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NLHAPFBO_00672 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NLHAPFBO_00673 2.5e-220 mdtG EGP Major facilitator Superfamily
NLHAPFBO_00674 2e-33 secG U Preprotein translocase subunit SecG
NLHAPFBO_00675 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NLHAPFBO_00676 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NLHAPFBO_00677 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLHAPFBO_00678 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
NLHAPFBO_00679 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
NLHAPFBO_00680 4.4e-183 ccpA K Catabolite control protein A
NLHAPFBO_00681 2.8e-28 yyaQ S YjbR
NLHAPFBO_00682 6.6e-101 yyaQ V Protein conserved in bacteria
NLHAPFBO_00683 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NLHAPFBO_00684 1e-78 yueI S Protein of unknown function (DUF1694)
NLHAPFBO_00685 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NLHAPFBO_00686 2e-25 WQ51_00785
NLHAPFBO_00687 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NLHAPFBO_00688 2e-219 ywbD 2.1.1.191 J Methyltransferase
NLHAPFBO_00689 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NLHAPFBO_00690 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLHAPFBO_00691 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NLHAPFBO_00692 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NLHAPFBO_00693 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NLHAPFBO_00694 3.2e-53 yheA S Belongs to the UPF0342 family
NLHAPFBO_00695 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NLHAPFBO_00696 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NLHAPFBO_00697 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NLHAPFBO_00698 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
NLHAPFBO_00699 6.4e-252 msrR K Transcriptional regulator
NLHAPFBO_00700 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
NLHAPFBO_00701 2.4e-203 I acyl-CoA dehydrogenase
NLHAPFBO_00702 4.5e-97 mip S hydroperoxide reductase activity
NLHAPFBO_00703 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLHAPFBO_00704 3.6e-106
NLHAPFBO_00705 1e-31 K Cro/C1-type HTH DNA-binding domain
NLHAPFBO_00706 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
NLHAPFBO_00707 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
NLHAPFBO_00708 5.8e-93
NLHAPFBO_00709 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NLHAPFBO_00710 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLHAPFBO_00711 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLHAPFBO_00712 6.1e-191 S CRISPR-associated protein Csn2 subfamily St
NLHAPFBO_00713 2.3e-145 ycgQ S TIGR03943 family
NLHAPFBO_00714 1.9e-156 XK27_03015 S permease
NLHAPFBO_00716 0.0 yhgF K Transcriptional accessory protein
NLHAPFBO_00717 9.9e-42 pspC KT PspC domain
NLHAPFBO_00718 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NLHAPFBO_00719 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NLHAPFBO_00721 5.5e-69 ytxH S General stress protein
NLHAPFBO_00723 2e-177 yegQ O Peptidase U32
NLHAPFBO_00724 3.4e-252 yegQ O Peptidase U32
NLHAPFBO_00725 8.1e-46 S CHY zinc finger
NLHAPFBO_00726 8.4e-88 bioY S biotin synthase
NLHAPFBO_00728 1.1e-33 XK27_12190 S protein conserved in bacteria
NLHAPFBO_00729 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
NLHAPFBO_00730 4.8e-11
NLHAPFBO_00731 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
NLHAPFBO_00732 1.2e-224 mutH L DNA mismatch repair enzyme MutH
NLHAPFBO_00733 5.2e-29 S SIR2-like domain
NLHAPFBO_00734 1.2e-33 S SIR2-like domain
NLHAPFBO_00735 1.9e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NLHAPFBO_00736 1.5e-154 M LysM domain
NLHAPFBO_00737 5.9e-16
NLHAPFBO_00738 9.8e-174 S hydrolase
NLHAPFBO_00739 5.1e-116 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
NLHAPFBO_00740 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NLHAPFBO_00741 2.2e-144 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
NLHAPFBO_00742 2.1e-27 P Hemerythrin HHE cation binding domain protein
NLHAPFBO_00743 1.4e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NLHAPFBO_00744 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
NLHAPFBO_00745 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
NLHAPFBO_00746 8.3e-76 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NLHAPFBO_00747 1.4e-44 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NLHAPFBO_00748 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
NLHAPFBO_00749 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
NLHAPFBO_00750 2.3e-85 3.1.21.3 V type I restriction modification DNA specificity domain
NLHAPFBO_00752 2.5e-44
NLHAPFBO_00753 3e-38
NLHAPFBO_00754 8.8e-157 spd F DNA RNA non-specific endonuclease
NLHAPFBO_00755 1.5e-92 lemA S LemA family
NLHAPFBO_00756 1.8e-135 htpX O Belongs to the peptidase M48B family
NLHAPFBO_00757 5.1e-73 S Psort location CytoplasmicMembrane, score
NLHAPFBO_00758 6.2e-56 S Domain of unknown function (DUF4430)
NLHAPFBO_00759 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NLHAPFBO_00760 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
NLHAPFBO_00761 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
NLHAPFBO_00762 1.4e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
NLHAPFBO_00763 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NLHAPFBO_00764 1.6e-91 dps P Belongs to the Dps family
NLHAPFBO_00765 1.1e-80 perR P Belongs to the Fur family
NLHAPFBO_00766 8.4e-28 yqgQ S protein conserved in bacteria
NLHAPFBO_00767 1.6e-177 glk 2.7.1.2 G Glucokinase
NLHAPFBO_00768 0.0 typA T GTP-binding protein TypA
NLHAPFBO_00770 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NLHAPFBO_00771 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLHAPFBO_00772 6.9e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NLHAPFBO_00773 1.1e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NLHAPFBO_00774 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NLHAPFBO_00775 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NLHAPFBO_00776 2e-95 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NLHAPFBO_00777 8.8e-35 yggT D integral membrane protein
NLHAPFBO_00778 4.7e-143 ylmH T S4 RNA-binding domain
NLHAPFBO_00779 3.3e-134 divIVA D Cell division protein DivIVA
NLHAPFBO_00780 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NLHAPFBO_00781 3.2e-45 L Transposase
NLHAPFBO_00783 8.8e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
NLHAPFBO_00784 2e-45 rpmE2 J 50S ribosomal protein L31
NLHAPFBO_00785 1.9e-175 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NLHAPFBO_00786 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
NLHAPFBO_00787 8.9e-155 gst O Glutathione S-transferase
NLHAPFBO_00788 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NLHAPFBO_00789 4.5e-111 tdk 2.7.1.21 F thymidine kinase
NLHAPFBO_00790 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NLHAPFBO_00791 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NLHAPFBO_00792 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NLHAPFBO_00793 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NLHAPFBO_00794 6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
NLHAPFBO_00795 2.4e-107 pvaA M lytic transglycosylase activity
NLHAPFBO_00796 0.0 yfiB1 V abc transporter atp-binding protein
NLHAPFBO_00797 0.0 XK27_10035 V abc transporter atp-binding protein
NLHAPFBO_00798 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
NLHAPFBO_00799 9.3e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLHAPFBO_00800 4.6e-238 dltB M Membrane protein involved in D-alanine export
NLHAPFBO_00801 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLHAPFBO_00802 5.2e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NLHAPFBO_00803 2.5e-250 L Transposase
NLHAPFBO_00804 0.0 3.6.3.8 P cation transport ATPase
NLHAPFBO_00805 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
NLHAPFBO_00806 5.1e-106 V Abi-like protein
NLHAPFBO_00807 1.7e-146 2.1.1.37 H cytosine-specific methyltransferase
NLHAPFBO_00808 2.6e-72 hpaIIR 3.1.21.4 L HpaII restriction endonuclease
NLHAPFBO_00809 3e-44 ymbI L transposase activity
NLHAPFBO_00810 4e-22 L Belongs to the 'phage' integrase family
NLHAPFBO_00811 1.4e-66 S tRNA_anti-like
NLHAPFBO_00812 2e-103
NLHAPFBO_00814 2.3e-12
NLHAPFBO_00816 2e-296 S DNA primase
NLHAPFBO_00817 3e-164 KL Phage plasmid primase P4 family
NLHAPFBO_00818 6.9e-22
NLHAPFBO_00823 5.5e-17 K TRANSCRIPTIONal
NLHAPFBO_00824 6e-39 K Helix-turn-helix
NLHAPFBO_00825 7.1e-217 sip L Belongs to the 'phage' integrase family
NLHAPFBO_00827 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NLHAPFBO_00828 7.3e-166 metF 1.5.1.20 C reductase
NLHAPFBO_00829 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NLHAPFBO_00830 1.6e-92 panT S ECF transporter, substrate-specific component
NLHAPFBO_00831 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NLHAPFBO_00832 6.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
NLHAPFBO_00833 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NLHAPFBO_00834 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLHAPFBO_00835 4.3e-41 T PhoQ Sensor
NLHAPFBO_00836 1.1e-13 T PhoQ Sensor
NLHAPFBO_00837 9.2e-110 T PhoQ Sensor
NLHAPFBO_00838 1.2e-165 L integrase core domain
NLHAPFBO_00839 4.7e-117 L Transposase
NLHAPFBO_00840 2.1e-30 rpsT J rRNA binding
NLHAPFBO_00841 2.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
NLHAPFBO_00842 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
NLHAPFBO_00843 1.3e-24 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
NLHAPFBO_00844 7.5e-101 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NLHAPFBO_00845 5.5e-29 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NLHAPFBO_00846 1.5e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NLHAPFBO_00847 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NLHAPFBO_00848 1.5e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NLHAPFBO_00849 2.7e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NLHAPFBO_00850 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
NLHAPFBO_00851 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
NLHAPFBO_00852 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NLHAPFBO_00853 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NLHAPFBO_00854 3.1e-81 ypmB S Protein conserved in bacteria
NLHAPFBO_00855 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NLHAPFBO_00856 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NLHAPFBO_00857 1.5e-07
NLHAPFBO_00858 2.4e-30
NLHAPFBO_00859 3e-13
NLHAPFBO_00860 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
NLHAPFBO_00861 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NLHAPFBO_00862 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NLHAPFBO_00863 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NLHAPFBO_00864 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NLHAPFBO_00865 4.2e-18 D nuclear chromosome segregation
NLHAPFBO_00866 5.3e-136 yejC S cyclic nucleotide-binding protein
NLHAPFBO_00867 1.2e-163 rapZ S Displays ATPase and GTPase activities
NLHAPFBO_00868 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NLHAPFBO_00869 8.7e-162 whiA K May be required for sporulation
NLHAPFBO_00870 8e-90 pepD E Dipeptidase
NLHAPFBO_00871 5.8e-41 pepD E dipeptidase activity
NLHAPFBO_00872 5.4e-32 cspD K Cold shock protein domain
NLHAPFBO_00873 1.6e-249 L Transposase
NLHAPFBO_00874 9.4e-43 K Cold-Shock Protein
NLHAPFBO_00875 2.9e-131 L Transposase
NLHAPFBO_00876 8e-59 L Transposase
NLHAPFBO_00877 0.0 copB 3.6.3.4 P P-type ATPase
NLHAPFBO_00878 1.6e-88 L Transposase
NLHAPFBO_00879 6.6e-94 L Transposase
NLHAPFBO_00880 4.4e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NLHAPFBO_00881 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NLHAPFBO_00882 3.5e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NLHAPFBO_00883 3.3e-98 cysE 2.3.1.30 E serine acetyltransferase
NLHAPFBO_00884 6.3e-54 L Transposase
NLHAPFBO_00885 5.4e-104 L Transposase
NLHAPFBO_00886 5.2e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
NLHAPFBO_00887 5.2e-113 hsdM 2.1.1.72 V type I restriction-modification system
NLHAPFBO_00888 2.9e-154 glcU U Glucose uptake
NLHAPFBO_00889 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
NLHAPFBO_00890 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
NLHAPFBO_00891 3.7e-88 XK27_10720 D peptidase activity
NLHAPFBO_00892 2.1e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
NLHAPFBO_00893 1.7e-08
NLHAPFBO_00894 1.5e-170 yeiH S Membrane
NLHAPFBO_00895 1.9e-119 mur1 NU muramidase
NLHAPFBO_00896 6.6e-71 L transposition
NLHAPFBO_00897 4.5e-166 cpsY K Transcriptional regulator
NLHAPFBO_00898 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NLHAPFBO_00899 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
NLHAPFBO_00900 5.3e-105 artQ P ABC transporter (Permease
NLHAPFBO_00901 3.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLHAPFBO_00902 1.4e-158 aatB ET ABC transporter substrate-binding protein
NLHAPFBO_00903 3.1e-142 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLHAPFBO_00904 2.3e-62 adhP 1.1.1.1 C alcohol dehydrogenase
NLHAPFBO_00905 7.4e-110 adhP 1.1.1.1 C alcohol dehydrogenase
NLHAPFBO_00907 1.1e-20
NLHAPFBO_00908 0.0 res_1 3.1.21.5 S Type III restriction
NLHAPFBO_00909 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
NLHAPFBO_00910 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NLHAPFBO_00911 2e-126 gntR1 K transcriptional
NLHAPFBO_00912 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NLHAPFBO_00913 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NLHAPFBO_00914 2.4e-87 niaX
NLHAPFBO_00915 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
NLHAPFBO_00916 6.9e-127 K DNA-binding helix-turn-helix protein
NLHAPFBO_00917 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NLHAPFBO_00918 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLHAPFBO_00919 1.1e-167 GK ROK family
NLHAPFBO_00920 2.4e-158 dprA LU DNA protecting protein DprA
NLHAPFBO_00921 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLHAPFBO_00922 5.1e-153 S TraX protein
NLHAPFBO_00923 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLHAPFBO_00924 6.9e-251 T PhoQ Sensor
NLHAPFBO_00925 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NLHAPFBO_00926 1.9e-152 XK27_05470 E Methionine synthase
NLHAPFBO_00927 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NLHAPFBO_00928 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLHAPFBO_00929 6.8e-51 IQ Acetoin reductase
NLHAPFBO_00930 3.9e-19 IQ Acetoin reductase
NLHAPFBO_00931 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NLHAPFBO_00935 4.1e-53 K peptidyl-tyrosine sulfation
NLHAPFBO_00936 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NLHAPFBO_00939 1.3e-212 pqqE C radical SAM domain protein
NLHAPFBO_00940 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
NLHAPFBO_00941 6.6e-61 EGP Major facilitator Superfamily
NLHAPFBO_00942 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NLHAPFBO_00943 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NLHAPFBO_00944 1e-193 L Transposase
NLHAPFBO_00945 6.1e-13 L Transposase
NLHAPFBO_00947 1.2e-97 K Transcriptional regulator, TetR family
NLHAPFBO_00948 1.2e-158 czcD P cation diffusion facilitator family transporter
NLHAPFBO_00949 1e-209 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NLHAPFBO_00950 8.1e-52 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NLHAPFBO_00951 2.7e-106 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NLHAPFBO_00952 6e-08 S Hydrolases of the alpha beta superfamily
NLHAPFBO_00953 1.8e-16 S Alpha/beta hydrolase of unknown function (DUF915)
NLHAPFBO_00954 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
NLHAPFBO_00957 2.6e-143 2.4.2.3 F Phosphorylase superfamily
NLHAPFBO_00958 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
NLHAPFBO_00959 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
NLHAPFBO_00960 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
NLHAPFBO_00961 9.6e-72 dinF V Mate efflux family protein
NLHAPFBO_00962 6.3e-12 dinF V Mate efflux family protein
NLHAPFBO_00963 5.1e-26 dinF V drug transmembrane transporter activity
NLHAPFBO_00964 6.5e-266 S Psort location CytoplasmicMembrane, score
NLHAPFBO_00965 1.7e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NLHAPFBO_00967 2.1e-98 S TraX protein
NLHAPFBO_00968 3.2e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
NLHAPFBO_00969 6.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NLHAPFBO_00970 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NLHAPFBO_00971 1.8e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLHAPFBO_00972 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLHAPFBO_00973 1.3e-131 cas6 S CRISPR-associated endoribonuclease Cas6
NLHAPFBO_00974 0.0 csm1 S CRISPR-associated protein Csm1 family
NLHAPFBO_00975 5.6e-62 csm2 L Pfam:DUF310
NLHAPFBO_00976 1.1e-116 csm3 L RAMP superfamily
NLHAPFBO_00977 1.4e-164 csm4 L CRISPR-associated RAMP protein, Csm4 family
NLHAPFBO_00978 1.9e-203 csm5 L CRISPR-associated RAMP protein, Csm5 family
NLHAPFBO_00979 1.3e-60 csm6 S Psort location Cytoplasmic, score
NLHAPFBO_00980 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NLHAPFBO_00981 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLHAPFBO_00982 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
NLHAPFBO_00984 7.9e-266 dtpT E transporter
NLHAPFBO_00985 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
NLHAPFBO_00986 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
NLHAPFBO_00987 1.8e-67 yecS P ABC transporter (Permease
NLHAPFBO_00989 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NLHAPFBO_00990 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
NLHAPFBO_00991 1.4e-104 yfiF3 K sequence-specific DNA binding
NLHAPFBO_00992 1.3e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NLHAPFBO_00993 1.8e-240 agcS E (Alanine) symporter
NLHAPFBO_00994 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NLHAPFBO_00995 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
NLHAPFBO_00996 1.8e-59 Q phosphatase activity
NLHAPFBO_00997 9.3e-62 S haloacid dehalogenase-like hydrolase
NLHAPFBO_00998 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NLHAPFBO_00999 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
NLHAPFBO_01000 3.6e-136 XK27_04775 S hemerythrin HHE cation binding domain
NLHAPFBO_01001 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
NLHAPFBO_01002 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NLHAPFBO_01003 2.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NLHAPFBO_01004 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NLHAPFBO_01005 1.9e-43 yktA S Belongs to the UPF0223 family
NLHAPFBO_01006 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NLHAPFBO_01007 1.5e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NLHAPFBO_01008 4.3e-158 pstS P phosphate
NLHAPFBO_01009 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
NLHAPFBO_01010 5.9e-155 pstA P phosphate transport system permease
NLHAPFBO_01011 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLHAPFBO_01012 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLHAPFBO_01013 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
NLHAPFBO_01014 0.0 pepN 3.4.11.2 E aminopeptidase
NLHAPFBO_01015 1.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NLHAPFBO_01016 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
NLHAPFBO_01018 3.7e-09
NLHAPFBO_01019 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NLHAPFBO_01020 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NLHAPFBO_01021 2.3e-23 L Transposase
NLHAPFBO_01022 4.6e-25 tatA U protein secretion
NLHAPFBO_01023 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NLHAPFBO_01024 3.9e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
NLHAPFBO_01025 1.5e-233 ycdB P peroxidase
NLHAPFBO_01026 4.6e-152 ycdO P periplasmic lipoprotein involved in iron transport
NLHAPFBO_01027 6.5e-177 fatB P ABC-type enterochelin transport system, periplasmic component
NLHAPFBO_01028 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
NLHAPFBO_01029 1.9e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLHAPFBO_01030 4e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLHAPFBO_01031 2e-139 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NLHAPFBO_01032 3.8e-54 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NLHAPFBO_01033 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NLHAPFBO_01034 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NLHAPFBO_01035 1.9e-37 3.5.1.28 NU amidase activity
NLHAPFBO_01036 8.5e-266 3.5.1.28 NU amidase activity
NLHAPFBO_01037 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NLHAPFBO_01038 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NLHAPFBO_01039 0.0 lpdA 1.8.1.4 C Dehydrogenase
NLHAPFBO_01040 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NLHAPFBO_01041 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NLHAPFBO_01042 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NLHAPFBO_01043 5e-38 P membrane protein (DUF2207)
NLHAPFBO_01044 4.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
NLHAPFBO_01045 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NLHAPFBO_01046 7.2e-126 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NLHAPFBO_01047 4e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLHAPFBO_01048 5.4e-19 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NLHAPFBO_01049 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NLHAPFBO_01050 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
NLHAPFBO_01051 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
NLHAPFBO_01052 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
NLHAPFBO_01053 1.1e-158 rssA S Phospholipase, patatin family
NLHAPFBO_01054 1.9e-59 estA E GDSL-like protein
NLHAPFBO_01055 5.5e-34 estA E Lysophospholipase L1 and related esterases
NLHAPFBO_01056 8.5e-290 S unusual protein kinase
NLHAPFBO_01057 4.9e-39 S granule-associated protein
NLHAPFBO_01058 3.2e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLHAPFBO_01059 2.4e-98 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLHAPFBO_01060 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLHAPFBO_01061 1.1e-198 S hmm pf01594
NLHAPFBO_01062 2.5e-99 G Belongs to the phosphoglycerate mutase family
NLHAPFBO_01063 7.2e-104 G Belongs to the phosphoglycerate mutase family
NLHAPFBO_01064 1.1e-95 pgm G Belongs to the phosphoglycerate mutase family
NLHAPFBO_01065 5.6e-65 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
NLHAPFBO_01066 5.4e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NLHAPFBO_01067 2.2e-94 V VanZ like family
NLHAPFBO_01068 3.1e-37 L Transposase
NLHAPFBO_01069 6.2e-112 L the current gene model (or a revised gene model) may contain a frame shift
NLHAPFBO_01070 6.4e-33 cpsJ S Glycosyltransferase like family 2
NLHAPFBO_01071 7.8e-16
NLHAPFBO_01072 6.5e-72 M Glycosyltransferase sugar-binding region containing DXD motif
NLHAPFBO_01073 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
NLHAPFBO_01074 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
NLHAPFBO_01075 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
NLHAPFBO_01076 3.3e-37 L transposase activity
NLHAPFBO_01077 1.1e-60 L Integrase core domain
NLHAPFBO_01078 3.2e-71 L COG2801 Transposase and inactivated derivatives
NLHAPFBO_01079 1.1e-235 cps1C S Polysaccharide biosynthesis protein
NLHAPFBO_01080 1.3e-23 L Transposase
NLHAPFBO_01081 1.3e-199 L Transposase
NLHAPFBO_01082 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
NLHAPFBO_01083 8.8e-139 L Integrase core domain
NLHAPFBO_01084 2.2e-22 L Transposase
NLHAPFBO_01085 9.7e-23 rgpAc GT4 M group 1 family protein
NLHAPFBO_01086 1.7e-249 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NLHAPFBO_01087 1.4e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
NLHAPFBO_01088 1.1e-103 cps4C M biosynthesis protein
NLHAPFBO_01089 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
NLHAPFBO_01090 4.2e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
NLHAPFBO_01091 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
NLHAPFBO_01092 4.1e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
NLHAPFBO_01093 2.2e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
NLHAPFBO_01094 6.1e-36 clcA_2 P chloride channel
NLHAPFBO_01095 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NLHAPFBO_01096 9.6e-47 S Protein of unknown function (DUF1697)
NLHAPFBO_01097 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NLHAPFBO_01098 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NLHAPFBO_01100 1.5e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
NLHAPFBO_01101 2.4e-275 pepV 3.5.1.18 E Dipeptidase
NLHAPFBO_01102 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NLHAPFBO_01103 1.7e-47 XK27_03610 K Gnat family
NLHAPFBO_01104 1.6e-24 L Transposase
NLHAPFBO_01105 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NLHAPFBO_01106 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NLHAPFBO_01107 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NLHAPFBO_01108 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NLHAPFBO_01109 3.9e-15 M LysM domain
NLHAPFBO_01110 2.9e-90 ebsA S Family of unknown function (DUF5322)
NLHAPFBO_01111 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NLHAPFBO_01112 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NLHAPFBO_01113 4.9e-224 G COG0457 FOG TPR repeat
NLHAPFBO_01114 1.3e-178 yubA S permease
NLHAPFBO_01115 1.7e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
NLHAPFBO_01116 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NLHAPFBO_01117 2.5e-124 ftsE D cell division ATP-binding protein FtsE
NLHAPFBO_01118 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NLHAPFBO_01119 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NLHAPFBO_01120 9.2e-183 yjjH S Calcineurin-like phosphoesterase
NLHAPFBO_01121 1.7e-134 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NLHAPFBO_01122 0.0 pacL 3.6.3.8 P cation transport ATPase
NLHAPFBO_01123 2.6e-67 ywiB S Domain of unknown function (DUF1934)
NLHAPFBO_01124 8.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
NLHAPFBO_01125 4.6e-146 yidA S hydrolases of the HAD superfamily
NLHAPFBO_01126 5.3e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
NLHAPFBO_01127 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
NLHAPFBO_01128 1.5e-247 vicK 2.7.13.3 T Histidine kinase
NLHAPFBO_01129 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLHAPFBO_01130 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLHAPFBO_01131 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NLHAPFBO_01132 8e-115 gltJ P ABC transporter (Permease
NLHAPFBO_01133 4.2e-110 tcyB_2 P ABC transporter (permease)
NLHAPFBO_01134 2.4e-124 endA F DNA RNA non-specific endonuclease
NLHAPFBO_01135 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
NLHAPFBO_01136 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLHAPFBO_01138 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NLHAPFBO_01139 5.9e-26 G Domain of unknown function (DUF4832)
NLHAPFBO_01140 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NLHAPFBO_01141 1.6e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NLHAPFBO_01142 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLHAPFBO_01143 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NLHAPFBO_01144 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NLHAPFBO_01145 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
NLHAPFBO_01146 5.8e-80
NLHAPFBO_01148 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NLHAPFBO_01149 3.5e-206 XK27_05110 P Chloride transporter ClC family
NLHAPFBO_01150 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
NLHAPFBO_01151 1.3e-282 clcA P Chloride transporter, ClC family
NLHAPFBO_01152 2.3e-75 fld C Flavodoxin
NLHAPFBO_01153 3.3e-14 XK27_08880
NLHAPFBO_01154 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
NLHAPFBO_01155 1.6e-151 estA CE1 S Putative esterase
NLHAPFBO_01156 3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLHAPFBO_01157 4.4e-135 XK27_08845 S abc transporter atp-binding protein
NLHAPFBO_01158 2.2e-146 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
NLHAPFBO_01159 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
NLHAPFBO_01160 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
NLHAPFBO_01161 6.1e-28 Q the current gene model (or a revised gene model) may contain a frame shift
NLHAPFBO_01164 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NLHAPFBO_01165 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NLHAPFBO_01166 0.0 dnaE 2.7.7.7 L DNA polymerase
NLHAPFBO_01167 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
NLHAPFBO_01168 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NLHAPFBO_01169 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NLHAPFBO_01170 2.5e-43 ysdA L Membrane
NLHAPFBO_01171 7.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NLHAPFBO_01172 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NLHAPFBO_01173 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLHAPFBO_01174 1.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
NLHAPFBO_01176 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NLHAPFBO_01177 1.7e-83 ypmS S Protein conserved in bacteria
NLHAPFBO_01178 3.9e-143 ypmR E lipolytic protein G-D-S-L family
NLHAPFBO_01179 1e-148 DegV S DegV family
NLHAPFBO_01180 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
NLHAPFBO_01181 3.7e-73 argR K Regulates arginine biosynthesis genes
NLHAPFBO_01182 4.7e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NLHAPFBO_01183 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NLHAPFBO_01184 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
NLHAPFBO_01185 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLHAPFBO_01188 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NLHAPFBO_01189 2.9e-125 dnaD
NLHAPFBO_01190 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NLHAPFBO_01191 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NLHAPFBO_01192 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NLHAPFBO_01193 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NLHAPFBO_01194 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NLHAPFBO_01195 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NLHAPFBO_01196 7.8e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NLHAPFBO_01197 5.6e-240 rodA D Belongs to the SEDS family
NLHAPFBO_01198 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
NLHAPFBO_01199 1.2e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NLHAPFBO_01200 1e-108 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NLHAPFBO_01201 8.3e-21 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NLHAPFBO_01202 2.2e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NLHAPFBO_01203 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NLHAPFBO_01204 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NLHAPFBO_01205 2.6e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NLHAPFBO_01206 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NLHAPFBO_01207 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NLHAPFBO_01208 1.6e-154 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NLHAPFBO_01209 1.5e-29 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NLHAPFBO_01211 3.9e-223 L Transposase
NLHAPFBO_01212 8.2e-26 L Integrase core domain protein
NLHAPFBO_01213 1.6e-55 L transposition
NLHAPFBO_01214 8.2e-22 L Transposase
NLHAPFBO_01215 5.2e-36 L transposase activity
NLHAPFBO_01216 1.3e-22 XK27_08085
NLHAPFBO_01217 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NLHAPFBO_01218 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NLHAPFBO_01219 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NLHAPFBO_01220 1.1e-121 ylfI S tigr01906
NLHAPFBO_01221 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NLHAPFBO_01222 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
NLHAPFBO_01223 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
NLHAPFBO_01226 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NLHAPFBO_01227 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NLHAPFBO_01228 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NLHAPFBO_01229 2.1e-207 yurR 1.4.5.1 E oxidoreductase
NLHAPFBO_01230 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
NLHAPFBO_01231 8.1e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NLHAPFBO_01232 7.9e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NLHAPFBO_01233 1.3e-70 gtrA S GtrA-like protein
NLHAPFBO_01234 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLHAPFBO_01235 2.3e-168 ybbR S Protein conserved in bacteria
NLHAPFBO_01236 1.2e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NLHAPFBO_01237 1.1e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
NLHAPFBO_01238 8.7e-150 cobQ S glutamine amidotransferase
NLHAPFBO_01239 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLHAPFBO_01240 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
NLHAPFBO_01241 6.3e-13 MA20_06245 S yiaA/B two helix domain
NLHAPFBO_01243 0.0 uup S abc transporter atp-binding protein
NLHAPFBO_01244 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NLHAPFBO_01245 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
NLHAPFBO_01246 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NLHAPFBO_01247 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
NLHAPFBO_01248 1.6e-249 L Transposase
NLHAPFBO_01249 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLHAPFBO_01250 7.9e-39 ptsH G phosphocarrier protein Hpr
NLHAPFBO_01251 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
NLHAPFBO_01252 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
NLHAPFBO_01253 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NLHAPFBO_01254 2.2e-34 nrdH O Glutaredoxin
NLHAPFBO_01255 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLHAPFBO_01256 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLHAPFBO_01258 4.2e-71 L Transposase (IS116 IS110 IS902 family)
NLHAPFBO_01259 8.8e-60 L Transposase (IS116 IS110 IS902 family)
NLHAPFBO_01260 5.3e-165 ypuA S secreted protein
NLHAPFBO_01261 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
NLHAPFBO_01262 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
NLHAPFBO_01263 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLHAPFBO_01264 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NLHAPFBO_01265 3.4e-258 noxE P NADH oxidase
NLHAPFBO_01266 1.9e-294 yfmM S abc transporter atp-binding protein
NLHAPFBO_01267 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
NLHAPFBO_01268 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NLHAPFBO_01269 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NLHAPFBO_01270 2e-86 S ECF-type riboflavin transporter, S component
NLHAPFBO_01272 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NLHAPFBO_01273 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
NLHAPFBO_01276 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLHAPFBO_01277 4.6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLHAPFBO_01278 1.2e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NLHAPFBO_01279 0.0 smc D Required for chromosome condensation and partitioning
NLHAPFBO_01280 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NLHAPFBO_01281 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLHAPFBO_01282 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NLHAPFBO_01283 6.1e-87 alkD L Dna alkylation repair
NLHAPFBO_01284 2.4e-92 pat 2.3.1.183 M acetyltransferase
NLHAPFBO_01285 1.5e-12
NLHAPFBO_01286 3.1e-30
NLHAPFBO_01287 2.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLHAPFBO_01288 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NLHAPFBO_01289 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NLHAPFBO_01290 1.2e-62 bioY S biotin transmembrane transporter activity
NLHAPFBO_01291 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
NLHAPFBO_01292 1.5e-138 proV E abc transporter atp-binding protein
NLHAPFBO_01293 7.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
NLHAPFBO_01294 3e-111 proWZ P ABC transporter (Permease
NLHAPFBO_01295 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
NLHAPFBO_01296 1.4e-133 S Protein of unknown function (DUF917)
NLHAPFBO_01297 1.2e-48 S Protein of unknown function (DUF917)
NLHAPFBO_01298 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NLHAPFBO_01299 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
NLHAPFBO_01300 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLHAPFBO_01301 1.5e-192 desK 2.7.13.3 T Histidine kinase
NLHAPFBO_01302 1.4e-133 yvfS V ABC-2 type transporter
NLHAPFBO_01303 8.7e-159 XK27_09825 V abc transporter atp-binding protein
NLHAPFBO_01307 6.6e-213 EGP Major facilitator Superfamily
NLHAPFBO_01308 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
NLHAPFBO_01309 4.6e-152 mutR K Transcriptional activator, Rgg GadR MutR family
NLHAPFBO_01310 4.6e-42 3.6.1.55 F NUDIX domain
NLHAPFBO_01311 1.4e-220 L Transposase
NLHAPFBO_01313 3.7e-122 S An automated process has identified a potential problem with this gene model
NLHAPFBO_01314 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
NLHAPFBO_01315 1.4e-15 liaI KT membrane
NLHAPFBO_01316 2.6e-30 liaI KT membrane
NLHAPFBO_01317 6.1e-93 XK27_05000 S metal cluster binding
NLHAPFBO_01318 0.0 V ABC transporter (permease)
NLHAPFBO_01319 1.9e-133 macB2 V ABC transporter, ATP-binding protein
NLHAPFBO_01320 6.2e-166 T Histidine kinase
NLHAPFBO_01321 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLHAPFBO_01322 3.2e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NLHAPFBO_01324 2.1e-192 pbuX F xanthine permease
NLHAPFBO_01325 4.5e-247 norM V Multidrug efflux pump
NLHAPFBO_01326 2.2e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLHAPFBO_01327 6.6e-235 brnQ E Component of the transport system for branched-chain amino acids
NLHAPFBO_01328 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
NLHAPFBO_01329 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
NLHAPFBO_01330 4.8e-25 csbD K CsbD-like
NLHAPFBO_01332 4e-227 yfnA E amino acid
NLHAPFBO_01333 5.1e-110 XK27_02070 S nitroreductase
NLHAPFBO_01334 9.5e-150 1.13.11.2 S glyoxalase
NLHAPFBO_01335 5.6e-77 ywnA K Transcriptional regulator
NLHAPFBO_01336 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
NLHAPFBO_01337 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLHAPFBO_01338 1.4e-110 drgA C Nitroreductase
NLHAPFBO_01339 3e-102 yoaK S Protein of unknown function (DUF1275)
NLHAPFBO_01340 6.8e-161 yvgN C reductase
NLHAPFBO_01341 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NLHAPFBO_01342 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
NLHAPFBO_01344 1.1e-37 BP1961 P nitric oxide dioxygenase activity
NLHAPFBO_01345 1.4e-54 K response regulator
NLHAPFBO_01346 9.3e-72 S Signal peptide protein, YSIRK family
NLHAPFBO_01348 4.5e-61
NLHAPFBO_01349 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLHAPFBO_01350 1e-137
NLHAPFBO_01351 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
NLHAPFBO_01352 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
NLHAPFBO_01353 5.8e-109 MA20_06410 E LysE type translocator
NLHAPFBO_01354 5.6e-08
NLHAPFBO_01355 2.7e-09
NLHAPFBO_01356 0.0 M family 8
NLHAPFBO_01358 5e-161 hrtB V MacB-like periplasmic core domain
NLHAPFBO_01359 1.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
NLHAPFBO_01360 1.1e-151 V MatE
NLHAPFBO_01362 3.9e-110 C Fe-S oxidoreductases
NLHAPFBO_01363 1.2e-176 EGP Major Facilitator Superfamily
NLHAPFBO_01364 5.5e-258 I radical SAM domain protein
NLHAPFBO_01366 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NLHAPFBO_01367 1.4e-150 L Integrase core domain protein
NLHAPFBO_01368 1.8e-87 L transposase activity
NLHAPFBO_01370 1.4e-84
NLHAPFBO_01371 0.0 sbcC L ATPase involved in DNA repair
NLHAPFBO_01372 1.3e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NLHAPFBO_01373 0.0 lacL 3.2.1.23 G -beta-galactosidase
NLHAPFBO_01374 0.0 lacS G transporter
NLHAPFBO_01375 2.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NLHAPFBO_01376 3.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NLHAPFBO_01377 1.3e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NLHAPFBO_01378 3.7e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NLHAPFBO_01379 2.3e-184 galR K Transcriptional regulator
NLHAPFBO_01380 2.7e-08 L Integrase core domain protein
NLHAPFBO_01381 1.2e-25 L transposition
NLHAPFBO_01382 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NLHAPFBO_01383 5.1e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NLHAPFBO_01384 2.5e-101 V abc transporter atp-binding protein
NLHAPFBO_01385 4.3e-40 V abc transporter atp-binding protein
NLHAPFBO_01386 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NLHAPFBO_01387 6.4e-62 L Transposase
NLHAPFBO_01388 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NLHAPFBO_01389 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NLHAPFBO_01390 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NLHAPFBO_01391 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NLHAPFBO_01392 8.6e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NLHAPFBO_01393 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NLHAPFBO_01394 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NLHAPFBO_01397 8.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NLHAPFBO_01398 1.9e-173 vraS 2.7.13.3 T Histidine kinase
NLHAPFBO_01399 9.1e-119 yvqF KT membrane
NLHAPFBO_01400 1.7e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
NLHAPFBO_01401 9e-133 stp 3.1.3.16 T phosphatase
NLHAPFBO_01402 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NLHAPFBO_01403 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLHAPFBO_01404 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NLHAPFBO_01405 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
NLHAPFBO_01406 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NLHAPFBO_01407 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NLHAPFBO_01408 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
NLHAPFBO_01409 5.3e-147 supH S overlaps another CDS with the same product name
NLHAPFBO_01410 8.6e-63 yvoA_1 K Transcriptional
NLHAPFBO_01411 9.8e-121 skfE V abc transporter atp-binding protein
NLHAPFBO_01412 9e-131 V ATPase activity
NLHAPFBO_01413 4.3e-172 oppF P Belongs to the ABC transporter superfamily
NLHAPFBO_01414 2.2e-204 oppD P Belongs to the ABC transporter superfamily
NLHAPFBO_01415 2.4e-167 amiD P ABC transporter (Permease
NLHAPFBO_01416 1.1e-270 amiC P ABC transporter (Permease
NLHAPFBO_01417 7.2e-242 amiA E ABC transporter, substrate-binding protein, family 5
NLHAPFBO_01418 2.2e-109 amiA E ABC transporter, substrate-binding protein, family 5
NLHAPFBO_01419 8.1e-45 L Transposase
NLHAPFBO_01420 4.1e-158 L COG2801 Transposase and inactivated derivatives
NLHAPFBO_01421 1.2e-24 oppF P Belongs to the ABC transporter superfamily
NLHAPFBO_01422 5.5e-23 oppF P Belongs to the ABC transporter superfamily
NLHAPFBO_01423 2e-21 tatD L hydrolase, TatD family'
NLHAPFBO_01425 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
NLHAPFBO_01426 4e-110 L PFAM Integrase catalytic region
NLHAPFBO_01427 9.3e-29 L transposition
NLHAPFBO_01428 1.4e-38 L transposase activity
NLHAPFBO_01429 3.7e-38 L transposase activity
NLHAPFBO_01430 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NLHAPFBO_01431 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NLHAPFBO_01432 1.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLHAPFBO_01433 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
NLHAPFBO_01434 5.8e-103 yjbK S Adenylate cyclase
NLHAPFBO_01435 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLHAPFBO_01436 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
NLHAPFBO_01437 9e-59 XK27_04120 S Putative amino acid metabolism
NLHAPFBO_01438 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NLHAPFBO_01439 1.6e-131 puuD T peptidase C26
NLHAPFBO_01440 6.2e-120 radC E Belongs to the UPF0758 family
NLHAPFBO_01441 0.0 rgpF M Rhamnan synthesis protein F
NLHAPFBO_01442 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NLHAPFBO_01443 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NLHAPFBO_01444 1.1e-142 rgpC GM Transport permease protein
NLHAPFBO_01445 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
NLHAPFBO_01446 1.3e-226 rgpA GT4 M Domain of unknown function (DUF1972)
NLHAPFBO_01447 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
NLHAPFBO_01448 2.6e-220 amrA S polysaccharide biosynthetic process
NLHAPFBO_01449 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
NLHAPFBO_01450 7.6e-126 ycbB S Glycosyl transferase family 2
NLHAPFBO_01451 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NLHAPFBO_01452 1.2e-231
NLHAPFBO_01453 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NLHAPFBO_01454 5.4e-251 M Psort location CytoplasmicMembrane, score
NLHAPFBO_01455 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
NLHAPFBO_01456 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NLHAPFBO_01457 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NLHAPFBO_01458 1.1e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NLHAPFBO_01459 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NLHAPFBO_01460 7.9e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
NLHAPFBO_01461 3.4e-200 arcT 2.6.1.1 E Aminotransferase
NLHAPFBO_01462 7.2e-136 ET ABC transporter
NLHAPFBO_01463 2.8e-143 ET Belongs to the bacterial solute-binding protein 3 family
NLHAPFBO_01464 2.9e-84 mutT 3.6.1.55 F Nudix family
NLHAPFBO_01465 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NLHAPFBO_01466 2.5e-56 V CAAX protease self-immunity
NLHAPFBO_01467 2.4e-33 S CAAX amino terminal protease family protein
NLHAPFBO_01468 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NLHAPFBO_01469 6.7e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLHAPFBO_01470 1.1e-16 XK27_00735
NLHAPFBO_01471 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NLHAPFBO_01473 1.6e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLHAPFBO_01476 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
NLHAPFBO_01477 4e-50 ycaO O OsmC-like protein
NLHAPFBO_01478 1.1e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
NLHAPFBO_01480 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
NLHAPFBO_01481 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLHAPFBO_01482 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLHAPFBO_01483 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NLHAPFBO_01484 7.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
NLHAPFBO_01485 2.8e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NLHAPFBO_01486 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLHAPFBO_01487 2.6e-109 3.1.3.18 S IA, variant 1
NLHAPFBO_01488 2.2e-117 lrgB M effector of murein hydrolase
NLHAPFBO_01489 2.2e-58 lrgA S Effector of murein hydrolase LrgA
NLHAPFBO_01491 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
NLHAPFBO_01492 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NLHAPFBO_01493 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLHAPFBO_01494 3.9e-104 wecD M Acetyltransferase GNAT family
NLHAPFBO_01495 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NLHAPFBO_01496 2.6e-95 GK ROK family
NLHAPFBO_01497 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
NLHAPFBO_01498 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
NLHAPFBO_01499 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
NLHAPFBO_01500 2.3e-206 potD P spermidine putrescine ABC transporter
NLHAPFBO_01501 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
NLHAPFBO_01502 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
NLHAPFBO_01503 6.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NLHAPFBO_01504 7.8e-171 murB 1.3.1.98 M cell wall formation
NLHAPFBO_01505 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NLHAPFBO_01506 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NLHAPFBO_01507 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
NLHAPFBO_01508 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NLHAPFBO_01509 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
NLHAPFBO_01510 0.0 ydaO E amino acid
NLHAPFBO_01511 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NLHAPFBO_01512 4.1e-37 ylqC L Belongs to the UPF0109 family
NLHAPFBO_01513 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NLHAPFBO_01514 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
NLHAPFBO_01515 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
NLHAPFBO_01516 2.1e-74 S QueT transporter
NLHAPFBO_01517 1.9e-55 L Transposase
NLHAPFBO_01518 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NLHAPFBO_01519 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLHAPFBO_01520 3.7e-85 ccl S cog cog4708
NLHAPFBO_01521 7.4e-164 rbn E Belongs to the UPF0761 family
NLHAPFBO_01522 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NLHAPFBO_01523 3.3e-231 ytoI K transcriptional regulator containing CBS domains
NLHAPFBO_01524 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NLHAPFBO_01525 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLHAPFBO_01526 0.0 comEC S Competence protein ComEC
NLHAPFBO_01527 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NLHAPFBO_01528 8.3e-142 plsC 2.3.1.51 I Acyltransferase
NLHAPFBO_01529 1.7e-77 nodB3 G polysaccharide deacetylase
NLHAPFBO_01530 2.3e-139 yabB 2.1.1.223 L Methyltransferase
NLHAPFBO_01531 1e-41 yazA L endonuclease containing a URI domain
NLHAPFBO_01533 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NLHAPFBO_01534 2.3e-154 corA P CorA-like protein
NLHAPFBO_01535 1.9e-62 yjqA S Bacterial PH domain
NLHAPFBO_01536 7.8e-100 thiT S Thiamine transporter
NLHAPFBO_01537 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NLHAPFBO_01538 1.6e-200 yjbB G Permeases of the major facilitator superfamily
NLHAPFBO_01539 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NLHAPFBO_01540 7.9e-120 ywaF S Integral membrane protein (intg_mem_TP0381)
NLHAPFBO_01541 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NLHAPFBO_01545 1.1e-155 cjaA ET ABC transporter substrate-binding protein
NLHAPFBO_01546 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
NLHAPFBO_01547 3e-106 P ABC transporter (Permease
NLHAPFBO_01548 6e-115 papP P ABC transporter (Permease
NLHAPFBO_01549 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NLHAPFBO_01550 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
NLHAPFBO_01551 0.0 copA 3.6.3.54 P P-type ATPase
NLHAPFBO_01552 2.7e-73 copY K Copper transport repressor, CopY TcrY family
NLHAPFBO_01553 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NLHAPFBO_01554 2.1e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NLHAPFBO_01555 3e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
NLHAPFBO_01556 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NLHAPFBO_01557 1.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NLHAPFBO_01558 2.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
NLHAPFBO_01559 1.5e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NLHAPFBO_01560 1.6e-55
NLHAPFBO_01561 0.0 ctpE P E1-E2 ATPase
NLHAPFBO_01562 6.1e-27
NLHAPFBO_01563 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NLHAPFBO_01564 5.1e-47 L transposase activity
NLHAPFBO_01565 5.3e-119 K transcriptional regulator, MerR family
NLHAPFBO_01566 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
NLHAPFBO_01567 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
NLHAPFBO_01568 7.4e-64 XK27_02560 S cog cog2151
NLHAPFBO_01569 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NLHAPFBO_01570 7.7e-227 ytfP S Flavoprotein
NLHAPFBO_01572 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NLHAPFBO_01573 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
NLHAPFBO_01574 1.6e-183 ecsB U ABC transporter
NLHAPFBO_01575 2.3e-133 ecsA V abc transporter atp-binding protein
NLHAPFBO_01576 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NLHAPFBO_01577 4.8e-11
NLHAPFBO_01578 6.5e-55
NLHAPFBO_01579 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
NLHAPFBO_01580 2.7e-202 ylbM S Belongs to the UPF0348 family
NLHAPFBO_01581 2e-140 yqeM Q Methyltransferase domain protein
NLHAPFBO_01582 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NLHAPFBO_01583 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NLHAPFBO_01584 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NLHAPFBO_01585 3.5e-49 yhbY J RNA-binding protein
NLHAPFBO_01586 6.4e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NLHAPFBO_01587 1.8e-98 yqeG S hydrolase of the HAD superfamily
NLHAPFBO_01588 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NLHAPFBO_01589 4e-59
NLHAPFBO_01590 8.7e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLHAPFBO_01591 1.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NLHAPFBO_01592 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLHAPFBO_01593 9.8e-25 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
NLHAPFBO_01594 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
NLHAPFBO_01595 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLHAPFBO_01596 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLHAPFBO_01597 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLHAPFBO_01598 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
NLHAPFBO_01599 3.4e-100 pncA Q isochorismatase
NLHAPFBO_01600 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NLHAPFBO_01601 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
NLHAPFBO_01602 2.4e-75 XK27_03180 T universal stress protein
NLHAPFBO_01605 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLHAPFBO_01606 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
NLHAPFBO_01607 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
NLHAPFBO_01608 0.0 yjcE P NhaP-type Na H and K H antiporters
NLHAPFBO_01610 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
NLHAPFBO_01611 1.3e-184 yhcC S radical SAM protein
NLHAPFBO_01612 8.4e-196 ylbL T Belongs to the peptidase S16 family
NLHAPFBO_01613 2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NLHAPFBO_01614 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
NLHAPFBO_01615 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NLHAPFBO_01616 6.1e-08 S Protein of unknown function (DUF4059)
NLHAPFBO_01617 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
NLHAPFBO_01618 1.4e-159 yxeN P ABC transporter (Permease
NLHAPFBO_01619 8.8e-153 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NLHAPFBO_01621 1.3e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLHAPFBO_01622 0.0 pflB 2.3.1.54 C formate acetyltransferase'
NLHAPFBO_01623 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
NLHAPFBO_01624 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLHAPFBO_01625 7.2e-46 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
NLHAPFBO_01626 1.4e-33 D nuclear chromosome segregation
NLHAPFBO_01627 1.5e-127 ybbM S transport system, permease component
NLHAPFBO_01628 4.4e-115 ybbL S abc transporter atp-binding protein
NLHAPFBO_01629 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
NLHAPFBO_01630 4.6e-140 cppA E CppA N-terminal
NLHAPFBO_01631 5e-44 V CAAX protease self-immunity
NLHAPFBO_01632 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NLHAPFBO_01633 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NLHAPFBO_01636 3e-47 spiA K sequence-specific DNA binding
NLHAPFBO_01637 2.9e-28 blpT
NLHAPFBO_01638 6.7e-98 blpT
NLHAPFBO_01639 4.7e-117 L Transposase
NLHAPFBO_01640 1.2e-165 L integrase core domain
NLHAPFBO_01642 4.4e-132 agrA KT phosphorelay signal transduction system
NLHAPFBO_01643 1.4e-237 blpH 2.7.13.3 T protein histidine kinase activity
NLHAPFBO_01645 4e-235 mesE M Transport protein ComB
NLHAPFBO_01646 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NLHAPFBO_01647 0.0 mdlB V abc transporter atp-binding protein
NLHAPFBO_01648 0.0 mdlA V abc transporter atp-binding protein
NLHAPFBO_01650 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
NLHAPFBO_01651 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NLHAPFBO_01652 2.4e-66 yutD J protein conserved in bacteria
NLHAPFBO_01653 4.8e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NLHAPFBO_01655 1.1e-250 L Transposase
NLHAPFBO_01656 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NLHAPFBO_01657 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLHAPFBO_01658 0.0 ftsI 3.4.16.4 M penicillin-binding protein
NLHAPFBO_01659 8.1e-46 ftsL D cell division protein FtsL
NLHAPFBO_01660 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NLHAPFBO_01661 2.2e-85
NLHAPFBO_01662 3.4e-58
NLHAPFBO_01663 2.8e-21 yhaI J Protein of unknown function (DUF805)
NLHAPFBO_01664 4.5e-18 D nuclear chromosome segregation
NLHAPFBO_01665 6.9e-210 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NLHAPFBO_01666 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLHAPFBO_01667 9.2e-284 XK27_00765
NLHAPFBO_01668 2.1e-129 ecsA_2 V abc transporter atp-binding protein
NLHAPFBO_01669 9.3e-122 S Protein of unknown function (DUF554)
NLHAPFBO_01670 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NLHAPFBO_01671 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NLHAPFBO_01672 3.4e-57 liaI S membrane
NLHAPFBO_01673 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
NLHAPFBO_01674 8.5e-68 KT response to antibiotic
NLHAPFBO_01675 3.5e-17 KT response to antibiotic
NLHAPFBO_01676 1.6e-79 yebC M Membrane
NLHAPFBO_01677 2.9e-18 yebC M Membrane
NLHAPFBO_01678 7.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
NLHAPFBO_01679 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NLHAPFBO_01680 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NLHAPFBO_01681 1.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLHAPFBO_01682 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NLHAPFBO_01683 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NLHAPFBO_01684 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NLHAPFBO_01685 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLHAPFBO_01687 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NLHAPFBO_01688 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
NLHAPFBO_01689 0.0 scrA 2.7.1.211 G pts system
NLHAPFBO_01690 4.1e-291 scrB 3.2.1.26 GH32 G invertase
NLHAPFBO_01691 6.2e-45 scrR K Transcriptional
NLHAPFBO_01692 5.6e-115 scrR K Transcriptional
NLHAPFBO_01693 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NLHAPFBO_01694 3.4e-62 yqhY S protein conserved in bacteria
NLHAPFBO_01695 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLHAPFBO_01696 1.1e-83 comEB 3.5.4.12 F ComE operon protein 2
NLHAPFBO_01697 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
NLHAPFBO_01700 7.7e-11 V 'abc transporter, ATP-binding protein
NLHAPFBO_01703 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NLHAPFBO_01704 2e-169 corA P COG0598 Mg2 and Co2 transporters
NLHAPFBO_01705 3.1e-124 XK27_01040 S Pfam PF06570
NLHAPFBO_01707 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NLHAPFBO_01708 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NLHAPFBO_01709 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
NLHAPFBO_01710 3.6e-41 XK27_05745
NLHAPFBO_01711 2.5e-230 mutY L A G-specific adenine glycosylase
NLHAPFBO_01716 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLHAPFBO_01717 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NLHAPFBO_01718 1e-93 cvpA S toxin biosynthetic process
NLHAPFBO_01719 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NLHAPFBO_01720 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLHAPFBO_01721 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NLHAPFBO_01722 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NLHAPFBO_01723 8.8e-48 azlD E branched-chain amino acid
NLHAPFBO_01724 2.6e-113 azlC E AzlC protein
NLHAPFBO_01725 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NLHAPFBO_01726 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NLHAPFBO_01727 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
NLHAPFBO_01728 2.5e-33 ykzG S Belongs to the UPF0356 family
NLHAPFBO_01729 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLHAPFBO_01730 2.7e-40 pscB M CHAP domain protein
NLHAPFBO_01731 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
NLHAPFBO_01732 8.5e-63 glnR K Transcriptional regulator
NLHAPFBO_01733 1.3e-87 S Fusaric acid resistance protein-like
NLHAPFBO_01734 1.5e-12
NLHAPFBO_01735 3.1e-30
NLHAPFBO_01736 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NLHAPFBO_01737 5.7e-43 L transposase activity
NLHAPFBO_01738 5e-17 L Transposase
NLHAPFBO_01739 1.1e-53 L transposition
NLHAPFBO_01740 2.9e-87 L Integrase core domain protein
NLHAPFBO_01741 1.8e-187 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NLHAPFBO_01742 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NLHAPFBO_01743 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NLHAPFBO_01744 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NLHAPFBO_01745 5.3e-142 purR 2.4.2.7 F operon repressor
NLHAPFBO_01746 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
NLHAPFBO_01747 6.9e-173 rmuC S RmuC domain protein
NLHAPFBO_01748 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
NLHAPFBO_01749 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NLHAPFBO_01750 4.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NLHAPFBO_01752 6.2e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NLHAPFBO_01753 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NLHAPFBO_01754 1.6e-143 tatD L Hydrolase, tatd
NLHAPFBO_01755 1.1e-50 trxA O Belongs to the thioredoxin family
NLHAPFBO_01756 1.9e-141 S Macro domain protein
NLHAPFBO_01757 2e-09 L thioesterase
NLHAPFBO_01758 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
NLHAPFBO_01762 6.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NLHAPFBO_01763 1.1e-83 L Transposase
NLHAPFBO_01764 1e-13 rpmH J Ribosomal protein L34
NLHAPFBO_01765 2e-186 jag S RNA-binding protein
NLHAPFBO_01766 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLHAPFBO_01767 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NLHAPFBO_01768 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
NLHAPFBO_01769 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NLHAPFBO_01770 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLHAPFBO_01771 6.7e-81 amiA E transmembrane transport
NLHAPFBO_01772 7.3e-69 amiA E transmembrane transport
NLHAPFBO_01773 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NLHAPFBO_01774 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NLHAPFBO_01775 9.2e-51 S Protein of unknown function (DUF3397)
NLHAPFBO_01776 1.2e-165 L integrase core domain
NLHAPFBO_01777 3.9e-122 L Transposase
NLHAPFBO_01778 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NLHAPFBO_01779 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
NLHAPFBO_01780 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
NLHAPFBO_01781 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NLHAPFBO_01782 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NLHAPFBO_01783 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
NLHAPFBO_01784 2.5e-77 XK27_09620 S reductase
NLHAPFBO_01785 9e-62 XK27_09615 C reductase
NLHAPFBO_01786 2.3e-141 XK27_09615 C reductase
NLHAPFBO_01787 3.2e-62 fnt P Formate nitrite transporter
NLHAPFBO_01788 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
NLHAPFBO_01789 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NLHAPFBO_01790 2.5e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NLHAPFBO_01791 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NLHAPFBO_01792 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NLHAPFBO_01793 1.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NLHAPFBO_01794 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NLHAPFBO_01795 2.7e-48 S glycolate biosynthetic process
NLHAPFBO_01796 3.4e-64 S phosphatase activity
NLHAPFBO_01797 2e-157 rrmA 2.1.1.187 Q methyltransferase
NLHAPFBO_01800 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NLHAPFBO_01801 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NLHAPFBO_01802 6.4e-37 yeeD O sulfur carrier activity
NLHAPFBO_01803 3.8e-190 yeeE S Sulphur transport
NLHAPFBO_01804 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLHAPFBO_01805 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NLHAPFBO_01806 1.8e-09 S Domain of unknown function (DUF4651)
NLHAPFBO_01807 7.5e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NLHAPFBO_01808 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLHAPFBO_01809 8.9e-104 L Transposase
NLHAPFBO_01810 5.3e-136 L Transposase
NLHAPFBO_01811 8.7e-111 S CAAX amino terminal protease family protein
NLHAPFBO_01813 1.1e-66 V CAAX protease self-immunity
NLHAPFBO_01814 5.9e-28 V CAAX protease self-immunity
NLHAPFBO_01815 2.6e-26 lanR K sequence-specific DNA binding
NLHAPFBO_01816 8.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLHAPFBO_01817 1.5e-175 ytxK 2.1.1.72 L DNA methylase
NLHAPFBO_01818 5.2e-13 comGF U Putative Competence protein ComGF
NLHAPFBO_01819 1.3e-70 comGF U Competence protein ComGF
NLHAPFBO_01820 1.4e-15 NU Type II secretory pathway pseudopilin
NLHAPFBO_01821 1.8e-57 cglD NU Competence protein
NLHAPFBO_01822 8.5e-43 comGC U Required for transformation and DNA binding
NLHAPFBO_01823 8.8e-145 cglB NU type II secretion system
NLHAPFBO_01824 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NLHAPFBO_01825 2.9e-68 S cog cog4699
NLHAPFBO_01826 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLHAPFBO_01827 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLHAPFBO_01828 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLHAPFBO_01829 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NLHAPFBO_01830 1.5e-194 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NLHAPFBO_01831 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
NLHAPFBO_01832 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
NLHAPFBO_01833 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NLHAPFBO_01834 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
NLHAPFBO_01835 1.8e-57 asp S cog cog1302
NLHAPFBO_01836 7.1e-226 norN V Mate efflux family protein
NLHAPFBO_01837 1.2e-277 thrC 4.2.3.1 E Threonine synthase
NLHAPFBO_01838 6.1e-64 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NLHAPFBO_01839 4.1e-22 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NLHAPFBO_01840 7.3e-74 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NLHAPFBO_01841 1.2e-133 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NLHAPFBO_01842 2.1e-52 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
NLHAPFBO_01843 0.0 pepO 3.4.24.71 O Peptidase family M13
NLHAPFBO_01844 1.5e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NLHAPFBO_01845 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NLHAPFBO_01846 1.4e-54 treB 2.7.1.201 G PTS System
NLHAPFBO_01847 5.8e-21 treR K DNA-binding transcription factor activity
NLHAPFBO_01848 1.2e-85 treR K trehalose operon
NLHAPFBO_01849 3.3e-95 ywlG S Belongs to the UPF0340 family
NLHAPFBO_01852 2e-35 L PFAM Integrase, catalytic core
NLHAPFBO_01853 2e-94 L PFAM Integrase, catalytic core
NLHAPFBO_01854 3.3e-46 K Putative DNA-binding domain
NLHAPFBO_01855 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
NLHAPFBO_01856 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NLHAPFBO_01857 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
NLHAPFBO_01862 1e-39
NLHAPFBO_01863 6.5e-31
NLHAPFBO_01864 5e-31 S Hypothetical protein (DUF2513)
NLHAPFBO_01865 7.7e-13
NLHAPFBO_01867 5.7e-217 S MvaI/BcnI restriction endonuclease family
NLHAPFBO_01869 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
NLHAPFBO_01870 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
NLHAPFBO_01872 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
NLHAPFBO_01873 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
NLHAPFBO_01874 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
NLHAPFBO_01875 3.3e-09 L PFAM Integrase, catalytic core
NLHAPFBO_01876 1.8e-111 L PFAM Integrase, catalytic core
NLHAPFBO_01877 3.3e-62 rplQ J ribosomal protein l17
NLHAPFBO_01878 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLHAPFBO_01879 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NLHAPFBO_01880 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NLHAPFBO_01881 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NLHAPFBO_01882 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NLHAPFBO_01883 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NLHAPFBO_01884 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NLHAPFBO_01885 4.4e-58 rplO J binds to the 23S rRNA
NLHAPFBO_01886 2.5e-23 rpmD J ribosomal protein l30
NLHAPFBO_01887 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NLHAPFBO_01888 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NLHAPFBO_01889 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NLHAPFBO_01890 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NLHAPFBO_01891 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLHAPFBO_01892 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NLHAPFBO_01893 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NLHAPFBO_01894 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NLHAPFBO_01895 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NLHAPFBO_01896 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
NLHAPFBO_01897 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NLHAPFBO_01898 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NLHAPFBO_01899 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NLHAPFBO_01900 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NLHAPFBO_01901 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NLHAPFBO_01902 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NLHAPFBO_01903 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
NLHAPFBO_01904 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NLHAPFBO_01905 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NLHAPFBO_01906 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NLHAPFBO_01907 0.0 XK27_09800 I Acyltransferase
NLHAPFBO_01908 1.7e-35 XK27_09805 S MORN repeat protein
NLHAPFBO_01909 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLHAPFBO_01910 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NLHAPFBO_01911 1.8e-50 adk 2.7.4.3 F topology modulation protein
NLHAPFBO_01912 7.6e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLHAPFBO_01913 9.7e-30 S Domain of unknown function (DUF4649)
NLHAPFBO_01914 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NLHAPFBO_01915 3.2e-56 Z012_04635 K sequence-specific DNA binding
NLHAPFBO_01916 1.4e-59 Z012_04635 K sequence-specific DNA binding
NLHAPFBO_01918 7.5e-109 C Radical SAM
NLHAPFBO_01919 3e-104 C Radical SAM
NLHAPFBO_01920 3.9e-287 V ABC transporter transmembrane region
NLHAPFBO_01921 1e-155 L Replication initiation factor
NLHAPFBO_01922 1.9e-18 S Domain of unknown function (DUF3173)
NLHAPFBO_01923 1.7e-215 int L Belongs to the 'phage' integrase family
NLHAPFBO_01925 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NLHAPFBO_01926 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NLHAPFBO_01927 2.8e-44 yrzL S Belongs to the UPF0297 family
NLHAPFBO_01928 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NLHAPFBO_01929 4.2e-44 yrzB S Belongs to the UPF0473 family
NLHAPFBO_01930 2.8e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
NLHAPFBO_01931 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NLHAPFBO_01932 7.5e-14
NLHAPFBO_01933 2.6e-91 XK27_10930 K acetyltransferase
NLHAPFBO_01934 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLHAPFBO_01935 1.8e-147 yaaA S Belongs to the UPF0246 family
NLHAPFBO_01936 9.3e-167 XK27_01785 S cog cog1284
NLHAPFBO_01937 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NLHAPFBO_01939 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
NLHAPFBO_01940 1.4e-53 metE 2.1.1.14 E Methionine synthase
NLHAPFBO_01941 5.2e-55 metE 2.1.1.14 E Methionine synthase
NLHAPFBO_01942 1.4e-36 metE 2.1.1.14 E Methionine synthase
NLHAPFBO_01943 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NLHAPFBO_01944 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NLHAPFBO_01945 2.4e-28
NLHAPFBO_01946 0.0 V Type II restriction enzyme, methylase subunits
NLHAPFBO_01947 3.2e-10 S Sigma-70, region 4
NLHAPFBO_01948 1.7e-35
NLHAPFBO_01949 1.5e-160 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NLHAPFBO_01950 2e-20
NLHAPFBO_01951 2.1e-82 S Plasmid replication protein
NLHAPFBO_01952 5.9e-20 S MerR HTH family regulatory protein
NLHAPFBO_01953 5.1e-184 sip L Belongs to the 'phage' integrase family
NLHAPFBO_01956 1.5e-49 yegS 2.7.1.107 I lipid kinase activity
NLHAPFBO_01957 2.7e-95 S Hydrophobic domain protein
NLHAPFBO_01959 3.7e-27 S Membrane
NLHAPFBO_01960 9.1e-101
NLHAPFBO_01961 1.8e-23 S Small integral membrane protein
NLHAPFBO_01962 3.1e-85 M Protein conserved in bacteria
NLHAPFBO_01963 1.1e-11 K CsbD-like
NLHAPFBO_01964 3.4e-13 nudL L hydrolase
NLHAPFBO_01965 4e-19 K negative regulation of transcription, DNA-templated
NLHAPFBO_01966 1.7e-23 K negative regulation of transcription, DNA-templated
NLHAPFBO_01968 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
NLHAPFBO_01969 1.2e-87 S Putative adhesin
NLHAPFBO_01970 3.9e-161 XK27_06930 V domain protein
NLHAPFBO_01971 6.4e-96 XK27_06935 K transcriptional regulator
NLHAPFBO_01972 4.8e-55 ypaA M Membrane
NLHAPFBO_01973 2.7e-08
NLHAPFBO_01974 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NLHAPFBO_01975 8.2e-48 veg S Biofilm formation stimulator VEG
NLHAPFBO_01976 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NLHAPFBO_01977 3.9e-70 rplI J binds to the 23S rRNA
NLHAPFBO_01978 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NLHAPFBO_01979 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NLHAPFBO_01980 1.5e-77 F NUDIX domain
NLHAPFBO_01981 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NLHAPFBO_01982 0.0 S Bacterial membrane protein, YfhO
NLHAPFBO_01983 1.7e-63 isaA GH23 M Immunodominant staphylococcal antigen A
NLHAPFBO_01984 5.3e-85 lytE M LysM domain protein
NLHAPFBO_01985 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLHAPFBO_01986 2e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLHAPFBO_01987 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLHAPFBO_01988 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLHAPFBO_01989 6.3e-138 ymfM S sequence-specific DNA binding
NLHAPFBO_01990 9.4e-92 ymfH S Peptidase M16
NLHAPFBO_01991 1e-99 ymfH S Peptidase M16
NLHAPFBO_01992 1.3e-156 ymfF S Peptidase M16
NLHAPFBO_01993 1.7e-66 ymfF S Peptidase M16
NLHAPFBO_01994 1.6e-45 yaaA S S4 domain protein YaaA
NLHAPFBO_01995 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NLHAPFBO_01996 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NLHAPFBO_01997 3.1e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NLHAPFBO_01998 4.2e-153 yvjA S membrane
NLHAPFBO_01999 6.7e-306 ybiT S abc transporter atp-binding protein
NLHAPFBO_02000 0.0 XK27_10405 S Bacterial membrane protein YfhO
NLHAPFBO_02004 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
NLHAPFBO_02005 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NLHAPFBO_02006 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NLHAPFBO_02007 8.5e-134 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)