ORF_ID e_value Gene_name EC_number CAZy COGs Description
HEBFJANG_00001 1.3e-137 L Transposase
HEBFJANG_00002 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEBFJANG_00003 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HEBFJANG_00004 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEBFJANG_00005 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HEBFJANG_00007 2.7e-61 divIC D Septum formation initiator
HEBFJANG_00008 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HEBFJANG_00009 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEBFJANG_00010 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEBFJANG_00011 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEBFJANG_00012 1.1e-29 yyzM S Protein conserved in bacteria
HEBFJANG_00013 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEBFJANG_00014 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEBFJANG_00015 8.5e-134 parB K Belongs to the ParB family
HEBFJANG_00016 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HEBFJANG_00017 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEBFJANG_00018 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
HEBFJANG_00022 0.0 XK27_10405 S Bacterial membrane protein YfhO
HEBFJANG_00023 6.7e-306 ybiT S abc transporter atp-binding protein
HEBFJANG_00024 4.2e-153 yvjA S membrane
HEBFJANG_00025 3.1e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HEBFJANG_00026 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEBFJANG_00027 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEBFJANG_00028 1.6e-45 yaaA S S4 domain protein YaaA
HEBFJANG_00029 1.7e-66 ymfF S Peptidase M16
HEBFJANG_00030 1.3e-156 ymfF S Peptidase M16
HEBFJANG_00031 1.2e-241 ymfH S Peptidase M16
HEBFJANG_00032 6.3e-138 ymfM S sequence-specific DNA binding
HEBFJANG_00033 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEBFJANG_00034 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEBFJANG_00035 2e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEBFJANG_00036 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEBFJANG_00037 5.3e-85 lytE M LysM domain protein
HEBFJANG_00038 1.7e-63 isaA GH23 M Immunodominant staphylococcal antigen A
HEBFJANG_00039 0.0 S Bacterial membrane protein, YfhO
HEBFJANG_00040 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEBFJANG_00041 1.5e-77 F NUDIX domain
HEBFJANG_00042 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEBFJANG_00043 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HEBFJANG_00044 3.9e-70 rplI J binds to the 23S rRNA
HEBFJANG_00045 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HEBFJANG_00046 8.2e-48 veg S Biofilm formation stimulator VEG
HEBFJANG_00047 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEBFJANG_00048 2.7e-08
HEBFJANG_00049 4.8e-55 ypaA M Membrane
HEBFJANG_00050 6.4e-96 XK27_06935 K transcriptional regulator
HEBFJANG_00051 3.9e-161 XK27_06930 V domain protein
HEBFJANG_00052 1.2e-87 S Putative adhesin
HEBFJANG_00053 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
HEBFJANG_00055 1.7e-23 K negative regulation of transcription, DNA-templated
HEBFJANG_00056 4e-19 K negative regulation of transcription, DNA-templated
HEBFJANG_00057 3.4e-13 nudL L hydrolase
HEBFJANG_00058 1.1e-11 K CsbD-like
HEBFJANG_00059 3.1e-85 M Protein conserved in bacteria
HEBFJANG_00060 1.8e-23 S Small integral membrane protein
HEBFJANG_00061 9.1e-101
HEBFJANG_00062 3.7e-27 S Membrane
HEBFJANG_00064 2.7e-95 S Hydrophobic domain protein
HEBFJANG_00065 1.5e-49 yegS 2.7.1.107 I lipid kinase activity
HEBFJANG_00068 5.1e-184 sip L Belongs to the 'phage' integrase family
HEBFJANG_00069 5.9e-20 S MerR HTH family regulatory protein
HEBFJANG_00070 2.1e-82 S Plasmid replication protein
HEBFJANG_00071 2e-20
HEBFJANG_00072 1.5e-160 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HEBFJANG_00073 1.7e-35
HEBFJANG_00074 3.2e-10 S Sigma-70, region 4
HEBFJANG_00075 0.0 V Type II restriction enzyme, methylase subunits
HEBFJANG_00076 2.4e-28
HEBFJANG_00077 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEBFJANG_00078 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HEBFJANG_00079 1.4e-36 metE 2.1.1.14 E Methionine synthase
HEBFJANG_00080 5.2e-55 metE 2.1.1.14 E Methionine synthase
HEBFJANG_00081 1.4e-53 metE 2.1.1.14 E Methionine synthase
HEBFJANG_00082 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
HEBFJANG_00084 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HEBFJANG_00085 9.3e-167 XK27_01785 S cog cog1284
HEBFJANG_00086 1.8e-147 yaaA S Belongs to the UPF0246 family
HEBFJANG_00087 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEBFJANG_00088 2.6e-91 XK27_10930 K acetyltransferase
HEBFJANG_00089 7.5e-14
HEBFJANG_00090 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HEBFJANG_00091 2.8e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
HEBFJANG_00092 4.2e-44 yrzB S Belongs to the UPF0473 family
HEBFJANG_00093 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEBFJANG_00094 2.8e-44 yrzL S Belongs to the UPF0297 family
HEBFJANG_00095 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HEBFJANG_00096 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HEBFJANG_00098 1.7e-215 int L Belongs to the 'phage' integrase family
HEBFJANG_00099 1.9e-18 S Domain of unknown function (DUF3173)
HEBFJANG_00100 5.9e-156 L Replication initiation factor
HEBFJANG_00101 3.9e-287 V ABC transporter transmembrane region
HEBFJANG_00102 3e-104 C Radical SAM
HEBFJANG_00103 7.5e-109 C Radical SAM
HEBFJANG_00105 1.4e-59 Z012_04635 K sequence-specific DNA binding
HEBFJANG_00106 3.2e-56 Z012_04635 K sequence-specific DNA binding
HEBFJANG_00107 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HEBFJANG_00108 9.7e-30 S Domain of unknown function (DUF4649)
HEBFJANG_00109 7.6e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEBFJANG_00110 1.8e-50 adk 2.7.4.3 F topology modulation protein
HEBFJANG_00111 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEBFJANG_00112 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEBFJANG_00113 1.7e-35 XK27_09805 S MORN repeat protein
HEBFJANG_00114 0.0 XK27_09800 I Acyltransferase
HEBFJANG_00115 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEBFJANG_00116 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HEBFJANG_00117 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEBFJANG_00118 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
HEBFJANG_00119 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEBFJANG_00120 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEBFJANG_00121 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEBFJANG_00122 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEBFJANG_00123 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEBFJANG_00124 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEBFJANG_00125 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HEBFJANG_00126 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEBFJANG_00127 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEBFJANG_00128 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEBFJANG_00129 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEBFJANG_00130 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEBFJANG_00131 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEBFJANG_00132 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEBFJANG_00133 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEBFJANG_00134 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEBFJANG_00135 2.5e-23 rpmD J ribosomal protein l30
HEBFJANG_00136 4.4e-58 rplO J binds to the 23S rRNA
HEBFJANG_00137 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEBFJANG_00138 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEBFJANG_00139 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEBFJANG_00140 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HEBFJANG_00141 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEBFJANG_00142 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEBFJANG_00143 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEBFJANG_00144 3.3e-62 rplQ J ribosomal protein l17
HEBFJANG_00145 9.8e-94 L PFAM Integrase, catalytic core
HEBFJANG_00146 2e-35 L PFAM Integrase, catalytic core
HEBFJANG_00149 3.3e-95 ywlG S Belongs to the UPF0340 family
HEBFJANG_00150 1.2e-85 treR K trehalose operon
HEBFJANG_00151 5.8e-21 treR K DNA-binding transcription factor activity
HEBFJANG_00152 1.4e-54 treB 2.7.1.201 G PTS System
HEBFJANG_00153 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HEBFJANG_00154 1.5e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HEBFJANG_00155 0.0 pepO 3.4.24.71 O Peptidase family M13
HEBFJANG_00156 2.1e-52 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
HEBFJANG_00157 1.2e-133 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HEBFJANG_00158 7.3e-74 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HEBFJANG_00159 4.1e-22 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HEBFJANG_00160 6.1e-64 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HEBFJANG_00161 1.2e-277 thrC 4.2.3.1 E Threonine synthase
HEBFJANG_00162 3.2e-226 norN V Mate efflux family protein
HEBFJANG_00163 1.8e-57 asp S cog cog1302
HEBFJANG_00164 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
HEBFJANG_00165 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HEBFJANG_00166 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HEBFJANG_00167 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
HEBFJANG_00168 1.5e-194 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEBFJANG_00169 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEBFJANG_00170 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEBFJANG_00171 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEBFJANG_00172 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEBFJANG_00173 2.9e-68 S cog cog4699
HEBFJANG_00174 6e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEBFJANG_00175 9.1e-156 cglB U protein transport across the cell outer membrane
HEBFJANG_00176 8.5e-43 comGC U Required for transformation and DNA binding
HEBFJANG_00177 1.8e-57 cglD NU Competence protein
HEBFJANG_00178 1.4e-15 NU Type II secretory pathway pseudopilin
HEBFJANG_00179 1.5e-71 comGF U Competence protein ComGF
HEBFJANG_00180 2e-12 comGF U Putative Competence protein ComGF
HEBFJANG_00181 1.1e-175 ytxK 2.1.1.72 L DNA methylase
HEBFJANG_00182 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEBFJANG_00183 2.6e-26 lanR K sequence-specific DNA binding
HEBFJANG_00184 1.1e-66 V CAAX protease self-immunity
HEBFJANG_00186 8.7e-111 S CAAX amino terminal protease family protein
HEBFJANG_00187 4.6e-42 3.6.1.55 F NUDIX domain
HEBFJANG_00188 4.6e-152 mutR K Transcriptional activator, Rgg GadR MutR family
HEBFJANG_00189 1.6e-140 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
HEBFJANG_00190 7.2e-286 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
HEBFJANG_00191 6.6e-213 EGP Major facilitator Superfamily
HEBFJANG_00195 8.7e-159 XK27_09825 V abc transporter atp-binding protein
HEBFJANG_00196 1.4e-133 yvfS V ABC-2 type transporter
HEBFJANG_00197 1.5e-192 desK 2.7.13.3 T Histidine kinase
HEBFJANG_00198 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBFJANG_00199 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
HEBFJANG_00200 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HEBFJANG_00201 1.2e-48 S Protein of unknown function (DUF917)
HEBFJANG_00202 1.4e-133 S Protein of unknown function (DUF917)
HEBFJANG_00203 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
HEBFJANG_00204 3e-111 proWZ P ABC transporter (Permease
HEBFJANG_00205 7.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
HEBFJANG_00206 1.5e-138 proV E abc transporter atp-binding protein
HEBFJANG_00207 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
HEBFJANG_00208 1.2e-62 bioY S biotin transmembrane transporter activity
HEBFJANG_00209 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HEBFJANG_00210 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEBFJANG_00211 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEBFJANG_00212 6.3e-23
HEBFJANG_00213 3e-13
HEBFJANG_00214 2.4e-92 pat 2.3.1.183 M acetyltransferase
HEBFJANG_00215 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEBFJANG_00216 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEBFJANG_00217 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEBFJANG_00218 0.0 smc D Required for chromosome condensation and partitioning
HEBFJANG_00219 1.2e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEBFJANG_00220 4.6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBFJANG_00221 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEBFJANG_00224 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HEBFJANG_00225 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEBFJANG_00227 2e-86 S ECF-type riboflavin transporter, S component
HEBFJANG_00228 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HEBFJANG_00229 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HEBFJANG_00230 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
HEBFJANG_00231 1.9e-294 yfmM S abc transporter atp-binding protein
HEBFJANG_00232 3.4e-258 noxE P NADH oxidase
HEBFJANG_00233 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HEBFJANG_00234 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEBFJANG_00235 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HEBFJANG_00236 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
HEBFJANG_00237 5.3e-165 ypuA S secreted protein
HEBFJANG_00238 8.8e-60 L Transposase (IS116 IS110 IS902 family)
HEBFJANG_00239 4.2e-71 L Transposase (IS116 IS110 IS902 family)
HEBFJANG_00241 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBFJANG_00242 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEBFJANG_00243 2.2e-34 nrdH O Glutaredoxin
HEBFJANG_00244 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEBFJANG_00245 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
HEBFJANG_00246 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
HEBFJANG_00247 7.9e-39 ptsH G phosphocarrier protein Hpr
HEBFJANG_00248 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEBFJANG_00249 4.1e-181 L Transposase
HEBFJANG_00250 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HEBFJANG_00251 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HEBFJANG_00252 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
HEBFJANG_00253 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HEBFJANG_00254 0.0 uup S abc transporter atp-binding protein
HEBFJANG_00256 6.3e-13 MA20_06245 S yiaA/B two helix domain
HEBFJANG_00257 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
HEBFJANG_00258 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEBFJANG_00259 8.7e-150 cobQ S glutamine amidotransferase
HEBFJANG_00260 1.1e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HEBFJANG_00261 1.2e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEBFJANG_00262 2.3e-168 ybbR S Protein conserved in bacteria
HEBFJANG_00263 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEBFJANG_00264 1.3e-70 gtrA S GtrA-like protein
HEBFJANG_00265 7.9e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HEBFJANG_00266 8.1e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEBFJANG_00267 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
HEBFJANG_00268 2.1e-207 yurR 1.4.5.1 E oxidoreductase
HEBFJANG_00269 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEBFJANG_00270 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HEBFJANG_00271 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEBFJANG_00274 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HEBFJANG_00275 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
HEBFJANG_00276 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEBFJANG_00277 1.1e-121 ylfI S tigr01906
HEBFJANG_00278 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HEBFJANG_00279 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HEBFJANG_00280 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HEBFJANG_00281 1.3e-22 XK27_08085
HEBFJANG_00282 5.2e-36 L transposase activity
HEBFJANG_00283 8.2e-22 L Transposase
HEBFJANG_00284 1.6e-55 L transposition
HEBFJANG_00285 8.2e-26 L Integrase core domain protein
HEBFJANG_00287 1.5e-29 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEBFJANG_00288 1.6e-154 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEBFJANG_00289 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEBFJANG_00290 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEBFJANG_00291 2.6e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEBFJANG_00292 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HEBFJANG_00293 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEBFJANG_00294 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEBFJANG_00295 8.3e-21 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEBFJANG_00296 1e-108 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEBFJANG_00297 1.2e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HEBFJANG_00298 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
HEBFJANG_00299 5.6e-240 rodA D Belongs to the SEDS family
HEBFJANG_00300 7.8e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEBFJANG_00301 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HEBFJANG_00302 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEBFJANG_00303 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFJANG_00304 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HEBFJANG_00305 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEBFJANG_00306 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEBFJANG_00307 2.9e-125 dnaD
HEBFJANG_00308 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEBFJANG_00311 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEBFJANG_00312 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
HEBFJANG_00313 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HEBFJANG_00314 4.7e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HEBFJANG_00315 3.7e-73 argR K Regulates arginine biosynthesis genes
HEBFJANG_00316 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
HEBFJANG_00317 1e-148 DegV S DegV family
HEBFJANG_00318 3.9e-143 ypmR E lipolytic protein G-D-S-L family
HEBFJANG_00319 1.7e-83 ypmS S Protein conserved in bacteria
HEBFJANG_00320 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEBFJANG_00322 1.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HEBFJANG_00323 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEBFJANG_00324 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEBFJANG_00325 7.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEBFJANG_00326 2.5e-43 ysdA L Membrane
HEBFJANG_00327 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEBFJANG_00328 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEBFJANG_00329 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
HEBFJANG_00330 0.0 dnaE 2.7.7.7 L DNA polymerase
HEBFJANG_00331 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEBFJANG_00332 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HEBFJANG_00335 6.1e-28 Q the current gene model (or a revised gene model) may contain a frame shift
HEBFJANG_00336 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
HEBFJANG_00337 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
HEBFJANG_00338 2.2e-146 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HEBFJANG_00339 4.4e-135 XK27_08845 S abc transporter atp-binding protein
HEBFJANG_00340 3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEBFJANG_00341 1.6e-151 estA CE1 S Putative esterase
HEBFJANG_00342 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
HEBFJANG_00343 3.3e-14 XK27_08880
HEBFJANG_00344 2.3e-75 fld C Flavodoxin
HEBFJANG_00345 1.3e-282 clcA P Chloride transporter, ClC family
HEBFJANG_00346 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HEBFJANG_00347 3.5e-206 XK27_05110 P Chloride transporter ClC family
HEBFJANG_00348 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEBFJANG_00350 5.8e-80
HEBFJANG_00351 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
HEBFJANG_00352 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEBFJANG_00353 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HEBFJANG_00354 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEBFJANG_00355 1.6e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEBFJANG_00356 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEBFJANG_00357 5.9e-26 G Domain of unknown function (DUF4832)
HEBFJANG_00358 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEBFJANG_00360 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEBFJANG_00361 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
HEBFJANG_00362 2.4e-124 endA F DNA RNA non-specific endonuclease
HEBFJANG_00363 4.2e-110 tcyB_2 P ABC transporter (permease)
HEBFJANG_00364 8e-115 gltJ P ABC transporter (Permease
HEBFJANG_00365 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HEBFJANG_00366 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
HEBFJANG_00367 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFJANG_00368 1.5e-247 vicK 2.7.13.3 T Histidine kinase
HEBFJANG_00369 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HEBFJANG_00370 5.3e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HEBFJANG_00371 4.6e-146 yidA S hydrolases of the HAD superfamily
HEBFJANG_00372 8.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
HEBFJANG_00373 2.6e-67 ywiB S Domain of unknown function (DUF1934)
HEBFJANG_00374 0.0 pacL 3.6.3.8 P cation transport ATPase
HEBFJANG_00375 1.7e-134 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HEBFJANG_00376 9.2e-183 yjjH S Calcineurin-like phosphoesterase
HEBFJANG_00377 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEBFJANG_00378 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEBFJANG_00379 2.5e-124 ftsE D cell division ATP-binding protein FtsE
HEBFJANG_00380 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEBFJANG_00381 1.7e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEBFJANG_00382 1.3e-178 yubA S permease
HEBFJANG_00383 4.9e-224 G COG0457 FOG TPR repeat
HEBFJANG_00384 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HEBFJANG_00385 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HEBFJANG_00386 2.9e-90 ebsA S Family of unknown function (DUF5322)
HEBFJANG_00387 3.9e-15 M LysM domain
HEBFJANG_00388 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HEBFJANG_00389 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEBFJANG_00390 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HEBFJANG_00391 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEBFJANG_00392 1.6e-24 L Transposase
HEBFJANG_00393 1.7e-47 XK27_03610 K Gnat family
HEBFJANG_00394 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HEBFJANG_00395 2.4e-275 pepV 3.5.1.18 E Dipeptidase
HEBFJANG_00396 1.5e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
HEBFJANG_00398 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HEBFJANG_00399 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEBFJANG_00400 9.6e-47 S Protein of unknown function (DUF1697)
HEBFJANG_00401 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEBFJANG_00402 6.1e-36 clcA_2 P chloride channel
HEBFJANG_00403 2.2e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
HEBFJANG_00404 4.1e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
HEBFJANG_00405 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HEBFJANG_00406 4.2e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HEBFJANG_00407 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HEBFJANG_00408 1.1e-103 cps4C M biosynthesis protein
HEBFJANG_00409 1.4e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
HEBFJANG_00410 1.7e-249 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HEBFJANG_00411 9.7e-23 rgpAc GT4 M group 1 family protein
HEBFJANG_00412 2.2e-22 L Transposase
HEBFJANG_00413 8.8e-139 L Integrase core domain
HEBFJANG_00414 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
HEBFJANG_00415 2.7e-184 L Transposase
HEBFJANG_00416 1.3e-23 L Transposase
HEBFJANG_00417 1.1e-235 cps1C S Polysaccharide biosynthesis protein
HEBFJANG_00418 3.2e-71 L COG2801 Transposase and inactivated derivatives
HEBFJANG_00419 1.1e-60 L Integrase core domain
HEBFJANG_00420 3.3e-37 L transposase activity
HEBFJANG_00421 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
HEBFJANG_00422 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
HEBFJANG_00423 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
HEBFJANG_00424 6.5e-72 M Glycosyltransferase sugar-binding region containing DXD motif
HEBFJANG_00425 7.8e-16
HEBFJANG_00426 6.4e-33 cpsJ S Glycosyltransferase like family 2
HEBFJANG_00427 6.2e-112 L the current gene model (or a revised gene model) may contain a frame shift
HEBFJANG_00428 3.1e-37 L Transposase
HEBFJANG_00429 2.2e-94 V VanZ like family
HEBFJANG_00430 5.4e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HEBFJANG_00431 5.6e-65 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
HEBFJANG_00432 1.1e-95 pgm G Belongs to the phosphoglycerate mutase family
HEBFJANG_00433 7.2e-104 G Belongs to the phosphoglycerate mutase family
HEBFJANG_00434 2.5e-99 G Belongs to the phosphoglycerate mutase family
HEBFJANG_00435 1.1e-198 S hmm pf01594
HEBFJANG_00436 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEBFJANG_00437 2.6e-97 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEBFJANG_00438 3.2e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEBFJANG_00439 4.9e-39 S granule-associated protein
HEBFJANG_00440 8.5e-290 S unusual protein kinase
HEBFJANG_00441 5.5e-34 estA E Lysophospholipase L1 and related esterases
HEBFJANG_00442 1.9e-59 estA E GDSL-like protein
HEBFJANG_00443 1.1e-158 rssA S Phospholipase, patatin family
HEBFJANG_00444 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
HEBFJANG_00445 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
HEBFJANG_00446 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
HEBFJANG_00447 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HEBFJANG_00448 5.4e-19 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HEBFJANG_00449 4e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEBFJANG_00450 7.2e-126 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEBFJANG_00451 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEBFJANG_00452 5.7e-66 S the current gene model (or a revised gene model) may contain a frame shift
HEBFJANG_00453 5e-38 P membrane protein (DUF2207)
HEBFJANG_00454 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HEBFJANG_00455 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEBFJANG_00456 2.8e-196 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEBFJANG_00457 0.0 lpdA 1.8.1.4 C Dehydrogenase
HEBFJANG_00458 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HEBFJANG_00459 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HEBFJANG_00460 8.5e-266 3.5.1.28 NU amidase activity
HEBFJANG_00461 1.9e-37 3.5.1.28 NU amidase activity
HEBFJANG_00462 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HEBFJANG_00463 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HEBFJANG_00464 3.8e-54 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HEBFJANG_00465 2e-139 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HEBFJANG_00466 4e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFJANG_00467 1.9e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEBFJANG_00468 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
HEBFJANG_00469 6.5e-177 fatB P ABC-type enterochelin transport system, periplasmic component
HEBFJANG_00470 4.6e-152 ycdO P periplasmic lipoprotein involved in iron transport
HEBFJANG_00471 1.5e-233 ycdB P peroxidase
HEBFJANG_00472 3.9e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HEBFJANG_00473 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEBFJANG_00474 4.6e-25 tatA U protein secretion
HEBFJANG_00475 2.3e-23 L Transposase
HEBFJANG_00476 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
HEBFJANG_00477 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEBFJANG_00478 3.7e-09
HEBFJANG_00480 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
HEBFJANG_00481 1.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HEBFJANG_00482 0.0 pepN 3.4.11.2 E aminopeptidase
HEBFJANG_00483 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
HEBFJANG_00484 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEBFJANG_00485 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEBFJANG_00486 5.9e-155 pstA P phosphate transport system permease
HEBFJANG_00487 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HEBFJANG_00488 4.3e-158 pstS P phosphate
HEBFJANG_00489 1.5e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HEBFJANG_00490 1.1e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HEBFJANG_00491 1.9e-43 yktA S Belongs to the UPF0223 family
HEBFJANG_00492 4.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEBFJANG_00493 2.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HEBFJANG_00494 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEBFJANG_00495 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
HEBFJANG_00496 3.6e-136 XK27_04775 S hemerythrin HHE cation binding domain
HEBFJANG_00497 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HEBFJANG_00498 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEBFJANG_00499 9.3e-62 S haloacid dehalogenase-like hydrolase
HEBFJANG_00500 1.8e-59 Q phosphatase activity
HEBFJANG_00501 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
HEBFJANG_00502 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HEBFJANG_00503 1.8e-240 agcS E (Alanine) symporter
HEBFJANG_00504 1.3e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEBFJANG_00505 1.4e-104 yfiF3 K sequence-specific DNA binding
HEBFJANG_00506 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
HEBFJANG_00507 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HEBFJANG_00509 1.8e-67 yecS P ABC transporter (Permease
HEBFJANG_00510 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
HEBFJANG_00511 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
HEBFJANG_00512 7.9e-266 dtpT E transporter
HEBFJANG_00514 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
HEBFJANG_00515 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEBFJANG_00516 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEBFJANG_00517 3.4e-61 csm6 S Psort location Cytoplasmic, score
HEBFJANG_00518 1.9e-203 csm5 L CRISPR-associated RAMP protein, Csm5 family
HEBFJANG_00519 1.4e-164 csm4 L CRISPR-associated RAMP protein, Csm4 family
HEBFJANG_00520 1.1e-116 csm3 L RAMP superfamily
HEBFJANG_00521 5.6e-62 csm2 L Pfam:DUF310
HEBFJANG_00522 0.0 csm1 S CRISPR-associated protein Csm1 family
HEBFJANG_00523 1.3e-131 cas6 S CRISPR-associated endoribonuclease Cas6
HEBFJANG_00524 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEBFJANG_00525 1.8e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEBFJANG_00526 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEBFJANG_00527 6.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HEBFJANG_00528 3.2e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HEBFJANG_00529 2.1e-98 S TraX protein
HEBFJANG_00531 1.7e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HEBFJANG_00532 6.5e-266 S Psort location CytoplasmicMembrane, score
HEBFJANG_00533 5.1e-26 dinF V drug transmembrane transporter activity
HEBFJANG_00534 6.3e-12 dinF V Mate efflux family protein
HEBFJANG_00535 9.6e-72 dinF V Mate efflux family protein
HEBFJANG_00536 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
HEBFJANG_00537 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
HEBFJANG_00538 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HEBFJANG_00539 2.6e-143 2.4.2.3 F Phosphorylase superfamily
HEBFJANG_00542 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
HEBFJANG_00543 1.8e-16 S Alpha/beta hydrolase of unknown function (DUF915)
HEBFJANG_00544 6e-08 S Hydrolases of the alpha beta superfamily
HEBFJANG_00545 2.7e-106 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HEBFJANG_00546 8.1e-52 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HEBFJANG_00547 1e-209 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HEBFJANG_00548 1.2e-158 czcD P cation diffusion facilitator family transporter
HEBFJANG_00549 1.2e-97 K Transcriptional regulator, TetR family
HEBFJANG_00551 6.1e-13 L Transposase
HEBFJANG_00552 1e-193 L Transposase
HEBFJANG_00553 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HEBFJANG_00554 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HEBFJANG_00555 6.6e-61 EGP Major facilitator Superfamily
HEBFJANG_00556 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
HEBFJANG_00557 1.3e-212 pqqE C radical SAM domain protein
HEBFJANG_00560 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HEBFJANG_00561 4.1e-53 K peptidyl-tyrosine sulfation
HEBFJANG_00565 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEBFJANG_00566 3.9e-19 IQ Acetoin reductase
HEBFJANG_00567 6.8e-51 IQ Acetoin reductase
HEBFJANG_00568 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEBFJANG_00569 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HEBFJANG_00570 1.9e-152 XK27_05470 E Methionine synthase
HEBFJANG_00571 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEBFJANG_00572 6.9e-251 T PhoQ Sensor
HEBFJANG_00573 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFJANG_00574 5.1e-153 S TraX protein
HEBFJANG_00575 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEBFJANG_00576 2.4e-158 dprA LU DNA protecting protein DprA
HEBFJANG_00577 1.1e-167 GK ROK family
HEBFJANG_00578 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEBFJANG_00579 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEBFJANG_00580 6.9e-127 K DNA-binding helix-turn-helix protein
HEBFJANG_00581 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
HEBFJANG_00582 2.4e-87 niaX
HEBFJANG_00583 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEBFJANG_00584 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEBFJANG_00585 2e-126 gntR1 K transcriptional
HEBFJANG_00586 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HEBFJANG_00587 2.3e-176 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEBFJANG_00588 0.0 res_1 3.1.21.5 S Type III restriction
HEBFJANG_00589 1.1e-20
HEBFJANG_00591 7.4e-110 adhP 1.1.1.1 C alcohol dehydrogenase
HEBFJANG_00592 2.3e-62 adhP 1.1.1.1 C alcohol dehydrogenase
HEBFJANG_00593 3.1e-142 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEBFJANG_00594 1.4e-158 aatB ET ABC transporter substrate-binding protein
HEBFJANG_00595 3.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
HEBFJANG_00596 5.3e-105 artQ P ABC transporter (Permease
HEBFJANG_00597 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
HEBFJANG_00598 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEBFJANG_00599 4.5e-166 cpsY K Transcriptional regulator
HEBFJANG_00600 6.6e-71 L transposition
HEBFJANG_00601 1.9e-119 mur1 NU muramidase
HEBFJANG_00602 1.5e-170 yeiH S Membrane
HEBFJANG_00603 1.7e-08
HEBFJANG_00604 2.1e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
HEBFJANG_00605 3.7e-88 XK27_10720 D peptidase activity
HEBFJANG_00606 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
HEBFJANG_00607 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
HEBFJANG_00608 2.9e-154 glcU U Glucose uptake
HEBFJANG_00609 5.2e-113 hsdM 2.1.1.72 V type I restriction-modification system
HEBFJANG_00610 5.2e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
HEBFJANG_00611 6.3e-54 L Transposase
HEBFJANG_00612 3.3e-98 cysE 2.3.1.30 E serine acetyltransferase
HEBFJANG_00613 3.5e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEBFJANG_00614 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEBFJANG_00615 4.4e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HEBFJANG_00616 0.0 copB 3.6.3.4 P P-type ATPase
HEBFJANG_00617 9.4e-43 K Cold-Shock Protein
HEBFJANG_00618 3.7e-112 L PFAM Integrase, catalytic core
HEBFJANG_00619 3.3e-09 L PFAM Integrase, catalytic core
HEBFJANG_00620 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
HEBFJANG_00621 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
HEBFJANG_00622 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
HEBFJANG_00624 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
HEBFJANG_00625 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HEBFJANG_00627 5.7e-217 S MvaI/BcnI restriction endonuclease family
HEBFJANG_00629 7.7e-13
HEBFJANG_00630 5e-31 S Hypothetical protein (DUF2513)
HEBFJANG_00631 6.5e-31
HEBFJANG_00632 1e-39
HEBFJANG_00637 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
HEBFJANG_00638 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEBFJANG_00639 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
HEBFJANG_00640 3.3e-46 K Putative DNA-binding domain
HEBFJANG_00641 5.4e-32 cspD K Cold shock protein domain
HEBFJANG_00642 5.8e-41 pepD E dipeptidase activity
HEBFJANG_00643 8e-90 pepD E Dipeptidase
HEBFJANG_00644 8.7e-162 whiA K May be required for sporulation
HEBFJANG_00645 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HEBFJANG_00646 1.2e-163 rapZ S Displays ATPase and GTPase activities
HEBFJANG_00647 5.3e-136 yejC S cyclic nucleotide-binding protein
HEBFJANG_00648 4.2e-18 D nuclear chromosome segregation
HEBFJANG_00649 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HEBFJANG_00650 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HEBFJANG_00651 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HEBFJANG_00652 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HEBFJANG_00653 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
HEBFJANG_00654 3e-13
HEBFJANG_00655 2.4e-30
HEBFJANG_00656 1.5e-07
HEBFJANG_00657 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HEBFJANG_00658 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HEBFJANG_00659 3.1e-81 ypmB S Protein conserved in bacteria
HEBFJANG_00660 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HEBFJANG_00661 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HEBFJANG_00662 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
HEBFJANG_00663 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
HEBFJANG_00664 2.7e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HEBFJANG_00665 1.5e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HEBFJANG_00666 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEBFJANG_00667 1.5e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEBFJANG_00668 5.5e-29 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEBFJANG_00669 7.5e-101 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HEBFJANG_00670 1.3e-24 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
HEBFJANG_00671 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
HEBFJANG_00672 2.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
HEBFJANG_00673 2.1e-30 rpsT J rRNA binding
HEBFJANG_00674 9.2e-110 T PhoQ Sensor
HEBFJANG_00675 4.3e-41 T PhoQ Sensor
HEBFJANG_00676 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFJANG_00677 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HEBFJANG_00678 6.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HEBFJANG_00679 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEBFJANG_00680 1.6e-92 panT S ECF transporter, substrate-specific component
HEBFJANG_00681 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HEBFJANG_00682 7.3e-166 metF 1.5.1.20 C reductase
HEBFJANG_00683 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEBFJANG_00685 7.1e-217 sip L Belongs to the 'phage' integrase family
HEBFJANG_00686 6e-39 K Helix-turn-helix
HEBFJANG_00687 5.5e-17 K TRANSCRIPTIONal
HEBFJANG_00692 6.9e-22
HEBFJANG_00693 3e-164 KL Phage plasmid primase P4 family
HEBFJANG_00694 2e-296 S DNA primase
HEBFJANG_00696 2.3e-12
HEBFJANG_00698 2e-103
HEBFJANG_00699 1.4e-66 S tRNA_anti-like
HEBFJANG_00700 4e-22 L Belongs to the 'phage' integrase family
HEBFJANG_00701 3e-44 ymbI L transposase activity
HEBFJANG_00702 2.6e-72 hpaIIR 3.1.21.4 L HpaII restriction endonuclease
HEBFJANG_00703 1.7e-146 2.1.1.37 H cytosine-specific methyltransferase
HEBFJANG_00704 5.1e-106 V Abi-like protein
HEBFJANG_00705 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HEBFJANG_00706 1.1e-151 3.6.3.8 P cation transport ATPase
HEBFJANG_00707 0.0 3.6.3.8 P cation transport ATPase
HEBFJANG_00708 5.2e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEBFJANG_00709 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFJANG_00710 4.6e-238 dltB M Membrane protein involved in D-alanine export
HEBFJANG_00711 9.3e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFJANG_00712 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
HEBFJANG_00713 0.0 XK27_10035 V abc transporter atp-binding protein
HEBFJANG_00714 0.0 yfiB1 V abc transporter atp-binding protein
HEBFJANG_00715 2.4e-107 pvaA M lytic transglycosylase activity
HEBFJANG_00716 6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
HEBFJANG_00717 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEBFJANG_00718 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEBFJANG_00719 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEBFJANG_00720 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEBFJANG_00721 4.5e-111 tdk 2.7.1.21 F thymidine kinase
HEBFJANG_00722 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HEBFJANG_00723 8.9e-155 gst O Glutathione S-transferase
HEBFJANG_00724 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HEBFJANG_00725 1.9e-175 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEBFJANG_00726 2e-45 rpmE2 J 50S ribosomal protein L31
HEBFJANG_00727 8.8e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
HEBFJANG_00729 3.2e-45 L Transposase
HEBFJANG_00730 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEBFJANG_00731 3.3e-134 divIVA D Cell division protein DivIVA
HEBFJANG_00732 4.7e-143 ylmH T S4 RNA-binding domain
HEBFJANG_00733 8.8e-35 yggT D integral membrane protein
HEBFJANG_00734 2e-95 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEBFJANG_00735 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEBFJANG_00736 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEBFJANG_00737 1.1e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEBFJANG_00738 6.9e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEBFJANG_00739 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEBFJANG_00740 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEBFJANG_00742 0.0 typA T GTP-binding protein TypA
HEBFJANG_00743 1.6e-177 glk 2.7.1.2 G Glucokinase
HEBFJANG_00744 8.4e-28 yqgQ S protein conserved in bacteria
HEBFJANG_00745 1.1e-80 perR P Belongs to the Fur family
HEBFJANG_00746 1.6e-91 dps P Belongs to the Dps family
HEBFJANG_00747 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HEBFJANG_00748 1.4e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HEBFJANG_00749 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HEBFJANG_00750 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HEBFJANG_00751 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HEBFJANG_00752 6.2e-56 S Domain of unknown function (DUF4430)
HEBFJANG_00753 5.1e-73 S Psort location CytoplasmicMembrane, score
HEBFJANG_00754 1.8e-135 htpX O Belongs to the peptidase M48B family
HEBFJANG_00755 1.5e-92 lemA S LemA family
HEBFJANG_00756 8.8e-157 spd F DNA RNA non-specific endonuclease
HEBFJANG_00757 3e-38
HEBFJANG_00758 2.5e-44
HEBFJANG_00760 9.3e-68 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
HEBFJANG_00761 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
HEBFJANG_00762 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
HEBFJANG_00763 1.4e-44 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFJANG_00764 8.3e-76 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEBFJANG_00765 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
HEBFJANG_00766 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
HEBFJANG_00767 1.4e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEBFJANG_00768 2.1e-27 P Hemerythrin HHE cation binding domain protein
HEBFJANG_00769 2.2e-144 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
HEBFJANG_00770 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEBFJANG_00771 5.1e-116 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
HEBFJANG_00772 9.8e-174 S hydrolase
HEBFJANG_00773 5.9e-16
HEBFJANG_00774 1.5e-154 M LysM domain
HEBFJANG_00775 1.9e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HEBFJANG_00776 1.2e-33 S SIR2-like domain
HEBFJANG_00777 5.2e-29 S SIR2-like domain
HEBFJANG_00778 1.2e-224 mutH L DNA mismatch repair enzyme MutH
HEBFJANG_00779 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HEBFJANG_00780 4.8e-11
HEBFJANG_00781 7.3e-234 mntH P H( )-stimulated, divalent metal cation uptake system
HEBFJANG_00782 1.1e-33 XK27_12190 S protein conserved in bacteria
HEBFJANG_00784 8.4e-88 bioY S biotin synthase
HEBFJANG_00785 8.1e-46 S CHY zinc finger
HEBFJANG_00786 3.4e-252 yegQ O Peptidase U32
HEBFJANG_00787 2e-177 yegQ O Peptidase U32
HEBFJANG_00789 5.5e-69 ytxH S General stress protein
HEBFJANG_00791 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEBFJANG_00792 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEBFJANG_00793 9.9e-42 pspC KT PspC domain
HEBFJANG_00794 0.0 yhgF K Transcriptional accessory protein
HEBFJANG_00796 1.2e-155 XK27_03015 S permease
HEBFJANG_00797 2.3e-145 ycgQ S TIGR03943 family
HEBFJANG_00798 9e-195 S CRISPR-associated protein Csn2 subfamily St
HEBFJANG_00799 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEBFJANG_00800 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEBFJANG_00801 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HEBFJANG_00802 1.1e-94
HEBFJANG_00803 4.8e-33 estA E GDSL-like Lipase/Acylhydrolase
HEBFJANG_00804 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HEBFJANG_00805 1e-31 K Cro/C1-type HTH DNA-binding domain
HEBFJANG_00806 1.2e-45
HEBFJANG_00807 8.9e-20
HEBFJANG_00808 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEBFJANG_00809 4.5e-97 mip S hydroperoxide reductase activity
HEBFJANG_00810 7e-203 I acyl-CoA dehydrogenase
HEBFJANG_00811 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
HEBFJANG_00812 6.4e-252 msrR K Transcriptional regulator
HEBFJANG_00813 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
HEBFJANG_00814 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEBFJANG_00815 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEBFJANG_00816 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HEBFJANG_00817 3.2e-53 yheA S Belongs to the UPF0342 family
HEBFJANG_00818 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HEBFJANG_00819 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEBFJANG_00820 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEBFJANG_00821 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEBFJANG_00822 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEBFJANG_00823 2e-219 ywbD 2.1.1.191 J Methyltransferase
HEBFJANG_00824 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEBFJANG_00825 2e-25 WQ51_00785
HEBFJANG_00826 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEBFJANG_00827 1e-78 yueI S Protein of unknown function (DUF1694)
HEBFJANG_00828 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HEBFJANG_00829 6.6e-101 yyaQ V Protein conserved in bacteria
HEBFJANG_00830 2.8e-28 yyaQ S YjbR
HEBFJANG_00831 4.4e-183 ccpA K Catabolite control protein A
HEBFJANG_00832 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HEBFJANG_00833 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HEBFJANG_00834 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEBFJANG_00835 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HEBFJANG_00836 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEBFJANG_00837 2e-33 secG U Preprotein translocase subunit SecG
HEBFJANG_00838 2.5e-220 mdtG EGP Major facilitator Superfamily
HEBFJANG_00839 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEBFJANG_00840 7.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEBFJANG_00841 8.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEBFJANG_00842 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HEBFJANG_00843 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEBFJANG_00844 6.8e-53 licT K transcriptional antiterminator
HEBFJANG_00845 5.8e-64 licT K transcriptional antiterminator
HEBFJANG_00846 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEBFJANG_00847 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HEBFJANG_00848 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEBFJANG_00849 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEBFJANG_00850 7.5e-23 I Alpha/beta hydrolase family
HEBFJANG_00851 1.5e-35 yugF I carboxylic ester hydrolase activity
HEBFJANG_00852 2.2e-45 K sequence-specific DNA binding
HEBFJANG_00853 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HEBFJANG_00855 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HEBFJANG_00856 3.1e-78 feoA P FeoA domain protein
HEBFJANG_00857 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
HEBFJANG_00858 3.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HEBFJANG_00859 1.3e-34 ykuJ S protein conserved in bacteria
HEBFJANG_00860 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEBFJANG_00861 0.0 clpE O Belongs to the ClpA ClpB family
HEBFJANG_00862 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HEBFJANG_00863 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
HEBFJANG_00864 1.2e-65 S oxidoreductase
HEBFJANG_00865 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
HEBFJANG_00866 3.7e-70 M Pfam SNARE associated Golgi protein
HEBFJANG_00867 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
HEBFJANG_00868 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
HEBFJANG_00871 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
HEBFJANG_00874 4.8e-16 S Protein of unknown function (DUF2969)
HEBFJANG_00875 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
HEBFJANG_00876 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEBFJANG_00877 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEBFJANG_00878 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEBFJANG_00879 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
HEBFJANG_00880 1.4e-29 S Domain of unknown function (DUF1912)
HEBFJANG_00881 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HEBFJANG_00882 1.5e-250 mmuP E amino acid
HEBFJANG_00883 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HEBFJANG_00884 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEBFJANG_00885 9.7e-22
HEBFJANG_00886 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEBFJANG_00887 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEBFJANG_00888 1.7e-218 mvaS 2.3.3.10 I synthase
HEBFJANG_00889 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HEBFJANG_00890 1e-25 K hmm pf08876
HEBFJANG_00891 1.1e-116 yqfA K protein, Hemolysin III
HEBFJANG_00892 1.6e-22 S Protein of unknown function (DUF3114)
HEBFJANG_00893 1.1e-161 S Protein of unknown function (DUF3114)
HEBFJANG_00894 1.6e-70 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEBFJANG_00895 2.3e-57 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEBFJANG_00896 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEBFJANG_00897 5.5e-49 XK27_13030
HEBFJANG_00898 1.2e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HEBFJANG_00899 4.4e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HEBFJANG_00900 4.2e-68 U protein secretion
HEBFJANG_00901 3e-29 U protein secretion
HEBFJANG_00903 1.7e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEBFJANG_00904 2.5e-21
HEBFJANG_00905 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HEBFJANG_00906 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEBFJANG_00907 2.4e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEBFJANG_00908 1e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
HEBFJANG_00909 1.4e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HEBFJANG_00910 7.9e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HEBFJANG_00911 8.8e-104 GBS0088 J protein conserved in bacteria
HEBFJANG_00912 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEBFJANG_00913 1.3e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HEBFJANG_00914 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
HEBFJANG_00915 7e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HEBFJANG_00916 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEBFJANG_00917 2.5e-113 S VIT family
HEBFJANG_00918 6.5e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
HEBFJANG_00919 1.9e-22
HEBFJANG_00920 8e-28 XK27_00085 K Transcriptional
HEBFJANG_00921 6.9e-197 yceA S Belongs to the UPF0176 family
HEBFJANG_00922 5.4e-122 sagI S ABC-2 type transporter
HEBFJANG_00923 2.8e-168 V ABC transporter
HEBFJANG_00924 2.5e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEBFJANG_00925 2.5e-132 rr02 KT response regulator
HEBFJANG_00926 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HEBFJANG_00927 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEBFJANG_00928 1.3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEBFJANG_00929 0.0 lmrA V abc transporter atp-binding protein
HEBFJANG_00930 0.0 mdlB V abc transporter atp-binding protein
HEBFJANG_00932 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEBFJANG_00933 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEBFJANG_00934 7.2e-24 ytrF V efflux transmembrane transporter activity
HEBFJANG_00935 4.6e-43 V efflux transmembrane transporter activity
HEBFJANG_00936 1.7e-59 V permease protein
HEBFJANG_00937 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEBFJANG_00938 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEBFJANG_00939 5.1e-131 2.1.1.223 S Putative SAM-dependent methyltransferase
HEBFJANG_00940 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HEBFJANG_00941 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HEBFJANG_00942 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HEBFJANG_00943 3.7e-227 pyrP F uracil Permease
HEBFJANG_00944 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEBFJANG_00945 2.9e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEBFJANG_00946 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEBFJANG_00947 1.4e-167 fhuR K transcriptional regulator (lysR family)
HEBFJANG_00953 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEBFJANG_00954 1.4e-75 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
HEBFJANG_00955 9.4e-119 pts33BCA G pts system
HEBFJANG_00956 5.8e-71 pts33BCA G pts system
HEBFJANG_00957 4.8e-24 pts33BCA G pts system
HEBFJANG_00958 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
HEBFJANG_00959 1.8e-254 cycA E permease
HEBFJANG_00960 4.5e-39 ynzC S UPF0291 protein
HEBFJANG_00961 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HEBFJANG_00962 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HEBFJANG_00963 1.7e-32 S membrane
HEBFJANG_00964 1.2e-61
HEBFJANG_00965 4.4e-26
HEBFJANG_00966 7.4e-55
HEBFJANG_00967 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEBFJANG_00968 1.5e-114 nptA P COG1283 Na phosphate symporter
HEBFJANG_00969 2.9e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HEBFJANG_00970 9.2e-105 mur1 NU mannosyl-glycoprotein
HEBFJANG_00971 1.2e-52 glnB K Belongs to the P(II) protein family
HEBFJANG_00972 2.9e-232 amt P Ammonium Transporter
HEBFJANG_00973 4.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEBFJANG_00974 9.5e-55 yabA L Involved in initiation control of chromosome replication
HEBFJANG_00975 1.2e-135 yaaT S stage 0 sporulation protein
HEBFJANG_00976 6.4e-162 holB 2.7.7.7 L dna polymerase iii
HEBFJANG_00977 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEBFJANG_00978 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEBFJANG_00979 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEBFJANG_00980 2.8e-230 ftsW D Belongs to the SEDS family
HEBFJANG_00981 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HEBFJANG_00982 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEBFJANG_00983 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEBFJANG_00984 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEBFJANG_00985 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEBFJANG_00986 3.3e-78 atpF C ATP synthase F(0) sector subunit b
HEBFJANG_00987 2.4e-114 atpB C it plays a direct role in the translocation of protons across the membrane
HEBFJANG_00988 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEBFJANG_00989 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEBFJANG_00990 5.9e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEBFJANG_00991 8e-51 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HEBFJANG_00992 8.9e-14 coiA 3.6.4.12 S Competence protein
HEBFJANG_00993 2.9e-15 T peptidase
HEBFJANG_00994 1.4e-151 rarD S Transporter
HEBFJANG_00995 6.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEBFJANG_00996 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HEBFJANG_00997 2.2e-130 yxkH G deacetylase
HEBFJANG_00998 1.4e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HEBFJANG_00999 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HEBFJANG_01000 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEBFJANG_01001 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEBFJANG_01002 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HEBFJANG_01003 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEBFJANG_01004 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
HEBFJANG_01005 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HEBFJANG_01006 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HEBFJANG_01007 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEBFJANG_01008 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HEBFJANG_01009 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
HEBFJANG_01010 0.0 pepF E oligoendopeptidase F
HEBFJANG_01011 1.4e-186 coiA 3.6.4.12 S Competence protein
HEBFJANG_01012 1.8e-164 K transcriptional regulator (lysR family)
HEBFJANG_01013 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEBFJANG_01017 8e-191 phoH T phosphate starvation-inducible protein PhoH
HEBFJANG_01018 2.3e-61 rlpA M LysM domain protein
HEBFJANG_01019 1.5e-123 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
HEBFJANG_01020 7.4e-35 yozE S Belongs to the UPF0346 family
HEBFJANG_01021 1.7e-159 cvfB S Protein conserved in bacteria
HEBFJANG_01022 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEBFJANG_01023 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HEBFJANG_01024 1.3e-120 sptS 2.7.13.3 T Histidine kinase
HEBFJANG_01025 1.4e-45 K Acetyltransferase (GNAT) family
HEBFJANG_01026 0.0 lmrA2 V abc transporter atp-binding protein
HEBFJANG_01027 0.0 lmrA1 V abc transporter atp-binding protein
HEBFJANG_01028 1.9e-77 K DNA-binding transcription factor activity
HEBFJANG_01029 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HEBFJANG_01030 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEBFJANG_01031 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HEBFJANG_01032 6.5e-77 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HEBFJANG_01033 7.2e-25 U response to pH
HEBFJANG_01034 0.0 yfmR S abc transporter atp-binding protein
HEBFJANG_01035 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEBFJANG_01036 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEBFJANG_01037 9.8e-91 XK27_08360 S EDD domain protein, DegV family
HEBFJANG_01038 2.6e-64 WQ51_03320 S cog cog4835
HEBFJANG_01039 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HEBFJANG_01040 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HEBFJANG_01041 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HEBFJANG_01042 6.4e-29 2.3.1.128 K acetyltransferase
HEBFJANG_01043 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HEBFJANG_01044 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HEBFJANG_01045 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEBFJANG_01046 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HEBFJANG_01048 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HEBFJANG_01049 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEBFJANG_01050 0.0 fruA 2.7.1.202 G phosphotransferase system
HEBFJANG_01051 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HEBFJANG_01052 5.5e-122 fruR K transcriptional
HEBFJANG_01053 8.9e-84 L Transposase
HEBFJANG_01054 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
HEBFJANG_01055 6.6e-38 L transposase activity
HEBFJANG_01056 8.4e-155 L COG2801 Transposase and inactivated derivatives
HEBFJANG_01057 1.1e-113 K sequence-specific DNA binding
HEBFJANG_01058 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
HEBFJANG_01059 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
HEBFJANG_01060 7.7e-198 V (ABC) transporter
HEBFJANG_01061 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
HEBFJANG_01062 1.1e-176 S Protein of unknown function (DUF3114)
HEBFJANG_01063 2.7e-82 S Protein of unknown function (DUF3114)
HEBFJANG_01065 1.1e-65 tnp L Transposase
HEBFJANG_01066 4.7e-27 L Transposase and inactivated derivatives, TnpA family
HEBFJANG_01067 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
HEBFJANG_01068 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HEBFJANG_01069 1.1e-65 tnp L Transposase
HEBFJANG_01070 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEBFJANG_01071 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HEBFJANG_01072 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEBFJANG_01073 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HEBFJANG_01074 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEBFJANG_01075 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEBFJANG_01076 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEBFJANG_01077 1.6e-126 IQ reductase
HEBFJANG_01078 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HEBFJANG_01079 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HEBFJANG_01080 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEBFJANG_01081 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEBFJANG_01082 4e-72 marR K Transcriptional regulator, MarR family
HEBFJANG_01083 6.9e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HEBFJANG_01084 1.6e-114 S Haloacid dehalogenase-like hydrolase
HEBFJANG_01085 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
HEBFJANG_01086 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
HEBFJANG_01087 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEBFJANG_01088 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
HEBFJANG_01089 1.3e-101 ygaC J Belongs to the UPF0374 family
HEBFJANG_01090 6.4e-108 S Domain of unknown function (DUF1803)
HEBFJANG_01091 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
HEBFJANG_01099 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEBFJANG_01100 1.7e-122 comFC S Competence protein
HEBFJANG_01101 5.9e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HEBFJANG_01102 1.1e-110 yvyE 3.4.13.9 S YigZ family
HEBFJANG_01103 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEBFJANG_01104 8.9e-41 acuB S IMP dehydrogenase activity
HEBFJANG_01105 6.8e-69 acuB S IMP dehydrogenase activity
HEBFJANG_01106 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HEBFJANG_01107 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HEBFJANG_01108 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
HEBFJANG_01109 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
HEBFJANG_01110 1.3e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HEBFJANG_01111 7.1e-46 ylbG S UPF0298 protein
HEBFJANG_01112 1.2e-74 ylbF S Belongs to the UPF0342 family
HEBFJANG_01113 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEBFJANG_01114 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEBFJANG_01117 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HEBFJANG_01118 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
HEBFJANG_01119 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HEBFJANG_01120 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HEBFJANG_01121 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEBFJANG_01122 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HEBFJANG_01123 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HEBFJANG_01124 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
HEBFJANG_01125 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
HEBFJANG_01126 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEBFJANG_01127 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEBFJANG_01128 1.4e-41 ylxQ J ribosomal protein
HEBFJANG_01129 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HEBFJANG_01130 3.1e-212 nusA K Participates in both transcription termination and antitermination
HEBFJANG_01131 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
HEBFJANG_01132 2.5e-220 brpA K Transcriptional
HEBFJANG_01133 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
HEBFJANG_01134 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HEBFJANG_01135 2.5e-248 pbuO S permease
HEBFJANG_01136 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HEBFJANG_01137 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HEBFJANG_01138 1.1e-181 manL 2.7.1.191 G pts system
HEBFJANG_01139 5e-108 manM G pts system
HEBFJANG_01140 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
HEBFJANG_01141 4.2e-62 manO S protein conserved in bacteria
HEBFJANG_01142 8e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEBFJANG_01143 1.4e-32 M the current gene model (or a revised gene model) may contain a
HEBFJANG_01145 2.6e-94 L Integrase core domain
HEBFJANG_01146 1.4e-36 L Integrase core domain
HEBFJANG_01147 2.6e-49 3.2.1.4 GH5,GH9 M domain protein
HEBFJANG_01148 2.1e-12 G gluconolactonase activity
HEBFJANG_01149 1.3e-125 tnp L DDE domain
HEBFJANG_01150 5.9e-17 lytN 3.5.1.104 M LysM domain
HEBFJANG_01151 2.8e-160 L Transposase DDE domain
HEBFJANG_01152 4.3e-41 L Protein of unknown function (DUF3991)
HEBFJANG_01154 2.3e-42 L transposase activity
HEBFJANG_01155 5e-23 L Transposase
HEBFJANG_01156 2.5e-23 L Transposase
HEBFJANG_01157 1.7e-54 L transposition
HEBFJANG_01158 1.8e-85 L PFAM Integrase catalytic region
HEBFJANG_01159 9e-88 yrdC 3.5.1.19 Q isochorismatase
HEBFJANG_01160 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HEBFJANG_01161 4e-167 dnaI L Primosomal protein DnaI
HEBFJANG_01162 5e-218 dnaB L Replication initiation and membrane attachment
HEBFJANG_01163 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEBFJANG_01164 3.3e-275 T PhoQ Sensor
HEBFJANG_01165 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFJANG_01166 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
HEBFJANG_01167 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HEBFJANG_01168 1.4e-243 P COG0168 Trk-type K transport systems, membrane components
HEBFJANG_01169 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
HEBFJANG_01170 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
HEBFJANG_01171 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEBFJANG_01172 1.2e-146 cbiQ P cobalt transport
HEBFJANG_01173 0.0 ykoD P abc transporter atp-binding protein
HEBFJANG_01174 8e-94 S UPF0397 protein
HEBFJANG_01175 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HEBFJANG_01176 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HEBFJANG_01177 5.2e-98 metI P ABC transporter (Permease
HEBFJANG_01178 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEBFJANG_01179 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HEBFJANG_01180 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HEBFJANG_01181 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HEBFJANG_01182 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
HEBFJANG_01183 1.8e-153 ET amino acid transport
HEBFJANG_01184 3.8e-205 EGP Transmembrane secretion effector
HEBFJANG_01185 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
HEBFJANG_01186 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFJANG_01187 5.3e-153 ET amino acid transport
HEBFJANG_01188 1.6e-131 cbiO P ABC transporter
HEBFJANG_01189 1.1e-136 P cobalt transport protein
HEBFJANG_01190 4.3e-175 cbiM P PDGLE domain
HEBFJANG_01191 3.4e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HEBFJANG_01192 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HEBFJANG_01193 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HEBFJANG_01194 6.6e-78 ureE O enzyme active site formation
HEBFJANG_01195 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HEBFJANG_01196 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HEBFJANG_01197 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HEBFJANG_01198 6.8e-95 ureI S AmiS/UreI family transporter
HEBFJANG_01199 2.1e-105 S Domain of unknown function (DUF4173)
HEBFJANG_01200 1.8e-50 yhaI L Membrane
HEBFJANG_01201 2.3e-129 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HEBFJANG_01202 1.8e-34 V protein secretion by the type I secretion system
HEBFJANG_01203 1.2e-54 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HEBFJANG_01204 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HEBFJANG_01205 1.2e-32 V protein secretion by the type I secretion system
HEBFJANG_01206 5.6e-161 K sequence-specific DNA binding
HEBFJANG_01207 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HEBFJANG_01208 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEBFJANG_01209 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEBFJANG_01210 1.3e-246 trkA P Potassium transporter peripheral membrane component
HEBFJANG_01211 1.2e-258 trkH P Cation transport protein
HEBFJANG_01212 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HEBFJANG_01213 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEBFJANG_01214 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEBFJANG_01215 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEBFJANG_01216 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HEBFJANG_01217 7.8e-85 ykuL S CBS domain
HEBFJANG_01218 3.5e-99 XK27_09740 S Phosphoesterase
HEBFJANG_01219 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEBFJANG_01220 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HEBFJANG_01221 7.6e-36 yneF S UPF0154 protein
HEBFJANG_01222 3.7e-91 K transcriptional regulator
HEBFJANG_01223 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEBFJANG_01226 8.8e-98 ybhL S Belongs to the BI1 family
HEBFJANG_01227 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HEBFJANG_01228 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEBFJANG_01229 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HEBFJANG_01230 8.5e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEBFJANG_01231 5.2e-59 L Integrase core domain protein
HEBFJANG_01232 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEBFJANG_01233 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEBFJANG_01234 2.1e-82 XK27_09675 K -acetyltransferase
HEBFJANG_01235 5.7e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HEBFJANG_01236 2.5e-23
HEBFJANG_01237 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HEBFJANG_01238 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HEBFJANG_01239 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HEBFJANG_01240 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEBFJANG_01241 8.9e-95 ypsA S Belongs to the UPF0398 family
HEBFJANG_01242 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEBFJANG_01243 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEBFJANG_01244 4.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEBFJANG_01245 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HEBFJANG_01246 4.1e-09 S Domain of unknown function (DUF4651)
HEBFJANG_01247 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HEBFJANG_01248 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEBFJANG_01249 2.6e-68 yeeE S Sulphur transport
HEBFJANG_01250 2e-109 yeeE S Sulphur transport
HEBFJANG_01251 1.9e-36 yeeD O sulfur carrier activity
HEBFJANG_01252 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEBFJANG_01253 1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEBFJANG_01256 4.1e-158 rrmA 2.1.1.187 Q methyltransferase
HEBFJANG_01257 1.5e-64 S phosphatase activity
HEBFJANG_01258 1.9e-46 S glycolate biosynthetic process
HEBFJANG_01259 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEBFJANG_01260 1.3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEBFJANG_01261 8.5e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEBFJANG_01262 7.5e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HEBFJANG_01263 1.6e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEBFJANG_01264 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HEBFJANG_01265 1.3e-83 XK27_08585 S Psort location CytoplasmicMembrane, score
HEBFJANG_01266 2.5e-116 fnt P Formate nitrite transporter
HEBFJANG_01267 1.5e-220 XK27_09615 C reductase
HEBFJANG_01268 6.2e-76 XK27_09620 S reductase
HEBFJANG_01269 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
HEBFJANG_01270 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HEBFJANG_01271 1.8e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEBFJANG_01272 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
HEBFJANG_01273 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
HEBFJANG_01274 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HEBFJANG_01275 3.8e-205 EGP Transmembrane secretion effector
HEBFJANG_01276 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
HEBFJANG_01277 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEBFJANG_01278 1.1e-30 ET amino acid transport
HEBFJANG_01279 5.1e-259 pepC 3.4.22.40 E aminopeptidase
HEBFJANG_01280 1.9e-77 yhaI L Membrane
HEBFJANG_01281 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEBFJANG_01282 1.3e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEBFJANG_01283 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
HEBFJANG_01284 2.6e-76 S thiolester hydrolase activity
HEBFJANG_01286 3.8e-40 K transcriptional
HEBFJANG_01288 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEBFJANG_01289 1.6e-137 glcR K transcriptional regulator (DeoR family)
HEBFJANG_01290 6.2e-35 cof Q phosphatase activity
HEBFJANG_01291 6e-55 cof Q phosphatase activity
HEBFJANG_01292 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HEBFJANG_01293 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HEBFJANG_01294 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
HEBFJANG_01295 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEBFJANG_01296 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEBFJANG_01297 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEBFJANG_01298 6.8e-56 S TM2 domain
HEBFJANG_01299 4.7e-43
HEBFJANG_01301 1.4e-33 L Integrase core domain protein
HEBFJANG_01302 1.7e-51 L transposition
HEBFJANG_01303 3.2e-10 L transposase activity
HEBFJANG_01304 4.4e-37 L Transposase
HEBFJANG_01305 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEBFJANG_01306 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEBFJANG_01307 5.2e-142 cmpC S abc transporter atp-binding protein
HEBFJANG_01308 0.0 WQ51_06230 S ABC transporter substrate binding protein
HEBFJANG_01309 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEBFJANG_01310 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HEBFJANG_01311 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
HEBFJANG_01312 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEBFJANG_01313 9.8e-50 yajC U protein transport
HEBFJANG_01314 1.9e-127 yeeN K transcriptional regulatory protein
HEBFJANG_01315 1.1e-256 pgi 5.3.1.9 G Belongs to the GPI family
HEBFJANG_01316 6.6e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
HEBFJANG_01317 4.8e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEBFJANG_01318 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
HEBFJANG_01319 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
HEBFJANG_01320 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HEBFJANG_01321 1.6e-127 adcB P ABC transporter (Permease
HEBFJANG_01322 8.3e-136 adcC P ABC transporter, ATP-binding protein
HEBFJANG_01323 3.1e-72 adcR K transcriptional
HEBFJANG_01324 9.4e-223 EGP Major facilitator Superfamily
HEBFJANG_01325 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEBFJANG_01326 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEBFJANG_01327 6.4e-23
HEBFJANG_01328 3.4e-62 oppF P Belongs to the ABC transporter superfamily
HEBFJANG_01329 7.5e-62 oppF P Belongs to the ABC transporter superfamily
HEBFJANG_01330 2.7e-41 oppD P Belongs to the ABC transporter superfamily
HEBFJANG_01331 1.2e-62 oppD P Belongs to the ABC transporter superfamily
HEBFJANG_01332 2.5e-32 oppD P Belongs to the ABC transporter superfamily
HEBFJANG_01333 3e-27 oppD P Belongs to the ABC transporter superfamily
HEBFJANG_01334 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFJANG_01335 2.5e-09 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFJANG_01336 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFJANG_01337 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFJANG_01338 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEBFJANG_01339 2e-138 oppA E ABC transporter substrate-binding protein
HEBFJANG_01340 7e-10 oppA E ABC transporter substrate-binding protein
HEBFJANG_01341 2.2e-273 sufB O assembly protein SufB
HEBFJANG_01342 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
HEBFJANG_01343 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEBFJANG_01344 6.3e-235 sufD O assembly protein SufD
HEBFJANG_01345 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HEBFJANG_01346 5.5e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
HEBFJANG_01347 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HEBFJANG_01348 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEBFJANG_01349 5.8e-275 glnP P ABC transporter
HEBFJANG_01350 1e-123 glnQ E abc transporter atp-binding protein
HEBFJANG_01351 5e-94 V VanZ like family
HEBFJANG_01352 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEBFJANG_01353 6.5e-202 yhjX P Major Facilitator
HEBFJANG_01354 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HEBFJANG_01355 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEBFJANG_01356 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEBFJANG_01357 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HEBFJANG_01358 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HEBFJANG_01359 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HEBFJANG_01360 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HEBFJANG_01361 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEBFJANG_01362 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEBFJANG_01363 3.8e-81 nrdI F Belongs to the NrdI family
HEBFJANG_01364 6.3e-186 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HEBFJANG_01365 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HEBFJANG_01366 1.4e-42 F nucleotide catabolic process
HEBFJANG_01367 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEBFJANG_01368 2e-177 prmA J Ribosomal protein L11 methyltransferase
HEBFJANG_01369 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HEBFJANG_01370 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
HEBFJANG_01371 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEBFJANG_01372 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEBFJANG_01373 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEBFJANG_01374 4.6e-149 ykuT M mechanosensitive ion channel
HEBFJANG_01375 1.6e-77 sigH K DNA-templated transcription, initiation
HEBFJANG_01376 6.5e-87
HEBFJANG_01377 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HEBFJANG_01378 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HEBFJANG_01379 9.9e-19 S Domain of unknown function (DUF4649)
HEBFJANG_01380 2.5e-169 L Transposase
HEBFJANG_01381 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HEBFJANG_01384 1.7e-60 hmpT S membrane
HEBFJANG_01385 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HEBFJANG_01386 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEBFJANG_01387 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEBFJANG_01388 9.8e-298 dnaK O Heat shock 70 kDa protein
HEBFJANG_01389 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEBFJANG_01390 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEBFJANG_01391 1.3e-102 acmA 3.2.1.17 NU amidase activity
HEBFJANG_01392 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HEBFJANG_01393 2.2e-38 ais G alpha-ribazole phosphatase activity
HEBFJANG_01394 1.9e-242 XK27_08635 S UPF0210 protein
HEBFJANG_01395 3.6e-39 gcvR T UPF0237 protein
HEBFJANG_01396 3.3e-225 capA M Bacterial capsule synthesis protein
HEBFJANG_01397 5.7e-91 tnp L Transposase
HEBFJANG_01398 3.4e-75 isp2 S pathogenesis
HEBFJANG_01400 4.9e-173
HEBFJANG_01401 1.8e-38 S Helix-turn-helix domain
HEBFJANG_01402 2.2e-224 int L Belongs to the 'phage' integrase family
HEBFJANG_01404 0.0 res_1 3.1.21.5 S Type III restriction
HEBFJANG_01405 9.7e-227 sthIM 2.1.1.72 L DNA methylase
HEBFJANG_01408 5.3e-18 D FtsK/SpoIIIE family
HEBFJANG_01409 1.3e-134 D ftsk spoiiie
HEBFJANG_01411 1.3e-154
HEBFJANG_01412 1.7e-22
HEBFJANG_01413 9.3e-184 L Phage integrase family
HEBFJANG_01414 6.5e-90 3.6.4.12 K Divergent AAA domain protein
HEBFJANG_01415 5.9e-24 3.6.4.12
HEBFJANG_01416 2.5e-183 EGP Major facilitator Superfamily
HEBFJANG_01417 2.4e-231 spaC2 V Lanthionine synthetase C family protein
HEBFJANG_01418 0.0 S Lantibiotic dehydratase, C terminus
HEBFJANG_01420 1.5e-35 K sequence-specific DNA binding
HEBFJANG_01421 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HEBFJANG_01422 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEBFJANG_01423 3.6e-57 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEBFJANG_01424 1.6e-94 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEBFJANG_01425 2.3e-31 K helix-turn-helix
HEBFJANG_01426 3.4e-155 degV S DegV family
HEBFJANG_01427 3.5e-91 yacP S RNA-binding protein containing a PIN domain
HEBFJANG_01428 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEBFJANG_01431 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEBFJANG_01432 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEBFJANG_01433 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
HEBFJANG_01434 4.5e-143 S SseB protein N-terminal domain
HEBFJANG_01435 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEBFJANG_01436 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HEBFJANG_01437 4.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HEBFJANG_01438 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HEBFJANG_01439 0.0 clpC O Belongs to the ClpA ClpB family
HEBFJANG_01440 2.4e-75 ctsR K Belongs to the CtsR family
HEBFJANG_01441 1.1e-83 S Putative small multi-drug export protein
HEBFJANG_01442 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEBFJANG_01443 6.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HEBFJANG_01446 1.9e-86 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HEBFJANG_01447 7.3e-22 yocD 3.4.17.13 V carboxypeptidase activity
HEBFJANG_01448 3.2e-40 L transposition
HEBFJANG_01449 1e-87 L Integrase core domain protein
HEBFJANG_01450 1.7e-96 S reductase
HEBFJANG_01451 1.8e-26 badR K DNA-binding transcription factor activity
HEBFJANG_01452 5.5e-36 XK27_02060 S Transglycosylase associated protein
HEBFJANG_01453 5.7e-222 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HEBFJANG_01454 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEBFJANG_01459 1.9e-07
HEBFJANG_01462 2.6e-10
HEBFJANG_01467 1.1e-65 spxA_2 1.20.4.1 P Belongs to the ArsC family
HEBFJANG_01468 2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEBFJANG_01469 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
HEBFJANG_01470 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HEBFJANG_01471 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEBFJANG_01473 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEBFJANG_01475 1.2e-61 KT phosphorelay signal transduction system
HEBFJANG_01476 7e-34 S Protein of unknown function (DUF3021)
HEBFJANG_01477 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEBFJANG_01478 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HEBFJANG_01479 8.2e-70 argR K Regulates arginine biosynthesis genes
HEBFJANG_01480 2.6e-09 L Transposase
HEBFJANG_01481 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HEBFJANG_01482 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEBFJANG_01483 9.2e-141 1.1.1.169 H Ketopantoate reductase
HEBFJANG_01484 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEBFJANG_01485 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEBFJANG_01486 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
HEBFJANG_01487 2.3e-161 S CHAP domain
HEBFJANG_01488 4.8e-76 L transposase activity
HEBFJANG_01489 1.2e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HEBFJANG_01490 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEBFJANG_01491 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HEBFJANG_01492 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEBFJANG_01493 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEBFJANG_01494 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HEBFJANG_01495 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEBFJANG_01496 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEBFJANG_01497 1e-142 recO L Involved in DNA repair and RecF pathway recombination
HEBFJANG_01498 2.9e-218 araT 2.6.1.1 E Aminotransferase
HEBFJANG_01499 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEBFJANG_01500 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
HEBFJANG_01501 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HEBFJANG_01502 5.5e-139 mreC M Involved in formation and maintenance of cell shape
HEBFJANG_01508 5.3e-11
HEBFJANG_01516 5.5e-74 L Integrase core domain protein
HEBFJANG_01517 9.2e-51 S Protein of unknown function (DUF3397)
HEBFJANG_01518 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEBFJANG_01519 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEBFJANG_01520 7.3e-69 amiA E transmembrane transport
HEBFJANG_01521 6.7e-81 amiA E transmembrane transport
HEBFJANG_01522 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEBFJANG_01523 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEBFJANG_01524 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
HEBFJANG_01525 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEBFJANG_01526 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEBFJANG_01527 2e-186 jag S RNA-binding protein
HEBFJANG_01528 1e-13 rpmH J Ribosomal protein L34
HEBFJANG_01529 1.1e-83 L Transposase
HEBFJANG_01530 6.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEBFJANG_01532 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
HEBFJANG_01533 2e-09 L thioesterase
HEBFJANG_01534 1.9e-141 S Macro domain protein
HEBFJANG_01535 1.1e-50 trxA O Belongs to the thioredoxin family
HEBFJANG_01536 1.6e-143 tatD L Hydrolase, tatd
HEBFJANG_01537 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEBFJANG_01538 6.2e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEBFJANG_01540 4.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEBFJANG_01541 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HEBFJANG_01542 2.4e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
HEBFJANG_01543 6.9e-173 rmuC S RmuC domain protein
HEBFJANG_01544 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
HEBFJANG_01545 5.3e-142 purR 2.4.2.7 F operon repressor
HEBFJANG_01546 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEBFJANG_01547 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEBFJANG_01548 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEBFJANG_01549 1.8e-187 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEBFJANG_01550 1.9e-86 L Integrase core domain protein
HEBFJANG_01551 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HEBFJANG_01552 3.1e-30
HEBFJANG_01553 1.5e-12
HEBFJANG_01554 1.3e-87 S Fusaric acid resistance protein-like
HEBFJANG_01555 8.5e-63 glnR K Transcriptional regulator
HEBFJANG_01556 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
HEBFJANG_01557 2.7e-40 pscB M CHAP domain protein
HEBFJANG_01558 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEBFJANG_01559 2.5e-33 ykzG S Belongs to the UPF0356 family
HEBFJANG_01560 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HEBFJANG_01561 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEBFJANG_01562 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEBFJANG_01563 1.8e-114 azlC E AzlC protein
HEBFJANG_01564 8.8e-48 azlD E branched-chain amino acid
HEBFJANG_01565 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEBFJANG_01566 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HEBFJANG_01567 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEBFJANG_01568 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEBFJANG_01569 1e-93 cvpA S toxin biosynthetic process
HEBFJANG_01570 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEBFJANG_01571 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEBFJANG_01576 2.5e-230 mutY L A G-specific adenine glycosylase
HEBFJANG_01577 3.6e-41 XK27_05745
HEBFJANG_01578 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HEBFJANG_01579 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEBFJANG_01580 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEBFJANG_01582 3.1e-124 XK27_01040 S Pfam PF06570
HEBFJANG_01583 2e-169 corA P COG0598 Mg2 and Co2 transporters
HEBFJANG_01584 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HEBFJANG_01587 7.7e-11 V 'abc transporter, ATP-binding protein
HEBFJANG_01590 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HEBFJANG_01591 1.1e-83 comEB 3.5.4.12 F ComE operon protein 2
HEBFJANG_01592 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEBFJANG_01593 3.4e-62 yqhY S protein conserved in bacteria
HEBFJANG_01594 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEBFJANG_01595 1.7e-179 scrR K Transcriptional
HEBFJANG_01596 4.1e-291 scrB 3.2.1.26 GH32 G invertase
HEBFJANG_01597 0.0 scrA 2.7.1.211 G pts system
HEBFJANG_01598 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HEBFJANG_01599 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEBFJANG_01601 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEBFJANG_01602 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HEBFJANG_01603 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HEBFJANG_01604 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEBFJANG_01605 1.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEBFJANG_01606 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEBFJANG_01607 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HEBFJANG_01608 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
HEBFJANG_01609 2.9e-18 yebC M Membrane
HEBFJANG_01610 1.6e-79 yebC M Membrane
HEBFJANG_01611 3.5e-17 KT response to antibiotic
HEBFJANG_01612 8.5e-68 KT response to antibiotic
HEBFJANG_01613 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
HEBFJANG_01614 3.4e-57 liaI S membrane
HEBFJANG_01615 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HEBFJANG_01616 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HEBFJANG_01617 9.3e-122 S Protein of unknown function (DUF554)
HEBFJANG_01618 2.1e-129 ecsA_2 V abc transporter atp-binding protein
HEBFJANG_01619 9.2e-284 XK27_00765
HEBFJANG_01620 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEBFJANG_01621 6.9e-210 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEBFJANG_01622 4.5e-18 D nuclear chromosome segregation
HEBFJANG_01623 2.8e-21 yhaI J Protein of unknown function (DUF805)
HEBFJANG_01624 3.4e-58
HEBFJANG_01625 2.2e-85
HEBFJANG_01626 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEBFJANG_01627 8.1e-46 ftsL D cell division protein FtsL
HEBFJANG_01628 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HEBFJANG_01629 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEBFJANG_01630 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEBFJANG_01632 4.8e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HEBFJANG_01633 2.4e-66 yutD J protein conserved in bacteria
HEBFJANG_01634 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEBFJANG_01635 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
HEBFJANG_01637 0.0 mdlA V abc transporter atp-binding protein
HEBFJANG_01638 0.0 mdlB V abc transporter atp-binding protein
HEBFJANG_01639 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HEBFJANG_01640 4e-235 mesE M Transport protein ComB
HEBFJANG_01642 1.4e-237 blpH 2.7.13.3 T protein histidine kinase activity
HEBFJANG_01643 4.4e-132 agrA KT phosphorelay signal transduction system
HEBFJANG_01646 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
HEBFJANG_01651 1.2e-165 L integrase core domain
HEBFJANG_01652 3.9e-122 L Transposase
HEBFJANG_01653 6.7e-98 blpT
HEBFJANG_01654 2.9e-28 blpT
HEBFJANG_01655 3e-47 spiA K sequence-specific DNA binding
HEBFJANG_01658 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HEBFJANG_01659 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HEBFJANG_01660 5e-44 V CAAX protease self-immunity
HEBFJANG_01661 4.6e-140 cppA E CppA N-terminal
HEBFJANG_01662 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HEBFJANG_01663 4.4e-115 ybbL S abc transporter atp-binding protein
HEBFJANG_01664 1.5e-127 ybbM S transport system, permease component
HEBFJANG_01665 1.4e-33 D nuclear chromosome segregation
HEBFJANG_01666 7.2e-46 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
HEBFJANG_01667 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEBFJANG_01668 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
HEBFJANG_01669 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HEBFJANG_01670 1.3e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEBFJANG_01672 8.8e-153 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HEBFJANG_01673 1.4e-159 yxeN P ABC transporter (Permease
HEBFJANG_01674 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
HEBFJANG_01675 6.1e-08 S Protein of unknown function (DUF4059)
HEBFJANG_01676 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEBFJANG_01677 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
HEBFJANG_01678 2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEBFJANG_01679 8.4e-196 ylbL T Belongs to the peptidase S16 family
HEBFJANG_01680 1.3e-184 yhcC S radical SAM protein
HEBFJANG_01681 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
HEBFJANG_01683 0.0 yjcE P NhaP-type Na H and K H antiporters
HEBFJANG_01684 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HEBFJANG_01685 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HEBFJANG_01686 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEBFJANG_01689 2.4e-75 XK27_03180 T universal stress protein
HEBFJANG_01690 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HEBFJANG_01691 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HEBFJANG_01692 3.4e-100 pncA Q isochorismatase
HEBFJANG_01693 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
HEBFJANG_01694 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEBFJANG_01695 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEBFJANG_01696 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEBFJANG_01697 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HEBFJANG_01698 9.8e-25 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
HEBFJANG_01699 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEBFJANG_01700 1.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEBFJANG_01701 8.7e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEBFJANG_01702 4e-59
HEBFJANG_01703 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEBFJANG_01704 1.8e-98 yqeG S hydrolase of the HAD superfamily
HEBFJANG_01705 2.4e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HEBFJANG_01706 3.5e-49 yhbY J RNA-binding protein
HEBFJANG_01707 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEBFJANG_01708 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HEBFJANG_01709 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEBFJANG_01710 2e-140 yqeM Q Methyltransferase domain protein
HEBFJANG_01711 1.2e-202 ylbM S Belongs to the UPF0348 family
HEBFJANG_01712 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
HEBFJANG_01713 6.5e-55
HEBFJANG_01714 4.8e-11
HEBFJANG_01715 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HEBFJANG_01716 2.3e-133 ecsA V abc transporter atp-binding protein
HEBFJANG_01717 1.6e-183 ecsB U ABC transporter
HEBFJANG_01718 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
HEBFJANG_01719 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEBFJANG_01721 7.7e-227 ytfP S Flavoprotein
HEBFJANG_01722 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HEBFJANG_01723 7.4e-64 XK27_02560 S cog cog2151
HEBFJANG_01724 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
HEBFJANG_01725 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
HEBFJANG_01726 5.3e-119 K transcriptional regulator, MerR family
HEBFJANG_01727 5.1e-47 L transposase activity
HEBFJANG_01728 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEBFJANG_01729 6.1e-27
HEBFJANG_01730 0.0 ctpE P E1-E2 ATPase
HEBFJANG_01731 1.6e-55
HEBFJANG_01732 1.5e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEBFJANG_01733 2.3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HEBFJANG_01734 1.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEBFJANG_01735 1.9e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HEBFJANG_01736 3e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HEBFJANG_01737 2.1e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEBFJANG_01738 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEBFJANG_01739 2.7e-73 copY K Copper transport repressor, CopY TcrY family
HEBFJANG_01740 0.0 copA 3.6.3.54 P P-type ATPase
HEBFJANG_01741 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
HEBFJANG_01742 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HEBFJANG_01743 6e-115 papP P ABC transporter (Permease
HEBFJANG_01744 3e-106 P ABC transporter (Permease
HEBFJANG_01745 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
HEBFJANG_01746 1.1e-155 cjaA ET ABC transporter substrate-binding protein
HEBFJANG_01750 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEBFJANG_01751 7.9e-120 ywaF S Integral membrane protein (intg_mem_TP0381)
HEBFJANG_01752 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HEBFJANG_01753 1.6e-200 yjbB G Permeases of the major facilitator superfamily
HEBFJANG_01754 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HEBFJANG_01755 7.8e-100 thiT S Thiamine transporter
HEBFJANG_01756 1.9e-62 yjqA S Bacterial PH domain
HEBFJANG_01757 2.3e-154 corA P CorA-like protein
HEBFJANG_01758 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEBFJANG_01760 1e-41 yazA L endonuclease containing a URI domain
HEBFJANG_01761 2.3e-139 yabB 2.1.1.223 L Methyltransferase
HEBFJANG_01762 4.1e-22 nodB3 G polysaccharide deacetylase
HEBFJANG_01763 1.7e-77 nodB3 G polysaccharide deacetylase
HEBFJANG_01764 8.3e-142 plsC 2.3.1.51 I Acyltransferase
HEBFJANG_01765 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HEBFJANG_01766 0.0 comEC S Competence protein ComEC
HEBFJANG_01767 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEBFJANG_01768 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HEBFJANG_01769 3.3e-231 ytoI K transcriptional regulator containing CBS domains
HEBFJANG_01770 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HEBFJANG_01771 7.4e-164 rbn E Belongs to the UPF0761 family
HEBFJANG_01772 3.7e-85 ccl S cog cog4708
HEBFJANG_01773 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEBFJANG_01774 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEBFJANG_01775 1.9e-55 L Transposase
HEBFJANG_01776 2.1e-74 S QueT transporter
HEBFJANG_01777 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HEBFJANG_01778 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HEBFJANG_01779 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HEBFJANG_01780 4.1e-37 ylqC L Belongs to the UPF0109 family
HEBFJANG_01781 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HEBFJANG_01782 0.0 ydaO E amino acid
HEBFJANG_01783 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
HEBFJANG_01784 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEBFJANG_01785 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HEBFJANG_01786 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEBFJANG_01787 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEBFJANG_01788 7.8e-171 murB 1.3.1.98 M cell wall formation
HEBFJANG_01789 6.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HEBFJANG_01790 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
HEBFJANG_01791 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
HEBFJANG_01792 2.3e-206 potD P spermidine putrescine ABC transporter
HEBFJANG_01793 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
HEBFJANG_01794 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
HEBFJANG_01795 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
HEBFJANG_01796 2.6e-95 GK ROK family
HEBFJANG_01797 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEBFJANG_01798 3.9e-104 wecD M Acetyltransferase GNAT family
HEBFJANG_01799 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEBFJANG_01800 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HEBFJANG_01801 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
HEBFJANG_01803 2.2e-58 lrgA S Effector of murein hydrolase LrgA
HEBFJANG_01804 2.2e-117 lrgB M effector of murein hydrolase
HEBFJANG_01805 2.6e-109 3.1.3.18 S IA, variant 1
HEBFJANG_01806 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEBFJANG_01807 2.8e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEBFJANG_01808 7.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
HEBFJANG_01809 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HEBFJANG_01810 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEBFJANG_01811 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEBFJANG_01812 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
HEBFJANG_01814 8.5e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
HEBFJANG_01816 6.6e-30 ycaO O OsmC-like protein
HEBFJANG_01817 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
HEBFJANG_01820 3.6e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEBFJANG_01822 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEBFJANG_01823 2.4e-16 XK27_00735
HEBFJANG_01824 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HEBFJANG_01825 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HEBFJANG_01826 2.6e-32 S CAAX amino terminal protease family protein
HEBFJANG_01827 1.2e-55 V CAAX protease self-immunity
HEBFJANG_01829 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEBFJANG_01830 2.9e-84 mutT 3.6.1.55 F Nudix family
HEBFJANG_01831 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
HEBFJANG_01832 7.2e-136 ET ABC transporter
HEBFJANG_01833 3.4e-200 arcT 2.6.1.1 E Aminotransferase
HEBFJANG_01834 7.9e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
HEBFJANG_01835 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HEBFJANG_01836 1.1e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEBFJANG_01837 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEBFJANG_01838 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEBFJANG_01839 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HEBFJANG_01840 5.4e-251 M Psort location CytoplasmicMembrane, score
HEBFJANG_01841 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HEBFJANG_01842 1.2e-231
HEBFJANG_01843 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEBFJANG_01844 7.6e-126 ycbB S Glycosyl transferase family 2
HEBFJANG_01845 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
HEBFJANG_01846 2.6e-220 amrA S polysaccharide biosynthetic process
HEBFJANG_01847 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
HEBFJANG_01848 1.3e-226 rgpA GT4 M Domain of unknown function (DUF1972)
HEBFJANG_01849 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
HEBFJANG_01850 1.1e-142 rgpC GM Transport permease protein
HEBFJANG_01851 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEBFJANG_01852 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEBFJANG_01853 0.0 rgpF M Rhamnan synthesis protein F
HEBFJANG_01854 6.2e-120 radC E Belongs to the UPF0758 family
HEBFJANG_01855 1.6e-131 puuD T peptidase C26
HEBFJANG_01856 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEBFJANG_01857 9e-59 XK27_04120 S Putative amino acid metabolism
HEBFJANG_01858 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
HEBFJANG_01859 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEBFJANG_01860 5.8e-103 yjbK S Adenylate cyclase
HEBFJANG_01861 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HEBFJANG_01862 1.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEBFJANG_01863 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HEBFJANG_01864 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HEBFJANG_01865 3.7e-38 L transposase activity
HEBFJANG_01866 1.4e-38 L transposase activity
HEBFJANG_01867 9.3e-29 L transposition
HEBFJANG_01868 4e-110 L PFAM Integrase catalytic region
HEBFJANG_01869 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
HEBFJANG_01870 2e-21 tatD L hydrolase, TatD family'
HEBFJANG_01871 5.5e-23 oppF P Belongs to the ABC transporter superfamily
HEBFJANG_01872 1.2e-24 oppF P Belongs to the ABC transporter superfamily
HEBFJANG_01873 4.1e-158 L COG2801 Transposase and inactivated derivatives
HEBFJANG_01874 8.1e-45 L Transposase
HEBFJANG_01875 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HEBFJANG_01876 1.1e-270 amiC P ABC transporter (Permease
HEBFJANG_01877 2.4e-167 amiD P ABC transporter (Permease
HEBFJANG_01878 2.2e-204 oppD P Belongs to the ABC transporter superfamily
HEBFJANG_01879 4.3e-172 oppF P Belongs to the ABC transporter superfamily
HEBFJANG_01880 9e-131 V ATPase activity
HEBFJANG_01881 9.8e-121 skfE V abc transporter atp-binding protein
HEBFJANG_01882 8.6e-63 yvoA_1 K Transcriptional
HEBFJANG_01883 5.3e-147 supH S overlaps another CDS with the same product name
HEBFJANG_01884 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
HEBFJANG_01885 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEBFJANG_01886 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HEBFJANG_01887 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HEBFJANG_01888 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEBFJANG_01889 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEBFJANG_01890 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEBFJANG_01891 9e-133 stp 3.1.3.16 T phosphatase
HEBFJANG_01892 1.7e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
HEBFJANG_01893 9.1e-119 yvqF KT membrane
HEBFJANG_01894 1.9e-173 vraS 2.7.13.3 T Histidine kinase
HEBFJANG_01895 8.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEBFJANG_01898 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEBFJANG_01899 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HEBFJANG_01900 8.6e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HEBFJANG_01901 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HEBFJANG_01902 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HEBFJANG_01903 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HEBFJANG_01904 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HEBFJANG_01905 6.4e-62 L Transposase
HEBFJANG_01906 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HEBFJANG_01907 4.3e-40 V abc transporter atp-binding protein
HEBFJANG_01908 2.5e-101 V abc transporter atp-binding protein
HEBFJANG_01909 5.1e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HEBFJANG_01910 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HEBFJANG_01911 1.2e-25 L transposition
HEBFJANG_01912 2.7e-08 L Integrase core domain protein
HEBFJANG_01913 2.3e-184 galR K Transcriptional regulator
HEBFJANG_01914 3.7e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEBFJANG_01915 1.3e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HEBFJANG_01916 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEBFJANG_01917 2.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HEBFJANG_01918 0.0 lacS G transporter
HEBFJANG_01919 0.0 lacL 3.2.1.23 G -beta-galactosidase
HEBFJANG_01920 1.3e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEBFJANG_01921 0.0 sbcC L ATPase involved in DNA repair
HEBFJANG_01922 1.4e-84
HEBFJANG_01924 1.8e-87 L transposase activity
HEBFJANG_01925 1.4e-150 L Integrase core domain protein
HEBFJANG_01926 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HEBFJANG_01928 5.5e-258 I radical SAM domain protein
HEBFJANG_01929 1.2e-176 EGP Major Facilitator Superfamily
HEBFJANG_01930 3.9e-110 C Fe-S oxidoreductases
HEBFJANG_01932 1.1e-151 V MatE
HEBFJANG_01933 1.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
HEBFJANG_01934 5e-161 hrtB V MacB-like periplasmic core domain
HEBFJANG_01936 0.0 M family 8
HEBFJANG_01937 2.7e-09
HEBFJANG_01938 5.6e-08
HEBFJANG_01939 5.8e-109 MA20_06410 E LysE type translocator
HEBFJANG_01940 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
HEBFJANG_01941 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
HEBFJANG_01942 1e-137
HEBFJANG_01943 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEBFJANG_01944 4.5e-61
HEBFJANG_01946 9.3e-72 S Signal peptide protein, YSIRK family
HEBFJANG_01947 1.4e-54 K response regulator
HEBFJANG_01948 1.1e-37 BP1961 P nitric oxide dioxygenase activity
HEBFJANG_01950 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
HEBFJANG_01951 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEBFJANG_01952 6.8e-161 yvgN C reductase
HEBFJANG_01953 3e-102 yoaK S Protein of unknown function (DUF1275)
HEBFJANG_01954 1.4e-110 drgA C Nitroreductase
HEBFJANG_01955 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEBFJANG_01956 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
HEBFJANG_01957 5.6e-77 ywnA K Transcriptional regulator
HEBFJANG_01958 9.5e-150 1.13.11.2 S glyoxalase
HEBFJANG_01959 5.1e-110 XK27_02070 S nitroreductase
HEBFJANG_01960 4e-227 yfnA E amino acid
HEBFJANG_01962 4.8e-25 csbD K CsbD-like
HEBFJANG_01963 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEBFJANG_01964 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEBFJANG_01965 1.7e-235 brnQ E Component of the transport system for branched-chain amino acids
HEBFJANG_01966 2.2e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEBFJANG_01967 4.5e-247 norM V Multidrug efflux pump
HEBFJANG_01968 2.1e-192 pbuX F xanthine permease
HEBFJANG_01970 3.2e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEBFJANG_01971 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEBFJANG_01972 6.2e-166 T Histidine kinase
HEBFJANG_01973 1.9e-133 macB2 V ABC transporter, ATP-binding protein
HEBFJANG_01974 0.0 V ABC transporter (permease)
HEBFJANG_01975 6.1e-93 XK27_05000 S metal cluster binding
HEBFJANG_01976 2.6e-30 liaI KT membrane
HEBFJANG_01977 1.4e-15 liaI KT membrane
HEBFJANG_01978 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
HEBFJANG_01979 3.7e-122 S An automated process has identified a potential problem with this gene model

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)