ORF_ID e_value Gene_name EC_number CAZy COGs Description
HAPJLFFH_00001 1.2e-299 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAPJLFFH_00002 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HAPJLFFH_00003 1.3e-227 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAPJLFFH_00004 3.2e-93 S Protein of unknown function (DUF721)
HAPJLFFH_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAPJLFFH_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAPJLFFH_00007 1.2e-73 S Transmembrane domain of unknown function (DUF3566)
HAPJLFFH_00008 1.3e-14 abfA1 3.2.1.55 GH51 G arabinose metabolic process
HAPJLFFH_00009 1.2e-06 S Parallel beta-helix repeats
HAPJLFFH_00010 1e-186 G Glycosyl hydrolases family 43
HAPJLFFH_00011 1.8e-186 K Periplasmic binding protein domain
HAPJLFFH_00012 1.5e-227 I Serine aminopeptidase, S33
HAPJLFFH_00013 7.4e-08 K helix_turn _helix lactose operon repressor
HAPJLFFH_00014 9.6e-42 S Protein of unknown function (DUF2442)
HAPJLFFH_00015 3.4e-18 S Domain of unknown function (DUF4160)
HAPJLFFH_00016 4.2e-14 K Helix-turn-helix domain
HAPJLFFH_00019 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HAPJLFFH_00020 6.2e-42 gntR K FCD
HAPJLFFH_00021 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HAPJLFFH_00022 0.0 3.2.1.55 GH51 G arabinose metabolic process
HAPJLFFH_00025 0.0 G Glycosyl hydrolase family 20, domain 2
HAPJLFFH_00026 1.4e-187 K helix_turn _helix lactose operon repressor
HAPJLFFH_00027 3.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HAPJLFFH_00028 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HAPJLFFH_00029 5.2e-252 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HAPJLFFH_00030 3.5e-137 S Protein of unknown function DUF45
HAPJLFFH_00031 1.9e-83 dps P Belongs to the Dps family
HAPJLFFH_00032 1.3e-188 yddG EG EamA-like transporter family
HAPJLFFH_00033 1.2e-241 ytfL P Transporter associated domain
HAPJLFFH_00034 1.8e-94 K helix_turn _helix lactose operon repressor
HAPJLFFH_00035 5.8e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HAPJLFFH_00036 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HAPJLFFH_00037 0.0 trxB1 1.8.1.9 C Thioredoxin domain
HAPJLFFH_00038 5e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HAPJLFFH_00039 2.8e-238 yhjX EGP Major facilitator Superfamily
HAPJLFFH_00040 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HAPJLFFH_00041 0.0 yjjP S Threonine/Serine exporter, ThrE
HAPJLFFH_00042 1.4e-177 S Amidohydrolase family
HAPJLFFH_00043 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAPJLFFH_00044 6.5e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAPJLFFH_00045 1e-47 S Protein of unknown function (DUF3073)
HAPJLFFH_00046 1.6e-88 K LytTr DNA-binding domain
HAPJLFFH_00047 2e-106 T protein histidine kinase activity
HAPJLFFH_00048 2e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HAPJLFFH_00049 1e-28 I transferase activity, transferring acyl groups other than amino-acyl groups
HAPJLFFH_00050 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HAPJLFFH_00051 3e-173 rfbJ M Glycosyl transferase family 2
HAPJLFFH_00052 0.0
HAPJLFFH_00053 9.7e-202 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HAPJLFFH_00054 0.0 3.6.4.12 K Putative DNA-binding domain
HAPJLFFH_00055 1.6e-290 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HAPJLFFH_00056 4.4e-45 L Transposase DDE domain
HAPJLFFH_00057 1.7e-16 L Transposase
HAPJLFFH_00058 4.1e-144 L IstB-like ATP binding protein
HAPJLFFH_00059 5.8e-296 L PFAM Integrase catalytic
HAPJLFFH_00060 2e-105 L transposase activity
HAPJLFFH_00061 9.7e-107 L PFAM Integrase catalytic
HAPJLFFH_00062 2.5e-155 L Transposase, Mutator family
HAPJLFFH_00063 1.2e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HAPJLFFH_00064 8.7e-131 rgpC U Transport permease protein
HAPJLFFH_00065 1.3e-208 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
HAPJLFFH_00066 2.5e-294 S Tetratricopeptide repeat
HAPJLFFH_00067 0.0 rgpF M Rhamnan synthesis protein F
HAPJLFFH_00068 4.9e-193 M Glycosyltransferase like family 2
HAPJLFFH_00069 3.1e-108 L Transposase and inactivated derivatives IS30 family
HAPJLFFH_00070 4.1e-144 L IstB-like ATP binding protein
HAPJLFFH_00071 5.8e-296 L PFAM Integrase catalytic
HAPJLFFH_00072 2.9e-66 L Transposase and inactivated derivatives IS30 family
HAPJLFFH_00073 8.8e-259 S Domain of unknown function (DUF4143)
HAPJLFFH_00074 1.4e-57 yccF S Inner membrane component domain
HAPJLFFH_00075 4.5e-12
HAPJLFFH_00076 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
HAPJLFFH_00077 1.1e-42 tnp7109-21 L Integrase core domain
HAPJLFFH_00078 6.9e-44 L IstB-like ATP binding protein
HAPJLFFH_00079 7.4e-45 L Transposase
HAPJLFFH_00080 9.8e-19 V ATPases associated with a variety of cellular activities
HAPJLFFH_00081 4.4e-73 I Sterol carrier protein
HAPJLFFH_00082 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HAPJLFFH_00083 3.4e-35
HAPJLFFH_00084 1.9e-144 gluP 3.4.21.105 S Rhomboid family
HAPJLFFH_00085 1.3e-120 L HTH-like domain
HAPJLFFH_00086 1.4e-256 L ribosomal rna small subunit methyltransferase
HAPJLFFH_00087 2.6e-71 crgA D Involved in cell division
HAPJLFFH_00088 7.9e-143 S Bacterial protein of unknown function (DUF881)
HAPJLFFH_00089 3.1e-231 srtA 3.4.22.70 M Sortase family
HAPJLFFH_00090 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HAPJLFFH_00091 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
HAPJLFFH_00092 2e-183 T Protein tyrosine kinase
HAPJLFFH_00093 2.8e-263 pbpA M penicillin-binding protein
HAPJLFFH_00094 2.8e-266 rodA D Belongs to the SEDS family
HAPJLFFH_00095 9.7e-260 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HAPJLFFH_00096 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HAPJLFFH_00097 1e-130 fhaA T Protein of unknown function (DUF2662)
HAPJLFFH_00098 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HAPJLFFH_00099 0.0 pip S YhgE Pip domain protein
HAPJLFFH_00100 0.0 pip S YhgE Pip domain protein
HAPJLFFH_00101 8.7e-206 pldB 3.1.1.5 I Serine aminopeptidase, S33
HAPJLFFH_00102 6e-169 yicL EG EamA-like transporter family
HAPJLFFH_00103 2e-103
HAPJLFFH_00105 6e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAPJLFFH_00107 0.0 KL Domain of unknown function (DUF3427)
HAPJLFFH_00108 2.5e-89 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HAPJLFFH_00109 5.7e-36 D DivIVA domain protein
HAPJLFFH_00110 9.3e-53 ybjQ S Putative heavy-metal-binding
HAPJLFFH_00111 4.2e-155 I Serine aminopeptidase, S33
HAPJLFFH_00112 6.3e-87 yjcF Q Acetyltransferase (GNAT) domain
HAPJLFFH_00114 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HAPJLFFH_00115 3.9e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HAPJLFFH_00116 0.0 cadA P E1-E2 ATPase
HAPJLFFH_00117 2.5e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HAPJLFFH_00118 2.9e-168 htpX O Belongs to the peptidase M48B family
HAPJLFFH_00120 3.1e-245 3.5.1.104 G Polysaccharide deacetylase
HAPJLFFH_00121 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HAPJLFFH_00122 3e-68 D AAA domain, putative AbiEii toxin, Type IV TA system
HAPJLFFH_00123 3.9e-10 V TIGR02646 family
HAPJLFFH_00124 8.3e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAPJLFFH_00125 8.7e-165 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAPJLFFH_00126 1.1e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAPJLFFH_00127 7.1e-200 K helix_turn _helix lactose operon repressor
HAPJLFFH_00128 1.3e-75 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HAPJLFFH_00129 1.6e-297 scrT G Transporter major facilitator family protein
HAPJLFFH_00130 5e-254 yhjE EGP Sugar (and other) transporter
HAPJLFFH_00131 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAPJLFFH_00132 9e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAPJLFFH_00133 1.2e-183 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
HAPJLFFH_00135 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HAPJLFFH_00136 3.3e-275 aroP E aromatic amino acid transport protein AroP K03293
HAPJLFFH_00137 7e-101 K Transcriptional regulator C-terminal region
HAPJLFFH_00138 2.6e-129 V ABC transporter
HAPJLFFH_00139 0.0 V FtsX-like permease family
HAPJLFFH_00140 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAPJLFFH_00141 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HAPJLFFH_00142 9.9e-39 E ABC transporter
HAPJLFFH_00143 7.6e-100 bcp 1.11.1.15 O Redoxin
HAPJLFFH_00144 2.1e-150 S Virulence factor BrkB
HAPJLFFH_00145 2.1e-41 XAC3035 O Glutaredoxin
HAPJLFFH_00146 7.6e-87
HAPJLFFH_00147 9e-36
HAPJLFFH_00148 1.9e-25
HAPJLFFH_00149 1.4e-13
HAPJLFFH_00150 5.6e-272
HAPJLFFH_00151 1.4e-297 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
HAPJLFFH_00153 1.8e-218 3.1.21.3 V Type I restriction modification DNA specificity domain
HAPJLFFH_00154 1.2e-174 V Abi-like protein
HAPJLFFH_00155 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HAPJLFFH_00156 1.4e-59 S Bacterial mobilisation protein (MobC)
HAPJLFFH_00157 0.0 ltrBE1 U Relaxase/Mobilisation nuclease domain
HAPJLFFH_00158 4.7e-105
HAPJLFFH_00161 4.4e-259 L Phage integrase, N-terminal SAM-like domain
HAPJLFFH_00163 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
HAPJLFFH_00164 8.1e-98 M Belongs to the glycosyl hydrolase 30 family
HAPJLFFH_00165 3.3e-191 1.1.1.65 C Aldo/keto reductase family
HAPJLFFH_00166 2.9e-93 ydgJ K helix_turn_helix multiple antibiotic resistance protein
HAPJLFFH_00167 0.0 lmrA1 V ABC transporter, ATP-binding protein
HAPJLFFH_00168 0.0 lmrA2 V ABC transporter transmembrane region
HAPJLFFH_00169 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
HAPJLFFH_00170 1.3e-107 S Phosphatidylethanolamine-binding protein
HAPJLFFH_00171 0.0 pepD E Peptidase family C69
HAPJLFFH_00172 6.2e-288 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HAPJLFFH_00173 1.3e-62 S Macrophage migration inhibitory factor (MIF)
HAPJLFFH_00174 6.8e-98 S GtrA-like protein
HAPJLFFH_00175 1.1e-262 EGP Major facilitator Superfamily
HAPJLFFH_00176 1.1e-124 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HAPJLFFH_00177 1.2e-142
HAPJLFFH_00178 4.9e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HAPJLFFH_00179 8.6e-201 P NMT1/THI5 like
HAPJLFFH_00180 4.9e-122 S HAD hydrolase, family IA, variant 3
HAPJLFFH_00182 1.1e-275 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAPJLFFH_00183 3.1e-95 S Domain of unknown function (DUF4143)
HAPJLFFH_00184 5.7e-43 S Domain of unknown function (DUF4143)
HAPJLFFH_00185 1.8e-26 S Polyketide cyclase / dehydrase and lipid transport
HAPJLFFH_00188 4.4e-252 S Calcineurin-like phosphoesterase
HAPJLFFH_00189 2.2e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HAPJLFFH_00190 8.4e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAPJLFFH_00191 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAPJLFFH_00192 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
HAPJLFFH_00194 5.4e-182 S CAAX protease self-immunity
HAPJLFFH_00195 4.7e-221 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
HAPJLFFH_00196 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAPJLFFH_00197 3.3e-226 G Transmembrane secretion effector
HAPJLFFH_00198 7.3e-132 K Bacterial regulatory proteins, tetR family
HAPJLFFH_00199 3.5e-126
HAPJLFFH_00200 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAPJLFFH_00201 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HAPJLFFH_00202 6.3e-166 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HAPJLFFH_00203 5.1e-185
HAPJLFFH_00204 7.9e-180
HAPJLFFH_00205 1.3e-163 trxA2 O Tetratricopeptide repeat
HAPJLFFH_00206 1.4e-118 cyaA 4.6.1.1 S CYTH
HAPJLFFH_00209 1.8e-184 K Bacterial regulatory proteins, lacI family
HAPJLFFH_00210 1.6e-17 4.2.1.68 M carboxylic acid catabolic process
HAPJLFFH_00211 9.5e-41 4.2.1.68 M Enolase C-terminal domain-like
HAPJLFFH_00212 3.4e-163 IQ KR domain
HAPJLFFH_00214 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
HAPJLFFH_00215 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
HAPJLFFH_00216 1.4e-181 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HAPJLFFH_00217 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HAPJLFFH_00218 3.3e-305 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HAPJLFFH_00219 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HAPJLFFH_00220 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
HAPJLFFH_00221 5.2e-240 hom 1.1.1.3 E Homoserine dehydrogenase
HAPJLFFH_00222 1.6e-188 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HAPJLFFH_00223 8.9e-278 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HAPJLFFH_00224 3.5e-64
HAPJLFFH_00225 6.1e-58
HAPJLFFH_00226 8.5e-140 V ATPases associated with a variety of cellular activities
HAPJLFFH_00227 1.2e-231 V Efflux ABC transporter, permease protein
HAPJLFFH_00228 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
HAPJLFFH_00229 2.4e-239 dapE 3.5.1.18 E Peptidase dimerisation domain
HAPJLFFH_00230 0.0 rne 3.1.26.12 J Ribonuclease E/G family
HAPJLFFH_00231 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HAPJLFFH_00232 3.1e-40 rpmA J Ribosomal L27 protein
HAPJLFFH_00233 2e-213 K Psort location Cytoplasmic, score
HAPJLFFH_00234 4.8e-299 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAPJLFFH_00235 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAPJLFFH_00236 2e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HAPJLFFH_00238 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HAPJLFFH_00239 1.8e-116 nusG K Participates in transcription elongation, termination and antitermination
HAPJLFFH_00240 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
HAPJLFFH_00241 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HAPJLFFH_00242 3.4e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HAPJLFFH_00243 7.5e-202 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HAPJLFFH_00244 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
HAPJLFFH_00245 3.4e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAPJLFFH_00246 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HAPJLFFH_00247 7e-50
HAPJLFFH_00248 3.6e-27
HAPJLFFH_00249 7.9e-169 T Pfam Adenylate and Guanylate cyclase catalytic domain
HAPJLFFH_00250 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HAPJLFFH_00251 1.1e-79 ssb1 L Single-stranded DNA-binding protein
HAPJLFFH_00252 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAPJLFFH_00253 6.6e-70 rplI J Binds to the 23S rRNA
HAPJLFFH_00254 2e-35 S Parallel beta-helix repeats
HAPJLFFH_00255 1.2e-65 E Domain of unknown function (DUF5011)
HAPJLFFH_00257 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HAPJLFFH_00258 3e-129 M Protein of unknown function (DUF3152)
HAPJLFFH_00259 4.1e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAPJLFFH_00260 1.9e-147 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAPJLFFH_00261 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
HAPJLFFH_00262 0.0 inlJ M domain protein
HAPJLFFH_00263 2.6e-286 M LPXTG cell wall anchor motif
HAPJLFFH_00264 4.8e-213 3.4.22.70 M Sortase family
HAPJLFFH_00265 1.8e-62 S Domain of unknown function (DUF4854)
HAPJLFFH_00266 1.9e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HAPJLFFH_00267 9.6e-30 2.1.1.72 S Protein conserved in bacteria
HAPJLFFH_00268 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HAPJLFFH_00269 2.1e-132 M Mechanosensitive ion channel
HAPJLFFH_00270 1.7e-119 K Bacterial regulatory proteins, tetR family
HAPJLFFH_00271 7.7e-241 MA20_36090 S Psort location Cytoplasmic, score 8.87
HAPJLFFH_00272 4.2e-233 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HAPJLFFH_00273 5.6e-79 M Belongs to the glycosyl hydrolase 28 family
HAPJLFFH_00275 4.5e-45 K Transcriptional regulator
HAPJLFFH_00276 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HAPJLFFH_00278 1.6e-32
HAPJLFFH_00283 6.3e-131 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
HAPJLFFH_00284 3e-237 K Helix-turn-helix XRE-family like proteins
HAPJLFFH_00285 8.1e-54 relB L RelB antitoxin
HAPJLFFH_00286 2.6e-17 T Toxic component of a toxin-antitoxin (TA) module
HAPJLFFH_00287 1.7e-131 K helix_turn_helix, mercury resistance
HAPJLFFH_00288 4.3e-242 yxiO S Vacuole effluxer Atg22 like
HAPJLFFH_00290 6.5e-201 yegV G pfkB family carbohydrate kinase
HAPJLFFH_00291 1.4e-29 rpmB J Ribosomal L28 family
HAPJLFFH_00292 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
HAPJLFFH_00293 1.3e-219 steT E amino acid
HAPJLFFH_00296 0.0
HAPJLFFH_00297 1.9e-247 U Sodium:dicarboxylate symporter family
HAPJLFFH_00298 3.1e-122 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HAPJLFFH_00299 1.8e-107 XK27_02070 S Nitroreductase family
HAPJLFFH_00300 8.9e-83 hsp20 O Hsp20/alpha crystallin family
HAPJLFFH_00301 1.4e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HAPJLFFH_00302 2.9e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAPJLFFH_00303 1.8e-34 CP_0960 S Belongs to the UPF0109 family
HAPJLFFH_00304 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HAPJLFFH_00305 4.2e-294 ydfD EK Alanine-glyoxylate amino-transferase
HAPJLFFH_00306 1.3e-93 argO S LysE type translocator
HAPJLFFH_00307 3.4e-219 S Endonuclease/Exonuclease/phosphatase family
HAPJLFFH_00308 8.4e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAPJLFFH_00309 1.4e-164 P Cation efflux family
HAPJLFFH_00310 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAPJLFFH_00311 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
HAPJLFFH_00312 0.0 yjjK S ABC transporter
HAPJLFFH_00313 2e-58 S Protein of unknown function (DUF3039)
HAPJLFFH_00314 2.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAPJLFFH_00315 1.4e-106
HAPJLFFH_00316 1e-113 yceD S Uncharacterized ACR, COG1399
HAPJLFFH_00317 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HAPJLFFH_00318 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HAPJLFFH_00319 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HAPJLFFH_00320 7.6e-92 ilvN 2.2.1.6 E ACT domain
HAPJLFFH_00322 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAPJLFFH_00323 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HAPJLFFH_00324 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HAPJLFFH_00325 2.4e-176 S Auxin Efflux Carrier
HAPJLFFH_00328 0.0 pgi 5.3.1.9 G Belongs to the GPI family
HAPJLFFH_00329 1.5e-190
HAPJLFFH_00331 6.9e-201
HAPJLFFH_00333 5.5e-122 mgtC S MgtC family
HAPJLFFH_00334 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
HAPJLFFH_00335 3.5e-277 abcT3 P ATPases associated with a variety of cellular activities
HAPJLFFH_00336 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
HAPJLFFH_00338 1.4e-173 K Putative sugar-binding domain
HAPJLFFH_00339 7.5e-212 gatC G PTS system sugar-specific permease component
HAPJLFFH_00340 4.7e-293 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
HAPJLFFH_00341 1.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HAPJLFFH_00342 1.1e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HAPJLFFH_00343 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HAPJLFFH_00344 1.3e-156 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HAPJLFFH_00345 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAPJLFFH_00346 8.7e-201 K helix_turn _helix lactose operon repressor
HAPJLFFH_00347 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HAPJLFFH_00348 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HAPJLFFH_00349 4e-110 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HAPJLFFH_00352 1.9e-294 G Glycosyl hydrolases family 43
HAPJLFFH_00353 9.4e-201 K helix_turn _helix lactose operon repressor
HAPJLFFH_00354 9.3e-11 3.2.1.14 GH18 EM Domain of unknown function (DUF5011)
HAPJLFFH_00355 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
HAPJLFFH_00356 1.6e-134 L Protein of unknown function (DUF1524)
HAPJLFFH_00357 7.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
HAPJLFFH_00358 3.4e-305 EGP Major facilitator Superfamily
HAPJLFFH_00359 1e-143 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HAPJLFFH_00360 7.1e-94 lacG G Binding-protein-dependent transport system inner membrane component
HAPJLFFH_00361 4.7e-109 M1-530 S Protein of unknown function (DUF4127)
HAPJLFFH_00362 1.3e-57 2.7.1.2 GK ROK family
HAPJLFFH_00363 4.9e-85 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HAPJLFFH_00366 2.9e-87 topB 5.99.1.2 L DNA topoisomerase
HAPJLFFH_00367 5.7e-88 topB 5.99.1.2 L DNA topoisomerase
HAPJLFFH_00370 3.6e-69
HAPJLFFH_00371 6e-58 S pathogenesis
HAPJLFFH_00372 1.4e-36 L Psort location Cytoplasmic, score 8.87
HAPJLFFH_00373 1.8e-163 tnp7109-2 L PFAM Transposase, Mutator family
HAPJLFFH_00374 9.8e-105 L Integrase core domain
HAPJLFFH_00375 1.4e-12 L Transposase
HAPJLFFH_00376 4.6e-103 K cell envelope-related transcriptional attenuator
HAPJLFFH_00378 2e-217
HAPJLFFH_00379 1.3e-179 S G5
HAPJLFFH_00380 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HAPJLFFH_00381 2.8e-119 F Domain of unknown function (DUF4916)
HAPJLFFH_00382 6.9e-161 mhpC I Alpha/beta hydrolase family
HAPJLFFH_00383 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HAPJLFFH_00384 0.0 enhA_2 S L,D-transpeptidase catalytic domain
HAPJLFFH_00385 4.9e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HAPJLFFH_00386 7.7e-239 S Uncharacterized conserved protein (DUF2183)
HAPJLFFH_00387 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HAPJLFFH_00388 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HAPJLFFH_00389 8.5e-47 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HAPJLFFH_00390 5.8e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HAPJLFFH_00391 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
HAPJLFFH_00392 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HAPJLFFH_00393 3.1e-217 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
HAPJLFFH_00394 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HAPJLFFH_00395 3.1e-139 glpR K DeoR C terminal sensor domain
HAPJLFFH_00396 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HAPJLFFH_00397 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HAPJLFFH_00398 8.6e-243 EGP Sugar (and other) transporter
HAPJLFFH_00399 4.2e-43 gcvR T Belongs to the UPF0237 family
HAPJLFFH_00400 9.4e-253 S UPF0210 protein
HAPJLFFH_00401 9.9e-109
HAPJLFFH_00403 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HAPJLFFH_00404 1.5e-07 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
HAPJLFFH_00405 5.9e-52 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
HAPJLFFH_00406 3.5e-34 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G xyloglucan:xyloglucosyl transferase activity
HAPJLFFH_00407 2.1e-182 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HAPJLFFH_00408 9.6e-102
HAPJLFFH_00409 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPJLFFH_00410 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPJLFFH_00411 1.3e-96 T Forkhead associated domain
HAPJLFFH_00412 1.1e-67 B Belongs to the OprB family
HAPJLFFH_00413 2e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
HAPJLFFH_00414 0.0 E Transglutaminase-like superfamily
HAPJLFFH_00415 1.4e-229 S Protein of unknown function DUF58
HAPJLFFH_00416 1.4e-232 S ATPase family associated with various cellular activities (AAA)
HAPJLFFH_00417 0.0 S Fibronectin type 3 domain
HAPJLFFH_00418 4e-270 KLT Protein tyrosine kinase
HAPJLFFH_00419 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HAPJLFFH_00420 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HAPJLFFH_00421 8.6e-159 K -acetyltransferase
HAPJLFFH_00422 1.7e-257 G Major Facilitator Superfamily
HAPJLFFH_00423 8.4e-66 gsiA P ATPase activity
HAPJLFFH_00424 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HAPJLFFH_00425 2.7e-10 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HAPJLFFH_00426 6.4e-24 relB L RelB antitoxin
HAPJLFFH_00427 5.5e-35 L Transposase
HAPJLFFH_00428 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HAPJLFFH_00429 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAPJLFFH_00430 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAPJLFFH_00431 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
HAPJLFFH_00432 1.7e-286 O Subtilase family
HAPJLFFH_00433 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAPJLFFH_00434 2.6e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAPJLFFH_00435 3.6e-271 S zinc finger
HAPJLFFH_00436 8.2e-114 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HAPJLFFH_00437 2.9e-229 aspB E Aminotransferase class-V
HAPJLFFH_00438 1.8e-157 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HAPJLFFH_00439 4.5e-132 tmp1 S Domain of unknown function (DUF4391)
HAPJLFFH_00440 2.6e-149 moeB 2.7.7.80 H ThiF family
HAPJLFFH_00441 9.1e-256 cdr OP Sulfurtransferase TusA
HAPJLFFH_00442 8.1e-182 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HAPJLFFH_00445 8e-171 S Endonuclease/Exonuclease/phosphatase family
HAPJLFFH_00446 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAPJLFFH_00447 5.2e-270 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAPJLFFH_00448 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HAPJLFFH_00449 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAPJLFFH_00451 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HAPJLFFH_00452 1.2e-166
HAPJLFFH_00453 5.8e-261 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
HAPJLFFH_00454 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
HAPJLFFH_00455 1.7e-88 K MarR family
HAPJLFFH_00456 0.0 V ABC transporter, ATP-binding protein
HAPJLFFH_00457 0.0 V ABC transporter transmembrane region
HAPJLFFH_00458 8.8e-168 S Patatin-like phospholipase
HAPJLFFH_00459 4.6e-154 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HAPJLFFH_00460 2.3e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HAPJLFFH_00461 7.6e-115 S Vitamin K epoxide reductase
HAPJLFFH_00462 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
HAPJLFFH_00463 2.3e-31 S Protein of unknown function (DUF3107)
HAPJLFFH_00464 1e-244 mphA S Aminoglycoside phosphotransferase
HAPJLFFH_00465 2e-280 uvrD2 3.6.4.12 L DNA helicase
HAPJLFFH_00466 1.1e-286 S Zincin-like metallopeptidase
HAPJLFFH_00467 7.6e-152 lon T Belongs to the peptidase S16 family
HAPJLFFH_00468 5.7e-47 S Protein of unknown function (DUF3052)
HAPJLFFH_00469 8.1e-196 K helix_turn _helix lactose operon repressor
HAPJLFFH_00470 1.2e-61 S Thiamine-binding protein
HAPJLFFH_00471 5.9e-163 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HAPJLFFH_00472 6.9e-231 O AAA domain (Cdc48 subfamily)
HAPJLFFH_00473 1.3e-84
HAPJLFFH_00474 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAPJLFFH_00475 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HAPJLFFH_00476 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
HAPJLFFH_00477 2.3e-300 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HAPJLFFH_00478 3.6e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAPJLFFH_00479 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAPJLFFH_00480 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HAPJLFFH_00481 2.1e-42 yggT S YGGT family
HAPJLFFH_00482 9.7e-90 3.1.21.3 V DivIVA protein
HAPJLFFH_00483 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAPJLFFH_00484 2e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HAPJLFFH_00486 6e-63
HAPJLFFH_00487 5.2e-147 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HAPJLFFH_00488 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HAPJLFFH_00489 5.9e-197 ftsE D Cell division ATP-binding protein FtsE
HAPJLFFH_00490 9.2e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HAPJLFFH_00491 2.8e-162 usp 3.5.1.28 CBM50 D CHAP domain protein
HAPJLFFH_00492 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HAPJLFFH_00493 4.9e-150 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HAPJLFFH_00494 5.7e-19
HAPJLFFH_00495 3.3e-23
HAPJLFFH_00497 2.4e-183 2.7.11.1 NU Tfp pilus assembly protein FimV
HAPJLFFH_00498 3.7e-221 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HAPJLFFH_00499 3.9e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HAPJLFFH_00500 1.2e-291 I acetylesterase activity
HAPJLFFH_00501 1.3e-142 recO L Involved in DNA repair and RecF pathway recombination
HAPJLFFH_00502 1.5e-154 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAPJLFFH_00503 5.1e-192 ywqG S Domain of unknown function (DUF1963)
HAPJLFFH_00504 1.7e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HAPJLFFH_00505 8.8e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HAPJLFFH_00506 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HAPJLFFH_00507 3.1e-105 S zinc-ribbon domain
HAPJLFFH_00508 1.6e-46 yhbY J CRS1_YhbY
HAPJLFFH_00509 0.0 4.2.1.53 S MCRA family
HAPJLFFH_00512 1.7e-201 K WYL domain
HAPJLFFH_00513 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
HAPJLFFH_00514 6.4e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
HAPJLFFH_00515 1.2e-76 yneG S Domain of unknown function (DUF4186)
HAPJLFFH_00517 7.8e-08 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HAPJLFFH_00518 2.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAPJLFFH_00519 3.2e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HAPJLFFH_00520 2.1e-224 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HAPJLFFH_00521 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HAPJLFFH_00522 8.5e-112
HAPJLFFH_00523 1.4e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HAPJLFFH_00524 1.7e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HAPJLFFH_00525 1.4e-283 S Uncharacterized protein conserved in bacteria (DUF2252)
HAPJLFFH_00526 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
HAPJLFFH_00527 7.5e-250 S Domain of unknown function (DUF5067)
HAPJLFFH_00528 1.1e-57 EGP Major facilitator Superfamily
HAPJLFFH_00529 1.4e-176 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HAPJLFFH_00530 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HAPJLFFH_00531 2.4e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HAPJLFFH_00532 1.5e-172
HAPJLFFH_00533 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAPJLFFH_00534 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HAPJLFFH_00535 6e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAPJLFFH_00536 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HAPJLFFH_00537 2.1e-48 M Lysin motif
HAPJLFFH_00538 2.3e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HAPJLFFH_00539 1.9e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HAPJLFFH_00540 0.0 L DNA helicase
HAPJLFFH_00541 1.3e-90 mraZ K Belongs to the MraZ family
HAPJLFFH_00542 1.1e-193 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HAPJLFFH_00543 2.5e-59 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HAPJLFFH_00544 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HAPJLFFH_00545 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAPJLFFH_00546 1.5e-283 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HAPJLFFH_00547 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAPJLFFH_00548 6e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HAPJLFFH_00549 4.3e-226 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HAPJLFFH_00550 6.5e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAPJLFFH_00551 3.7e-293 murC 6.3.2.8 M Belongs to the MurCDEF family
HAPJLFFH_00552 1.8e-157 ftsQ 6.3.2.4 D Cell division protein FtsQ
HAPJLFFH_00553 6.2e-122 3.5.1.28 M NLP P60 protein
HAPJLFFH_00554 5.3e-53 S SPP1 phage holin
HAPJLFFH_00556 1e-41
HAPJLFFH_00557 4.4e-86 L DNA integration
HAPJLFFH_00559 2.2e-24
HAPJLFFH_00560 3e-28
HAPJLFFH_00562 3.4e-79 S Psort location Cytoplasmic, score
HAPJLFFH_00563 1.7e-58
HAPJLFFH_00564 1.8e-117 NT phage tail tape measure protein
HAPJLFFH_00566 4.8e-18
HAPJLFFH_00567 3.3e-65 eae N domain, Protein
HAPJLFFH_00568 2.1e-37
HAPJLFFH_00569 2.3e-07
HAPJLFFH_00570 7.8e-31
HAPJLFFH_00571 2.1e-14 S Phage protein Gp19/Gp15/Gp42
HAPJLFFH_00572 2.3e-149 S Phage capsid family
HAPJLFFH_00573 8e-29
HAPJLFFH_00574 5.9e-50
HAPJLFFH_00575 1e-85 S Phage portal protein, SPP1 Gp6-like
HAPJLFFH_00576 4.7e-149 S Terminase
HAPJLFFH_00577 1.2e-13
HAPJLFFH_00580 1.3e-12
HAPJLFFH_00581 1.2e-65 1.8.4.10, 1.8.4.8 EH sulfate reduction
HAPJLFFH_00582 1.2e-32 S Phage plasmid primase, P4 family domain protein
HAPJLFFH_00583 6.3e-17 V HNH nucleases
HAPJLFFH_00585 3.4e-73 S HicB_like antitoxin of bacterial toxin-antitoxin system
HAPJLFFH_00586 1.9e-32 N HicA toxin of bacterial toxin-antitoxin,
HAPJLFFH_00587 3.9e-107
HAPJLFFH_00593 1.3e-25 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HAPJLFFH_00594 2.8e-35 V HNH endonuclease
HAPJLFFH_00597 4.1e-144 L IstB-like ATP binding protein
HAPJLFFH_00598 5.8e-296 L PFAM Integrase catalytic
HAPJLFFH_00599 6.4e-55 K ParB-like nuclease domain
HAPJLFFH_00601 2.2e-11
HAPJLFFH_00602 2.8e-48 ssb1 L Single-stranded DNA-binding protein
HAPJLFFH_00609 5.9e-86 S KilA-N
HAPJLFFH_00610 8e-35
HAPJLFFH_00611 2.9e-68
HAPJLFFH_00613 5.2e-65 gepA S Protein of unknown function (DUF4065)
HAPJLFFH_00614 5.2e-151 int8 L Phage integrase family
HAPJLFFH_00615 1.3e-37
HAPJLFFH_00617 1e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HAPJLFFH_00618 4.4e-236 G Major Facilitator Superfamily
HAPJLFFH_00619 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
HAPJLFFH_00620 1.1e-223 GK ROK family
HAPJLFFH_00621 6.4e-131 cutC P Participates in the control of copper homeostasis
HAPJLFFH_00622 1e-215 GK ROK family
HAPJLFFH_00623 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAPJLFFH_00624 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
HAPJLFFH_00625 2e-305 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
HAPJLFFH_00626 6.7e-185 dppB EP Binding-protein-dependent transport system inner membrane component
HAPJLFFH_00627 8.7e-191 dppC EP Binding-protein-dependent transport system inner membrane component
HAPJLFFH_00628 0.0 P Belongs to the ABC transporter superfamily
HAPJLFFH_00629 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HAPJLFFH_00630 4.3e-97 3.6.1.55 F NUDIX domain
HAPJLFFH_00632 3.1e-287 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
HAPJLFFH_00633 0.0 smc D Required for chromosome condensation and partitioning
HAPJLFFH_00634 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HAPJLFFH_00635 9.5e-244 yxbA 6.3.1.12 S ATP-grasp
HAPJLFFH_00636 5.8e-230 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
HAPJLFFH_00637 1.3e-190 V Acetyltransferase (GNAT) domain
HAPJLFFH_00638 2.2e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAPJLFFH_00639 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HAPJLFFH_00640 2e-64
HAPJLFFH_00641 9.1e-194 galM 5.1.3.3 G Aldose 1-epimerase
HAPJLFFH_00642 2.2e-179 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAPJLFFH_00644 3.2e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAPJLFFH_00645 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAPJLFFH_00646 2.3e-133 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HAPJLFFH_00647 4.1e-07 S Spermine/spermidine synthase domain
HAPJLFFH_00649 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAPJLFFH_00650 2.1e-25 rpmI J Ribosomal protein L35
HAPJLFFH_00651 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HAPJLFFH_00652 2.9e-179 xerD D recombinase XerD
HAPJLFFH_00653 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HAPJLFFH_00654 1.4e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAPJLFFH_00655 2.5e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAPJLFFH_00656 1.1e-149 nrtR 3.6.1.55 F NUDIX hydrolase
HAPJLFFH_00657 7.5e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HAPJLFFH_00658 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HAPJLFFH_00659 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
HAPJLFFH_00660 5.7e-236 iscS1 2.8.1.7 E Aminotransferase class-V
HAPJLFFH_00661 0.0 typA T Elongation factor G C-terminus
HAPJLFFH_00662 1.7e-80
HAPJLFFH_00663 1.8e-195 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HAPJLFFH_00664 7.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HAPJLFFH_00665 7.3e-42
HAPJLFFH_00666 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HAPJLFFH_00667 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
HAPJLFFH_00668 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
HAPJLFFH_00669 0.0 oppD P Belongs to the ABC transporter superfamily
HAPJLFFH_00670 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HAPJLFFH_00671 3.1e-275 pepC 3.4.22.40 E Peptidase C1-like family
HAPJLFFH_00672 1.1e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HAPJLFFH_00673 3.2e-139 S Protein of unknown function (DUF3710)
HAPJLFFH_00674 1.7e-129 S Protein of unknown function (DUF3159)
HAPJLFFH_00675 3.8e-248 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAPJLFFH_00676 8.3e-108
HAPJLFFH_00677 0.0 ctpE P E1-E2 ATPase
HAPJLFFH_00678 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HAPJLFFH_00680 1.8e-175 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAPJLFFH_00681 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HAPJLFFH_00682 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HAPJLFFH_00683 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAPJLFFH_00684 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAPJLFFH_00685 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HAPJLFFH_00686 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAPJLFFH_00687 4.3e-138 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HAPJLFFH_00689 0.0 arc O AAA ATPase forming ring-shaped complexes
HAPJLFFH_00690 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HAPJLFFH_00691 3e-161 hisN 3.1.3.25 G Inositol monophosphatase family
HAPJLFFH_00692 9.2e-11 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HAPJLFFH_00693 1e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HAPJLFFH_00694 8.1e-42 hup L Belongs to the bacterial histone-like protein family
HAPJLFFH_00695 0.0 S Lysylphosphatidylglycerol synthase TM region
HAPJLFFH_00696 3.3e-280 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HAPJLFFH_00697 7.5e-291 S PGAP1-like protein
HAPJLFFH_00699 2.5e-75
HAPJLFFH_00700 2e-146 S von Willebrand factor (vWF) type A domain
HAPJLFFH_00701 1.8e-190 S von Willebrand factor (vWF) type A domain
HAPJLFFH_00702 6.4e-94
HAPJLFFH_00703 7.2e-178 S Protein of unknown function DUF58
HAPJLFFH_00704 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
HAPJLFFH_00705 1.6e-143 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAPJLFFH_00706 4.9e-70 S LytR cell envelope-related transcriptional attenuator
HAPJLFFH_00707 8.3e-44 cspA K 'Cold-shock' DNA-binding domain
HAPJLFFH_00708 6.1e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HAPJLFFH_00709 1.7e-10 S Proteins of 100 residues with WXG
HAPJLFFH_00710 4.9e-162
HAPJLFFH_00711 1.6e-134 KT Response regulator receiver domain protein
HAPJLFFH_00712 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPJLFFH_00713 1e-66 cspB K 'Cold-shock' DNA-binding domain
HAPJLFFH_00714 2.8e-191 S Protein of unknown function (DUF3027)
HAPJLFFH_00715 3e-184 uspA T Belongs to the universal stress protein A family
HAPJLFFH_00716 0.0 clpC O ATPase family associated with various cellular activities (AAA)
HAPJLFFH_00720 5.1e-217 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HAPJLFFH_00721 7.1e-264 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HAPJLFFH_00722 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HAPJLFFH_00723 9.3e-56 K helix_turn_helix, Lux Regulon
HAPJLFFH_00724 6.9e-86 S Aminoacyl-tRNA editing domain
HAPJLFFH_00725 2e-138 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
HAPJLFFH_00726 2.8e-146 gluB ET Belongs to the bacterial solute-binding protein 3 family
HAPJLFFH_00727 5.2e-111 gluC E Binding-protein-dependent transport system inner membrane component
HAPJLFFH_00728 3.7e-199 gluD E Binding-protein-dependent transport system inner membrane component
HAPJLFFH_00729 1.9e-192 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
HAPJLFFH_00730 0.0 L DEAD DEAH box helicase
HAPJLFFH_00731 7.7e-258 rarA L Recombination factor protein RarA
HAPJLFFH_00733 5.2e-257 EGP Major facilitator Superfamily
HAPJLFFH_00734 0.0 ecfA GP ABC transporter, ATP-binding protein
HAPJLFFH_00735 1.5e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HAPJLFFH_00736 1.7e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
HAPJLFFH_00737 2e-213 E Aminotransferase class I and II
HAPJLFFH_00738 2.2e-137 bioM P ATPases associated with a variety of cellular activities
HAPJLFFH_00739 1.3e-69 2.8.2.22 S Arylsulfotransferase Ig-like domain
HAPJLFFH_00740 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAPJLFFH_00741 0.0 S Tetratricopeptide repeat
HAPJLFFH_00742 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HAPJLFFH_00743 6.3e-210 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HAPJLFFH_00744 3.7e-159 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAPJLFFH_00747 4.2e-19
HAPJLFFH_00748 3.7e-25
HAPJLFFH_00749 3.1e-286 glnA 6.3.1.2 E glutamine synthetase
HAPJLFFH_00750 1e-142 S Domain of unknown function (DUF4191)
HAPJLFFH_00751 1.4e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAPJLFFH_00752 4.6e-103 S Protein of unknown function (DUF3043)
HAPJLFFH_00753 4e-259 argE E Peptidase dimerisation domain
HAPJLFFH_00754 2.4e-190 V N-Acetylmuramoyl-L-alanine amidase
HAPJLFFH_00755 8.7e-153 ytrE V ATPases associated with a variety of cellular activities
HAPJLFFH_00756 1.3e-196
HAPJLFFH_00757 2.4e-229 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
HAPJLFFH_00758 0.0 S Uncharacterised protein family (UPF0182)
HAPJLFFH_00759 4.3e-208 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAPJLFFH_00760 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAPJLFFH_00761 1e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
HAPJLFFH_00763 1e-128 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HAPJLFFH_00764 1.9e-197 GM GDP-mannose 4,6 dehydratase
HAPJLFFH_00765 2.1e-151 GM ABC-2 type transporter
HAPJLFFH_00766 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
HAPJLFFH_00767 1.1e-95 2.3.1.183 M Acetyltransferase (GNAT) domain
HAPJLFFH_00768 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HAPJLFFH_00769 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAPJLFFH_00770 6.9e-297 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
HAPJLFFH_00771 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
HAPJLFFH_00772 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HAPJLFFH_00773 2.5e-101 divIC D Septum formation initiator
HAPJLFFH_00774 5.7e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HAPJLFFH_00775 1.2e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HAPJLFFH_00777 6.1e-97
HAPJLFFH_00778 8.8e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HAPJLFFH_00779 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HAPJLFFH_00780 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAPJLFFH_00782 1e-107
HAPJLFFH_00783 2e-142 yplQ S Haemolysin-III related
HAPJLFFH_00784 6.2e-285 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPJLFFH_00785 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HAPJLFFH_00786 0.0 D FtsK/SpoIIIE family
HAPJLFFH_00787 2.7e-269 K Cell envelope-related transcriptional attenuator domain
HAPJLFFH_00788 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HAPJLFFH_00789 0.0 S Glycosyl transferase, family 2
HAPJLFFH_00790 3.6e-261
HAPJLFFH_00791 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HAPJLFFH_00792 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
HAPJLFFH_00793 1.2e-129 ctsW S Phosphoribosyl transferase domain
HAPJLFFH_00794 2.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
HAPJLFFH_00795 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPJLFFH_00796 1.9e-127 T Response regulator receiver domain protein
HAPJLFFH_00797 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAPJLFFH_00798 5.1e-102 carD K CarD-like/TRCF domain
HAPJLFFH_00799 8.5e-84 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HAPJLFFH_00800 2.1e-138 znuB U ABC 3 transport family
HAPJLFFH_00801 8.2e-165 znuC P ATPases associated with a variety of cellular activities
HAPJLFFH_00802 2.5e-173 P Zinc-uptake complex component A periplasmic
HAPJLFFH_00803 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAPJLFFH_00804 3.6e-242 rpsA J Ribosomal protein S1
HAPJLFFH_00805 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HAPJLFFH_00806 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HAPJLFFH_00807 1.7e-179 terC P Integral membrane protein, TerC family
HAPJLFFH_00808 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
HAPJLFFH_00809 1.8e-110 aspA 3.6.1.13 L NUDIX domain
HAPJLFFH_00811 9.2e-120 pdtaR T Response regulator receiver domain protein
HAPJLFFH_00812 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAPJLFFH_00813 1.9e-172 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HAPJLFFH_00814 1.9e-127 3.6.1.13 L NUDIX domain
HAPJLFFH_00815 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HAPJLFFH_00816 1.4e-218 ykiI
HAPJLFFH_00818 4.2e-135 L Phage integrase family
HAPJLFFH_00819 2.9e-108 3.4.13.21 E Peptidase family S51
HAPJLFFH_00820 1.7e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HAPJLFFH_00821 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAPJLFFH_00822 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HAPJLFFH_00823 1e-281 XK27_07020 S Domain of unknown function (DUF1846)
HAPJLFFH_00824 1.7e-122
HAPJLFFH_00826 9.9e-112 ysdA S Protein of unknown function (DUF1294)
HAPJLFFH_00827 1.2e-27
HAPJLFFH_00828 4.4e-51
HAPJLFFH_00830 1.1e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HAPJLFFH_00831 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HAPJLFFH_00832 3.4e-189 pit P Phosphate transporter family
HAPJLFFH_00833 1.1e-115 MA20_27875 P Protein of unknown function DUF47
HAPJLFFH_00834 3.1e-119 K helix_turn_helix, Lux Regulon
HAPJLFFH_00835 9.2e-234 T Histidine kinase
HAPJLFFH_00836 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HAPJLFFH_00837 6.9e-181 V ATPases associated with a variety of cellular activities
HAPJLFFH_00838 8.1e-227 V ABC-2 family transporter protein
HAPJLFFH_00839 6e-250 V ABC-2 family transporter protein
HAPJLFFH_00840 1.3e-284 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HAPJLFFH_00841 1.9e-65 L Transposase and inactivated derivatives IS30 family
HAPJLFFH_00842 4.1e-144 L IstB-like ATP binding protein
HAPJLFFH_00843 5.8e-296 L PFAM Integrase catalytic
HAPJLFFH_00844 1.3e-102 L Transposase and inactivated derivatives IS30 family
HAPJLFFH_00846 1.4e-96
HAPJLFFH_00847 1.2e-64 D MobA/MobL family
HAPJLFFH_00848 9.5e-175 tnp7109-21 L Integrase core domain
HAPJLFFH_00849 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
HAPJLFFH_00850 6.9e-40
HAPJLFFH_00851 1.1e-110 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
HAPJLFFH_00853 4e-46 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HAPJLFFH_00855 2.4e-240 pbuX F Permease family
HAPJLFFH_00856 4.3e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HAPJLFFH_00857 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
HAPJLFFH_00858 0.0 pcrA 3.6.4.12 L DNA helicase
HAPJLFFH_00859 8.2e-64 S Domain of unknown function (DUF4418)
HAPJLFFH_00860 1.9e-212 V FtsX-like permease family
HAPJLFFH_00861 1.3e-127 lolD V ABC transporter
HAPJLFFH_00862 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAPJLFFH_00863 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
HAPJLFFH_00864 1.9e-135 pgm3 G Phosphoglycerate mutase family
HAPJLFFH_00865 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HAPJLFFH_00866 1.1e-36
HAPJLFFH_00867 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAPJLFFH_00868 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAPJLFFH_00869 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAPJLFFH_00870 1.3e-47 3.4.23.43 S Type IV leader peptidase family
HAPJLFFH_00871 6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAPJLFFH_00872 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAPJLFFH_00873 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HAPJLFFH_00874 5.3e-16
HAPJLFFH_00875 1.7e-120 K helix_turn_helix, Lux Regulon
HAPJLFFH_00876 5.2e-08 3.4.22.70 M Sortase family
HAPJLFFH_00877 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HAPJLFFH_00878 3.6e-290 sufB O FeS assembly protein SufB
HAPJLFFH_00879 2.6e-233 sufD O FeS assembly protein SufD
HAPJLFFH_00880 1.4e-144 sufC O FeS assembly ATPase SufC
HAPJLFFH_00881 3.5e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAPJLFFH_00882 8.8e-101 iscU C SUF system FeS assembly protein, NifU family
HAPJLFFH_00883 1.1e-106 yitW S Iron-sulfur cluster assembly protein
HAPJLFFH_00884 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HAPJLFFH_00885 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
HAPJLFFH_00887 6.7e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HAPJLFFH_00888 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HAPJLFFH_00889 2e-197 phoH T PhoH-like protein
HAPJLFFH_00890 2.2e-99 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HAPJLFFH_00891 2.4e-251 corC S CBS domain
HAPJLFFH_00892 5.1e-187 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAPJLFFH_00893 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HAPJLFFH_00894 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HAPJLFFH_00895 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HAPJLFFH_00896 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HAPJLFFH_00897 4.8e-190 S alpha beta
HAPJLFFH_00898 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HAPJLFFH_00899 2.4e-225 ilvE 2.6.1.42 E Amino-transferase class IV
HAPJLFFH_00900 4e-46 S phosphoesterase or phosphohydrolase
HAPJLFFH_00901 1.5e-143 3.1.4.37 T RNA ligase
HAPJLFFH_00902 4.4e-135 S UPF0126 domain
HAPJLFFH_00903 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
HAPJLFFH_00904 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HAPJLFFH_00905 1.3e-244 hemN H Involved in the biosynthesis of porphyrin-containing compound
HAPJLFFH_00906 8.2e-293 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HAPJLFFH_00907 0.0 tetP J Elongation factor G, domain IV
HAPJLFFH_00908 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HAPJLFFH_00909 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HAPJLFFH_00910 3.6e-82
HAPJLFFH_00911 5.1e-245 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
HAPJLFFH_00912 5.7e-163 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
HAPJLFFH_00913 1.7e-151 ybeM S Carbon-nitrogen hydrolase
HAPJLFFH_00914 3e-50 S Sel1-like repeats.
HAPJLFFH_00915 1.2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HAPJLFFH_00916 1.7e-61 S Short C-terminal domain
HAPJLFFH_00917 1.7e-184 L Transposase
HAPJLFFH_00918 3e-127 XK26_04895
HAPJLFFH_00920 4e-223 K Helix-turn-helix domain protein
HAPJLFFH_00922 6.6e-146 F nucleoside 2-deoxyribosyltransferase
HAPJLFFH_00923 0.0 2.1.1.72, 3.1.21.3, 3.1.21.4 L T5orf172
HAPJLFFH_00924 7.9e-193 2.1.1.72, 3.1.21.4 V Eco57I restriction-modification methylase
HAPJLFFH_00925 8.8e-89 2.1.1.72, 3.1.21.4 V Eco57I restriction-modification methylase
HAPJLFFH_00926 4.3e-106 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HAPJLFFH_00927 0.0 S Protein of unknown function DUF262
HAPJLFFH_00928 2.8e-28
HAPJLFFH_00929 1.4e-92 rarD 3.4.17.13 E Rard protein
HAPJLFFH_00930 1.4e-23 rarD S EamA-like transporter family
HAPJLFFH_00931 1e-178 I alpha/beta hydrolase fold
HAPJLFFH_00932 1.1e-206 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HAPJLFFH_00933 9.9e-100 sixA T Phosphoglycerate mutase family
HAPJLFFH_00934 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HAPJLFFH_00935 6.9e-161 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
HAPJLFFH_00937 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HAPJLFFH_00938 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HAPJLFFH_00939 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HAPJLFFH_00940 1.2e-279 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HAPJLFFH_00941 8.9e-181 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
HAPJLFFH_00942 1.7e-156 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HAPJLFFH_00943 9.6e-180 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HAPJLFFH_00944 1.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAPJLFFH_00945 1e-16 K MerR family regulatory protein
HAPJLFFH_00946 4.7e-196 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HAPJLFFH_00947 2.8e-141
HAPJLFFH_00948 1.3e-16 K Psort location Cytoplasmic, score
HAPJLFFH_00950 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HAPJLFFH_00951 2.9e-238 vbsD V MatE
HAPJLFFH_00952 1.6e-131 S Enoyl-(Acyl carrier protein) reductase
HAPJLFFH_00953 5.1e-133 magIII L endonuclease III
HAPJLFFH_00954 1.1e-92 laaE K Transcriptional regulator PadR-like family
HAPJLFFH_00955 1.8e-176 S Membrane transport protein
HAPJLFFH_00956 3.6e-66 4.1.1.44 S Cupin domain
HAPJLFFH_00957 7.7e-224 hipA 2.7.11.1 S HipA N-terminal domain
HAPJLFFH_00958 3.7e-41 K Helix-turn-helix
HAPJLFFH_00959 3.4e-48 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
HAPJLFFH_00960 4.2e-19
HAPJLFFH_00961 1.9e-101 K Bacterial regulatory proteins, tetR family
HAPJLFFH_00962 5.2e-84 T Domain of unknown function (DUF4234)
HAPJLFFH_00963 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
HAPJLFFH_00964 8.1e-122 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HAPJLFFH_00965 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAPJLFFH_00966 4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
HAPJLFFH_00967 5.7e-61 dkgB S Oxidoreductase, aldo keto reductase family protein
HAPJLFFH_00969 8.2e-287 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HAPJLFFH_00970 0.0 pafB K WYL domain
HAPJLFFH_00971 1.6e-52
HAPJLFFH_00972 0.0 helY L DEAD DEAH box helicase
HAPJLFFH_00973 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HAPJLFFH_00974 7.3e-143 pgp 3.1.3.18 S HAD-hyrolase-like
HAPJLFFH_00977 3.6e-90 K Putative zinc ribbon domain
HAPJLFFH_00978 7.2e-126 S GyrI-like small molecule binding domain
HAPJLFFH_00979 2.6e-24 L DNA integration
HAPJLFFH_00981 5e-63
HAPJLFFH_00982 5.2e-119 K helix_turn_helix, mercury resistance
HAPJLFFH_00983 9.6e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
HAPJLFFH_00984 1.2e-141 S Bacterial protein of unknown function (DUF881)
HAPJLFFH_00985 2.6e-31 sbp S Protein of unknown function (DUF1290)
HAPJLFFH_00986 4e-173 S Bacterial protein of unknown function (DUF881)
HAPJLFFH_00987 6.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAPJLFFH_00988 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
HAPJLFFH_00989 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HAPJLFFH_00990 2.4e-100 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
HAPJLFFH_00991 4.4e-183 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAPJLFFH_00992 4.9e-162 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HAPJLFFH_00993 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HAPJLFFH_00994 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
HAPJLFFH_00995 1.7e-145 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HAPJLFFH_00996 5.3e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HAPJLFFH_00997 5.7e-30
HAPJLFFH_00998 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HAPJLFFH_00999 2.7e-244
HAPJLFFH_01000 1.6e-166 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HAPJLFFH_01001 3.3e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HAPJLFFH_01002 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HAPJLFFH_01003 2.6e-44 yajC U Preprotein translocase subunit
HAPJLFFH_01004 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HAPJLFFH_01005 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HAPJLFFH_01006 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HAPJLFFH_01007 1e-131 yebC K transcriptional regulatory protein
HAPJLFFH_01008 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
HAPJLFFH_01009 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAPJLFFH_01010 1.7e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAPJLFFH_01014 1.5e-214
HAPJLFFH_01018 2.8e-156 S PAC2 family
HAPJLFFH_01019 3.2e-167 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HAPJLFFH_01020 2.1e-159 G Fructosamine kinase
HAPJLFFH_01021 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HAPJLFFH_01022 1.2e-206 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HAPJLFFH_01023 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
HAPJLFFH_01024 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HAPJLFFH_01025 1.2e-143 yoaK S Protein of unknown function (DUF1275)
HAPJLFFH_01026 3.7e-252 brnQ U Component of the transport system for branched-chain amino acids
HAPJLFFH_01028 1.2e-239 mepA_6 V MatE
HAPJLFFH_01029 8e-162 S Sucrose-6F-phosphate phosphohydrolase
HAPJLFFH_01030 9.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HAPJLFFH_01031 8e-33 secG U Preprotein translocase SecG subunit
HAPJLFFH_01032 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HAPJLFFH_01033 2.6e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
HAPJLFFH_01034 3.1e-173 whiA K May be required for sporulation
HAPJLFFH_01035 6.9e-178 rapZ S Displays ATPase and GTPase activities
HAPJLFFH_01036 3e-181 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
HAPJLFFH_01037 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HAPJLFFH_01038 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAPJLFFH_01039 4.7e-77
HAPJLFFH_01040 1.1e-58 V MacB-like periplasmic core domain
HAPJLFFH_01041 3.3e-118 K Transcriptional regulatory protein, C terminal
HAPJLFFH_01042 5e-236 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HAPJLFFH_01043 2.2e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HAPJLFFH_01044 8.9e-303 ybiT S ABC transporter
HAPJLFFH_01045 8.5e-198 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HAPJLFFH_01046 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HAPJLFFH_01047 2.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
HAPJLFFH_01048 7.1e-217 GK ROK family
HAPJLFFH_01049 1.5e-177 2.7.1.2 GK ROK family
HAPJLFFH_01050 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
HAPJLFFH_01051 1.7e-168 G ABC transporter permease
HAPJLFFH_01052 1.1e-173 G Binding-protein-dependent transport system inner membrane component
HAPJLFFH_01053 8.2e-246 G Bacterial extracellular solute-binding protein
HAPJLFFH_01054 8.4e-309 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HAPJLFFH_01055 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HAPJLFFH_01056 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HAPJLFFH_01057 9.8e-230 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HAPJLFFH_01058 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
HAPJLFFH_01059 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HAPJLFFH_01060 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HAPJLFFH_01061 1.8e-127 3.2.1.8 S alpha beta
HAPJLFFH_01062 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAPJLFFH_01063 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HAPJLFFH_01064 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAPJLFFH_01065 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
HAPJLFFH_01066 5.7e-91
HAPJLFFH_01067 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
HAPJLFFH_01068 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HAPJLFFH_01069 3.9e-274 G ABC transporter substrate-binding protein
HAPJLFFH_01070 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
HAPJLFFH_01071 1.8e-130 M Peptidase family M23
HAPJLFFH_01073 6.9e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAPJLFFH_01074 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
HAPJLFFH_01075 3.3e-158 yeaZ 2.3.1.234 O Glycoprotease family
HAPJLFFH_01076 5e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
HAPJLFFH_01077 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
HAPJLFFH_01078 0.0 comE S Competence protein
HAPJLFFH_01079 3.1e-84 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
HAPJLFFH_01080 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAPJLFFH_01081 6.8e-170 ET Bacterial periplasmic substrate-binding proteins
HAPJLFFH_01082 4.8e-171 corA P CorA-like Mg2+ transporter protein
HAPJLFFH_01083 4e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HAPJLFFH_01084 2.2e-298 E Serine carboxypeptidase
HAPJLFFH_01085 0.0 S Psort location Cytoplasmic, score 8.87
HAPJLFFH_01086 2.8e-116 S Domain of unknown function (DUF4194)
HAPJLFFH_01087 8.8e-284 S Psort location Cytoplasmic, score 8.87
HAPJLFFH_01088 2.5e-163 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HAPJLFFH_01089 1.5e-64 yeaO K Protein of unknown function, DUF488
HAPJLFFH_01090 4.4e-120 ydaF_1 J Acetyltransferase (GNAT) domain
HAPJLFFH_01091 1.4e-89 MA20_25245 K FR47-like protein
HAPJLFFH_01092 2.5e-56 K Transcriptional regulator
HAPJLFFH_01093 3.5e-33 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
HAPJLFFH_01095 1.4e-33 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HAPJLFFH_01097 1.2e-185 S Acetyltransferase (GNAT) domain
HAPJLFFH_01098 2.4e-75 qseC 2.7.13.3 T Histidine kinase
HAPJLFFH_01099 1.4e-132 S SOS response associated peptidase (SRAP)
HAPJLFFH_01100 2.1e-123
HAPJLFFH_01101 4.7e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAPJLFFH_01102 1.4e-162 rpoC M heme binding
HAPJLFFH_01103 3.4e-118 EGP Major facilitator Superfamily
HAPJLFFH_01105 1.2e-150 3.6.4.12
HAPJLFFH_01106 1.2e-10 CE Amino acid permease
HAPJLFFH_01107 8.1e-111 ypjC S Putative ABC-transporter type IV
HAPJLFFH_01108 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
HAPJLFFH_01109 3.7e-193 V VanZ like family
HAPJLFFH_01110 1.4e-43 KT RESPONSE REGULATOR receiver
HAPJLFFH_01111 1.1e-53 KT RESPONSE REGULATOR receiver
HAPJLFFH_01112 2.7e-70 pdxH S Pfam:Pyridox_oxidase
HAPJLFFH_01113 1.3e-141 yijF S Domain of unknown function (DUF1287)
HAPJLFFH_01114 1.6e-131 C Putative TM nitroreductase
HAPJLFFH_01115 5.2e-101
HAPJLFFH_01117 7.9e-254 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
HAPJLFFH_01118 7.2e-77 S Bacterial PH domain
HAPJLFFH_01119 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HAPJLFFH_01120 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HAPJLFFH_01121 1.7e-262 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAPJLFFH_01123 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAPJLFFH_01124 1.2e-143 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAPJLFFH_01125 1.4e-93
HAPJLFFH_01126 3.1e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAPJLFFH_01127 6.6e-284 thrC 4.2.3.1 E Threonine synthase N terminus
HAPJLFFH_01128 4e-122 S ABC-2 family transporter protein
HAPJLFFH_01129 3.7e-126 S ABC-2 family transporter protein
HAPJLFFH_01130 7e-178 V ATPases associated with a variety of cellular activities
HAPJLFFH_01131 4.8e-58 K helix_turn_helix gluconate operon transcriptional repressor
HAPJLFFH_01132 8.9e-124 S Haloacid dehalogenase-like hydrolase
HAPJLFFH_01133 3.5e-292 recN L May be involved in recombinational repair of damaged DNA
HAPJLFFH_01134 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAPJLFFH_01135 3.3e-235 trkB P Cation transport protein
HAPJLFFH_01136 6.8e-116 trkA P TrkA-N domain
HAPJLFFH_01137 9.8e-102
HAPJLFFH_01138 2e-135 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HAPJLFFH_01140 1.1e-189 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HAPJLFFH_01141 7.7e-158 L Tetratricopeptide repeat
HAPJLFFH_01142 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAPJLFFH_01143 1.6e-143 S Putative ABC-transporter type IV
HAPJLFFH_01144 8e-108 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HAPJLFFH_01145 3.1e-281 argH 4.3.2.1 E argininosuccinate lyase
HAPJLFFH_01146 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HAPJLFFH_01147 7.9e-280 3.6.4.12 K Putative DNA-binding domain
HAPJLFFH_01148 1.9e-129 3.1.21.3 V type I restriction modification DNA specificity domain
HAPJLFFH_01149 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
HAPJLFFH_01150 2.4e-158 S Domain of unknown function (DUF4357)
HAPJLFFH_01151 2.4e-30
HAPJLFFH_01152 8e-179 L Phage integrase family
HAPJLFFH_01153 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HAPJLFFH_01154 1.1e-84 argR K Regulates arginine biosynthesis genes
HAPJLFFH_01155 3.3e-183 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAPJLFFH_01156 1.9e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HAPJLFFH_01157 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HAPJLFFH_01158 7.9e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HAPJLFFH_01159 5.9e-205 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HAPJLFFH_01160 8.6e-87
HAPJLFFH_01161 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HAPJLFFH_01162 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HAPJLFFH_01163 5.4e-161 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAPJLFFH_01164 5.8e-135 ybbL V ATPases associated with a variety of cellular activities
HAPJLFFH_01165 2.5e-136 ybbM V Uncharacterised protein family (UPF0014)
HAPJLFFH_01166 3e-53 IQ oxidoreductase activity
HAPJLFFH_01168 8.2e-84 K AraC-like ligand binding domain
HAPJLFFH_01169 6.9e-237 rutG F Permease family
HAPJLFFH_01170 3.1e-158 3.1.3.73 G Phosphoglycerate mutase family
HAPJLFFH_01171 5.1e-63 S Phospholipase/Carboxylesterase
HAPJLFFH_01172 3.2e-187 MA20_14895 S Conserved hypothetical protein 698
HAPJLFFH_01173 6.6e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
HAPJLFFH_01174 2.9e-119 3.1.3.27 E haloacid dehalogenase-like hydrolase
HAPJLFFH_01175 1.3e-290 2.4.1.166 GT2 M Glycosyltransferase like family 2
HAPJLFFH_01176 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HAPJLFFH_01177 2.1e-125 ypfH S Phospholipase/Carboxylesterase
HAPJLFFH_01178 3.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HAPJLFFH_01179 7.5e-39
HAPJLFFH_01180 3.9e-33 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HAPJLFFH_01181 5.2e-65 S Zincin-like metallopeptidase
HAPJLFFH_01182 2.7e-87 S Helix-turn-helix
HAPJLFFH_01183 7.1e-199 S Short C-terminal domain
HAPJLFFH_01184 2.7e-22
HAPJLFFH_01185 3.4e-148
HAPJLFFH_01186 4.5e-79 K Psort location Cytoplasmic, score
HAPJLFFH_01187 5e-256 KLT Protein tyrosine kinase
HAPJLFFH_01188 9.7e-63 S Cupin 2, conserved barrel domain protein
HAPJLFFH_01189 2.8e-157 ksgA 2.1.1.182 J Methyltransferase domain
HAPJLFFH_01190 5.6e-59 yccF S Inner membrane component domain
HAPJLFFH_01191 1.2e-118 E Psort location Cytoplasmic, score 8.87
HAPJLFFH_01192 1.1e-245 XK27_00240 K Fic/DOC family
HAPJLFFH_01193 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HAPJLFFH_01194 4.4e-230 mtnE 2.6.1.83 E Aminotransferase class I and II
HAPJLFFH_01195 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
HAPJLFFH_01196 1.5e-203 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAPJLFFH_01197 1.7e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
HAPJLFFH_01198 2.2e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
HAPJLFFH_01199 1.4e-147 P NLPA lipoprotein
HAPJLFFH_01200 1.3e-168 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
HAPJLFFH_01201 3.2e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAPJLFFH_01202 5e-265 pip 3.4.11.5 S alpha/beta hydrolase fold
HAPJLFFH_01203 0.0 tcsS2 T Histidine kinase
HAPJLFFH_01204 2.6e-130 K helix_turn_helix, Lux Regulon
HAPJLFFH_01205 0.0 phoN I PAP2 superfamily
HAPJLFFH_01206 0.0 MV MacB-like periplasmic core domain
HAPJLFFH_01207 1.3e-161 V ABC transporter, ATP-binding protein
HAPJLFFH_01208 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
HAPJLFFH_01209 1.6e-157 S Putative ABC-transporter type IV
HAPJLFFH_01210 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HAPJLFFH_01211 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HAPJLFFH_01212 1.9e-56 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HAPJLFFH_01213 5.7e-283 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HAPJLFFH_01214 7.2e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
HAPJLFFH_01215 1.1e-70 yraN L Belongs to the UPF0102 family
HAPJLFFH_01216 4.6e-185 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
HAPJLFFH_01217 1.3e-117 safC S O-methyltransferase
HAPJLFFH_01218 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
HAPJLFFH_01219 1.2e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HAPJLFFH_01220 1e-234 patB 4.4.1.8 E Aminotransferase, class I II
HAPJLFFH_01223 8.5e-243 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAPJLFFH_01224 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAPJLFFH_01225 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAPJLFFH_01226 6.7e-254 clcA_2 P Voltage gated chloride channel
HAPJLFFH_01227 8.1e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HAPJLFFH_01228 1.2e-249 rnd 3.1.13.5 J 3'-5' exonuclease
HAPJLFFH_01229 6.3e-113 S Protein of unknown function (DUF3000)
HAPJLFFH_01230 3.3e-174 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAPJLFFH_01231 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HAPJLFFH_01232 4.9e-40
HAPJLFFH_01233 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAPJLFFH_01234 3.8e-223 S Peptidase dimerisation domain
HAPJLFFH_01235 5.2e-93 P ABC-type metal ion transport system permease component
HAPJLFFH_01236 4.6e-165 S Sucrose-6F-phosphate phosphohydrolase
HAPJLFFH_01237 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAPJLFFH_01238 1.1e-49 relB L RelB antitoxin
HAPJLFFH_01239 1.1e-67 T Toxic component of a toxin-antitoxin (TA) module
HAPJLFFH_01240 1.3e-207 E Belongs to the peptidase S1B family
HAPJLFFH_01241 1.4e-12
HAPJLFFH_01242 2.7e-28
HAPJLFFH_01243 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAPJLFFH_01244 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HAPJLFFH_01245 1.4e-47 S Domain of unknown function (DUF4193)
HAPJLFFH_01246 1.7e-172 S Protein of unknown function (DUF3071)
HAPJLFFH_01247 8.6e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
HAPJLFFH_01248 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HAPJLFFH_01249 0.0 lhr L DEAD DEAH box helicase
HAPJLFFH_01250 1.9e-24 yozG K Cro/C1-type HTH DNA-binding domain
HAPJLFFH_01251 2e-49 S Protein of unknown function (DUF2975)
HAPJLFFH_01252 4.4e-277 aspA 4.3.1.1 E Fumarase C C-terminus
HAPJLFFH_01253 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HAPJLFFH_01254 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HAPJLFFH_01255 3.5e-123
HAPJLFFH_01256 7.4e-200 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
HAPJLFFH_01257 0.0 pknL 2.7.11.1 KLT PASTA
HAPJLFFH_01258 1.8e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
HAPJLFFH_01259 6.2e-108
HAPJLFFH_01260 1.8e-190 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAPJLFFH_01261 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HAPJLFFH_01262 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HAPJLFFH_01264 3.6e-27 marR5 K Winged helix DNA-binding domain
HAPJLFFH_01265 7.1e-74 recX S Modulates RecA activity
HAPJLFFH_01266 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAPJLFFH_01267 3.7e-40 S Protein of unknown function (DUF3046)
HAPJLFFH_01268 1.4e-79 K Helix-turn-helix XRE-family like proteins
HAPJLFFH_01269 3.8e-96 cinA 3.5.1.42 S Belongs to the CinA family
HAPJLFFH_01270 9.2e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAPJLFFH_01271 0.0 ftsK D FtsK SpoIIIE family protein
HAPJLFFH_01272 2e-137 fic D Fic/DOC family
HAPJLFFH_01273 4.1e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAPJLFFH_01274 1.3e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HAPJLFFH_01275 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HAPJLFFH_01276 3e-168 ydeD EG EamA-like transporter family
HAPJLFFH_01277 6.6e-132 ybhL S Belongs to the BI1 family
HAPJLFFH_01278 2e-96 S Domain of unknown function (DUF5067)
HAPJLFFH_01279 5.2e-243 T Histidine kinase
HAPJLFFH_01280 5.8e-296 L PFAM Integrase catalytic
HAPJLFFH_01281 4.1e-144 L IstB-like ATP binding protein
HAPJLFFH_01282 1.1e-116 K helix_turn_helix, Lux Regulon
HAPJLFFH_01283 0.0 S Protein of unknown function DUF262
HAPJLFFH_01284 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HAPJLFFH_01285 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HAPJLFFH_01286 1e-237 carA 6.3.5.5 F Belongs to the CarA family
HAPJLFFH_01287 1.3e-93 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAPJLFFH_01288 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAPJLFFH_01290 1.1e-190 EGP Transmembrane secretion effector
HAPJLFFH_01291 6.2e-210 S Esterase-like activity of phytase
HAPJLFFH_01292 3.3e-87 xynX5 3.1.4.46, 3.2.1.8 I PAP2 superfamily
HAPJLFFH_01293 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAPJLFFH_01294 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAPJLFFH_01295 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HAPJLFFH_01296 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAPJLFFH_01298 8.5e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
HAPJLFFH_01299 5.4e-228 M Glycosyl transferase 4-like domain
HAPJLFFH_01300 0.0 M Parallel beta-helix repeats
HAPJLFFH_01301 3.7e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HAPJLFFH_01302 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HAPJLFFH_01303 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HAPJLFFH_01304 3.3e-110
HAPJLFFH_01305 2.1e-93 S Protein of unknown function (DUF4230)
HAPJLFFH_01306 1.3e-151 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
HAPJLFFH_01307 8.9e-33 K DNA-binding transcription factor activity
HAPJLFFH_01308 4.7e-69 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAPJLFFH_01309 2e-32
HAPJLFFH_01310 5.5e-305 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
HAPJLFFH_01311 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HAPJLFFH_01312 6.8e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HAPJLFFH_01313 5e-240 purD 6.3.4.13 F Belongs to the GARS family
HAPJLFFH_01314 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HAPJLFFH_01315 1e-246 S Putative esterase
HAPJLFFH_01316 0.0 lysX S Uncharacterised conserved protein (DUF2156)
HAPJLFFH_01318 1.1e-161 P Zinc-uptake complex component A periplasmic
HAPJLFFH_01319 1.3e-128 S cobalamin synthesis protein
HAPJLFFH_01320 3e-46 rpmB J Ribosomal L28 family
HAPJLFFH_01321 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAPJLFFH_01322 2.2e-41 rpmE2 J Ribosomal protein L31
HAPJLFFH_01323 8.2e-15 rpmJ J Ribosomal protein L36
HAPJLFFH_01324 4.3e-22 J Ribosomal L32p protein family
HAPJLFFH_01325 9e-201 ycgR S Predicted permease
HAPJLFFH_01326 7.7e-154 S TIGRFAM TIGR03943 family protein
HAPJLFFH_01327 9.8e-45
HAPJLFFH_01328 4.3e-73 zur P Belongs to the Fur family
HAPJLFFH_01329 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HAPJLFFH_01330 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HAPJLFFH_01331 8.5e-179 adh3 C Zinc-binding dehydrogenase
HAPJLFFH_01332 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAPJLFFH_01334 1.4e-44 S Memo-like protein
HAPJLFFH_01335 1e-229 K Putative ATP-dependent DNA helicase recG C-terminal
HAPJLFFH_01336 2.7e-160 K Helix-turn-helix domain, rpiR family
HAPJLFFH_01337 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HAPJLFFH_01338 2.3e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
HAPJLFFH_01339 2e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAPJLFFH_01340 2.6e-269 yhdG E aromatic amino acid transport protein AroP K03293
HAPJLFFH_01341 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HAPJLFFH_01342 2.1e-31 J Acetyltransferase (GNAT) domain
HAPJLFFH_01343 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HAPJLFFH_01344 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HAPJLFFH_01345 2.2e-221 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HAPJLFFH_01346 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HAPJLFFH_01347 4.4e-109
HAPJLFFH_01348 1.7e-187 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAPJLFFH_01349 4.8e-154 sapF E ATPases associated with a variety of cellular activities
HAPJLFFH_01350 2.6e-141 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
HAPJLFFH_01351 2.4e-162 EP Binding-protein-dependent transport system inner membrane component
HAPJLFFH_01352 1.6e-169 P Binding-protein-dependent transport system inner membrane component
HAPJLFFH_01353 1.8e-309 E ABC transporter, substrate-binding protein, family 5
HAPJLFFH_01354 1.8e-142 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAPJLFFH_01355 2e-277 G Bacterial extracellular solute-binding protein
HAPJLFFH_01356 3.3e-62 G carbohydrate transport
HAPJLFFH_01357 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HAPJLFFH_01358 5.5e-124 G ABC transporter permease
HAPJLFFH_01359 6.6e-190 K Periplasmic binding protein domain
HAPJLFFH_01360 1.4e-17 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HAPJLFFH_01361 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
HAPJLFFH_01362 1.1e-17 L Helix-turn-helix domain
HAPJLFFH_01363 4.4e-18 S Protein of unknown function (DUF2442)
HAPJLFFH_01364 2.6e-16 K Helix-turn-helix domain
HAPJLFFH_01365 2.9e-107 L Belongs to the 'phage' integrase family
HAPJLFFH_01366 1.5e-78 hsdS 2.1.1.72, 3.1.21.3 L Type I restriction modification DNA specificity domain
HAPJLFFH_01367 1.2e-243 hsdM 2.1.1.72 V HsdM N-terminal domain
HAPJLFFH_01368 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HAPJLFFH_01369 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAPJLFFH_01370 3.8e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HAPJLFFH_01371 3e-273 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
HAPJLFFH_01372 3.5e-126 XK27_08050 O prohibitin homologues
HAPJLFFH_01373 9.9e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
HAPJLFFH_01374 9.8e-233 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HAPJLFFH_01375 2.8e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
HAPJLFFH_01376 1.8e-226 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HAPJLFFH_01377 3e-112 macB_2 V ATPases associated with a variety of cellular activities
HAPJLFFH_01378 0.0 ctpE P E1-E2 ATPase
HAPJLFFH_01379 6.4e-54 racA K MerR, DNA binding
HAPJLFFH_01380 3.2e-197 yghZ C Aldo/keto reductase family
HAPJLFFH_01381 7.4e-100 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HAPJLFFH_01382 7.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HAPJLFFH_01383 5.5e-149 map 3.4.11.18 E Methionine aminopeptidase
HAPJLFFH_01384 8.8e-122 S Short repeat of unknown function (DUF308)
HAPJLFFH_01385 0.0 pepO 3.4.24.71 O Peptidase family M13
HAPJLFFH_01386 1.6e-120 L Single-strand binding protein family
HAPJLFFH_01387 8.8e-90
HAPJLFFH_01388 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HAPJLFFH_01391 1.4e-270 recD2 3.6.4.12 L PIF1-like helicase
HAPJLFFH_01392 8.4e-159 supH S Sucrose-6F-phosphate phosphohydrolase
HAPJLFFH_01393 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HAPJLFFH_01394 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HAPJLFFH_01395 3.5e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HAPJLFFH_01396 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HAPJLFFH_01397 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
HAPJLFFH_01398 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HAPJLFFH_01399 1.5e-186 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HAPJLFFH_01400 4.5e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAPJLFFH_01401 3.9e-36 rpmE J Binds the 23S rRNA
HAPJLFFH_01403 2.1e-188 K helix_turn_helix, arabinose operon control protein
HAPJLFFH_01404 2.6e-163 glcU G Sugar transport protein
HAPJLFFH_01405 2.9e-174 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HAPJLFFH_01406 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
HAPJLFFH_01407 1.5e-108
HAPJLFFH_01408 8.3e-170 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
HAPJLFFH_01409 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
HAPJLFFH_01410 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HAPJLFFH_01411 4.2e-164 EG EamA-like transporter family
HAPJLFFH_01413 7.8e-53 V FtsX-like permease family
HAPJLFFH_01414 5.9e-147 S Sulfite exporter TauE/SafE
HAPJLFFH_01416 1.6e-28 L Transposase
HAPJLFFH_01417 3.4e-216 MA20_36090 S Psort location Cytoplasmic, score 8.87
HAPJLFFH_01418 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
HAPJLFFH_01419 2.1e-35 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
HAPJLFFH_01420 1.2e-72 EGP Major facilitator superfamily
HAPJLFFH_01421 3.7e-179 glkA 2.7.1.2 G ROK family
HAPJLFFH_01422 4.2e-242 S ATPases associated with a variety of cellular activities
HAPJLFFH_01423 1.2e-55 EGP Major facilitator Superfamily
HAPJLFFH_01424 1.1e-158 I alpha/beta hydrolase fold
HAPJLFFH_01425 8.2e-111 S Pyridoxamine 5'-phosphate oxidase
HAPJLFFH_01427 5.2e-61 S DUF218 domain
HAPJLFFH_01428 6.6e-34 S DUF218 domain
HAPJLFFH_01429 5e-13 S Protein of unknown function (DUF979)
HAPJLFFH_01430 4.4e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HAPJLFFH_01431 2e-126
HAPJLFFH_01432 5.5e-153 M domain, Protein
HAPJLFFH_01433 1.3e-10 M domain, Protein
HAPJLFFH_01434 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
HAPJLFFH_01435 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
HAPJLFFH_01436 7.1e-172 tesB I Thioesterase-like superfamily
HAPJLFFH_01437 1.3e-77 S Protein of unknown function (DUF3180)
HAPJLFFH_01438 2.7e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAPJLFFH_01439 2.3e-164 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HAPJLFFH_01440 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HAPJLFFH_01441 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAPJLFFH_01442 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HAPJLFFH_01443 2.1e-213 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HAPJLFFH_01444 4.5e-261 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
HAPJLFFH_01445 5e-309
HAPJLFFH_01446 1.7e-168 natA V ATPases associated with a variety of cellular activities
HAPJLFFH_01447 1.3e-232 epsG M Glycosyl transferase family 21
HAPJLFFH_01448 3.9e-274 S AI-2E family transporter
HAPJLFFH_01449 1.9e-177 3.4.14.13 M Glycosyltransferase like family 2
HAPJLFFH_01450 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
HAPJLFFH_01453 2.6e-68 S Domain of unknown function (DUF4190)
HAPJLFFH_01454 2.6e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HAPJLFFH_01455 1.1e-175 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HAPJLFFH_01457 1.6e-17 S Transcription factor WhiB
HAPJLFFH_01458 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
HAPJLFFH_01459 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HAPJLFFH_01460 2.8e-85 nagA 3.5.1.25 G Amidohydrolase family
HAPJLFFH_01461 1.3e-179 lacR K Transcriptional regulator, LacI family
HAPJLFFH_01462 2.1e-194 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HAPJLFFH_01463 3.9e-119 K Transcriptional regulatory protein, C terminal
HAPJLFFH_01464 4.8e-101
HAPJLFFH_01465 4.1e-144 L IstB-like ATP binding protein
HAPJLFFH_01466 5.8e-296 L PFAM Integrase catalytic
HAPJLFFH_01467 1.9e-148 V N-Acetylmuramoyl-L-alanine amidase
HAPJLFFH_01468 7.4e-109 ytrE V ABC transporter
HAPJLFFH_01469 1.5e-171
HAPJLFFH_01471 1.1e-219 vex3 V ABC transporter permease
HAPJLFFH_01472 4.7e-211 vex1 V Efflux ABC transporter, permease protein
HAPJLFFH_01473 1.3e-111 vex2 V ABC transporter, ATP-binding protein
HAPJLFFH_01474 9.4e-23 azlD E Branched-chain amino acid transport protein (AzlD)
HAPJLFFH_01475 3.7e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
HAPJLFFH_01476 4e-95 ptpA 3.1.3.48 T low molecular weight
HAPJLFFH_01477 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
HAPJLFFH_01478 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAPJLFFH_01479 3.8e-72 attW O OsmC-like protein
HAPJLFFH_01480 1.6e-191 T Universal stress protein family
HAPJLFFH_01481 2.4e-107 M NlpC/P60 family
HAPJLFFH_01482 6.3e-177 usp 3.5.1.28 CBM50 S CHAP domain
HAPJLFFH_01483 2.5e-214 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HAPJLFFH_01484 2.6e-39
HAPJLFFH_01485 1.3e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPJLFFH_01486 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
HAPJLFFH_01487 1e-09 EGP Major facilitator Superfamily
HAPJLFFH_01488 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAPJLFFH_01489 4.7e-174 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HAPJLFFH_01490 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HAPJLFFH_01492 1.6e-216 araJ EGP Major facilitator Superfamily
HAPJLFFH_01493 0.0 S Domain of unknown function (DUF4037)
HAPJLFFH_01494 1.5e-112 S Protein of unknown function (DUF4125)
HAPJLFFH_01495 8.5e-131
HAPJLFFH_01496 9.2e-285 pspC KT PspC domain
HAPJLFFH_01497 8.9e-273 tcsS3 KT PspC domain
HAPJLFFH_01498 9.2e-126 degU K helix_turn_helix, Lux Regulon
HAPJLFFH_01499 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAPJLFFH_01501 2.5e-141 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HAPJLFFH_01502 5.8e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
HAPJLFFH_01503 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAPJLFFH_01504 1e-93
HAPJLFFH_01506 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
HAPJLFFH_01508 3.3e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAPJLFFH_01509 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
HAPJLFFH_01510 6.7e-212 I Diacylglycerol kinase catalytic domain
HAPJLFFH_01511 3.2e-150 arbG K CAT RNA binding domain
HAPJLFFH_01512 0.0 crr G pts system, glucose-specific IIABC component
HAPJLFFH_01513 1.9e-29 M Spy0128-like isopeptide containing domain
HAPJLFFH_01514 2.7e-43 M Spy0128-like isopeptide containing domain
HAPJLFFH_01515 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HAPJLFFH_01516 5.8e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HAPJLFFH_01517 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
HAPJLFFH_01518 1.2e-202 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAPJLFFH_01519 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HAPJLFFH_01521 3.6e-106
HAPJLFFH_01522 1.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HAPJLFFH_01523 2.1e-230 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HAPJLFFH_01524 3.9e-232 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAPJLFFH_01525 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAPJLFFH_01526 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAPJLFFH_01527 2.8e-188 nusA K Participates in both transcription termination and antitermination
HAPJLFFH_01528 3e-160
HAPJLFFH_01529 7.5e-131 L Transposase and inactivated derivatives
HAPJLFFH_01531 5e-153 E Transglutaminase/protease-like homologues
HAPJLFFH_01532 0.0 gcs2 S A circularly permuted ATPgrasp
HAPJLFFH_01533 9.2e-172 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HAPJLFFH_01534 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
HAPJLFFH_01535 2.8e-64 rplQ J Ribosomal protein L17
HAPJLFFH_01536 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPJLFFH_01537 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAPJLFFH_01538 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAPJLFFH_01539 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HAPJLFFH_01540 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAPJLFFH_01541 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HAPJLFFH_01542 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HAPJLFFH_01543 2.7e-63 rplO J binds to the 23S rRNA
HAPJLFFH_01544 1e-24 rpmD J Ribosomal protein L30p/L7e
HAPJLFFH_01545 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAPJLFFH_01546 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAPJLFFH_01547 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAPJLFFH_01548 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAPJLFFH_01549 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAPJLFFH_01550 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAPJLFFH_01551 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAPJLFFH_01552 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAPJLFFH_01553 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAPJLFFH_01554 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
HAPJLFFH_01555 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAPJLFFH_01556 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAPJLFFH_01557 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAPJLFFH_01558 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAPJLFFH_01559 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAPJLFFH_01560 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HAPJLFFH_01561 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
HAPJLFFH_01562 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAPJLFFH_01563 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
HAPJLFFH_01564 7.9e-97 ywiC S YwiC-like protein
HAPJLFFH_01565 2.3e-156 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HAPJLFFH_01566 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HAPJLFFH_01567 1.9e-233 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HAPJLFFH_01568 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HAPJLFFH_01569 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
HAPJLFFH_01570 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAPJLFFH_01571 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HAPJLFFH_01572 3.3e-119
HAPJLFFH_01573 1.8e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HAPJLFFH_01574 3.6e-257 M Bacterial capsule synthesis protein PGA_cap
HAPJLFFH_01576 1.4e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAPJLFFH_01577 1.4e-223 dapC E Aminotransferase class I and II
HAPJLFFH_01578 7.6e-60 fdxA C 4Fe-4S binding domain
HAPJLFFH_01579 1e-213 murB 1.3.1.98 M Cell wall formation
HAPJLFFH_01580 1.9e-25 rpmG J Ribosomal protein L33
HAPJLFFH_01584 4.6e-43 moxR S ATPase family associated with various cellular activities (AAA)
HAPJLFFH_01585 1.5e-130 bla1 3.5.2.6 V Beta-lactamase enzyme family
HAPJLFFH_01586 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAPJLFFH_01587 2e-141
HAPJLFFH_01588 2.3e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
HAPJLFFH_01589 2e-120 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HAPJLFFH_01590 3.2e-38 fmdB S Putative regulatory protein
HAPJLFFH_01591 5.6e-110 flgA NO SAF
HAPJLFFH_01592 9.6e-42
HAPJLFFH_01593 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HAPJLFFH_01594 4.7e-246 T Forkhead associated domain
HAPJLFFH_01596 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HAPJLFFH_01597 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAPJLFFH_01598 1.9e-181 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
HAPJLFFH_01599 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
HAPJLFFH_01601 8.8e-222 pbuO S Permease family
HAPJLFFH_01602 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAPJLFFH_01603 1.9e-167 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HAPJLFFH_01604 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAPJLFFH_01605 1.4e-179 pstA P Phosphate transport system permease
HAPJLFFH_01606 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
HAPJLFFH_01607 2.3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HAPJLFFH_01608 3.7e-128 KT Transcriptional regulatory protein, C terminal
HAPJLFFH_01609 5.5e-245 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HAPJLFFH_01610 4.3e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HAPJLFFH_01611 4.4e-283 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAPJLFFH_01612 9.1e-107 K helix_turn_helix, Arsenical Resistance Operon Repressor
HAPJLFFH_01613 3.1e-243 EGP Major facilitator Superfamily
HAPJLFFH_01614 5.6e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HAPJLFFH_01615 1.4e-168 L Excalibur calcium-binding domain
HAPJLFFH_01616 3.2e-269 pepC 3.4.22.40 E Peptidase C1-like family
HAPJLFFH_01617 7.6e-46 D nuclear chromosome segregation
HAPJLFFH_01618 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HAPJLFFH_01619 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HAPJLFFH_01620 1.8e-187 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HAPJLFFH_01621 0.0 yegQ O Peptidase family U32 C-terminal domain
HAPJLFFH_01622 2.9e-96 L Transposase and inactivated derivatives IS30 family
HAPJLFFH_01623 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HAPJLFFH_01624 1.4e-40 nrdH O Glutaredoxin
HAPJLFFH_01625 1.9e-98 nrdI F Probably involved in ribonucleotide reductase function
HAPJLFFH_01626 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAPJLFFH_01627 7e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAPJLFFH_01628 3.2e-77 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HAPJLFFH_01629 0.0 S Predicted membrane protein (DUF2207)
HAPJLFFH_01630 9.6e-90 lemA S LemA family
HAPJLFFH_01631 2.3e-41 K purine nucleotide biosynthetic process
HAPJLFFH_01632 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HAPJLFFH_01633 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAPJLFFH_01634 4.9e-117
HAPJLFFH_01635 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
HAPJLFFH_01637 1.6e-160 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HAPJLFFH_01638 3.2e-98 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HAPJLFFH_01639 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HAPJLFFH_01640 7.2e-308 pccB I Carboxyl transferase domain
HAPJLFFH_01641 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HAPJLFFH_01642 2.1e-92 bioY S BioY family
HAPJLFFH_01643 6.4e-151 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HAPJLFFH_01644 0.0
HAPJLFFH_01645 1e-145 QT PucR C-terminal helix-turn-helix domain
HAPJLFFH_01646 1e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HAPJLFFH_01647 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HAPJLFFH_01648 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAPJLFFH_01649 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAPJLFFH_01650 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAPJLFFH_01651 2.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAPJLFFH_01652 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAPJLFFH_01653 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAPJLFFH_01654 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
HAPJLFFH_01655 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAPJLFFH_01657 4.6e-35
HAPJLFFH_01658 0.0 K RNA polymerase II activating transcription factor binding
HAPJLFFH_01659 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HAPJLFFH_01660 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HAPJLFFH_01663 3.2e-101 mntP P Probably functions as a manganese efflux pump
HAPJLFFH_01664 1.4e-125
HAPJLFFH_01665 2e-135 KT Transcriptional regulatory protein, C terminal
HAPJLFFH_01666 3e-127 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAPJLFFH_01667 1.9e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
HAPJLFFH_01668 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HAPJLFFH_01669 0.0 S domain protein
HAPJLFFH_01670 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
HAPJLFFH_01671 1.5e-89 lrp_3 K helix_turn_helix ASNC type
HAPJLFFH_01672 4.7e-235 E Aminotransferase class I and II
HAPJLFFH_01673 9.2e-308 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAPJLFFH_01674 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
HAPJLFFH_01675 2.5e-52 S Protein of unknown function (DUF2469)
HAPJLFFH_01676 6.6e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
HAPJLFFH_01677 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAPJLFFH_01678 9.2e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HAPJLFFH_01679 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAPJLFFH_01680 1e-60 V ABC transporter
HAPJLFFH_01681 9.6e-59 V ABC transporter
HAPJLFFH_01682 2.8e-157 spoU 2.1.1.185 J RNA methyltransferase TrmH family
HAPJLFFH_01683 7.2e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAPJLFFH_01684 3.4e-199 rmuC S RmuC family
HAPJLFFH_01685 1.4e-42 csoR S Metal-sensitive transcriptional repressor
HAPJLFFH_01686 0.0 pacS 3.6.3.54 P E1-E2 ATPase
HAPJLFFH_01687 0.0 ubiB S ABC1 family
HAPJLFFH_01688 3.5e-19 S granule-associated protein
HAPJLFFH_01689 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HAPJLFFH_01690 1.4e-279 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HAPJLFFH_01691 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HAPJLFFH_01692 1.2e-250 dinF V MatE
HAPJLFFH_01693 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HAPJLFFH_01694 1e-54 glnB K Nitrogen regulatory protein P-II
HAPJLFFH_01695 8.5e-219 amt U Ammonium Transporter Family
HAPJLFFH_01696 8.1e-203 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HAPJLFFH_01698 2.7e-116 icaR K Bacterial regulatory proteins, tetR family
HAPJLFFH_01699 6.6e-198 XK27_01805 M Glycosyltransferase like family 2
HAPJLFFH_01700 0.0 S Glycosyl hydrolases related to GH101 family, GH129
HAPJLFFH_01701 3.5e-304 pepD E Peptidase family C69
HAPJLFFH_01702 2.2e-12 XK27_08585 S Hypothetical bacterial integral membrane protein (Trep_Strep)
HAPJLFFH_01703 9.8e-88 XK26_04485 P Cobalt transport protein
HAPJLFFH_01704 1e-83
HAPJLFFH_01705 0.0 V ABC transporter transmembrane region
HAPJLFFH_01706 1.8e-301 V ABC transporter, ATP-binding protein
HAPJLFFH_01707 2.7e-82 K Winged helix DNA-binding domain
HAPJLFFH_01708 5.8e-305 M LPXTG cell wall anchor motif
HAPJLFFH_01709 7.6e-197 M chlorophyll binding
HAPJLFFH_01710 4.2e-206 M chlorophyll binding
HAPJLFFH_01711 2e-180 3.4.22.70 M Sortase family
HAPJLFFH_01713 5.2e-161 S Sucrose-6F-phosphate phosphohydrolase
HAPJLFFH_01714 2.3e-240 S Putative ABC-transporter type IV
HAPJLFFH_01715 7e-81
HAPJLFFH_01716 6.2e-35 Q phosphatase activity
HAPJLFFH_01717 1.2e-295 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
HAPJLFFH_01718 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HAPJLFFH_01719 1.2e-48 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HAPJLFFH_01720 2.1e-249 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAPJLFFH_01721 4.6e-67 S haloacid dehalogenase-like hydrolase
HAPJLFFH_01722 3.6e-131 yydK K UTRA
HAPJLFFH_01723 1.3e-70 S FMN_bind
HAPJLFFH_01724 5.7e-149 macB V ABC transporter, ATP-binding protein
HAPJLFFH_01725 2.6e-204 Z012_06715 V FtsX-like permease family
HAPJLFFH_01726 4.8e-222 macB_2 V ABC transporter permease
HAPJLFFH_01727 5.4e-234 S Predicted membrane protein (DUF2318)
HAPJLFFH_01728 1.8e-106 tpd P Fe2+ transport protein
HAPJLFFH_01729 1e-307 efeU_1 P Iron permease FTR1 family
HAPJLFFH_01730 6.9e-23 G MFS/sugar transport protein
HAPJLFFH_01731 1.7e-198 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAPJLFFH_01732 1.9e-57 S Fic/DOC family
HAPJLFFH_01733 1.3e-32 S Fic/DOC family
HAPJLFFH_01734 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAPJLFFH_01735 1.9e-37 ptsH G PTS HPr component phosphorylation site
HAPJLFFH_01736 4.4e-200 K helix_turn _helix lactose operon repressor
HAPJLFFH_01737 6.3e-213 holB 2.7.7.7 L DNA polymerase III
HAPJLFFH_01738 1.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAPJLFFH_01739 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAPJLFFH_01740 2.3e-188 3.6.1.27 I PAP2 superfamily
HAPJLFFH_01741 0.0 vpr M PA domain
HAPJLFFH_01742 6.8e-122 yplQ S Haemolysin-III related
HAPJLFFH_01743 2.4e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
HAPJLFFH_01744 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HAPJLFFH_01745 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HAPJLFFH_01746 1.9e-280 S Calcineurin-like phosphoesterase
HAPJLFFH_01747 3e-15 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HAPJLFFH_01748 1.3e-281 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HAPJLFFH_01749 1.7e-116
HAPJLFFH_01750 2.6e-213 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAPJLFFH_01751 1.8e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
HAPJLFFH_01752 5.3e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HAPJLFFH_01753 1.1e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAPJLFFH_01754 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HAPJLFFH_01755 3.7e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
HAPJLFFH_01756 6.9e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
HAPJLFFH_01757 5.4e-41 S Protein of unknown function (DUF4244)
HAPJLFFH_01758 7.1e-15 gspF NU Type II secretion system (T2SS), protein F
HAPJLFFH_01759 1.4e-14 gspF NU Type II secretion system (T2SS), protein F
HAPJLFFH_01760 2.8e-120 U Type ii secretion system
HAPJLFFH_01761 9.8e-191 cpaF U Type II IV secretion system protein
HAPJLFFH_01762 1.3e-151 cpaE D bacterial-type flagellum organization
HAPJLFFH_01763 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAPJLFFH_01764 2.2e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HAPJLFFH_01765 7.2e-98
HAPJLFFH_01767 5e-57 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HAPJLFFH_01768 5e-209 S Glycosyltransferase, group 2 family protein
HAPJLFFH_01769 2e-277
HAPJLFFH_01770 8.7e-27 thiS 2.8.1.10 H ThiS family
HAPJLFFH_01771 5.4e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HAPJLFFH_01772 0.0 S Psort location Cytoplasmic, score 8.87
HAPJLFFH_01773 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
HAPJLFFH_01774 1.1e-246 V ABC transporter permease
HAPJLFFH_01775 3.2e-181 V ABC transporter
HAPJLFFH_01776 2.1e-137 T HD domain
HAPJLFFH_01777 2.3e-164 S Glutamine amidotransferase domain
HAPJLFFH_01778 0.0 kup P Transport of potassium into the cell
HAPJLFFH_01779 3.8e-184 tatD L TatD related DNase
HAPJLFFH_01780 4.5e-209 xylR 5.3.1.12 G MFS/sugar transport protein
HAPJLFFH_01781 6e-25 G Bacterial extracellular solute-binding protein
HAPJLFFH_01782 2.9e-79 K Transcriptional regulator
HAPJLFFH_01783 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAPJLFFH_01784 1.6e-130
HAPJLFFH_01785 8.6e-59
HAPJLFFH_01786 4.4e-167 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HAPJLFFH_01787 5.9e-126 dedA S SNARE associated Golgi protein
HAPJLFFH_01789 3.5e-134 S HAD hydrolase, family IA, variant 3
HAPJLFFH_01790 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
HAPJLFFH_01791 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
HAPJLFFH_01792 2.6e-86 hspR K transcriptional regulator, MerR family
HAPJLFFH_01793 2.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
HAPJLFFH_01795 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAPJLFFH_01796 0.0 dnaK O Heat shock 70 kDa protein
HAPJLFFH_01797 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
HAPJLFFH_01798 2.9e-190 K Psort location Cytoplasmic, score
HAPJLFFH_01801 1.8e-138 G Phosphoglycerate mutase family
HAPJLFFH_01802 8e-70 S Protein of unknown function (DUF4235)
HAPJLFFH_01803 1.6e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HAPJLFFH_01804 1.1e-45
HAPJLFFH_01805 6.2e-156 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
HAPJLFFH_01806 8.8e-15 S COG NOG14600 non supervised orthologous group
HAPJLFFH_01807 1.3e-143 cobB2 K Sir2 family
HAPJLFFH_01808 2.2e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HAPJLFFH_01809 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HAPJLFFH_01810 4.7e-145 ypfH S Phospholipase/Carboxylesterase
HAPJLFFH_01811 0.0 yjcE P Sodium/hydrogen exchanger family
HAPJLFFH_01812 1.2e-111 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HAPJLFFH_01813 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HAPJLFFH_01814 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HAPJLFFH_01816 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAPJLFFH_01817 9.8e-261 KLT Domain of unknown function (DUF4032)
HAPJLFFH_01818 5.4e-145
HAPJLFFH_01819 2e-180 3.4.22.70 M Sortase family
HAPJLFFH_01820 1.7e-229 M LPXTG-motif cell wall anchor domain protein
HAPJLFFH_01821 0.0 S LPXTG-motif cell wall anchor domain protein
HAPJLFFH_01822 3.7e-99 L Helix-turn-helix domain
HAPJLFFH_01823 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
HAPJLFFH_01824 8.4e-173 K Psort location Cytoplasmic, score
HAPJLFFH_01825 0.0 KLT Protein tyrosine kinase
HAPJLFFH_01826 2.4e-150 O Thioredoxin
HAPJLFFH_01828 3.6e-213 S G5
HAPJLFFH_01829 4.1e-170 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HAPJLFFH_01830 7.9e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HAPJLFFH_01831 2e-112 S LytR cell envelope-related transcriptional attenuator
HAPJLFFH_01832 9.5e-280 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HAPJLFFH_01833 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HAPJLFFH_01834 0.0 M Conserved repeat domain
HAPJLFFH_01835 0.0 murJ KLT MviN-like protein
HAPJLFFH_01836 1.4e-204 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HAPJLFFH_01837 4.7e-244 parB K Belongs to the ParB family
HAPJLFFH_01838 3.8e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HAPJLFFH_01839 2.1e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HAPJLFFH_01840 6.5e-93 jag S Putative single-stranded nucleic acids-binding domain
HAPJLFFH_01841 1.9e-170 yidC U Membrane protein insertase, YidC Oxa1 family
HAPJLFFH_01842 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)