ORF_ID e_value Gene_name EC_number CAZy COGs Description
EDKNDPFM_00001 1.8e-111 L PFAM Integrase, catalytic core
EDKNDPFM_00002 3.3e-09 L PFAM Integrase, catalytic core
EDKNDPFM_00003 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
EDKNDPFM_00004 8.1e-64 6.3.2.2 H gamma-glutamylcysteine synthetase
EDKNDPFM_00005 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
EDKNDPFM_00007 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
EDKNDPFM_00008 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
EDKNDPFM_00010 5.7e-217 S MvaI/BcnI restriction endonuclease family
EDKNDPFM_00012 7.7e-13
EDKNDPFM_00013 5e-31 S Hypothetical protein (DUF2513)
EDKNDPFM_00014 6.5e-31
EDKNDPFM_00015 1e-39
EDKNDPFM_00020 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
EDKNDPFM_00021 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EDKNDPFM_00022 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
EDKNDPFM_00023 2.5e-29 K Putative DNA-binding domain
EDKNDPFM_00024 6.7e-98 blpT
EDKNDPFM_00025 2.9e-28 blpT
EDKNDPFM_00026 3e-47 spiA K sequence-specific DNA binding
EDKNDPFM_00029 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EDKNDPFM_00030 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EDKNDPFM_00031 5e-44 V CAAX protease self-immunity
EDKNDPFM_00032 4.6e-140 cppA E CppA N-terminal
EDKNDPFM_00033 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
EDKNDPFM_00034 1.2e-117 ybbL S abc transporter atp-binding protein
EDKNDPFM_00035 1.5e-127 ybbM S transport system, permease component
EDKNDPFM_00036 2.9e-87 D nuclear chromosome segregation
EDKNDPFM_00037 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
EDKNDPFM_00038 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EDKNDPFM_00039 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
EDKNDPFM_00040 0.0 pflB 2.3.1.54 C formate acetyltransferase'
EDKNDPFM_00041 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDKNDPFM_00043 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EDKNDPFM_00044 1e-162 yxeN P ABC transporter (Permease
EDKNDPFM_00045 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
EDKNDPFM_00046 1.9e-09 S Protein of unknown function (DUF4059)
EDKNDPFM_00047 3.2e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EDKNDPFM_00048 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
EDKNDPFM_00049 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EDKNDPFM_00050 2.2e-196 ylbL T Belongs to the peptidase S16 family
EDKNDPFM_00051 3.8e-184 yhcC S radical SAM protein
EDKNDPFM_00052 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
EDKNDPFM_00054 0.0 yjcE P NhaP-type Na H and K H antiporters
EDKNDPFM_00055 1.2e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
EDKNDPFM_00056 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
EDKNDPFM_00057 6.3e-156 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EDKNDPFM_00060 2.4e-75 XK27_03180 T universal stress protein
EDKNDPFM_00061 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
EDKNDPFM_00062 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EDKNDPFM_00063 6.8e-101 pncA Q isochorismatase
EDKNDPFM_00064 1.5e-124 hlpA M Belongs to the NlpA lipoprotein family
EDKNDPFM_00065 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EDKNDPFM_00066 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDKNDPFM_00067 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDKNDPFM_00068 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EDKNDPFM_00069 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EDKNDPFM_00070 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EDKNDPFM_00071 1.2e-58
EDKNDPFM_00072 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EDKNDPFM_00073 1.8e-98 yqeG S hydrolase of the HAD superfamily
EDKNDPFM_00074 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EDKNDPFM_00075 3.5e-49 yhbY J RNA-binding protein
EDKNDPFM_00076 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EDKNDPFM_00077 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EDKNDPFM_00078 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EDKNDPFM_00079 2e-140 yqeM Q Methyltransferase domain protein
EDKNDPFM_00080 6.9e-206 ylbM S Belongs to the UPF0348 family
EDKNDPFM_00081 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
EDKNDPFM_00082 2.4e-170 L Integrase
EDKNDPFM_00084 7.3e-107
EDKNDPFM_00085 2.6e-55 S CD20-like family
EDKNDPFM_00086 5.6e-12
EDKNDPFM_00087 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EDKNDPFM_00088 2.3e-133 ecsA V abc transporter atp-binding protein
EDKNDPFM_00089 2.7e-183 ecsB U ABC transporter
EDKNDPFM_00090 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
EDKNDPFM_00091 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EDKNDPFM_00093 7.7e-227 ytfP S Flavoprotein
EDKNDPFM_00094 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EDKNDPFM_00095 7.4e-64 XK27_02560 S cog cog2151
EDKNDPFM_00096 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
EDKNDPFM_00097 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
EDKNDPFM_00098 2.7e-129 K transcriptional regulator, MerR family
EDKNDPFM_00099 9.7e-28 L transposase activity
EDKNDPFM_00100 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EDKNDPFM_00101 3.9e-26
EDKNDPFM_00102 0.0 ctpE P E1-E2 ATPase
EDKNDPFM_00103 3.2e-56
EDKNDPFM_00104 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
EDKNDPFM_00105 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EDKNDPFM_00106 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
EDKNDPFM_00107 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EDKNDPFM_00108 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EDKNDPFM_00109 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
EDKNDPFM_00110 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EDKNDPFM_00111 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EDKNDPFM_00112 5.2e-72 copY K Copper transport repressor, CopY TcrY family
EDKNDPFM_00113 0.0 copA 3.6.3.54 P P-type ATPase
EDKNDPFM_00114 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
EDKNDPFM_00115 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EDKNDPFM_00116 6e-115 papP P ABC transporter (Permease
EDKNDPFM_00117 3e-106 P ABC transporter (Permease
EDKNDPFM_00118 7.6e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDKNDPFM_00119 1.1e-155 cjaA ET ABC transporter substrate-binding protein
EDKNDPFM_00123 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EDKNDPFM_00124 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
EDKNDPFM_00125 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EDKNDPFM_00126 1.9e-201 yjbB G Permeases of the major facilitator superfamily
EDKNDPFM_00127 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EDKNDPFM_00128 7.8e-100 thiT S Thiamine transporter
EDKNDPFM_00129 1.9e-62 yjqA S Bacterial PH domain
EDKNDPFM_00130 2.3e-154 corA P CorA-like protein
EDKNDPFM_00131 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EDKNDPFM_00132 1e-41 yazA L endonuclease containing a URI domain
EDKNDPFM_00133 2.3e-139 yabB 2.1.1.223 L Methyltransferase
EDKNDPFM_00134 4.1e-22 nodB3 G polysaccharide deacetylase
EDKNDPFM_00135 1.7e-77 nodB3 G polysaccharide deacetylase
EDKNDPFM_00136 1.3e-142 plsC 2.3.1.51 I Acyltransferase
EDKNDPFM_00137 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EDKNDPFM_00138 0.0 comEC S Competence protein ComEC
EDKNDPFM_00139 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EDKNDPFM_00140 7e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
EDKNDPFM_00141 3.6e-230 ytoI K transcriptional regulator containing CBS domains
EDKNDPFM_00142 2.1e-165 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
EDKNDPFM_00143 7.4e-164 rbn E Belongs to the UPF0761 family
EDKNDPFM_00144 3.7e-85 ccl S cog cog4708
EDKNDPFM_00145 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EDKNDPFM_00146 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EDKNDPFM_00147 1.9e-55 L Transposase
EDKNDPFM_00148 2.1e-74 S QueT transporter
EDKNDPFM_00149 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
EDKNDPFM_00150 5.8e-97 tehB 2.1.1.265 PQ tellurite resistance protein tehb
EDKNDPFM_00151 1.8e-65 tehB 2.1.1.265 Q Methyltransferase
EDKNDPFM_00152 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EDKNDPFM_00153 4.1e-37 ylqC L Belongs to the UPF0109 family
EDKNDPFM_00154 1.6e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EDKNDPFM_00155 0.0 ydaO E amino acid
EDKNDPFM_00156 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
EDKNDPFM_00157 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EDKNDPFM_00158 3.5e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EDKNDPFM_00159 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EDKNDPFM_00160 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EDKNDPFM_00161 7.8e-171 murB 1.3.1.98 M cell wall formation
EDKNDPFM_00162 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EDKNDPFM_00163 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
EDKNDPFM_00164 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
EDKNDPFM_00165 2.3e-206 potD P spermidine putrescine ABC transporter
EDKNDPFM_00166 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
EDKNDPFM_00167 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
EDKNDPFM_00168 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
EDKNDPFM_00169 3.7e-62 GK ROK family
EDKNDPFM_00170 5.5e-46 GK ROK family
EDKNDPFM_00171 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EDKNDPFM_00172 3.9e-104 wecD M Acetyltransferase GNAT family
EDKNDPFM_00173 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EDKNDPFM_00174 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
EDKNDPFM_00175 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
EDKNDPFM_00177 2.2e-58 lrgA S Effector of murein hydrolase LrgA
EDKNDPFM_00178 2.2e-117 lrgB M effector of murein hydrolase
EDKNDPFM_00179 2.6e-109 3.1.3.18 S IA, variant 1
EDKNDPFM_00180 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EDKNDPFM_00181 3e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EDKNDPFM_00182 2e-115 serB 3.1.3.3 E phosphoserine phosphatase
EDKNDPFM_00183 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EDKNDPFM_00184 7.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDKNDPFM_00185 1.4e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDKNDPFM_00186 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
EDKNDPFM_00188 8.5e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
EDKNDPFM_00190 6.6e-30 ycaO O OsmC-like protein
EDKNDPFM_00191 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
EDKNDPFM_00194 3.6e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EDKNDPFM_00196 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EDKNDPFM_00197 1.1e-16 XK27_00735
EDKNDPFM_00198 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDKNDPFM_00199 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
EDKNDPFM_00200 2.4e-33 S CAAX amino terminal protease family protein
EDKNDPFM_00201 4.3e-82 S CAAX amino terminal protease family protein
EDKNDPFM_00203 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EDKNDPFM_00204 2.9e-84 mutT 3.6.1.55 F Nudix family
EDKNDPFM_00205 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
EDKNDPFM_00206 9.4e-136 ET ABC transporter
EDKNDPFM_00207 2.1e-202 arcT 2.6.1.1 E Aminotransferase
EDKNDPFM_00208 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
EDKNDPFM_00209 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EDKNDPFM_00210 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EDKNDPFM_00211 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EDKNDPFM_00212 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
EDKNDPFM_00213 1.4e-251 M Psort location CytoplasmicMembrane, score
EDKNDPFM_00214 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EDKNDPFM_00215 3.2e-245
EDKNDPFM_00216 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EDKNDPFM_00217 7.6e-126 ycbB S Glycosyl transferase family 2
EDKNDPFM_00218 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
EDKNDPFM_00219 2.6e-220 amrA S polysaccharide biosynthetic process
EDKNDPFM_00220 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
EDKNDPFM_00221 1.3e-226 rgpA GT4 M Domain of unknown function (DUF1972)
EDKNDPFM_00222 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
EDKNDPFM_00223 2.8e-143 rgpC GM Transport permease protein
EDKNDPFM_00224 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EDKNDPFM_00225 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EDKNDPFM_00226 0.0 rgpF M Rhamnan synthesis protein F
EDKNDPFM_00227 2.4e-119 radC E Belongs to the UPF0758 family
EDKNDPFM_00228 7.2e-132 puuD T peptidase C26
EDKNDPFM_00229 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EDKNDPFM_00230 9e-59 XK27_04120 S Putative amino acid metabolism
EDKNDPFM_00231 1.2e-205 iscS 2.8.1.7 E Cysteine desulfurase
EDKNDPFM_00232 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EDKNDPFM_00233 1.5e-103 yjbK S Adenylate cyclase
EDKNDPFM_00234 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
EDKNDPFM_00235 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EDKNDPFM_00236 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EDKNDPFM_00237 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EDKNDPFM_00238 8.9e-18 L transposase activity
EDKNDPFM_00239 1.1e-23 L transposase activity
EDKNDPFM_00240 1e-110 L Integrase core domain protein
EDKNDPFM_00241 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
EDKNDPFM_00242 1.4e-40 tatD L Hydrolase, tatd
EDKNDPFM_00243 3.8e-45 oppF P Belongs to the ABC transporter superfamily
EDKNDPFM_00244 1.2e-24 oppF P Belongs to the ABC transporter superfamily
EDKNDPFM_00245 4.1e-158 L COG2801 Transposase and inactivated derivatives
EDKNDPFM_00246 8.1e-45 L Transposase
EDKNDPFM_00247 4.1e-237 amiA E ABC transporter, substrate-binding protein, family 5
EDKNDPFM_00248 2.1e-277 amiC P ABC transporter (Permease
EDKNDPFM_00249 4.9e-168 amiD P ABC transporter (Permease
EDKNDPFM_00250 2.2e-204 oppD P Belongs to the ABC transporter superfamily
EDKNDPFM_00251 4.3e-172 oppF P Belongs to the ABC transporter superfamily
EDKNDPFM_00252 3.3e-133 V ATPase activity
EDKNDPFM_00253 1.1e-119 skfE V abc transporter atp-binding protein
EDKNDPFM_00254 8.6e-63 yvoA_1 K Transcriptional
EDKNDPFM_00255 8.5e-145 supH S overlaps another CDS with the same product name
EDKNDPFM_00256 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
EDKNDPFM_00257 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EDKNDPFM_00258 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EDKNDPFM_00259 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
EDKNDPFM_00260 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EDKNDPFM_00261 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EDKNDPFM_00262 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EDKNDPFM_00263 2e-132 stp 3.1.3.16 T phosphatase
EDKNDPFM_00264 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
EDKNDPFM_00265 3.7e-120 yvqF KT membrane
EDKNDPFM_00266 5.8e-175 vraS 2.7.13.3 T Histidine kinase
EDKNDPFM_00267 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EDKNDPFM_00270 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EDKNDPFM_00271 2.1e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EDKNDPFM_00272 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EDKNDPFM_00273 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EDKNDPFM_00274 7e-119 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDKNDPFM_00275 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDKNDPFM_00276 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDKNDPFM_00277 6.4e-62 L Transposase
EDKNDPFM_00278 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
EDKNDPFM_00279 4.3e-40 V abc transporter atp-binding protein
EDKNDPFM_00280 2.5e-101 V abc transporter atp-binding protein
EDKNDPFM_00281 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
EDKNDPFM_00282 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
EDKNDPFM_00283 1.2e-25 L transposition
EDKNDPFM_00284 2.7e-08 L Integrase core domain protein
EDKNDPFM_00285 2.3e-184 galR K Transcriptional regulator
EDKNDPFM_00286 8.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EDKNDPFM_00287 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EDKNDPFM_00288 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EDKNDPFM_00289 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EDKNDPFM_00290 0.0 lacS G transporter
EDKNDPFM_00291 0.0 lacL 3.2.1.23 G -beta-galactosidase
EDKNDPFM_00292 1.5e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EDKNDPFM_00293 0.0 sbcC L ATPase involved in DNA repair
EDKNDPFM_00294 2.8e-85
EDKNDPFM_00296 1.8e-87 L transposase activity
EDKNDPFM_00297 1.4e-150 L Integrase core domain protein
EDKNDPFM_00298 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EDKNDPFM_00300 1.6e-257 I radical SAM domain protein
EDKNDPFM_00301 1.2e-176 EGP Major Facilitator Superfamily
EDKNDPFM_00302 3.9e-110 C Fe-S oxidoreductases
EDKNDPFM_00304 1.1e-151 V MatE
EDKNDPFM_00305 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
EDKNDPFM_00306 1.5e-162 hrtB V MacB-like periplasmic core domain
EDKNDPFM_00308 0.0 M family 8
EDKNDPFM_00309 2.7e-09
EDKNDPFM_00310 5.6e-08
EDKNDPFM_00311 5.8e-109 MA20_06410 E LysE type translocator
EDKNDPFM_00312 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
EDKNDPFM_00313 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
EDKNDPFM_00314 1e-137
EDKNDPFM_00315 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDKNDPFM_00316 4.5e-61
EDKNDPFM_00317 9.3e-72 S Signal peptide protein, YSIRK family
EDKNDPFM_00318 1.4e-54 K response regulator
EDKNDPFM_00319 1.1e-37 BP1961 P nitric oxide dioxygenase activity
EDKNDPFM_00321 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
EDKNDPFM_00322 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EDKNDPFM_00323 6.8e-161 yvgN C reductase
EDKNDPFM_00325 3e-102 yoaK S Protein of unknown function (DUF1275)
EDKNDPFM_00326 1.4e-110 drgA C Nitroreductase
EDKNDPFM_00327 5.6e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EDKNDPFM_00328 8.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
EDKNDPFM_00329 4.7e-76 ywnA K Transcriptional regulator
EDKNDPFM_00330 9.5e-150 1.13.11.2 S glyoxalase
EDKNDPFM_00331 5.1e-110 XK27_02070 S nitroreductase
EDKNDPFM_00333 2.1e-71 ydhF S Aldo keto reductase
EDKNDPFM_00334 1.1e-59 ydhF S Aldo keto reductase
EDKNDPFM_00335 3.9e-82 K WHG domain
EDKNDPFM_00336 3.2e-91 V abc transporter atp-binding protein
EDKNDPFM_00337 5.9e-23 P FtsX-like permease family
EDKNDPFM_00338 2.4e-40 S Sugar efflux transporter for intercellular exchange
EDKNDPFM_00339 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
EDKNDPFM_00340 8.1e-161 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
EDKNDPFM_00341 1.8e-161 ET ABC transporter substrate-binding protein
EDKNDPFM_00342 6.1e-107 ytmL P ABC transporter (Permease
EDKNDPFM_00343 3e-114 yxeN P ABC transporter, permease protein
EDKNDPFM_00344 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
EDKNDPFM_00347 1.6e-21 L Integrase core domain protein
EDKNDPFM_00348 1.1e-139 S dextransucrase activity
EDKNDPFM_00349 4.9e-228 S dextransucrase activity
EDKNDPFM_00350 6.2e-228 yfnA E amino acid
EDKNDPFM_00352 9.6e-26 csbD K CsbD-like
EDKNDPFM_00353 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
EDKNDPFM_00354 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
EDKNDPFM_00355 5.6e-234 brnQ E Component of the transport system for branched-chain amino acids
EDKNDPFM_00356 6.7e-129 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EDKNDPFM_00357 6.7e-35 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EDKNDPFM_00358 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
EDKNDPFM_00359 1.5e-78 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
EDKNDPFM_00360 5.6e-145 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
EDKNDPFM_00361 3e-115 yxeQ S MmgE/PrpD family
EDKNDPFM_00362 4.1e-58 yxeL K Acetyltransferase (GNAT) domain
EDKNDPFM_00363 4.1e-63 yxeN U ABC transporter, permease protein
EDKNDPFM_00364 7.3e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
EDKNDPFM_00365 2.9e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
EDKNDPFM_00366 3.5e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
EDKNDPFM_00367 6.3e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EDKNDPFM_00368 3.4e-247 norM V Multidrug efflux pump
EDKNDPFM_00369 1.2e-198 pbuX F xanthine permease
EDKNDPFM_00371 3.2e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EDKNDPFM_00372 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDKNDPFM_00373 6.2e-166 T Histidine kinase
EDKNDPFM_00374 3.2e-133 macB2 V ABC transporter, ATP-binding protein
EDKNDPFM_00375 0.0 V ABC transporter (permease)
EDKNDPFM_00376 6.1e-93 XK27_05000 S metal cluster binding
EDKNDPFM_00377 2.6e-30 liaI KT membrane
EDKNDPFM_00378 1.4e-15 liaI KT membrane
EDKNDPFM_00379 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
EDKNDPFM_00380 3.7e-122 S An automated process has identified a potential problem with this gene model
EDKNDPFM_00382 7.2e-242 amiA E ABC transporter, substrate-binding protein, family 5
EDKNDPFM_00383 9.7e-149 L Transposase
EDKNDPFM_00384 4.6e-42 3.6.1.55 F NUDIX domain
EDKNDPFM_00385 6e-152 mutR K Transcriptional activator, Rgg GadR MutR family
EDKNDPFM_00386 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
EDKNDPFM_00387 6.6e-213 EGP Major facilitator Superfamily
EDKNDPFM_00391 5.7e-158 XK27_09825 V abc transporter atp-binding protein
EDKNDPFM_00392 1.4e-133 yvfS V ABC-2 type transporter
EDKNDPFM_00393 1.5e-192 desK 2.7.13.3 T Histidine kinase
EDKNDPFM_00394 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EDKNDPFM_00395 3.6e-97 S transport system, permease component
EDKNDPFM_00396 3.5e-33 S transport system, permease component
EDKNDPFM_00397 1.1e-144 S ABC-2 family transporter protein
EDKNDPFM_00398 7.4e-26
EDKNDPFM_00399 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
EDKNDPFM_00400 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
EDKNDPFM_00401 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
EDKNDPFM_00402 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EDKNDPFM_00403 4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EDKNDPFM_00404 6.3e-23
EDKNDPFM_00405 3e-13
EDKNDPFM_00406 2.4e-92 pat 2.3.1.183 M acetyltransferase
EDKNDPFM_00407 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EDKNDPFM_00408 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EDKNDPFM_00409 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EDKNDPFM_00410 0.0 smc D Required for chromosome condensation and partitioning
EDKNDPFM_00411 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EDKNDPFM_00412 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EDKNDPFM_00413 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EDKNDPFM_00415 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
EDKNDPFM_00416 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EDKNDPFM_00418 2e-86 S ECF-type riboflavin transporter, S component
EDKNDPFM_00419 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EDKNDPFM_00420 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EDKNDPFM_00421 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
EDKNDPFM_00422 1.9e-294 yfmM S abc transporter atp-binding protein
EDKNDPFM_00423 3.4e-258 noxE P NADH oxidase
EDKNDPFM_00424 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EDKNDPFM_00425 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EDKNDPFM_00426 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
EDKNDPFM_00427 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
EDKNDPFM_00428 9e-165 ypuA S secreted protein
EDKNDPFM_00429 8.8e-60 L Transposase (IS116 IS110 IS902 family)
EDKNDPFM_00430 3.6e-70 L Transposase (IS116 IS110 IS902 family)
EDKNDPFM_00432 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EDKNDPFM_00433 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EDKNDPFM_00434 7.2e-33 nrdH O Glutaredoxin
EDKNDPFM_00435 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EDKNDPFM_00436 4.3e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
EDKNDPFM_00437 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
EDKNDPFM_00438 7.9e-39 ptsH G phosphocarrier protein Hpr
EDKNDPFM_00439 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EDKNDPFM_00440 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EDKNDPFM_00441 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EDKNDPFM_00442 1.7e-35 XK27_09805 S MORN repeat protein
EDKNDPFM_00443 0.0 XK27_09800 I Acyltransferase
EDKNDPFM_00444 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EDKNDPFM_00445 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
EDKNDPFM_00446 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EDKNDPFM_00447 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
EDKNDPFM_00448 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EDKNDPFM_00449 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EDKNDPFM_00450 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EDKNDPFM_00451 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EDKNDPFM_00452 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EDKNDPFM_00453 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EDKNDPFM_00454 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
EDKNDPFM_00455 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EDKNDPFM_00456 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EDKNDPFM_00457 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EDKNDPFM_00458 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EDKNDPFM_00459 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EDKNDPFM_00460 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EDKNDPFM_00461 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EDKNDPFM_00462 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EDKNDPFM_00463 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EDKNDPFM_00464 2.5e-23 rpmD J ribosomal protein l30
EDKNDPFM_00465 4.4e-58 rplO J binds to the 23S rRNA
EDKNDPFM_00466 1.4e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EDKNDPFM_00467 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EDKNDPFM_00468 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EDKNDPFM_00469 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EDKNDPFM_00470 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EDKNDPFM_00471 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EDKNDPFM_00472 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDKNDPFM_00473 3.3e-62 rplQ J ribosomal protein l17
EDKNDPFM_00474 2e-94 L PFAM Integrase, catalytic core
EDKNDPFM_00475 2e-35 L PFAM Integrase, catalytic core
EDKNDPFM_00478 3.3e-95 ywlG S Belongs to the UPF0340 family
EDKNDPFM_00479 1.2e-85 treR K trehalose operon
EDKNDPFM_00480 5.8e-21 treR K DNA-binding transcription factor activity
EDKNDPFM_00481 1.4e-54 treB 2.7.1.201 G PTS System
EDKNDPFM_00482 2.3e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EDKNDPFM_00483 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EDKNDPFM_00484 1.8e-37 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EDKNDPFM_00485 0.0 pepO 3.4.24.71 O Peptidase family M13
EDKNDPFM_00486 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
EDKNDPFM_00487 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EDKNDPFM_00488 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EDKNDPFM_00489 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
EDKNDPFM_00490 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EDKNDPFM_00491 8.3e-279 thrC 4.2.3.1 E Threonine synthase
EDKNDPFM_00492 9.3e-226 norN V Mate efflux family protein
EDKNDPFM_00493 1.4e-57 asp S cog cog1302
EDKNDPFM_00494 6.4e-304 yloV S kinase related to dihydroxyacetone kinase
EDKNDPFM_00495 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EDKNDPFM_00496 2.6e-277 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EDKNDPFM_00497 3.1e-08 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EDKNDPFM_00498 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
EDKNDPFM_00499 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
EDKNDPFM_00500 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EDKNDPFM_00501 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EDKNDPFM_00502 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EDKNDPFM_00503 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDKNDPFM_00504 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EDKNDPFM_00505 2.9e-68 S cog cog4699
EDKNDPFM_00506 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EDKNDPFM_00507 9.2e-153 cglB NU type II secretion system
EDKNDPFM_00508 8.5e-43 comGC U Required for transformation and DNA binding
EDKNDPFM_00509 1.8e-57 cglD NU Competence protein
EDKNDPFM_00510 1.4e-15 NU Type II secretory pathway pseudopilin
EDKNDPFM_00511 4e-72 comGF U Competence protein ComGF
EDKNDPFM_00512 6.8e-13 comGF U Putative Competence protein ComGF
EDKNDPFM_00513 5.9e-177 ytxK 2.1.1.72 L DNA methylase
EDKNDPFM_00514 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EDKNDPFM_00515 8.8e-27 lanR K sequence-specific DNA binding
EDKNDPFM_00516 1.4e-33 V CAAX protease self-immunity
EDKNDPFM_00517 5e-67 V CAAX protease self-immunity
EDKNDPFM_00519 1.8e-111 S CAAX amino terminal protease family protein
EDKNDPFM_00520 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EDKNDPFM_00521 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EDKNDPFM_00522 4.1e-09 S Domain of unknown function (DUF4651)
EDKNDPFM_00523 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EDKNDPFM_00524 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EDKNDPFM_00525 1.8e-187 yeeE S Sulphur transport
EDKNDPFM_00526 6.4e-37 yeeD O sulfur carrier activity
EDKNDPFM_00527 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EDKNDPFM_00528 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EDKNDPFM_00530 1.3e-156 rrmA 2.1.1.187 Q methyltransferase
EDKNDPFM_00531 3.4e-64 S phosphatase activity
EDKNDPFM_00532 2.7e-48 S glycolate biosynthetic process
EDKNDPFM_00533 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EDKNDPFM_00534 1.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EDKNDPFM_00535 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EDKNDPFM_00536 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
EDKNDPFM_00537 1.6e-249 L Transposase
EDKNDPFM_00538 7.8e-28 L transposase activity
EDKNDPFM_00539 5.6e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
EDKNDPFM_00540 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EDKNDPFM_00541 2.5e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
EDKNDPFM_00542 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
EDKNDPFM_00543 0.0 uup S abc transporter atp-binding protein
EDKNDPFM_00544 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
EDKNDPFM_00545 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EDKNDPFM_00546 8.7e-150 cobQ S glutamine amidotransferase
EDKNDPFM_00547 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
EDKNDPFM_00548 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EDKNDPFM_00549 6e-169 ybbR S Protein conserved in bacteria
EDKNDPFM_00550 1.6e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EDKNDPFM_00551 1.7e-70 gtrA S GtrA-like protein
EDKNDPFM_00552 8.7e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
EDKNDPFM_00553 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EDKNDPFM_00554 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
EDKNDPFM_00555 1.1e-206 yurR 1.4.5.1 E oxidoreductase
EDKNDPFM_00556 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EDKNDPFM_00557 2.1e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EDKNDPFM_00558 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EDKNDPFM_00561 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
EDKNDPFM_00562 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
EDKNDPFM_00563 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EDKNDPFM_00564 5.3e-121 ylfI S tigr01906
EDKNDPFM_00565 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
EDKNDPFM_00566 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EDKNDPFM_00567 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EDKNDPFM_00568 1.3e-22 XK27_08085
EDKNDPFM_00569 5.2e-36 L transposase activity
EDKNDPFM_00570 1.8e-21 L Transposase
EDKNDPFM_00571 1.1e-53 L transposition
EDKNDPFM_00572 1.4e-86 L Integrase core domain protein
EDKNDPFM_00574 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EDKNDPFM_00575 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EDKNDPFM_00576 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EDKNDPFM_00577 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EDKNDPFM_00578 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EDKNDPFM_00579 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EDKNDPFM_00580 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EDKNDPFM_00581 1.9e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EDKNDPFM_00582 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EDKNDPFM_00583 4.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
EDKNDPFM_00584 1.6e-239 rodA D Belongs to the SEDS family
EDKNDPFM_00585 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EDKNDPFM_00586 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EDKNDPFM_00587 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EDKNDPFM_00588 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EDKNDPFM_00589 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
EDKNDPFM_00590 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EDKNDPFM_00591 6e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EDKNDPFM_00592 2.9e-125 dnaD
EDKNDPFM_00593 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EDKNDPFM_00596 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EDKNDPFM_00597 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
EDKNDPFM_00598 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EDKNDPFM_00599 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EDKNDPFM_00600 1.8e-72 argR K Regulates arginine biosynthesis genes
EDKNDPFM_00601 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
EDKNDPFM_00602 1e-148 DegV S DegV family
EDKNDPFM_00603 3.9e-143 ypmR E lipolytic protein G-D-S-L family
EDKNDPFM_00604 1.7e-83 ypmS S Protein conserved in bacteria
EDKNDPFM_00605 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EDKNDPFM_00607 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
EDKNDPFM_00608 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EDKNDPFM_00609 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EDKNDPFM_00610 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EDKNDPFM_00611 2.5e-43 ysdA L Membrane
EDKNDPFM_00612 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EDKNDPFM_00613 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EDKNDPFM_00614 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
EDKNDPFM_00615 0.0 dnaE 2.7.7.7 L DNA polymerase
EDKNDPFM_00616 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EDKNDPFM_00617 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EDKNDPFM_00619 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
EDKNDPFM_00620 3e-25 Q the current gene model (or a revised gene model) may contain a frame shift
EDKNDPFM_00621 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
EDKNDPFM_00623 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
EDKNDPFM_00624 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
EDKNDPFM_00625 4.4e-135 XK27_08845 S abc transporter atp-binding protein
EDKNDPFM_00626 3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EDKNDPFM_00627 1.6e-151 estA CE1 S Putative esterase
EDKNDPFM_00628 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
EDKNDPFM_00629 5.5e-14 XK27_08880
EDKNDPFM_00630 2.3e-75 fld C Flavodoxin
EDKNDPFM_00631 1.3e-282 clcA P Chloride transporter, ClC family
EDKNDPFM_00632 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
EDKNDPFM_00633 2.1e-219 XK27_05110 P chloride
EDKNDPFM_00634 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EDKNDPFM_00637 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
EDKNDPFM_00638 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EDKNDPFM_00639 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
EDKNDPFM_00640 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EDKNDPFM_00641 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EDKNDPFM_00642 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EDKNDPFM_00643 5.9e-26 G Domain of unknown function (DUF4832)
EDKNDPFM_00644 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EDKNDPFM_00646 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EDKNDPFM_00647 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
EDKNDPFM_00648 2.4e-124 endA F DNA RNA non-specific endonuclease
EDKNDPFM_00649 1.7e-111 tcyB_2 P ABC transporter (permease)
EDKNDPFM_00650 5.9e-118 gltJ P ABC transporter (Permease
EDKNDPFM_00651 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EDKNDPFM_00652 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDKNDPFM_00653 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDKNDPFM_00654 1.5e-247 vicK 2.7.13.3 T Histidine kinase
EDKNDPFM_00655 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
EDKNDPFM_00656 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
EDKNDPFM_00657 9.2e-147 yidA S hydrolases of the HAD superfamily
EDKNDPFM_00658 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
EDKNDPFM_00659 2.6e-67 ywiB S Domain of unknown function (DUF1934)
EDKNDPFM_00660 0.0 pacL 3.6.3.8 P cation transport ATPase
EDKNDPFM_00661 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EDKNDPFM_00662 4.3e-180 yjjH S Calcineurin-like phosphoesterase
EDKNDPFM_00663 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EDKNDPFM_00664 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EDKNDPFM_00665 2.5e-124 ftsE D cell division ATP-binding protein FtsE
EDKNDPFM_00666 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EDKNDPFM_00667 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
EDKNDPFM_00668 4e-175 yubA S permease
EDKNDPFM_00669 8.3e-224 G COG0457 FOG TPR repeat
EDKNDPFM_00670 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EDKNDPFM_00671 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EDKNDPFM_00672 2.9e-90 ebsA S Family of unknown function (DUF5322)
EDKNDPFM_00673 1.4e-22 M LysM domain
EDKNDPFM_00674 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EDKNDPFM_00675 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EDKNDPFM_00676 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EDKNDPFM_00677 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EDKNDPFM_00678 4.6e-82 L Transposase
EDKNDPFM_00679 2e-41 XK27_03610 K Gnat family
EDKNDPFM_00680 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EDKNDPFM_00681 2.4e-275 pepV 3.5.1.18 E Dipeptidase
EDKNDPFM_00682 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
EDKNDPFM_00683 4e-21 V Glucan-binding protein C
EDKNDPFM_00685 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EDKNDPFM_00686 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EDKNDPFM_00687 2.3e-66 S Protein of unknown function (DUF1697)
EDKNDPFM_00688 4.4e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EDKNDPFM_00689 4.9e-80 clcA_2 P chloride
EDKNDPFM_00690 6.3e-13 yfeJ 6.3.5.2 F glutamine amidotransferase
EDKNDPFM_00691 9.8e-96 yfeJ 6.3.5.2 F glutamine amidotransferase
EDKNDPFM_00692 3.4e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
EDKNDPFM_00693 5.9e-253 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
EDKNDPFM_00694 2.8e-134 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
EDKNDPFM_00695 2e-105 cps4C M biosynthesis protein
EDKNDPFM_00696 2.8e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
EDKNDPFM_00697 1.7e-249 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
EDKNDPFM_00698 9.7e-23 rgpAc GT4 M group 1 family protein
EDKNDPFM_00699 5.8e-28 tnp L DDE domain
EDKNDPFM_00700 2.2e-22 L Transposase
EDKNDPFM_00701 4.7e-140 L Integrase core domain
EDKNDPFM_00702 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
EDKNDPFM_00703 6.8e-69 L Transposase
EDKNDPFM_00704 7.8e-82 L Transposase
EDKNDPFM_00705 1.3e-23 L Transposase
EDKNDPFM_00706 6.4e-236 cps1C S Polysaccharide biosynthesis protein
EDKNDPFM_00707 5e-38 L transposase activity
EDKNDPFM_00708 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
EDKNDPFM_00709 7e-66 cpsF M Oligosaccharide biosynthesis protein Alg14 like
EDKNDPFM_00710 1.5e-41 pssE S Glycosyltransferase family 28 C-terminal domain
EDKNDPFM_00711 6.5e-72 M Glycosyltransferase sugar-binding region containing DXD motif
EDKNDPFM_00712 1.6e-16
EDKNDPFM_00713 9.4e-14 S Glycosyltransferase like family 2
EDKNDPFM_00714 9.7e-07 M Glycosyltransferase like family 2
EDKNDPFM_00715 6.3e-111 L Transposase
EDKNDPFM_00716 3e-113 L Transposase
EDKNDPFM_00717 6.7e-230 L Transposase
EDKNDPFM_00718 1.2e-21 L Transposase
EDKNDPFM_00719 4.9e-94 V VanZ like family
EDKNDPFM_00720 1.1e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EDKNDPFM_00721 2.4e-68 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
EDKNDPFM_00722 5.6e-101 G Belongs to the phosphoglycerate mutase family
EDKNDPFM_00723 1.3e-199 S hmm pf01594
EDKNDPFM_00724 1.8e-98 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDKNDPFM_00725 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
EDKNDPFM_00726 7.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EDKNDPFM_00727 4.9e-39 S granule-associated protein
EDKNDPFM_00728 7.7e-291 S unusual protein kinase
EDKNDPFM_00729 2.6e-15 estA E Lysophospholipase L1 and related esterases
EDKNDPFM_00730 3.9e-78 estA E GDSL-like protein
EDKNDPFM_00731 1.2e-157 rssA S Phospholipase, patatin family
EDKNDPFM_00732 1.1e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EDKNDPFM_00733 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EDKNDPFM_00734 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EDKNDPFM_00735 4.4e-66 S the current gene model (or a revised gene model) may contain a frame shift
EDKNDPFM_00736 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EDKNDPFM_00737 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EDKNDPFM_00738 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EDKNDPFM_00739 0.0 lpdA 1.8.1.4 C Dehydrogenase
EDKNDPFM_00740 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EDKNDPFM_00741 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EDKNDPFM_00742 8.5e-266 3.5.1.28 NU amidase activity
EDKNDPFM_00743 1.9e-37 3.5.1.28 NU amidase activity
EDKNDPFM_00744 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDKNDPFM_00745 3.9e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDKNDPFM_00746 1.1e-53 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDKNDPFM_00747 2e-139 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EDKNDPFM_00748 4e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EDKNDPFM_00749 2.5e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EDKNDPFM_00750 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
EDKNDPFM_00751 2.2e-177 fatB P ABC-type enterochelin transport system, periplasmic component
EDKNDPFM_00752 2.1e-152 ycdO P periplasmic lipoprotein involved in iron transport
EDKNDPFM_00753 1.5e-233 ycdB P peroxidase
EDKNDPFM_00754 3e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
EDKNDPFM_00755 1.7e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EDKNDPFM_00756 4.6e-25 tatA U protein secretion
EDKNDPFM_00757 2.4e-111 malF P ABC transporter (Permease
EDKNDPFM_00758 1.9e-93 malX G ABC transporter
EDKNDPFM_00759 4.2e-17 malX G ABC transporter
EDKNDPFM_00760 4.2e-27 malR K Transcriptional regulator
EDKNDPFM_00761 2.4e-63 malR K Transcriptional regulator
EDKNDPFM_00762 1.9e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
EDKNDPFM_00763 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EDKNDPFM_00764 3.7e-09
EDKNDPFM_00765 1.1e-17
EDKNDPFM_00766 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
EDKNDPFM_00767 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
EDKNDPFM_00768 0.0 pepN 3.4.11.2 E aminopeptidase
EDKNDPFM_00769 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
EDKNDPFM_00770 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EDKNDPFM_00771 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EDKNDPFM_00772 1.2e-155 pstA P phosphate transport system permease
EDKNDPFM_00773 1.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
EDKNDPFM_00774 3.3e-158 pstS P phosphate
EDKNDPFM_00775 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EDKNDPFM_00776 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EDKNDPFM_00777 1.9e-43 yktA S Belongs to the UPF0223 family
EDKNDPFM_00778 6.1e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EDKNDPFM_00779 2.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EDKNDPFM_00780 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EDKNDPFM_00781 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
EDKNDPFM_00782 3.6e-136 XK27_04775 S hemerythrin HHE cation binding domain
EDKNDPFM_00783 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
EDKNDPFM_00784 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EDKNDPFM_00785 9.3e-62 S haloacid dehalogenase-like hydrolase
EDKNDPFM_00786 1.8e-59 Q phosphatase activity
EDKNDPFM_00787 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
EDKNDPFM_00788 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EDKNDPFM_00789 1.8e-240 agcS E (Alanine) symporter
EDKNDPFM_00790 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EDKNDPFM_00791 7.6e-64 yfiF3 K sequence-specific DNA binding
EDKNDPFM_00792 3.7e-60 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
EDKNDPFM_00793 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
EDKNDPFM_00795 3.5e-68 yecS P ABC transporter (Permease
EDKNDPFM_00796 8.2e-132 yckB ET Belongs to the bacterial solute-binding protein 3 family
EDKNDPFM_00797 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
EDKNDPFM_00798 9.3e-267 dtpT E transporter
EDKNDPFM_00799 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EDKNDPFM_00800 2e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EDKNDPFM_00801 5.2e-74 csm6 S Psort location Cytoplasmic, score
EDKNDPFM_00802 2.1e-14 csm6 S Psort location Cytoplasmic, score
EDKNDPFM_00803 1e-193 csm5 L CRISPR-associated RAMP protein, Csm5 family
EDKNDPFM_00804 1.4e-164 csm4 L CRISPR-associated RAMP protein, Csm4 family
EDKNDPFM_00805 1.1e-116 csm3 L RAMP superfamily
EDKNDPFM_00806 5.6e-62 csm2 L Pfam:DUF310
EDKNDPFM_00807 0.0 csm1 S CRISPR-associated protein Csm1 family
EDKNDPFM_00808 1.3e-131 cas6 S CRISPR-associated endoribonuclease Cas6
EDKNDPFM_00809 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDKNDPFM_00810 1.8e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDKNDPFM_00811 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EDKNDPFM_00812 2.4e-147 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EDKNDPFM_00813 3.2e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
EDKNDPFM_00814 2.1e-98 S TraX protein
EDKNDPFM_00815 6.4e-24 L Transposase
EDKNDPFM_00817 1.1e-12
EDKNDPFM_00818 2e-29
EDKNDPFM_00820 1.4e-189
EDKNDPFM_00821 2.1e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EDKNDPFM_00823 6.3e-12 dinF V Mate efflux family protein
EDKNDPFM_00824 8.8e-55 dinF V Mate efflux family protein
EDKNDPFM_00825 1.2e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
EDKNDPFM_00826 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
EDKNDPFM_00827 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
EDKNDPFM_00828 2.6e-143 2.4.2.3 F Phosphorylase superfamily
EDKNDPFM_00831 3.8e-78 S Alpha/beta hydrolase of unknown function (DUF915)
EDKNDPFM_00832 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
EDKNDPFM_00833 6e-08 S Hydrolases of the alpha beta superfamily
EDKNDPFM_00834 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
EDKNDPFM_00835 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EDKNDPFM_00836 1.8e-159 czcD P cation diffusion facilitator family transporter
EDKNDPFM_00837 9e-98 K Transcriptional regulator, TetR family
EDKNDPFM_00838 1.6e-10
EDKNDPFM_00839 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EDKNDPFM_00840 3e-14 V ABC transporter (Permease
EDKNDPFM_00841 4.1e-88 V ABC transporter (Permease
EDKNDPFM_00842 5.1e-41 L Transposase
EDKNDPFM_00843 9.6e-13
EDKNDPFM_00844 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
EDKNDPFM_00845 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EDKNDPFM_00846 8.6e-61 EGP Major facilitator Superfamily
EDKNDPFM_00847 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
EDKNDPFM_00848 7.2e-212 pqqE C radical SAM domain protein
EDKNDPFM_00851 6.7e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EDKNDPFM_00852 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EDKNDPFM_00853 3.9e-19 IQ Acetoin reductase
EDKNDPFM_00854 2.2e-49 IQ Acetoin reductase
EDKNDPFM_00855 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EDKNDPFM_00856 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EDKNDPFM_00857 7.5e-21 XK27_05470 E Methionine synthase
EDKNDPFM_00858 4.1e-68 XK27_05470 E Methionine synthase
EDKNDPFM_00859 1.2e-74 XK27_05470 E Methionine synthase
EDKNDPFM_00860 2.1e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EDKNDPFM_00861 7.6e-250 T PhoQ Sensor
EDKNDPFM_00862 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDKNDPFM_00863 3.6e-154 S TraX protein
EDKNDPFM_00864 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EDKNDPFM_00865 8.3e-159 dprA LU DNA protecting protein DprA
EDKNDPFM_00866 1.6e-166 GK ROK family
EDKNDPFM_00867 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EDKNDPFM_00868 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EDKNDPFM_00869 8.1e-128 K DNA-binding helix-turn-helix protein
EDKNDPFM_00870 3e-90 niaR S small molecule binding protein (contains 3H domain)
EDKNDPFM_00871 3.1e-87 niaX
EDKNDPFM_00872 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EDKNDPFM_00873 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EDKNDPFM_00874 2e-126 gntR1 K transcriptional
EDKNDPFM_00875 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EDKNDPFM_00876 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
EDKNDPFM_00877 0.0 res_1 3.1.21.5 S Type III restriction
EDKNDPFM_00878 1.1e-20
EDKNDPFM_00880 7.4e-110 adhP 1.1.1.1 C alcohol dehydrogenase
EDKNDPFM_00881 2.3e-62 adhP 1.1.1.1 C alcohol dehydrogenase
EDKNDPFM_00882 2.1e-07
EDKNDPFM_00883 7.3e-110 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDKNDPFM_00884 2.4e-72 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EDKNDPFM_00885 2.1e-157 aatB ET ABC transporter substrate-binding protein
EDKNDPFM_00886 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDKNDPFM_00887 4e-105 artQ P ABC transporter (Permease
EDKNDPFM_00888 7.3e-58 phnA P Alkylphosphonate utilization operon protein PhnA
EDKNDPFM_00889 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EDKNDPFM_00890 4.5e-166 cpsY K Transcriptional regulator
EDKNDPFM_00891 1.6e-19 L transposase activity
EDKNDPFM_00892 1.6e-118 mur1 NU muramidase
EDKNDPFM_00893 1e-171 yeiH S Membrane
EDKNDPFM_00894 5.8e-09
EDKNDPFM_00895 5.6e-294 adcA P Belongs to the bacterial solute-binding protein 9 family
EDKNDPFM_00896 2.6e-86 XK27_10720 D peptidase activity
EDKNDPFM_00897 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
EDKNDPFM_00898 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
EDKNDPFM_00899 2.3e-151 glcU U Glucose uptake
EDKNDPFM_00900 2.3e-113 hsdM 2.1.1.72 V type I restriction-modification system
EDKNDPFM_00901 8.8e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
EDKNDPFM_00902 6.4e-69 L Transposase
EDKNDPFM_00903 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
EDKNDPFM_00904 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EDKNDPFM_00905 1.9e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EDKNDPFM_00906 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EDKNDPFM_00907 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EDKNDPFM_00908 7.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EDKNDPFM_00909 2.2e-27 XK27_08585 S Psort location CytoplasmicMembrane, score
EDKNDPFM_00910 1.2e-23 XK27_08585 S Psort location CytoplasmicMembrane, score
EDKNDPFM_00911 2.1e-115 fnt P Formate nitrite transporter
EDKNDPFM_00912 4.7e-213 XK27_09615 C reductase
EDKNDPFM_00913 6.2e-76 XK27_09620 S reductase
EDKNDPFM_00914 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
EDKNDPFM_00915 5.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EDKNDPFM_00916 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EDKNDPFM_00917 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
EDKNDPFM_00918 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
EDKNDPFM_00919 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
EDKNDPFM_00920 3.5e-50 S Protein of unknown function (DUF3397)
EDKNDPFM_00921 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EDKNDPFM_00922 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EDKNDPFM_00923 4.2e-74 amiA E transmembrane transport
EDKNDPFM_00924 2.2e-79 amiA E transmembrane transport
EDKNDPFM_00925 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EDKNDPFM_00926 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EDKNDPFM_00927 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
EDKNDPFM_00928 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EDKNDPFM_00929 2.8e-124 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EDKNDPFM_00930 3.5e-88 L Transposase
EDKNDPFM_00931 0.0 copB 3.6.3.4 P P-type ATPase
EDKNDPFM_00932 9.4e-43 K Cold-Shock Protein
EDKNDPFM_00933 7.4e-32 cspD K Cold shock protein domain
EDKNDPFM_00934 6.7e-40 pepD E dipeptidase activity
EDKNDPFM_00935 1.5e-138 pepD E Dipeptidase
EDKNDPFM_00936 2.5e-161 whiA K May be required for sporulation
EDKNDPFM_00937 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EDKNDPFM_00938 2e-163 rapZ S Displays ATPase and GTPase activities
EDKNDPFM_00939 1.2e-135 yejC S cyclic nucleotide-binding protein
EDKNDPFM_00940 2.2e-19 D nuclear chromosome segregation
EDKNDPFM_00941 1.9e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
EDKNDPFM_00942 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EDKNDPFM_00943 5.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
EDKNDPFM_00944 9.8e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EDKNDPFM_00945 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
EDKNDPFM_00946 2.7e-31 L Transposase
EDKNDPFM_00947 6.8e-54 L Transposase
EDKNDPFM_00948 2.5e-15
EDKNDPFM_00949 4.2e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EDKNDPFM_00950 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EDKNDPFM_00951 3.1e-81 ypmB S Protein conserved in bacteria
EDKNDPFM_00952 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EDKNDPFM_00953 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EDKNDPFM_00954 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
EDKNDPFM_00955 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
EDKNDPFM_00956 2.7e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EDKNDPFM_00957 1.5e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EDKNDPFM_00958 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EDKNDPFM_00959 1.5e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EDKNDPFM_00960 5.5e-29 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EDKNDPFM_00961 7.5e-101 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
EDKNDPFM_00962 1.3e-24 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
EDKNDPFM_00963 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
EDKNDPFM_00964 2.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
EDKNDPFM_00965 2.1e-30 rpsT J rRNA binding
EDKNDPFM_00966 6.7e-122 L Helix-turn-helix domain
EDKNDPFM_00967 1.2e-165 L integrase core domain
EDKNDPFM_00968 8.3e-78 T PhoQ Sensor
EDKNDPFM_00969 1.7e-43 T PhoQ Sensor
EDKNDPFM_00970 2.8e-40 T PhoQ Sensor
EDKNDPFM_00971 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDKNDPFM_00972 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EDKNDPFM_00973 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
EDKNDPFM_00974 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EDKNDPFM_00975 1.4e-93 panT S ECF transporter, substrate-specific component
EDKNDPFM_00976 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EDKNDPFM_00977 7.3e-166 metF 1.5.1.20 E reductase
EDKNDPFM_00978 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EDKNDPFM_00980 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
EDKNDPFM_00981 0.0 3.6.3.8 P cation transport ATPase
EDKNDPFM_00982 7.7e-19 L transposase activity
EDKNDPFM_00983 6.5e-54 L transposition
EDKNDPFM_00984 9.6e-32 L transposition
EDKNDPFM_00985 9.8e-32 L Integrase core domain protein
EDKNDPFM_00986 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EDKNDPFM_00987 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDKNDPFM_00988 4.6e-238 dltB M Membrane protein involved in D-alanine export
EDKNDPFM_00989 1.6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDKNDPFM_00990 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
EDKNDPFM_00991 0.0 XK27_10035 V abc transporter atp-binding protein
EDKNDPFM_00992 0.0 yfiB1 V abc transporter atp-binding protein
EDKNDPFM_00993 8e-100 pvaA M lytic transglycosylase activity
EDKNDPFM_00994 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
EDKNDPFM_00995 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EDKNDPFM_00996 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EDKNDPFM_00997 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EDKNDPFM_00998 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EDKNDPFM_00999 4.5e-111 tdk 2.7.1.21 F thymidine kinase
EDKNDPFM_01000 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EDKNDPFM_01001 1.5e-154 gst O Glutathione S-transferase
EDKNDPFM_01002 3e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
EDKNDPFM_01003 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EDKNDPFM_01004 2e-45 rpmE2 J 50S ribosomal protein L31
EDKNDPFM_01005 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
EDKNDPFM_01006 8.4e-10
EDKNDPFM_01007 5.5e-30
EDKNDPFM_01008 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EDKNDPFM_01009 6.7e-135 divIVA D Cell division protein DivIVA
EDKNDPFM_01010 1.2e-143 ylmH T S4 RNA-binding domain
EDKNDPFM_01011 1.2e-34 yggT D integral membrane protein
EDKNDPFM_01012 2e-95 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EDKNDPFM_01013 7.8e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EDKNDPFM_01014 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EDKNDPFM_01015 4.4e-250 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EDKNDPFM_01016 8.2e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EDKNDPFM_01017 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EDKNDPFM_01018 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EDKNDPFM_01020 0.0 typA T GTP-binding protein TypA
EDKNDPFM_01021 2.2e-179 glk 2.7.1.2 G Glucokinase
EDKNDPFM_01022 8.4e-28 yqgQ S protein conserved in bacteria
EDKNDPFM_01023 1.1e-80 perR P Belongs to the Fur family
EDKNDPFM_01024 3.5e-91 dps P Belongs to the Dps family
EDKNDPFM_01025 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
EDKNDPFM_01026 1.4e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
EDKNDPFM_01027 3e-50 L Transposase
EDKNDPFM_01028 1.9e-23 L Transposase
EDKNDPFM_01029 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
EDKNDPFM_01030 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
EDKNDPFM_01031 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EDKNDPFM_01032 6.2e-56 S Domain of unknown function (DUF4430)
EDKNDPFM_01033 1.8e-73 S Psort location CytoplasmicMembrane, score
EDKNDPFM_01034 1.8e-135 htpX O Belongs to the peptidase M48B family
EDKNDPFM_01035 1.5e-92 lemA S LemA family
EDKNDPFM_01036 4.4e-148 spd F DNA RNA non-specific endonuclease
EDKNDPFM_01037 6.9e-90 S double-stranded DNA endodeoxyribonuclease activity
EDKNDPFM_01038 3.4e-49 S PD-(D/E)XK nuclease family transposase
EDKNDPFM_01039 1.4e-36 prrC S AAA domain
EDKNDPFM_01040 5e-27 prrC S AAA domain
EDKNDPFM_01041 3.1e-53 prrC S AAA domain
EDKNDPFM_01042 2.5e-11 prrC S AAA domain
EDKNDPFM_01043 2.3e-85 3.1.21.3 V type I restriction modification DNA specificity domain
EDKNDPFM_01044 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
EDKNDPFM_01045 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
EDKNDPFM_01046 1.4e-44 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EDKNDPFM_01047 8.3e-76 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EDKNDPFM_01048 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
EDKNDPFM_01049 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
EDKNDPFM_01050 1.4e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EDKNDPFM_01051 2.1e-27 P Hemerythrin HHE cation binding domain protein
EDKNDPFM_01052 5.9e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
EDKNDPFM_01053 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EDKNDPFM_01054 1.5e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
EDKNDPFM_01055 5.4e-172 S hydrolase
EDKNDPFM_01056 3.1e-20
EDKNDPFM_01057 2.4e-58 M LysM domain
EDKNDPFM_01058 1.9e-15 M LysM domain
EDKNDPFM_01059 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EDKNDPFM_01060 1.2e-33 S SIR2-like domain
EDKNDPFM_01061 5.2e-29 S SIR2-like domain
EDKNDPFM_01062 4.1e-225 mutH L DNA mismatch repair enzyme MutH
EDKNDPFM_01063 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
EDKNDPFM_01064 4.8e-11
EDKNDPFM_01065 5.1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
EDKNDPFM_01066 1.1e-33 XK27_12190 S protein conserved in bacteria
EDKNDPFM_01068 9.3e-87 bioY S biotin synthase
EDKNDPFM_01069 8.1e-46 S CHY zinc finger
EDKNDPFM_01070 3.4e-252 yegQ O Peptidase U32
EDKNDPFM_01071 2e-177 yegQ O Peptidase U32
EDKNDPFM_01073 5.5e-69 ytxH S General stress protein
EDKNDPFM_01075 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EDKNDPFM_01076 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EDKNDPFM_01077 2.2e-41 pspC KT PspC domain
EDKNDPFM_01078 0.0 yhgF K Transcriptional accessory protein
EDKNDPFM_01080 7.1e-156 XK27_03015 S permease
EDKNDPFM_01081 7.8e-146 ycgQ S TIGR03943 family
EDKNDPFM_01082 2.6e-194 S CRISPR-associated protein Csn2 subfamily St
EDKNDPFM_01083 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDKNDPFM_01084 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EDKNDPFM_01085 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EDKNDPFM_01086 1.4e-94
EDKNDPFM_01087 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
EDKNDPFM_01088 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
EDKNDPFM_01089 1e-31 K Cro/C1-type HTH DNA-binding domain
EDKNDPFM_01090 3.2e-46
EDKNDPFM_01091 8.9e-20
EDKNDPFM_01092 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EDKNDPFM_01093 4.5e-97 mip S hydroperoxide reductase activity
EDKNDPFM_01094 2.4e-203 I acyl-CoA dehydrogenase
EDKNDPFM_01095 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
EDKNDPFM_01096 6.4e-252 msrR K Transcriptional regulator
EDKNDPFM_01097 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
EDKNDPFM_01098 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EDKNDPFM_01099 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EDKNDPFM_01100 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EDKNDPFM_01101 3.2e-53 yheA S Belongs to the UPF0342 family
EDKNDPFM_01102 8.3e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EDKNDPFM_01103 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EDKNDPFM_01104 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EDKNDPFM_01105 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EDKNDPFM_01106 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EDKNDPFM_01107 2e-219 ywbD 2.1.1.191 J Methyltransferase
EDKNDPFM_01108 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EDKNDPFM_01109 2e-25 WQ51_00785
EDKNDPFM_01110 2.8e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EDKNDPFM_01111 1e-78 yueI S Protein of unknown function (DUF1694)
EDKNDPFM_01112 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EDKNDPFM_01113 6.6e-101 yyaQ V Protein conserved in bacteria
EDKNDPFM_01114 2.8e-28 yyaQ S YjbR
EDKNDPFM_01115 4.4e-183 ccpA K Catabolite control protein A
EDKNDPFM_01116 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
EDKNDPFM_01117 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
EDKNDPFM_01118 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EDKNDPFM_01119 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EDKNDPFM_01120 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EDKNDPFM_01121 2e-33 secG U Preprotein translocase subunit SecG
EDKNDPFM_01122 3.6e-219 mdtG EGP Major facilitator Superfamily
EDKNDPFM_01123 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EDKNDPFM_01124 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EDKNDPFM_01125 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EDKNDPFM_01126 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EDKNDPFM_01127 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EDKNDPFM_01128 6.8e-53 licT K transcriptional antiterminator
EDKNDPFM_01129 5.8e-64 licT K transcriptional antiterminator
EDKNDPFM_01130 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EDKNDPFM_01131 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
EDKNDPFM_01132 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EDKNDPFM_01133 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EDKNDPFM_01134 7.5e-23 I Alpha/beta hydrolase family
EDKNDPFM_01135 1.5e-35 yugF I carboxylic ester hydrolase activity
EDKNDPFM_01136 2.2e-45 K sequence-specific DNA binding
EDKNDPFM_01137 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EDKNDPFM_01138 1.5e-07
EDKNDPFM_01139 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EDKNDPFM_01140 1.1e-78 feoA P FeoA domain protein
EDKNDPFM_01141 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
EDKNDPFM_01142 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
EDKNDPFM_01143 1.3e-34 ykuJ S protein conserved in bacteria
EDKNDPFM_01144 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EDKNDPFM_01145 0.0 clpE O Belongs to the ClpA ClpB family
EDKNDPFM_01146 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EDKNDPFM_01147 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
EDKNDPFM_01148 9.7e-66 S oxidoreductase
EDKNDPFM_01149 9.3e-59 S oxidoreductase
EDKNDPFM_01150 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
EDKNDPFM_01151 6.1e-70 M Pfam SNARE associated Golgi protein
EDKNDPFM_01152 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
EDKNDPFM_01155 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
EDKNDPFM_01158 4.8e-16 S Protein of unknown function (DUF2969)
EDKNDPFM_01159 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
EDKNDPFM_01160 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EDKNDPFM_01161 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EDKNDPFM_01162 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EDKNDPFM_01163 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
EDKNDPFM_01164 1.4e-29 S Domain of unknown function (DUF1912)
EDKNDPFM_01165 4.5e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
EDKNDPFM_01166 2.2e-249 mmuP E amino acid
EDKNDPFM_01167 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
EDKNDPFM_01168 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EDKNDPFM_01169 9.7e-22
EDKNDPFM_01170 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EDKNDPFM_01171 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EDKNDPFM_01172 1.7e-218 mvaS 2.3.3.10 I synthase
EDKNDPFM_01173 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EDKNDPFM_01174 1e-25 K hmm pf08876
EDKNDPFM_01175 1.5e-118 yqfA K protein, Hemolysin III
EDKNDPFM_01176 1.2e-22 S Protein of unknown function (DUF3114)
EDKNDPFM_01177 9.8e-163 S Protein of unknown function (DUF3114)
EDKNDPFM_01178 9.9e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EDKNDPFM_01179 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EDKNDPFM_01180 4.9e-21 XK27_13030
EDKNDPFM_01181 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EDKNDPFM_01182 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
EDKNDPFM_01183 1.1e-11 U protein secretion
EDKNDPFM_01184 2.1e-50 U protein secretion
EDKNDPFM_01185 3.5e-07 U protein secretion
EDKNDPFM_01187 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EDKNDPFM_01188 2.5e-21
EDKNDPFM_01189 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
EDKNDPFM_01190 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EDKNDPFM_01191 3.4e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EDKNDPFM_01192 5e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
EDKNDPFM_01193 1.3e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EDKNDPFM_01194 6.9e-140 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EDKNDPFM_01195 4.6e-105 GBS0088 J protein conserved in bacteria
EDKNDPFM_01196 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EDKNDPFM_01197 5.9e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EDKNDPFM_01198 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
EDKNDPFM_01199 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EDKNDPFM_01200 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EDKNDPFM_01201 9.6e-113 S VIT family
EDKNDPFM_01202 1.8e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
EDKNDPFM_01203 1.9e-22
EDKNDPFM_01204 8e-28 XK27_00085 K Transcriptional
EDKNDPFM_01205 6.9e-197 yceA S Belongs to the UPF0176 family
EDKNDPFM_01206 5.4e-122 sagI S ABC-2 type transporter
EDKNDPFM_01207 2.8e-168 V ABC transporter
EDKNDPFM_01208 2.5e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EDKNDPFM_01209 2.5e-132 rr02 KT response regulator
EDKNDPFM_01210 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
EDKNDPFM_01211 2.6e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EDKNDPFM_01212 6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EDKNDPFM_01213 0.0 lmrA V abc transporter atp-binding protein
EDKNDPFM_01214 0.0 mdlB V abc transporter atp-binding protein
EDKNDPFM_01216 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EDKNDPFM_01217 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EDKNDPFM_01218 7.2e-24 ytrF V efflux transmembrane transporter activity
EDKNDPFM_01219 4.6e-43 V efflux transmembrane transporter activity
EDKNDPFM_01220 1.7e-59 V permease protein
EDKNDPFM_01221 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EDKNDPFM_01222 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EDKNDPFM_01223 5.1e-131 2.1.1.223 S Putative SAM-dependent methyltransferase
EDKNDPFM_01224 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
EDKNDPFM_01225 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
EDKNDPFM_01226 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EDKNDPFM_01227 4.9e-227 pyrP F uracil Permease
EDKNDPFM_01228 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EDKNDPFM_01229 1e-156 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EDKNDPFM_01230 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EDKNDPFM_01231 1.4e-167 fhuR K transcriptional regulator (lysR family)
EDKNDPFM_01236 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EDKNDPFM_01237 9.7e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
EDKNDPFM_01238 2.5e-119 pts33BCA G pts system
EDKNDPFM_01239 1.7e-70 pts33BCA G pts system
EDKNDPFM_01240 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
EDKNDPFM_01241 1.8e-254 cycA E permease
EDKNDPFM_01242 4.5e-39 ynzC S UPF0291 protein
EDKNDPFM_01243 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EDKNDPFM_01244 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EDKNDPFM_01245 6.1e-63 S membrane
EDKNDPFM_01246 1.5e-59
EDKNDPFM_01247 7.5e-26
EDKNDPFM_01248 1.8e-53
EDKNDPFM_01249 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EDKNDPFM_01250 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
EDKNDPFM_01251 2.2e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
EDKNDPFM_01252 3.2e-105 mur1 NU mannosyl-glycoprotein
EDKNDPFM_01253 6.6e-54 glnB K Belongs to the P(II) protein family
EDKNDPFM_01254 5.8e-233 amt P Ammonium Transporter
EDKNDPFM_01255 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EDKNDPFM_01256 9.5e-55 yabA L Involved in initiation control of chromosome replication
EDKNDPFM_01257 1.2e-135 yaaT S stage 0 sporulation protein
EDKNDPFM_01258 6.4e-162 holB 2.7.7.7 L dna polymerase iii
EDKNDPFM_01259 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EDKNDPFM_01260 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EDKNDPFM_01261 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EDKNDPFM_01262 2.8e-230 ftsW D Belongs to the SEDS family
EDKNDPFM_01263 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EDKNDPFM_01264 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EDKNDPFM_01265 9.6e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EDKNDPFM_01266 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EDKNDPFM_01267 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EDKNDPFM_01268 3.3e-78 atpF C ATP synthase F(0) sector subunit b
EDKNDPFM_01269 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
EDKNDPFM_01270 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EDKNDPFM_01271 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EDKNDPFM_01272 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EDKNDPFM_01273 1.1e-89 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EDKNDPFM_01274 8.9e-14 coiA 3.6.4.12 S Competence protein
EDKNDPFM_01275 2.2e-15 T peptidase
EDKNDPFM_01276 3e-151 rarD S Transporter
EDKNDPFM_01277 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EDKNDPFM_01278 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EDKNDPFM_01279 7.9e-128 yxkH G deacetylase
EDKNDPFM_01280 1.2e-208 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EDKNDPFM_01281 1.3e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EDKNDPFM_01282 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EDKNDPFM_01283 1.7e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EDKNDPFM_01284 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
EDKNDPFM_01285 2.6e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EDKNDPFM_01286 6.4e-52 3.4.17.14, 3.5.1.28 NU amidase activity
EDKNDPFM_01287 1.5e-23 3.4.17.14, 3.5.1.28 NU amidase activity
EDKNDPFM_01288 2.7e-14 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
EDKNDPFM_01289 3e-63 3.4.17.14, 3.5.1.28 NU amidase activity
EDKNDPFM_01290 6.2e-84 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EDKNDPFM_01291 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EDKNDPFM_01292 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EDKNDPFM_01293 1.1e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
EDKNDPFM_01294 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
EDKNDPFM_01295 0.0 pepF E oligoendopeptidase F
EDKNDPFM_01296 1.4e-186 coiA 3.6.4.12 S Competence protein
EDKNDPFM_01297 1.8e-164 K transcriptional regulator (lysR family)
EDKNDPFM_01298 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EDKNDPFM_01299 1.1e-156 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EDKNDPFM_01300 8.8e-48 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EDKNDPFM_01301 8.4e-205 nodC 2.4.1.212 GT2 M Chitin synthase
EDKNDPFM_01305 1e-190 phoH T phosphate starvation-inducible protein PhoH
EDKNDPFM_01306 2.2e-118 sip M LysM domain protein
EDKNDPFM_01307 7.4e-35 yozE S Belongs to the UPF0346 family
EDKNDPFM_01308 5.3e-161 cvfB S Protein conserved in bacteria
EDKNDPFM_01309 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EDKNDPFM_01310 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EDKNDPFM_01311 4.5e-77 sptS 2.7.13.3 T Histidine kinase
EDKNDPFM_01312 7.1e-37 K Acetyltransferase (GNAT) family
EDKNDPFM_01313 0.0 lmrA2 V abc transporter atp-binding protein
EDKNDPFM_01314 0.0 lmrA1 V abc transporter atp-binding protein
EDKNDPFM_01315 1.9e-77 K DNA-binding transcription factor activity
EDKNDPFM_01316 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EDKNDPFM_01317 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
EDKNDPFM_01318 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
EDKNDPFM_01319 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
EDKNDPFM_01320 1.6e-24 U response to pH
EDKNDPFM_01321 0.0 yfmR S abc transporter atp-binding protein
EDKNDPFM_01322 1.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EDKNDPFM_01323 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EDKNDPFM_01324 3.6e-74 XK27_08360 S EDD domain protein, DegV family
EDKNDPFM_01325 1.9e-60 XK27_08360 S EDD domain protein, DegV family
EDKNDPFM_01326 2.3e-60 WQ51_03320 S cog cog4835
EDKNDPFM_01327 3e-122 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EDKNDPFM_01328 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EDKNDPFM_01329 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
EDKNDPFM_01330 6.4e-29 2.3.1.128 K acetyltransferase
EDKNDPFM_01331 4.9e-39 2.3.1.128 K acetyltransferase
EDKNDPFM_01332 3e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EDKNDPFM_01333 5.5e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EDKNDPFM_01334 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EDKNDPFM_01335 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
EDKNDPFM_01337 3.4e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EDKNDPFM_01338 3.2e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EDKNDPFM_01339 2.7e-102 fruA 2.7.1.202 G phosphotransferase system
EDKNDPFM_01340 2.3e-25 fruA 2.7.1.202 G phosphotransferase system
EDKNDPFM_01341 7.8e-22 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
EDKNDPFM_01342 1.6e-78 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
EDKNDPFM_01343 4.6e-163 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EDKNDPFM_01344 2.1e-113 fruR K transcriptional
EDKNDPFM_01345 1.8e-84 L Transposase
EDKNDPFM_01346 2.3e-205 rny D Endoribonuclease that initiates mRNA decay
EDKNDPFM_01347 6.6e-38 L transposase activity
EDKNDPFM_01348 1.5e-07 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EDKNDPFM_01349 5.5e-184 jag S RNA-binding protein
EDKNDPFM_01350 1e-13 rpmH J Ribosomal protein L34
EDKNDPFM_01351 5e-84 L Transposase
EDKNDPFM_01352 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EDKNDPFM_01354 1.1e-16 L COG2801 Transposase and inactivated derivatives
EDKNDPFM_01355 3.2e-113 K sequence-specific DNA binding
EDKNDPFM_01356 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
EDKNDPFM_01357 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
EDKNDPFM_01358 5.1e-113 V (ABC) transporter
EDKNDPFM_01359 7.3e-55 V (ABC) transporter
EDKNDPFM_01360 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
EDKNDPFM_01361 8e-277 S Protein of unknown function (DUF3114)
EDKNDPFM_01363 3.4e-35 tnp L Transposase
EDKNDPFM_01364 1.3e-07 L Transposase and inactivated derivatives, TnpA family
EDKNDPFM_01365 4.4e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
EDKNDPFM_01366 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
EDKNDPFM_01367 1.1e-65 tnp L Transposase
EDKNDPFM_01368 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EDKNDPFM_01369 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EDKNDPFM_01370 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EDKNDPFM_01371 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EDKNDPFM_01372 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EDKNDPFM_01373 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EDKNDPFM_01374 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EDKNDPFM_01375 1.6e-126 IQ reductase
EDKNDPFM_01376 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EDKNDPFM_01377 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
EDKNDPFM_01378 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EDKNDPFM_01379 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EDKNDPFM_01380 4e-72 marR K Transcriptional regulator, MarR family
EDKNDPFM_01381 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
EDKNDPFM_01382 1.9e-115 S Haloacid dehalogenase-like hydrolase
EDKNDPFM_01383 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
EDKNDPFM_01384 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
EDKNDPFM_01385 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EDKNDPFM_01386 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
EDKNDPFM_01387 7.8e-102 ygaC J Belongs to the UPF0374 family
EDKNDPFM_01388 6.4e-108 S Domain of unknown function (DUF1803)
EDKNDPFM_01389 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
EDKNDPFM_01396 2.3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EDKNDPFM_01397 1.7e-122 comFC S Competence protein
EDKNDPFM_01398 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EDKNDPFM_01399 1.1e-110 yvyE 3.4.13.9 S YigZ family
EDKNDPFM_01400 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EDKNDPFM_01401 8.9e-41 acuB S IMP dehydrogenase activity
EDKNDPFM_01402 6.8e-69 acuB S IMP dehydrogenase activity
EDKNDPFM_01403 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
EDKNDPFM_01404 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
EDKNDPFM_01405 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
EDKNDPFM_01406 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
EDKNDPFM_01407 1.8e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
EDKNDPFM_01408 7.1e-46 ylbG S UPF0298 protein
EDKNDPFM_01409 1.2e-74 ylbF S Belongs to the UPF0342 family
EDKNDPFM_01410 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EDKNDPFM_01411 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EDKNDPFM_01414 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EDKNDPFM_01415 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
EDKNDPFM_01416 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
EDKNDPFM_01417 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
EDKNDPFM_01418 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EDKNDPFM_01419 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
EDKNDPFM_01420 8.7e-41 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
EDKNDPFM_01421 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
EDKNDPFM_01422 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
EDKNDPFM_01423 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EDKNDPFM_01424 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EDKNDPFM_01425 1.4e-41 ylxQ J ribosomal protein
EDKNDPFM_01426 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
EDKNDPFM_01427 3.1e-212 nusA K Participates in both transcription termination and antitermination
EDKNDPFM_01428 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
EDKNDPFM_01429 2.8e-219 brpA K Transcriptional
EDKNDPFM_01430 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
EDKNDPFM_01431 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
EDKNDPFM_01432 1.9e-248 pbuO S permease
EDKNDPFM_01433 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
EDKNDPFM_01434 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
EDKNDPFM_01435 1.1e-181 manL 2.7.1.191 G pts system
EDKNDPFM_01436 2.3e-116 manM G pts system
EDKNDPFM_01437 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
EDKNDPFM_01438 4.2e-62 manO S protein conserved in bacteria
EDKNDPFM_01439 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EDKNDPFM_01440 9.4e-42 L Transposase
EDKNDPFM_01441 3e-27 L Integrase core domain protein
EDKNDPFM_01442 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
EDKNDPFM_01443 1.2e-34
EDKNDPFM_01445 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EDKNDPFM_01446 4.4e-166 dnaI L Primosomal protein DnaI
EDKNDPFM_01447 6.5e-218 dnaB L Replication initiation and membrane attachment
EDKNDPFM_01448 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EDKNDPFM_01449 2.8e-282 T PhoQ Sensor
EDKNDPFM_01450 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EDKNDPFM_01451 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
EDKNDPFM_01452 1.2e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
EDKNDPFM_01453 2.7e-244 P COG0168 Trk-type K transport systems, membrane components
EDKNDPFM_01454 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
EDKNDPFM_01455 6.9e-11 ulaG S L-ascorbate 6-phosphate lactonase
EDKNDPFM_01456 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EDKNDPFM_01457 4.7e-146 cbiQ P cobalt transport
EDKNDPFM_01458 0.0 ykoD P abc transporter atp-binding protein
EDKNDPFM_01459 9.4e-95 S UPF0397 protein
EDKNDPFM_01460 4.7e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
EDKNDPFM_01461 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EDKNDPFM_01462 8.8e-98 metI P ABC transporter (Permease
EDKNDPFM_01463 7.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EDKNDPFM_01464 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
EDKNDPFM_01465 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
EDKNDPFM_01466 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
EDKNDPFM_01467 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
EDKNDPFM_01468 4e-153 ET amino acid transport
EDKNDPFM_01469 3.8e-205 EGP Transmembrane secretion effector
EDKNDPFM_01470 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
EDKNDPFM_01471 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EDKNDPFM_01472 5.3e-153 ET amino acid transport
EDKNDPFM_01473 1.6e-131 cbiO P ABC transporter
EDKNDPFM_01474 1.1e-136 P cobalt transport protein
EDKNDPFM_01475 4.3e-175 cbiM P PDGLE domain
EDKNDPFM_01476 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EDKNDPFM_01477 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EDKNDPFM_01478 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EDKNDPFM_01479 6.6e-78 ureE O enzyme active site formation
EDKNDPFM_01480 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EDKNDPFM_01481 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EDKNDPFM_01482 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EDKNDPFM_01483 6.8e-95 ureI S AmiS/UreI family transporter
EDKNDPFM_01484 9.2e-132 S Domain of unknown function (DUF4173)
EDKNDPFM_01485 6.7e-36 S Domain of unknown function (DUF4173)
EDKNDPFM_01486 3.7e-51 yhaI L Membrane
EDKNDPFM_01487 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDKNDPFM_01488 1.8e-27 comA V protein secretion by the type I secretion system
EDKNDPFM_01489 1.1e-34 V protein secretion by the type I secretion system
EDKNDPFM_01490 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDKNDPFM_01491 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDKNDPFM_01492 1.2e-32 V protein secretion by the type I secretion system
EDKNDPFM_01493 5.6e-161 K sequence-specific DNA binding
EDKNDPFM_01494 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
EDKNDPFM_01495 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EDKNDPFM_01496 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EDKNDPFM_01497 1.5e-247 trkA P Potassium transporter peripheral membrane component
EDKNDPFM_01498 1.2e-258 trkH P Cation transport protein
EDKNDPFM_01499 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EDKNDPFM_01500 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EDKNDPFM_01501 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EDKNDPFM_01502 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EDKNDPFM_01503 3.7e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
EDKNDPFM_01504 2.1e-85 ykuL S CBS domain
EDKNDPFM_01505 3.5e-99 XK27_09740 S Phosphoesterase
EDKNDPFM_01506 6e-185 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EDKNDPFM_01507 4.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EDKNDPFM_01508 7.6e-36 yneF S UPF0154 protein
EDKNDPFM_01509 1.4e-90 K transcriptional regulator
EDKNDPFM_01510 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EDKNDPFM_01513 8.8e-98 ybhL S Belongs to the BI1 family
EDKNDPFM_01514 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
EDKNDPFM_01515 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EDKNDPFM_01516 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EDKNDPFM_01517 8.5e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EDKNDPFM_01518 5.2e-59 L Integrase core domain protein
EDKNDPFM_01519 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EDKNDPFM_01520 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EDKNDPFM_01521 9.3e-46 XK27_09675 K -acetyltransferase
EDKNDPFM_01522 4e-20 XK27_09675 K -acetyltransferase
EDKNDPFM_01523 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EDKNDPFM_01524 2.5e-23
EDKNDPFM_01525 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
EDKNDPFM_01526 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
EDKNDPFM_01527 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EDKNDPFM_01528 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EDKNDPFM_01529 3.1e-95 ypsA S Belongs to the UPF0398 family
EDKNDPFM_01530 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EDKNDPFM_01531 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EDKNDPFM_01532 1.5e-258 pepC 3.4.22.40 E aminopeptidase
EDKNDPFM_01533 1.9e-77 yhaI L Membrane
EDKNDPFM_01534 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EDKNDPFM_01535 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EDKNDPFM_01536 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
EDKNDPFM_01537 2.6e-76 S thiolester hydrolase activity
EDKNDPFM_01539 3.8e-40 K transcriptional
EDKNDPFM_01540 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EDKNDPFM_01541 3.9e-21 glcR K transcriptional regulator (DeoR family)
EDKNDPFM_01542 4.7e-79 glcR K transcriptional regulator (DeoR family)
EDKNDPFM_01543 1.1e-34 cof Q phosphatase activity
EDKNDPFM_01544 6e-55 cof Q phosphatase activity
EDKNDPFM_01545 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
EDKNDPFM_01546 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
EDKNDPFM_01547 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
EDKNDPFM_01548 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EDKNDPFM_01549 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EDKNDPFM_01550 6.8e-56 S TM2 domain
EDKNDPFM_01551 4.7e-43
EDKNDPFM_01554 8.7e-31 L transposition
EDKNDPFM_01555 6.4e-18 L transposase activity
EDKNDPFM_01556 4.4e-37 L Transposase
EDKNDPFM_01557 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EDKNDPFM_01558 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EDKNDPFM_01559 5.2e-142 cmpC S abc transporter atp-binding protein
EDKNDPFM_01560 0.0 WQ51_06230 S ABC transporter substrate binding protein
EDKNDPFM_01561 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EDKNDPFM_01562 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EDKNDPFM_01563 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
EDKNDPFM_01564 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EDKNDPFM_01565 9.8e-50 yajC U protein transport
EDKNDPFM_01566 1.9e-127 yeeN K transcriptional regulatory protein
EDKNDPFM_01567 8.1e-257 pgi 5.3.1.9 G Belongs to the GPI family
EDKNDPFM_01568 2.6e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
EDKNDPFM_01569 1.5e-104 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EDKNDPFM_01570 5.1e-149 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
EDKNDPFM_01571 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
EDKNDPFM_01572 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
EDKNDPFM_01573 2.5e-128 adcB P ABC transporter (Permease
EDKNDPFM_01574 6.4e-136 adcC P ABC transporter, ATP-binding protein
EDKNDPFM_01575 3.1e-72 adcR K transcriptional
EDKNDPFM_01576 1.9e-223 EGP Major facilitator Superfamily
EDKNDPFM_01577 0.0 KLT serine threonine protein kinase
EDKNDPFM_01579 6e-128 K sequence-specific DNA binding
EDKNDPFM_01580 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EDKNDPFM_01581 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EDKNDPFM_01582 2.7e-21
EDKNDPFM_01583 9.8e-62 oppF P Belongs to the ABC transporter superfamily
EDKNDPFM_01584 7.5e-62 oppF P Belongs to the ABC transporter superfamily
EDKNDPFM_01585 3.1e-43 oppD P Belongs to the ABC transporter superfamily
EDKNDPFM_01586 1.2e-62 oppD P Belongs to the ABC transporter superfamily
EDKNDPFM_01587 1.7e-62 oppD P Belongs to the ABC transporter superfamily
EDKNDPFM_01588 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDKNDPFM_01589 2.5e-09 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDKNDPFM_01590 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDKNDPFM_01591 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDKNDPFM_01592 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
EDKNDPFM_01593 2.3e-139 oppA E ABC transporter substrate-binding protein
EDKNDPFM_01594 7e-10 oppA E ABC transporter substrate-binding protein
EDKNDPFM_01595 2.2e-273 sufB O assembly protein SufB
EDKNDPFM_01596 1.2e-73 nifU C SUF system FeS assembly protein, NifU family
EDKNDPFM_01597 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EDKNDPFM_01598 6.3e-235 sufD O assembly protein SufD
EDKNDPFM_01599 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EDKNDPFM_01600 7.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
EDKNDPFM_01601 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EDKNDPFM_01602 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EDKNDPFM_01603 5.8e-275 glnP P ABC transporter
EDKNDPFM_01604 1e-123 glnQ E abc transporter atp-binding protein
EDKNDPFM_01606 5e-94 V VanZ like family
EDKNDPFM_01607 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EDKNDPFM_01608 9.3e-201 yhjX P Major Facilitator
EDKNDPFM_01609 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EDKNDPFM_01610 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EDKNDPFM_01611 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EDKNDPFM_01612 1.9e-45 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EDKNDPFM_01613 5.6e-59 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EDKNDPFM_01614 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EDKNDPFM_01615 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EDKNDPFM_01616 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EDKNDPFM_01617 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EDKNDPFM_01618 1.8e-83 nrdI F Belongs to the NrdI family
EDKNDPFM_01619 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EDKNDPFM_01620 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EDKNDPFM_01621 9.2e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EDKNDPFM_01622 1.4e-42 F nucleotide catabolic process
EDKNDPFM_01623 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EDKNDPFM_01624 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
EDKNDPFM_01625 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
EDKNDPFM_01626 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
EDKNDPFM_01627 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EDKNDPFM_01628 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EDKNDPFM_01629 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EDKNDPFM_01630 9.3e-150 ykuT M mechanosensitive ion channel
EDKNDPFM_01631 1.6e-77 sigH K DNA-templated transcription, initiation
EDKNDPFM_01632 1e-84
EDKNDPFM_01633 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
EDKNDPFM_01634 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EDKNDPFM_01637 1.9e-86 L Integrase core domain protein
EDKNDPFM_01638 1.6e-55 L transposition
EDKNDPFM_01639 1.1e-92 L Transposase
EDKNDPFM_01640 1.3e-137 L Transposase
EDKNDPFM_01641 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EDKNDPFM_01642 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EDKNDPFM_01643 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EDKNDPFM_01644 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
EDKNDPFM_01646 2.7e-61 divIC D Septum formation initiator
EDKNDPFM_01647 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EDKNDPFM_01648 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EDKNDPFM_01649 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EDKNDPFM_01650 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EDKNDPFM_01651 1.1e-29 yyzM S Protein conserved in bacteria
EDKNDPFM_01652 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EDKNDPFM_01653 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EDKNDPFM_01654 8.5e-134 parB K Belongs to the ParB family
EDKNDPFM_01655 1.1e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
EDKNDPFM_01656 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EDKNDPFM_01657 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
EDKNDPFM_01661 0.0 XK27_10405 S Bacterial membrane protein YfhO
EDKNDPFM_01662 3.3e-305 ybiT S abc transporter atp-binding protein
EDKNDPFM_01663 4.2e-153 yvjA S membrane
EDKNDPFM_01664 3.1e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EDKNDPFM_01665 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EDKNDPFM_01666 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EDKNDPFM_01667 1.6e-45 yaaA S S4 domain protein YaaA
EDKNDPFM_01668 4.8e-235 ymfF S Peptidase M16
EDKNDPFM_01669 3.1e-242 ymfH S Peptidase M16
EDKNDPFM_01670 6.3e-138 ymfM S sequence-specific DNA binding
EDKNDPFM_01671 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EDKNDPFM_01672 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDKNDPFM_01673 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDKNDPFM_01674 1e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EDKNDPFM_01675 1.7e-91 lytE M LysM domain protein
EDKNDPFM_01676 9.9e-64 isaA GH23 M Immunodominant staphylococcal antigen A
EDKNDPFM_01677 0.0 S Bacterial membrane protein, YfhO
EDKNDPFM_01678 4.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EDKNDPFM_01679 1.5e-77 F NUDIX domain
EDKNDPFM_01680 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EDKNDPFM_01681 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EDKNDPFM_01682 3.9e-70 rplI J binds to the 23S rRNA
EDKNDPFM_01683 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EDKNDPFM_01684 8.2e-48 veg S Biofilm formation stimulator VEG
EDKNDPFM_01685 2.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EDKNDPFM_01686 6.4e-141 sip L Phage integrase, N-terminal SAM-like domain
EDKNDPFM_01687 1.4e-12 K sequence-specific DNA binding
EDKNDPFM_01688 3.4e-12 K Helix-turn-helix
EDKNDPFM_01689 6.7e-17
EDKNDPFM_01690 3.8e-13
EDKNDPFM_01691 6.5e-266
EDKNDPFM_01697 2.8e-27 S Transcriptional regulator, RinA family
EDKNDPFM_01698 4.4e-18 yjgN S membrane
EDKNDPFM_01701 2e-53 ypaA S membrane
EDKNDPFM_01702 6.4e-96 XK27_06935 K transcriptional regulator
EDKNDPFM_01703 3.9e-161 XK27_06930 V domain protein
EDKNDPFM_01704 1.8e-88 S Putative adhesin
EDKNDPFM_01705 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
EDKNDPFM_01707 1.7e-23 K negative regulation of transcription, DNA-templated
EDKNDPFM_01708 4e-19 K negative regulation of transcription, DNA-templated
EDKNDPFM_01709 3.4e-13 nudL L hydrolase
EDKNDPFM_01710 1.1e-11 K CsbD-like
EDKNDPFM_01711 3.1e-85 M Protein conserved in bacteria
EDKNDPFM_01712 1.8e-23 S Small integral membrane protein
EDKNDPFM_01713 9.1e-101
EDKNDPFM_01714 1e-29 S Membrane
EDKNDPFM_01716 2.5e-96 S Hydrophobic domain protein
EDKNDPFM_01717 1.5e-49 yegS 2.7.1.107 I lipid kinase activity
EDKNDPFM_01720 1.4e-221 sip L Belongs to the 'phage' integrase family
EDKNDPFM_01721 1.4e-21 S MerR HTH family regulatory protein
EDKNDPFM_01722 2.8e-111 S Plasmid replication protein
EDKNDPFM_01723 1.2e-40
EDKNDPFM_01724 7.4e-184 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EDKNDPFM_01725 6.8e-45
EDKNDPFM_01726 1.9e-30
EDKNDPFM_01727 5.4e-121
EDKNDPFM_01728 7.4e-87 2.7.11.1 K nucleotide-binding Protein
EDKNDPFM_01729 4.6e-64 V Restriction endonuclease
EDKNDPFM_01730 8e-191 L DNA restriction-modification system
EDKNDPFM_01731 1.1e-236 L Helix-turn-helix domain of transposase family ISL3
EDKNDPFM_01732 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EDKNDPFM_01733 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EDKNDPFM_01734 1.4e-36 metE 2.1.1.14 E Methionine synthase
EDKNDPFM_01735 5.2e-55 metE 2.1.1.14 E Methionine synthase
EDKNDPFM_01736 1.4e-53 metE 2.1.1.14 E Methionine synthase
EDKNDPFM_01737 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
EDKNDPFM_01739 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EDKNDPFM_01740 9.3e-167 XK27_01785 S cog cog1284
EDKNDPFM_01741 7e-147 yaaA S Belongs to the UPF0246 family
EDKNDPFM_01742 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EDKNDPFM_01743 1.7e-90 XK27_10930 K acetyltransferase
EDKNDPFM_01744 7.5e-14
EDKNDPFM_01745 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EDKNDPFM_01746 2.8e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
EDKNDPFM_01747 4.2e-44 yrzB S Belongs to the UPF0473 family
EDKNDPFM_01748 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EDKNDPFM_01749 2.2e-44 yrzL S Belongs to the UPF0297 family
EDKNDPFM_01750 5.5e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EDKNDPFM_01751 7.5e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
EDKNDPFM_01753 2.2e-132 int L Belongs to the 'phage' integrase family
EDKNDPFM_01754 2.5e-89 K sequence-specific DNA binding
EDKNDPFM_01755 1.1e-286 V ABC transporter transmembrane region
EDKNDPFM_01756 6.3e-159 C Radical SAM
EDKNDPFM_01757 3.6e-61 C Radical SAM
EDKNDPFM_01759 1.4e-59 Z012_04635 K sequence-specific DNA binding
EDKNDPFM_01760 3.2e-56 Z012_04635 K sequence-specific DNA binding
EDKNDPFM_01761 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EDKNDPFM_01762 3.7e-29 S Domain of unknown function (DUF4649)
EDKNDPFM_01763 6.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EDKNDPFM_01765 1.7e-60 hmpT S membrane
EDKNDPFM_01766 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
EDKNDPFM_01767 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EDKNDPFM_01768 9.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EDKNDPFM_01769 7.5e-298 dnaK O Heat shock 70 kDa protein
EDKNDPFM_01770 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EDKNDPFM_01771 5.8e-197 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EDKNDPFM_01772 1.3e-102 acmA 3.2.1.17 NU amidase activity
EDKNDPFM_01773 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EDKNDPFM_01774 2.2e-38 ais G alpha-ribazole phosphatase activity
EDKNDPFM_01775 1.9e-242 XK27_08635 S UPF0210 protein
EDKNDPFM_01776 3.6e-39 gcvR T UPF0237 protein
EDKNDPFM_01777 3.3e-225 capA M Bacterial capsule synthesis protein
EDKNDPFM_01778 5.7e-91 tnp L Transposase
EDKNDPFM_01779 3.4e-75 isp2 S pathogenesis
EDKNDPFM_01781 4.9e-173
EDKNDPFM_01782 2.8e-39 S Helix-turn-helix domain
EDKNDPFM_01783 5.9e-222 int L Belongs to the 'phage' integrase family
EDKNDPFM_01784 2.9e-90 3.6.4.12 K Divergent AAA domain protein
EDKNDPFM_01785 5.9e-24 3.6.4.12
EDKNDPFM_01786 2.5e-183 EGP Major facilitator Superfamily
EDKNDPFM_01787 9.1e-231 spaC2 V Lanthionine synthetase C family protein
EDKNDPFM_01788 0.0 S Lantibiotic dehydratase, C terminus
EDKNDPFM_01790 1.5e-35 K sequence-specific DNA binding
EDKNDPFM_01791 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
EDKNDPFM_01792 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EDKNDPFM_01793 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EDKNDPFM_01794 1.8e-31 K helix-turn-helix
EDKNDPFM_01796 3.4e-155 degV S DegV family
EDKNDPFM_01797 3.5e-91 yacP S RNA-binding protein containing a PIN domain
EDKNDPFM_01798 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EDKNDPFM_01801 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EDKNDPFM_01802 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EDKNDPFM_01803 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
EDKNDPFM_01804 7.9e-106 S SseB protein N-terminal domain
EDKNDPFM_01805 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EDKNDPFM_01806 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EDKNDPFM_01807 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EDKNDPFM_01808 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EDKNDPFM_01809 0.0 clpC O Belongs to the ClpA ClpB family
EDKNDPFM_01810 6.2e-76 ctsR K Belongs to the CtsR family
EDKNDPFM_01811 1.1e-83 S Putative small multi-drug export protein
EDKNDPFM_01812 3e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EDKNDPFM_01813 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
EDKNDPFM_01816 7.1e-80 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EDKNDPFM_01817 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
EDKNDPFM_01819 6.4e-41 L transposition
EDKNDPFM_01820 6.9e-89 L Integrase core domain protein
EDKNDPFM_01821 3.5e-97 S reductase
EDKNDPFM_01822 2.6e-55 badR K DNA-binding transcription factor activity
EDKNDPFM_01823 5.5e-36 XK27_02060 S Transglycosylase associated protein
EDKNDPFM_01824 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EDKNDPFM_01825 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EDKNDPFM_01830 1.9e-07
EDKNDPFM_01833 2.6e-10
EDKNDPFM_01838 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
EDKNDPFM_01839 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EDKNDPFM_01840 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
EDKNDPFM_01841 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
EDKNDPFM_01842 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EDKNDPFM_01844 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EDKNDPFM_01846 6.5e-63 KT phosphorelay signal transduction system
EDKNDPFM_01847 1.9e-80 S Protein of unknown function (DUF3021)
EDKNDPFM_01848 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EDKNDPFM_01849 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EDKNDPFM_01850 8.2e-70 argR K Regulates arginine biosynthesis genes
EDKNDPFM_01852 1.2e-57 T Toxic component of a toxin-antitoxin (TA) module
EDKNDPFM_01855 3.5e-28 3.4.13.21 I Protein conserved in bacteria
EDKNDPFM_01856 1.7e-87 FNV0100 F Belongs to the Nudix hydrolase family
EDKNDPFM_01857 4.2e-35 amiA E ABC transporter, substrate-binding protein, family 5
EDKNDPFM_01858 1.2e-09 L Transposase
EDKNDPFM_01859 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EDKNDPFM_01860 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EDKNDPFM_01861 2e-140 1.1.1.169 H Ketopantoate reductase
EDKNDPFM_01862 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EDKNDPFM_01863 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EDKNDPFM_01864 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
EDKNDPFM_01865 2.3e-161 S CHAP domain
EDKNDPFM_01866 2e-32 L Integrase core domain protein
EDKNDPFM_01867 3.5e-50 L transposition
EDKNDPFM_01868 1e-90 L transposase activity
EDKNDPFM_01869 1.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EDKNDPFM_01870 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EDKNDPFM_01871 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EDKNDPFM_01872 2.9e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EDKNDPFM_01873 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EDKNDPFM_01874 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EDKNDPFM_01875 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EDKNDPFM_01876 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EDKNDPFM_01877 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
EDKNDPFM_01878 2.9e-218 araT 2.6.1.1 E Aminotransferase
EDKNDPFM_01879 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EDKNDPFM_01880 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
EDKNDPFM_01881 9.1e-87 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EDKNDPFM_01882 5.5e-139 mreC M Involved in formation and maintenance of cell shape
EDKNDPFM_01888 5.3e-11
EDKNDPFM_01900 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
EDKNDPFM_01901 2e-09 L thioesterase
EDKNDPFM_01902 6.6e-142 S Macro domain protein
EDKNDPFM_01903 4.8e-51 trxA O Belongs to the thioredoxin family
EDKNDPFM_01904 2.5e-74 yccU S CoA-binding protein
EDKNDPFM_01905 4.1e-144 tatD L Hydrolase, tatd
EDKNDPFM_01906 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EDKNDPFM_01907 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EDKNDPFM_01909 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EDKNDPFM_01910 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EDKNDPFM_01911 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
EDKNDPFM_01912 6.9e-173 rmuC S RmuC domain protein
EDKNDPFM_01913 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
EDKNDPFM_01914 1.1e-142 purR 2.4.2.7 F operon repressor
EDKNDPFM_01915 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EDKNDPFM_01916 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EDKNDPFM_01917 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EDKNDPFM_01918 9.3e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EDKNDPFM_01919 6.1e-114 L Transposase
EDKNDPFM_01920 1e-102 L Transposase
EDKNDPFM_01921 1.8e-56 L transposition
EDKNDPFM_01922 7.4e-23 L Transposase
EDKNDPFM_01923 1.9e-46 L transposase activity
EDKNDPFM_01924 3.2e-42 L Transposase
EDKNDPFM_01925 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EDKNDPFM_01926 1.3e-87 S Fusaric acid resistance protein-like
EDKNDPFM_01927 8.5e-63 glnR K Transcriptional regulator
EDKNDPFM_01928 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
EDKNDPFM_01929 2.7e-40 pscB M CHAP domain protein
EDKNDPFM_01930 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EDKNDPFM_01931 2.5e-33 ykzG S Belongs to the UPF0356 family
EDKNDPFM_01932 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
EDKNDPFM_01933 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EDKNDPFM_01934 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EDKNDPFM_01935 1.8e-114 azlC E AzlC protein
EDKNDPFM_01936 2e-47 azlD E branched-chain amino acid
EDKNDPFM_01937 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EDKNDPFM_01938 1.8e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EDKNDPFM_01939 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EDKNDPFM_01940 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EDKNDPFM_01941 1e-93 cvpA S toxin biosynthetic process
EDKNDPFM_01942 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EDKNDPFM_01943 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EDKNDPFM_01949 6.1e-229 mutY L A G-specific adenine glycosylase
EDKNDPFM_01950 9.5e-42 XK27_05745
EDKNDPFM_01951 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
EDKNDPFM_01952 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EDKNDPFM_01953 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EDKNDPFM_01955 3.1e-124 XK27_01040 S Pfam PF06570
EDKNDPFM_01956 2e-169 corA P COG0598 Mg2 and Co2 transporters
EDKNDPFM_01957 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EDKNDPFM_01960 1e-58 V 'abc transporter, ATP-binding protein
EDKNDPFM_01961 8e-44 V 'abc transporter, ATP-binding protein
EDKNDPFM_01963 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
EDKNDPFM_01964 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
EDKNDPFM_01965 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EDKNDPFM_01966 3.4e-62 yqhY S protein conserved in bacteria
EDKNDPFM_01967 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EDKNDPFM_01968 7.5e-180 scrR K Transcriptional
EDKNDPFM_01969 5.4e-291 scrB 3.2.1.26 GH32 G invertase
EDKNDPFM_01970 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
EDKNDPFM_01971 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
EDKNDPFM_01972 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
EDKNDPFM_01974 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EDKNDPFM_01975 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EDKNDPFM_01976 7.2e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EDKNDPFM_01977 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EDKNDPFM_01978 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EDKNDPFM_01979 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EDKNDPFM_01980 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EDKNDPFM_01981 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
EDKNDPFM_01982 2.9e-18 yebC M Membrane
EDKNDPFM_01983 5.2e-81 yebC M Membrane
EDKNDPFM_01984 1.8e-65 KT response to antibiotic
EDKNDPFM_01985 7e-10 XK27_02470 K LytTr DNA-binding domain protein
EDKNDPFM_01986 7.6e-66 liaI S membrane
EDKNDPFM_01987 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EDKNDPFM_01988 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EDKNDPFM_01989 5.2e-125 S Protein of unknown function (DUF554)
EDKNDPFM_01990 8.1e-134 ecsA_2 V abc transporter atp-binding protein
EDKNDPFM_01991 2.2e-285 XK27_00765
EDKNDPFM_01992 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EDKNDPFM_01993 4.5e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EDKNDPFM_01994 1.1e-12 D nuclear chromosome segregation
EDKNDPFM_01995 9.7e-32 yhaI J Protein of unknown function (DUF805)
EDKNDPFM_01996 3e-128
EDKNDPFM_01997 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EDKNDPFM_01998 8.1e-46 ftsL D cell division protein FtsL
EDKNDPFM_01999 0.0 ftsI 3.4.16.4 M penicillin-binding protein
EDKNDPFM_02000 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EDKNDPFM_02001 6.1e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EDKNDPFM_02003 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EDKNDPFM_02004 2.3e-72 yutD J protein conserved in bacteria
EDKNDPFM_02005 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EDKNDPFM_02006 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
EDKNDPFM_02008 0.0 mdlA V abc transporter atp-binding protein
EDKNDPFM_02009 0.0 mdlB V abc transporter atp-binding protein
EDKNDPFM_02010 2.8e-108 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDKNDPFM_02011 9.3e-281 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EDKNDPFM_02012 7.3e-237 mesE M Transport protein ComB
EDKNDPFM_02014 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
EDKNDPFM_02015 7.4e-135 agrA KT phosphorelay signal transduction system
EDKNDPFM_02018 4.3e-25 S Bacteriocin class II with double-glycine leader peptide

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)