ORF_ID e_value Gene_name EC_number CAZy COGs Description
EFFDNGOE_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EFFDNGOE_00002 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EFFDNGOE_00003 1.1e-29 yyzM S Protein conserved in bacteria
EFFDNGOE_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EFFDNGOE_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EFFDNGOE_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EFFDNGOE_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EFFDNGOE_00008 2.7e-61 divIC D Septum formation initiator
EFFDNGOE_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
EFFDNGOE_00011 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EFFDNGOE_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EFFDNGOE_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EFFDNGOE_00014 1.3e-137 L Transposase
EFFDNGOE_00015 1.1e-92 L Transposase
EFFDNGOE_00016 1.6e-55 L transposition
EFFDNGOE_00017 1.9e-86 L Integrase core domain protein
EFFDNGOE_00018 2.6e-12
EFFDNGOE_00031 5.3e-11
EFFDNGOE_00037 5.5e-139 mreC M Involved in formation and maintenance of cell shape
EFFDNGOE_00038 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EFFDNGOE_00039 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
EFFDNGOE_00040 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EFFDNGOE_00041 2.9e-218 araT 2.6.1.1 E Aminotransferase
EFFDNGOE_00042 1e-142 recO L Involved in DNA repair and RecF pathway recombination
EFFDNGOE_00043 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EFFDNGOE_00044 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EFFDNGOE_00045 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EFFDNGOE_00046 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EFFDNGOE_00047 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EFFDNGOE_00048 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EFFDNGOE_00049 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EFFDNGOE_00050 1.2e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EFFDNGOE_00051 4.8e-76 L transposase activity
EFFDNGOE_00052 1.4e-48 L transposition
EFFDNGOE_00053 1.4e-33 L Integrase core domain protein
EFFDNGOE_00054 2.3e-161 S CHAP domain
EFFDNGOE_00055 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
EFFDNGOE_00056 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EFFDNGOE_00057 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EFFDNGOE_00058 9.2e-141 1.1.1.169 H Ketopantoate reductase
EFFDNGOE_00059 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EFFDNGOE_00060 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EFFDNGOE_00061 2.6e-09 L Transposase
EFFDNGOE_00062 8.2e-70 argR K Regulates arginine biosynthesis genes
EFFDNGOE_00063 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EFFDNGOE_00064 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EFFDNGOE_00065 7e-34 S Protein of unknown function (DUF3021)
EFFDNGOE_00066 1.2e-61 KT phosphorelay signal transduction system
EFFDNGOE_00068 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EFFDNGOE_00070 1.2e-165 L integrase core domain
EFFDNGOE_00071 3.9e-122 L Transposase
EFFDNGOE_00072 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EFFDNGOE_00073 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
EFFDNGOE_00074 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
EFFDNGOE_00075 2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EFFDNGOE_00076 1.1e-65 spxA_2 1.20.4.1 P Belongs to the ArsC family
EFFDNGOE_00083 2.6e-10
EFFDNGOE_00086 1.9e-07
EFFDNGOE_00091 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFFDNGOE_00092 5.7e-222 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EFFDNGOE_00093 5.5e-36 XK27_02060 S Transglycosylase associated protein
EFFDNGOE_00094 1.8e-26 badR K DNA-binding transcription factor activity
EFFDNGOE_00095 1.7e-96 S reductase
EFFDNGOE_00096 1e-87 L Integrase core domain protein
EFFDNGOE_00097 3.2e-40 L transposition
EFFDNGOE_00098 7.3e-22 yocD 3.4.17.13 V carboxypeptidase activity
EFFDNGOE_00099 1.9e-86 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EFFDNGOE_00102 6.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
EFFDNGOE_00103 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EFFDNGOE_00104 1.1e-83 S Putative small multi-drug export protein
EFFDNGOE_00105 2.4e-75 ctsR K Belongs to the CtsR family
EFFDNGOE_00106 0.0 clpC O Belongs to the ClpA ClpB family
EFFDNGOE_00107 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EFFDNGOE_00108 4.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EFFDNGOE_00109 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EFFDNGOE_00110 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EFFDNGOE_00111 4.5e-143 S SseB protein N-terminal domain
EFFDNGOE_00112 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
EFFDNGOE_00113 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EFFDNGOE_00114 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EFFDNGOE_00117 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFFDNGOE_00118 3.5e-91 yacP S RNA-binding protein containing a PIN domain
EFFDNGOE_00119 3.4e-155 degV S DegV family
EFFDNGOE_00121 2.3e-31 K helix-turn-helix
EFFDNGOE_00122 1.6e-94 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFFDNGOE_00123 3.6e-57 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EFFDNGOE_00124 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EFFDNGOE_00125 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
EFFDNGOE_00126 1.5e-35 K sequence-specific DNA binding
EFFDNGOE_00128 0.0 S Lantibiotic dehydratase, C terminus
EFFDNGOE_00129 2.4e-231 spaC2 V Lanthionine synthetase C family protein
EFFDNGOE_00130 2.5e-183 EGP Major facilitator Superfamily
EFFDNGOE_00131 5.9e-24 3.6.4.12
EFFDNGOE_00132 6.5e-90 3.6.4.12 K Divergent AAA domain protein
EFFDNGOE_00133 9.3e-184 L Phage integrase family
EFFDNGOE_00134 1.7e-22
EFFDNGOE_00135 1.3e-154
EFFDNGOE_00137 1.3e-134 D ftsk spoiiie
EFFDNGOE_00138 5.3e-18 D FtsK/SpoIIIE family
EFFDNGOE_00141 9.7e-227 sthIM 2.1.1.72 L DNA methylase
EFFDNGOE_00142 0.0 res_1 3.1.21.5 S Type III restriction
EFFDNGOE_00144 2.2e-224 int L Belongs to the 'phage' integrase family
EFFDNGOE_00145 1.8e-38 S Helix-turn-helix domain
EFFDNGOE_00146 4.9e-173
EFFDNGOE_00148 3.4e-75 isp2 S pathogenesis
EFFDNGOE_00149 5.7e-91 tnp L Transposase
EFFDNGOE_00150 3.3e-225 capA M Bacterial capsule synthesis protein
EFFDNGOE_00151 3.6e-39 gcvR T UPF0237 protein
EFFDNGOE_00152 1.9e-242 XK27_08635 S UPF0210 protein
EFFDNGOE_00153 2.2e-38 ais G alpha-ribazole phosphatase activity
EFFDNGOE_00154 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EFFDNGOE_00155 1.3e-102 acmA 3.2.1.17 NU amidase activity
EFFDNGOE_00156 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EFFDNGOE_00157 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EFFDNGOE_00158 9.8e-298 dnaK O Heat shock 70 kDa protein
EFFDNGOE_00159 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EFFDNGOE_00160 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EFFDNGOE_00161 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
EFFDNGOE_00162 1.7e-60 hmpT S membrane
EFFDNGOE_00173 1.6e-12
EFFDNGOE_00176 0.0 amiA E ABC transporter, substrate-binding protein, family 5
EFFDNGOE_00177 2.5e-169 L Transposase
EFFDNGOE_00178 9.9e-19 S Domain of unknown function (DUF4649)
EFFDNGOE_00179 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EFFDNGOE_00180 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
EFFDNGOE_00181 6.5e-87
EFFDNGOE_00182 1.6e-77 sigH K DNA-templated transcription, initiation
EFFDNGOE_00183 4.6e-149 ykuT M mechanosensitive ion channel
EFFDNGOE_00184 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EFFDNGOE_00185 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EFFDNGOE_00186 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EFFDNGOE_00187 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
EFFDNGOE_00188 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
EFFDNGOE_00189 2e-177 prmA J Ribosomal protein L11 methyltransferase
EFFDNGOE_00190 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EFFDNGOE_00191 1.4e-42 F nucleotide catabolic process
EFFDNGOE_00192 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EFFDNGOE_00193 6.3e-186 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EFFDNGOE_00194 3.8e-81 nrdI F Belongs to the NrdI family
EFFDNGOE_00195 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EFFDNGOE_00196 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EFFDNGOE_00197 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EFFDNGOE_00198 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EFFDNGOE_00199 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EFFDNGOE_00200 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EFFDNGOE_00201 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EFFDNGOE_00202 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EFFDNGOE_00203 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EFFDNGOE_00204 6.5e-202 yhjX P Major Facilitator
EFFDNGOE_00205 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EFFDNGOE_00206 5e-94 V VanZ like family
EFFDNGOE_00207 1e-123 glnQ E abc transporter atp-binding protein
EFFDNGOE_00208 5.8e-275 glnP P ABC transporter
EFFDNGOE_00209 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EFFDNGOE_00210 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EFFDNGOE_00211 5.5e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
EFFDNGOE_00212 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EFFDNGOE_00213 6.3e-235 sufD O assembly protein SufD
EFFDNGOE_00214 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EFFDNGOE_00215 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
EFFDNGOE_00216 2.2e-273 sufB O assembly protein SufB
EFFDNGOE_00217 7e-10 oppA E ABC transporter substrate-binding protein
EFFDNGOE_00218 2e-138 oppA E ABC transporter substrate-binding protein
EFFDNGOE_00219 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFFDNGOE_00220 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFFDNGOE_00221 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFFDNGOE_00222 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EFFDNGOE_00223 3e-27 oppD P Belongs to the ABC transporter superfamily
EFFDNGOE_00224 2.5e-32 oppD P Belongs to the ABC transporter superfamily
EFFDNGOE_00225 1.2e-62 oppD P Belongs to the ABC transporter superfamily
EFFDNGOE_00226 2.7e-41 oppD P Belongs to the ABC transporter superfamily
EFFDNGOE_00227 7.5e-62 oppF P Belongs to the ABC transporter superfamily
EFFDNGOE_00228 3.4e-62 oppF P Belongs to the ABC transporter superfamily
EFFDNGOE_00229 6.4e-23
EFFDNGOE_00230 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EFFDNGOE_00231 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EFFDNGOE_00232 9.4e-223 EGP Major facilitator Superfamily
EFFDNGOE_00233 3.1e-72 adcR K transcriptional
EFFDNGOE_00234 8.3e-136 adcC P ABC transporter, ATP-binding protein
EFFDNGOE_00235 1.6e-127 adcB P ABC transporter (Permease
EFFDNGOE_00236 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
EFFDNGOE_00237 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
EFFDNGOE_00238 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
EFFDNGOE_00239 4.8e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EFFDNGOE_00240 6.6e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
EFFDNGOE_00241 1.1e-256 pgi 5.3.1.9 G Belongs to the GPI family
EFFDNGOE_00242 1.9e-127 yeeN K transcriptional regulatory protein
EFFDNGOE_00243 9.8e-50 yajC U protein transport
EFFDNGOE_00244 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EFFDNGOE_00245 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
EFFDNGOE_00246 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EFFDNGOE_00247 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EFFDNGOE_00248 0.0 WQ51_06230 S ABC transporter substrate binding protein
EFFDNGOE_00249 5.2e-142 cmpC S abc transporter atp-binding protein
EFFDNGOE_00250 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EFFDNGOE_00251 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EFFDNGOE_00252 4.4e-37 L Transposase
EFFDNGOE_00253 3.2e-10 L transposase activity
EFFDNGOE_00254 1.7e-51 L transposition
EFFDNGOE_00255 1.4e-33 L Integrase core domain protein
EFFDNGOE_00257 4.7e-43
EFFDNGOE_00258 6.8e-56 S TM2 domain
EFFDNGOE_00259 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EFFDNGOE_00260 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EFFDNGOE_00261 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EFFDNGOE_00262 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
EFFDNGOE_00263 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
EFFDNGOE_00264 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
EFFDNGOE_00265 6e-55 cof Q phosphatase activity
EFFDNGOE_00266 6.2e-35 cof Q phosphatase activity
EFFDNGOE_00267 1.6e-137 glcR K transcriptional regulator (DeoR family)
EFFDNGOE_00268 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EFFDNGOE_00270 3.8e-40 K transcriptional
EFFDNGOE_00272 2.6e-76 S thiolester hydrolase activity
EFFDNGOE_00273 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
EFFDNGOE_00274 1.3e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EFFDNGOE_00275 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EFFDNGOE_00276 1.9e-77 yhaI L Membrane
EFFDNGOE_00277 5.1e-259 pepC 3.4.22.40 E aminopeptidase
EFFDNGOE_00278 8.9e-104 L Transposase
EFFDNGOE_00279 5.3e-136 L Transposase
EFFDNGOE_00280 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EFFDNGOE_00281 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EFFDNGOE_00282 8.9e-95 ypsA S Belongs to the UPF0398 family
EFFDNGOE_00283 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EFFDNGOE_00284 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EFFDNGOE_00285 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
EFFDNGOE_00286 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
EFFDNGOE_00287 2.5e-23
EFFDNGOE_00288 5.7e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EFFDNGOE_00289 2.1e-82 XK27_09675 K -acetyltransferase
EFFDNGOE_00290 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EFFDNGOE_00291 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EFFDNGOE_00292 5.2e-59 L Integrase core domain protein
EFFDNGOE_00293 8.5e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFFDNGOE_00294 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EFFDNGOE_00295 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EFFDNGOE_00296 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
EFFDNGOE_00297 8.8e-98 ybhL S Belongs to the BI1 family
EFFDNGOE_00300 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EFFDNGOE_00301 3.7e-91 K transcriptional regulator
EFFDNGOE_00302 7.6e-36 yneF S UPF0154 protein
EFFDNGOE_00303 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EFFDNGOE_00304 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EFFDNGOE_00305 3.5e-99 XK27_09740 S Phosphoesterase
EFFDNGOE_00306 7.8e-85 ykuL S CBS domain
EFFDNGOE_00307 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
EFFDNGOE_00308 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EFFDNGOE_00309 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EFFDNGOE_00310 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EFFDNGOE_00311 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EFFDNGOE_00312 1.2e-258 trkH P Cation transport protein
EFFDNGOE_00313 1.3e-246 trkA P Potassium transporter peripheral membrane component
EFFDNGOE_00314 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EFFDNGOE_00315 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EFFDNGOE_00316 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
EFFDNGOE_00317 5.6e-161 K sequence-specific DNA binding
EFFDNGOE_00318 1.2e-32 V protein secretion by the type I secretion system
EFFDNGOE_00319 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EFFDNGOE_00320 1.2e-54 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EFFDNGOE_00321 1.8e-34 V protein secretion by the type I secretion system
EFFDNGOE_00322 2.3e-129 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EFFDNGOE_00323 1.8e-50 yhaI L Membrane
EFFDNGOE_00324 5e-84 S Domain of unknown function (DUF4173)
EFFDNGOE_00325 6.8e-95 ureI S AmiS/UreI family transporter
EFFDNGOE_00326 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EFFDNGOE_00327 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EFFDNGOE_00328 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EFFDNGOE_00329 6.6e-78 ureE O enzyme active site formation
EFFDNGOE_00330 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EFFDNGOE_00331 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EFFDNGOE_00332 3.4e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EFFDNGOE_00333 4.3e-175 cbiM P PDGLE domain
EFFDNGOE_00334 1.1e-136 P cobalt transport protein
EFFDNGOE_00335 1.6e-131 cbiO P ABC transporter
EFFDNGOE_00336 5.3e-153 ET amino acid transport
EFFDNGOE_00337 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFFDNGOE_00338 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
EFFDNGOE_00339 3.8e-205 EGP Transmembrane secretion effector
EFFDNGOE_00340 1.8e-153 ET amino acid transport
EFFDNGOE_00341 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
EFFDNGOE_00342 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
EFFDNGOE_00343 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
EFFDNGOE_00344 8.5e-36 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
EFFDNGOE_00345 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EFFDNGOE_00346 5.2e-98 metI P ABC transporter (Permease
EFFDNGOE_00347 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EFFDNGOE_00348 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
EFFDNGOE_00349 8e-94 S UPF0397 protein
EFFDNGOE_00350 0.0 ykoD P abc transporter atp-binding protein
EFFDNGOE_00351 1.2e-146 cbiQ P cobalt transport
EFFDNGOE_00352 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EFFDNGOE_00353 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
EFFDNGOE_00354 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
EFFDNGOE_00355 1.4e-243 P COG0168 Trk-type K transport systems, membrane components
EFFDNGOE_00356 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
EFFDNGOE_00357 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
EFFDNGOE_00358 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFFDNGOE_00359 3.3e-275 T PhoQ Sensor
EFFDNGOE_00360 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EFFDNGOE_00361 5e-218 dnaB L Replication initiation and membrane attachment
EFFDNGOE_00362 4e-167 dnaI L Primosomal protein DnaI
EFFDNGOE_00363 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EFFDNGOE_00364 9e-88 yrdC 3.5.1.19 Q isochorismatase
EFFDNGOE_00365 1.8e-85 L PFAM Integrase catalytic region
EFFDNGOE_00366 1.7e-54 L transposition
EFFDNGOE_00367 5e-23 L Transposase
EFFDNGOE_00368 2.3e-32 L transposase activity
EFFDNGOE_00369 7.6e-55 L Transposase
EFFDNGOE_00370 7.2e-77 L Transposase
EFFDNGOE_00371 8.9e-56 L Transposase
EFFDNGOE_00373 4.3e-41 L Protein of unknown function (DUF3991)
EFFDNGOE_00374 2.8e-160 L Transposase DDE domain
EFFDNGOE_00375 9.5e-17 lytN 3.5.1.104 M LysM domain
EFFDNGOE_00376 1.3e-125 tnp L DDE domain
EFFDNGOE_00377 2.1e-12 G gluconolactonase activity
EFFDNGOE_00378 0.0 M domain protein
EFFDNGOE_00379 1.4e-36 L Integrase core domain
EFFDNGOE_00380 2.6e-94 L Integrase core domain
EFFDNGOE_00381 1.3e-221 L Transposase
EFFDNGOE_00382 8e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EFFDNGOE_00383 4.2e-62 manO S protein conserved in bacteria
EFFDNGOE_00384 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
EFFDNGOE_00385 5e-108 manM G pts system
EFFDNGOE_00386 1.1e-181 manL 2.7.1.191 G pts system
EFFDNGOE_00387 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
EFFDNGOE_00388 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
EFFDNGOE_00389 2.5e-248 pbuO S permease
EFFDNGOE_00390 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
EFFDNGOE_00391 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
EFFDNGOE_00392 2.5e-220 brpA K Transcriptional
EFFDNGOE_00393 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
EFFDNGOE_00394 3.1e-212 nusA K Participates in both transcription termination and antitermination
EFFDNGOE_00395 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
EFFDNGOE_00396 2e-46 ylxQ J ribosomal protein
EFFDNGOE_00397 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EFFDNGOE_00398 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EFFDNGOE_00399 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
EFFDNGOE_00400 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
EFFDNGOE_00401 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
EFFDNGOE_00402 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
EFFDNGOE_00403 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EFFDNGOE_00404 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
EFFDNGOE_00405 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
EFFDNGOE_00406 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
EFFDNGOE_00407 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EFFDNGOE_00409 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EFFDNGOE_00410 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EFFDNGOE_00411 1.2e-74 ylbF S Belongs to the UPF0342 family
EFFDNGOE_00412 7.1e-46 ylbG S UPF0298 protein
EFFDNGOE_00413 1.3e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
EFFDNGOE_00414 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
EFFDNGOE_00415 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
EFFDNGOE_00416 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
EFFDNGOE_00417 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
EFFDNGOE_00418 6.8e-69 acuB S IMP dehydrogenase activity
EFFDNGOE_00419 8.9e-41 acuB S IMP dehydrogenase activity
EFFDNGOE_00420 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EFFDNGOE_00421 1.1e-110 yvyE 3.4.13.9 S YigZ family
EFFDNGOE_00422 5.9e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EFFDNGOE_00423 1.7e-122 comFC S Competence protein
EFFDNGOE_00424 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EFFDNGOE_00432 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
EFFDNGOE_00433 6.4e-108 S Domain of unknown function (DUF1803)
EFFDNGOE_00434 1.3e-101 ygaC J Belongs to the UPF0374 family
EFFDNGOE_00435 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
EFFDNGOE_00436 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFFDNGOE_00437 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
EFFDNGOE_00438 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
EFFDNGOE_00439 1.6e-114 S Haloacid dehalogenase-like hydrolase
EFFDNGOE_00440 6.9e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
EFFDNGOE_00441 4e-72 marR K Transcriptional regulator, MarR family
EFFDNGOE_00442 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EFFDNGOE_00443 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EFFDNGOE_00444 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
EFFDNGOE_00445 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EFFDNGOE_00446 1.6e-126 IQ reductase
EFFDNGOE_00447 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EFFDNGOE_00448 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EFFDNGOE_00449 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EFFDNGOE_00450 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EFFDNGOE_00451 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EFFDNGOE_00452 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EFFDNGOE_00453 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EFFDNGOE_00454 1.1e-65 tnp L Transposase
EFFDNGOE_00455 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
EFFDNGOE_00456 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
EFFDNGOE_00457 4.7e-27 L Transposase and inactivated derivatives, TnpA family
EFFDNGOE_00458 1.1e-65 tnp L Transposase
EFFDNGOE_00460 2.7e-82 S Protein of unknown function (DUF3114)
EFFDNGOE_00461 1.1e-176 S Protein of unknown function (DUF3114)
EFFDNGOE_00462 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
EFFDNGOE_00463 7.7e-198 V (ABC) transporter
EFFDNGOE_00464 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
EFFDNGOE_00465 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
EFFDNGOE_00466 1.1e-113 K sequence-specific DNA binding
EFFDNGOE_00467 8.4e-155 L COG2801 Transposase and inactivated derivatives
EFFDNGOE_00468 6.6e-38 L transposase activity
EFFDNGOE_00469 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
EFFDNGOE_00470 8.9e-84 L Transposase
EFFDNGOE_00471 5.5e-122 fruR K transcriptional
EFFDNGOE_00472 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EFFDNGOE_00473 0.0 fruA 2.7.1.202 G phosphotransferase system
EFFDNGOE_00474 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EFFDNGOE_00475 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EFFDNGOE_00477 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
EFFDNGOE_00478 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EFFDNGOE_00479 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EFFDNGOE_00480 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EFFDNGOE_00481 6.4e-29 2.3.1.128 K acetyltransferase
EFFDNGOE_00482 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
EFFDNGOE_00483 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EFFDNGOE_00484 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EFFDNGOE_00485 2.6e-64 WQ51_03320 S cog cog4835
EFFDNGOE_00486 9.8e-91 XK27_08360 S EDD domain protein, DegV family
EFFDNGOE_00487 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EFFDNGOE_00488 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EFFDNGOE_00489 0.0 yfmR S abc transporter atp-binding protein
EFFDNGOE_00490 7.2e-25 U response to pH
EFFDNGOE_00491 6.5e-77 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
EFFDNGOE_00492 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
EFFDNGOE_00493 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
EFFDNGOE_00494 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EFFDNGOE_00495 1.9e-77 K DNA-binding transcription factor activity
EFFDNGOE_00496 0.0 lmrA1 V abc transporter atp-binding protein
EFFDNGOE_00497 0.0 lmrA2 V abc transporter atp-binding protein
EFFDNGOE_00498 1.4e-45 K Acetyltransferase (GNAT) family
EFFDNGOE_00499 1.3e-120 sptS 2.7.13.3 T Histidine kinase
EFFDNGOE_00500 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EFFDNGOE_00501 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EFFDNGOE_00502 1.7e-159 cvfB S Protein conserved in bacteria
EFFDNGOE_00503 7.4e-35 yozE S Belongs to the UPF0346 family
EFFDNGOE_00504 1.5e-123 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
EFFDNGOE_00505 2.3e-61 rlpA M LysM domain protein
EFFDNGOE_00506 8e-191 phoH T phosphate starvation-inducible protein PhoH
EFFDNGOE_00510 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EFFDNGOE_00511 1.8e-164 K transcriptional regulator (lysR family)
EFFDNGOE_00512 1.4e-186 coiA 3.6.4.12 S Competence protein
EFFDNGOE_00513 0.0 pepF E oligoendopeptidase F
EFFDNGOE_00514 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
EFFDNGOE_00515 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
EFFDNGOE_00516 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EFFDNGOE_00517 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EFFDNGOE_00518 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EFFDNGOE_00519 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
EFFDNGOE_00520 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EFFDNGOE_00521 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
EFFDNGOE_00522 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EFFDNGOE_00523 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EFFDNGOE_00524 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EFFDNGOE_00525 1.4e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EFFDNGOE_00526 2.2e-130 yxkH G deacetylase
EFFDNGOE_00527 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EFFDNGOE_00528 6.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EFFDNGOE_00529 1.4e-151 rarD S Transporter
EFFDNGOE_00530 2.9e-15 T peptidase
EFFDNGOE_00531 8.9e-14 coiA 3.6.4.12 S Competence protein
EFFDNGOE_00532 8e-51 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EFFDNGOE_00533 5.9e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EFFDNGOE_00534 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EFFDNGOE_00535 3.3e-250 L Transposase
EFFDNGOE_00536 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFFDNGOE_00537 2.4e-114 atpB C it plays a direct role in the translocation of protons across the membrane
EFFDNGOE_00538 3.3e-78 atpF C ATP synthase F(0) sector subunit b
EFFDNGOE_00539 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EFFDNGOE_00540 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EFFDNGOE_00541 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EFFDNGOE_00542 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EFFDNGOE_00543 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EFFDNGOE_00544 2.8e-230 ftsW D Belongs to the SEDS family
EFFDNGOE_00545 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EFFDNGOE_00546 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EFFDNGOE_00547 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EFFDNGOE_00548 6.4e-162 holB 2.7.7.7 L dna polymerase iii
EFFDNGOE_00549 1.2e-135 yaaT S stage 0 sporulation protein
EFFDNGOE_00550 9.5e-55 yabA L Involved in initiation control of chromosome replication
EFFDNGOE_00551 4.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EFFDNGOE_00552 2.9e-232 amt P Ammonium Transporter
EFFDNGOE_00553 1.2e-52 glnB K Belongs to the P(II) protein family
EFFDNGOE_00554 9.2e-105 mur1 NU mannosyl-glycoprotein
EFFDNGOE_00555 2.9e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
EFFDNGOE_00556 1.5e-114 nptA P COG1283 Na phosphate symporter
EFFDNGOE_00557 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EFFDNGOE_00558 7.4e-55
EFFDNGOE_00559 4.4e-26
EFFDNGOE_00560 1.2e-61
EFFDNGOE_00561 1.7e-32 S membrane
EFFDNGOE_00562 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EFFDNGOE_00563 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EFFDNGOE_00564 4.5e-39 ynzC S UPF0291 protein
EFFDNGOE_00565 1.8e-254 cycA E permease
EFFDNGOE_00566 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
EFFDNGOE_00567 4.8e-24 pts33BCA G pts system
EFFDNGOE_00568 5.8e-71 pts33BCA G pts system
EFFDNGOE_00569 9.4e-119 pts33BCA G pts system
EFFDNGOE_00570 1.4e-75 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
EFFDNGOE_00571 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EFFDNGOE_00577 1.4e-167 fhuR K transcriptional regulator (lysR family)
EFFDNGOE_00578 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EFFDNGOE_00579 2.9e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EFFDNGOE_00580 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EFFDNGOE_00581 3.7e-227 pyrP F uracil Permease
EFFDNGOE_00582 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EFFDNGOE_00583 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
EFFDNGOE_00584 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
EFFDNGOE_00585 5.1e-131 2.1.1.223 S Putative SAM-dependent methyltransferase
EFFDNGOE_00586 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EFFDNGOE_00587 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EFFDNGOE_00588 1.7e-59 V permease protein
EFFDNGOE_00589 4.6e-43 V efflux transmembrane transporter activity
EFFDNGOE_00590 7.2e-24 ytrF V efflux transmembrane transporter activity
EFFDNGOE_00591 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EFFDNGOE_00592 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EFFDNGOE_00594 0.0 mdlB V abc transporter atp-binding protein
EFFDNGOE_00595 0.0 lmrA V abc transporter atp-binding protein
EFFDNGOE_00596 1.3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EFFDNGOE_00597 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EFFDNGOE_00598 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
EFFDNGOE_00599 2.5e-132 rr02 KT response regulator
EFFDNGOE_00600 2.5e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EFFDNGOE_00601 2.8e-168 V ABC transporter
EFFDNGOE_00602 5.4e-122 sagI S ABC-2 type transporter
EFFDNGOE_00603 6.9e-197 yceA S Belongs to the UPF0176 family
EFFDNGOE_00604 8e-28 XK27_00085 K Transcriptional
EFFDNGOE_00605 1.9e-22
EFFDNGOE_00606 6.5e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
EFFDNGOE_00607 2.5e-113 S VIT family
EFFDNGOE_00608 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EFFDNGOE_00609 7e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EFFDNGOE_00610 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
EFFDNGOE_00611 1.3e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EFFDNGOE_00612 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EFFDNGOE_00613 8.8e-104 GBS0088 J protein conserved in bacteria
EFFDNGOE_00614 7.9e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EFFDNGOE_00615 1.4e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EFFDNGOE_00616 1e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
EFFDNGOE_00617 2.4e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EFFDNGOE_00618 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EFFDNGOE_00619 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
EFFDNGOE_00620 2.5e-21
EFFDNGOE_00621 1.7e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EFFDNGOE_00623 3e-29 U protein secretion
EFFDNGOE_00624 4.2e-68 U protein secretion
EFFDNGOE_00625 4.4e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
EFFDNGOE_00626 1.2e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EFFDNGOE_00627 5.5e-49 XK27_13030
EFFDNGOE_00628 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EFFDNGOE_00629 2.3e-57 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EFFDNGOE_00630 1.6e-70 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EFFDNGOE_00631 1.1e-161 S Protein of unknown function (DUF3114)
EFFDNGOE_00632 1.6e-22 S Protein of unknown function (DUF3114)
EFFDNGOE_00633 1.1e-116 yqfA K protein, Hemolysin III
EFFDNGOE_00634 1e-25 K hmm pf08876
EFFDNGOE_00635 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EFFDNGOE_00636 1.7e-218 mvaS 2.3.3.10 I synthase
EFFDNGOE_00637 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EFFDNGOE_00638 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EFFDNGOE_00639 9.7e-22
EFFDNGOE_00640 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EFFDNGOE_00641 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
EFFDNGOE_00642 1.5e-250 mmuP E amino acid
EFFDNGOE_00643 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
EFFDNGOE_00644 1.4e-29 S Domain of unknown function (DUF1912)
EFFDNGOE_00645 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
EFFDNGOE_00646 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EFFDNGOE_00647 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EFFDNGOE_00648 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EFFDNGOE_00649 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
EFFDNGOE_00650 4.8e-16 S Protein of unknown function (DUF2969)
EFFDNGOE_00653 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
EFFDNGOE_00656 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
EFFDNGOE_00657 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
EFFDNGOE_00658 3.7e-70 M Pfam SNARE associated Golgi protein
EFFDNGOE_00659 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
EFFDNGOE_00660 1.2e-65 S oxidoreductase
EFFDNGOE_00661 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
EFFDNGOE_00662 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EFFDNGOE_00663 0.0 clpE O Belongs to the ClpA ClpB family
EFFDNGOE_00664 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EFFDNGOE_00665 1.3e-34 ykuJ S protein conserved in bacteria
EFFDNGOE_00666 3.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
EFFDNGOE_00667 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
EFFDNGOE_00668 3.1e-78 feoA P FeoA domain protein
EFFDNGOE_00669 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EFFDNGOE_00671 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EFFDNGOE_00672 2.2e-45 K sequence-specific DNA binding
EFFDNGOE_00673 1.5e-35 yugF I carboxylic ester hydrolase activity
EFFDNGOE_00674 7.5e-23 I Alpha/beta hydrolase family
EFFDNGOE_00675 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EFFDNGOE_00676 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EFFDNGOE_00677 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
EFFDNGOE_00678 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EFFDNGOE_00679 5.8e-64 licT K transcriptional antiterminator
EFFDNGOE_00680 6.8e-53 licT K transcriptional antiterminator
EFFDNGOE_00681 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EFFDNGOE_00682 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EFFDNGOE_00683 8.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EFFDNGOE_00684 7.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EFFDNGOE_00685 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EFFDNGOE_00686 2.5e-220 mdtG EGP Major facilitator Superfamily
EFFDNGOE_00687 2e-33 secG U Preprotein translocase subunit SecG
EFFDNGOE_00688 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EFFDNGOE_00689 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EFFDNGOE_00690 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EFFDNGOE_00691 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
EFFDNGOE_00692 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
EFFDNGOE_00693 4.4e-183 ccpA K Catabolite control protein A
EFFDNGOE_00694 2.8e-28 yyaQ S YjbR
EFFDNGOE_00695 6.6e-101 yyaQ V Protein conserved in bacteria
EFFDNGOE_00696 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EFFDNGOE_00697 1e-78 yueI S Protein of unknown function (DUF1694)
EFFDNGOE_00698 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EFFDNGOE_00699 2e-25 WQ51_00785
EFFDNGOE_00700 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EFFDNGOE_00701 2e-219 ywbD 2.1.1.191 J Methyltransferase
EFFDNGOE_00702 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EFFDNGOE_00703 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EFFDNGOE_00704 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EFFDNGOE_00705 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EFFDNGOE_00706 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EFFDNGOE_00707 3.2e-53 yheA S Belongs to the UPF0342 family
EFFDNGOE_00708 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EFFDNGOE_00709 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EFFDNGOE_00710 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EFFDNGOE_00711 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
EFFDNGOE_00712 6.4e-252 msrR K Transcriptional regulator
EFFDNGOE_00713 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
EFFDNGOE_00714 7e-203 I acyl-CoA dehydrogenase
EFFDNGOE_00715 4.5e-97 mip S hydroperoxide reductase activity
EFFDNGOE_00716 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EFFDNGOE_00717 8.9e-20
EFFDNGOE_00718 3.2e-46
EFFDNGOE_00719 1e-31 K Cro/C1-type HTH DNA-binding domain
EFFDNGOE_00720 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
EFFDNGOE_00721 4.8e-33 estA E GDSL-like Lipase/Acylhydrolase
EFFDNGOE_00722 1.1e-94
EFFDNGOE_00723 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EFFDNGOE_00724 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFFDNGOE_00725 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFFDNGOE_00726 9e-195 S CRISPR-associated protein Csn2 subfamily St
EFFDNGOE_00727 2.3e-145 ycgQ S TIGR03943 family
EFFDNGOE_00728 1.2e-155 XK27_03015 S permease
EFFDNGOE_00730 0.0 yhgF K Transcriptional accessory protein
EFFDNGOE_00731 9.9e-42 pspC KT PspC domain
EFFDNGOE_00732 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EFFDNGOE_00733 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EFFDNGOE_00735 5.5e-69 ytxH S General stress protein
EFFDNGOE_00737 2e-177 yegQ O Peptidase U32
EFFDNGOE_00738 3.4e-252 yegQ O Peptidase U32
EFFDNGOE_00739 8.1e-46 S CHY zinc finger
EFFDNGOE_00740 8.4e-88 bioY S biotin synthase
EFFDNGOE_00742 1.1e-33 XK27_12190 S protein conserved in bacteria
EFFDNGOE_00743 7.3e-234 mntH P H( )-stimulated, divalent metal cation uptake system
EFFDNGOE_00744 4.8e-11
EFFDNGOE_00745 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
EFFDNGOE_00746 1.2e-224 mutH L DNA mismatch repair enzyme MutH
EFFDNGOE_00747 5.2e-29 S SIR2-like domain
EFFDNGOE_00748 1.2e-33 S SIR2-like domain
EFFDNGOE_00749 1.9e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EFFDNGOE_00750 1.5e-154 M LysM domain
EFFDNGOE_00751 5.9e-16
EFFDNGOE_00752 9.8e-174 S hydrolase
EFFDNGOE_00753 5.1e-116 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
EFFDNGOE_00754 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EFFDNGOE_00755 2.2e-144 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
EFFDNGOE_00756 2.1e-27 P Hemerythrin HHE cation binding domain protein
EFFDNGOE_00757 1.4e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EFFDNGOE_00758 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
EFFDNGOE_00759 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
EFFDNGOE_00760 8.3e-76 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EFFDNGOE_00761 1.4e-44 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EFFDNGOE_00762 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
EFFDNGOE_00763 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
EFFDNGOE_00764 9.3e-68 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
EFFDNGOE_00766 2.5e-44
EFFDNGOE_00767 3e-38
EFFDNGOE_00768 8.8e-157 spd F DNA RNA non-specific endonuclease
EFFDNGOE_00769 1.5e-92 lemA S LemA family
EFFDNGOE_00770 1.8e-135 htpX O Belongs to the peptidase M48B family
EFFDNGOE_00771 5.1e-73 S Psort location CytoplasmicMembrane, score
EFFDNGOE_00772 6.2e-56 S Domain of unknown function (DUF4430)
EFFDNGOE_00773 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EFFDNGOE_00774 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
EFFDNGOE_00775 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
EFFDNGOE_00776 1.4e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
EFFDNGOE_00777 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
EFFDNGOE_00778 1.6e-91 dps P Belongs to the Dps family
EFFDNGOE_00779 1.1e-80 perR P Belongs to the Fur family
EFFDNGOE_00780 8.4e-28 yqgQ S protein conserved in bacteria
EFFDNGOE_00781 1.6e-177 glk 2.7.1.2 G Glucokinase
EFFDNGOE_00782 0.0 typA T GTP-binding protein TypA
EFFDNGOE_00784 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EFFDNGOE_00785 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EFFDNGOE_00786 6.9e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EFFDNGOE_00787 1.1e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EFFDNGOE_00788 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EFFDNGOE_00789 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EFFDNGOE_00790 2e-95 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EFFDNGOE_00791 8.8e-35 yggT D integral membrane protein
EFFDNGOE_00792 4.7e-143 ylmH T S4 RNA-binding domain
EFFDNGOE_00793 3.3e-134 divIVA D Cell division protein DivIVA
EFFDNGOE_00794 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EFFDNGOE_00795 3.2e-45 L Transposase
EFFDNGOE_00797 8.8e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
EFFDNGOE_00798 2e-45 rpmE2 J 50S ribosomal protein L31
EFFDNGOE_00799 1.9e-175 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EFFDNGOE_00800 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
EFFDNGOE_00801 8.9e-155 gst O Glutathione S-transferase
EFFDNGOE_00802 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EFFDNGOE_00803 4.5e-111 tdk 2.7.1.21 F thymidine kinase
EFFDNGOE_00804 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EFFDNGOE_00805 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EFFDNGOE_00806 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EFFDNGOE_00807 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EFFDNGOE_00808 6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
EFFDNGOE_00809 2.4e-107 pvaA M lytic transglycosylase activity
EFFDNGOE_00810 0.0 yfiB1 V abc transporter atp-binding protein
EFFDNGOE_00811 0.0 XK27_10035 V abc transporter atp-binding protein
EFFDNGOE_00812 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
EFFDNGOE_00813 9.3e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFFDNGOE_00814 1.3e-237 dltB M Membrane protein involved in D-alanine export
EFFDNGOE_00815 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EFFDNGOE_00816 5.2e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EFFDNGOE_00817 2.5e-250 L Transposase
EFFDNGOE_00818 0.0 3.6.3.8 P cation transport ATPase
EFFDNGOE_00819 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
EFFDNGOE_00820 5.1e-106 V Abi-like protein
EFFDNGOE_00821 1.7e-146 2.1.1.37 H cytosine-specific methyltransferase
EFFDNGOE_00822 2.6e-72 hpaIIR 3.1.21.4 L HpaII restriction endonuclease
EFFDNGOE_00823 3e-44 ymbI L transposase activity
EFFDNGOE_00824 4e-22 L Belongs to the 'phage' integrase family
EFFDNGOE_00825 1.4e-66 S tRNA_anti-like
EFFDNGOE_00826 2e-103
EFFDNGOE_00828 2.3e-12
EFFDNGOE_00830 2e-296 S DNA primase
EFFDNGOE_00831 3e-164 KL Phage plasmid primase P4 family
EFFDNGOE_00832 6.9e-22
EFFDNGOE_00837 5.5e-17 K TRANSCRIPTIONal
EFFDNGOE_00838 6e-39 K Helix-turn-helix
EFFDNGOE_00839 7.1e-217 sip L Belongs to the 'phage' integrase family
EFFDNGOE_00841 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EFFDNGOE_00842 7.3e-166 metF 1.5.1.20 C reductase
EFFDNGOE_00843 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EFFDNGOE_00844 1.6e-92 panT S ECF transporter, substrate-specific component
EFFDNGOE_00845 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EFFDNGOE_00846 6.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
EFFDNGOE_00847 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EFFDNGOE_00848 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFFDNGOE_00849 4.3e-41 T PhoQ Sensor
EFFDNGOE_00850 1.1e-13 T PhoQ Sensor
EFFDNGOE_00851 9.2e-110 T PhoQ Sensor
EFFDNGOE_00852 1.2e-165 L integrase core domain
EFFDNGOE_00853 4.7e-117 L Transposase
EFFDNGOE_00854 2.1e-30 rpsT J rRNA binding
EFFDNGOE_00855 2.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
EFFDNGOE_00856 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
EFFDNGOE_00857 1.3e-24 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
EFFDNGOE_00858 7.5e-101 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
EFFDNGOE_00859 5.5e-29 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EFFDNGOE_00860 1.5e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EFFDNGOE_00861 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EFFDNGOE_00862 1.5e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EFFDNGOE_00863 2.7e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EFFDNGOE_00864 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
EFFDNGOE_00865 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
EFFDNGOE_00866 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EFFDNGOE_00867 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EFFDNGOE_00868 3.1e-81 ypmB S Protein conserved in bacteria
EFFDNGOE_00869 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EFFDNGOE_00870 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EFFDNGOE_00871 1.5e-07
EFFDNGOE_00872 2.4e-30
EFFDNGOE_00873 3e-13
EFFDNGOE_00874 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
EFFDNGOE_00875 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EFFDNGOE_00876 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
EFFDNGOE_00877 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EFFDNGOE_00878 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
EFFDNGOE_00879 4.2e-18 D nuclear chromosome segregation
EFFDNGOE_00880 5.3e-136 yejC S cyclic nucleotide-binding protein
EFFDNGOE_00881 1.2e-163 rapZ S Displays ATPase and GTPase activities
EFFDNGOE_00882 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EFFDNGOE_00883 8.7e-162 whiA K May be required for sporulation
EFFDNGOE_00884 8e-90 pepD E Dipeptidase
EFFDNGOE_00885 5.8e-41 pepD E dipeptidase activity
EFFDNGOE_00886 5.4e-32 cspD K Cold shock protein domain
EFFDNGOE_00887 1.6e-249 L Transposase
EFFDNGOE_00888 9.4e-43 K Cold-Shock Protein
EFFDNGOE_00889 2.9e-131 L Transposase
EFFDNGOE_00890 8e-59 L Transposase
EFFDNGOE_00891 0.0 copB 3.6.3.4 P P-type ATPase
EFFDNGOE_00892 1.6e-88 L Transposase
EFFDNGOE_00893 8.6e-94 L Transposase
EFFDNGOE_00894 4.4e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EFFDNGOE_00895 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EFFDNGOE_00896 3.5e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EFFDNGOE_00897 3.3e-98 cysE 2.3.1.30 E serine acetyltransferase
EFFDNGOE_00898 6.3e-54 L Transposase
EFFDNGOE_00899 5.4e-104 L Transposase
EFFDNGOE_00900 5.2e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
EFFDNGOE_00901 5.2e-113 hsdM 2.1.1.72 V type I restriction-modification system
EFFDNGOE_00902 2.9e-154 glcU U Glucose uptake
EFFDNGOE_00903 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
EFFDNGOE_00904 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
EFFDNGOE_00905 3.7e-88 XK27_10720 D peptidase activity
EFFDNGOE_00906 2.1e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
EFFDNGOE_00907 1.7e-08
EFFDNGOE_00908 1.5e-170 yeiH S Membrane
EFFDNGOE_00909 1.9e-119 mur1 NU muramidase
EFFDNGOE_00910 6.6e-71 L transposition
EFFDNGOE_00911 4.5e-166 cpsY K Transcriptional regulator
EFFDNGOE_00912 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EFFDNGOE_00913 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
EFFDNGOE_00914 5.3e-105 artQ P ABC transporter (Permease
EFFDNGOE_00915 3.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
EFFDNGOE_00916 1.4e-158 aatB ET ABC transporter substrate-binding protein
EFFDNGOE_00917 3.1e-142 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFFDNGOE_00918 2.3e-62 adhP 1.1.1.1 C alcohol dehydrogenase
EFFDNGOE_00919 7.4e-110 adhP 1.1.1.1 C alcohol dehydrogenase
EFFDNGOE_00921 1.1e-20
EFFDNGOE_00922 0.0 res_1 3.1.21.5 S Type III restriction
EFFDNGOE_00923 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
EFFDNGOE_00924 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EFFDNGOE_00925 2e-126 gntR1 K transcriptional
EFFDNGOE_00926 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EFFDNGOE_00927 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EFFDNGOE_00928 2.4e-87 niaX
EFFDNGOE_00929 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
EFFDNGOE_00930 6.9e-127 K DNA-binding helix-turn-helix protein
EFFDNGOE_00931 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EFFDNGOE_00932 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFFDNGOE_00933 1.1e-167 GK ROK family
EFFDNGOE_00934 2.4e-158 dprA LU DNA protecting protein DprA
EFFDNGOE_00935 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EFFDNGOE_00936 5.1e-153 S TraX protein
EFFDNGOE_00937 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFFDNGOE_00938 6.9e-251 T PhoQ Sensor
EFFDNGOE_00939 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EFFDNGOE_00940 1.9e-152 XK27_05470 E Methionine synthase
EFFDNGOE_00941 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EFFDNGOE_00942 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EFFDNGOE_00943 6.8e-51 IQ Acetoin reductase
EFFDNGOE_00944 3.9e-19 IQ Acetoin reductase
EFFDNGOE_00945 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EFFDNGOE_00949 4.1e-53 K peptidyl-tyrosine sulfation
EFFDNGOE_00950 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EFFDNGOE_00953 1.3e-212 pqqE C radical SAM domain protein
EFFDNGOE_00954 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
EFFDNGOE_00955 6.6e-61 EGP Major facilitator Superfamily
EFFDNGOE_00956 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EFFDNGOE_00957 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
EFFDNGOE_00958 1e-193 L Transposase
EFFDNGOE_00959 6.1e-13 L Transposase
EFFDNGOE_00961 1.2e-103 K Transcriptional regulator, TetR family
EFFDNGOE_00962 1.2e-158 czcD P cation diffusion facilitator family transporter
EFFDNGOE_00963 1e-209 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EFFDNGOE_00964 8.1e-52 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
EFFDNGOE_00965 2.7e-106 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
EFFDNGOE_00966 6e-08 S Hydrolases of the alpha beta superfamily
EFFDNGOE_00967 1.8e-16 S Alpha/beta hydrolase of unknown function (DUF915)
EFFDNGOE_00968 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
EFFDNGOE_00971 2.6e-143 2.4.2.3 F Phosphorylase superfamily
EFFDNGOE_00972 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
EFFDNGOE_00973 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
EFFDNGOE_00974 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
EFFDNGOE_00975 9.6e-72 dinF V Mate efflux family protein
EFFDNGOE_00976 5.1e-26 dinF V drug transmembrane transporter activity
EFFDNGOE_00977 6.5e-266 S Psort location CytoplasmicMembrane, score
EFFDNGOE_00978 1.7e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EFFDNGOE_00980 2.1e-98 S TraX protein
EFFDNGOE_00981 3.2e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
EFFDNGOE_00982 6.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EFFDNGOE_00983 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EFFDNGOE_00984 1.8e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFFDNGOE_00985 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFFDNGOE_00986 1.3e-131 cas6 S CRISPR-associated endoribonuclease Cas6
EFFDNGOE_00987 0.0 csm1 S CRISPR-associated protein Csm1 family
EFFDNGOE_00988 5.6e-62 csm2 L Pfam:DUF310
EFFDNGOE_00989 1.1e-116 csm3 L RAMP superfamily
EFFDNGOE_00990 1.4e-164 csm4 L CRISPR-associated RAMP protein, Csm4 family
EFFDNGOE_00991 1.9e-203 csm5 L CRISPR-associated RAMP protein, Csm5 family
EFFDNGOE_00992 3.4e-61 csm6 S Psort location Cytoplasmic, score
EFFDNGOE_00993 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EFFDNGOE_00994 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EFFDNGOE_00995 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
EFFDNGOE_00997 7.9e-266 dtpT E transporter
EFFDNGOE_00998 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
EFFDNGOE_00999 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
EFFDNGOE_01000 1.8e-67 yecS P ABC transporter (Permease
EFFDNGOE_01002 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
EFFDNGOE_01003 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
EFFDNGOE_01004 1.4e-104 yfiF3 K sequence-specific DNA binding
EFFDNGOE_01005 1.3e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EFFDNGOE_01006 1.8e-240 agcS E (Alanine) symporter
EFFDNGOE_01007 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EFFDNGOE_01008 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
EFFDNGOE_01009 1.8e-59 Q phosphatase activity
EFFDNGOE_01010 9.3e-62 S haloacid dehalogenase-like hydrolase
EFFDNGOE_01011 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EFFDNGOE_01012 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
EFFDNGOE_01013 3.6e-136 XK27_04775 S hemerythrin HHE cation binding domain
EFFDNGOE_01014 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
EFFDNGOE_01015 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EFFDNGOE_01016 2.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EFFDNGOE_01017 2.1e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EFFDNGOE_01018 1.9e-43 yktA S Belongs to the UPF0223 family
EFFDNGOE_01019 1.1e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EFFDNGOE_01020 1.5e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EFFDNGOE_01021 4.3e-158 pstS P phosphate
EFFDNGOE_01022 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
EFFDNGOE_01023 5.9e-155 pstA P phosphate transport system permease
EFFDNGOE_01024 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EFFDNGOE_01025 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EFFDNGOE_01026 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
EFFDNGOE_01027 0.0 pepN 3.4.11.2 E aminopeptidase
EFFDNGOE_01028 1.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
EFFDNGOE_01029 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
EFFDNGOE_01031 3.7e-09
EFFDNGOE_01032 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EFFDNGOE_01033 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
EFFDNGOE_01034 2.3e-23 L Transposase
EFFDNGOE_01035 4.6e-25 tatA U protein secretion
EFFDNGOE_01036 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EFFDNGOE_01037 3.9e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
EFFDNGOE_01038 1.5e-233 ycdB P peroxidase
EFFDNGOE_01039 4.6e-152 ycdO P periplasmic lipoprotein involved in iron transport
EFFDNGOE_01040 6.5e-177 fatB P ABC-type enterochelin transport system, periplasmic component
EFFDNGOE_01041 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
EFFDNGOE_01042 1.9e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFFDNGOE_01043 4.8e-52 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFFDNGOE_01044 1.7e-91 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EFFDNGOE_01045 2e-139 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFFDNGOE_01046 3.8e-54 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFFDNGOE_01047 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFFDNGOE_01048 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFFDNGOE_01049 1.9e-37 3.5.1.28 NU amidase activity
EFFDNGOE_01050 8.5e-266 3.5.1.28 NU amidase activity
EFFDNGOE_01051 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EFFDNGOE_01052 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EFFDNGOE_01053 0.0 lpdA 1.8.1.4 C Dehydrogenase
EFFDNGOE_01054 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EFFDNGOE_01055 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EFFDNGOE_01056 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EFFDNGOE_01057 5e-38 P membrane protein (DUF2207)
EFFDNGOE_01058 5.7e-66 S the current gene model (or a revised gene model) may contain a frame shift
EFFDNGOE_01059 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EFFDNGOE_01060 7.2e-126 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EFFDNGOE_01061 4e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EFFDNGOE_01062 5.4e-19 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EFFDNGOE_01063 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EFFDNGOE_01064 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
EFFDNGOE_01065 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
EFFDNGOE_01066 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
EFFDNGOE_01067 1.1e-158 rssA S Phospholipase, patatin family
EFFDNGOE_01068 1.9e-59 estA E GDSL-like protein
EFFDNGOE_01069 5.5e-34 estA E Lysophospholipase L1 and related esterases
EFFDNGOE_01070 8.5e-290 S unusual protein kinase
EFFDNGOE_01071 4.9e-39 S granule-associated protein
EFFDNGOE_01072 3.2e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFFDNGOE_01073 2.6e-97 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFFDNGOE_01074 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFFDNGOE_01075 1.1e-198 S hmm pf01594
EFFDNGOE_01076 2.5e-99 G Belongs to the phosphoglycerate mutase family
EFFDNGOE_01077 7.2e-104 G Belongs to the phosphoglycerate mutase family
EFFDNGOE_01078 1.1e-95 pgm G Belongs to the phosphoglycerate mutase family
EFFDNGOE_01079 5.6e-65 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
EFFDNGOE_01080 5.4e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EFFDNGOE_01081 2.2e-94 V VanZ like family
EFFDNGOE_01082 3.1e-37 L Transposase
EFFDNGOE_01083 6.2e-112 L the current gene model (or a revised gene model) may contain a frame shift
EFFDNGOE_01084 6.4e-33 cpsJ S Glycosyltransferase like family 2
EFFDNGOE_01085 7.8e-16
EFFDNGOE_01086 6.5e-72 M Glycosyltransferase sugar-binding region containing DXD motif
EFFDNGOE_01087 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
EFFDNGOE_01088 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
EFFDNGOE_01089 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
EFFDNGOE_01090 3.3e-37 L transposase activity
EFFDNGOE_01091 1.1e-60 L Integrase core domain
EFFDNGOE_01092 3.2e-71 L COG2801 Transposase and inactivated derivatives
EFFDNGOE_01093 1.1e-235 cps1C S Polysaccharide biosynthesis protein
EFFDNGOE_01094 1.3e-23 L Transposase
EFFDNGOE_01095 1.3e-199 L Transposase
EFFDNGOE_01096 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
EFFDNGOE_01097 8.8e-139 L Integrase core domain
EFFDNGOE_01098 2.2e-22 L Transposase
EFFDNGOE_01099 9.7e-23 rgpAc GT4 M group 1 family protein
EFFDNGOE_01100 1.7e-249 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
EFFDNGOE_01101 1.4e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
EFFDNGOE_01102 1.1e-103 cps4C M biosynthesis protein
EFFDNGOE_01103 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
EFFDNGOE_01104 4.2e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
EFFDNGOE_01105 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
EFFDNGOE_01106 4.1e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
EFFDNGOE_01107 2.2e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
EFFDNGOE_01108 6.1e-36 clcA_2 P chloride channel
EFFDNGOE_01109 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EFFDNGOE_01110 9.6e-47 S Protein of unknown function (DUF1697)
EFFDNGOE_01111 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EFFDNGOE_01112 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EFFDNGOE_01114 1.5e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
EFFDNGOE_01115 2.4e-275 pepV 3.5.1.18 E Dipeptidase
EFFDNGOE_01116 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EFFDNGOE_01117 1.7e-47 XK27_03610 K Gnat family
EFFDNGOE_01118 1.6e-24 L Transposase
EFFDNGOE_01119 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EFFDNGOE_01120 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EFFDNGOE_01121 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EFFDNGOE_01122 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EFFDNGOE_01123 3.9e-15 M LysM domain
EFFDNGOE_01124 2.9e-90 ebsA S Family of unknown function (DUF5322)
EFFDNGOE_01125 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EFFDNGOE_01126 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EFFDNGOE_01127 4.9e-224 G COG0457 FOG TPR repeat
EFFDNGOE_01128 1.3e-178 yubA S permease
EFFDNGOE_01129 1.7e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
EFFDNGOE_01130 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EFFDNGOE_01131 2.5e-124 ftsE D cell division ATP-binding protein FtsE
EFFDNGOE_01132 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EFFDNGOE_01133 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EFFDNGOE_01134 9.2e-183 yjjH S Calcineurin-like phosphoesterase
EFFDNGOE_01135 1.7e-134 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EFFDNGOE_01136 0.0 pacL 3.6.3.8 P cation transport ATPase
EFFDNGOE_01137 2.6e-67 ywiB S Domain of unknown function (DUF1934)
EFFDNGOE_01138 8.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
EFFDNGOE_01139 4.6e-146 yidA S hydrolases of the HAD superfamily
EFFDNGOE_01140 5.3e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
EFFDNGOE_01141 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
EFFDNGOE_01142 1.5e-247 vicK 2.7.13.3 T Histidine kinase
EFFDNGOE_01143 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFFDNGOE_01144 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
EFFDNGOE_01145 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EFFDNGOE_01146 8e-115 gltJ P ABC transporter (Permease
EFFDNGOE_01147 4.2e-110 tcyB_2 P ABC transporter (permease)
EFFDNGOE_01148 2.4e-124 endA F DNA RNA non-specific endonuclease
EFFDNGOE_01149 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
EFFDNGOE_01150 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFFDNGOE_01152 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EFFDNGOE_01153 5.9e-26 G Domain of unknown function (DUF4832)
EFFDNGOE_01154 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EFFDNGOE_01155 1.6e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EFFDNGOE_01156 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EFFDNGOE_01157 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
EFFDNGOE_01158 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EFFDNGOE_01159 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
EFFDNGOE_01160 5.8e-80
EFFDNGOE_01162 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EFFDNGOE_01163 3.5e-206 XK27_05110 P Chloride transporter ClC family
EFFDNGOE_01164 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
EFFDNGOE_01165 1.3e-282 clcA P Chloride transporter, ClC family
EFFDNGOE_01166 2.3e-75 fld C Flavodoxin
EFFDNGOE_01167 3.3e-14 XK27_08880
EFFDNGOE_01168 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
EFFDNGOE_01169 1.6e-151 estA CE1 S Putative esterase
EFFDNGOE_01170 3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EFFDNGOE_01171 4.4e-135 XK27_08845 S abc transporter atp-binding protein
EFFDNGOE_01172 2.2e-146 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
EFFDNGOE_01173 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
EFFDNGOE_01174 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
EFFDNGOE_01175 6.1e-28 Q the current gene model (or a revised gene model) may contain a frame shift
EFFDNGOE_01178 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EFFDNGOE_01179 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EFFDNGOE_01180 0.0 dnaE 2.7.7.7 L DNA polymerase
EFFDNGOE_01181 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
EFFDNGOE_01182 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EFFDNGOE_01183 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EFFDNGOE_01184 2.5e-43 ysdA L Membrane
EFFDNGOE_01185 7.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EFFDNGOE_01186 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EFFDNGOE_01187 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EFFDNGOE_01188 1.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
EFFDNGOE_01190 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EFFDNGOE_01191 1.7e-83 ypmS S Protein conserved in bacteria
EFFDNGOE_01192 3.9e-143 ypmR E lipolytic protein G-D-S-L family
EFFDNGOE_01193 1e-148 DegV S DegV family
EFFDNGOE_01194 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
EFFDNGOE_01195 3.7e-73 argR K Regulates arginine biosynthesis genes
EFFDNGOE_01196 4.7e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EFFDNGOE_01197 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EFFDNGOE_01198 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
EFFDNGOE_01199 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EFFDNGOE_01202 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EFFDNGOE_01203 2.9e-125 dnaD
EFFDNGOE_01204 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EFFDNGOE_01205 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EFFDNGOE_01206 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
EFFDNGOE_01207 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EFFDNGOE_01208 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EFFDNGOE_01209 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EFFDNGOE_01210 7.8e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EFFDNGOE_01211 5.6e-240 rodA D Belongs to the SEDS family
EFFDNGOE_01212 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
EFFDNGOE_01213 1.2e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EFFDNGOE_01214 1e-108 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EFFDNGOE_01215 8.3e-21 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EFFDNGOE_01216 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EFFDNGOE_01217 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EFFDNGOE_01218 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EFFDNGOE_01219 2.6e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EFFDNGOE_01220 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EFFDNGOE_01221 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EFFDNGOE_01222 1.6e-154 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EFFDNGOE_01223 1.5e-29 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EFFDNGOE_01225 2.1e-120 L Transposase
EFFDNGOE_01226 3.2e-89 L Transposase
EFFDNGOE_01227 8.2e-26 L Integrase core domain protein
EFFDNGOE_01228 1.6e-55 L transposition
EFFDNGOE_01229 8.2e-22 L Transposase
EFFDNGOE_01230 5.2e-36 L transposase activity
EFFDNGOE_01231 1.3e-22 XK27_08085
EFFDNGOE_01232 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EFFDNGOE_01233 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EFFDNGOE_01234 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
EFFDNGOE_01235 1.1e-121 ylfI S tigr01906
EFFDNGOE_01236 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EFFDNGOE_01237 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
EFFDNGOE_01238 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
EFFDNGOE_01241 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EFFDNGOE_01242 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EFFDNGOE_01243 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EFFDNGOE_01244 2.1e-207 yurR 1.4.5.1 E oxidoreductase
EFFDNGOE_01245 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
EFFDNGOE_01246 8.1e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EFFDNGOE_01247 7.9e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
EFFDNGOE_01248 1.3e-70 gtrA S GtrA-like protein
EFFDNGOE_01249 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EFFDNGOE_01250 2.3e-168 ybbR S Protein conserved in bacteria
EFFDNGOE_01251 1.2e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EFFDNGOE_01252 1.1e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
EFFDNGOE_01253 8.7e-150 cobQ S glutamine amidotransferase
EFFDNGOE_01254 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EFFDNGOE_01255 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
EFFDNGOE_01256 6.3e-13 MA20_06245 S yiaA/B two helix domain
EFFDNGOE_01258 0.0 uup S abc transporter atp-binding protein
EFFDNGOE_01259 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
EFFDNGOE_01260 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
EFFDNGOE_01261 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EFFDNGOE_01262 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
EFFDNGOE_01263 1.6e-249 L Transposase
EFFDNGOE_01264 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EFFDNGOE_01265 7.9e-39 ptsH G phosphocarrier protein Hpr
EFFDNGOE_01266 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
EFFDNGOE_01267 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
EFFDNGOE_01268 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EFFDNGOE_01269 2.2e-34 nrdH O Glutaredoxin
EFFDNGOE_01270 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFFDNGOE_01271 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EFFDNGOE_01273 4.2e-71 L Transposase (IS116 IS110 IS902 family)
EFFDNGOE_01274 8.8e-60 L Transposase (IS116 IS110 IS902 family)
EFFDNGOE_01275 5.3e-165 ypuA S secreted protein
EFFDNGOE_01276 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
EFFDNGOE_01277 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
EFFDNGOE_01278 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFFDNGOE_01279 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EFFDNGOE_01280 3.4e-258 noxE P NADH oxidase
EFFDNGOE_01281 1.9e-294 yfmM S abc transporter atp-binding protein
EFFDNGOE_01282 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
EFFDNGOE_01283 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EFFDNGOE_01284 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EFFDNGOE_01285 2e-86 S ECF-type riboflavin transporter, S component
EFFDNGOE_01287 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EFFDNGOE_01288 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
EFFDNGOE_01291 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EFFDNGOE_01292 4.6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFFDNGOE_01293 1.2e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EFFDNGOE_01294 0.0 smc D Required for chromosome condensation and partitioning
EFFDNGOE_01295 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EFFDNGOE_01296 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EFFDNGOE_01297 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EFFDNGOE_01298 2.4e-92 pat 2.3.1.183 M acetyltransferase
EFFDNGOE_01299 3e-13
EFFDNGOE_01300 6.3e-23
EFFDNGOE_01301 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EFFDNGOE_01302 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EFFDNGOE_01303 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
EFFDNGOE_01304 1.2e-62 bioY S biotin transmembrane transporter activity
EFFDNGOE_01305 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
EFFDNGOE_01306 1.5e-138 proV E abc transporter atp-binding protein
EFFDNGOE_01307 7.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
EFFDNGOE_01308 3e-111 proWZ P ABC transporter (Permease
EFFDNGOE_01309 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
EFFDNGOE_01310 1.4e-133 S Protein of unknown function (DUF917)
EFFDNGOE_01311 1.2e-48 S Protein of unknown function (DUF917)
EFFDNGOE_01312 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EFFDNGOE_01313 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
EFFDNGOE_01314 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFFDNGOE_01315 1.5e-192 desK 2.7.13.3 T Histidine kinase
EFFDNGOE_01316 1.4e-133 yvfS V ABC-2 type transporter
EFFDNGOE_01317 8.7e-159 XK27_09825 V abc transporter atp-binding protein
EFFDNGOE_01321 6.6e-213 EGP Major facilitator Superfamily
EFFDNGOE_01322 7.2e-286 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
EFFDNGOE_01323 1.6e-140 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
EFFDNGOE_01324 4.6e-152 mutR K Transcriptional activator, Rgg GadR MutR family
EFFDNGOE_01325 4.6e-42 3.6.1.55 F NUDIX domain
EFFDNGOE_01326 1.4e-220 L Transposase
EFFDNGOE_01328 3.7e-122 S An automated process has identified a potential problem with this gene model
EFFDNGOE_01329 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
EFFDNGOE_01330 1.4e-15 liaI KT membrane
EFFDNGOE_01331 2.6e-30 liaI KT membrane
EFFDNGOE_01332 6.1e-93 XK27_05000 S metal cluster binding
EFFDNGOE_01333 0.0 V ABC transporter (permease)
EFFDNGOE_01334 1.9e-133 macB2 V ABC transporter, ATP-binding protein
EFFDNGOE_01335 6.2e-166 T Histidine kinase
EFFDNGOE_01336 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EFFDNGOE_01337 3.2e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EFFDNGOE_01339 2.1e-192 pbuX F xanthine permease
EFFDNGOE_01340 4.5e-247 norM V Multidrug efflux pump
EFFDNGOE_01341 2.2e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EFFDNGOE_01342 1.7e-235 brnQ E Component of the transport system for branched-chain amino acids
EFFDNGOE_01343 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
EFFDNGOE_01344 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
EFFDNGOE_01345 4.8e-25 csbD K CsbD-like
EFFDNGOE_01347 4e-227 yfnA E amino acid
EFFDNGOE_01348 5.1e-110 XK27_02070 S nitroreductase
EFFDNGOE_01349 9.5e-150 1.13.11.2 S glyoxalase
EFFDNGOE_01350 5.6e-77 ywnA K Transcriptional regulator
EFFDNGOE_01351 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
EFFDNGOE_01352 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EFFDNGOE_01353 1.4e-110 drgA C Nitroreductase
EFFDNGOE_01354 3e-102 yoaK S Protein of unknown function (DUF1275)
EFFDNGOE_01355 6.8e-161 yvgN C reductase
EFFDNGOE_01356 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EFFDNGOE_01357 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
EFFDNGOE_01359 1.1e-37 BP1961 P nitric oxide dioxygenase activity
EFFDNGOE_01360 1.4e-54 K response regulator
EFFDNGOE_01361 9.3e-72 S Signal peptide protein, YSIRK family
EFFDNGOE_01363 4.5e-61
EFFDNGOE_01364 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFFDNGOE_01365 1e-137
EFFDNGOE_01366 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
EFFDNGOE_01367 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
EFFDNGOE_01368 5.8e-109 MA20_06410 E LysE type translocator
EFFDNGOE_01369 5.6e-08
EFFDNGOE_01370 2.7e-09
EFFDNGOE_01371 0.0 M family 8
EFFDNGOE_01373 5e-161 hrtB V MacB-like periplasmic core domain
EFFDNGOE_01374 1.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
EFFDNGOE_01375 1.1e-151 V MatE
EFFDNGOE_01377 3.9e-110 C Fe-S oxidoreductases
EFFDNGOE_01378 1.2e-176 EGP Major Facilitator Superfamily
EFFDNGOE_01379 5.5e-258 I radical SAM domain protein
EFFDNGOE_01381 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EFFDNGOE_01382 1.4e-150 L Integrase core domain protein
EFFDNGOE_01383 1.8e-87 L transposase activity
EFFDNGOE_01385 1.4e-84
EFFDNGOE_01386 0.0 sbcC L ATPase involved in DNA repair
EFFDNGOE_01387 1.3e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EFFDNGOE_01388 0.0 lacL 3.2.1.23 G -beta-galactosidase
EFFDNGOE_01389 0.0 lacS G transporter
EFFDNGOE_01390 2.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EFFDNGOE_01391 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EFFDNGOE_01392 1.3e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EFFDNGOE_01393 3.7e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EFFDNGOE_01394 2.3e-184 galR K Transcriptional regulator
EFFDNGOE_01395 2.7e-08 L Integrase core domain protein
EFFDNGOE_01396 1.2e-25 L transposition
EFFDNGOE_01397 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
EFFDNGOE_01398 5.1e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
EFFDNGOE_01399 2.5e-101 V abc transporter atp-binding protein
EFFDNGOE_01400 4.3e-40 V abc transporter atp-binding protein
EFFDNGOE_01401 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
EFFDNGOE_01402 6.4e-62 L Transposase
EFFDNGOE_01403 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFFDNGOE_01404 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFFDNGOE_01405 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EFFDNGOE_01406 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EFFDNGOE_01407 8.6e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EFFDNGOE_01408 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EFFDNGOE_01409 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EFFDNGOE_01412 8.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EFFDNGOE_01413 1.9e-173 vraS 2.7.13.3 T Histidine kinase
EFFDNGOE_01414 9.1e-119 yvqF KT membrane
EFFDNGOE_01415 1.7e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
EFFDNGOE_01416 9e-133 stp 3.1.3.16 T phosphatase
EFFDNGOE_01417 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EFFDNGOE_01418 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EFFDNGOE_01419 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EFFDNGOE_01420 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
EFFDNGOE_01421 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EFFDNGOE_01422 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EFFDNGOE_01423 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
EFFDNGOE_01424 5.3e-147 supH S overlaps another CDS with the same product name
EFFDNGOE_01425 8.6e-63 yvoA_1 K Transcriptional
EFFDNGOE_01426 9.8e-121 skfE V abc transporter atp-binding protein
EFFDNGOE_01427 9e-131 V ATPase activity
EFFDNGOE_01428 4.3e-172 oppF P Belongs to the ABC transporter superfamily
EFFDNGOE_01429 2.2e-204 oppD P Belongs to the ABC transporter superfamily
EFFDNGOE_01430 2.4e-167 amiD P ABC transporter (Permease
EFFDNGOE_01431 1.1e-270 amiC P ABC transporter (Permease
EFFDNGOE_01432 0.0 amiA E ABC transporter, substrate-binding protein, family 5
EFFDNGOE_01433 8.1e-45 L Transposase
EFFDNGOE_01434 4.1e-158 L COG2801 Transposase and inactivated derivatives
EFFDNGOE_01435 1.2e-24 oppF P Belongs to the ABC transporter superfamily
EFFDNGOE_01436 5.5e-23 oppF P Belongs to the ABC transporter superfamily
EFFDNGOE_01437 2e-21 tatD L hydrolase, TatD family'
EFFDNGOE_01438 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
EFFDNGOE_01439 4e-110 L PFAM Integrase catalytic region
EFFDNGOE_01440 9.3e-29 L transposition
EFFDNGOE_01441 1.4e-38 L transposase activity
EFFDNGOE_01442 3.7e-38 L transposase activity
EFFDNGOE_01443 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EFFDNGOE_01444 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EFFDNGOE_01445 1.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EFFDNGOE_01446 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
EFFDNGOE_01447 5.8e-103 yjbK S Adenylate cyclase
EFFDNGOE_01448 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EFFDNGOE_01449 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
EFFDNGOE_01450 9e-59 XK27_04120 S Putative amino acid metabolism
EFFDNGOE_01451 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EFFDNGOE_01452 1.6e-131 puuD T peptidase C26
EFFDNGOE_01453 6.2e-120 radC E Belongs to the UPF0758 family
EFFDNGOE_01454 0.0 rgpF M Rhamnan synthesis protein F
EFFDNGOE_01455 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EFFDNGOE_01456 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EFFDNGOE_01457 1.1e-142 rgpC GM Transport permease protein
EFFDNGOE_01458 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
EFFDNGOE_01459 1.3e-226 rgpA GT4 M Domain of unknown function (DUF1972)
EFFDNGOE_01460 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
EFFDNGOE_01461 2.6e-220 amrA S polysaccharide biosynthetic process
EFFDNGOE_01462 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
EFFDNGOE_01463 7.6e-126 ycbB S Glycosyl transferase family 2
EFFDNGOE_01464 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EFFDNGOE_01465 1.2e-231
EFFDNGOE_01466 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EFFDNGOE_01467 5.4e-251 M Psort location CytoplasmicMembrane, score
EFFDNGOE_01468 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
EFFDNGOE_01469 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EFFDNGOE_01470 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EFFDNGOE_01471 1.1e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EFFDNGOE_01472 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EFFDNGOE_01473 7.9e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
EFFDNGOE_01474 3.4e-200 arcT 2.6.1.1 E Aminotransferase
EFFDNGOE_01475 7.2e-136 ET ABC transporter
EFFDNGOE_01476 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
EFFDNGOE_01477 2.9e-84 mutT 3.6.1.55 F Nudix family
EFFDNGOE_01478 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EFFDNGOE_01480 1.2e-55 V CAAX protease self-immunity
EFFDNGOE_01481 2.6e-32 S CAAX amino terminal protease family protein
EFFDNGOE_01482 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
EFFDNGOE_01483 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
EFFDNGOE_01484 2.4e-16 XK27_00735
EFFDNGOE_01485 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EFFDNGOE_01487 3.6e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EFFDNGOE_01490 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
EFFDNGOE_01491 6.6e-30 ycaO O OsmC-like protein
EFFDNGOE_01493 8.5e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
EFFDNGOE_01495 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
EFFDNGOE_01496 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFFDNGOE_01497 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EFFDNGOE_01498 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EFFDNGOE_01499 7.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
EFFDNGOE_01500 2.8e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EFFDNGOE_01501 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EFFDNGOE_01502 2.6e-109 3.1.3.18 S IA, variant 1
EFFDNGOE_01503 2.2e-117 lrgB M effector of murein hydrolase
EFFDNGOE_01504 2.2e-58 lrgA S Effector of murein hydrolase LrgA
EFFDNGOE_01506 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
EFFDNGOE_01507 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
EFFDNGOE_01508 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EFFDNGOE_01509 3.9e-104 wecD M Acetyltransferase GNAT family
EFFDNGOE_01510 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EFFDNGOE_01511 2.6e-95 GK ROK family
EFFDNGOE_01512 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
EFFDNGOE_01513 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
EFFDNGOE_01514 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
EFFDNGOE_01515 2.3e-206 potD P spermidine putrescine ABC transporter
EFFDNGOE_01516 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
EFFDNGOE_01517 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
EFFDNGOE_01518 6.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EFFDNGOE_01519 7.8e-171 murB 1.3.1.98 M cell wall formation
EFFDNGOE_01520 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EFFDNGOE_01521 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EFFDNGOE_01522 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EFFDNGOE_01523 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EFFDNGOE_01524 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
EFFDNGOE_01525 0.0 ydaO E amino acid
EFFDNGOE_01526 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EFFDNGOE_01527 4.1e-37 ylqC L Belongs to the UPF0109 family
EFFDNGOE_01528 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EFFDNGOE_01529 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
EFFDNGOE_01530 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
EFFDNGOE_01531 2.1e-74 S QueT transporter
EFFDNGOE_01532 1.9e-55 L Transposase
EFFDNGOE_01533 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EFFDNGOE_01534 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EFFDNGOE_01535 3.7e-85 ccl S cog cog4708
EFFDNGOE_01536 7.4e-164 rbn E Belongs to the UPF0761 family
EFFDNGOE_01537 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
EFFDNGOE_01538 3.3e-231 ytoI K transcriptional regulator containing CBS domains
EFFDNGOE_01539 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
EFFDNGOE_01540 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EFFDNGOE_01541 0.0 comEC S Competence protein ComEC
EFFDNGOE_01542 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EFFDNGOE_01543 8.3e-142 plsC 2.3.1.51 I Acyltransferase
EFFDNGOE_01544 1.7e-77 nodB3 G polysaccharide deacetylase
EFFDNGOE_01545 4.1e-22 nodB3 G polysaccharide deacetylase
EFFDNGOE_01546 2.3e-139 yabB 2.1.1.223 L Methyltransferase
EFFDNGOE_01547 1e-41 yazA L endonuclease containing a URI domain
EFFDNGOE_01549 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EFFDNGOE_01550 2.3e-154 corA P CorA-like protein
EFFDNGOE_01551 1.9e-62 yjqA S Bacterial PH domain
EFFDNGOE_01552 7.8e-100 thiT S Thiamine transporter
EFFDNGOE_01553 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EFFDNGOE_01554 1.6e-200 yjbB G Permeases of the major facilitator superfamily
EFFDNGOE_01555 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EFFDNGOE_01556 7.9e-120 ywaF S Integral membrane protein (intg_mem_TP0381)
EFFDNGOE_01557 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EFFDNGOE_01561 1.1e-155 cjaA ET ABC transporter substrate-binding protein
EFFDNGOE_01562 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
EFFDNGOE_01563 3e-106 P ABC transporter (Permease
EFFDNGOE_01564 6e-115 papP P ABC transporter (Permease
EFFDNGOE_01565 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EFFDNGOE_01566 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
EFFDNGOE_01567 0.0 copA 3.6.3.54 P P-type ATPase
EFFDNGOE_01568 2.7e-73 copY K Copper transport repressor, CopY TcrY family
EFFDNGOE_01569 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EFFDNGOE_01570 2.1e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EFFDNGOE_01571 3e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
EFFDNGOE_01572 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EFFDNGOE_01573 1.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EFFDNGOE_01574 2.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
EFFDNGOE_01575 1.5e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EFFDNGOE_01576 1.6e-55
EFFDNGOE_01577 0.0 ctpE P E1-E2 ATPase
EFFDNGOE_01578 6.1e-27
EFFDNGOE_01579 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EFFDNGOE_01580 5.1e-47 L transposase activity
EFFDNGOE_01581 5.3e-119 K transcriptional regulator, MerR family
EFFDNGOE_01582 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
EFFDNGOE_01583 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
EFFDNGOE_01584 7.4e-64 XK27_02560 S cog cog2151
EFFDNGOE_01585 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EFFDNGOE_01586 7.7e-227 ytfP S Flavoprotein
EFFDNGOE_01588 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EFFDNGOE_01589 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
EFFDNGOE_01590 1.6e-183 ecsB U ABC transporter
EFFDNGOE_01591 2.3e-133 ecsA V abc transporter atp-binding protein
EFFDNGOE_01592 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EFFDNGOE_01593 4.8e-11
EFFDNGOE_01594 6.5e-55
EFFDNGOE_01595 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
EFFDNGOE_01596 1.2e-202 ylbM S Belongs to the UPF0348 family
EFFDNGOE_01597 2e-140 yqeM Q Methyltransferase domain protein
EFFDNGOE_01598 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EFFDNGOE_01599 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EFFDNGOE_01600 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EFFDNGOE_01601 3.5e-49 yhbY J RNA-binding protein
EFFDNGOE_01602 2.4e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EFFDNGOE_01603 1.8e-98 yqeG S hydrolase of the HAD superfamily
EFFDNGOE_01604 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EFFDNGOE_01605 4e-59
EFFDNGOE_01606 8.7e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFFDNGOE_01607 1.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EFFDNGOE_01608 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EFFDNGOE_01609 9.8e-25 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
EFFDNGOE_01610 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
EFFDNGOE_01611 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFFDNGOE_01612 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EFFDNGOE_01613 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EFFDNGOE_01614 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
EFFDNGOE_01615 3.4e-100 pncA Q isochorismatase
EFFDNGOE_01616 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EFFDNGOE_01617 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
EFFDNGOE_01618 2.4e-75 XK27_03180 T universal stress protein
EFFDNGOE_01621 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EFFDNGOE_01622 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
EFFDNGOE_01623 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
EFFDNGOE_01624 0.0 yjcE P NhaP-type Na H and K H antiporters
EFFDNGOE_01626 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
EFFDNGOE_01627 1.3e-184 yhcC S radical SAM protein
EFFDNGOE_01628 8.4e-196 ylbL T Belongs to the peptidase S16 family
EFFDNGOE_01629 2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EFFDNGOE_01630 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
EFFDNGOE_01631 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EFFDNGOE_01632 6.1e-08 S Protein of unknown function (DUF4059)
EFFDNGOE_01633 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
EFFDNGOE_01634 1.4e-159 yxeN P ABC transporter (Permease
EFFDNGOE_01635 8.8e-153 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EFFDNGOE_01637 1.3e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EFFDNGOE_01638 0.0 pflB 2.3.1.54 C formate acetyltransferase'
EFFDNGOE_01639 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
EFFDNGOE_01640 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EFFDNGOE_01641 7.2e-46 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
EFFDNGOE_01642 1.4e-33 D nuclear chromosome segregation
EFFDNGOE_01643 1.5e-127 ybbM S transport system, permease component
EFFDNGOE_01644 4.4e-115 ybbL S abc transporter atp-binding protein
EFFDNGOE_01645 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
EFFDNGOE_01646 4.6e-140 cppA E CppA N-terminal
EFFDNGOE_01647 5e-44 V CAAX protease self-immunity
EFFDNGOE_01648 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EFFDNGOE_01649 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EFFDNGOE_01652 3e-47 spiA K sequence-specific DNA binding
EFFDNGOE_01653 2.9e-28 blpT
EFFDNGOE_01654 6.7e-98 blpT
EFFDNGOE_01655 2e-40 L Transposase
EFFDNGOE_01656 1.9e-66 L Transposase
EFFDNGOE_01657 5.2e-164 L integrase core domain
EFFDNGOE_01662 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
EFFDNGOE_01665 4.4e-132 agrA KT phosphorelay signal transduction system
EFFDNGOE_01666 3e-235 blpH 2.7.13.3 T protein histidine kinase activity
EFFDNGOE_01668 4e-235 mesE M Transport protein ComB
EFFDNGOE_01669 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EFFDNGOE_01670 0.0 mdlB V abc transporter atp-binding protein
EFFDNGOE_01671 0.0 mdlA V abc transporter atp-binding protein
EFFDNGOE_01673 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
EFFDNGOE_01674 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EFFDNGOE_01675 2.4e-66 yutD J protein conserved in bacteria
EFFDNGOE_01676 4.8e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EFFDNGOE_01678 1.1e-250 L Transposase
EFFDNGOE_01679 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EFFDNGOE_01680 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EFFDNGOE_01681 0.0 ftsI 3.4.16.4 M penicillin-binding protein
EFFDNGOE_01682 8.1e-46 ftsL D cell division protein FtsL
EFFDNGOE_01683 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EFFDNGOE_01684 2.2e-85
EFFDNGOE_01685 3.4e-58
EFFDNGOE_01686 2.8e-21 yhaI J Protein of unknown function (DUF805)
EFFDNGOE_01687 4.5e-18 D nuclear chromosome segregation
EFFDNGOE_01688 6.9e-210 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EFFDNGOE_01689 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EFFDNGOE_01690 9.2e-284 XK27_00765
EFFDNGOE_01691 2.1e-129 ecsA_2 V abc transporter atp-binding protein
EFFDNGOE_01692 9.3e-122 S Protein of unknown function (DUF554)
EFFDNGOE_01693 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EFFDNGOE_01694 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EFFDNGOE_01695 3.4e-57 liaI S membrane
EFFDNGOE_01696 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
EFFDNGOE_01697 8.5e-68 KT response to antibiotic
EFFDNGOE_01698 3.5e-17 KT response to antibiotic
EFFDNGOE_01699 1.6e-79 yebC M Membrane
EFFDNGOE_01700 2.9e-18 yebC M Membrane
EFFDNGOE_01701 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
EFFDNGOE_01702 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EFFDNGOE_01703 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EFFDNGOE_01704 1.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EFFDNGOE_01705 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EFFDNGOE_01706 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EFFDNGOE_01707 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EFFDNGOE_01708 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EFFDNGOE_01710 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
EFFDNGOE_01711 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
EFFDNGOE_01712 0.0 scrA 2.7.1.211 G pts system
EFFDNGOE_01713 4.1e-291 scrB 3.2.1.26 GH32 G invertase
EFFDNGOE_01714 1.7e-179 scrR K Transcriptional
EFFDNGOE_01715 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EFFDNGOE_01716 3.4e-62 yqhY S protein conserved in bacteria
EFFDNGOE_01717 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EFFDNGOE_01718 1.1e-83 comEB 3.5.4.12 F ComE operon protein 2
EFFDNGOE_01719 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
EFFDNGOE_01722 7.7e-11 V 'abc transporter, ATP-binding protein
EFFDNGOE_01723 1.1e-21 V 'abc transporter, ATP-binding protein
EFFDNGOE_01726 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EFFDNGOE_01727 2e-169 corA P COG0598 Mg2 and Co2 transporters
EFFDNGOE_01728 3.1e-124 XK27_01040 S Pfam PF06570
EFFDNGOE_01730 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EFFDNGOE_01731 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EFFDNGOE_01732 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
EFFDNGOE_01733 3.6e-41 XK27_05745
EFFDNGOE_01734 2.5e-230 mutY L A G-specific adenine glycosylase
EFFDNGOE_01739 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EFFDNGOE_01740 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EFFDNGOE_01741 1e-93 cvpA S toxin biosynthetic process
EFFDNGOE_01742 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EFFDNGOE_01743 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EFFDNGOE_01744 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EFFDNGOE_01745 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EFFDNGOE_01746 8.8e-48 azlD E branched-chain amino acid
EFFDNGOE_01747 1.8e-114 azlC E AzlC protein
EFFDNGOE_01748 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EFFDNGOE_01749 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EFFDNGOE_01750 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
EFFDNGOE_01751 2.5e-33 ykzG S Belongs to the UPF0356 family
EFFDNGOE_01752 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EFFDNGOE_01753 2.7e-40 pscB M CHAP domain protein
EFFDNGOE_01754 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
EFFDNGOE_01755 8.5e-63 glnR K Transcriptional regulator
EFFDNGOE_01756 1.3e-87 S Fusaric acid resistance protein-like
EFFDNGOE_01757 1.5e-12
EFFDNGOE_01758 3.1e-30
EFFDNGOE_01759 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EFFDNGOE_01760 6e-86 L Transposase
EFFDNGOE_01761 1.6e-55 L transposition
EFFDNGOE_01762 1.9e-86 L Integrase core domain protein
EFFDNGOE_01763 1.8e-187 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EFFDNGOE_01764 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EFFDNGOE_01765 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EFFDNGOE_01766 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EFFDNGOE_01767 5.3e-142 purR 2.4.2.7 F operon repressor
EFFDNGOE_01768 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
EFFDNGOE_01769 6.9e-173 rmuC S RmuC domain protein
EFFDNGOE_01770 2.4e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
EFFDNGOE_01771 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EFFDNGOE_01772 4.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EFFDNGOE_01774 6.2e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EFFDNGOE_01775 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EFFDNGOE_01776 1.6e-143 tatD L Hydrolase, tatd
EFFDNGOE_01777 1.1e-50 trxA O Belongs to the thioredoxin family
EFFDNGOE_01778 1.9e-141 S Macro domain protein
EFFDNGOE_01779 2e-09 L thioesterase
EFFDNGOE_01780 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
EFFDNGOE_01784 6.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EFFDNGOE_01785 1.1e-83 L Transposase
EFFDNGOE_01786 1e-13 rpmH J Ribosomal protein L34
EFFDNGOE_01787 2e-186 jag S RNA-binding protein
EFFDNGOE_01788 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFFDNGOE_01789 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EFFDNGOE_01790 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
EFFDNGOE_01791 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EFFDNGOE_01792 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EFFDNGOE_01793 6.7e-81 amiA E transmembrane transport
EFFDNGOE_01794 7.3e-69 amiA E transmembrane transport
EFFDNGOE_01795 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EFFDNGOE_01796 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EFFDNGOE_01797 9.2e-51 S Protein of unknown function (DUF3397)
EFFDNGOE_01798 1.2e-165 L integrase core domain
EFFDNGOE_01799 3.9e-122 L Transposase
EFFDNGOE_01800 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
EFFDNGOE_01801 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
EFFDNGOE_01802 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
EFFDNGOE_01803 1.8e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EFFDNGOE_01804 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EFFDNGOE_01805 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
EFFDNGOE_01806 6.2e-76 XK27_09620 S reductase
EFFDNGOE_01807 1.5e-220 XK27_09615 C reductase
EFFDNGOE_01808 2.5e-116 fnt P Formate nitrite transporter
EFFDNGOE_01809 1.3e-83 XK27_08585 S Psort location CytoplasmicMembrane, score
EFFDNGOE_01810 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EFFDNGOE_01811 1.6e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EFFDNGOE_01812 7.5e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
EFFDNGOE_01813 8.5e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EFFDNGOE_01814 1.3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EFFDNGOE_01815 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EFFDNGOE_01816 1.9e-46 S glycolate biosynthetic process
EFFDNGOE_01817 1.5e-64 S phosphatase activity
EFFDNGOE_01818 4.1e-158 rrmA 2.1.1.187 Q methyltransferase
EFFDNGOE_01821 1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EFFDNGOE_01822 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EFFDNGOE_01823 1.9e-36 yeeD O sulfur carrier activity
EFFDNGOE_01824 2e-109 yeeE S Sulphur transport
EFFDNGOE_01825 2.6e-68 yeeE S Sulphur transport
EFFDNGOE_01826 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EFFDNGOE_01827 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EFFDNGOE_01828 4.1e-09 S Domain of unknown function (DUF4651)
EFFDNGOE_01829 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EFFDNGOE_01830 4.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EFFDNGOE_01831 1.6e-249 L Transposase
EFFDNGOE_01832 8.7e-111 S CAAX amino terminal protease family protein
EFFDNGOE_01834 1.1e-66 V CAAX protease self-immunity
EFFDNGOE_01835 2.6e-26 lanR K sequence-specific DNA binding
EFFDNGOE_01836 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EFFDNGOE_01837 1.1e-175 ytxK 2.1.1.72 L DNA methylase
EFFDNGOE_01838 2e-12 comGF U Putative Competence protein ComGF
EFFDNGOE_01839 1.5e-71 comGF U Competence protein ComGF
EFFDNGOE_01840 1.4e-15 NU Type II secretory pathway pseudopilin
EFFDNGOE_01841 1.8e-57 cglD NU Competence protein
EFFDNGOE_01842 8.5e-43 comGC U Required for transformation and DNA binding
EFFDNGOE_01843 9.1e-156 cglB U protein transport across the cell outer membrane
EFFDNGOE_01844 6e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EFFDNGOE_01845 2.9e-68 S cog cog4699
EFFDNGOE_01846 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFFDNGOE_01847 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFFDNGOE_01848 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EFFDNGOE_01849 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EFFDNGOE_01850 1.5e-194 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EFFDNGOE_01851 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
EFFDNGOE_01852 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
EFFDNGOE_01853 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EFFDNGOE_01854 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
EFFDNGOE_01855 1.8e-57 asp S cog cog1302
EFFDNGOE_01856 3.2e-226 norN V Mate efflux family protein
EFFDNGOE_01857 1.2e-277 thrC 4.2.3.1 E Threonine synthase
EFFDNGOE_01858 6.1e-64 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EFFDNGOE_01859 4.1e-22 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EFFDNGOE_01860 7.3e-74 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EFFDNGOE_01861 1.2e-133 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EFFDNGOE_01862 2.1e-52 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
EFFDNGOE_01863 0.0 pepO 3.4.24.71 O Peptidase family M13
EFFDNGOE_01864 1.5e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EFFDNGOE_01865 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EFFDNGOE_01866 1.4e-54 treB 2.7.1.201 G PTS System
EFFDNGOE_01867 5.8e-21 treR K DNA-binding transcription factor activity
EFFDNGOE_01868 1.2e-85 treR K trehalose operon
EFFDNGOE_01869 3.3e-95 ywlG S Belongs to the UPF0340 family
EFFDNGOE_01872 2e-35 L PFAM Integrase, catalytic core
EFFDNGOE_01873 2e-94 L PFAM Integrase, catalytic core
EFFDNGOE_01874 3.3e-46 K Putative DNA-binding domain
EFFDNGOE_01875 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
EFFDNGOE_01876 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EFFDNGOE_01877 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
EFFDNGOE_01882 1e-39
EFFDNGOE_01883 6.5e-31
EFFDNGOE_01884 5e-31 S Hypothetical protein (DUF2513)
EFFDNGOE_01885 7.7e-13
EFFDNGOE_01887 5.7e-217 S MvaI/BcnI restriction endonuclease family
EFFDNGOE_01889 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
EFFDNGOE_01890 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
EFFDNGOE_01892 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
EFFDNGOE_01893 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
EFFDNGOE_01894 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
EFFDNGOE_01895 3.3e-09 L PFAM Integrase, catalytic core
EFFDNGOE_01896 1.8e-111 L PFAM Integrase, catalytic core
EFFDNGOE_01897 3.3e-62 rplQ J ribosomal protein l17
EFFDNGOE_01898 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EFFDNGOE_01899 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EFFDNGOE_01900 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EFFDNGOE_01901 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EFFDNGOE_01902 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EFFDNGOE_01903 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EFFDNGOE_01904 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EFFDNGOE_01905 4.4e-58 rplO J binds to the 23S rRNA
EFFDNGOE_01906 2.5e-23 rpmD J ribosomal protein l30
EFFDNGOE_01907 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EFFDNGOE_01908 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EFFDNGOE_01909 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EFFDNGOE_01910 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EFFDNGOE_01911 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EFFDNGOE_01912 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EFFDNGOE_01913 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EFFDNGOE_01914 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EFFDNGOE_01915 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EFFDNGOE_01916 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
EFFDNGOE_01917 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EFFDNGOE_01918 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EFFDNGOE_01919 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EFFDNGOE_01920 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EFFDNGOE_01921 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EFFDNGOE_01922 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EFFDNGOE_01923 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
EFFDNGOE_01924 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EFFDNGOE_01925 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
EFFDNGOE_01926 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EFFDNGOE_01927 0.0 XK27_09800 I Acyltransferase
EFFDNGOE_01928 1.7e-35 XK27_09805 S MORN repeat protein
EFFDNGOE_01929 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EFFDNGOE_01930 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EFFDNGOE_01931 1.8e-50 adk 2.7.4.3 F topology modulation protein
EFFDNGOE_01932 7.6e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EFFDNGOE_01933 9.7e-30 S Domain of unknown function (DUF4649)
EFFDNGOE_01934 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EFFDNGOE_01935 3.2e-56 Z012_04635 K sequence-specific DNA binding
EFFDNGOE_01936 1.4e-59 Z012_04635 K sequence-specific DNA binding
EFFDNGOE_01938 7.5e-109 C Radical SAM
EFFDNGOE_01939 3e-104 C Radical SAM
EFFDNGOE_01940 3.9e-287 V ABC transporter transmembrane region
EFFDNGOE_01941 1e-155 L Replication initiation factor
EFFDNGOE_01942 1.9e-18 S Domain of unknown function (DUF3173)
EFFDNGOE_01943 1.7e-215 int L Belongs to the 'phage' integrase family
EFFDNGOE_01945 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
EFFDNGOE_01946 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EFFDNGOE_01947 2.8e-44 yrzL S Belongs to the UPF0297 family
EFFDNGOE_01948 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EFFDNGOE_01949 4.2e-44 yrzB S Belongs to the UPF0473 family
EFFDNGOE_01950 2.8e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
EFFDNGOE_01951 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EFFDNGOE_01952 7.5e-14
EFFDNGOE_01953 2.6e-91 XK27_10930 K acetyltransferase
EFFDNGOE_01954 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EFFDNGOE_01955 1.8e-147 yaaA S Belongs to the UPF0246 family
EFFDNGOE_01956 9.3e-167 XK27_01785 S cog cog1284
EFFDNGOE_01957 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EFFDNGOE_01959 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
EFFDNGOE_01960 1.4e-53 metE 2.1.1.14 E Methionine synthase
EFFDNGOE_01961 5.2e-55 metE 2.1.1.14 E Methionine synthase
EFFDNGOE_01962 1.4e-36 metE 2.1.1.14 E Methionine synthase
EFFDNGOE_01963 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EFFDNGOE_01964 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EFFDNGOE_01965 2.4e-28
EFFDNGOE_01966 0.0 V Type II restriction enzyme, methylase subunits
EFFDNGOE_01967 3.2e-10 S Sigma-70, region 4
EFFDNGOE_01968 1.7e-35
EFFDNGOE_01969 1.5e-160 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EFFDNGOE_01970 2e-20
EFFDNGOE_01971 2.1e-82 S Plasmid replication protein
EFFDNGOE_01972 5.9e-20 S MerR HTH family regulatory protein
EFFDNGOE_01973 5.1e-184 sip L Belongs to the 'phage' integrase family
EFFDNGOE_01976 1.5e-49 yegS 2.7.1.107 I lipid kinase activity
EFFDNGOE_01977 2.7e-95 S Hydrophobic domain protein
EFFDNGOE_01979 3.7e-27 S Membrane
EFFDNGOE_01980 9.1e-101
EFFDNGOE_01981 1.8e-23 S Small integral membrane protein
EFFDNGOE_01982 3.1e-85 M Protein conserved in bacteria
EFFDNGOE_01983 1.1e-11 K CsbD-like
EFFDNGOE_01984 3.4e-13 nudL L hydrolase
EFFDNGOE_01985 4e-19 K negative regulation of transcription, DNA-templated
EFFDNGOE_01986 1.7e-23 K negative regulation of transcription, DNA-templated
EFFDNGOE_01988 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
EFFDNGOE_01989 1.2e-87 S Putative adhesin
EFFDNGOE_01990 3.9e-161 XK27_06930 V domain protein
EFFDNGOE_01991 6.4e-96 XK27_06935 K transcriptional regulator
EFFDNGOE_01992 4.8e-55 ypaA M Membrane
EFFDNGOE_01993 2.7e-08
EFFDNGOE_01994 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EFFDNGOE_01995 8.2e-48 veg S Biofilm formation stimulator VEG
EFFDNGOE_01996 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EFFDNGOE_01997 3.9e-70 rplI J binds to the 23S rRNA
EFFDNGOE_01998 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EFFDNGOE_01999 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EFFDNGOE_02000 1.5e-77 F NUDIX domain
EFFDNGOE_02001 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EFFDNGOE_02002 0.0 S Bacterial membrane protein, YfhO
EFFDNGOE_02003 1.7e-63 isaA GH23 M Immunodominant staphylococcal antigen A
EFFDNGOE_02004 5.3e-85 lytE M LysM domain protein
EFFDNGOE_02005 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFFDNGOE_02006 2e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFFDNGOE_02007 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EFFDNGOE_02008 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EFFDNGOE_02009 6.3e-138 ymfM S sequence-specific DNA binding
EFFDNGOE_02010 1.2e-241 ymfH S Peptidase M16
EFFDNGOE_02011 1.3e-156 ymfF S Peptidase M16
EFFDNGOE_02012 1.7e-66 ymfF S Peptidase M16
EFFDNGOE_02013 1.6e-45 yaaA S S4 domain protein YaaA
EFFDNGOE_02014 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EFFDNGOE_02015 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EFFDNGOE_02016 3.1e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EFFDNGOE_02017 4.2e-153 yvjA S membrane
EFFDNGOE_02018 6.7e-306 ybiT S abc transporter atp-binding protein
EFFDNGOE_02019 0.0 XK27_10405 S Bacterial membrane protein YfhO
EFFDNGOE_02023 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
EFFDNGOE_02024 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EFFDNGOE_02025 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
EFFDNGOE_02026 8.5e-134 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)