ORF_ID e_value Gene_name EC_number CAZy COGs Description
DKLCKOFC_00001 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DKLCKOFC_00004 3e-270 recD2 3.6.4.12 L PIF1-like helicase
DKLCKOFC_00005 9e-161 supH S Sucrose-6F-phosphate phosphohydrolase
DKLCKOFC_00006 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
DKLCKOFC_00007 1.2e-24 KT Transcriptional regulatory protein, C terminal
DKLCKOFC_00008 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
DKLCKOFC_00009 3.5e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DKLCKOFC_00010 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
DKLCKOFC_00011 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
DKLCKOFC_00012 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
DKLCKOFC_00013 3e-184 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DKLCKOFC_00014 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DKLCKOFC_00015 3.9e-36 rpmE J Binds the 23S rRNA
DKLCKOFC_00017 2.1e-196 K helix_turn_helix, arabinose operon control protein
DKLCKOFC_00018 2.6e-163 glcU G Sugar transport protein
DKLCKOFC_00019 1.3e-177 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
DKLCKOFC_00020 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
DKLCKOFC_00021 1.5e-108
DKLCKOFC_00022 8.3e-170 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
DKLCKOFC_00023 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
DKLCKOFC_00024 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
DKLCKOFC_00025 4.2e-164 EG EamA-like transporter family
DKLCKOFC_00027 1.1e-140 V FtsX-like permease family
DKLCKOFC_00028 3.4e-147 S Sulfite exporter TauE/SafE
DKLCKOFC_00030 1.9e-26 L Transposase
DKLCKOFC_00031 1.7e-215 MA20_36090 S Psort location Cytoplasmic, score 8.87
DKLCKOFC_00032 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
DKLCKOFC_00033 9.3e-36 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
DKLCKOFC_00034 6.8e-73 EGP Major facilitator superfamily
DKLCKOFC_00035 4e-10 K Winged helix DNA-binding domain
DKLCKOFC_00036 3.7e-179 glkA 2.7.1.2 G ROK family
DKLCKOFC_00037 7.8e-299 S ATPases associated with a variety of cellular activities
DKLCKOFC_00038 1.2e-55 EGP Major facilitator Superfamily
DKLCKOFC_00039 1.1e-158 I alpha/beta hydrolase fold
DKLCKOFC_00040 1.1e-110 S Pyridoxamine 5'-phosphate oxidase
DKLCKOFC_00042 1.3e-55 S DUF218 domain
DKLCKOFC_00043 6.3e-17 S Protein of unknown function (DUF979)
DKLCKOFC_00044 1.7e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DKLCKOFC_00046 1.8e-59
DKLCKOFC_00047 4.6e-35
DKLCKOFC_00048 4.7e-48 M domain, Protein
DKLCKOFC_00049 9.6e-15 M domain, Protein
DKLCKOFC_00050 2.8e-37 S Protein of unknown function (DUF3791)
DKLCKOFC_00051 1.4e-89 S Protein of unknown function (DUF3990)
DKLCKOFC_00052 2e-07
DKLCKOFC_00053 5.6e-67 fic D Fic/DOC family
DKLCKOFC_00054 3.2e-25 fic D Fic/DOC family
DKLCKOFC_00056 1.2e-97 S Domain of unknown function (DUF4825)
DKLCKOFC_00057 2.5e-43 K response regulator
DKLCKOFC_00058 2.1e-45 T response regulator
DKLCKOFC_00059 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
DKLCKOFC_00060 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
DKLCKOFC_00061 7.1e-172 tesB I Thioesterase-like superfamily
DKLCKOFC_00062 1.3e-77 S Protein of unknown function (DUF3180)
DKLCKOFC_00063 2.1e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DKLCKOFC_00064 2.3e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DKLCKOFC_00065 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
DKLCKOFC_00066 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DKLCKOFC_00067 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DKLCKOFC_00068 1.1e-211 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DKLCKOFC_00069 4.5e-261 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
DKLCKOFC_00070 2.5e-308
DKLCKOFC_00071 1.7e-168 natA V ATPases associated with a variety of cellular activities
DKLCKOFC_00072 1.3e-232 epsG M Glycosyl transferase family 21
DKLCKOFC_00073 4.3e-273 S AI-2E family transporter
DKLCKOFC_00074 4.3e-177 3.4.14.13 M Glycosyltransferase like family 2
DKLCKOFC_00075 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
DKLCKOFC_00078 2.6e-68 S Domain of unknown function (DUF4190)
DKLCKOFC_00079 1.2e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DKLCKOFC_00080 1.1e-175 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DKLCKOFC_00082 1.6e-17 S Transcription factor WhiB
DKLCKOFC_00083 8.6e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
DKLCKOFC_00084 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DKLCKOFC_00085 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
DKLCKOFC_00086 2e-182 lacR K Transcriptional regulator, LacI family
DKLCKOFC_00087 5.2e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DKLCKOFC_00088 3.9e-119 K Transcriptional regulatory protein, C terminal
DKLCKOFC_00089 2.2e-95
DKLCKOFC_00090 1.5e-178 V N-Acetylmuramoyl-L-alanine amidase
DKLCKOFC_00091 1.6e-108 ytrE V ABC transporter
DKLCKOFC_00092 6.6e-172
DKLCKOFC_00094 4.7e-220 vex3 V ABC transporter permease
DKLCKOFC_00095 3.2e-212 vex1 V Efflux ABC transporter, permease protein
DKLCKOFC_00096 1.3e-111 vex2 V ABC transporter, ATP-binding protein
DKLCKOFC_00097 9.4e-23 azlD E Branched-chain amino acid transport protein (AzlD)
DKLCKOFC_00098 2.2e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
DKLCKOFC_00099 6.2e-96 ptpA 3.1.3.48 T low molecular weight
DKLCKOFC_00100 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
DKLCKOFC_00101 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DKLCKOFC_00102 8.5e-72 attW O OsmC-like protein
DKLCKOFC_00103 7.8e-191 T Universal stress protein family
DKLCKOFC_00104 1.7e-105 M NlpC/P60 family
DKLCKOFC_00105 9.1e-176 usp 3.5.1.28 CBM50 S CHAP domain
DKLCKOFC_00106 8.5e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DKLCKOFC_00107 2.6e-39
DKLCKOFC_00108 2.3e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DKLCKOFC_00109 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
DKLCKOFC_00110 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DKLCKOFC_00111 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
DKLCKOFC_00112 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DKLCKOFC_00114 1.2e-216 araJ EGP Major facilitator Superfamily
DKLCKOFC_00115 0.0 S Domain of unknown function (DUF4037)
DKLCKOFC_00116 4.3e-112 S Protein of unknown function (DUF4125)
DKLCKOFC_00117 2.1e-129
DKLCKOFC_00118 1.9e-290 pspC KT PspC domain
DKLCKOFC_00119 8.9e-273 tcsS3 KT PspC domain
DKLCKOFC_00120 9.2e-126 degU K helix_turn_helix, Lux Regulon
DKLCKOFC_00121 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DKLCKOFC_00123 6e-143 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
DKLCKOFC_00124 7.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
DKLCKOFC_00125 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DKLCKOFC_00126 1.2e-94
DKLCKOFC_00128 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
DKLCKOFC_00130 3.8e-238 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DKLCKOFC_00131 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
DKLCKOFC_00132 5.1e-212 I Diacylglycerol kinase catalytic domain
DKLCKOFC_00133 1.3e-151 arbG K CAT RNA binding domain
DKLCKOFC_00134 0.0 crr G pts system, glucose-specific IIABC component
DKLCKOFC_00135 4.4e-42 M Spy0128-like isopeptide containing domain
DKLCKOFC_00136 2.7e-43 M Spy0128-like isopeptide containing domain
DKLCKOFC_00137 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
DKLCKOFC_00138 4.4e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKLCKOFC_00139 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
DKLCKOFC_00140 3.8e-204 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DKLCKOFC_00141 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DKLCKOFC_00143 1.2e-106
DKLCKOFC_00144 6.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DKLCKOFC_00145 6.9e-234 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
DKLCKOFC_00146 1.6e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DKLCKOFC_00147 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DKLCKOFC_00148 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DKLCKOFC_00149 2.8e-188 nusA K Participates in both transcription termination and antitermination
DKLCKOFC_00150 1.6e-161
DKLCKOFC_00151 1.1e-145 L Transposase and inactivated derivatives
DKLCKOFC_00153 1.3e-153 E Transglutaminase/protease-like homologues
DKLCKOFC_00154 0.0 gcs2 S A circularly permuted ATPgrasp
DKLCKOFC_00155 3.2e-172 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DKLCKOFC_00156 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
DKLCKOFC_00157 8.1e-64 rplQ J Ribosomal protein L17
DKLCKOFC_00158 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DKLCKOFC_00159 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DKLCKOFC_00160 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DKLCKOFC_00161 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DKLCKOFC_00162 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DKLCKOFC_00163 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DKLCKOFC_00164 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DKLCKOFC_00165 2.7e-63 rplO J binds to the 23S rRNA
DKLCKOFC_00166 1e-24 rpmD J Ribosomal protein L30p/L7e
DKLCKOFC_00167 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DKLCKOFC_00168 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DKLCKOFC_00169 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DKLCKOFC_00170 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DKLCKOFC_00171 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DKLCKOFC_00172 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DKLCKOFC_00173 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DKLCKOFC_00174 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DKLCKOFC_00175 2.2e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DKLCKOFC_00176 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
DKLCKOFC_00177 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DKLCKOFC_00178 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DKLCKOFC_00179 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DKLCKOFC_00180 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DKLCKOFC_00181 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DKLCKOFC_00182 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DKLCKOFC_00183 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
DKLCKOFC_00184 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DKLCKOFC_00185 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
DKLCKOFC_00186 1.4e-58 ywiC S YwiC-like protein
DKLCKOFC_00187 9.7e-90 ywiC S YwiC-like protein
DKLCKOFC_00188 6.2e-157 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
DKLCKOFC_00189 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DKLCKOFC_00190 6.9e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
DKLCKOFC_00191 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DKLCKOFC_00192 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
DKLCKOFC_00193 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DKLCKOFC_00194 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
DKLCKOFC_00195 8.9e-112
DKLCKOFC_00196 1.1e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
DKLCKOFC_00197 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
DKLCKOFC_00199 6e-241 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKLCKOFC_00200 1.4e-225 dapC E Aminotransferase class I and II
DKLCKOFC_00201 9e-61 fdxA C 4Fe-4S binding domain
DKLCKOFC_00202 9.7e-217 murB 1.3.1.98 M Cell wall formation
DKLCKOFC_00203 1.9e-25 rpmG J Ribosomal protein L33
DKLCKOFC_00207 3.4e-56 KLT Associated with various cellular activities
DKLCKOFC_00208 3.1e-128 bla1 3.5.2.6 V Beta-lactamase enzyme family
DKLCKOFC_00209 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DKLCKOFC_00210 7.2e-144
DKLCKOFC_00211 2.3e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
DKLCKOFC_00212 2e-120 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
DKLCKOFC_00213 3.2e-38 fmdB S Putative regulatory protein
DKLCKOFC_00214 1.6e-109 flgA NO SAF
DKLCKOFC_00215 9.6e-42
DKLCKOFC_00216 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
DKLCKOFC_00217 1e-237 T Forkhead associated domain
DKLCKOFC_00219 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DKLCKOFC_00220 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DKLCKOFC_00221 1.7e-182 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
DKLCKOFC_00222 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
DKLCKOFC_00224 8.8e-222 pbuO S Permease family
DKLCKOFC_00225 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DKLCKOFC_00226 3e-170 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DKLCKOFC_00227 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DKLCKOFC_00228 6.2e-180 pstA P Phosphate transport system permease
DKLCKOFC_00229 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
DKLCKOFC_00230 3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
DKLCKOFC_00231 1.4e-127 KT Transcriptional regulatory protein, C terminal
DKLCKOFC_00232 8.5e-246 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
DKLCKOFC_00233 1.9e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DKLCKOFC_00234 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DKLCKOFC_00235 9.7e-109 K helix_turn_helix, Arsenical Resistance Operon Repressor
DKLCKOFC_00236 3.4e-242 EGP Major facilitator Superfamily
DKLCKOFC_00237 3.3e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DKLCKOFC_00238 2.3e-166 L Excalibur calcium-binding domain
DKLCKOFC_00239 1.6e-268 pepC 3.4.22.40 E Peptidase C1-like family
DKLCKOFC_00240 7.4e-54 D nuclear chromosome segregation
DKLCKOFC_00241 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DKLCKOFC_00242 1.1e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DKLCKOFC_00243 1.6e-185 yfiH Q Multi-copper polyphenol oxidoreductase laccase
DKLCKOFC_00244 0.0 yegQ O Peptidase family U32 C-terminal domain
DKLCKOFC_00245 1.7e-96 L Transposase and inactivated derivatives IS30 family
DKLCKOFC_00246 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
DKLCKOFC_00247 6.3e-41 nrdH O Glutaredoxin
DKLCKOFC_00248 5.6e-98 nrdI F Probably involved in ribonucleotide reductase function
DKLCKOFC_00249 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKLCKOFC_00250 9.1e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKLCKOFC_00251 9.2e-74 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DKLCKOFC_00252 0.0 S Predicted membrane protein (DUF2207)
DKLCKOFC_00253 1.4e-93 lemA S LemA family
DKLCKOFC_00254 1.5e-40 K purine nucleotide biosynthetic process
DKLCKOFC_00255 2.6e-151 xylR K purine nucleotide biosynthetic process
DKLCKOFC_00256 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DKLCKOFC_00257 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DKLCKOFC_00258 8.9e-119
DKLCKOFC_00259 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
DKLCKOFC_00261 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
DKLCKOFC_00262 3.2e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DKLCKOFC_00263 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
DKLCKOFC_00264 7.2e-308 pccB I Carboxyl transferase domain
DKLCKOFC_00265 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
DKLCKOFC_00266 4.2e-93 bioY S BioY family
DKLCKOFC_00267 4e-153 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
DKLCKOFC_00268 0.0
DKLCKOFC_00269 5.9e-146 QT PucR C-terminal helix-turn-helix domain
DKLCKOFC_00270 9.5e-132 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DKLCKOFC_00271 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DKLCKOFC_00272 9.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DKLCKOFC_00273 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DKLCKOFC_00274 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DKLCKOFC_00275 4.1e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DKLCKOFC_00276 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DKLCKOFC_00277 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DKLCKOFC_00279 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
DKLCKOFC_00280 1.2e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DKLCKOFC_00282 1e-44
DKLCKOFC_00283 0.0 K RNA polymerase II activating transcription factor binding
DKLCKOFC_00284 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
DKLCKOFC_00285 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DKLCKOFC_00287 1.3e-102 mntP P Probably functions as a manganese efflux pump
DKLCKOFC_00288 1.4e-125
DKLCKOFC_00289 1.8e-133 KT Transcriptional regulatory protein, C terminal
DKLCKOFC_00290 1.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DKLCKOFC_00291 4.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
DKLCKOFC_00292 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DKLCKOFC_00293 0.0 S domain protein
DKLCKOFC_00294 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
DKLCKOFC_00295 9.1e-90 lrp_3 K helix_turn_helix ASNC type
DKLCKOFC_00296 7.2e-236 E Aminotransferase class I and II
DKLCKOFC_00297 0.0 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DKLCKOFC_00298 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
DKLCKOFC_00299 2.5e-52 S Protein of unknown function (DUF2469)
DKLCKOFC_00300 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
DKLCKOFC_00301 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKLCKOFC_00302 1.1e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DKLCKOFC_00303 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKLCKOFC_00304 3.7e-82 V ABC transporter
DKLCKOFC_00305 1e-60 V ABC transporter
DKLCKOFC_00306 5.9e-155 spoU 2.1.1.185 J RNA methyltransferase TrmH family
DKLCKOFC_00307 7.5e-49 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DKLCKOFC_00308 3e-50 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DKLCKOFC_00309 2.9e-214 rmuC S RmuC family
DKLCKOFC_00310 9.6e-43 csoR S Metal-sensitive transcriptional repressor
DKLCKOFC_00311 0.0 pacS 3.6.3.54 P E1-E2 ATPase
DKLCKOFC_00312 0.0 ubiB S ABC1 family
DKLCKOFC_00313 3.5e-19 S granule-associated protein
DKLCKOFC_00314 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
DKLCKOFC_00315 2.5e-281 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
DKLCKOFC_00316 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DKLCKOFC_00317 3.5e-250 dinF V MatE
DKLCKOFC_00318 3.5e-20 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
DKLCKOFC_00319 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
DKLCKOFC_00320 1e-54 glnB K Nitrogen regulatory protein P-II
DKLCKOFC_00321 3.8e-219 amt U Ammonium Transporter Family
DKLCKOFC_00322 6.2e-203 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DKLCKOFC_00324 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
DKLCKOFC_00325 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
DKLCKOFC_00326 0.0 S Glycosyl hydrolases related to GH101 family, GH129
DKLCKOFC_00327 1.4e-305 pepD E Peptidase family C69
DKLCKOFC_00329 2.9e-19 XK26_04485 P Cobalt transport protein
DKLCKOFC_00330 1.1e-68 XK26_04485 P Cobalt transport protein
DKLCKOFC_00331 2e-82
DKLCKOFC_00332 0.0 V ABC transporter transmembrane region
DKLCKOFC_00333 1.8e-301 V ABC transporter, ATP-binding protein
DKLCKOFC_00334 2.7e-82 K Winged helix DNA-binding domain
DKLCKOFC_00335 5.8e-305 M LPXTG cell wall anchor motif
DKLCKOFC_00336 0.0 M chlorophyll binding
DKLCKOFC_00337 2e-180 3.4.22.70 M Sortase family
DKLCKOFC_00339 4.7e-162 S Sucrose-6F-phosphate phosphohydrolase
DKLCKOFC_00340 3.5e-241 S Putative ABC-transporter type IV
DKLCKOFC_00341 7e-81
DKLCKOFC_00342 5.8e-33 Q phosphatase activity
DKLCKOFC_00343 1.2e-295 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
DKLCKOFC_00344 3.3e-42 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
DKLCKOFC_00345 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
DKLCKOFC_00346 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DKLCKOFC_00347 4.6e-67 S haloacid dehalogenase-like hydrolase
DKLCKOFC_00348 3.6e-131 yydK K UTRA
DKLCKOFC_00349 1.3e-70 S FMN_bind
DKLCKOFC_00350 1.8e-147 macB V ABC transporter, ATP-binding protein
DKLCKOFC_00351 5.9e-204 Z012_06715 V FtsX-like permease family
DKLCKOFC_00352 9.7e-223 macB_2 V ABC transporter permease
DKLCKOFC_00353 1.6e-233 S Predicted membrane protein (DUF2318)
DKLCKOFC_00354 5.4e-108 tpd P Fe2+ transport protein
DKLCKOFC_00355 3.9e-307 efeU_1 P Iron permease FTR1 family
DKLCKOFC_00356 2e-18 G MFS/sugar transport protein
DKLCKOFC_00357 1.1e-200 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DKLCKOFC_00358 2e-56 S Fic/DOC family
DKLCKOFC_00359 1.2e-289 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DKLCKOFC_00360 5e-38 ptsH G PTS HPr component phosphorylation site
DKLCKOFC_00361 4.4e-200 K helix_turn _helix lactose operon repressor
DKLCKOFC_00362 6.3e-213 holB 2.7.7.7 L DNA polymerase III
DKLCKOFC_00363 1.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DKLCKOFC_00364 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DKLCKOFC_00365 6.4e-183 3.6.1.27 I PAP2 superfamily
DKLCKOFC_00366 0.0 vpr M PA domain
DKLCKOFC_00367 3e-122 yplQ S Haemolysin-III related
DKLCKOFC_00368 4.6e-232 glf 5.4.99.9 M UDP-galactopyranose mutase
DKLCKOFC_00369 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DKLCKOFC_00370 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKLCKOFC_00371 3.9e-278 S Calcineurin-like phosphoesterase
DKLCKOFC_00372 4.3e-14 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
DKLCKOFC_00373 1.2e-288 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
DKLCKOFC_00374 1.7e-116
DKLCKOFC_00375 1.1e-211 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DKLCKOFC_00377 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
DKLCKOFC_00378 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
DKLCKOFC_00379 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DKLCKOFC_00380 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
DKLCKOFC_00381 3.2e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
DKLCKOFC_00382 2e-56 S TIGRFAM helicase secretion neighborhood TadE-like protein
DKLCKOFC_00383 1.9e-41 S Protein of unknown function (DUF4244)
DKLCKOFC_00384 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
DKLCKOFC_00385 1.4e-14 gspF NU Type II secretion system (T2SS), protein F
DKLCKOFC_00386 7.4e-121 U Type ii secretion system
DKLCKOFC_00387 3.4e-191 cpaF U Type II IV secretion system protein
DKLCKOFC_00388 7.5e-152 cpaE D bacterial-type flagellum organization
DKLCKOFC_00390 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DKLCKOFC_00391 5.1e-220 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
DKLCKOFC_00392 3.3e-90
DKLCKOFC_00393 2.2e-57 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DKLCKOFC_00394 2.5e-208 S Glycosyltransferase, group 2 family protein
DKLCKOFC_00395 5.2e-262
DKLCKOFC_00397 8.7e-27 thiS 2.8.1.10 H ThiS family
DKLCKOFC_00398 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DKLCKOFC_00399 0.0 S Psort location Cytoplasmic, score 8.87
DKLCKOFC_00400 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
DKLCKOFC_00401 1.1e-246 V ABC transporter permease
DKLCKOFC_00402 1.1e-181 V ABC transporter
DKLCKOFC_00403 2.1e-137 T HD domain
DKLCKOFC_00404 3.3e-166 S Glutamine amidotransferase domain
DKLCKOFC_00405 0.0 kup P Transport of potassium into the cell
DKLCKOFC_00406 1.3e-184 tatD L TatD related DNase
DKLCKOFC_00407 4.2e-275 xylR 5.3.1.12 G MFS/sugar transport protein
DKLCKOFC_00409 8.9e-87 K Transcriptional regulator
DKLCKOFC_00410 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKLCKOFC_00411 3.6e-130
DKLCKOFC_00412 8.6e-59
DKLCKOFC_00413 4.6e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DKLCKOFC_00414 2.7e-126 dedA S SNARE associated Golgi protein
DKLCKOFC_00416 3.5e-134 S HAD hydrolase, family IA, variant 3
DKLCKOFC_00417 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
DKLCKOFC_00418 1.8e-230 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
DKLCKOFC_00419 1.1e-186 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
DKLCKOFC_00420 2.6e-86 hspR K transcriptional regulator, MerR family
DKLCKOFC_00421 7.1e-173 dnaJ1 O DnaJ molecular chaperone homology domain
DKLCKOFC_00423 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DKLCKOFC_00424 0.0 dnaK O Heat shock 70 kDa protein
DKLCKOFC_00425 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
DKLCKOFC_00426 2.9e-190 K Psort location Cytoplasmic, score
DKLCKOFC_00429 1.8e-138 G Phosphoglycerate mutase family
DKLCKOFC_00430 3e-69 S Protein of unknown function (DUF4235)
DKLCKOFC_00431 1.2e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
DKLCKOFC_00432 1.1e-45
DKLCKOFC_00433 7e-183 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
DKLCKOFC_00434 1.5e-177 2.7.1.2 GK ROK family
DKLCKOFC_00435 6.4e-218 GK ROK family
DKLCKOFC_00436 4.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
DKLCKOFC_00437 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DKLCKOFC_00438 1.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DKLCKOFC_00439 8.9e-303 ybiT S ABC transporter
DKLCKOFC_00440 4.5e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
DKLCKOFC_00441 1.1e-230 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DKLCKOFC_00442 3.9e-37 K Transcriptional regulatory protein, C terminal
DKLCKOFC_00443 1.9e-41 K Transcriptional regulatory protein, C terminal
DKLCKOFC_00444 7.1e-28 V MacB-like periplasmic core domain
DKLCKOFC_00445 6.1e-77
DKLCKOFC_00446 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DKLCKOFC_00447 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DKLCKOFC_00448 2.1e-182 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
DKLCKOFC_00449 1.5e-177 rapZ S Displays ATPase and GTPase activities
DKLCKOFC_00450 3.1e-173 whiA K May be required for sporulation
DKLCKOFC_00451 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
DKLCKOFC_00452 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DKLCKOFC_00453 8e-33 secG U Preprotein translocase SecG subunit
DKLCKOFC_00454 5.3e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DKLCKOFC_00455 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
DKLCKOFC_00456 3.1e-243 mepA_6 V MatE
DKLCKOFC_00458 7.5e-253 brnQ U Component of the transport system for branched-chain amino acids
DKLCKOFC_00459 1.2e-143 yoaK S Protein of unknown function (DUF1275)
DKLCKOFC_00460 2.3e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DKLCKOFC_00461 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
DKLCKOFC_00462 2.3e-221 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DKLCKOFC_00463 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DKLCKOFC_00464 7.1e-160 G Fructosamine kinase
DKLCKOFC_00465 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DKLCKOFC_00466 2.8e-156 S PAC2 family
DKLCKOFC_00470 2.6e-262
DKLCKOFC_00473 2.2e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DKLCKOFC_00474 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DKLCKOFC_00475 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
DKLCKOFC_00476 1e-131 yebC K transcriptional regulatory protein
DKLCKOFC_00477 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DKLCKOFC_00478 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DKLCKOFC_00479 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DKLCKOFC_00480 2.6e-44 yajC U Preprotein translocase subunit
DKLCKOFC_00481 2.1e-100 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DKLCKOFC_00482 2.5e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DKLCKOFC_00483 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DKLCKOFC_00484 2.7e-244
DKLCKOFC_00485 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DKLCKOFC_00486 5.7e-30
DKLCKOFC_00487 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DKLCKOFC_00488 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DKLCKOFC_00489 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
DKLCKOFC_00490 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DKLCKOFC_00491 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DKLCKOFC_00492 5.2e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DKLCKOFC_00493 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
DKLCKOFC_00494 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
DKLCKOFC_00495 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
DKLCKOFC_00496 1e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DKLCKOFC_00497 1.2e-172 S Bacterial protein of unknown function (DUF881)
DKLCKOFC_00498 2.6e-31 sbp S Protein of unknown function (DUF1290)
DKLCKOFC_00499 2.6e-141 S Bacterial protein of unknown function (DUF881)
DKLCKOFC_00500 7.3e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
DKLCKOFC_00501 2.7e-120 K helix_turn_helix, mercury resistance
DKLCKOFC_00502 7.3e-62
DKLCKOFC_00504 1.3e-96 L DNA integration
DKLCKOFC_00505 4.7e-125 S GyrI-like small molecule binding domain
DKLCKOFC_00506 4.2e-35 pgp 3.1.3.18 S HAD-hyrolase-like
DKLCKOFC_00507 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
DKLCKOFC_00508 0.0 helY L DEAD DEAH box helicase
DKLCKOFC_00509 7.7e-52
DKLCKOFC_00510 0.0 pafB K WYL domain
DKLCKOFC_00511 6.3e-287 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
DKLCKOFC_00513 1.2e-88 dkgB S Oxidoreductase, aldo keto reductase family protein
DKLCKOFC_00514 7.1e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
DKLCKOFC_00515 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DKLCKOFC_00516 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DKLCKOFC_00517 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
DKLCKOFC_00518 2e-91 T Domain of unknown function (DUF4234)
DKLCKOFC_00519 9.3e-101 K Bacterial regulatory proteins, tetR family
DKLCKOFC_00520 1.6e-18
DKLCKOFC_00521 3.1e-49 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
DKLCKOFC_00522 1.4e-40 K Helix-turn-helix
DKLCKOFC_00523 7e-225 hipA 2.7.11.1 S HipA N-terminal domain
DKLCKOFC_00524 1.1e-65 4.1.1.44 S Cupin domain
DKLCKOFC_00525 4e-176 S Membrane transport protein
DKLCKOFC_00526 3.8e-93 laaE K Transcriptional regulator PadR-like family
DKLCKOFC_00527 7.9e-134 magIII L endonuclease III
DKLCKOFC_00528 8.1e-131 S Enoyl-(Acyl carrier protein) reductase
DKLCKOFC_00529 5.2e-243 vbsD V MatE
DKLCKOFC_00530 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DKLCKOFC_00531 1.9e-15 KLT Protein tyrosine kinase
DKLCKOFC_00533 9.4e-145
DKLCKOFC_00534 4.7e-196 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
DKLCKOFC_00535 1e-16 K MerR family regulatory protein
DKLCKOFC_00536 1.1e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DKLCKOFC_00537 8.2e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DKLCKOFC_00538 7.7e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
DKLCKOFC_00539 2.6e-180 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
DKLCKOFC_00540 4.7e-279 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DKLCKOFC_00541 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
DKLCKOFC_00542 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DKLCKOFC_00543 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
DKLCKOFC_00545 9e-161 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
DKLCKOFC_00546 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DKLCKOFC_00550 2.2e-127 3.5.1.28 M NLP P60 protein
DKLCKOFC_00551 6.5e-67 S SPP1 phage holin
DKLCKOFC_00552 1.3e-69
DKLCKOFC_00553 6.2e-50 MU outer membrane autotransporter barrel domain protein
DKLCKOFC_00554 4e-214
DKLCKOFC_00555 2.8e-64
DKLCKOFC_00556 0.0 S Prophage endopeptidase tail
DKLCKOFC_00557 1.8e-147 S phage tail
DKLCKOFC_00558 0.0 S Phage-related minor tail protein
DKLCKOFC_00559 6.3e-53
DKLCKOFC_00560 7.7e-83
DKLCKOFC_00561 3.6e-94
DKLCKOFC_00562 4.9e-72
DKLCKOFC_00563 8.8e-72
DKLCKOFC_00564 1.3e-78
DKLCKOFC_00565 2.2e-90
DKLCKOFC_00566 8.1e-65
DKLCKOFC_00567 3.8e-176 S Phage capsid family
DKLCKOFC_00568 3.7e-78
DKLCKOFC_00570 1.1e-43
DKLCKOFC_00571 7.4e-241
DKLCKOFC_00572 5.5e-280 S Phage portal protein, SPP1 Gp6-like
DKLCKOFC_00573 0.0 S Terminase
DKLCKOFC_00574 4.8e-69
DKLCKOFC_00575 6.7e-115 S Bifunctional DNA primase/polymerase, N-terminal
DKLCKOFC_00576 8.1e-66
DKLCKOFC_00579 3.2e-32 K Transcriptional regulator
DKLCKOFC_00581 1.5e-73 S HicB_like antitoxin of bacterial toxin-antitoxin system
DKLCKOFC_00582 1.3e-34 N HicA toxin of bacterial toxin-antitoxin,
DKLCKOFC_00583 9.7e-143
DKLCKOFC_00585 3e-50
DKLCKOFC_00587 1.9e-109 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
DKLCKOFC_00588 2.6e-81 V HNH endonuclease
DKLCKOFC_00589 1.5e-26
DKLCKOFC_00590 1.9e-145 K Transcriptional regulator
DKLCKOFC_00591 1.4e-275 K ParB-like nuclease domain
DKLCKOFC_00592 8.6e-93 ssb1 L Single-strand binding protein family
DKLCKOFC_00594 5.6e-36
DKLCKOFC_00596 2.2e-37
DKLCKOFC_00598 6.8e-164 IQ KR domain
DKLCKOFC_00599 6.7e-65 4.2.1.68 M Enolase C-terminal domain-like
DKLCKOFC_00600 5.3e-18 4.2.1.68 M carboxylic acid catabolic process
DKLCKOFC_00601 6.3e-185 K Bacterial regulatory proteins, lacI family
DKLCKOFC_00604 1.4e-118 cyaA 4.6.1.1 S CYTH
DKLCKOFC_00605 8.5e-163 trxA2 O Tetratricopeptide repeat
DKLCKOFC_00606 7.9e-180
DKLCKOFC_00607 5.8e-189
DKLCKOFC_00608 1.2e-164 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
DKLCKOFC_00609 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DKLCKOFC_00610 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DKLCKOFC_00611 4.9e-128
DKLCKOFC_00612 2.1e-131 K Bacterial regulatory proteins, tetR family
DKLCKOFC_00613 1.7e-50 G Transmembrane secretion effector
DKLCKOFC_00614 2.6e-158 G Transmembrane secretion effector
DKLCKOFC_00615 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DKLCKOFC_00616 2.3e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
DKLCKOFC_00617 7.1e-182 S CAAX protease self-immunity
DKLCKOFC_00619 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
DKLCKOFC_00620 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DKLCKOFC_00621 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DKLCKOFC_00622 8.2e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
DKLCKOFC_00623 2.2e-251 S Calcineurin-like phosphoesterase
DKLCKOFC_00626 3.5e-67 S Domain of unknown function (DUF4143)
DKLCKOFC_00627 5.6e-103 S Domain of unknown function (DUF4143)
DKLCKOFC_00628 6.3e-298 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKLCKOFC_00630 1.1e-124 S HAD hydrolase, family IA, variant 3
DKLCKOFC_00631 8.6e-201 P NMT1/THI5 like
DKLCKOFC_00632 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
DKLCKOFC_00633 5.8e-145
DKLCKOFC_00634 1.1e-126 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
DKLCKOFC_00635 4e-262 EGP Major facilitator Superfamily
DKLCKOFC_00636 6.8e-98 S GtrA-like protein
DKLCKOFC_00637 1.3e-62 S Macrophage migration inhibitory factor (MIF)
DKLCKOFC_00638 1.3e-287 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
DKLCKOFC_00639 0.0 pepD E Peptidase family C69
DKLCKOFC_00640 1.3e-107 S Phosphatidylethanolamine-binding protein
DKLCKOFC_00641 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
DKLCKOFC_00642 0.0 lmrA2 V ABC transporter transmembrane region
DKLCKOFC_00643 0.0 lmrA1 V ABC transporter, ATP-binding protein
DKLCKOFC_00644 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
DKLCKOFC_00645 3.3e-191 1.1.1.65 C Aldo/keto reductase family
DKLCKOFC_00647 4e-100 M Belongs to the glycosyl hydrolase 30 family
DKLCKOFC_00648 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
DKLCKOFC_00650 1.3e-258 L Phage integrase, N-terminal SAM-like domain
DKLCKOFC_00653 4.7e-105
DKLCKOFC_00654 0.0 ltrBE1 U Relaxase/Mobilisation nuclease domain
DKLCKOFC_00655 1.4e-59 S Bacterial mobilisation protein (MobC)
DKLCKOFC_00656 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
DKLCKOFC_00657 2e-180 V Abi-like protein
DKLCKOFC_00658 6.5e-229 3.1.21.3 V Type I restriction modification DNA specificity domain
DKLCKOFC_00660 7.6e-299 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
DKLCKOFC_00661 5.6e-272
DKLCKOFC_00662 1.4e-13
DKLCKOFC_00663 1.4e-90 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
DKLCKOFC_00664 5e-116 K WHG domain
DKLCKOFC_00665 3.6e-37 L Psort location Cytoplasmic, score 8.87
DKLCKOFC_00666 2.1e-134 L Integrase core domain
DKLCKOFC_00667 3.5e-41 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
DKLCKOFC_00668 1.5e-265 EGP Major Facilitator Superfamily
DKLCKOFC_00669 1.2e-132
DKLCKOFC_00670 2.9e-243 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DKLCKOFC_00671 5.5e-55 L HNH endonuclease
DKLCKOFC_00672 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DKLCKOFC_00673 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DKLCKOFC_00674 1.6e-105 L Transposase
DKLCKOFC_00675 4.2e-42 XAC3035 O Glutaredoxin
DKLCKOFC_00676 7.4e-151 S Virulence factor BrkB
DKLCKOFC_00677 7.6e-100 bcp 1.11.1.15 O Redoxin
DKLCKOFC_00678 1.2e-39 E ABC transporter
DKLCKOFC_00679 6.7e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DKLCKOFC_00680 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DKLCKOFC_00681 0.0 V FtsX-like permease family
DKLCKOFC_00682 2.6e-129 V ABC transporter
DKLCKOFC_00683 2.4e-101 K Transcriptional regulator C-terminal region
DKLCKOFC_00684 1.8e-276 aroP E aromatic amino acid transport protein AroP K03293
DKLCKOFC_00685 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DKLCKOFC_00687 8.8e-184 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
DKLCKOFC_00688 7.1e-112 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DKLCKOFC_00689 5.4e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKLCKOFC_00690 1.3e-154 sapF E ATPases associated with a variety of cellular activities
DKLCKOFC_00691 2.6e-141 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
DKLCKOFC_00692 1.6e-161 EP Binding-protein-dependent transport system inner membrane component
DKLCKOFC_00693 4.6e-169 P Binding-protein-dependent transport system inner membrane component
DKLCKOFC_00694 1.3e-309 E ABC transporter, substrate-binding protein, family 5
DKLCKOFC_00695 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DKLCKOFC_00696 1.7e-276 G Bacterial extracellular solute-binding protein
DKLCKOFC_00697 3.8e-66 G carbohydrate transport
DKLCKOFC_00698 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DKLCKOFC_00699 2.5e-124 G ABC transporter permease
DKLCKOFC_00700 2.9e-190 K Periplasmic binding protein domain
DKLCKOFC_00701 8.5e-20 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DKLCKOFC_00702 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
DKLCKOFC_00703 3.3e-22 L Helix-turn-helix domain
DKLCKOFC_00704 3.4e-18 S Protein of unknown function (DUF2442)
DKLCKOFC_00705 2.6e-16 K Helix-turn-helix domain
DKLCKOFC_00706 2.9e-107 L Belongs to the 'phage' integrase family
DKLCKOFC_00707 1.3e-58 3.1.21.3 V Type I restriction modification DNA specificity domain
DKLCKOFC_00708 5.2e-244 hsdM 2.1.1.72 V HsdM N-terminal domain
DKLCKOFC_00709 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
DKLCKOFC_00710 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DKLCKOFC_00711 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
DKLCKOFC_00712 3e-273 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
DKLCKOFC_00713 1.8e-127 XK27_08050 O prohibitin homologues
DKLCKOFC_00714 2.2e-243 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
DKLCKOFC_00715 4.1e-231 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DKLCKOFC_00716 4.7e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
DKLCKOFC_00717 8.1e-227 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DKLCKOFC_00718 0.0 macB_2 V ATPases associated with a variety of cellular activities
DKLCKOFC_00719 0.0 ctpE P E1-E2 ATPase
DKLCKOFC_00720 3.6e-93 K acetyltransferase
DKLCKOFC_00721 1.7e-79 EGP Major Facilitator Superfamily
DKLCKOFC_00722 7.1e-197 yghZ C Aldo/keto reductase family
DKLCKOFC_00723 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
DKLCKOFC_00724 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
DKLCKOFC_00725 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
DKLCKOFC_00726 1.5e-121 S Short repeat of unknown function (DUF308)
DKLCKOFC_00727 0.0 pepO 3.4.24.71 O Peptidase family M13
DKLCKOFC_00728 2.1e-97 L Single-strand binding protein family
DKLCKOFC_00729 2.4e-170
DKLCKOFC_00730 2.4e-30
DKLCKOFC_00731 1.2e-154 S Domain of unknown function (DUF4357)
DKLCKOFC_00732 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
DKLCKOFC_00733 1e-107
DKLCKOFC_00735 1.5e-40 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
DKLCKOFC_00736 1e-178 L Phage integrase family
DKLCKOFC_00737 3.1e-83 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DKLCKOFC_00738 3.9e-29 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
DKLCKOFC_00739 2.6e-30 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
DKLCKOFC_00741 4.4e-109
DKLCKOFC_00742 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
DKLCKOFC_00743 4.1e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DKLCKOFC_00744 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DKLCKOFC_00745 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DKLCKOFC_00746 1.4e-10 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DKLCKOFC_00747 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKLCKOFC_00748 2.6e-269 yhdG E aromatic amino acid transport protein AroP K03293
DKLCKOFC_00749 1.7e-262 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DKLCKOFC_00750 1.5e-247 dgt 3.1.5.1 F Phosphohydrolase-associated domain
DKLCKOFC_00751 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DKLCKOFC_00752 3.5e-160 K Helix-turn-helix domain, rpiR family
DKLCKOFC_00753 5.8e-230 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DKLCKOFC_00754 1.4e-44 S Memo-like protein
DKLCKOFC_00756 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DKLCKOFC_00757 2.9e-179 adh3 C Zinc-binding dehydrogenase
DKLCKOFC_00758 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DKLCKOFC_00759 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DKLCKOFC_00760 4.3e-73 zur P Belongs to the Fur family
DKLCKOFC_00761 9.8e-45
DKLCKOFC_00762 7.7e-154 S TIGRFAM TIGR03943 family protein
DKLCKOFC_00763 1.4e-201 ycgR S Predicted permease
DKLCKOFC_00764 1.9e-22 J Ribosomal L32p protein family
DKLCKOFC_00765 8.2e-15 rpmJ J Ribosomal protein L36
DKLCKOFC_00766 7.4e-42 rpmE2 J Ribosomal protein L31
DKLCKOFC_00767 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DKLCKOFC_00768 2.3e-47 rpmB J Ribosomal L28 family
DKLCKOFC_00769 8.7e-139 S cobalamin synthesis protein
DKLCKOFC_00770 3.3e-161 P Zinc-uptake complex component A periplasmic
DKLCKOFC_00771 0.0 lysX S Uncharacterised conserved protein (DUF2156)
DKLCKOFC_00772 1.7e-246 S Putative esterase
DKLCKOFC_00773 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DKLCKOFC_00774 9.4e-239 purD 6.3.4.13 F Belongs to the GARS family
DKLCKOFC_00775 6.8e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DKLCKOFC_00776 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DKLCKOFC_00777 5.5e-305 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
DKLCKOFC_00778 2e-32
DKLCKOFC_00779 4.7e-69 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DKLCKOFC_00780 8.9e-33 K DNA-binding transcription factor activity
DKLCKOFC_00781 4.3e-152 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
DKLCKOFC_00782 2.1e-93 S Protein of unknown function (DUF4230)
DKLCKOFC_00783 3.3e-110
DKLCKOFC_00784 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
DKLCKOFC_00785 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DKLCKOFC_00786 3.7e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DKLCKOFC_00787 0.0 M Parallel beta-helix repeats
DKLCKOFC_00788 1.6e-227 M Glycosyl transferase 4-like domain
DKLCKOFC_00789 1.3e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
DKLCKOFC_00791 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DKLCKOFC_00792 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DKLCKOFC_00793 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DKLCKOFC_00794 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DKLCKOFC_00795 0.0 S Esterase-like activity of phytase
DKLCKOFC_00796 1e-191 EGP Transmembrane secretion effector
DKLCKOFC_00798 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DKLCKOFC_00799 3.2e-84 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DKLCKOFC_00800 1.2e-238 carA 6.3.5.5 F Belongs to the CarA family
DKLCKOFC_00801 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
DKLCKOFC_00802 4.4e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DKLCKOFC_00803 0.0 S Protein of unknown function DUF262
DKLCKOFC_00804 9.1e-116 K helix_turn_helix, Lux Regulon
DKLCKOFC_00805 1.7e-265 T Histidine kinase
DKLCKOFC_00806 1e-97 S Domain of unknown function (DUF5067)
DKLCKOFC_00807 6.6e-132 ybhL S Belongs to the BI1 family
DKLCKOFC_00808 7.5e-172 ydeD EG EamA-like transporter family
DKLCKOFC_00809 2.3e-72 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
DKLCKOFC_00810 5.7e-280 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DKLCKOFC_00811 6.1e-129 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DKLCKOFC_00812 1.2e-137 fic D Fic/DOC family
DKLCKOFC_00813 0.0 ftsK D FtsK SpoIIIE family protein
DKLCKOFC_00814 5.4e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DKLCKOFC_00815 6.5e-96 cinA 3.5.1.42 S Belongs to the CinA family
DKLCKOFC_00816 7.3e-81 K Helix-turn-helix XRE-family like proteins
DKLCKOFC_00817 3.7e-40 S Protein of unknown function (DUF3046)
DKLCKOFC_00818 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DKLCKOFC_00819 2.9e-87 recX S Modulates RecA activity
DKLCKOFC_00820 1e-07
DKLCKOFC_00821 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DKLCKOFC_00822 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DKLCKOFC_00823 3.6e-25 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DKLCKOFC_00824 6.4e-193 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DKLCKOFC_00825 1.5e-109
DKLCKOFC_00826 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
DKLCKOFC_00827 0.0 pknL 2.7.11.1 KLT PASTA
DKLCKOFC_00828 1e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
DKLCKOFC_00829 1e-122
DKLCKOFC_00830 4.5e-179 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DKLCKOFC_00831 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DKLCKOFC_00832 8.9e-278 aspA 4.3.1.1 E Fumarase C C-terminus
DKLCKOFC_00833 3.2e-45 S Protein of unknown function (DUF2975)
DKLCKOFC_00834 3e-25 yozG K Cro/C1-type HTH DNA-binding domain
DKLCKOFC_00835 0.0 lhr L DEAD DEAH box helicase
DKLCKOFC_00836 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DKLCKOFC_00837 6.5e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
DKLCKOFC_00838 1.4e-187 S Protein of unknown function (DUF3071)
DKLCKOFC_00839 1.4e-47 S Domain of unknown function (DUF4193)
DKLCKOFC_00840 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DKLCKOFC_00841 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DKLCKOFC_00842 2.7e-28
DKLCKOFC_00843 1.4e-12
DKLCKOFC_00844 2.5e-208 E Belongs to the peptidase S1B family
DKLCKOFC_00845 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
DKLCKOFC_00846 1.1e-49 relB L RelB antitoxin
DKLCKOFC_00847 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DKLCKOFC_00848 4.6e-165 S Sucrose-6F-phosphate phosphohydrolase
DKLCKOFC_00849 3.3e-87 P ABC-type metal ion transport system permease component
DKLCKOFC_00850 2.7e-224 S Peptidase dimerisation domain
DKLCKOFC_00851 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKLCKOFC_00852 6.4e-40
DKLCKOFC_00853 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
DKLCKOFC_00854 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DKLCKOFC_00855 4.4e-114 S Protein of unknown function (DUF3000)
DKLCKOFC_00856 2.7e-249 rnd 3.1.13.5 J 3'-5' exonuclease
DKLCKOFC_00857 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DKLCKOFC_00858 2e-253 clcA_2 P Voltage gated chloride channel
DKLCKOFC_00859 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DKLCKOFC_00860 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DKLCKOFC_00861 1.3e-243 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DKLCKOFC_00866 1.3e-234 patB 4.4.1.8 E Aminotransferase, class I II
DKLCKOFC_00867 1.3e-224 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DKLCKOFC_00868 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
DKLCKOFC_00869 4.4e-118 safC S O-methyltransferase
DKLCKOFC_00870 1.1e-181 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
DKLCKOFC_00871 1.1e-70 yraN L Belongs to the UPF0102 family
DKLCKOFC_00872 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
DKLCKOFC_00873 4.1e-281 dprA 5.99.1.2 LU DNA recombination-mediator protein A
DKLCKOFC_00874 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
DKLCKOFC_00875 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DKLCKOFC_00876 1.6e-157 S Putative ABC-transporter type IV
DKLCKOFC_00877 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
DKLCKOFC_00879 4e-162 V ABC transporter, ATP-binding protein
DKLCKOFC_00880 0.0 MV MacB-like periplasmic core domain
DKLCKOFC_00881 0.0 phoN I PAP2 superfamily
DKLCKOFC_00882 2.8e-129 K helix_turn_helix, Lux Regulon
DKLCKOFC_00883 0.0 tcsS2 T Histidine kinase
DKLCKOFC_00884 1.9e-264 pip 3.4.11.5 S alpha/beta hydrolase fold
DKLCKOFC_00885 2.7e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DKLCKOFC_00886 1.6e-166 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
DKLCKOFC_00887 2.7e-146 P NLPA lipoprotein
DKLCKOFC_00888 3.8e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
DKLCKOFC_00889 7.8e-183 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
DKLCKOFC_00890 7.5e-203 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DKLCKOFC_00891 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
DKLCKOFC_00892 8.4e-229 mtnE 2.6.1.83 E Aminotransferase class I and II
DKLCKOFC_00893 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DKLCKOFC_00894 6.3e-246 XK27_00240 K Fic/DOC family
DKLCKOFC_00895 2.3e-120 E Psort location Cytoplasmic, score 8.87
DKLCKOFC_00896 5.6e-59 yccF S Inner membrane component domain
DKLCKOFC_00897 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
DKLCKOFC_00898 2.5e-66 S Cupin 2, conserved barrel domain protein
DKLCKOFC_00899 1.1e-255 KLT Protein tyrosine kinase
DKLCKOFC_00900 4.5e-79 K Psort location Cytoplasmic, score
DKLCKOFC_00901 5.9e-148
DKLCKOFC_00902 2.7e-22
DKLCKOFC_00903 5.5e-199 S Short C-terminal domain
DKLCKOFC_00904 2.7e-87 S Helix-turn-helix
DKLCKOFC_00905 1.1e-65 S Zincin-like metallopeptidase
DKLCKOFC_00906 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
DKLCKOFC_00907 2e-39
DKLCKOFC_00908 3.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DKLCKOFC_00909 2.1e-125 ypfH S Phospholipase/Carboxylesterase
DKLCKOFC_00910 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
DKLCKOFC_00912 1.2e-288 2.4.1.166 GT2 M Glycosyltransferase like family 2
DKLCKOFC_00913 2.9e-119 3.1.3.27 E haloacid dehalogenase-like hydrolase
DKLCKOFC_00914 3.5e-146 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
DKLCKOFC_00915 3.2e-187 MA20_14895 S Conserved hypothetical protein 698
DKLCKOFC_00916 1.6e-54 estB S Phospholipase/Carboxylesterase
DKLCKOFC_00917 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
DKLCKOFC_00918 1.4e-237 rutG F Permease family
DKLCKOFC_00919 6.9e-83 K AraC-like ligand binding domain
DKLCKOFC_00921 3e-53 IQ oxidoreductase activity
DKLCKOFC_00922 2.5e-136 ybbM V Uncharacterised protein family (UPF0014)
DKLCKOFC_00923 3.4e-135 ybbL V ATPases associated with a variety of cellular activities
DKLCKOFC_00924 5.4e-161 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKLCKOFC_00925 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DKLCKOFC_00926 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
DKLCKOFC_00927 5.1e-87
DKLCKOFC_00928 1.1e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DKLCKOFC_00929 7.9e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DKLCKOFC_00930 3.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DKLCKOFC_00931 1.9e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
DKLCKOFC_00932 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DKLCKOFC_00933 3.2e-84 argR K Regulates arginine biosynthesis genes
DKLCKOFC_00934 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DKLCKOFC_00935 2.6e-105 3.1.21.3 V type I restriction modification DNA specificity domain
DKLCKOFC_00936 4.3e-270 K Putative DNA-binding domain
DKLCKOFC_00937 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
DKLCKOFC_00938 1.4e-281 argH 4.3.2.1 E argininosuccinate lyase
DKLCKOFC_00939 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
DKLCKOFC_00940 3.5e-143 S Putative ABC-transporter type IV
DKLCKOFC_00941 1.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DKLCKOFC_00942 3.6e-159 L Tetratricopeptide repeat
DKLCKOFC_00943 7.3e-189 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
DKLCKOFC_00945 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DKLCKOFC_00946 1.6e-99
DKLCKOFC_00947 6.8e-116 trkA P TrkA-N domain
DKLCKOFC_00948 9.5e-235 trkB P Cation transport protein
DKLCKOFC_00949 4.8e-182 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DKLCKOFC_00950 3.5e-292 recN L May be involved in recombinational repair of damaged DNA
DKLCKOFC_00951 2e-123 S Haloacid dehalogenase-like hydrolase
DKLCKOFC_00952 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
DKLCKOFC_00953 2.7e-177 V ATPases associated with a variety of cellular activities
DKLCKOFC_00954 2.8e-126 S ABC-2 family transporter protein
DKLCKOFC_00955 4e-122 S ABC-2 family transporter protein
DKLCKOFC_00956 1.9e-283 thrC 4.2.3.1 E Threonine synthase N terminus
DKLCKOFC_00957 1.4e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DKLCKOFC_00958 6.8e-93
DKLCKOFC_00959 4.7e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DKLCKOFC_00960 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKLCKOFC_00962 2.1e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DKLCKOFC_00963 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DKLCKOFC_00964 2.7e-137 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DKLCKOFC_00965 1.3e-78 S Bacterial PH domain
DKLCKOFC_00966 3.2e-255 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
DKLCKOFC_00968 3e-93
DKLCKOFC_00969 5e-133 C Putative TM nitroreductase
DKLCKOFC_00970 5.9e-142 yijF S Domain of unknown function (DUF1287)
DKLCKOFC_00971 7.8e-70 pdxH S Pfam:Pyridox_oxidase
DKLCKOFC_00972 1.3e-54 KT RESPONSE REGULATOR receiver
DKLCKOFC_00973 1.4e-192 V VanZ like family
DKLCKOFC_00974 1.1e-109 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
DKLCKOFC_00975 1.5e-95 ypjC S Putative ABC-transporter type IV
DKLCKOFC_00976 3.5e-10 CE Amino acid permease
DKLCKOFC_00977 1.2e-147 3.6.4.12
DKLCKOFC_00979 5.2e-101 EGP Major facilitator Superfamily
DKLCKOFC_00980 3e-28 EGP Major facilitator Superfamily
DKLCKOFC_00981 1.3e-163 rpoC M heme binding
DKLCKOFC_00982 4.7e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DKLCKOFC_00983 4.8e-128
DKLCKOFC_00984 2.9e-133 S SOS response associated peptidase (SRAP)
DKLCKOFC_00985 1.6e-76 qseC 2.7.13.3 T Histidine kinase
DKLCKOFC_00986 1.2e-185 S Acetyltransferase (GNAT) domain
DKLCKOFC_00988 6.9e-37 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
DKLCKOFC_00989 7e-56 K Transcriptional regulator
DKLCKOFC_00990 4.5e-88 MA20_25245 K FR47-like protein
DKLCKOFC_00991 1.2e-114 ydaF_1 J Acetyltransferase (GNAT) domain
DKLCKOFC_00992 1.1e-62 yeaO K Protein of unknown function, DUF488
DKLCKOFC_00993 9e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DKLCKOFC_00994 8.8e-284 S Psort location Cytoplasmic, score 8.87
DKLCKOFC_00995 1.7e-108 S Domain of unknown function (DUF4194)
DKLCKOFC_00996 0.0 S Psort location Cytoplasmic, score 8.87
DKLCKOFC_00997 3.4e-299 E Serine carboxypeptidase
DKLCKOFC_00998 3.6e-162 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DKLCKOFC_00999 3.7e-171 corA P CorA-like Mg2+ transporter protein
DKLCKOFC_01000 2.6e-169 ET Bacterial periplasmic substrate-binding proteins
DKLCKOFC_01001 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DKLCKOFC_01002 3.1e-84 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
DKLCKOFC_01003 0.0 comE S Competence protein
DKLCKOFC_01004 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
DKLCKOFC_01005 3.8e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
DKLCKOFC_01006 1.5e-158 yeaZ 2.3.1.234 O Glycoprotease family
DKLCKOFC_01007 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
DKLCKOFC_01008 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DKLCKOFC_01010 7e-170 M Peptidase family M23
DKLCKOFC_01011 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
DKLCKOFC_01012 3.2e-276 G ABC transporter substrate-binding protein
DKLCKOFC_01013 2.2e-240 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
DKLCKOFC_01014 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
DKLCKOFC_01015 5.7e-91
DKLCKOFC_01016 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
DKLCKOFC_01017 5.8e-88 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DKLCKOFC_01018 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
DKLCKOFC_01019 2.4e-145 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DKLCKOFC_01020 1e-127 3.2.1.8 S alpha beta
DKLCKOFC_01021 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DKLCKOFC_01022 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DKLCKOFC_01023 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
DKLCKOFC_01024 2.3e-226 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DKLCKOFC_01025 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DKLCKOFC_01026 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DKLCKOFC_01027 7.1e-308 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DKLCKOFC_01028 3.7e-208 G Bacterial extracellular solute-binding protein
DKLCKOFC_01029 1.2e-19 G Bacterial extracellular solute-binding protein
DKLCKOFC_01030 1.4e-173 G Binding-protein-dependent transport system inner membrane component
DKLCKOFC_01031 1e-168 G ABC transporter permease
DKLCKOFC_01032 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DKLCKOFC_01033 2.2e-72 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
DKLCKOFC_01034 6.1e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
DKLCKOFC_01035 1e-96
DKLCKOFC_01037 2.1e-54 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DKLCKOFC_01038 1e-119 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DKLCKOFC_01039 5.7e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
DKLCKOFC_01040 2.5e-101 divIC D Septum formation initiator
DKLCKOFC_01041 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DKLCKOFC_01042 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
DKLCKOFC_01043 1.8e-297 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
DKLCKOFC_01044 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DKLCKOFC_01045 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DKLCKOFC_01046 1.7e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
DKLCKOFC_01047 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
DKLCKOFC_01048 1e-150 GM ABC-2 type transporter
DKLCKOFC_01049 1.9e-197 GM GDP-mannose 4,6 dehydratase
DKLCKOFC_01050 5e-128 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DKLCKOFC_01053 1e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
DKLCKOFC_01054 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DKLCKOFC_01055 4e-206 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DKLCKOFC_01056 0.0 S Uncharacterised protein family (UPF0182)
DKLCKOFC_01057 2.3e-232 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
DKLCKOFC_01058 3.8e-196
DKLCKOFC_01059 3.2e-147 ytrE V ATPases associated with a variety of cellular activities
DKLCKOFC_01060 2.2e-191 V N-Acetylmuramoyl-L-alanine amidase
DKLCKOFC_01061 3e-259 argE E Peptidase dimerisation domain
DKLCKOFC_01062 5.5e-104 S Protein of unknown function (DUF3043)
DKLCKOFC_01063 5.2e-281 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKLCKOFC_01064 9.4e-144 S Domain of unknown function (DUF4191)
DKLCKOFC_01065 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
DKLCKOFC_01066 1.3e-18
DKLCKOFC_01068 5.1e-19
DKLCKOFC_01071 7.5e-160 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DKLCKOFC_01072 6.3e-210 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DKLCKOFC_01073 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DKLCKOFC_01074 0.0 S Tetratricopeptide repeat
DKLCKOFC_01075 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DKLCKOFC_01076 8.2e-72 2.8.2.22 S Arylsulfotransferase Ig-like domain
DKLCKOFC_01077 3.4e-138 bioM P ATPases associated with a variety of cellular activities
DKLCKOFC_01078 2e-213 E Aminotransferase class I and II
DKLCKOFC_01079 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
DKLCKOFC_01081 1.1e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DKLCKOFC_01082 0.0 ecfA GP ABC transporter, ATP-binding protein
DKLCKOFC_01083 5.2e-257 EGP Major facilitator Superfamily
DKLCKOFC_01085 5.5e-256 rarA L Recombination factor protein RarA
DKLCKOFC_01086 0.0 L DEAD DEAH box helicase
DKLCKOFC_01087 6e-194 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
DKLCKOFC_01088 1.5e-197 gluD E Binding-protein-dependent transport system inner membrane component
DKLCKOFC_01089 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
DKLCKOFC_01090 1.2e-146 gluB ET Belongs to the bacterial solute-binding protein 3 family
DKLCKOFC_01091 3.9e-139 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
DKLCKOFC_01092 8.2e-93 S Aminoacyl-tRNA editing domain
DKLCKOFC_01093 1.4e-63 K helix_turn_helix, Lux Regulon
DKLCKOFC_01094 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DKLCKOFC_01095 8.7e-262 hisS 6.1.1.21 J Histidyl-tRNA synthetase
DKLCKOFC_01096 1.7e-153 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
DKLCKOFC_01097 7.7e-33 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
DKLCKOFC_01101 0.0 clpC O ATPase family associated with various cellular activities (AAA)
DKLCKOFC_01102 4.7e-185 uspA T Belongs to the universal stress protein A family
DKLCKOFC_01103 9.5e-192 S Protein of unknown function (DUF3027)
DKLCKOFC_01104 3.8e-66 cspB K 'Cold-shock' DNA-binding domain
DKLCKOFC_01105 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DKLCKOFC_01106 1.6e-134 KT Response regulator receiver domain protein
DKLCKOFC_01107 1.2e-173
DKLCKOFC_01108 1.7e-10 S Proteins of 100 residues with WXG
DKLCKOFC_01109 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DKLCKOFC_01110 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
DKLCKOFC_01111 9.9e-71 S LytR cell envelope-related transcriptional attenuator
DKLCKOFC_01112 6e-143 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DKLCKOFC_01113 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
DKLCKOFC_01114 1.5e-175 S Protein of unknown function DUF58
DKLCKOFC_01115 6.4e-94
DKLCKOFC_01116 6.8e-190 S von Willebrand factor (vWF) type A domain
DKLCKOFC_01117 1.6e-148 S von Willebrand factor (vWF) type A domain
DKLCKOFC_01118 2.7e-74
DKLCKOFC_01120 4.4e-291 S PGAP1-like protein
DKLCKOFC_01121 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
DKLCKOFC_01122 0.0 S Lysylphosphatidylglycerol synthase TM region
DKLCKOFC_01123 8.1e-42 hup L Belongs to the bacterial histone-like protein family
DKLCKOFC_01124 8.5e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DKLCKOFC_01125 1.6e-10 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
DKLCKOFC_01126 2.4e-158 hisN 3.1.3.25 G Inositol monophosphatase family
DKLCKOFC_01127 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
DKLCKOFC_01128 0.0 arc O AAA ATPase forming ring-shaped complexes
DKLCKOFC_01129 4.7e-137 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
DKLCKOFC_01130 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DKLCKOFC_01131 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DKLCKOFC_01132 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DKLCKOFC_01133 9.4e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DKLCKOFC_01134 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DKLCKOFC_01135 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
DKLCKOFC_01136 1.8e-175 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DKLCKOFC_01138 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DKLCKOFC_01139 0.0 ctpE P E1-E2 ATPase
DKLCKOFC_01140 2e-109
DKLCKOFC_01141 4.5e-249 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DKLCKOFC_01142 6.1e-124 S Protein of unknown function (DUF3159)
DKLCKOFC_01143 2.1e-138 S Protein of unknown function (DUF3710)
DKLCKOFC_01144 1.1e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
DKLCKOFC_01145 3.1e-275 pepC 3.4.22.40 E Peptidase C1-like family
DKLCKOFC_01146 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
DKLCKOFC_01147 0.0 oppD P Belongs to the ABC transporter superfamily
DKLCKOFC_01148 4.6e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
DKLCKOFC_01149 1.8e-176 appB EP Binding-protein-dependent transport system inner membrane component
DKLCKOFC_01150 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
DKLCKOFC_01151 7.3e-42
DKLCKOFC_01152 1.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
DKLCKOFC_01153 5.5e-197 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
DKLCKOFC_01154 5.5e-92
DKLCKOFC_01155 0.0 typA T Elongation factor G C-terminus
DKLCKOFC_01156 8e-238 iscS1 2.8.1.7 E Aminotransferase class-V
DKLCKOFC_01157 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
DKLCKOFC_01158 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
DKLCKOFC_01159 3.7e-251 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DKLCKOFC_01160 5.6e-149 nrtR 3.6.1.55 F NUDIX hydrolase
DKLCKOFC_01161 2.5e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DKLCKOFC_01162 2.3e-148 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DKLCKOFC_01163 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
DKLCKOFC_01164 5.8e-180 xerD D recombinase XerD
DKLCKOFC_01165 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DKLCKOFC_01166 2.1e-25 rpmI J Ribosomal protein L35
DKLCKOFC_01167 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DKLCKOFC_01168 7.1e-68 S Spermine/spermidine synthase domain
DKLCKOFC_01169 8e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
DKLCKOFC_01170 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DKLCKOFC_01171 2.4e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DKLCKOFC_01173 2e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DKLCKOFC_01174 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
DKLCKOFC_01175 2e-64
DKLCKOFC_01176 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
DKLCKOFC_01177 2.6e-297 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DKLCKOFC_01178 6.8e-192 V Acetyltransferase (GNAT) domain
DKLCKOFC_01179 1.1e-228 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
DKLCKOFC_01180 9.5e-244 yxbA 6.3.1.12 S ATP-grasp
DKLCKOFC_01181 2.8e-128 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
DKLCKOFC_01182 0.0 smc D Required for chromosome condensation and partitioning
DKLCKOFC_01183 4.7e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
DKLCKOFC_01185 9.6e-97 3.6.1.55 F NUDIX domain
DKLCKOFC_01186 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
DKLCKOFC_01187 0.0 P Belongs to the ABC transporter superfamily
DKLCKOFC_01188 1.9e-190 dppC EP Binding-protein-dependent transport system inner membrane component
DKLCKOFC_01189 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
DKLCKOFC_01190 2e-305 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
DKLCKOFC_01191 1.1e-213 nagA 3.5.1.25 G Amidohydrolase family
DKLCKOFC_01192 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DKLCKOFC_01193 7e-217 GK ROK family
DKLCKOFC_01194 9.9e-132 cutC P Participates in the control of copper homeostasis
DKLCKOFC_01195 4.5e-222 GK ROK family
DKLCKOFC_01196 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
DKLCKOFC_01197 4.4e-236 G Major Facilitator Superfamily
DKLCKOFC_01198 2.3e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DKLCKOFC_01200 1.3e-37
DKLCKOFC_01201 4.7e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
DKLCKOFC_01202 1.8e-295 murC 6.3.2.8 M Belongs to the MurCDEF family
DKLCKOFC_01203 1.7e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DKLCKOFC_01204 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
DKLCKOFC_01205 2.7e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DKLCKOFC_01206 1.8e-201 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DKLCKOFC_01207 4e-284 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DKLCKOFC_01208 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DKLCKOFC_01209 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
DKLCKOFC_01210 2.5e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DKLCKOFC_01211 1.1e-193 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DKLCKOFC_01212 1.4e-89 mraZ K Belongs to the MraZ family
DKLCKOFC_01213 0.0 L DNA helicase
DKLCKOFC_01214 3.2e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DKLCKOFC_01215 1.1e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DKLCKOFC_01216 1.5e-43 M Lysin motif
DKLCKOFC_01217 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DKLCKOFC_01218 1.2e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DKLCKOFC_01219 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
DKLCKOFC_01220 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DKLCKOFC_01221 3.9e-173
DKLCKOFC_01222 2.4e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
DKLCKOFC_01223 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
DKLCKOFC_01224 1.4e-176 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DKLCKOFC_01225 1.1e-57 EGP Major facilitator Superfamily
DKLCKOFC_01226 1.4e-248 S Domain of unknown function (DUF5067)
DKLCKOFC_01227 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
DKLCKOFC_01228 5.4e-283 S Uncharacterized protein conserved in bacteria (DUF2252)
DKLCKOFC_01229 1.7e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
DKLCKOFC_01230 4.8e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DKLCKOFC_01231 5.9e-113
DKLCKOFC_01232 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
DKLCKOFC_01233 1.2e-224 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DKLCKOFC_01234 2.5e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DKLCKOFC_01235 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DKLCKOFC_01236 3.9e-07 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
DKLCKOFC_01238 1.2e-76 yneG S Domain of unknown function (DUF4186)
DKLCKOFC_01239 6.4e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
DKLCKOFC_01240 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
DKLCKOFC_01241 3.4e-202 K WYL domain
DKLCKOFC_01243 0.0 4.2.1.53 S MCRA family
DKLCKOFC_01244 1.6e-46 yhbY J CRS1_YhbY
DKLCKOFC_01245 7.6e-106 S zinc-ribbon domain
DKLCKOFC_01246 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
DKLCKOFC_01247 3e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
DKLCKOFC_01248 6.5e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
DKLCKOFC_01249 9.6e-191 ywqG S Domain of unknown function (DUF1963)
DKLCKOFC_01250 5.3e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DKLCKOFC_01251 4.3e-141 recO L Involved in DNA repair and RecF pathway recombination
DKLCKOFC_01252 4.7e-291 I acetylesterase activity
DKLCKOFC_01253 4.7e-236 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DKLCKOFC_01254 1.2e-222 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DKLCKOFC_01255 3.4e-198 2.7.11.1 NU Tfp pilus assembly protein FimV
DKLCKOFC_01257 4.6e-82
DKLCKOFC_01258 1.2e-145 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
DKLCKOFC_01259 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DKLCKOFC_01260 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
DKLCKOFC_01261 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
DKLCKOFC_01262 1e-188 ftsE D Cell division ATP-binding protein FtsE
DKLCKOFC_01263 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DKLCKOFC_01264 2.6e-138 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
DKLCKOFC_01265 6e-63
DKLCKOFC_01267 9e-178 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DKLCKOFC_01268 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DKLCKOFC_01269 9.7e-90 3.1.21.3 V DivIVA protein
DKLCKOFC_01270 2.1e-42 yggT S YGGT family
DKLCKOFC_01271 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DKLCKOFC_01272 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DKLCKOFC_01273 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DKLCKOFC_01274 7.9e-301 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
DKLCKOFC_01275 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
DKLCKOFC_01276 7.5e-158 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DKLCKOFC_01277 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DKLCKOFC_01278 1.3e-84
DKLCKOFC_01279 6.9e-231 O AAA domain (Cdc48 subfamily)
DKLCKOFC_01280 3e-162 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DKLCKOFC_01281 1.2e-61 S Thiamine-binding protein
DKLCKOFC_01282 5.2e-195 K helix_turn _helix lactose operon repressor
DKLCKOFC_01283 5.7e-47 S Protein of unknown function (DUF3052)
DKLCKOFC_01284 1.5e-152 lon T Belongs to the peptidase S16 family
DKLCKOFC_01285 1.1e-286 S Zincin-like metallopeptidase
DKLCKOFC_01286 4.5e-280 uvrD2 3.6.4.12 L DNA helicase
DKLCKOFC_01287 4.6e-245 mphA S Aminoglycoside phosphotransferase
DKLCKOFC_01288 6.1e-32 S Protein of unknown function (DUF3107)
DKLCKOFC_01289 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
DKLCKOFC_01290 7.6e-115 S Vitamin K epoxide reductase
DKLCKOFC_01291 2.5e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
DKLCKOFC_01292 4.6e-154 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DKLCKOFC_01293 2.3e-168 S Patatin-like phospholipase
DKLCKOFC_01294 4.6e-82 V ABC transporter transmembrane region
DKLCKOFC_01295 2.5e-278 V ABC transporter transmembrane region
DKLCKOFC_01296 0.0 V ABC transporter, ATP-binding protein
DKLCKOFC_01297 1.7e-88 K MarR family
DKLCKOFC_01298 1.2e-54 plyA3 M Parallel beta-helix repeats
DKLCKOFC_01299 8.4e-156 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
DKLCKOFC_01300 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
DKLCKOFC_01301 4.7e-182 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DKLCKOFC_01302 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DKLCKOFC_01303 1e-108 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DKLCKOFC_01304 3e-187 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DKLCKOFC_01305 2.7e-40 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DKLCKOFC_01306 1.9e-289 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
DKLCKOFC_01307 1.8e-240 hom 1.1.1.3 E Homoserine dehydrogenase
DKLCKOFC_01308 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DKLCKOFC_01309 1.1e-280 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
DKLCKOFC_01310 9.9e-67
DKLCKOFC_01311 6.8e-57
DKLCKOFC_01312 8.3e-165 V ATPases associated with a variety of cellular activities
DKLCKOFC_01313 3.3e-256 V Efflux ABC transporter, permease protein
DKLCKOFC_01314 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
DKLCKOFC_01315 1.7e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
DKLCKOFC_01316 0.0 rne 3.1.26.12 J Ribonuclease E/G family
DKLCKOFC_01317 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
DKLCKOFC_01318 3.1e-40 rpmA J Ribosomal L27 protein
DKLCKOFC_01319 4.8e-215 K Psort location Cytoplasmic, score
DKLCKOFC_01320 1.4e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DKLCKOFC_01321 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DKLCKOFC_01322 4e-231 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
DKLCKOFC_01324 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DKLCKOFC_01325 1.8e-116 nusG K Participates in transcription elongation, termination and antitermination
DKLCKOFC_01326 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
DKLCKOFC_01327 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
DKLCKOFC_01328 3.4e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DKLCKOFC_01329 7.5e-202 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DKLCKOFC_01330 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
DKLCKOFC_01331 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKLCKOFC_01332 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DKLCKOFC_01333 4.3e-116
DKLCKOFC_01334 4.5e-172 T Pfam Adenylate and Guanylate cyclase catalytic domain
DKLCKOFC_01335 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
DKLCKOFC_01336 1.1e-79 ssb1 L Single-stranded DNA-binding protein
DKLCKOFC_01337 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DKLCKOFC_01338 6.6e-70 rplI J Binds to the 23S rRNA
DKLCKOFC_01340 1.9e-14 S Parallel beta-helix repeats
DKLCKOFC_01341 6.5e-46 S Parallel beta-helix repeats
DKLCKOFC_01342 1e-69 E Domain of unknown function (DUF5011)
DKLCKOFC_01344 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
DKLCKOFC_01345 3.9e-129 M Protein of unknown function (DUF3152)
DKLCKOFC_01346 5.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
DKLCKOFC_01347 5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DKLCKOFC_01348 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
DKLCKOFC_01349 0.0 inlJ M domain protein
DKLCKOFC_01350 5.6e-281 M LPXTG cell wall anchor motif
DKLCKOFC_01351 7.4e-214 3.4.22.70 M Sortase family
DKLCKOFC_01352 7.5e-95 S Domain of unknown function (DUF4854)
DKLCKOFC_01353 4.2e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
DKLCKOFC_01354 1.7e-27 2.1.1.72 S Protein conserved in bacteria
DKLCKOFC_01355 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DKLCKOFC_01356 1.6e-132 M Mechanosensitive ion channel
DKLCKOFC_01357 5e-119 K Bacterial regulatory proteins, tetR family
DKLCKOFC_01358 4.2e-239 MA20_36090 S Psort location Cytoplasmic, score 8.87
DKLCKOFC_01359 1.2e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
DKLCKOFC_01360 2.6e-68 M Belongs to the glycosyl hydrolase 28 family
DKLCKOFC_01363 2.1e-42 K Transcriptional regulator
DKLCKOFC_01364 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DKLCKOFC_01365 3.5e-07 S Scramblase
DKLCKOFC_01366 2e-28
DKLCKOFC_01371 3.5e-129 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
DKLCKOFC_01372 1.1e-236 K Helix-turn-helix XRE-family like proteins
DKLCKOFC_01373 3.7e-54 relB L RelB antitoxin
DKLCKOFC_01374 2.6e-17 T Toxic component of a toxin-antitoxin (TA) module
DKLCKOFC_01375 2e-132 K helix_turn_helix, mercury resistance
DKLCKOFC_01376 5e-243 yxiO S Vacuole effluxer Atg22 like
DKLCKOFC_01378 6.5e-201 yegV G pfkB family carbohydrate kinase
DKLCKOFC_01379 1.4e-29 rpmB J Ribosomal L28 family
DKLCKOFC_01380 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
DKLCKOFC_01381 4.5e-220 steT E amino acid
DKLCKOFC_01384 0.0
DKLCKOFC_01385 1.1e-244 U Sodium:dicarboxylate symporter family
DKLCKOFC_01386 8.9e-122 rsmD 2.1.1.171 L Conserved hypothetical protein 95
DKLCKOFC_01387 3.1e-107 XK27_02070 S Nitroreductase family
DKLCKOFC_01388 8.9e-83 hsp20 O Hsp20/alpha crystallin family
DKLCKOFC_01389 1.4e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DKLCKOFC_01390 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DKLCKOFC_01391 8.8e-34 CP_0960 S Belongs to the UPF0109 family
DKLCKOFC_01392 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DKLCKOFC_01393 2.5e-294 ydfD EK Alanine-glyoxylate amino-transferase
DKLCKOFC_01394 5.9e-94 argO S LysE type translocator
DKLCKOFC_01395 1.5e-219 S Endonuclease/Exonuclease/phosphatase family
DKLCKOFC_01396 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DKLCKOFC_01397 1.4e-164 P Cation efflux family
DKLCKOFC_01398 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
DKLCKOFC_01399 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
DKLCKOFC_01400 0.0 yjjK S ABC transporter
DKLCKOFC_01401 2e-58 S Protein of unknown function (DUF3039)
DKLCKOFC_01402 2.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DKLCKOFC_01403 3.6e-107
DKLCKOFC_01404 5.1e-113 yceD S Uncharacterized ACR, COG1399
DKLCKOFC_01405 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DKLCKOFC_01406 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DKLCKOFC_01407 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
DKLCKOFC_01408 7.6e-92 ilvN 2.2.1.6 E ACT domain
DKLCKOFC_01410 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DKLCKOFC_01411 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DKLCKOFC_01412 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DKLCKOFC_01413 2.4e-176 S Auxin Efflux Carrier
DKLCKOFC_01416 0.0 pgi 5.3.1.9 G Belongs to the GPI family
DKLCKOFC_01417 1.5e-190
DKLCKOFC_01419 6.9e-201
DKLCKOFC_01421 1.6e-83 mgtC S MgtC family
DKLCKOFC_01422 8.2e-28 mgtC S MgtC family
DKLCKOFC_01423 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
DKLCKOFC_01424 9.7e-34 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
DKLCKOFC_01425 2.4e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
DKLCKOFC_01426 3.5e-277 abcT3 P ATPases associated with a variety of cellular activities
DKLCKOFC_01427 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
DKLCKOFC_01429 1.4e-173 K Putative sugar-binding domain
DKLCKOFC_01430 3.4e-212 gatC G PTS system sugar-specific permease component
DKLCKOFC_01431 8e-293 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
DKLCKOFC_01432 1.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
DKLCKOFC_01433 1.1e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
DKLCKOFC_01434 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DKLCKOFC_01435 6.8e-158 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DKLCKOFC_01436 7.2e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DKLCKOFC_01437 2.9e-207 K helix_turn _helix lactose operon repressor
DKLCKOFC_01438 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DKLCKOFC_01439 1.5e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DKLCKOFC_01440 1.1e-110 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DKLCKOFC_01443 6.1e-172 G Glycosyl hydrolases family 43
DKLCKOFC_01444 9.2e-106 G Glycosyl hydrolases family 43
DKLCKOFC_01445 5.9e-203 K helix_turn _helix lactose operon repressor
DKLCKOFC_01446 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
DKLCKOFC_01447 2.9e-122 L Protein of unknown function (DUF1524)
DKLCKOFC_01448 1.4e-224 mntH P H( )-stimulated, divalent metal cation uptake system
DKLCKOFC_01449 3.9e-250 EGP Major facilitator Superfamily
DKLCKOFC_01450 9.9e-172 L Transposase and inactivated derivatives IS30 family
DKLCKOFC_01451 4.4e-103 K cell envelope-related transcriptional attenuator
DKLCKOFC_01452 3.2e-212
DKLCKOFC_01453 1.3e-179 S G5
DKLCKOFC_01454 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
DKLCKOFC_01455 4.8e-119 F Domain of unknown function (DUF4916)
DKLCKOFC_01456 2.6e-160 mhpC I Alpha/beta hydrolase family
DKLCKOFC_01457 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
DKLCKOFC_01458 0.0 enhA_2 S L,D-transpeptidase catalytic domain
DKLCKOFC_01459 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
DKLCKOFC_01460 9.2e-201 S Uncharacterized conserved protein (DUF2183)
DKLCKOFC_01461 5.1e-27 S Uncharacterized conserved protein (DUF2183)
DKLCKOFC_01462 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
DKLCKOFC_01463 4.5e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DKLCKOFC_01464 9.9e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
DKLCKOFC_01465 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
DKLCKOFC_01466 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DKLCKOFC_01467 1.1e-217 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
DKLCKOFC_01468 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
DKLCKOFC_01469 3.1e-139 glpR K DeoR C terminal sensor domain
DKLCKOFC_01470 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
DKLCKOFC_01471 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
DKLCKOFC_01472 8.6e-243 EGP Sugar (and other) transporter
DKLCKOFC_01473 4.2e-43 gcvR T Belongs to the UPF0237 family
DKLCKOFC_01474 4.7e-252 S UPF0210 protein
DKLCKOFC_01475 2.5e-72
DKLCKOFC_01477 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DKLCKOFC_01478 6.7e-68 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
DKLCKOFC_01479 2.5e-185 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
DKLCKOFC_01480 7.6e-107
DKLCKOFC_01481 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DKLCKOFC_01482 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DKLCKOFC_01483 7.2e-95 T Forkhead associated domain
DKLCKOFC_01484 2.8e-68 B Belongs to the OprB family
DKLCKOFC_01485 3.7e-165 3.1.3.16 T Sigma factor PP2C-like phosphatases
DKLCKOFC_01486 0.0 E Transglutaminase-like superfamily
DKLCKOFC_01487 5.7e-231 S Protein of unknown function DUF58
DKLCKOFC_01488 1.8e-232 S ATPase family associated with various cellular activities (AAA)
DKLCKOFC_01489 0.0 S Fibronectin type 3 domain
DKLCKOFC_01490 3.4e-269 KLT Protein tyrosine kinase
DKLCKOFC_01491 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
DKLCKOFC_01492 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
DKLCKOFC_01493 3.4e-147 K -acetyltransferase
DKLCKOFC_01494 3.8e-249 G Major Facilitator Superfamily
DKLCKOFC_01495 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
DKLCKOFC_01496 6.4e-24 relB L RelB antitoxin
DKLCKOFC_01497 5.5e-35 L Transposase
DKLCKOFC_01498 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DKLCKOFC_01499 2.8e-45 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKLCKOFC_01500 2.2e-102 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKLCKOFC_01501 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DKLCKOFC_01502 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
DKLCKOFC_01503 4.8e-291 O Subtilase family
DKLCKOFC_01504 2.1e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DKLCKOFC_01505 8.8e-124 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DKLCKOFC_01506 1.4e-270 S zinc finger
DKLCKOFC_01507 4.1e-105 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
DKLCKOFC_01508 2.9e-229 aspB E Aminotransferase class-V
DKLCKOFC_01509 9e-157 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DKLCKOFC_01510 3.5e-132 tmp1 S Domain of unknown function (DUF4391)
DKLCKOFC_01511 4.4e-149 moeB 2.7.7.80 H ThiF family
DKLCKOFC_01512 1.3e-254 cdr OP Sulfurtransferase TusA
DKLCKOFC_01513 3.1e-181 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DKLCKOFC_01516 9.6e-203 S Endonuclease/Exonuclease/phosphatase family
DKLCKOFC_01517 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DKLCKOFC_01518 3.6e-271 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DKLCKOFC_01519 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
DKLCKOFC_01520 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DKLCKOFC_01522 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
DKLCKOFC_01523 1.2e-166
DKLCKOFC_01524 1.9e-259 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
DKLCKOFC_01525 1.7e-306 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
DKLCKOFC_01526 4e-144 cobB2 K Sir2 family
DKLCKOFC_01527 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
DKLCKOFC_01528 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DKLCKOFC_01529 1.2e-145 ypfH S Phospholipase/Carboxylesterase
DKLCKOFC_01530 0.0 yjcE P Sodium/hydrogen exchanger family
DKLCKOFC_01531 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
DKLCKOFC_01532 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
DKLCKOFC_01533 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
DKLCKOFC_01535 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKLCKOFC_01536 1e-270 KLT Domain of unknown function (DUF4032)
DKLCKOFC_01537 5.4e-153
DKLCKOFC_01538 4.5e-180 3.4.22.70 M Sortase family
DKLCKOFC_01539 1.4e-250 M LPXTG-motif cell wall anchor domain protein
DKLCKOFC_01540 0.0 S LPXTG-motif cell wall anchor domain protein
DKLCKOFC_01541 0.0 S LPXTG-motif cell wall anchor domain protein
DKLCKOFC_01542 2.3e-101 L Helix-turn-helix domain
DKLCKOFC_01543 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
DKLCKOFC_01544 1.3e-173 K Psort location Cytoplasmic, score
DKLCKOFC_01545 0.0 KLT Protein tyrosine kinase
DKLCKOFC_01546 7.1e-150 O Thioredoxin
DKLCKOFC_01548 1.2e-211 S G5
DKLCKOFC_01549 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DKLCKOFC_01550 2.1e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DKLCKOFC_01551 6.7e-113 S LytR cell envelope-related transcriptional attenuator
DKLCKOFC_01552 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
DKLCKOFC_01553 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
DKLCKOFC_01554 0.0 M Conserved repeat domain
DKLCKOFC_01555 0.0 murJ KLT MviN-like protein
DKLCKOFC_01556 2.6e-203 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DKLCKOFC_01557 1.2e-242 parB K Belongs to the ParB family
DKLCKOFC_01558 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
DKLCKOFC_01559 1.3e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DKLCKOFC_01560 8.6e-93 jag S Putative single-stranded nucleic acids-binding domain
DKLCKOFC_01561 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
DKLCKOFC_01562 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DKLCKOFC_01563 4.1e-300 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DKLCKOFC_01564 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DKLCKOFC_01565 2e-239 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DKLCKOFC_01566 2e-87 S Protein of unknown function (DUF721)
DKLCKOFC_01567 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DKLCKOFC_01568 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DKLCKOFC_01569 4.6e-73 S Transmembrane domain of unknown function (DUF3566)
DKLCKOFC_01570 2.6e-15 abfA1 3.2.1.55 GH51 G arabinose metabolic process
DKLCKOFC_01572 4.6e-187 G Glycosyl hydrolases family 43
DKLCKOFC_01573 1.6e-187 K Periplasmic binding protein domain
DKLCKOFC_01574 2.6e-227 I Serine aminopeptidase, S33
DKLCKOFC_01575 8.3e-09 K helix_turn _helix lactose operon repressor
DKLCKOFC_01577 1.9e-24 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DKLCKOFC_01578 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DKLCKOFC_01579 2.5e-124 gntR K FCD
DKLCKOFC_01580 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DKLCKOFC_01581 0.0 3.2.1.55 GH51 G arabinose metabolic process
DKLCKOFC_01584 0.0 G Glycosyl hydrolase family 20, domain 2
DKLCKOFC_01585 3.9e-190 K helix_turn _helix lactose operon repressor
DKLCKOFC_01586 4.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DKLCKOFC_01587 9.6e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
DKLCKOFC_01588 2.8e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
DKLCKOFC_01589 1.9e-135 S Protein of unknown function DUF45
DKLCKOFC_01590 1.9e-83 dps P Belongs to the Dps family
DKLCKOFC_01591 1.3e-188 yddG EG EamA-like transporter family
DKLCKOFC_01592 3.6e-241 ytfL P Transporter associated domain
DKLCKOFC_01593 1.1e-95 K helix_turn _helix lactose operon repressor
DKLCKOFC_01594 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
DKLCKOFC_01595 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
DKLCKOFC_01596 0.0 trxB1 1.8.1.9 C Thioredoxin domain
DKLCKOFC_01597 1.3e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DKLCKOFC_01598 4.3e-239 yhjX EGP Major facilitator Superfamily
DKLCKOFC_01599 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DKLCKOFC_01600 0.0 yjjP S Threonine/Serine exporter, ThrE
DKLCKOFC_01601 1.4e-177 S Amidohydrolase family
DKLCKOFC_01602 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DKLCKOFC_01603 3.2e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DKLCKOFC_01604 1e-47 S Protein of unknown function (DUF3073)
DKLCKOFC_01605 2.7e-111 T protein histidine kinase activity
DKLCKOFC_01606 1e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DKLCKOFC_01607 1.1e-24 I transferase activity, transferring acyl groups other than amino-acyl groups
DKLCKOFC_01608 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
DKLCKOFC_01609 6.5e-167 rfbJ M Glycosyl transferase family 2
DKLCKOFC_01610 2.8e-72 L Transposase
DKLCKOFC_01611 1.3e-207 S Acyltransferase family
DKLCKOFC_01612 4.3e-298
DKLCKOFC_01613 0.0 wbbM M Glycosyl transferase family 8
DKLCKOFC_01614 2.6e-174 ppm1 GT2 M Glycosyl transferase, family 2
DKLCKOFC_01615 0.0 M Belongs to the glycosyl hydrolase 43 family
DKLCKOFC_01616 9.8e-127 L IstB-like ATP binding protein
DKLCKOFC_01617 5.7e-254 L Transposase
DKLCKOFC_01618 2.1e-142 M Putative cell wall binding repeat 2
DKLCKOFC_01619 5.6e-121 L Protein of unknown function (DUF1524)
DKLCKOFC_01620 0.0 2.1.1.72, 3.1.4.46, 3.2.1.1 GH13 M hydrolase, family 25
DKLCKOFC_01621 1.8e-240 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
DKLCKOFC_01622 2.5e-139 rgpC U Transport permease protein
DKLCKOFC_01623 0.0 wbbM M Glycosyl transferase family 8
DKLCKOFC_01624 3.2e-215 1.1.1.22 M UDP binding domain
DKLCKOFC_01625 4.4e-15 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DKLCKOFC_01626 1.2e-153 K Transposase IS116 IS110 IS902
DKLCKOFC_01627 7.3e-119 tnp7109-21 L Integrase core domain
DKLCKOFC_01628 2.6e-43 L Transposase
DKLCKOFC_01629 3.3e-09
DKLCKOFC_01631 9.5e-45 L Transposase DDE domain
DKLCKOFC_01632 2.7e-156 bglA 3.2.1.21 G Glycosyl hydrolase family 1
DKLCKOFC_01633 3.8e-194 L Transposase, Mutator family
DKLCKOFC_01634 2.6e-227 glf 5.4.99.9 M UDP-galactopyranose mutase
DKLCKOFC_01635 2.6e-43 3.6.1.13 L NUDIX domain
DKLCKOFC_01636 1.5e-101
DKLCKOFC_01637 4e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DKLCKOFC_01638 1.5e-215 G Transmembrane secretion effector
DKLCKOFC_01639 2e-118 K Bacterial regulatory proteins, tetR family
DKLCKOFC_01640 3.5e-12
DKLCKOFC_01641 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
DKLCKOFC_01642 1.1e-42 tnp7109-21 L Integrase core domain
DKLCKOFC_01643 2.5e-52 L IstB-like ATP binding protein
DKLCKOFC_01644 8.7e-46 L Transposase
DKLCKOFC_01645 2e-73 I Sterol carrier protein
DKLCKOFC_01646 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DKLCKOFC_01647 3.4e-35
DKLCKOFC_01648 1.9e-144 gluP 3.4.21.105 S Rhomboid family
DKLCKOFC_01649 1.3e-120 L HTH-like domain
DKLCKOFC_01650 1.4e-256 L ribosomal rna small subunit methyltransferase
DKLCKOFC_01651 2.6e-71 crgA D Involved in cell division
DKLCKOFC_01652 7.9e-143 S Bacterial protein of unknown function (DUF881)
DKLCKOFC_01653 1.8e-231 srtA 3.4.22.70 M Sortase family
DKLCKOFC_01654 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
DKLCKOFC_01655 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
DKLCKOFC_01656 2e-183 T Protein tyrosine kinase
DKLCKOFC_01657 3.7e-263 pbpA M penicillin-binding protein
DKLCKOFC_01658 2.8e-266 rodA D Belongs to the SEDS family
DKLCKOFC_01659 4.8e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
DKLCKOFC_01660 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
DKLCKOFC_01661 1e-130 fhaA T Protein of unknown function (DUF2662)
DKLCKOFC_01662 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
DKLCKOFC_01663 0.0 pip S YhgE Pip domain protein
DKLCKOFC_01664 1e-166 pip S YhgE Pip domain protein
DKLCKOFC_01665 1.8e-162 pip S YhgE Pip domain protein
DKLCKOFC_01666 1.9e-205 pldB 3.1.1.5 I Serine aminopeptidase, S33
DKLCKOFC_01667 6.2e-166 yicL EG EamA-like transporter family
DKLCKOFC_01668 2e-103
DKLCKOFC_01670 5.4e-197 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DKLCKOFC_01672 0.0 KL Domain of unknown function (DUF3427)
DKLCKOFC_01673 1.3e-90 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
DKLCKOFC_01674 3.3e-41 D DivIVA domain protein
DKLCKOFC_01675 9.3e-53 ybjQ S Putative heavy-metal-binding
DKLCKOFC_01676 3.8e-156 I Serine aminopeptidase, S33
DKLCKOFC_01677 7e-86 yjcF Q Acetyltransferase (GNAT) domain
DKLCKOFC_01678 3.4e-32 L transposase activity
DKLCKOFC_01679 1.5e-53 tnp7109-21 L Integrase core domain
DKLCKOFC_01680 5.6e-42 tnp7109-21 L Integrase core domain
DKLCKOFC_01681 6.4e-16 L Phage integrase family
DKLCKOFC_01682 4.2e-08
DKLCKOFC_01684 3.2e-79 L HindVP restriction endonuclease
DKLCKOFC_01685 7e-116 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
DKLCKOFC_01686 5.2e-33
DKLCKOFC_01687 1.1e-36 CP_0155 3.5.1.28 M LysM domain
DKLCKOFC_01688 2.6e-57 M Glycosyl hydrolases family 25
DKLCKOFC_01689 3.9e-15 2.7.7.7 L Transposase, Mutator family
DKLCKOFC_01691 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DKLCKOFC_01692 3.9e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
DKLCKOFC_01693 0.0 cadA P E1-E2 ATPase
DKLCKOFC_01694 2.5e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
DKLCKOFC_01695 3.9e-173 htpX O Belongs to the peptidase M48B family
DKLCKOFC_01697 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DKLCKOFC_01698 1.9e-42 S Bacterial mobilisation protein (MobC)
DKLCKOFC_01699 2.3e-127 S Domain of unknown function (DUF4417)
DKLCKOFC_01701 1.9e-61
DKLCKOFC_01702 6.8e-65
DKLCKOFC_01703 3.9e-50 E IrrE N-terminal-like domain
DKLCKOFC_01704 2e-12 E IrrE N-terminal-like domain
DKLCKOFC_01705 4.9e-57 K Cro/C1-type HTH DNA-binding domain
DKLCKOFC_01706 2.5e-247 3.5.1.104 G Polysaccharide deacetylase
DKLCKOFC_01707 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
DKLCKOFC_01708 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DKLCKOFC_01709 3.7e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DKLCKOFC_01710 1.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DKLCKOFC_01711 8.4e-193 K helix_turn _helix lactose operon repressor
DKLCKOFC_01712 4.8e-78 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
DKLCKOFC_01713 7e-298 scrT G Transporter major facilitator family protein
DKLCKOFC_01714 5e-254 yhjE EGP Sugar (and other) transporter
DKLCKOFC_01715 1.1e-140 yplQ S Haemolysin-III related
DKLCKOFC_01716 4.7e-285 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DKLCKOFC_01717 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DKLCKOFC_01718 0.0 D FtsK/SpoIIIE family
DKLCKOFC_01719 2.4e-270 K Cell envelope-related transcriptional attenuator domain
DKLCKOFC_01720 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DKLCKOFC_01721 0.0 S Glycosyl transferase, family 2
DKLCKOFC_01722 2.2e-266
DKLCKOFC_01723 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
DKLCKOFC_01724 5e-156 cof 5.2.1.8 T Eukaryotic phosphomannomutase
DKLCKOFC_01725 9.2e-130 ctsW S Phosphoribosyl transferase domain
DKLCKOFC_01726 8.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
DKLCKOFC_01727 1.1e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DKLCKOFC_01728 1.9e-127 T Response regulator receiver domain protein
DKLCKOFC_01729 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DKLCKOFC_01730 5.1e-102 carD K CarD-like/TRCF domain
DKLCKOFC_01731 4.2e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DKLCKOFC_01732 4.3e-139 znuB U ABC 3 transport family
DKLCKOFC_01733 1.8e-164 znuC P ATPases associated with a variety of cellular activities
DKLCKOFC_01734 9.6e-173 P Zinc-uptake complex component A periplasmic
DKLCKOFC_01735 2e-163 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DKLCKOFC_01736 6.8e-241 rpsA J Ribosomal protein S1
DKLCKOFC_01737 4.5e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DKLCKOFC_01738 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DKLCKOFC_01739 2.3e-102 terC P Integral membrane protein, TerC family
DKLCKOFC_01740 1.9e-272 pyk 2.7.1.40 G Pyruvate kinase
DKLCKOFC_01741 3.3e-109 aspA 3.6.1.13 L NUDIX domain
DKLCKOFC_01743 9.2e-120 pdtaR T Response regulator receiver domain protein
DKLCKOFC_01744 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DKLCKOFC_01745 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
DKLCKOFC_01746 1.2e-118 3.6.1.13 L NUDIX domain
DKLCKOFC_01747 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DKLCKOFC_01748 7.4e-217 ykiI
DKLCKOFC_01750 2.5e-14
DKLCKOFC_01751 5.6e-43 yafP 5.3.1.16 K Acetyltransferase (GNAT) domain
DKLCKOFC_01752 4.8e-24 yafP 5.3.1.16 K Acetyltransferase (GNAT) domain
DKLCKOFC_01753 2e-16 U Major Facilitator Superfamily
DKLCKOFC_01754 1.6e-73 K helix_turn_helix multiple antibiotic resistance protein
DKLCKOFC_01755 2.2e-72 K helix_turn_helix, mercury resistance
DKLCKOFC_01756 2.6e-163 1.1.1.346 S Aldo/keto reductase family
DKLCKOFC_01757 1.2e-100 3.5.1.124 S DJ-1/PfpI family
DKLCKOFC_01758 9.7e-129
DKLCKOFC_01760 2.9e-108 3.4.13.21 E Peptidase family S51
DKLCKOFC_01761 1.4e-275 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DKLCKOFC_01762 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DKLCKOFC_01763 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DKLCKOFC_01764 6.8e-71 XK27_07020 S Domain of unknown function (DUF1846)
DKLCKOFC_01765 2.2e-80
DKLCKOFC_01766 4.2e-09 S Domain of unknown function (DUF4339)
DKLCKOFC_01767 8.7e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DKLCKOFC_01768 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
DKLCKOFC_01769 3.4e-189 pit P Phosphate transporter family
DKLCKOFC_01770 1.1e-115 MA20_27875 P Protein of unknown function DUF47
DKLCKOFC_01771 3.1e-119 K helix_turn_helix, Lux Regulon
DKLCKOFC_01772 7.8e-233 T Histidine kinase
DKLCKOFC_01773 9.9e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
DKLCKOFC_01774 2.9e-179 V ATPases associated with a variety of cellular activities
DKLCKOFC_01775 1.8e-226 V ABC-2 family transporter protein
DKLCKOFC_01776 3.4e-253 V ABC-2 family transporter protein
DKLCKOFC_01777 2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DKLCKOFC_01778 4.3e-205 L Transposase and inactivated derivatives IS30 family
DKLCKOFC_01780 1.2e-85
DKLCKOFC_01781 1.2e-64 D MobA/MobL family
DKLCKOFC_01782 8.6e-48 L Transposase
DKLCKOFC_01783 5.9e-182 tnp7109-21 L Integrase core domain
DKLCKOFC_01784 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
DKLCKOFC_01785 9e-40
DKLCKOFC_01786 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
DKLCKOFC_01788 8.1e-47 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DKLCKOFC_01790 2e-239 pbuX F Permease family
DKLCKOFC_01791 1.9e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DKLCKOFC_01792 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
DKLCKOFC_01793 0.0 pcrA 3.6.4.12 L DNA helicase
DKLCKOFC_01794 8.2e-64 S Domain of unknown function (DUF4418)
DKLCKOFC_01795 9.4e-212 V FtsX-like permease family
DKLCKOFC_01796 1.9e-128 lolD V ABC transporter
DKLCKOFC_01797 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DKLCKOFC_01798 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
DKLCKOFC_01799 6.5e-136 pgm3 G Phosphoglycerate mutase family
DKLCKOFC_01800 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
DKLCKOFC_01801 1.1e-36
DKLCKOFC_01802 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DKLCKOFC_01803 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DKLCKOFC_01804 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DKLCKOFC_01805 6.3e-47 3.4.23.43 S Type IV leader peptidase family
DKLCKOFC_01806 1.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DKLCKOFC_01807 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DKLCKOFC_01808 5.9e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
DKLCKOFC_01809 1.9e-75
DKLCKOFC_01810 1.7e-120 K helix_turn_helix, Lux Regulon
DKLCKOFC_01811 2.6e-07 3.4.22.70 M Sortase family
DKLCKOFC_01812 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DKLCKOFC_01813 3.6e-290 sufB O FeS assembly protein SufB
DKLCKOFC_01814 1.4e-234 sufD O FeS assembly protein SufD
DKLCKOFC_01815 2.4e-144 sufC O FeS assembly ATPase SufC
DKLCKOFC_01816 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DKLCKOFC_01817 2.6e-100 iscU C SUF system FeS assembly protein, NifU family
DKLCKOFC_01818 1.2e-108 yitW S Iron-sulfur cluster assembly protein
DKLCKOFC_01819 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DKLCKOFC_01820 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
DKLCKOFC_01822 4.7e-83 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DKLCKOFC_01823 4.9e-35 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DKLCKOFC_01824 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
DKLCKOFC_01825 3.4e-197 phoH T PhoH-like protein
DKLCKOFC_01826 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DKLCKOFC_01827 2.4e-251 corC S CBS domain
DKLCKOFC_01828 1.5e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DKLCKOFC_01829 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DKLCKOFC_01830 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
DKLCKOFC_01831 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
DKLCKOFC_01832 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DKLCKOFC_01833 1.8e-189 S alpha beta
DKLCKOFC_01834 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DKLCKOFC_01835 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
DKLCKOFC_01836 1.8e-46 S phosphoesterase or phosphohydrolase
DKLCKOFC_01837 2.7e-99 3.1.4.37 T RNA ligase
DKLCKOFC_01838 1.2e-135 S UPF0126 domain
DKLCKOFC_01839 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
DKLCKOFC_01840 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DKLCKOFC_01841 1.5e-245 hemN H Involved in the biosynthesis of porphyrin-containing compound
DKLCKOFC_01842 3.4e-12 S Membrane
DKLCKOFC_01843 1.4e-287 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
DKLCKOFC_01844 0.0 tetP J Elongation factor G, domain IV
DKLCKOFC_01845 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
DKLCKOFC_01846 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DKLCKOFC_01847 3.6e-82
DKLCKOFC_01848 1.1e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
DKLCKOFC_01849 1.6e-182 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
DKLCKOFC_01850 1.5e-158 ybeM S Carbon-nitrogen hydrolase
DKLCKOFC_01851 1.3e-113 S Sel1-like repeats.
DKLCKOFC_01852 1.2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DKLCKOFC_01853 1.7e-61 S Short C-terminal domain
DKLCKOFC_01854 9.3e-181 L Transposase
DKLCKOFC_01855 1.6e-28
DKLCKOFC_01856 2.3e-31 XK26_04895
DKLCKOFC_01857 5.1e-22 XK26_04895
DKLCKOFC_01858 0.0 KL Type III restriction enzyme res subunit
DKLCKOFC_01859 1.9e-38 L Eco57I restriction-modification methylase
DKLCKOFC_01860 6.9e-56 L Eco57I restriction-modification methylase
DKLCKOFC_01861 2.8e-182 3.1.21.4 V Type III restriction enzyme res subunit
DKLCKOFC_01862 2.5e-56 S SIR2-like domain
DKLCKOFC_01863 1.2e-88 S AAA-like domain
DKLCKOFC_01864 1.1e-128 S AAA-like domain
DKLCKOFC_01865 0.0 S Protein of unknown function DUF262
DKLCKOFC_01866 1.1e-29
DKLCKOFC_01867 4e-71 rarD 3.4.17.13 E Rard protein
DKLCKOFC_01868 1.4e-23 rarD S EamA-like transporter family
DKLCKOFC_01869 3e-178 I alpha/beta hydrolase fold
DKLCKOFC_01870 7.4e-208 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DKLCKOFC_01871 2e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
DKLCKOFC_01872 3.9e-242 int L Phage integrase, N-terminal SAM-like domain
DKLCKOFC_01873 5.1e-45 E IrrE N-terminal-like domain
DKLCKOFC_01874 6e-16
DKLCKOFC_01875 3.8e-50
DKLCKOFC_01876 2.5e-104 S Virulence protein RhuM family
DKLCKOFC_01877 1.2e-54
DKLCKOFC_01878 1.9e-34
DKLCKOFC_01879 8.2e-53
DKLCKOFC_01880 3.3e-22
DKLCKOFC_01881 2e-122 K BRO family, N-terminal domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)