ORF_ID e_value Gene_name EC_number CAZy COGs Description
PMLHKFCF_00001 2.1e-29 K Bacterial regulatory proteins, tetR family
PMLHKFCF_00002 2.1e-241 npr 1.11.1.1 C NADH oxidase
PMLHKFCF_00003 0.0
PMLHKFCF_00004 3.5e-61
PMLHKFCF_00005 9.3e-192 S Fn3-like domain
PMLHKFCF_00006 4e-103 S WxL domain surface cell wall-binding
PMLHKFCF_00007 3.5e-78 S WxL domain surface cell wall-binding
PMLHKFCF_00008 7.8e-121 draG 3.2.2.24 O ADP-ribosylglycohydrolase
PMLHKFCF_00009 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PMLHKFCF_00010 2e-42
PMLHKFCF_00011 9.9e-82 hit FG histidine triad
PMLHKFCF_00012 1.6e-134 ecsA V ABC transporter, ATP-binding protein
PMLHKFCF_00013 6.2e-224 ecsB U ABC transporter
PMLHKFCF_00014 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
PMLHKFCF_00015 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
PMLHKFCF_00016 7.4e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PMLHKFCF_00017 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
PMLHKFCF_00018 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PMLHKFCF_00019 7.9e-21 S Virus attachment protein p12 family
PMLHKFCF_00020 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PMLHKFCF_00021 1.3e-34 feoA P FeoA domain
PMLHKFCF_00022 4.2e-144 sufC O FeS assembly ATPase SufC
PMLHKFCF_00023 2.6e-244 sufD O FeS assembly protein SufD
PMLHKFCF_00024 8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PMLHKFCF_00025 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
PMLHKFCF_00026 1.4e-272 sufB O assembly protein SufB
PMLHKFCF_00027 5.5e-45 yitW S Iron-sulfur cluster assembly protein
PMLHKFCF_00028 3.1e-111 hipB K Helix-turn-helix
PMLHKFCF_00029 4.5e-121 ybhL S Belongs to the BI1 family
PMLHKFCF_00030 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PMLHKFCF_00031 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PMLHKFCF_00032 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PMLHKFCF_00033 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PMLHKFCF_00034 1.1e-248 dnaB L replication initiation and membrane attachment
PMLHKFCF_00035 1.2e-171 dnaI L Primosomal protein DnaI
PMLHKFCF_00036 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PMLHKFCF_00037 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PMLHKFCF_00038 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PMLHKFCF_00039 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PMLHKFCF_00040 1.1e-55
PMLHKFCF_00041 5e-240 yrvN L AAA C-terminal domain
PMLHKFCF_00042 8e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PMLHKFCF_00043 1e-62 hxlR K Transcriptional regulator, HxlR family
PMLHKFCF_00044 2.2e-134 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
PMLHKFCF_00045 2.4e-238 pgaC GT2 M Glycosyl transferase
PMLHKFCF_00046 1.3e-79
PMLHKFCF_00047 1.4e-98 yqeG S HAD phosphatase, family IIIA
PMLHKFCF_00048 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
PMLHKFCF_00049 1.1e-50 yhbY J RNA-binding protein
PMLHKFCF_00050 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PMLHKFCF_00051 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PMLHKFCF_00052 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PMLHKFCF_00053 4.4e-140 yqeM Q Methyltransferase
PMLHKFCF_00054 3.4e-219 ylbM S Belongs to the UPF0348 family
PMLHKFCF_00055 1.6e-97 yceD S Uncharacterized ACR, COG1399
PMLHKFCF_00056 7e-88 S Peptidase propeptide and YPEB domain
PMLHKFCF_00057 2e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PMLHKFCF_00058 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PMLHKFCF_00059 1.2e-244 rarA L recombination factor protein RarA
PMLHKFCF_00060 4.3e-121 K response regulator
PMLHKFCF_00061 8e-307 arlS 2.7.13.3 T Histidine kinase
PMLHKFCF_00062 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PMLHKFCF_00063 0.0 sbcC L Putative exonuclease SbcCD, C subunit
PMLHKFCF_00064 1.7e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PMLHKFCF_00065 9.3e-93 S SdpI/YhfL protein family
PMLHKFCF_00066 5.9e-150 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PMLHKFCF_00067 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PMLHKFCF_00068 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMLHKFCF_00069 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PMLHKFCF_00070 1.1e-62 yodB K Transcriptional regulator, HxlR family
PMLHKFCF_00071 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PMLHKFCF_00072 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PMLHKFCF_00073 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PMLHKFCF_00074 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
PMLHKFCF_00075 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PMLHKFCF_00076 2.3e-96 liaI S membrane
PMLHKFCF_00077 4e-75 XK27_02470 K LytTr DNA-binding domain
PMLHKFCF_00078 1.5e-54 yneR S Belongs to the HesB IscA family
PMLHKFCF_00079 0.0 S membrane
PMLHKFCF_00080 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PMLHKFCF_00081 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PMLHKFCF_00082 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PMLHKFCF_00083 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
PMLHKFCF_00084 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
PMLHKFCF_00085 5.7e-180 glk 2.7.1.2 G Glucokinase
PMLHKFCF_00086 6.4e-111 pepE 3.4.13.21 E Belongs to the peptidase S51 family
PMLHKFCF_00087 4.4e-68 yqhL P Rhodanese-like protein
PMLHKFCF_00088 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
PMLHKFCF_00089 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
PMLHKFCF_00090 1.6e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PMLHKFCF_00091 4.6e-64 glnR K Transcriptional regulator
PMLHKFCF_00092 3.1e-264 glnA 6.3.1.2 E glutamine synthetase
PMLHKFCF_00093 5.5e-161
PMLHKFCF_00094 4e-181
PMLHKFCF_00095 2.4e-98 dut S Protein conserved in bacteria
PMLHKFCF_00096 5.3e-56
PMLHKFCF_00097 1.7e-30
PMLHKFCF_00100 5.4e-19
PMLHKFCF_00101 1.8e-89 K Transcriptional regulator
PMLHKFCF_00102 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PMLHKFCF_00103 3.2e-53 ysxB J Cysteine protease Prp
PMLHKFCF_00104 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PMLHKFCF_00105 3.8e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PMLHKFCF_00106 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PMLHKFCF_00107 3.5e-74 yqhY S Asp23 family, cell envelope-related function
PMLHKFCF_00108 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PMLHKFCF_00109 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PMLHKFCF_00110 7.9e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PMLHKFCF_00111 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PMLHKFCF_00112 5.5e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PMLHKFCF_00113 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PMLHKFCF_00114 2.2e-76 argR K Regulates arginine biosynthesis genes
PMLHKFCF_00115 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
PMLHKFCF_00116 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
PMLHKFCF_00117 1.2e-104 opuCB E ABC transporter permease
PMLHKFCF_00118 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PMLHKFCF_00119 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
PMLHKFCF_00120 4.5e-55
PMLHKFCF_00121 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PMLHKFCF_00122 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PMLHKFCF_00123 8.8e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PMLHKFCF_00124 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PMLHKFCF_00125 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PMLHKFCF_00126 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PMLHKFCF_00127 1.7e-134 stp 3.1.3.16 T phosphatase
PMLHKFCF_00128 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PMLHKFCF_00129 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PMLHKFCF_00130 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PMLHKFCF_00131 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
PMLHKFCF_00132 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PMLHKFCF_00133 1.8e-57 asp S Asp23 family, cell envelope-related function
PMLHKFCF_00134 0.0 yloV S DAK2 domain fusion protein YloV
PMLHKFCF_00135 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PMLHKFCF_00136 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PMLHKFCF_00137 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PMLHKFCF_00138 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PMLHKFCF_00139 0.0 smc D Required for chromosome condensation and partitioning
PMLHKFCF_00140 1.9e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PMLHKFCF_00141 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PMLHKFCF_00142 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PMLHKFCF_00143 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PMLHKFCF_00144 2.6e-39 ylqC S Belongs to the UPF0109 family
PMLHKFCF_00145 1.4e-39 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PMLHKFCF_00146 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PMLHKFCF_00147 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PMLHKFCF_00148 6.8e-53
PMLHKFCF_00149 6.4e-156 pelX UW LPXTG-motif cell wall anchor domain protein
PMLHKFCF_00150 5.3e-86
PMLHKFCF_00151 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
PMLHKFCF_00152 1.5e-270 XK27_00765
PMLHKFCF_00154 5.4e-267 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
PMLHKFCF_00155 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
PMLHKFCF_00156 1.2e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PMLHKFCF_00157 1.4e-128 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PMLHKFCF_00158 4.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
PMLHKFCF_00159 3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PMLHKFCF_00160 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PMLHKFCF_00161 2e-97 entB 3.5.1.19 Q Isochorismatase family
PMLHKFCF_00162 4.8e-165 1.6.5.5 C Zinc-binding dehydrogenase
PMLHKFCF_00163 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
PMLHKFCF_00164 5.8e-217 E glutamate:sodium symporter activity
PMLHKFCF_00165 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
PMLHKFCF_00166 5.1e-198 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PMLHKFCF_00167 2.1e-58 S Protein of unknown function (DUF1648)
PMLHKFCF_00169 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PMLHKFCF_00170 1.1e-178 yneE K Transcriptional regulator
PMLHKFCF_00171 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PMLHKFCF_00172 2.9e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PMLHKFCF_00173 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PMLHKFCF_00174 1.3e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PMLHKFCF_00175 2.1e-126 IQ reductase
PMLHKFCF_00176 1.4e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PMLHKFCF_00177 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PMLHKFCF_00178 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
PMLHKFCF_00179 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PMLHKFCF_00180 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PMLHKFCF_00181 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PMLHKFCF_00182 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PMLHKFCF_00183 1.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
PMLHKFCF_00184 2.2e-123 S Protein of unknown function (DUF554)
PMLHKFCF_00185 1.6e-160 K LysR substrate binding domain
PMLHKFCF_00186 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
PMLHKFCF_00187 1.9e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PMLHKFCF_00188 7.5e-92 K transcriptional regulator
PMLHKFCF_00189 1.4e-301 norB EGP Major Facilitator
PMLHKFCF_00190 1.2e-139 f42a O Band 7 protein
PMLHKFCF_00191 8.5e-54
PMLHKFCF_00192 1.3e-28
PMLHKFCF_00193 1.8e-207 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PMLHKFCF_00194 2.3e-29 L hmm pf00665
PMLHKFCF_00195 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
PMLHKFCF_00196 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
PMLHKFCF_00197 7.9e-41
PMLHKFCF_00198 1.9e-67 tspO T TspO/MBR family
PMLHKFCF_00199 6.3e-76 uspA T Belongs to the universal stress protein A family
PMLHKFCF_00200 1e-65 S Protein of unknown function (DUF805)
PMLHKFCF_00201 3.5e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
PMLHKFCF_00202 2.9e-35
PMLHKFCF_00203 3.1e-14
PMLHKFCF_00204 6.5e-41 S transglycosylase associated protein
PMLHKFCF_00205 4.8e-29 S CsbD-like
PMLHKFCF_00206 9.4e-40
PMLHKFCF_00207 8.6e-281 pipD E Dipeptidase
PMLHKFCF_00208 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PMLHKFCF_00209 2.7e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PMLHKFCF_00210 1.4e-170 2.5.1.74 H UbiA prenyltransferase family
PMLHKFCF_00211 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
PMLHKFCF_00212 1.9e-49
PMLHKFCF_00213 2.4e-43
PMLHKFCF_00214 3.3e-258 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PMLHKFCF_00215 1.4e-265 yfnA E Amino Acid
PMLHKFCF_00216 1.2e-149 yitU 3.1.3.104 S hydrolase
PMLHKFCF_00217 2.3e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PMLHKFCF_00218 1.5e-89 S Domain of unknown function (DUF4767)
PMLHKFCF_00219 2.5e-250 malT G Major Facilitator
PMLHKFCF_00220 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PMLHKFCF_00221 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PMLHKFCF_00222 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PMLHKFCF_00223 1.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PMLHKFCF_00224 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PMLHKFCF_00225 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PMLHKFCF_00226 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PMLHKFCF_00227 2.1e-72 ypmB S protein conserved in bacteria
PMLHKFCF_00228 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PMLHKFCF_00229 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PMLHKFCF_00230 1.1e-127 dnaD L Replication initiation and membrane attachment
PMLHKFCF_00232 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PMLHKFCF_00233 2e-99 metI P ABC transporter permease
PMLHKFCF_00234 2.1e-157 metQ_4 P Belongs to the nlpA lipoprotein family
PMLHKFCF_00235 4.4e-83 uspA T Universal stress protein family
PMLHKFCF_00236 1.2e-302 ftpA P Binding-protein-dependent transport system inner membrane component
PMLHKFCF_00237 4.9e-182 ftpB P Bacterial extracellular solute-binding protein
PMLHKFCF_00238 7e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
PMLHKFCF_00239 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PMLHKFCF_00240 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PMLHKFCF_00241 8.3e-110 ypsA S Belongs to the UPF0398 family
PMLHKFCF_00242 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PMLHKFCF_00244 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PMLHKFCF_00245 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
PMLHKFCF_00246 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
PMLHKFCF_00247 1.7e-72 S SnoaL-like domain
PMLHKFCF_00248 2.8e-241 M Glycosyltransferase, group 2 family protein
PMLHKFCF_00249 5.1e-209 mccF V LD-carboxypeptidase
PMLHKFCF_00250 1.4e-78 K Acetyltransferase (GNAT) domain
PMLHKFCF_00251 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PMLHKFCF_00252 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
PMLHKFCF_00253 1.1e-225 patA 2.6.1.1 E Aminotransferase
PMLHKFCF_00254 1.9e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PMLHKFCF_00255 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PMLHKFCF_00256 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
PMLHKFCF_00257 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PMLHKFCF_00258 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PMLHKFCF_00259 2.7e-39 ptsH G phosphocarrier protein HPR
PMLHKFCF_00260 6.5e-30
PMLHKFCF_00261 0.0 clpE O Belongs to the ClpA ClpB family
PMLHKFCF_00262 2.2e-73 L Integrase
PMLHKFCF_00263 1e-63 K Winged helix DNA-binding domain
PMLHKFCF_00264 1.8e-181 oppF P Belongs to the ABC transporter superfamily
PMLHKFCF_00265 9.2e-203 oppD P Belongs to the ABC transporter superfamily
PMLHKFCF_00266 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMLHKFCF_00267 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMLHKFCF_00268 1.3e-309 oppA E ABC transporter, substratebinding protein
PMLHKFCF_00269 3.2e-57 ywjH S Protein of unknown function (DUF1634)
PMLHKFCF_00270 5.5e-126 yxaA S membrane transporter protein
PMLHKFCF_00271 7.1e-161 lysR5 K LysR substrate binding domain
PMLHKFCF_00272 2.7e-196 M MucBP domain
PMLHKFCF_00273 1.7e-273
PMLHKFCF_00274 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PMLHKFCF_00275 2.4e-253 gor 1.8.1.7 C Glutathione reductase
PMLHKFCF_00276 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
PMLHKFCF_00277 3e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
PMLHKFCF_00278 9.5e-213 gntP EG Gluconate
PMLHKFCF_00279 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
PMLHKFCF_00280 9.3e-188 yueF S AI-2E family transporter
PMLHKFCF_00281 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PMLHKFCF_00282 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
PMLHKFCF_00283 7.8e-48 K sequence-specific DNA binding
PMLHKFCF_00284 2.5e-133 cwlO M NlpC/P60 family
PMLHKFCF_00285 4.1e-106 ygaC J Belongs to the UPF0374 family
PMLHKFCF_00286 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
PMLHKFCF_00287 3e-125
PMLHKFCF_00288 6.8e-101 K DNA-templated transcription, initiation
PMLHKFCF_00289 1.3e-25
PMLHKFCF_00290 7e-30
PMLHKFCF_00291 7.3e-33 S Protein of unknown function (DUF2922)
PMLHKFCF_00292 3.8e-53
PMLHKFCF_00293 2.2e-17 L Helix-turn-helix domain
PMLHKFCF_00294 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PMLHKFCF_00295 1.4e-154 yihY S Belongs to the UPF0761 family
PMLHKFCF_00296 1.5e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PMLHKFCF_00297 1.2e-219 pbpX1 V Beta-lactamase
PMLHKFCF_00298 8.4e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PMLHKFCF_00299 1.4e-106
PMLHKFCF_00300 1.3e-73
PMLHKFCF_00302 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_00303 2.9e-243 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLHKFCF_00304 2.3e-75 T Universal stress protein family
PMLHKFCF_00306 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
PMLHKFCF_00307 2.4e-189 mocA S Oxidoreductase
PMLHKFCF_00308 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
PMLHKFCF_00309 1.1e-62 S Domain of unknown function (DUF4828)
PMLHKFCF_00310 2e-143 lys M Glycosyl hydrolases family 25
PMLHKFCF_00311 2.3e-151 gntR K rpiR family
PMLHKFCF_00312 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_00313 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLHKFCF_00314 0.0 yfgQ P E1-E2 ATPase
PMLHKFCF_00315 6e-100 yobS K Bacterial regulatory proteins, tetR family
PMLHKFCF_00316 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PMLHKFCF_00317 1e-190 yegS 2.7.1.107 G Lipid kinase
PMLHKFCF_00318 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PMLHKFCF_00319 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PMLHKFCF_00320 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PMLHKFCF_00321 2.6e-198 camS S sex pheromone
PMLHKFCF_00322 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PMLHKFCF_00323 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PMLHKFCF_00324 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PMLHKFCF_00325 1e-93 S UPF0316 protein
PMLHKFCF_00326 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PMLHKFCF_00327 3.4e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
PMLHKFCF_00328 7.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
PMLHKFCF_00329 2.7e-31 L Transposase
PMLHKFCF_00333 1.7e-63 K Helix-turn-helix XRE-family like proteins
PMLHKFCF_00334 6.2e-50
PMLHKFCF_00335 4.3e-78
PMLHKFCF_00336 8.9e-23 L hmm pf00665
PMLHKFCF_00337 6.9e-29 L hmm pf00665
PMLHKFCF_00338 7.6e-46 L Helix-turn-helix domain
PMLHKFCF_00340 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
PMLHKFCF_00342 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PMLHKFCF_00343 1.2e-179 coaA 2.7.1.33 F Pantothenic acid kinase
PMLHKFCF_00344 2.5e-164 fabK 1.3.1.9 S Nitronate monooxygenase
PMLHKFCF_00345 0.0 helD 3.6.4.12 L DNA helicase
PMLHKFCF_00346 7.2e-110 dedA S SNARE associated Golgi protein
PMLHKFCF_00347 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
PMLHKFCF_00348 0.0 yjbQ P TrkA C-terminal domain protein
PMLHKFCF_00349 4.7e-125 pgm3 G Phosphoglycerate mutase family
PMLHKFCF_00350 5.5e-129 pgm3 G Phosphoglycerate mutase family
PMLHKFCF_00351 1.2e-26
PMLHKFCF_00352 1.3e-48 sugE U Multidrug resistance protein
PMLHKFCF_00353 2.9e-78 3.6.1.55 F NUDIX domain
PMLHKFCF_00354 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PMLHKFCF_00355 7.1e-98 K Bacterial regulatory proteins, tetR family
PMLHKFCF_00356 3.8e-85 S membrane transporter protein
PMLHKFCF_00357 4.9e-210 EGP Major facilitator Superfamily
PMLHKFCF_00358 2.8e-70 K MarR family
PMLHKFCF_00359 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
PMLHKFCF_00360 7.4e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
PMLHKFCF_00361 1.4e-245 steT E amino acid
PMLHKFCF_00362 6.1e-140 G YdjC-like protein
PMLHKFCF_00363 4.4e-256 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
PMLHKFCF_00364 1.4e-153 K CAT RNA binding domain
PMLHKFCF_00365 4.4e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PMLHKFCF_00366 4e-108 glnP P ABC transporter permease
PMLHKFCF_00367 1.6e-109 gluC P ABC transporter permease
PMLHKFCF_00368 7.8e-149 glnH ET ABC transporter substrate-binding protein
PMLHKFCF_00369 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMLHKFCF_00371 3.6e-41
PMLHKFCF_00372 9.5e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMLHKFCF_00373 3.2e-184 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PMLHKFCF_00374 1.7e-73 gph 3.1.3.18 S HAD hydrolase, family IA, variant
PMLHKFCF_00375 4.9e-148
PMLHKFCF_00376 7.1e-12 3.2.1.14 GH18
PMLHKFCF_00377 1.3e-81 zur P Belongs to the Fur family
PMLHKFCF_00378 1.2e-103 gmk2 2.7.4.8 F Guanylate kinase
PMLHKFCF_00379 1.8e-19
PMLHKFCF_00380 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
PMLHKFCF_00381 1.6e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PMLHKFCF_00382 2.5e-88
PMLHKFCF_00383 1.1e-251 yfnA E Amino Acid
PMLHKFCF_00384 2.6e-46
PMLHKFCF_00385 1.1e-68 O OsmC-like protein
PMLHKFCF_00386 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PMLHKFCF_00387 0.0 oatA I Acyltransferase
PMLHKFCF_00388 5.9e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PMLHKFCF_00389 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
PMLHKFCF_00390 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PMLHKFCF_00391 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PMLHKFCF_00392 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PMLHKFCF_00393 1.2e-225 pbuG S permease
PMLHKFCF_00394 1.5e-19
PMLHKFCF_00395 1.2e-82 K Transcriptional regulator
PMLHKFCF_00396 2.5e-152 licD M LicD family
PMLHKFCF_00397 4.1e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PMLHKFCF_00398 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PMLHKFCF_00399 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PMLHKFCF_00400 3.6e-242 EGP Major facilitator Superfamily
PMLHKFCF_00401 2.5e-89 V VanZ like family
PMLHKFCF_00402 1.5e-33
PMLHKFCF_00403 1.9e-71 spxA 1.20.4.1 P ArsC family
PMLHKFCF_00405 2.1e-143
PMLHKFCF_00406 3.1e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PMLHKFCF_00407 8.8e-154 G Transmembrane secretion effector
PMLHKFCF_00408 3e-131 1.5.1.39 C nitroreductase
PMLHKFCF_00409 3e-72
PMLHKFCF_00410 1.5e-52
PMLHKFCF_00411 1.2e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PMLHKFCF_00412 3.1e-104 K Bacterial regulatory proteins, tetR family
PMLHKFCF_00413 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
PMLHKFCF_00414 4.5e-123 yliE T EAL domain
PMLHKFCF_00415 0.0 yfbS P Sodium:sulfate symporter transmembrane region
PMLHKFCF_00416 2.1e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
PMLHKFCF_00417 8.5e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
PMLHKFCF_00418 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
PMLHKFCF_00419 1.6e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
PMLHKFCF_00420 1.2e-307 S Protein conserved in bacteria
PMLHKFCF_00421 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PMLHKFCF_00422 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PMLHKFCF_00423 3.6e-58 S Protein of unknown function (DUF1516)
PMLHKFCF_00424 1.9e-89 gtcA S Teichoic acid glycosylation protein
PMLHKFCF_00425 2.1e-180
PMLHKFCF_00426 3.5e-10
PMLHKFCF_00427 5.9e-52
PMLHKFCF_00430 0.0 uvrA2 L ABC transporter
PMLHKFCF_00431 2.5e-46
PMLHKFCF_00432 1e-90
PMLHKFCF_00433 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
PMLHKFCF_00434 1.9e-113 S CAAX protease self-immunity
PMLHKFCF_00435 2.5e-59
PMLHKFCF_00436 4.5e-55
PMLHKFCF_00437 1.6e-137 pltR K LytTr DNA-binding domain
PMLHKFCF_00438 2.5e-223 pltK 2.7.13.3 T GHKL domain
PMLHKFCF_00439 1.7e-108
PMLHKFCF_00440 3.2e-147 S Sucrose-6F-phosphate phosphohydrolase
PMLHKFCF_00441 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PMLHKFCF_00442 3.5e-117 GM NAD(P)H-binding
PMLHKFCF_00443 1.6e-64 K helix_turn_helix, mercury resistance
PMLHKFCF_00444 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMLHKFCF_00446 4e-176 K LytTr DNA-binding domain
PMLHKFCF_00447 2.3e-156 V ABC transporter
PMLHKFCF_00448 2.6e-124 V Transport permease protein
PMLHKFCF_00450 3.9e-179 XK27_06930 V domain protein
PMLHKFCF_00451 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PMLHKFCF_00452 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
PMLHKFCF_00453 2.5e-180 ugpB G Bacterial extracellular solute-binding protein
PMLHKFCF_00454 1.1e-150 ugpE G ABC transporter permease
PMLHKFCF_00455 5.2e-173 ugpA U Binding-protein-dependent transport system inner membrane component
PMLHKFCF_00456 5.2e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
PMLHKFCF_00457 4.1e-84 uspA T Belongs to the universal stress protein A family
PMLHKFCF_00458 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
PMLHKFCF_00459 1.9e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PMLHKFCF_00460 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PMLHKFCF_00461 3e-301 ytgP S Polysaccharide biosynthesis protein
PMLHKFCF_00462 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMLHKFCF_00463 1.4e-124 3.6.1.27 I Acid phosphatase homologues
PMLHKFCF_00464 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
PMLHKFCF_00465 4.2e-29
PMLHKFCF_00466 2.2e-298 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
PMLHKFCF_00467 3.3e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
PMLHKFCF_00468 0.0 S Pfam Methyltransferase
PMLHKFCF_00469 2.1e-139 N Cell shape-determining protein MreB
PMLHKFCF_00470 1.7e-18 N Cell shape-determining protein MreB
PMLHKFCF_00471 5.5e-278 bmr3 EGP Major facilitator Superfamily
PMLHKFCF_00472 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PMLHKFCF_00473 1.6e-121
PMLHKFCF_00474 1.5e-291 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
PMLHKFCF_00475 7.5e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PMLHKFCF_00476 9.2e-256 mmuP E amino acid
PMLHKFCF_00477 4e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PMLHKFCF_00478 3.7e-230 mntH P H( )-stimulated, divalent metal cation uptake system
PMLHKFCF_00480 3.3e-104 T Calcineurin-like phosphoesterase superfamily domain
PMLHKFCF_00481 8.6e-37 T Calcineurin-like phosphoesterase superfamily domain
PMLHKFCF_00482 2e-94 K Acetyltransferase (GNAT) domain
PMLHKFCF_00483 1.4e-95
PMLHKFCF_00484 8.9e-182 P secondary active sulfate transmembrane transporter activity
PMLHKFCF_00485 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
PMLHKFCF_00491 5.1e-08
PMLHKFCF_00497 1.7e-52 M Lysin motif
PMLHKFCF_00498 4.5e-121 S CAAX protease self-immunity
PMLHKFCF_00499 2.5e-114 V CAAX protease self-immunity
PMLHKFCF_00500 7.1e-121 yclH V ABC transporter
PMLHKFCF_00501 1.8e-185 yclI V MacB-like periplasmic core domain
PMLHKFCF_00502 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
PMLHKFCF_00503 1.1e-106 tag 3.2.2.20 L glycosylase
PMLHKFCF_00504 0.0 ydgH S MMPL family
PMLHKFCF_00505 3.1e-104 K transcriptional regulator
PMLHKFCF_00506 2.7e-123 2.7.6.5 S RelA SpoT domain protein
PMLHKFCF_00507 1.3e-47
PMLHKFCF_00508 1.1e-256 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
PMLHKFCF_00509 3.2e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PMLHKFCF_00510 2.1e-41
PMLHKFCF_00511 3.2e-55
PMLHKFCF_00512 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLHKFCF_00513 2.7e-129 yidA K Helix-turn-helix domain, rpiR family
PMLHKFCF_00514 4.1e-49
PMLHKFCF_00515 7e-127 K Transcriptional regulatory protein, C terminal
PMLHKFCF_00516 9.8e-250 T PhoQ Sensor
PMLHKFCF_00517 3.3e-65 K helix_turn_helix, mercury resistance
PMLHKFCF_00518 1.1e-251 ydiC1 EGP Major facilitator Superfamily
PMLHKFCF_00519 1.4e-40
PMLHKFCF_00520 5.9e-38
PMLHKFCF_00521 5.1e-116
PMLHKFCF_00522 6.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
PMLHKFCF_00523 3.7e-120 K Bacterial regulatory proteins, tetR family
PMLHKFCF_00524 1.8e-72 K Transcriptional regulator
PMLHKFCF_00525 3.5e-70
PMLHKFCF_00526 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PMLHKFCF_00527 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PMLHKFCF_00528 5.8e-238 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
PMLHKFCF_00529 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
PMLHKFCF_00530 1.4e-144
PMLHKFCF_00531 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
PMLHKFCF_00532 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PMLHKFCF_00533 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
PMLHKFCF_00534 3.5e-129 treR K UTRA
PMLHKFCF_00535 2.9e-42
PMLHKFCF_00536 7.3e-43 S Protein of unknown function (DUF2089)
PMLHKFCF_00537 4.3e-141 pnuC H nicotinamide mononucleotide transporter
PMLHKFCF_00538 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
PMLHKFCF_00539 2.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PMLHKFCF_00540 1.4e-209 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PMLHKFCF_00541 1.2e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
PMLHKFCF_00542 3.5e-97 yieF S NADPH-dependent FMN reductase
PMLHKFCF_00543 8.4e-254 S Uncharacterized protein conserved in bacteria (DUF2252)
PMLHKFCF_00544 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
PMLHKFCF_00545 7.7e-62
PMLHKFCF_00546 6.2e-94
PMLHKFCF_00547 1.2e-49
PMLHKFCF_00548 6.2e-57 trxA1 O Belongs to the thioredoxin family
PMLHKFCF_00549 2.1e-73
PMLHKFCF_00550 8.1e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
PMLHKFCF_00551 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLHKFCF_00552 0.0 mtlR K Mga helix-turn-helix domain
PMLHKFCF_00553 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
PMLHKFCF_00554 7.4e-277 pipD E Dipeptidase
PMLHKFCF_00555 4.8e-99 K Helix-turn-helix domain
PMLHKFCF_00556 5.9e-224 1.3.5.4 C FAD dependent oxidoreductase
PMLHKFCF_00557 2.2e-173 P Major Facilitator Superfamily
PMLHKFCF_00558 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PMLHKFCF_00559 4.7e-31 ygzD K Transcriptional
PMLHKFCF_00560 1e-69
PMLHKFCF_00561 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PMLHKFCF_00562 1.4e-158 dkgB S reductase
PMLHKFCF_00563 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PMLHKFCF_00564 3.1e-101 S ABC transporter permease
PMLHKFCF_00565 2e-258 P ABC transporter
PMLHKFCF_00566 3.1e-116 P cobalt transport
PMLHKFCF_00567 5.6e-19 S ATPases associated with a variety of cellular activities
PMLHKFCF_00568 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PMLHKFCF_00569 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMLHKFCF_00570 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PMLHKFCF_00571 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PMLHKFCF_00572 5e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PMLHKFCF_00573 6.4e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PMLHKFCF_00574 3.1e-74 yabR J RNA binding
PMLHKFCF_00575 1.1e-63 divIC D Septum formation initiator
PMLHKFCF_00577 2.2e-42 yabO J S4 domain protein
PMLHKFCF_00578 4.3e-289 yabM S Polysaccharide biosynthesis protein
PMLHKFCF_00579 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PMLHKFCF_00580 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PMLHKFCF_00581 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PMLHKFCF_00582 4.2e-264 S Putative peptidoglycan binding domain
PMLHKFCF_00583 6.2e-114 S (CBS) domain
PMLHKFCF_00584 4.1e-84 S QueT transporter
PMLHKFCF_00585 3.6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PMLHKFCF_00586 5.1e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
PMLHKFCF_00587 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
PMLHKFCF_00588 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PMLHKFCF_00589 7.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PMLHKFCF_00590 8.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PMLHKFCF_00591 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PMLHKFCF_00592 1.9e-133 P ATPases associated with a variety of cellular activities
PMLHKFCF_00593 2.2e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
PMLHKFCF_00594 2.9e-193 P ABC transporter, substratebinding protein
PMLHKFCF_00595 0.0 kup P Transport of potassium into the cell
PMLHKFCF_00596 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
PMLHKFCF_00597 9.3e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PMLHKFCF_00598 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PMLHKFCF_00599 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PMLHKFCF_00600 3.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PMLHKFCF_00601 2e-146
PMLHKFCF_00602 4.6e-139 htpX O Belongs to the peptidase M48B family
PMLHKFCF_00603 1.7e-91 lemA S LemA family
PMLHKFCF_00604 9.2e-127 srtA 3.4.22.70 M sortase family
PMLHKFCF_00605 3.2e-214 J translation release factor activity
PMLHKFCF_00606 7.8e-41 rpmE2 J Ribosomal protein L31
PMLHKFCF_00607 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PMLHKFCF_00608 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PMLHKFCF_00609 2.5e-26
PMLHKFCF_00610 6.4e-131 S YheO-like PAS domain
PMLHKFCF_00611 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PMLHKFCF_00612 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PMLHKFCF_00613 3.1e-229 tdcC E amino acid
PMLHKFCF_00614 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PMLHKFCF_00615 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PMLHKFCF_00616 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PMLHKFCF_00617 3.8e-78 ywiB S Domain of unknown function (DUF1934)
PMLHKFCF_00618 4.7e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
PMLHKFCF_00619 9e-264 ywfO S HD domain protein
PMLHKFCF_00620 2.9e-148 yxeH S hydrolase
PMLHKFCF_00621 1.7e-101 S WxL domain surface cell wall-binding
PMLHKFCF_00622 3.6e-183 S Cell surface protein
PMLHKFCF_00623 8.4e-75
PMLHKFCF_00624 8.4e-263
PMLHKFCF_00625 2.3e-227 hpk9 2.7.13.3 T GHKL domain
PMLHKFCF_00626 2.9e-38 S TfoX C-terminal domain
PMLHKFCF_00627 6e-140 K Helix-turn-helix domain
PMLHKFCF_00628 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PMLHKFCF_00629 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PMLHKFCF_00630 3.2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PMLHKFCF_00631 0.0 ctpA 3.6.3.54 P P-type ATPase
PMLHKFCF_00632 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PMLHKFCF_00633 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
PMLHKFCF_00634 1.1e-65 lysM M LysM domain
PMLHKFCF_00635 9.6e-267 yjeM E Amino Acid
PMLHKFCF_00636 4.3e-144 K Helix-turn-helix XRE-family like proteins
PMLHKFCF_00637 7.4e-71
PMLHKFCF_00639 7.7e-163 IQ KR domain
PMLHKFCF_00640 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
PMLHKFCF_00642 6.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
PMLHKFCF_00643 0.0 V ABC transporter
PMLHKFCF_00644 8.6e-218 ykiI
PMLHKFCF_00645 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
PMLHKFCF_00646 1.2e-73 S Psort location Cytoplasmic, score
PMLHKFCF_00647 3.3e-219 T diguanylate cyclase
PMLHKFCF_00648 2e-120 tag 3.2.2.20 L Methyladenine glycosylase
PMLHKFCF_00649 4.2e-92
PMLHKFCF_00650 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
PMLHKFCF_00651 1.8e-54 nudA S ASCH
PMLHKFCF_00652 1.8e-107 S SdpI/YhfL protein family
PMLHKFCF_00653 6.7e-87 M Lysin motif
PMLHKFCF_00654 2.3e-65 M LysM domain
PMLHKFCF_00655 5.1e-75 K helix_turn_helix, mercury resistance
PMLHKFCF_00656 5.3e-184 1.1.1.219 GM Male sterility protein
PMLHKFCF_00657 9.2e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLHKFCF_00658 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLHKFCF_00659 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PMLHKFCF_00660 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PMLHKFCF_00661 5.3e-150 dicA K Helix-turn-helix domain
PMLHKFCF_00662 3.2e-55
PMLHKFCF_00663 1.3e-159 T Calcineurin-like phosphoesterase superfamily domain
PMLHKFCF_00664 7.4e-64
PMLHKFCF_00665 0.0 P Concanavalin A-like lectin/glucanases superfamily
PMLHKFCF_00666 0.0 yhcA V ABC transporter, ATP-binding protein
PMLHKFCF_00667 1.2e-95 cadD P Cadmium resistance transporter
PMLHKFCF_00668 2e-49 K Transcriptional regulator, ArsR family
PMLHKFCF_00669 1.9e-116 S SNARE associated Golgi protein
PMLHKFCF_00670 1.1e-46
PMLHKFCF_00671 6.8e-72 T Belongs to the universal stress protein A family
PMLHKFCF_00672 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
PMLHKFCF_00673 6.1e-122 K Helix-turn-helix XRE-family like proteins
PMLHKFCF_00674 2.8e-82 gtrA S GtrA-like protein
PMLHKFCF_00675 6.6e-113 zmp3 O Zinc-dependent metalloprotease
PMLHKFCF_00676 1.8e-84 hmpT S Pfam:DUF3816
PMLHKFCF_00677 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PMLHKFCF_00678 3.9e-111
PMLHKFCF_00679 2.4e-149 M Glycosyl hydrolases family 25
PMLHKFCF_00680 2e-143 yvpB S Peptidase_C39 like family
PMLHKFCF_00681 1.1e-92 yueI S Protein of unknown function (DUF1694)
PMLHKFCF_00682 1.6e-115 S Protein of unknown function (DUF554)
PMLHKFCF_00683 6.4e-148 KT helix_turn_helix, mercury resistance
PMLHKFCF_00684 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PMLHKFCF_00685 6.6e-95 S Protein of unknown function (DUF1440)
PMLHKFCF_00686 5.2e-174 hrtB V ABC transporter permease
PMLHKFCF_00687 2.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PMLHKFCF_00688 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
PMLHKFCF_00689 4.2e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PMLHKFCF_00690 8.1e-99 1.5.1.3 H RibD C-terminal domain
PMLHKFCF_00691 1.1e-185 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PMLHKFCF_00692 6.4e-117 S Membrane
PMLHKFCF_00693 1.2e-155 mleP3 S Membrane transport protein
PMLHKFCF_00694 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
PMLHKFCF_00695 1.3e-189 ynfM EGP Major facilitator Superfamily
PMLHKFCF_00696 2.8e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PMLHKFCF_00697 4.1e-270 lmrB EGP Major facilitator Superfamily
PMLHKFCF_00698 2e-75 S Domain of unknown function (DUF4811)
PMLHKFCF_00699 1.8e-101 rimL J Acetyltransferase (GNAT) domain
PMLHKFCF_00700 9.3e-173 S Conserved hypothetical protein 698
PMLHKFCF_00701 4.8e-151 rlrG K Transcriptional regulator
PMLHKFCF_00702 7.6e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
PMLHKFCF_00703 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
PMLHKFCF_00705 1.8e-46 lytE M LysM domain
PMLHKFCF_00706 1.2e-91 ogt 2.1.1.63 L Methyltransferase
PMLHKFCF_00707 7.5e-166 natA S ABC transporter, ATP-binding protein
PMLHKFCF_00708 1.4e-210 natB CP ABC-2 family transporter protein
PMLHKFCF_00709 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PMLHKFCF_00710 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
PMLHKFCF_00711 3.2e-76 yphH S Cupin domain
PMLHKFCF_00712 2.9e-78 K transcriptional regulator, MerR family
PMLHKFCF_00713 1.4e-234 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PMLHKFCF_00714 0.0 ylbB V ABC transporter permease
PMLHKFCF_00715 7.5e-121 macB V ABC transporter, ATP-binding protein
PMLHKFCF_00717 2.3e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PMLHKFCF_00718 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PMLHKFCF_00719 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PMLHKFCF_00721 3.8e-84
PMLHKFCF_00722 2.8e-85 yvbK 3.1.3.25 K GNAT family
PMLHKFCF_00723 3.2e-37
PMLHKFCF_00724 8.2e-48
PMLHKFCF_00725 1.4e-110 pgm8 G Histidine phosphatase superfamily (branch 1)
PMLHKFCF_00726 3.8e-63 S Domain of unknown function (DUF4440)
PMLHKFCF_00727 6.9e-156 K LysR substrate binding domain
PMLHKFCF_00728 1.9e-104 GM NAD(P)H-binding
PMLHKFCF_00729 1.5e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PMLHKFCF_00730 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
PMLHKFCF_00731 1.3e-34
PMLHKFCF_00732 6.1e-76 T Belongs to the universal stress protein A family
PMLHKFCF_00733 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
PMLHKFCF_00734 4.4e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PMLHKFCF_00735 2.1e-31
PMLHKFCF_00736 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
PMLHKFCF_00737 0.0 cadA P P-type ATPase
PMLHKFCF_00739 1.8e-124 yyaQ S YjbR
PMLHKFCF_00740 2.9e-29 S Uncharacterized protein conserved in bacteria (DUF2325)
PMLHKFCF_00741 2.8e-168 S Uncharacterized protein conserved in bacteria (DUF2325)
PMLHKFCF_00742 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PMLHKFCF_00743 2.2e-199 frlB M SIS domain
PMLHKFCF_00744 3e-26 3.2.2.10 S Belongs to the LOG family
PMLHKFCF_00745 3.4e-253 nhaC C Na H antiporter NhaC
PMLHKFCF_00746 1.3e-249 cycA E Amino acid permease
PMLHKFCF_00747 5.7e-73 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_00748 3.6e-71 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_00749 1.6e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
PMLHKFCF_00750 7.7e-160 azoB GM NmrA-like family
PMLHKFCF_00751 5.4e-66 K Winged helix DNA-binding domain
PMLHKFCF_00752 7e-71 spx4 1.20.4.1 P ArsC family
PMLHKFCF_00753 1.7e-66 yeaO S Protein of unknown function, DUF488
PMLHKFCF_00754 4e-53
PMLHKFCF_00755 4.1e-214 mutY L A G-specific adenine glycosylase
PMLHKFCF_00756 1.9e-62
PMLHKFCF_00757 4.3e-86
PMLHKFCF_00758 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
PMLHKFCF_00759 5.9e-55
PMLHKFCF_00760 2.1e-14
PMLHKFCF_00761 1.1e-115 GM NmrA-like family
PMLHKFCF_00762 1.3e-81 elaA S GNAT family
PMLHKFCF_00763 5.9e-158 EG EamA-like transporter family
PMLHKFCF_00764 1.8e-119 S membrane
PMLHKFCF_00765 6.8e-111 S VIT family
PMLHKFCF_00766 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PMLHKFCF_00767 0.0 copB 3.6.3.4 P P-type ATPase
PMLHKFCF_00768 4.7e-73 copR K Copper transport repressor CopY TcrY
PMLHKFCF_00769 7.4e-40
PMLHKFCF_00770 7.7e-73 S COG NOG18757 non supervised orthologous group
PMLHKFCF_00771 1.5e-248 lmrB EGP Major facilitator Superfamily
PMLHKFCF_00772 3.4e-25
PMLHKFCF_00773 4.2e-49
PMLHKFCF_00774 1.6e-64 ycgX S Protein of unknown function (DUF1398)
PMLHKFCF_00775 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
PMLHKFCF_00776 5.9e-214 mdtG EGP Major facilitator Superfamily
PMLHKFCF_00777 2.6e-180 D Alpha beta
PMLHKFCF_00778 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
PMLHKFCF_00779 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PMLHKFCF_00780 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
PMLHKFCF_00781 6.4e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PMLHKFCF_00782 8.4e-152 ywkB S Membrane transport protein
PMLHKFCF_00783 5.2e-164 yvgN C Aldo keto reductase
PMLHKFCF_00784 9.2e-133 thrE S Putative threonine/serine exporter
PMLHKFCF_00785 7.5e-77 S Threonine/Serine exporter, ThrE
PMLHKFCF_00786 2.3e-43 S Protein of unknown function (DUF1093)
PMLHKFCF_00787 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PMLHKFCF_00788 2.7e-91 ymdB S Macro domain protein
PMLHKFCF_00789 1.2e-95 K transcriptional regulator
PMLHKFCF_00790 5.5e-50 yvlA
PMLHKFCF_00791 6e-161 ypuA S Protein of unknown function (DUF1002)
PMLHKFCF_00792 0.0
PMLHKFCF_00793 1.7e-121 S Bacterial protein of unknown function (DUF916)
PMLHKFCF_00794 8.2e-207 ica2 GT2 M Glycosyl transferase family group 2
PMLHKFCF_00795 1.2e-286
PMLHKFCF_00796 8.2e-205 ftsW D Belongs to the SEDS family
PMLHKFCF_00797 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PMLHKFCF_00798 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PMLHKFCF_00799 2.2e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PMLHKFCF_00800 1.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PMLHKFCF_00801 9.6e-197 ylbL T Belongs to the peptidase S16 family
PMLHKFCF_00802 6.2e-64 comEA L Competence protein ComEA
PMLHKFCF_00803 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
PMLHKFCF_00804 0.0 comEC S Competence protein ComEC
PMLHKFCF_00805 7e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
PMLHKFCF_00806 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
PMLHKFCF_00807 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PMLHKFCF_00808 7.2e-103 mdtG EGP Major Facilitator Superfamily
PMLHKFCF_00809 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMLHKFCF_00810 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PMLHKFCF_00811 1e-157 S Tetratricopeptide repeat
PMLHKFCF_00812 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PMLHKFCF_00813 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PMLHKFCF_00814 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PMLHKFCF_00815 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PMLHKFCF_00816 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PMLHKFCF_00817 9.9e-73 S Iron-sulphur cluster biosynthesis
PMLHKFCF_00818 4.3e-22
PMLHKFCF_00819 9.2e-270 glnPH2 P ABC transporter permease
PMLHKFCF_00820 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMLHKFCF_00821 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PMLHKFCF_00822 2.9e-126 epsB M biosynthesis protein
PMLHKFCF_00823 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PMLHKFCF_00824 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
PMLHKFCF_00825 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
PMLHKFCF_00826 7.4e-126 tuaA M Bacterial sugar transferase
PMLHKFCF_00827 5.6e-175 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
PMLHKFCF_00828 2.7e-103 cps4G M Glycosyltransferase Family 4
PMLHKFCF_00829 6.5e-38 cps4G M Glycosyltransferase Family 4
PMLHKFCF_00830 1.3e-232
PMLHKFCF_00831 3e-176 cps4I M Glycosyltransferase like family 2
PMLHKFCF_00832 4.5e-261 cps4J S Polysaccharide biosynthesis protein
PMLHKFCF_00833 3.8e-251 cpdA S Calcineurin-like phosphoesterase
PMLHKFCF_00834 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
PMLHKFCF_00835 2.3e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PMLHKFCF_00836 1.5e-135 fruR K DeoR C terminal sensor domain
PMLHKFCF_00837 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PMLHKFCF_00838 3.2e-46
PMLHKFCF_00839 8.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PMLHKFCF_00840 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PMLHKFCF_00841 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
PMLHKFCF_00842 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PMLHKFCF_00843 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PMLHKFCF_00844 1.5e-98 K Helix-turn-helix domain
PMLHKFCF_00845 6.1e-211 EGP Major facilitator Superfamily
PMLHKFCF_00846 8.5e-57 ybjQ S Belongs to the UPF0145 family
PMLHKFCF_00847 1.1e-138 Q Methyltransferase
PMLHKFCF_00848 3.6e-31
PMLHKFCF_00849 4.6e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PMLHKFCF_00850 3.4e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PMLHKFCF_00851 2.9e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PMLHKFCF_00852 1.6e-180 galR K Transcriptional regulator
PMLHKFCF_00853 8e-76 K Helix-turn-helix XRE-family like proteins
PMLHKFCF_00854 2.4e-22 fic D Fic/DOC family
PMLHKFCF_00855 1.9e-25 fic D Fic/DOC family
PMLHKFCF_00856 2.1e-38 fic D Fic/DOC family
PMLHKFCF_00857 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
PMLHKFCF_00858 2.5e-231 EGP Major facilitator Superfamily
PMLHKFCF_00859 2.1e-304 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PMLHKFCF_00860 2.3e-229 mdtH P Sugar (and other) transporter
PMLHKFCF_00861 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PMLHKFCF_00862 1.4e-248 brnQ U Component of the transport system for branched-chain amino acids
PMLHKFCF_00863 0.0 ubiB S ABC1 family
PMLHKFCF_00864 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
PMLHKFCF_00865 3.9e-218 3.1.3.1 S associated with various cellular activities
PMLHKFCF_00866 1.4e-248 S Putative metallopeptidase domain
PMLHKFCF_00867 1.5e-49
PMLHKFCF_00868 7.7e-103 K Bacterial regulatory proteins, tetR family
PMLHKFCF_00869 4.6e-45
PMLHKFCF_00870 2.3e-99 S WxL domain surface cell wall-binding
PMLHKFCF_00871 1.5e-118 S WxL domain surface cell wall-binding
PMLHKFCF_00872 6.1e-164 S Cell surface protein
PMLHKFCF_00873 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
PMLHKFCF_00874 1.3e-262 nox C NADH oxidase
PMLHKFCF_00875 3.2e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PMLHKFCF_00876 0.0 pepO 3.4.24.71 O Peptidase family M13
PMLHKFCF_00877 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
PMLHKFCF_00878 1.6e-32 copZ P Heavy-metal-associated domain
PMLHKFCF_00879 6.6e-96 dps P Belongs to the Dps family
PMLHKFCF_00880 1.2e-18
PMLHKFCF_00881 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
PMLHKFCF_00882 1.5e-55 txlA O Thioredoxin-like domain
PMLHKFCF_00883 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PMLHKFCF_00884 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PMLHKFCF_00885 1.1e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
PMLHKFCF_00886 6.3e-128 ydcF S Gram-negative-bacterium-type cell wall biogenesis
PMLHKFCF_00887 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PMLHKFCF_00888 1.4e-181 yfeX P Peroxidase
PMLHKFCF_00889 1.3e-102 K transcriptional regulator
PMLHKFCF_00890 1.7e-07 4.1.1.46 S metal-dependent hydrolase of the TIM-barrel fold
PMLHKFCF_00891 2.6e-65
PMLHKFCF_00893 1.6e-61
PMLHKFCF_00894 2.5e-53
PMLHKFCF_00895 2e-72 mltD CBM50 M PFAM NLP P60 protein
PMLHKFCF_00896 4.6e-279 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PMLHKFCF_00897 1.8e-27
PMLHKFCF_00898 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
PMLHKFCF_00899 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
PMLHKFCF_00900 1.3e-87 K Winged helix DNA-binding domain
PMLHKFCF_00901 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
PMLHKFCF_00902 5.1e-129 S WxL domain surface cell wall-binding
PMLHKFCF_00903 2e-56 S Bacterial protein of unknown function (DUF916)
PMLHKFCF_00904 7.8e-296 S ABC transporter, ATP-binding protein
PMLHKFCF_00905 2e-106 3.2.2.20 K acetyltransferase
PMLHKFCF_00906 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PMLHKFCF_00907 6e-39
PMLHKFCF_00908 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
PMLHKFCF_00909 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PMLHKFCF_00910 5e-162 degV S Uncharacterised protein, DegV family COG1307
PMLHKFCF_00911 4e-229 hom1 1.1.1.3 E Homoserine dehydrogenase
PMLHKFCF_00912 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PMLHKFCF_00913 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PMLHKFCF_00914 3.1e-176 XK27_08835 S ABC transporter
PMLHKFCF_00915 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PMLHKFCF_00916 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
PMLHKFCF_00917 5.7e-258 npr 1.11.1.1 C NADH oxidase
PMLHKFCF_00918 4.2e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
PMLHKFCF_00919 3.1e-136 terC P membrane
PMLHKFCF_00920 3.1e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PMLHKFCF_00921 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PMLHKFCF_00922 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PMLHKFCF_00923 3.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PMLHKFCF_00924 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PMLHKFCF_00925 2.2e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PMLHKFCF_00926 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PMLHKFCF_00927 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PMLHKFCF_00928 4.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PMLHKFCF_00929 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PMLHKFCF_00930 1.9e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PMLHKFCF_00931 3.8e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
PMLHKFCF_00932 4.6e-216 ysaA V RDD family
PMLHKFCF_00933 7.6e-166 corA P CorA-like Mg2+ transporter protein
PMLHKFCF_00934 2.1e-55 S Domain of unknown function (DU1801)
PMLHKFCF_00935 5.9e-91 rmeB K transcriptional regulator, MerR family
PMLHKFCF_00936 1.4e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
PMLHKFCF_00937 8.6e-98 J glyoxalase III activity
PMLHKFCF_00938 5.2e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PMLHKFCF_00939 5.9e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PMLHKFCF_00940 3.7e-34
PMLHKFCF_00941 2.6e-112 S Protein of unknown function (DUF1211)
PMLHKFCF_00942 0.0 ydgH S MMPL family
PMLHKFCF_00943 1.5e-41 M domain protein
PMLHKFCF_00944 3.9e-219 M domain protein
PMLHKFCF_00945 1.5e-74 yjcF S Acetyltransferase (GNAT) domain
PMLHKFCF_00946 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PMLHKFCF_00947 0.0 glpQ 3.1.4.46 C phosphodiesterase
PMLHKFCF_00948 3.4e-183 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PMLHKFCF_00949 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_00950 5.9e-182 3.6.4.13 S domain, Protein
PMLHKFCF_00951 3.6e-168 S Polyphosphate kinase 2 (PPK2)
PMLHKFCF_00952 1.2e-97 drgA C Nitroreductase family
PMLHKFCF_00953 7e-178 iunH2 3.2.2.1 F nucleoside hydrolase
PMLHKFCF_00954 2.2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PMLHKFCF_00955 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
PMLHKFCF_00956 2.3e-157 ccpB 5.1.1.1 K lacI family
PMLHKFCF_00957 1.1e-116 K Helix-turn-helix domain, rpiR family
PMLHKFCF_00958 6e-177 S Oxidoreductase family, NAD-binding Rossmann fold
PMLHKFCF_00959 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
PMLHKFCF_00960 0.0 yjcE P Sodium proton antiporter
PMLHKFCF_00961 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PMLHKFCF_00962 3.7e-107 pncA Q Isochorismatase family
PMLHKFCF_00963 2.7e-132
PMLHKFCF_00964 8.7e-125 skfE V ABC transporter
PMLHKFCF_00965 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
PMLHKFCF_00966 1.2e-45 S Enterocin A Immunity
PMLHKFCF_00967 3.8e-173 D Alpha beta
PMLHKFCF_00968 0.0 pepF2 E Oligopeptidase F
PMLHKFCF_00969 1.3e-72 K Transcriptional regulator
PMLHKFCF_00970 2.3e-164
PMLHKFCF_00971 1.3e-57
PMLHKFCF_00972 6.5e-47
PMLHKFCF_00973 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PMLHKFCF_00974 9.8e-28
PMLHKFCF_00975 8.4e-145 yjfP S Dienelactone hydrolase family
PMLHKFCF_00976 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
PMLHKFCF_00977 1.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PMLHKFCF_00978 5.2e-47
PMLHKFCF_00979 1.7e-45
PMLHKFCF_00980 5e-82 yybC S Protein of unknown function (DUF2798)
PMLHKFCF_00981 3.7e-73
PMLHKFCF_00982 4e-60
PMLHKFCF_00983 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
PMLHKFCF_00984 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
PMLHKFCF_00985 1.6e-79 uspA T universal stress protein
PMLHKFCF_00986 1.3e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PMLHKFCF_00987 1.7e-48 K Cro/C1-type HTH DNA-binding domain
PMLHKFCF_00988 3.3e-21 S Protein of unknown function (DUF2929)
PMLHKFCF_00989 2.3e-223 lsgC M Glycosyl transferases group 1
PMLHKFCF_00990 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PMLHKFCF_00991 2.3e-164 S Putative esterase
PMLHKFCF_00992 2.4e-130 gntR2 K Transcriptional regulator
PMLHKFCF_00993 4.5e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PMLHKFCF_00994 1.5e-138
PMLHKFCF_00995 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PMLHKFCF_00996 5.5e-138 rrp8 K LytTr DNA-binding domain
PMLHKFCF_00997 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
PMLHKFCF_00998 7.7e-61
PMLHKFCF_00999 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
PMLHKFCF_01000 4.4e-58
PMLHKFCF_01001 1.2e-239 yhdP S Transporter associated domain
PMLHKFCF_01002 4.9e-87 nrdI F Belongs to the NrdI family
PMLHKFCF_01003 2.9e-269 yjcE P Sodium proton antiporter
PMLHKFCF_01004 2.8e-213 yttB EGP Major facilitator Superfamily
PMLHKFCF_01005 5e-63 K helix_turn_helix, mercury resistance
PMLHKFCF_01006 3e-30 C Zinc-binding dehydrogenase
PMLHKFCF_01007 1.9e-127 C Zinc-binding dehydrogenase
PMLHKFCF_01008 8.5e-57 S SdpI/YhfL protein family
PMLHKFCF_01009 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PMLHKFCF_01010 3.6e-260 gabR K Bacterial regulatory proteins, gntR family
PMLHKFCF_01011 5e-218 patA 2.6.1.1 E Aminotransferase
PMLHKFCF_01012 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMLHKFCF_01013 3e-18
PMLHKFCF_01014 1.7e-126 S membrane transporter protein
PMLHKFCF_01015 7.3e-161 mleR K LysR family
PMLHKFCF_01016 5.6e-115 ylbE GM NAD(P)H-binding
PMLHKFCF_01017 8.2e-96 wecD K Acetyltransferase (GNAT) family
PMLHKFCF_01018 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PMLHKFCF_01019 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PMLHKFCF_01020 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
PMLHKFCF_01021 2.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PMLHKFCF_01022 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PMLHKFCF_01023 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PMLHKFCF_01024 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PMLHKFCF_01025 7.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PMLHKFCF_01026 6.4e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PMLHKFCF_01027 1.6e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PMLHKFCF_01028 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PMLHKFCF_01029 1e-298 pucR QT Purine catabolism regulatory protein-like family
PMLHKFCF_01030 2.7e-236 pbuX F xanthine permease
PMLHKFCF_01031 2.4e-221 pbuG S Permease family
PMLHKFCF_01032 5.6e-161 GM NmrA-like family
PMLHKFCF_01033 6.5e-156 T EAL domain
PMLHKFCF_01034 2.6e-94
PMLHKFCF_01035 9.2e-253 pgaC GT2 M Glycosyl transferase
PMLHKFCF_01036 1e-122 2.1.1.14 E Methionine synthase
PMLHKFCF_01037 2.1e-214 purD 6.3.4.13 F Belongs to the GARS family
PMLHKFCF_01038 2.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PMLHKFCF_01039 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PMLHKFCF_01040 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PMLHKFCF_01041 2.1e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PMLHKFCF_01042 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PMLHKFCF_01043 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PMLHKFCF_01044 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PMLHKFCF_01045 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PMLHKFCF_01046 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PMLHKFCF_01047 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PMLHKFCF_01048 4.3e-223 XK27_09615 1.3.5.4 S reductase
PMLHKFCF_01049 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
PMLHKFCF_01050 3.2e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
PMLHKFCF_01051 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
PMLHKFCF_01052 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
PMLHKFCF_01053 8.3e-148 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_01054 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
PMLHKFCF_01055 1.7e-139 cysA V ABC transporter, ATP-binding protein
PMLHKFCF_01056 0.0 V FtsX-like permease family
PMLHKFCF_01057 7.4e-40
PMLHKFCF_01058 7.9e-61 gntR1 K Transcriptional regulator, GntR family
PMLHKFCF_01059 6.9e-164 V ABC transporter, ATP-binding protein
PMLHKFCF_01060 5.1e-137
PMLHKFCF_01061 1.9e-80 uspA T universal stress protein
PMLHKFCF_01062 4e-34
PMLHKFCF_01063 5.5e-71 gtcA S Teichoic acid glycosylation protein
PMLHKFCF_01064 1.1e-88
PMLHKFCF_01065 3.2e-50
PMLHKFCF_01067 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
PMLHKFCF_01068 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
PMLHKFCF_01069 5.4e-118
PMLHKFCF_01070 1.5e-52
PMLHKFCF_01072 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PMLHKFCF_01073 1.1e-281 thrC 4.2.3.1 E Threonine synthase
PMLHKFCF_01074 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
PMLHKFCF_01075 6.1e-11 mcbG S Pentapeptide repeats (8 copies)
PMLHKFCF_01076 2.5e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PMLHKFCF_01077 7.5e-103 3.6.1.13 L Belongs to the Nudix hydrolase family
PMLHKFCF_01078 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
PMLHKFCF_01079 1.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
PMLHKFCF_01080 1.2e-35 XK27_01315 S Protein of unknown function (DUF2829)
PMLHKFCF_01081 1.4e-211 S Bacterial protein of unknown function (DUF871)
PMLHKFCF_01082 2.1e-232 S Sterol carrier protein domain
PMLHKFCF_01083 3.6e-88 niaR S 3H domain
PMLHKFCF_01084 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PMLHKFCF_01085 2.8e-117 K Transcriptional regulator
PMLHKFCF_01086 1.1e-151 V ABC transporter
PMLHKFCF_01087 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
PMLHKFCF_01088 4.8e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
PMLHKFCF_01089 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLHKFCF_01090 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLHKFCF_01091 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
PMLHKFCF_01092 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PMLHKFCF_01093 9.9e-129 gntR K UTRA
PMLHKFCF_01094 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
PMLHKFCF_01095 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PMLHKFCF_01096 1.8e-81
PMLHKFCF_01097 9.8e-152 S hydrolase
PMLHKFCF_01098 2.3e-179 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PMLHKFCF_01099 1.4e-151 EG EamA-like transporter family
PMLHKFCF_01100 1.9e-175 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PMLHKFCF_01101 3.5e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PMLHKFCF_01102 6.5e-232
PMLHKFCF_01103 4.2e-77 fld C Flavodoxin
PMLHKFCF_01104 0.0 M Bacterial Ig-like domain (group 3)
PMLHKFCF_01105 6.2e-149 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
PMLHKFCF_01106 4.1e-283 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
PMLHKFCF_01107 2.7e-32
PMLHKFCF_01108 3e-128 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
PMLHKFCF_01109 6.4e-268 ycaM E amino acid
PMLHKFCF_01110 8.7e-78 K Winged helix DNA-binding domain
PMLHKFCF_01111 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
PMLHKFCF_01112 1.1e-161 akr5f 1.1.1.346 S reductase
PMLHKFCF_01113 3.9e-162 K Transcriptional regulator
PMLHKFCF_01115 7e-33
PMLHKFCF_01117 5.4e-212 livJ E Receptor family ligand binding region
PMLHKFCF_01118 2.1e-149 livH U Branched-chain amino acid transport system / permease component
PMLHKFCF_01119 5.3e-141 livM E Branched-chain amino acid transport system / permease component
PMLHKFCF_01120 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
PMLHKFCF_01121 3.3e-124 livF E ABC transporter
PMLHKFCF_01122 1.8e-31 cp12 S Domain in cystathionine beta-synthase and other proteins.
PMLHKFCF_01123 5.3e-63 acuB S Domain in cystathionine beta-synthase and other proteins.
PMLHKFCF_01124 2.3e-91 S WxL domain surface cell wall-binding
PMLHKFCF_01125 2.5e-189 S Cell surface protein
PMLHKFCF_01126 7.3e-62
PMLHKFCF_01127 1e-260
PMLHKFCF_01128 1.5e-167 XK27_00670 S ABC transporter
PMLHKFCF_01129 5.6e-154 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
PMLHKFCF_01130 2.9e-117 cmpC S ATPases associated with a variety of cellular activities
PMLHKFCF_01131 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
PMLHKFCF_01132 1.3e-119 drgA C Nitroreductase family
PMLHKFCF_01133 3e-121 yceE S haloacid dehalogenase-like hydrolase
PMLHKFCF_01134 7.1e-159 ccpB 5.1.1.1 K lacI family
PMLHKFCF_01135 5e-93 rmaB K Transcriptional regulator, MarR family
PMLHKFCF_01136 2.4e-187 lmrA 3.6.3.44 V ABC transporter
PMLHKFCF_01137 7.6e-132 lmrA 3.6.3.44 V ABC transporter
PMLHKFCF_01138 5.6e-89
PMLHKFCF_01139 0.0 ybfG M peptidoglycan-binding domain-containing protein
PMLHKFCF_01140 4.2e-161 ypbG 2.7.1.2 GK ROK family
PMLHKFCF_01141 6.9e-47 3.6.4.12 K HxlR-like helix-turn-helix
PMLHKFCF_01142 2.5e-112 K Transcriptional regulator C-terminal region
PMLHKFCF_01143 1.7e-176 4.1.1.52 S Amidohydrolase
PMLHKFCF_01144 1.3e-128 E lipolytic protein G-D-S-L family
PMLHKFCF_01145 1.1e-159 yicL EG EamA-like transporter family
PMLHKFCF_01146 1.1e-38 sdrF M Collagen binding domain
PMLHKFCF_01147 2.5e-269 I acetylesterase activity
PMLHKFCF_01148 2.6e-176 S Phosphotransferase system, EIIC
PMLHKFCF_01149 1.7e-15 aroD S Alpha/beta hydrolase family
PMLHKFCF_01150 8.3e-108 aroD S Alpha/beta hydrolase family
PMLHKFCF_01151 3.2e-37
PMLHKFCF_01153 2.8e-134 S zinc-ribbon domain
PMLHKFCF_01154 1.5e-264 S response to antibiotic
PMLHKFCF_01155 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
PMLHKFCF_01156 2.4e-243 P Sodium:sulfate symporter transmembrane region
PMLHKFCF_01157 1.2e-163 K LysR substrate binding domain
PMLHKFCF_01158 2.9e-70
PMLHKFCF_01159 4.9e-22
PMLHKFCF_01160 5.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMLHKFCF_01161 2.6e-191 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PMLHKFCF_01162 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PMLHKFCF_01163 2e-80
PMLHKFCF_01164 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PMLHKFCF_01165 3.2e-103 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PMLHKFCF_01166 6.8e-127 yliE T EAL domain
PMLHKFCF_01167 1.2e-102 2.7.7.65 T Diguanylate cyclase, GGDEF domain
PMLHKFCF_01168 3.9e-11 ica2 GT2 M Glycosyl transferase family group 2
PMLHKFCF_01169 1.2e-103
PMLHKFCF_01170 1.1e-172
PMLHKFCF_01171 0.0 typA T GTP-binding protein TypA
PMLHKFCF_01172 3.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PMLHKFCF_01173 3.3e-46 yktA S Belongs to the UPF0223 family
PMLHKFCF_01174 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
PMLHKFCF_01175 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
PMLHKFCF_01176 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PMLHKFCF_01177 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PMLHKFCF_01178 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PMLHKFCF_01179 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PMLHKFCF_01180 1.6e-85
PMLHKFCF_01181 3.1e-33 ykzG S Belongs to the UPF0356 family
PMLHKFCF_01182 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PMLHKFCF_01183 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PMLHKFCF_01184 1.7e-28
PMLHKFCF_01185 2.6e-107 mltD CBM50 M NlpC P60 family protein
PMLHKFCF_01186 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMLHKFCF_01187 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PMLHKFCF_01188 1.6e-120 S Repeat protein
PMLHKFCF_01189 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PMLHKFCF_01190 1.6e-266 N domain, Protein
PMLHKFCF_01191 1.9e-192 S Bacterial protein of unknown function (DUF916)
PMLHKFCF_01192 2.3e-120 N WxL domain surface cell wall-binding
PMLHKFCF_01193 2.6e-115 ktrA P domain protein
PMLHKFCF_01194 1.3e-241 ktrB P Potassium uptake protein
PMLHKFCF_01195 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PMLHKFCF_01196 4.9e-57 XK27_04120 S Putative amino acid metabolism
PMLHKFCF_01197 2.6e-214 iscS 2.8.1.7 E Aminotransferase class V
PMLHKFCF_01198 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PMLHKFCF_01199 4.6e-28
PMLHKFCF_01200 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PMLHKFCF_01201 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PMLHKFCF_01202 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PMLHKFCF_01203 1.2e-86 divIVA D DivIVA domain protein
PMLHKFCF_01204 3.4e-146 ylmH S S4 domain protein
PMLHKFCF_01205 1.2e-36 yggT S YGGT family
PMLHKFCF_01206 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PMLHKFCF_01207 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PMLHKFCF_01208 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PMLHKFCF_01209 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PMLHKFCF_01210 3.4e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PMLHKFCF_01211 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PMLHKFCF_01212 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PMLHKFCF_01213 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PMLHKFCF_01214 7.5e-54 ftsL D Cell division protein FtsL
PMLHKFCF_01215 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PMLHKFCF_01216 1.9e-77 mraZ K Belongs to the MraZ family
PMLHKFCF_01217 1.9e-62 S Protein of unknown function (DUF3397)
PMLHKFCF_01218 1.6e-174 corA P CorA-like Mg2+ transporter protein
PMLHKFCF_01219 7e-40
PMLHKFCF_01221 1.3e-249 EGP Major facilitator Superfamily
PMLHKFCF_01222 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
PMLHKFCF_01223 4.7e-83 cvpA S Colicin V production protein
PMLHKFCF_01224 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PMLHKFCF_01225 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PMLHKFCF_01226 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
PMLHKFCF_01227 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PMLHKFCF_01228 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
PMLHKFCF_01229 2.3e-212 folP 2.5.1.15 H dihydropteroate synthase
PMLHKFCF_01230 6.5e-96 tag 3.2.2.20 L glycosylase
PMLHKFCF_01231 2.6e-19
PMLHKFCF_01232 2.7e-160 czcD P cation diffusion facilitator family transporter
PMLHKFCF_01233 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
PMLHKFCF_01234 3e-116 hly S protein, hemolysin III
PMLHKFCF_01235 1.1e-44 qacH U Small Multidrug Resistance protein
PMLHKFCF_01236 5.8e-59 qacC P Small Multidrug Resistance protein
PMLHKFCF_01237 1.3e-215 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
PMLHKFCF_01238 5.3e-179 K AI-2E family transporter
PMLHKFCF_01239 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PMLHKFCF_01240 0.0 kup P Transport of potassium into the cell
PMLHKFCF_01242 2.3e-257 yhdG E C-terminus of AA_permease
PMLHKFCF_01243 2.1e-82
PMLHKFCF_01245 4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMLHKFCF_01246 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
PMLHKFCF_01247 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PMLHKFCF_01248 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PMLHKFCF_01249 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PMLHKFCF_01250 9.8e-55 S Enterocin A Immunity
PMLHKFCF_01251 1.9e-258 gor 1.8.1.7 C Glutathione reductase
PMLHKFCF_01252 2.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PMLHKFCF_01253 4.2e-183 D Alpha beta
PMLHKFCF_01254 6.9e-164 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
PMLHKFCF_01255 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
PMLHKFCF_01256 5e-117 yugP S Putative neutral zinc metallopeptidase
PMLHKFCF_01257 4.1e-25
PMLHKFCF_01258 7.1e-145 DegV S EDD domain protein, DegV family
PMLHKFCF_01259 7.3e-127 lrgB M LrgB-like family
PMLHKFCF_01260 5.1e-64 lrgA S LrgA family
PMLHKFCF_01261 3.8e-104 J Acetyltransferase (GNAT) domain
PMLHKFCF_01262 2.1e-78 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
PMLHKFCF_01263 2.1e-60 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
PMLHKFCF_01264 5.4e-36 S Phospholipase_D-nuclease N-terminal
PMLHKFCF_01265 7.1e-59 S Enterocin A Immunity
PMLHKFCF_01266 1.3e-87 perR P Belongs to the Fur family
PMLHKFCF_01267 8.4e-105
PMLHKFCF_01268 7.9e-238 S module of peptide synthetase
PMLHKFCF_01269 1.1e-77 S NADPH-dependent FMN reductase
PMLHKFCF_01270 1.4e-08
PMLHKFCF_01271 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
PMLHKFCF_01272 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PMLHKFCF_01273 9e-156 1.6.5.2 GM NmrA-like family
PMLHKFCF_01274 2e-77 merR K MerR family regulatory protein
PMLHKFCF_01275 4.7e-74 K Bacterial regulatory proteins, tetR family
PMLHKFCF_01276 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PMLHKFCF_01277 5.5e-106
PMLHKFCF_01278 9.3e-106 GBS0088 S Nucleotidyltransferase
PMLHKFCF_01279 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PMLHKFCF_01280 9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PMLHKFCF_01281 6.3e-75 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
PMLHKFCF_01282 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PMLHKFCF_01283 0.0 S membrane
PMLHKFCF_01284 1.7e-19 S NUDIX domain
PMLHKFCF_01285 2.4e-270 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PMLHKFCF_01286 1.7e-15 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PMLHKFCF_01287 6.1e-185 ykoT GT2 M Glycosyl transferase family 2
PMLHKFCF_01288 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PMLHKFCF_01289 1.7e-99
PMLHKFCF_01290 0.0 1.3.5.4 C FAD binding domain
PMLHKFCF_01291 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
PMLHKFCF_01292 7.6e-177 K LysR substrate binding domain
PMLHKFCF_01293 3.1e-181 3.4.21.102 M Peptidase family S41
PMLHKFCF_01294 2.1e-213
PMLHKFCF_01295 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
PMLHKFCF_01296 0.0 L AAA domain
PMLHKFCF_01297 5.7e-233 yhaO L Ser Thr phosphatase family protein
PMLHKFCF_01298 1e-54 yheA S Belongs to the UPF0342 family
PMLHKFCF_01299 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PMLHKFCF_01300 2.9e-12
PMLHKFCF_01301 4.4e-77 argR K Regulates arginine biosynthesis genes
PMLHKFCF_01302 7.1e-214 arcT 2.6.1.1 E Aminotransferase
PMLHKFCF_01303 1.4e-102 argO S LysE type translocator
PMLHKFCF_01304 2.4e-283 ydfD K Alanine-glyoxylate amino-transferase
PMLHKFCF_01305 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PMLHKFCF_01306 1.5e-112 M ErfK YbiS YcfS YnhG
PMLHKFCF_01307 9.5e-209 EGP Major facilitator Superfamily
PMLHKFCF_01308 5.2e-289 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLHKFCF_01309 8.4e-214 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLHKFCF_01310 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PMLHKFCF_01311 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PMLHKFCF_01312 2.4e-62 S Domain of unknown function (DUF3284)
PMLHKFCF_01313 0.0 K PRD domain
PMLHKFCF_01314 1.1e-105
PMLHKFCF_01315 0.0 yhcA V MacB-like periplasmic core domain
PMLHKFCF_01316 1.4e-81
PMLHKFCF_01317 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PMLHKFCF_01318 1.5e-77 elaA S Acetyltransferase (GNAT) domain
PMLHKFCF_01321 1.9e-31
PMLHKFCF_01322 2.1e-244 dinF V MatE
PMLHKFCF_01323 3.9e-75 S Psort location Cytoplasmic, score
PMLHKFCF_01324 6e-97 S Domain of unknown function (DUF4352)
PMLHKFCF_01325 2.9e-23 S Protein of unknown function (DUF4064)
PMLHKFCF_01326 3.2e-200 KLT Protein tyrosine kinase
PMLHKFCF_01327 3.9e-162
PMLHKFCF_01328 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PMLHKFCF_01329 2.3e-81
PMLHKFCF_01330 1.7e-210 xylR GK ROK family
PMLHKFCF_01331 4.9e-172 K AI-2E family transporter
PMLHKFCF_01332 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PMLHKFCF_01333 8.8e-40
PMLHKFCF_01334 4.6e-91 V ABC transporter, ATP-binding protein
PMLHKFCF_01335 5.7e-58 S ABC-2 family transporter protein
PMLHKFCF_01336 1.2e-90 S ABC-2 family transporter protein
PMLHKFCF_01337 1.4e-46 K Helix-turn-helix domain
PMLHKFCF_01338 1.6e-202 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PMLHKFCF_01339 2.3e-51 K Helix-turn-helix domain
PMLHKFCF_01340 1e-64 V ABC transporter
PMLHKFCF_01341 3.3e-66
PMLHKFCF_01342 2.2e-41 K HxlR-like helix-turn-helix
PMLHKFCF_01343 1e-107 ydeA S intracellular protease amidase
PMLHKFCF_01344 1.1e-43 S Protein of unknown function (DUF3781)
PMLHKFCF_01345 4.3e-207 S Membrane
PMLHKFCF_01346 6.4e-63 S Protein of unknown function (DUF1093)
PMLHKFCF_01347 4.1e-65
PMLHKFCF_01348 1.6e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLHKFCF_01349 1.2e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLHKFCF_01350 2.4e-114 K UTRA
PMLHKFCF_01351 1.7e-84 dps P Belongs to the Dps family
PMLHKFCF_01352 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
PMLHKFCF_01353 4e-281 1.3.5.4 C FAD binding domain
PMLHKFCF_01354 1.8e-159 K LysR substrate binding domain
PMLHKFCF_01355 5.7e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
PMLHKFCF_01356 2.5e-289 yjcE P Sodium proton antiporter
PMLHKFCF_01357 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PMLHKFCF_01358 8.1e-117 K Bacterial regulatory proteins, tetR family
PMLHKFCF_01359 3.1e-51 NU Mycoplasma protein of unknown function, DUF285
PMLHKFCF_01360 1.6e-106 2.7.7.65 T Diguanylate cyclase, GGDEF domain
PMLHKFCF_01361 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PMLHKFCF_01362 5.6e-39 S Cytochrome B5
PMLHKFCF_01363 1.2e-234
PMLHKFCF_01364 7e-130 treR K UTRA
PMLHKFCF_01365 1.1e-158 I alpha/beta hydrolase fold
PMLHKFCF_01366 1.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
PMLHKFCF_01367 2e-233 yxiO S Vacuole effluxer Atg22 like
PMLHKFCF_01368 1.2e-171 ropB K Helix-turn-helix XRE-family like proteins
PMLHKFCF_01369 3.1e-207 EGP Major facilitator Superfamily
PMLHKFCF_01370 0.0 uvrA3 L excinuclease ABC
PMLHKFCF_01371 0.0 S Predicted membrane protein (DUF2207)
PMLHKFCF_01372 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
PMLHKFCF_01373 1.2e-307 ybiT S ABC transporter, ATP-binding protein
PMLHKFCF_01374 1.1e-223 S CAAX protease self-immunity
PMLHKFCF_01375 2.2e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
PMLHKFCF_01376 6.3e-99 speG J Acetyltransferase (GNAT) domain
PMLHKFCF_01377 1.7e-139 endA F DNA RNA non-specific endonuclease
PMLHKFCF_01378 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
PMLHKFCF_01379 1.5e-95 K Transcriptional regulator (TetR family)
PMLHKFCF_01380 1e-197 yhgE V domain protein
PMLHKFCF_01385 1.3e-246 EGP Major facilitator Superfamily
PMLHKFCF_01386 0.0 mdlA V ABC transporter
PMLHKFCF_01387 0.0 mdlB V ABC transporter
PMLHKFCF_01389 1.2e-194 C Aldo/keto reductase family
PMLHKFCF_01390 7.4e-102 M Protein of unknown function (DUF3737)
PMLHKFCF_01391 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
PMLHKFCF_01392 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PMLHKFCF_01393 0.0 lacS G Transporter
PMLHKFCF_01394 4.5e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PMLHKFCF_01395 1.1e-173 galR K Transcriptional regulator
PMLHKFCF_01396 3.1e-192 C Aldo keto reductase family protein
PMLHKFCF_01397 5.2e-65 S pyridoxamine 5-phosphate
PMLHKFCF_01398 0.0 1.3.5.4 C FAD binding domain
PMLHKFCF_01399 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PMLHKFCF_01400 2.1e-129 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PMLHKFCF_01401 2.7e-214 ydiM G Transporter
PMLHKFCF_01402 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PMLHKFCF_01403 3.4e-163 K Transcriptional regulator, LysR family
PMLHKFCF_01404 1.8e-210 ydiN G Major Facilitator Superfamily
PMLHKFCF_01405 1e-63
PMLHKFCF_01406 3.4e-154 estA S Putative esterase
PMLHKFCF_01407 1.2e-134 K UTRA domain
PMLHKFCF_01408 6.2e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLHKFCF_01409 3.7e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PMLHKFCF_01410 2.2e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
PMLHKFCF_01411 1.1e-211 S Bacterial protein of unknown function (DUF871)
PMLHKFCF_01412 1.4e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLHKFCF_01413 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
PMLHKFCF_01414 1.3e-154 licT K CAT RNA binding domain
PMLHKFCF_01415 1.7e-292 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLHKFCF_01416 5.5e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLHKFCF_01417 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
PMLHKFCF_01418 3.8e-159 licT K CAT RNA binding domain
PMLHKFCF_01419 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
PMLHKFCF_01420 1.1e-173 K Transcriptional regulator, LacI family
PMLHKFCF_01421 2.3e-270 G Major Facilitator
PMLHKFCF_01422 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
PMLHKFCF_01423 9.2e-131 znuB U ABC 3 transport family
PMLHKFCF_01424 9.8e-129 fhuC 3.6.3.35 P ABC transporter
PMLHKFCF_01425 1.3e-181 S Prolyl oligopeptidase family
PMLHKFCF_01426 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PMLHKFCF_01427 3.2e-37 veg S Biofilm formation stimulator VEG
PMLHKFCF_01428 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PMLHKFCF_01429 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PMLHKFCF_01430 1.5e-146 tatD L hydrolase, TatD family
PMLHKFCF_01432 1.3e-83 mutR K sequence-specific DNA binding
PMLHKFCF_01433 2e-214 bcr1 EGP Major facilitator Superfamily
PMLHKFCF_01434 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PMLHKFCF_01435 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
PMLHKFCF_01436 2e-160 yunF F Protein of unknown function DUF72
PMLHKFCF_01437 2.5e-132 cobB K SIR2 family
PMLHKFCF_01438 2.7e-177
PMLHKFCF_01439 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PMLHKFCF_01440 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PMLHKFCF_01441 8.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMLHKFCF_01442 2.8e-58 chpA T PemK-like, MazF-like toxin of type II toxin-antitoxin system
PMLHKFCF_01443 4.8e-34
PMLHKFCF_01444 4.9e-75 S Domain of unknown function (DUF3284)
PMLHKFCF_01445 3.9e-24
PMLHKFCF_01446 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLHKFCF_01447 9e-130 K UbiC transcription regulator-associated domain protein
PMLHKFCF_01448 5.9e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMLHKFCF_01449 2.1e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PMLHKFCF_01450 0.0 helD 3.6.4.12 L DNA helicase
PMLHKFCF_01451 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
PMLHKFCF_01452 9.6e-113 S CAAX protease self-immunity
PMLHKFCF_01453 1.2e-110 V CAAX protease self-immunity
PMLHKFCF_01454 7.4e-118 ypbD S CAAX protease self-immunity
PMLHKFCF_01455 1.4e-108 S CAAX protease self-immunity
PMLHKFCF_01456 7.5e-242 mesE M Transport protein ComB
PMLHKFCF_01457 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PMLHKFCF_01458 5.5e-13
PMLHKFCF_01459 2.4e-22 plnF
PMLHKFCF_01460 2.2e-129 S CAAX protease self-immunity
PMLHKFCF_01461 2e-45 ygbF S Sugar efflux transporter for intercellular exchange
PMLHKFCF_01462 4.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PMLHKFCF_01463 0.0 rafA 3.2.1.22 G alpha-galactosidase
PMLHKFCF_01464 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
PMLHKFCF_01465 1.5e-304 scrB 3.2.1.26 GH32 G invertase
PMLHKFCF_01466 5.9e-172 scrR K Transcriptional regulator, LacI family
PMLHKFCF_01467 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PMLHKFCF_01468 1.4e-164 3.5.1.10 C nadph quinone reductase
PMLHKFCF_01469 1.1e-217 nhaC C Na H antiporter NhaC
PMLHKFCF_01470 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PMLHKFCF_01471 2.9e-128 mleR K LysR substrate binding domain
PMLHKFCF_01472 5e-27 mleR K LysR substrate binding domain
PMLHKFCF_01473 0.0 3.6.4.13 M domain protein
PMLHKFCF_01475 2.1e-157 hipB K Helix-turn-helix
PMLHKFCF_01476 0.0 oppA E ABC transporter, substratebinding protein
PMLHKFCF_01477 1.8e-309 oppA E ABC transporter, substratebinding protein
PMLHKFCF_01478 5.9e-79 yiaC K Acetyltransferase (GNAT) domain
PMLHKFCF_01479 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMLHKFCF_01480 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PMLHKFCF_01481 3e-113 pgm1 G phosphoglycerate mutase
PMLHKFCF_01482 7.2e-178 yghZ C Aldo keto reductase family protein
PMLHKFCF_01483 4.9e-34
PMLHKFCF_01484 1.3e-60 S Domain of unknown function (DU1801)
PMLHKFCF_01485 2.9e-162 FbpA K Domain of unknown function (DUF814)
PMLHKFCF_01486 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMLHKFCF_01488 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMLHKFCF_01489 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMLHKFCF_01490 2.6e-212 S ATPases associated with a variety of cellular activities
PMLHKFCF_01491 2.9e-253 S Bacterial membrane protein YfhO
PMLHKFCF_01492 1.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_01493 2.1e-168 K LysR substrate binding domain
PMLHKFCF_01494 1.9e-236 EK Aminotransferase, class I
PMLHKFCF_01495 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PMLHKFCF_01496 8.1e-123 tcyB E ABC transporter
PMLHKFCF_01497 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMLHKFCF_01498 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PMLHKFCF_01499 5.8e-79 KT response to antibiotic
PMLHKFCF_01500 9.8e-52 K Transcriptional regulator
PMLHKFCF_01501 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
PMLHKFCF_01502 2.1e-126 S Putative adhesin
PMLHKFCF_01503 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
PMLHKFCF_01504 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PMLHKFCF_01505 4.1e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
PMLHKFCF_01506 2.6e-205 S DUF218 domain
PMLHKFCF_01507 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
PMLHKFCF_01508 1.4e-116 ybbL S ABC transporter, ATP-binding protein
PMLHKFCF_01509 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PMLHKFCF_01510 9.4e-77
PMLHKFCF_01511 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
PMLHKFCF_01512 1.1e-147 cof S haloacid dehalogenase-like hydrolase
PMLHKFCF_01513 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PMLHKFCF_01514 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
PMLHKFCF_01515 3.7e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
PMLHKFCF_01516 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
PMLHKFCF_01517 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PMLHKFCF_01518 2.9e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMLHKFCF_01521 3e-252 dtpT U amino acid peptide transporter
PMLHKFCF_01522 1.3e-150 yjjH S Calcineurin-like phosphoesterase
PMLHKFCF_01526 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
PMLHKFCF_01527 2.5e-53 S Cupin domain
PMLHKFCF_01528 1.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
PMLHKFCF_01529 4.7e-194 ybiR P Citrate transporter
PMLHKFCF_01530 1.6e-151 pnuC H nicotinamide mononucleotide transporter
PMLHKFCF_01531 3.8e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PMLHKFCF_01532 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PMLHKFCF_01533 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
PMLHKFCF_01534 8.7e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PMLHKFCF_01535 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PMLHKFCF_01536 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PMLHKFCF_01537 0.0 pacL 3.6.3.8 P P-type ATPase
PMLHKFCF_01538 3.4e-71
PMLHKFCF_01539 0.0 yhgF K Tex-like protein N-terminal domain protein
PMLHKFCF_01540 3.7e-81 ydcK S Belongs to the SprT family
PMLHKFCF_01541 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PMLHKFCF_01542 2.9e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PMLHKFCF_01544 7.4e-152 G Peptidase_C39 like family
PMLHKFCF_01545 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PMLHKFCF_01546 3.4e-133 manY G PTS system
PMLHKFCF_01547 4.4e-169 manN G system, mannose fructose sorbose family IID component
PMLHKFCF_01548 4.7e-64 S Domain of unknown function (DUF956)
PMLHKFCF_01549 0.0 levR K Sigma-54 interaction domain
PMLHKFCF_01550 4.3e-71 pts10A 2.7.1.191 G PTS system fructose IIA component
PMLHKFCF_01551 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
PMLHKFCF_01552 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PMLHKFCF_01553 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
PMLHKFCF_01554 1.5e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
PMLHKFCF_01555 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PMLHKFCF_01556 4.3e-133 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
PMLHKFCF_01557 5.3e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PMLHKFCF_01558 5.6e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PMLHKFCF_01559 8.3e-177 EG EamA-like transporter family
PMLHKFCF_01560 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PMLHKFCF_01561 5.2e-113 zmp2 O Zinc-dependent metalloprotease
PMLHKFCF_01562 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
PMLHKFCF_01563 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PMLHKFCF_01564 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
PMLHKFCF_01565 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PMLHKFCF_01566 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PMLHKFCF_01567 3.7e-205 yacL S domain protein
PMLHKFCF_01568 2.6e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PMLHKFCF_01569 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMLHKFCF_01570 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PMLHKFCF_01571 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMLHKFCF_01572 7.7e-97 yacP S YacP-like NYN domain
PMLHKFCF_01573 2.4e-101 sigH K Sigma-70 region 2
PMLHKFCF_01574 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PMLHKFCF_01575 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PMLHKFCF_01576 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
PMLHKFCF_01577 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_01578 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PMLHKFCF_01579 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PMLHKFCF_01580 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PMLHKFCF_01581 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PMLHKFCF_01582 9.3e-178 F DNA/RNA non-specific endonuclease
PMLHKFCF_01583 1.2e-38 L nuclease
PMLHKFCF_01584 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PMLHKFCF_01585 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
PMLHKFCF_01586 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMLHKFCF_01587 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMLHKFCF_01588 6.5e-37 nrdH O Glutaredoxin
PMLHKFCF_01589 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
PMLHKFCF_01590 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PMLHKFCF_01591 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PMLHKFCF_01592 1.7e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PMLHKFCF_01593 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PMLHKFCF_01594 2.2e-38 yaaL S Protein of unknown function (DUF2508)
PMLHKFCF_01595 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PMLHKFCF_01596 2.4e-53 yaaQ S Cyclic-di-AMP receptor
PMLHKFCF_01597 3.3e-186 holB 2.7.7.7 L DNA polymerase III
PMLHKFCF_01598 1e-57 yabA L Involved in initiation control of chromosome replication
PMLHKFCF_01599 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PMLHKFCF_01600 1.1e-147 fat 3.1.2.21 I Acyl-ACP thioesterase
PMLHKFCF_01601 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PMLHKFCF_01602 7.2e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
PMLHKFCF_01603 8.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
PMLHKFCF_01604 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
PMLHKFCF_01605 2.5e-136 phnE 3.6.1.63 U Phosphonate ABC transporter permease
PMLHKFCF_01606 2.8e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PMLHKFCF_01607 5.1e-190 phnD P Phosphonate ABC transporter
PMLHKFCF_01608 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PMLHKFCF_01609 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PMLHKFCF_01610 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PMLHKFCF_01611 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PMLHKFCF_01612 3.3e-307 uup S ABC transporter, ATP-binding protein
PMLHKFCF_01613 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PMLHKFCF_01614 6.1e-109 ydiL S CAAX protease self-immunity
PMLHKFCF_01615 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PMLHKFCF_01616 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PMLHKFCF_01617 0.0 ydaO E amino acid
PMLHKFCF_01618 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
PMLHKFCF_01619 4.3e-145 pstS P Phosphate
PMLHKFCF_01620 1.7e-114 yvyE 3.4.13.9 S YigZ family
PMLHKFCF_01621 9.6e-258 comFA L Helicase C-terminal domain protein
PMLHKFCF_01622 7.5e-126 comFC S Competence protein
PMLHKFCF_01623 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PMLHKFCF_01624 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PMLHKFCF_01625 4.1e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PMLHKFCF_01626 7.9e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
PMLHKFCF_01627 1.5e-132 K response regulator
PMLHKFCF_01628 3.5e-250 phoR 2.7.13.3 T Histidine kinase
PMLHKFCF_01629 2.1e-149 pstS P Phosphate
PMLHKFCF_01630 2.6e-161 pstC P probably responsible for the translocation of the substrate across the membrane
PMLHKFCF_01631 1.5e-155 pstA P Phosphate transport system permease protein PstA
PMLHKFCF_01632 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PMLHKFCF_01633 3.3e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PMLHKFCF_01634 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
PMLHKFCF_01635 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
PMLHKFCF_01636 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PMLHKFCF_01637 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PMLHKFCF_01638 2.3e-164 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PMLHKFCF_01639 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PMLHKFCF_01640 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PMLHKFCF_01641 1.9e-124 yliE T Putative diguanylate phosphodiesterase
PMLHKFCF_01642 3.9e-270 nox C NADH oxidase
PMLHKFCF_01643 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PMLHKFCF_01644 2e-109 yviA S Protein of unknown function (DUF421)
PMLHKFCF_01645 1.1e-61 S Protein of unknown function (DUF3290)
PMLHKFCF_01646 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PMLHKFCF_01647 3.3e-132 yliE T Putative diguanylate phosphodiesterase
PMLHKFCF_01648 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PMLHKFCF_01649 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PMLHKFCF_01650 9.2e-212 norA EGP Major facilitator Superfamily
PMLHKFCF_01651 3.6e-117 yfbR S HD containing hydrolase-like enzyme
PMLHKFCF_01652 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PMLHKFCF_01653 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PMLHKFCF_01654 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PMLHKFCF_01655 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PMLHKFCF_01656 7.9e-263 argH 4.3.2.1 E argininosuccinate lyase
PMLHKFCF_01657 3.5e-86 S Short repeat of unknown function (DUF308)
PMLHKFCF_01658 1.1e-161 rapZ S Displays ATPase and GTPase activities
PMLHKFCF_01659 1.9e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PMLHKFCF_01660 3.7e-168 whiA K May be required for sporulation
PMLHKFCF_01661 9.9e-289 oppA E ABC transporter, substratebinding protein
PMLHKFCF_01662 7.4e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMLHKFCF_01663 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PMLHKFCF_01665 4.2e-245 rpoN K Sigma-54 factor, core binding domain
PMLHKFCF_01666 7.3e-189 cggR K Putative sugar-binding domain
PMLHKFCF_01667 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PMLHKFCF_01668 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PMLHKFCF_01669 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PMLHKFCF_01670 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PMLHKFCF_01671 2e-131
PMLHKFCF_01672 6.6e-295 clcA P chloride
PMLHKFCF_01673 3.5e-30 secG U Preprotein translocase
PMLHKFCF_01674 5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
PMLHKFCF_01675 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PMLHKFCF_01676 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PMLHKFCF_01677 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
PMLHKFCF_01678 1.5e-256 glnP P ABC transporter
PMLHKFCF_01679 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMLHKFCF_01680 6.1e-105 yxjI
PMLHKFCF_01681 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
PMLHKFCF_01682 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PMLHKFCF_01683 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PMLHKFCF_01684 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PMLHKFCF_01685 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
PMLHKFCF_01686 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
PMLHKFCF_01687 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
PMLHKFCF_01688 3.9e-162 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
PMLHKFCF_01689 6.2e-168 murB 1.3.1.98 M Cell wall formation
PMLHKFCF_01690 0.0 yjcE P Sodium proton antiporter
PMLHKFCF_01691 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
PMLHKFCF_01692 1e-54 S Protein of unknown function (DUF1361)
PMLHKFCF_01693 6e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PMLHKFCF_01694 1.6e-129 ybbR S YbbR-like protein
PMLHKFCF_01695 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PMLHKFCF_01696 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PMLHKFCF_01697 9.1e-50
PMLHKFCF_01698 3e-08
PMLHKFCF_01700 5.2e-188 rbsR K helix_turn _helix lactose operon repressor
PMLHKFCF_01701 6.7e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMLHKFCF_01702 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PMLHKFCF_01703 2.7e-160 rbsU U ribose uptake protein RbsU
PMLHKFCF_01704 3.8e-145 IQ NAD dependent epimerase/dehydratase family
PMLHKFCF_01705 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
PMLHKFCF_01706 1.1e-86 gutM K Glucitol operon activator protein (GutM)
PMLHKFCF_01707 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
PMLHKFCF_01708 1.5e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
PMLHKFCF_01709 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PMLHKFCF_01710 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PMLHKFCF_01711 8.7e-72 K Transcriptional regulator
PMLHKFCF_01712 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PMLHKFCF_01713 1.1e-130 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PMLHKFCF_01714 5.1e-57 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PMLHKFCF_01716 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
PMLHKFCF_01717 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
PMLHKFCF_01718 1.8e-12
PMLHKFCF_01719 8.7e-160 2.7.13.3 T GHKL domain
PMLHKFCF_01720 7.4e-135 K LytTr DNA-binding domain
PMLHKFCF_01721 4.9e-78 yneH 1.20.4.1 K ArsC family
PMLHKFCF_01722 5.4e-291 katA 1.11.1.6 C Belongs to the catalase family
PMLHKFCF_01723 9e-13 ytgB S Transglycosylase associated protein
PMLHKFCF_01724 3.6e-11
PMLHKFCF_01725 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
PMLHKFCF_01726 1.3e-23 hol S Bacteriophage holin
PMLHKFCF_01727 1.3e-36 S Haemolysin XhlA
PMLHKFCF_01728 2.5e-206 lys M Glycosyl hydrolases family 25
PMLHKFCF_01729 4.7e-20
PMLHKFCF_01730 2.9e-71
PMLHKFCF_01733 2.3e-88
PMLHKFCF_01734 0.0 S Phage minor structural protein
PMLHKFCF_01735 0.0 S Phage tail protein
PMLHKFCF_01736 0.0 D NLP P60 protein
PMLHKFCF_01737 6.6e-24
PMLHKFCF_01738 1.8e-57 S Phage tail assembly chaperone proteins, TAC
PMLHKFCF_01739 3e-103 S Phage tail tube protein
PMLHKFCF_01740 3.5e-56 S Protein of unknown function (DUF806)
PMLHKFCF_01741 5.2e-66 S Bacteriophage HK97-gp10, putative tail-component
PMLHKFCF_01742 1.7e-57 S Phage head-tail joining protein
PMLHKFCF_01743 6.2e-49 S Phage gp6-like head-tail connector protein
PMLHKFCF_01744 7.5e-201 S Phage capsid family
PMLHKFCF_01745 6e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
PMLHKFCF_01746 5.2e-223 S Phage portal protein
PMLHKFCF_01747 2.1e-25 S Protein of unknown function (DUF1056)
PMLHKFCF_01748 0.0 S Phage Terminase
PMLHKFCF_01749 3.6e-79 L Phage terminase, small subunit
PMLHKFCF_01751 6.1e-88 L HNH nucleases
PMLHKFCF_01753 8.2e-65 S Transcriptional regulator, RinA family
PMLHKFCF_01754 1.4e-15
PMLHKFCF_01755 1.4e-55
PMLHKFCF_01756 1.2e-09 S YopX protein
PMLHKFCF_01758 7e-96 2.1.1.37 L C-5 cytosine-specific DNA methylase
PMLHKFCF_01761 3.7e-66 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
PMLHKFCF_01762 3.4e-31 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PMLHKFCF_01763 4.3e-144 yxeH S hydrolase
PMLHKFCF_01764 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PMLHKFCF_01765 8.3e-114 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PMLHKFCF_01766 3.2e-240 ulaA 2.7.1.194 S PTS system sugar-specific permease component
PMLHKFCF_01767 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
PMLHKFCF_01768 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMLHKFCF_01769 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMLHKFCF_01770 1.8e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
PMLHKFCF_01771 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
PMLHKFCF_01772 1.1e-231 gatC G PTS system sugar-specific permease component
PMLHKFCF_01773 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PMLHKFCF_01774 1.5e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMLHKFCF_01775 7e-112 K DeoR C terminal sensor domain
PMLHKFCF_01776 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PMLHKFCF_01777 7.4e-136 K Helix-turn-helix domain, rpiR family
PMLHKFCF_01778 3.7e-72 yueI S Protein of unknown function (DUF1694)
PMLHKFCF_01779 2.6e-38 I alpha/beta hydrolase fold
PMLHKFCF_01780 1.6e-99 I alpha/beta hydrolase fold
PMLHKFCF_01781 1.3e-159 I alpha/beta hydrolase fold
PMLHKFCF_01782 1.7e-271 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PMLHKFCF_01783 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PMLHKFCF_01784 1.6e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
PMLHKFCF_01785 5.4e-153 nanK GK ROK family
PMLHKFCF_01786 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
PMLHKFCF_01787 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PMLHKFCF_01788 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
PMLHKFCF_01789 4.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PMLHKFCF_01790 3.7e-44
PMLHKFCF_01791 3.2e-20 zmp1 O Zinc-dependent metalloprotease
PMLHKFCF_01792 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PMLHKFCF_01793 4.2e-310 mco Q Multicopper oxidase
PMLHKFCF_01794 1.1e-54 ypaA S Protein of unknown function (DUF1304)
PMLHKFCF_01795 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
PMLHKFCF_01796 1.5e-230 flhF N Uncharacterized conserved protein (DUF2075)
PMLHKFCF_01797 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
PMLHKFCF_01798 9.3e-80
PMLHKFCF_01799 2.7e-68 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PMLHKFCF_01800 4.5e-174 rihC 3.2.2.1 F Nucleoside
PMLHKFCF_01801 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
PMLHKFCF_01802 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
PMLHKFCF_01803 1.5e-275 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PMLHKFCF_01804 9.9e-180 proV E ABC transporter, ATP-binding protein
PMLHKFCF_01805 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
PMLHKFCF_01806 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PMLHKFCF_01807 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
PMLHKFCF_01808 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PMLHKFCF_01809 1.1e-235 M domain protein
PMLHKFCF_01810 5.1e-52 U domain, Protein
PMLHKFCF_01811 4.4e-25 S Immunity protein 74
PMLHKFCF_01812 2.3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
PMLHKFCF_01813 1.3e-66 S Iron-sulphur cluster biosynthesis
PMLHKFCF_01814 1.8e-113 S GyrI-like small molecule binding domain
PMLHKFCF_01815 2.4e-187 S Cell surface protein
PMLHKFCF_01816 2.2e-100 S WxL domain surface cell wall-binding
PMLHKFCF_01817 1.1e-62
PMLHKFCF_01818 6.9e-210 NU Mycoplasma protein of unknown function, DUF285
PMLHKFCF_01819 5.9e-117
PMLHKFCF_01820 1e-116 S Haloacid dehalogenase-like hydrolase
PMLHKFCF_01821 2e-61 K Transcriptional regulator, HxlR family
PMLHKFCF_01822 5.1e-210 ytbD EGP Major facilitator Superfamily
PMLHKFCF_01823 1.4e-94 M ErfK YbiS YcfS YnhG
PMLHKFCF_01824 0.0 asnB 6.3.5.4 E Asparagine synthase
PMLHKFCF_01825 8.2e-134 K LytTr DNA-binding domain
PMLHKFCF_01826 4.3e-204 2.7.13.3 T GHKL domain
PMLHKFCF_01827 1.5e-95 fadR K Bacterial regulatory proteins, tetR family
PMLHKFCF_01828 2e-166 GM NmrA-like family
PMLHKFCF_01829 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PMLHKFCF_01830 0.0 M Glycosyl hydrolases family 25
PMLHKFCF_01831 1e-47 S Domain of unknown function (DUF1905)
PMLHKFCF_01832 8.3e-63 hxlR K HxlR-like helix-turn-helix
PMLHKFCF_01833 2.9e-131 ydfG S KR domain
PMLHKFCF_01834 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PMLHKFCF_01835 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PMLHKFCF_01836 2.4e-113 ywnB S NAD(P)H-binding
PMLHKFCF_01837 4.8e-209 brnQ U Component of the transport system for branched-chain amino acids
PMLHKFCF_01839 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
PMLHKFCF_01840 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PMLHKFCF_01841 4.3e-206 XK27_05220 S AI-2E family transporter
PMLHKFCF_01842 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PMLHKFCF_01843 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PMLHKFCF_01844 1.1e-115 cutC P Participates in the control of copper homeostasis
PMLHKFCF_01845 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PMLHKFCF_01846 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PMLHKFCF_01847 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
PMLHKFCF_01848 3.6e-114 yjbH Q Thioredoxin
PMLHKFCF_01849 0.0 pepF E oligoendopeptidase F
PMLHKFCF_01850 2e-180 coiA 3.6.4.12 S Competence protein
PMLHKFCF_01851 2e-13 coiA 3.6.4.12 S Competence protein
PMLHKFCF_01852 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PMLHKFCF_01853 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PMLHKFCF_01854 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
PMLHKFCF_01855 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PMLHKFCF_01865 5.5e-08
PMLHKFCF_01874 3.6e-53 lytE M LysM domain protein
PMLHKFCF_01875 7.4e-67 gcvH E Glycine cleavage H-protein
PMLHKFCF_01876 2.8e-176 sepS16B
PMLHKFCF_01877 1.8e-130
PMLHKFCF_01878 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
PMLHKFCF_01879 6.8e-57
PMLHKFCF_01880 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMLHKFCF_01881 4.9e-24 elaA S GNAT family
PMLHKFCF_01882 8.4e-75 K Transcriptional regulator
PMLHKFCF_01883 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
PMLHKFCF_01884 4.3e-40
PMLHKFCF_01885 1.5e-205 potD P ABC transporter
PMLHKFCF_01886 2.9e-140 potC P ABC transporter permease
PMLHKFCF_01887 4.5e-149 potB P ABC transporter permease
PMLHKFCF_01888 3.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PMLHKFCF_01889 1.3e-96 puuR K Cupin domain
PMLHKFCF_01890 1.1e-83 6.3.3.2 S ASCH
PMLHKFCF_01891 1e-84 K GNAT family
PMLHKFCF_01892 8e-91 K acetyltransferase
PMLHKFCF_01893 8.1e-22
PMLHKFCF_01894 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
PMLHKFCF_01895 2e-163 ytrB V ABC transporter
PMLHKFCF_01896 4.9e-190
PMLHKFCF_01897 1.8e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
PMLHKFCF_01898 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PMLHKFCF_01900 1.5e-239 xylP1 G MFS/sugar transport protein
PMLHKFCF_01901 8.7e-122 qmcA O prohibitin homologues
PMLHKFCF_01902 1.1e-29
PMLHKFCF_01903 6.5e-281 pipD E Dipeptidase
PMLHKFCF_01904 3e-40
PMLHKFCF_01905 5.7e-95 bioY S BioY family
PMLHKFCF_01906 1.1e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PMLHKFCF_01907 1.8e-61 S CHY zinc finger
PMLHKFCF_01908 7.8e-222 mtnE 2.6.1.83 E Aminotransferase
PMLHKFCF_01909 3.8e-218
PMLHKFCF_01910 6e-154 tagG U Transport permease protein
PMLHKFCF_01911 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PMLHKFCF_01912 8.4e-44
PMLHKFCF_01913 2.8e-91 K Transcriptional regulator PadR-like family
PMLHKFCF_01914 1.3e-257 P Major Facilitator Superfamily
PMLHKFCF_01915 4.7e-241 amtB P ammonium transporter
PMLHKFCF_01916 2.3e-219 S Bacterial membrane protein YfhO
PMLHKFCF_01917 1.2e-225 nupG F Nucleoside
PMLHKFCF_01918 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PMLHKFCF_01919 7.9e-149 noc K Belongs to the ParB family
PMLHKFCF_01920 1.8e-136 soj D Sporulation initiation inhibitor
PMLHKFCF_01921 2.4e-156 spo0J K Belongs to the ParB family
PMLHKFCF_01922 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
PMLHKFCF_01923 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PMLHKFCF_01924 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
PMLHKFCF_01925 5.2e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PMLHKFCF_01926 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PMLHKFCF_01927 5.5e-124 yoaK S Protein of unknown function (DUF1275)
PMLHKFCF_01928 3.2e-124 K response regulator
PMLHKFCF_01929 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
PMLHKFCF_01930 2.1e-236 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PMLHKFCF_01931 3.2e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
PMLHKFCF_01932 5.1e-131 azlC E branched-chain amino acid
PMLHKFCF_01933 2.3e-54 azlD S branched-chain amino acid
PMLHKFCF_01934 5.2e-109 S membrane transporter protein
PMLHKFCF_01935 2.6e-30
PMLHKFCF_01937 2.3e-96 K Helix-turn-helix domain
PMLHKFCF_01938 2.5e-175 nsr 3.4.21.102 M Peptidase family S41
PMLHKFCF_01939 7.7e-18
PMLHKFCF_01940 2.8e-21 L Transposase
PMLHKFCF_01941 2.6e-79
PMLHKFCF_01942 5.3e-19
PMLHKFCF_01943 0.0 O Belongs to the peptidase S8 family
PMLHKFCF_01945 1e-78 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PMLHKFCF_01946 1e-174 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
PMLHKFCF_01947 2.6e-71 brnQ U Component of the transport system for branched-chain amino acids
PMLHKFCF_01948 0.0 lacS G Transporter
PMLHKFCF_01949 0.0 lacA 3.2.1.23 G -beta-galactosidase
PMLHKFCF_01950 1.7e-44 tnp2PF3 L Transposase DDE domain
PMLHKFCF_01951 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
PMLHKFCF_01952 2e-180 yvdE K helix_turn _helix lactose operon repressor
PMLHKFCF_01953 1e-190 malR K Transcriptional regulator, LacI family
PMLHKFCF_01954 7.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PMLHKFCF_01955 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
PMLHKFCF_01956 5.5e-101 dhaL 2.7.1.121 S Dak2
PMLHKFCF_01957 8e-185 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PMLHKFCF_01958 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PMLHKFCF_01959 1.9e-92 K Bacterial regulatory proteins, tetR family
PMLHKFCF_01961 9.5e-73 folT 2.7.13.3 T ECF transporter, substrate-specific component
PMLHKFCF_01962 1.8e-276 C Electron transfer flavoprotein FAD-binding domain
PMLHKFCF_01963 1.1e-116 K Transcriptional regulator
PMLHKFCF_01964 4.3e-297 M Exporter of polyketide antibiotics
PMLHKFCF_01965 2e-169 yjjC V ABC transporter
PMLHKFCF_01966 1.6e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
PMLHKFCF_01967 9.1e-89
PMLHKFCF_01968 5.8e-149
PMLHKFCF_01969 3e-134
PMLHKFCF_01970 8.3e-54 K Transcriptional regulator PadR-like family
PMLHKFCF_01971 1.6e-129 K UbiC transcription regulator-associated domain protein
PMLHKFCF_01973 2.5e-98 S UPF0397 protein
PMLHKFCF_01974 0.0 ykoD P ABC transporter, ATP-binding protein
PMLHKFCF_01975 4.9e-151 cbiQ P cobalt transport
PMLHKFCF_01976 4e-209 C Oxidoreductase
PMLHKFCF_01977 2.2e-258
PMLHKFCF_01978 7.8e-49
PMLHKFCF_01979 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
PMLHKFCF_01980 4.5e-82 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
PMLHKFCF_01981 1.2e-165 1.1.1.65 C Aldo keto reductase
PMLHKFCF_01982 3.4e-160 S reductase
PMLHKFCF_01984 8.1e-216 yeaN P Transporter, major facilitator family protein
PMLHKFCF_01985 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
PMLHKFCF_01986 4.7e-227 mdtG EGP Major facilitator Superfamily
PMLHKFCF_01987 5.8e-82 S Protein of unknown function (DUF3021)
PMLHKFCF_01988 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
PMLHKFCF_01989 1.2e-74 papX3 K Transcriptional regulator
PMLHKFCF_01990 3.6e-111 S NADPH-dependent FMN reductase
PMLHKFCF_01991 1.6e-28 KT PspC domain
PMLHKFCF_01992 2.9e-142 2.4.2.3 F Phosphorylase superfamily
PMLHKFCF_01993 0.0 pacL1 P P-type ATPase
PMLHKFCF_01994 3.3e-149 ydjP I Alpha/beta hydrolase family
PMLHKFCF_01995 5.2e-122
PMLHKFCF_01996 2.6e-250 yifK E Amino acid permease
PMLHKFCF_01997 3.4e-85 F NUDIX domain
PMLHKFCF_01998 9.8e-302 L HIRAN domain
PMLHKFCF_01999 4.3e-135 S peptidase C26
PMLHKFCF_02000 9.9e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
PMLHKFCF_02001 1.3e-111 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PMLHKFCF_02002 5.3e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PMLHKFCF_02003 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PMLHKFCF_02004 5.5e-178 1.6.5.5 C Zinc-binding dehydrogenase
PMLHKFCF_02005 6.3e-151 larE S NAD synthase
PMLHKFCF_02006 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PMLHKFCF_02007 8.5e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PMLHKFCF_02008 5.9e-124 larB S AIR carboxylase
PMLHKFCF_02009 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
PMLHKFCF_02010 2.1e-120 K Crp-like helix-turn-helix domain
PMLHKFCF_02011 4.8e-182 nikMN P PDGLE domain
PMLHKFCF_02012 2.6e-149 P Cobalt transport protein
PMLHKFCF_02013 7.8e-129 cbiO P ABC transporter
PMLHKFCF_02014 4.8e-40
PMLHKFCF_02015 2.3e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
PMLHKFCF_02017 7e-141
PMLHKFCF_02018 3.2e-308 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
PMLHKFCF_02019 6e-76
PMLHKFCF_02020 1.6e-140 S Belongs to the UPF0246 family
PMLHKFCF_02021 2.2e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
PMLHKFCF_02022 2.3e-235 mepA V MATE efflux family protein
PMLHKFCF_02023 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
PMLHKFCF_02024 5.4e-181 1.1.1.1 C nadph quinone reductase
PMLHKFCF_02025 2e-126 hchA S DJ-1/PfpI family
PMLHKFCF_02026 3.6e-93 MA20_25245 K FR47-like protein
PMLHKFCF_02027 8e-152 EG EamA-like transporter family
PMLHKFCF_02028 2.1e-61 S Protein of unknown function
PMLHKFCF_02029 8.2e-39 S Protein of unknown function
PMLHKFCF_02030 0.0 tetP J elongation factor G
PMLHKFCF_02031 1.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PMLHKFCF_02032 5.5e-172 yobV1 K WYL domain
PMLHKFCF_02033 3.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
PMLHKFCF_02034 2.9e-81 6.3.3.2 S ASCH
PMLHKFCF_02035 6.9e-254 1.14.14.9 Q 4-hydroxyphenylacetate
PMLHKFCF_02036 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
PMLHKFCF_02037 7.4e-250 yjjP S Putative threonine/serine exporter
PMLHKFCF_02038 6.7e-195 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PMLHKFCF_02039 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PMLHKFCF_02040 1.3e-290 QT PucR C-terminal helix-turn-helix domain
PMLHKFCF_02041 1.3e-122 drgA C Nitroreductase family
PMLHKFCF_02042 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
PMLHKFCF_02043 2.3e-164 ptlF S KR domain
PMLHKFCF_02044 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PMLHKFCF_02045 1e-72 C FMN binding
PMLHKFCF_02046 5.7e-158 K LysR family
PMLHKFCF_02047 1.3e-257 P Sodium:sulfate symporter transmembrane region
PMLHKFCF_02048 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
PMLHKFCF_02049 1.8e-116 S Elongation factor G-binding protein, N-terminal
PMLHKFCF_02050 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
PMLHKFCF_02051 5.7e-67 pnb C nitroreductase
PMLHKFCF_02052 4.2e-32 pnb C nitroreductase
PMLHKFCF_02053 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
PMLHKFCF_02054 7.2e-167 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PMLHKFCF_02055 1.7e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
PMLHKFCF_02056 1.5e-95 K Bacterial regulatory proteins, tetR family
PMLHKFCF_02057 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PMLHKFCF_02058 6.8e-173 htrA 3.4.21.107 O serine protease
PMLHKFCF_02059 8.9e-158 vicX 3.1.26.11 S domain protein
PMLHKFCF_02060 2.2e-151 yycI S YycH protein
PMLHKFCF_02061 1.2e-244 yycH S YycH protein
PMLHKFCF_02062 0.0 vicK 2.7.13.3 T Histidine kinase
PMLHKFCF_02063 6.2e-131 K response regulator
PMLHKFCF_02065 1.7e-37
PMLHKFCF_02066 1.6e-31 cspA K Cold shock protein domain
PMLHKFCF_02067 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
PMLHKFCF_02068 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
PMLHKFCF_02069 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PMLHKFCF_02070 4.5e-143 S haloacid dehalogenase-like hydrolase
PMLHKFCF_02071 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
PMLHKFCF_02072 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PMLHKFCF_02073 2e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
PMLHKFCF_02074 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
PMLHKFCF_02075 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PMLHKFCF_02076 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PMLHKFCF_02077 4.2e-276 E ABC transporter, substratebinding protein
PMLHKFCF_02079 1.2e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PMLHKFCF_02080 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PMLHKFCF_02081 8.8e-226 yttB EGP Major facilitator Superfamily
PMLHKFCF_02082 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PMLHKFCF_02083 1.4e-67 rplI J Binds to the 23S rRNA
PMLHKFCF_02084 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PMLHKFCF_02085 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PMLHKFCF_02086 1e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PMLHKFCF_02087 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
PMLHKFCF_02088 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PMLHKFCF_02089 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PMLHKFCF_02090 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PMLHKFCF_02091 5e-37 yaaA S S4 domain protein YaaA
PMLHKFCF_02092 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PMLHKFCF_02093 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PMLHKFCF_02094 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PMLHKFCF_02095 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PMLHKFCF_02096 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PMLHKFCF_02097 1e-309 E ABC transporter, substratebinding protein
PMLHKFCF_02098 1.3e-237 Q Imidazolonepropionase and related amidohydrolases
PMLHKFCF_02099 9.1e-109 jag S R3H domain protein
PMLHKFCF_02100 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PMLHKFCF_02101 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PMLHKFCF_02102 5.9e-92 S Cell surface protein
PMLHKFCF_02103 3e-158 S Bacterial protein of unknown function (DUF916)
PMLHKFCF_02105 1.1e-302
PMLHKFCF_02106 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PMLHKFCF_02108 1.5e-255 pepC 3.4.22.40 E aminopeptidase
PMLHKFCF_02109 8.4e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
PMLHKFCF_02110 2.8e-157 degV S DegV family
PMLHKFCF_02111 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
PMLHKFCF_02112 6.7e-142 tesE Q hydratase
PMLHKFCF_02113 4e-65 padC Q Phenolic acid decarboxylase
PMLHKFCF_02114 8.3e-17 S Protein of unknown function (DUF1093)
PMLHKFCF_02115 2.1e-20 3.4.21.19 M Belongs to the peptidase S1B family
PMLHKFCF_02116 6.2e-44 S Psort location CytoplasmicMembrane, score
PMLHKFCF_02118 0.0 pacL 3.6.3.8 P P-type ATPase
PMLHKFCF_02119 2.7e-42
PMLHKFCF_02120 2.8e-55 repA S Replication initiator protein A
PMLHKFCF_02121 1.6e-184 U Relaxase/Mobilisation nuclease domain
PMLHKFCF_02122 1.1e-54 S Bacterial mobilisation protein (MobC)
PMLHKFCF_02123 1.7e-36 K sequence-specific DNA binding
PMLHKFCF_02124 6.1e-45 S Phage derived protein Gp49-like (DUF891)
PMLHKFCF_02125 2.8e-105 L Integrase
PMLHKFCF_02126 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PMLHKFCF_02127 3.2e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
PMLHKFCF_02128 4.8e-62 S Protein of unknown function (DUF2992)
PMLHKFCF_02129 6.8e-10 K Helix-turn-helix XRE-family like proteins
PMLHKFCF_02130 1.2e-29
PMLHKFCF_02131 0.0 3.2.1.96 G Glycosyl hydrolase family 85
PMLHKFCF_02132 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PMLHKFCF_02133 4e-209 msmK P Belongs to the ABC transporter superfamily
PMLHKFCF_02134 5e-259 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
PMLHKFCF_02135 1.6e-149 malA S maltodextrose utilization protein MalA
PMLHKFCF_02136 1.4e-161 malD P ABC transporter permease
PMLHKFCF_02137 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
PMLHKFCF_02138 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
PMLHKFCF_02139 3.1e-63 L Belongs to the 'phage' integrase family
PMLHKFCF_02146 4.5e-78 K Peptidase S24-like
PMLHKFCF_02147 8.8e-20
PMLHKFCF_02150 7.2e-63 S DNA binding
PMLHKFCF_02157 6.3e-18
PMLHKFCF_02159 2.8e-146 S Protein of unknown function (DUF1351)
PMLHKFCF_02160 8.1e-117 S AAA domain
PMLHKFCF_02161 1.2e-91 S Protein of unknown function (DUF669)
PMLHKFCF_02162 3.9e-130 S Putative HNHc nuclease
PMLHKFCF_02163 1.3e-39 S calcium ion binding
PMLHKFCF_02164 1.4e-131 pi346 L IstB-like ATP binding protein
PMLHKFCF_02166 7.3e-86 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PMLHKFCF_02167 0.0 pepN 3.4.11.2 E aminopeptidase
PMLHKFCF_02168 1.1e-101 G Glycogen debranching enzyme
PMLHKFCF_02169 3.4e-10 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PMLHKFCF_02170 1.5e-154 yjdB S Domain of unknown function (DUF4767)
PMLHKFCF_02171 2.6e-149 Q Fumarylacetoacetate (FAA) hydrolase family
PMLHKFCF_02172 5.3e-72 asp2 S Asp23 family, cell envelope-related function
PMLHKFCF_02173 8.7e-72 asp S Asp23 family, cell envelope-related function
PMLHKFCF_02174 7.2e-23
PMLHKFCF_02175 4.4e-84
PMLHKFCF_02176 7.1e-37 S Transglycosylase associated protein
PMLHKFCF_02177 0.0 XK27_09800 I Acyltransferase family
PMLHKFCF_02178 1.1e-36 S MORN repeat
PMLHKFCF_02179 4.6e-25 S Cysteine-rich secretory protein family
PMLHKFCF_02181 1.4e-125 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PMLHKFCF_02182 0.0 L MobA MobL family protein
PMLHKFCF_02183 1.2e-26
PMLHKFCF_02184 2.6e-40
PMLHKFCF_02185 3.8e-40 S protein conserved in bacteria
PMLHKFCF_02186 5.5e-18
PMLHKFCF_02187 1.2e-123 repA S Replication initiator protein A
PMLHKFCF_02188 6.7e-246 cycA E Amino acid permease
PMLHKFCF_02190 5.4e-36 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PMLHKFCF_02191 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
PMLHKFCF_02192 1.2e-23 S Family of unknown function (DUF5388)
PMLHKFCF_02193 6.2e-96 V VanZ like family
PMLHKFCF_02194 5e-195 blaA6 V Beta-lactamase
PMLHKFCF_02195 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
PMLHKFCF_02196 1.9e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PMLHKFCF_02197 1.9e-52 yitW S Pfam:DUF59
PMLHKFCF_02198 1.7e-173 S Aldo keto reductase
PMLHKFCF_02199 3.3e-97 FG HIT domain
PMLHKFCF_02200 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
PMLHKFCF_02201 1.4e-77
PMLHKFCF_02202 2.4e-121 E GDSL-like Lipase/Acylhydrolase family
PMLHKFCF_02203 2.2e-126
PMLHKFCF_02204 1.1e-184 S DUF218 domain
PMLHKFCF_02205 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMLHKFCF_02206 1.2e-149 bla1 3.5.2.6 V Beta-lactamase enzyme family
PMLHKFCF_02207 3.9e-206 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PMLHKFCF_02208 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PMLHKFCF_02209 2.1e-31
PMLHKFCF_02210 1.7e-43 ankB S ankyrin repeats
PMLHKFCF_02211 6.5e-91 S ECF-type riboflavin transporter, S component
PMLHKFCF_02212 4.2e-47
PMLHKFCF_02213 9.8e-214 yceI EGP Major facilitator Superfamily
PMLHKFCF_02214 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
PMLHKFCF_02215 3.8e-23
PMLHKFCF_02217 4.1e-161 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_02218 8.2e-173 ykfC 3.4.14.13 M NlpC/P60 family
PMLHKFCF_02219 3.3e-80 K AsnC family
PMLHKFCF_02220 2e-35
PMLHKFCF_02221 3.3e-33
PMLHKFCF_02222 5.6e-217 2.7.7.65 T diguanylate cyclase
PMLHKFCF_02224 2.6e-169 EG EamA-like transporter family
PMLHKFCF_02225 2.3e-38 gcvR T Belongs to the UPF0237 family
PMLHKFCF_02226 3e-243 XK27_08635 S UPF0210 protein
PMLHKFCF_02227 1.6e-134 K response regulator
PMLHKFCF_02228 2.9e-287 yclK 2.7.13.3 T Histidine kinase
PMLHKFCF_02229 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
PMLHKFCF_02230 9.7e-155 glcU U sugar transport
PMLHKFCF_02231 2.8e-88
PMLHKFCF_02232 2.9e-176 L Initiator Replication protein
PMLHKFCF_02233 2.5e-29
PMLHKFCF_02234 2.3e-107 L Integrase
PMLHKFCF_02235 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
PMLHKFCF_02236 5.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
PMLHKFCF_02237 0.0 ybfG M peptidoglycan-binding domain-containing protein
PMLHKFCF_02239 8.5e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PMLHKFCF_02240 2.8e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PMLHKFCF_02241 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
PMLHKFCF_02242 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PMLHKFCF_02243 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PMLHKFCF_02244 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PMLHKFCF_02245 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
PMLHKFCF_02246 9.4e-297 S Alpha beta
PMLHKFCF_02247 1.8e-23
PMLHKFCF_02248 3e-99 S ECF transporter, substrate-specific component
PMLHKFCF_02249 5.8e-253 yfnA E Amino Acid
PMLHKFCF_02250 1.4e-165 mleP S Sodium Bile acid symporter family
PMLHKFCF_02251 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PMLHKFCF_02252 1.2e-166 mleR K LysR family
PMLHKFCF_02253 4.9e-162 mleR K LysR family transcriptional regulator
PMLHKFCF_02254 1e-93 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PMLHKFCF_02255 1.5e-261 frdC 1.3.5.4 C FAD binding domain
PMLHKFCF_02256 9.2e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PMLHKFCF_02257 3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
PMLHKFCF_02258 9.7e-161 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
PMLHKFCF_02259 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
PMLHKFCF_02260 1.7e-188 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PMLHKFCF_02261 3e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
PMLHKFCF_02262 2.9e-179 citR K sugar-binding domain protein
PMLHKFCF_02263 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
PMLHKFCF_02264 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PMLHKFCF_02265 3.1e-50
PMLHKFCF_02266 7.9e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
PMLHKFCF_02267 8.2e-141 mtsB U ABC 3 transport family
PMLHKFCF_02268 4.5e-132 mntB 3.6.3.35 P ABC transporter
PMLHKFCF_02269 1.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PMLHKFCF_02270 7.2e-197 K Helix-turn-helix domain
PMLHKFCF_02271 2.2e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
PMLHKFCF_02272 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
PMLHKFCF_02273 4.1e-53 yitW S Iron-sulfur cluster assembly protein
PMLHKFCF_02274 2.2e-221 P Sodium:sulfate symporter transmembrane region
PMLHKFCF_02276 1.8e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PMLHKFCF_02277 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
PMLHKFCF_02278 1.1e-164 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PMLHKFCF_02279 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PMLHKFCF_02280 1.5e-163 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PMLHKFCF_02281 5.5e-30 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PMLHKFCF_02282 2.2e-173 ywhK S Membrane
PMLHKFCF_02283 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
PMLHKFCF_02284 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PMLHKFCF_02285 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PMLHKFCF_02286 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PMLHKFCF_02287 6.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PMLHKFCF_02288 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PMLHKFCF_02289 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PMLHKFCF_02290 4.4e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PMLHKFCF_02291 3.5e-142 cad S FMN_bind
PMLHKFCF_02292 0.0 ndh 1.6.99.3 C NADH dehydrogenase
PMLHKFCF_02293 7.2e-86 ynhH S NusG domain II
PMLHKFCF_02294 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
PMLHKFCF_02295 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PMLHKFCF_02296 2.1e-61 rplQ J Ribosomal protein L17
PMLHKFCF_02297 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMLHKFCF_02298 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PMLHKFCF_02299 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PMLHKFCF_02300 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PMLHKFCF_02301 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PMLHKFCF_02302 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PMLHKFCF_02303 6.3e-70 rplO J Binds to the 23S rRNA
PMLHKFCF_02304 2.2e-24 rpmD J Ribosomal protein L30
PMLHKFCF_02305 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PMLHKFCF_02306 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PMLHKFCF_02307 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PMLHKFCF_02308 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PMLHKFCF_02309 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PMLHKFCF_02310 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PMLHKFCF_02311 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PMLHKFCF_02312 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PMLHKFCF_02313 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
PMLHKFCF_02314 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PMLHKFCF_02315 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PMLHKFCF_02316 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PMLHKFCF_02317 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PMLHKFCF_02318 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PMLHKFCF_02319 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PMLHKFCF_02320 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
PMLHKFCF_02321 1.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PMLHKFCF_02322 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PMLHKFCF_02323 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PMLHKFCF_02324 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PMLHKFCF_02325 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PMLHKFCF_02326 1.6e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PMLHKFCF_02327 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMLHKFCF_02328 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMLHKFCF_02329 1.5e-109 K Bacterial regulatory proteins, tetR family
PMLHKFCF_02330 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PMLHKFCF_02331 6.9e-78 ctsR K Belongs to the CtsR family
PMLHKFCF_02339 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PMLHKFCF_02340 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PMLHKFCF_02341 9.4e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PMLHKFCF_02342 1.6e-263 lysP E amino acid
PMLHKFCF_02343 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PMLHKFCF_02344 3.6e-91 K Transcriptional regulator
PMLHKFCF_02345 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
PMLHKFCF_02346 2e-154 I alpha/beta hydrolase fold
PMLHKFCF_02347 3.9e-119 lssY 3.6.1.27 I phosphatase
PMLHKFCF_02348 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PMLHKFCF_02349 2.2e-76 S Threonine/Serine exporter, ThrE
PMLHKFCF_02350 1.5e-130 thrE S Putative threonine/serine exporter
PMLHKFCF_02351 6e-31 cspC K Cold shock protein
PMLHKFCF_02352 2e-120 sirR K iron dependent repressor
PMLHKFCF_02353 2.6e-58
PMLHKFCF_02354 1.7e-84 merR K MerR HTH family regulatory protein
PMLHKFCF_02355 7e-270 lmrB EGP Major facilitator Superfamily
PMLHKFCF_02356 1.4e-117 S Domain of unknown function (DUF4811)
PMLHKFCF_02357 1e-106
PMLHKFCF_02358 4.4e-35 yyaN K MerR HTH family regulatory protein
PMLHKFCF_02359 1.7e-120 azlC E branched-chain amino acid
PMLHKFCF_02360 9.4e-50 azlD S Branched-chain amino acid transport protein (AzlD)
PMLHKFCF_02361 0.0 asnB 6.3.5.4 E Asparagine synthase
PMLHKFCF_02362 1e-218 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
PMLHKFCF_02363 1.5e-280 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PMLHKFCF_02364 1e-254 xylP2 G symporter
PMLHKFCF_02365 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
PMLHKFCF_02366 5.6e-49
PMLHKFCF_02367 3.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PMLHKFCF_02368 2e-91 3.2.2.20 K FR47-like protein
PMLHKFCF_02369 3.4e-127 yibF S overlaps another CDS with the same product name
PMLHKFCF_02370 1.4e-218 yibE S overlaps another CDS with the same product name
PMLHKFCF_02371 3.9e-179
PMLHKFCF_02372 5.6e-138 S NADPH-dependent FMN reductase
PMLHKFCF_02373 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
PMLHKFCF_02374 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PMLHKFCF_02375 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PMLHKFCF_02376 4.1e-32 L leucine-zipper of insertion element IS481
PMLHKFCF_02377 8.5e-41
PMLHKFCF_02378 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PMLHKFCF_02379 6.7e-278 pipD E Dipeptidase
PMLHKFCF_02380 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
PMLHKFCF_02381 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PMLHKFCF_02382 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PMLHKFCF_02383 2.3e-81 rmaD K Transcriptional regulator
PMLHKFCF_02385 1.3e-210 1.3.5.4 C FMN_bind
PMLHKFCF_02386 1.2e-97 1.3.5.4 C FMN_bind
PMLHKFCF_02387 2.8e-171 K Transcriptional regulator
PMLHKFCF_02388 5.2e-41 K Helix-turn-helix domain
PMLHKFCF_02389 7.2e-47 K Helix-turn-helix domain
PMLHKFCF_02390 2.3e-139 K sequence-specific DNA binding
PMLHKFCF_02391 6.5e-87 S AAA domain
PMLHKFCF_02393 2.6e-186 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
PMLHKFCF_02394 1e-298 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
PMLHKFCF_02395 5.5e-92 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
PMLHKFCF_02396 1.7e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
PMLHKFCF_02397 2.7e-171 L Belongs to the 'phage' integrase family
PMLHKFCF_02398 1.6e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PMLHKFCF_02399 1.7e-151 hsdM 2.1.1.72 V type I restriction-modification system
PMLHKFCF_02400 3.7e-95 hsdM 2.1.1.72 V type I restriction-modification system
PMLHKFCF_02401 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PMLHKFCF_02402 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PMLHKFCF_02403 1.5e-65
PMLHKFCF_02404 1.3e-117
PMLHKFCF_02405 0.0 L MobA MobL family protein
PMLHKFCF_02406 7.9e-26
PMLHKFCF_02407 1.2e-40
PMLHKFCF_02408 5.7e-86
PMLHKFCF_02409 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
PMLHKFCF_02410 9e-14 Q Methyltransferase
PMLHKFCF_02411 6.2e-32
PMLHKFCF_02412 3e-25
PMLHKFCF_02413 0.0 traA L MobA MobL family protein
PMLHKFCF_02414 3.2e-256 ykgC 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMLHKFCF_02415 1.5e-67 M Cna protein B-type domain
PMLHKFCF_02416 3.2e-109 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMLHKFCF_02417 2e-132 S Cysteine-rich secretory protein family
PMLHKFCF_02418 6.7e-232 EGP Major facilitator Superfamily
PMLHKFCF_02419 1.7e-159 L hmm pf00665
PMLHKFCF_02420 1.5e-129 L Helix-turn-helix domain
PMLHKFCF_02421 1.1e-56 hxlR K HxlR-like helix-turn-helix
PMLHKFCF_02422 7.6e-110 XK27_07075 V CAAX protease self-immunity
PMLHKFCF_02423 1.2e-82 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PMLHKFCF_02424 2.8e-239 P Sodium:sulfate symporter transmembrane region
PMLHKFCF_02425 2.4e-301 1.3.5.4 C FMN_bind
PMLHKFCF_02426 5.4e-132 K LysR family
PMLHKFCF_02427 7.9e-60 mleR K LysR substrate binding domain
PMLHKFCF_02429 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PMLHKFCF_02430 2.7e-79 T Universal stress protein family
PMLHKFCF_02431 2.2e-99 padR K Virulence activator alpha C-term
PMLHKFCF_02432 9.2e-28 padC Q Phenolic acid decarboxylase
PMLHKFCF_02433 1.5e-42 S COG NOG38524 non supervised orthologous group
PMLHKFCF_02436 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
PMLHKFCF_02437 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
PMLHKFCF_02438 2.3e-107 L Integrase
PMLHKFCF_02439 4.9e-16
PMLHKFCF_02440 5.4e-64 tcmJ G COG0662 Mannose-6-phosphate isomerase
PMLHKFCF_02441 6.4e-46 M domain protein
PMLHKFCF_02442 6e-52 ykoF S YKOF-related Family
PMLHKFCF_02443 3.3e-11 glnA 6.3.1.2 E glutamine synthetase
PMLHKFCF_02444 1.5e-193 glnA 6.3.1.2 E glutamine synthetase
PMLHKFCF_02445 0.0 rafA 3.2.1.22 G alpha-galactosidase
PMLHKFCF_02446 9.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
PMLHKFCF_02447 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PMLHKFCF_02449 2.9e-38 sirR K Helix-turn-helix diphteria tox regulatory element
PMLHKFCF_02450 1.5e-249 mntH P H( )-stimulated, divalent metal cation uptake system
PMLHKFCF_02451 6.2e-57 T Belongs to the universal stress protein A family
PMLHKFCF_02452 1e-96 tnpR1 L Resolvase, N terminal domain
PMLHKFCF_02453 7.5e-49 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_02454 1.2e-14 K Bacterial regulatory proteins, tetR family
PMLHKFCF_02455 4.7e-214 S membrane
PMLHKFCF_02456 9.2e-82 K Bacterial regulatory proteins, tetR family
PMLHKFCF_02457 0.0 CP_1020 S Zinc finger, swim domain protein
PMLHKFCF_02458 4.1e-68 S Protein of unknown function (DUF1722)
PMLHKFCF_02459 9.1e-71 yneH 1.20.4.1 P ArsC family
PMLHKFCF_02460 1.2e-106 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
PMLHKFCF_02461 8e-137 K DeoR C terminal sensor domain
PMLHKFCF_02462 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PMLHKFCF_02463 9.2e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PMLHKFCF_02464 4.3e-77 K Transcriptional regulator
PMLHKFCF_02465 2.2e-241 EGP Major facilitator Superfamily
PMLHKFCF_02466 2.6e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PMLHKFCF_02467 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
PMLHKFCF_02468 2.2e-179 C Zinc-binding dehydrogenase
PMLHKFCF_02469 7e-214 I transferase activity, transferring acyl groups other than amino-acyl groups
PMLHKFCF_02470 1.7e-207
PMLHKFCF_02471 8.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
PMLHKFCF_02472 7.8e-61 P Rhodanese Homology Domain
PMLHKFCF_02473 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PMLHKFCF_02474 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
PMLHKFCF_02475 3.2e-167 drrA V ABC transporter
PMLHKFCF_02476 2e-119 drrB U ABC-2 type transporter
PMLHKFCF_02477 6.9e-223 M O-Antigen ligase
PMLHKFCF_02478 5.6e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
PMLHKFCF_02479 7.2e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PMLHKFCF_02480 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PMLHKFCF_02481 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PMLHKFCF_02483 5.6e-29 S Protein of unknown function (DUF2929)
PMLHKFCF_02484 0.0 dnaE 2.7.7.7 L DNA polymerase
PMLHKFCF_02485 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PMLHKFCF_02486 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PMLHKFCF_02487 1.5e-74 yeaL S Protein of unknown function (DUF441)
PMLHKFCF_02488 1.1e-169 cvfB S S1 domain
PMLHKFCF_02489 1.1e-164 xerD D recombinase XerD
PMLHKFCF_02490 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PMLHKFCF_02491 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PMLHKFCF_02492 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PMLHKFCF_02493 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PMLHKFCF_02494 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PMLHKFCF_02495 3.6e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
PMLHKFCF_02496 6.2e-271 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
PMLHKFCF_02497 2e-19 M Lysin motif
PMLHKFCF_02498 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PMLHKFCF_02499 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
PMLHKFCF_02500 1e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PMLHKFCF_02501 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PMLHKFCF_02502 2.1e-206 S Tetratricopeptide repeat protein
PMLHKFCF_02503 3.3e-149 3.1.3.102, 3.1.3.104 S hydrolase
PMLHKFCF_02504 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PMLHKFCF_02505 2.1e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PMLHKFCF_02506 9.6e-85
PMLHKFCF_02507 0.0 yfmR S ABC transporter, ATP-binding protein
PMLHKFCF_02508 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PMLHKFCF_02509 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PMLHKFCF_02510 5.1e-148 DegV S EDD domain protein, DegV family
PMLHKFCF_02511 2.1e-150 ypmR E GDSL-like Lipase/Acylhydrolase
PMLHKFCF_02512 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PMLHKFCF_02513 3.4e-35 yozE S Belongs to the UPF0346 family
PMLHKFCF_02514 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
PMLHKFCF_02515 7.3e-251 emrY EGP Major facilitator Superfamily
PMLHKFCF_02516 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
PMLHKFCF_02517 4.2e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PMLHKFCF_02518 2.3e-173 L restriction endonuclease
PMLHKFCF_02519 3.1e-170 cpsY K Transcriptional regulator, LysR family
PMLHKFCF_02520 6.8e-228 XK27_05470 E Methionine synthase
PMLHKFCF_02522 4.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PMLHKFCF_02523 8.2e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PMLHKFCF_02524 9.5e-158 dprA LU DNA protecting protein DprA
PMLHKFCF_02525 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PMLHKFCF_02526 6.6e-251 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PMLHKFCF_02527 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
PMLHKFCF_02528 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PMLHKFCF_02529 8.6e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PMLHKFCF_02530 3.8e-170 lacX 5.1.3.3 G Aldose 1-epimerase
PMLHKFCF_02531 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PMLHKFCF_02532 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PMLHKFCF_02533 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PMLHKFCF_02534 5.9e-177 K Transcriptional regulator
PMLHKFCF_02535 2.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
PMLHKFCF_02536 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PMLHKFCF_02537 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMLHKFCF_02538 4.2e-32 S YozE SAM-like fold
PMLHKFCF_02539 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain
PMLHKFCF_02540 3e-276 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PMLHKFCF_02541 6.3e-246 M Glycosyl transferase family group 2
PMLHKFCF_02542 1.8e-66
PMLHKFCF_02543 9.3e-253 gshR1 1.8.1.7 C Glutathione reductase
PMLHKFCF_02544 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
PMLHKFCF_02545 5.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PMLHKFCF_02546 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PMLHKFCF_02547 9.9e-216 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PMLHKFCF_02548 9.7e-194 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
PMLHKFCF_02549 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
PMLHKFCF_02550 5.1e-227
PMLHKFCF_02551 4.6e-275 lldP C L-lactate permease
PMLHKFCF_02552 4.1e-59
PMLHKFCF_02553 3.5e-123
PMLHKFCF_02554 7.6e-222 cycA E Amino acid permease
PMLHKFCF_02555 3.7e-130 XK27_00890 S Domain of unknown function (DUF368)
PMLHKFCF_02556 4.6e-129 yejC S Protein of unknown function (DUF1003)
PMLHKFCF_02557 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
PMLHKFCF_02558 4.6e-12
PMLHKFCF_02559 1.6e-211 pmrB EGP Major facilitator Superfamily
PMLHKFCF_02560 3.3e-149 2.7.7.12 C Domain of unknown function (DUF4931)
PMLHKFCF_02561 1.4e-49
PMLHKFCF_02562 1.6e-09
PMLHKFCF_02563 2.9e-131 S Protein of unknown function (DUF975)
PMLHKFCF_02564 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
PMLHKFCF_02565 2.1e-160 degV S EDD domain protein, DegV family
PMLHKFCF_02566 1.9e-66 K Transcriptional regulator
PMLHKFCF_02567 0.0 FbpA K Fibronectin-binding protein
PMLHKFCF_02568 9.3e-133 S ABC-2 family transporter protein
PMLHKFCF_02569 5.4e-164 V ABC transporter, ATP-binding protein
PMLHKFCF_02570 3e-92 3.6.1.55 F NUDIX domain
PMLHKFCF_02571 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
PMLHKFCF_02572 1.2e-69 S LuxR family transcriptional regulator
PMLHKFCF_02573 1.7e-130 cat 2.3.1.28 V Chloramphenicol acetyltransferase
PMLHKFCF_02576 3.1e-71 frataxin S Domain of unknown function (DU1801)
PMLHKFCF_02577 5.5e-112 pgm5 G Phosphoglycerate mutase family
PMLHKFCF_02578 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PMLHKFCF_02579 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
PMLHKFCF_02580 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PMLHKFCF_02581 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PMLHKFCF_02582 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PMLHKFCF_02583 1.1e-292 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PMLHKFCF_02584 2.2e-61 esbA S Family of unknown function (DUF5322)
PMLHKFCF_02585 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
PMLHKFCF_02586 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
PMLHKFCF_02587 5.9e-146 S hydrolase activity, acting on ester bonds
PMLHKFCF_02588 2.3e-193
PMLHKFCF_02589 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
PMLHKFCF_02590 1.3e-123
PMLHKFCF_02591 2.3e-181 mccF 3.4.17.13 V LD-carboxypeptidase
PMLHKFCF_02592 2.6e-239 M hydrolase, family 25
PMLHKFCF_02593 1.2e-198 aspT U Predicted Permease Membrane Region
PMLHKFCF_02594 4.5e-238 asdA 4.1.1.12 E Aminotransferase class I and II
PMLHKFCF_02595 1.5e-65 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMLHKFCF_02597 4.7e-25
PMLHKFCF_02598 0.0 mco Q Multicopper oxidase
PMLHKFCF_02599 3e-238 EGP Major Facilitator Superfamily
PMLHKFCF_02600 1.9e-54
PMLHKFCF_02601 7.4e-57 L Transposase IS66 family
PMLHKFCF_02602 1.5e-194 pbuX F xanthine permease
PMLHKFCF_02603 3.7e-24
PMLHKFCF_02604 1.9e-56 XK27_01125 L PFAM IS66 Orf2 family protein
PMLHKFCF_02605 8e-18
PMLHKFCF_02608 5.2e-34
PMLHKFCF_02609 4.2e-144 soj D AAA domain
PMLHKFCF_02610 7.6e-55 K helix_turn_helix multiple antibiotic resistance protein
PMLHKFCF_02611 0.0 kup P Transport of potassium into the cell
PMLHKFCF_02612 4.9e-38 KT Transcriptional regulatory protein, C terminal
PMLHKFCF_02613 4.2e-113 papP P ABC transporter, permease protein
PMLHKFCF_02614 4.3e-113 P ABC transporter permease
PMLHKFCF_02615 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMLHKFCF_02616 9.1e-153 cjaA ET ABC transporter substrate-binding protein
PMLHKFCF_02617 3.5e-45 tnp2PF3 L Transposase DDE domain
PMLHKFCF_02618 6.6e-28 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PMLHKFCF_02619 1.7e-18
PMLHKFCF_02620 2e-184 L Psort location Cytoplasmic, score
PMLHKFCF_02621 8e-68 C lyase activity
PMLHKFCF_02624 3.8e-98 soj D CobQ CobB MinD ParA nucleotide binding domain protein
PMLHKFCF_02625 2.1e-11
PMLHKFCF_02626 1.6e-100 S Protein of unknown function (DUF1211)
PMLHKFCF_02627 1.2e-191 1.1.1.219 GM Male sterility protein
PMLHKFCF_02628 4.8e-94 K Bacterial regulatory proteins, tetR family
PMLHKFCF_02629 7.6e-64 L Transposase
PMLHKFCF_02630 1.1e-130 S Phage Mu protein F like protein
PMLHKFCF_02631 1.2e-12 ytgB S Transglycosylase associated protein
PMLHKFCF_02632 1.6e-75 yugI 5.3.1.9 J general stress protein
PMLHKFCF_02633 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PMLHKFCF_02634 1.9e-118 dedA S SNARE-like domain protein
PMLHKFCF_02635 1.8e-116 S Protein of unknown function (DUF1461)
PMLHKFCF_02636 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PMLHKFCF_02637 1.5e-80 yutD S Protein of unknown function (DUF1027)
PMLHKFCF_02638 1.5e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PMLHKFCF_02639 4.4e-117 S Calcineurin-like phosphoesterase
PMLHKFCF_02640 5.3e-251 cycA E Amino acid permease
PMLHKFCF_02641 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMLHKFCF_02642 4e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
PMLHKFCF_02644 4.5e-88 S Prokaryotic N-terminal methylation motif
PMLHKFCF_02645 8.6e-20
PMLHKFCF_02646 3.2e-83 gspG NU general secretion pathway protein
PMLHKFCF_02647 5.5e-43 comGC U competence protein ComGC
PMLHKFCF_02648 1.9e-189 comGB NU type II secretion system
PMLHKFCF_02649 2.1e-174 comGA NU Type II IV secretion system protein
PMLHKFCF_02650 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMLHKFCF_02651 8.3e-131 yebC K Transcriptional regulatory protein
PMLHKFCF_02652 1.6e-49 S DsrE/DsrF-like family
PMLHKFCF_02653 6.8e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
PMLHKFCF_02654 1.9e-181 ccpA K catabolite control protein A
PMLHKFCF_02655 2.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PMLHKFCF_02656 1.9e-62 K helix_turn_helix, mercury resistance
PMLHKFCF_02657 2.8e-56
PMLHKFCF_02658 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PMLHKFCF_02659 2.6e-158 ykuT M mechanosensitive ion channel
PMLHKFCF_02660 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PMLHKFCF_02661 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PMLHKFCF_02662 6.5e-87 ykuL S (CBS) domain
PMLHKFCF_02663 9.5e-97 S Phosphoesterase
PMLHKFCF_02664 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PMLHKFCF_02665 9e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PMLHKFCF_02666 7.6e-126 yslB S Protein of unknown function (DUF2507)
PMLHKFCF_02667 3.3e-52 trxA O Belongs to the thioredoxin family
PMLHKFCF_02668 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PMLHKFCF_02669 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PMLHKFCF_02670 1.6e-48 yrzB S Belongs to the UPF0473 family
PMLHKFCF_02671 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PMLHKFCF_02672 2.4e-43 yrzL S Belongs to the UPF0297 family
PMLHKFCF_02673 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PMLHKFCF_02674 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PMLHKFCF_02675 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PMLHKFCF_02676 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PMLHKFCF_02677 2.8e-29 yajC U Preprotein translocase
PMLHKFCF_02678 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PMLHKFCF_02679 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PMLHKFCF_02680 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PMLHKFCF_02681 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PMLHKFCF_02682 9.6e-89
PMLHKFCF_02683 0.0 S Bacterial membrane protein YfhO
PMLHKFCF_02684 3.1e-71
PMLHKFCF_02685 0.0 L Transposase
PMLHKFCF_02686 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PMLHKFCF_02687 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PMLHKFCF_02688 2.7e-154 ymdB S YmdB-like protein
PMLHKFCF_02689 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
PMLHKFCF_02690 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PMLHKFCF_02691 2.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
PMLHKFCF_02692 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PMLHKFCF_02693 5.7e-110 ymfM S Helix-turn-helix domain
PMLHKFCF_02694 2.9e-251 ymfH S Peptidase M16
PMLHKFCF_02695 1.9e-231 ymfF S Peptidase M16 inactive domain protein
PMLHKFCF_02696 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
PMLHKFCF_02697 1.5e-155 aatB ET ABC transporter substrate-binding protein
PMLHKFCF_02698 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMLHKFCF_02699 4.6e-109 glnP P ABC transporter permease
PMLHKFCF_02700 1.2e-146 minD D Belongs to the ParA family
PMLHKFCF_02701 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PMLHKFCF_02702 1.2e-88 mreD M rod shape-determining protein MreD
PMLHKFCF_02703 2.6e-144 mreC M Involved in formation and maintenance of cell shape
PMLHKFCF_02704 2.8e-161 mreB D cell shape determining protein MreB
PMLHKFCF_02705 1.3e-116 radC L DNA repair protein
PMLHKFCF_02706 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PMLHKFCF_02707 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PMLHKFCF_02708 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PMLHKFCF_02709 1.2e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PMLHKFCF_02710 1.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PMLHKFCF_02711 8.3e-218 iscS2 2.8.1.7 E Aminotransferase class V
PMLHKFCF_02712 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PMLHKFCF_02713 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
PMLHKFCF_02714 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PMLHKFCF_02715 5.2e-113 yktB S Belongs to the UPF0637 family
PMLHKFCF_02716 7.3e-80 yueI S Protein of unknown function (DUF1694)
PMLHKFCF_02717 2.2e-108 S Protein of unknown function (DUF1648)
PMLHKFCF_02718 1.9e-43 czrA K Helix-turn-helix domain
PMLHKFCF_02719 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PMLHKFCF_02720 8e-238 rarA L recombination factor protein RarA
PMLHKFCF_02721 1.5e-38
PMLHKFCF_02722 6.2e-82 usp6 T universal stress protein
PMLHKFCF_02723 6.3e-202 bla2 3.5.2.6 V Beta-lactamase enzyme family
PMLHKFCF_02724 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
PMLHKFCF_02725 7.1e-297 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
PMLHKFCF_02726 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PMLHKFCF_02727 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PMLHKFCF_02728 1.6e-177 S Protein of unknown function (DUF2785)
PMLHKFCF_02729 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
PMLHKFCF_02730 6.5e-148 metQ M Belongs to the nlpA lipoprotein family
PMLHKFCF_02731 1.4e-111 metI U ABC transporter permease
PMLHKFCF_02732 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PMLHKFCF_02733 3.6e-48 gcsH2 E glycine cleavage
PMLHKFCF_02734 9.3e-220 rodA D Belongs to the SEDS family
PMLHKFCF_02735 1.2e-32 S Protein of unknown function (DUF2969)
PMLHKFCF_02736 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PMLHKFCF_02737 2.7e-180 mbl D Cell shape determining protein MreB Mrl
PMLHKFCF_02738 2.1e-102 J Acetyltransferase (GNAT) domain
PMLHKFCF_02739 3.7e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PMLHKFCF_02740 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PMLHKFCF_02741 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PMLHKFCF_02742 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PMLHKFCF_02743 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PMLHKFCF_02744 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PMLHKFCF_02745 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PMLHKFCF_02746 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PMLHKFCF_02747 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
PMLHKFCF_02748 3e-232 pyrP F Permease
PMLHKFCF_02750 1.6e-39 L Transposase
PMLHKFCF_02751 8.8e-95 L 4.5 Transposon and IS
PMLHKFCF_02753 1.5e-15 S Alpha/beta hydrolase of unknown function (DUF915)
PMLHKFCF_02754 4.7e-28 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMLHKFCF_02755 6.6e-136 L Replication protein
PMLHKFCF_02756 4e-151 glcU U sugar transport
PMLHKFCF_02757 4.2e-150 S Uncharacterised protein, DegV family COG1307
PMLHKFCF_02758 1.8e-85 2.5.1.74 H UbiA prenyltransferase family
PMLHKFCF_02759 3.7e-31 tnp2PF3 L manually curated
PMLHKFCF_02760 3.8e-40
PMLHKFCF_02761 6e-31 cspA K Cold shock protein
PMLHKFCF_02762 7e-57
PMLHKFCF_02763 1.2e-163 L PFAM Integrase catalytic region
PMLHKFCF_02764 1.7e-88 L Helix-turn-helix domain
PMLHKFCF_02765 1.4e-34 lytE M LysM domain protein
PMLHKFCF_02766 9.8e-34 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
PMLHKFCF_02767 3.1e-36 L Resolvase, N terminal domain
PMLHKFCF_02769 3.7e-111 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
PMLHKFCF_02770 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
PMLHKFCF_02771 1.3e-128 K Helix-turn-helix domain, rpiR family
PMLHKFCF_02772 8.5e-159 S Alpha beta hydrolase
PMLHKFCF_02773 9.9e-112 GM NmrA-like family
PMLHKFCF_02774 4.9e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
PMLHKFCF_02775 1.9e-161 K Transcriptional regulator
PMLHKFCF_02776 1.9e-172 C nadph quinone reductase
PMLHKFCF_02777 6.3e-14 S Alpha beta hydrolase
PMLHKFCF_02778 6.9e-217 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PMLHKFCF_02779 4e-102 desR K helix_turn_helix, Lux Regulon
PMLHKFCF_02780 2.8e-207 desK 2.7.13.3 T Histidine kinase
PMLHKFCF_02781 3.1e-136 yvfS V ABC-2 type transporter
PMLHKFCF_02782 5.2e-159 yvfR V ABC transporter
PMLHKFCF_02784 6e-82 K Acetyltransferase (GNAT) domain
PMLHKFCF_02785 2.4e-72 K MarR family
PMLHKFCF_02786 3.8e-114 S Psort location CytoplasmicMembrane, score
PMLHKFCF_02787 2.6e-12 yjdF S Protein of unknown function (DUF2992)
PMLHKFCF_02788 5.6e-161 V ABC transporter, ATP-binding protein
PMLHKFCF_02789 5.2e-128 S ABC-2 family transporter protein
PMLHKFCF_02790 1.5e-197
PMLHKFCF_02791 5.9e-202
PMLHKFCF_02792 4.8e-165 ytrB V ABC transporter, ATP-binding protein
PMLHKFCF_02793 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
PMLHKFCF_02794 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PMLHKFCF_02795 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PMLHKFCF_02796 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PMLHKFCF_02797 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PMLHKFCF_02798 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
PMLHKFCF_02799 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PMLHKFCF_02800 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PMLHKFCF_02801 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PMLHKFCF_02802 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
PMLHKFCF_02803 2.6e-71 yqeY S YqeY-like protein
PMLHKFCF_02804 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PMLHKFCF_02805 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PMLHKFCF_02806 7.7e-109 C Enoyl-(Acyl carrier protein) reductase
PMLHKFCF_02807 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PMLHKFCF_02808 6.6e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PMLHKFCF_02809 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PMLHKFCF_02810 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMLHKFCF_02811 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PMLHKFCF_02812 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
PMLHKFCF_02813 4.3e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PMLHKFCF_02814 1.6e-160 yniA G Fructosamine kinase
PMLHKFCF_02815 6.5e-116 3.1.3.18 J HAD-hyrolase-like
PMLHKFCF_02816 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PMLHKFCF_02817 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMLHKFCF_02818 9.6e-58
PMLHKFCF_02819 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PMLHKFCF_02820 9e-12 prmA J Ribosomal protein L11 methyltransferase
PMLHKFCF_02821 2.6e-155 prmA J Ribosomal protein L11 methyltransferase
PMLHKFCF_02822 4e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PMLHKFCF_02823 1.4e-49
PMLHKFCF_02824 1.4e-49
PMLHKFCF_02827 4e-127 3.6.4.12 L Belongs to the 'phage' integrase family
PMLHKFCF_02828 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PMLHKFCF_02829 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PMLHKFCF_02830 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PMLHKFCF_02831 2.5e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
PMLHKFCF_02832 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PMLHKFCF_02833 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
PMLHKFCF_02834 4.4e-198 pbpX2 V Beta-lactamase
PMLHKFCF_02835 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PMLHKFCF_02836 0.0 dnaK O Heat shock 70 kDa protein
PMLHKFCF_02837 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PMLHKFCF_02838 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PMLHKFCF_02839 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
PMLHKFCF_02840 1.7e-187 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PMLHKFCF_02841 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PMLHKFCF_02842 2e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PMLHKFCF_02843 5.5e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PMLHKFCF_02844 2.5e-223 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PMLHKFCF_02845 8.5e-93
PMLHKFCF_02846 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PMLHKFCF_02847 2e-264 ydiN 5.4.99.5 G Major Facilitator
PMLHKFCF_02848 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PMLHKFCF_02849 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PMLHKFCF_02850 3.1e-47 ylxQ J ribosomal protein
PMLHKFCF_02851 9.5e-49 ylxR K Protein of unknown function (DUF448)
PMLHKFCF_02852 3.3e-217 nusA K Participates in both transcription termination and antitermination
PMLHKFCF_02853 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
PMLHKFCF_02854 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PMLHKFCF_02855 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PMLHKFCF_02856 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PMLHKFCF_02857 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
PMLHKFCF_02858 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PMLHKFCF_02859 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PMLHKFCF_02860 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PMLHKFCF_02861 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PMLHKFCF_02862 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
PMLHKFCF_02863 4.7e-134 S Haloacid dehalogenase-like hydrolase
PMLHKFCF_02864 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMLHKFCF_02865 7e-39 yazA L GIY-YIG catalytic domain protein
PMLHKFCF_02866 2.1e-132 yabB 2.1.1.223 L Methyltransferase small domain
PMLHKFCF_02867 6.4e-119 plsC 2.3.1.51 I Acyltransferase
PMLHKFCF_02868 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
PMLHKFCF_02869 2.9e-36 ynzC S UPF0291 protein
PMLHKFCF_02870 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PMLHKFCF_02871 3.7e-87
PMLHKFCF_02872 1.8e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PMLHKFCF_02873 4.6e-75
PMLHKFCF_02874 3e-66
PMLHKFCF_02875 1.5e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
PMLHKFCF_02876 9.2e-101 L Helix-turn-helix domain
PMLHKFCF_02877 2.4e-220 lytR5 K Cell envelope-related transcriptional attenuator domain
PMLHKFCF_02878 7.9e-143 P ATPases associated with a variety of cellular activities
PMLHKFCF_02879 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
PMLHKFCF_02880 2.2e-229 rodA D Cell cycle protein
PMLHKFCF_02882 4.4e-127 terC P integral membrane protein, YkoY family
PMLHKFCF_02883 4.8e-58
PMLHKFCF_02884 4.2e-70 S Pyrimidine dimer DNA glycosylase
PMLHKFCF_02885 3e-116 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PMLHKFCF_02887 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PMLHKFCF_02888 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PMLHKFCF_02889 2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PMLHKFCF_02890 3.9e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PMLHKFCF_02891 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PMLHKFCF_02892 9.3e-109 tdk 2.7.1.21 F thymidine kinase
PMLHKFCF_02893 6.5e-136 cobQ S glutamine amidotransferase
PMLHKFCF_02894 2.8e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
PMLHKFCF_02895 1.2e-191 ampC V Beta-lactamase
PMLHKFCF_02896 5.2e-29
PMLHKFCF_02897 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PMLHKFCF_02898 1.9e-58
PMLHKFCF_02899 2.8e-126
PMLHKFCF_02900 0.0 yfiC V ABC transporter
PMLHKFCF_02901 2.2e-310 ycfI V ABC transporter, ATP-binding protein
PMLHKFCF_02902 3.3e-65 S Protein of unknown function (DUF1093)
PMLHKFCF_02903 1.3e-132 yxkH G Polysaccharide deacetylase
PMLHKFCF_02905 3.3e-61 V Abortive infection bacteriophage resistance protein
PMLHKFCF_02906 2.7e-27 hol S Bacteriophage holin
PMLHKFCF_02907 2.4e-35 S Haemolysin XhlA
PMLHKFCF_02908 2.2e-200 lys M Glycosyl hydrolases family 25
PMLHKFCF_02910 5.9e-21
PMLHKFCF_02911 1e-87
PMLHKFCF_02914 2.6e-15 S Domain of unknown function (DUF2479)
PMLHKFCF_02915 3.3e-96 S Domain of unknown function (DUF2479)
PMLHKFCF_02916 1.2e-172 E GDSL-like Lipase/Acylhydrolase family
PMLHKFCF_02917 1e-289 M Prophage endopeptidase tail
PMLHKFCF_02918 8.1e-134 S phage tail
PMLHKFCF_02919 0.0 D NLP P60 protein
PMLHKFCF_02921 4.3e-83 S Phage tail assembly chaperone protein, TAC
PMLHKFCF_02922 6.7e-96
PMLHKFCF_02923 4.1e-61
PMLHKFCF_02924 3.6e-94
PMLHKFCF_02925 1.7e-50
PMLHKFCF_02926 1.5e-56 S Phage gp6-like head-tail connector protein
PMLHKFCF_02927 1.5e-194 gpG
PMLHKFCF_02928 8.6e-71 S Domain of unknown function (DUF4355)
PMLHKFCF_02929 2.9e-168 S Phage Mu protein F like protein
PMLHKFCF_02930 7.6e-305 S Phage portal protein, SPP1 Gp6-like
PMLHKFCF_02931 8.7e-248 S Phage terminase, large subunit
PMLHKFCF_02933 2e-75 ps333 L Terminase small subunit
PMLHKFCF_02934 3.5e-11
PMLHKFCF_02936 2.2e-17
PMLHKFCF_02937 6.6e-31 rplV S ASCH
PMLHKFCF_02938 1.3e-79 K acetyltransferase
PMLHKFCF_02942 4.1e-14
PMLHKFCF_02943 2.4e-13 S YopX protein
PMLHKFCF_02945 1.2e-64 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
PMLHKFCF_02946 8.4e-85
PMLHKFCF_02947 2.2e-50
PMLHKFCF_02948 2.5e-161 L DnaD domain protein
PMLHKFCF_02949 1.4e-64
PMLHKFCF_02950 1.6e-54 S Bacteriophage Mu Gam like protein
PMLHKFCF_02952 2.8e-85
PMLHKFCF_02953 4.5e-54
PMLHKFCF_02955 1.3e-37 K Helix-turn-helix
PMLHKFCF_02956 4.5e-61 yvaO K Helix-turn-helix domain
PMLHKFCF_02957 3.3e-76 E IrrE N-terminal-like domain
PMLHKFCF_02958 8.4e-37
PMLHKFCF_02960 4.1e-13 S DNA/RNA non-specific endonuclease
PMLHKFCF_02964 7.3e-219 int L Belongs to the 'phage' integrase family
PMLHKFCF_02966 8.9e-30
PMLHKFCF_02969 3.6e-61
PMLHKFCF_02970 1.1e-35 S Phage gp6-like head-tail connector protein
PMLHKFCF_02971 7.2e-278 S Caudovirus prohead serine protease
PMLHKFCF_02972 1.1e-203 S Phage portal protein
PMLHKFCF_02974 0.0 terL S overlaps another CDS with the same product name
PMLHKFCF_02975 2.5e-83 terS L Phage terminase, small subunit
PMLHKFCF_02976 1.6e-67 L Phage-associated protein
PMLHKFCF_02977 4.6e-47 S head-tail joining protein
PMLHKFCF_02979 7e-74
PMLHKFCF_02980 7.9e-263 S Virulence-associated protein E
PMLHKFCF_02981 4.1e-147 L DNA replication protein
PMLHKFCF_02982 1.6e-29
PMLHKFCF_02986 6.4e-226 sip L Belongs to the 'phage' integrase family
PMLHKFCF_02987 2e-38
PMLHKFCF_02988 1.4e-43
PMLHKFCF_02989 7.3e-83 K MarR family
PMLHKFCF_02990 0.0 bztC D nuclear chromosome segregation
PMLHKFCF_02991 2.6e-113 M MucBP domain
PMLHKFCF_02992 1.5e-14
PMLHKFCF_02993 4.7e-16
PMLHKFCF_02994 1.5e-14
PMLHKFCF_02995 5.5e-18
PMLHKFCF_02996 1.6e-16
PMLHKFCF_02997 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
PMLHKFCF_02998 2e-61 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
PMLHKFCF_02999 2e-198 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
PMLHKFCF_03000 0.0 macB3 V ABC transporter, ATP-binding protein
PMLHKFCF_03001 6.8e-24
PMLHKFCF_03002 1e-259 pgi 5.3.1.9 G Belongs to the GPI family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)