ORF_ID e_value Gene_name EC_number CAZy COGs Description
IKJKALAH_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IKJKALAH_00002 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IKJKALAH_00003 1.1e-29 yyzM S Protein conserved in bacteria
IKJKALAH_00004 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IKJKALAH_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IKJKALAH_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IKJKALAH_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IKJKALAH_00008 2.7e-61 divIC D Septum formation initiator
IKJKALAH_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
IKJKALAH_00011 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IKJKALAH_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IKJKALAH_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IKJKALAH_00014 1.3e-137 L Transposase
IKJKALAH_00015 1.1e-92 L Transposase
IKJKALAH_00016 1.6e-55 L transposition
IKJKALAH_00017 1.9e-86 L Integrase core domain protein
IKJKALAH_00030 5.3e-11
IKJKALAH_00036 5.5e-139 mreC M Involved in formation and maintenance of cell shape
IKJKALAH_00037 9.1e-87 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IKJKALAH_00038 5.5e-94 usp 3.5.1.28 CBM50 S CHAP domain
IKJKALAH_00039 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IKJKALAH_00040 2.9e-218 araT 2.6.1.1 E Aminotransferase
IKJKALAH_00041 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
IKJKALAH_00042 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IKJKALAH_00043 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IKJKALAH_00044 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IKJKALAH_00045 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IKJKALAH_00046 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IKJKALAH_00047 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IKJKALAH_00048 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IKJKALAH_00049 1.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IKJKALAH_00050 1e-90 L transposase activity
IKJKALAH_00051 3.5e-50 L transposition
IKJKALAH_00052 2e-32 L Integrase core domain protein
IKJKALAH_00053 2.3e-161 S CHAP domain
IKJKALAH_00054 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
IKJKALAH_00055 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IKJKALAH_00056 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IKJKALAH_00057 2e-140 1.1.1.169 H Ketopantoate reductase
IKJKALAH_00058 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IKJKALAH_00059 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IKJKALAH_00060 1.2e-09 L Transposase
IKJKALAH_00061 4.2e-35 amiA E ABC transporter, substrate-binding protein, family 5
IKJKALAH_00062 1.6e-249 L Transposase
IKJKALAH_00063 1.1e-156 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IKJKALAH_00064 8.8e-48 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IKJKALAH_00065 8.4e-205 nodC 2.4.1.212 GT2 M Chitin synthase
IKJKALAH_00066 9e-89 FNV0100 F Belongs to the Nudix hydrolase family
IKJKALAH_00067 3.5e-28 3.4.13.21 I Protein conserved in bacteria
IKJKALAH_00070 1.2e-57 T Toxic component of a toxin-antitoxin (TA) module
IKJKALAH_00072 8.2e-70 argR K Regulates arginine biosynthesis genes
IKJKALAH_00073 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IKJKALAH_00074 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IKJKALAH_00075 1.9e-80 S Protein of unknown function (DUF3021)
IKJKALAH_00076 6.5e-63 KT phosphorelay signal transduction system
IKJKALAH_00078 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IKJKALAH_00080 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IKJKALAH_00081 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
IKJKALAH_00082 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
IKJKALAH_00083 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IKJKALAH_00084 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
IKJKALAH_00090 2.6e-10
IKJKALAH_00093 1.9e-07
IKJKALAH_00098 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IKJKALAH_00099 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IKJKALAH_00100 5.5e-36 XK27_02060 S Transglycosylase associated protein
IKJKALAH_00101 2.6e-55 badR K DNA-binding transcription factor activity
IKJKALAH_00102 3.5e-97 S reductase
IKJKALAH_00103 6.9e-89 L Integrase core domain protein
IKJKALAH_00104 6.4e-41 L transposition
IKJKALAH_00106 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
IKJKALAH_00107 3.2e-68 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IKJKALAH_00110 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
IKJKALAH_00111 3e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IKJKALAH_00112 1.1e-83 S Putative small multi-drug export protein
IKJKALAH_00113 6.2e-76 ctsR K Belongs to the CtsR family
IKJKALAH_00114 0.0 clpC O Belongs to the ClpA ClpB family
IKJKALAH_00115 1.5e-62 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IKJKALAH_00116 5.1e-71 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IKJKALAH_00117 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IKJKALAH_00118 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IKJKALAH_00119 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IKJKALAH_00120 7.9e-106 S SseB protein N-terminal domain
IKJKALAH_00121 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
IKJKALAH_00122 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IKJKALAH_00123 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IKJKALAH_00126 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IKJKALAH_00127 3.5e-91 yacP S RNA-binding protein containing a PIN domain
IKJKALAH_00128 3.4e-155 degV S DegV family
IKJKALAH_00130 1.8e-31 K helix-turn-helix
IKJKALAH_00131 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IKJKALAH_00132 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IKJKALAH_00133 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IKJKALAH_00134 1.5e-35 K sequence-specific DNA binding
IKJKALAH_00136 0.0 S Lantibiotic dehydratase, C terminus
IKJKALAH_00137 9.1e-231 spaC2 V Lanthionine synthetase C family protein
IKJKALAH_00138 2.5e-183 EGP Major facilitator Superfamily
IKJKALAH_00139 5.9e-24 3.6.4.12
IKJKALAH_00140 2.9e-90 3.6.4.12 K Divergent AAA domain protein
IKJKALAH_00141 5.9e-222 int L Belongs to the 'phage' integrase family
IKJKALAH_00142 2.8e-39 S Helix-turn-helix domain
IKJKALAH_00143 4.9e-173
IKJKALAH_00145 3.4e-75 isp2 S pathogenesis
IKJKALAH_00146 5.7e-91 tnp L Transposase
IKJKALAH_00147 3.3e-225 capA M Bacterial capsule synthesis protein
IKJKALAH_00148 3.6e-39 gcvR T UPF0237 protein
IKJKALAH_00149 1.9e-242 XK27_08635 S UPF0210 protein
IKJKALAH_00150 2.2e-38 ais G alpha-ribazole phosphatase activity
IKJKALAH_00151 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IKJKALAH_00152 1.3e-102 acmA 3.2.1.17 NU amidase activity
IKJKALAH_00153 5.8e-197 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IKJKALAH_00154 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IKJKALAH_00155 7.5e-298 dnaK O Heat shock 70 kDa protein
IKJKALAH_00156 9.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IKJKALAH_00157 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IKJKALAH_00158 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
IKJKALAH_00159 1.7e-60 hmpT S membrane
IKJKALAH_00162 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IKJKALAH_00163 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IKJKALAH_00164 1e-84
IKJKALAH_00165 1.6e-77 sigH K DNA-templated transcription, initiation
IKJKALAH_00166 9.3e-150 ykuT M mechanosensitive ion channel
IKJKALAH_00167 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IKJKALAH_00168 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IKJKALAH_00169 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IKJKALAH_00170 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
IKJKALAH_00171 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
IKJKALAH_00172 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
IKJKALAH_00173 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IKJKALAH_00174 1.4e-42 F nucleotide catabolic process
IKJKALAH_00175 9.2e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IKJKALAH_00176 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IKJKALAH_00177 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IKJKALAH_00178 1.8e-83 nrdI F Belongs to the NrdI family
IKJKALAH_00179 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IKJKALAH_00180 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IKJKALAH_00181 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IKJKALAH_00182 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IKJKALAH_00183 5.6e-59 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IKJKALAH_00184 1.9e-45 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IKJKALAH_00185 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IKJKALAH_00186 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IKJKALAH_00187 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IKJKALAH_00188 9.3e-201 yhjX P Major Facilitator
IKJKALAH_00189 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IKJKALAH_00190 4.2e-93 V VanZ like family
IKJKALAH_00192 1e-123 glnQ E abc transporter atp-binding protein
IKJKALAH_00193 5.8e-275 glnP P ABC transporter
IKJKALAH_00194 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IKJKALAH_00195 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IKJKALAH_00196 7.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
IKJKALAH_00197 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IKJKALAH_00198 6.3e-235 sufD O assembly protein SufD
IKJKALAH_00199 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IKJKALAH_00200 1.2e-73 nifU C SUF system FeS assembly protein, NifU family
IKJKALAH_00201 2.2e-273 sufB O assembly protein SufB
IKJKALAH_00202 7e-10 oppA E ABC transporter substrate-binding protein
IKJKALAH_00203 2.3e-139 oppA E ABC transporter substrate-binding protein
IKJKALAH_00204 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKJKALAH_00205 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKJKALAH_00206 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKJKALAH_00207 2.5e-09 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKJKALAH_00208 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKJKALAH_00209 1.7e-62 oppD P Belongs to the ABC transporter superfamily
IKJKALAH_00210 1.2e-62 oppD P Belongs to the ABC transporter superfamily
IKJKALAH_00211 3.1e-43 oppD P Belongs to the ABC transporter superfamily
IKJKALAH_00212 7.5e-62 oppF P Belongs to the ABC transporter superfamily
IKJKALAH_00213 9.8e-62 oppF P Belongs to the ABC transporter superfamily
IKJKALAH_00214 2.7e-21
IKJKALAH_00215 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IKJKALAH_00216 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IKJKALAH_00217 6e-128 K sequence-specific DNA binding
IKJKALAH_00219 0.0 KLT serine threonine protein kinase
IKJKALAH_00220 1.9e-223 EGP Major facilitator Superfamily
IKJKALAH_00221 3.1e-72 adcR K transcriptional
IKJKALAH_00222 6.4e-136 adcC P ABC transporter, ATP-binding protein
IKJKALAH_00223 2.5e-128 adcB P ABC transporter (Permease
IKJKALAH_00224 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IKJKALAH_00225 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
IKJKALAH_00226 5.1e-149 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
IKJKALAH_00227 1.5e-104 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IKJKALAH_00228 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
IKJKALAH_00229 8.1e-257 pgi 5.3.1.9 G Belongs to the GPI family
IKJKALAH_00230 1.9e-127 yeeN K transcriptional regulatory protein
IKJKALAH_00231 9.8e-50 yajC U protein transport
IKJKALAH_00232 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IKJKALAH_00233 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
IKJKALAH_00234 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IKJKALAH_00235 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IKJKALAH_00236 0.0 WQ51_06230 S ABC transporter substrate binding protein
IKJKALAH_00237 5.2e-142 cmpC S abc transporter atp-binding protein
IKJKALAH_00238 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IKJKALAH_00239 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IKJKALAH_00240 4.4e-37 L Transposase
IKJKALAH_00241 6.4e-18 L transposase activity
IKJKALAH_00242 8.7e-31 L transposition
IKJKALAH_00243 2.1e-82 L Integrase core domain protein
IKJKALAH_00246 4.7e-43
IKJKALAH_00247 6.8e-56 S TM2 domain
IKJKALAH_00248 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IKJKALAH_00249 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IKJKALAH_00250 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IKJKALAH_00251 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
IKJKALAH_00252 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
IKJKALAH_00253 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
IKJKALAH_00254 6e-55 cof Q phosphatase activity
IKJKALAH_00255 1.1e-34 cof Q phosphatase activity
IKJKALAH_00256 4.7e-79 glcR K transcriptional regulator (DeoR family)
IKJKALAH_00257 3.9e-21 glcR K transcriptional regulator (DeoR family)
IKJKALAH_00258 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IKJKALAH_00259 3.8e-40 K transcriptional
IKJKALAH_00261 2.6e-76 S thiolester hydrolase activity
IKJKALAH_00262 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
IKJKALAH_00263 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IKJKALAH_00264 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IKJKALAH_00265 1.9e-77 yhaI L Membrane
IKJKALAH_00266 1.5e-258 pepC 3.4.22.40 E aminopeptidase
IKJKALAH_00267 1.3e-102 L Transposase
IKJKALAH_00268 5.3e-136 L Transposase
IKJKALAH_00269 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IKJKALAH_00270 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IKJKALAH_00271 3.1e-95 ypsA S Belongs to the UPF0398 family
IKJKALAH_00272 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IKJKALAH_00273 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IKJKALAH_00274 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IKJKALAH_00275 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
IKJKALAH_00276 2.5e-23
IKJKALAH_00277 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IKJKALAH_00278 4e-20 XK27_09675 K -acetyltransferase
IKJKALAH_00279 9.3e-46 XK27_09675 K -acetyltransferase
IKJKALAH_00280 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IKJKALAH_00281 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IKJKALAH_00282 5.2e-59 L Integrase core domain protein
IKJKALAH_00283 4.2e-164 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IKJKALAH_00284 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IKJKALAH_00285 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IKJKALAH_00286 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
IKJKALAH_00287 8.8e-98 ybhL S Belongs to the BI1 family
IKJKALAH_00290 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IKJKALAH_00291 1.4e-90 K transcriptional regulator
IKJKALAH_00292 7.6e-36 yneF S UPF0154 protein
IKJKALAH_00293 4.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IKJKALAH_00294 6e-185 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IKJKALAH_00295 3.5e-99 XK27_09740 S Phosphoesterase
IKJKALAH_00296 2.1e-85 ykuL S CBS domain
IKJKALAH_00297 3.7e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IKJKALAH_00298 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IKJKALAH_00299 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IKJKALAH_00300 1.3e-139 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IKJKALAH_00301 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IKJKALAH_00302 1.2e-258 trkH P Cation transport protein
IKJKALAH_00303 1.5e-247 trkA P Potassium transporter peripheral membrane component
IKJKALAH_00304 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IKJKALAH_00305 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IKJKALAH_00306 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
IKJKALAH_00307 5.6e-161 K sequence-specific DNA binding
IKJKALAH_00308 1.2e-32 V protein secretion by the type I secretion system
IKJKALAH_00309 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IKJKALAH_00310 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IKJKALAH_00311 1.1e-34 V protein secretion by the type I secretion system
IKJKALAH_00312 1.8e-27 comA V protein secretion by the type I secretion system
IKJKALAH_00313 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IKJKALAH_00314 3.7e-51 yhaI L Membrane
IKJKALAH_00315 6.7e-36 S Domain of unknown function (DUF4173)
IKJKALAH_00316 9.2e-132 S Domain of unknown function (DUF4173)
IKJKALAH_00317 6.8e-95 ureI S AmiS/UreI family transporter
IKJKALAH_00318 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IKJKALAH_00319 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IKJKALAH_00320 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IKJKALAH_00321 6.6e-78 ureE O enzyme active site formation
IKJKALAH_00322 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IKJKALAH_00323 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IKJKALAH_00324 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IKJKALAH_00325 4.3e-175 cbiM P PDGLE domain
IKJKALAH_00326 1.1e-136 P cobalt transport protein
IKJKALAH_00327 1.6e-131 cbiO P ABC transporter
IKJKALAH_00328 5.3e-153 ET amino acid transport
IKJKALAH_00329 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKJKALAH_00330 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
IKJKALAH_00331 3.8e-205 EGP Transmembrane secretion effector
IKJKALAH_00332 4e-153 ET amino acid transport
IKJKALAH_00333 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
IKJKALAH_00334 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IKJKALAH_00335 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IKJKALAH_00336 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IKJKALAH_00337 7.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IKJKALAH_00338 8.8e-98 metI P ABC transporter (Permease
IKJKALAH_00339 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IKJKALAH_00340 4.7e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
IKJKALAH_00341 9.4e-95 S UPF0397 protein
IKJKALAH_00342 0.0 ykoD P abc transporter atp-binding protein
IKJKALAH_00343 4.7e-146 cbiQ P cobalt transport
IKJKALAH_00344 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IKJKALAH_00345 6.9e-11 ulaG S L-ascorbate 6-phosphate lactonase
IKJKALAH_00346 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
IKJKALAH_00347 2.7e-244 P COG0168 Trk-type K transport systems, membrane components
IKJKALAH_00348 1.2e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
IKJKALAH_00349 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
IKJKALAH_00350 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKJKALAH_00351 2.8e-282 T PhoQ Sensor
IKJKALAH_00352 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IKJKALAH_00353 6.5e-218 dnaB L Replication initiation and membrane attachment
IKJKALAH_00354 4.4e-166 dnaI L Primosomal protein DnaI
IKJKALAH_00355 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IKJKALAH_00357 1.2e-34
IKJKALAH_00358 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
IKJKALAH_00359 3e-27 L Integrase core domain protein
IKJKALAH_00360 3.4e-50 L transposition
IKJKALAH_00361 5.7e-23 L Transposase
IKJKALAH_00362 7.8e-28 L transposase activity
IKJKALAH_00363 2.7e-126 L Transposase
IKJKALAH_00364 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IKJKALAH_00365 4.2e-62 manO S protein conserved in bacteria
IKJKALAH_00366 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
IKJKALAH_00367 2.3e-116 manM G pts system
IKJKALAH_00368 1.1e-181 manL 2.7.1.191 G pts system
IKJKALAH_00369 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
IKJKALAH_00370 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IKJKALAH_00371 1.9e-248 pbuO S permease
IKJKALAH_00372 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
IKJKALAH_00373 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
IKJKALAH_00374 2.8e-219 brpA K Transcriptional
IKJKALAH_00375 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
IKJKALAH_00376 3.1e-212 nusA K Participates in both transcription termination and antitermination
IKJKALAH_00377 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
IKJKALAH_00378 1.4e-41 ylxQ J ribosomal protein
IKJKALAH_00379 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IKJKALAH_00380 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IKJKALAH_00381 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
IKJKALAH_00382 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
IKJKALAH_00383 8.7e-41 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
IKJKALAH_00384 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
IKJKALAH_00385 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IKJKALAH_00386 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
IKJKALAH_00387 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
IKJKALAH_00388 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
IKJKALAH_00389 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IKJKALAH_00391 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IKJKALAH_00392 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IKJKALAH_00393 1.2e-74 ylbF S Belongs to the UPF0342 family
IKJKALAH_00394 7.1e-46 ylbG S UPF0298 protein
IKJKALAH_00395 1.8e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IKJKALAH_00396 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
IKJKALAH_00397 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
IKJKALAH_00398 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IKJKALAH_00399 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IKJKALAH_00400 6.8e-69 acuB S IMP dehydrogenase activity
IKJKALAH_00401 8.9e-41 acuB S IMP dehydrogenase activity
IKJKALAH_00402 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IKJKALAH_00403 1.1e-110 yvyE 3.4.13.9 S YigZ family
IKJKALAH_00404 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IKJKALAH_00405 1.7e-122 comFC S Competence protein
IKJKALAH_00406 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IKJKALAH_00414 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
IKJKALAH_00415 6.4e-108 S Domain of unknown function (DUF1803)
IKJKALAH_00416 7.8e-102 ygaC J Belongs to the UPF0374 family
IKJKALAH_00417 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
IKJKALAH_00418 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IKJKALAH_00419 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
IKJKALAH_00420 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
IKJKALAH_00421 1.9e-115 S Haloacid dehalogenase-like hydrolase
IKJKALAH_00422 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
IKJKALAH_00423 4e-72 marR K Transcriptional regulator, MarR family
IKJKALAH_00424 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IKJKALAH_00425 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IKJKALAH_00426 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
IKJKALAH_00427 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IKJKALAH_00428 1.6e-126 IQ reductase
IKJKALAH_00429 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IKJKALAH_00430 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IKJKALAH_00431 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IKJKALAH_00432 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IKJKALAH_00433 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IKJKALAH_00434 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IKJKALAH_00435 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IKJKALAH_00436 1.1e-65 tnp L Transposase
IKJKALAH_00437 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
IKJKALAH_00438 4.4e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
IKJKALAH_00439 1.3e-07 L Transposase and inactivated derivatives, TnpA family
IKJKALAH_00440 3.4e-35 tnp L Transposase
IKJKALAH_00442 8e-277 S Protein of unknown function (DUF3114)
IKJKALAH_00443 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
IKJKALAH_00444 7.3e-55 V (ABC) transporter
IKJKALAH_00445 5.1e-113 V (ABC) transporter
IKJKALAH_00446 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
IKJKALAH_00447 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
IKJKALAH_00448 3.2e-113 K sequence-specific DNA binding
IKJKALAH_00449 8.4e-155 L COG2801 Transposase and inactivated derivatives
IKJKALAH_00450 6.6e-38 L transposase activity
IKJKALAH_00451 2.3e-205 rny D Endoribonuclease that initiates mRNA decay
IKJKALAH_00452 2.4e-164 L Transposase
IKJKALAH_00453 1.6e-249 L Transposase
IKJKALAH_00454 1.8e-84 L Transposase
IKJKALAH_00455 2.1e-113 fruR K transcriptional
IKJKALAH_00456 4.6e-163 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IKJKALAH_00457 1.6e-78 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
IKJKALAH_00458 7.8e-22 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
IKJKALAH_00459 2.3e-25 fruA 2.7.1.202 G phosphotransferase system
IKJKALAH_00460 2.7e-102 fruA 2.7.1.202 G phosphotransferase system
IKJKALAH_00461 3.2e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IKJKALAH_00462 3.4e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IKJKALAH_00464 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IKJKALAH_00465 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IKJKALAH_00466 1.4e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IKJKALAH_00467 3e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IKJKALAH_00468 4.9e-39 2.3.1.128 K acetyltransferase
IKJKALAH_00469 6.4e-29 2.3.1.128 K acetyltransferase
IKJKALAH_00470 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
IKJKALAH_00471 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IKJKALAH_00472 3e-122 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IKJKALAH_00473 2.3e-60 WQ51_03320 S cog cog4835
IKJKALAH_00474 1.9e-60 XK27_08360 S EDD domain protein, DegV family
IKJKALAH_00475 3.6e-74 XK27_08360 S EDD domain protein, DegV family
IKJKALAH_00476 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IKJKALAH_00477 1.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IKJKALAH_00478 0.0 yfmR S abc transporter atp-binding protein
IKJKALAH_00479 1.6e-24 U response to pH
IKJKALAH_00480 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
IKJKALAH_00481 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
IKJKALAH_00482 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IKJKALAH_00483 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IKJKALAH_00484 1.9e-77 K DNA-binding transcription factor activity
IKJKALAH_00485 0.0 lmrA1 V abc transporter atp-binding protein
IKJKALAH_00486 0.0 lmrA2 V abc transporter atp-binding protein
IKJKALAH_00487 7.1e-37 K Acetyltransferase (GNAT) family
IKJKALAH_00488 4.5e-77 sptS 2.7.13.3 T Histidine kinase
IKJKALAH_00489 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IKJKALAH_00490 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IKJKALAH_00491 5.3e-161 cvfB S Protein conserved in bacteria
IKJKALAH_00492 7.4e-35 yozE S Belongs to the UPF0346 family
IKJKALAH_00493 2.2e-118 sip M LysM domain protein
IKJKALAH_00494 1e-190 phoH T phosphate starvation-inducible protein PhoH
IKJKALAH_00498 1.6e-249 L Transposase
IKJKALAH_00499 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IKJKALAH_00500 1.8e-164 K transcriptional regulator (lysR family)
IKJKALAH_00501 1.4e-186 coiA 3.6.4.12 S Competence protein
IKJKALAH_00502 0.0 pepF E oligoendopeptidase F
IKJKALAH_00503 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
IKJKALAH_00504 1.1e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
IKJKALAH_00505 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IKJKALAH_00506 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IKJKALAH_00507 6.2e-84 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IKJKALAH_00508 3e-63 3.4.17.14, 3.5.1.28 NU amidase activity
IKJKALAH_00509 2.7e-14 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
IKJKALAH_00510 1.5e-23 3.4.17.14, 3.5.1.28 NU amidase activity
IKJKALAH_00511 6.4e-52 3.4.17.14, 3.5.1.28 NU amidase activity
IKJKALAH_00512 2.6e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IKJKALAH_00513 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
IKJKALAH_00514 1.7e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IKJKALAH_00515 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IKJKALAH_00516 1.3e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IKJKALAH_00517 1.2e-208 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IKJKALAH_00518 7.9e-128 yxkH G deacetylase
IKJKALAH_00519 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IKJKALAH_00520 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IKJKALAH_00521 3e-151 rarD S Transporter
IKJKALAH_00522 2.2e-15 T peptidase
IKJKALAH_00523 8.9e-14 coiA 3.6.4.12 S Competence protein
IKJKALAH_00524 1.1e-89 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IKJKALAH_00525 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IKJKALAH_00526 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IKJKALAH_00527 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IKJKALAH_00528 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
IKJKALAH_00529 3.3e-78 atpF C ATP synthase F(0) sector subunit b
IKJKALAH_00530 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IKJKALAH_00531 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IKJKALAH_00532 9.6e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IKJKALAH_00533 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IKJKALAH_00534 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IKJKALAH_00535 2.8e-230 ftsW D Belongs to the SEDS family
IKJKALAH_00536 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IKJKALAH_00537 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IKJKALAH_00538 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IKJKALAH_00539 6.4e-162 holB 2.7.7.7 L dna polymerase iii
IKJKALAH_00540 1.2e-135 yaaT S stage 0 sporulation protein
IKJKALAH_00541 9.5e-55 yabA L Involved in initiation control of chromosome replication
IKJKALAH_00542 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IKJKALAH_00543 5.8e-233 amt P Ammonium Transporter
IKJKALAH_00544 6.6e-54 glnB K Belongs to the P(II) protein family
IKJKALAH_00545 3.2e-105 mur1 NU mannosyl-glycoprotein
IKJKALAH_00546 2.2e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
IKJKALAH_00547 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
IKJKALAH_00548 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IKJKALAH_00549 1.8e-53
IKJKALAH_00550 7.5e-26
IKJKALAH_00551 1.5e-59
IKJKALAH_00552 6.1e-63 S membrane
IKJKALAH_00553 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IKJKALAH_00554 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IKJKALAH_00555 4.5e-39 ynzC S UPF0291 protein
IKJKALAH_00556 1.8e-254 cycA E permease
IKJKALAH_00557 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
IKJKALAH_00558 1.7e-70 pts33BCA G pts system
IKJKALAH_00559 2.5e-119 pts33BCA G pts system
IKJKALAH_00560 9.7e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
IKJKALAH_00561 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IKJKALAH_00566 1.4e-167 fhuR K transcriptional regulator (lysR family)
IKJKALAH_00567 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IKJKALAH_00568 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IKJKALAH_00569 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IKJKALAH_00570 4.9e-227 pyrP F uracil Permease
IKJKALAH_00571 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IKJKALAH_00572 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
IKJKALAH_00573 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
IKJKALAH_00574 5.1e-131 2.1.1.223 S Putative SAM-dependent methyltransferase
IKJKALAH_00575 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IKJKALAH_00576 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IKJKALAH_00577 1.7e-59 V permease protein
IKJKALAH_00578 4.6e-43 V efflux transmembrane transporter activity
IKJKALAH_00579 7.2e-24 ytrF V efflux transmembrane transporter activity
IKJKALAH_00580 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IKJKALAH_00581 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IKJKALAH_00583 0.0 mdlB V abc transporter atp-binding protein
IKJKALAH_00584 0.0 lmrA V abc transporter atp-binding protein
IKJKALAH_00585 6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IKJKALAH_00586 2.6e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IKJKALAH_00587 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
IKJKALAH_00588 2.5e-132 rr02 KT response regulator
IKJKALAH_00589 2.5e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IKJKALAH_00590 2.8e-168 V ABC transporter
IKJKALAH_00591 5.4e-122 sagI S ABC-2 type transporter
IKJKALAH_00592 6.9e-197 yceA S Belongs to the UPF0176 family
IKJKALAH_00593 8e-28 XK27_00085 K Transcriptional
IKJKALAH_00594 1.9e-22
IKJKALAH_00595 1.8e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
IKJKALAH_00596 9.6e-113 S VIT family
IKJKALAH_00597 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IKJKALAH_00598 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IKJKALAH_00599 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
IKJKALAH_00600 5.9e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
IKJKALAH_00601 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IKJKALAH_00602 4.6e-105 GBS0088 J protein conserved in bacteria
IKJKALAH_00603 6.9e-140 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IKJKALAH_00604 1.3e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IKJKALAH_00605 5e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
IKJKALAH_00606 3.4e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IKJKALAH_00607 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IKJKALAH_00608 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
IKJKALAH_00609 2.5e-21
IKJKALAH_00610 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IKJKALAH_00612 3.5e-07 U protein secretion
IKJKALAH_00613 2.1e-50 U protein secretion
IKJKALAH_00614 1.1e-11 U protein secretion
IKJKALAH_00615 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
IKJKALAH_00616 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IKJKALAH_00617 4.9e-21 XK27_13030
IKJKALAH_00618 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IKJKALAH_00619 9.9e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IKJKALAH_00620 9.8e-163 S Protein of unknown function (DUF3114)
IKJKALAH_00621 6.1e-22 S Protein of unknown function (DUF3114)
IKJKALAH_00622 1.5e-118 yqfA K protein, Hemolysin III
IKJKALAH_00623 1e-25 K hmm pf08876
IKJKALAH_00624 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IKJKALAH_00625 1.7e-218 mvaS 2.3.3.10 I synthase
IKJKALAH_00626 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IKJKALAH_00627 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IKJKALAH_00628 9.7e-22
IKJKALAH_00629 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IKJKALAH_00630 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IKJKALAH_00631 2.2e-249 mmuP E amino acid
IKJKALAH_00632 4.5e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
IKJKALAH_00633 1.4e-29 S Domain of unknown function (DUF1912)
IKJKALAH_00634 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
IKJKALAH_00635 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IKJKALAH_00636 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IKJKALAH_00637 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IKJKALAH_00638 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
IKJKALAH_00639 4.8e-16 S Protein of unknown function (DUF2969)
IKJKALAH_00642 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
IKJKALAH_00645 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
IKJKALAH_00646 6.1e-70 M Pfam SNARE associated Golgi protein
IKJKALAH_00647 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
IKJKALAH_00648 9.3e-59 S oxidoreductase
IKJKALAH_00649 9.7e-66 S oxidoreductase
IKJKALAH_00650 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
IKJKALAH_00651 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IKJKALAH_00652 0.0 clpE O Belongs to the ClpA ClpB family
IKJKALAH_00653 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IKJKALAH_00654 1.3e-34 ykuJ S protein conserved in bacteria
IKJKALAH_00655 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
IKJKALAH_00656 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKJKALAH_00657 1.1e-78 feoA P FeoA domain protein
IKJKALAH_00658 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IKJKALAH_00659 1.5e-07
IKJKALAH_00660 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IKJKALAH_00661 2.2e-45 K sequence-specific DNA binding
IKJKALAH_00662 1.5e-35 yugF I carboxylic ester hydrolase activity
IKJKALAH_00663 7.5e-23 I Alpha/beta hydrolase family
IKJKALAH_00664 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IKJKALAH_00665 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IKJKALAH_00666 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
IKJKALAH_00667 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IKJKALAH_00668 5.8e-64 licT K transcriptional antiterminator
IKJKALAH_00669 6.8e-53 licT K transcriptional antiterminator
IKJKALAH_00670 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IKJKALAH_00671 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IKJKALAH_00672 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IKJKALAH_00673 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IKJKALAH_00674 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IKJKALAH_00675 3.6e-219 mdtG EGP Major facilitator Superfamily
IKJKALAH_00676 2e-33 secG U Preprotein translocase subunit SecG
IKJKALAH_00677 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IKJKALAH_00678 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IKJKALAH_00679 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IKJKALAH_00680 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
IKJKALAH_00681 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
IKJKALAH_00682 4.4e-183 ccpA K Catabolite control protein A
IKJKALAH_00683 2.8e-28 yyaQ S YjbR
IKJKALAH_00684 6.6e-101 yyaQ V Protein conserved in bacteria
IKJKALAH_00685 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IKJKALAH_00686 1e-78 yueI S Protein of unknown function (DUF1694)
IKJKALAH_00687 2.8e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IKJKALAH_00688 2e-25 WQ51_00785
IKJKALAH_00689 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IKJKALAH_00690 2e-219 ywbD 2.1.1.191 J Methyltransferase
IKJKALAH_00691 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IKJKALAH_00692 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IKJKALAH_00693 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IKJKALAH_00694 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IKJKALAH_00695 8.3e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IKJKALAH_00696 3.2e-53 yheA S Belongs to the UPF0342 family
IKJKALAH_00697 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IKJKALAH_00698 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IKJKALAH_00699 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IKJKALAH_00700 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
IKJKALAH_00701 6.4e-252 msrR K Transcriptional regulator
IKJKALAH_00702 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
IKJKALAH_00703 2.4e-203 I acyl-CoA dehydrogenase
IKJKALAH_00704 4.5e-97 mip S hydroperoxide reductase activity
IKJKALAH_00705 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IKJKALAH_00706 8.9e-20
IKJKALAH_00707 3.2e-46
IKJKALAH_00708 1e-31 K Cro/C1-type HTH DNA-binding domain
IKJKALAH_00709 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
IKJKALAH_00710 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
IKJKALAH_00711 1.4e-94
IKJKALAH_00712 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IKJKALAH_00713 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IKJKALAH_00714 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IKJKALAH_00715 2.6e-194 S CRISPR-associated protein Csn2 subfamily St
IKJKALAH_00716 7.8e-146 ycgQ S TIGR03943 family
IKJKALAH_00717 7.1e-156 XK27_03015 S permease
IKJKALAH_00719 0.0 yhgF K Transcriptional accessory protein
IKJKALAH_00720 2.2e-41 pspC KT PspC domain
IKJKALAH_00721 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IKJKALAH_00722 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IKJKALAH_00724 5.5e-69 ytxH S General stress protein
IKJKALAH_00726 2e-177 yegQ O Peptidase U32
IKJKALAH_00727 3.4e-252 yegQ O Peptidase U32
IKJKALAH_00728 8.1e-46 S CHY zinc finger
IKJKALAH_00729 8.4e-88 bioY S biotin synthase
IKJKALAH_00731 1.1e-33 XK27_12190 S protein conserved in bacteria
IKJKALAH_00732 5.1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
IKJKALAH_00733 4.8e-11
IKJKALAH_00734 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
IKJKALAH_00735 4.1e-225 mutH L DNA mismatch repair enzyme MutH
IKJKALAH_00736 5.2e-29 S SIR2-like domain
IKJKALAH_00737 1.2e-33 S SIR2-like domain
IKJKALAH_00738 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IKJKALAH_00739 1.9e-15 M LysM domain
IKJKALAH_00740 2.4e-58 M LysM domain
IKJKALAH_00741 3.1e-20
IKJKALAH_00742 5.4e-172 S hydrolase
IKJKALAH_00743 1.5e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
IKJKALAH_00744 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IKJKALAH_00745 5.9e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
IKJKALAH_00746 2.1e-27 P Hemerythrin HHE cation binding domain protein
IKJKALAH_00747 1.4e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKJKALAH_00748 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
IKJKALAH_00749 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
IKJKALAH_00750 8.3e-76 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IKJKALAH_00751 1.4e-44 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IKJKALAH_00752 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
IKJKALAH_00753 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
IKJKALAH_00754 2.3e-85 3.1.21.3 V type I restriction modification DNA specificity domain
IKJKALAH_00755 2.5e-11 prrC S AAA domain
IKJKALAH_00756 3.1e-53 prrC S AAA domain
IKJKALAH_00757 5e-27 prrC S AAA domain
IKJKALAH_00758 1.4e-36 prrC S AAA domain
IKJKALAH_00759 3.4e-49 S PD-(D/E)XK nuclease family transposase
IKJKALAH_00760 6.9e-90 S double-stranded DNA endodeoxyribonuclease activity
IKJKALAH_00761 4.4e-148 spd F DNA RNA non-specific endonuclease
IKJKALAH_00762 1.5e-92 lemA S LemA family
IKJKALAH_00763 1.8e-135 htpX O Belongs to the peptidase M48B family
IKJKALAH_00764 1.8e-73 S Psort location CytoplasmicMembrane, score
IKJKALAH_00765 6.2e-56 S Domain of unknown function (DUF4430)
IKJKALAH_00766 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IKJKALAH_00767 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
IKJKALAH_00768 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
IKJKALAH_00769 2.7e-160 L Transposase
IKJKALAH_00770 3e-50 L Transposase
IKJKALAH_00771 1.4e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
IKJKALAH_00772 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IKJKALAH_00773 3.5e-91 dps P Belongs to the Dps family
IKJKALAH_00774 1.1e-80 perR P Belongs to the Fur family
IKJKALAH_00775 8.4e-28 yqgQ S protein conserved in bacteria
IKJKALAH_00776 2.2e-179 glk 2.7.1.2 G Glucokinase
IKJKALAH_00777 0.0 typA T GTP-binding protein TypA
IKJKALAH_00779 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IKJKALAH_00780 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IKJKALAH_00781 8.2e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IKJKALAH_00782 4.4e-250 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IKJKALAH_00783 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IKJKALAH_00784 7.8e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IKJKALAH_00785 2e-95 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IKJKALAH_00786 1.2e-34 yggT D integral membrane protein
IKJKALAH_00787 1.2e-143 ylmH T S4 RNA-binding domain
IKJKALAH_00788 6.7e-135 divIVA D Cell division protein DivIVA
IKJKALAH_00789 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IKJKALAH_00790 5.5e-30
IKJKALAH_00791 8.4e-10
IKJKALAH_00792 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
IKJKALAH_00793 2e-45 rpmE2 J 50S ribosomal protein L31
IKJKALAH_00794 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IKJKALAH_00795 3e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
IKJKALAH_00796 1.5e-154 gst O Glutathione S-transferase
IKJKALAH_00797 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IKJKALAH_00798 4.5e-111 tdk 2.7.1.21 F thymidine kinase
IKJKALAH_00799 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IKJKALAH_00800 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IKJKALAH_00801 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IKJKALAH_00802 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IKJKALAH_00803 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
IKJKALAH_00804 8e-100 pvaA M lytic transglycosylase activity
IKJKALAH_00805 0.0 yfiB1 V abc transporter atp-binding protein
IKJKALAH_00806 0.0 XK27_10035 V abc transporter atp-binding protein
IKJKALAH_00807 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
IKJKALAH_00808 1.6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKJKALAH_00809 4.6e-238 dltB M Membrane protein involved in D-alanine export
IKJKALAH_00810 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKJKALAH_00811 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IKJKALAH_00812 2.1e-238 L Transposase
IKJKALAH_00813 9.8e-32 L Integrase core domain protein
IKJKALAH_00814 9.6e-32 L transposition
IKJKALAH_00815 6.5e-54 L transposition
IKJKALAH_00816 7.7e-19 L transposase activity
IKJKALAH_00817 0.0 3.6.3.8 P cation transport ATPase
IKJKALAH_00818 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
IKJKALAH_00820 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IKJKALAH_00821 7.3e-166 metF 1.5.1.20 E reductase
IKJKALAH_00822 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IKJKALAH_00823 1.4e-93 panT S ECF transporter, substrate-specific component
IKJKALAH_00824 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IKJKALAH_00825 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
IKJKALAH_00826 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IKJKALAH_00827 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKJKALAH_00828 2.8e-40 T PhoQ Sensor
IKJKALAH_00829 1.7e-43 T PhoQ Sensor
IKJKALAH_00830 8.3e-78 T PhoQ Sensor
IKJKALAH_00831 6.7e-122 L Helix-turn-helix domain
IKJKALAH_00832 1.2e-165 L integrase core domain
IKJKALAH_00833 2.1e-30 rpsT J rRNA binding
IKJKALAH_00834 2.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
IKJKALAH_00835 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
IKJKALAH_00836 1.3e-24 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
IKJKALAH_00837 7.5e-101 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IKJKALAH_00838 5.5e-29 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IKJKALAH_00839 1.5e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IKJKALAH_00840 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IKJKALAH_00841 1.5e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IKJKALAH_00842 2.7e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IKJKALAH_00843 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
IKJKALAH_00844 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
IKJKALAH_00845 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IKJKALAH_00846 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IKJKALAH_00847 3.1e-81 ypmB S Protein conserved in bacteria
IKJKALAH_00848 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IKJKALAH_00849 4.2e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IKJKALAH_00850 2.5e-15
IKJKALAH_00851 6.8e-54 L Transposase
IKJKALAH_00852 2.7e-31 L Transposase
IKJKALAH_00853 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
IKJKALAH_00854 9.8e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IKJKALAH_00855 5.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
IKJKALAH_00856 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IKJKALAH_00857 1.9e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IKJKALAH_00858 2.2e-19 D nuclear chromosome segregation
IKJKALAH_00859 1.2e-135 yejC S cyclic nucleotide-binding protein
IKJKALAH_00860 2e-163 rapZ S Displays ATPase and GTPase activities
IKJKALAH_00861 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IKJKALAH_00862 2.5e-161 whiA K May be required for sporulation
IKJKALAH_00863 1.5e-138 pepD E Dipeptidase
IKJKALAH_00864 6.7e-40 pepD E dipeptidase activity
IKJKALAH_00865 7.4e-32 cspD K Cold shock protein domain
IKJKALAH_00866 9.4e-43 K Cold-Shock Protein
IKJKALAH_00867 8.1e-32 L Transposase
IKJKALAH_00868 1.3e-176 L Transposase
IKJKALAH_00869 0.0 copB 3.6.3.4 P P-type ATPase
IKJKALAH_00870 1.6e-88 L Transposase
IKJKALAH_00871 1.5e-93 L Transposase
IKJKALAH_00872 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IKJKALAH_00873 1.9e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IKJKALAH_00874 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IKJKALAH_00875 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
IKJKALAH_00876 6.6e-94 L Transposase
IKJKALAH_00877 4.3e-86 L Transposase
IKJKALAH_00878 8.8e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
IKJKALAH_00879 2.3e-113 hsdM 2.1.1.72 V type I restriction-modification system
IKJKALAH_00880 2.3e-151 glcU U Glucose uptake
IKJKALAH_00881 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
IKJKALAH_00882 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
IKJKALAH_00883 2.6e-86 XK27_10720 D peptidase activity
IKJKALAH_00884 5.6e-294 adcA P Belongs to the bacterial solute-binding protein 9 family
IKJKALAH_00885 5.8e-09
IKJKALAH_00886 1.2e-165 L integrase core domain
IKJKALAH_00887 2.5e-121 L Transposase
IKJKALAH_00888 1.6e-249 L Transposase
IKJKALAH_00889 1e-171 yeiH S Membrane
IKJKALAH_00890 1.6e-118 mur1 NU muramidase
IKJKALAH_00891 1.6e-19 L transposase activity
IKJKALAH_00892 4.5e-166 cpsY K Transcriptional regulator
IKJKALAH_00893 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IKJKALAH_00894 7.3e-58 phnA P Alkylphosphonate utilization operon protein PhnA
IKJKALAH_00895 4e-105 artQ P ABC transporter (Permease
IKJKALAH_00896 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKJKALAH_00897 2.1e-157 aatB ET ABC transporter substrate-binding protein
IKJKALAH_00898 2.4e-72 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKJKALAH_00899 7.3e-110 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKJKALAH_00900 2.1e-07
IKJKALAH_00901 2.3e-62 adhP 1.1.1.1 C alcohol dehydrogenase
IKJKALAH_00902 7.4e-110 adhP 1.1.1.1 C alcohol dehydrogenase
IKJKALAH_00904 1.1e-20
IKJKALAH_00905 0.0 res_1 3.1.21.5 S Type III restriction
IKJKALAH_00906 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
IKJKALAH_00907 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IKJKALAH_00908 2e-126 gntR1 K transcriptional
IKJKALAH_00909 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IKJKALAH_00910 5.2e-271 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IKJKALAH_00911 3.1e-87 niaX
IKJKALAH_00912 3e-90 niaR S small molecule binding protein (contains 3H domain)
IKJKALAH_00913 8.1e-128 K DNA-binding helix-turn-helix protein
IKJKALAH_00914 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IKJKALAH_00915 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IKJKALAH_00916 1.6e-166 GK ROK family
IKJKALAH_00917 8.3e-159 dprA LU DNA protecting protein DprA
IKJKALAH_00918 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IKJKALAH_00919 3.6e-154 S TraX protein
IKJKALAH_00920 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKJKALAH_00921 7.6e-250 T PhoQ Sensor
IKJKALAH_00922 2.1e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IKJKALAH_00923 2.7e-151 XK27_05470 E Methionine synthase
IKJKALAH_00924 7.5e-21 XK27_05470 E Methionine synthase
IKJKALAH_00925 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IKJKALAH_00926 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IKJKALAH_00927 2.2e-49 IQ Acetoin reductase
IKJKALAH_00928 3.9e-19 IQ Acetoin reductase
IKJKALAH_00929 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IKJKALAH_00930 6.7e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IKJKALAH_00933 7.2e-212 pqqE C radical SAM domain protein
IKJKALAH_00934 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
IKJKALAH_00935 8.6e-61 EGP Major facilitator Superfamily
IKJKALAH_00936 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IKJKALAH_00937 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IKJKALAH_00938 1.9e-231 L Transposase
IKJKALAH_00939 4.1e-88 V ABC transporter (Permease
IKJKALAH_00940 3e-14 V ABC transporter (Permease
IKJKALAH_00941 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IKJKALAH_00942 1.6e-10
IKJKALAH_00943 9e-98 K Transcriptional regulator, TetR family
IKJKALAH_00944 1.8e-159 czcD P cation diffusion facilitator family transporter
IKJKALAH_00945 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IKJKALAH_00946 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
IKJKALAH_00947 6e-08 S Hydrolases of the alpha beta superfamily
IKJKALAH_00948 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
IKJKALAH_00949 3.8e-78 S Alpha/beta hydrolase of unknown function (DUF915)
IKJKALAH_00952 2.6e-143 2.4.2.3 F Phosphorylase superfamily
IKJKALAH_00953 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
IKJKALAH_00954 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
IKJKALAH_00955 1.2e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
IKJKALAH_00956 8.8e-55 dinF V Mate efflux family protein
IKJKALAH_00958 2.1e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IKJKALAH_00959 1.4e-189
IKJKALAH_00960 1.7e-87 FNV0100 F Belongs to the Nudix hydrolase family
IKJKALAH_00961 3.5e-28 3.4.13.21 I Protein conserved in bacteria
IKJKALAH_00962 2.4e-234 L Transposase
IKJKALAH_00964 2e-29
IKJKALAH_00965 1.1e-12
IKJKALAH_00967 6.4e-24 L Transposase
IKJKALAH_00968 2.1e-98 S TraX protein
IKJKALAH_00969 3.2e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
IKJKALAH_00970 2.2e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IKJKALAH_00971 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IKJKALAH_00972 1.8e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IKJKALAH_00973 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IKJKALAH_00974 1.3e-131 cas6 S CRISPR-associated endoribonuclease Cas6
IKJKALAH_00975 0.0 csm1 S CRISPR-associated protein Csm1 family
IKJKALAH_00976 5.6e-62 csm2 L Pfam:DUF310
IKJKALAH_00977 1.1e-116 csm3 L RAMP superfamily
IKJKALAH_00978 1.4e-164 csm4 L CRISPR-associated RAMP protein, Csm4 family
IKJKALAH_00979 1e-193 csm5 L CRISPR-associated RAMP protein, Csm5 family
IKJKALAH_00980 2.1e-14 csm6 S Psort location Cytoplasmic, score
IKJKALAH_00981 5.2e-74 csm6 S Psort location Cytoplasmic, score
IKJKALAH_00982 2e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IKJKALAH_00983 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IKJKALAH_00984 9.3e-267 dtpT E transporter
IKJKALAH_00985 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
IKJKALAH_00986 8.2e-132 yckB ET Belongs to the bacterial solute-binding protein 3 family
IKJKALAH_00987 3.5e-68 yecS P ABC transporter (Permease
IKJKALAH_00989 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
IKJKALAH_00990 3.7e-60 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
IKJKALAH_00991 7.6e-64 yfiF3 K sequence-specific DNA binding
IKJKALAH_00992 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IKJKALAH_00993 1.8e-240 agcS E (Alanine) symporter
IKJKALAH_00994 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IKJKALAH_00995 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
IKJKALAH_00996 1.8e-59 Q phosphatase activity
IKJKALAH_00997 9.3e-62 S haloacid dehalogenase-like hydrolase
IKJKALAH_00998 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IKJKALAH_00999 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
IKJKALAH_01000 3.6e-136 XK27_04775 S hemerythrin HHE cation binding domain
IKJKALAH_01001 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
IKJKALAH_01002 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IKJKALAH_01003 2.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IKJKALAH_01004 6.1e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IKJKALAH_01005 1.9e-43 yktA S Belongs to the UPF0223 family
IKJKALAH_01006 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IKJKALAH_01007 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IKJKALAH_01008 3.3e-158 pstS P phosphate
IKJKALAH_01009 1.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
IKJKALAH_01010 3.4e-155 pstA P phosphate transport system permease
IKJKALAH_01011 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IKJKALAH_01012 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IKJKALAH_01013 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
IKJKALAH_01014 0.0 pepN 3.4.11.2 E aminopeptidase
IKJKALAH_01015 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IKJKALAH_01016 6.5e-187 lplA 6.3.1.20 H Lipoate-protein ligase
IKJKALAH_01017 1.1e-17
IKJKALAH_01018 3.7e-09
IKJKALAH_01019 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IKJKALAH_01020 1.9e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
IKJKALAH_01021 2.4e-63 malR K Transcriptional regulator
IKJKALAH_01022 4.2e-27 malR K Transcriptional regulator
IKJKALAH_01023 4.2e-17 malX G ABC transporter
IKJKALAH_01024 1.9e-93 malX G ABC transporter
IKJKALAH_01025 2.4e-111 malF P ABC transporter (Permease
IKJKALAH_01026 4.6e-25 tatA U protein secretion
IKJKALAH_01027 1.7e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IKJKALAH_01028 3e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
IKJKALAH_01029 1.5e-233 ycdB P peroxidase
IKJKALAH_01030 2.1e-152 ycdO P periplasmic lipoprotein involved in iron transport
IKJKALAH_01031 2.2e-177 fatB P ABC-type enterochelin transport system, periplasmic component
IKJKALAH_01032 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
IKJKALAH_01033 2.5e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKJKALAH_01034 4e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKJKALAH_01035 2e-139 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IKJKALAH_01036 1.1e-53 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IKJKALAH_01037 3.8e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IKJKALAH_01038 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IKJKALAH_01039 1.9e-37 3.5.1.28 NU amidase activity
IKJKALAH_01040 8.5e-266 3.5.1.28 NU amidase activity
IKJKALAH_01041 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IKJKALAH_01042 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IKJKALAH_01043 0.0 lpdA 1.8.1.4 C Dehydrogenase
IKJKALAH_01044 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IKJKALAH_01045 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IKJKALAH_01046 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IKJKALAH_01047 4.4e-66 S the current gene model (or a revised gene model) may contain a frame shift
IKJKALAH_01048 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IKJKALAH_01049 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IKJKALAH_01050 1.1e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IKJKALAH_01051 1.2e-157 rssA S Phospholipase, patatin family
IKJKALAH_01052 3.9e-78 estA E GDSL-like protein
IKJKALAH_01053 2.6e-15 estA E Lysophospholipase L1 and related esterases
IKJKALAH_01054 7.7e-291 S unusual protein kinase
IKJKALAH_01055 4.9e-39 S granule-associated protein
IKJKALAH_01056 7.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IKJKALAH_01057 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
IKJKALAH_01058 1.8e-98 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IKJKALAH_01059 1.3e-199 S hmm pf01594
IKJKALAH_01060 5.6e-101 G Belongs to the phosphoglycerate mutase family
IKJKALAH_01061 2.4e-68 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
IKJKALAH_01062 1.1e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IKJKALAH_01063 4.9e-94 V VanZ like family
IKJKALAH_01064 2.4e-37 L Transposase
IKJKALAH_01065 2.2e-17
IKJKALAH_01066 1.8e-110 L Transposase
IKJKALAH_01067 3.2e-32 cpsJ S Glycosyltransferase like family 2
IKJKALAH_01068 1.6e-16
IKJKALAH_01069 6.5e-72 M Glycosyltransferase sugar-binding region containing DXD motif
IKJKALAH_01070 1.6e-40 pssE S Glycosyltransferase family 28 C-terminal domain
IKJKALAH_01071 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
IKJKALAH_01072 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
IKJKALAH_01073 5e-38 L transposase activity
IKJKALAH_01074 1.1e-60 L Integrase core domain
IKJKALAH_01075 8.4e-72 L COG2801 Transposase and inactivated derivatives
IKJKALAH_01076 6.4e-236 cps1C S Polysaccharide biosynthesis protein
IKJKALAH_01077 1.3e-23 L Transposase
IKJKALAH_01078 3.3e-200 L Transposase
IKJKALAH_01079 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
IKJKALAH_01080 4.7e-140 L Integrase core domain
IKJKALAH_01081 2.2e-22 L Transposase
IKJKALAH_01082 5.8e-28 tnp L DDE domain
IKJKALAH_01083 9.7e-23 rgpAc GT4 M group 1 family protein
IKJKALAH_01084 1.7e-249 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IKJKALAH_01085 2.8e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
IKJKALAH_01086 1.7e-104 cps4C M biosynthesis protein
IKJKALAH_01087 2.8e-134 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
IKJKALAH_01088 5.9e-253 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
IKJKALAH_01089 3.4e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
IKJKALAH_01090 9.8e-96 yfeJ 6.3.5.2 F glutamine amidotransferase
IKJKALAH_01091 6.3e-13 yfeJ 6.3.5.2 F glutamine amidotransferase
IKJKALAH_01092 4.9e-80 clcA_2 P chloride
IKJKALAH_01093 4.4e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IKJKALAH_01094 2.3e-66 S Protein of unknown function (DUF1697)
IKJKALAH_01095 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IKJKALAH_01096 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IKJKALAH_01098 4e-21 V Glucan-binding protein C
IKJKALAH_01099 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
IKJKALAH_01100 2.4e-275 pepV 3.5.1.18 E Dipeptidase
IKJKALAH_01101 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IKJKALAH_01102 2e-41 XK27_03610 K Gnat family
IKJKALAH_01103 7.2e-83 L Transposase
IKJKALAH_01104 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IKJKALAH_01105 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IKJKALAH_01106 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IKJKALAH_01107 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IKJKALAH_01108 1.4e-22 M LysM domain
IKJKALAH_01109 8.4e-90 ebsA S Family of unknown function (DUF5322)
IKJKALAH_01110 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IKJKALAH_01111 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IKJKALAH_01112 8.3e-224 G COG0457 FOG TPR repeat
IKJKALAH_01113 4e-175 yubA S permease
IKJKALAH_01114 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
IKJKALAH_01115 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IKJKALAH_01116 2.5e-124 ftsE D cell division ATP-binding protein FtsE
IKJKALAH_01117 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IKJKALAH_01118 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IKJKALAH_01119 4.3e-180 yjjH S Calcineurin-like phosphoesterase
IKJKALAH_01120 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IKJKALAH_01121 0.0 pacL 3.6.3.8 P cation transport ATPase
IKJKALAH_01122 2.6e-67 ywiB S Domain of unknown function (DUF1934)
IKJKALAH_01123 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
IKJKALAH_01124 9.2e-147 yidA S hydrolases of the HAD superfamily
IKJKALAH_01125 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
IKJKALAH_01126 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
IKJKALAH_01127 1.5e-247 vicK 2.7.13.3 T Histidine kinase
IKJKALAH_01128 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKJKALAH_01129 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKJKALAH_01130 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IKJKALAH_01131 5.9e-118 gltJ P ABC transporter (Permease
IKJKALAH_01132 1.7e-111 tcyB_2 P ABC transporter (permease)
IKJKALAH_01133 2.4e-124 endA F DNA RNA non-specific endonuclease
IKJKALAH_01134 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
IKJKALAH_01135 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IKJKALAH_01137 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IKJKALAH_01138 5.9e-26 G Domain of unknown function (DUF4832)
IKJKALAH_01139 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IKJKALAH_01140 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IKJKALAH_01141 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IKJKALAH_01142 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
IKJKALAH_01143 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IKJKALAH_01144 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
IKJKALAH_01147 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IKJKALAH_01148 2.1e-219 XK27_05110 P chloride
IKJKALAH_01149 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
IKJKALAH_01150 1.3e-282 clcA P Chloride transporter, ClC family
IKJKALAH_01151 2.3e-75 fld C Flavodoxin
IKJKALAH_01152 5.5e-14 XK27_08880
IKJKALAH_01153 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
IKJKALAH_01154 1.6e-151 estA CE1 S Putative esterase
IKJKALAH_01155 3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IKJKALAH_01156 4.4e-135 XK27_08845 S abc transporter atp-binding protein
IKJKALAH_01157 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
IKJKALAH_01158 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
IKJKALAH_01160 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
IKJKALAH_01161 3e-25 Q the current gene model (or a revised gene model) may contain a frame shift
IKJKALAH_01162 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
IKJKALAH_01163 4.1e-220 L Transposase
IKJKALAH_01165 1.6e-249 L Transposase
IKJKALAH_01166 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IKJKALAH_01167 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IKJKALAH_01168 0.0 dnaE 2.7.7.7 L DNA polymerase
IKJKALAH_01169 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
IKJKALAH_01170 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IKJKALAH_01171 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IKJKALAH_01172 2.5e-43 ysdA L Membrane
IKJKALAH_01173 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IKJKALAH_01174 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IKJKALAH_01175 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IKJKALAH_01176 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
IKJKALAH_01178 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IKJKALAH_01179 1.7e-83 ypmS S Protein conserved in bacteria
IKJKALAH_01180 3.9e-143 ypmR E lipolytic protein G-D-S-L family
IKJKALAH_01181 1e-148 DegV S DegV family
IKJKALAH_01182 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
IKJKALAH_01183 1.8e-72 argR K Regulates arginine biosynthesis genes
IKJKALAH_01184 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IKJKALAH_01185 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IKJKALAH_01186 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
IKJKALAH_01187 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IKJKALAH_01190 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IKJKALAH_01191 2.9e-125 dnaD
IKJKALAH_01192 6e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IKJKALAH_01193 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IKJKALAH_01194 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
IKJKALAH_01195 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IKJKALAH_01196 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IKJKALAH_01197 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IKJKALAH_01198 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IKJKALAH_01199 1.6e-239 rodA D Belongs to the SEDS family
IKJKALAH_01200 4.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IKJKALAH_01201 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IKJKALAH_01202 1.9e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IKJKALAH_01203 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IKJKALAH_01204 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IKJKALAH_01205 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IKJKALAH_01206 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IKJKALAH_01207 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IKJKALAH_01208 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IKJKALAH_01209 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IKJKALAH_01211 1.4e-86 L Integrase core domain protein
IKJKALAH_01212 1.1e-53 L transposition
IKJKALAH_01213 1.8e-21 L Transposase
IKJKALAH_01214 5.2e-36 L transposase activity
IKJKALAH_01215 1.3e-22 XK27_08085
IKJKALAH_01216 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IKJKALAH_01217 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IKJKALAH_01218 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
IKJKALAH_01219 5.3e-121 ylfI S tigr01906
IKJKALAH_01220 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IKJKALAH_01221 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
IKJKALAH_01222 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
IKJKALAH_01225 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IKJKALAH_01226 2.1e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IKJKALAH_01227 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IKJKALAH_01228 1.1e-206 yurR 1.4.5.1 E oxidoreductase
IKJKALAH_01229 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
IKJKALAH_01230 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IKJKALAH_01231 8.7e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
IKJKALAH_01232 1.7e-70 gtrA S GtrA-like protein
IKJKALAH_01233 1.6e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IKJKALAH_01234 6e-169 ybbR S Protein conserved in bacteria
IKJKALAH_01235 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IKJKALAH_01236 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
IKJKALAH_01237 8.7e-150 cobQ S glutamine amidotransferase
IKJKALAH_01238 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IKJKALAH_01239 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
IKJKALAH_01240 0.0 uup S abc transporter atp-binding protein
IKJKALAH_01241 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
IKJKALAH_01242 2.5e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
IKJKALAH_01243 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IKJKALAH_01244 5.6e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
IKJKALAH_01245 2.2e-134 L Transposase
IKJKALAH_01246 3e-90 L Transposase
IKJKALAH_01247 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IKJKALAH_01248 7.9e-39 ptsH G phosphocarrier protein Hpr
IKJKALAH_01249 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
IKJKALAH_01250 4.3e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
IKJKALAH_01251 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IKJKALAH_01252 7.2e-33 nrdH O Glutaredoxin
IKJKALAH_01253 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IKJKALAH_01254 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IKJKALAH_01256 3.6e-70 L Transposase (IS116 IS110 IS902 family)
IKJKALAH_01257 8.8e-60 L Transposase (IS116 IS110 IS902 family)
IKJKALAH_01258 9e-165 ypuA S secreted protein
IKJKALAH_01259 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
IKJKALAH_01260 2.6e-122 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
IKJKALAH_01261 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IKJKALAH_01262 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IKJKALAH_01263 3.4e-258 noxE P NADH oxidase
IKJKALAH_01264 1.9e-294 yfmM S abc transporter atp-binding protein
IKJKALAH_01265 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
IKJKALAH_01266 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IKJKALAH_01267 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IKJKALAH_01268 2e-86 S ECF-type riboflavin transporter, S component
IKJKALAH_01270 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKJKALAH_01271 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
IKJKALAH_01273 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IKJKALAH_01274 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKJKALAH_01275 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IKJKALAH_01276 0.0 smc D Required for chromosome condensation and partitioning
IKJKALAH_01277 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IKJKALAH_01278 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IKJKALAH_01279 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IKJKALAH_01280 2.4e-92 pat 2.3.1.183 M acetyltransferase
IKJKALAH_01281 3e-13
IKJKALAH_01282 6.3e-23
IKJKALAH_01283 4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IKJKALAH_01284 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IKJKALAH_01285 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
IKJKALAH_01286 3.5e-76 L Integrase
IKJKALAH_01287 5.6e-56 L Integrase core domain
IKJKALAH_01288 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
IKJKALAH_01289 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
IKJKALAH_01290 7.4e-26
IKJKALAH_01291 1.1e-144 S ABC-2 family transporter protein
IKJKALAH_01292 3.5e-33 S transport system, permease component
IKJKALAH_01293 3.6e-97 S transport system, permease component
IKJKALAH_01294 9.2e-81 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKJKALAH_01295 1.5e-192 desK 2.7.13.3 T Histidine kinase
IKJKALAH_01296 1.4e-133 yvfS V ABC-2 type transporter
IKJKALAH_01297 8.7e-159 XK27_09825 V abc transporter atp-binding protein
IKJKALAH_01301 6.6e-213 EGP Major facilitator Superfamily
IKJKALAH_01302 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
IKJKALAH_01303 6e-152 mutR K Transcriptional activator, Rgg GadR MutR family
IKJKALAH_01304 4.6e-42 3.6.1.55 F NUDIX domain
IKJKALAH_01305 3.9e-223 L Transposase
IKJKALAH_01307 3.7e-122 S An automated process has identified a potential problem with this gene model
IKJKALAH_01308 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
IKJKALAH_01309 1.4e-15 liaI KT membrane
IKJKALAH_01310 2.6e-30 liaI KT membrane
IKJKALAH_01311 6.1e-93 XK27_05000 S metal cluster binding
IKJKALAH_01312 0.0 V ABC transporter (permease)
IKJKALAH_01313 3.2e-133 macB2 V ABC transporter, ATP-binding protein
IKJKALAH_01314 6.2e-166 T Histidine kinase
IKJKALAH_01315 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKJKALAH_01316 3.2e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IKJKALAH_01318 1.2e-198 pbuX F xanthine permease
IKJKALAH_01319 3.4e-247 norM V Multidrug efflux pump
IKJKALAH_01320 6.3e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IKJKALAH_01321 3.5e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
IKJKALAH_01322 2.9e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
IKJKALAH_01323 7.3e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
IKJKALAH_01324 4.1e-63 yxeN U ABC transporter, permease protein
IKJKALAH_01325 4.1e-58 yxeL K Acetyltransferase (GNAT) domain
IKJKALAH_01326 3e-115 yxeQ S MmgE/PrpD family
IKJKALAH_01327 5.6e-145 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
IKJKALAH_01328 1.5e-78 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
IKJKALAH_01329 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
IKJKALAH_01330 6.7e-35 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IKJKALAH_01331 6.7e-129 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IKJKALAH_01332 5.6e-234 brnQ E Component of the transport system for branched-chain amino acids
IKJKALAH_01333 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
IKJKALAH_01334 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
IKJKALAH_01335 9.6e-26 csbD K CsbD-like
IKJKALAH_01337 6.2e-228 yfnA E amino acid
IKJKALAH_01338 4.9e-228 S dextransucrase activity
IKJKALAH_01339 1.1e-139 S dextransucrase activity
IKJKALAH_01340 1.6e-21 L Integrase core domain protein
IKJKALAH_01343 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
IKJKALAH_01344 3e-114 yxeN P ABC transporter, permease protein
IKJKALAH_01345 6.1e-107 ytmL P ABC transporter (Permease
IKJKALAH_01346 1.8e-161 ET ABC transporter substrate-binding protein
IKJKALAH_01347 8.1e-161 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
IKJKALAH_01348 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IKJKALAH_01349 2.4e-40 S Sugar efflux transporter for intercellular exchange
IKJKALAH_01350 5.9e-23 P FtsX-like permease family
IKJKALAH_01351 3.2e-91 V abc transporter atp-binding protein
IKJKALAH_01352 3.9e-82 K WHG domain
IKJKALAH_01353 1.1e-59 ydhF S Aldo keto reductase
IKJKALAH_01354 2.1e-71 ydhF S Aldo keto reductase
IKJKALAH_01356 5.1e-110 XK27_02070 S nitroreductase
IKJKALAH_01357 9.5e-150 1.13.11.2 S glyoxalase
IKJKALAH_01358 4.7e-76 ywnA K Transcriptional regulator
IKJKALAH_01359 8.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
IKJKALAH_01360 5.6e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IKJKALAH_01361 1.4e-110 drgA C Nitroreductase
IKJKALAH_01362 3e-102 yoaK S Protein of unknown function (DUF1275)
IKJKALAH_01364 6.8e-161 yvgN C reductase
IKJKALAH_01365 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IKJKALAH_01366 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
IKJKALAH_01368 1.1e-37 BP1961 P nitric oxide dioxygenase activity
IKJKALAH_01369 1.4e-54 K response regulator
IKJKALAH_01370 9.3e-72 S Signal peptide protein, YSIRK family
IKJKALAH_01371 4.5e-61
IKJKALAH_01372 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKJKALAH_01373 1e-137
IKJKALAH_01374 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
IKJKALAH_01375 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
IKJKALAH_01376 5.8e-109 MA20_06410 E LysE type translocator
IKJKALAH_01377 5.6e-08
IKJKALAH_01378 2.7e-09
IKJKALAH_01379 0.0 M family 8
IKJKALAH_01381 1.5e-162 hrtB V MacB-like periplasmic core domain
IKJKALAH_01382 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
IKJKALAH_01383 1.1e-151 V MatE
IKJKALAH_01385 3.9e-110 C Fe-S oxidoreductases
IKJKALAH_01386 1.2e-176 EGP Major Facilitator Superfamily
IKJKALAH_01387 1.6e-257 I radical SAM domain protein
IKJKALAH_01389 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IKJKALAH_01390 1.4e-150 L Integrase core domain protein
IKJKALAH_01391 1.8e-87 L transposase activity
IKJKALAH_01393 2.8e-85
IKJKALAH_01394 0.0 sbcC L ATPase involved in DNA repair
IKJKALAH_01395 1.2e-112 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IKJKALAH_01396 3e-107 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IKJKALAH_01397 0.0 lacL 3.2.1.23 G -beta-galactosidase
IKJKALAH_01398 0.0 lacS G transporter
IKJKALAH_01399 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IKJKALAH_01400 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IKJKALAH_01401 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IKJKALAH_01402 8.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IKJKALAH_01403 2.3e-184 galR K Transcriptional regulator
IKJKALAH_01404 2.7e-08 L Integrase core domain protein
IKJKALAH_01405 1.2e-25 L transposition
IKJKALAH_01406 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IKJKALAH_01407 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IKJKALAH_01408 2.5e-101 V abc transporter atp-binding protein
IKJKALAH_01409 4.3e-40 V abc transporter atp-binding protein
IKJKALAH_01410 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
IKJKALAH_01411 6.4e-62 L Transposase
IKJKALAH_01412 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IKJKALAH_01413 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IKJKALAH_01414 7e-119 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IKJKALAH_01415 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IKJKALAH_01416 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IKJKALAH_01417 2.1e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IKJKALAH_01418 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IKJKALAH_01421 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKJKALAH_01422 5.8e-175 vraS 2.7.13.3 T Histidine kinase
IKJKALAH_01423 3.7e-120 yvqF KT membrane
IKJKALAH_01424 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IKJKALAH_01425 2e-132 stp 3.1.3.16 T phosphatase
IKJKALAH_01426 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IKJKALAH_01427 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IKJKALAH_01428 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IKJKALAH_01429 1.4e-45 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
IKJKALAH_01430 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IKJKALAH_01431 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IKJKALAH_01432 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
IKJKALAH_01433 8.5e-145 supH S overlaps another CDS with the same product name
IKJKALAH_01434 8.6e-63 yvoA_1 K Transcriptional
IKJKALAH_01435 1.1e-119 skfE V abc transporter atp-binding protein
IKJKALAH_01436 3.3e-133 V ATPase activity
IKJKALAH_01437 4.3e-172 oppF P Belongs to the ABC transporter superfamily
IKJKALAH_01438 2.2e-204 oppD P Belongs to the ABC transporter superfamily
IKJKALAH_01439 4.9e-168 amiD P ABC transporter (Permease
IKJKALAH_01440 2.1e-277 amiC P ABC transporter (Permease
IKJKALAH_01441 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IKJKALAH_01442 1e-223 L Transposase
IKJKALAH_01443 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IKJKALAH_01444 8.1e-45 L Transposase
IKJKALAH_01445 4.1e-158 L COG2801 Transposase and inactivated derivatives
IKJKALAH_01446 1.2e-24 oppF P Belongs to the ABC transporter superfamily
IKJKALAH_01447 3.8e-45 oppF P Belongs to the ABC transporter superfamily
IKJKALAH_01448 1.4e-40 tatD L Hydrolase, tatd
IKJKALAH_01449 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
IKJKALAH_01450 1e-110 L Integrase core domain protein
IKJKALAH_01451 1.1e-23 L transposase activity
IKJKALAH_01452 8.9e-18 L transposase activity
IKJKALAH_01453 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IKJKALAH_01454 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IKJKALAH_01455 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IKJKALAH_01456 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
IKJKALAH_01457 1.5e-103 yjbK S Adenylate cyclase
IKJKALAH_01458 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IKJKALAH_01459 1.2e-205 iscS 2.8.1.7 E Cysteine desulfurase
IKJKALAH_01460 9e-59 XK27_04120 S Putative amino acid metabolism
IKJKALAH_01461 3.5e-238 L Transposase
IKJKALAH_01462 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IKJKALAH_01463 7.2e-132 puuD T peptidase C26
IKJKALAH_01464 2.4e-119 radC E Belongs to the UPF0758 family
IKJKALAH_01465 0.0 rgpF M Rhamnan synthesis protein F
IKJKALAH_01466 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IKJKALAH_01467 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IKJKALAH_01468 2.8e-143 rgpC GM Transport permease protein
IKJKALAH_01469 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
IKJKALAH_01470 1.3e-226 rgpA GT4 M Domain of unknown function (DUF1972)
IKJKALAH_01471 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
IKJKALAH_01472 2.6e-220 amrA S polysaccharide biosynthetic process
IKJKALAH_01473 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
IKJKALAH_01474 7.6e-126 ycbB S Glycosyl transferase family 2
IKJKALAH_01475 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IKJKALAH_01476 3.2e-245
IKJKALAH_01477 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
IKJKALAH_01478 1.4e-251 M Psort location CytoplasmicMembrane, score
IKJKALAH_01479 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
IKJKALAH_01480 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IKJKALAH_01481 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IKJKALAH_01482 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IKJKALAH_01483 1.5e-124 gltS ET Belongs to the bacterial solute-binding protein 3 family
IKJKALAH_01484 2.1e-202 arcT 2.6.1.1 E Aminotransferase
IKJKALAH_01485 9.4e-136 ET ABC transporter
IKJKALAH_01486 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
IKJKALAH_01487 2.9e-84 mutT 3.6.1.55 F Nudix family
IKJKALAH_01488 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IKJKALAH_01490 4.3e-82 S CAAX amino terminal protease family protein
IKJKALAH_01491 2.4e-33 S CAAX amino terminal protease family protein
IKJKALAH_01492 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
IKJKALAH_01493 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKJKALAH_01494 1.1e-16 XK27_00735
IKJKALAH_01495 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IKJKALAH_01497 3.6e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IKJKALAH_01500 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
IKJKALAH_01501 6.6e-30 ycaO O OsmC-like protein
IKJKALAH_01503 8.5e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
IKJKALAH_01505 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
IKJKALAH_01506 1.4e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IKJKALAH_01507 7.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IKJKALAH_01508 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IKJKALAH_01509 9.3e-239 L Transposase
IKJKALAH_01510 2e-115 serB 3.1.3.3 E phosphoserine phosphatase
IKJKALAH_01511 3e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IKJKALAH_01512 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IKJKALAH_01513 2.6e-109 3.1.3.18 S IA, variant 1
IKJKALAH_01514 2.2e-117 lrgB M effector of murein hydrolase
IKJKALAH_01515 2.2e-58 lrgA S Effector of murein hydrolase LrgA
IKJKALAH_01517 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
IKJKALAH_01518 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
IKJKALAH_01519 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IKJKALAH_01520 3.9e-104 wecD M Acetyltransferase GNAT family
IKJKALAH_01521 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IKJKALAH_01522 5.5e-46 GK ROK family
IKJKALAH_01523 3.7e-62 GK ROK family
IKJKALAH_01524 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
IKJKALAH_01525 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
IKJKALAH_01526 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
IKJKALAH_01527 2.3e-206 potD P spermidine putrescine ABC transporter
IKJKALAH_01528 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
IKJKALAH_01529 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
IKJKALAH_01530 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IKJKALAH_01531 7.8e-171 murB 1.3.1.98 M cell wall formation
IKJKALAH_01532 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IKJKALAH_01533 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IKJKALAH_01534 3.5e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
IKJKALAH_01535 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IKJKALAH_01536 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
IKJKALAH_01537 0.0 ydaO E amino acid
IKJKALAH_01538 1.6e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IKJKALAH_01539 4.1e-37 ylqC L Belongs to the UPF0109 family
IKJKALAH_01540 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IKJKALAH_01541 2e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
IKJKALAH_01542 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
IKJKALAH_01543 2.1e-74 S QueT transporter
IKJKALAH_01544 1.9e-55 L Transposase
IKJKALAH_01545 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IKJKALAH_01546 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IKJKALAH_01547 3.7e-85 ccl S cog cog4708
IKJKALAH_01548 7.4e-164 rbn E Belongs to the UPF0761 family
IKJKALAH_01549 2.1e-165 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IKJKALAH_01550 3.6e-230 ytoI K transcriptional regulator containing CBS domains
IKJKALAH_01551 7e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
IKJKALAH_01552 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IKJKALAH_01553 0.0 comEC S Competence protein ComEC
IKJKALAH_01554 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IKJKALAH_01555 1.3e-142 plsC 2.3.1.51 I Acyltransferase
IKJKALAH_01556 1.7e-77 nodB3 G polysaccharide deacetylase
IKJKALAH_01557 4.1e-22 nodB3 G polysaccharide deacetylase
IKJKALAH_01558 2.3e-139 yabB 2.1.1.223 L Methyltransferase
IKJKALAH_01559 1e-41 yazA L endonuclease containing a URI domain
IKJKALAH_01560 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IKJKALAH_01561 2.3e-154 corA P CorA-like protein
IKJKALAH_01562 1.9e-62 yjqA S Bacterial PH domain
IKJKALAH_01563 7.8e-100 thiT S Thiamine transporter
IKJKALAH_01564 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IKJKALAH_01565 1.9e-201 yjbB G Permeases of the major facilitator superfamily
IKJKALAH_01566 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IKJKALAH_01567 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
IKJKALAH_01568 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IKJKALAH_01572 1.1e-155 cjaA ET ABC transporter substrate-binding protein
IKJKALAH_01573 7.6e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
IKJKALAH_01574 3e-106 P ABC transporter (Permease
IKJKALAH_01575 6e-115 papP P ABC transporter (Permease
IKJKALAH_01576 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IKJKALAH_01577 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
IKJKALAH_01578 0.0 copA 3.6.3.54 P P-type ATPase
IKJKALAH_01579 2.7e-73 copY K Copper transport repressor, CopY TcrY family
IKJKALAH_01580 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IKJKALAH_01581 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IKJKALAH_01582 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
IKJKALAH_01583 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IKJKALAH_01584 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IKJKALAH_01585 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
IKJKALAH_01586 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IKJKALAH_01587 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
IKJKALAH_01588 5.4e-53
IKJKALAH_01589 0.0 ctpE P E1-E2 ATPase
IKJKALAH_01590 3.9e-26
IKJKALAH_01591 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IKJKALAH_01592 9.7e-28 L transposase activity
IKJKALAH_01593 2.7e-129 K transcriptional regulator, MerR family
IKJKALAH_01594 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
IKJKALAH_01595 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
IKJKALAH_01596 7.4e-64 XK27_02560 S cog cog2151
IKJKALAH_01597 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IKJKALAH_01598 7.7e-227 ytfP S Flavoprotein
IKJKALAH_01600 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IKJKALAH_01601 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
IKJKALAH_01602 2.7e-183 ecsB U ABC transporter
IKJKALAH_01603 2.3e-133 ecsA V abc transporter atp-binding protein
IKJKALAH_01604 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IKJKALAH_01605 5.6e-12
IKJKALAH_01606 2.6e-55 S CD20-like family
IKJKALAH_01607 7.3e-107
IKJKALAH_01609 8.8e-223 L Transposase
IKJKALAH_01610 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
IKJKALAH_01611 6.9e-206 ylbM S Belongs to the UPF0348 family
IKJKALAH_01612 2e-140 yqeM Q Methyltransferase domain protein
IKJKALAH_01613 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IKJKALAH_01614 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IKJKALAH_01615 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IKJKALAH_01616 3.5e-49 yhbY J RNA-binding protein
IKJKALAH_01617 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IKJKALAH_01618 1.8e-98 yqeG S hydrolase of the HAD superfamily
IKJKALAH_01619 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IKJKALAH_01620 1.2e-58
IKJKALAH_01621 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IKJKALAH_01622 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IKJKALAH_01623 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IKJKALAH_01624 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IKJKALAH_01625 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IKJKALAH_01626 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IKJKALAH_01627 1.5e-124 hlpA M Belongs to the NlpA lipoprotein family
IKJKALAH_01628 6.8e-101 pncA Q isochorismatase
IKJKALAH_01629 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IKJKALAH_01630 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
IKJKALAH_01631 2.4e-75 XK27_03180 T universal stress protein
IKJKALAH_01634 6.3e-156 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IKJKALAH_01635 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
IKJKALAH_01636 1.2e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
IKJKALAH_01637 0.0 yjcE P NhaP-type Na H and K H antiporters
IKJKALAH_01639 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
IKJKALAH_01640 3.8e-184 yhcC S radical SAM protein
IKJKALAH_01641 2.2e-196 ylbL T Belongs to the peptidase S16 family
IKJKALAH_01642 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IKJKALAH_01643 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
IKJKALAH_01644 3.2e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IKJKALAH_01645 1.9e-09 S Protein of unknown function (DUF4059)
IKJKALAH_01646 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
IKJKALAH_01647 1e-162 yxeN P ABC transporter (Permease
IKJKALAH_01648 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IKJKALAH_01650 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKJKALAH_01651 0.0 pflB 2.3.1.54 C formate acetyltransferase'
IKJKALAH_01652 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
IKJKALAH_01653 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKJKALAH_01654 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
IKJKALAH_01655 2.9e-87 D nuclear chromosome segregation
IKJKALAH_01656 1.5e-127 ybbM S transport system, permease component
IKJKALAH_01657 1.2e-117 ybbL S abc transporter atp-binding protein
IKJKALAH_01658 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
IKJKALAH_01659 4.6e-140 cppA E CppA N-terminal
IKJKALAH_01660 5e-44 V CAAX protease self-immunity
IKJKALAH_01661 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
IKJKALAH_01662 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IKJKALAH_01665 3e-47 spiA K sequence-specific DNA binding
IKJKALAH_01666 2.9e-28 blpT
IKJKALAH_01667 6.7e-98 blpT
IKJKALAH_01668 3.9e-122 L Transposase
IKJKALAH_01669 2.5e-161 L integrase core domain
IKJKALAH_01674 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
IKJKALAH_01677 7.4e-135 agrA KT phosphorelay signal transduction system
IKJKALAH_01678 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
IKJKALAH_01680 7.3e-237 mesE M Transport protein ComB
IKJKALAH_01681 9.3e-281 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IKJKALAH_01682 2.8e-108 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IKJKALAH_01683 0.0 mdlB V abc transporter atp-binding protein
IKJKALAH_01684 0.0 mdlA V abc transporter atp-binding protein
IKJKALAH_01686 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
IKJKALAH_01687 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IKJKALAH_01688 2.3e-72 yutD J protein conserved in bacteria
IKJKALAH_01689 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IKJKALAH_01691 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IKJKALAH_01692 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IKJKALAH_01693 0.0 ftsI 3.4.16.4 M penicillin-binding protein
IKJKALAH_01694 8.1e-46 ftsL D cell division protein FtsL
IKJKALAH_01695 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IKJKALAH_01696 3e-128
IKJKALAH_01697 9.7e-32 yhaI J Protein of unknown function (DUF805)
IKJKALAH_01698 1.3e-08 D nuclear chromosome segregation
IKJKALAH_01699 4.5e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IKJKALAH_01700 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IKJKALAH_01701 2.2e-285 XK27_00765
IKJKALAH_01702 8.1e-134 ecsA_2 V abc transporter atp-binding protein
IKJKALAH_01703 5.2e-125 S Protein of unknown function (DUF554)
IKJKALAH_01704 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IKJKALAH_01705 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IKJKALAH_01706 9.8e-57 liaI S membrane
IKJKALAH_01707 7e-10 XK27_02470 K LytTr DNA-binding domain protein
IKJKALAH_01708 1.8e-65 KT response to antibiotic
IKJKALAH_01709 5.2e-81 yebC M Membrane
IKJKALAH_01710 2.9e-18 yebC M Membrane
IKJKALAH_01711 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
IKJKALAH_01712 1.8e-181 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IKJKALAH_01713 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IKJKALAH_01714 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IKJKALAH_01715 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IKJKALAH_01716 7.2e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IKJKALAH_01717 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IKJKALAH_01718 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IKJKALAH_01720 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
IKJKALAH_01721 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
IKJKALAH_01722 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
IKJKALAH_01723 5.4e-291 scrB 3.2.1.26 GH32 G invertase
IKJKALAH_01724 7.5e-180 scrR K Transcriptional
IKJKALAH_01725 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IKJKALAH_01726 3.4e-62 yqhY S protein conserved in bacteria
IKJKALAH_01727 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IKJKALAH_01728 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
IKJKALAH_01729 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
IKJKALAH_01731 8e-44 V 'abc transporter, ATP-binding protein
IKJKALAH_01732 1e-58 V 'abc transporter, ATP-binding protein
IKJKALAH_01735 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IKJKALAH_01736 2e-169 corA P COG0598 Mg2 and Co2 transporters
IKJKALAH_01737 3.1e-124 XK27_01040 S Pfam PF06570
IKJKALAH_01739 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IKJKALAH_01740 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IKJKALAH_01741 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
IKJKALAH_01742 9.5e-42 XK27_05745
IKJKALAH_01743 6.1e-229 mutY L A G-specific adenine glycosylase
IKJKALAH_01749 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IKJKALAH_01750 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IKJKALAH_01751 1e-93 cvpA S toxin biosynthetic process
IKJKALAH_01752 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IKJKALAH_01753 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IKJKALAH_01754 1.8e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IKJKALAH_01755 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IKJKALAH_01756 2e-47 azlD E branched-chain amino acid
IKJKALAH_01757 1.8e-114 azlC E AzlC protein
IKJKALAH_01758 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IKJKALAH_01759 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IKJKALAH_01760 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
IKJKALAH_01761 2.5e-33 ykzG S Belongs to the UPF0356 family
IKJKALAH_01762 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IKJKALAH_01763 2.7e-40 pscB M CHAP domain protein
IKJKALAH_01764 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
IKJKALAH_01765 8.5e-63 glnR K Transcriptional regulator
IKJKALAH_01766 1.3e-87 S Fusaric acid resistance protein-like
IKJKALAH_01767 1.1e-12
IKJKALAH_01768 8.9e-30
IKJKALAH_01769 4.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IKJKALAH_01770 3.2e-42 L Transposase
IKJKALAH_01771 1.9e-46 L transposase activity
IKJKALAH_01772 7.4e-23 L Transposase
IKJKALAH_01773 1.8e-56 L transposition
IKJKALAH_01774 9.1e-83 L Integrase core domain protein
IKJKALAH_01775 1e-102 L Transposase
IKJKALAH_01776 6.1e-114 L Transposase
IKJKALAH_01777 9.3e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IKJKALAH_01778 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IKJKALAH_01779 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IKJKALAH_01780 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IKJKALAH_01781 1.1e-142 purR 2.4.2.7 F operon repressor
IKJKALAH_01782 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
IKJKALAH_01783 6.9e-173 rmuC S RmuC domain protein
IKJKALAH_01784 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
IKJKALAH_01785 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IKJKALAH_01786 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IKJKALAH_01788 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IKJKALAH_01789 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IKJKALAH_01790 4.1e-144 tatD L Hydrolase, tatd
IKJKALAH_01791 2.5e-74 yccU S CoA-binding protein
IKJKALAH_01792 4.8e-51 trxA O Belongs to the thioredoxin family
IKJKALAH_01793 2.4e-170 L Integrase
IKJKALAH_01794 6.6e-142 S Macro domain protein
IKJKALAH_01795 2e-09 L thioesterase
IKJKALAH_01796 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
IKJKALAH_01800 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IKJKALAH_01801 5e-84 L Transposase
IKJKALAH_01802 1e-13 rpmH J Ribosomal protein L34
IKJKALAH_01803 5.5e-184 jag S RNA-binding protein
IKJKALAH_01804 1.5e-07 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IKJKALAH_01805 2.4e-170 L Integrase
IKJKALAH_01806 2.8e-124 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IKJKALAH_01807 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IKJKALAH_01808 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
IKJKALAH_01809 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IKJKALAH_01810 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IKJKALAH_01811 2.2e-79 amiA E transmembrane transport
IKJKALAH_01812 4.2e-74 amiA E transmembrane transport
IKJKALAH_01813 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IKJKALAH_01814 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IKJKALAH_01815 3.5e-50 S Protein of unknown function (DUF3397)
IKJKALAH_01816 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
IKJKALAH_01817 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
IKJKALAH_01818 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
IKJKALAH_01819 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IKJKALAH_01820 5.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IKJKALAH_01821 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
IKJKALAH_01822 6.2e-76 XK27_09620 S reductase
IKJKALAH_01823 4.7e-213 XK27_09615 C reductase
IKJKALAH_01824 2.1e-115 fnt P Formate nitrite transporter
IKJKALAH_01825 1.2e-23 XK27_08585 S Psort location CytoplasmicMembrane, score
IKJKALAH_01826 2.2e-27 XK27_08585 S Psort location CytoplasmicMembrane, score
IKJKALAH_01827 7.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IKJKALAH_01828 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IKJKALAH_01829 1.2e-165 L integrase core domain
IKJKALAH_01830 1.1e-121 L Transposase
IKJKALAH_01831 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IKJKALAH_01832 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IKJKALAH_01833 1.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IKJKALAH_01834 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IKJKALAH_01835 2.7e-48 S glycolate biosynthetic process
IKJKALAH_01836 3.4e-64 S phosphatase activity
IKJKALAH_01837 1.3e-156 rrmA 2.1.1.187 Q methyltransferase
IKJKALAH_01839 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IKJKALAH_01840 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IKJKALAH_01841 6.4e-37 yeeD O sulfur carrier activity
IKJKALAH_01842 1.8e-187 yeeE S Sulphur transport
IKJKALAH_01843 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IKJKALAH_01844 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IKJKALAH_01845 4.1e-09 S Domain of unknown function (DUF4651)
IKJKALAH_01846 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IKJKALAH_01847 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IKJKALAH_01848 1.8e-111 S CAAX amino terminal protease family protein
IKJKALAH_01850 5e-67 V CAAX protease self-immunity
IKJKALAH_01851 1.4e-33 V CAAX protease self-immunity
IKJKALAH_01852 8.8e-27 lanR K sequence-specific DNA binding
IKJKALAH_01853 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IKJKALAH_01854 5.9e-177 ytxK 2.1.1.72 L DNA methylase
IKJKALAH_01855 6.8e-13 comGF U Putative Competence protein ComGF
IKJKALAH_01856 4e-72 comGF U Competence protein ComGF
IKJKALAH_01857 1.4e-15 NU Type II secretory pathway pseudopilin
IKJKALAH_01858 1.8e-57 cglD NU Competence protein
IKJKALAH_01859 8.5e-43 comGC U Required for transformation and DNA binding
IKJKALAH_01860 9.2e-153 cglB NU type II secretion system
IKJKALAH_01861 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IKJKALAH_01862 2.9e-68 S cog cog4699
IKJKALAH_01863 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKJKALAH_01864 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKJKALAH_01865 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IKJKALAH_01866 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IKJKALAH_01867 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IKJKALAH_01868 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
IKJKALAH_01869 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
IKJKALAH_01870 3.1e-08 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IKJKALAH_01871 2.6e-277 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IKJKALAH_01872 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IKJKALAH_01873 6.4e-304 yloV S kinase related to dihydroxyacetone kinase
IKJKALAH_01874 1.4e-57 asp S cog cog1302
IKJKALAH_01875 9.3e-226 norN V Mate efflux family protein
IKJKALAH_01876 8.3e-279 thrC 4.2.3.1 E Threonine synthase
IKJKALAH_01877 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IKJKALAH_01878 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
IKJKALAH_01879 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IKJKALAH_01880 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IKJKALAH_01881 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
IKJKALAH_01882 0.0 pepO 3.4.24.71 O Peptidase family M13
IKJKALAH_01883 1.8e-37 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IKJKALAH_01884 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IKJKALAH_01885 2.3e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IKJKALAH_01886 1.4e-54 treB 2.7.1.201 G PTS System
IKJKALAH_01887 5.8e-21 treR K DNA-binding transcription factor activity
IKJKALAH_01888 1.2e-85 treR K trehalose operon
IKJKALAH_01889 3.3e-95 ywlG S Belongs to the UPF0340 family
IKJKALAH_01892 2e-35 L PFAM Integrase, catalytic core
IKJKALAH_01893 2e-94 L PFAM Integrase, catalytic core
IKJKALAH_01894 2.5e-29 K Putative DNA-binding domain
IKJKALAH_01895 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
IKJKALAH_01896 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IKJKALAH_01897 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
IKJKALAH_01902 1e-39
IKJKALAH_01903 6.5e-31
IKJKALAH_01904 5e-31 S Hypothetical protein (DUF2513)
IKJKALAH_01905 7.7e-13
IKJKALAH_01907 5.7e-217 S MvaI/BcnI restriction endonuclease family
IKJKALAH_01909 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
IKJKALAH_01910 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
IKJKALAH_01912 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
IKJKALAH_01913 8.1e-64 6.3.2.2 H gamma-glutamylcysteine synthetase
IKJKALAH_01914 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
IKJKALAH_01915 3.3e-09 L PFAM Integrase, catalytic core
IKJKALAH_01916 1.8e-111 L PFAM Integrase, catalytic core
IKJKALAH_01917 3.3e-62 rplQ J ribosomal protein l17
IKJKALAH_01918 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKJKALAH_01919 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IKJKALAH_01920 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IKJKALAH_01921 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IKJKALAH_01922 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IKJKALAH_01923 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IKJKALAH_01924 1.4e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IKJKALAH_01925 4.4e-58 rplO J binds to the 23S rRNA
IKJKALAH_01926 2.5e-23 rpmD J ribosomal protein l30
IKJKALAH_01927 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IKJKALAH_01928 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IKJKALAH_01929 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IKJKALAH_01930 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IKJKALAH_01931 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IKJKALAH_01932 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IKJKALAH_01933 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IKJKALAH_01934 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IKJKALAH_01935 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IKJKALAH_01936 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
IKJKALAH_01937 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IKJKALAH_01938 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IKJKALAH_01939 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IKJKALAH_01940 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IKJKALAH_01941 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IKJKALAH_01942 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IKJKALAH_01943 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
IKJKALAH_01944 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IKJKALAH_01945 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
IKJKALAH_01946 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IKJKALAH_01947 0.0 XK27_09800 I Acyltransferase
IKJKALAH_01948 1.7e-35 XK27_09805 S MORN repeat protein
IKJKALAH_01949 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IKJKALAH_01950 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IKJKALAH_01951 3.3e-136 L Integrase
IKJKALAH_01952 6.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKJKALAH_01953 3.7e-29 S Domain of unknown function (DUF4649)
IKJKALAH_01954 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IKJKALAH_01955 3.2e-56 Z012_04635 K sequence-specific DNA binding
IKJKALAH_01956 1.4e-59 Z012_04635 K sequence-specific DNA binding
IKJKALAH_01958 3.6e-61 C Radical SAM
IKJKALAH_01959 6.3e-159 C Radical SAM
IKJKALAH_01960 1.1e-286 V ABC transporter transmembrane region
IKJKALAH_01961 2.5e-89 K sequence-specific DNA binding
IKJKALAH_01962 2.2e-132 int L Belongs to the 'phage' integrase family
IKJKALAH_01964 2.2e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
IKJKALAH_01965 5.5e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IKJKALAH_01966 2.2e-44 yrzL S Belongs to the UPF0297 family
IKJKALAH_01967 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IKJKALAH_01968 4.2e-44 yrzB S Belongs to the UPF0473 family
IKJKALAH_01969 6.1e-126 ccs S the current gene model (or a revised gene model) may contain a frame shift
IKJKALAH_01970 2.3e-162 ccs S the current gene model (or a revised gene model) may contain a frame shift
IKJKALAH_01971 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IKJKALAH_01972 7.5e-14
IKJKALAH_01973 1.7e-90 XK27_10930 K acetyltransferase
IKJKALAH_01974 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IKJKALAH_01975 7e-147 yaaA S Belongs to the UPF0246 family
IKJKALAH_01976 9.3e-167 XK27_01785 S cog cog1284
IKJKALAH_01977 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IKJKALAH_01979 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
IKJKALAH_01980 1.4e-53 metE 2.1.1.14 E Methionine synthase
IKJKALAH_01981 5.2e-55 metE 2.1.1.14 E Methionine synthase
IKJKALAH_01982 1.4e-36 metE 2.1.1.14 E Methionine synthase
IKJKALAH_01983 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IKJKALAH_01984 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IKJKALAH_01985 1.1e-236 L Helix-turn-helix domain of transposase family ISL3
IKJKALAH_01986 8e-191 L DNA restriction-modification system
IKJKALAH_01987 4.6e-64 V Restriction endonuclease
IKJKALAH_01988 7.4e-87 2.7.11.1 K nucleotide-binding Protein
IKJKALAH_01989 2.7e-120
IKJKALAH_01990 1.9e-30
IKJKALAH_01991 6.8e-45
IKJKALAH_01992 7.4e-184 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IKJKALAH_01993 3e-41
IKJKALAH_01994 2.8e-111 S Plasmid replication protein
IKJKALAH_01995 1.4e-21 S MerR HTH family regulatory protein
IKJKALAH_01996 1.4e-221 sip L Belongs to the 'phage' integrase family
IKJKALAH_01999 1.5e-49 yegS 2.7.1.107 I lipid kinase activity
IKJKALAH_02000 2.5e-96 S Hydrophobic domain protein
IKJKALAH_02002 1e-29 S Membrane
IKJKALAH_02003 9.1e-101
IKJKALAH_02004 1.8e-23 S Small integral membrane protein
IKJKALAH_02005 3.1e-85 M Protein conserved in bacteria
IKJKALAH_02006 1.1e-11 K CsbD-like
IKJKALAH_02007 3.4e-13 nudL L hydrolase
IKJKALAH_02008 4e-19 K negative regulation of transcription, DNA-templated
IKJKALAH_02009 1.7e-23 K negative regulation of transcription, DNA-templated
IKJKALAH_02011 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
IKJKALAH_02012 1.8e-88 S Putative adhesin
IKJKALAH_02013 3.9e-161 XK27_06930 V domain protein
IKJKALAH_02014 6.4e-96 XK27_06935 K transcriptional regulator
IKJKALAH_02015 2e-53 ypaA S membrane
IKJKALAH_02018 4.4e-18 yjgN S membrane
IKJKALAH_02019 2.8e-27 S Transcriptional regulator, RinA family
IKJKALAH_02025 6.5e-266
IKJKALAH_02026 3.8e-13
IKJKALAH_02027 6.7e-17
IKJKALAH_02028 3.4e-12 K Helix-turn-helix
IKJKALAH_02029 1.4e-12 K sequence-specific DNA binding
IKJKALAH_02030 6.4e-141 sip L Phage integrase, N-terminal SAM-like domain
IKJKALAH_02031 2.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IKJKALAH_02032 8.2e-48 veg S Biofilm formation stimulator VEG
IKJKALAH_02033 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IKJKALAH_02034 3.9e-70 rplI J binds to the 23S rRNA
IKJKALAH_02035 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IKJKALAH_02036 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IKJKALAH_02037 1.5e-77 F NUDIX domain
IKJKALAH_02038 4.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IKJKALAH_02039 0.0 S Bacterial membrane protein, YfhO
IKJKALAH_02040 9.9e-64 isaA GH23 M Immunodominant staphylococcal antigen A
IKJKALAH_02041 1.7e-91 lytE M LysM domain protein
IKJKALAH_02042 1e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKJKALAH_02043 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKJKALAH_02044 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKJKALAH_02045 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IKJKALAH_02046 6.3e-138 ymfM S sequence-specific DNA binding
IKJKALAH_02047 3.1e-242 ymfH S Peptidase M16
IKJKALAH_02048 4.8e-235 ymfF S Peptidase M16
IKJKALAH_02049 1.6e-45 yaaA S S4 domain protein YaaA
IKJKALAH_02050 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IKJKALAH_02051 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IKJKALAH_02052 3.1e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IKJKALAH_02053 4.2e-153 yvjA S membrane
IKJKALAH_02054 3.3e-305 ybiT S abc transporter atp-binding protein
IKJKALAH_02055 0.0 XK27_10405 S Bacterial membrane protein YfhO
IKJKALAH_02059 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
IKJKALAH_02060 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IKJKALAH_02061 1.1e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IKJKALAH_02062 8.5e-134 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)