ORF_ID e_value Gene_name EC_number CAZy COGs Description
HCBLAFCG_00007 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCBLAFCG_00008 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCBLAFCG_00009 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HCBLAFCG_00010 1.6e-287 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HCBLAFCG_00011 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCBLAFCG_00012 9.9e-77 tspO T membrane
HCBLAFCG_00013 2.8e-204 cotI S Spore coat protein
HCBLAFCG_00014 2.6e-216 cotSA M Glycosyl transferases group 1
HCBLAFCG_00015 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
HCBLAFCG_00017 6.1e-235 ytcC M Glycosyltransferase Family 4
HCBLAFCG_00018 2.5e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HCBLAFCG_00019 2.1e-241 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCBLAFCG_00020 1.9e-152 galU 2.7.7.9 M Nucleotidyl transferase
HCBLAFCG_00021 2.6e-132 dksA T COG1734 DnaK suppressor protein
HCBLAFCG_00022 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
HCBLAFCG_00023 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HCBLAFCG_00024 6.7e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HCBLAFCG_00025 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HCBLAFCG_00026 7.4e-272 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HCBLAFCG_00027 1.2e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HCBLAFCG_00028 9.7e-169 troA P Belongs to the bacterial solute-binding protein 9 family
HCBLAFCG_00029 8e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HCBLAFCG_00030 1.1e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HCBLAFCG_00031 4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HCBLAFCG_00032 1.1e-24 S Domain of Unknown Function (DUF1540)
HCBLAFCG_00033 1.2e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HCBLAFCG_00034 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
HCBLAFCG_00035 6.1e-41 rpmE2 J Ribosomal protein L31
HCBLAFCG_00036 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HCBLAFCG_00037 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCBLAFCG_00038 2.4e-72 ytkA S YtkA-like
HCBLAFCG_00040 2.1e-76 dps P Belongs to the Dps family
HCBLAFCG_00041 5.4e-63 ytkC S Bacteriophage holin family
HCBLAFCG_00042 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HCBLAFCG_00043 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCBLAFCG_00044 1.4e-144 ytlC P ABC transporter
HCBLAFCG_00045 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HCBLAFCG_00046 1.4e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HCBLAFCG_00047 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HCBLAFCG_00048 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HCBLAFCG_00049 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCBLAFCG_00050 0.0 asnB 6.3.5.4 E Asparagine synthase
HCBLAFCG_00051 4.6e-247 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HCBLAFCG_00052 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HCBLAFCG_00053 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HCBLAFCG_00054 1.8e-214 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HCBLAFCG_00055 7.4e-106 ytqB J Putative rRNA methylase
HCBLAFCG_00056 4e-189 yhcC S Fe-S oxidoreductase
HCBLAFCG_00057 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HCBLAFCG_00059 5.1e-66 ytrA K GntR family transcriptional regulator
HCBLAFCG_00060 4.2e-161 ytrB P abc transporter atp-binding protein
HCBLAFCG_00061 4.9e-150 P ABC-2 family transporter protein
HCBLAFCG_00062 3.7e-126
HCBLAFCG_00063 9.1e-127 ytrE V ABC transporter, ATP-binding protein
HCBLAFCG_00064 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HCBLAFCG_00065 2.8e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_00066 1.6e-185 T PhoQ Sensor
HCBLAFCG_00067 1.1e-138 bceA V ABC transporter, ATP-binding protein
HCBLAFCG_00068 0.0 bceB V ABC transporter (permease)
HCBLAFCG_00069 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HCBLAFCG_00070 1.3e-210 yttB EGP Major facilitator Superfamily
HCBLAFCG_00071 6.6e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HCBLAFCG_00072 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HCBLAFCG_00073 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCBLAFCG_00074 2.1e-51 ytwF P Sulfurtransferase
HCBLAFCG_00075 2.2e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HCBLAFCG_00076 4.4e-144 amyC P ABC transporter (permease)
HCBLAFCG_00077 6.2e-168 amyD P ABC transporter
HCBLAFCG_00078 6.6e-248 msmE G Bacterial extracellular solute-binding protein
HCBLAFCG_00079 1.5e-189 msmR K Transcriptional regulator
HCBLAFCG_00080 7.8e-171 ytaP S Acetyl xylan esterase (AXE1)
HCBLAFCG_00081 4.4e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HCBLAFCG_00082 2.7e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HCBLAFCG_00083 1.6e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HCBLAFCG_00084 2.3e-122 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HCBLAFCG_00085 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HCBLAFCG_00086 1.8e-223 bioI 1.14.14.46 C Cytochrome P450
HCBLAFCG_00087 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HCBLAFCG_00088 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
HCBLAFCG_00089 1.4e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HCBLAFCG_00090 0.0 ytdP K Transcriptional regulator
HCBLAFCG_00091 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HCBLAFCG_00092 5.2e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HCBLAFCG_00093 4.6e-73 yteS G transport
HCBLAFCG_00094 3.7e-248 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HCBLAFCG_00095 5.3e-116 yteU S Integral membrane protein
HCBLAFCG_00096 3.1e-26 yteV S Sporulation protein Cse60
HCBLAFCG_00097 2.2e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HCBLAFCG_00098 1.4e-231 ytfP S HI0933-like protein
HCBLAFCG_00099 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCBLAFCG_00100 1.8e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCBLAFCG_00101 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HCBLAFCG_00102 9e-130 ythP V ABC transporter
HCBLAFCG_00103 1.5e-203 ythQ U Bacterial ABC transporter protein EcsB
HCBLAFCG_00104 2.1e-225 pbuO S permease
HCBLAFCG_00105 1.5e-269 pepV 3.5.1.18 E Dipeptidase
HCBLAFCG_00106 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HCBLAFCG_00107 5.8e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HCBLAFCG_00108 1.3e-165 ytlQ
HCBLAFCG_00109 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HCBLAFCG_00110 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HCBLAFCG_00111 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HCBLAFCG_00112 2e-45 ytzH S YtzH-like protein
HCBLAFCG_00113 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCBLAFCG_00114 8.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HCBLAFCG_00115 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HCBLAFCG_00116 2.2e-51 ytzB S small secreted protein
HCBLAFCG_00117 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HCBLAFCG_00118 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HCBLAFCG_00119 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HCBLAFCG_00120 9.8e-149 ytpQ S Belongs to the UPF0354 family
HCBLAFCG_00121 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCBLAFCG_00122 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HCBLAFCG_00123 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HCBLAFCG_00124 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCBLAFCG_00125 6.6e-17 ytxH S COG4980 Gas vesicle protein
HCBLAFCG_00126 1.7e-54 ytxJ O Protein of unknown function (DUF2847)
HCBLAFCG_00127 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HCBLAFCG_00128 1.7e-182 ccpA K catabolite control protein A
HCBLAFCG_00129 6e-146 motA N flagellar motor
HCBLAFCG_00130 1.4e-125 motS N Flagellar motor protein
HCBLAFCG_00131 5.4e-225 acuC BQ histone deacetylase
HCBLAFCG_00132 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HCBLAFCG_00133 1.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HCBLAFCG_00134 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HCBLAFCG_00135 8.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCBLAFCG_00137 0.0 L DEAD-like helicases superfamily
HCBLAFCG_00138 9.6e-37 L Restriction endonuclease
HCBLAFCG_00139 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCBLAFCG_00140 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HCBLAFCG_00141 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HCBLAFCG_00142 3.4e-109 yttP K Transcriptional regulator
HCBLAFCG_00143 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HCBLAFCG_00144 4.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCBLAFCG_00145 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
HCBLAFCG_00146 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
HCBLAFCG_00147 1.9e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCBLAFCG_00148 2e-29 sspB S spore protein
HCBLAFCG_00149 1e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HCBLAFCG_00150 0.0 ytcJ S amidohydrolase
HCBLAFCG_00151 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCBLAFCG_00152 5.1e-179 sppA OU signal peptide peptidase SppA
HCBLAFCG_00153 8.5e-87 yteJ S RDD family
HCBLAFCG_00154 8.1e-115 ytfI S Protein of unknown function (DUF2953)
HCBLAFCG_00155 8.7e-70 ytfJ S Sporulation protein YtfJ
HCBLAFCG_00156 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCBLAFCG_00157 7e-165 ytxK 2.1.1.72 L DNA methylase
HCBLAFCG_00158 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCBLAFCG_00159 5.7e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HCBLAFCG_00160 3.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCBLAFCG_00161 2.2e-265 argH 4.3.2.1 E argininosuccinate lyase
HCBLAFCG_00163 4.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_00164 1.7e-130 ytkL S Belongs to the UPF0173 family
HCBLAFCG_00165 2.1e-171 ytlI K LysR substrate binding domain
HCBLAFCG_00166 1.4e-98 ytmI K Acetyltransferase (GNAT) domain
HCBLAFCG_00167 2.3e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
HCBLAFCG_00168 3.2e-144 tcyK M Bacterial periplasmic substrate-binding proteins
HCBLAFCG_00169 6.3e-123 tcyL P Binding-protein-dependent transport system inner membrane component
HCBLAFCG_00170 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
HCBLAFCG_00171 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCBLAFCG_00172 1.2e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCBLAFCG_00173 3.5e-45 ytnI O COG0695 Glutaredoxin and related proteins
HCBLAFCG_00174 2.4e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCBLAFCG_00175 1.4e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HCBLAFCG_00176 9e-234 ytnL 3.5.1.47 E hydrolase activity
HCBLAFCG_00177 4.2e-156 ytnM S membrane transporter protein
HCBLAFCG_00178 8e-241 ytoI K transcriptional regulator containing CBS domains
HCBLAFCG_00179 2.4e-47 ytpI S YtpI-like protein
HCBLAFCG_00180 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HCBLAFCG_00181 9.2e-29
HCBLAFCG_00182 8.2e-69 ytrI
HCBLAFCG_00183 3.2e-56 ytrH S Sporulation protein YtrH
HCBLAFCG_00184 0.0 dnaE 2.7.7.7 L DNA polymerase
HCBLAFCG_00185 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HCBLAFCG_00186 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCBLAFCG_00187 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HCBLAFCG_00188 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCBLAFCG_00189 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HCBLAFCG_00190 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HCBLAFCG_00191 2.6e-192 ytvI S sporulation integral membrane protein YtvI
HCBLAFCG_00192 4.7e-71 yeaL S membrane
HCBLAFCG_00193 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HCBLAFCG_00194 1.8e-242 icd 1.1.1.42 C isocitrate
HCBLAFCG_00195 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HCBLAFCG_00196 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_00197 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HCBLAFCG_00198 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCBLAFCG_00199 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCBLAFCG_00200 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HCBLAFCG_00201 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCBLAFCG_00202 8.4e-159 ytbE S reductase
HCBLAFCG_00203 2.5e-201 ytbD EGP Major facilitator Superfamily
HCBLAFCG_00204 9.9e-67 ytcD K Transcriptional regulator
HCBLAFCG_00205 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCBLAFCG_00206 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HCBLAFCG_00207 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCBLAFCG_00208 3.8e-265 dnaB L Membrane attachment protein
HCBLAFCG_00209 1.9e-172 dnaI L Primosomal protein DnaI
HCBLAFCG_00210 1.5e-107 ytxB S SNARE associated Golgi protein
HCBLAFCG_00211 9.3e-158 ytxC S YtxC-like family
HCBLAFCG_00213 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCBLAFCG_00214 2.8e-148 ysaA S HAD-hyrolase-like
HCBLAFCG_00215 0.0 lytS 2.7.13.3 T Histidine kinase
HCBLAFCG_00216 4.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HCBLAFCG_00217 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HCBLAFCG_00218 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HCBLAFCG_00220 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCBLAFCG_00221 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HCBLAFCG_00222 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCBLAFCG_00223 1.7e-44 ysdA S Membrane
HCBLAFCG_00224 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HCBLAFCG_00225 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HCBLAFCG_00226 2.1e-185 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HCBLAFCG_00227 2.7e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HCBLAFCG_00228 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HCBLAFCG_00229 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HCBLAFCG_00230 1.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HCBLAFCG_00231 1.4e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HCBLAFCG_00232 7.6e-252 araN G carbohydrate transport
HCBLAFCG_00233 1.4e-167 araP G carbohydrate transport
HCBLAFCG_00234 9.9e-144 araQ G transport system permease
HCBLAFCG_00235 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HCBLAFCG_00236 0.0 cstA T Carbon starvation protein
HCBLAFCG_00237 1.8e-52 ysfE 4.4.1.5 E Glyoxalase-like domain
HCBLAFCG_00238 5.8e-255 glcF C Glycolate oxidase
HCBLAFCG_00239 9.7e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
HCBLAFCG_00240 3.7e-207 ysfB KT regulator
HCBLAFCG_00241 2.6e-32 sspI S Belongs to the SspI family
HCBLAFCG_00242 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCBLAFCG_00243 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCBLAFCG_00244 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCBLAFCG_00245 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCBLAFCG_00246 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HCBLAFCG_00247 3.9e-85 cvpA S membrane protein, required for colicin V production
HCBLAFCG_00248 0.0 polX L COG1796 DNA polymerase IV (family X)
HCBLAFCG_00249 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCBLAFCG_00250 7.3e-68 yshE S membrane
HCBLAFCG_00251 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCBLAFCG_00252 4e-99 fadR K Transcriptional regulator
HCBLAFCG_00253 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HCBLAFCG_00254 2.2e-134 etfB C Electron transfer flavoprotein
HCBLAFCG_00255 1.3e-176 etfA C Electron transfer flavoprotein
HCBLAFCG_00257 1.7e-303 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HCBLAFCG_00258 2e-52 trxA O Belongs to the thioredoxin family
HCBLAFCG_00259 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCBLAFCG_00260 3.5e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HCBLAFCG_00261 1.2e-79 yslB S Protein of unknown function (DUF2507)
HCBLAFCG_00262 2.4e-107 sdhC C succinate dehydrogenase
HCBLAFCG_00263 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HCBLAFCG_00264 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HCBLAFCG_00265 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HCBLAFCG_00266 1.2e-17 gerE K Transcriptional regulator
HCBLAFCG_00267 1.2e-48 yqaB E IrrE N-terminal-like domain
HCBLAFCG_00268 8.5e-20
HCBLAFCG_00269 9.4e-25 K sequence-specific DNA binding
HCBLAFCG_00270 3.2e-13 K Helix-turn-helix XRE-family like proteins
HCBLAFCG_00272 4.1e-45 S DNA binding
HCBLAFCG_00273 8.6e-83
HCBLAFCG_00278 5.8e-97
HCBLAFCG_00279 3.4e-69 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HCBLAFCG_00280 5.9e-137 xkdC L IstB-like ATP binding protein
HCBLAFCG_00282 1.5e-12 S YopX protein
HCBLAFCG_00283 2.7e-42 S Protein of unknown function (DUF1064)
HCBLAFCG_00284 1.4e-19 yqaO S Phage-like element PBSX protein XtrA
HCBLAFCG_00286 6.4e-56
HCBLAFCG_00288 6.6e-108 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HCBLAFCG_00294 8.9e-71 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HCBLAFCG_00296 1.5e-16 K Transcriptional regulator
HCBLAFCG_00300 3.5e-79 yqaS L DNA packaging
HCBLAFCG_00301 2.6e-185 ps334 S Terminase-like family
HCBLAFCG_00302 1.4e-158 S Phage portal protein, SPP1 Gp6-like
HCBLAFCG_00304 2.7e-63 S Domain of unknown function (DUF4355)
HCBLAFCG_00305 1.9e-111 S Phage capsid family
HCBLAFCG_00307 6.9e-31 S Phage Mu protein F like protein
HCBLAFCG_00308 1.8e-16 S Phage gp6-like head-tail connector protein
HCBLAFCG_00309 1.8e-47
HCBLAFCG_00310 3.1e-23
HCBLAFCG_00311 3.1e-30
HCBLAFCG_00312 2.1e-103 Z012_02110 S Protein of unknown function (DUF3383)
HCBLAFCG_00313 3e-34
HCBLAFCG_00314 7.6e-14
HCBLAFCG_00315 8.2e-131 N phage tail tape measure protein
HCBLAFCG_00316 3e-40 3.5.1.28 M LysM domain
HCBLAFCG_00317 1.4e-30
HCBLAFCG_00318 1e-88
HCBLAFCG_00319 6.1e-23
HCBLAFCG_00320 4.8e-23 S Protein of unknown function (DUF2634)
HCBLAFCG_00321 3e-106 Z012_12235 S homolog of phage Mu protein gp47
HCBLAFCG_00322 1.3e-60
HCBLAFCG_00323 2.2e-46 S Domain of unknown function (DUF2479)
HCBLAFCG_00325 1e-14 xkdX
HCBLAFCG_00326 1.1e-27 xhlA S Haemolysin XhlA
HCBLAFCG_00327 2.7e-31 xhlB S SPP1 phage holin
HCBLAFCG_00328 2.8e-103 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HCBLAFCG_00329 7.9e-37 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HCBLAFCG_00330 6.6e-43 S YolD-like protein
HCBLAFCG_00331 1.8e-167 L Recombinase
HCBLAFCG_00332 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HCBLAFCG_00333 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HCBLAFCG_00334 3.8e-196 gerM S COG5401 Spore germination protein
HCBLAFCG_00335 1.2e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HCBLAFCG_00336 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCBLAFCG_00337 1.8e-92 ysnB S Phosphoesterase
HCBLAFCG_00339 1.2e-130 ysnF S protein conserved in bacteria
HCBLAFCG_00340 1.6e-76 ysnE K acetyltransferase
HCBLAFCG_00342 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HCBLAFCG_00343 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HCBLAFCG_00344 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HCBLAFCG_00345 4.6e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HCBLAFCG_00346 3.1e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HCBLAFCG_00347 4.8e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCBLAFCG_00348 1.8e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCBLAFCG_00349 1.1e-186 ysoA H Tetratricopeptide repeat
HCBLAFCG_00350 4.1e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCBLAFCG_00351 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCBLAFCG_00352 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HCBLAFCG_00353 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HCBLAFCG_00354 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HCBLAFCG_00355 5.4e-89 ysxD
HCBLAFCG_00356 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HCBLAFCG_00357 3.6e-146 hemX O cytochrome C
HCBLAFCG_00358 1.5e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HCBLAFCG_00359 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HCBLAFCG_00360 1.1e-181 hemB 4.2.1.24 H Belongs to the ALAD family
HCBLAFCG_00361 9.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HCBLAFCG_00362 3.3e-186 spoVID M stage VI sporulation protein D
HCBLAFCG_00363 1.9e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HCBLAFCG_00364 1.6e-25
HCBLAFCG_00365 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCBLAFCG_00366 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HCBLAFCG_00367 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HCBLAFCG_00368 4.6e-164 spoIIB S Sporulation related domain
HCBLAFCG_00369 2.8e-102 maf D septum formation protein Maf
HCBLAFCG_00370 1e-125 radC E Belongs to the UPF0758 family
HCBLAFCG_00371 1.8e-184 mreB D Rod shape-determining protein MreB
HCBLAFCG_00372 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HCBLAFCG_00373 1.4e-84 mreD M shape-determining protein
HCBLAFCG_00374 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HCBLAFCG_00375 2.5e-144 minD D Belongs to the ParA family
HCBLAFCG_00376 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HCBLAFCG_00377 2e-160 spoIVFB S Stage IV sporulation protein
HCBLAFCG_00378 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HCBLAFCG_00379 5.9e-55 ysxB J ribosomal protein
HCBLAFCG_00380 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HCBLAFCG_00381 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HCBLAFCG_00382 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCBLAFCG_00383 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HCBLAFCG_00384 6.5e-162 pheA 4.2.1.51 E Prephenate dehydratase
HCBLAFCG_00385 3e-93 niaR S small molecule binding protein (contains 3H domain)
HCBLAFCG_00386 8.5e-226 nifS 2.8.1.7 E Cysteine desulfurase
HCBLAFCG_00387 1.7e-301 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HCBLAFCG_00388 1.1e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HCBLAFCG_00389 1.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HCBLAFCG_00390 8.3e-157 safA M spore coat assembly protein SafA
HCBLAFCG_00391 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCBLAFCG_00392 5.5e-127 yebC K transcriptional regulatory protein
HCBLAFCG_00393 5.3e-262 alsT E Sodium alanine symporter
HCBLAFCG_00394 2.3e-51 S Family of unknown function (DUF5412)
HCBLAFCG_00396 1.2e-117 yrzF T serine threonine protein kinase
HCBLAFCG_00397 1.8e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HCBLAFCG_00398 4.5e-252 csbX EGP Major facilitator Superfamily
HCBLAFCG_00399 4.8e-93 bofC S BofC C-terminal domain
HCBLAFCG_00400 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCBLAFCG_00401 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCBLAFCG_00402 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HCBLAFCG_00403 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCBLAFCG_00404 1.2e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCBLAFCG_00405 1.1e-38 yajC U Preprotein translocase subunit YajC
HCBLAFCG_00406 2.2e-73 yrzE S Protein of unknown function (DUF3792)
HCBLAFCG_00407 1.7e-111 yrbG S membrane
HCBLAFCG_00408 9.1e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCBLAFCG_00409 9.4e-49 yrzD S Post-transcriptional regulator
HCBLAFCG_00410 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HCBLAFCG_00411 8.6e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HCBLAFCG_00412 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HCBLAFCG_00413 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HCBLAFCG_00414 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCBLAFCG_00415 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCBLAFCG_00416 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCBLAFCG_00417 1.3e-245 lytH 3.5.1.28 M COG3103 SH3 domain protein
HCBLAFCG_00419 4.1e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
HCBLAFCG_00420 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HCBLAFCG_00421 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HCBLAFCG_00422 1.7e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HCBLAFCG_00423 1.2e-70 cymR K Transcriptional regulator
HCBLAFCG_00424 2.8e-210 iscS 2.8.1.7 E Cysteine desulfurase
HCBLAFCG_00425 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCBLAFCG_00426 1.4e-15 S COG0457 FOG TPR repeat
HCBLAFCG_00427 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCBLAFCG_00428 2.7e-82 yrrD S protein conserved in bacteria
HCBLAFCG_00429 9.8e-31 yrzR
HCBLAFCG_00430 8e-08 S Protein of unknown function (DUF3918)
HCBLAFCG_00431 7.6e-107 glnP P ABC transporter
HCBLAFCG_00432 2.3e-108 gluC P ABC transporter
HCBLAFCG_00433 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
HCBLAFCG_00434 1.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCBLAFCG_00435 1.7e-169 yrrI S AI-2E family transporter
HCBLAFCG_00436 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCBLAFCG_00437 1.7e-41 yrzL S Belongs to the UPF0297 family
HCBLAFCG_00438 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCBLAFCG_00439 1.2e-45 yrzB S Belongs to the UPF0473 family
HCBLAFCG_00440 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCBLAFCG_00441 1.9e-118 yrrM 2.1.1.104 S O-methyltransferase
HCBLAFCG_00442 3.9e-173 yegQ O Peptidase U32
HCBLAFCG_00443 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HCBLAFCG_00444 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HCBLAFCG_00445 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCBLAFCG_00446 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HCBLAFCG_00447 2.5e-60 yrrS S Protein of unknown function (DUF1510)
HCBLAFCG_00448 1e-25 yrzA S Protein of unknown function (DUF2536)
HCBLAFCG_00449 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HCBLAFCG_00450 8e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCBLAFCG_00451 6.8e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HCBLAFCG_00452 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HCBLAFCG_00453 1.8e-34 yrhC S YrhC-like protein
HCBLAFCG_00454 5.4e-78 yrhD S Protein of unknown function (DUF1641)
HCBLAFCG_00455 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HCBLAFCG_00456 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
HCBLAFCG_00458 1.8e-142 focA P Formate nitrite
HCBLAFCG_00461 5.5e-95 yrhH Q methyltransferase
HCBLAFCG_00462 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HCBLAFCG_00463 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HCBLAFCG_00464 1.2e-43 yrhK S YrhK-like protein
HCBLAFCG_00465 0.0 yrhL I Acyltransferase family
HCBLAFCG_00466 1.6e-149 rsiV S Protein of unknown function (DUF3298)
HCBLAFCG_00467 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HCBLAFCG_00469 5.5e-59
HCBLAFCG_00470 6e-29
HCBLAFCG_00471 4.1e-25 cmcI V Cephalosporin hydroxylase
HCBLAFCG_00473 5.5e-07 speE 2.5.1.16 S Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HCBLAFCG_00474 1.8e-88 MA20_36670 EGP Major facilitator Superfamily
HCBLAFCG_00475 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
HCBLAFCG_00476 3.6e-106 yrhP E LysE type translocator
HCBLAFCG_00477 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HCBLAFCG_00478 0.0 levR K PTS system fructose IIA component
HCBLAFCG_00479 5.7e-74 levD 2.7.1.202 G PTS system fructose IIA component
HCBLAFCG_00480 2.4e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HCBLAFCG_00481 1.1e-115 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HCBLAFCG_00482 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HCBLAFCG_00483 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HCBLAFCG_00484 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HCBLAFCG_00485 2.4e-195 adhA 1.1.1.1 C alcohol dehydrogenase
HCBLAFCG_00486 6.3e-70 pcaC 4.1.1.44 S conserved protein, contains double-stranded beta-helix domain
HCBLAFCG_00487 7.4e-47 yraB K helix_turn_helix, mercury resistance
HCBLAFCG_00488 2e-44 rmeD K MerR family transcriptional regulator
HCBLAFCG_00490 2.3e-114 K Transcriptional regulator
HCBLAFCG_00491 1.4e-165 yajO C Aldo/keto reductase family
HCBLAFCG_00492 8e-13 ptsH G phosphocarrier protein HPr
HCBLAFCG_00493 3.6e-48 yraD M Spore coat protein
HCBLAFCG_00494 7.5e-26 yraE
HCBLAFCG_00495 5.5e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HCBLAFCG_00496 6.4e-63 yraF M Spore coat protein
HCBLAFCG_00497 1.3e-35 yraG
HCBLAFCG_00498 2.5e-65 E Glyoxalase-like domain
HCBLAFCG_00499 3.4e-61 T sh3 domain protein
HCBLAFCG_00500 1.7e-60 T sh3 domain protein
HCBLAFCG_00501 4.8e-134 S Alpha beta hydrolase
HCBLAFCG_00502 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCBLAFCG_00503 1.4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HCBLAFCG_00504 1.4e-186 yrpG C Aldo/keto reductase family
HCBLAFCG_00505 9.1e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HCBLAFCG_00506 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HCBLAFCG_00507 1.1e-48 yjbR S YjbR
HCBLAFCG_00508 3e-116 bmrR K helix_turn_helix, mercury resistance
HCBLAFCG_00509 1.5e-98 flr S Flavin reductase like domain
HCBLAFCG_00510 4.8e-123 yrpD S Domain of unknown function, YrpD
HCBLAFCG_00511 9.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HCBLAFCG_00512 1.2e-191 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HCBLAFCG_00513 4.2e-166 aadK G Streptomycin adenylyltransferase
HCBLAFCG_00514 2.4e-89 yrdA S DinB family
HCBLAFCG_00515 1.9e-57 S Protein of unknown function (DUF2568)
HCBLAFCG_00516 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
HCBLAFCG_00517 1.1e-40 yrdF K ribonuclease inhibitor
HCBLAFCG_00518 5.3e-78 bkdR K helix_turn_helix ASNC type
HCBLAFCG_00519 9.6e-138 azlC E AzlC protein
HCBLAFCG_00520 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HCBLAFCG_00521 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
HCBLAFCG_00522 1.5e-161 gltR K LysR substrate binding domain
HCBLAFCG_00523 1.7e-66 yodA S tautomerase
HCBLAFCG_00524 4e-149 czcD P COG1230 Co Zn Cd efflux system component
HCBLAFCG_00525 3.9e-198 trkA P Oxidoreductase
HCBLAFCG_00526 2.8e-157 yrdQ K Transcriptional regulator
HCBLAFCG_00527 1.6e-169 yrdR EG EamA-like transporter family
HCBLAFCG_00528 3.9e-16 S YrzO-like protein
HCBLAFCG_00529 1.8e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HCBLAFCG_00530 5.9e-82 bltD 2.3.1.57 K FR47-like protein
HCBLAFCG_00531 2.3e-210 blt EGP Major facilitator Superfamily
HCBLAFCG_00532 7.1e-147 bltR K helix_turn_helix, mercury resistance
HCBLAFCG_00533 3.2e-106 yrkC G Cupin domain
HCBLAFCG_00534 7.8e-39 yrkD S protein conserved in bacteria
HCBLAFCG_00535 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
HCBLAFCG_00536 4.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
HCBLAFCG_00538 9.3e-206 yrkH P Rhodanese Homology Domain
HCBLAFCG_00539 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
HCBLAFCG_00540 5.4e-112 yrkJ S membrane transporter protein
HCBLAFCG_00541 1.2e-71 K PFAM Periplasmic binding protein LacI transcriptional regulator
HCBLAFCG_00542 6.3e-100 IQ Enoyl-(Acyl carrier protein) reductase
HCBLAFCG_00543 4e-133 G AP endonuclease family 2 C terminus
HCBLAFCG_00544 4.1e-166 iolT EGP Major facilitator Superfamily
HCBLAFCG_00545 1.4e-26 yqaB E IrrE N-terminal-like domain
HCBLAFCG_00547 7.6e-97 adk 2.7.4.3 F adenylate kinase activity
HCBLAFCG_00548 1.7e-88 K Transcriptional regulator PadR-like family
HCBLAFCG_00549 5.8e-160 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HCBLAFCG_00552 1.9e-53 rusA L Endodeoxyribonuclease RusA
HCBLAFCG_00553 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
HCBLAFCG_00554 1.4e-18 wapA M RHS family
HCBLAFCG_00556 1.1e-72 L Transposase
HCBLAFCG_00558 6.1e-28
HCBLAFCG_00559 6.1e-21 ydaT
HCBLAFCG_00562 8.2e-109 S SEC-C Motif Domain Protein
HCBLAFCG_00564 6.3e-34 yqaS L DNA packaging
HCBLAFCG_00565 1.3e-27 S phage terminase, large subunit
HCBLAFCG_00566 3.2e-123 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HCBLAFCG_00568 1.2e-272 L nucleic acid phosphodiester bond hydrolysis
HCBLAFCG_00569 1e-70 K MerR family transcriptional regulator
HCBLAFCG_00570 1.3e-138 yvgN 1.1.1.346 S Reductase
HCBLAFCG_00572 1.4e-156 S Aspartate phosphatase response regulator
HCBLAFCG_00575 2.1e-54 arsR K ArsR family transcriptional regulator
HCBLAFCG_00576 3.7e-65 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBLAFCG_00577 8.7e-182 arsB 1.20.4.1 P Arsenic resistance protein
HCBLAFCG_00578 4e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HCBLAFCG_00579 1.3e-22 L Helix-turn-helix domain of resolvase
HCBLAFCG_00580 4.6e-140 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
HCBLAFCG_00581 4.2e-64 K BetI-type transcriptional repressor, C-terminal
HCBLAFCG_00582 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCBLAFCG_00583 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HCBLAFCG_00584 2.3e-133 yqeB
HCBLAFCG_00585 3.8e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HCBLAFCG_00586 1.8e-105 yqeD S SNARE associated Golgi protein
HCBLAFCG_00587 4.6e-132 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCBLAFCG_00588 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HCBLAFCG_00590 5.3e-95 yqeG S hydrolase of the HAD superfamily
HCBLAFCG_00591 1.2e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HCBLAFCG_00592 2.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCBLAFCG_00593 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HCBLAFCG_00594 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCBLAFCG_00595 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HCBLAFCG_00596 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCBLAFCG_00597 1.9e-138 yqeM Q Methyltransferase
HCBLAFCG_00598 6.7e-145 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCBLAFCG_00599 1.8e-102 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HCBLAFCG_00600 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HCBLAFCG_00601 0.0 comEC S Competence protein ComEC
HCBLAFCG_00602 4.1e-15 S YqzM-like protein
HCBLAFCG_00603 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HCBLAFCG_00604 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HCBLAFCG_00605 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HCBLAFCG_00606 6.9e-223 spoIIP M stage II sporulation protein P
HCBLAFCG_00607 1.1e-53 yqxA S Protein of unknown function (DUF3679)
HCBLAFCG_00608 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCBLAFCG_00609 7.7e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
HCBLAFCG_00610 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCBLAFCG_00611 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCBLAFCG_00612 0.0 dnaK O Heat shock 70 kDa protein
HCBLAFCG_00613 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCBLAFCG_00614 5.4e-175 prmA J Methylates ribosomal protein L11
HCBLAFCG_00615 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCBLAFCG_00616 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HCBLAFCG_00617 2.4e-157 yqeW P COG1283 Na phosphate symporter
HCBLAFCG_00618 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HCBLAFCG_00619 2.5e-61 yqeY S Yqey-like protein
HCBLAFCG_00620 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HCBLAFCG_00621 4.3e-122 yqfA S UPF0365 protein
HCBLAFCG_00622 6e-25 yqfB
HCBLAFCG_00623 2.7e-45 yqfC S sporulation protein YqfC
HCBLAFCG_00624 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HCBLAFCG_00625 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HCBLAFCG_00627 0.0 yqfF S membrane-associated HD superfamily hydrolase
HCBLAFCG_00628 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCBLAFCG_00629 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HCBLAFCG_00630 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HCBLAFCG_00631 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCBLAFCG_00632 8.4e-19 S YqzL-like protein
HCBLAFCG_00633 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
HCBLAFCG_00634 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HCBLAFCG_00635 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HCBLAFCG_00636 4.5e-112 ccpN K CBS domain
HCBLAFCG_00637 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCBLAFCG_00638 4.5e-88 yaiI S Belongs to the UPF0178 family
HCBLAFCG_00639 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCBLAFCG_00640 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCBLAFCG_00641 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HCBLAFCG_00642 1.4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
HCBLAFCG_00643 1.3e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCBLAFCG_00644 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HCBLAFCG_00645 2.9e-14 yqfQ S YqfQ-like protein
HCBLAFCG_00646 1.9e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCBLAFCG_00647 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCBLAFCG_00648 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HCBLAFCG_00649 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HCBLAFCG_00650 1.9e-77 zur P Belongs to the Fur family
HCBLAFCG_00651 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HCBLAFCG_00652 2.8e-61 yqfX S membrane
HCBLAFCG_00653 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HCBLAFCG_00654 8.9e-47 yqfZ M LysM domain
HCBLAFCG_00655 1.5e-130 yqgB S Protein of unknown function (DUF1189)
HCBLAFCG_00656 4e-73 yqgC S protein conserved in bacteria
HCBLAFCG_00657 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HCBLAFCG_00658 2.5e-231 yqgE EGP Major facilitator superfamily
HCBLAFCG_00659 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HCBLAFCG_00660 7.6e-150 pstS P Phosphate
HCBLAFCG_00661 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HCBLAFCG_00662 4.4e-158 pstA P Phosphate transport system permease
HCBLAFCG_00663 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCBLAFCG_00664 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCBLAFCG_00665 1.6e-71 yqzC S YceG-like family
HCBLAFCG_00666 9.2e-51 yqzD
HCBLAFCG_00668 1.6e-194 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HCBLAFCG_00669 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCBLAFCG_00670 3.9e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCBLAFCG_00671 2.5e-09 yqgO
HCBLAFCG_00672 6.9e-236 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HCBLAFCG_00673 3.1e-33 yqgQ S Protein conserved in bacteria
HCBLAFCG_00674 4.4e-180 glcK 2.7.1.2 G Glucokinase
HCBLAFCG_00675 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HCBLAFCG_00676 1.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HCBLAFCG_00677 1.8e-198 yqgU
HCBLAFCG_00678 6.9e-50 yqgV S Thiamine-binding protein
HCBLAFCG_00679 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HCBLAFCG_00680 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HCBLAFCG_00681 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HCBLAFCG_00682 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HCBLAFCG_00684 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HCBLAFCG_00685 2e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HCBLAFCG_00686 1.4e-173 corA P Mg2 transporter protein
HCBLAFCG_00687 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HCBLAFCG_00688 1.1e-173 comGB NU COG1459 Type II secretory pathway, component PulF
HCBLAFCG_00689 1.4e-47 comGC U Required for transformation and DNA binding
HCBLAFCG_00690 9.5e-66 gspH NU protein transport across the cell outer membrane
HCBLAFCG_00691 3.1e-59 comGE
HCBLAFCG_00692 4.1e-46 comGF U Putative Competence protein ComGF
HCBLAFCG_00693 1.2e-43 S ComG operon protein 7
HCBLAFCG_00694 5.2e-26 yqzE S YqzE-like protein
HCBLAFCG_00695 2.6e-52 yqzG S Protein of unknown function (DUF3889)
HCBLAFCG_00696 3.2e-109 yqxM
HCBLAFCG_00697 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HCBLAFCG_00698 8.6e-142 tasA S Cell division protein FtsN
HCBLAFCG_00699 1e-54 sinR K transcriptional
HCBLAFCG_00700 3.6e-24 sinI S Anti-repressor SinI
HCBLAFCG_00701 1.3e-150 yqhG S Bacterial protein YqhG of unknown function
HCBLAFCG_00702 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HCBLAFCG_00703 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HCBLAFCG_00704 1.9e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HCBLAFCG_00705 2e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HCBLAFCG_00706 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HCBLAFCG_00707 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HCBLAFCG_00708 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HCBLAFCG_00709 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
HCBLAFCG_00710 2.2e-61 yqhP
HCBLAFCG_00711 8e-174 yqhQ S Protein of unknown function (DUF1385)
HCBLAFCG_00712 2.3e-93 yqhR S Conserved membrane protein YqhR
HCBLAFCG_00713 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HCBLAFCG_00714 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HCBLAFCG_00715 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCBLAFCG_00716 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HCBLAFCG_00717 4e-170 spoIIIAA S stage III sporulation protein AA
HCBLAFCG_00718 4.1e-84 spoIIIAB S Stage III sporulation protein
HCBLAFCG_00719 7.6e-29 spoIIIAC S stage III sporulation protein AC
HCBLAFCG_00720 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HCBLAFCG_00721 1.3e-197 spoIIIAE S stage III sporulation protein AE
HCBLAFCG_00722 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HCBLAFCG_00723 2.2e-109 spoIIIAG S stage III sporulation protein AG
HCBLAFCG_00724 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HCBLAFCG_00725 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCBLAFCG_00726 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HCBLAFCG_00727 2.1e-67 yqhY S protein conserved in bacteria
HCBLAFCG_00728 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCBLAFCG_00729 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCBLAFCG_00730 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCBLAFCG_00731 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCBLAFCG_00732 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCBLAFCG_00733 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCBLAFCG_00734 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HCBLAFCG_00735 1.1e-77 argR K Regulates arginine biosynthesis genes
HCBLAFCG_00736 5.5e-306 recN L May be involved in recombinational repair of damaged DNA
HCBLAFCG_00737 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HCBLAFCG_00738 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HCBLAFCG_00740 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HCBLAFCG_00741 2.2e-26
HCBLAFCG_00742 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HCBLAFCG_00743 1.4e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCBLAFCG_00744 2.9e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
HCBLAFCG_00745 1.3e-154 hbdA 1.1.1.157 I Dehydrogenase
HCBLAFCG_00746 1.3e-210 mmgC I acyl-CoA dehydrogenase
HCBLAFCG_00747 4.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HCBLAFCG_00748 4.5e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HCBLAFCG_00749 5.1e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HCBLAFCG_00750 2e-33 yqzF S Protein of unknown function (DUF2627)
HCBLAFCG_00751 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HCBLAFCG_00752 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HCBLAFCG_00753 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCBLAFCG_00754 6e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HCBLAFCG_00755 1.1e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCBLAFCG_00756 4.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCBLAFCG_00757 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCBLAFCG_00758 3.2e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCBLAFCG_00759 1.3e-151 bmrR K helix_turn_helix, mercury resistance
HCBLAFCG_00760 5.5e-133 norA EGP Major facilitator Superfamily
HCBLAFCG_00761 2e-53 norA EGP Major facilitator Superfamily
HCBLAFCG_00762 1.2e-163 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HCBLAFCG_00763 9.3e-77 yqiW S Belongs to the UPF0403 family
HCBLAFCG_00764 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
HCBLAFCG_00765 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HCBLAFCG_00766 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCBLAFCG_00767 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
HCBLAFCG_00768 1.4e-98 yqjB S protein conserved in bacteria
HCBLAFCG_00770 6.6e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HCBLAFCG_00771 4.2e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HCBLAFCG_00772 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HCBLAFCG_00773 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
HCBLAFCG_00774 1.5e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCBLAFCG_00775 4.5e-24 yqzJ
HCBLAFCG_00776 1.8e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCBLAFCG_00777 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCBLAFCG_00778 1.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCBLAFCG_00779 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCBLAFCG_00780 3.9e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCBLAFCG_00781 1.8e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HCBLAFCG_00782 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HCBLAFCG_00783 0.0 rocB E arginine degradation protein
HCBLAFCG_00784 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCBLAFCG_00785 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HCBLAFCG_00786 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_00787 5.4e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HCBLAFCG_00788 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HCBLAFCG_00789 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBLAFCG_00791 4.1e-223 yqjV G Major Facilitator Superfamily
HCBLAFCG_00793 1.3e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCBLAFCG_00794 1.7e-49 S YolD-like protein
HCBLAFCG_00795 1.8e-86 yqjY K acetyltransferase
HCBLAFCG_00796 1.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HCBLAFCG_00797 1.1e-192 yqkA K GrpB protein
HCBLAFCG_00798 2.8e-54 yqkB S Belongs to the HesB IscA family
HCBLAFCG_00799 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HCBLAFCG_00800 1.7e-168 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HCBLAFCG_00801 3.7e-12 yqkE S Protein of unknown function (DUF3886)
HCBLAFCG_00802 1.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HCBLAFCG_00804 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HCBLAFCG_00805 4e-220 yqxK 3.6.4.12 L DNA helicase
HCBLAFCG_00806 4.5e-58 ansR K Transcriptional regulator
HCBLAFCG_00807 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HCBLAFCG_00808 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HCBLAFCG_00809 3.1e-235 mleN C Na H antiporter
HCBLAFCG_00810 1.2e-241 mleA 1.1.1.38 C malic enzyme
HCBLAFCG_00811 2.1e-29 yqkK
HCBLAFCG_00812 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HCBLAFCG_00813 2.4e-80 fur P Belongs to the Fur family
HCBLAFCG_00814 1.4e-36 S Protein of unknown function (DUF4227)
HCBLAFCG_00815 2.2e-154 xerD L recombinase XerD
HCBLAFCG_00816 7.5e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HCBLAFCG_00817 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HCBLAFCG_00818 2e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HCBLAFCG_00819 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HCBLAFCG_00820 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HCBLAFCG_00821 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCBLAFCG_00822 9.6e-112 spoVAA S Stage V sporulation protein AA
HCBLAFCG_00823 1e-67 spoVAB S Stage V sporulation protein AB
HCBLAFCG_00824 2.3e-78 spoVAC S stage V sporulation protein AC
HCBLAFCG_00825 9e-192 spoVAD I Stage V sporulation protein AD
HCBLAFCG_00826 2.2e-57 spoVAEB S stage V sporulation protein
HCBLAFCG_00827 1.4e-110 spoVAEA S stage V sporulation protein
HCBLAFCG_00828 1.2e-272 spoVAF EG Stage V sporulation protein AF
HCBLAFCG_00829 5.7e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCBLAFCG_00830 3.6e-149 ypuA S Secreted protein
HCBLAFCG_00831 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCBLAFCG_00836 3e-07
HCBLAFCG_00837 2e-36 S Pfam Transposase IS66
HCBLAFCG_00839 5.6e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HCBLAFCG_00840 5e-96 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HCBLAFCG_00841 7.8e-55 ypuD
HCBLAFCG_00842 7.1e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCBLAFCG_00843 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
HCBLAFCG_00844 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HCBLAFCG_00845 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HCBLAFCG_00846 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBLAFCG_00847 2.7e-91 ypuF S Domain of unknown function (DUF309)
HCBLAFCG_00848 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCBLAFCG_00849 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCBLAFCG_00850 7.6e-97 ypuI S Protein of unknown function (DUF3907)
HCBLAFCG_00851 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HCBLAFCG_00852 3.5e-103 spmA S Spore maturation protein
HCBLAFCG_00853 1.2e-86 spmB S Spore maturation protein
HCBLAFCG_00854 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCBLAFCG_00855 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HCBLAFCG_00856 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HCBLAFCG_00857 4.4e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HCBLAFCG_00858 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_00859 0.0 resE 2.7.13.3 T Histidine kinase
HCBLAFCG_00860 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HCBLAFCG_00861 4.4e-184 rsiX
HCBLAFCG_00862 1.6e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HCBLAFCG_00863 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBLAFCG_00864 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCBLAFCG_00865 4.7e-41 fer C Ferredoxin
HCBLAFCG_00866 7.9e-199 ypbB 5.1.3.1 S protein conserved in bacteria
HCBLAFCG_00867 9.2e-286 recQ 3.6.4.12 L DNA helicase
HCBLAFCG_00868 1.1e-99 ypbD S metal-dependent membrane protease
HCBLAFCG_00869 3.7e-78 ypbE M Lysin motif
HCBLAFCG_00870 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HCBLAFCG_00871 4e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HCBLAFCG_00872 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HCBLAFCG_00873 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCBLAFCG_00874 8.7e-176 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HCBLAFCG_00875 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HCBLAFCG_00876 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HCBLAFCG_00877 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HCBLAFCG_00878 9.5e-110 ypfA M Flagellar protein YcgR
HCBLAFCG_00879 5e-21 S Family of unknown function (DUF5359)
HCBLAFCG_00880 6.8e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HCBLAFCG_00881 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HCBLAFCG_00882 2.7e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCBLAFCG_00883 1e-07 S YpzI-like protein
HCBLAFCG_00884 6.7e-102 yphA
HCBLAFCG_00885 2.5e-161 seaA S YIEGIA protein
HCBLAFCG_00886 7.9e-28 ypzH
HCBLAFCG_00887 1.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HCBLAFCG_00888 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HCBLAFCG_00889 1.6e-18 yphE S Protein of unknown function (DUF2768)
HCBLAFCG_00890 1.3e-136 yphF
HCBLAFCG_00891 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HCBLAFCG_00892 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCBLAFCG_00893 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HCBLAFCG_00894 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HCBLAFCG_00895 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HCBLAFCG_00896 3.3e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HCBLAFCG_00897 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCBLAFCG_00898 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HCBLAFCG_00899 4.2e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HCBLAFCG_00900 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HCBLAFCG_00901 3.2e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HCBLAFCG_00902 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HCBLAFCG_00903 5.6e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCBLAFCG_00904 1.8e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCBLAFCG_00905 1.2e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HCBLAFCG_00906 1.2e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HCBLAFCG_00907 7.6e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCBLAFCG_00908 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCBLAFCG_00909 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HCBLAFCG_00910 4.4e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HCBLAFCG_00911 2.2e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCBLAFCG_00912 2.7e-233 S COG0457 FOG TPR repeat
HCBLAFCG_00913 8.1e-99 ypiB S Belongs to the UPF0302 family
HCBLAFCG_00914 4.2e-77 ypiF S Protein of unknown function (DUF2487)
HCBLAFCG_00915 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HCBLAFCG_00916 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HCBLAFCG_00917 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HCBLAFCG_00918 6.8e-99 ypjA S membrane
HCBLAFCG_00919 2.3e-142 ypjB S sporulation protein
HCBLAFCG_00920 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HCBLAFCG_00921 2e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HCBLAFCG_00922 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCBLAFCG_00923 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HCBLAFCG_00924 6.9e-130 bshB1 S proteins, LmbE homologs
HCBLAFCG_00925 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HCBLAFCG_00926 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCBLAFCG_00927 2.5e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCBLAFCG_00928 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HCBLAFCG_00929 1.2e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HCBLAFCG_00930 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HCBLAFCG_00931 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HCBLAFCG_00932 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HCBLAFCG_00933 4.9e-79 ypmB S protein conserved in bacteria
HCBLAFCG_00934 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HCBLAFCG_00935 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HCBLAFCG_00936 5.7e-129 dnaD L DNA replication protein DnaD
HCBLAFCG_00937 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCBLAFCG_00938 4.7e-93 ypoC
HCBLAFCG_00939 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HCBLAFCG_00940 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCBLAFCG_00941 2.6e-188 yppC S Protein of unknown function (DUF2515)
HCBLAFCG_00944 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HCBLAFCG_00946 1.2e-48 yppG S YppG-like protein
HCBLAFCG_00947 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HCBLAFCG_00948 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HCBLAFCG_00949 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HCBLAFCG_00950 1.3e-237 yprB L RNase_H superfamily
HCBLAFCG_00951 3.3e-92 ypsA S Belongs to the UPF0398 family
HCBLAFCG_00952 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCBLAFCG_00953 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HCBLAFCG_00955 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HCBLAFCG_00956 2.1e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_00957 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HCBLAFCG_00958 3.9e-187 ptxS K transcriptional
HCBLAFCG_00959 2.4e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HCBLAFCG_00960 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HCBLAFCG_00961 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HCBLAFCG_00962 9.3e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HCBLAFCG_00963 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCBLAFCG_00964 8.9e-63 pbuX F xanthine
HCBLAFCG_00966 2e-57
HCBLAFCG_00973 8.8e-44
HCBLAFCG_00974 6.9e-229
HCBLAFCG_00978 2.1e-34
HCBLAFCG_00979 1.4e-53
HCBLAFCG_00980 6.7e-70
HCBLAFCG_00981 3.6e-29
HCBLAFCG_00982 3.2e-43
HCBLAFCG_00984 6.2e-14 S Helix-turn-helix of insertion element transposase
HCBLAFCG_00985 3.1e-89 L Resolvase, N terminal domain
HCBLAFCG_00986 9.3e-151 S TIGRFAM Phage
HCBLAFCG_00987 8.3e-124 S Phage portal protein, SPP1 Gp6-like
HCBLAFCG_00988 1.5e-29 S Domain of unknown function (DUF4355)
HCBLAFCG_00989 4e-95 S Phage capsid family
HCBLAFCG_00991 1.7e-19 S Phage gp6-like head-tail connector protein
HCBLAFCG_00993 0.0 S peptidoglycan catabolic process
HCBLAFCG_00994 5e-11
HCBLAFCG_00995 1.8e-13
HCBLAFCG_00996 4e-33 S Domain of unknown function (DUF4917)
HCBLAFCG_00997 2e-16 S Protein of unknown function (DUF1433)
HCBLAFCG_00998 1.7e-58 ywnC S Family of unknown function (DUF5362)
HCBLAFCG_00999 1e-142 mta K transcriptional
HCBLAFCG_01000 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCBLAFCG_01001 2.9e-70 ywnF S Family of unknown function (DUF5392)
HCBLAFCG_01002 7.2e-09 ywnC S Family of unknown function (DUF5362)
HCBLAFCG_01003 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HCBLAFCG_01004 2e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HCBLAFCG_01005 3.6e-32 L Restriction endonuclease BamHI
HCBLAFCG_01006 1.4e-18 K Helix-turn-helix XRE-family like proteins
HCBLAFCG_01007 3.9e-123 2.1.1.72 L DNA methylase
HCBLAFCG_01008 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HCBLAFCG_01009 1.6e-58 nrgB K Belongs to the P(II) protein family
HCBLAFCG_01010 4.3e-225 amt P Ammonium transporter
HCBLAFCG_01011 8.3e-76
HCBLAFCG_01012 6.8e-104 phzA Q Isochorismatase family
HCBLAFCG_01013 3.5e-239 ywoD EGP Major facilitator superfamily
HCBLAFCG_01014 4.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HCBLAFCG_01015 2.6e-229 ywoF P Right handed beta helix region
HCBLAFCG_01017 2.7e-211 ywoG EGP Major facilitator Superfamily
HCBLAFCG_01018 2.1e-70 ywoH K COG1846 Transcriptional regulators
HCBLAFCG_01019 3e-44 spoIIID K Stage III sporulation protein D
HCBLAFCG_01020 3.5e-180 mbl D Rod shape-determining protein
HCBLAFCG_01021 2.9e-124 flhO N flagellar basal body
HCBLAFCG_01022 1.7e-140 flhP N flagellar basal body
HCBLAFCG_01023 2.3e-198 S aspartate phosphatase
HCBLAFCG_01024 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCBLAFCG_01025 1.9e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCBLAFCG_01026 1.3e-146 ywpD T Histidine kinase
HCBLAFCG_01027 5.2e-50 srtA 3.4.22.70 M Sortase family
HCBLAFCG_01028 1.1e-66 ywpF S YwpF-like protein
HCBLAFCG_01029 3.8e-66 ywpG
HCBLAFCG_01030 3.7e-57 ssbB L Single-stranded DNA-binding protein
HCBLAFCG_01031 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HCBLAFCG_01032 1.1e-153 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HCBLAFCG_01033 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HCBLAFCG_01034 2.1e-307 ywqB S SWIM zinc finger
HCBLAFCG_01035 1.2e-17
HCBLAFCG_01036 3.8e-115 ywqC M biosynthesis protein
HCBLAFCG_01037 5.8e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HCBLAFCG_01038 8.7e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HCBLAFCG_01039 7e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCBLAFCG_01040 2.1e-151 ywqG S Domain of unknown function (DUF1963)
HCBLAFCG_01041 9.7e-23 S Domain of unknown function (DUF5082)
HCBLAFCG_01042 3.9e-38 ywqI S Family of unknown function (DUF5344)
HCBLAFCG_01043 5.7e-213 ywqJ S Pre-toxin TG
HCBLAFCG_01044 6.1e-43
HCBLAFCG_01045 5.2e-17
HCBLAFCG_01046 7.3e-82 ywqJ S Pre-toxin TG
HCBLAFCG_01047 3.9e-25
HCBLAFCG_01048 8.7e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HCBLAFCG_01049 1.9e-161 K Transcriptional regulator
HCBLAFCG_01050 1.1e-100 ywqN S NAD(P)H-dependent
HCBLAFCG_01052 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
HCBLAFCG_01053 1.6e-103 ywrB P Chromate transporter
HCBLAFCG_01054 8e-82 ywrC K Transcriptional regulator
HCBLAFCG_01055 5.5e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HCBLAFCG_01056 5e-54 S Domain of unknown function (DUF4181)
HCBLAFCG_01057 1.4e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HCBLAFCG_01058 3.7e-12
HCBLAFCG_01059 1.3e-209 cotH M Spore Coat
HCBLAFCG_01060 8.2e-131 cotB
HCBLAFCG_01061 7.5e-126 ywrJ
HCBLAFCG_01062 9.4e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HCBLAFCG_01063 1.1e-169 alsR K LysR substrate binding domain
HCBLAFCG_01064 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HCBLAFCG_01065 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HCBLAFCG_01066 1.3e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HCBLAFCG_01067 8e-48 ywsA S Protein of unknown function (DUF3892)
HCBLAFCG_01068 5.2e-90 batE T Sh3 type 3 domain protein
HCBLAFCG_01069 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HCBLAFCG_01070 1.2e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
HCBLAFCG_01071 5.6e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HCBLAFCG_01072 1.5e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCBLAFCG_01073 1.2e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCBLAFCG_01074 5.5e-178 rbsR K transcriptional
HCBLAFCG_01075 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HCBLAFCG_01076 8.6e-70 pgsC S biosynthesis protein
HCBLAFCG_01077 4.8e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HCBLAFCG_01078 3.6e-21 ywtC
HCBLAFCG_01079 1.4e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HCBLAFCG_01080 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBLAFCG_01081 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HCBLAFCG_01082 1.1e-63 yngL S Protein of unknown function (DUF1360)
HCBLAFCG_01083 7.7e-304 yngK T Glycosyl hydrolase-like 10
HCBLAFCG_01084 1.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HCBLAFCG_01085 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCBLAFCG_01086 8.1e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HCBLAFCG_01087 1.9e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HCBLAFCG_01088 1.7e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HCBLAFCG_01089 5.4e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HCBLAFCG_01090 2e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HCBLAFCG_01091 1.1e-231 nrnB S phosphohydrolase (DHH superfamily)
HCBLAFCG_01092 2.7e-103 yngC S membrane-associated protein
HCBLAFCG_01093 9.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HCBLAFCG_01094 1.6e-78 yngA S membrane
HCBLAFCG_01095 2.3e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HCBLAFCG_01096 1.8e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HCBLAFCG_01098 1.7e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HCBLAFCG_01099 5.3e-251 agcS E Sodium alanine symporter
HCBLAFCG_01100 1.3e-57 ynfC
HCBLAFCG_01101 2.3e-12
HCBLAFCG_01102 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCBLAFCG_01103 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCBLAFCG_01104 6.6e-69 yccU S CoA-binding protein
HCBLAFCG_01105 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCBLAFCG_01106 2.9e-47 yneR S Belongs to the HesB IscA family
HCBLAFCG_01107 2.2e-53 yneQ
HCBLAFCG_01108 1.2e-73 yneP S Thioesterase-like superfamily
HCBLAFCG_01109 6.5e-30 tlp S Belongs to the Tlp family
HCBLAFCG_01110 3.1e-08 sspN S Small acid-soluble spore protein N family
HCBLAFCG_01112 6.5e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HCBLAFCG_01113 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HCBLAFCG_01114 2.2e-14 sspO S Belongs to the SspO family
HCBLAFCG_01115 3.9e-19 sspP S Belongs to the SspP family
HCBLAFCG_01116 1.5e-62 hspX O Spore coat protein
HCBLAFCG_01117 3.6e-73 yneK S Protein of unknown function (DUF2621)
HCBLAFCG_01118 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HCBLAFCG_01119 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HCBLAFCG_01120 1.2e-126 ccdA O cytochrome c biogenesis protein
HCBLAFCG_01121 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HCBLAFCG_01122 1.8e-28 yneF S UPF0154 protein
HCBLAFCG_01123 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HCBLAFCG_01124 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCBLAFCG_01125 1.3e-32 ynzC S UPF0291 protein
HCBLAFCG_01126 9.2e-113 yneB L resolvase
HCBLAFCG_01127 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HCBLAFCG_01128 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCBLAFCG_01129 6.4e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HCBLAFCG_01130 1.7e-73 yndM S Protein of unknown function (DUF2512)
HCBLAFCG_01131 3.2e-133 yndL S Replication protein
HCBLAFCG_01133 2.2e-304 yndJ S YndJ-like protein
HCBLAFCG_01134 7.1e-115 yndH S Domain of unknown function (DUF4166)
HCBLAFCG_01135 2.9e-153 yndG S DoxX-like family
HCBLAFCG_01136 4.2e-220 gerLC S Spore germination protein
HCBLAFCG_01137 5e-196 gerAB U Spore germination
HCBLAFCG_01138 3.4e-283 gerAA EG Spore germination protein
HCBLAFCG_01141 1.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HCBLAFCG_01142 9e-71
HCBLAFCG_01143 3e-24 tatA U protein secretion
HCBLAFCG_01146 4.5e-121 S Domain of unknown function, YrpD
HCBLAFCG_01148 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HCBLAFCG_01149 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HCBLAFCG_01150 1.2e-84 gerD
HCBLAFCG_01151 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HCBLAFCG_01152 4.3e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCBLAFCG_01153 5.3e-64 ybaK S Protein of unknown function (DUF2521)
HCBLAFCG_01154 2.6e-143 ybaJ Q Methyltransferase domain
HCBLAFCG_01155 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HCBLAFCG_01156 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCBLAFCG_01157 4.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCBLAFCG_01158 3e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBLAFCG_01159 3.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBLAFCG_01160 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBLAFCG_01161 3.6e-58 rplQ J Ribosomal protein L17
HCBLAFCG_01162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBLAFCG_01163 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCBLAFCG_01164 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCBLAFCG_01165 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HCBLAFCG_01166 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCBLAFCG_01167 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HCBLAFCG_01168 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCBLAFCG_01169 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCBLAFCG_01170 1.8e-72 rplO J binds to the 23S rRNA
HCBLAFCG_01171 1.9e-23 rpmD J Ribosomal protein L30
HCBLAFCG_01172 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCBLAFCG_01173 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCBLAFCG_01174 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCBLAFCG_01175 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCBLAFCG_01176 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCBLAFCG_01177 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCBLAFCG_01178 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCBLAFCG_01179 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCBLAFCG_01180 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCBLAFCG_01181 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HCBLAFCG_01182 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCBLAFCG_01183 6.8e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCBLAFCG_01184 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCBLAFCG_01185 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCBLAFCG_01186 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCBLAFCG_01187 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCBLAFCG_01188 3e-105 rplD J Forms part of the polypeptide exit tunnel
HCBLAFCG_01189 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCBLAFCG_01190 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HCBLAFCG_01191 1.6e-185 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HCBLAFCG_01192 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCBLAFCG_01193 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCBLAFCG_01194 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCBLAFCG_01195 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCBLAFCG_01196 1.4e-32 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HCBLAFCG_01197 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBLAFCG_01198 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBLAFCG_01199 3.1e-107 rsmC 2.1.1.172 J Methyltransferase
HCBLAFCG_01200 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCBLAFCG_01201 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCBLAFCG_01202 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCBLAFCG_01203 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCBLAFCG_01204 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HCBLAFCG_01205 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCBLAFCG_01206 4.4e-115 sigH K Belongs to the sigma-70 factor family
HCBLAFCG_01207 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HCBLAFCG_01208 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCBLAFCG_01209 4e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCBLAFCG_01210 1.2e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCBLAFCG_01211 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HCBLAFCG_01212 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCBLAFCG_01213 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HCBLAFCG_01214 1.1e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HCBLAFCG_01215 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HCBLAFCG_01216 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HCBLAFCG_01217 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCBLAFCG_01218 0.0 clpC O Belongs to the ClpA ClpB family
HCBLAFCG_01219 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HCBLAFCG_01220 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HCBLAFCG_01221 2.9e-76 ctsR K Belongs to the CtsR family
HCBLAFCG_01222 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HCBLAFCG_01223 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCBLAFCG_01224 4.1e-30 yazB K transcriptional
HCBLAFCG_01225 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HCBLAFCG_01226 1e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCBLAFCG_01227 2.9e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HCBLAFCG_01228 1.9e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HCBLAFCG_01229 7.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HCBLAFCG_01230 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCBLAFCG_01231 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HCBLAFCG_01232 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HCBLAFCG_01233 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCBLAFCG_01234 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HCBLAFCG_01235 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCBLAFCG_01236 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HCBLAFCG_01237 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCBLAFCG_01238 1.3e-185 KLT serine threonine protein kinase
HCBLAFCG_01239 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HCBLAFCG_01240 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HCBLAFCG_01243 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HCBLAFCG_01244 8.9e-44 divIC D Septum formation initiator
HCBLAFCG_01245 2.5e-107 yabQ S spore cortex biosynthesis protein
HCBLAFCG_01246 1.5e-49 yabP S Sporulation protein YabP
HCBLAFCG_01247 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HCBLAFCG_01248 1.2e-242 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HCBLAFCG_01249 5.4e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCBLAFCG_01250 1.5e-92 spoVT K stage V sporulation protein
HCBLAFCG_01251 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCBLAFCG_01252 2.4e-39 yabK S Peptide ABC transporter permease
HCBLAFCG_01253 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCBLAFCG_01254 1.1e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HCBLAFCG_01255 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCBLAFCG_01256 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCBLAFCG_01257 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HCBLAFCG_01258 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HCBLAFCG_01259 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HCBLAFCG_01260 1.6e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCBLAFCG_01261 8.3e-27 sspF S DNA topological change
HCBLAFCG_01262 7.8e-39 veg S protein conserved in bacteria
HCBLAFCG_01263 1.6e-136 yabG S peptidase
HCBLAFCG_01264 4.5e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCBLAFCG_01265 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCBLAFCG_01266 2e-167 rpfB GH23 T protein conserved in bacteria
HCBLAFCG_01267 1.2e-143 tatD L hydrolase, TatD
HCBLAFCG_01268 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCBLAFCG_01269 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HCBLAFCG_01270 9.6e-150 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCBLAFCG_01271 1.5e-49 yazA L endonuclease containing a URI domain
HCBLAFCG_01272 6.1e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
HCBLAFCG_01273 4.8e-31 yabA L Involved in initiation control of chromosome replication
HCBLAFCG_01274 6.1e-146 yaaT S stage 0 sporulation protein
HCBLAFCG_01275 1.1e-181 holB 2.7.7.7 L DNA polymerase III
HCBLAFCG_01276 1.5e-71 yaaR S protein conserved in bacteria
HCBLAFCG_01277 2.2e-54 yaaQ S protein conserved in bacteria
HCBLAFCG_01278 1.8e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCBLAFCG_01279 1.1e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HCBLAFCG_01280 8.4e-202 yaaN P Belongs to the TelA family
HCBLAFCG_01281 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HCBLAFCG_01282 3.4e-31 csfB S Inhibitor of sigma-G Gin
HCBLAFCG_01283 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCBLAFCG_01284 9.5e-71 ywhA K Transcriptional regulator
HCBLAFCG_01285 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HCBLAFCG_01286 5.1e-119 ywhC S Peptidase family M50
HCBLAFCG_01287 5.2e-95 ywhD S YwhD family
HCBLAFCG_01288 3.6e-49
HCBLAFCG_01289 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCBLAFCG_01290 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HCBLAFCG_01291 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HCBLAFCG_01292 1e-84 ywhH S Aminoacyl-tRNA editing domain
HCBLAFCG_01294 5.8e-78 S aspartate phosphatase
HCBLAFCG_01295 7.8e-191 ywhK CO amine dehydrogenase activity
HCBLAFCG_01296 8.6e-246 ywhL CO amine dehydrogenase activity
HCBLAFCG_01298 2.9e-248 L Peptidase, M16
HCBLAFCG_01299 1e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
HCBLAFCG_01300 3e-232 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HCBLAFCG_01301 7.4e-132 cbiO V ABC transporter
HCBLAFCG_01303 1.9e-269 C Fe-S oxidoreductases
HCBLAFCG_01304 1e-07 S Bacteriocin subtilosin A
HCBLAFCG_01305 4.7e-73 ywiB S protein conserved in bacteria
HCBLAFCG_01306 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HCBLAFCG_01307 1.3e-213 narK P COG2223 Nitrate nitrite transporter
HCBLAFCG_01308 6.9e-130 fnr K helix_turn_helix, cAMP Regulatory protein
HCBLAFCG_01309 1.8e-138 ywiC S YwiC-like protein
HCBLAFCG_01310 3.5e-85 arfM T cyclic nucleotide binding
HCBLAFCG_01311 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCBLAFCG_01312 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
HCBLAFCG_01313 6.2e-94 narJ 1.7.5.1 C nitrate reductase
HCBLAFCG_01314 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
HCBLAFCG_01315 1.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCBLAFCG_01316 0.0 ywjA V ABC transporter
HCBLAFCG_01317 1.1e-95 ywjB H RibD C-terminal domain
HCBLAFCG_01318 5.6e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HCBLAFCG_01319 1.7e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HCBLAFCG_01320 0.0 fadF C COG0247 Fe-S oxidoreductase
HCBLAFCG_01321 2.8e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HCBLAFCG_01322 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCBLAFCG_01323 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCBLAFCG_01324 1.2e-112 ywnB S NAD(P)H-binding
HCBLAFCG_01325 1.7e-64 ywnA K Transcriptional regulator
HCBLAFCG_01326 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HCBLAFCG_01327 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HCBLAFCG_01328 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HCBLAFCG_01329 3.8e-11 csbD K CsbD-like
HCBLAFCG_01330 3e-84 ywmF S Peptidase M50
HCBLAFCG_01331 6.1e-104 S response regulator aspartate phosphatase
HCBLAFCG_01332 3.8e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HCBLAFCG_01333 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HCBLAFCG_01335 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HCBLAFCG_01336 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HCBLAFCG_01337 2.1e-175 spoIID D Stage II sporulation protein D
HCBLAFCG_01338 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCBLAFCG_01339 3.1e-133 ywmB S TATA-box binding
HCBLAFCG_01340 1.3e-32 ywzB S membrane
HCBLAFCG_01341 4.8e-87 ywmA
HCBLAFCG_01342 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HCBLAFCG_01343 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCBLAFCG_01344 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCBLAFCG_01345 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCBLAFCG_01346 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCBLAFCG_01347 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCBLAFCG_01348 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCBLAFCG_01349 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HCBLAFCG_01350 2.5e-62 atpI S ATP synthase
HCBLAFCG_01351 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCBLAFCG_01352 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCBLAFCG_01353 3.6e-94 ywlG S Belongs to the UPF0340 family
HCBLAFCG_01354 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HCBLAFCG_01355 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCBLAFCG_01356 1.7e-91 mntP P Probably functions as a manganese efflux pump
HCBLAFCG_01357 8.1e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCBLAFCG_01358 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HCBLAFCG_01359 6.1e-112 spoIIR S stage II sporulation protein R
HCBLAFCG_01360 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
HCBLAFCG_01362 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCBLAFCG_01363 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCBLAFCG_01364 2.6e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBLAFCG_01365 1.6e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HCBLAFCG_01366 8.6e-160 ywkB S Membrane transport protein
HCBLAFCG_01367 0.0 sfcA 1.1.1.38 C malic enzyme
HCBLAFCG_01368 7e-104 tdk 2.7.1.21 F thymidine kinase
HCBLAFCG_01369 1.1e-32 rpmE J Binds the 23S rRNA
HCBLAFCG_01370 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCBLAFCG_01371 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HCBLAFCG_01372 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCBLAFCG_01373 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCBLAFCG_01374 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HCBLAFCG_01375 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HCBLAFCG_01376 6e-91 ywjG S Domain of unknown function (DUF2529)
HCBLAFCG_01379 7.5e-94 M Glycosyltransferase like family
HCBLAFCG_01380 5.4e-119 H Methionine biosynthesis protein MetW
HCBLAFCG_01381 3.6e-194 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCBLAFCG_01382 9.3e-216 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
HCBLAFCG_01383 1.3e-96 ynaD J Acetyltransferase (GNAT) domain
HCBLAFCG_01385 2.8e-75 S CAAX protease self-immunity
HCBLAFCG_01386 1e-07 S Uncharacterised protein family (UPF0715)
HCBLAFCG_01387 5.5e-53 ynaF
HCBLAFCG_01390 7.9e-255 xynT G MFS/sugar transport protein
HCBLAFCG_01391 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HCBLAFCG_01392 2.3e-212 xylR GK ROK family
HCBLAFCG_01393 2e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HCBLAFCG_01394 4e-289 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HCBLAFCG_01395 5.4e-110 yokF 3.1.31.1 L RNA catabolic process
HCBLAFCG_01396 2.8e-252 iolT EGP Major facilitator Superfamily
HCBLAFCG_01397 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCBLAFCG_01399 6.5e-81 yncE S Protein of unknown function (DUF2691)
HCBLAFCG_01400 2.7e-76 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HCBLAFCG_01401 5.2e-15
HCBLAFCG_01404 3.3e-163 S Thymidylate synthase
HCBLAFCG_01405 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HCBLAFCG_01406 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HCBLAFCG_01407 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCBLAFCG_01408 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCBLAFCG_01409 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCBLAFCG_01410 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCBLAFCG_01411 1.4e-95 yaaI Q COG1335 Amidases related to nicotinamidase
HCBLAFCG_01412 1.8e-208 yaaH M Glycoside Hydrolase Family
HCBLAFCG_01413 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HCBLAFCG_01414 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HCBLAFCG_01415 1.3e-09
HCBLAFCG_01416 1.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCBLAFCG_01417 1.8e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HCBLAFCG_01418 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HCBLAFCG_01419 8.9e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HCBLAFCG_01420 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HCBLAFCG_01421 2.5e-180 yaaC S YaaC-like Protein
HCBLAFCG_01422 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBLAFCG_01423 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBLAFCG_01424 9.4e-250 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBLAFCG_01425 3.5e-70 Q Collagen triple helix repeat (20 copies)
HCBLAFCG_01426 8.3e-23
HCBLAFCG_01427 4.7e-22
HCBLAFCG_01428 3.2e-27 S PFAM FRG domain
HCBLAFCG_01429 7.1e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
HCBLAFCG_01431 1.2e-82 dnaB 3.6.4.12 L replicative DNA helicase
HCBLAFCG_01432 1.3e-38 L Arm DNA-binding domain
HCBLAFCG_01433 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
HCBLAFCG_01434 4.3e-68 glnR K transcriptional
HCBLAFCG_01435 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HCBLAFCG_01436 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCBLAFCG_01437 3.3e-68 spoVK O stage V sporulation protein K
HCBLAFCG_01438 1.2e-244 cisA2 L Recombinase
HCBLAFCG_01440 3.4e-90 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCBLAFCG_01441 8.4e-11 K Cro/C1-type HTH DNA-binding domain
HCBLAFCG_01452 6.5e-164 S Calcineurin-like phosphoesterase
HCBLAFCG_01453 2.5e-30 sspB S spore protein
HCBLAFCG_01456 7e-36
HCBLAFCG_01458 2.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCBLAFCG_01459 1.1e-161 S Thymidylate synthase
HCBLAFCG_01464 3.6e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HCBLAFCG_01465 2.2e-35 O Glutaredoxin
HCBLAFCG_01466 2.6e-86 L HNH endonuclease
HCBLAFCG_01467 1.1e-104 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBLAFCG_01468 5.6e-25 S HNH endonuclease
HCBLAFCG_01469 1.9e-172 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBLAFCG_01470 3.9e-75 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBLAFCG_01471 1.4e-114 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBLAFCG_01472 7.9e-67 S NrdI Flavodoxin like
HCBLAFCG_01479 8.7e-24 S hydrolase activity
HCBLAFCG_01485 2.1e-150 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HCBLAFCG_01486 1.8e-73 2.1.1.113, 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HCBLAFCG_01487 8.7e-90 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HCBLAFCG_01488 8e-85 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
HCBLAFCG_01493 3.7e-101 DR0488 S protein conserved in bacteria
HCBLAFCG_01494 0.0 S Bacterial DNA polymerase III alpha subunit
HCBLAFCG_01495 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HCBLAFCG_01496 1.1e-222 L DNA primase activity
HCBLAFCG_01497 1e-284 3.6.4.12 J DnaB-like helicase C terminal domain
HCBLAFCG_01498 1.2e-85
HCBLAFCG_01499 7.6e-180 L AAA domain
HCBLAFCG_01500 1.2e-155
HCBLAFCG_01504 0.0 M Parallel beta-helix repeats
HCBLAFCG_01505 6.8e-69 S Pfam:DUF867
HCBLAFCG_01506 5.1e-55 S Pfam:DUF867
HCBLAFCG_01508 2.1e-09 L transposase activity
HCBLAFCG_01510 4.5e-123 yoqW S Belongs to the SOS response-associated peptidase family
HCBLAFCG_01511 3.3e-136 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HCBLAFCG_01513 4.5e-63 S Phage regulatory protein Rha (Phage_pRha)
HCBLAFCG_01522 7.2e-10 S YopX protein
HCBLAFCG_01527 1.1e-33 K Transcriptional regulator
HCBLAFCG_01528 1.8e-176
HCBLAFCG_01529 6e-263 S DNA-sulfur modification-associated
HCBLAFCG_01530 1.7e-196 L Belongs to the 'phage' integrase family
HCBLAFCG_01535 5.6e-129
HCBLAFCG_01536 8.1e-33 V HNH endonuclease
HCBLAFCG_01539 2.4e-61
HCBLAFCG_01546 3.7e-08
HCBLAFCG_01551 9.4e-204
HCBLAFCG_01554 0.0 S RNA-directed RNA polymerase activity
HCBLAFCG_01555 6.5e-16 L GIY-YIG type nucleases (URI domain)
HCBLAFCG_01556 1.6e-90
HCBLAFCG_01557 1.9e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCBLAFCG_01559 1.7e-45 S hydrolase activity
HCBLAFCG_01560 5e-125
HCBLAFCG_01562 7e-175
HCBLAFCG_01563 0.0 gp17a S Terminase-like family
HCBLAFCG_01564 9.4e-278
HCBLAFCG_01565 1.8e-246
HCBLAFCG_01566 2.3e-93
HCBLAFCG_01567 1.3e-185
HCBLAFCG_01568 1.9e-80
HCBLAFCG_01569 1.3e-66
HCBLAFCG_01571 2e-120
HCBLAFCG_01572 7.6e-91
HCBLAFCG_01573 8.1e-131
HCBLAFCG_01574 1e-89
HCBLAFCG_01577 3.8e-52
HCBLAFCG_01578 6.3e-30
HCBLAFCG_01581 3.1e-57
HCBLAFCG_01582 8.9e-61
HCBLAFCG_01583 1.2e-191 xerH A Belongs to the 'phage' integrase family
HCBLAFCG_01585 1.3e-20
HCBLAFCG_01586 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HCBLAFCG_01587 3.5e-87 S Phage tail protein
HCBLAFCG_01588 2.5e-302 S Pfam Transposase IS66
HCBLAFCG_01589 9.5e-99
HCBLAFCG_01590 4.2e-56 S outer membrane
HCBLAFCG_01591 1.4e-163
HCBLAFCG_01592 1.6e-186 3.5.1.28 M Ami_2
HCBLAFCG_01593 4.4e-32 bhlA S BhlA holin family
HCBLAFCG_01594 5.5e-40 S SPP1 phage holin
HCBLAFCG_01595 3.4e-74 O protein disulfide oxidoreductase activity
HCBLAFCG_01596 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCBLAFCG_01597 1.2e-70 CO cell redox homeostasis
HCBLAFCG_01598 0.0 V Peptidase C39 family
HCBLAFCG_01601 1.9e-236 S impB/mucB/samB family C-terminal domain
HCBLAFCG_01602 4.6e-52 S YolD-like protein
HCBLAFCG_01603 4e-59 L nuclease activity
HCBLAFCG_01604 1.8e-91 yokK S SMI1 / KNR4 family
HCBLAFCG_01605 8.2e-76 S SMI1-KNR4 cell-wall
HCBLAFCG_01606 1.7e-172 yobL S Bacterial EndoU nuclease
HCBLAFCG_01607 7.6e-65 G SMI1-KNR4 cell-wall
HCBLAFCG_01608 1.9e-108 yokF 3.1.31.1 L RNA catabolic process
HCBLAFCG_01609 6.4e-80 yhbS S family acetyltransferase
HCBLAFCG_01611 2.4e-97 spoVK O stage V sporulation protein K
HCBLAFCG_01612 1.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCBLAFCG_01613 7.6e-109 ymaB
HCBLAFCG_01614 5.9e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBLAFCG_01615 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBLAFCG_01616 3e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HCBLAFCG_01617 4.5e-22 ymzA
HCBLAFCG_01618 1.6e-23
HCBLAFCG_01619 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HCBLAFCG_01620 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCBLAFCG_01621 2.1e-46 ymaF S YmaF family
HCBLAFCG_01623 4.9e-51 ebrA P Small Multidrug Resistance protein
HCBLAFCG_01624 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HCBLAFCG_01625 1e-78 ymaD O redox protein, regulator of disulfide bond formation
HCBLAFCG_01626 2.1e-126 ymaC S Replication protein
HCBLAFCG_01627 1.9e-07 K Transcriptional regulator
HCBLAFCG_01628 8.6e-251 aprX O Belongs to the peptidase S8 family
HCBLAFCG_01629 2.8e-162 ymaE S Metallo-beta-lactamase superfamily
HCBLAFCG_01630 4.4e-61 ymzB
HCBLAFCG_01631 6.3e-232 cypA C Cytochrome P450
HCBLAFCG_01632 0.0 pks13 HQ Beta-ketoacyl synthase
HCBLAFCG_01633 0.0 dhbF IQ polyketide synthase
HCBLAFCG_01634 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HCBLAFCG_01635 0.0 pfaA Q Polyketide synthase of type I
HCBLAFCG_01636 0.0 rhiB IQ polyketide synthase
HCBLAFCG_01637 4e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HCBLAFCG_01638 1.3e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
HCBLAFCG_01639 7.4e-244 pksG 2.3.3.10 I synthase
HCBLAFCG_01640 4.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCBLAFCG_01641 1.4e-37 acpK IQ Phosphopantetheine attachment site
HCBLAFCG_01642 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HCBLAFCG_01643 4.3e-183 pksD Q Acyl transferase domain
HCBLAFCG_01644 1.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HCBLAFCG_01645 6.1e-128 pksB 3.1.2.6 S Polyketide biosynthesis
HCBLAFCG_01646 4.2e-107 pksA K Transcriptional regulator
HCBLAFCG_01647 1.1e-95 ymcC S Membrane
HCBLAFCG_01648 1.3e-68 S Regulatory protein YrvL
HCBLAFCG_01649 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCBLAFCG_01650 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCBLAFCG_01651 2.2e-88 cotE S Spore coat protein
HCBLAFCG_01652 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HCBLAFCG_01653 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HCBLAFCG_01654 1.8e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HCBLAFCG_01655 3.6e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HCBLAFCG_01656 1.2e-36 spoVS S Stage V sporulation protein S
HCBLAFCG_01657 1.9e-152 ymdB S protein conserved in bacteria
HCBLAFCG_01658 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HCBLAFCG_01659 1.7e-213 pbpX V Beta-lactamase
HCBLAFCG_01660 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCBLAFCG_01661 4.3e-236 cinA 3.5.1.42 S Belongs to the CinA family
HCBLAFCG_01662 1.6e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCBLAFCG_01663 1.9e-124 ymfM S protein conserved in bacteria
HCBLAFCG_01664 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HCBLAFCG_01665 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HCBLAFCG_01666 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HCBLAFCG_01667 1.4e-242 ymfH S zinc protease
HCBLAFCG_01668 1.3e-232 ymfF S Peptidase M16
HCBLAFCG_01669 3.8e-205 ymfD EGP Major facilitator Superfamily
HCBLAFCG_01670 1.4e-133 ymfC K Transcriptional regulator
HCBLAFCG_01671 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HCBLAFCG_01672 4.4e-32 S YlzJ-like protein
HCBLAFCG_01673 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HCBLAFCG_01674 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCBLAFCG_01675 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCBLAFCG_01676 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HCBLAFCG_01677 1.2e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCBLAFCG_01678 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HCBLAFCG_01679 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HCBLAFCG_01680 2.6e-42 ymxH S YlmC YmxH family
HCBLAFCG_01681 4.4e-233 pepR S Belongs to the peptidase M16 family
HCBLAFCG_01682 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HCBLAFCG_01683 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HCBLAFCG_01684 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCBLAFCG_01685 2.3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HCBLAFCG_01686 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCBLAFCG_01687 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCBLAFCG_01688 3e-44 ylxP S protein conserved in bacteria
HCBLAFCG_01689 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCBLAFCG_01690 3.1e-47 ylxQ J ribosomal protein
HCBLAFCG_01691 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HCBLAFCG_01692 1.1e-203 nusA K Participates in both transcription termination and antitermination
HCBLAFCG_01693 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HCBLAFCG_01694 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCBLAFCG_01695 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCBLAFCG_01696 7.7e-233 rasP M zinc metalloprotease
HCBLAFCG_01697 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HCBLAFCG_01698 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HCBLAFCG_01699 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCBLAFCG_01700 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCBLAFCG_01701 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HCBLAFCG_01702 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCBLAFCG_01703 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HCBLAFCG_01704 3.1e-76 ylxL
HCBLAFCG_01705 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCBLAFCG_01706 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HCBLAFCG_01707 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HCBLAFCG_01708 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HCBLAFCG_01709 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HCBLAFCG_01710 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HCBLAFCG_01711 4.1e-156 flhG D Belongs to the ParA family
HCBLAFCG_01712 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
HCBLAFCG_01713 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HCBLAFCG_01714 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HCBLAFCG_01715 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HCBLAFCG_01716 2.2e-36 fliQ N Role in flagellar biosynthesis
HCBLAFCG_01717 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HCBLAFCG_01718 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
HCBLAFCG_01719 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HCBLAFCG_01720 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HCBLAFCG_01721 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HCBLAFCG_01722 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HCBLAFCG_01723 8.2e-140 flgG N Flagellar basal body rod
HCBLAFCG_01724 2.3e-72 flgD N Flagellar basal body rod modification protein
HCBLAFCG_01725 3.6e-218 fliK N Flagellar hook-length control protein
HCBLAFCG_01726 3.8e-36 ylxF S MgtE intracellular N domain
HCBLAFCG_01727 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HCBLAFCG_01728 1.2e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HCBLAFCG_01729 3.7e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HCBLAFCG_01730 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HCBLAFCG_01731 2e-254 fliF N The M ring may be actively involved in energy transduction
HCBLAFCG_01732 1.9e-31 fliE N Flagellar hook-basal body
HCBLAFCG_01733 2e-74 flgC N Belongs to the flagella basal body rod proteins family
HCBLAFCG_01734 8.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HCBLAFCG_01735 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HCBLAFCG_01736 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCBLAFCG_01737 7.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCBLAFCG_01738 2.5e-169 xerC L tyrosine recombinase XerC
HCBLAFCG_01739 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HCBLAFCG_01740 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCBLAFCG_01741 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HCBLAFCG_01742 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HCBLAFCG_01743 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HCBLAFCG_01744 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HCBLAFCG_01745 1.4e-288 ylqG
HCBLAFCG_01746 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCBLAFCG_01747 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCBLAFCG_01748 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCBLAFCG_01749 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HCBLAFCG_01750 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCBLAFCG_01751 6.3e-61 ylqD S YlqD protein
HCBLAFCG_01752 4.5e-36 ylqC S Belongs to the UPF0109 family
HCBLAFCG_01753 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HCBLAFCG_01754 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCBLAFCG_01755 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCBLAFCG_01756 2.9e-87
HCBLAFCG_01757 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCBLAFCG_01758 0.0 smc D Required for chromosome condensation and partitioning
HCBLAFCG_01759 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCBLAFCG_01760 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCBLAFCG_01761 5.1e-128 IQ reductase
HCBLAFCG_01762 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HCBLAFCG_01763 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCBLAFCG_01764 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HCBLAFCG_01765 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCBLAFCG_01766 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HCBLAFCG_01767 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HCBLAFCG_01768 1.1e-300 yloV S kinase related to dihydroxyacetone kinase
HCBLAFCG_01769 5.5e-59 asp S protein conserved in bacteria
HCBLAFCG_01770 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HCBLAFCG_01771 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HCBLAFCG_01772 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HCBLAFCG_01773 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCBLAFCG_01774 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HCBLAFCG_01775 1e-139 stp 3.1.3.16 T phosphatase
HCBLAFCG_01776 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HCBLAFCG_01777 2.3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCBLAFCG_01778 2e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCBLAFCG_01779 1.9e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCBLAFCG_01780 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCBLAFCG_01781 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCBLAFCG_01782 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCBLAFCG_01783 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HCBLAFCG_01784 1.5e-40 ylzA S Belongs to the UPF0296 family
HCBLAFCG_01785 1.2e-155 yloC S stress-induced protein
HCBLAFCG_01786 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HCBLAFCG_01787 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HCBLAFCG_01788 1.4e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HCBLAFCG_01789 3.5e-143 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HCBLAFCG_01790 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HCBLAFCG_01791 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HCBLAFCG_01792 4.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HCBLAFCG_01793 1.2e-178 cysP P phosphate transporter
HCBLAFCG_01794 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HCBLAFCG_01796 2.8e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCBLAFCG_01797 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCBLAFCG_01798 1.7e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCBLAFCG_01799 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HCBLAFCG_01800 0.0 carB 6.3.5.5 F Belongs to the CarB family
HCBLAFCG_01801 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCBLAFCG_01802 1.9e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCBLAFCG_01803 2.6e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HCBLAFCG_01804 4.5e-231 pyrP F Xanthine uracil
HCBLAFCG_01805 3.6e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCBLAFCG_01806 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCBLAFCG_01807 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCBLAFCG_01808 1.3e-63 dksA T COG1734 DnaK suppressor protein
HCBLAFCG_01809 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCBLAFCG_01810 2.6e-67 divIVA D Cell division initiation protein
HCBLAFCG_01811 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HCBLAFCG_01812 2.8e-39 yggT S membrane
HCBLAFCG_01813 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCBLAFCG_01814 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HCBLAFCG_01815 7e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HCBLAFCG_01816 2.4e-37 ylmC S sporulation protein
HCBLAFCG_01817 7.7e-249 argE 3.5.1.16 E Acetylornithine deacetylase
HCBLAFCG_01818 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HCBLAFCG_01819 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCBLAFCG_01820 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCBLAFCG_01821 6.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HCBLAFCG_01823 0.0 bpr O COG1404 Subtilisin-like serine proteases
HCBLAFCG_01824 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCBLAFCG_01825 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCBLAFCG_01826 8.9e-57 sbp S small basic protein
HCBLAFCG_01827 8.2e-117 ylxX S protein conserved in bacteria
HCBLAFCG_01828 2.4e-103 ylxW S protein conserved in bacteria
HCBLAFCG_01829 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCBLAFCG_01830 5.3e-167 murB 1.3.1.98 M cell wall formation
HCBLAFCG_01831 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCBLAFCG_01832 5.7e-186 spoVE D Belongs to the SEDS family
HCBLAFCG_01833 2.2e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCBLAFCG_01834 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCBLAFCG_01835 8.9e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCBLAFCG_01836 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HCBLAFCG_01837 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HCBLAFCG_01838 3.7e-44 ftsL D Essential cell division protein
HCBLAFCG_01839 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCBLAFCG_01840 2.9e-78 mraZ K Belongs to the MraZ family
HCBLAFCG_01841 6e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HCBLAFCG_01842 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCBLAFCG_01843 1.5e-88 ylbP K n-acetyltransferase
HCBLAFCG_01844 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HCBLAFCG_01845 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HCBLAFCG_01846 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HCBLAFCG_01848 3e-229 ylbM S Belongs to the UPF0348 family
HCBLAFCG_01849 6.8e-187 ylbL T Belongs to the peptidase S16 family
HCBLAFCG_01850 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HCBLAFCG_01851 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
HCBLAFCG_01852 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCBLAFCG_01853 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
HCBLAFCG_01854 4.9e-38 ylbG S UPF0298 protein
HCBLAFCG_01855 1.8e-75 ylbF S Belongs to the UPF0342 family
HCBLAFCG_01856 1.5e-36 ylbE S YlbE-like protein
HCBLAFCG_01857 3.4e-62 ylbD S Putative coat protein
HCBLAFCG_01858 1.6e-199 ylbC S protein with SCP PR1 domains
HCBLAFCG_01859 2.6e-74 ylbB T COG0517 FOG CBS domain
HCBLAFCG_01860 3.5e-61 ylbA S YugN-like family
HCBLAFCG_01861 2.6e-166 ctaG S cytochrome c oxidase
HCBLAFCG_01862 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HCBLAFCG_01863 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HCBLAFCG_01864 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HCBLAFCG_01865 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HCBLAFCG_01866 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HCBLAFCG_01867 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HCBLAFCG_01868 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HCBLAFCG_01869 1.9e-212 ftsW D Belongs to the SEDS family
HCBLAFCG_01870 8.7e-44 ylaN S Belongs to the UPF0358 family
HCBLAFCG_01871 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HCBLAFCG_01872 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HCBLAFCG_01873 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HCBLAFCG_01874 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCBLAFCG_01875 2.5e-32 ylaI S protein conserved in bacteria
HCBLAFCG_01876 4.2e-47 ylaH S YlaH-like protein
HCBLAFCG_01877 0.0 typA T GTP-binding protein TypA
HCBLAFCG_01878 8.2e-22 S Family of unknown function (DUF5325)
HCBLAFCG_01879 4.1e-38 ylaE
HCBLAFCG_01880 7.1e-12 sigC S Putative zinc-finger
HCBLAFCG_01881 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HCBLAFCG_01882 2.7e-42 ylaB
HCBLAFCG_01883 0.0 ylaA
HCBLAFCG_01884 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HCBLAFCG_01885 8.7e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HCBLAFCG_01886 2.2e-76 ykzC S Acetyltransferase (GNAT) family
HCBLAFCG_01887 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HCBLAFCG_01888 7.1e-26 ykzI
HCBLAFCG_01889 2.1e-117 yktB S Belongs to the UPF0637 family
HCBLAFCG_01890 1.6e-42 yktA S Belongs to the UPF0223 family
HCBLAFCG_01891 3.5e-277 speA 4.1.1.19 E Arginine
HCBLAFCG_01892 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HCBLAFCG_01893 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCBLAFCG_01894 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCBLAFCG_01895 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCBLAFCG_01896 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCBLAFCG_01897 2e-115 recN L Putative cell-wall binding lipoprotein
HCBLAFCG_01899 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCBLAFCG_01900 1.4e-147 ykrA S hydrolases of the HAD superfamily
HCBLAFCG_01901 8.2e-31 ykzG S Belongs to the UPF0356 family
HCBLAFCG_01902 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCBLAFCG_01903 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HCBLAFCG_01904 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HCBLAFCG_01905 1.2e-51 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HCBLAFCG_01906 7.2e-73 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HCBLAFCG_01907 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HCBLAFCG_01908 1.5e-43 abrB K of stationary sporulation gene expression
HCBLAFCG_01909 7.7e-183 mreB D Rod-share determining protein MreBH
HCBLAFCG_01910 1.1e-12 S Uncharacterized protein YkpC
HCBLAFCG_01911 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HCBLAFCG_01912 2.2e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCBLAFCG_01913 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HCBLAFCG_01914 8.1e-39 ykoA
HCBLAFCG_01915 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HCBLAFCG_01916 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HCBLAFCG_01917 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HCBLAFCG_01918 3.1e-136 fruR K Transcriptional regulator
HCBLAFCG_01919 4.3e-209 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HCBLAFCG_01920 2.5e-124 macB V ABC transporter, ATP-binding protein
HCBLAFCG_01921 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCBLAFCG_01922 7.2e-116 yknW S Yip1 domain
HCBLAFCG_01923 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCBLAFCG_01924 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCBLAFCG_01925 1.8e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HCBLAFCG_01926 9.4e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HCBLAFCG_01927 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HCBLAFCG_01928 2.2e-243 moeA 2.10.1.1 H molybdopterin
HCBLAFCG_01929 4.5e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HCBLAFCG_01930 2.4e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HCBLAFCG_01931 1.6e-145 yknT
HCBLAFCG_01932 5.8e-95 rok K Repressor of ComK
HCBLAFCG_01933 6.3e-81 ykuV CO thiol-disulfide
HCBLAFCG_01934 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HCBLAFCG_01935 8.8e-142 ykuT M Mechanosensitive ion channel
HCBLAFCG_01936 9e-37 ykuS S Belongs to the UPF0180 family
HCBLAFCG_01937 2.7e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCBLAFCG_01938 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCBLAFCG_01939 8.7e-78 fld C Flavodoxin
HCBLAFCG_01940 2.6e-174 ykuO
HCBLAFCG_01941 1.6e-85 fld C Flavodoxin domain
HCBLAFCG_01942 3.5e-168 ccpC K Transcriptional regulator
HCBLAFCG_01943 1.6e-76 ykuL S CBS domain
HCBLAFCG_01944 3.9e-27 ykzF S Antirepressor AbbA
HCBLAFCG_01945 4.4e-94 ykuK S Ribonuclease H-like
HCBLAFCG_01946 3.9e-37 ykuJ S protein conserved in bacteria
HCBLAFCG_01947 5.2e-234 ykuI T Diguanylate phosphodiesterase
HCBLAFCG_01948 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_01949 9.4e-166 ykuE S Metallophosphoesterase
HCBLAFCG_01950 1.8e-87 ykuD S protein conserved in bacteria
HCBLAFCG_01951 9.9e-236 ykuC EGP Major facilitator Superfamily
HCBLAFCG_01952 1.7e-84 ykyB S YkyB-like protein
HCBLAFCG_01953 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HCBLAFCG_01954 2.2e-15
HCBLAFCG_01955 2e-222 patA 2.6.1.1 E Aminotransferase
HCBLAFCG_01956 0.0 pilS 2.7.13.3 T Histidine kinase
HCBLAFCG_01957 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HCBLAFCG_01958 3e-123 ykwD J protein with SCP PR1 domains
HCBLAFCG_01959 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HCBLAFCG_01960 1.9e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HCBLAFCG_01961 6.7e-260 mcpC NT chemotaxis protein
HCBLAFCG_01962 6.6e-125 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBLAFCG_01963 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
HCBLAFCG_01964 7.2e-39 splA S Transcriptional regulator
HCBLAFCG_01965 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCBLAFCG_01966 2.1e-39 ptsH G phosphocarrier protein HPr
HCBLAFCG_01967 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCBLAFCG_01968 1.9e-126 glcT K antiterminator
HCBLAFCG_01970 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
HCBLAFCG_01971 6.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HCBLAFCG_01972 2.3e-09
HCBLAFCG_01973 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HCBLAFCG_01974 4.9e-90 stoA CO thiol-disulfide
HCBLAFCG_01975 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCBLAFCG_01976 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
HCBLAFCG_01977 2.8e-28
HCBLAFCG_01978 6e-25 ykvS S protein conserved in bacteria
HCBLAFCG_01979 1.1e-44 ykvR S Protein of unknown function (DUF3219)
HCBLAFCG_01980 6.9e-162 G Glycosyl hydrolases family 18
HCBLAFCG_01981 3.5e-35 3.5.1.104 M LysM domain
HCBLAFCG_01982 5.6e-233 ykvP 3.5.1.28 M Glycosyl transferases group 1
HCBLAFCG_01983 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
HCBLAFCG_01984 2.9e-60 ykvN K Transcriptional regulator
HCBLAFCG_01985 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HCBLAFCG_01986 8.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HCBLAFCG_01987 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HCBLAFCG_01988 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HCBLAFCG_01989 4.8e-180 ykvI S membrane
HCBLAFCG_01990 0.0 clpE O Belongs to the ClpA ClpB family
HCBLAFCG_01991 1e-137 motA N flagellar motor
HCBLAFCG_01992 2.5e-125 motB N Flagellar motor protein
HCBLAFCG_01993 1.3e-75 ykvE K transcriptional
HCBLAFCG_01994 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HCBLAFCG_01995 1.4e-64 eag
HCBLAFCG_01996 6.4e-09 S Spo0E like sporulation regulatory protein
HCBLAFCG_01997 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HCBLAFCG_01998 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HCBLAFCG_01999 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HCBLAFCG_02000 1.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HCBLAFCG_02001 5e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HCBLAFCG_02002 2.4e-228 mtnE 2.6.1.83 E Aminotransferase
HCBLAFCG_02003 6.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HCBLAFCG_02004 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HCBLAFCG_02005 3.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HCBLAFCG_02007 5.9e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCBLAFCG_02008 0.0 kinE 2.7.13.3 T Histidine kinase
HCBLAFCG_02009 9.4e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HCBLAFCG_02010 4.1e-18 ykzE
HCBLAFCG_02011 1.2e-10 ydfR S Protein of unknown function (DUF421)
HCBLAFCG_02012 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HCBLAFCG_02013 3.5e-155 htpX O Belongs to the peptidase M48B family
HCBLAFCG_02014 3.3e-124 ykrK S Domain of unknown function (DUF1836)
HCBLAFCG_02015 1.9e-26 sspD S small acid-soluble spore protein
HCBLAFCG_02016 5.2e-111 rsgI S Anti-sigma factor N-terminus
HCBLAFCG_02017 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCBLAFCG_02018 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HCBLAFCG_02019 5.4e-110 ykoX S membrane-associated protein
HCBLAFCG_02020 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HCBLAFCG_02021 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HCBLAFCG_02022 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HCBLAFCG_02023 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCBLAFCG_02024 0.0 ykoS
HCBLAFCG_02025 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HCBLAFCG_02026 1.1e-98 ykoP G polysaccharide deacetylase
HCBLAFCG_02027 3.4e-213 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HCBLAFCG_02028 1.3e-81 mhqR K transcriptional
HCBLAFCG_02029 3.4e-25 ykoL
HCBLAFCG_02030 1.3e-17
HCBLAFCG_02031 1.4e-53 tnrA K transcriptional
HCBLAFCG_02032 2.2e-222 mgtE P Acts as a magnesium transporter
HCBLAFCG_02035 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
HCBLAFCG_02036 2e-110 ykoI S Peptidase propeptide and YPEB domain
HCBLAFCG_02037 2.7e-239 ykoH 2.7.13.3 T Histidine kinase
HCBLAFCG_02038 4.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_02039 5.1e-110 ykoF S YKOF-related Family
HCBLAFCG_02040 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HCBLAFCG_02041 3.4e-305 P ABC transporter, ATP-binding protein
HCBLAFCG_02042 4.5e-135 ykoC P Cobalt transport protein
HCBLAFCG_02043 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HCBLAFCG_02044 1.5e-175 isp O Belongs to the peptidase S8 family
HCBLAFCG_02045 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HCBLAFCG_02046 6.2e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HCBLAFCG_02047 8.4e-72 ohrB O Organic hydroperoxide resistance protein
HCBLAFCG_02048 4.4e-74 ohrR K COG1846 Transcriptional regulators
HCBLAFCG_02049 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HCBLAFCG_02050 1.2e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCBLAFCG_02051 2.2e-199 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCBLAFCG_02052 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HCBLAFCG_02053 7e-50 ykkD P Multidrug resistance protein
HCBLAFCG_02054 3.5e-55 ykkC P Multidrug resistance protein
HCBLAFCG_02055 5.1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HCBLAFCG_02056 1.5e-97 ykkA S Protein of unknown function (DUF664)
HCBLAFCG_02057 2.7e-129 ykjA S Protein of unknown function (DUF421)
HCBLAFCG_02058 5.5e-09
HCBLAFCG_02059 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HCBLAFCG_02060 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HCBLAFCG_02061 1.2e-160 ykgA E Amidinotransferase
HCBLAFCG_02062 3.1e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
HCBLAFCG_02063 7.2e-186 ykfD E Belongs to the ABC transporter superfamily
HCBLAFCG_02064 3.1e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HCBLAFCG_02065 4.4e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HCBLAFCG_02066 4.5e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HCBLAFCG_02068 0.0 dppE E ABC transporter substrate-binding protein
HCBLAFCG_02069 1.3e-187 dppD P Belongs to the ABC transporter superfamily
HCBLAFCG_02070 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCBLAFCG_02071 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCBLAFCG_02072 2.5e-152 dppA E D-aminopeptidase
HCBLAFCG_02073 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HCBLAFCG_02074 7.5e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCBLAFCG_02076 1.9e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCBLAFCG_02077 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCBLAFCG_02078 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HCBLAFCG_02079 6.8e-240 steT E amino acid
HCBLAFCG_02080 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HCBLAFCG_02081 5.8e-175 pit P phosphate transporter
HCBLAFCG_02082 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HCBLAFCG_02083 6.7e-23 spoIISB S Stage II sporulation protein SB
HCBLAFCG_02084 4.2e-161 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCBLAFCG_02085 9.3e-40 xhlB S SPP1 phage holin
HCBLAFCG_02086 1.1e-38 xhlA S Haemolysin XhlA
HCBLAFCG_02087 3.4e-152 xepA
HCBLAFCG_02088 5.5e-22 xkdX
HCBLAFCG_02089 2.7e-44 xkdW S XkdW protein
HCBLAFCG_02090 5.5e-179
HCBLAFCG_02091 6.7e-41
HCBLAFCG_02092 4.2e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HCBLAFCG_02093 3.3e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HCBLAFCG_02094 1.3e-67 xkdS S Protein of unknown function (DUF2634)
HCBLAFCG_02095 4.7e-39 xkdR S Protein of unknown function (DUF2577)
HCBLAFCG_02096 4e-181 yqbQ 3.2.1.96 G NLP P60 protein
HCBLAFCG_02097 2.7e-118 xkdP S Lysin motif
HCBLAFCG_02098 1.4e-261 xkdO L Transglycosylase SLT domain
HCBLAFCG_02099 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
HCBLAFCG_02100 1e-75 xkdM S Phage tail tube protein
HCBLAFCG_02101 9.3e-256 xkdK S Phage tail sheath C-terminal domain
HCBLAFCG_02102 1.2e-76 xkdJ
HCBLAFCG_02103 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HCBLAFCG_02104 6.2e-63 yqbH S Domain of unknown function (DUF3599)
HCBLAFCG_02105 4.3e-62 yqbG S Protein of unknown function (DUF3199)
HCBLAFCG_02106 5.8e-169 xkdG S Phage capsid family
HCBLAFCG_02107 1.3e-132 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HCBLAFCG_02108 5.1e-284 yqbA S portal protein
HCBLAFCG_02109 1.4e-253 xtmB S phage terminase, large subunit
HCBLAFCG_02110 5e-137 xtmA L phage terminase small subunit
HCBLAFCG_02111 1.3e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HCBLAFCG_02112 2.3e-09 yqaO S Phage-like element PBSX protein XtrA
HCBLAFCG_02115 4.1e-118 xkdC L Bacterial dnaA protein
HCBLAFCG_02116 4.3e-155 xkdB K sequence-specific DNA binding
HCBLAFCG_02118 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HCBLAFCG_02119 1.6e-111 xkdA E IrrE N-terminal-like domain
HCBLAFCG_02120 4.4e-160 ydbD P Catalase
HCBLAFCG_02121 1.3e-108 yjqB S Pfam:DUF867
HCBLAFCG_02122 6.1e-61 yjqA S Bacterial PH domain
HCBLAFCG_02123 1.6e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HCBLAFCG_02124 4e-25 S YCII-related domain
HCBLAFCG_02126 1e-212 S response regulator aspartate phosphatase
HCBLAFCG_02127 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HCBLAFCG_02128 2.3e-78 yjoA S DinB family
HCBLAFCG_02129 7.4e-130 MA20_18170 S membrane transporter protein
HCBLAFCG_02130 8.7e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HCBLAFCG_02131 1.1e-278 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HCBLAFCG_02132 1.5e-183 exuR K transcriptional
HCBLAFCG_02133 6.3e-227 exuT G Sugar (and other) transporter
HCBLAFCG_02134 6.8e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_02135 8.9e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HCBLAFCG_02136 4.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HCBLAFCG_02137 1.1e-186 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HCBLAFCG_02138 9.2e-248 yjmB G symporter YjmB
HCBLAFCG_02139 8.7e-278 uxaC 5.3.1.12 G glucuronate isomerase
HCBLAFCG_02140 5.9e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HCBLAFCG_02141 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HCBLAFCG_02142 7.5e-91 yjlB S Cupin domain
HCBLAFCG_02143 1.3e-174 yjlA EG Putative multidrug resistance efflux transporter
HCBLAFCG_02144 1.7e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HCBLAFCG_02145 1.6e-121 ybbM S transport system, permease component
HCBLAFCG_02146 1.9e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HCBLAFCG_02147 8.2e-30
HCBLAFCG_02148 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HCBLAFCG_02149 1.5e-222 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HCBLAFCG_02151 1.5e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HCBLAFCG_02152 8.7e-07 S Domain of unknown function (DUF4352)
HCBLAFCG_02153 4.3e-95 yjgD S Protein of unknown function (DUF1641)
HCBLAFCG_02154 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HCBLAFCG_02155 3.4e-103 yjgB S Domain of unknown function (DUF4309)
HCBLAFCG_02156 6.9e-59 yjfC O Predicted Zn-dependent protease (DUF2268)
HCBLAFCG_02157 2.9e-91 yjfC O Predicted Zn-dependent protease (DUF2268)
HCBLAFCG_02158 3.6e-21 yjfB S Putative motility protein
HCBLAFCG_02159 5.5e-83 S Protein of unknown function (DUF2690)
HCBLAFCG_02160 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HCBLAFCG_02162 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HCBLAFCG_02163 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HCBLAFCG_02164 3.4e-21 S Domain of unknown function (DUF4177)
HCBLAFCG_02165 1.2e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCBLAFCG_02167 2.2e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HCBLAFCG_02168 4.1e-50 yjdF S Protein of unknown function (DUF2992)
HCBLAFCG_02169 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HCBLAFCG_02170 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HCBLAFCG_02171 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HCBLAFCG_02173 1.7e-139 IQ Enoyl-(Acyl carrier protein) reductase
HCBLAFCG_02174 3.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
HCBLAFCG_02175 3.4e-85 S response regulator aspartate phosphatase
HCBLAFCG_02176 2.2e-81 S response regulator aspartate phosphatase
HCBLAFCG_02178 8.2e-119 S Abortive infection C-terminus
HCBLAFCG_02179 2.8e-98 V HNH nucleases
HCBLAFCG_02181 1.1e-41
HCBLAFCG_02182 2.8e-182 I Pfam Lipase (class 3)
HCBLAFCG_02183 2.2e-91 yuaB
HCBLAFCG_02184 3.6e-94 yuaC K Belongs to the GbsR family
HCBLAFCG_02185 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HCBLAFCG_02186 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
HCBLAFCG_02187 1.1e-106 yuaD
HCBLAFCG_02188 3.9e-84 yuaE S DinB superfamily
HCBLAFCG_02189 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HCBLAFCG_02190 5.3e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HCBLAFCG_02191 5.8e-94 M1-753 M FR47-like protein
HCBLAFCG_02192 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HCBLAFCG_02193 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBLAFCG_02194 1.5e-134 L Integrase core domain
HCBLAFCG_02195 6e-44 tnpIS3 L Transposase
HCBLAFCG_02200 1.3e-09
HCBLAFCG_02207 2e-08
HCBLAFCG_02210 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HCBLAFCG_02211 7.9e-236 ktrB P Potassium
HCBLAFCG_02212 1e-38 yiaA S yiaA/B two helix domain
HCBLAFCG_02213 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCBLAFCG_02214 2.4e-273 yubD P Major Facilitator Superfamily
HCBLAFCG_02215 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HCBLAFCG_02217 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCBLAFCG_02218 1.3e-194 yubA S transporter activity
HCBLAFCG_02219 3.3e-183 ygjR S Oxidoreductase
HCBLAFCG_02220 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HCBLAFCG_02221 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HCBLAFCG_02222 5.1e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HCBLAFCG_02223 6.6e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HCBLAFCG_02224 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HCBLAFCG_02225 7.3e-238 mcpA NT chemotaxis protein
HCBLAFCG_02226 4.7e-293 mcpA NT chemotaxis protein
HCBLAFCG_02227 2.4e-220 mcpA NT chemotaxis protein
HCBLAFCG_02228 3.2e-225 mcpA NT chemotaxis protein
HCBLAFCG_02229 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HCBLAFCG_02230 2.3e-35
HCBLAFCG_02231 1.8e-71 yugU S Uncharacterised protein family UPF0047
HCBLAFCG_02232 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HCBLAFCG_02233 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HCBLAFCG_02234 1.4e-116 yugP S Zn-dependent protease
HCBLAFCG_02235 2.3e-38
HCBLAFCG_02236 5.4e-53 mstX S Membrane-integrating protein Mistic
HCBLAFCG_02237 8.2e-182 yugO P COG1226 Kef-type K transport systems
HCBLAFCG_02238 1.3e-72 yugN S YugN-like family
HCBLAFCG_02240 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HCBLAFCG_02241 1.1e-228 yugK C Dehydrogenase
HCBLAFCG_02242 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HCBLAFCG_02243 1.1e-34 yuzA S Domain of unknown function (DUF378)
HCBLAFCG_02244 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HCBLAFCG_02245 5.3e-198 yugH 2.6.1.1 E Aminotransferase
HCBLAFCG_02246 1.6e-85 alaR K Transcriptional regulator
HCBLAFCG_02247 4.9e-156 yugF I Hydrolase
HCBLAFCG_02248 1.6e-39 yugE S Domain of unknown function (DUF1871)
HCBLAFCG_02249 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HCBLAFCG_02250 4.6e-233 T PhoQ Sensor
HCBLAFCG_02251 3.1e-68 kapB G Kinase associated protein B
HCBLAFCG_02252 1.9e-115 kapD L the KinA pathway to sporulation
HCBLAFCG_02254 3.8e-185 yuxJ EGP Major facilitator Superfamily
HCBLAFCG_02255 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HCBLAFCG_02256 1.8e-74 yuxK S protein conserved in bacteria
HCBLAFCG_02257 6.3e-78 yufK S Family of unknown function (DUF5366)
HCBLAFCG_02258 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HCBLAFCG_02259 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HCBLAFCG_02260 2.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HCBLAFCG_02261 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HCBLAFCG_02262 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HCBLAFCG_02263 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HCBLAFCG_02264 1.3e-233 maeN C COG3493 Na citrate symporter
HCBLAFCG_02265 3.2e-14
HCBLAFCG_02266 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HCBLAFCG_02267 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCBLAFCG_02268 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCBLAFCG_02269 6.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCBLAFCG_02270 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCBLAFCG_02271 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCBLAFCG_02272 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HCBLAFCG_02273 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HCBLAFCG_02274 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCBLAFCG_02275 0.0 comP 2.7.13.3 T Histidine kinase
HCBLAFCG_02277 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
HCBLAFCG_02280 3.2e-22 yuzC
HCBLAFCG_02281 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HCBLAFCG_02282 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCBLAFCG_02283 9.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
HCBLAFCG_02284 7.9e-67 yueI S Protein of unknown function (DUF1694)
HCBLAFCG_02285 7.4e-39 yueH S YueH-like protein
HCBLAFCG_02286 2.1e-32 yueG S Spore germination protein gerPA/gerPF
HCBLAFCG_02287 2.1e-189 yueF S transporter activity
HCBLAFCG_02288 2.8e-69 S Protein of unknown function (DUF2283)
HCBLAFCG_02289 1.4e-23 S Protein of unknown function (DUF2642)
HCBLAFCG_02290 4.8e-96 yueE S phosphohydrolase
HCBLAFCG_02291 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_02292 3.3e-64 yueC S Family of unknown function (DUF5383)
HCBLAFCG_02293 0.0 esaA S type VII secretion protein EsaA
HCBLAFCG_02294 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HCBLAFCG_02295 5.7e-210 essB S WXG100 protein secretion system (Wss), protein YukC
HCBLAFCG_02296 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HCBLAFCG_02297 2.8e-45 esxA S Belongs to the WXG100 family
HCBLAFCG_02298 4.7e-227 yukF QT Transcriptional regulator
HCBLAFCG_02299 5.2e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HCBLAFCG_02300 1e-130 yukJ S Uncharacterized conserved protein (DUF2278)
HCBLAFCG_02301 5e-36 mbtH S MbtH-like protein
HCBLAFCG_02302 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBLAFCG_02303 2e-177 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HCBLAFCG_02304 1.6e-310 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HCBLAFCG_02305 4.7e-224 entC 5.4.4.2 HQ Isochorismate synthase
HCBLAFCG_02306 3.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_02307 3.9e-167 besA S Putative esterase
HCBLAFCG_02308 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HCBLAFCG_02309 1.7e-92 bioY S Biotin biosynthesis protein
HCBLAFCG_02310 3.9e-211 yuiF S antiporter
HCBLAFCG_02311 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HCBLAFCG_02312 1.2e-77 yuiD S protein conserved in bacteria
HCBLAFCG_02313 2.6e-115 yuiC S protein conserved in bacteria
HCBLAFCG_02314 7.1e-26 yuiB S Putative membrane protein
HCBLAFCG_02315 4.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
HCBLAFCG_02316 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HCBLAFCG_02318 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCBLAFCG_02319 1.6e-114 paiB K Putative FMN-binding domain
HCBLAFCG_02320 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBLAFCG_02321 3.7e-63 erpA S Belongs to the HesB IscA family
HCBLAFCG_02322 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCBLAFCG_02323 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HCBLAFCG_02324 3.2e-39 yuzB S Belongs to the UPF0349 family
HCBLAFCG_02325 4.5e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HCBLAFCG_02326 3.5e-57 yuzD S protein conserved in bacteria
HCBLAFCG_02327 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HCBLAFCG_02328 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HCBLAFCG_02329 4.3e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCBLAFCG_02330 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HCBLAFCG_02331 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
HCBLAFCG_02332 2.9e-198 yutH S Spore coat protein
HCBLAFCG_02333 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HCBLAFCG_02334 4.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCBLAFCG_02335 2.5e-74 yutE S Protein of unknown function DUF86
HCBLAFCG_02336 9.7e-48 yutD S protein conserved in bacteria
HCBLAFCG_02337 2.7e-109 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCBLAFCG_02338 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HCBLAFCG_02339 4.5e-196 lytH M Peptidase, M23
HCBLAFCG_02340 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
HCBLAFCG_02341 4.1e-47 yunC S Domain of unknown function (DUF1805)
HCBLAFCG_02342 6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HCBLAFCG_02343 2e-141 yunE S membrane transporter protein
HCBLAFCG_02344 4.3e-171 yunF S Protein of unknown function DUF72
HCBLAFCG_02345 8.2e-60 yunG
HCBLAFCG_02346 1.6e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HCBLAFCG_02347 3.2e-300 pucR QT COG2508 Regulator of polyketide synthase expression
HCBLAFCG_02348 7.9e-236 pbuX F Permease family
HCBLAFCG_02349 1.3e-224 pbuX F xanthine
HCBLAFCG_02350 1.1e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HCBLAFCG_02351 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HCBLAFCG_02352 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HCBLAFCG_02353 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HCBLAFCG_02354 3.7e-151 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HCBLAFCG_02355 3.1e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HCBLAFCG_02356 3.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HCBLAFCG_02358 3.2e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HCBLAFCG_02359 4.4e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HCBLAFCG_02360 2.4e-169 bsn L Ribonuclease
HCBLAFCG_02361 1e-204 msmX P Belongs to the ABC transporter superfamily
HCBLAFCG_02362 3.3e-135 yurK K UTRA
HCBLAFCG_02363 5.7e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HCBLAFCG_02364 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
HCBLAFCG_02365 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
HCBLAFCG_02366 8.5e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HCBLAFCG_02367 3.3e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HCBLAFCG_02368 1.3e-63 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HCBLAFCG_02369 1.2e-205 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HCBLAFCG_02371 1e-41
HCBLAFCG_02372 1e-63 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBLAFCG_02373 1.1e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCBLAFCG_02374 3.5e-271 sufB O FeS cluster assembly
HCBLAFCG_02375 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HCBLAFCG_02376 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCBLAFCG_02377 1.4e-245 sufD O assembly protein SufD
HCBLAFCG_02378 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HCBLAFCG_02379 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HCBLAFCG_02380 9.4e-147 metQ P Belongs to the NlpA lipoprotein family
HCBLAFCG_02381 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HCBLAFCG_02382 1.8e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCBLAFCG_02383 3.2e-56 yusD S SCP-2 sterol transfer family
HCBLAFCG_02384 5.6e-55 traF CO Thioredoxin
HCBLAFCG_02385 4.8e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HCBLAFCG_02386 1.1e-39 yusG S Protein of unknown function (DUF2553)
HCBLAFCG_02387 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HCBLAFCG_02388 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HCBLAFCG_02389 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HCBLAFCG_02390 5.5e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HCBLAFCG_02391 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HCBLAFCG_02392 8.1e-09 S YuzL-like protein
HCBLAFCG_02393 7.1e-164 fadM E Proline dehydrogenase
HCBLAFCG_02394 5.1e-40
HCBLAFCG_02395 5.4e-53 yusN M Coat F domain
HCBLAFCG_02396 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
HCBLAFCG_02397 4.7e-291 yusP P Major facilitator superfamily
HCBLAFCG_02398 2.7e-64 yusQ S Tautomerase enzyme
HCBLAFCG_02399 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_02400 2.2e-157 yusT K LysR substrate binding domain
HCBLAFCG_02401 3.8e-47 yusU S Protein of unknown function (DUF2573)
HCBLAFCG_02402 1e-153 yusV 3.6.3.34 HP ABC transporter
HCBLAFCG_02403 1.9e-66 S YusW-like protein
HCBLAFCG_02404 2.1e-300 pepF2 E COG1164 Oligoendopeptidase F
HCBLAFCG_02405 2.9e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_02406 1.2e-79 dps P Ferritin-like domain
HCBLAFCG_02407 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCBLAFCG_02408 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_02409 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HCBLAFCG_02410 4.3e-158 yuxN K Transcriptional regulator
HCBLAFCG_02411 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCBLAFCG_02412 2.3e-24 S Protein of unknown function (DUF3970)
HCBLAFCG_02413 1.4e-246 gerAA EG Spore germination protein
HCBLAFCG_02414 4.5e-197 gerAB E Spore germination protein
HCBLAFCG_02415 1.9e-187 gerAC S Spore germination B3/ GerAC like, C-terminal
HCBLAFCG_02416 8.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCBLAFCG_02417 3.5e-186 vraS 2.7.13.3 T Histidine kinase
HCBLAFCG_02418 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HCBLAFCG_02419 2.3e-127 liaG S Putative adhesin
HCBLAFCG_02420 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HCBLAFCG_02421 7.3e-62 liaI S membrane
HCBLAFCG_02422 1.4e-226 yvqJ EGP Major facilitator Superfamily
HCBLAFCG_02423 1.8e-99 yvqK 2.5.1.17 S Adenosyltransferase
HCBLAFCG_02424 1e-243 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HCBLAFCG_02425 2.2e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_02426 1.5e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HCBLAFCG_02427 3.4e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_02428 2.6e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HCBLAFCG_02429 0.0 T PhoQ Sensor
HCBLAFCG_02430 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_02431 7.2e-23
HCBLAFCG_02432 4.8e-70 yvrI K RNA polymerase
HCBLAFCG_02433 2.4e-19 S YvrJ protein family
HCBLAFCG_02434 1.8e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
HCBLAFCG_02435 8.4e-64 yvrL S Regulatory protein YrvL
HCBLAFCG_02436 8.9e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HCBLAFCG_02437 6e-123 macB V ABC transporter, ATP-binding protein
HCBLAFCG_02438 2e-174 M Efflux transporter rnd family, mfp subunit
HCBLAFCG_02439 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HCBLAFCG_02440 1.5e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_02441 8.7e-182 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_02442 9e-178 fhuD P ABC transporter
HCBLAFCG_02444 4.9e-236 yvsH E Arginine ornithine antiporter
HCBLAFCG_02445 6.5e-16 S Small spore protein J (Spore_SspJ)
HCBLAFCG_02446 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HCBLAFCG_02447 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HCBLAFCG_02448 8.3e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HCBLAFCG_02449 2.4e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HCBLAFCG_02450 1.8e-119 modB P COG4149 ABC-type molybdate transport system, permease component
HCBLAFCG_02451 5.9e-157 yvgN S reductase
HCBLAFCG_02452 4.6e-85 yvgO
HCBLAFCG_02453 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HCBLAFCG_02454 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HCBLAFCG_02455 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HCBLAFCG_02456 0.0 helD 3.6.4.12 L DNA helicase
HCBLAFCG_02458 1.6e-106 yvgT S membrane
HCBLAFCG_02459 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HCBLAFCG_02460 1.6e-104 bdbD O Thioredoxin
HCBLAFCG_02461 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HCBLAFCG_02462 0.0 copA 3.6.3.54 P P-type ATPase
HCBLAFCG_02463 1.5e-29 copZ P Copper resistance protein CopZ
HCBLAFCG_02464 2.2e-48 csoR S transcriptional
HCBLAFCG_02465 8.1e-196 yvaA 1.1.1.371 S Oxidoreductase
HCBLAFCG_02466 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCBLAFCG_02467 0.0 yvaC S Fusaric acid resistance protein-like
HCBLAFCG_02468 1.3e-72 yvaD S Family of unknown function (DUF5360)
HCBLAFCG_02469 2.4e-54 yvaE P Small Multidrug Resistance protein
HCBLAFCG_02470 2.7e-97 K Bacterial regulatory proteins, tetR family
HCBLAFCG_02471 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_02473 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HCBLAFCG_02474 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCBLAFCG_02475 5.6e-143 est 3.1.1.1 S Carboxylesterase
HCBLAFCG_02476 2.4e-23 secG U Preprotein translocase subunit SecG
HCBLAFCG_02477 2.6e-151 yvaM S Serine aminopeptidase, S33
HCBLAFCG_02478 7.5e-36 yvzC K Transcriptional
HCBLAFCG_02479 4e-69 K transcriptional
HCBLAFCG_02480 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
HCBLAFCG_02481 1.4e-53 yodB K transcriptional
HCBLAFCG_02482 3.8e-219 NT chemotaxis protein
HCBLAFCG_02483 1.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HCBLAFCG_02484 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCBLAFCG_02485 1.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HCBLAFCG_02486 3.1e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HCBLAFCG_02487 3.3e-60 yvbF K Belongs to the GbsR family
HCBLAFCG_02488 9.5e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HCBLAFCG_02489 1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCBLAFCG_02490 3.9e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HCBLAFCG_02491 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HCBLAFCG_02492 1.3e-96 yvbF K Belongs to the GbsR family
HCBLAFCG_02493 6.4e-103 yvbG U UPF0056 membrane protein
HCBLAFCG_02494 1.9e-112 yvbH S YvbH-like oligomerisation region
HCBLAFCG_02495 2.3e-122 exoY M Membrane
HCBLAFCG_02496 0.0 tcaA S response to antibiotic
HCBLAFCG_02497 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
HCBLAFCG_02498 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCBLAFCG_02499 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HCBLAFCG_02500 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCBLAFCG_02501 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HCBLAFCG_02502 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCBLAFCG_02503 2.6e-183 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HCBLAFCG_02504 1.6e-252 araE EGP Major facilitator Superfamily
HCBLAFCG_02505 5.5e-203 araR K transcriptional
HCBLAFCG_02506 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCBLAFCG_02507 8.7e-159 yvbU K Transcriptional regulator
HCBLAFCG_02508 1.2e-155 yvbV EG EamA-like transporter family
HCBLAFCG_02509 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HCBLAFCG_02510 3.6e-196 yvbX S Glycosyl hydrolase
HCBLAFCG_02511 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HCBLAFCG_02512 6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HCBLAFCG_02513 2.2e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HCBLAFCG_02514 3.8e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCBLAFCG_02515 1.5e-195 desK 2.7.13.3 T Histidine kinase
HCBLAFCG_02516 1.4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
HCBLAFCG_02517 4.4e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HCBLAFCG_02519 7.5e-157 rsbQ S Alpha/beta hydrolase family
HCBLAFCG_02520 2.2e-197 rsbU 3.1.3.3 T response regulator
HCBLAFCG_02521 6.6e-248 galA 3.2.1.89 G arabinogalactan
HCBLAFCG_02522 0.0 lacA 3.2.1.23 G beta-galactosidase
HCBLAFCG_02523 3.6e-149 ganQ P transport
HCBLAFCG_02524 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HCBLAFCG_02525 1e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
HCBLAFCG_02526 2e-183 lacR K Transcriptional regulator
HCBLAFCG_02527 2.3e-112 yvfI K COG2186 Transcriptional regulators
HCBLAFCG_02528 3.3e-308 yvfH C L-lactate permease
HCBLAFCG_02529 6.7e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HCBLAFCG_02530 1e-31 yvfG S YvfG protein
HCBLAFCG_02531 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
HCBLAFCG_02532 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HCBLAFCG_02533 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HCBLAFCG_02534 1.2e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HCBLAFCG_02535 8.3e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCBLAFCG_02536 2.7e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HCBLAFCG_02537 1.2e-202 epsI GM pyruvyl transferase
HCBLAFCG_02538 2e-194 epsH GT2 S Glycosyltransferase like family 2
HCBLAFCG_02539 1.8e-206 epsG S EpsG family
HCBLAFCG_02540 6.4e-218 epsF GT4 M Glycosyl transferases group 1
HCBLAFCG_02541 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCBLAFCG_02542 3.8e-223 epsD GT4 M Glycosyl transferase 4-like
HCBLAFCG_02543 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HCBLAFCG_02544 2.3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HCBLAFCG_02545 4e-122 ywqC M biosynthesis protein
HCBLAFCG_02546 6.3e-76 slr K transcriptional
HCBLAFCG_02547 2.7e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HCBLAFCG_02549 5.1e-92 padC Q Phenolic acid decarboxylase
HCBLAFCG_02550 7.6e-74 MA20_18690 S Protein of unknown function (DUF3237)
HCBLAFCG_02551 4.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HCBLAFCG_02552 2.8e-257 pbpE V Beta-lactamase
HCBLAFCG_02553 1e-273 sacB 2.4.1.10 GH68 M levansucrase activity
HCBLAFCG_02554 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HCBLAFCG_02555 1.8e-295 yveA E amino acid
HCBLAFCG_02556 7.4e-106 yvdT K Transcriptional regulator
HCBLAFCG_02557 4.3e-50 ykkC P Small Multidrug Resistance protein
HCBLAFCG_02558 2.7e-49 sugE P Small Multidrug Resistance protein
HCBLAFCG_02559 9.1e-92 yvdQ S Protein of unknown function (DUF3231)
HCBLAFCG_02561 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCBLAFCG_02562 5.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HCBLAFCG_02563 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HCBLAFCG_02564 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HCBLAFCG_02565 6.5e-154 malA S Protein of unknown function (DUF1189)
HCBLAFCG_02566 3.9e-148 malD P transport
HCBLAFCG_02567 1.4e-242 malC P COG1175 ABC-type sugar transport systems, permease components
HCBLAFCG_02568 2.8e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HCBLAFCG_02569 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HCBLAFCG_02570 8.8e-173 yvdE K Transcriptional regulator
HCBLAFCG_02571 7.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HCBLAFCG_02572 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HCBLAFCG_02573 1.4e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HCBLAFCG_02574 1.3e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HCBLAFCG_02575 1.8e-181 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBLAFCG_02576 0.0 yxdM V ABC transporter (permease)
HCBLAFCG_02577 1.6e-140 yvcR V ABC transporter, ATP-binding protein
HCBLAFCG_02578 1.7e-193 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HCBLAFCG_02579 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_02580 9.7e-32
HCBLAFCG_02581 4.4e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HCBLAFCG_02582 1.6e-36 crh G Phosphocarrier protein Chr
HCBLAFCG_02583 1.4e-170 whiA K May be required for sporulation
HCBLAFCG_02584 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HCBLAFCG_02585 5.7e-166 rapZ S Displays ATPase and GTPase activities
HCBLAFCG_02586 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HCBLAFCG_02587 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCBLAFCG_02588 2.8e-98 usp CBM50 M protein conserved in bacteria
HCBLAFCG_02589 8.4e-276 S COG0457 FOG TPR repeat
HCBLAFCG_02590 0.0 msbA2 3.6.3.44 V ABC transporter
HCBLAFCG_02592 1.8e-254
HCBLAFCG_02593 4.8e-78
HCBLAFCG_02594 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HCBLAFCG_02595 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCBLAFCG_02596 9.9e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HCBLAFCG_02597 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCBLAFCG_02598 5.1e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HCBLAFCG_02599 4.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCBLAFCG_02600 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HCBLAFCG_02601 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HCBLAFCG_02602 4.5e-140 yvpB NU protein conserved in bacteria
HCBLAFCG_02603 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HCBLAFCG_02604 9.6e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HCBLAFCG_02605 1.1e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HCBLAFCG_02606 1.6e-163 yvoD P COG0370 Fe2 transport system protein B
HCBLAFCG_02607 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCBLAFCG_02608 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCBLAFCG_02609 1.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCBLAFCG_02610 9.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCBLAFCG_02611 3.6e-134 yvoA K transcriptional
HCBLAFCG_02612 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HCBLAFCG_02613 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
HCBLAFCG_02614 5.3e-231 cypX 1.14.15.13 C Cytochrome P450
HCBLAFCG_02615 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HCBLAFCG_02616 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
HCBLAFCG_02617 3.3e-201 yvmA EGP Major facilitator Superfamily
HCBLAFCG_02618 1.2e-50 yvlD S Membrane
HCBLAFCG_02619 2.6e-26 pspB KT PspC domain
HCBLAFCG_02620 7e-166 yvlB S Putative adhesin
HCBLAFCG_02621 8e-49 yvlA
HCBLAFCG_02622 5.7e-33 yvkN
HCBLAFCG_02623 8.7e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HCBLAFCG_02624 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCBLAFCG_02625 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCBLAFCG_02626 1.2e-30 csbA S protein conserved in bacteria
HCBLAFCG_02627 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HCBLAFCG_02628 1e-99 yvkB K Transcriptional regulator
HCBLAFCG_02629 2.8e-225 yvkA EGP Major facilitator Superfamily
HCBLAFCG_02630 1.2e-219 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCBLAFCG_02631 2e-55 swrA S Swarming motility protein
HCBLAFCG_02632 1.5e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HCBLAFCG_02633 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HCBLAFCG_02634 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HCBLAFCG_02635 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HCBLAFCG_02636 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HCBLAFCG_02637 7.9e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCBLAFCG_02638 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCBLAFCG_02639 1.1e-101 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCBLAFCG_02640 4.6e-51
HCBLAFCG_02641 1.9e-08 fliT S bacterial-type flagellum organization
HCBLAFCG_02642 4.2e-68 fliS N flagellar protein FliS
HCBLAFCG_02643 2e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HCBLAFCG_02644 1.2e-55 flaG N flagellar protein FlaG
HCBLAFCG_02645 7.1e-110 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HCBLAFCG_02646 2.8e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HCBLAFCG_02647 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HCBLAFCG_02648 1.4e-48 yviE
HCBLAFCG_02649 7.8e-155 flgL N Belongs to the bacterial flagellin family
HCBLAFCG_02650 5.9e-264 flgK N flagellar hook-associated protein
HCBLAFCG_02651 2.4e-78 flgN NOU FlgN protein
HCBLAFCG_02652 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
HCBLAFCG_02653 7e-74 yvyF S flagellar protein
HCBLAFCG_02654 2.7e-129 comFC S Phosphoribosyl transferase domain
HCBLAFCG_02655 5.7e-46 comFB S Late competence development protein ComFB
HCBLAFCG_02656 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HCBLAFCG_02657 7.3e-155 degV S protein conserved in bacteria
HCBLAFCG_02658 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCBLAFCG_02659 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HCBLAFCG_02660 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HCBLAFCG_02661 6e-163 yvhJ K Transcriptional regulator
HCBLAFCG_02662 5.8e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HCBLAFCG_02663 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HCBLAFCG_02664 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HCBLAFCG_02665 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
HCBLAFCG_02666 1.1e-262 tuaE M Teichuronic acid biosynthesis protein
HCBLAFCG_02667 9e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCBLAFCG_02668 9.3e-217 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HCBLAFCG_02669 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCBLAFCG_02670 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HCBLAFCG_02671 2.8e-93 M Glycosyltransferase like family 2
HCBLAFCG_02672 9.1e-209 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCBLAFCG_02673 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HCBLAFCG_02674 1e-11
HCBLAFCG_02675 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HCBLAFCG_02676 6.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCBLAFCG_02677 2.1e-88 M Glycosyltransferase like family 2
HCBLAFCG_02678 1.6e-99 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HCBLAFCG_02679 7.5e-24 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HCBLAFCG_02680 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HCBLAFCG_02681 2.9e-269 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HCBLAFCG_02682 1e-132 tagG GM Transport permease protein
HCBLAFCG_02683 9.9e-89
HCBLAFCG_02684 2.7e-55
HCBLAFCG_02685 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCBLAFCG_02686 1e-89 ggaA M Glycosyltransferase like family 2
HCBLAFCG_02687 5.1e-146 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HCBLAFCG_02688 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HCBLAFCG_02689 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HCBLAFCG_02690 2.3e-94 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HCBLAFCG_02691 1e-104 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HCBLAFCG_02692 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HCBLAFCG_02693 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCBLAFCG_02694 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCBLAFCG_02695 3e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCBLAFCG_02696 2.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HCBLAFCG_02697 3.5e-266 gerBA EG Spore germination protein
HCBLAFCG_02698 8.3e-199 gerBB E Spore germination protein
HCBLAFCG_02699 9.9e-216 gerAC S Spore germination protein
HCBLAFCG_02700 1.2e-247 ywtG EGP Major facilitator Superfamily
HCBLAFCG_02701 3.2e-170 ywtF K Transcriptional regulator
HCBLAFCG_02702 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HCBLAFCG_02709 7.8e-08
HCBLAFCG_02717 2.6e-242 mmr U Major Facilitator Superfamily
HCBLAFCG_02718 2.8e-79 yffB K Transcriptional regulator
HCBLAFCG_02719 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HCBLAFCG_02720 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HCBLAFCG_02721 3.1e-36 ywzC S Belongs to the UPF0741 family
HCBLAFCG_02722 3e-110 rsfA_1
HCBLAFCG_02723 1.2e-158 ywfM EG EamA-like transporter family
HCBLAFCG_02724 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HCBLAFCG_02725 3.4e-158 cysL K Transcriptional regulator
HCBLAFCG_02726 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HCBLAFCG_02727 1.1e-146 ywfI C May function as heme-dependent peroxidase
HCBLAFCG_02728 7e-136 IQ Enoyl-(Acyl carrier protein) reductase
HCBLAFCG_02729 2.8e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
HCBLAFCG_02730 7.3e-209 bacE EGP Major facilitator Superfamily
HCBLAFCG_02731 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HCBLAFCG_02732 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_02733 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HCBLAFCG_02734 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HCBLAFCG_02735 3e-205 ywfA EGP Major facilitator Superfamily
HCBLAFCG_02736 1.4e-248 lysP E amino acid
HCBLAFCG_02737 0.0 rocB E arginine degradation protein
HCBLAFCG_02738 3.5e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HCBLAFCG_02739 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCBLAFCG_02740 5.8e-77
HCBLAFCG_02741 1.3e-86 spsL 5.1.3.13 M Spore Coat
HCBLAFCG_02742 5.8e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HCBLAFCG_02743 3.9e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HCBLAFCG_02744 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HCBLAFCG_02745 2e-186 spsG M Spore Coat
HCBLAFCG_02746 1.2e-129 spsF M Spore Coat
HCBLAFCG_02747 7.1e-214 spsE 2.5.1.56 M acid synthase
HCBLAFCG_02748 2.4e-161 spsD 2.3.1.210 K Spore Coat
HCBLAFCG_02749 4.3e-222 spsC E Belongs to the DegT DnrJ EryC1 family
HCBLAFCG_02750 3.1e-267 spsB M Capsule polysaccharide biosynthesis protein
HCBLAFCG_02751 2.4e-144 spsA M Spore Coat
HCBLAFCG_02752 1.4e-74 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HCBLAFCG_02753 7.4e-59 ywdK S small membrane protein
HCBLAFCG_02754 3.7e-238 ywdJ F Xanthine uracil
HCBLAFCG_02755 2.9e-48 ywdI S Family of unknown function (DUF5327)
HCBLAFCG_02756 2e-258 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HCBLAFCG_02757 3.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCBLAFCG_02758 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HCBLAFCG_02759 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCBLAFCG_02760 2e-28 ywdA
HCBLAFCG_02761 1.6e-290 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HCBLAFCG_02762 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCBLAFCG_02763 2.6e-138 focA P Formate/nitrite transporter
HCBLAFCG_02764 7e-150 sacT K transcriptional antiterminator
HCBLAFCG_02766 0.0 vpr O Belongs to the peptidase S8 family
HCBLAFCG_02767 3.6e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCBLAFCG_02768 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HCBLAFCG_02769 2.9e-202 rodA D Belongs to the SEDS family
HCBLAFCG_02770 5.2e-204 S Acetyltransferase
HCBLAFCG_02771 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HCBLAFCG_02772 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HCBLAFCG_02773 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HCBLAFCG_02774 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HCBLAFCG_02775 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HCBLAFCG_02776 1e-35 ywzA S membrane
HCBLAFCG_02777 1e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HCBLAFCG_02778 2.9e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCBLAFCG_02779 8.1e-59 gtcA S GtrA-like protein
HCBLAFCG_02780 1.1e-121 ywcC K transcriptional regulator
HCBLAFCG_02782 1.7e-48 ywcB S Protein of unknown function, DUF485
HCBLAFCG_02783 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCBLAFCG_02784 8.1e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HCBLAFCG_02785 8.4e-224 ywbN P Dyp-type peroxidase family protein
HCBLAFCG_02786 1.2e-163 ycdO P periplasmic lipoprotein involved in iron transport
HCBLAFCG_02787 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
HCBLAFCG_02788 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCBLAFCG_02789 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCBLAFCG_02790 4.3e-153 ywbI K Transcriptional regulator
HCBLAFCG_02791 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HCBLAFCG_02792 2.3e-111 ywbG M effector of murein hydrolase
HCBLAFCG_02793 1.1e-207 ywbF EGP Major facilitator Superfamily
HCBLAFCG_02794 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HCBLAFCG_02795 1.3e-221 ywbD 2.1.1.191 J Methyltransferase
HCBLAFCG_02796 4.4e-67 ywbC 4.4.1.5 E glyoxalase
HCBLAFCG_02797 2e-123 ywbB S Protein of unknown function (DUF2711)
HCBLAFCG_02798 1.6e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBLAFCG_02799 4.3e-275 epr 3.4.21.62 O Belongs to the peptidase S8 family
HCBLAFCG_02800 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCBLAFCG_02801 1.2e-152 sacY K transcriptional antiterminator
HCBLAFCG_02802 4.5e-168 gspA M General stress
HCBLAFCG_02803 3.7e-123 ywaF S Integral membrane protein
HCBLAFCG_02804 2.3e-87 ywaE K Transcriptional regulator
HCBLAFCG_02805 7e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCBLAFCG_02806 8.8e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HCBLAFCG_02807 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HCBLAFCG_02808 3.5e-166 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HCBLAFCG_02809 2.2e-290 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBLAFCG_02810 1e-231 dltB M membrane protein involved in D-alanine export
HCBLAFCG_02811 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBLAFCG_02812 2.5e-230 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCBLAFCG_02813 2.5e-15 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_02814 1.1e-92 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_02815 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HCBLAFCG_02816 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HCBLAFCG_02817 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HCBLAFCG_02818 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBLAFCG_02819 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HCBLAFCG_02820 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HCBLAFCG_02821 1.1e-19 yxzF
HCBLAFCG_02822 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HCBLAFCG_02823 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HCBLAFCG_02824 1.1e-212 yxlH EGP Major facilitator Superfamily
HCBLAFCG_02825 1.2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HCBLAFCG_02826 7e-164 yxlF V ABC transporter, ATP-binding protein
HCBLAFCG_02827 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HCBLAFCG_02828 1.4e-30
HCBLAFCG_02829 3.9e-48 yxlC S Family of unknown function (DUF5345)
HCBLAFCG_02830 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HCBLAFCG_02831 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HCBLAFCG_02832 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCBLAFCG_02833 0.0 cydD V ATP-binding protein
HCBLAFCG_02834 1.7e-310 cydD V ATP-binding
HCBLAFCG_02835 6.5e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HCBLAFCG_02836 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
HCBLAFCG_02837 1.5e-229 cimH C COG3493 Na citrate symporter
HCBLAFCG_02838 1.8e-309 3.4.24.84 O Peptidase family M48
HCBLAFCG_02840 4.7e-154 yxkH G Polysaccharide deacetylase
HCBLAFCG_02841 3.8e-204 msmK P Belongs to the ABC transporter superfamily
HCBLAFCG_02842 1.6e-163 lrp QT PucR C-terminal helix-turn-helix domain
HCBLAFCG_02843 3.6e-274 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCBLAFCG_02844 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCBLAFCG_02845 2.8e-74 yxkC S Domain of unknown function (DUF4352)
HCBLAFCG_02846 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HCBLAFCG_02847 2e-77 S Protein of unknown function (DUF1453)
HCBLAFCG_02848 2.6e-177 yxjM T Signal transduction histidine kinase
HCBLAFCG_02849 1.3e-111 K helix_turn_helix, Lux Regulon
HCBLAFCG_02850 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HCBLAFCG_02853 3.2e-86 yxjI S LURP-one-related
HCBLAFCG_02854 3.3e-219 yxjG 2.1.1.14 E Methionine synthase
HCBLAFCG_02855 1.8e-217 yxjG 2.1.1.14 E Methionine synthase
HCBLAFCG_02856 4.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HCBLAFCG_02857 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HCBLAFCG_02858 9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HCBLAFCG_02859 1.6e-250 yxjC EG COG2610 H gluconate symporter and related permeases
HCBLAFCG_02860 7.1e-158 rlmA 2.1.1.187 Q Methyltransferase domain
HCBLAFCG_02861 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HCBLAFCG_02862 7.2e-105 T Domain of unknown function (DUF4163)
HCBLAFCG_02863 3e-47 yxiS
HCBLAFCG_02864 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HCBLAFCG_02865 6.6e-224 citH C Citrate transporter
HCBLAFCG_02866 7.3e-143 exoK GH16 M licheninase activity
HCBLAFCG_02867 8.3e-151 licT K transcriptional antiterminator
HCBLAFCG_02868 4.7e-112
HCBLAFCG_02869 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
HCBLAFCG_02870 4.3e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HCBLAFCG_02871 1.7e-210 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HCBLAFCG_02874 8.6e-42 yxiJ S YxiJ-like protein
HCBLAFCG_02875 4.6e-93 yxiI S Protein of unknown function (DUF2716)
HCBLAFCG_02876 8.2e-138
HCBLAFCG_02877 1.8e-74 yxiG
HCBLAFCG_02878 6.4e-63
HCBLAFCG_02879 1.7e-84
HCBLAFCG_02880 1.5e-71 yxxG
HCBLAFCG_02881 0.0 wapA M COG3209 Rhs family protein
HCBLAFCG_02882 1.1e-164 yxxF EG EamA-like transporter family
HCBLAFCG_02883 1.2e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_02884 1.2e-121 1.14.11.45 E 2OG-Fe dioxygenase
HCBLAFCG_02885 1.2e-71 yxiE T Belongs to the universal stress protein A family
HCBLAFCG_02886 2.8e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCBLAFCG_02887 4.4e-306 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCBLAFCG_02888 4.1e-21 S Immunity protein 8
HCBLAFCG_02889 6.4e-216 S nuclease activity
HCBLAFCG_02890 4.7e-39 yxiC S Family of unknown function (DUF5344)
HCBLAFCG_02891 1.8e-17 S Domain of unknown function (DUF5082)
HCBLAFCG_02892 7.9e-279 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HCBLAFCG_02893 6.7e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HCBLAFCG_02894 1.3e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
HCBLAFCG_02895 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HCBLAFCG_02896 8.2e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HCBLAFCG_02897 3e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HCBLAFCG_02898 2.3e-251 lysP E amino acid
HCBLAFCG_02899 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HCBLAFCG_02900 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HCBLAFCG_02901 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HCBLAFCG_02902 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HCBLAFCG_02903 2e-152 yxxB S Domain of Unknown Function (DUF1206)
HCBLAFCG_02904 7.3e-195 eutH E Ethanolamine utilisation protein, EutH
HCBLAFCG_02905 8.4e-246 yxeQ S MmgE/PrpD family
HCBLAFCG_02906 3.6e-213 yxeP 3.5.1.47 E hydrolase activity
HCBLAFCG_02907 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HCBLAFCG_02908 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
HCBLAFCG_02909 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HCBLAFCG_02910 1.6e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBLAFCG_02911 9.2e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCBLAFCG_02912 4.1e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HCBLAFCG_02913 3.1e-150 yidA S hydrolases of the HAD superfamily
HCBLAFCG_02916 1.3e-20 yxeE
HCBLAFCG_02917 1.9e-16 yxeD
HCBLAFCG_02918 8.5e-69
HCBLAFCG_02919 1.9e-175 fhuD P ABC transporter
HCBLAFCG_02920 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HCBLAFCG_02921 0.0 yxdM V ABC transporter (permease)
HCBLAFCG_02922 9.4e-141 yxdL V ABC transporter, ATP-binding protein
HCBLAFCG_02923 4.8e-182 T PhoQ Sensor
HCBLAFCG_02924 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_02925 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HCBLAFCG_02926 2.1e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HCBLAFCG_02927 8.6e-167 iolH G Xylose isomerase-like TIM barrel
HCBLAFCG_02928 1.8e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HCBLAFCG_02929 1.8e-232 iolF EGP Major facilitator Superfamily
HCBLAFCG_02930 6.7e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HCBLAFCG_02931 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HCBLAFCG_02932 7.9e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HCBLAFCG_02933 8.7e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HCBLAFCG_02934 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCBLAFCG_02935 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HCBLAFCG_02936 8.3e-176 iolS C Aldo keto reductase
HCBLAFCG_02938 1.9e-47 yxcD S Protein of unknown function (DUF2653)
HCBLAFCG_02939 1.1e-245 csbC EGP Major facilitator Superfamily
HCBLAFCG_02940 0.0 htpG O Molecular chaperone. Has ATPase activity
HCBLAFCG_02942 1.3e-148 IQ Enoyl-(Acyl carrier protein) reductase
HCBLAFCG_02943 1.8e-209 yxbF K Bacterial regulatory proteins, tetR family
HCBLAFCG_02944 8.4e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HCBLAFCG_02945 8.8e-33 yxaI S membrane protein domain
HCBLAFCG_02946 4.3e-63 S Family of unknown function (DUF5391)
HCBLAFCG_02947 1.4e-75 yxaI S membrane protein domain
HCBLAFCG_02948 9.6e-225 P Protein of unknown function (DUF418)
HCBLAFCG_02949 7.1e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
HCBLAFCG_02950 3.9e-99 yxaF K Transcriptional regulator
HCBLAFCG_02951 9.5e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_02952 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HCBLAFCG_02953 5.2e-50 S LrgA family
HCBLAFCG_02954 3.4e-118 yxaC M effector of murein hydrolase
HCBLAFCG_02955 1e-190 yxaB GM Polysaccharide pyruvyl transferase
HCBLAFCG_02956 7.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HCBLAFCG_02957 1.2e-126 gntR K transcriptional
HCBLAFCG_02958 1.7e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HCBLAFCG_02959 5e-230 gntP EG COG2610 H gluconate symporter and related permeases
HCBLAFCG_02960 3.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCBLAFCG_02961 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HCBLAFCG_02962 2.5e-286 ahpF O Alkyl hydroperoxide reductase
HCBLAFCG_02963 1.2e-188 wgaE S Polysaccharide pyruvyl transferase
HCBLAFCG_02964 1.2e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCBLAFCG_02965 5.4e-127 yydK K Transcriptional regulator
HCBLAFCG_02966 8.4e-12
HCBLAFCG_02967 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HCBLAFCG_02968 1.1e-70 L ATPase involved in DNA repair
HCBLAFCG_02969 4.6e-12
HCBLAFCG_02970 3.2e-23
HCBLAFCG_02971 2.6e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCBLAFCG_02972 1.4e-09 S YyzF-like protein
HCBLAFCG_02973 2.8e-67
HCBLAFCG_02974 6.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HCBLAFCG_02976 3.7e-30 yycQ S Protein of unknown function (DUF2651)
HCBLAFCG_02977 4.9e-210 yycP
HCBLAFCG_02978 8e-129 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HCBLAFCG_02979 6.4e-84 yycN 2.3.1.128 K Acetyltransferase
HCBLAFCG_02980 4.7e-186 S aspartate phosphatase
HCBLAFCG_02982 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HCBLAFCG_02983 9.7e-261 rocE E amino acid
HCBLAFCG_02984 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HCBLAFCG_02985 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HCBLAFCG_02986 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCBLAFCG_02987 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HCBLAFCG_02988 6.2e-154 yycI S protein conserved in bacteria
HCBLAFCG_02989 2e-258 yycH S protein conserved in bacteria
HCBLAFCG_02990 0.0 vicK 2.7.13.3 T Histidine kinase
HCBLAFCG_02991 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_02996 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCBLAFCG_02997 1.3e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBLAFCG_02998 2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HCBLAFCG_02999 3.3e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HCBLAFCG_03001 1.9e-15 yycC K YycC-like protein
HCBLAFCG_03002 1.9e-89 yeaN P COG2807 Cyanate permease
HCBLAFCG_03003 4.9e-117 yeaN P COG2807 Cyanate permease
HCBLAFCG_03004 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCBLAFCG_03005 2.2e-73 rplI J binds to the 23S rRNA
HCBLAFCG_03006 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HCBLAFCG_03007 2.9e-160 yybS S membrane
HCBLAFCG_03009 3.9e-84 cotF M Spore coat protein
HCBLAFCG_03010 1.4e-68 ydeP3 K Transcriptional regulator
HCBLAFCG_03011 4.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HCBLAFCG_03012 1.6e-60
HCBLAFCG_03014 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HCBLAFCG_03015 1.1e-109 K TipAS antibiotic-recognition domain
HCBLAFCG_03016 1.6e-124
HCBLAFCG_03017 7.2e-65 yybH S SnoaL-like domain
HCBLAFCG_03018 1.7e-119 yybG S Pentapeptide repeat-containing protein
HCBLAFCG_03019 1.7e-216 ynfM EGP Major facilitator Superfamily
HCBLAFCG_03020 5.8e-163 yybE K Transcriptional regulator
HCBLAFCG_03021 2e-79 yjcF S Acetyltransferase (GNAT) domain
HCBLAFCG_03022 3e-76 yybC
HCBLAFCG_03023 3.3e-126 S Metallo-beta-lactamase superfamily
HCBLAFCG_03024 5.6e-77 yybA 2.3.1.57 K transcriptional
HCBLAFCG_03025 6.5e-70 yjcF S Acetyltransferase (GNAT) domain
HCBLAFCG_03026 2.5e-96 yyaS S Membrane
HCBLAFCG_03027 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
HCBLAFCG_03028 1.3e-65 yyaQ S YjbR
HCBLAFCG_03029 1e-104 yyaP 1.5.1.3 H RibD C-terminal domain
HCBLAFCG_03033 3.9e-22 yyaR K acetyltransferase
HCBLAFCG_03034 2.5e-150 eaeH M Domain of Unknown Function (DUF1259)
HCBLAFCG_03035 1.8e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HCBLAFCG_03036 1.4e-57 mpr 3.4.21.19 E Trypsin-like serine protease
HCBLAFCG_03037 2.9e-53 L Recombinase
HCBLAFCG_03039 7.8e-61
HCBLAFCG_03041 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HCBLAFCG_03042 3.6e-168 yyaK S CAAX protease self-immunity
HCBLAFCG_03043 3.2e-245 EGP Major facilitator superfamily
HCBLAFCG_03044 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HCBLAFCG_03045 1.9e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBLAFCG_03046 7.5e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HCBLAFCG_03047 4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
HCBLAFCG_03048 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCBLAFCG_03049 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCBLAFCG_03050 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HCBLAFCG_03051 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCBLAFCG_03052 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCBLAFCG_03053 2.3e-33 yyzM S protein conserved in bacteria
HCBLAFCG_03054 8.1e-177 yyaD S Membrane
HCBLAFCG_03055 2.8e-111 yyaC S Sporulation protein YyaC
HCBLAFCG_03056 6e-149 spo0J K Belongs to the ParB family
HCBLAFCG_03057 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HCBLAFCG_03058 5.7e-74 S Bacterial PH domain
HCBLAFCG_03059 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HCBLAFCG_03060 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HCBLAFCG_03061 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCBLAFCG_03062 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCBLAFCG_03063 6.5e-108 jag S single-stranded nucleic acid binding R3H
HCBLAFCG_03064 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCBLAFCG_03065 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCBLAFCG_03066 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCBLAFCG_03067 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCBLAFCG_03068 2.4e-33 yaaA S S4 domain
HCBLAFCG_03069 9.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCBLAFCG_03070 1.8e-37 yaaB S Domain of unknown function (DUF370)
HCBLAFCG_03071 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCBLAFCG_03072 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCBLAFCG_03073 1.4e-14 S Protein of unknown function (DUF1433)
HCBLAFCG_03074 9.5e-29 S Domain of unknown function (DUF4917)
HCBLAFCG_03075 1.9e-12
HCBLAFCG_03076 5.8e-53 S Protein of unknown function (DUF4238)
HCBLAFCG_03077 2.7e-09 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HCBLAFCG_03079 1.7e-210 yjcL S Protein of unknown function (DUF819)
HCBLAFCG_03080 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
HCBLAFCG_03081 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HCBLAFCG_03082 5.5e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HCBLAFCG_03083 1e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
HCBLAFCG_03084 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HCBLAFCG_03085 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBLAFCG_03086 1.7e-38
HCBLAFCG_03087 0.0 yjcD 3.6.4.12 L DNA helicase
HCBLAFCG_03088 2.9e-38 spoVIF S Stage VI sporulation protein F
HCBLAFCG_03091 1.9e-56 yjcA S Protein of unknown function (DUF1360)
HCBLAFCG_03092 1.4e-23 cotV S Spore Coat Protein X and V domain
HCBLAFCG_03093 1.4e-10 cotW
HCBLAFCG_03094 1.4e-38 cotX S Spore Coat Protein X and V domain
HCBLAFCG_03095 3.4e-96 cotY S Spore coat protein Z
HCBLAFCG_03096 5.2e-83 cotZ S Spore coat protein
HCBLAFCG_03097 5.9e-54 yjbX S Spore coat protein
HCBLAFCG_03098 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HCBLAFCG_03099 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCBLAFCG_03100 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HCBLAFCG_03101 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HCBLAFCG_03102 6.7e-30 thiS H thiamine diphosphate biosynthetic process
HCBLAFCG_03103 1.4e-217 thiO 1.4.3.19 E Glycine oxidase
HCBLAFCG_03104 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HCBLAFCG_03105 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HCBLAFCG_03106 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCBLAFCG_03107 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HCBLAFCG_03108 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCBLAFCG_03109 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCBLAFCG_03110 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HCBLAFCG_03111 2.1e-61 yjbL S Belongs to the UPF0738 family
HCBLAFCG_03112 7.1e-101 yjbK S protein conserved in bacteria
HCBLAFCG_03113 2.4e-85 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HCBLAFCG_03114 3.7e-72 yjbI S Bacterial-like globin
HCBLAFCG_03115 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HCBLAFCG_03116 1.8e-20
HCBLAFCG_03117 0.0 pepF E oligoendopeptidase F
HCBLAFCG_03118 2.8e-221 yjbF S Competence protein
HCBLAFCG_03119 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HCBLAFCG_03120 1.3e-111 yjbE P Integral membrane protein TerC family
HCBLAFCG_03121 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCBLAFCG_03122 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBLAFCG_03123 2e-203 yjbB EGP Major Facilitator Superfamily
HCBLAFCG_03124 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HCBLAFCG_03125 1.7e-196 oppD P Belongs to the ABC transporter superfamily
HCBLAFCG_03126 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCBLAFCG_03127 1.8e-162 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCBLAFCG_03128 1.2e-305 oppA E ABC transporter substrate-binding protein
HCBLAFCG_03129 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HCBLAFCG_03130 1.9e-146 yjbA S Belongs to the UPF0736 family
HCBLAFCG_03131 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCBLAFCG_03132 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCBLAFCG_03133 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HCBLAFCG_03134 1.4e-184 appF E Belongs to the ABC transporter superfamily
HCBLAFCG_03135 1.8e-184 appD P Belongs to the ABC transporter superfamily
HCBLAFCG_03136 7.8e-151 yjaZ O Zn-dependent protease
HCBLAFCG_03137 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCBLAFCG_03138 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCBLAFCG_03139 5e-21 yjzB
HCBLAFCG_03140 7.3e-26 comZ S ComZ
HCBLAFCG_03141 4.2e-183 med S Transcriptional activator protein med
HCBLAFCG_03142 2.6e-100 yjaV
HCBLAFCG_03143 6.2e-142 yjaU I carboxylic ester hydrolase activity
HCBLAFCG_03144 6.6e-16 yjzD S Protein of unknown function (DUF2929)
HCBLAFCG_03145 9.5e-28 yjzC S YjzC-like protein
HCBLAFCG_03146 3.3e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCBLAFCG_03147 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HCBLAFCG_03148 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCBLAFCG_03149 2.1e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HCBLAFCG_03150 1.2e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HCBLAFCG_03151 3.4e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HCBLAFCG_03152 8.1e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HCBLAFCG_03153 1.7e-88 norB G Major Facilitator Superfamily
HCBLAFCG_03154 3.4e-269 yitY C D-arabinono-1,4-lactone oxidase
HCBLAFCG_03155 1.5e-22 pilT S Proteolipid membrane potential modulator
HCBLAFCG_03156 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HCBLAFCG_03157 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HCBLAFCG_03158 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HCBLAFCG_03160 2.8e-17 S Protein of unknown function (DUF3813)
HCBLAFCG_03161 5e-73 ipi S Intracellular proteinase inhibitor
HCBLAFCG_03162 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HCBLAFCG_03163 8.4e-159 yitS S protein conserved in bacteria
HCBLAFCG_03164 2.7e-307 nprB 3.4.24.28 E Peptidase M4
HCBLAFCG_03165 1.4e-44 yitR S Domain of unknown function (DUF3784)
HCBLAFCG_03166 8.6e-94
HCBLAFCG_03167 1.5e-58 K Transcriptional regulator PadR-like family
HCBLAFCG_03168 1.5e-97 S Sporulation delaying protein SdpA
HCBLAFCG_03169 1.4e-170
HCBLAFCG_03170 8.5e-94
HCBLAFCG_03171 4e-161 cvfB S protein conserved in bacteria
HCBLAFCG_03172 8.6e-55 yajQ S Belongs to the UPF0234 family
HCBLAFCG_03173 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HCBLAFCG_03174 1.3e-81 yjcF S Acetyltransferase (GNAT) domain
HCBLAFCG_03175 1.2e-157 yitH K Acetyltransferase (GNAT) domain
HCBLAFCG_03176 1.5e-228 yitG EGP Major facilitator Superfamily
HCBLAFCG_03177 7.8e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HCBLAFCG_03178 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCBLAFCG_03179 5.4e-141 yitD 4.4.1.19 S synthase
HCBLAFCG_03180 3.3e-121 comB 3.1.3.71 H Belongs to the ComB family
HCBLAFCG_03181 1e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HCBLAFCG_03182 2.7e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HCBLAFCG_03183 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HCBLAFCG_03184 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HCBLAFCG_03185 5.7e-35 mcbG S Pentapeptide repeats (9 copies)
HCBLAFCG_03186 9.9e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCBLAFCG_03187 1.9e-107 argO S Lysine exporter protein LysE YggA
HCBLAFCG_03188 8.2e-93 yisT S DinB family
HCBLAFCG_03189 6.3e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HCBLAFCG_03190 6.1e-180 purR K helix_turn _helix lactose operon repressor
HCBLAFCG_03191 1.6e-160 yisR K Transcriptional regulator
HCBLAFCG_03192 4e-243 yisQ V Mate efflux family protein
HCBLAFCG_03193 2.7e-146 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HCBLAFCG_03194 2.1e-88 yizA S Damage-inducible protein DinB
HCBLAFCG_03195 0.0 asnO 6.3.5.4 E Asparagine synthase
HCBLAFCG_03196 4.8e-102 yisN S Protein of unknown function (DUF2777)
HCBLAFCG_03197 0.0 wprA O Belongs to the peptidase S8 family
HCBLAFCG_03198 5.1e-57 yisL S UPF0344 protein
HCBLAFCG_03199 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HCBLAFCG_03200 1.3e-173 cotH M Spore Coat
HCBLAFCG_03201 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HCBLAFCG_03202 1.9e-33 gerPA S Spore germination protein
HCBLAFCG_03203 4e-34 gerPB S cell differentiation
HCBLAFCG_03204 5.3e-54 gerPC S Spore germination protein
HCBLAFCG_03205 3.1e-23 gerPD S Spore germination protein
HCBLAFCG_03206 5.3e-63 gerPE S Spore germination protein GerPE
HCBLAFCG_03207 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HCBLAFCG_03208 2.1e-48 yisB V COG1403 Restriction endonuclease
HCBLAFCG_03209 0.0 sbcC L COG0419 ATPase involved in DNA repair
HCBLAFCG_03210 2.6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HCBLAFCG_03211 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HCBLAFCG_03212 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HCBLAFCG_03213 1.9e-77 yhjR S Rubrerythrin
HCBLAFCG_03214 8.6e-27 yhjQ C COG1145 Ferredoxin
HCBLAFCG_03215 0.0 S Sugar transport-related sRNA regulator N-term
HCBLAFCG_03216 3.3e-209 EGP Transmembrane secretion effector
HCBLAFCG_03217 4.2e-201 abrB S membrane
HCBLAFCG_03218 3.2e-186 yhjM 5.1.1.1 K Transcriptional regulator
HCBLAFCG_03219 6.6e-251 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HCBLAFCG_03220 1.3e-159 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HCBLAFCG_03221 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HCBLAFCG_03222 2.2e-213 glcP G Major Facilitator Superfamily
HCBLAFCG_03223 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HCBLAFCG_03224 2e-280 yhjG CH FAD binding domain
HCBLAFCG_03225 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HCBLAFCG_03226 5.9e-109 yhjE S SNARE associated Golgi protein
HCBLAFCG_03227 3.3e-59 yhjD
HCBLAFCG_03228 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HCBLAFCG_03229 8.8e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCBLAFCG_03230 2.8e-39 yhjA S Excalibur calcium-binding domain
HCBLAFCG_03231 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
HCBLAFCG_03232 9.3e-109 comK K Competence transcription factor
HCBLAFCG_03233 1.3e-32 yhzC S IDEAL
HCBLAFCG_03234 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_03235 4e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HCBLAFCG_03236 8.3e-182 hemAT NT chemotaxis protein
HCBLAFCG_03237 5e-91 bioY S BioY family
HCBLAFCG_03238 6.2e-271 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HCBLAFCG_03239 6.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
HCBLAFCG_03240 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HCBLAFCG_03241 4.3e-159 yfmC M Periplasmic binding protein
HCBLAFCG_03242 3.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
HCBLAFCG_03243 7.3e-77 VY92_01935 K acetyltransferase
HCBLAFCG_03244 1.2e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HCBLAFCG_03245 1.2e-238 yhfN 3.4.24.84 O Peptidase M48
HCBLAFCG_03246 1.9e-65 yhfM
HCBLAFCG_03247 2.7e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HCBLAFCG_03248 5e-111 yhfK GM NmrA-like family
HCBLAFCG_03249 6.3e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HCBLAFCG_03250 5.2e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HCBLAFCG_03251 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCBLAFCG_03252 4.1e-71 3.4.13.21 S ASCH
HCBLAFCG_03253 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HCBLAFCG_03254 1.1e-133 yhfC S Putative membrane peptidase family (DUF2324)
HCBLAFCG_03255 5.3e-181 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCBLAFCG_03256 4.1e-224 yhgE S YhgE Pip N-terminal domain protein
HCBLAFCG_03257 5.4e-101 yhgD K Transcriptional regulator
HCBLAFCG_03258 8.5e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HCBLAFCG_03259 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HCBLAFCG_03260 2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HCBLAFCG_03261 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCBLAFCG_03262 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HCBLAFCG_03263 3.9e-32 1.15.1.2 C Rubrerythrin
HCBLAFCG_03264 3.2e-240 yhfA C membrane
HCBLAFCG_03265 7e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HCBLAFCG_03266 6.9e-114 ecsC S EcsC protein family
HCBLAFCG_03267 8.6e-213 ecsB U ABC transporter
HCBLAFCG_03268 4.6e-137 ecsA V transporter (ATP-binding protein)
HCBLAFCG_03269 5.2e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HCBLAFCG_03270 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HCBLAFCG_03271 3.6e-80 trpP S Tryptophan transporter TrpP
HCBLAFCG_03272 5.4e-21
HCBLAFCG_03273 7e-39 yhaH S YtxH-like protein
HCBLAFCG_03274 1e-113 hpr K Negative regulator of protease production and sporulation
HCBLAFCG_03275 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HCBLAFCG_03276 8.7e-90 yhaK S Putative zincin peptidase
HCBLAFCG_03277 4.1e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCBLAFCG_03278 1.6e-21 yhaL S Sporulation protein YhaL
HCBLAFCG_03279 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HCBLAFCG_03280 0.0 yhaN L AAA domain
HCBLAFCG_03281 2.8e-224 yhaO L DNA repair exonuclease
HCBLAFCG_03282 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HCBLAFCG_03283 2.6e-166 yhaQ S ABC transporter, ATP-binding protein
HCBLAFCG_03284 2.4e-26 S YhzD-like protein
HCBLAFCG_03285 9.4e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HCBLAFCG_03287 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HCBLAFCG_03288 2.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HCBLAFCG_03289 4.6e-293 hemZ H coproporphyrinogen III oxidase
HCBLAFCG_03290 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HCBLAFCG_03291 2.9e-204 yhaZ L DNA alkylation repair enzyme
HCBLAFCG_03292 9.5e-48 yheA S Belongs to the UPF0342 family
HCBLAFCG_03293 2.2e-202 yheB S Belongs to the UPF0754 family
HCBLAFCG_03294 4.3e-216 yheC HJ YheC/D like ATP-grasp
HCBLAFCG_03295 1.1e-264 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HCBLAFCG_03296 3.8e-36 yheE S Family of unknown function (DUF5342)
HCBLAFCG_03297 6.3e-28 sspB S spore protein
HCBLAFCG_03298 7.6e-109 yheG GM NAD(P)H-binding
HCBLAFCG_03299 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCBLAFCG_03300 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCBLAFCG_03301 1.7e-83 nhaX T Belongs to the universal stress protein A family
HCBLAFCG_03302 1.5e-229 nhaC C Na H antiporter
HCBLAFCG_03303 4e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HCBLAFCG_03304 8.7e-148 yheN G deacetylase
HCBLAFCG_03305 2.5e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HCBLAFCG_03306 5.6e-203 yhdY M Mechanosensitive ion channel
HCBLAFCG_03308 2e-132 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCBLAFCG_03309 3.1e-63 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCBLAFCG_03310 2.5e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCBLAFCG_03311 1.4e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HCBLAFCG_03312 1.4e-220 yhdR 2.6.1.1 E Aminotransferase
HCBLAFCG_03313 4.1e-74 cueR K transcriptional
HCBLAFCG_03314 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HCBLAFCG_03315 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HCBLAFCG_03316 5.7e-191 yhdN C Aldo keto reductase
HCBLAFCG_03317 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HCBLAFCG_03318 6.6e-201 yhdL S Sigma factor regulator N-terminal
HCBLAFCG_03319 8.1e-45 yhdK S Sigma-M inhibitor protein
HCBLAFCG_03320 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBLAFCG_03321 8.2e-268 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCBLAFCG_03322 9.7e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HCBLAFCG_03323 3.4e-250 yhdG E amino acid
HCBLAFCG_03324 6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_03325 1e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
HCBLAFCG_03326 3.8e-162 citR K Transcriptional regulator
HCBLAFCG_03327 5.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HCBLAFCG_03328 1.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HCBLAFCG_03329 6.3e-276 ycgB S Stage V sporulation protein R
HCBLAFCG_03330 8.1e-237 ygxB M Conserved TM helix
HCBLAFCG_03331 2.3e-75 nsrR K Transcriptional regulator
HCBLAFCG_03332 1.8e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HCBLAFCG_03333 1.8e-53 yhdC S Protein of unknown function (DUF3889)
HCBLAFCG_03334 1.2e-38 yhdB S YhdB-like protein
HCBLAFCG_03335 1.6e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
HCBLAFCG_03336 2.2e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCBLAFCG_03337 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
HCBLAFCG_03338 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HCBLAFCG_03339 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HCBLAFCG_03340 3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCBLAFCG_03341 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HCBLAFCG_03342 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HCBLAFCG_03343 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCBLAFCG_03344 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HCBLAFCG_03345 1e-119 yhcW 5.4.2.6 S hydrolase
HCBLAFCG_03346 9.9e-68 yhcV S COG0517 FOG CBS domain
HCBLAFCG_03347 2.1e-67 yhcU S Family of unknown function (DUF5365)
HCBLAFCG_03348 1.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCBLAFCG_03349 4.2e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HCBLAFCG_03350 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HCBLAFCG_03351 5.2e-100 yhcQ M Spore coat protein
HCBLAFCG_03352 1.2e-139 yhcP
HCBLAFCG_03353 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCBLAFCG_03354 2.9e-41 yhcM
HCBLAFCG_03355 4.1e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCBLAFCG_03356 9.3e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HCBLAFCG_03357 2.8e-151 metQ M Belongs to the nlpA lipoprotein family
HCBLAFCG_03358 1e-30 cspB K Cold-shock protein
HCBLAFCG_03359 1.6e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HCBLAFCG_03360 5.5e-164 yhcH V ABC transporter, ATP-binding protein
HCBLAFCG_03361 4.4e-121 yhcG V ABC transporter, ATP-binding protein
HCBLAFCG_03362 1.9e-59 yhcF K Transcriptional regulator
HCBLAFCG_03363 3e-54
HCBLAFCG_03364 2.8e-37 yhcC
HCBLAFCG_03365 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HCBLAFCG_03366 3.1e-271 yhcA EGP Major facilitator Superfamily
HCBLAFCG_03367 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HCBLAFCG_03368 2.2e-76 yhbI K DNA-binding transcription factor activity
HCBLAFCG_03369 2.5e-225 yhbH S Belongs to the UPF0229 family
HCBLAFCG_03370 0.0 prkA T Ser protein kinase
HCBLAFCG_03371 9.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HCBLAFCG_03372 7.8e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HCBLAFCG_03373 7.9e-109 yhbD K Protein of unknown function (DUF4004)
HCBLAFCG_03374 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCBLAFCG_03375 7e-175 yhbB S Putative amidase domain
HCBLAFCG_03376 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HCBLAFCG_03377 7.9e-114 yhzB S B3/4 domain
HCBLAFCG_03379 4.4e-29 K Transcriptional regulator
HCBLAFCG_03380 4.1e-78 ygaO
HCBLAFCG_03381 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCBLAFCG_03383 2.6e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HCBLAFCG_03384 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCBLAFCG_03385 2.1e-169 ssuA M Sulfonate ABC transporter
HCBLAFCG_03386 3.3e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HCBLAFCG_03387 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HCBLAFCG_03389 5.3e-264 ygaK C Berberine and berberine like
HCBLAFCG_03390 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HCBLAFCG_03391 2.2e-128 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HCBLAFCG_03392 3.4e-26
HCBLAFCG_03393 2.7e-143 spo0M S COG4326 Sporulation control protein
HCBLAFCG_03397 2e-08
HCBLAFCG_03403 7.8e-08
HCBLAFCG_03405 5.3e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HCBLAFCG_03406 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HCBLAFCG_03407 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HCBLAFCG_03408 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HCBLAFCG_03409 5.2e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCBLAFCG_03410 0.0 ydiF S ABC transporter
HCBLAFCG_03411 7.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HCBLAFCG_03412 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCBLAFCG_03413 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HCBLAFCG_03414 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HCBLAFCG_03415 1.5e-26 ydiK S Domain of unknown function (DUF4305)
HCBLAFCG_03416 7.9e-129 ydiL S CAAX protease self-immunity
HCBLAFCG_03417 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCBLAFCG_03418 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCBLAFCG_03420 2.6e-32 K helix_turn_helix, arabinose operon control protein
HCBLAFCG_03422 4.4e-53 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydrobiopterin synthase
HCBLAFCG_03423 4.1e-77 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HCBLAFCG_03424 6.1e-87 O Carbamoyltransferase C-terminus
HCBLAFCG_03425 1e-56 folE 3.5.4.16 H GTP cyclohydrolase I
HCBLAFCG_03427 1.7e-91 ocd 1.5.1.51, 2.5.1.140, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HCBLAFCG_03428 3.8e-107 cysM 2.5.1.140 E Pyridoxal-phosphate dependent enzyme
HCBLAFCG_03429 6.6e-64 Q Belongs to the ATP-dependent AMP-binding enzyme family
HCBLAFCG_03430 2.4e-19 queC 6.3.4.20 H Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HCBLAFCG_03431 9.2e-60 dpaL 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HCBLAFCG_03432 8.7e-33 GT2,GT4 V Glycosyl transferase, family 2
HCBLAFCG_03433 1.2e-196 V ABC transporter, ATP-binding protein
HCBLAFCG_03434 0.0 K NB-ARC domain
HCBLAFCG_03435 1.6e-199 gutB 1.1.1.14 E Dehydrogenase
HCBLAFCG_03436 1.9e-253 gutA G MFS/sugar transport protein
HCBLAFCG_03437 5.2e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HCBLAFCG_03438 8.7e-114 pspA KT Phage shock protein A
HCBLAFCG_03439 2.8e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCBLAFCG_03440 4.3e-130 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HCBLAFCG_03441 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
HCBLAFCG_03442 2.5e-149 S Ion transport 2 domain protein
HCBLAFCG_03443 1.7e-257 iolT EGP Major facilitator Superfamily
HCBLAFCG_03444 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HCBLAFCG_03445 4.5e-64 ydjM M Lytic transglycolase
HCBLAFCG_03446 5.3e-155 ydjN U Involved in the tonB-independent uptake of proteins
HCBLAFCG_03448 3.1e-158 ydjP I Alpha/beta hydrolase family
HCBLAFCG_03449 4e-176 yeaA S Protein of unknown function (DUF4003)
HCBLAFCG_03450 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HCBLAFCG_03451 9.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HCBLAFCG_03452 1.9e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCBLAFCG_03453 3.9e-176 yeaC S COG0714 MoxR-like ATPases
HCBLAFCG_03454 4.4e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HCBLAFCG_03455 0.0 yebA E COG1305 Transglutaminase-like enzymes
HCBLAFCG_03456 1.9e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HCBLAFCG_03457 3e-211 pbuG S permease
HCBLAFCG_03458 2.3e-118 yebC M Membrane
HCBLAFCG_03460 4e-93 yebE S UPF0316 protein
HCBLAFCG_03461 8e-28 yebG S NETI protein
HCBLAFCG_03462 9.7e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCBLAFCG_03463 2.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCBLAFCG_03464 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCBLAFCG_03465 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HCBLAFCG_03466 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBLAFCG_03467 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBLAFCG_03468 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBLAFCG_03469 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCBLAFCG_03470 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HCBLAFCG_03471 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCBLAFCG_03472 1.9e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HCBLAFCG_03473 3.2e-231 purD 6.3.4.13 F Belongs to the GARS family
HCBLAFCG_03474 7.3e-71 K helix_turn_helix ASNC type
HCBLAFCG_03475 5.7e-228 yjeH E Amino acid permease
HCBLAFCG_03476 2.7e-27 S Protein of unknown function (DUF2892)
HCBLAFCG_03477 0.0 yerA 3.5.4.2 F adenine deaminase
HCBLAFCG_03478 6.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
HCBLAFCG_03479 4.8e-51 yerC S protein conserved in bacteria
HCBLAFCG_03480 2.6e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HCBLAFCG_03481 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HCBLAFCG_03482 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HCBLAFCG_03483 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCBLAFCG_03484 1.6e-219 camS S COG4851 Protein involved in sex pheromone biosynthesis
HCBLAFCG_03485 1e-195 yerI S homoserine kinase type II (protein kinase fold)
HCBLAFCG_03486 1.6e-123 sapB S MgtC SapB transporter
HCBLAFCG_03487 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCBLAFCG_03488 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCBLAFCG_03489 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCBLAFCG_03490 1.2e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCBLAFCG_03491 1.5e-147 yerO K Transcriptional regulator
HCBLAFCG_03492 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HCBLAFCG_03493 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HCBLAFCG_03494 6.4e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCBLAFCG_03495 1.1e-18 L DNA binding domain protein, excisionase family
HCBLAFCG_03496 9e-101 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HCBLAFCG_03497 7.1e-126 dcm 2.1.1.37, 2.1.1.72 L C-5 cytosine-specific DNA methylase
HCBLAFCG_03498 7.2e-218 V AAA domain (dynein-related subfamily)
HCBLAFCG_03499 6.7e-257 L LlaJI restriction endonuclease
HCBLAFCG_03500 2.2e-185 E Zn peptidase
HCBLAFCG_03501 6.1e-154 E Zn peptidase
HCBLAFCG_03502 2.1e-109
HCBLAFCG_03503 1.1e-270
HCBLAFCG_03504 8.7e-148
HCBLAFCG_03506 8.8e-50 S response regulator aspartate phosphatase
HCBLAFCG_03508 3e-18 S Aspartate phosphatase response regulator
HCBLAFCG_03510 8.9e-30 S Colicin immunity protein / pyocin immunity protein
HCBLAFCG_03512 1.1e-77 S Protein of unknown function, DUF600
HCBLAFCG_03513 1.6e-55 S Protein of unknown function, DUF600
HCBLAFCG_03514 5.5e-51 S Protein of unknown function, DUF600
HCBLAFCG_03515 0.0 L nucleic acid phosphodiester bond hydrolysis
HCBLAFCG_03516 1.8e-118 3.4.24.40 CO amine dehydrogenase activity
HCBLAFCG_03517 4.4e-49
HCBLAFCG_03518 1.5e-208 S Tetratricopeptide repeat
HCBLAFCG_03520 2.7e-126 yeeN K transcriptional regulatory protein
HCBLAFCG_03522 1.8e-99 dhaR3 K Transcriptional regulator
HCBLAFCG_03523 6.9e-80 yesE S SnoaL-like domain
HCBLAFCG_03524 7.1e-150 yesF GM NAD(P)H-binding
HCBLAFCG_03525 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HCBLAFCG_03526 1.5e-45 cotJB S CotJB protein
HCBLAFCG_03527 5.2e-104 cotJC P Spore Coat
HCBLAFCG_03528 3.3e-100 yesJ K Acetyltransferase (GNAT) family
HCBLAFCG_03530 1.2e-101 yesL S Protein of unknown function, DUF624
HCBLAFCG_03531 0.0 yesM 2.7.13.3 T Histidine kinase
HCBLAFCG_03532 4e-201 yesN K helix_turn_helix, arabinose operon control protein
HCBLAFCG_03533 1.5e-247 yesO G Bacterial extracellular solute-binding protein
HCBLAFCG_03534 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
HCBLAFCG_03535 2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
HCBLAFCG_03536 6.6e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HCBLAFCG_03537 0.0 yesS K Transcriptional regulator
HCBLAFCG_03538 5.5e-132 E GDSL-like Lipase/Acylhydrolase
HCBLAFCG_03539 2.1e-128 yesU S Domain of unknown function (DUF1961)
HCBLAFCG_03540 2e-112 yesV S Protein of unknown function, DUF624
HCBLAFCG_03541 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HCBLAFCG_03542 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HCBLAFCG_03543 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
HCBLAFCG_03544 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HCBLAFCG_03545 0.0 yetA
HCBLAFCG_03546 1.1e-289 lplA G Bacterial extracellular solute-binding protein
HCBLAFCG_03547 1.6e-174 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HCBLAFCG_03548 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HCBLAFCG_03549 1.2e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HCBLAFCG_03550 8.8e-122 yetF S membrane
HCBLAFCG_03551 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HCBLAFCG_03552 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBLAFCG_03553 2.4e-34
HCBLAFCG_03554 1.3e-143 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HCBLAFCG_03555 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HCBLAFCG_03556 2e-104 yetJ S Belongs to the BI1 family
HCBLAFCG_03557 1.4e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
HCBLAFCG_03558 9.8e-208 yetM CH FAD binding domain
HCBLAFCG_03559 3.6e-199 yetN S Protein of unknown function (DUF3900)
HCBLAFCG_03560 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HCBLAFCG_03561 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HCBLAFCG_03562 7.4e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
HCBLAFCG_03563 2.1e-171 yfnG 4.2.1.45 M dehydratase
HCBLAFCG_03564 1e-178 yfnF M Nucleotide-diphospho-sugar transferase
HCBLAFCG_03565 1.4e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HCBLAFCG_03566 5e-189 yfnD M Nucleotide-diphospho-sugar transferase
HCBLAFCG_03567 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
HCBLAFCG_03568 3.4e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCBLAFCG_03569 6.4e-241 yfnA E amino acid
HCBLAFCG_03570 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCBLAFCG_03571 1.1e-113 yfmS NT chemotaxis protein
HCBLAFCG_03572 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HCBLAFCG_03573 2.6e-74 yfmQ S Uncharacterised protein from bacillus cereus group
HCBLAFCG_03574 1.4e-69 yfmP K transcriptional
HCBLAFCG_03575 2.8e-208 yfmO EGP Major facilitator Superfamily
HCBLAFCG_03576 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HCBLAFCG_03577 1.7e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HCBLAFCG_03578 1.5e-77 yfmK 2.3.1.128 K acetyltransferase
HCBLAFCG_03579 2.7e-188 yfmJ S N-terminal domain of oxidoreductase
HCBLAFCG_03580 7.4e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HCBLAFCG_03581 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_03582 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_03583 3.9e-165 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HCBLAFCG_03584 2.9e-24 S Protein of unknown function (DUF3212)
HCBLAFCG_03585 7.6e-58 yflT S Heat induced stress protein YflT
HCBLAFCG_03586 1.2e-238 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HCBLAFCG_03587 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
HCBLAFCG_03588 1.5e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HCBLAFCG_03589 8.9e-119 citT T response regulator
HCBLAFCG_03590 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
HCBLAFCG_03591 1.9e-226 citM C Citrate transporter
HCBLAFCG_03592 2.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HCBLAFCG_03593 2.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HCBLAFCG_03594 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HCBLAFCG_03595 6.4e-122 yflK S protein conserved in bacteria
HCBLAFCG_03596 4e-18 yflJ S Protein of unknown function (DUF2639)
HCBLAFCG_03597 4.1e-19 yflI
HCBLAFCG_03598 5.3e-50 yflH S Protein of unknown function (DUF3243)
HCBLAFCG_03599 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HCBLAFCG_03600 2.6e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HCBLAFCG_03601 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HCBLAFCG_03602 6e-67 yhdN S Domain of unknown function (DUF1992)
HCBLAFCG_03603 1.3e-249 agcS_1 E Sodium alanine symporter
HCBLAFCG_03604 2.3e-193 E Spore germination protein
HCBLAFCG_03606 5.1e-207 yfkR S spore germination
HCBLAFCG_03607 2.1e-280 yfkQ EG Spore germination protein
HCBLAFCG_03608 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCBLAFCG_03609 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HCBLAFCG_03610 1.8e-133 treR K transcriptional
HCBLAFCG_03611 1.1e-124 yfkO C nitroreductase
HCBLAFCG_03612 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HCBLAFCG_03613 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
HCBLAFCG_03614 1.2e-203 ydiM EGP Major facilitator Superfamily
HCBLAFCG_03615 1.3e-28 yfkK S Belongs to the UPF0435 family
HCBLAFCG_03616 3.5e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCBLAFCG_03617 2.4e-50 yfkI S gas vesicle protein
HCBLAFCG_03618 4.8e-143 yihY S Belongs to the UPF0761 family
HCBLAFCG_03619 5e-08
HCBLAFCG_03620 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HCBLAFCG_03621 1.8e-182 cax P COG0387 Ca2 H antiporter
HCBLAFCG_03622 1.2e-146 yfkD S YfkD-like protein
HCBLAFCG_03623 6e-149 yfkC M Mechanosensitive ion channel
HCBLAFCG_03624 5.4e-222 yfkA S YfkB-like domain
HCBLAFCG_03625 1.1e-26 yfjT
HCBLAFCG_03626 2.6e-154 pdaA G deacetylase
HCBLAFCG_03627 2.7e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HCBLAFCG_03628 1.7e-184 corA P Mediates influx of magnesium ions
HCBLAFCG_03629 2.9e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HCBLAFCG_03630 3.8e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCBLAFCG_03631 1.1e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCBLAFCG_03632 9.6e-85 yfjM S Psort location Cytoplasmic, score
HCBLAFCG_03633 6.6e-29 yfjL
HCBLAFCG_03634 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCBLAFCG_03635 3.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCBLAFCG_03636 3.5e-195 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCBLAFCG_03637 1.5e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCBLAFCG_03638 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HCBLAFCG_03639 9.8e-25 sspH S Belongs to the SspH family
HCBLAFCG_03640 9.7e-55 yfjF S UPF0060 membrane protein
HCBLAFCG_03641 5.1e-88 S Family of unknown function (DUF5381)
HCBLAFCG_03642 1.2e-124 yfjC
HCBLAFCG_03643 6.9e-170 yfjB
HCBLAFCG_03644 1.1e-44 yfjA S Belongs to the WXG100 family
HCBLAFCG_03645 1.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HCBLAFCG_03646 6e-140 glvR K Helix-turn-helix domain, rpiR family
HCBLAFCG_03647 1.2e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCBLAFCG_03648 2e-308 yfiB3 V ABC transporter
HCBLAFCG_03649 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCBLAFCG_03650 6.4e-64 mhqP S DoxX
HCBLAFCG_03651 2.8e-162 yfiE 1.13.11.2 S glyoxalase
HCBLAFCG_03653 7.5e-211 yxjM T Histidine kinase
HCBLAFCG_03654 5.4e-113 KT LuxR family transcriptional regulator
HCBLAFCG_03655 1.4e-170 V ABC transporter, ATP-binding protein
HCBLAFCG_03656 1.6e-208 V ABC-2 family transporter protein
HCBLAFCG_03657 5.4e-201 V COG0842 ABC-type multidrug transport system, permease component
HCBLAFCG_03658 8.3e-99 padR K transcriptional
HCBLAFCG_03659 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HCBLAFCG_03660 1.3e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HCBLAFCG_03661 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
HCBLAFCG_03662 5.9e-283 yfiU EGP Major facilitator Superfamily
HCBLAFCG_03663 4.9e-79 yfiV K transcriptional
HCBLAFCG_03664 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCBLAFCG_03665 8.2e-174 yfiY P ABC transporter substrate-binding protein
HCBLAFCG_03666 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_03667 8.9e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_03668 8.7e-167 yfhB 5.3.3.17 S PhzF family
HCBLAFCG_03669 3.9e-107 yfhC C nitroreductase
HCBLAFCG_03670 2.1e-25 yfhD S YfhD-like protein
HCBLAFCG_03672 1.2e-171 yfhF S nucleoside-diphosphate sugar epimerase
HCBLAFCG_03673 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HCBLAFCG_03674 3.7e-51 yfhH S Protein of unknown function (DUF1811)
HCBLAFCG_03675 1.1e-209 yfhI EGP Major facilitator Superfamily
HCBLAFCG_03676 6.2e-20 sspK S reproduction
HCBLAFCG_03677 1.3e-44 yfhJ S WVELL protein
HCBLAFCG_03678 2.4e-87 batE T Bacterial SH3 domain homologues
HCBLAFCG_03679 3.9e-50 yfhL S SdpI/YhfL protein family
HCBLAFCG_03680 8.2e-170 yfhM S Alpha beta hydrolase
HCBLAFCG_03681 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCBLAFCG_03682 0.0 yfhO S Bacterial membrane protein YfhO
HCBLAFCG_03683 5.5e-186 yfhP S membrane-bound metal-dependent
HCBLAFCG_03684 3.3e-210 mutY L A G-specific
HCBLAFCG_03685 6.9e-36 yfhS
HCBLAFCG_03686 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_03687 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HCBLAFCG_03688 4.9e-48 ygaB S YgaB-like protein
HCBLAFCG_03689 1.3e-104 ygaC J Belongs to the UPF0374 family
HCBLAFCG_03690 1.8e-301 ygaD V ABC transporter
HCBLAFCG_03691 3.3e-179 ygaE S Membrane
HCBLAFCG_03692 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HCBLAFCG_03693 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
HCBLAFCG_03694 4e-80 perR P Belongs to the Fur family
HCBLAFCG_03695 9.5e-56 ygzB S UPF0295 protein
HCBLAFCG_03696 6.7e-167 ygxA S Nucleotidyltransferase-like
HCBLAFCG_03699 6.1e-157 ydhU P Catalase
HCBLAFCG_03700 8.4e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HCBLAFCG_03701 6.2e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HCBLAFCG_03702 3.9e-170 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HCBLAFCG_03703 1.5e-132 ydhQ K UTRA
HCBLAFCG_03704 3.1e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCBLAFCG_03705 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBLAFCG_03706 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HCBLAFCG_03707 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HCBLAFCG_03708 4.6e-200 pbuE EGP Major facilitator Superfamily
HCBLAFCG_03709 1.7e-99 ydhK M Protein of unknown function (DUF1541)
HCBLAFCG_03710 3.9e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCBLAFCG_03711 4.1e-86 K Acetyltransferase (GNAT) domain
HCBLAFCG_03713 3.3e-67 frataxin S Domain of unknown function (DU1801)
HCBLAFCG_03714 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HCBLAFCG_03715 4.8e-123
HCBLAFCG_03716 1e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HCBLAFCG_03717 6.3e-243 ydhD M Glycosyl hydrolase
HCBLAFCG_03718 6.5e-122 ydhC K FCD
HCBLAFCG_03719 1.6e-121 ydhB S membrane transporter protein
HCBLAFCG_03720 1.6e-208 tcaB EGP Major facilitator Superfamily
HCBLAFCG_03721 7.1e-69 ydgJ K Winged helix DNA-binding domain
HCBLAFCG_03722 8.8e-113 drgA C nitroreductase
HCBLAFCG_03723 0.0 ydgH S drug exporters of the RND superfamily
HCBLAFCG_03724 1.5e-78 K helix_turn_helix multiple antibiotic resistance protein
HCBLAFCG_03725 1.1e-89 dinB S DinB family
HCBLAFCG_03726 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HCBLAFCG_03727 5.2e-298 expZ S ABC transporter
HCBLAFCG_03728 2e-104 G Xylose isomerase-like TIM barrel
HCBLAFCG_03729 3.5e-191 csbC EGP Major facilitator Superfamily
HCBLAFCG_03730 2e-119 purR K helix_turn _helix lactose operon repressor
HCBLAFCG_03731 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HCBLAFCG_03732 7.2e-83 yycN 2.3.1.128 K Acetyltransferase
HCBLAFCG_03733 1.6e-52 S DoxX-like family
HCBLAFCG_03734 6.7e-94 K Bacterial regulatory proteins, tetR family
HCBLAFCG_03735 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HCBLAFCG_03736 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HCBLAFCG_03737 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
HCBLAFCG_03738 2.1e-106 ydfS S Protein of unknown function (DUF421)
HCBLAFCG_03740 5.4e-116 ydfR S Protein of unknown function (DUF421)
HCBLAFCG_03742 4.8e-29
HCBLAFCG_03743 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HCBLAFCG_03744 7.7e-55 traF CO Thioredoxin
HCBLAFCG_03745 8.8e-63 mhqP S DoxX
HCBLAFCG_03746 1.2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HCBLAFCG_03747 1e-108 ydfN C nitroreductase
HCBLAFCG_03748 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCBLAFCG_03749 6e-146 K Bacterial transcription activator, effector binding domain
HCBLAFCG_03750 8.5e-117 S Protein of unknown function (DUF554)
HCBLAFCG_03751 3.1e-175 S Alpha/beta hydrolase family
HCBLAFCG_03752 0.0 ydfJ S drug exporters of the RND superfamily
HCBLAFCG_03753 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCBLAFCG_03754 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
HCBLAFCG_03756 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HCBLAFCG_03757 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HCBLAFCG_03758 2.1e-114 ydfE S Flavin reductase like domain
HCBLAFCG_03759 3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCBLAFCG_03760 7.2e-156 ydfC EG EamA-like transporter family
HCBLAFCG_03761 3.4e-146 ydfB J GNAT acetyltransferase
HCBLAFCG_03762 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HCBLAFCG_03763 8.2e-57 arsR K transcriptional
HCBLAFCG_03764 2.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HCBLAFCG_03765 5.7e-55 K HxlR-like helix-turn-helix
HCBLAFCG_03766 1.8e-104 ydeN S Serine hydrolase
HCBLAFCG_03767 1.3e-72 maoC I N-terminal half of MaoC dehydratase
HCBLAFCG_03768 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCBLAFCG_03769 2e-152 ydeK EG -transporter
HCBLAFCG_03770 3.4e-84 K Transcriptional regulator C-terminal region
HCBLAFCG_03771 1.8e-14 ptsH G PTS HPr component phosphorylation site
HCBLAFCG_03772 6.7e-32 S SNARE associated Golgi protein
HCBLAFCG_03773 1.3e-106
HCBLAFCG_03774 9.2e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HCBLAFCG_03775 1.5e-43 ydeH
HCBLAFCG_03776 3.5e-217 ydeG EGP Major facilitator superfamily
HCBLAFCG_03777 6.2e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCBLAFCG_03778 6.9e-164 ydeE K AraC family transcriptional regulator
HCBLAFCG_03779 2.4e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HCBLAFCG_03780 5.8e-163 rhaS5 K AraC-like ligand binding domain
HCBLAFCG_03781 1.8e-140 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HCBLAFCG_03782 2.3e-78 carD K Transcription factor
HCBLAFCG_03783 8.7e-30 cspL K Cold shock
HCBLAFCG_03784 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HCBLAFCG_03788 1.2e-39
HCBLAFCG_03789 5.6e-34 K Helix-turn-helix XRE-family like proteins
HCBLAFCG_03790 2.7e-13
HCBLAFCG_03791 4.7e-140 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HCBLAFCG_03792 1.4e-42
HCBLAFCG_03793 1.3e-75 rimJ2 J Acetyltransferase (GNAT) domain
HCBLAFCG_03801 8.9e-83 ydcK S Belongs to the SprT family
HCBLAFCG_03802 0.0 yhgF K COG2183 Transcriptional accessory protein
HCBLAFCG_03803 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HCBLAFCG_03804 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCBLAFCG_03805 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HCBLAFCG_03806 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HCBLAFCG_03807 9.3e-189 rsbU 3.1.3.3 KT phosphatase
HCBLAFCG_03808 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HCBLAFCG_03809 5.2e-57 rsbS T antagonist
HCBLAFCG_03810 3.7e-143 rsbR T Positive regulator of sigma-B
HCBLAFCG_03811 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HCBLAFCG_03812 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HCBLAFCG_03813 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCBLAFCG_03814 5.5e-182 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HCBLAFCG_03815 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCBLAFCG_03816 2.2e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HCBLAFCG_03817 1.1e-259 ydbT S Membrane
HCBLAFCG_03818 1.8e-81 ydbS S Bacterial PH domain
HCBLAFCG_03819 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCBLAFCG_03820 6.7e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCBLAFCG_03821 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HCBLAFCG_03822 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HCBLAFCG_03823 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCBLAFCG_03824 2.2e-07 S Fur-regulated basic protein A
HCBLAFCG_03825 1.1e-18 S Fur-regulated basic protein B
HCBLAFCG_03826 8.3e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HCBLAFCG_03827 2.7e-52 ydbL
HCBLAFCG_03828 7.9e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HCBLAFCG_03829 4e-170 ydbJ V ABC transporter, ATP-binding protein
HCBLAFCG_03830 4.4e-181 ydbI S AI-2E family transporter
HCBLAFCG_03831 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCBLAFCG_03832 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HCBLAFCG_03833 1.1e-295 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HCBLAFCG_03834 2.3e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HCBLAFCG_03835 7.9e-154 ydbD P Catalase
HCBLAFCG_03836 2e-61 ydbC S Domain of unknown function (DUF4937
HCBLAFCG_03837 1.2e-55 ydbB G Cupin domain
HCBLAFCG_03839 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HCBLAFCG_03840 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HCBLAFCG_03842 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HCBLAFCG_03843 2.1e-39
HCBLAFCG_03844 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCBLAFCG_03845 5.6e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HCBLAFCG_03846 0.0 ydaO E amino acid
HCBLAFCG_03847 0.0 ydaN S Bacterial cellulose synthase subunit
HCBLAFCG_03848 4.5e-233 ydaM M Glycosyl transferase family group 2
HCBLAFCG_03849 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HCBLAFCG_03850 4.6e-149 ydaK T Diguanylate cyclase, GGDEF domain
HCBLAFCG_03851 2.6e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HCBLAFCG_03852 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCBLAFCG_03853 2.5e-74 lrpC K Transcriptional regulator
HCBLAFCG_03854 2.4e-44 ydzA EGP Major facilitator Superfamily
HCBLAFCG_03855 9.2e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HCBLAFCG_03856 6.8e-77 ydaG 1.4.3.5 S general stress protein
HCBLAFCG_03857 2.1e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HCBLAFCG_03858 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HCBLAFCG_03859 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_03860 9e-99 ydaC Q Methyltransferase domain
HCBLAFCG_03861 6.7e-292 ydaB IQ acyl-CoA ligase
HCBLAFCG_03862 0.0 mtlR K transcriptional regulator, MtlR
HCBLAFCG_03863 9.2e-172 ydhF S Oxidoreductase
HCBLAFCG_03864 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HCBLAFCG_03865 3.1e-49 yczJ S biosynthesis
HCBLAFCG_03867 7.1e-118 ycsK E anatomical structure formation involved in morphogenesis
HCBLAFCG_03868 6e-132 kipR K Transcriptional regulator
HCBLAFCG_03869 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HCBLAFCG_03870 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HCBLAFCG_03871 3.7e-148 ycsI S Belongs to the D-glutamate cyclase family
HCBLAFCG_03872 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HCBLAFCG_03873 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
HCBLAFCG_03874 2.3e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HCBLAFCG_03876 1.6e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HCBLAFCG_03877 6.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HCBLAFCG_03878 2.2e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HCBLAFCG_03880 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HCBLAFCG_03881 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HCBLAFCG_03882 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HCBLAFCG_03883 9.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HCBLAFCG_03884 3.4e-53
HCBLAFCG_03885 1.8e-104 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HCBLAFCG_03886 3.9e-306 ycnJ P protein, homolog of Cu resistance protein CopC
HCBLAFCG_03887 2.3e-97 ycnI S protein conserved in bacteria
HCBLAFCG_03888 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCBLAFCG_03889 6.1e-149 glcU U Glucose uptake
HCBLAFCG_03890 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCBLAFCG_03891 4.8e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCBLAFCG_03892 1.1e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCBLAFCG_03893 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HCBLAFCG_03894 4.7e-45 ycnE S Monooxygenase
HCBLAFCG_03895 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HCBLAFCG_03896 5.5e-153 ycnC K Transcriptional regulator
HCBLAFCG_03897 1.4e-251 ycnB EGP Major facilitator Superfamily
HCBLAFCG_03898 1.1e-170 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HCBLAFCG_03899 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HCBLAFCG_03900 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_03901 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_03902 1.1e-240 lysC 2.7.2.4 E Belongs to the aspartokinase family
HCBLAFCG_03906 2e-70 S aspartate phosphatase
HCBLAFCG_03907 4.9e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HCBLAFCG_03908 1e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_03909 9e-201 yclI V ABC transporter (permease) YclI
HCBLAFCG_03910 5.6e-121 yclH P ABC transporter
HCBLAFCG_03911 1e-196 gerKB F Spore germination protein
HCBLAFCG_03912 8e-227 gerKC S spore germination
HCBLAFCG_03913 1.9e-276 gerKA EG Spore germination protein
HCBLAFCG_03915 5.9e-292 yclG M Pectate lyase superfamily protein
HCBLAFCG_03916 7.3e-267 dtpT E amino acid peptide transporter
HCBLAFCG_03917 1.9e-158 yclE 3.4.11.5 S Alpha beta hydrolase
HCBLAFCG_03918 2.3e-81 yclD
HCBLAFCG_03919 4e-39 bsdD 4.1.1.61 S response to toxic substance
HCBLAFCG_03920 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HCBLAFCG_03921 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HCBLAFCG_03922 4.9e-162 bsdA K LysR substrate binding domain
HCBLAFCG_03923 1.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HCBLAFCG_03924 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HCBLAFCG_03925 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCBLAFCG_03926 1.7e-114 yczE S membrane
HCBLAFCG_03927 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HCBLAFCG_03928 5.6e-250 ycxD K GntR family transcriptional regulator
HCBLAFCG_03929 6.4e-160 ycxC EG EamA-like transporter family
HCBLAFCG_03930 2.3e-88 S YcxB-like protein
HCBLAFCG_03931 6.1e-227 EGP Major Facilitator Superfamily
HCBLAFCG_03932 6.4e-139 srfAD Q thioesterase
HCBLAFCG_03933 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HCBLAFCG_03934 1.4e-245 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBLAFCG_03935 1.3e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HCBLAFCG_03937 1e-160 ybaS 1.1.1.58 S Na -dependent transporter
HCBLAFCG_03938 5.6e-138 ybbA S Putative esterase
HCBLAFCG_03939 8.7e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_03940 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBLAFCG_03941 3e-165 feuA P Iron-uptake system-binding protein
HCBLAFCG_03942 2.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HCBLAFCG_03943 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
HCBLAFCG_03944 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HCBLAFCG_03945 4.1e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HCBLAFCG_03946 3.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCBLAFCG_03947 1.4e-150 ybbH K transcriptional
HCBLAFCG_03948 3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCBLAFCG_03949 4.1e-86 ybbJ J acetyltransferase
HCBLAFCG_03950 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HCBLAFCG_03956 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HCBLAFCG_03957 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HCBLAFCG_03958 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCBLAFCG_03959 5.7e-224 ybbR S protein conserved in bacteria
HCBLAFCG_03960 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCBLAFCG_03961 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCBLAFCG_03962 6e-171 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HCBLAFCG_03963 9.8e-120 adaA 3.2.2.21 K Transcriptional regulator
HCBLAFCG_03964 3.3e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCBLAFCG_03965 8.8e-276 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HCBLAFCG_03966 0.0 ybcC S Belongs to the UPF0753 family
HCBLAFCG_03967 4.7e-91 can 4.2.1.1 P carbonic anhydrase
HCBLAFCG_03969 1.9e-46
HCBLAFCG_03970 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HCBLAFCG_03971 5.1e-50 ybzH K Helix-turn-helix domain
HCBLAFCG_03972 4.5e-203 ybcL EGP Major facilitator Superfamily
HCBLAFCG_03973 1.2e-55
HCBLAFCG_03974 5.3e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HCBLAFCG_03975 4.2e-121 T Transcriptional regulatory protein, C terminal
HCBLAFCG_03976 1.8e-168 T His Kinase A (phospho-acceptor) domain
HCBLAFCG_03978 3.9e-139 KLT Protein tyrosine kinase
HCBLAFCG_03979 1.7e-151 ybdN
HCBLAFCG_03980 1e-215 ybdO S Domain of unknown function (DUF4885)
HCBLAFCG_03981 2.6e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HCBLAFCG_03982 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HCBLAFCG_03983 4.9e-30 ybxH S Family of unknown function (DUF5370)
HCBLAFCG_03984 5.2e-150 ybxI 3.5.2.6 V beta-lactamase
HCBLAFCG_03985 1.7e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HCBLAFCG_03986 4.9e-41 ybyB
HCBLAFCG_03987 1.8e-290 ybeC E amino acid
HCBLAFCG_03988 3.4e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCBLAFCG_03989 7.3e-258 glpT G -transporter
HCBLAFCG_03990 1.6e-33 S Protein of unknown function (DUF2651)
HCBLAFCG_03991 1.4e-170 ybfA 3.4.15.5 K FR47-like protein
HCBLAFCG_03992 3.8e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
HCBLAFCG_03993 6.3e-160 ybfH EG EamA-like transporter family
HCBLAFCG_03994 2.3e-145 msmR K AraC-like ligand binding domain
HCBLAFCG_03995 5.2e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HCBLAFCG_03996 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HCBLAFCG_03998 2.4e-164 S Alpha/beta hydrolase family
HCBLAFCG_03999 2.7e-94 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCBLAFCG_04000 2.7e-85 ybfM S SNARE associated Golgi protein
HCBLAFCG_04001 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HCBLAFCG_04002 4.6e-45 ybfN
HCBLAFCG_04003 3.6e-249 S Erythromycin esterase
HCBLAFCG_04004 3.9e-192 yceA S Belongs to the UPF0176 family
HCBLAFCG_04005 1.1e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCBLAFCG_04006 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCBLAFCG_04007 2.4e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCBLAFCG_04008 4.9e-128 K UTRA
HCBLAFCG_04010 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HCBLAFCG_04011 1.8e-259 mmuP E amino acid
HCBLAFCG_04012 3.3e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HCBLAFCG_04014 4.3e-256 agcS E Sodium alanine symporter
HCBLAFCG_04015 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
HCBLAFCG_04016 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
HCBLAFCG_04017 9e-170 glnL T Regulator
HCBLAFCG_04018 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HCBLAFCG_04019 2.6e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCBLAFCG_04020 1.6e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HCBLAFCG_04021 6.5e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HCBLAFCG_04022 2.1e-123 ycbG K FCD
HCBLAFCG_04023 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
HCBLAFCG_04024 6.3e-176 ycbJ S Macrolide 2'-phosphotransferase
HCBLAFCG_04025 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HCBLAFCG_04026 5.4e-167 eamA1 EG spore germination
HCBLAFCG_04027 8.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCBLAFCG_04028 4.2e-167 T PhoQ Sensor
HCBLAFCG_04029 4.1e-167 ycbN V ABC transporter, ATP-binding protein
HCBLAFCG_04030 5.1e-114 S ABC-2 family transporter protein
HCBLAFCG_04031 4.1e-52 ycbP S Protein of unknown function (DUF2512)
HCBLAFCG_04032 1.3e-78 sleB 3.5.1.28 M Cell wall
HCBLAFCG_04033 4.7e-134 ycbR T vWA found in TerF C terminus
HCBLAFCG_04034 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HCBLAFCG_04035 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HCBLAFCG_04036 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HCBLAFCG_04037 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HCBLAFCG_04038 1e-204 ycbU E Selenocysteine lyase
HCBLAFCG_04039 5.8e-229 lmrB EGP the major facilitator superfamily
HCBLAFCG_04040 5.9e-100 yxaF K Transcriptional regulator
HCBLAFCG_04041 1e-199 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HCBLAFCG_04042 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HCBLAFCG_04043 2.1e-56 S RDD family
HCBLAFCG_04044 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
HCBLAFCG_04045 1.6e-158 2.7.13.3 T GHKL domain
HCBLAFCG_04046 1.2e-126 lytR_2 T LytTr DNA-binding domain
HCBLAFCG_04047 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HCBLAFCG_04048 1.8e-199 natB CP ABC-2 family transporter protein
HCBLAFCG_04049 4.3e-79 yccK C Aldo keto reductase
HCBLAFCG_04050 5.8e-137 ycdA S Domain of unknown function (DUF5105)
HCBLAFCG_04051 4.7e-271 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HCBLAFCG_04052 2.2e-258 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HCBLAFCG_04053 1.1e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
HCBLAFCG_04054 1.2e-173 S response regulator aspartate phosphatase
HCBLAFCG_04055 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HCBLAFCG_04056 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HCBLAFCG_04057 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
HCBLAFCG_04058 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HCBLAFCG_04059 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HCBLAFCG_04060 6.6e-187 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCBLAFCG_04061 2.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HCBLAFCG_04062 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HCBLAFCG_04063 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HCBLAFCG_04064 1.4e-136 terC P Protein of unknown function (DUF475)
HCBLAFCG_04065 0.0 yceG S Putative component of 'biosynthetic module'
HCBLAFCG_04066 2e-192 yceH P Belongs to the TelA family
HCBLAFCG_04067 1.9e-217 naiP P Uncharacterised MFS-type transporter YbfB
HCBLAFCG_04068 5.7e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
HCBLAFCG_04069 5.1e-229 proV 3.6.3.32 E glycine betaine
HCBLAFCG_04070 1.3e-127 opuAB P glycine betaine
HCBLAFCG_04071 1.5e-163 opuAC E glycine betaine
HCBLAFCG_04072 1.4e-217 amhX S amidohydrolase
HCBLAFCG_04073 8.7e-257 ycgA S Membrane
HCBLAFCG_04074 4.1e-81 ycgB
HCBLAFCG_04075 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HCBLAFCG_04076 7.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HCBLAFCG_04077 5.2e-290 lctP C L-lactate permease
HCBLAFCG_04078 3.6e-261 mdr EGP Major facilitator Superfamily
HCBLAFCG_04079 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HCBLAFCG_04080 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HCBLAFCG_04081 9.2e-149 yqcI S YqcI/YcgG family
HCBLAFCG_04082 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HCBLAFCG_04083 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HCBLAFCG_04084 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCBLAFCG_04085 6.2e-108 tmrB S AAA domain
HCBLAFCG_04087 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HCBLAFCG_04088 2.6e-143 yafE Q ubiE/COQ5 methyltransferase family
HCBLAFCG_04089 1e-176 oxyR3 K LysR substrate binding domain
HCBLAFCG_04090 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HCBLAFCG_04091 1.6e-143 ycgL S Predicted nucleotidyltransferase
HCBLAFCG_04092 5.1e-170 ycgM E Proline dehydrogenase
HCBLAFCG_04093 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HCBLAFCG_04094 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCBLAFCG_04095 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HCBLAFCG_04096 1.4e-145 ycgQ S membrane
HCBLAFCG_04097 1.2e-139 ycgR S permeases
HCBLAFCG_04098 2.1e-157 I alpha/beta hydrolase fold
HCBLAFCG_04099 4.2e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HCBLAFCG_04100 5.8e-277 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HCBLAFCG_04101 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HCBLAFCG_04102 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HCBLAFCG_04103 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCBLAFCG_04104 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HCBLAFCG_04105 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
HCBLAFCG_04106 7.9e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HCBLAFCG_04107 8.8e-107 yciB M ErfK YbiS YcfS YnhG
HCBLAFCG_04108 5.4e-228 yciC S GTPases (G3E family)
HCBLAFCG_04109 1.6e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
HCBLAFCG_04110 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HCBLAFCG_04112 7.8e-52 yckD S Protein of unknown function (DUF2680)
HCBLAFCG_04113 1.6e-38 K MarR family
HCBLAFCG_04114 9.3e-24
HCBLAFCG_04115 7.8e-121 S AAA domain
HCBLAFCG_04116 2.8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCBLAFCG_04117 6.5e-69 nin S Competence protein J (ComJ)
HCBLAFCG_04118 3e-70 nucA M Deoxyribonuclease NucA/NucB
HCBLAFCG_04119 1.5e-186 tlpC 2.7.13.3 NT chemotaxis protein
HCBLAFCG_04120 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HCBLAFCG_04121 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HCBLAFCG_04122 1.3e-63 hxlR K transcriptional
HCBLAFCG_04123 2.2e-182 I Pfam Lipase (class 3)
HCBLAFCG_04124 4.1e-41
HCBLAFCG_04126 2.1e-21 K Cro/C1-type HTH DNA-binding domain
HCBLAFCG_04131 4e-07
HCBLAFCG_04133 7.8e-54 L Recombinase
HCBLAFCG_04134 5.6e-153 pbuX F xanthine
HCBLAFCG_04135 4.4e-208 bcsA Q Naringenin-chalcone synthase
HCBLAFCG_04136 5.1e-87 ypbQ S protein conserved in bacteria
HCBLAFCG_04137 0.0 ypbR S Dynamin family
HCBLAFCG_04138 1e-38 ypbS S Protein of unknown function (DUF2533)
HCBLAFCG_04139 2e-07
HCBLAFCG_04140 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HCBLAFCG_04142 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
HCBLAFCG_04143 1.1e-121 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HCBLAFCG_04144 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HCBLAFCG_04145 2.6e-27 ypeQ S Zinc-finger
HCBLAFCG_04146 8.1e-31 S Protein of unknown function (DUF2564)
HCBLAFCG_04147 3.8e-16 degR
HCBLAFCG_04148 1e-30 cspD K Cold-shock protein
HCBLAFCG_04149 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HCBLAFCG_04150 3.6e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HCBLAFCG_04151 9.8e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HCBLAFCG_04152 1.5e-104 ypgQ S phosphohydrolase
HCBLAFCG_04153 9.8e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
HCBLAFCG_04155 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HCBLAFCG_04156 1.7e-75 yphP S Belongs to the UPF0403 family
HCBLAFCG_04157 8.5e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HCBLAFCG_04158 7.8e-114 ypjP S YpjP-like protein
HCBLAFCG_04159 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HCBLAFCG_04160 2.4e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCBLAFCG_04161 5.3e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HCBLAFCG_04162 2.7e-109 hlyIII S protein, Hemolysin III
HCBLAFCG_04163 1.5e-183 pspF K Transcriptional regulator
HCBLAFCG_04164 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HCBLAFCG_04165 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HCBLAFCG_04166 7.1e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HCBLAFCG_04167 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HCBLAFCG_04168 1.1e-98 ypmS S protein conserved in bacteria
HCBLAFCG_04169 1.6e-28 ypmT S Uncharacterized ympT
HCBLAFCG_04170 7.6e-223 mepA V MATE efflux family protein
HCBLAFCG_04171 1.6e-70 ypoP K transcriptional
HCBLAFCG_04172 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCBLAFCG_04173 6.4e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HCBLAFCG_04174 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HCBLAFCG_04175 1.7e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HCBLAFCG_04176 2.5e-183 cgeB S Spore maturation protein
HCBLAFCG_04177 1.5e-65 cgeA
HCBLAFCG_04178 3.5e-38 cgeC
HCBLAFCG_04179 6.8e-253 cgeD M maturation of the outermost layer of the spore
HCBLAFCG_04180 2e-143 yiiD K acetyltransferase
HCBLAFCG_04182 9.9e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCBLAFCG_04183 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HCBLAFCG_04184 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HCBLAFCG_04185 4.6e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
HCBLAFCG_04186 5.7e-152 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HCBLAFCG_04187 1.1e-277 kamA 5.4.3.2 E lysine 2,3-aminomutase
HCBLAFCG_04188 2.9e-47 yokU S YokU-like protein, putative antitoxin
HCBLAFCG_04189 6.9e-36 yozE S Belongs to the UPF0346 family
HCBLAFCG_04190 6e-123 yodN
HCBLAFCG_04192 1.1e-23 yozD S YozD-like protein
HCBLAFCG_04193 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
HCBLAFCG_04194 3.6e-54 yodL S YodL-like
HCBLAFCG_04195 5.3e-09
HCBLAFCG_04196 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HCBLAFCG_04197 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HCBLAFCG_04198 5.2e-24 yodI
HCBLAFCG_04199 4.3e-42 yodH Q Methyltransferase
HCBLAFCG_04200 1e-70 yodH Q Methyltransferase
HCBLAFCG_04201 3.8e-249 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HCBLAFCG_04202 5.1e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCBLAFCG_04203 6.2e-28 S Protein of unknown function (DUF3311)
HCBLAFCG_04204 7.1e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
HCBLAFCG_04205 3.8e-113 mhqD S Carboxylesterase
HCBLAFCG_04206 1.4e-107 yodC C nitroreductase
HCBLAFCG_04207 4.4e-55 yodB K transcriptional
HCBLAFCG_04208 8e-64 yodA S tautomerase
HCBLAFCG_04209 7e-61 gntP EG COG2610 H gluconate symporter and related permeases
HCBLAFCG_04210 3.5e-127 gntP EG COG2610 H gluconate symporter and related permeases
HCBLAFCG_04211 2.6e-09
HCBLAFCG_04212 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
HCBLAFCG_04213 8.6e-162 rarD S -transporter
HCBLAFCG_04214 1.5e-43
HCBLAFCG_04215 6.3e-60 yojF S Protein of unknown function (DUF1806)
HCBLAFCG_04216 2.1e-125 yojG S deacetylase
HCBLAFCG_04217 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HCBLAFCG_04218 1.6e-244 norM V Multidrug efflux pump
HCBLAFCG_04220 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCBLAFCG_04221 3.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HCBLAFCG_04222 7.9e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HCBLAFCG_04223 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HCBLAFCG_04224 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
HCBLAFCG_04225 0.0 yojO P Von Willebrand factor
HCBLAFCG_04226 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HCBLAFCG_04227 9.4e-191 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HCBLAFCG_04228 5.6e-167 yocS S -transporter
HCBLAFCG_04229 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HCBLAFCG_04230 8e-162 sodA 1.15.1.1 P Superoxide dismutase
HCBLAFCG_04231 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HCBLAFCG_04232 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HCBLAFCG_04233 2.7e-31 yozC
HCBLAFCG_04234 4.2e-56 yozO S Bacterial PH domain
HCBLAFCG_04235 1.9e-36 yocN
HCBLAFCG_04236 1.1e-40 yozN
HCBLAFCG_04237 6.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HCBLAFCG_04238 8.3e-29
HCBLAFCG_04239 8.4e-54 yocL
HCBLAFCG_04240 7.4e-83 dksA T general stress protein
HCBLAFCG_04241 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCBLAFCG_04242 0.0 recQ 3.6.4.12 L DNA helicase
HCBLAFCG_04243 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HCBLAFCG_04244 2.2e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCBLAFCG_04245 3.2e-198 desK 2.7.13.3 T Histidine kinase
HCBLAFCG_04246 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HCBLAFCG_04247 1.8e-184 yocD 3.4.17.13 V peptidase S66
HCBLAFCG_04248 3.4e-91 yocC
HCBLAFCG_04249 5.1e-142
HCBLAFCG_04250 1.5e-92 yozB S membrane
HCBLAFCG_04251 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HCBLAFCG_04252 1e-51 czrA K transcriptional
HCBLAFCG_04253 7.2e-95 yobW
HCBLAFCG_04254 6.4e-176 yobV K WYL domain
HCBLAFCG_04255 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
HCBLAFCG_04256 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HCBLAFCG_04257 2.8e-97 yobS K Transcriptional regulator
HCBLAFCG_04258 7.7e-140 yobR 2.3.1.1 J FR47-like protein
HCBLAFCG_04259 7.9e-134 yobQ K helix_turn_helix, arabinose operon control protein
HCBLAFCG_04260 3.8e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HCBLAFCG_04261 2.9e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HCBLAFCG_04262 4.1e-101 yokH G SMI1 / KNR4 family
HCBLAFCG_04263 4.5e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HCBLAFCG_04264 7.3e-28 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCBLAFCG_04265 6.9e-19
HCBLAFCG_04267 1.8e-95 S aspartate phosphatase
HCBLAFCG_04268 1.3e-63 yoaQ S Evidence 4 Homologs of previously reported genes of
HCBLAFCG_04270 2.5e-116
HCBLAFCG_04272 2.8e-77 mepB S MepB protein
HCBLAFCG_04274 2.6e-55 K Helix-turn-helix
HCBLAFCG_04275 8.8e-37 S TM2 domain
HCBLAFCG_04276 6.9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HCBLAFCG_04277 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HCBLAFCG_04280 4.5e-166 bla 3.5.2.6 V beta-lactamase
HCBLAFCG_04281 2.1e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HCBLAFCG_04282 6.3e-78 yoaW
HCBLAFCG_04283 3.7e-157 yijE EG EamA-like transporter family
HCBLAFCG_04284 3.6e-157 yoaU K LysR substrate binding domain
HCBLAFCG_04285 4.8e-148 yoaT S Protein of unknown function (DUF817)
HCBLAFCG_04286 4.4e-30 yozG K Transcriptional regulator
HCBLAFCG_04287 7.3e-75 yoaS S Protein of unknown function (DUF2975)
HCBLAFCG_04288 7.1e-172 yoaR V vancomycin resistance protein
HCBLAFCG_04289 8.9e-84
HCBLAFCG_04292 1.3e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
HCBLAFCG_04295 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
HCBLAFCG_04296 4.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HCBLAFCG_04297 2.3e-111 yoaK S Membrane
HCBLAFCG_04298 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HCBLAFCG_04299 3.7e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HCBLAFCG_04300 2.3e-184 mcpU NT methyl-accepting chemotaxis protein
HCBLAFCG_04301 1.5e-38 S Protein of unknown function (DUF4025)
HCBLAFCG_04302 7e-14
HCBLAFCG_04303 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
HCBLAFCG_04304 1.1e-33 yoaF
HCBLAFCG_04305 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCBLAFCG_04306 3.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBLAFCG_04307 6.5e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HCBLAFCG_04308 4e-234 yoaB EGP Major facilitator Superfamily
HCBLAFCG_04309 3.9e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
HCBLAFCG_04310 5.7e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
HCBLAFCG_04311 9.8e-95 V ABC-2 family transporter protein
HCBLAFCG_04312 6.9e-128 V ABC-2 family transporter protein
HCBLAFCG_04313 9.2e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HCBLAFCG_04314 4.2e-133 yoxB
HCBLAFCG_04315 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
HCBLAFCG_04316 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBLAFCG_04317 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HCBLAFCG_04318 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCBLAFCG_04319 6e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCBLAFCG_04320 7.8e-155 gltC K Transcriptional regulator
HCBLAFCG_04321 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HCBLAFCG_04322 3.8e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HCBLAFCG_04323 6.7e-18 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HCBLAFCG_04324 8.3e-151 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HCBLAFCG_04325 8.2e-154 gltR1 K Transcriptional regulator
HCBLAFCG_04326 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HCBLAFCG_04327 3e-34 yoeD G Helix-turn-helix domain
HCBLAFCG_04328 2.2e-96 L Integrase
HCBLAFCG_04330 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HCBLAFCG_04331 3e-246 yoeA V MATE efflux family protein
HCBLAFCG_04332 4e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
HCBLAFCG_04333 2.9e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)