ORF_ID e_value Gene_name EC_number CAZy COGs Description
KIKKMPBN_00001 1.9e-86 L Integrase core domain protein
KIKKMPBN_00002 1.6e-55 L transposition
KIKKMPBN_00003 1.1e-92 L Transposase
KIKKMPBN_00004 1.3e-137 L Transposase
KIKKMPBN_00005 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KIKKMPBN_00006 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KIKKMPBN_00007 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KIKKMPBN_00008 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KIKKMPBN_00010 2.7e-61 divIC D Septum formation initiator
KIKKMPBN_00011 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KIKKMPBN_00012 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KIKKMPBN_00013 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KIKKMPBN_00014 4.3e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KIKKMPBN_00015 1.1e-29 yyzM S Protein conserved in bacteria
KIKKMPBN_00016 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KIKKMPBN_00017 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KIKKMPBN_00018 8.5e-134 parB K Belongs to the ParB family
KIKKMPBN_00019 1.1e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KIKKMPBN_00020 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KIKKMPBN_00021 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
KIKKMPBN_00025 0.0 XK27_10405 S Bacterial membrane protein YfhO
KIKKMPBN_00026 3.3e-305 ybiT S abc transporter atp-binding protein
KIKKMPBN_00027 4.2e-153 yvjA S membrane
KIKKMPBN_00028 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KIKKMPBN_00029 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KIKKMPBN_00030 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KIKKMPBN_00031 2.4e-44 yaaA S S4 domain protein YaaA
KIKKMPBN_00032 3.1e-234 ymfF S Peptidase M16
KIKKMPBN_00033 3.1e-242 ymfH S Peptidase M16
KIKKMPBN_00034 6.3e-138 ymfM S sequence-specific DNA binding
KIKKMPBN_00035 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KIKKMPBN_00036 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIKKMPBN_00037 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIKKMPBN_00038 1e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KIKKMPBN_00039 1.7e-91 lytE M LysM domain protein
KIKKMPBN_00040 1.1e-62 isaA GH23 M Immunodominant staphylococcal antigen A
KIKKMPBN_00041 0.0 S Bacterial membrane protein, YfhO
KIKKMPBN_00042 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KIKKMPBN_00043 6.5e-68 F NUDIX domain
KIKKMPBN_00044 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KIKKMPBN_00045 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KIKKMPBN_00046 3.9e-70 rplI J binds to the 23S rRNA
KIKKMPBN_00047 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KIKKMPBN_00048 8.2e-48 veg S Biofilm formation stimulator VEG
KIKKMPBN_00049 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KIKKMPBN_00050 2.7e-08
KIKKMPBN_00051 4.8e-55 ypaA M Membrane
KIKKMPBN_00052 6.4e-96 XK27_06935 K transcriptional regulator
KIKKMPBN_00053 3.9e-161 XK27_06930 V domain protein
KIKKMPBN_00054 1.8e-88 S Putative adhesin
KIKKMPBN_00055 4e-19 XK27_06920 S Protein of unknown function (DUF1700)
KIKKMPBN_00057 1.7e-23 K negative regulation of transcription, DNA-templated
KIKKMPBN_00058 4e-19 K negative regulation of transcription, DNA-templated
KIKKMPBN_00059 3.4e-13 nudL L hydrolase
KIKKMPBN_00060 1.1e-11 K CsbD-like
KIKKMPBN_00061 3.1e-85 M Protein conserved in bacteria
KIKKMPBN_00062 1.8e-23 S Small integral membrane protein
KIKKMPBN_00063 9.1e-101
KIKKMPBN_00064 1e-29 S Membrane
KIKKMPBN_00066 2.5e-96 S Hydrophobic domain protein
KIKKMPBN_00067 2.6e-49 yegS 2.7.1.107 I lipid kinase activity
KIKKMPBN_00070 5.1e-184 sip L Belongs to the 'phage' integrase family
KIKKMPBN_00071 2.7e-20 S MerR HTH family regulatory protein
KIKKMPBN_00072 2.8e-82 S Plasmid replication protein
KIKKMPBN_00073 1.5e-20
KIKKMPBN_00074 6.1e-162 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KIKKMPBN_00075 1.7e-35
KIKKMPBN_00076 3.6e-09 S Sigma-70, region 4
KIKKMPBN_00077 0.0 V Type II restriction enzyme, methylase subunits
KIKKMPBN_00078 8.3e-29
KIKKMPBN_00079 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KIKKMPBN_00080 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KIKKMPBN_00081 1.4e-36 metE 2.1.1.14 E Methionine synthase
KIKKMPBN_00082 5.2e-55 metE 2.1.1.14 E Methionine synthase
KIKKMPBN_00083 1.4e-53 metE 2.1.1.14 E Methionine synthase
KIKKMPBN_00084 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
KIKKMPBN_00086 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KIKKMPBN_00087 9.3e-167 XK27_01785 S cog cog1284
KIKKMPBN_00088 7e-147 yaaA S Belongs to the UPF0246 family
KIKKMPBN_00089 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KIKKMPBN_00090 1.7e-90 XK27_10930 K acetyltransferase
KIKKMPBN_00091 7.5e-14
KIKKMPBN_00092 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KIKKMPBN_00093 2.8e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
KIKKMPBN_00094 4.2e-44 yrzB S Belongs to the UPF0473 family
KIKKMPBN_00095 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KIKKMPBN_00096 2.2e-44 yrzL S Belongs to the UPF0297 family
KIKKMPBN_00097 5.5e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KIKKMPBN_00098 7.5e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KIKKMPBN_00100 2.2e-132 int L Belongs to the 'phage' integrase family
KIKKMPBN_00101 2.5e-89 K sequence-specific DNA binding
KIKKMPBN_00102 5.1e-287 V ABC transporter transmembrane region
KIKKMPBN_00103 6.3e-159 C Radical SAM
KIKKMPBN_00104 3.6e-61 C Radical SAM
KIKKMPBN_00106 1.4e-59 Z012_04635 K sequence-specific DNA binding
KIKKMPBN_00107 3.2e-56 Z012_04635 K sequence-specific DNA binding
KIKKMPBN_00108 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KIKKMPBN_00109 9.7e-30 S Domain of unknown function (DUF4649)
KIKKMPBN_00110 6.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KIKKMPBN_00111 6.7e-98 blpT
KIKKMPBN_00112 2.9e-28 blpT
KIKKMPBN_00113 3e-47 spiA K sequence-specific DNA binding
KIKKMPBN_00116 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KIKKMPBN_00117 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KIKKMPBN_00118 5e-44 V CAAX protease self-immunity
KIKKMPBN_00119 4.6e-140 cppA E CppA N-terminal
KIKKMPBN_00120 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KIKKMPBN_00121 1.2e-117 ybbL S abc transporter atp-binding protein
KIKKMPBN_00122 1.5e-127 ybbM S transport system, permease component
KIKKMPBN_00123 2.9e-87 D nuclear chromosome segregation
KIKKMPBN_00124 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
KIKKMPBN_00125 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KIKKMPBN_00126 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
KIKKMPBN_00127 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KIKKMPBN_00128 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIKKMPBN_00130 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KIKKMPBN_00131 1e-162 yxeN P ABC transporter (Permease
KIKKMPBN_00132 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
KIKKMPBN_00133 1.9e-09 S Protein of unknown function (DUF4059)
KIKKMPBN_00134 3.2e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KIKKMPBN_00135 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
KIKKMPBN_00136 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KIKKMPBN_00137 2.2e-196 ylbL T Belongs to the peptidase S16 family
KIKKMPBN_00138 3.8e-184 yhcC S radical SAM protein
KIKKMPBN_00139 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
KIKKMPBN_00141 0.0 yjcE P NhaP-type Na H and K H antiporters
KIKKMPBN_00142 1.2e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KIKKMPBN_00143 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KIKKMPBN_00144 6.3e-156 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KIKKMPBN_00147 2.4e-75 XK27_03180 T universal stress protein
KIKKMPBN_00148 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KIKKMPBN_00149 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KIKKMPBN_00150 6.8e-101 pncA Q isochorismatase
KIKKMPBN_00151 1.5e-124 hlpA M Belongs to the NlpA lipoprotein family
KIKKMPBN_00152 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIKKMPBN_00153 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KIKKMPBN_00154 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KIKKMPBN_00155 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIKKMPBN_00156 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KIKKMPBN_00157 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KIKKMPBN_00158 1.2e-58
KIKKMPBN_00159 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KIKKMPBN_00160 1.8e-98 yqeG S hydrolase of the HAD superfamily
KIKKMPBN_00161 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KIKKMPBN_00162 3.5e-49 yhbY J RNA-binding protein
KIKKMPBN_00163 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KIKKMPBN_00164 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KIKKMPBN_00165 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KIKKMPBN_00166 2e-140 yqeM Q Methyltransferase domain protein
KIKKMPBN_00167 6.9e-206 ylbM S Belongs to the UPF0348 family
KIKKMPBN_00168 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KIKKMPBN_00170 7.3e-107
KIKKMPBN_00171 2.6e-55 S CD20-like family
KIKKMPBN_00172 5.6e-12
KIKKMPBN_00173 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KIKKMPBN_00174 2.3e-133 ecsA V abc transporter atp-binding protein
KIKKMPBN_00175 2.7e-183 ecsB U ABC transporter
KIKKMPBN_00176 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
KIKKMPBN_00177 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KIKKMPBN_00179 7.7e-227 ytfP S Flavoprotein
KIKKMPBN_00180 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KIKKMPBN_00181 7.4e-64 XK27_02560 S cog cog2151
KIKKMPBN_00182 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
KIKKMPBN_00183 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
KIKKMPBN_00184 2.7e-129 K transcriptional regulator, MerR family
KIKKMPBN_00185 9.7e-28 L transposase activity
KIKKMPBN_00186 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KIKKMPBN_00187 3.9e-26
KIKKMPBN_00188 0.0 ctpE P E1-E2 ATPase
KIKKMPBN_00189 3.2e-56
KIKKMPBN_00190 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
KIKKMPBN_00191 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KIKKMPBN_00192 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KIKKMPBN_00193 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KIKKMPBN_00194 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KIKKMPBN_00195 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KIKKMPBN_00196 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KIKKMPBN_00197 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KIKKMPBN_00198 2.7e-73 copY K Copper transport repressor, CopY TcrY family
KIKKMPBN_00199 0.0 copA 3.6.3.54 P P-type ATPase
KIKKMPBN_00200 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
KIKKMPBN_00201 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KIKKMPBN_00202 6e-115 papP P ABC transporter (Permease
KIKKMPBN_00203 3e-106 P ABC transporter (Permease
KIKKMPBN_00204 7.6e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
KIKKMPBN_00205 1.1e-155 cjaA ET ABC transporter substrate-binding protein
KIKKMPBN_00209 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KIKKMPBN_00210 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
KIKKMPBN_00211 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KIKKMPBN_00212 1.9e-201 yjbB G Permeases of the major facilitator superfamily
KIKKMPBN_00213 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KIKKMPBN_00214 7.8e-100 thiT S Thiamine transporter
KIKKMPBN_00215 1.9e-62 yjqA S Bacterial PH domain
KIKKMPBN_00216 2.3e-154 corA P CorA-like protein
KIKKMPBN_00217 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KIKKMPBN_00218 1e-41 yazA L endonuclease containing a URI domain
KIKKMPBN_00219 2.3e-139 yabB 2.1.1.223 L Methyltransferase
KIKKMPBN_00220 4.1e-22 nodB3 G polysaccharide deacetylase
KIKKMPBN_00221 1.7e-77 nodB3 G polysaccharide deacetylase
KIKKMPBN_00222 1.3e-142 plsC 2.3.1.51 I Acyltransferase
KIKKMPBN_00223 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KIKKMPBN_00224 0.0 comEC S Competence protein ComEC
KIKKMPBN_00225 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIKKMPBN_00226 7e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KIKKMPBN_00227 3.6e-230 ytoI K transcriptional regulator containing CBS domains
KIKKMPBN_00228 2.1e-165 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KIKKMPBN_00229 7.4e-164 rbn E Belongs to the UPF0761 family
KIKKMPBN_00230 3.7e-85 ccl S cog cog4708
KIKKMPBN_00231 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KIKKMPBN_00232 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KIKKMPBN_00233 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KIKKMPBN_00234 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KIKKMPBN_00235 2.1e-74 S QueT transporter
KIKKMPBN_00236 2.6e-157 xth 3.1.11.2 L exodeoxyribonuclease III
KIKKMPBN_00237 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KIKKMPBN_00238 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KIKKMPBN_00239 4.1e-37 ylqC L Belongs to the UPF0109 family
KIKKMPBN_00240 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KIKKMPBN_00241 0.0 ydaO E amino acid
KIKKMPBN_00242 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
KIKKMPBN_00243 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KIKKMPBN_00244 3.5e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KIKKMPBN_00245 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KIKKMPBN_00246 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KIKKMPBN_00247 7.8e-171 murB 1.3.1.98 M cell wall formation
KIKKMPBN_00248 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KIKKMPBN_00249 8.2e-140 potB P ABC-type spermidine putrescine transport system, permease component I
KIKKMPBN_00250 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
KIKKMPBN_00251 2.3e-206 potD P spermidine putrescine ABC transporter
KIKKMPBN_00252 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
KIKKMPBN_00253 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
KIKKMPBN_00254 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
KIKKMPBN_00255 4.6e-115 GK ROK family
KIKKMPBN_00256 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KIKKMPBN_00257 8.7e-104 wecD M Acetyltransferase GNAT family
KIKKMPBN_00258 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KIKKMPBN_00259 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KIKKMPBN_00260 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
KIKKMPBN_00262 2e-56 lrgA S Effector of murein hydrolase LrgA
KIKKMPBN_00263 2.2e-117 lrgB M effector of murein hydrolase
KIKKMPBN_00264 2.6e-109 3.1.3.18 S IA, variant 1
KIKKMPBN_00265 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIKKMPBN_00266 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KIKKMPBN_00267 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
KIKKMPBN_00268 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KIKKMPBN_00269 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIKKMPBN_00270 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIKKMPBN_00271 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
KIKKMPBN_00273 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
KIKKMPBN_00275 6.6e-30 ycaO O OsmC-like protein
KIKKMPBN_00276 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
KIKKMPBN_00279 6.2e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KIKKMPBN_00281 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KIKKMPBN_00282 1.1e-16 XK27_00735
KIKKMPBN_00283 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KIKKMPBN_00284 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KIKKMPBN_00285 2.4e-33 S CAAX amino terminal protease family protein
KIKKMPBN_00286 4.3e-82 S CAAX amino terminal protease family protein
KIKKMPBN_00288 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KIKKMPBN_00289 2.9e-84 mutT 3.6.1.55 F Nudix family
KIKKMPBN_00290 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
KIKKMPBN_00291 9.4e-136 ET ABC transporter
KIKKMPBN_00292 2.1e-202 arcT 2.6.1.1 E Aminotransferase
KIKKMPBN_00293 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
KIKKMPBN_00294 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KIKKMPBN_00295 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KIKKMPBN_00296 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KIKKMPBN_00297 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KIKKMPBN_00298 1.4e-251 M Psort location CytoplasmicMembrane, score
KIKKMPBN_00299 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KIKKMPBN_00300 3.2e-245
KIKKMPBN_00301 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KIKKMPBN_00302 7.6e-126 ycbB S Glycosyl transferase family 2
KIKKMPBN_00303 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
KIKKMPBN_00304 2.6e-220 amrA S polysaccharide biosynthetic process
KIKKMPBN_00305 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
KIKKMPBN_00306 1.3e-226 rgpA GT4 M Domain of unknown function (DUF1972)
KIKKMPBN_00307 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
KIKKMPBN_00308 2.8e-143 rgpC GM Transport permease protein
KIKKMPBN_00309 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KIKKMPBN_00310 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KIKKMPBN_00311 0.0 rgpF M Rhamnan synthesis protein F
KIKKMPBN_00312 2.4e-119 radC E Belongs to the UPF0758 family
KIKKMPBN_00313 2.7e-131 puuD T peptidase C26
KIKKMPBN_00314 6.1e-120 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KIKKMPBN_00315 9e-59 XK27_04120 S Putative amino acid metabolism
KIKKMPBN_00316 1.2e-205 iscS 2.8.1.7 E Cysteine desulfurase
KIKKMPBN_00317 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIKKMPBN_00318 1.5e-103 yjbK S Adenylate cyclase
KIKKMPBN_00319 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KIKKMPBN_00320 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KIKKMPBN_00321 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KIKKMPBN_00322 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KIKKMPBN_00323 8.9e-18 L transposase activity
KIKKMPBN_00324 1.1e-23 L transposase activity
KIKKMPBN_00325 1e-110 L Integrase core domain protein
KIKKMPBN_00326 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
KIKKMPBN_00327 1.4e-40 tatD L Hydrolase, tatd
KIKKMPBN_00328 3.8e-45 oppF P Belongs to the ABC transporter superfamily
KIKKMPBN_00329 1.2e-24 oppF P Belongs to the ABC transporter superfamily
KIKKMPBN_00330 4.1e-158 L COG2801 Transposase and inactivated derivatives
KIKKMPBN_00331 8.1e-45 L Transposase
KIKKMPBN_00332 4.4e-98 amiA E ABC transporter, substrate-binding protein, family 5
KIKKMPBN_00333 2.1e-277 amiC P ABC transporter (Permease
KIKKMPBN_00334 4.9e-168 amiD P ABC transporter (Permease
KIKKMPBN_00335 2.2e-204 oppD P Belongs to the ABC transporter superfamily
KIKKMPBN_00336 4.3e-172 oppF P Belongs to the ABC transporter superfamily
KIKKMPBN_00337 3.3e-133 V ATPase activity
KIKKMPBN_00338 2.8e-120 skfE V abc transporter atp-binding protein
KIKKMPBN_00339 8.6e-63 yvoA_1 K Transcriptional
KIKKMPBN_00340 8.5e-145 supH S overlaps another CDS with the same product name
KIKKMPBN_00341 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
KIKKMPBN_00342 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KIKKMPBN_00343 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KIKKMPBN_00344 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KIKKMPBN_00345 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KIKKMPBN_00346 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KIKKMPBN_00347 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KIKKMPBN_00348 2e-132 stp 3.1.3.16 T phosphatase
KIKKMPBN_00349 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KIKKMPBN_00350 3.7e-120 yvqF KT membrane
KIKKMPBN_00351 5.8e-175 vraS 2.7.13.3 T Histidine kinase
KIKKMPBN_00352 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KIKKMPBN_00355 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KIKKMPBN_00356 2.1e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KIKKMPBN_00357 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KIKKMPBN_00358 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KIKKMPBN_00359 4.9e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KIKKMPBN_00360 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KIKKMPBN_00361 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KIKKMPBN_00362 6.4e-62 L Transposase
KIKKMPBN_00363 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KIKKMPBN_00364 4.3e-40 V abc transporter atp-binding protein
KIKKMPBN_00365 2.5e-101 V abc transporter atp-binding protein
KIKKMPBN_00366 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KIKKMPBN_00367 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KIKKMPBN_00368 1.2e-25 L transposition
KIKKMPBN_00369 2.7e-08 L Integrase core domain protein
KIKKMPBN_00370 2.3e-184 galR K Transcriptional regulator
KIKKMPBN_00371 8.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KIKKMPBN_00372 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KIKKMPBN_00373 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KIKKMPBN_00374 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KIKKMPBN_00375 0.0 lacS G transporter
KIKKMPBN_00376 0.0 lacL 3.2.1.23 G -beta-galactosidase
KIKKMPBN_00377 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KIKKMPBN_00378 0.0 sbcC L ATPase involved in DNA repair
KIKKMPBN_00379 2.8e-85
KIKKMPBN_00381 1.8e-87 L transposase activity
KIKKMPBN_00382 1.4e-150 L Integrase core domain protein
KIKKMPBN_00383 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KIKKMPBN_00385 6.1e-257 I radical SAM domain protein
KIKKMPBN_00386 1.2e-176 EGP Major Facilitator Superfamily
KIKKMPBN_00387 3.9e-110 C Fe-S oxidoreductases
KIKKMPBN_00389 1.1e-151 V MatE
KIKKMPBN_00390 1.7e-102 amiA E ABC transporter, substrate-binding protein, family 5
KIKKMPBN_00391 9.7e-149 L Transposase
KIKKMPBN_00392 4.8e-117 devA 3.6.3.25 V abc transporter atp-binding protein
KIKKMPBN_00393 2.8e-164 hrtB V MacB-like periplasmic core domain
KIKKMPBN_00395 0.0 M family 8
KIKKMPBN_00396 2.7e-09
KIKKMPBN_00397 5.6e-08
KIKKMPBN_00398 5.8e-109 MA20_06410 E LysE type translocator
KIKKMPBN_00399 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
KIKKMPBN_00400 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
KIKKMPBN_00401 1e-137
KIKKMPBN_00402 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIKKMPBN_00403 4.5e-61
KIKKMPBN_00404 9.3e-72 S Signal peptide protein, YSIRK family
KIKKMPBN_00405 1.4e-54 K response regulator
KIKKMPBN_00406 1.1e-37 BP1961 P nitric oxide dioxygenase activity
KIKKMPBN_00408 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
KIKKMPBN_00409 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KIKKMPBN_00410 6.8e-161 yvgN C reductase
KIKKMPBN_00412 3e-102 yoaK S Protein of unknown function (DUF1275)
KIKKMPBN_00413 1.4e-110 drgA C Nitroreductase
KIKKMPBN_00414 5.6e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KIKKMPBN_00415 8.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
KIKKMPBN_00416 4.7e-76 ywnA K Transcriptional regulator
KIKKMPBN_00417 9.5e-150 1.13.11.2 S glyoxalase
KIKKMPBN_00418 5.1e-110 XK27_02070 S nitroreductase
KIKKMPBN_00420 2.1e-71 ydhF S Aldo keto reductase
KIKKMPBN_00421 9.4e-68 ydhF S Aldo keto reductase
KIKKMPBN_00422 3.9e-82 K WHG domain
KIKKMPBN_00423 3.2e-91 V abc transporter atp-binding protein
KIKKMPBN_00424 5.9e-23 P FtsX-like permease family
KIKKMPBN_00425 2.4e-40 S Sugar efflux transporter for intercellular exchange
KIKKMPBN_00426 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KIKKMPBN_00427 8.1e-161 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
KIKKMPBN_00428 1.8e-161 ET ABC transporter substrate-binding protein
KIKKMPBN_00429 6.1e-107 ytmL P ABC transporter (Permease
KIKKMPBN_00430 3e-114 yxeN P ABC transporter, permease protein
KIKKMPBN_00431 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
KIKKMPBN_00434 1.6e-21 L Integrase core domain protein
KIKKMPBN_00435 1.1e-139 S dextransucrase activity
KIKKMPBN_00436 4.9e-228 S dextransucrase activity
KIKKMPBN_00437 6.2e-228 yfnA E amino acid
KIKKMPBN_00439 9.6e-26 csbD K CsbD-like
KIKKMPBN_00440 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
KIKKMPBN_00441 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
KIKKMPBN_00442 5.6e-234 brnQ E Component of the transport system for branched-chain amino acids
KIKKMPBN_00443 6.7e-129 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIKKMPBN_00444 6.7e-35 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIKKMPBN_00445 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
KIKKMPBN_00446 1.5e-78 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
KIKKMPBN_00447 5.6e-145 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KIKKMPBN_00448 3e-115 yxeQ S MmgE/PrpD family
KIKKMPBN_00449 4.1e-58 yxeL K Acetyltransferase (GNAT) domain
KIKKMPBN_00450 4.1e-63 yxeN U ABC transporter, permease protein
KIKKMPBN_00451 7.3e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
KIKKMPBN_00452 2.9e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
KIKKMPBN_00453 3.5e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
KIKKMPBN_00454 6.3e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KIKKMPBN_00455 3.4e-247 norM V Multidrug efflux pump
KIKKMPBN_00456 4.6e-118 pbuX F xanthine permease
KIKKMPBN_00457 3.3e-69 pbuX F xanthine permease
KIKKMPBN_00458 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KIKKMPBN_00459 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIKKMPBN_00460 6.2e-166 T Histidine kinase
KIKKMPBN_00461 1.9e-133 macB2 V ABC transporter, ATP-binding protein
KIKKMPBN_00462 0.0 V ABC transporter (permease)
KIKKMPBN_00463 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
KIKKMPBN_00464 2.6e-30 liaI KT membrane
KIKKMPBN_00465 2.7e-14 liaI KT membrane
KIKKMPBN_00466 1e-151 XK27_09825 V abc transporter atp-binding protein
KIKKMPBN_00467 1.7e-114 yvfS V Transporter
KIKKMPBN_00468 3.1e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
KIKKMPBN_00469 3.6e-163 yocS S Transporter
KIKKMPBN_00472 7.4e-158 XK27_09825 V abc transporter atp-binding protein
KIKKMPBN_00473 1.4e-133 yvfS V ABC-2 type transporter
KIKKMPBN_00474 1.5e-192 desK 2.7.13.3 T Histidine kinase
KIKKMPBN_00475 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KIKKMPBN_00476 3.6e-97 S transport system, permease component
KIKKMPBN_00477 1.1e-144 S ABC-2 family transporter protein
KIKKMPBN_00478 7.4e-26
KIKKMPBN_00479 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
KIKKMPBN_00480 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
KIKKMPBN_00481 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KIKKMPBN_00482 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KIKKMPBN_00483 4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KIKKMPBN_00484 6.3e-23
KIKKMPBN_00485 3e-13
KIKKMPBN_00486 2.4e-92 pat 2.3.1.183 M acetyltransferase
KIKKMPBN_00487 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KIKKMPBN_00488 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KIKKMPBN_00489 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KIKKMPBN_00490 0.0 smc D Required for chromosome condensation and partitioning
KIKKMPBN_00491 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KIKKMPBN_00492 2.9e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KIKKMPBN_00493 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KIKKMPBN_00495 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KIKKMPBN_00496 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KIKKMPBN_00498 2e-86 S ECF-type riboflavin transporter, S component
KIKKMPBN_00499 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KIKKMPBN_00500 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KIKKMPBN_00501 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
KIKKMPBN_00502 1.9e-294 yfmM S abc transporter atp-binding protein
KIKKMPBN_00503 3.4e-258 noxE P NADH oxidase
KIKKMPBN_00504 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KIKKMPBN_00505 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KIKKMPBN_00506 2.1e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KIKKMPBN_00507 6.9e-165 ypuA S secreted protein
KIKKMPBN_00508 3.3e-26 L Transposase (IS116 IS110 IS902 family)
KIKKMPBN_00509 4.7e-70 L Transposase (IS116 IS110 IS902 family)
KIKKMPBN_00511 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIKKMPBN_00512 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KIKKMPBN_00513 2.2e-34 nrdH O Glutaredoxin
KIKKMPBN_00514 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KIKKMPBN_00515 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
KIKKMPBN_00516 3.9e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
KIKKMPBN_00517 7.9e-39 ptsH G phosphocarrier protein Hpr
KIKKMPBN_00518 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KIKKMPBN_00519 1.6e-249 L Transposase
KIKKMPBN_00520 3.3e-113 L PFAM Integrase, catalytic core
KIKKMPBN_00521 3.3e-09 L PFAM Integrase, catalytic core
KIKKMPBN_00522 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
KIKKMPBN_00523 8.1e-64 6.3.2.2 H gamma-glutamylcysteine synthetase
KIKKMPBN_00524 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
KIKKMPBN_00526 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
KIKKMPBN_00527 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KIKKMPBN_00529 5.7e-217 S MvaI/BcnI restriction endonuclease family
KIKKMPBN_00531 7.7e-13
KIKKMPBN_00532 5e-31 S Hypothetical protein (DUF2513)
KIKKMPBN_00533 6.5e-31
KIKKMPBN_00534 1e-39
KIKKMPBN_00539 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
KIKKMPBN_00540 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KIKKMPBN_00541 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
KIKKMPBN_00542 5e-30 K Putative DNA-binding domain
KIKKMPBN_00543 3.1e-92 L Transposase, Mutator family
KIKKMPBN_00544 5.6e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KIKKMPBN_00545 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KIKKMPBN_00546 2.5e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
KIKKMPBN_00547 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KIKKMPBN_00548 0.0 uup S abc transporter atp-binding protein
KIKKMPBN_00549 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
KIKKMPBN_00550 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KIKKMPBN_00551 8.7e-150 cobQ S glutamine amidotransferase
KIKKMPBN_00552 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KIKKMPBN_00553 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KIKKMPBN_00554 6e-169 ybbR S Protein conserved in bacteria
KIKKMPBN_00555 1.6e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KIKKMPBN_00556 1.7e-70 gtrA S GtrA-like protein
KIKKMPBN_00557 2.5e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
KIKKMPBN_00558 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KIKKMPBN_00559 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
KIKKMPBN_00560 1.1e-206 yurR 1.4.5.1 E oxidoreductase
KIKKMPBN_00561 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KIKKMPBN_00562 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KIKKMPBN_00563 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KIKKMPBN_00566 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KIKKMPBN_00567 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
KIKKMPBN_00568 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KIKKMPBN_00569 5.3e-121 ylfI S tigr01906
KIKKMPBN_00570 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KIKKMPBN_00571 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KIKKMPBN_00572 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KIKKMPBN_00573 1.3e-22 XK27_08085
KIKKMPBN_00574 5.2e-36 L transposase activity
KIKKMPBN_00575 1.8e-21 L Transposase
KIKKMPBN_00576 1.1e-53 L transposition
KIKKMPBN_00577 1.4e-86 L Integrase core domain protein
KIKKMPBN_00579 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KIKKMPBN_00580 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KIKKMPBN_00581 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KIKKMPBN_00582 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KIKKMPBN_00583 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KIKKMPBN_00584 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KIKKMPBN_00585 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KIKKMPBN_00586 1.9e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KIKKMPBN_00587 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KIKKMPBN_00588 4.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
KIKKMPBN_00589 1.6e-239 rodA D Belongs to the SEDS family
KIKKMPBN_00590 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KIKKMPBN_00591 5.5e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KIKKMPBN_00592 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KIKKMPBN_00593 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KIKKMPBN_00594 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KIKKMPBN_00595 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KIKKMPBN_00596 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KIKKMPBN_00597 2.9e-125 dnaD
KIKKMPBN_00598 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KIKKMPBN_00601 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KIKKMPBN_00602 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
KIKKMPBN_00603 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KIKKMPBN_00604 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KIKKMPBN_00605 1.8e-72 argR K Regulates arginine biosynthesis genes
KIKKMPBN_00606 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
KIKKMPBN_00607 1e-148 DegV S DegV family
KIKKMPBN_00608 3.9e-143 ypmR E lipolytic protein G-D-S-L family
KIKKMPBN_00609 1.7e-83 ypmS S Protein conserved in bacteria
KIKKMPBN_00610 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KIKKMPBN_00612 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KIKKMPBN_00613 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KIKKMPBN_00614 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KIKKMPBN_00615 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KIKKMPBN_00616 2.5e-43 ysdA L Membrane
KIKKMPBN_00617 1.2e-274 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KIKKMPBN_00618 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KIKKMPBN_00619 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
KIKKMPBN_00620 0.0 dnaE 2.7.7.7 L DNA polymerase
KIKKMPBN_00621 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KIKKMPBN_00622 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KIKKMPBN_00623 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
KIKKMPBN_00624 2.7e-26 Q the current gene model (or a revised gene model) may contain a frame shift
KIKKMPBN_00625 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
KIKKMPBN_00627 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
KIKKMPBN_00628 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KIKKMPBN_00629 1.2e-135 XK27_08845 S abc transporter atp-binding protein
KIKKMPBN_00630 1.1e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KIKKMPBN_00631 2e-151 estA CE1 S Putative esterase
KIKKMPBN_00632 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
KIKKMPBN_00633 5.5e-14 XK27_08880
KIKKMPBN_00634 2.3e-75 fld C Flavodoxin
KIKKMPBN_00635 1.3e-282 clcA P Chloride transporter, ClC family
KIKKMPBN_00636 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KIKKMPBN_00637 2.1e-219 XK27_05110 P chloride
KIKKMPBN_00638 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KIKKMPBN_00641 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
KIKKMPBN_00642 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KIKKMPBN_00643 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KIKKMPBN_00644 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIKKMPBN_00645 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KIKKMPBN_00646 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KIKKMPBN_00647 5.9e-26 G Domain of unknown function (DUF4832)
KIKKMPBN_00648 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KIKKMPBN_00650 2.1e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KIKKMPBN_00651 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
KIKKMPBN_00652 7e-124 endA F DNA RNA non-specific endonuclease
KIKKMPBN_00653 1.7e-111 tcyB_2 P ABC transporter (permease)
KIKKMPBN_00654 5.9e-118 gltJ P ABC transporter (Permease
KIKKMPBN_00655 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KIKKMPBN_00656 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
KIKKMPBN_00657 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIKKMPBN_00658 1.5e-247 vicK 2.7.13.3 T Histidine kinase
KIKKMPBN_00659 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KIKKMPBN_00660 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KIKKMPBN_00661 9.2e-147 yidA S hydrolases of the HAD superfamily
KIKKMPBN_00662 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
KIKKMPBN_00663 2.6e-67 ywiB S Domain of unknown function (DUF1934)
KIKKMPBN_00664 0.0 pacL 3.6.3.8 P cation transport ATPase
KIKKMPBN_00665 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KIKKMPBN_00666 4.3e-180 yjjH S Calcineurin-like phosphoesterase
KIKKMPBN_00667 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KIKKMPBN_00668 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KIKKMPBN_00669 2.5e-124 ftsE D cell division ATP-binding protein FtsE
KIKKMPBN_00670 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KIKKMPBN_00671 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KIKKMPBN_00672 4e-175 yubA S permease
KIKKMPBN_00673 3.1e-223 G COG0457 FOG TPR repeat
KIKKMPBN_00674 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KIKKMPBN_00675 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KIKKMPBN_00676 2.9e-90 ebsA S Family of unknown function (DUF5322)
KIKKMPBN_00677 3.9e-15 M LysM domain
KIKKMPBN_00678 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KIKKMPBN_00679 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KIKKMPBN_00680 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KIKKMPBN_00681 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KIKKMPBN_00682 6.8e-23 L Transposase
KIKKMPBN_00683 1.7e-47 XK27_03610 K Gnat family
KIKKMPBN_00684 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KIKKMPBN_00685 2.4e-275 pepV 3.5.1.18 E Dipeptidase
KIKKMPBN_00686 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
KIKKMPBN_00687 1.7e-32 V Glucan-binding protein C
KIKKMPBN_00689 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KIKKMPBN_00690 7.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KIKKMPBN_00691 1.3e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KIKKMPBN_00692 9.9e-119 clcA_2 P chloride
KIKKMPBN_00693 1e-09 yfeJ 6.3.5.2 F glutamine amidotransferase
KIKKMPBN_00694 4e-76 yfeJ 6.3.5.2 F glutamine amidotransferase
KIKKMPBN_00695 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KIKKMPBN_00696 4e-249 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KIKKMPBN_00697 2.5e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KIKKMPBN_00698 1.1e-103 cps4C M biosynthesis protein
KIKKMPBN_00699 9.4e-114 cpsD D COG0489 ATPases involved in chromosome partitioning
KIKKMPBN_00700 1.1e-221 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KIKKMPBN_00701 1.6e-103 rfbP 2.7.8.6 M Bacterial sugar transferase
KIKKMPBN_00702 6.3e-213 rgpAc GT4 M Domain of unknown function (DUF1972)
KIKKMPBN_00703 1.8e-92 lsgC M Glycosyl transferases group 1
KIKKMPBN_00704 8.1e-13 wzy P EpsG family
KIKKMPBN_00705 2.1e-55 M Glycosyltransferase like family 2
KIKKMPBN_00706 2.6e-95 2.7.8.12 GT2 S Glycosyltransferase like family 2
KIKKMPBN_00707 2.4e-46 tnp L DDE domain
KIKKMPBN_00708 8.6e-241 cps1C S Polysaccharide biosynthesis protein
KIKKMPBN_00709 6.4e-94 V VanZ like family
KIKKMPBN_00710 2.3e-13 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KIKKMPBN_00711 6.6e-66 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
KIKKMPBN_00712 8.9e-87 G Belongs to the phosphoglycerate mutase family
KIKKMPBN_00713 1.3e-199 S hmm pf01594
KIKKMPBN_00714 1.8e-98 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KIKKMPBN_00715 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
KIKKMPBN_00716 7.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KIKKMPBN_00717 4.9e-39 S granule-associated protein
KIKKMPBN_00718 1.2e-291 S unusual protein kinase
KIKKMPBN_00719 2.6e-15 estA E Lysophospholipase L1 and related esterases
KIKKMPBN_00720 3.9e-78 estA E GDSL-like protein
KIKKMPBN_00721 1.1e-158 rssA S Phospholipase, patatin family
KIKKMPBN_00722 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KIKKMPBN_00723 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KIKKMPBN_00724 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KIKKMPBN_00725 0.0 S the current gene model (or a revised gene model) may contain a frame shift
KIKKMPBN_00726 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KIKKMPBN_00727 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KIKKMPBN_00728 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KIKKMPBN_00729 0.0 lpdA 1.8.1.4 C Dehydrogenase
KIKKMPBN_00730 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KIKKMPBN_00731 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KIKKMPBN_00732 8.5e-266 3.5.1.28 NU amidase activity
KIKKMPBN_00733 1.9e-37 3.5.1.28 NU amidase activity
KIKKMPBN_00734 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KIKKMPBN_00735 6.1e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KIKKMPBN_00736 1.1e-53 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KIKKMPBN_00737 2e-139 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KIKKMPBN_00738 4e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIKKMPBN_00739 1.9e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KIKKMPBN_00740 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
KIKKMPBN_00741 2.2e-177 fatB P ABC-type enterochelin transport system, periplasmic component
KIKKMPBN_00742 2.1e-152 ycdO P periplasmic lipoprotein involved in iron transport
KIKKMPBN_00743 1.5e-233 ycdB P peroxidase
KIKKMPBN_00744 3e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KIKKMPBN_00745 1.3e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KIKKMPBN_00746 4.6e-25 tatA U protein secretion
KIKKMPBN_00747 2.4e-111 malF P ABC transporter (Permease
KIKKMPBN_00748 1.9e-93 malX G ABC transporter
KIKKMPBN_00749 4.2e-17 malX G ABC transporter
KIKKMPBN_00750 4.2e-27 malR K Transcriptional regulator
KIKKMPBN_00751 2.4e-63 malR K Transcriptional regulator
KIKKMPBN_00752 6.4e-303 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KIKKMPBN_00753 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KIKKMPBN_00754 3.7e-09
KIKKMPBN_00755 1.1e-17
KIKKMPBN_00756 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
KIKKMPBN_00757 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KIKKMPBN_00758 0.0 pepN 3.4.11.2 E aminopeptidase
KIKKMPBN_00759 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
KIKKMPBN_00760 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KIKKMPBN_00761 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KIKKMPBN_00762 1.2e-155 pstA P phosphate transport system permease
KIKKMPBN_00763 3.9e-154 pstC P probably responsible for the translocation of the substrate across the membrane
KIKKMPBN_00764 3.3e-158 pstS P phosphate
KIKKMPBN_00765 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KIKKMPBN_00766 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KIKKMPBN_00767 1.9e-43 yktA S Belongs to the UPF0223 family
KIKKMPBN_00768 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KIKKMPBN_00769 2.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KIKKMPBN_00770 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KIKKMPBN_00771 3.6e-136 XK27_04775 S hemerythrin HHE cation binding domain
KIKKMPBN_00772 3.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KIKKMPBN_00773 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KIKKMPBN_00774 9.3e-62 S haloacid dehalogenase-like hydrolase
KIKKMPBN_00775 1.8e-59 Q phosphatase activity
KIKKMPBN_00776 1.7e-240 metY 2.5.1.49 E o-acetylhomoserine
KIKKMPBN_00777 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KIKKMPBN_00778 1.8e-240 agcS E (Alanine) symporter
KIKKMPBN_00779 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KIKKMPBN_00780 3.2e-35 yfiF3 K sequence-specific DNA binding
KIKKMPBN_00781 1.9e-13 yfiF3 K sequence-specific DNA binding
KIKKMPBN_00782 3.7e-60 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KIKKMPBN_00783 1.8e-113 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KIKKMPBN_00785 3.5e-68 yecS P ABC transporter (Permease
KIKKMPBN_00786 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
KIKKMPBN_00787 5e-103 nylA 3.5.1.4 J Belongs to the amidase family
KIKKMPBN_00788 1.1e-267 dtpT E transporter
KIKKMPBN_00790 3.6e-63 nylA 3.5.1.4 J Belongs to the amidase family
KIKKMPBN_00791 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KIKKMPBN_00792 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KIKKMPBN_00793 5.2e-74 csm6 S Psort location Cytoplasmic, score
KIKKMPBN_00794 2.1e-14 csm6 S Psort location Cytoplasmic, score
KIKKMPBN_00795 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
KIKKMPBN_00796 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
KIKKMPBN_00797 1.1e-116 csm3 L RAMP superfamily
KIKKMPBN_00798 5.6e-62 csm2 L Pfam:DUF310
KIKKMPBN_00799 0.0 csm1 S CRISPR-associated protein Csm1 family
KIKKMPBN_00800 6.8e-133 cas6 S Pfam:DUF2276
KIKKMPBN_00801 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIKKMPBN_00802 1.2e-180 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIKKMPBN_00803 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KIKKMPBN_00804 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KIKKMPBN_00805 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KIKKMPBN_00806 5.7e-118 S TraX protein
KIKKMPBN_00808 3.5e-28 3.4.13.21 I Protein conserved in bacteria
KIKKMPBN_00809 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
KIKKMPBN_00810 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KIKKMPBN_00811 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KIKKMPBN_00812 1.7e-35 XK27_09805 S MORN repeat protein
KIKKMPBN_00813 0.0 XK27_09800 I Acyltransferase
KIKKMPBN_00814 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KIKKMPBN_00815 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KIKKMPBN_00816 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KIKKMPBN_00817 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
KIKKMPBN_00818 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KIKKMPBN_00819 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KIKKMPBN_00820 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KIKKMPBN_00821 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KIKKMPBN_00822 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KIKKMPBN_00823 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KIKKMPBN_00824 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KIKKMPBN_00825 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KIKKMPBN_00826 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KIKKMPBN_00827 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KIKKMPBN_00828 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KIKKMPBN_00829 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KIKKMPBN_00830 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KIKKMPBN_00831 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KIKKMPBN_00832 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KIKKMPBN_00833 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KIKKMPBN_00834 2.5e-23 rpmD J ribosomal protein l30
KIKKMPBN_00835 4.4e-58 rplO J binds to the 23S rRNA
KIKKMPBN_00836 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KIKKMPBN_00837 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KIKKMPBN_00838 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KIKKMPBN_00839 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KIKKMPBN_00840 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KIKKMPBN_00841 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KIKKMPBN_00842 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIKKMPBN_00843 3.3e-62 rplQ J ribosomal protein l17
KIKKMPBN_00844 8.3e-93 L PFAM Integrase, catalytic core
KIKKMPBN_00845 2e-35 L PFAM Integrase, catalytic core
KIKKMPBN_00848 3.3e-95 ywlG S Belongs to the UPF0340 family
KIKKMPBN_00849 1.2e-85 treR K trehalose operon
KIKKMPBN_00850 5.8e-21 treR K DNA-binding transcription factor activity
KIKKMPBN_00851 1.4e-54 treB 2.7.1.201 G PTS System
KIKKMPBN_00852 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KIKKMPBN_00853 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KIKKMPBN_00854 1.8e-37 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KIKKMPBN_00855 0.0 pepO 3.4.24.71 O Peptidase family M13
KIKKMPBN_00856 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
KIKKMPBN_00857 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KIKKMPBN_00858 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KIKKMPBN_00859 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
KIKKMPBN_00860 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KIKKMPBN_00861 2.4e-278 thrC 4.2.3.1 E Threonine synthase
KIKKMPBN_00862 9.3e-226 norN V Mate efflux family protein
KIKKMPBN_00863 1.4e-57 asp S cog cog1302
KIKKMPBN_00864 6.4e-304 yloV S kinase related to dihydroxyacetone kinase
KIKKMPBN_00865 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KIKKMPBN_00866 2.6e-277 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KIKKMPBN_00867 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KIKKMPBN_00868 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
KIKKMPBN_00869 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KIKKMPBN_00870 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KIKKMPBN_00871 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KIKKMPBN_00872 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIKKMPBN_00873 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KIKKMPBN_00874 2.9e-68 S cog cog4699
KIKKMPBN_00875 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KIKKMPBN_00876 5.6e-52 cglB NU type II secretion system
KIKKMPBN_00877 1.1e-87 cglB NU type II secretion system
KIKKMPBN_00878 8.5e-43 comGC U Required for transformation and DNA binding
KIKKMPBN_00879 1.8e-57 cglD NU Competence protein
KIKKMPBN_00880 1.4e-15 NU Type II secretory pathway pseudopilin
KIKKMPBN_00881 1.7e-70 comGF U Competence protein ComGF
KIKKMPBN_00882 3.7e-190
KIKKMPBN_00883 2.3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KIKKMPBN_00885 4.8e-41 dinF V Mate efflux family protein
KIKKMPBN_00886 6.6e-73 dinF V Mate efflux family protein
KIKKMPBN_00887 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
KIKKMPBN_00888 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
KIKKMPBN_00889 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KIKKMPBN_00890 2.6e-143 2.4.2.3 F Phosphorylase superfamily
KIKKMPBN_00893 3.8e-78 S Alpha/beta hydrolase of unknown function (DUF915)
KIKKMPBN_00894 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
KIKKMPBN_00895 6e-08 S Hydrolases of the alpha beta superfamily
KIKKMPBN_00896 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KIKKMPBN_00897 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KIKKMPBN_00898 1.8e-159 czcD P cation diffusion facilitator family transporter
KIKKMPBN_00899 9e-98 K Transcriptional regulator, TetR family
KIKKMPBN_00900 1.6e-10
KIKKMPBN_00901 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KIKKMPBN_00902 3e-14 V ABC transporter (Permease
KIKKMPBN_00903 4.1e-88 V ABC transporter (Permease
KIKKMPBN_00904 9.6e-13
KIKKMPBN_00905 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KIKKMPBN_00906 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KIKKMPBN_00907 8.6e-61 EGP Major facilitator Superfamily
KIKKMPBN_00908 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
KIKKMPBN_00909 7.2e-212 pqqE C radical SAM domain protein
KIKKMPBN_00912 6.7e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KIKKMPBN_00913 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KIKKMPBN_00914 3.9e-19 IQ Acetoin reductase
KIKKMPBN_00915 2.2e-49 IQ Acetoin reductase
KIKKMPBN_00916 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KIKKMPBN_00917 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KIKKMPBN_00918 7.5e-21 XK27_05470 E Methionine synthase
KIKKMPBN_00919 2.7e-151 XK27_05470 E Methionine synthase
KIKKMPBN_00920 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KIKKMPBN_00921 4.3e-253 T PhoQ Sensor
KIKKMPBN_00922 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIKKMPBN_00923 5.1e-153 S TraX protein
KIKKMPBN_00924 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KIKKMPBN_00925 8.3e-159 dprA LU DNA protecting protein DprA
KIKKMPBN_00926 1.6e-166 GK ROK family
KIKKMPBN_00927 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIKKMPBN_00928 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KIKKMPBN_00929 8.1e-128 K DNA-binding helix-turn-helix protein
KIKKMPBN_00930 3e-90 niaR S small molecule binding protein (contains 3H domain)
KIKKMPBN_00931 3.1e-87 niaX
KIKKMPBN_00932 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KIKKMPBN_00933 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KIKKMPBN_00934 2e-126 gntR1 K transcriptional
KIKKMPBN_00935 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KIKKMPBN_00936 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KIKKMPBN_00937 0.0 res_1 3.1.21.5 S Type III restriction
KIKKMPBN_00938 1.1e-20
KIKKMPBN_00940 7.4e-110 adhP 1.1.1.1 C alcohol dehydrogenase
KIKKMPBN_00941 2.3e-62 adhP 1.1.1.1 C alcohol dehydrogenase
KIKKMPBN_00942 2.1e-07
KIKKMPBN_00943 7.3e-110 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIKKMPBN_00944 2.4e-72 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KIKKMPBN_00945 2.1e-157 aatB ET ABC transporter substrate-binding protein
KIKKMPBN_00946 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
KIKKMPBN_00947 2.6e-104 artQ P ABC transporter (Permease
KIKKMPBN_00948 7.3e-58 phnA P Alkylphosphonate utilization operon protein PhnA
KIKKMPBN_00949 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KIKKMPBN_00950 4.5e-166 cpsY K Transcriptional regulator
KIKKMPBN_00951 1.6e-19 L transposase activity
KIKKMPBN_00952 1.6e-118 mur1 NU muramidase
KIKKMPBN_00953 1e-171 yeiH S Membrane
KIKKMPBN_00954 1.7e-08
KIKKMPBN_00955 4.7e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
KIKKMPBN_00956 3.8e-85 XK27_10720 D peptidase activity
KIKKMPBN_00957 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
KIKKMPBN_00958 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
KIKKMPBN_00959 7e-156 glcU U Glucose uptake
KIKKMPBN_00960 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
KIKKMPBN_00961 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
KIKKMPBN_00962 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
KIKKMPBN_00963 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KIKKMPBN_00964 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KIKKMPBN_00965 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KIKKMPBN_00966 0.0 copB 3.6.3.4 P P-type ATPase
KIKKMPBN_00967 5.6e-08 comGF U Putative Competence protein ComGF
KIKKMPBN_00968 5.9e-177 ytxK 2.1.1.72 L DNA methylase
KIKKMPBN_00969 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KIKKMPBN_00970 8.8e-27 lanR K sequence-specific DNA binding
KIKKMPBN_00971 5e-67 V CAAX protease self-immunity
KIKKMPBN_00973 3.9e-111 S CAAX amino terminal protease family protein
KIKKMPBN_00974 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KIKKMPBN_00975 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KIKKMPBN_00976 4.1e-09 S Domain of unknown function (DUF4651)
KIKKMPBN_00977 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KIKKMPBN_00978 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KIKKMPBN_00979 1.8e-187 yeeE S Sulphur transport
KIKKMPBN_00980 6.4e-37 yeeD O sulfur carrier activity
KIKKMPBN_00981 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KIKKMPBN_00982 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KIKKMPBN_00984 2e-157 rrmA 2.1.1.187 Q methyltransferase
KIKKMPBN_00985 3.4e-64 S phosphatase activity
KIKKMPBN_00986 2.7e-48 S glycolate biosynthetic process
KIKKMPBN_00987 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KIKKMPBN_00988 1.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KIKKMPBN_00989 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KIKKMPBN_00990 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KIKKMPBN_00991 9.4e-43 K Cold-Shock Protein
KIKKMPBN_00992 7.4e-32 cspD K Cold shock protein domain
KIKKMPBN_00993 3.7e-40 pepD E dipeptidase activity
KIKKMPBN_00994 8e-90 pepD E Dipeptidase
KIKKMPBN_00995 8.7e-162 whiA K May be required for sporulation
KIKKMPBN_00996 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KIKKMPBN_00997 1.2e-163 rapZ S Displays ATPase and GTPase activities
KIKKMPBN_00998 2e-135 yejC S cyclic nucleotide-binding protein
KIKKMPBN_00999 2.2e-19 D nuclear chromosome segregation
KIKKMPBN_01000 1.9e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KIKKMPBN_01001 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KIKKMPBN_01002 5.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
KIKKMPBN_01003 9.8e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KIKKMPBN_01004 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KIKKMPBN_01005 6.8e-54 L Transposase
KIKKMPBN_01006 2.5e-15
KIKKMPBN_01007 4.2e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KIKKMPBN_01008 1.6e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KIKKMPBN_01009 6.8e-81 ypmB S Protein conserved in bacteria
KIKKMPBN_01010 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KIKKMPBN_01011 1.2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KIKKMPBN_01012 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KIKKMPBN_01013 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
KIKKMPBN_01014 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KIKKMPBN_01015 3.6e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KIKKMPBN_01016 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KIKKMPBN_01017 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KIKKMPBN_01018 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KIKKMPBN_01019 8.6e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KIKKMPBN_01020 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KIKKMPBN_01021 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
KIKKMPBN_01022 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
KIKKMPBN_01023 2.1e-30 rpsT J rRNA binding
KIKKMPBN_01024 1.2e-165 L integrase core domain
KIKKMPBN_01025 1.1e-121 L Transposase
KIKKMPBN_01026 8.3e-78 T PhoQ Sensor
KIKKMPBN_01027 1.7e-43 T PhoQ Sensor
KIKKMPBN_01028 2.8e-40 T PhoQ Sensor
KIKKMPBN_01029 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIKKMPBN_01030 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KIKKMPBN_01031 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KIKKMPBN_01032 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KIKKMPBN_01033 1.4e-93 panT S ECF transporter, substrate-specific component
KIKKMPBN_01034 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KIKKMPBN_01035 7.3e-166 metF 1.5.1.20 E reductase
KIKKMPBN_01036 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KIKKMPBN_01038 3.8e-218 sip L Belongs to the 'phage' integrase family
KIKKMPBN_01039 1e-21 xre K transcriptional
KIKKMPBN_01040 1.8e-19 K Cro/C1-type HTH DNA-binding domain
KIKKMPBN_01044 1.4e-13
KIKKMPBN_01045 9e-22
KIKKMPBN_01046 1.8e-132 KL Phage plasmid primase P4 family
KIKKMPBN_01047 2.8e-66 S Virulence-associated protein E
KIKKMPBN_01049 5.9e-13
KIKKMPBN_01052 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KIKKMPBN_01053 0.0 3.6.3.8 P cation transport ATPase
KIKKMPBN_01054 7.7e-19 L transposase activity
KIKKMPBN_01055 6.5e-54 L transposition
KIKKMPBN_01056 9.6e-32 L transposition
KIKKMPBN_01057 9.8e-32 L Integrase core domain protein
KIKKMPBN_01058 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KIKKMPBN_01059 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIKKMPBN_01060 4.6e-238 dltB M Membrane protein involved in D-alanine export
KIKKMPBN_01061 1.6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIKKMPBN_01062 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
KIKKMPBN_01063 0.0 XK27_10035 V abc transporter atp-binding protein
KIKKMPBN_01064 0.0 yfiB1 V abc transporter atp-binding protein
KIKKMPBN_01065 8e-100 pvaA M lytic transglycosylase activity
KIKKMPBN_01066 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
KIKKMPBN_01067 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KIKKMPBN_01068 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KIKKMPBN_01069 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KIKKMPBN_01070 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KIKKMPBN_01071 4.5e-111 tdk 2.7.1.21 F thymidine kinase
KIKKMPBN_01072 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KIKKMPBN_01073 8.9e-155 gst O Glutathione S-transferase
KIKKMPBN_01074 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KIKKMPBN_01075 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KIKKMPBN_01076 2e-45 rpmE2 J 50S ribosomal protein L31
KIKKMPBN_01077 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
KIKKMPBN_01078 8.4e-10
KIKKMPBN_01079 5.5e-30
KIKKMPBN_01080 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KIKKMPBN_01081 1.8e-135 divIVA D Cell division protein DivIVA
KIKKMPBN_01082 4e-142 ylmH T S4 RNA-binding domain
KIKKMPBN_01083 4.4e-34 yggT D integral membrane protein
KIKKMPBN_01084 2e-87 sepF D cell septum assembly
KIKKMPBN_01085 6.6e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KIKKMPBN_01086 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KIKKMPBN_01087 4.4e-250 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KIKKMPBN_01088 8.2e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KIKKMPBN_01089 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KIKKMPBN_01090 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KIKKMPBN_01092 0.0 typA T GTP-binding protein TypA
KIKKMPBN_01093 2.2e-179 glk 2.7.1.2 G Glucokinase
KIKKMPBN_01094 8.4e-28 yqgQ S protein conserved in bacteria
KIKKMPBN_01095 1.2e-79 perR P Belongs to the Fur family
KIKKMPBN_01096 3.5e-91 dps P Belongs to the Dps family
KIKKMPBN_01097 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KIKKMPBN_01098 2.6e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KIKKMPBN_01099 1.9e-23 L Transposase
KIKKMPBN_01100 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KIKKMPBN_01101 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
KIKKMPBN_01102 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KIKKMPBN_01103 6.2e-56 S Domain of unknown function (DUF4430)
KIKKMPBN_01104 5.1e-73 S Psort location CytoplasmicMembrane, score
KIKKMPBN_01105 1.8e-135 htpX O Belongs to the peptidase M48B family
KIKKMPBN_01106 1.5e-92 lemA S LemA family
KIKKMPBN_01107 8.8e-157 spd F DNA RNA non-specific endonuclease
KIKKMPBN_01108 3e-38
KIKKMPBN_01109 2.5e-44
KIKKMPBN_01111 9.3e-68 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
KIKKMPBN_01112 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
KIKKMPBN_01113 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
KIKKMPBN_01114 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
KIKKMPBN_01115 1.6e-22 MA20_36090 S Protein of unknown function (DUF2974)
KIKKMPBN_01116 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KIKKMPBN_01117 2.1e-27 P Hemerythrin HHE cation binding domain protein
KIKKMPBN_01118 4.5e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
KIKKMPBN_01119 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KIKKMPBN_01120 9.6e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
KIKKMPBN_01121 1.1e-10 S hydrolase
KIKKMPBN_01122 4.2e-152 S hydrolase
KIKKMPBN_01123 3.1e-20
KIKKMPBN_01125 2.8e-42 M LysM domain
KIKKMPBN_01126 5e-16 M LysM domain
KIKKMPBN_01127 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KIKKMPBN_01128 8.2e-35
KIKKMPBN_01130 3.2e-167 S Domain of unknown function DUF87
KIKKMPBN_01131 2.1e-167 S SIR2-like domain
KIKKMPBN_01132 1.5e-28 S SIR2-like domain
KIKKMPBN_01133 4.1e-225 mutH L DNA mismatch repair enzyme MutH
KIKKMPBN_01134 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KIKKMPBN_01135 4.3e-12
KIKKMPBN_01136 5.1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
KIKKMPBN_01137 1.1e-33 XK27_12190 S protein conserved in bacteria
KIKKMPBN_01139 8.4e-88 bioY S biotin synthase
KIKKMPBN_01140 8.1e-46 S CHY zinc finger
KIKKMPBN_01141 3.4e-252 yegQ O Peptidase U32
KIKKMPBN_01142 2e-177 yegQ O Peptidase U32
KIKKMPBN_01144 5.5e-69 ytxH S General stress protein
KIKKMPBN_01146 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KIKKMPBN_01147 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KIKKMPBN_01148 9.9e-42 pspC KT PspC domain
KIKKMPBN_01149 0.0 yhgF K Transcriptional accessory protein
KIKKMPBN_01151 7.1e-156 XK27_03015 S permease
KIKKMPBN_01152 7.8e-146 ycgQ S TIGR03943 family
KIKKMPBN_01153 2.6e-194 S CRISPR-associated protein Csn2 subfamily St
KIKKMPBN_01154 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIKKMPBN_01155 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KIKKMPBN_01156 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KIKKMPBN_01157 1.4e-94
KIKKMPBN_01158 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
KIKKMPBN_01159 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
KIKKMPBN_01160 1e-31 K Cro/C1-type HTH DNA-binding domain
KIKKMPBN_01161 3.2e-46
KIKKMPBN_01162 8.9e-20
KIKKMPBN_01163 1.1e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIKKMPBN_01164 4.5e-97 mip S hydroperoxide reductase activity
KIKKMPBN_01165 2.4e-203 I acyl-CoA dehydrogenase
KIKKMPBN_01166 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
KIKKMPBN_01167 6.4e-252 msrR K Transcriptional regulator
KIKKMPBN_01168 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
KIKKMPBN_01169 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KIKKMPBN_01170 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KIKKMPBN_01171 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KIKKMPBN_01172 3.2e-53 yheA S Belongs to the UPF0342 family
KIKKMPBN_01173 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KIKKMPBN_01174 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KIKKMPBN_01175 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KIKKMPBN_01176 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KIKKMPBN_01177 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KIKKMPBN_01178 2e-219 ywbD 2.1.1.191 J Methyltransferase
KIKKMPBN_01179 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KIKKMPBN_01180 2e-25 WQ51_00785
KIKKMPBN_01181 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KIKKMPBN_01182 1e-78 yueI S Protein of unknown function (DUF1694)
KIKKMPBN_01183 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KIKKMPBN_01184 6.6e-101 yyaQ V Protein conserved in bacteria
KIKKMPBN_01185 2.8e-28 yyaQ S YjbR
KIKKMPBN_01186 4.4e-183 ccpA K Catabolite control protein A
KIKKMPBN_01187 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KIKKMPBN_01188 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KIKKMPBN_01189 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KIKKMPBN_01190 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KIKKMPBN_01191 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KIKKMPBN_01192 2.9e-32 secG U Preprotein translocase subunit SecG
KIKKMPBN_01193 3.6e-219 mdtG EGP Major facilitator Superfamily
KIKKMPBN_01194 1.4e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KIKKMPBN_01195 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KIKKMPBN_01196 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KIKKMPBN_01197 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KIKKMPBN_01198 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KIKKMPBN_01199 6.8e-53 licT K transcriptional antiterminator
KIKKMPBN_01200 5.8e-64 licT K transcriptional antiterminator
KIKKMPBN_01201 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KIKKMPBN_01202 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KIKKMPBN_01203 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KIKKMPBN_01204 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KIKKMPBN_01205 7.5e-23 I Alpha/beta hydrolase family
KIKKMPBN_01206 1.5e-35 yugF I carboxylic ester hydrolase activity
KIKKMPBN_01207 2.2e-45 K sequence-specific DNA binding
KIKKMPBN_01208 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KIKKMPBN_01209 1.5e-07
KIKKMPBN_01210 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KIKKMPBN_01211 1.1e-78 feoA P FeoA domain protein
KIKKMPBN_01212 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
KIKKMPBN_01213 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KIKKMPBN_01214 1.3e-34 ykuJ S protein conserved in bacteria
KIKKMPBN_01215 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KIKKMPBN_01216 0.0 clpE O Belongs to the ClpA ClpB family
KIKKMPBN_01217 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KIKKMPBN_01218 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
KIKKMPBN_01219 9.7e-66 S oxidoreductase
KIKKMPBN_01220 9.3e-59 S oxidoreductase
KIKKMPBN_01221 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
KIKKMPBN_01222 6.1e-70 M Pfam SNARE associated Golgi protein
KIKKMPBN_01223 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
KIKKMPBN_01226 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
KIKKMPBN_01229 4.8e-16 S Protein of unknown function (DUF2969)
KIKKMPBN_01230 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
KIKKMPBN_01231 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIKKMPBN_01232 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KIKKMPBN_01233 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KIKKMPBN_01234 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
KIKKMPBN_01235 1.4e-29 S Domain of unknown function (DUF1912)
KIKKMPBN_01236 4.5e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KIKKMPBN_01237 2.2e-249 mmuP E amino acid
KIKKMPBN_01238 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KIKKMPBN_01239 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KIKKMPBN_01240 9.7e-22
KIKKMPBN_01241 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KIKKMPBN_01242 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KIKKMPBN_01243 1.7e-218 mvaS 2.3.3.10 I synthase
KIKKMPBN_01244 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KIKKMPBN_01245 1e-25 K hmm pf08876
KIKKMPBN_01246 1.5e-118 yqfA K protein, Hemolysin III
KIKKMPBN_01247 1.2e-22 S Protein of unknown function (DUF3114)
KIKKMPBN_01248 9.8e-163 S Protein of unknown function (DUF3114)
KIKKMPBN_01249 9.9e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KIKKMPBN_01250 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KIKKMPBN_01251 4.9e-21 XK27_13030
KIKKMPBN_01252 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KIKKMPBN_01253 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KIKKMPBN_01254 1.1e-11 U protein secretion
KIKKMPBN_01255 2.1e-50 U protein secretion
KIKKMPBN_01256 3.5e-07 U protein secretion
KIKKMPBN_01258 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KIKKMPBN_01259 2.5e-21
KIKKMPBN_01260 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KIKKMPBN_01261 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KIKKMPBN_01262 3.4e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KIKKMPBN_01263 5e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
KIKKMPBN_01264 1.3e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KIKKMPBN_01265 1.8e-140 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KIKKMPBN_01266 6.1e-105 GBS0088 J protein conserved in bacteria
KIKKMPBN_01267 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KIKKMPBN_01268 5.9e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KIKKMPBN_01269 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
KIKKMPBN_01270 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIKKMPBN_01271 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KIKKMPBN_01272 9.6e-113 S VIT family
KIKKMPBN_01273 1.8e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
KIKKMPBN_01274 1.9e-22
KIKKMPBN_01275 8e-28 XK27_00085 K Transcriptional
KIKKMPBN_01276 6.9e-197 yceA S Belongs to the UPF0176 family
KIKKMPBN_01277 5.4e-122 sagI S ABC-2 type transporter
KIKKMPBN_01278 2.8e-168 V ABC transporter
KIKKMPBN_01279 2.5e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KIKKMPBN_01280 2.5e-132 rr02 KT response regulator
KIKKMPBN_01281 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KIKKMPBN_01282 2.6e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KIKKMPBN_01283 6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KIKKMPBN_01284 0.0 lmrA V abc transporter atp-binding protein
KIKKMPBN_01285 0.0 mdlB V abc transporter atp-binding protein
KIKKMPBN_01287 0.0 M domain protein
KIKKMPBN_01288 5.9e-51 M YSIRK type signal peptide
KIKKMPBN_01289 8.8e-92 S MucBP domain
KIKKMPBN_01292 1.6e-18 L Integrase core domain
KIKKMPBN_01293 8e-112 L Transposase
KIKKMPBN_01294 5.9e-109 L Transposase
KIKKMPBN_01295 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KIKKMPBN_01296 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KIKKMPBN_01297 1.1e-24 ytrF V efflux transmembrane transporter activity
KIKKMPBN_01298 1.2e-35 V efflux transmembrane transporter activity
KIKKMPBN_01299 3.6e-35 V efflux transmembrane transporter activity
KIKKMPBN_01300 4.4e-30 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KIKKMPBN_01301 1.4e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
KIKKMPBN_01302 5.1e-14 L Transposase
KIKKMPBN_01303 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KIKKMPBN_01304 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KIKKMPBN_01305 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KIKKMPBN_01306 4.9e-227 pyrP F uracil Permease
KIKKMPBN_01307 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KIKKMPBN_01308 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KIKKMPBN_01309 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KIKKMPBN_01310 1.4e-167 fhuR K transcriptional regulator (lysR family)
KIKKMPBN_01315 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KIKKMPBN_01316 9.7e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
KIKKMPBN_01317 2.5e-119 pts33BCA G pts system
KIKKMPBN_01318 1.7e-70 pts33BCA G pts system
KIKKMPBN_01319 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
KIKKMPBN_01320 1.8e-254 cycA E permease
KIKKMPBN_01321 4.5e-39 ynzC S UPF0291 protein
KIKKMPBN_01322 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KIKKMPBN_01323 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KIKKMPBN_01324 6.1e-63 S membrane
KIKKMPBN_01325 1.5e-59
KIKKMPBN_01326 7.5e-26
KIKKMPBN_01327 1.8e-53
KIKKMPBN_01328 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KIKKMPBN_01329 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
KIKKMPBN_01330 2.2e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KIKKMPBN_01331 3.2e-105 mur1 NU mannosyl-glycoprotein
KIKKMPBN_01332 6.6e-54 glnB K Belongs to the P(II) protein family
KIKKMPBN_01333 5.8e-233 amt P Ammonium Transporter
KIKKMPBN_01334 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KIKKMPBN_01335 9.5e-55 yabA L Involved in initiation control of chromosome replication
KIKKMPBN_01336 1.2e-135 yaaT S stage 0 sporulation protein
KIKKMPBN_01337 6.4e-162 holB 2.7.7.7 L dna polymerase iii
KIKKMPBN_01338 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KIKKMPBN_01339 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KIKKMPBN_01340 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KIKKMPBN_01341 2.8e-230 ftsW D Belongs to the SEDS family
KIKKMPBN_01342 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KIKKMPBN_01343 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KIKKMPBN_01344 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KIKKMPBN_01345 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KIKKMPBN_01346 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIKKMPBN_01347 3.3e-78 atpF C ATP synthase F(0) sector subunit b
KIKKMPBN_01348 3.1e-122 atpB C it plays a direct role in the translocation of protons across the membrane
KIKKMPBN_01349 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KIKKMPBN_01350 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KIKKMPBN_01351 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KIKKMPBN_01352 1.1e-89 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KIKKMPBN_01353 8.9e-14 coiA 3.6.4.12 S Competence protein
KIKKMPBN_01354 2.2e-15 T peptidase
KIKKMPBN_01355 3e-151 rarD S Transporter
KIKKMPBN_01356 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KIKKMPBN_01357 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KIKKMPBN_01358 2.1e-128 yxkH G deacetylase
KIKKMPBN_01359 1.2e-208 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KIKKMPBN_01360 1.3e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KIKKMPBN_01361 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KIKKMPBN_01362 1.7e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KIKKMPBN_01363 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KIKKMPBN_01364 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KIKKMPBN_01365 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
KIKKMPBN_01366 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
KIKKMPBN_01367 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KIKKMPBN_01368 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KIKKMPBN_01369 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KIKKMPBN_01370 1.1e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KIKKMPBN_01371 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
KIKKMPBN_01372 0.0 pepF E oligoendopeptidase F
KIKKMPBN_01373 1.4e-186 coiA 3.6.4.12 S Competence protein
KIKKMPBN_01374 1.8e-164 K transcriptional regulator (lysR family)
KIKKMPBN_01375 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KIKKMPBN_01379 1e-190 phoH T phosphate starvation-inducible protein PhoH
KIKKMPBN_01380 8.7e-120 sip M LysM domain protein
KIKKMPBN_01381 7.4e-35 yozE S Belongs to the UPF0346 family
KIKKMPBN_01382 5.3e-161 cvfB S Protein conserved in bacteria
KIKKMPBN_01383 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KIKKMPBN_01384 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KIKKMPBN_01385 4.5e-77 sptS 2.7.13.3 T Histidine kinase
KIKKMPBN_01386 7.1e-37 K Acetyltransferase (GNAT) family
KIKKMPBN_01387 0.0 lmrA2 V abc transporter atp-binding protein
KIKKMPBN_01388 0.0 lmrA1 V abc transporter atp-binding protein
KIKKMPBN_01389 1.9e-77 K DNA-binding transcription factor activity
KIKKMPBN_01390 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KIKKMPBN_01391 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KIKKMPBN_01392 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KIKKMPBN_01393 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KIKKMPBN_01394 1.6e-24 U response to pH
KIKKMPBN_01395 0.0 yfmR S abc transporter atp-binding protein
KIKKMPBN_01396 1.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KIKKMPBN_01397 1.9e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KIKKMPBN_01398 3.6e-74 XK27_08360 S EDD domain protein, DegV family
KIKKMPBN_01399 1.9e-60 XK27_08360 S EDD domain protein, DegV family
KIKKMPBN_01400 2.3e-60 WQ51_03320 S cog cog4835
KIKKMPBN_01401 3e-122 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KIKKMPBN_01402 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KIKKMPBN_01403 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
KIKKMPBN_01404 6.4e-29 2.3.1.128 K acetyltransferase
KIKKMPBN_01405 4.9e-39 2.3.1.128 K acetyltransferase
KIKKMPBN_01406 3e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KIKKMPBN_01407 1.4e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KIKKMPBN_01408 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KIKKMPBN_01409 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KIKKMPBN_01411 3.4e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KIKKMPBN_01412 3.2e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KIKKMPBN_01413 2.7e-102 fruA 2.7.1.202 G phosphotransferase system
KIKKMPBN_01414 2.3e-25 fruA 2.7.1.202 G phosphotransferase system
KIKKMPBN_01415 7.8e-22 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
KIKKMPBN_01416 1.6e-78 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
KIKKMPBN_01417 4.6e-163 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KIKKMPBN_01418 2.1e-113 fruR K transcriptional
KIKKMPBN_01419 1.8e-84 L Transposase
KIKKMPBN_01420 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KIKKMPBN_01421 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KIKKMPBN_01422 2.2e-27 XK27_08585 S Psort location CytoplasmicMembrane, score
KIKKMPBN_01423 1.2e-23 XK27_08585 S Psort location CytoplasmicMembrane, score
KIKKMPBN_01424 5.7e-35 fnt P Formate nitrite transporter
KIKKMPBN_01425 7.9e-72 fnt P Formate nitrite transporter
KIKKMPBN_01426 4.4e-140 XK27_09615 C reductase
KIKKMPBN_01427 9e-62 XK27_09615 C reductase
KIKKMPBN_01428 4.3e-77 XK27_09620 S reductase
KIKKMPBN_01429 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
KIKKMPBN_01430 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KIKKMPBN_01431 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KIKKMPBN_01432 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
KIKKMPBN_01433 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
KIKKMPBN_01434 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KIKKMPBN_01435 3.5e-50 S Protein of unknown function (DUF3397)
KIKKMPBN_01436 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KIKKMPBN_01437 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KIKKMPBN_01438 4.2e-74 amiA E transmembrane transport
KIKKMPBN_01439 2.2e-79 amiA E transmembrane transport
KIKKMPBN_01440 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KIKKMPBN_01441 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KIKKMPBN_01442 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
KIKKMPBN_01443 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KIKKMPBN_01444 1.7e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KIKKMPBN_01445 5.5e-184 jag S RNA-binding protein
KIKKMPBN_01446 1e-13 rpmH J Ribosomal protein L34
KIKKMPBN_01447 5e-84 L Transposase
KIKKMPBN_01448 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KIKKMPBN_01450 2.5e-204 rny D Endoribonuclease that initiates mRNA decay
KIKKMPBN_01451 6.6e-38 L transposase activity
KIKKMPBN_01452 8.4e-155 L COG2801 Transposase and inactivated derivatives
KIKKMPBN_01453 1.1e-113 K sequence-specific DNA binding
KIKKMPBN_01454 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
KIKKMPBN_01455 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
KIKKMPBN_01456 7.7e-198 V (ABC) transporter
KIKKMPBN_01457 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
KIKKMPBN_01458 8e-277 S Protein of unknown function (DUF3114)
KIKKMPBN_01460 3.4e-35 tnp L Transposase
KIKKMPBN_01461 1.3e-07 L Transposase and inactivated derivatives, TnpA family
KIKKMPBN_01462 4.4e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
KIKKMPBN_01463 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
KIKKMPBN_01464 1.1e-65 tnp L Transposase
KIKKMPBN_01465 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KIKKMPBN_01466 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KIKKMPBN_01467 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KIKKMPBN_01468 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KIKKMPBN_01469 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KIKKMPBN_01470 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KIKKMPBN_01471 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KIKKMPBN_01472 1.6e-126 IQ reductase
KIKKMPBN_01473 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KIKKMPBN_01474 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KIKKMPBN_01475 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIKKMPBN_01476 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KIKKMPBN_01477 4e-72 marR K Transcriptional regulator, MarR family
KIKKMPBN_01478 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KIKKMPBN_01479 1.9e-115 S Haloacid dehalogenase-like hydrolase
KIKKMPBN_01480 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
KIKKMPBN_01481 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
KIKKMPBN_01482 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KIKKMPBN_01483 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
KIKKMPBN_01484 7.8e-102 ygaC J Belongs to the UPF0374 family
KIKKMPBN_01485 6.4e-108 S Domain of unknown function (DUF1803)
KIKKMPBN_01486 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
KIKKMPBN_01494 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KIKKMPBN_01495 1.7e-122 comFC S Competence protein
KIKKMPBN_01496 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KIKKMPBN_01497 1.1e-110 yvyE 3.4.13.9 S YigZ family
KIKKMPBN_01498 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KIKKMPBN_01499 8.9e-41 acuB S IMP dehydrogenase activity
KIKKMPBN_01500 6.8e-69 acuB S IMP dehydrogenase activity
KIKKMPBN_01501 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KIKKMPBN_01502 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KIKKMPBN_01503 1.6e-137 livM E Belongs to the binding-protein-dependent transport system permease family
KIKKMPBN_01504 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KIKKMPBN_01505 1.8e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KIKKMPBN_01506 7.1e-46 ylbG S UPF0298 protein
KIKKMPBN_01507 1.2e-74 ylbF S Belongs to the UPF0342 family
KIKKMPBN_01508 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KIKKMPBN_01509 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KIKKMPBN_01512 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KIKKMPBN_01513 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
KIKKMPBN_01514 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KIKKMPBN_01515 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KIKKMPBN_01516 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KIKKMPBN_01517 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KIKKMPBN_01518 8.7e-41 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KIKKMPBN_01519 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
KIKKMPBN_01520 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
KIKKMPBN_01521 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KIKKMPBN_01522 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KIKKMPBN_01523 1.4e-41 ylxQ J ribosomal protein
KIKKMPBN_01524 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KIKKMPBN_01525 3.1e-212 nusA K Participates in both transcription termination and antitermination
KIKKMPBN_01526 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KIKKMPBN_01527 2.8e-219 brpA K Transcriptional
KIKKMPBN_01528 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
KIKKMPBN_01529 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KIKKMPBN_01530 1.9e-248 pbuO S permease
KIKKMPBN_01531 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KIKKMPBN_01532 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KIKKMPBN_01533 1.1e-181 manL 2.7.1.191 G pts system
KIKKMPBN_01534 2.3e-116 manM G pts system
KIKKMPBN_01535 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
KIKKMPBN_01536 4.2e-62 manO S protein conserved in bacteria
KIKKMPBN_01537 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KIKKMPBN_01538 7.8e-28 L transposase activity
KIKKMPBN_01539 5.7e-23 L Transposase
KIKKMPBN_01540 3.4e-50 L transposition
KIKKMPBN_01541 3e-27 L Integrase core domain protein
KIKKMPBN_01542 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
KIKKMPBN_01543 1.2e-34
KIKKMPBN_01545 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KIKKMPBN_01546 4.4e-166 dnaI L Primosomal protein DnaI
KIKKMPBN_01547 6.5e-218 dnaB L Replication initiation and membrane attachment
KIKKMPBN_01548 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KIKKMPBN_01549 2.8e-282 T PhoQ Sensor
KIKKMPBN_01550 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KIKKMPBN_01551 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
KIKKMPBN_01552 1.2e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KIKKMPBN_01553 2.7e-244 P COG0168 Trk-type K transport systems, membrane components
KIKKMPBN_01554 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
KIKKMPBN_01555 6.9e-11 ulaG S L-ascorbate 6-phosphate lactonase
KIKKMPBN_01556 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KIKKMPBN_01557 4.7e-146 cbiQ P cobalt transport
KIKKMPBN_01558 0.0 ykoD P abc transporter atp-binding protein
KIKKMPBN_01559 9.4e-95 S UPF0397 protein
KIKKMPBN_01560 9.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KIKKMPBN_01561 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KIKKMPBN_01562 8.8e-98 metI P ABC transporter (Permease
KIKKMPBN_01563 7.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KIKKMPBN_01564 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KIKKMPBN_01565 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KIKKMPBN_01566 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KIKKMPBN_01567 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
KIKKMPBN_01568 4e-153 ET amino acid transport
KIKKMPBN_01569 3.8e-205 EGP Transmembrane secretion effector
KIKKMPBN_01570 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
KIKKMPBN_01571 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KIKKMPBN_01572 5.3e-153 ET amino acid transport
KIKKMPBN_01573 1.6e-131 cbiO P ABC transporter
KIKKMPBN_01574 1.1e-136 P cobalt transport protein
KIKKMPBN_01575 4.3e-175 cbiM P PDGLE domain
KIKKMPBN_01576 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KIKKMPBN_01577 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KIKKMPBN_01578 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KIKKMPBN_01579 6.6e-78 ureE O enzyme active site formation
KIKKMPBN_01580 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KIKKMPBN_01581 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KIKKMPBN_01582 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KIKKMPBN_01583 6.8e-95 ureI S AmiS/UreI family transporter
KIKKMPBN_01584 9.2e-132 S Domain of unknown function (DUF4173)
KIKKMPBN_01585 6.7e-36 S Domain of unknown function (DUF4173)
KIKKMPBN_01586 3.7e-51 yhaI L Membrane
KIKKMPBN_01587 2.4e-170 L Integrase
KIKKMPBN_01588 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIKKMPBN_01589 1.8e-27 comA V protein secretion by the type I secretion system
KIKKMPBN_01590 1.1e-34 V protein secretion by the type I secretion system
KIKKMPBN_01591 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIKKMPBN_01592 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIKKMPBN_01593 1.2e-32 V protein secretion by the type I secretion system
KIKKMPBN_01594 5.6e-161 K sequence-specific DNA binding
KIKKMPBN_01595 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KIKKMPBN_01596 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KIKKMPBN_01597 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KIKKMPBN_01598 1.5e-247 trkA P Potassium transporter peripheral membrane component
KIKKMPBN_01599 1.2e-258 trkH P Cation transport protein
KIKKMPBN_01600 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KIKKMPBN_01601 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KIKKMPBN_01602 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KIKKMPBN_01603 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KIKKMPBN_01604 3.7e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KIKKMPBN_01605 2.1e-85 ykuL S CBS domain
KIKKMPBN_01606 3.5e-99 XK27_09740 S Phosphoesterase
KIKKMPBN_01607 6e-185 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KIKKMPBN_01608 4.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KIKKMPBN_01609 7.6e-36 yneF S UPF0154 protein
KIKKMPBN_01610 1.4e-90 K transcriptional regulator
KIKKMPBN_01611 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KIKKMPBN_01614 8.8e-98 ybhL S Belongs to the BI1 family
KIKKMPBN_01615 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KIKKMPBN_01616 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIKKMPBN_01617 8.4e-19 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KIKKMPBN_01618 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KIKKMPBN_01619 5.2e-59 L Integrase core domain protein
KIKKMPBN_01620 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KIKKMPBN_01621 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KIKKMPBN_01622 9.3e-46 XK27_09675 K -acetyltransferase
KIKKMPBN_01623 4e-20 XK27_09675 K -acetyltransferase
KIKKMPBN_01624 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KIKKMPBN_01625 2.5e-23
KIKKMPBN_01626 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KIKKMPBN_01627 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KIKKMPBN_01628 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KIKKMPBN_01629 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KIKKMPBN_01630 3.1e-95 ypsA S Belongs to the UPF0398 family
KIKKMPBN_01631 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KIKKMPBN_01632 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KIKKMPBN_01633 1.5e-258 pepC 3.4.22.40 E aminopeptidase
KIKKMPBN_01634 1.9e-77 yhaI L Membrane
KIKKMPBN_01635 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KIKKMPBN_01636 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KIKKMPBN_01637 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
KIKKMPBN_01638 2.6e-76 S thiolester hydrolase activity
KIKKMPBN_01640 3.8e-40 K transcriptional
KIKKMPBN_01642 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KIKKMPBN_01643 3.9e-21 glcR K transcriptional regulator (DeoR family)
KIKKMPBN_01644 4.7e-79 glcR K transcriptional regulator (DeoR family)
KIKKMPBN_01645 1.1e-34 cof Q phosphatase activity
KIKKMPBN_01646 6e-55 cof Q phosphatase activity
KIKKMPBN_01647 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KIKKMPBN_01648 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KIKKMPBN_01649 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
KIKKMPBN_01650 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KIKKMPBN_01651 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KIKKMPBN_01652 6.8e-56 S TM2 domain
KIKKMPBN_01653 4.7e-43
KIKKMPBN_01656 8.7e-31 L transposition
KIKKMPBN_01657 6.4e-18 L transposase activity
KIKKMPBN_01658 4.4e-37 L Transposase
KIKKMPBN_01659 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KIKKMPBN_01660 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KIKKMPBN_01661 5.2e-142 cmpC S abc transporter atp-binding protein
KIKKMPBN_01662 0.0 WQ51_06230 S ABC transporter substrate binding protein
KIKKMPBN_01663 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KIKKMPBN_01664 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KIKKMPBN_01665 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KIKKMPBN_01666 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KIKKMPBN_01667 9.8e-50 yajC U protein transport
KIKKMPBN_01668 1.9e-127 yeeN K transcriptional regulatory protein
KIKKMPBN_01669 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
KIKKMPBN_01670 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
KIKKMPBN_01671 1.5e-104 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KIKKMPBN_01672 5.1e-149 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
KIKKMPBN_01673 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
KIKKMPBN_01674 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KIKKMPBN_01675 2.5e-128 adcB P ABC transporter (Permease
KIKKMPBN_01676 6.4e-136 adcC P ABC transporter, ATP-binding protein
KIKKMPBN_01677 3.1e-72 adcR K transcriptional
KIKKMPBN_01678 1.9e-223 EGP Major facilitator Superfamily
KIKKMPBN_01679 0.0 KLT serine threonine protein kinase
KIKKMPBN_01680 6e-128 K sequence-specific DNA binding
KIKKMPBN_01681 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KIKKMPBN_01682 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KIKKMPBN_01683 2.7e-21
KIKKMPBN_01684 3.4e-62 oppF P Belongs to the ABC transporter superfamily
KIKKMPBN_01685 7.5e-62 oppF P Belongs to the ABC transporter superfamily
KIKKMPBN_01686 3.1e-43 oppD P Belongs to the ABC transporter superfamily
KIKKMPBN_01687 1.2e-62 oppD P Belongs to the ABC transporter superfamily
KIKKMPBN_01688 2.5e-32 oppD P Belongs to the ABC transporter superfamily
KIKKMPBN_01689 3e-27 oppD P Belongs to the ABC transporter superfamily
KIKKMPBN_01690 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIKKMPBN_01691 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIKKMPBN_01692 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIKKMPBN_01693 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KIKKMPBN_01694 2.3e-139 oppA E ABC transporter substrate-binding protein
KIKKMPBN_01695 7e-10 oppA E ABC transporter substrate-binding protein
KIKKMPBN_01696 2.2e-273 sufB O assembly protein SufB
KIKKMPBN_01697 1.2e-73 nifU C SUF system FeS assembly protein, NifU family
KIKKMPBN_01698 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KIKKMPBN_01699 6.3e-235 sufD O assembly protein SufD
KIKKMPBN_01700 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KIKKMPBN_01701 7.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
KIKKMPBN_01702 1.4e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KIKKMPBN_01703 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KIKKMPBN_01704 5.8e-275 glnP P ABC transporter
KIKKMPBN_01705 1e-123 glnQ E abc transporter atp-binding protein
KIKKMPBN_01707 5e-94 V VanZ like family
KIKKMPBN_01708 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KIKKMPBN_01709 9.3e-201 yhjX P Major Facilitator
KIKKMPBN_01710 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KIKKMPBN_01711 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KIKKMPBN_01712 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KIKKMPBN_01713 2.5e-45 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KIKKMPBN_01714 5.6e-59 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KIKKMPBN_01715 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KIKKMPBN_01716 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KIKKMPBN_01717 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KIKKMPBN_01718 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KIKKMPBN_01719 1.8e-83 nrdI F Belongs to the NrdI family
KIKKMPBN_01720 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KIKKMPBN_01721 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KIKKMPBN_01722 9.2e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KIKKMPBN_01723 1.4e-42 F nucleotide catabolic process
KIKKMPBN_01724 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KIKKMPBN_01725 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
KIKKMPBN_01726 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KIKKMPBN_01727 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
KIKKMPBN_01728 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KIKKMPBN_01729 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KIKKMPBN_01730 3.2e-218 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KIKKMPBN_01731 9.3e-150 ykuT M mechanosensitive ion channel
KIKKMPBN_01732 1.6e-77 sigH K DNA-templated transcription, initiation
KIKKMPBN_01733 1e-84
KIKKMPBN_01734 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KIKKMPBN_01735 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KIKKMPBN_01737 4.2e-35 amiA E ABC transporter, substrate-binding protein, family 5
KIKKMPBN_01738 1.7e-60 hmpT S membrane
KIKKMPBN_01739 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KIKKMPBN_01740 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KIKKMPBN_01741 9.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KIKKMPBN_01742 7.5e-298 dnaK O Heat shock 70 kDa protein
KIKKMPBN_01743 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KIKKMPBN_01744 5.8e-197 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KIKKMPBN_01745 1.3e-102 acmA 3.2.1.17 NU amidase activity
KIKKMPBN_01746 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KIKKMPBN_01747 2.2e-38 ais G alpha-ribazole phosphatase activity
KIKKMPBN_01748 1.9e-242 XK27_08635 S UPF0210 protein
KIKKMPBN_01749 3.6e-39 gcvR T UPF0237 protein
KIKKMPBN_01750 3.3e-225 capA M Bacterial capsule synthesis protein
KIKKMPBN_01751 5.7e-91 tnp L Transposase
KIKKMPBN_01752 3.4e-75 isp2 S pathogenesis
KIKKMPBN_01754 4.9e-173
KIKKMPBN_01755 2.8e-39 S Helix-turn-helix domain
KIKKMPBN_01756 5.9e-222 int L Belongs to the 'phage' integrase family
KIKKMPBN_01757 5.9e-91 3.6.4.12 K Divergent AAA domain protein
KIKKMPBN_01758 5.9e-24 3.6.4.12
KIKKMPBN_01759 2.5e-183 EGP Major facilitator Superfamily
KIKKMPBN_01760 2.4e-231 spaC2 V Lanthionine synthetase C family protein
KIKKMPBN_01761 0.0 S Lantibiotic dehydratase, C terminus
KIKKMPBN_01763 1.5e-35 K sequence-specific DNA binding
KIKKMPBN_01764 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KIKKMPBN_01765 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KIKKMPBN_01766 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KIKKMPBN_01767 1.8e-31 K helix-turn-helix
KIKKMPBN_01768 3.4e-155 degV S DegV family
KIKKMPBN_01769 3.5e-91 yacP S RNA-binding protein containing a PIN domain
KIKKMPBN_01770 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KIKKMPBN_01773 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KIKKMPBN_01774 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KIKKMPBN_01775 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
KIKKMPBN_01776 7.9e-106 S SseB protein N-terminal domain
KIKKMPBN_01777 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KIKKMPBN_01778 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KIKKMPBN_01779 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KIKKMPBN_01780 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KIKKMPBN_01781 0.0 clpC O Belongs to the ClpA ClpB family
KIKKMPBN_01782 6.2e-76 ctsR K Belongs to the CtsR family
KIKKMPBN_01783 1.1e-83 S Putative small multi-drug export protein
KIKKMPBN_01784 3e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KIKKMPBN_01785 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KIKKMPBN_01788 3.2e-68 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KIKKMPBN_01789 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
KIKKMPBN_01791 6.4e-41 L transposition
KIKKMPBN_01792 6.9e-89 L Integrase core domain protein
KIKKMPBN_01793 3.5e-97 S reductase
KIKKMPBN_01794 2.6e-55 badR K DNA-binding transcription factor activity
KIKKMPBN_01795 5.5e-36 XK27_02060 S Transglycosylase associated protein
KIKKMPBN_01796 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KIKKMPBN_01797 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KIKKMPBN_01802 1.9e-07
KIKKMPBN_01805 2.6e-10
KIKKMPBN_01811 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
KIKKMPBN_01812 2e-09 L thioesterase
KIKKMPBN_01813 6.6e-142 S Macro domain protein
KIKKMPBN_01814 4.8e-51 trxA O Belongs to the thioredoxin family
KIKKMPBN_01815 2.5e-74 yccU S CoA-binding protein
KIKKMPBN_01816 4.1e-144 tatD L Hydrolase, tatd
KIKKMPBN_01817 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KIKKMPBN_01818 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KIKKMPBN_01820 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KIKKMPBN_01821 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KIKKMPBN_01822 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
KIKKMPBN_01823 6.9e-173 rmuC S RmuC domain protein
KIKKMPBN_01824 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
KIKKMPBN_01825 1.1e-142 purR 2.4.2.7 F operon repressor
KIKKMPBN_01826 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KIKKMPBN_01827 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KIKKMPBN_01828 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KIKKMPBN_01829 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KIKKMPBN_01830 6.1e-114 L Transposase
KIKKMPBN_01831 1e-102 L Transposase
KIKKMPBN_01832 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KIKKMPBN_01833 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KIKKMPBN_01834 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
KIKKMPBN_01835 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KIKKMPBN_01836 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KIKKMPBN_01838 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KIKKMPBN_01840 6.5e-63 KT phosphorelay signal transduction system
KIKKMPBN_01841 1.9e-80 S Protein of unknown function (DUF3021)
KIKKMPBN_01842 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KIKKMPBN_01843 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KIKKMPBN_01844 8.2e-70 argR K Regulates arginine biosynthesis genes
KIKKMPBN_01846 1.3e-57 T Toxic component of a toxin-antitoxin (TA) module
KIKKMPBN_01849 1.7e-27 amiA E ABC transporter, substrate-binding protein, family 5
KIKKMPBN_01850 4e-10 L Transposase
KIKKMPBN_01851 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KIKKMPBN_01852 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KIKKMPBN_01853 2e-140 1.1.1.169 H Ketopantoate reductase
KIKKMPBN_01854 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KIKKMPBN_01855 3.8e-70 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KIKKMPBN_01856 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
KIKKMPBN_01857 2.3e-161 S CHAP domain
KIKKMPBN_01858 2e-32 L Integrase core domain protein
KIKKMPBN_01859 3.5e-50 L transposition
KIKKMPBN_01860 1e-90 L transposase activity
KIKKMPBN_01861 1.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KIKKMPBN_01862 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KIKKMPBN_01863 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KIKKMPBN_01864 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KIKKMPBN_01865 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KIKKMPBN_01866 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KIKKMPBN_01867 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KIKKMPBN_01868 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KIKKMPBN_01869 7e-144 recO L Involved in DNA repair and RecF pathway recombination
KIKKMPBN_01870 2.9e-218 araT 2.6.1.1 E Aminotransferase
KIKKMPBN_01871 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KIKKMPBN_01872 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
KIKKMPBN_01873 9.1e-87 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KIKKMPBN_01874 5.5e-139 mreC M Involved in formation and maintenance of cell shape
KIKKMPBN_01879 5.3e-11
KIKKMPBN_01888 1.8e-56 L transposition
KIKKMPBN_01889 7.4e-23 L Transposase
KIKKMPBN_01890 1.9e-46 L transposase activity
KIKKMPBN_01891 3.2e-42 L Transposase
KIKKMPBN_01892 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KIKKMPBN_01893 8.9e-30
KIKKMPBN_01894 1.1e-12
KIKKMPBN_01895 1.3e-87 S Fusaric acid resistance protein-like
KIKKMPBN_01896 8.5e-63 glnR K Transcriptional regulator
KIKKMPBN_01897 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
KIKKMPBN_01898 2.7e-40 pscB M CHAP domain protein
KIKKMPBN_01899 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KIKKMPBN_01900 2.5e-33 ykzG S Belongs to the UPF0356 family
KIKKMPBN_01901 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KIKKMPBN_01902 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KIKKMPBN_01903 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KIKKMPBN_01904 1.8e-114 azlC E AzlC protein
KIKKMPBN_01905 2e-47 azlD E branched-chain amino acid
KIKKMPBN_01906 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KIKKMPBN_01907 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KIKKMPBN_01908 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KIKKMPBN_01909 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KIKKMPBN_01910 1e-93 cvpA S toxin biosynthetic process
KIKKMPBN_01911 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KIKKMPBN_01912 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KIKKMPBN_01917 4.2e-230 mutY L A G-specific adenine glycosylase
KIKKMPBN_01918 9.5e-42 XK27_05745
KIKKMPBN_01919 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KIKKMPBN_01920 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KIKKMPBN_01921 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KIKKMPBN_01923 3.1e-124 XK27_01040 S Pfam PF06570
KIKKMPBN_01924 2e-169 corA P COG0598 Mg2 and Co2 transporters
KIKKMPBN_01925 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KIKKMPBN_01928 1e-58 V 'abc transporter, ATP-binding protein
KIKKMPBN_01929 8e-44 V 'abc transporter, ATP-binding protein
KIKKMPBN_01931 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KIKKMPBN_01932 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
KIKKMPBN_01933 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KIKKMPBN_01934 3.4e-62 yqhY S protein conserved in bacteria
KIKKMPBN_01935 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KIKKMPBN_01936 7.5e-180 scrR K Transcriptional
KIKKMPBN_01937 5.4e-291 scrB 3.2.1.26 GH32 G invertase
KIKKMPBN_01938 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
KIKKMPBN_01939 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KIKKMPBN_01940 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KIKKMPBN_01942 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KIKKMPBN_01943 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KIKKMPBN_01944 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KIKKMPBN_01945 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KIKKMPBN_01946 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KIKKMPBN_01947 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KIKKMPBN_01948 1.8e-181 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KIKKMPBN_01949 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
KIKKMPBN_01950 2.9e-18 yebC M Membrane
KIKKMPBN_01951 6.8e-81 yebC M Membrane
KIKKMPBN_01952 1.8e-65 KT response to antibiotic
KIKKMPBN_01953 5.2e-75 XK27_02470 K LytTr DNA-binding domain
KIKKMPBN_01954 2.6e-121 liaI S membrane
KIKKMPBN_01955 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KIKKMPBN_01956 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KIKKMPBN_01957 5.2e-125 S Protein of unknown function (DUF554)
KIKKMPBN_01958 8.1e-134 ecsA_2 V abc transporter atp-binding protein
KIKKMPBN_01959 2.2e-285 XK27_00765
KIKKMPBN_01960 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KIKKMPBN_01961 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KIKKMPBN_01962 1.3e-08 D nuclear chromosome segregation
KIKKMPBN_01963 9.7e-32 yhaI J Protein of unknown function (DUF805)
KIKKMPBN_01965 3e-128
KIKKMPBN_01966 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KIKKMPBN_01967 8.1e-46 ftsL D cell division protein FtsL
KIKKMPBN_01968 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KIKKMPBN_01969 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KIKKMPBN_01970 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KIKKMPBN_01972 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KIKKMPBN_01973 2.3e-72 yutD J protein conserved in bacteria
KIKKMPBN_01974 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KIKKMPBN_01975 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
KIKKMPBN_01977 0.0 mdlA V abc transporter atp-binding protein
KIKKMPBN_01978 0.0 mdlB V abc transporter atp-binding protein
KIKKMPBN_01979 2.8e-108 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIKKMPBN_01980 9.3e-281 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KIKKMPBN_01981 1.6e-236 mesE M Transport protein ComB
KIKKMPBN_01983 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
KIKKMPBN_01984 7.4e-135 agrA KT phosphorelay signal transduction system
KIKKMPBN_01987 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
KIKKMPBN_01992 2.2e-177 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KIKKMPBN_01993 8.4e-205 nodC 2.4.1.212 GT2 M Chitin synthase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)