ORF_ID e_value Gene_name EC_number CAZy COGs Description
IIAEJBAH_00001 1.3e-137 L Transposase
IIAEJBAH_00002 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IIAEJBAH_00003 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IIAEJBAH_00004 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IIAEJBAH_00005 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
IIAEJBAH_00007 2.7e-61 divIC D Septum formation initiator
IIAEJBAH_00008 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IIAEJBAH_00009 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IIAEJBAH_00010 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IIAEJBAH_00011 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IIAEJBAH_00012 1.1e-29 yyzM S Protein conserved in bacteria
IIAEJBAH_00013 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IIAEJBAH_00014 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IIAEJBAH_00015 8.5e-134 parB K Belongs to the ParB family
IIAEJBAH_00016 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IIAEJBAH_00017 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IIAEJBAH_00018 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
IIAEJBAH_00022 0.0 XK27_10405 S Bacterial membrane protein YfhO
IIAEJBAH_00023 6.7e-306 ybiT S abc transporter atp-binding protein
IIAEJBAH_00024 4.2e-153 yvjA S membrane
IIAEJBAH_00025 3.1e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IIAEJBAH_00026 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IIAEJBAH_00027 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IIAEJBAH_00028 1.6e-45 yaaA S S4 domain protein YaaA
IIAEJBAH_00029 1.7e-66 ymfF S Peptidase M16
IIAEJBAH_00030 1.3e-156 ymfF S Peptidase M16
IIAEJBAH_00031 1.2e-241 ymfH S Peptidase M16
IIAEJBAH_00032 6.3e-138 ymfM S sequence-specific DNA binding
IIAEJBAH_00033 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIAEJBAH_00034 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIAEJBAH_00035 2e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIAEJBAH_00036 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIAEJBAH_00037 5.3e-85 lytE M LysM domain protein
IIAEJBAH_00038 1.7e-63 isaA GH23 M Immunodominant staphylococcal antigen A
IIAEJBAH_00039 0.0 S Bacterial membrane protein, YfhO
IIAEJBAH_00040 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IIAEJBAH_00041 1.5e-77 F NUDIX domain
IIAEJBAH_00042 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IIAEJBAH_00043 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IIAEJBAH_00044 3.9e-70 rplI J binds to the 23S rRNA
IIAEJBAH_00045 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IIAEJBAH_00046 8.2e-48 veg S Biofilm formation stimulator VEG
IIAEJBAH_00047 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IIAEJBAH_00048 2.7e-08
IIAEJBAH_00049 4.8e-55 ypaA M Membrane
IIAEJBAH_00050 6.4e-96 XK27_06935 K transcriptional regulator
IIAEJBAH_00051 3.9e-161 XK27_06930 V domain protein
IIAEJBAH_00052 1.2e-87 S Putative adhesin
IIAEJBAH_00053 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
IIAEJBAH_00055 1.7e-23 K negative regulation of transcription, DNA-templated
IIAEJBAH_00056 4e-19 K negative regulation of transcription, DNA-templated
IIAEJBAH_00057 3.4e-13 nudL L hydrolase
IIAEJBAH_00058 1.1e-11 K CsbD-like
IIAEJBAH_00059 3.1e-85 M Protein conserved in bacteria
IIAEJBAH_00060 1.8e-23 S Small integral membrane protein
IIAEJBAH_00061 9.1e-101
IIAEJBAH_00062 3.7e-27 S Membrane
IIAEJBAH_00064 2.7e-95 S Hydrophobic domain protein
IIAEJBAH_00065 1.5e-49 yegS 2.7.1.107 I lipid kinase activity
IIAEJBAH_00068 5.1e-184 sip L Belongs to the 'phage' integrase family
IIAEJBAH_00069 5.9e-20 S MerR HTH family regulatory protein
IIAEJBAH_00070 2.1e-82 S Plasmid replication protein
IIAEJBAH_00071 2e-20
IIAEJBAH_00072 1.5e-160 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IIAEJBAH_00073 1.7e-35
IIAEJBAH_00074 3.2e-10 S Sigma-70, region 4
IIAEJBAH_00075 0.0 V Type II restriction enzyme, methylase subunits
IIAEJBAH_00076 2.4e-28
IIAEJBAH_00077 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IIAEJBAH_00078 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IIAEJBAH_00079 1.4e-36 metE 2.1.1.14 E Methionine synthase
IIAEJBAH_00080 5.2e-55 metE 2.1.1.14 E Methionine synthase
IIAEJBAH_00081 1.4e-53 metE 2.1.1.14 E Methionine synthase
IIAEJBAH_00082 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
IIAEJBAH_00084 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IIAEJBAH_00085 9.3e-167 XK27_01785 S cog cog1284
IIAEJBAH_00086 1.8e-147 yaaA S Belongs to the UPF0246 family
IIAEJBAH_00087 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IIAEJBAH_00088 2.6e-91 XK27_10930 K acetyltransferase
IIAEJBAH_00089 7.5e-14
IIAEJBAH_00090 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IIAEJBAH_00091 2.8e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
IIAEJBAH_00092 4.2e-44 yrzB S Belongs to the UPF0473 family
IIAEJBAH_00093 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IIAEJBAH_00094 2.8e-44 yrzL S Belongs to the UPF0297 family
IIAEJBAH_00095 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IIAEJBAH_00096 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
IIAEJBAH_00098 1.7e-215 int L Belongs to the 'phage' integrase family
IIAEJBAH_00099 1.9e-18 S Domain of unknown function (DUF3173)
IIAEJBAH_00100 5.9e-156 L Replication initiation factor
IIAEJBAH_00101 3.9e-287 V ABC transporter transmembrane region
IIAEJBAH_00102 3e-104 C Radical SAM
IIAEJBAH_00103 7.5e-109 C Radical SAM
IIAEJBAH_00105 1.4e-59 Z012_04635 K sequence-specific DNA binding
IIAEJBAH_00106 3.2e-56 Z012_04635 K sequence-specific DNA binding
IIAEJBAH_00107 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IIAEJBAH_00108 9.7e-30 S Domain of unknown function (DUF4649)
IIAEJBAH_00109 7.6e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIAEJBAH_00110 1.8e-50 adk 2.7.4.3 F topology modulation protein
IIAEJBAH_00111 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IIAEJBAH_00112 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIAEJBAH_00113 1.7e-35 XK27_09805 S MORN repeat protein
IIAEJBAH_00114 0.0 XK27_09800 I Acyltransferase
IIAEJBAH_00115 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IIAEJBAH_00116 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
IIAEJBAH_00117 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IIAEJBAH_00118 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
IIAEJBAH_00119 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IIAEJBAH_00120 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IIAEJBAH_00121 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IIAEJBAH_00122 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IIAEJBAH_00123 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IIAEJBAH_00124 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IIAEJBAH_00125 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
IIAEJBAH_00126 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IIAEJBAH_00127 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IIAEJBAH_00128 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IIAEJBAH_00129 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IIAEJBAH_00130 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIAEJBAH_00131 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IIAEJBAH_00132 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IIAEJBAH_00133 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IIAEJBAH_00134 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IIAEJBAH_00135 2.5e-23 rpmD J ribosomal protein l30
IIAEJBAH_00136 4.4e-58 rplO J binds to the 23S rRNA
IIAEJBAH_00137 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IIAEJBAH_00138 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IIAEJBAH_00139 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IIAEJBAH_00140 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IIAEJBAH_00141 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IIAEJBAH_00142 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IIAEJBAH_00143 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIAEJBAH_00144 3.3e-62 rplQ J ribosomal protein l17
IIAEJBAH_00145 1.8e-111 L PFAM Integrase, catalytic core
IIAEJBAH_00146 3.3e-09 L PFAM Integrase, catalytic core
IIAEJBAH_00147 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
IIAEJBAH_00148 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
IIAEJBAH_00149 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
IIAEJBAH_00151 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
IIAEJBAH_00152 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
IIAEJBAH_00154 5.7e-217 S MvaI/BcnI restriction endonuclease family
IIAEJBAH_00156 7.7e-13
IIAEJBAH_00157 5e-31 S Hypothetical protein (DUF2513)
IIAEJBAH_00158 6.5e-31
IIAEJBAH_00159 1e-39
IIAEJBAH_00164 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
IIAEJBAH_00165 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIAEJBAH_00166 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
IIAEJBAH_00167 3.3e-46 K Putative DNA-binding domain
IIAEJBAH_00168 2e-94 L PFAM Integrase, catalytic core
IIAEJBAH_00169 2e-35 L PFAM Integrase, catalytic core
IIAEJBAH_00172 3.3e-95 ywlG S Belongs to the UPF0340 family
IIAEJBAH_00173 1.2e-85 treR K trehalose operon
IIAEJBAH_00174 5.8e-21 treR K DNA-binding transcription factor activity
IIAEJBAH_00175 1.4e-54 treB 2.7.1.201 G PTS System
IIAEJBAH_00176 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IIAEJBAH_00177 1.5e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IIAEJBAH_00178 0.0 pepO 3.4.24.71 O Peptidase family M13
IIAEJBAH_00179 2.1e-52 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
IIAEJBAH_00180 1.2e-133 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IIAEJBAH_00181 7.3e-74 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IIAEJBAH_00182 4.1e-22 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IIAEJBAH_00183 6.1e-64 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IIAEJBAH_00184 1.2e-277 thrC 4.2.3.1 E Threonine synthase
IIAEJBAH_00185 3.2e-226 norN V Mate efflux family protein
IIAEJBAH_00186 1.8e-57 asp S cog cog1302
IIAEJBAH_00187 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
IIAEJBAH_00188 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IIAEJBAH_00189 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
IIAEJBAH_00190 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
IIAEJBAH_00191 1.5e-194 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IIAEJBAH_00192 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IIAEJBAH_00193 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IIAEJBAH_00194 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIAEJBAH_00195 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIAEJBAH_00196 2.9e-68 S cog cog4699
IIAEJBAH_00197 6e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IIAEJBAH_00198 9.1e-156 cglB U protein transport across the cell outer membrane
IIAEJBAH_00199 8.5e-43 comGC U Required for transformation and DNA binding
IIAEJBAH_00200 1.8e-57 cglD NU Competence protein
IIAEJBAH_00201 1.4e-15 NU Type II secretory pathway pseudopilin
IIAEJBAH_00202 1.5e-71 comGF U Competence protein ComGF
IIAEJBAH_00203 2e-12 comGF U Putative Competence protein ComGF
IIAEJBAH_00204 1.1e-175 ytxK 2.1.1.72 L DNA methylase
IIAEJBAH_00205 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIAEJBAH_00206 2.6e-26 lanR K sequence-specific DNA binding
IIAEJBAH_00207 1.1e-66 V CAAX protease self-immunity
IIAEJBAH_00209 8.7e-111 S CAAX amino terminal protease family protein
IIAEJBAH_00210 4.6e-42 3.6.1.55 F NUDIX domain
IIAEJBAH_00211 4.6e-152 mutR K Transcriptional activator, Rgg GadR MutR family
IIAEJBAH_00212 1.6e-140 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
IIAEJBAH_00213 7.2e-286 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
IIAEJBAH_00214 6.6e-213 EGP Major facilitator Superfamily
IIAEJBAH_00218 8.7e-159 XK27_09825 V abc transporter atp-binding protein
IIAEJBAH_00219 1.4e-133 yvfS V ABC-2 type transporter
IIAEJBAH_00220 1.5e-192 desK 2.7.13.3 T Histidine kinase
IIAEJBAH_00221 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIAEJBAH_00222 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
IIAEJBAH_00223 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IIAEJBAH_00224 1.2e-48 S Protein of unknown function (DUF917)
IIAEJBAH_00225 1.4e-133 S Protein of unknown function (DUF917)
IIAEJBAH_00226 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
IIAEJBAH_00227 3e-111 proWZ P ABC transporter (Permease
IIAEJBAH_00228 7.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
IIAEJBAH_00229 1.5e-138 proV E abc transporter atp-binding protein
IIAEJBAH_00230 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
IIAEJBAH_00231 1.2e-62 bioY S biotin transmembrane transporter activity
IIAEJBAH_00232 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
IIAEJBAH_00233 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IIAEJBAH_00234 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIAEJBAH_00235 6.3e-23
IIAEJBAH_00236 3e-13
IIAEJBAH_00237 2.4e-92 pat 2.3.1.183 M acetyltransferase
IIAEJBAH_00238 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IIAEJBAH_00239 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IIAEJBAH_00240 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IIAEJBAH_00241 0.0 smc D Required for chromosome condensation and partitioning
IIAEJBAH_00242 1.2e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IIAEJBAH_00243 4.6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIAEJBAH_00244 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIAEJBAH_00247 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
IIAEJBAH_00248 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIAEJBAH_00250 2e-86 S ECF-type riboflavin transporter, S component
IIAEJBAH_00251 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IIAEJBAH_00252 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IIAEJBAH_00253 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
IIAEJBAH_00254 1.9e-294 yfmM S abc transporter atp-binding protein
IIAEJBAH_00255 3.4e-258 noxE P NADH oxidase
IIAEJBAH_00256 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IIAEJBAH_00257 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIAEJBAH_00258 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
IIAEJBAH_00259 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
IIAEJBAH_00260 5.3e-165 ypuA S secreted protein
IIAEJBAH_00261 8.8e-60 L Transposase (IS116 IS110 IS902 family)
IIAEJBAH_00262 4.2e-71 L Transposase (IS116 IS110 IS902 family)
IIAEJBAH_00264 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIAEJBAH_00265 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIAEJBAH_00266 2.2e-34 nrdH O Glutaredoxin
IIAEJBAH_00267 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IIAEJBAH_00268 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
IIAEJBAH_00269 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
IIAEJBAH_00270 7.9e-39 ptsH G phosphocarrier protein Hpr
IIAEJBAH_00271 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIAEJBAH_00272 4.1e-181 L Transposase
IIAEJBAH_00273 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
IIAEJBAH_00274 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IIAEJBAH_00275 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
IIAEJBAH_00276 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
IIAEJBAH_00277 0.0 uup S abc transporter atp-binding protein
IIAEJBAH_00279 6.3e-13 MA20_06245 S yiaA/B two helix domain
IIAEJBAH_00280 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
IIAEJBAH_00281 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIAEJBAH_00282 8.7e-150 cobQ S glutamine amidotransferase
IIAEJBAH_00283 1.1e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
IIAEJBAH_00284 1.2e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIAEJBAH_00285 2.3e-168 ybbR S Protein conserved in bacteria
IIAEJBAH_00286 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IIAEJBAH_00287 1.3e-70 gtrA S GtrA-like protein
IIAEJBAH_00288 7.9e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
IIAEJBAH_00289 8.1e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IIAEJBAH_00290 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
IIAEJBAH_00291 2.1e-207 yurR 1.4.5.1 E oxidoreductase
IIAEJBAH_00292 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IIAEJBAH_00293 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IIAEJBAH_00294 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IIAEJBAH_00297 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
IIAEJBAH_00298 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
IIAEJBAH_00299 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IIAEJBAH_00300 1.1e-121 ylfI S tigr01906
IIAEJBAH_00301 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
IIAEJBAH_00302 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IIAEJBAH_00303 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IIAEJBAH_00304 1.3e-22 XK27_08085
IIAEJBAH_00305 5.2e-36 L transposase activity
IIAEJBAH_00306 8.2e-26 L Integrase core domain protein
IIAEJBAH_00308 1.5e-29 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IIAEJBAH_00309 1.6e-154 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IIAEJBAH_00310 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IIAEJBAH_00311 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IIAEJBAH_00312 2.6e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IIAEJBAH_00313 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IIAEJBAH_00314 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IIAEJBAH_00315 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IIAEJBAH_00316 8.3e-21 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IIAEJBAH_00317 1e-108 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IIAEJBAH_00318 1.2e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IIAEJBAH_00319 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
IIAEJBAH_00320 5.6e-240 rodA D Belongs to the SEDS family
IIAEJBAH_00321 7.8e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IIAEJBAH_00322 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IIAEJBAH_00323 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IIAEJBAH_00324 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIAEJBAH_00325 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
IIAEJBAH_00326 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IIAEJBAH_00327 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IIAEJBAH_00328 2.9e-125 dnaD
IIAEJBAH_00329 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IIAEJBAH_00332 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIAEJBAH_00333 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
IIAEJBAH_00334 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IIAEJBAH_00335 4.7e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IIAEJBAH_00336 3.7e-73 argR K Regulates arginine biosynthesis genes
IIAEJBAH_00337 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
IIAEJBAH_00338 1.1e-147 DegV S DegV family
IIAEJBAH_00339 3.9e-143 ypmR E lipolytic protein G-D-S-L family
IIAEJBAH_00340 1.7e-83 ypmS S Protein conserved in bacteria
IIAEJBAH_00341 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IIAEJBAH_00343 1.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
IIAEJBAH_00344 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIAEJBAH_00345 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IIAEJBAH_00346 7.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IIAEJBAH_00347 2.5e-43 ysdA L Membrane
IIAEJBAH_00348 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IIAEJBAH_00349 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IIAEJBAH_00350 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
IIAEJBAH_00351 0.0 dnaE 2.7.7.7 L DNA polymerase
IIAEJBAH_00352 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IIAEJBAH_00353 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IIAEJBAH_00356 6.1e-28 Q the current gene model (or a revised gene model) may contain a frame shift
IIAEJBAH_00357 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
IIAEJBAH_00358 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
IIAEJBAH_00359 2.2e-146 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
IIAEJBAH_00360 4.4e-135 XK27_08845 S abc transporter atp-binding protein
IIAEJBAH_00361 3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIAEJBAH_00362 1.6e-151 estA CE1 S Putative esterase
IIAEJBAH_00363 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
IIAEJBAH_00364 3.3e-14 XK27_08880
IIAEJBAH_00365 2.3e-75 fld C Flavodoxin
IIAEJBAH_00366 1.3e-282 clcA P Chloride transporter, ClC family
IIAEJBAH_00367 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
IIAEJBAH_00368 3.5e-206 XK27_05110 P Chloride transporter ClC family
IIAEJBAH_00369 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IIAEJBAH_00371 5.8e-80
IIAEJBAH_00372 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
IIAEJBAH_00373 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IIAEJBAH_00374 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
IIAEJBAH_00375 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIAEJBAH_00376 1.6e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IIAEJBAH_00377 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IIAEJBAH_00378 5.9e-26 G Domain of unknown function (DUF4832)
IIAEJBAH_00379 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IIAEJBAH_00381 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIAEJBAH_00382 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
IIAEJBAH_00383 2.4e-124 endA F DNA RNA non-specific endonuclease
IIAEJBAH_00384 4.2e-110 tcyB_2 P ABC transporter (permease)
IIAEJBAH_00385 8e-115 gltJ P ABC transporter (Permease
IIAEJBAH_00386 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IIAEJBAH_00387 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
IIAEJBAH_00388 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAEJBAH_00389 1.5e-247 vicK 2.7.13.3 T Histidine kinase
IIAEJBAH_00390 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
IIAEJBAH_00391 5.3e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
IIAEJBAH_00392 4.6e-146 yidA S hydrolases of the HAD superfamily
IIAEJBAH_00393 8.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
IIAEJBAH_00394 2.6e-67 ywiB S Domain of unknown function (DUF1934)
IIAEJBAH_00395 0.0 pacL 3.6.3.8 P cation transport ATPase
IIAEJBAH_00396 1.7e-134 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IIAEJBAH_00397 9.2e-183 yjjH S Calcineurin-like phosphoesterase
IIAEJBAH_00398 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IIAEJBAH_00399 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IIAEJBAH_00400 2.5e-124 ftsE D cell division ATP-binding protein FtsE
IIAEJBAH_00401 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IIAEJBAH_00402 1.7e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
IIAEJBAH_00403 1.3e-178 yubA S permease
IIAEJBAH_00404 4.9e-224 G COG0457 FOG TPR repeat
IIAEJBAH_00405 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IIAEJBAH_00406 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IIAEJBAH_00407 2.9e-90 ebsA S Family of unknown function (DUF5322)
IIAEJBAH_00408 3.9e-15 M LysM domain
IIAEJBAH_00409 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IIAEJBAH_00410 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IIAEJBAH_00411 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IIAEJBAH_00412 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IIAEJBAH_00413 1.6e-24 L Transposase
IIAEJBAH_00414 1.7e-47 XK27_03610 K Gnat family
IIAEJBAH_00415 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IIAEJBAH_00416 2.4e-275 pepV 3.5.1.18 E Dipeptidase
IIAEJBAH_00417 1.5e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
IIAEJBAH_00419 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IIAEJBAH_00420 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IIAEJBAH_00421 9.6e-47 S Protein of unknown function (DUF1697)
IIAEJBAH_00422 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IIAEJBAH_00423 6.1e-36 clcA_2 P chloride channel
IIAEJBAH_00424 2.2e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
IIAEJBAH_00425 4.1e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
IIAEJBAH_00426 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
IIAEJBAH_00427 4.2e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
IIAEJBAH_00428 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
IIAEJBAH_00429 1.1e-103 cps4C M biosynthesis protein
IIAEJBAH_00430 1.4e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
IIAEJBAH_00431 1.7e-249 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IIAEJBAH_00432 9.7e-23 rgpAc GT4 M group 1 family protein
IIAEJBAH_00433 2.2e-22 L Transposase
IIAEJBAH_00434 8.8e-139 L Integrase core domain
IIAEJBAH_00435 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
IIAEJBAH_00436 1.3e-199 L Transposase
IIAEJBAH_00437 1.3e-23 L Transposase
IIAEJBAH_00438 1.1e-235 cps1C S Polysaccharide biosynthesis protein
IIAEJBAH_00439 2e-58 L COG2801 Transposase and inactivated derivatives
IIAEJBAH_00440 3.3e-37 L transposase activity
IIAEJBAH_00441 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
IIAEJBAH_00442 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
IIAEJBAH_00443 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
IIAEJBAH_00444 6.5e-72 M Glycosyltransferase sugar-binding region containing DXD motif
IIAEJBAH_00445 7.8e-16
IIAEJBAH_00446 6.4e-33 cpsJ S Glycosyltransferase like family 2
IIAEJBAH_00447 6.2e-112 L the current gene model (or a revised gene model) may contain a frame shift
IIAEJBAH_00448 3.1e-37 L Transposase
IIAEJBAH_00449 2.2e-94 V VanZ like family
IIAEJBAH_00450 5.4e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IIAEJBAH_00451 5.6e-65 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
IIAEJBAH_00452 1.1e-95 pgm G Belongs to the phosphoglycerate mutase family
IIAEJBAH_00453 7.2e-104 G Belongs to the phosphoglycerate mutase family
IIAEJBAH_00454 2.5e-99 G Belongs to the phosphoglycerate mutase family
IIAEJBAH_00455 1.1e-198 S hmm pf01594
IIAEJBAH_00456 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIAEJBAH_00457 2.6e-97 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIAEJBAH_00458 3.2e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIAEJBAH_00459 4.9e-39 S granule-associated protein
IIAEJBAH_00460 8.5e-290 S unusual protein kinase
IIAEJBAH_00461 5.5e-34 estA E Lysophospholipase L1 and related esterases
IIAEJBAH_00462 1.9e-59 estA E GDSL-like protein
IIAEJBAH_00463 1.1e-158 rssA S Phospholipase, patatin family
IIAEJBAH_00464 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
IIAEJBAH_00465 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
IIAEJBAH_00466 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
IIAEJBAH_00467 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
IIAEJBAH_00468 5.4e-19 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
IIAEJBAH_00469 4e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIAEJBAH_00470 7.2e-126 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IIAEJBAH_00471 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IIAEJBAH_00472 5.7e-66 S the current gene model (or a revised gene model) may contain a frame shift
IIAEJBAH_00473 5e-38 P membrane protein (DUF2207)
IIAEJBAH_00474 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IIAEJBAH_00475 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IIAEJBAH_00476 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIAEJBAH_00477 0.0 lpdA 1.8.1.4 C Dehydrogenase
IIAEJBAH_00478 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IIAEJBAH_00479 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IIAEJBAH_00480 8.5e-266 3.5.1.28 NU amidase activity
IIAEJBAH_00481 1.9e-37 3.5.1.28 NU amidase activity
IIAEJBAH_00482 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAEJBAH_00483 6.1e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAEJBAH_00484 3.8e-54 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAEJBAH_00485 2e-139 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAEJBAH_00486 4e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIAEJBAH_00487 1.9e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIAEJBAH_00488 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
IIAEJBAH_00489 6.5e-177 fatB P ABC-type enterochelin transport system, periplasmic component
IIAEJBAH_00490 4.6e-152 ycdO P periplasmic lipoprotein involved in iron transport
IIAEJBAH_00491 1.5e-233 ycdB P peroxidase
IIAEJBAH_00492 3.9e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
IIAEJBAH_00493 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IIAEJBAH_00494 4.6e-25 tatA U protein secretion
IIAEJBAH_00495 2.3e-23 L Transposase
IIAEJBAH_00496 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
IIAEJBAH_00497 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IIAEJBAH_00498 3.7e-09
IIAEJBAH_00500 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
IIAEJBAH_00501 1.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IIAEJBAH_00502 0.0 pepN 3.4.11.2 E aminopeptidase
IIAEJBAH_00503 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
IIAEJBAH_00504 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIAEJBAH_00505 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIAEJBAH_00506 5.9e-155 pstA P phosphate transport system permease
IIAEJBAH_00507 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
IIAEJBAH_00508 4.3e-158 pstS P phosphate
IIAEJBAH_00509 1.5e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IIAEJBAH_00510 1.1e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IIAEJBAH_00511 1.9e-43 yktA S Belongs to the UPF0223 family
IIAEJBAH_00512 4.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IIAEJBAH_00513 2.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IIAEJBAH_00514 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IIAEJBAH_00515 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
IIAEJBAH_00516 3.6e-136 XK27_04775 S hemerythrin HHE cation binding domain
IIAEJBAH_00517 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
IIAEJBAH_00518 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IIAEJBAH_00519 9.3e-62 S haloacid dehalogenase-like hydrolase
IIAEJBAH_00520 1.8e-59 Q phosphatase activity
IIAEJBAH_00521 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
IIAEJBAH_00522 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IIAEJBAH_00523 1.8e-240 agcS E (Alanine) symporter
IIAEJBAH_00524 1.3e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IIAEJBAH_00525 1.4e-104 yfiF3 K sequence-specific DNA binding
IIAEJBAH_00526 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
IIAEJBAH_00527 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
IIAEJBAH_00529 1.8e-67 yecS P ABC transporter (Permease
IIAEJBAH_00530 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
IIAEJBAH_00531 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
IIAEJBAH_00532 7.9e-266 dtpT E transporter
IIAEJBAH_00534 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
IIAEJBAH_00535 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IIAEJBAH_00536 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IIAEJBAH_00537 3.4e-61 csm6 S Psort location Cytoplasmic, score
IIAEJBAH_00538 1.9e-203 csm5 L CRISPR-associated RAMP protein, Csm5 family
IIAEJBAH_00539 1.4e-164 csm4 L CRISPR-associated RAMP protein, Csm4 family
IIAEJBAH_00540 1.1e-116 csm3 L RAMP superfamily
IIAEJBAH_00541 5.6e-62 csm2 L Pfam:DUF310
IIAEJBAH_00542 0.0 csm1 S CRISPR-associated protein Csm1 family
IIAEJBAH_00543 1.3e-131 cas6 S CRISPR-associated endoribonuclease Cas6
IIAEJBAH_00544 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIAEJBAH_00545 1.8e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIAEJBAH_00546 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IIAEJBAH_00547 6.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IIAEJBAH_00548 3.2e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
IIAEJBAH_00549 2.1e-98 S TraX protein
IIAEJBAH_00551 1.7e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IIAEJBAH_00552 6.5e-266 S Psort location CytoplasmicMembrane, score
IIAEJBAH_00553 5.1e-26 dinF V drug transmembrane transporter activity
IIAEJBAH_00554 6.3e-12 dinF V Mate efflux family protein
IIAEJBAH_00555 9.6e-72 dinF V Mate efflux family protein
IIAEJBAH_00556 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
IIAEJBAH_00557 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
IIAEJBAH_00558 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
IIAEJBAH_00559 2.6e-143 2.4.2.3 F Phosphorylase superfamily
IIAEJBAH_00562 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
IIAEJBAH_00563 1.8e-16 S Alpha/beta hydrolase of unknown function (DUF915)
IIAEJBAH_00564 6e-08 S Hydrolases of the alpha beta superfamily
IIAEJBAH_00565 2.7e-106 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
IIAEJBAH_00566 8.1e-52 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
IIAEJBAH_00567 1e-209 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IIAEJBAH_00568 1.2e-158 czcD P cation diffusion facilitator family transporter
IIAEJBAH_00569 1.2e-97 K Transcriptional regulator, TetR family
IIAEJBAH_00571 6.1e-13 L Transposase
IIAEJBAH_00572 1e-193 L Transposase
IIAEJBAH_00573 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IIAEJBAH_00574 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IIAEJBAH_00575 6.6e-61 EGP Major facilitator Superfamily
IIAEJBAH_00576 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
IIAEJBAH_00577 1.3e-212 pqqE C radical SAM domain protein
IIAEJBAH_00580 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IIAEJBAH_00581 4.1e-53 K peptidyl-tyrosine sulfation
IIAEJBAH_00585 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IIAEJBAH_00586 3.9e-19 IQ Acetoin reductase
IIAEJBAH_00587 6.8e-51 IQ Acetoin reductase
IIAEJBAH_00588 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIAEJBAH_00589 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IIAEJBAH_00590 1.9e-152 XK27_05470 E Methionine synthase
IIAEJBAH_00591 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IIAEJBAH_00592 6.9e-251 T PhoQ Sensor
IIAEJBAH_00593 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAEJBAH_00594 5.1e-153 S TraX protein
IIAEJBAH_00595 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIAEJBAH_00596 2.4e-158 dprA LU DNA protecting protein DprA
IIAEJBAH_00597 1.1e-167 GK ROK family
IIAEJBAH_00598 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIAEJBAH_00599 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IIAEJBAH_00600 6.9e-127 K DNA-binding helix-turn-helix protein
IIAEJBAH_00601 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
IIAEJBAH_00602 2.4e-87 niaX
IIAEJBAH_00603 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IIAEJBAH_00604 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IIAEJBAH_00605 2e-126 gntR1 K transcriptional
IIAEJBAH_00606 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IIAEJBAH_00607 0.0 res_1 3.1.21.5 S Type III restriction
IIAEJBAH_00608 1.1e-20
IIAEJBAH_00610 7.4e-110 adhP 1.1.1.1 C alcohol dehydrogenase
IIAEJBAH_00611 2.3e-62 adhP 1.1.1.1 C alcohol dehydrogenase
IIAEJBAH_00612 3.1e-142 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIAEJBAH_00613 1.4e-158 aatB ET ABC transporter substrate-binding protein
IIAEJBAH_00614 3.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
IIAEJBAH_00615 5.3e-105 artQ P ABC transporter (Permease
IIAEJBAH_00616 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
IIAEJBAH_00617 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IIAEJBAH_00618 4.5e-166 cpsY K Transcriptional regulator
IIAEJBAH_00619 6.6e-71 L transposition
IIAEJBAH_00620 1.9e-119 mur1 NU muramidase
IIAEJBAH_00621 1.5e-170 yeiH S Membrane
IIAEJBAH_00622 1.7e-08
IIAEJBAH_00623 2.1e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
IIAEJBAH_00624 3.7e-88 XK27_10720 D peptidase activity
IIAEJBAH_00625 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
IIAEJBAH_00626 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
IIAEJBAH_00627 2.9e-154 glcU U Glucose uptake
IIAEJBAH_00628 5.2e-113 hsdM 2.1.1.72 V type I restriction-modification system
IIAEJBAH_00629 5.2e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
IIAEJBAH_00630 9.4e-43 K Cold-Shock Protein
IIAEJBAH_00631 5.4e-32 cspD K Cold shock protein domain
IIAEJBAH_00632 5.8e-41 pepD E dipeptidase activity
IIAEJBAH_00633 8e-90 pepD E Dipeptidase
IIAEJBAH_00634 8.7e-162 whiA K May be required for sporulation
IIAEJBAH_00635 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IIAEJBAH_00636 1.2e-163 rapZ S Displays ATPase and GTPase activities
IIAEJBAH_00637 5.3e-136 yejC S cyclic nucleotide-binding protein
IIAEJBAH_00638 4.2e-18 D nuclear chromosome segregation
IIAEJBAH_00639 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IIAEJBAH_00640 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IIAEJBAH_00641 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
IIAEJBAH_00642 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IIAEJBAH_00643 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
IIAEJBAH_00644 3e-13
IIAEJBAH_00645 2.4e-30
IIAEJBAH_00646 1.5e-07
IIAEJBAH_00647 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IIAEJBAH_00648 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IIAEJBAH_00649 3.1e-81 ypmB S Protein conserved in bacteria
IIAEJBAH_00650 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IIAEJBAH_00651 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IIAEJBAH_00652 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
IIAEJBAH_00653 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
IIAEJBAH_00654 2.7e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IIAEJBAH_00655 1.5e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IIAEJBAH_00656 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IIAEJBAH_00657 1.5e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IIAEJBAH_00658 5.5e-29 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IIAEJBAH_00659 7.5e-101 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IIAEJBAH_00660 1.3e-24 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
IIAEJBAH_00661 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
IIAEJBAH_00662 2.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
IIAEJBAH_00663 2.1e-30 rpsT J rRNA binding
IIAEJBAH_00664 9.2e-110 T PhoQ Sensor
IIAEJBAH_00665 4.3e-41 T PhoQ Sensor
IIAEJBAH_00666 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAEJBAH_00667 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IIAEJBAH_00668 6.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
IIAEJBAH_00669 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IIAEJBAH_00670 1.6e-92 panT S ECF transporter, substrate-specific component
IIAEJBAH_00671 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IIAEJBAH_00672 7.3e-166 metF 1.5.1.20 C reductase
IIAEJBAH_00673 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IIAEJBAH_00675 7.1e-217 sip L Belongs to the 'phage' integrase family
IIAEJBAH_00676 6e-39 K Helix-turn-helix
IIAEJBAH_00677 5.5e-17 K TRANSCRIPTIONal
IIAEJBAH_00682 6.9e-22
IIAEJBAH_00683 3e-164 KL Phage plasmid primase P4 family
IIAEJBAH_00684 2e-296 S DNA primase
IIAEJBAH_00686 2.3e-12
IIAEJBAH_00688 2e-103
IIAEJBAH_00689 1.4e-66 S tRNA_anti-like
IIAEJBAH_00690 4e-22 L Belongs to the 'phage' integrase family
IIAEJBAH_00691 3e-44 ymbI L transposase activity
IIAEJBAH_00692 2.6e-72 hpaIIR 3.1.21.4 L HpaII restriction endonuclease
IIAEJBAH_00693 1.7e-146 2.1.1.37 H cytosine-specific methyltransferase
IIAEJBAH_00694 5.1e-106 V Abi-like protein
IIAEJBAH_00695 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
IIAEJBAH_00696 0.0 3.6.3.8 P cation transport ATPase
IIAEJBAH_00697 4.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIAEJBAH_00698 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IIAEJBAH_00699 4.1e-09 S Domain of unknown function (DUF4651)
IIAEJBAH_00700 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IIAEJBAH_00701 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIAEJBAH_00702 2.6e-68 yeeE S Sulphur transport
IIAEJBAH_00703 2e-109 yeeE S Sulphur transport
IIAEJBAH_00704 1.9e-36 yeeD O sulfur carrier activity
IIAEJBAH_00705 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIAEJBAH_00706 1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IIAEJBAH_00709 4.1e-158 rrmA 2.1.1.187 Q methyltransferase
IIAEJBAH_00710 1.5e-64 S phosphatase activity
IIAEJBAH_00711 1.9e-46 S glycolate biosynthetic process
IIAEJBAH_00712 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IIAEJBAH_00713 1.3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IIAEJBAH_00714 8.5e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IIAEJBAH_00715 7.5e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IIAEJBAH_00716 1.6e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IIAEJBAH_00717 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IIAEJBAH_00718 1.3e-83 XK27_08585 S Psort location CytoplasmicMembrane, score
IIAEJBAH_00719 2.5e-116 fnt P Formate nitrite transporter
IIAEJBAH_00720 1.5e-220 XK27_09615 C reductase
IIAEJBAH_00721 6.2e-76 XK27_09620 S reductase
IIAEJBAH_00722 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
IIAEJBAH_00723 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IIAEJBAH_00724 1.8e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IIAEJBAH_00725 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
IIAEJBAH_00726 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
IIAEJBAH_00727 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
IIAEJBAH_00728 5.2e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IIAEJBAH_00729 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIAEJBAH_00730 4.6e-238 dltB M Membrane protein involved in D-alanine export
IIAEJBAH_00731 9.3e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIAEJBAH_00732 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
IIAEJBAH_00733 0.0 XK27_10035 V abc transporter atp-binding protein
IIAEJBAH_00734 0.0 yfiB1 V abc transporter atp-binding protein
IIAEJBAH_00735 2.4e-107 pvaA M lytic transglycosylase activity
IIAEJBAH_00736 6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
IIAEJBAH_00737 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IIAEJBAH_00738 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IIAEJBAH_00739 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IIAEJBAH_00740 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IIAEJBAH_00741 4.5e-111 tdk 2.7.1.21 F thymidine kinase
IIAEJBAH_00742 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IIAEJBAH_00743 8.9e-155 gst O Glutathione S-transferase
IIAEJBAH_00744 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
IIAEJBAH_00745 1.9e-175 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IIAEJBAH_00746 2e-45 rpmE2 J 50S ribosomal protein L31
IIAEJBAH_00747 8.8e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
IIAEJBAH_00749 3.2e-45 L Transposase
IIAEJBAH_00750 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IIAEJBAH_00751 3.3e-134 divIVA D Cell division protein DivIVA
IIAEJBAH_00752 4.7e-143 ylmH T S4 RNA-binding domain
IIAEJBAH_00753 8.8e-35 yggT D integral membrane protein
IIAEJBAH_00754 2e-95 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IIAEJBAH_00755 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IIAEJBAH_00756 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IIAEJBAH_00757 1.1e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IIAEJBAH_00758 6.9e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IIAEJBAH_00759 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IIAEJBAH_00760 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IIAEJBAH_00762 0.0 typA T GTP-binding protein TypA
IIAEJBAH_00763 1.6e-177 glk 2.7.1.2 G Glucokinase
IIAEJBAH_00764 8.4e-28 yqgQ S protein conserved in bacteria
IIAEJBAH_00765 1.1e-80 perR P Belongs to the Fur family
IIAEJBAH_00766 1.6e-91 dps P Belongs to the Dps family
IIAEJBAH_00767 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IIAEJBAH_00768 1.4e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
IIAEJBAH_00769 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
IIAEJBAH_00770 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
IIAEJBAH_00771 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IIAEJBAH_00772 6.2e-56 S Domain of unknown function (DUF4430)
IIAEJBAH_00773 5.1e-73 S Psort location CytoplasmicMembrane, score
IIAEJBAH_00774 1.8e-135 htpX O Belongs to the peptidase M48B family
IIAEJBAH_00775 1.5e-92 lemA S LemA family
IIAEJBAH_00776 8.8e-157 spd F DNA RNA non-specific endonuclease
IIAEJBAH_00777 3e-38
IIAEJBAH_00778 2.5e-44
IIAEJBAH_00780 9.3e-68 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
IIAEJBAH_00781 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
IIAEJBAH_00782 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
IIAEJBAH_00783 1.4e-44 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIAEJBAH_00784 8.3e-76 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIAEJBAH_00785 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
IIAEJBAH_00786 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
IIAEJBAH_00787 1.4e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIAEJBAH_00788 2.1e-27 P Hemerythrin HHE cation binding domain protein
IIAEJBAH_00789 2.2e-144 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
IIAEJBAH_00790 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IIAEJBAH_00791 5.1e-116 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
IIAEJBAH_00792 9.8e-174 S hydrolase
IIAEJBAH_00793 5.9e-16
IIAEJBAH_00794 1.5e-154 M LysM domain
IIAEJBAH_00795 1.9e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IIAEJBAH_00796 1.2e-33 S SIR2-like domain
IIAEJBAH_00797 5.2e-29 S SIR2-like domain
IIAEJBAH_00798 1.2e-224 mutH L DNA mismatch repair enzyme MutH
IIAEJBAH_00799 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
IIAEJBAH_00800 4.8e-11
IIAEJBAH_00801 7.3e-234 mntH P H( )-stimulated, divalent metal cation uptake system
IIAEJBAH_00802 1.1e-33 XK27_12190 S protein conserved in bacteria
IIAEJBAH_00804 8.4e-88 bioY S biotin synthase
IIAEJBAH_00805 8.1e-46 S CHY zinc finger
IIAEJBAH_00806 3.4e-252 yegQ O Peptidase U32
IIAEJBAH_00807 2e-177 yegQ O Peptidase U32
IIAEJBAH_00809 5.5e-69 ytxH S General stress protein
IIAEJBAH_00811 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IIAEJBAH_00812 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IIAEJBAH_00813 9.9e-42 pspC KT PspC domain
IIAEJBAH_00814 0.0 yhgF K Transcriptional accessory protein
IIAEJBAH_00816 1.2e-155 XK27_03015 S permease
IIAEJBAH_00817 2.3e-145 ycgQ S TIGR03943 family
IIAEJBAH_00818 9e-195 S CRISPR-associated protein Csn2 subfamily St
IIAEJBAH_00819 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIAEJBAH_00820 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIAEJBAH_00821 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IIAEJBAH_00822 1.1e-94
IIAEJBAH_00823 4.8e-33 estA E GDSL-like Lipase/Acylhydrolase
IIAEJBAH_00824 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
IIAEJBAH_00825 1e-31 K Cro/C1-type HTH DNA-binding domain
IIAEJBAH_00826 1.2e-45
IIAEJBAH_00827 8.9e-20
IIAEJBAH_00828 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIAEJBAH_00829 4.5e-97 mip S hydroperoxide reductase activity
IIAEJBAH_00830 7e-203 I acyl-CoA dehydrogenase
IIAEJBAH_00831 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
IIAEJBAH_00832 6.4e-252 msrR K Transcriptional regulator
IIAEJBAH_00833 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
IIAEJBAH_00834 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IIAEJBAH_00835 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IIAEJBAH_00836 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IIAEJBAH_00837 3.2e-53 yheA S Belongs to the UPF0342 family
IIAEJBAH_00838 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IIAEJBAH_00839 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IIAEJBAH_00840 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IIAEJBAH_00841 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IIAEJBAH_00842 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IIAEJBAH_00843 2e-219 ywbD 2.1.1.191 J Methyltransferase
IIAEJBAH_00844 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IIAEJBAH_00845 2e-25 WQ51_00785
IIAEJBAH_00846 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IIAEJBAH_00847 1e-78 yueI S Protein of unknown function (DUF1694)
IIAEJBAH_00848 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IIAEJBAH_00849 6.6e-101 yyaQ V Protein conserved in bacteria
IIAEJBAH_00850 2.8e-28 yyaQ S YjbR
IIAEJBAH_00851 4.4e-183 ccpA K Catabolite control protein A
IIAEJBAH_00852 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
IIAEJBAH_00853 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
IIAEJBAH_00854 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIAEJBAH_00855 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IIAEJBAH_00856 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IIAEJBAH_00857 2e-33 secG U Preprotein translocase subunit SecG
IIAEJBAH_00858 2.5e-220 mdtG EGP Major facilitator Superfamily
IIAEJBAH_00859 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IIAEJBAH_00860 7.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IIAEJBAH_00861 8.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IIAEJBAH_00862 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IIAEJBAH_00863 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IIAEJBAH_00864 6.8e-53 licT K transcriptional antiterminator
IIAEJBAH_00865 5.8e-64 licT K transcriptional antiterminator
IIAEJBAH_00866 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IIAEJBAH_00867 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
IIAEJBAH_00868 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IIAEJBAH_00869 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IIAEJBAH_00870 7.5e-23 I Alpha/beta hydrolase family
IIAEJBAH_00871 1.5e-35 yugF I carboxylic ester hydrolase activity
IIAEJBAH_00872 2.2e-45 K sequence-specific DNA binding
IIAEJBAH_00873 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IIAEJBAH_00875 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IIAEJBAH_00876 3.1e-78 feoA P FeoA domain protein
IIAEJBAH_00877 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
IIAEJBAH_00878 3.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
IIAEJBAH_00879 1.3e-34 ykuJ S protein conserved in bacteria
IIAEJBAH_00880 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IIAEJBAH_00881 0.0 clpE O Belongs to the ClpA ClpB family
IIAEJBAH_00882 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IIAEJBAH_00883 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
IIAEJBAH_00884 1.2e-65 S oxidoreductase
IIAEJBAH_00885 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
IIAEJBAH_00886 3.7e-70 M Pfam SNARE associated Golgi protein
IIAEJBAH_00887 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
IIAEJBAH_00888 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
IIAEJBAH_00891 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
IIAEJBAH_00894 4.8e-16 S Protein of unknown function (DUF2969)
IIAEJBAH_00895 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
IIAEJBAH_00896 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIAEJBAH_00897 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIAEJBAH_00898 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IIAEJBAH_00899 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
IIAEJBAH_00900 1.4e-29 S Domain of unknown function (DUF1912)
IIAEJBAH_00901 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
IIAEJBAH_00902 1.5e-250 mmuP E amino acid
IIAEJBAH_00903 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IIAEJBAH_00904 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IIAEJBAH_00905 9.7e-22
IIAEJBAH_00906 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IIAEJBAH_00907 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IIAEJBAH_00908 1.7e-218 mvaS 2.3.3.10 I synthase
IIAEJBAH_00909 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IIAEJBAH_00910 1e-25 K hmm pf08876
IIAEJBAH_00911 1.1e-116 yqfA K protein, Hemolysin III
IIAEJBAH_00912 1.6e-22 S Protein of unknown function (DUF3114)
IIAEJBAH_00913 1.1e-161 S Protein of unknown function (DUF3114)
IIAEJBAH_00914 1.6e-70 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IIAEJBAH_00915 2.3e-57 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IIAEJBAH_00916 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIAEJBAH_00917 5.5e-49 XK27_13030
IIAEJBAH_00918 1.2e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IIAEJBAH_00919 4.4e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
IIAEJBAH_00920 4.2e-68 U protein secretion
IIAEJBAH_00921 3e-29 U protein secretion
IIAEJBAH_00923 1.7e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IIAEJBAH_00924 2.5e-21
IIAEJBAH_00925 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
IIAEJBAH_00926 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IIAEJBAH_00927 2.4e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IIAEJBAH_00928 1e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
IIAEJBAH_00929 1.4e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IIAEJBAH_00930 7.9e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IIAEJBAH_00931 8.8e-104 GBS0088 J protein conserved in bacteria
IIAEJBAH_00932 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IIAEJBAH_00933 1.3e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
IIAEJBAH_00934 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
IIAEJBAH_00935 7e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IIAEJBAH_00936 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IIAEJBAH_00937 2.5e-113 S VIT family
IIAEJBAH_00938 6.5e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
IIAEJBAH_00939 1.9e-22
IIAEJBAH_00940 8e-28 XK27_00085 K Transcriptional
IIAEJBAH_00941 6.9e-197 yceA S Belongs to the UPF0176 family
IIAEJBAH_00942 5.4e-122 sagI S ABC-2 type transporter
IIAEJBAH_00943 2.8e-168 V ABC transporter
IIAEJBAH_00944 2.5e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IIAEJBAH_00945 2.5e-132 rr02 KT response regulator
IIAEJBAH_00946 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
IIAEJBAH_00947 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IIAEJBAH_00948 1.3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IIAEJBAH_00949 0.0 lmrA V abc transporter atp-binding protein
IIAEJBAH_00950 0.0 mdlB V abc transporter atp-binding protein
IIAEJBAH_00952 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IIAEJBAH_00953 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IIAEJBAH_00954 7.2e-24 ytrF V efflux transmembrane transporter activity
IIAEJBAH_00955 4.6e-43 V efflux transmembrane transporter activity
IIAEJBAH_00956 1.7e-59 V permease protein
IIAEJBAH_00957 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IIAEJBAH_00958 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IIAEJBAH_00959 5.1e-131 2.1.1.223 S Putative SAM-dependent methyltransferase
IIAEJBAH_00960 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
IIAEJBAH_00961 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
IIAEJBAH_00962 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IIAEJBAH_00963 3.7e-227 pyrP F uracil Permease
IIAEJBAH_00964 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IIAEJBAH_00965 2.9e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IIAEJBAH_00966 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IIAEJBAH_00967 1.4e-167 fhuR K transcriptional regulator (lysR family)
IIAEJBAH_00973 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIAEJBAH_00974 1.4e-75 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
IIAEJBAH_00975 9.4e-119 pts33BCA G pts system
IIAEJBAH_00976 5.8e-71 pts33BCA G pts system
IIAEJBAH_00977 4.8e-24 pts33BCA G pts system
IIAEJBAH_00978 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
IIAEJBAH_00979 1.8e-254 cycA E permease
IIAEJBAH_00980 4.5e-39 ynzC S UPF0291 protein
IIAEJBAH_00981 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IIAEJBAH_00982 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IIAEJBAH_00983 1.7e-32 S membrane
IIAEJBAH_00984 1.2e-61
IIAEJBAH_00985 4.4e-26
IIAEJBAH_00986 7.4e-55
IIAEJBAH_00987 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IIAEJBAH_00988 1.5e-114 nptA P COG1283 Na phosphate symporter
IIAEJBAH_00989 2.9e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
IIAEJBAH_00990 9.2e-105 mur1 NU mannosyl-glycoprotein
IIAEJBAH_00991 1.2e-52 glnB K Belongs to the P(II) protein family
IIAEJBAH_00992 2.9e-232 amt P Ammonium Transporter
IIAEJBAH_00993 4.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IIAEJBAH_00994 9.5e-55 yabA L Involved in initiation control of chromosome replication
IIAEJBAH_00995 1.2e-135 yaaT S stage 0 sporulation protein
IIAEJBAH_00996 6.4e-162 holB 2.7.7.7 L dna polymerase iii
IIAEJBAH_00997 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IIAEJBAH_00998 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIAEJBAH_00999 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IIAEJBAH_01000 2.8e-230 ftsW D Belongs to the SEDS family
IIAEJBAH_01001 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IIAEJBAH_01002 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IIAEJBAH_01003 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IIAEJBAH_01004 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IIAEJBAH_01005 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIAEJBAH_01006 3.3e-78 atpF C ATP synthase F(0) sector subunit b
IIAEJBAH_01007 2.4e-114 atpB C it plays a direct role in the translocation of protons across the membrane
IIAEJBAH_01008 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIAEJBAH_01009 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IIAEJBAH_01010 5.9e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IIAEJBAH_01011 8e-51 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IIAEJBAH_01012 8.9e-14 coiA 3.6.4.12 S Competence protein
IIAEJBAH_01013 2.9e-15 T peptidase
IIAEJBAH_01014 1.4e-151 rarD S Transporter
IIAEJBAH_01015 6.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IIAEJBAH_01016 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IIAEJBAH_01017 2.2e-130 yxkH G deacetylase
IIAEJBAH_01018 1.4e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IIAEJBAH_01019 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IIAEJBAH_01020 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IIAEJBAH_01021 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IIAEJBAH_01022 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
IIAEJBAH_01023 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IIAEJBAH_01024 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
IIAEJBAH_01025 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IIAEJBAH_01026 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IIAEJBAH_01027 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IIAEJBAH_01028 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
IIAEJBAH_01029 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
IIAEJBAH_01030 0.0 pepF E oligoendopeptidase F
IIAEJBAH_01031 1.4e-186 coiA 3.6.4.12 S Competence protein
IIAEJBAH_01032 1.8e-164 K transcriptional regulator (lysR family)
IIAEJBAH_01033 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IIAEJBAH_01037 8e-191 phoH T phosphate starvation-inducible protein PhoH
IIAEJBAH_01038 2.3e-61 rlpA M LysM domain protein
IIAEJBAH_01039 1.5e-123 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
IIAEJBAH_01040 7.4e-35 yozE S Belongs to the UPF0346 family
IIAEJBAH_01041 1.7e-159 cvfB S Protein conserved in bacteria
IIAEJBAH_01042 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IIAEJBAH_01043 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IIAEJBAH_01044 1.3e-120 sptS 2.7.13.3 T Histidine kinase
IIAEJBAH_01045 1.4e-45 K Acetyltransferase (GNAT) family
IIAEJBAH_01046 0.0 lmrA2 V abc transporter atp-binding protein
IIAEJBAH_01047 0.0 lmrA1 V abc transporter atp-binding protein
IIAEJBAH_01048 1.9e-77 K DNA-binding transcription factor activity
IIAEJBAH_01049 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IIAEJBAH_01050 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IIAEJBAH_01051 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
IIAEJBAH_01052 6.5e-77 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
IIAEJBAH_01053 7.2e-25 U response to pH
IIAEJBAH_01054 0.0 yfmR S abc transporter atp-binding protein
IIAEJBAH_01055 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IIAEJBAH_01056 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IIAEJBAH_01057 9.8e-91 XK27_08360 S EDD domain protein, DegV family
IIAEJBAH_01058 2.6e-64 WQ51_03320 S cog cog4835
IIAEJBAH_01059 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IIAEJBAH_01060 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IIAEJBAH_01061 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IIAEJBAH_01062 6.4e-29 2.3.1.128 K acetyltransferase
IIAEJBAH_01063 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IIAEJBAH_01064 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IIAEJBAH_01065 1.2e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIAEJBAH_01066 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IIAEJBAH_01068 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IIAEJBAH_01069 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IIAEJBAH_01070 0.0 fruA 2.7.1.202 G phosphotransferase system
IIAEJBAH_01071 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IIAEJBAH_01072 5.5e-122 fruR K transcriptional
IIAEJBAH_01073 8.9e-84 L Transposase
IIAEJBAH_01074 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
IIAEJBAH_01075 6.6e-38 L transposase activity
IIAEJBAH_01076 1.2e-61 L transposition
IIAEJBAH_01077 5e-72 L COG2801 Transposase and inactivated derivatives
IIAEJBAH_01078 1.1e-113 K sequence-specific DNA binding
IIAEJBAH_01079 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
IIAEJBAH_01080 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
IIAEJBAH_01081 7.7e-198 V (ABC) transporter
IIAEJBAH_01082 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
IIAEJBAH_01083 1.1e-176 S Protein of unknown function (DUF3114)
IIAEJBAH_01084 2.7e-82 S Protein of unknown function (DUF3114)
IIAEJBAH_01086 1.1e-65 tnp L Transposase
IIAEJBAH_01087 4.7e-27 L Transposase and inactivated derivatives, TnpA family
IIAEJBAH_01088 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
IIAEJBAH_01089 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
IIAEJBAH_01090 1.1e-65 tnp L Transposase
IIAEJBAH_01091 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IIAEJBAH_01092 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IIAEJBAH_01093 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IIAEJBAH_01094 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IIAEJBAH_01095 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIAEJBAH_01096 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIAEJBAH_01097 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIAEJBAH_01098 1.6e-126 IQ reductase
IIAEJBAH_01099 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IIAEJBAH_01100 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
IIAEJBAH_01101 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIAEJBAH_01102 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIAEJBAH_01103 4e-72 marR K Transcriptional regulator, MarR family
IIAEJBAH_01104 6.9e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
IIAEJBAH_01105 1.6e-114 S Haloacid dehalogenase-like hydrolase
IIAEJBAH_01106 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
IIAEJBAH_01107 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
IIAEJBAH_01108 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIAEJBAH_01109 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
IIAEJBAH_01110 1.3e-101 ygaC J Belongs to the UPF0374 family
IIAEJBAH_01111 6.4e-108 S Domain of unknown function (DUF1803)
IIAEJBAH_01112 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
IIAEJBAH_01119 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IIAEJBAH_01120 1.7e-122 comFC S Competence protein
IIAEJBAH_01121 5.9e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IIAEJBAH_01122 1.1e-110 yvyE 3.4.13.9 S YigZ family
IIAEJBAH_01123 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IIAEJBAH_01124 8.9e-41 acuB S IMP dehydrogenase activity
IIAEJBAH_01125 6.8e-69 acuB S IMP dehydrogenase activity
IIAEJBAH_01126 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IIAEJBAH_01127 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IIAEJBAH_01128 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
IIAEJBAH_01129 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
IIAEJBAH_01130 1.3e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IIAEJBAH_01131 7.1e-46 ylbG S UPF0298 protein
IIAEJBAH_01132 1.2e-74 ylbF S Belongs to the UPF0342 family
IIAEJBAH_01133 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IIAEJBAH_01134 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IIAEJBAH_01137 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IIAEJBAH_01138 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
IIAEJBAH_01139 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
IIAEJBAH_01140 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
IIAEJBAH_01141 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IIAEJBAH_01142 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
IIAEJBAH_01143 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
IIAEJBAH_01144 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
IIAEJBAH_01145 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
IIAEJBAH_01146 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IIAEJBAH_01147 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IIAEJBAH_01148 1.4e-41 ylxQ J ribosomal protein
IIAEJBAH_01149 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
IIAEJBAH_01150 3.1e-212 nusA K Participates in both transcription termination and antitermination
IIAEJBAH_01151 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
IIAEJBAH_01152 2.5e-220 brpA K Transcriptional
IIAEJBAH_01153 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
IIAEJBAH_01154 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
IIAEJBAH_01155 2.5e-248 pbuO S permease
IIAEJBAH_01156 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IIAEJBAH_01157 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
IIAEJBAH_01158 1.1e-181 manL 2.7.1.191 G pts system
IIAEJBAH_01159 5e-108 manM G pts system
IIAEJBAH_01160 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
IIAEJBAH_01161 4.2e-62 manO S protein conserved in bacteria
IIAEJBAH_01162 8e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IIAEJBAH_01163 2.6e-94 L Integrase core domain
IIAEJBAH_01164 1.4e-36 L Integrase core domain
IIAEJBAH_01165 0.0 M domain protein
IIAEJBAH_01166 2.1e-12 G gluconolactonase activity
IIAEJBAH_01167 1.3e-125 tnp L DDE domain
IIAEJBAH_01168 5.9e-17 lytN 3.5.1.104 M LysM domain
IIAEJBAH_01169 2.8e-160 L Transposase DDE domain
IIAEJBAH_01170 4.3e-41 L Protein of unknown function (DUF3991)
IIAEJBAH_01172 2.3e-42 L transposase activity
IIAEJBAH_01173 5e-17 L Transposase
IIAEJBAH_01174 5.9e-55 L transposition
IIAEJBAH_01175 5.4e-85 L PFAM Integrase catalytic region
IIAEJBAH_01176 9e-88 yrdC 3.5.1.19 Q isochorismatase
IIAEJBAH_01177 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IIAEJBAH_01178 4e-167 dnaI L Primosomal protein DnaI
IIAEJBAH_01179 5e-218 dnaB L Replication initiation and membrane attachment
IIAEJBAH_01180 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IIAEJBAH_01181 3.3e-275 T PhoQ Sensor
IIAEJBAH_01182 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAEJBAH_01183 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
IIAEJBAH_01184 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
IIAEJBAH_01185 1.4e-243 P COG0168 Trk-type K transport systems, membrane components
IIAEJBAH_01186 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
IIAEJBAH_01187 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
IIAEJBAH_01188 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IIAEJBAH_01189 1.2e-146 cbiQ P cobalt transport
IIAEJBAH_01190 0.0 ykoD P abc transporter atp-binding protein
IIAEJBAH_01191 8e-94 S UPF0397 protein
IIAEJBAH_01192 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
IIAEJBAH_01193 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IIAEJBAH_01194 5.2e-98 metI P ABC transporter (Permease
IIAEJBAH_01195 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IIAEJBAH_01196 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IIAEJBAH_01197 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IIAEJBAH_01198 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IIAEJBAH_01199 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
IIAEJBAH_01200 1.8e-153 ET amino acid transport
IIAEJBAH_01201 3.8e-205 EGP Transmembrane secretion effector
IIAEJBAH_01202 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
IIAEJBAH_01203 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIAEJBAH_01204 5.3e-153 ET amino acid transport
IIAEJBAH_01205 1.6e-131 cbiO P ABC transporter
IIAEJBAH_01206 1.1e-136 P cobalt transport protein
IIAEJBAH_01207 4.3e-175 cbiM P PDGLE domain
IIAEJBAH_01208 3.4e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IIAEJBAH_01209 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IIAEJBAH_01210 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IIAEJBAH_01211 6.6e-78 ureE O enzyme active site formation
IIAEJBAH_01212 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IIAEJBAH_01213 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IIAEJBAH_01214 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IIAEJBAH_01215 6.8e-95 ureI S AmiS/UreI family transporter
IIAEJBAH_01216 2.1e-105 S Domain of unknown function (DUF4173)
IIAEJBAH_01217 1.8e-50 yhaI L Membrane
IIAEJBAH_01218 2.3e-129 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIAEJBAH_01219 1.8e-34 V protein secretion by the type I secretion system
IIAEJBAH_01220 1.2e-54 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIAEJBAH_01221 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIAEJBAH_01222 1.2e-32 V protein secretion by the type I secretion system
IIAEJBAH_01223 5.6e-161 K sequence-specific DNA binding
IIAEJBAH_01224 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
IIAEJBAH_01225 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IIAEJBAH_01226 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IIAEJBAH_01227 1.3e-246 trkA P Potassium transporter peripheral membrane component
IIAEJBAH_01228 1.2e-258 trkH P Cation transport protein
IIAEJBAH_01229 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IIAEJBAH_01230 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IIAEJBAH_01231 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IIAEJBAH_01232 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IIAEJBAH_01233 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IIAEJBAH_01234 7.8e-85 ykuL S CBS domain
IIAEJBAH_01235 3.5e-99 XK27_09740 S Phosphoesterase
IIAEJBAH_01236 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IIAEJBAH_01237 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IIAEJBAH_01238 7.6e-36 yneF S UPF0154 protein
IIAEJBAH_01239 3.7e-91 K transcriptional regulator
IIAEJBAH_01240 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IIAEJBAH_01243 8.8e-98 ybhL S Belongs to the BI1 family
IIAEJBAH_01244 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
IIAEJBAH_01245 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIAEJBAH_01246 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IIAEJBAH_01247 8.5e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIAEJBAH_01248 5.2e-59 L Integrase core domain protein
IIAEJBAH_01249 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIAEJBAH_01250 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IIAEJBAH_01251 2.1e-82 XK27_09675 K -acetyltransferase
IIAEJBAH_01252 5.7e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IIAEJBAH_01253 2.5e-23
IIAEJBAH_01254 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
IIAEJBAH_01255 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IIAEJBAH_01256 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IIAEJBAH_01257 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IIAEJBAH_01258 8.9e-95 ypsA S Belongs to the UPF0398 family
IIAEJBAH_01259 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IIAEJBAH_01260 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IIAEJBAH_01261 3.8e-205 EGP Transmembrane secretion effector
IIAEJBAH_01262 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
IIAEJBAH_01263 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIAEJBAH_01264 1.1e-30 ET amino acid transport
IIAEJBAH_01265 3.9e-122 L Transposase
IIAEJBAH_01266 1.2e-165 L integrase core domain
IIAEJBAH_01267 5.1e-259 pepC 3.4.22.40 E aminopeptidase
IIAEJBAH_01268 1.9e-77 yhaI L Membrane
IIAEJBAH_01269 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IIAEJBAH_01270 1.3e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIAEJBAH_01271 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
IIAEJBAH_01272 2.6e-76 S thiolester hydrolase activity
IIAEJBAH_01274 3.8e-40 K transcriptional
IIAEJBAH_01276 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IIAEJBAH_01277 1.6e-137 glcR K transcriptional regulator (DeoR family)
IIAEJBAH_01278 6.2e-35 cof Q phosphatase activity
IIAEJBAH_01279 6e-55 cof Q phosphatase activity
IIAEJBAH_01280 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
IIAEJBAH_01281 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
IIAEJBAH_01282 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
IIAEJBAH_01283 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IIAEJBAH_01284 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IIAEJBAH_01285 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IIAEJBAH_01286 6.8e-56 S TM2 domain
IIAEJBAH_01287 4.7e-43
IIAEJBAH_01289 1.4e-33 L Integrase core domain protein
IIAEJBAH_01290 1.7e-51 L transposition
IIAEJBAH_01291 3.2e-10 L transposase activity
IIAEJBAH_01292 4.4e-37 L Transposase
IIAEJBAH_01293 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IIAEJBAH_01294 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IIAEJBAH_01295 5.2e-142 cmpC S abc transporter atp-binding protein
IIAEJBAH_01296 0.0 WQ51_06230 S ABC transporter substrate binding protein
IIAEJBAH_01297 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IIAEJBAH_01298 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IIAEJBAH_01299 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
IIAEJBAH_01300 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IIAEJBAH_01301 9.8e-50 yajC U protein transport
IIAEJBAH_01302 1.9e-127 yeeN K transcriptional regulatory protein
IIAEJBAH_01303 1.1e-256 pgi 5.3.1.9 G Belongs to the GPI family
IIAEJBAH_01304 6.6e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
IIAEJBAH_01305 4.8e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IIAEJBAH_01306 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
IIAEJBAH_01307 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
IIAEJBAH_01308 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IIAEJBAH_01309 1.6e-127 adcB P ABC transporter (Permease
IIAEJBAH_01310 8.3e-136 adcC P ABC transporter, ATP-binding protein
IIAEJBAH_01311 3.1e-72 adcR K transcriptional
IIAEJBAH_01312 9.4e-223 EGP Major facilitator Superfamily
IIAEJBAH_01313 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIAEJBAH_01314 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IIAEJBAH_01315 6.4e-23
IIAEJBAH_01316 3.4e-62 oppF P Belongs to the ABC transporter superfamily
IIAEJBAH_01317 7.5e-62 oppF P Belongs to the ABC transporter superfamily
IIAEJBAH_01318 2.7e-41 oppD P Belongs to the ABC transporter superfamily
IIAEJBAH_01319 1.2e-62 oppD P Belongs to the ABC transporter superfamily
IIAEJBAH_01320 2.5e-32 oppD P Belongs to the ABC transporter superfamily
IIAEJBAH_01321 3e-27 oppD P Belongs to the ABC transporter superfamily
IIAEJBAH_01322 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIAEJBAH_01323 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIAEJBAH_01324 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIAEJBAH_01325 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIAEJBAH_01326 2e-138 oppA E ABC transporter substrate-binding protein
IIAEJBAH_01327 7e-10 oppA E ABC transporter substrate-binding protein
IIAEJBAH_01328 2.2e-273 sufB O assembly protein SufB
IIAEJBAH_01329 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
IIAEJBAH_01330 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IIAEJBAH_01331 6.3e-235 sufD O assembly protein SufD
IIAEJBAH_01332 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IIAEJBAH_01333 5.5e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
IIAEJBAH_01334 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IIAEJBAH_01335 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IIAEJBAH_01336 5.8e-275 glnP P ABC transporter
IIAEJBAH_01337 1e-123 glnQ E abc transporter atp-binding protein
IIAEJBAH_01338 5e-94 V VanZ like family
IIAEJBAH_01339 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IIAEJBAH_01340 6.5e-202 yhjX P Major Facilitator
IIAEJBAH_01341 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IIAEJBAH_01342 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIAEJBAH_01343 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IIAEJBAH_01344 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IIAEJBAH_01345 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IIAEJBAH_01346 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IIAEJBAH_01347 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IIAEJBAH_01348 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IIAEJBAH_01349 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IIAEJBAH_01350 3.8e-81 nrdI F Belongs to the NrdI family
IIAEJBAH_01351 6.3e-186 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IIAEJBAH_01352 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IIAEJBAH_01353 1.4e-42 F nucleotide catabolic process
IIAEJBAH_01354 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IIAEJBAH_01355 2e-177 prmA J Ribosomal protein L11 methyltransferase
IIAEJBAH_01356 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
IIAEJBAH_01357 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
IIAEJBAH_01358 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IIAEJBAH_01359 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IIAEJBAH_01360 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IIAEJBAH_01361 4.6e-149 ykuT M mechanosensitive ion channel
IIAEJBAH_01362 1.6e-77 sigH K DNA-templated transcription, initiation
IIAEJBAH_01363 6.5e-87
IIAEJBAH_01364 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IIAEJBAH_01365 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IIAEJBAH_01366 9.9e-19 S Domain of unknown function (DUF4649)
IIAEJBAH_01367 2.5e-169 L Transposase
IIAEJBAH_01368 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IIAEJBAH_01379 1.7e-60 hmpT S membrane
IIAEJBAH_01380 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
IIAEJBAH_01381 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IIAEJBAH_01382 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IIAEJBAH_01383 9.8e-298 dnaK O Heat shock 70 kDa protein
IIAEJBAH_01384 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IIAEJBAH_01385 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IIAEJBAH_01386 1.3e-102 acmA 3.2.1.17 NU amidase activity
IIAEJBAH_01387 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IIAEJBAH_01388 2.2e-38 ais G alpha-ribazole phosphatase activity
IIAEJBAH_01389 1.9e-242 XK27_08635 S UPF0210 protein
IIAEJBAH_01390 3.6e-39 gcvR T UPF0237 protein
IIAEJBAH_01391 3.3e-225 capA M Bacterial capsule synthesis protein
IIAEJBAH_01392 5.7e-91 tnp L Transposase
IIAEJBAH_01393 3.4e-75 isp2 S pathogenesis
IIAEJBAH_01395 4.9e-173
IIAEJBAH_01396 1.8e-38 S Helix-turn-helix domain
IIAEJBAH_01397 2.2e-224 int L Belongs to the 'phage' integrase family
IIAEJBAH_01399 0.0 res_1 3.1.21.5 S DEAD-like helicases superfamily
IIAEJBAH_01400 9.7e-227 sthIM 2.1.1.72 L DNA methylase
IIAEJBAH_01403 5.3e-18 D FtsK/SpoIIIE family
IIAEJBAH_01404 1.3e-134 D ftsk spoiiie
IIAEJBAH_01406 1.3e-154
IIAEJBAH_01407 1.7e-22
IIAEJBAH_01408 9.3e-184 L Phage integrase family
IIAEJBAH_01409 6.5e-90 3.6.4.12 K Divergent AAA domain protein
IIAEJBAH_01410 5.9e-24 3.6.4.12
IIAEJBAH_01411 2.5e-183 EGP Major facilitator Superfamily
IIAEJBAH_01412 2.4e-231 spaC2 V Lanthionine synthetase C family protein
IIAEJBAH_01413 0.0 S Lantibiotic dehydratase, C terminus
IIAEJBAH_01415 1.5e-35 K sequence-specific DNA binding
IIAEJBAH_01416 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IIAEJBAH_01417 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IIAEJBAH_01418 3.6e-57 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIAEJBAH_01419 1.6e-94 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIAEJBAH_01420 2.3e-31 K helix-turn-helix
IIAEJBAH_01421 3.4e-155 degV S DegV family
IIAEJBAH_01422 3.5e-91 yacP S RNA-binding protein containing a PIN domain
IIAEJBAH_01423 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIAEJBAH_01426 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IIAEJBAH_01427 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IIAEJBAH_01428 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
IIAEJBAH_01429 4.5e-143 S SseB protein N-terminal domain
IIAEJBAH_01430 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IIAEJBAH_01431 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IIAEJBAH_01432 4.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IIAEJBAH_01433 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IIAEJBAH_01434 0.0 clpC O Belongs to the ClpA ClpB family
IIAEJBAH_01435 2.4e-75 ctsR K Belongs to the CtsR family
IIAEJBAH_01436 1.1e-83 S Putative small multi-drug export protein
IIAEJBAH_01437 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IIAEJBAH_01438 6.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
IIAEJBAH_01441 1.9e-86 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IIAEJBAH_01442 7.3e-22 yocD 3.4.17.13 V carboxypeptidase activity
IIAEJBAH_01443 3.4e-58 L Integrase core domain protein
IIAEJBAH_01444 1.7e-96 S reductase
IIAEJBAH_01445 1.8e-26 badR K DNA-binding transcription factor activity
IIAEJBAH_01446 5.5e-36 XK27_02060 S Transglycosylase associated protein
IIAEJBAH_01447 5.7e-222 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IIAEJBAH_01448 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIAEJBAH_01453 1.9e-07
IIAEJBAH_01456 2.6e-10
IIAEJBAH_01461 1.1e-65 spxA_2 1.20.4.1 P Belongs to the ArsC family
IIAEJBAH_01462 2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IIAEJBAH_01463 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
IIAEJBAH_01464 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
IIAEJBAH_01465 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IIAEJBAH_01467 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IIAEJBAH_01469 1.2e-61 KT phosphorelay signal transduction system
IIAEJBAH_01470 7e-34 S Protein of unknown function (DUF3021)
IIAEJBAH_01471 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IIAEJBAH_01472 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IIAEJBAH_01473 8.2e-70 argR K Regulates arginine biosynthesis genes
IIAEJBAH_01474 2.6e-09 L Transposase
IIAEJBAH_01475 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IIAEJBAH_01476 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IIAEJBAH_01477 9.2e-141 1.1.1.169 H Ketopantoate reductase
IIAEJBAH_01478 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IIAEJBAH_01479 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IIAEJBAH_01480 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
IIAEJBAH_01481 2.3e-161 S CHAP domain
IIAEJBAH_01482 4.8e-76 L transposase activity
IIAEJBAH_01483 1.2e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IIAEJBAH_01484 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IIAEJBAH_01485 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IIAEJBAH_01486 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IIAEJBAH_01487 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIAEJBAH_01488 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IIAEJBAH_01489 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIAEJBAH_01490 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IIAEJBAH_01491 1e-142 recO L Involved in DNA repair and RecF pathway recombination
IIAEJBAH_01492 2.9e-218 araT 2.6.1.1 E Aminotransferase
IIAEJBAH_01493 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIAEJBAH_01494 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
IIAEJBAH_01495 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IIAEJBAH_01496 5.5e-139 mreC M Involved in formation and maintenance of cell shape
IIAEJBAH_01502 5.3e-11
IIAEJBAH_01514 9.2e-51 S Protein of unknown function (DUF3397)
IIAEJBAH_01515 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IIAEJBAH_01516 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IIAEJBAH_01517 7.3e-69 amiA E transmembrane transport
IIAEJBAH_01518 6.7e-81 amiA E transmembrane transport
IIAEJBAH_01519 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IIAEJBAH_01520 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IIAEJBAH_01521 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
IIAEJBAH_01522 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IIAEJBAH_01523 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIAEJBAH_01524 2e-186 jag S RNA-binding protein
IIAEJBAH_01525 1e-13 rpmH J Ribosomal protein L34
IIAEJBAH_01526 1.1e-83 L Transposase
IIAEJBAH_01527 6.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IIAEJBAH_01529 6.4e-57 L Integrase core domain protein
IIAEJBAH_01532 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
IIAEJBAH_01533 2e-09 L thioesterase
IIAEJBAH_01534 1.9e-141 S Macro domain protein
IIAEJBAH_01535 1.1e-50 trxA O Belongs to the thioredoxin family
IIAEJBAH_01536 1.6e-143 tatD L Hydrolase, tatd
IIAEJBAH_01537 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IIAEJBAH_01538 6.2e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IIAEJBAH_01540 4.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IIAEJBAH_01541 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IIAEJBAH_01542 2.4e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
IIAEJBAH_01543 6.9e-173 rmuC S RmuC domain protein
IIAEJBAH_01544 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
IIAEJBAH_01545 5.3e-142 purR 2.4.2.7 F operon repressor
IIAEJBAH_01546 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IIAEJBAH_01547 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IIAEJBAH_01548 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IIAEJBAH_01549 1.8e-187 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIAEJBAH_01550 6.4e-57 L Integrase core domain protein
IIAEJBAH_01551 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IIAEJBAH_01552 3.1e-30
IIAEJBAH_01553 1.5e-12
IIAEJBAH_01554 1.3e-87 S Fusaric acid resistance protein-like
IIAEJBAH_01555 8.5e-63 glnR K Transcriptional regulator
IIAEJBAH_01556 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
IIAEJBAH_01557 2.7e-40 pscB M CHAP domain protein
IIAEJBAH_01558 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIAEJBAH_01559 2.5e-33 ykzG S Belongs to the UPF0356 family
IIAEJBAH_01560 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
IIAEJBAH_01561 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IIAEJBAH_01562 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IIAEJBAH_01563 1.8e-114 azlC E AzlC protein
IIAEJBAH_01564 8.8e-48 azlD E branched-chain amino acid
IIAEJBAH_01565 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IIAEJBAH_01566 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IIAEJBAH_01567 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIAEJBAH_01568 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IIAEJBAH_01569 1e-93 cvpA S toxin biosynthetic process
IIAEJBAH_01570 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IIAEJBAH_01571 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IIAEJBAH_01576 2.5e-230 mutY L A G-specific adenine glycosylase
IIAEJBAH_01577 3.6e-41 XK27_05745
IIAEJBAH_01578 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
IIAEJBAH_01579 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIAEJBAH_01580 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IIAEJBAH_01582 3.1e-124 XK27_01040 S Pfam PF06570
IIAEJBAH_01583 2e-169 corA P COG0598 Mg2 and Co2 transporters
IIAEJBAH_01584 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IIAEJBAH_01587 7.7e-11 V 'abc transporter, ATP-binding protein
IIAEJBAH_01590 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
IIAEJBAH_01591 1.1e-83 comEB 3.5.4.12 F ComE operon protein 2
IIAEJBAH_01592 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IIAEJBAH_01593 3.4e-62 yqhY S protein conserved in bacteria
IIAEJBAH_01594 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IIAEJBAH_01595 1.7e-179 scrR K Transcriptional
IIAEJBAH_01596 4.1e-291 scrB 3.2.1.26 GH32 G invertase
IIAEJBAH_01597 0.0 scrA 2.7.1.211 G pts system
IIAEJBAH_01598 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
IIAEJBAH_01599 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
IIAEJBAH_01601 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IIAEJBAH_01602 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IIAEJBAH_01603 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IIAEJBAH_01604 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IIAEJBAH_01605 1.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIAEJBAH_01606 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IIAEJBAH_01607 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IIAEJBAH_01608 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
IIAEJBAH_01609 2.9e-18 yebC M Membrane
IIAEJBAH_01610 1.6e-79 yebC M Membrane
IIAEJBAH_01611 3.5e-17 KT response to antibiotic
IIAEJBAH_01612 8.5e-68 KT response to antibiotic
IIAEJBAH_01613 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
IIAEJBAH_01614 3.4e-57 liaI S membrane
IIAEJBAH_01615 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IIAEJBAH_01616 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IIAEJBAH_01617 9.3e-122 S Protein of unknown function (DUF554)
IIAEJBAH_01618 2.1e-129 ecsA_2 V abc transporter atp-binding protein
IIAEJBAH_01619 9.2e-284 XK27_00765
IIAEJBAH_01620 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IIAEJBAH_01621 6.9e-210 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IIAEJBAH_01622 4.5e-18 D nuclear chromosome segregation
IIAEJBAH_01623 2.8e-21 yhaI J Protein of unknown function (DUF805)
IIAEJBAH_01624 3.4e-58
IIAEJBAH_01625 2.2e-85
IIAEJBAH_01626 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IIAEJBAH_01627 8.1e-46 ftsL D cell division protein FtsL
IIAEJBAH_01628 0.0 ftsI 3.4.16.4 M penicillin-binding protein
IIAEJBAH_01629 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IIAEJBAH_01630 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IIAEJBAH_01632 4.8e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IIAEJBAH_01633 2.4e-66 yutD J protein conserved in bacteria
IIAEJBAH_01634 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IIAEJBAH_01635 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
IIAEJBAH_01637 0.0 mdlA V abc transporter atp-binding protein
IIAEJBAH_01638 0.0 mdlB V abc transporter atp-binding protein
IIAEJBAH_01639 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIAEJBAH_01640 4e-235 mesE M Transport protein ComB
IIAEJBAH_01642 1.4e-237 blpH 2.7.13.3 T protein histidine kinase activity
IIAEJBAH_01643 4.4e-132 agrA KT phosphorelay signal transduction system
IIAEJBAH_01646 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
IIAEJBAH_01651 6.7e-98 blpT
IIAEJBAH_01652 2.9e-28 blpT
IIAEJBAH_01653 3e-47 spiA K sequence-specific DNA binding
IIAEJBAH_01656 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IIAEJBAH_01657 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
IIAEJBAH_01658 5e-44 V CAAX protease self-immunity
IIAEJBAH_01659 4.6e-140 cppA E CppA N-terminal
IIAEJBAH_01660 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
IIAEJBAH_01661 4.4e-115 ybbL S abc transporter atp-binding protein
IIAEJBAH_01662 1.5e-127 ybbM S transport system, permease component
IIAEJBAH_01663 1.4e-33 D nuclear chromosome segregation
IIAEJBAH_01664 7.2e-46 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
IIAEJBAH_01665 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIAEJBAH_01666 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
IIAEJBAH_01667 0.0 pflB 2.3.1.54 C formate acetyltransferase'
IIAEJBAH_01668 1.3e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIAEJBAH_01670 8.8e-153 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IIAEJBAH_01671 1.4e-159 yxeN P ABC transporter (Permease
IIAEJBAH_01672 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
IIAEJBAH_01673 6.1e-08 S Protein of unknown function (DUF4059)
IIAEJBAH_01674 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IIAEJBAH_01675 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
IIAEJBAH_01676 2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IIAEJBAH_01677 8.4e-196 ylbL T Belongs to the peptidase S16 family
IIAEJBAH_01678 1.3e-184 yhcC S radical SAM protein
IIAEJBAH_01679 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
IIAEJBAH_01681 0.0 yjcE P NhaP-type Na H and K H antiporters
IIAEJBAH_01682 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
IIAEJBAH_01683 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
IIAEJBAH_01684 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IIAEJBAH_01687 2.4e-75 XK27_03180 T universal stress protein
IIAEJBAH_01688 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
IIAEJBAH_01689 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IIAEJBAH_01690 3.4e-100 pncA Q isochorismatase
IIAEJBAH_01691 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
IIAEJBAH_01692 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIAEJBAH_01693 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIAEJBAH_01694 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIAEJBAH_01695 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
IIAEJBAH_01696 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIAEJBAH_01697 1.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IIAEJBAH_01698 8.7e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIAEJBAH_01699 4e-59
IIAEJBAH_01700 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IIAEJBAH_01701 1.8e-98 yqeG S hydrolase of the HAD superfamily
IIAEJBAH_01702 2.4e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IIAEJBAH_01703 3.5e-49 yhbY J RNA-binding protein
IIAEJBAH_01704 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IIAEJBAH_01705 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IIAEJBAH_01706 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IIAEJBAH_01707 2e-140 yqeM Q Methyltransferase domain protein
IIAEJBAH_01708 1.2e-202 ylbM S Belongs to the UPF0348 family
IIAEJBAH_01709 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
IIAEJBAH_01710 6.5e-55
IIAEJBAH_01711 4.8e-11
IIAEJBAH_01712 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IIAEJBAH_01713 2.3e-133 ecsA V abc transporter atp-binding protein
IIAEJBAH_01714 1.6e-183 ecsB U ABC transporter
IIAEJBAH_01715 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
IIAEJBAH_01716 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IIAEJBAH_01718 7.7e-227 ytfP S Flavoprotein
IIAEJBAH_01719 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IIAEJBAH_01720 7.4e-64 XK27_02560 S cog cog2151
IIAEJBAH_01721 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
IIAEJBAH_01722 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
IIAEJBAH_01723 5.3e-119 K transcriptional regulator, MerR family
IIAEJBAH_01724 5.1e-47 L transposase activity
IIAEJBAH_01725 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IIAEJBAH_01726 6.1e-27
IIAEJBAH_01727 0.0 ctpE P E1-E2 ATPase
IIAEJBAH_01728 1.6e-55
IIAEJBAH_01729 1.5e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IIAEJBAH_01730 2.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
IIAEJBAH_01731 1.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IIAEJBAH_01732 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IIAEJBAH_01733 3e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
IIAEJBAH_01734 2.1e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IIAEJBAH_01735 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IIAEJBAH_01736 2.7e-73 copY K Copper transport repressor, CopY TcrY family
IIAEJBAH_01737 0.0 copA 3.6.3.54 P P-type ATPase
IIAEJBAH_01738 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
IIAEJBAH_01739 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IIAEJBAH_01740 6e-115 papP P ABC transporter (Permease
IIAEJBAH_01741 3e-106 P ABC transporter (Permease
IIAEJBAH_01742 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
IIAEJBAH_01743 1.1e-155 cjaA ET ABC transporter substrate-binding protein
IIAEJBAH_01747 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IIAEJBAH_01748 7.9e-120 ywaF S Integral membrane protein (intg_mem_TP0381)
IIAEJBAH_01749 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IIAEJBAH_01750 1.6e-200 yjbB G Permeases of the major facilitator superfamily
IIAEJBAH_01751 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IIAEJBAH_01752 7.8e-100 thiT S Thiamine transporter
IIAEJBAH_01753 1.9e-62 yjqA S Bacterial PH domain
IIAEJBAH_01754 2.3e-154 corA P CorA-like protein
IIAEJBAH_01755 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IIAEJBAH_01757 1e-41 yazA L endonuclease containing a URI domain
IIAEJBAH_01758 2.3e-139 yabB 2.1.1.223 L Methyltransferase
IIAEJBAH_01759 4.1e-22 nodB3 G polysaccharide deacetylase
IIAEJBAH_01760 1.7e-77 nodB3 G polysaccharide deacetylase
IIAEJBAH_01761 8.3e-142 plsC 2.3.1.51 I Acyltransferase
IIAEJBAH_01762 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IIAEJBAH_01763 0.0 comEC S Competence protein ComEC
IIAEJBAH_01764 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIAEJBAH_01765 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
IIAEJBAH_01766 3.3e-231 ytoI K transcriptional regulator containing CBS domains
IIAEJBAH_01767 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IIAEJBAH_01768 7.4e-164 rbn E Belongs to the UPF0761 family
IIAEJBAH_01769 3.7e-85 ccl S cog cog4708
IIAEJBAH_01770 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IIAEJBAH_01771 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IIAEJBAH_01772 1.9e-55 L Transposase
IIAEJBAH_01773 2.1e-74 S QueT transporter
IIAEJBAH_01774 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
IIAEJBAH_01775 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
IIAEJBAH_01776 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IIAEJBAH_01777 4.1e-37 ylqC L Belongs to the UPF0109 family
IIAEJBAH_01778 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IIAEJBAH_01779 0.0 ydaO E amino acid
IIAEJBAH_01780 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
IIAEJBAH_01781 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IIAEJBAH_01782 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
IIAEJBAH_01783 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IIAEJBAH_01784 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IIAEJBAH_01785 7.8e-171 murB 1.3.1.98 M cell wall formation
IIAEJBAH_01786 6.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IIAEJBAH_01787 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
IIAEJBAH_01788 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
IIAEJBAH_01789 2.3e-206 potD P spermidine putrescine ABC transporter
IIAEJBAH_01790 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
IIAEJBAH_01791 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
IIAEJBAH_01792 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
IIAEJBAH_01793 2.6e-95 GK ROK family
IIAEJBAH_01794 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IIAEJBAH_01795 3.9e-104 wecD M Acetyltransferase GNAT family
IIAEJBAH_01796 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIAEJBAH_01797 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
IIAEJBAH_01798 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
IIAEJBAH_01800 2.2e-58 lrgA S Effector of murein hydrolase LrgA
IIAEJBAH_01801 2.2e-117 lrgB M effector of murein hydrolase
IIAEJBAH_01802 2.6e-109 3.1.3.18 S IA, variant 1
IIAEJBAH_01803 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIAEJBAH_01804 2.8e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IIAEJBAH_01805 7.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
IIAEJBAH_01806 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IIAEJBAH_01807 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIAEJBAH_01808 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IIAEJBAH_01809 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
IIAEJBAH_01811 8.5e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
IIAEJBAH_01813 6.6e-30 ycaO O OsmC-like protein
IIAEJBAH_01814 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
IIAEJBAH_01817 3.6e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IIAEJBAH_01819 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IIAEJBAH_01820 2.4e-16 XK27_00735
IIAEJBAH_01821 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
IIAEJBAH_01822 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
IIAEJBAH_01823 2.6e-32 S CAAX amino terminal protease family protein
IIAEJBAH_01824 1.2e-55 V CAAX protease self-immunity
IIAEJBAH_01826 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IIAEJBAH_01827 2.9e-84 mutT 3.6.1.55 F Nudix family
IIAEJBAH_01828 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
IIAEJBAH_01829 7.2e-136 ET ABC transporter
IIAEJBAH_01830 3.4e-200 arcT 2.6.1.1 E Aminotransferase
IIAEJBAH_01831 7.9e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
IIAEJBAH_01832 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IIAEJBAH_01833 1.1e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IIAEJBAH_01834 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IIAEJBAH_01835 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IIAEJBAH_01836 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
IIAEJBAH_01837 5.4e-251 M Psort location CytoplasmicMembrane, score
IIAEJBAH_01838 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
IIAEJBAH_01839 1.2e-231
IIAEJBAH_01840 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IIAEJBAH_01841 7.6e-126 ycbB S Glycosyl transferase family 2
IIAEJBAH_01842 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
IIAEJBAH_01843 2.6e-220 amrA S polysaccharide biosynthetic process
IIAEJBAH_01844 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
IIAEJBAH_01845 1.3e-226 rgpA GT4 M Domain of unknown function (DUF1972)
IIAEJBAH_01846 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
IIAEJBAH_01847 1.1e-142 rgpC GM Transport permease protein
IIAEJBAH_01848 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IIAEJBAH_01849 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IIAEJBAH_01850 0.0 rgpF M Rhamnan synthesis protein F
IIAEJBAH_01851 6.2e-120 radC E Belongs to the UPF0758 family
IIAEJBAH_01852 1.6e-131 puuD T peptidase C26
IIAEJBAH_01853 3.6e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IIAEJBAH_01854 9e-59 XK27_04120 S Putative amino acid metabolism
IIAEJBAH_01855 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
IIAEJBAH_01856 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIAEJBAH_01857 5.8e-103 yjbK S Adenylate cyclase
IIAEJBAH_01858 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
IIAEJBAH_01859 1.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIAEJBAH_01860 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IIAEJBAH_01861 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IIAEJBAH_01862 3.7e-38 L transposase activity
IIAEJBAH_01863 1.4e-38 L transposase activity
IIAEJBAH_01864 9.3e-29 L transposition
IIAEJBAH_01865 4e-110 L PFAM Integrase catalytic region
IIAEJBAH_01866 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
IIAEJBAH_01867 2e-21 tatD L hydrolase, TatD family'
IIAEJBAH_01868 5.5e-23 oppF P Belongs to the ABC transporter superfamily
IIAEJBAH_01869 1.2e-24 oppF P Belongs to the ABC transporter superfamily
IIAEJBAH_01870 4.1e-158 L COG2801 Transposase and inactivated derivatives
IIAEJBAH_01871 8.1e-45 L Transposase
IIAEJBAH_01872 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IIAEJBAH_01873 1.1e-270 amiC P ABC transporter (Permease
IIAEJBAH_01874 2.4e-167 amiD P ABC transporter (Permease
IIAEJBAH_01875 2.2e-204 oppD P Belongs to the ABC transporter superfamily
IIAEJBAH_01876 4.3e-172 oppF P Belongs to the ABC transporter superfamily
IIAEJBAH_01877 9e-131 V ATPase activity
IIAEJBAH_01878 9.8e-121 skfE V abc transporter atp-binding protein
IIAEJBAH_01879 8.6e-63 yvoA_1 K Transcriptional
IIAEJBAH_01880 5.3e-147 supH S overlaps another CDS with the same product name
IIAEJBAH_01881 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
IIAEJBAH_01882 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IIAEJBAH_01883 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IIAEJBAH_01884 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
IIAEJBAH_01885 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIAEJBAH_01886 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IIAEJBAH_01887 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IIAEJBAH_01888 9e-133 stp 3.1.3.16 T phosphatase
IIAEJBAH_01889 1.7e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
IIAEJBAH_01890 9.1e-119 yvqF KT membrane
IIAEJBAH_01891 1.9e-173 vraS 2.7.13.3 T Histidine kinase
IIAEJBAH_01892 8.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIAEJBAH_01895 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IIAEJBAH_01896 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IIAEJBAH_01897 8.6e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IIAEJBAH_01898 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IIAEJBAH_01899 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAEJBAH_01900 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAEJBAH_01901 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IIAEJBAH_01902 6.4e-62 L Transposase
IIAEJBAH_01903 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
IIAEJBAH_01904 4.3e-40 V abc transporter atp-binding protein
IIAEJBAH_01905 2.5e-101 V abc transporter atp-binding protein
IIAEJBAH_01906 5.1e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IIAEJBAH_01907 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IIAEJBAH_01908 1.2e-25 L transposition
IIAEJBAH_01909 2.7e-08 L Integrase core domain protein
IIAEJBAH_01910 2.3e-184 galR K Transcriptional regulator
IIAEJBAH_01911 3.7e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IIAEJBAH_01912 1.3e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IIAEJBAH_01913 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IIAEJBAH_01914 2.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IIAEJBAH_01915 0.0 lacS G transporter
IIAEJBAH_01916 0.0 lacL 3.2.1.23 G -beta-galactosidase
IIAEJBAH_01917 1.3e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IIAEJBAH_01918 0.0 sbcC L ATPase involved in DNA repair
IIAEJBAH_01919 1.4e-84
IIAEJBAH_01921 1.8e-87 L transposase activity
IIAEJBAH_01922 1.4e-150 L Integrase core domain protein
IIAEJBAH_01923 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IIAEJBAH_01925 5.5e-258 I radical SAM domain protein
IIAEJBAH_01926 1.2e-176 EGP Major Facilitator Superfamily
IIAEJBAH_01927 3.9e-110 C Fe-S oxidoreductases
IIAEJBAH_01929 1.1e-151 V MatE
IIAEJBAH_01930 1.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
IIAEJBAH_01931 5e-161 hrtB V MacB-like periplasmic core domain
IIAEJBAH_01933 0.0 M family 8
IIAEJBAH_01934 2.7e-09
IIAEJBAH_01935 5.6e-08
IIAEJBAH_01936 5.8e-109 MA20_06410 E LysE type translocator
IIAEJBAH_01937 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
IIAEJBAH_01938 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
IIAEJBAH_01939 1e-137
IIAEJBAH_01940 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIAEJBAH_01941 4.5e-61
IIAEJBAH_01943 9.3e-72 S Signal peptide protein, YSIRK family
IIAEJBAH_01944 1.4e-54 K response regulator
IIAEJBAH_01945 1.1e-37 BP1961 P nitric oxide dioxygenase activity
IIAEJBAH_01947 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
IIAEJBAH_01948 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IIAEJBAH_01949 6.8e-161 yvgN C reductase
IIAEJBAH_01950 3e-102 yoaK S Protein of unknown function (DUF1275)
IIAEJBAH_01951 1.4e-110 drgA C Nitroreductase
IIAEJBAH_01952 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIAEJBAH_01953 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
IIAEJBAH_01954 5.6e-77 ywnA K Transcriptional regulator
IIAEJBAH_01955 9.5e-150 1.13.11.2 S glyoxalase
IIAEJBAH_01956 5.1e-110 XK27_02070 S nitroreductase
IIAEJBAH_01957 4e-227 yfnA E amino acid
IIAEJBAH_01959 4.8e-25 csbD K CsbD-like
IIAEJBAH_01960 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
IIAEJBAH_01961 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
IIAEJBAH_01962 1.7e-235 brnQ E Component of the transport system for branched-chain amino acids
IIAEJBAH_01963 2.2e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIAEJBAH_01964 4.5e-247 norM V Multidrug efflux pump
IIAEJBAH_01965 2.1e-192 pbuX F xanthine permease
IIAEJBAH_01967 3.2e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IIAEJBAH_01968 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIAEJBAH_01969 6.2e-166 T Histidine kinase
IIAEJBAH_01970 1.9e-133 macB2 V ABC transporter, ATP-binding protein
IIAEJBAH_01971 0.0 V ABC transporter (permease)
IIAEJBAH_01972 6.1e-93 XK27_05000 S metal cluster binding
IIAEJBAH_01973 2.6e-30 liaI KT membrane
IIAEJBAH_01974 1.4e-15 liaI KT membrane
IIAEJBAH_01975 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
IIAEJBAH_01976 3.7e-122 S An automated process has identified a potential problem with this gene model
IIAEJBAH_01978 3.3e-186 L Transposase
IIAEJBAH_01979 0.0 copB 3.6.3.4 P P-type ATPase
IIAEJBAH_01980 3.3e-222 L Transposase
IIAEJBAH_01981 4.4e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IIAEJBAH_01982 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IIAEJBAH_01983 3.5e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IIAEJBAH_01984 3.3e-98 cysE 2.3.1.30 E serine acetyltransferase
IIAEJBAH_01985 3.3e-10 L Transposase
IIAEJBAH_01986 2.9e-31 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)