ORF_ID e_value Gene_name EC_number CAZy COGs Description
NICMNEDI_00001 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NICMNEDI_00002 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NICMNEDI_00003 2.4e-33 yaaA S S4 domain
NICMNEDI_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NICMNEDI_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
NICMNEDI_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NICMNEDI_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NICMNEDI_00010 4.4e-08
NICMNEDI_00011 3.3e-39 S COG NOG15344 non supervised orthologous group
NICMNEDI_00012 4.2e-169 yaaC S YaaC-like Protein
NICMNEDI_00013 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NICMNEDI_00014 8.9e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NICMNEDI_00015 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NICMNEDI_00016 1.4e-104 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NICMNEDI_00017 5.9e-25 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NICMNEDI_00018 7.3e-149 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NICMNEDI_00019 1.3e-09
NICMNEDI_00020 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NICMNEDI_00021 7.9e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NICMNEDI_00022 4e-213 yaaH M Glycoside Hydrolase Family
NICMNEDI_00023 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
NICMNEDI_00024 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NICMNEDI_00025 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NICMNEDI_00026 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NICMNEDI_00027 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NICMNEDI_00028 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NICMNEDI_00029 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NICMNEDI_00030 1.9e-28 S COG NOG14552 non supervised orthologous group
NICMNEDI_00033 1.5e-50 S COG NOG14600 non supervised orthologous group
NICMNEDI_00034 1.7e-30 csfB S Inhibitor of sigma-G Gin
NICMNEDI_00035 1.8e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NICMNEDI_00036 9.9e-203 yaaN P Belongs to the TelA family
NICMNEDI_00037 3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NICMNEDI_00038 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NICMNEDI_00039 2.2e-54 yaaQ S protein conserved in bacteria
NICMNEDI_00040 1.5e-71 yaaR S protein conserved in bacteria
NICMNEDI_00041 1.1e-181 holB 2.7.7.7 L DNA polymerase III
NICMNEDI_00042 6.1e-146 yaaT S stage 0 sporulation protein
NICMNEDI_00043 4.8e-31 yabA L Involved in initiation control of chromosome replication
NICMNEDI_00044 2.7e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
NICMNEDI_00045 3.6e-48 yazA L endonuclease containing a URI domain
NICMNEDI_00046 2.3e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NICMNEDI_00047 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NICMNEDI_00048 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NICMNEDI_00049 3.4e-143 tatD L hydrolase, TatD
NICMNEDI_00050 7.6e-167 rpfB GH23 T protein conserved in bacteria
NICMNEDI_00051 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NICMNEDI_00052 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NICMNEDI_00053 1.6e-136 yabG S peptidase
NICMNEDI_00054 7.8e-39 veg S protein conserved in bacteria
NICMNEDI_00055 8.3e-27 sspF S DNA topological change
NICMNEDI_00056 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NICMNEDI_00057 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NICMNEDI_00058 1.1e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NICMNEDI_00059 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NICMNEDI_00060 5.6e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NICMNEDI_00061 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NICMNEDI_00062 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NICMNEDI_00063 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NICMNEDI_00064 2.4e-39 yabK S Peptide ABC transporter permease
NICMNEDI_00065 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NICMNEDI_00066 1.5e-92 spoVT K stage V sporulation protein
NICMNEDI_00067 4.9e-285 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NICMNEDI_00068 3.1e-241 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NICMNEDI_00069 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NICMNEDI_00070 1.5e-49 yabP S Sporulation protein YabP
NICMNEDI_00071 9.5e-107 yabQ S spore cortex biosynthesis protein
NICMNEDI_00072 1.1e-44 divIC D Septum formation initiator
NICMNEDI_00073 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NICMNEDI_00076 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NICMNEDI_00077 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NICMNEDI_00078 1.3e-185 KLT serine threonine protein kinase
NICMNEDI_00079 2.1e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NICMNEDI_00080 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NICMNEDI_00081 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NICMNEDI_00082 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NICMNEDI_00083 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NICMNEDI_00084 1.8e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NICMNEDI_00085 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NICMNEDI_00086 7.4e-269 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NICMNEDI_00087 2.1e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NICMNEDI_00088 6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NICMNEDI_00089 6.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NICMNEDI_00090 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NICMNEDI_00091 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NICMNEDI_00092 4.1e-30 yazB K transcriptional
NICMNEDI_00093 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NICMNEDI_00094 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NICMNEDI_00099 2e-08
NICMNEDI_00104 1.4e-19 S COG NOG14552 non supervised orthologous group
NICMNEDI_00105 4.5e-08
NICMNEDI_00106 3.3e-39 S COG NOG15344 non supervised orthologous group
NICMNEDI_00107 2.9e-76 ctsR K Belongs to the CtsR family
NICMNEDI_00108 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NICMNEDI_00109 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NICMNEDI_00110 0.0 clpC O Belongs to the ClpA ClpB family
NICMNEDI_00111 2.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NICMNEDI_00112 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NICMNEDI_00113 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NICMNEDI_00114 3.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NICMNEDI_00115 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NICMNEDI_00116 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NICMNEDI_00117 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NICMNEDI_00118 7.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NICMNEDI_00119 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NICMNEDI_00120 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NICMNEDI_00121 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NICMNEDI_00122 4.4e-115 sigH K Belongs to the sigma-70 factor family
NICMNEDI_00123 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NICMNEDI_00124 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NICMNEDI_00125 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NICMNEDI_00126 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NICMNEDI_00127 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NICMNEDI_00128 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NICMNEDI_00129 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NICMNEDI_00130 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NICMNEDI_00131 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NICMNEDI_00132 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NICMNEDI_00133 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NICMNEDI_00134 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NICMNEDI_00135 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NICMNEDI_00136 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NICMNEDI_00137 4.4e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NICMNEDI_00138 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NICMNEDI_00139 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NICMNEDI_00140 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
NICMNEDI_00141 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NICMNEDI_00142 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NICMNEDI_00143 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NICMNEDI_00144 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NICMNEDI_00145 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NICMNEDI_00146 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NICMNEDI_00147 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NICMNEDI_00148 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NICMNEDI_00149 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NICMNEDI_00150 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NICMNEDI_00151 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NICMNEDI_00152 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NICMNEDI_00153 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NICMNEDI_00154 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NICMNEDI_00155 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NICMNEDI_00156 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NICMNEDI_00157 1.9e-23 rpmD J Ribosomal protein L30
NICMNEDI_00158 1.8e-72 rplO J binds to the 23S rRNA
NICMNEDI_00159 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NICMNEDI_00160 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NICMNEDI_00161 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NICMNEDI_00162 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NICMNEDI_00163 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NICMNEDI_00164 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NICMNEDI_00165 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NICMNEDI_00166 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NICMNEDI_00167 3.6e-58 rplQ J Ribosomal protein L17
NICMNEDI_00168 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NICMNEDI_00169 6.4e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NICMNEDI_00170 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NICMNEDI_00171 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NICMNEDI_00172 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NICMNEDI_00173 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NICMNEDI_00174 9e-144 ybaJ Q Methyltransferase domain
NICMNEDI_00175 9.7e-66 ybaK S Protein of unknown function (DUF2521)
NICMNEDI_00176 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NICMNEDI_00177 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NICMNEDI_00178 1.2e-84 gerD
NICMNEDI_00179 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NICMNEDI_00180 2.7e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NICMNEDI_00181 4.5e-08
NICMNEDI_00184 2e-08
NICMNEDI_00188 3.3e-39 S COG NOG15344 non supervised orthologous group
NICMNEDI_00189 1.5e-51 S COG NOG14600 non supervised orthologous group
NICMNEDI_00190 1.9e-248 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NICMNEDI_00192 3e-160 ybaS 1.1.1.58 S Na -dependent transporter
NICMNEDI_00193 2.9e-134 ybbA S Putative esterase
NICMNEDI_00194 3.3e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_00195 3.4e-175 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_00196 1.4e-165 feuA P Iron-uptake system-binding protein
NICMNEDI_00197 8e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NICMNEDI_00198 1e-237 ybbC 3.2.1.52 S protein conserved in bacteria
NICMNEDI_00199 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NICMNEDI_00200 9.2e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NICMNEDI_00201 6.4e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NICMNEDI_00202 2.5e-150 ybbH K transcriptional
NICMNEDI_00203 7.9e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NICMNEDI_00204 2.7e-85 ybbJ J acetyltransferase
NICMNEDI_00205 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NICMNEDI_00211 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NICMNEDI_00212 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NICMNEDI_00213 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NICMNEDI_00214 3e-225 ybbR S protein conserved in bacteria
NICMNEDI_00215 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NICMNEDI_00216 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NICMNEDI_00217 9.3e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NICMNEDI_00218 5.6e-115 adaA 3.2.2.21 K Transcriptional regulator
NICMNEDI_00219 9e-98 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NICMNEDI_00220 3.8e-271 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NICMNEDI_00221 0.0 ybcC S Belongs to the UPF0753 family
NICMNEDI_00222 4.2e-92 can 4.2.1.1 P carbonic anhydrase
NICMNEDI_00224 3.3e-46
NICMNEDI_00225 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NICMNEDI_00226 5.1e-50 ybzH K Helix-turn-helix domain
NICMNEDI_00227 1.9e-201 ybcL EGP Major facilitator Superfamily
NICMNEDI_00228 7e-56
NICMNEDI_00229 7.6e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NICMNEDI_00230 2.5e-121 T Transcriptional regulatory protein, C terminal
NICMNEDI_00231 7.2e-170 T His Kinase A (phospho-acceptor) domain
NICMNEDI_00233 5.7e-138 KLT Protein tyrosine kinase
NICMNEDI_00234 2.1e-149 ybdN
NICMNEDI_00235 3.7e-213 ybdO S Domain of unknown function (DUF4885)
NICMNEDI_00236 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NICMNEDI_00237 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NICMNEDI_00238 4.9e-30 ybxH S Family of unknown function (DUF5370)
NICMNEDI_00239 2.6e-149 ybxI 3.5.2.6 V beta-lactamase
NICMNEDI_00240 3.9e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NICMNEDI_00241 4.9e-41 ybyB
NICMNEDI_00242 3e-290 ybeC E amino acid
NICMNEDI_00243 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NICMNEDI_00244 7.3e-258 glpT G -transporter
NICMNEDI_00245 1.5e-34 S Protein of unknown function (DUF2651)
NICMNEDI_00246 5.1e-170 ybfA 3.4.15.5 K FR47-like protein
NICMNEDI_00247 3.5e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
NICMNEDI_00249 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NICMNEDI_00250 2.4e-159 ybfH EG EamA-like transporter family
NICMNEDI_00251 2.3e-145 msmR K AraC-like ligand binding domain
NICMNEDI_00252 8e-148 draG 3.2.2.24 O ADP-ribosylglycohydrolase
NICMNEDI_00253 4.6e-78 M nucleic acid phosphodiester bond hydrolysis
NICMNEDI_00254 1.9e-209 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NICMNEDI_00255 3.8e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NICMNEDI_00257 2.3e-167 S Alpha/beta hydrolase family
NICMNEDI_00258 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NICMNEDI_00259 2.7e-85 ybfM S SNARE associated Golgi protein
NICMNEDI_00260 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NICMNEDI_00261 4.6e-45 ybfN
NICMNEDI_00262 1e-251 S Erythromycin esterase
NICMNEDI_00263 3.9e-192 yceA S Belongs to the UPF0176 family
NICMNEDI_00264 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NICMNEDI_00265 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NICMNEDI_00267 9.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NICMNEDI_00268 1.4e-127 K UTRA
NICMNEDI_00270 3.9e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NICMNEDI_00271 4.1e-259 mmuP E amino acid
NICMNEDI_00272 3.5e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NICMNEDI_00273 9.6e-256 agcS E Sodium alanine symporter
NICMNEDI_00274 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
NICMNEDI_00275 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
NICMNEDI_00276 1.5e-169 glnL T Regulator
NICMNEDI_00277 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NICMNEDI_00278 7.4e-130 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NICMNEDI_00279 1.5e-124 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NICMNEDI_00280 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NICMNEDI_00281 8.8e-267 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NICMNEDI_00282 1.5e-124 ycbG K FCD
NICMNEDI_00283 2e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
NICMNEDI_00284 2.2e-176 ycbJ S Macrolide 2'-phosphotransferase
NICMNEDI_00285 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NICMNEDI_00286 6.4e-168 eamA1 EG spore germination
NICMNEDI_00287 1.1e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_00288 5.4e-167 T PhoQ Sensor
NICMNEDI_00289 2.2e-165 ycbN V ABC transporter, ATP-binding protein
NICMNEDI_00290 2.5e-113 S ABC-2 family transporter protein
NICMNEDI_00291 8.2e-53 ycbP S Protein of unknown function (DUF2512)
NICMNEDI_00292 2.2e-78 sleB 3.5.1.28 M Cell wall
NICMNEDI_00293 2.5e-135 ycbR T vWA found in TerF C terminus
NICMNEDI_00294 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NICMNEDI_00295 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NICMNEDI_00296 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NICMNEDI_00297 2.5e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NICMNEDI_00298 8.6e-204 ycbU E Selenocysteine lyase
NICMNEDI_00299 7.9e-226 lmrB EGP the major facilitator superfamily
NICMNEDI_00300 4.8e-102 yxaF K Transcriptional regulator
NICMNEDI_00301 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NICMNEDI_00302 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NICMNEDI_00303 7.1e-57 S RDD family
NICMNEDI_00304 4.7e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
NICMNEDI_00305 8.9e-157 2.7.13.3 T GHKL domain
NICMNEDI_00306 1.1e-124 lytR_2 T LytTr DNA-binding domain
NICMNEDI_00307 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NICMNEDI_00308 4.3e-198 natB CP ABC-2 family transporter protein
NICMNEDI_00309 1.5e-172 yccK C Aldo keto reductase
NICMNEDI_00310 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NICMNEDI_00311 2.1e-271 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NICMNEDI_00312 2.9e-255 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NICMNEDI_00313 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
NICMNEDI_00314 1e-172 S response regulator aspartate phosphatase
NICMNEDI_00315 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
NICMNEDI_00316 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NICMNEDI_00317 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
NICMNEDI_00318 1.4e-130 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NICMNEDI_00319 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NICMNEDI_00320 5.2e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NICMNEDI_00321 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NICMNEDI_00322 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NICMNEDI_00323 2.3e-107 yceE T proteins involved in stress response, homologs of TerZ and
NICMNEDI_00324 1.4e-136 terC P Protein of unknown function (DUF475)
NICMNEDI_00325 0.0 yceG S Putative component of 'biosynthetic module'
NICMNEDI_00326 2e-192 yceH P Belongs to the TelA family
NICMNEDI_00327 4.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
NICMNEDI_00328 9.1e-204 yceJ EGP Uncharacterised MFS-type transporter YbfB
NICMNEDI_00329 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NICMNEDI_00330 5.1e-229 proV 3.6.3.32 E glycine betaine
NICMNEDI_00331 1.3e-127 opuAB P glycine betaine
NICMNEDI_00332 5.3e-164 opuAC E glycine betaine
NICMNEDI_00333 4.1e-217 amhX S amidohydrolase
NICMNEDI_00334 4.3e-256 ycgA S Membrane
NICMNEDI_00335 7e-81 ycgB
NICMNEDI_00336 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NICMNEDI_00337 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NICMNEDI_00338 1e-290 lctP C L-lactate permease
NICMNEDI_00339 5.6e-262 mdr EGP Major facilitator Superfamily
NICMNEDI_00340 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
NICMNEDI_00341 1.5e-112 ycgF E Lysine exporter protein LysE YggA
NICMNEDI_00342 9.9e-151 yqcI S YqcI/YcgG family
NICMNEDI_00343 4.4e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NICMNEDI_00344 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NICMNEDI_00345 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NICMNEDI_00346 2.1e-108 tmrB S AAA domain
NICMNEDI_00348 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NICMNEDI_00349 4e-144 yafE Q ubiE/COQ5 methyltransferase family
NICMNEDI_00350 1.8e-176 oxyR3 K LysR substrate binding domain
NICMNEDI_00351 1.4e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NICMNEDI_00352 6.4e-145 ycgL S Predicted nucleotidyltransferase
NICMNEDI_00353 5.1e-170 ycgM E Proline dehydrogenase
NICMNEDI_00354 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NICMNEDI_00355 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NICMNEDI_00356 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NICMNEDI_00357 2.6e-147 ycgQ S membrane
NICMNEDI_00358 1.2e-139 ycgR S permeases
NICMNEDI_00359 1.9e-43 I alpha/beta hydrolase fold
NICMNEDI_00360 5.1e-73 I alpha/beta hydrolase fold
NICMNEDI_00361 1.2e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NICMNEDI_00362 1.9e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NICMNEDI_00363 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NICMNEDI_00364 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NICMNEDI_00365 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NICMNEDI_00366 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NICMNEDI_00367 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
NICMNEDI_00368 1.5e-169 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NICMNEDI_00369 7.9e-108 yciB M ErfK YbiS YcfS YnhG
NICMNEDI_00370 1.4e-228 yciC S GTPases (G3E family)
NICMNEDI_00371 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NICMNEDI_00372 8.9e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NICMNEDI_00374 6e-36 yckC S membrane
NICMNEDI_00375 1.1e-50 yckD S Protein of unknown function (DUF2680)
NICMNEDI_00376 4.1e-45 K MarR family
NICMNEDI_00377 9.3e-24
NICMNEDI_00378 2.7e-121 S AAA domain
NICMNEDI_00379 4e-294 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NICMNEDI_00380 6.5e-69 nin S Competence protein J (ComJ)
NICMNEDI_00381 3e-70 nucA M Deoxyribonuclease NucA/NucB
NICMNEDI_00382 5.1e-187 tlpC 2.7.13.3 NT chemotaxis protein
NICMNEDI_00383 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NICMNEDI_00384 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NICMNEDI_00385 1.3e-63 hxlR K transcriptional
NICMNEDI_00386 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_00387 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_00388 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NICMNEDI_00389 8.9e-12 srfAD Q thioesterase
NICMNEDI_00390 2e-114 srfAD Q thioesterase
NICMNEDI_00391 8.7e-96 EGP Major Facilitator Superfamily
NICMNEDI_00392 3.5e-103 EGP Major Facilitator Superfamily
NICMNEDI_00393 1.5e-87 S YcxB-like protein
NICMNEDI_00394 1.3e-160 ycxC EG EamA-like transporter family
NICMNEDI_00395 1.3e-251 ycxD K GntR family transcriptional regulator
NICMNEDI_00396 1.7e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NICMNEDI_00397 1.7e-114 yczE S membrane
NICMNEDI_00398 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NICMNEDI_00399 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NICMNEDI_00400 2e-125 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NICMNEDI_00401 1.9e-161 bsdA K LysR substrate binding domain
NICMNEDI_00402 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NICMNEDI_00403 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NICMNEDI_00404 4e-39 bsdD 4.1.1.61 S response to toxic substance
NICMNEDI_00405 5.6e-80 yclD
NICMNEDI_00406 3.1e-132 yclE 3.4.11.5 S Alpha beta hydrolase
NICMNEDI_00407 1.3e-263 dtpT E amino acid peptide transporter
NICMNEDI_00408 1.1e-298 yclG M Pectate lyase superfamily protein
NICMNEDI_00410 3.5e-278 gerKA EG Spore germination protein
NICMNEDI_00411 3.1e-231 gerKC S spore germination
NICMNEDI_00412 1.7e-196 gerKB F Spore germination protein
NICMNEDI_00413 4.7e-120 yclH P ABC transporter
NICMNEDI_00414 3.7e-202 yclI V ABC transporter (permease) YclI
NICMNEDI_00415 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_00416 4.4e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NICMNEDI_00417 2e-70 S aspartate phosphatase
NICMNEDI_00420 8.3e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
NICMNEDI_00421 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_00422 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_00423 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NICMNEDI_00424 1.2e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NICMNEDI_00425 1.6e-250 ycnB EGP Major facilitator Superfamily
NICMNEDI_00426 5.5e-153 ycnC K Transcriptional regulator
NICMNEDI_00427 1.7e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NICMNEDI_00428 1.6e-45 ycnE S Monooxygenase
NICMNEDI_00429 8.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NICMNEDI_00430 5.1e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NICMNEDI_00431 4.1e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NICMNEDI_00432 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NICMNEDI_00433 6.1e-149 glcU U Glucose uptake
NICMNEDI_00434 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NICMNEDI_00435 9.3e-99 ycnI S protein conserved in bacteria
NICMNEDI_00436 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NICMNEDI_00437 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NICMNEDI_00438 1.7e-52
NICMNEDI_00439 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NICMNEDI_00440 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NICMNEDI_00441 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NICMNEDI_00442 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NICMNEDI_00444 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NICMNEDI_00445 1.4e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NICMNEDI_00446 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NICMNEDI_00448 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NICMNEDI_00449 2e-138 ycsF S Belongs to the UPF0271 (lamB) family
NICMNEDI_00450 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NICMNEDI_00451 9e-147 ycsI S Belongs to the D-glutamate cyclase family
NICMNEDI_00452 2.1e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NICMNEDI_00453 2.5e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NICMNEDI_00454 1.2e-132 kipR K Transcriptional regulator
NICMNEDI_00455 8.7e-116 ycsK E anatomical structure formation involved in morphogenesis
NICMNEDI_00457 5.4e-49 yczJ S biosynthesis
NICMNEDI_00458 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NICMNEDI_00459 8.3e-173 ydhF S Oxidoreductase
NICMNEDI_00460 0.0 mtlR K transcriptional regulator, MtlR
NICMNEDI_00461 7.9e-293 ydaB IQ acyl-CoA ligase
NICMNEDI_00462 3.1e-99 ydaC Q Methyltransferase domain
NICMNEDI_00463 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NICMNEDI_00464 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NICMNEDI_00465 6.1e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NICMNEDI_00466 6.8e-77 ydaG 1.4.3.5 S general stress protein
NICMNEDI_00467 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NICMNEDI_00468 3.3e-46 ydzA EGP Major facilitator Superfamily
NICMNEDI_00469 2.5e-74 lrpC K Transcriptional regulator
NICMNEDI_00470 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NICMNEDI_00471 3.8e-204 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NICMNEDI_00472 4.2e-150 ydaK T Diguanylate cyclase, GGDEF domain
NICMNEDI_00473 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NICMNEDI_00474 1.3e-232 ydaM M Glycosyl transferase family group 2
NICMNEDI_00475 0.0 ydaN S Bacterial cellulose synthase subunit
NICMNEDI_00476 0.0 ydaO E amino acid
NICMNEDI_00477 1.1e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NICMNEDI_00478 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NICMNEDI_00480 2.1e-39
NICMNEDI_00481 1.7e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NICMNEDI_00483 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NICMNEDI_00484 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NICMNEDI_00486 3.1e-56 ydbB G Cupin domain
NICMNEDI_00487 1.8e-62 ydbC S Domain of unknown function (DUF4937
NICMNEDI_00488 3.5e-154 ydbD P Catalase
NICMNEDI_00489 1.3e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NICMNEDI_00490 4.3e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NICMNEDI_00491 3.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
NICMNEDI_00492 4.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NICMNEDI_00493 3.7e-180 ydbI S AI-2E family transporter
NICMNEDI_00494 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
NICMNEDI_00495 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NICMNEDI_00496 2.7e-52 ydbL
NICMNEDI_00497 1.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NICMNEDI_00498 1.1e-18 S Fur-regulated basic protein B
NICMNEDI_00499 2.2e-07 S Fur-regulated basic protein A
NICMNEDI_00500 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NICMNEDI_00501 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NICMNEDI_00502 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NICMNEDI_00503 1e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NICMNEDI_00504 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NICMNEDI_00505 2.1e-82 ydbS S Bacterial PH domain
NICMNEDI_00506 2.4e-262 ydbT S Membrane
NICMNEDI_00507 6.9e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NICMNEDI_00508 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NICMNEDI_00509 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NICMNEDI_00510 9.6e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NICMNEDI_00511 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NICMNEDI_00512 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NICMNEDI_00513 1.3e-143 rsbR T Positive regulator of sigma-B
NICMNEDI_00514 5.2e-57 rsbS T antagonist
NICMNEDI_00515 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NICMNEDI_00516 7.1e-189 rsbU 3.1.3.3 KT phosphatase
NICMNEDI_00517 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NICMNEDI_00518 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NICMNEDI_00519 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NICMNEDI_00520 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NICMNEDI_00521 5.7e-15 S Polyketide cyclase / dehydrase and lipid transport
NICMNEDI_00522 4.3e-82 ydcG S EVE domain
NICMNEDI_00523 2.3e-75 ydcH K helix_turn_helix multiple antibiotic resistance protein
NICMNEDI_00524 0.0 yhgF K COG2183 Transcriptional accessory protein
NICMNEDI_00525 1.5e-82 ydcK S Belongs to the SprT family
NICMNEDI_00533 1.2e-183 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NICMNEDI_00534 2.4e-71 lrpA K transcriptional
NICMNEDI_00535 1.9e-77 lrpB K transcriptional
NICMNEDI_00536 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
NICMNEDI_00537 1.2e-61 yddR S Zn-dependent hydrolases of the beta-lactamase fold
NICMNEDI_00538 3.7e-27 yddR S Zn-dependent hydrolases of the beta-lactamase fold
NICMNEDI_00539 2.3e-224 ydeG EGP Major facilitator Superfamily
NICMNEDI_00540 2.1e-68 L HNH nucleases
NICMNEDI_00541 9.8e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NICMNEDI_00542 8.7e-30 cspL K Cold shock
NICMNEDI_00543 1.2e-77 carD K Transcription factor
NICMNEDI_00545 1.5e-163 rhaS5 K AraC-like ligand binding domain
NICMNEDI_00546 1.4e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NICMNEDI_00547 8.1e-165 ydeE K AraC family transcriptional regulator
NICMNEDI_00548 3.6e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NICMNEDI_00549 9.3e-218 ydeG EGP Major facilitator superfamily
NICMNEDI_00550 2.1e-45 ydeH
NICMNEDI_00551 2.3e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NICMNEDI_00552 2.1e-112
NICMNEDI_00553 5.9e-152 ydeK EG -transporter
NICMNEDI_00554 3.1e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NICMNEDI_00555 4.2e-74 maoC I N-terminal half of MaoC dehydratase
NICMNEDI_00556 5.1e-102 ydeN S Serine hydrolase
NICMNEDI_00557 9.8e-55 K HxlR-like helix-turn-helix
NICMNEDI_00558 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NICMNEDI_00559 8.2e-57 arsR K transcriptional
NICMNEDI_00560 4.8e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NICMNEDI_00561 1.8e-147 ydfB J GNAT acetyltransferase
NICMNEDI_00562 2e-161 ydfC EG EamA-like transporter family
NICMNEDI_00563 2.3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NICMNEDI_00564 8.9e-185 gadB 4.1.1.105, 4.1.1.28, 4.1.1.29 E Pyridoxal-dependent decarboxylase conserved domain
NICMNEDI_00565 1.4e-115 ydfE S Flavin reductase like domain
NICMNEDI_00566 3.9e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NICMNEDI_00567 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NICMNEDI_00568 7.7e-179 ydfH 2.7.13.3 T Histidine kinase
NICMNEDI_00569 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NICMNEDI_00570 0.0 ydfJ S drug exporters of the RND superfamily
NICMNEDI_00571 1.9e-116 S Protein of unknown function (DUF554)
NICMNEDI_00572 4.6e-146 K Bacterial transcription activator, effector binding domain
NICMNEDI_00573 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NICMNEDI_00574 7.1e-107 ydfN C nitroreductase
NICMNEDI_00575 8.9e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NICMNEDI_00576 1.2e-62 mhqP S DoxX
NICMNEDI_00577 5e-54 traF CO Thioredoxin
NICMNEDI_00578 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NICMNEDI_00579 8.2e-29
NICMNEDI_00581 6.5e-46 ydfR S Protein of unknown function (DUF421)
NICMNEDI_00582 2.3e-30 ydfR S Protein of unknown function (DUF421)
NICMNEDI_00583 1.5e-121 ydfS S Protein of unknown function (DUF421)
NICMNEDI_00584 1.1e-66 cotP O Belongs to the small heat shock protein (HSP20) family
NICMNEDI_00585 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
NICMNEDI_00586 2.7e-34 ydgB S Spore germination protein gerPA/gerPF
NICMNEDI_00587 8.4e-97 K Bacterial regulatory proteins, tetR family
NICMNEDI_00588 2.1e-52 S DoxX-like family
NICMNEDI_00589 1.6e-82 yycN 2.3.1.128 K Acetyltransferase
NICMNEDI_00590 9.8e-305 expZ S ABC transporter
NICMNEDI_00591 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NICMNEDI_00592 1.7e-88 dinB S DinB family
NICMNEDI_00593 2.7e-79 K helix_turn_helix multiple antibiotic resistance protein
NICMNEDI_00594 0.0 ydgH S drug exporters of the RND superfamily
NICMNEDI_00595 1e-113 drgA C nitroreductase
NICMNEDI_00596 2.4e-69 ydgJ K Winged helix DNA-binding domain
NICMNEDI_00597 6.3e-208 tcaB EGP Major facilitator Superfamily
NICMNEDI_00598 1.2e-121 ydhB S membrane transporter protein
NICMNEDI_00599 2.5e-121 ydhC K FCD
NICMNEDI_00600 4.8e-243 ydhD M Glycosyl hydrolase
NICMNEDI_00601 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NICMNEDI_00602 2.3e-125
NICMNEDI_00603 1.7e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NICMNEDI_00604 1.6e-66 frataxin S Domain of unknown function (DU1801)
NICMNEDI_00606 3.3e-83 K Acetyltransferase (GNAT) domain
NICMNEDI_00607 6.5e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NICMNEDI_00608 2.3e-96 ydhK M Protein of unknown function (DUF1541)
NICMNEDI_00609 4.3e-198 pbuE EGP Major facilitator Superfamily
NICMNEDI_00610 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NICMNEDI_00611 4.3e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NICMNEDI_00612 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NICMNEDI_00613 5.4e-280 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NICMNEDI_00614 1.1e-132 ydhQ K UTRA
NICMNEDI_00615 1.2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NICMNEDI_00616 9.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
NICMNEDI_00617 2.9e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NICMNEDI_00618 2.3e-156 ydhU P Catalase
NICMNEDI_00621 1.4e-19 S COG NOG14552 non supervised orthologous group
NICMNEDI_00622 4.5e-08
NICMNEDI_00623 3.3e-39 S COG NOG15344 non supervised orthologous group
NICMNEDI_00624 7.8e-08
NICMNEDI_00626 4.2e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NICMNEDI_00627 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NICMNEDI_00628 4.2e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NICMNEDI_00629 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NICMNEDI_00630 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NICMNEDI_00631 0.0 ydiF S ABC transporter
NICMNEDI_00632 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NICMNEDI_00633 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NICMNEDI_00634 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NICMNEDI_00635 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NICMNEDI_00636 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NICMNEDI_00637 7.9e-129 ydiL S CAAX protease self-immunity
NICMNEDI_00638 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NICMNEDI_00639 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NICMNEDI_00640 8.2e-34 D Anion-transporting ATPase
NICMNEDI_00643 3.3e-154 ydjC S Abhydrolase domain containing 18
NICMNEDI_00644 0.0 K NB-ARC domain
NICMNEDI_00645 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
NICMNEDI_00646 6.7e-254 gutA G MFS/sugar transport protein
NICMNEDI_00647 3.1e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NICMNEDI_00648 3.3e-113 pspA KT Phage shock protein A
NICMNEDI_00649 9.8e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NICMNEDI_00650 3.4e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NICMNEDI_00651 9e-149 ydjI S virion core protein (lumpy skin disease virus)
NICMNEDI_00652 1e-94 S Ion transport 2 domain protein
NICMNEDI_00653 9.8e-22 S Ion transport 2 domain protein
NICMNEDI_00654 6.6e-257 iolT EGP Major facilitator Superfamily
NICMNEDI_00655 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NICMNEDI_00656 4.5e-64 ydjM M Lytic transglycolase
NICMNEDI_00657 1.6e-151 ydjN U Involved in the tonB-independent uptake of proteins
NICMNEDI_00659 1.4e-34 ydjO S Cold-inducible protein YdjO
NICMNEDI_00660 2.4e-155 ydjP I Alpha/beta hydrolase family
NICMNEDI_00661 2.2e-174 yeaA S Protein of unknown function (DUF4003)
NICMNEDI_00662 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NICMNEDI_00663 4.4e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NICMNEDI_00664 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NICMNEDI_00665 5e-176 yeaC S COG0714 MoxR-like ATPases
NICMNEDI_00666 1.2e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NICMNEDI_00667 0.0 yebA E COG1305 Transglutaminase-like enzymes
NICMNEDI_00668 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NICMNEDI_00669 1.2e-83 K Belongs to the sigma-70 factor family. ECF subfamily
NICMNEDI_00670 5.4e-173 S Domain of unknown function (DUF4179)
NICMNEDI_00671 8.3e-55 S Domain of unknown function (DUF4179)
NICMNEDI_00672 1e-211 pbuG S permease
NICMNEDI_00673 4.4e-117 yebC M Membrane
NICMNEDI_00675 8.9e-93 yebE S UPF0316 protein
NICMNEDI_00676 8e-28 yebG S NETI protein
NICMNEDI_00677 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NICMNEDI_00678 3.8e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NICMNEDI_00679 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NICMNEDI_00680 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NICMNEDI_00681 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NICMNEDI_00682 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NICMNEDI_00683 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NICMNEDI_00684 3.6e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NICMNEDI_00685 1.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NICMNEDI_00686 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NICMNEDI_00687 3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NICMNEDI_00688 1.1e-231 purD 6.3.4.13 F Belongs to the GARS family
NICMNEDI_00689 1e-72 K helix_turn_helix ASNC type
NICMNEDI_00690 2e-228 yjeH E Amino acid permease
NICMNEDI_00691 2.7e-27 S Protein of unknown function (DUF2892)
NICMNEDI_00692 0.0 yerA 3.5.4.2 F adenine deaminase
NICMNEDI_00693 3.7e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
NICMNEDI_00694 4.8e-51 yerC S protein conserved in bacteria
NICMNEDI_00695 7.9e-152 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NICMNEDI_00697 1.1e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NICMNEDI_00698 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NICMNEDI_00699 2.2e-33 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NICMNEDI_00700 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NICMNEDI_00701 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NICMNEDI_00702 1.7e-195 yerI S homoserine kinase type II (protein kinase fold)
NICMNEDI_00703 9.3e-43 sapB S MgtC SapB transporter
NICMNEDI_00704 2.4e-60 sapB S MgtC SapB transporter
NICMNEDI_00705 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NICMNEDI_00706 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NICMNEDI_00707 5.6e-08 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NICMNEDI_00708 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NICMNEDI_00709 5.7e-147 yerO K Transcriptional regulator
NICMNEDI_00710 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NICMNEDI_00711 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NICMNEDI_00712 5.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NICMNEDI_00713 1.8e-34
NICMNEDI_00714 6.7e-78 S Protein of unknown function, DUF600
NICMNEDI_00715 1.7e-52 S Protein of unknown function, DUF600
NICMNEDI_00716 4.2e-51 S Protein of unknown function, DUF600
NICMNEDI_00717 0.0 L nucleic acid phosphodiester bond hydrolysis
NICMNEDI_00719 3.8e-96 L endonuclease activity
NICMNEDI_00720 1.2e-51
NICMNEDI_00721 4.1e-209 S Tetratricopeptide repeat
NICMNEDI_00723 2.7e-126 yeeN K transcriptional regulatory protein
NICMNEDI_00725 1.8e-99 dhaR3 K Transcriptional regulator
NICMNEDI_00726 3.4e-79 yesE S SnoaL-like domain
NICMNEDI_00727 1.3e-151 yesF GM NAD(P)H-binding
NICMNEDI_00728 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NICMNEDI_00729 1.5e-45 cotJB S CotJB protein
NICMNEDI_00730 5.2e-104 cotJC P Spore Coat
NICMNEDI_00731 1.3e-101 yesJ K Acetyltransferase (GNAT) family
NICMNEDI_00733 2.9e-100 yesL S Protein of unknown function, DUF624
NICMNEDI_00734 0.0 yesM 2.7.13.3 T Histidine kinase
NICMNEDI_00735 1.2e-202 yesN K helix_turn_helix, arabinose operon control protein
NICMNEDI_00736 9.5e-247 yesO G Bacterial extracellular solute-binding protein
NICMNEDI_00737 1e-170 yesP G Binding-protein-dependent transport system inner membrane component
NICMNEDI_00738 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
NICMNEDI_00739 2.7e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NICMNEDI_00740 0.0 yesS K Transcriptional regulator
NICMNEDI_00741 7.9e-131 E GDSL-like Lipase/Acylhydrolase
NICMNEDI_00742 1.6e-128 yesU S Domain of unknown function (DUF1961)
NICMNEDI_00743 1.5e-112 yesV S Protein of unknown function, DUF624
NICMNEDI_00744 1.1e-16 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NICMNEDI_00745 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NICMNEDI_00746 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NICMNEDI_00747 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
NICMNEDI_00748 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NICMNEDI_00749 3.9e-69 yetA
NICMNEDI_00750 0.0 yetA
NICMNEDI_00751 1.2e-288 lplA G Bacterial extracellular solute-binding protein
NICMNEDI_00752 3.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NICMNEDI_00753 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
NICMNEDI_00754 7.1e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NICMNEDI_00755 5.2e-122 yetF S membrane
NICMNEDI_00756 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NICMNEDI_00757 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NICMNEDI_00758 2.4e-34
NICMNEDI_00759 1.9e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NICMNEDI_00760 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NICMNEDI_00761 5.3e-105 yetJ S Belongs to the BI1 family
NICMNEDI_00762 1.2e-158 yetK EG EamA-like transporter family
NICMNEDI_00763 2.1e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
NICMNEDI_00764 3e-209 yetM CH FAD binding domain
NICMNEDI_00766 1.6e-194 yetN S Protein of unknown function (DUF3900)
NICMNEDI_00767 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NICMNEDI_00768 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NICMNEDI_00769 1.1e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
NICMNEDI_00770 3.2e-172 yfnG 4.2.1.45 M dehydratase
NICMNEDI_00771 1e-178 yfnF M Nucleotide-diphospho-sugar transferase
NICMNEDI_00772 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NICMNEDI_00773 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
NICMNEDI_00774 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
NICMNEDI_00775 8.1e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NICMNEDI_00776 6.4e-241 yfnA E amino acid
NICMNEDI_00777 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NICMNEDI_00778 1.1e-113 yfmS NT chemotaxis protein
NICMNEDI_00779 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NICMNEDI_00780 2.6e-74 yfmQ S Uncharacterised protein from bacillus cereus group
NICMNEDI_00781 1.4e-69 yfmP K transcriptional
NICMNEDI_00782 6.2e-208 yfmO EGP Major facilitator Superfamily
NICMNEDI_00783 4.7e-59 isp O Subtilase family
NICMNEDI_00784 6.4e-19
NICMNEDI_00786 6.3e-57
NICMNEDI_00787 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NICMNEDI_00788 2.6e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NICMNEDI_00789 1.8e-75 yfmK 2.3.1.128 K acetyltransferase
NICMNEDI_00790 7.9e-188 yfmJ S N-terminal domain of oxidoreductase
NICMNEDI_00791 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NICMNEDI_00792 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_00793 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_00794 2.1e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NICMNEDI_00795 2.9e-24 S Protein of unknown function (DUF3212)
NICMNEDI_00796 7.6e-58 yflT S Heat induced stress protein YflT
NICMNEDI_00797 3.2e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NICMNEDI_00798 7.1e-235 yflS P Sodium:sulfate symporter transmembrane region
NICMNEDI_00799 2.1e-267 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NICMNEDI_00800 2.2e-117 citT T response regulator
NICMNEDI_00801 6.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
NICMNEDI_00802 8.5e-227 citM C Citrate transporter
NICMNEDI_00803 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NICMNEDI_00804 4.3e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NICMNEDI_00805 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NICMNEDI_00806 2.2e-66 yflK S protein conserved in bacteria
NICMNEDI_00807 4e-18 yflJ S Protein of unknown function (DUF2639)
NICMNEDI_00808 4.1e-19 yflI
NICMNEDI_00809 1.5e-49 yflH S Protein of unknown function (DUF3243)
NICMNEDI_00810 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NICMNEDI_00811 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NICMNEDI_00812 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NICMNEDI_00813 6e-67 yhdN S Domain of unknown function (DUF1992)
NICMNEDI_00814 1.8e-76 agcS_1 E Sodium alanine symporter
NICMNEDI_00815 5.1e-140 agcS_1 E Sodium alanine symporter
NICMNEDI_00816 2.2e-25 yfkQ EG Spore germination protein
NICMNEDI_00817 3.2e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NICMNEDI_00818 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NICMNEDI_00819 3.9e-133 treR K transcriptional
NICMNEDI_00820 1.1e-124 yfkO C nitroreductase
NICMNEDI_00821 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NICMNEDI_00822 4.7e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
NICMNEDI_00823 1.2e-203 ydiM EGP Major facilitator Superfamily
NICMNEDI_00824 3.9e-28 yfkK S Belongs to the UPF0435 family
NICMNEDI_00825 2.2e-51 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NICMNEDI_00826 2.4e-50 yfkI S gas vesicle protein
NICMNEDI_00827 1.3e-143 yihY S Belongs to the UPF0761 family
NICMNEDI_00828 5e-08
NICMNEDI_00829 1.3e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NICMNEDI_00830 6.1e-183 cax P COG0387 Ca2 H antiporter
NICMNEDI_00831 1.2e-146 yfkD S YfkD-like protein
NICMNEDI_00832 6e-149 yfkC M Mechanosensitive ion channel
NICMNEDI_00833 5.4e-222 yfkA S YfkB-like domain
NICMNEDI_00834 1.1e-26 yfjT
NICMNEDI_00835 9.9e-154 pdaA G deacetylase
NICMNEDI_00836 5.7e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NICMNEDI_00837 1.7e-184 corA P Mediates influx of magnesium ions
NICMNEDI_00838 6.5e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NICMNEDI_00839 9e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NICMNEDI_00840 3.9e-44 S YfzA-like protein
NICMNEDI_00841 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NICMNEDI_00842 9.6e-85 yfjM S Psort location Cytoplasmic, score
NICMNEDI_00843 4.3e-28 yfjL
NICMNEDI_00844 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NICMNEDI_00845 3.8e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NICMNEDI_00846 9.3e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NICMNEDI_00847 1.6e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NICMNEDI_00848 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NICMNEDI_00849 1.2e-25 sspH S Belongs to the SspH family
NICMNEDI_00850 4e-56 yfjF S UPF0060 membrane protein
NICMNEDI_00851 8.1e-86 S Family of unknown function (DUF5381)
NICMNEDI_00852 1.2e-124 yfjC
NICMNEDI_00853 2.8e-171 yfjB
NICMNEDI_00854 3.3e-44 yfjA S Belongs to the WXG100 family
NICMNEDI_00855 6.4e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NICMNEDI_00856 1e-139 glvR K Helix-turn-helix domain, rpiR family
NICMNEDI_00857 8e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NICMNEDI_00858 0.0 yobO M COG5434 Endopolygalacturonase
NICMNEDI_00859 3.2e-306 yfiB3 V ABC transporter
NICMNEDI_00860 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NICMNEDI_00861 9.8e-65 mhqP S DoxX
NICMNEDI_00862 3.1e-161 yfiE 1.13.11.2 S glyoxalase
NICMNEDI_00863 7.7e-187 yxjM T Histidine kinase
NICMNEDI_00864 2.8e-109 KT LuxR family transcriptional regulator
NICMNEDI_00865 1.2e-166 V ABC transporter, ATP-binding protein
NICMNEDI_00866 2.3e-210 V ABC-2 family transporter protein
NICMNEDI_00867 2.1e-205 V COG0842 ABC-type multidrug transport system, permease component
NICMNEDI_00868 8.3e-99 padR K transcriptional
NICMNEDI_00869 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NICMNEDI_00870 2.2e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NICMNEDI_00871 7.1e-107 yfiR K Transcriptional regulator
NICMNEDI_00872 2.2e-68 yfiS EGP Major facilitator Superfamily
NICMNEDI_00873 8.1e-115 yfiS EGP Major facilitator Superfamily
NICMNEDI_00874 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
NICMNEDI_00875 4.5e-283 yfiU EGP Major facilitator Superfamily
NICMNEDI_00876 4.9e-79 yfiV K transcriptional
NICMNEDI_00877 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NICMNEDI_00878 2.1e-177 yfiY P ABC transporter substrate-binding protein
NICMNEDI_00879 9.9e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_00880 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_00881 3.7e-165 yfhB 5.3.3.17 S PhzF family
NICMNEDI_00882 3.1e-106 yfhC C nitroreductase
NICMNEDI_00883 2.1e-25 yfhD S YfhD-like protein
NICMNEDI_00885 1.2e-171 yfhF S nucleoside-diphosphate sugar epimerase
NICMNEDI_00886 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NICMNEDI_00887 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NICMNEDI_00889 1.1e-209 yfhI EGP Major facilitator Superfamily
NICMNEDI_00890 6.2e-20 sspK S reproduction
NICMNEDI_00891 1.3e-44 yfhJ S WVELL protein
NICMNEDI_00892 5.2e-87 batE T Bacterial SH3 domain homologues
NICMNEDI_00893 1.7e-50 yfhL S SdpI/YhfL protein family
NICMNEDI_00894 1.3e-170 yfhM S Alpha beta hydrolase
NICMNEDI_00895 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NICMNEDI_00896 0.0 yfhO S Bacterial membrane protein YfhO
NICMNEDI_00897 1.2e-185 yfhP S membrane-bound metal-dependent
NICMNEDI_00898 1.1e-210 mutY L A G-specific
NICMNEDI_00899 6.9e-36 yfhS
NICMNEDI_00900 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NICMNEDI_00901 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NICMNEDI_00902 3.3e-37 ygaB S YgaB-like protein
NICMNEDI_00903 1.3e-104 ygaC J Belongs to the UPF0374 family
NICMNEDI_00904 3.1e-301 ygaD V ABC transporter
NICMNEDI_00905 8.7e-180 ygaE S Membrane
NICMNEDI_00906 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NICMNEDI_00907 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
NICMNEDI_00908 4e-80 perR P Belongs to the Fur family
NICMNEDI_00909 2.8e-55 ygzB S UPF0295 protein
NICMNEDI_00910 6.7e-167 ygxA S Nucleotidyltransferase-like
NICMNEDI_00911 3.3e-39 S COG NOG15344 non supervised orthologous group
NICMNEDI_00912 1.5e-51 S COG NOG14600 non supervised orthologous group
NICMNEDI_00917 7.8e-08
NICMNEDI_00925 2e-08
NICMNEDI_00929 1.3e-142 spo0M S COG4326 Sporulation control protein
NICMNEDI_00930 1.2e-26
NICMNEDI_00931 6.9e-71 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NICMNEDI_00932 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NICMNEDI_00933 9.2e-23 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NICMNEDI_00934 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NICMNEDI_00935 4.3e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NICMNEDI_00936 2.1e-169 ssuA M Sulfonate ABC transporter
NICMNEDI_00937 1.6e-146 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NICMNEDI_00938 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NICMNEDI_00940 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NICMNEDI_00941 4.2e-75 ygaO
NICMNEDI_00942 4.4e-29 K Transcriptional regulator
NICMNEDI_00944 3.3e-112 yhzB S B3/4 domain
NICMNEDI_00945 3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NICMNEDI_00946 1.7e-176 yhbB S Putative amidase domain
NICMNEDI_00947 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NICMNEDI_00948 1.2e-109 yhbD K Protein of unknown function (DUF4004)
NICMNEDI_00949 7.8e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NICMNEDI_00950 1.1e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NICMNEDI_00951 0.0 prkA T Ser protein kinase
NICMNEDI_00952 2.5e-225 yhbH S Belongs to the UPF0229 family
NICMNEDI_00953 2.2e-76 yhbI K DNA-binding transcription factor activity
NICMNEDI_00954 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NICMNEDI_00955 9.9e-270 yhcA EGP Major facilitator Superfamily
NICMNEDI_00956 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NICMNEDI_00957 2.8e-37 yhcC
NICMNEDI_00958 6e-55
NICMNEDI_00959 6.6e-60 yhcF K Transcriptional regulator
NICMNEDI_00960 1.7e-120 yhcG V ABC transporter, ATP-binding protein
NICMNEDI_00961 1.4e-164 yhcH V ABC transporter, ATP-binding protein
NICMNEDI_00962 6.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NICMNEDI_00963 6.7e-30 cspB K Cold-shock protein
NICMNEDI_00964 2.4e-150 metQ M Belongs to the nlpA lipoprotein family
NICMNEDI_00965 4.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NICMNEDI_00966 2.4e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NICMNEDI_00967 8.3e-78 S Protein of unknown function (DUF2812)
NICMNEDI_00968 1.2e-49 K Transcriptional regulator PadR-like family
NICMNEDI_00969 4.1e-40 yhcM
NICMNEDI_00970 2.2e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NICMNEDI_00971 1.4e-165 yhcP
NICMNEDI_00972 5.2e-100 yhcQ M Spore coat protein
NICMNEDI_00973 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NICMNEDI_00974 4.6e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NICMNEDI_00975 3e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NICMNEDI_00976 9.3e-68 yhcU S Family of unknown function (DUF5365)
NICMNEDI_00977 9.9e-68 yhcV S COG0517 FOG CBS domain
NICMNEDI_00978 1.3e-119 yhcW 5.4.2.6 S hydrolase
NICMNEDI_00979 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NICMNEDI_00980 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NICMNEDI_00981 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NICMNEDI_00982 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NICMNEDI_00983 3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NICMNEDI_00984 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NICMNEDI_00985 1.7e-268 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NICMNEDI_00986 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
NICMNEDI_00987 2.2e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NICMNEDI_00988 1.2e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
NICMNEDI_00989 1.2e-38 yhdB S YhdB-like protein
NICMNEDI_00990 1.8e-53 yhdC S Protein of unknown function (DUF3889)
NICMNEDI_00991 1.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NICMNEDI_00992 1e-75 nsrR K Transcriptional regulator
NICMNEDI_00993 1.5e-238 ygxB M Conserved TM helix
NICMNEDI_00994 6.3e-276 ycgB S Stage V sporulation protein R
NICMNEDI_00995 8.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NICMNEDI_00996 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NICMNEDI_00997 3.8e-162 citR K Transcriptional regulator
NICMNEDI_00998 5.9e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
NICMNEDI_00999 8.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NICMNEDI_01000 1e-249 yhdG E amino acid
NICMNEDI_01001 2.2e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NICMNEDI_01002 1.5e-239 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NICMNEDI_01003 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NICMNEDI_01004 8.1e-45 yhdK S Sigma-M inhibitor protein
NICMNEDI_01005 1.5e-197 yhdL S Sigma factor regulator N-terminal
NICMNEDI_01006 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NICMNEDI_01007 4.9e-190 yhdN C Aldo keto reductase
NICMNEDI_01008 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NICMNEDI_01009 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NICMNEDI_01010 4.7e-74 cueR K transcriptional
NICMNEDI_01011 2e-222 yhdR 2.6.1.1 E Aminotransferase
NICMNEDI_01012 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NICMNEDI_01013 3.2e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NICMNEDI_01014 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NICMNEDI_01015 1.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NICMNEDI_01017 9.9e-184 yhdY M Mechanosensitive ion channel
NICMNEDI_01018 2.5e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NICMNEDI_01019 1.9e-147 yheN G deacetylase
NICMNEDI_01020 1.5e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NICMNEDI_01021 2.6e-226 nhaC C Na H antiporter
NICMNEDI_01022 1.3e-82 nhaX T Belongs to the universal stress protein A family
NICMNEDI_01023 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NICMNEDI_01024 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NICMNEDI_01025 2.6e-109 yheG GM NAD(P)H-binding
NICMNEDI_01026 6.3e-28 sspB S spore protein
NICMNEDI_01027 1.3e-36 yheE S Family of unknown function (DUF5342)
NICMNEDI_01028 1.4e-267 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NICMNEDI_01029 6.2e-215 yheC HJ YheC/D like ATP-grasp
NICMNEDI_01030 2.4e-201 yheB S Belongs to the UPF0754 family
NICMNEDI_01031 9.5e-48 yheA S Belongs to the UPF0342 family
NICMNEDI_01032 1.9e-203 yhaZ L DNA alkylation repair enzyme
NICMNEDI_01033 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NICMNEDI_01034 1.1e-291 hemZ H coproporphyrinogen III oxidase
NICMNEDI_01035 4.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
NICMNEDI_01036 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NICMNEDI_01038 1.1e-130 yhaR 5.3.3.18 I enoyl-CoA hydratase
NICMNEDI_01039 1.6e-25 S YhzD-like protein
NICMNEDI_01040 5.7e-166 yhaQ S ABC transporter, ATP-binding protein
NICMNEDI_01041 2.7e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NICMNEDI_01042 2.8e-224 yhaO L DNA repair exonuclease
NICMNEDI_01043 0.0 yhaN L AAA domain
NICMNEDI_01044 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NICMNEDI_01045 1.6e-21 yhaL S Sporulation protein YhaL
NICMNEDI_01046 2e-115 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NICMNEDI_01047 8.7e-90 yhaK S Putative zincin peptidase
NICMNEDI_01048 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NICMNEDI_01049 1e-113 hpr K Negative regulator of protease production and sporulation
NICMNEDI_01050 8.2e-39 yhaH S YtxH-like protein
NICMNEDI_01051 5.4e-21
NICMNEDI_01052 1.1e-79 trpP S Tryptophan transporter TrpP
NICMNEDI_01053 1.9e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NICMNEDI_01054 6.9e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NICMNEDI_01055 4.6e-137 ecsA V transporter (ATP-binding protein)
NICMNEDI_01056 5.4e-215 ecsB U ABC transporter
NICMNEDI_01057 2e-113 ecsC S EcsC protein family
NICMNEDI_01058 2.8e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NICMNEDI_01059 3.3e-245 yhfA C membrane
NICMNEDI_01060 1.2e-32 1.15.1.2 C Rubrerythrin
NICMNEDI_01061 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NICMNEDI_01062 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NICMNEDI_01063 2.4e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NICMNEDI_01064 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NICMNEDI_01065 7.7e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NICMNEDI_01066 5.4e-101 yhgD K Transcriptional regulator
NICMNEDI_01067 6e-215 yhgE S YhgE Pip N-terminal domain protein
NICMNEDI_01068 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NICMNEDI_01069 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
NICMNEDI_01070 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NICMNEDI_01071 3.7e-72 3.4.13.21 S ASCH
NICMNEDI_01072 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NICMNEDI_01073 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NICMNEDI_01074 6.3e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NICMNEDI_01075 1.4e-110 yhfK GM NmrA-like family
NICMNEDI_01076 2.7e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NICMNEDI_01077 1.2e-241 yhfN 3.4.24.84 O Peptidase M48
NICMNEDI_01078 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NICMNEDI_01079 4.3e-77 VY92_01935 K acetyltransferase
NICMNEDI_01080 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
NICMNEDI_01081 2.8e-158 yfmC M Periplasmic binding protein
NICMNEDI_01082 2.7e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NICMNEDI_01083 2.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
NICMNEDI_01084 3e-273 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NICMNEDI_01085 5e-91 bioY S BioY family
NICMNEDI_01086 4.9e-182 hemAT NT chemotaxis protein
NICMNEDI_01087 1e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NICMNEDI_01088 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NICMNEDI_01089 1.3e-32 yhzC S IDEAL
NICMNEDI_01090 9.3e-109 comK K Competence transcription factor
NICMNEDI_01091 6.2e-168 IQ Enoyl-(Acyl carrier protein) reductase
NICMNEDI_01092 3.9e-41 yhjA S Excalibur calcium-binding domain
NICMNEDI_01093 5.7e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NICMNEDI_01094 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NICMNEDI_01095 8.7e-60 yhjD
NICMNEDI_01096 9.1e-110 yhjE S SNARE associated Golgi protein
NICMNEDI_01097 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NICMNEDI_01098 3.3e-283 yhjG CH FAD binding domain
NICMNEDI_01099 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NICMNEDI_01102 4.2e-212 glcP G Major Facilitator Superfamily
NICMNEDI_01103 1.9e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NICMNEDI_01104 1.3e-159 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NICMNEDI_01105 1.4e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NICMNEDI_01106 1.1e-186 yhjM 5.1.1.1 K Transcriptional regulator
NICMNEDI_01107 9.3e-201 abrB S membrane
NICMNEDI_01108 1e-210 EGP Transmembrane secretion effector
NICMNEDI_01109 0.0 S Sugar transport-related sRNA regulator N-term
NICMNEDI_01110 4.9e-78 yhjR S Rubrerythrin
NICMNEDI_01111 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NICMNEDI_01112 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NICMNEDI_01113 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NICMNEDI_01114 1.4e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NICMNEDI_01115 0.0 sbcC L COG0419 ATPase involved in DNA repair
NICMNEDI_01116 2.1e-48 yisB V COG1403 Restriction endonuclease
NICMNEDI_01117 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NICMNEDI_01118 2.4e-63 gerPE S Spore germination protein GerPE
NICMNEDI_01119 3.1e-23 gerPD S Spore germination protein
NICMNEDI_01120 7e-54 gerPC S Spore germination protein
NICMNEDI_01121 4e-34 gerPB S cell differentiation
NICMNEDI_01122 1.9e-33 gerPA S Spore germination protein
NICMNEDI_01123 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NICMNEDI_01124 4.2e-172 cotH M Spore Coat
NICMNEDI_01125 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NICMNEDI_01126 3e-57 yisL S UPF0344 protein
NICMNEDI_01127 0.0 wprA O Belongs to the peptidase S8 family
NICMNEDI_01128 2.6e-100 yisN S Protein of unknown function (DUF2777)
NICMNEDI_01129 0.0 asnO 6.3.5.4 E Asparagine synthase
NICMNEDI_01130 4.7e-88 yizA S Damage-inducible protein DinB
NICMNEDI_01131 3.8e-145 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NICMNEDI_01132 4e-243 yisQ V Mate efflux family protein
NICMNEDI_01133 1.2e-160 yisR K Transcriptional regulator
NICMNEDI_01134 2.4e-184 purR K helix_turn _helix lactose operon repressor
NICMNEDI_01135 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NICMNEDI_01136 1e-90 yisT S DinB family
NICMNEDI_01137 3.3e-104 argO S Lysine exporter protein LysE YggA
NICMNEDI_01138 1.5e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NICMNEDI_01139 4e-36 mcbG S Pentapeptide repeats (9 copies)
NICMNEDI_01140 2e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NICMNEDI_01141 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NICMNEDI_01142 1.9e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NICMNEDI_01143 2.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NICMNEDI_01144 6.9e-119 comB 3.1.3.71 H Belongs to the ComB family
NICMNEDI_01145 1.6e-140 yitD 4.4.1.19 S synthase
NICMNEDI_01146 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NICMNEDI_01147 1.7e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NICMNEDI_01148 4.3e-98 yitG EGP Major facilitator Superfamily
NICMNEDI_01149 2.1e-98 yitG EGP Major facilitator Superfamily
NICMNEDI_01150 5.3e-153 yitH K Acetyltransferase (GNAT) domain
NICMNEDI_01151 3.2e-72 yjcF S Acetyltransferase (GNAT) domain
NICMNEDI_01152 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NICMNEDI_01153 5.6e-54 yajQ S Belongs to the UPF0234 family
NICMNEDI_01154 1.1e-158 cvfB S protein conserved in bacteria
NICMNEDI_01155 8.5e-94
NICMNEDI_01156 8e-171
NICMNEDI_01157 1.5e-97 S Sporulation delaying protein SdpA
NICMNEDI_01158 1.5e-58 K Transcriptional regulator PadR-like family
NICMNEDI_01159 8e-92
NICMNEDI_01160 1.4e-44 yitR S Domain of unknown function (DUF3784)
NICMNEDI_01161 1.2e-307 nprB 3.4.24.28 E Peptidase M4
NICMNEDI_01162 8.4e-159 yitS S protein conserved in bacteria
NICMNEDI_01163 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NICMNEDI_01164 5e-73 ipi S Intracellular proteinase inhibitor
NICMNEDI_01165 1.2e-17 S Protein of unknown function (DUF3813)
NICMNEDI_01166 1.7e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NICMNEDI_01167 7.6e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NICMNEDI_01168 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NICMNEDI_01169 1.5e-22 pilT S Proteolipid membrane potential modulator
NICMNEDI_01170 1.4e-115 yitY C D-arabinono-1,4-lactone oxidase
NICMNEDI_01171 1.2e-120 yitY C D-arabinono-1,4-lactone oxidase
NICMNEDI_01172 1.7e-88 norB G Major Facilitator Superfamily
NICMNEDI_01173 2.1e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NICMNEDI_01174 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NICMNEDI_01175 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NICMNEDI_01176 6.4e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NICMNEDI_01177 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NICMNEDI_01178 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NICMNEDI_01179 1.8e-39 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NICMNEDI_01180 1e-116 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NICMNEDI_01181 2e-37 yjzC S YjzC-like protein
NICMNEDI_01182 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NICMNEDI_01183 6.2e-142 yjaU I carboxylic ester hydrolase activity
NICMNEDI_01184 4.9e-99 yjaV
NICMNEDI_01185 2.5e-183 med S Transcriptional activator protein med
NICMNEDI_01186 7.3e-26 comZ S ComZ
NICMNEDI_01187 3.9e-10 yjzB
NICMNEDI_01188 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NICMNEDI_01189 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NICMNEDI_01190 3.3e-149 yjaZ O Zn-dependent protease
NICMNEDI_01191 8.8e-184 appD P Belongs to the ABC transporter superfamily
NICMNEDI_01192 1.2e-185 appF E Belongs to the ABC transporter superfamily
NICMNEDI_01193 9.8e-281 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NICMNEDI_01194 2.2e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NICMNEDI_01195 2.7e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NICMNEDI_01196 5e-147 yjbA S Belongs to the UPF0736 family
NICMNEDI_01197 1.4e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NICMNEDI_01198 9.4e-308 oppA E ABC transporter substrate-binding protein
NICMNEDI_01199 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NICMNEDI_01200 1e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NICMNEDI_01201 3.7e-196 oppD P Belongs to the ABC transporter superfamily
NICMNEDI_01202 1.2e-171 oppF E Belongs to the ABC transporter superfamily
NICMNEDI_01203 6.3e-205 yjbB EGP Major Facilitator Superfamily
NICMNEDI_01204 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NICMNEDI_01205 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NICMNEDI_01206 3.9e-111 yjbE P Integral membrane protein TerC family
NICMNEDI_01207 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NICMNEDI_01208 4e-220 yjbF S Competence protein
NICMNEDI_01209 0.0 pepF E oligoendopeptidase F
NICMNEDI_01210 1.8e-20
NICMNEDI_01211 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NICMNEDI_01212 3.7e-72 yjbI S Bacterial-like globin
NICMNEDI_01213 1.5e-95 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NICMNEDI_01214 4.1e-101 yjbK S protein conserved in bacteria
NICMNEDI_01215 2.1e-61 yjbL S Belongs to the UPF0738 family
NICMNEDI_01216 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NICMNEDI_01217 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NICMNEDI_01218 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NICMNEDI_01219 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NICMNEDI_01220 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NICMNEDI_01221 1.3e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NICMNEDI_01222 3.2e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NICMNEDI_01223 1.7e-215 thiO 1.4.3.19 E Glycine oxidase
NICMNEDI_01224 6.7e-30 thiS H thiamine diphosphate biosynthetic process
NICMNEDI_01225 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NICMNEDI_01226 1.8e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NICMNEDI_01227 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NICMNEDI_01228 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NICMNEDI_01229 2.5e-52 yjbX S Spore coat protein
NICMNEDI_01230 5.2e-83 cotZ S Spore coat protein
NICMNEDI_01231 3.4e-96 cotY S Spore coat protein Z
NICMNEDI_01232 1.4e-38 cotX S Spore Coat Protein X and V domain
NICMNEDI_01233 1.4e-10 cotW
NICMNEDI_01234 1.4e-23 cotV S Spore Coat Protein X and V domain
NICMNEDI_01235 1.9e-56 yjcA S Protein of unknown function (DUF1360)
NICMNEDI_01238 2.9e-38 spoVIF S Stage VI sporulation protein F
NICMNEDI_01239 0.0 yjcD 3.6.4.12 L DNA helicase
NICMNEDI_01240 3.8e-38
NICMNEDI_01241 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NICMNEDI_01242 2.4e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NICMNEDI_01243 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
NICMNEDI_01244 1.1e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NICMNEDI_01245 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NICMNEDI_01246 1.2e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
NICMNEDI_01247 2.4e-212 yjcL S Protein of unknown function (DUF819)
NICMNEDI_01249 1.9e-176 L Belongs to the 'phage' integrase family
NICMNEDI_01250 5.5e-09 S Helix-turn-helix domain
NICMNEDI_01251 7.4e-39
NICMNEDI_01254 3.1e-22
NICMNEDI_01255 5.4e-63
NICMNEDI_01257 3.1e-110 L DNA-dependent DNA replication
NICMNEDI_01258 1.4e-12 yodN
NICMNEDI_01259 1.1e-10 S YopX protein
NICMNEDI_01261 2.3e-145 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
NICMNEDI_01262 3.3e-133 dnaG L Toprim-like
NICMNEDI_01264 2.8e-43
NICMNEDI_01270 8.9e-46
NICMNEDI_01271 6.3e-49
NICMNEDI_01272 3e-27
NICMNEDI_01273 1.3e-195 L DNA polymerase A domain
NICMNEDI_01275 9.5e-168
NICMNEDI_01277 1.1e-32 ruvC 3.1.22.4 L Crossover junction endodeoxyribonuclease RuvC
NICMNEDI_01283 4.8e-37 nrdI 1.17.4.1 F Belongs to the NrdI family
NICMNEDI_01284 1.5e-111 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NICMNEDI_01285 1.7e-45 S HNH endonuclease
NICMNEDI_01286 4e-205 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NICMNEDI_01288 3e-152 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NICMNEDI_01290 7.6e-57 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
NICMNEDI_01291 2.6e-112 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NICMNEDI_01292 3e-37 S protein conserved in bacteria
NICMNEDI_01294 1.1e-34
NICMNEDI_01295 3.7e-73 2.7.1.24 H dephospho-CoA kinase activity
NICMNEDI_01297 2.6e-43 K Sigma-70, region 4
NICMNEDI_01298 8.2e-34
NICMNEDI_01299 4.3e-12
NICMNEDI_01300 1.6e-25 S Helix-turn-helix domain
NICMNEDI_01301 1.9e-123 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
NICMNEDI_01303 1.2e-22
NICMNEDI_01304 5.3e-48
NICMNEDI_01307 2.2e-113 3.2.1.15 M Right handed beta helix region
NICMNEDI_01308 4.3e-56 S Pfam:DUF867
NICMNEDI_01309 4.5e-27 K Cro/C1-type HTH DNA-binding domain
NICMNEDI_01310 2.9e-44 M Glycosyltransferase like family 2
NICMNEDI_01316 3.8e-79
NICMNEDI_01318 4.7e-31 L HNH endonuclease
NICMNEDI_01319 5.1e-48 L Phage terminase, small subunit
NICMNEDI_01320 3.8e-294 S Terminase
NICMNEDI_01321 2.8e-222 S Phage portal protein
NICMNEDI_01322 6.6e-115 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NICMNEDI_01323 2.5e-158 S Phage capsid family
NICMNEDI_01324 1.4e-28 N domain, Protein
NICMNEDI_01325 7e-26 S Phage gp6-like head-tail connector protein
NICMNEDI_01326 9.9e-34 S Phage head-tail joining protein
NICMNEDI_01328 2.2e-25
NICMNEDI_01329 5.5e-72 N phage major tail protein, phi13 family
NICMNEDI_01330 1.1e-32
NICMNEDI_01331 1.5e-128 D Phage tail tape measure protein
NICMNEDI_01332 3.9e-68 S Phage tail protein
NICMNEDI_01333 1.6e-73 lyc 3.2.1.17 M Glycosyl hydrolases family 25
NICMNEDI_01334 9.8e-43
NICMNEDI_01337 1.1e-29 S Haemolysin XhlA
NICMNEDI_01338 5.7e-148 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
NICMNEDI_01339 6.3e-33 S Bacteriophage A118-like holin, Hol118
NICMNEDI_01341 8.8e-19 S YolD-like protein
NICMNEDI_01342 4.8e-21 S protein disulfide oxidoreductase activity
NICMNEDI_01344 7.2e-129 ftsK D FtsK/SpoIIIE family
NICMNEDI_01345 2.6e-64
NICMNEDI_01347 1.3e-15 K Transcriptional regulator
NICMNEDI_01348 9.9e-101 K Helix-turn-helix domain
NICMNEDI_01349 5.2e-18
NICMNEDI_01350 1.6e-38
NICMNEDI_01351 1e-29
NICMNEDI_01352 5.2e-235 M nucleic acid phosphodiester bond hydrolysis
NICMNEDI_01353 8.3e-21
NICMNEDI_01356 2e-179 S response regulator aspartate phosphatase
NICMNEDI_01357 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
NICMNEDI_01358 1e-45 yjcN
NICMNEDI_01359 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NICMNEDI_01360 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NICMNEDI_01361 1.6e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
NICMNEDI_01362 2.5e-47 yjdF S Protein of unknown function (DUF2992)
NICMNEDI_01363 3.4e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NICMNEDI_01365 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NICMNEDI_01366 4.2e-29 S Domain of unknown function (DUF4177)
NICMNEDI_01367 3.5e-52 yjdJ S Domain of unknown function (DUF4306)
NICMNEDI_01368 1.4e-167 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NICMNEDI_01370 3.2e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
NICMNEDI_01371 5.5e-83 S Protein of unknown function (DUF2690)
NICMNEDI_01372 2.3e-20 yjfB S Putative motility protein
NICMNEDI_01373 1.5e-112 yjfC O Predicted Zn-dependent protease (DUF2268)
NICMNEDI_01374 9e-33 yjfC O Predicted Zn-dependent protease (DUF2268)
NICMNEDI_01375 2.7e-45 T PhoQ Sensor
NICMNEDI_01376 2e-103 yjgB S Domain of unknown function (DUF4309)
NICMNEDI_01377 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NICMNEDI_01378 1.6e-94 yjgD S Protein of unknown function (DUF1641)
NICMNEDI_01380 1.5e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NICMNEDI_01382 1.1e-220 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NICMNEDI_01383 7.7e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NICMNEDI_01384 1.4e-29
NICMNEDI_01385 3.9e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NICMNEDI_01386 2.5e-122 ybbM S transport system, permease component
NICMNEDI_01387 2.2e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NICMNEDI_01388 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
NICMNEDI_01389 3.4e-91 yjlB S Cupin domain
NICMNEDI_01390 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NICMNEDI_01391 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NICMNEDI_01392 2.5e-277 uxaC 5.3.1.12 G glucuronate isomerase
NICMNEDI_01393 1.3e-246 yjmB G symporter YjmB
NICMNEDI_01394 2.5e-134 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NICMNEDI_01395 7.7e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NICMNEDI_01396 1.3e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NICMNEDI_01397 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_01398 2.4e-226 exuT G Sugar (and other) transporter
NICMNEDI_01399 5.2e-184 exuR K transcriptional
NICMNEDI_01400 2.7e-282 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NICMNEDI_01401 1.1e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NICMNEDI_01402 7.4e-130 MA20_18170 S membrane transporter protein
NICMNEDI_01403 2.3e-78 yjoA S DinB family
NICMNEDI_01404 2.1e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NICMNEDI_01405 1e-212 S response regulator aspartate phosphatase
NICMNEDI_01407 6.3e-41 S YCII-related domain
NICMNEDI_01408 3.3e-164 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NICMNEDI_01409 5.2e-60 yjqA S Bacterial PH domain
NICMNEDI_01410 3.3e-109 yjqB S Pfam:DUF867
NICMNEDI_01411 4.4e-160 ydbD P Catalase
NICMNEDI_01412 1.6e-111 xkdA E IrrE N-terminal-like domain
NICMNEDI_01413 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NICMNEDI_01415 5.9e-157 xkdB K sequence-specific DNA binding
NICMNEDI_01416 6.4e-119 xkdC L Bacterial dnaA protein
NICMNEDI_01419 2.3e-09 yqaO S Phage-like element PBSX protein XtrA
NICMNEDI_01420 1.6e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NICMNEDI_01421 1.2e-138 xtmA L phage terminase small subunit
NICMNEDI_01422 1.2e-252 xtmB S phage terminase, large subunit
NICMNEDI_01423 1.6e-285 yqbA S portal protein
NICMNEDI_01424 2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NICMNEDI_01425 5.8e-169 xkdG S Phage capsid family
NICMNEDI_01426 5.1e-63 yqbG S Protein of unknown function (DUF3199)
NICMNEDI_01427 2.5e-64 yqbH S Domain of unknown function (DUF3599)
NICMNEDI_01428 1.9e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
NICMNEDI_01429 1.9e-77 xkdJ
NICMNEDI_01430 2.5e-256 xkdK S Phage tail sheath C-terminal domain
NICMNEDI_01431 6.1e-76 xkdM S Phage tail tube protein
NICMNEDI_01432 2.3e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
NICMNEDI_01433 0.0 xkdO L Transglycosylase SLT domain
NICMNEDI_01434 2.7e-120 xkdP S Lysin motif
NICMNEDI_01435 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NICMNEDI_01436 3e-38 xkdR S Protein of unknown function (DUF2577)
NICMNEDI_01437 3.1e-69 xkdS S Protein of unknown function (DUF2634)
NICMNEDI_01438 2.8e-188 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NICMNEDI_01439 4.9e-102 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NICMNEDI_01440 6.7e-41
NICMNEDI_01441 1.3e-184
NICMNEDI_01442 1.6e-52 xkdW S XkdW protein
NICMNEDI_01443 5.5e-22 xkdX
NICMNEDI_01444 2.8e-154 xepA
NICMNEDI_01445 2.8e-39 xhlA S Haemolysin XhlA
NICMNEDI_01446 9.3e-40 xhlB S SPP1 phage holin
NICMNEDI_01447 3.9e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NICMNEDI_01448 2.5e-62 G Acyltransferase family
NICMNEDI_01449 6.7e-23 spoIISB S Stage II sporulation protein SB
NICMNEDI_01450 1.1e-135 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NICMNEDI_01451 9.9e-175 pit P phosphate transporter
NICMNEDI_01452 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NICMNEDI_01453 1.2e-239 steT E amino acid
NICMNEDI_01454 8.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NICMNEDI_01456 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NICMNEDI_01457 3.8e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NICMNEDI_01459 6.8e-211 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NICMNEDI_01460 2.1e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NICMNEDI_01461 5.1e-153 dppA E D-aminopeptidase
NICMNEDI_01462 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NICMNEDI_01463 1.3e-174 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NICMNEDI_01464 2.4e-189 dppD P Belongs to the ABC transporter superfamily
NICMNEDI_01465 0.0 dppE E ABC transporter substrate-binding protein
NICMNEDI_01467 2.1e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NICMNEDI_01468 1.8e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NICMNEDI_01469 1.8e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NICMNEDI_01470 7.2e-186 ykfD E Belongs to the ABC transporter superfamily
NICMNEDI_01471 1.8e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
NICMNEDI_01472 2.7e-160 ykgA E Amidinotransferase
NICMNEDI_01473 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NICMNEDI_01474 3.9e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NICMNEDI_01475 1e-10
NICMNEDI_01476 2.7e-129 ykjA S Protein of unknown function (DUF421)
NICMNEDI_01477 8.8e-98 ykkA S Protein of unknown function (DUF664)
NICMNEDI_01478 1.1e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NICMNEDI_01479 3.5e-55 ykkC P Multidrug resistance protein
NICMNEDI_01480 7e-50 ykkD P Multidrug resistance protein
NICMNEDI_01481 1.1e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NICMNEDI_01482 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NICMNEDI_01483 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NICMNEDI_01484 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NICMNEDI_01485 9.7e-74 ohrR K COG1846 Transcriptional regulators
NICMNEDI_01486 8.4e-72 ohrB O Organic hydroperoxide resistance protein
NICMNEDI_01487 3.1e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NICMNEDI_01488 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NICMNEDI_01489 1.7e-176 isp O Belongs to the peptidase S8 family
NICMNEDI_01490 9.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NICMNEDI_01491 1.7e-134 ykoC P Cobalt transport protein
NICMNEDI_01492 3.2e-308 P ABC transporter, ATP-binding protein
NICMNEDI_01493 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
NICMNEDI_01494 1.1e-109 ykoF S YKOF-related Family
NICMNEDI_01495 4.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_01496 1e-243 ykoH 2.7.13.3 T Histidine kinase
NICMNEDI_01497 6.2e-112 ykoI S Peptidase propeptide and YPEB domain
NICMNEDI_01498 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
NICMNEDI_01501 2.2e-222 mgtE P Acts as a magnesium transporter
NICMNEDI_01502 1.4e-53 tnrA K transcriptional
NICMNEDI_01503 5.9e-18
NICMNEDI_01504 6.9e-26 ykoL
NICMNEDI_01505 1.3e-81 mhqR K transcriptional
NICMNEDI_01506 3.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NICMNEDI_01507 2.7e-97 ykoP G polysaccharide deacetylase
NICMNEDI_01508 1e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NICMNEDI_01509 0.0 ykoS
NICMNEDI_01510 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NICMNEDI_01511 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NICMNEDI_01512 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NICMNEDI_01513 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NICMNEDI_01514 3.5e-109 ykoX S membrane-associated protein
NICMNEDI_01515 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NICMNEDI_01516 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NICMNEDI_01517 2.1e-112 rsgI S Anti-sigma factor N-terminus
NICMNEDI_01518 1.9e-26 sspD S small acid-soluble spore protein
NICMNEDI_01519 1.5e-124 ykrK S Domain of unknown function (DUF1836)
NICMNEDI_01520 3.5e-155 htpX O Belongs to the peptidase M48B family
NICMNEDI_01521 4.8e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NICMNEDI_01522 1.2e-10 ydfR S Protein of unknown function (DUF421)
NICMNEDI_01523 4.1e-18 ykzE
NICMNEDI_01524 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NICMNEDI_01525 0.0 kinE 2.7.13.3 T Histidine kinase
NICMNEDI_01526 5.9e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NICMNEDI_01528 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NICMNEDI_01529 1.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NICMNEDI_01530 2.9e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NICMNEDI_01531 1.8e-231 mtnE 2.6.1.83 E Aminotransferase
NICMNEDI_01532 1.2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NICMNEDI_01533 2.9e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NICMNEDI_01534 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NICMNEDI_01535 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NICMNEDI_01536 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
NICMNEDI_01537 6.4e-09 S Spo0E like sporulation regulatory protein
NICMNEDI_01538 9.7e-53 eag
NICMNEDI_01539 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NICMNEDI_01540 1.3e-75 ykvE K transcriptional
NICMNEDI_01541 2.5e-125 motB N Flagellar motor protein
NICMNEDI_01542 2.7e-138 motA N flagellar motor
NICMNEDI_01543 0.0 clpE O Belongs to the ClpA ClpB family
NICMNEDI_01544 1.5e-178 ykvI S membrane
NICMNEDI_01545 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NICMNEDI_01546 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NICMNEDI_01547 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NICMNEDI_01548 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NICMNEDI_01549 2.9e-60 ykvN K Transcriptional regulator
NICMNEDI_01550 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
NICMNEDI_01551 4.9e-215 ykvP 3.5.1.28 M Glycosyl transferases group 1
NICMNEDI_01552 3.5e-35 3.5.1.104 M LysM domain
NICMNEDI_01553 2e-161 G Glycosyl hydrolases family 18
NICMNEDI_01554 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NICMNEDI_01555 6e-25 ykvS S protein conserved in bacteria
NICMNEDI_01556 2.7e-28
NICMNEDI_01557 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NICMNEDI_01558 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NICMNEDI_01559 9.2e-89 stoA CO thiol-disulfide
NICMNEDI_01560 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NICMNEDI_01561 2.3e-09
NICMNEDI_01562 6.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NICMNEDI_01564 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
NICMNEDI_01566 7.6e-128 glcT K antiterminator
NICMNEDI_01567 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NICMNEDI_01568 2.1e-39 ptsH G phosphocarrier protein HPr
NICMNEDI_01569 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NICMNEDI_01570 7.2e-39 splA S Transcriptional regulator
NICMNEDI_01571 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
NICMNEDI_01572 1.7e-125 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NICMNEDI_01573 1.3e-258 mcpC NT chemotaxis protein
NICMNEDI_01574 9.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NICMNEDI_01575 3.5e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
NICMNEDI_01576 2.4e-120 ykwD J protein with SCP PR1 domains
NICMNEDI_01577 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NICMNEDI_01578 0.0 pilS 2.7.13.3 T Histidine kinase
NICMNEDI_01579 1.5e-222 patA 2.6.1.1 E Aminotransferase
NICMNEDI_01580 1.3e-15
NICMNEDI_01581 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NICMNEDI_01582 1.7e-84 ykyB S YkyB-like protein
NICMNEDI_01583 2.8e-238 ykuC EGP Major facilitator Superfamily
NICMNEDI_01584 1.8e-87 ykuD S protein conserved in bacteria
NICMNEDI_01585 9.4e-166 ykuE S Metallophosphoesterase
NICMNEDI_01586 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NICMNEDI_01587 5.2e-234 ykuI T Diguanylate phosphodiesterase
NICMNEDI_01588 3.9e-37 ykuJ S protein conserved in bacteria
NICMNEDI_01589 2.2e-93 ykuK S Ribonuclease H-like
NICMNEDI_01590 3.9e-27 ykzF S Antirepressor AbbA
NICMNEDI_01591 1.6e-76 ykuL S CBS domain
NICMNEDI_01592 3.5e-168 ccpC K Transcriptional regulator
NICMNEDI_01593 2.9e-84 fld C Flavodoxin domain
NICMNEDI_01594 9.7e-174 ykuO
NICMNEDI_01595 6.7e-78 fld C Flavodoxin
NICMNEDI_01596 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NICMNEDI_01597 7.1e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NICMNEDI_01598 9e-37 ykuS S Belongs to the UPF0180 family
NICMNEDI_01599 8.8e-142 ykuT M Mechanosensitive ion channel
NICMNEDI_01600 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NICMNEDI_01601 4.1e-80 ykuV CO thiol-disulfide
NICMNEDI_01602 1.5e-93 rok K Repressor of ComK
NICMNEDI_01603 2.1e-145 yknT
NICMNEDI_01604 1.6e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NICMNEDI_01605 2e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NICMNEDI_01606 2.9e-243 moeA 2.10.1.1 H molybdopterin
NICMNEDI_01607 1.1e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NICMNEDI_01608 2.1e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NICMNEDI_01609 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NICMNEDI_01610 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NICMNEDI_01611 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NICMNEDI_01612 1.4e-114 yknW S Yip1 domain
NICMNEDI_01613 2.5e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NICMNEDI_01614 5.5e-124 macB V ABC transporter, ATP-binding protein
NICMNEDI_01615 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NICMNEDI_01616 3.1e-136 fruR K Transcriptional regulator
NICMNEDI_01617 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NICMNEDI_01618 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NICMNEDI_01619 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NICMNEDI_01620 8.1e-39 ykoA
NICMNEDI_01621 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NICMNEDI_01622 7.4e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NICMNEDI_01623 5.9e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NICMNEDI_01624 1.1e-12 S Uncharacterized protein YkpC
NICMNEDI_01625 7.7e-183 mreB D Rod-share determining protein MreBH
NICMNEDI_01626 1.5e-43 abrB K of stationary sporulation gene expression
NICMNEDI_01627 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NICMNEDI_01628 6.5e-156 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NICMNEDI_01629 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NICMNEDI_01630 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NICMNEDI_01631 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NICMNEDI_01632 8.2e-31 ykzG S Belongs to the UPF0356 family
NICMNEDI_01633 4.2e-147 ykrA S hydrolases of the HAD superfamily
NICMNEDI_01634 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NICMNEDI_01636 7.7e-115 recN L Putative cell-wall binding lipoprotein
NICMNEDI_01637 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NICMNEDI_01638 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NICMNEDI_01639 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NICMNEDI_01640 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NICMNEDI_01641 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NICMNEDI_01642 1e-276 speA 4.1.1.19 E Arginine
NICMNEDI_01643 1.7e-41 yktA S Belongs to the UPF0223 family
NICMNEDI_01644 4.6e-117 yktB S Belongs to the UPF0637 family
NICMNEDI_01645 7.1e-26 ykzI
NICMNEDI_01646 1.7e-148 suhB 3.1.3.25 G Inositol monophosphatase
NICMNEDI_01647 1.7e-76 ykzC S Acetyltransferase (GNAT) family
NICMNEDI_01648 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NICMNEDI_01649 3.7e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NICMNEDI_01650 0.0 ylaA
NICMNEDI_01651 2.7e-42 ylaB
NICMNEDI_01652 3.3e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NICMNEDI_01653 1.2e-11 sigC S Putative zinc-finger
NICMNEDI_01654 2.6e-37 ylaE
NICMNEDI_01655 8.2e-22 S Family of unknown function (DUF5325)
NICMNEDI_01656 0.0 typA T GTP-binding protein TypA
NICMNEDI_01657 4.2e-47 ylaH S YlaH-like protein
NICMNEDI_01658 5.6e-32 ylaI S protein conserved in bacteria
NICMNEDI_01659 1.2e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NICMNEDI_01660 2.3e-248 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NICMNEDI_01661 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NICMNEDI_01662 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NICMNEDI_01663 8.7e-44 ylaN S Belongs to the UPF0358 family
NICMNEDI_01664 2.5e-212 ftsW D Belongs to the SEDS family
NICMNEDI_01665 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NICMNEDI_01666 8.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NICMNEDI_01667 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NICMNEDI_01668 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NICMNEDI_01669 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NICMNEDI_01670 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NICMNEDI_01671 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NICMNEDI_01672 1.5e-166 ctaG S cytochrome c oxidase
NICMNEDI_01673 7.7e-61 ylbA S YugN-like family
NICMNEDI_01674 2.6e-74 ylbB T COG0517 FOG CBS domain
NICMNEDI_01675 9.6e-200 ylbC S protein with SCP PR1 domains
NICMNEDI_01676 1.4e-60 ylbD S Putative coat protein
NICMNEDI_01677 6.7e-37 ylbE S YlbE-like protein
NICMNEDI_01678 1.8e-75 ylbF S Belongs to the UPF0342 family
NICMNEDI_01679 3.7e-38 ylbG S UPF0298 protein
NICMNEDI_01680 3e-96 rsmD 2.1.1.171 L Methyltransferase
NICMNEDI_01681 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NICMNEDI_01682 3.6e-219 ylbJ S Sporulation integral membrane protein YlbJ
NICMNEDI_01683 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
NICMNEDI_01684 6.8e-187 ylbL T Belongs to the peptidase S16 family
NICMNEDI_01685 3e-229 ylbM S Belongs to the UPF0348 family
NICMNEDI_01687 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NICMNEDI_01688 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NICMNEDI_01689 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NICMNEDI_01690 1.5e-88 ylbP K n-acetyltransferase
NICMNEDI_01691 2.8e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NICMNEDI_01692 6e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NICMNEDI_01693 2.9e-78 mraZ K Belongs to the MraZ family
NICMNEDI_01694 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NICMNEDI_01695 3.7e-44 ftsL D Essential cell division protein
NICMNEDI_01696 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NICMNEDI_01697 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NICMNEDI_01698 2e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NICMNEDI_01699 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NICMNEDI_01700 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NICMNEDI_01701 9.5e-80 spoVE D Belongs to the SEDS family
NICMNEDI_01702 8.2e-97 spoVE D Belongs to the SEDS family
NICMNEDI_01703 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NICMNEDI_01704 9e-167 murB 1.3.1.98 M cell wall formation
NICMNEDI_01705 7.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NICMNEDI_01706 2.4e-103 ylxW S protein conserved in bacteria
NICMNEDI_01707 1.3e-102 ylxX S protein conserved in bacteria
NICMNEDI_01708 6.2e-58 sbp S small basic protein
NICMNEDI_01709 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NICMNEDI_01710 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NICMNEDI_01711 0.0 bpr O COG1404 Subtilisin-like serine proteases
NICMNEDI_01712 1.4e-170 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NICMNEDI_01713 3e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NICMNEDI_01714 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NICMNEDI_01715 5.3e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NICMNEDI_01716 2e-252 argE 3.5.1.16 E Acetylornithine deacetylase
NICMNEDI_01717 2.4e-37 ylmC S sporulation protein
NICMNEDI_01718 7e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NICMNEDI_01719 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NICMNEDI_01720 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NICMNEDI_01721 1.3e-39 yggT S membrane
NICMNEDI_01722 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NICMNEDI_01723 2.6e-67 divIVA D Cell division initiation protein
NICMNEDI_01724 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NICMNEDI_01725 8.5e-63 dksA T COG1734 DnaK suppressor protein
NICMNEDI_01726 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NICMNEDI_01727 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NICMNEDI_01728 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NICMNEDI_01729 2.6e-231 pyrP F Xanthine uracil
NICMNEDI_01730 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NICMNEDI_01731 6.4e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NICMNEDI_01732 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NICMNEDI_01733 0.0 carB 6.3.5.5 F Belongs to the CarB family
NICMNEDI_01734 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NICMNEDI_01735 1.7e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NICMNEDI_01736 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NICMNEDI_01737 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NICMNEDI_01738 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NICMNEDI_01739 1.8e-179 cysP P phosphate transporter
NICMNEDI_01740 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NICMNEDI_01741 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NICMNEDI_01742 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NICMNEDI_01743 1.2e-143 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NICMNEDI_01744 3.7e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NICMNEDI_01745 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NICMNEDI_01746 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NICMNEDI_01747 2.4e-156 yloC S stress-induced protein
NICMNEDI_01748 1.5e-40 ylzA S Belongs to the UPF0296 family
NICMNEDI_01749 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NICMNEDI_01750 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NICMNEDI_01751 7e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NICMNEDI_01752 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NICMNEDI_01753 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NICMNEDI_01754 4.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NICMNEDI_01755 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NICMNEDI_01756 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NICMNEDI_01757 1.6e-140 stp 3.1.3.16 T phosphatase
NICMNEDI_01758 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NICMNEDI_01759 1.9e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NICMNEDI_01760 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NICMNEDI_01761 4.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
NICMNEDI_01762 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NICMNEDI_01763 5.5e-59 asp S protein conserved in bacteria
NICMNEDI_01764 1.7e-301 yloV S kinase related to dihydroxyacetone kinase
NICMNEDI_01765 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NICMNEDI_01766 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NICMNEDI_01767 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NICMNEDI_01768 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NICMNEDI_01769 2.1e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NICMNEDI_01770 1.2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NICMNEDI_01771 3e-128 IQ reductase
NICMNEDI_01772 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NICMNEDI_01773 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NICMNEDI_01774 0.0 smc D Required for chromosome condensation and partitioning
NICMNEDI_01775 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NICMNEDI_01776 2.9e-87
NICMNEDI_01777 2.1e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NICMNEDI_01778 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NICMNEDI_01779 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NICMNEDI_01780 4.5e-36 ylqC S Belongs to the UPF0109 family
NICMNEDI_01781 6.3e-61 ylqD S YlqD protein
NICMNEDI_01782 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NICMNEDI_01783 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NICMNEDI_01784 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NICMNEDI_01785 5.1e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NICMNEDI_01786 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NICMNEDI_01787 9.1e-285 ylqG
NICMNEDI_01788 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NICMNEDI_01789 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NICMNEDI_01790 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NICMNEDI_01791 4.7e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NICMNEDI_01792 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NICMNEDI_01793 2.6e-43 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NICMNEDI_01794 3.4e-194 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NICMNEDI_01795 2.5e-169 xerC L tyrosine recombinase XerC
NICMNEDI_01796 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NICMNEDI_01797 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NICMNEDI_01798 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NICMNEDI_01799 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NICMNEDI_01800 4.9e-73 flgC N Belongs to the flagella basal body rod proteins family
NICMNEDI_01801 1.9e-31 fliE N Flagellar hook-basal body
NICMNEDI_01802 1e-250 fliF N The M ring may be actively involved in energy transduction
NICMNEDI_01803 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NICMNEDI_01804 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NICMNEDI_01805 3.6e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NICMNEDI_01806 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NICMNEDI_01807 5.5e-35 ylxF S MgtE intracellular N domain
NICMNEDI_01808 1.1e-214 fliK N Flagellar hook-length control protein
NICMNEDI_01809 1.7e-72 flgD N Flagellar basal body rod modification protein
NICMNEDI_01810 8.2e-140 flgG N Flagellar basal body rod
NICMNEDI_01811 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NICMNEDI_01812 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NICMNEDI_01813 1.1e-174 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NICMNEDI_01814 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NICMNEDI_01815 6e-96 fliZ N Flagellar biosynthesis protein, FliO
NICMNEDI_01816 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NICMNEDI_01817 2.2e-36 fliQ N Role in flagellar biosynthesis
NICMNEDI_01818 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NICMNEDI_01819 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NICMNEDI_01820 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NICMNEDI_01821 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
NICMNEDI_01822 2.8e-157 flhG D Belongs to the ParA family
NICMNEDI_01823 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NICMNEDI_01824 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NICMNEDI_01825 2.4e-78 cheW NT COG0835 Chemotaxis signal transduction protein
NICMNEDI_01826 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NICMNEDI_01827 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NICMNEDI_01828 7.4e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NICMNEDI_01829 3.1e-76 ylxL
NICMNEDI_01830 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NICMNEDI_01831 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NICMNEDI_01832 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NICMNEDI_01833 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NICMNEDI_01834 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NICMNEDI_01835 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NICMNEDI_01836 1e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NICMNEDI_01837 2.2e-232 rasP M zinc metalloprotease
NICMNEDI_01838 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NICMNEDI_01839 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NICMNEDI_01840 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NICMNEDI_01841 1.1e-203 nusA K Participates in both transcription termination and antitermination
NICMNEDI_01842 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NICMNEDI_01843 3.1e-47 ylxQ J ribosomal protein
NICMNEDI_01844 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NICMNEDI_01845 3.9e-44 ylxP S protein conserved in bacteria
NICMNEDI_01846 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NICMNEDI_01847 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NICMNEDI_01848 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NICMNEDI_01849 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NICMNEDI_01850 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NICMNEDI_01851 3.6e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NICMNEDI_01852 2.2e-232 pepR S Belongs to the peptidase M16 family
NICMNEDI_01853 2.6e-42 ymxH S YlmC YmxH family
NICMNEDI_01854 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NICMNEDI_01855 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NICMNEDI_01856 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NICMNEDI_01857 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NICMNEDI_01858 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NICMNEDI_01859 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NICMNEDI_01860 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NICMNEDI_01861 4.4e-32 S YlzJ-like protein
NICMNEDI_01862 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NICMNEDI_01863 1.4e-133 ymfC K Transcriptional regulator
NICMNEDI_01864 8.5e-205 ymfD EGP Major facilitator Superfamily
NICMNEDI_01865 3e-232 ymfF S Peptidase M16
NICMNEDI_01866 1.4e-242 ymfH S zinc protease
NICMNEDI_01867 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NICMNEDI_01868 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NICMNEDI_01869 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NICMNEDI_01870 1.9e-124 ymfM S protein conserved in bacteria
NICMNEDI_01871 5.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NICMNEDI_01872 2.1e-235 cinA 3.5.1.42 S Belongs to the CinA family
NICMNEDI_01873 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NICMNEDI_01874 9.1e-212 pbpX V Beta-lactamase
NICMNEDI_01875 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NICMNEDI_01876 1.9e-152 ymdB S protein conserved in bacteria
NICMNEDI_01877 1.2e-36 spoVS S Stage V sporulation protein S
NICMNEDI_01878 2.1e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NICMNEDI_01879 1.2e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NICMNEDI_01880 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NICMNEDI_01881 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NICMNEDI_01882 2.2e-88 cotE S Spore coat protein
NICMNEDI_01883 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NICMNEDI_01884 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NICMNEDI_01885 8.9e-70 S Regulatory protein YrvL
NICMNEDI_01887 6e-97 ymcC S Membrane
NICMNEDI_01888 2.4e-107 pksA K Transcriptional regulator
NICMNEDI_01889 5.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
NICMNEDI_01890 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NICMNEDI_01892 2.5e-183 pksD Q Acyl transferase domain
NICMNEDI_01893 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NICMNEDI_01894 1.4e-37 acpK IQ Phosphopantetheine attachment site
NICMNEDI_01895 3.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NICMNEDI_01896 8.7e-245 pksG 2.3.3.10 I synthase
NICMNEDI_01897 4.2e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
NICMNEDI_01898 2e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NICMNEDI_01899 0.0 rhiB IQ polyketide synthase
NICMNEDI_01900 0.0 pfaA Q Polyketide synthase of type I
NICMNEDI_01901 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NICMNEDI_01902 0.0 dhbF IQ polyketide synthase
NICMNEDI_01903 0.0 pks13 HQ Beta-ketoacyl synthase
NICMNEDI_01904 1.5e-230 cypA C Cytochrome P450
NICMNEDI_01905 4.4e-61 ymzB
NICMNEDI_01906 1.2e-160 ymaE S Metallo-beta-lactamase superfamily
NICMNEDI_01907 3e-251 aprX O Belongs to the peptidase S8 family
NICMNEDI_01908 1.9e-07 K Transcriptional regulator
NICMNEDI_01909 2.1e-126 ymaC S Replication protein
NICMNEDI_01910 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
NICMNEDI_01911 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NICMNEDI_01912 5.4e-50 ebrA P Small Multidrug Resistance protein
NICMNEDI_01914 2.1e-46 ymaF S YmaF family
NICMNEDI_01915 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NICMNEDI_01916 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NICMNEDI_01917 8.2e-23
NICMNEDI_01918 4.5e-22 ymzA
NICMNEDI_01919 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NICMNEDI_01920 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NICMNEDI_01921 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NICMNEDI_01922 2e-109 ymaB
NICMNEDI_01923 7.5e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NICMNEDI_01924 1.7e-176 spoVK O stage V sporulation protein K
NICMNEDI_01925 2.3e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NICMNEDI_01926 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NICMNEDI_01927 1.1e-68 glnR K transcriptional
NICMNEDI_01928 7e-261 glnA 6.3.1.2 E glutamine synthetase
NICMNEDI_01930 2.3e-10
NICMNEDI_01931 7.3e-30
NICMNEDI_01932 1e-124
NICMNEDI_01933 2.1e-36
NICMNEDI_01934 1.7e-93 G SMI1-KNR4 cell-wall
NICMNEDI_01935 3.6e-96 ynaD J Acetyltransferase (GNAT) domain
NICMNEDI_01936 1.3e-119 ynaE S Domain of unknown function (DUF3885)
NICMNEDI_01937 7.1e-34 ynaF
NICMNEDI_01939 1.1e-253 xynT G MFS/sugar transport protein
NICMNEDI_01940 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NICMNEDI_01941 7.3e-214 xylR GK ROK family
NICMNEDI_01942 1.3e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NICMNEDI_01943 4.3e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NICMNEDI_01944 4.1e-110 yokF 3.1.31.1 L RNA catabolic process
NICMNEDI_01945 2.7e-255 iolT EGP Major facilitator Superfamily
NICMNEDI_01946 3.8e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NICMNEDI_01947 1e-81 yncE S Protein of unknown function (DUF2691)
NICMNEDI_01948 4.1e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NICMNEDI_01951 6.6e-164 S Thymidylate synthase
NICMNEDI_01953 5.4e-47 S Domain of unknown function, YrpD
NICMNEDI_01954 9.1e-59 S Domain of unknown function, YrpD
NICMNEDI_01957 7.9e-25 tatA U protein secretion
NICMNEDI_01958 1.2e-70
NICMNEDI_01959 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NICMNEDI_01962 4.8e-285 gerAA EG Spore germination protein
NICMNEDI_01963 6.1e-194 gerAB U Spore germination
NICMNEDI_01964 2.2e-216 gerLC S Spore germination protein
NICMNEDI_01965 6.8e-150 yndG S DoxX-like family
NICMNEDI_01966 7.8e-114 yndH S Domain of unknown function (DUF4166)
NICMNEDI_01967 7.3e-284 yndJ S YndJ-like protein
NICMNEDI_01969 4.2e-133 yndL S Replication protein
NICMNEDI_01970 5.8e-74 yndM S Protein of unknown function (DUF2512)
NICMNEDI_01971 4.1e-77 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NICMNEDI_01972 4.3e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NICMNEDI_01973 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NICMNEDI_01974 9.2e-113 yneB L resolvase
NICMNEDI_01975 1.3e-32 ynzC S UPF0291 protein
NICMNEDI_01976 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NICMNEDI_01977 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NICMNEDI_01978 1.8e-28 yneF S UPF0154 protein
NICMNEDI_01979 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NICMNEDI_01980 7.1e-127 ccdA O cytochrome c biogenesis protein
NICMNEDI_01981 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NICMNEDI_01982 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NICMNEDI_01983 4.2e-74 yneK S Protein of unknown function (DUF2621)
NICMNEDI_01984 1.7e-63 hspX O Spore coat protein
NICMNEDI_01985 3.9e-19 sspP S Belongs to the SspP family
NICMNEDI_01986 2.5e-14 sspO S Belongs to the SspO family
NICMNEDI_01987 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NICMNEDI_01988 2.9e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NICMNEDI_01990 3.1e-08 sspN S Small acid-soluble spore protein N family
NICMNEDI_01991 3.9e-35 tlp S Belongs to the Tlp family
NICMNEDI_01992 1.2e-73 yneP S Thioesterase-like superfamily
NICMNEDI_01993 2.2e-53 yneQ
NICMNEDI_01994 4.1e-49 yneR S Belongs to the HesB IscA family
NICMNEDI_01995 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NICMNEDI_01996 6.6e-69 yccU S CoA-binding protein
NICMNEDI_01997 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NICMNEDI_01998 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NICMNEDI_01999 2.3e-11
NICMNEDI_02000 8.6e-57 ynfC
NICMNEDI_02001 1.8e-251 agcS E Sodium alanine symporter
NICMNEDI_02002 2.6e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NICMNEDI_02004 5.3e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NICMNEDI_02005 3.6e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NICMNEDI_02006 2e-79 yngA S membrane
NICMNEDI_02007 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NICMNEDI_02008 5.5e-104 yngC S membrane-associated protein
NICMNEDI_02009 3.3e-233 nrnB S phosphohydrolase (DHH superfamily)
NICMNEDI_02010 1.3e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NICMNEDI_02011 9.2e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NICMNEDI_02012 1.1e-14 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NICMNEDI_02013 3.5e-130 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NICMNEDI_02014 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NICMNEDI_02015 3.1e-248 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NICMNEDI_02016 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NICMNEDI_02017 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NICMNEDI_02018 1e-303 yngK T Glycosyl hydrolase-like 10
NICMNEDI_02019 6.8e-63 yngL S Protein of unknown function (DUF1360)
NICMNEDI_02020 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NICMNEDI_02021 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_02022 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_02023 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_02024 1.1e-33 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_02025 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_02026 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_02027 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_02028 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_02029 1.4e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NICMNEDI_02030 1.7e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
NICMNEDI_02031 1.9e-245 yoeA V MATE efflux family protein
NICMNEDI_02032 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NICMNEDI_02034 2.2e-96 L Integrase
NICMNEDI_02035 8.7e-34 yoeD G Helix-turn-helix domain
NICMNEDI_02036 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NICMNEDI_02037 3e-156 gltR1 K Transcriptional regulator
NICMNEDI_02038 3.3e-183 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NICMNEDI_02039 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NICMNEDI_02040 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NICMNEDI_02041 7.8e-155 gltC K Transcriptional regulator
NICMNEDI_02042 2.1e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NICMNEDI_02043 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NICMNEDI_02044 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NICMNEDI_02045 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_02046 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
NICMNEDI_02047 1.3e-134 yoxB
NICMNEDI_02048 1.9e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NICMNEDI_02049 1.1e-125 V ABC-2 family transporter protein
NICMNEDI_02050 6.4e-94 V ABC-2 family transporter protein
NICMNEDI_02051 3.3e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
NICMNEDI_02052 6.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
NICMNEDI_02053 9.9e-233 yoaB EGP Major facilitator Superfamily
NICMNEDI_02054 8.5e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NICMNEDI_02055 1.2e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NICMNEDI_02056 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NICMNEDI_02057 4.6e-27 yoaF
NICMNEDI_02058 1.9e-171 iolT EGP Major facilitator Superfamily
NICMNEDI_02059 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
NICMNEDI_02060 1.2e-150 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
NICMNEDI_02061 4.4e-90 purR K Transcriptional regulator
NICMNEDI_02062 2.2e-07
NICMNEDI_02063 2.6e-13
NICMNEDI_02064 7.7e-35 S Protein of unknown function (DUF4025)
NICMNEDI_02065 3.8e-179 mcpU NT methyl-accepting chemotaxis protein
NICMNEDI_02066 3.7e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NICMNEDI_02067 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NICMNEDI_02068 1.5e-110 yoaK S Membrane
NICMNEDI_02069 7.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NICMNEDI_02070 3.2e-132 yoqW S Belongs to the SOS response-associated peptidase family
NICMNEDI_02073 1e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
NICMNEDI_02075 1.1e-84
NICMNEDI_02076 7.1e-172 yoaR V vancomycin resistance protein
NICMNEDI_02077 7.3e-75 yoaS S Protein of unknown function (DUF2975)
NICMNEDI_02078 6e-30 yozG K Transcriptional regulator
NICMNEDI_02079 1.6e-148 yoaT S Protein of unknown function (DUF817)
NICMNEDI_02080 3.3e-158 yoaU K LysR substrate binding domain
NICMNEDI_02081 1.9e-158 yijE EG EamA-like transporter family
NICMNEDI_02082 7e-77 yoaW
NICMNEDI_02083 7.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NICMNEDI_02084 2.4e-167 bla 3.5.2.6 V beta-lactamase
NICMNEDI_02087 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NICMNEDI_02088 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NICMNEDI_02090 2.8e-47
NICMNEDI_02091 9.7e-85 S SMI1-KNR4 cell-wall
NICMNEDI_02092 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NICMNEDI_02093 3.7e-102 yokH G SMI1 / KNR4 family
NICMNEDI_02094 6.4e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NICMNEDI_02095 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NICMNEDI_02096 8e-134 yobQ K helix_turn_helix, arabinose operon control protein
NICMNEDI_02097 7.7e-140 yobR 2.3.1.1 J FR47-like protein
NICMNEDI_02098 1.3e-97 yobS K Transcriptional regulator
NICMNEDI_02099 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NICMNEDI_02100 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
NICMNEDI_02101 7.3e-172 yobV K WYL domain
NICMNEDI_02102 6.1e-94 yobW
NICMNEDI_02103 1e-51 czrA K transcriptional
NICMNEDI_02104 5.8e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NICMNEDI_02105 1.5e-92 yozB S membrane
NICMNEDI_02106 6.4e-145
NICMNEDI_02107 1.6e-93 yocC
NICMNEDI_02108 9.3e-186 yocD 3.4.17.13 V peptidase S66
NICMNEDI_02109 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NICMNEDI_02110 3.2e-198 desK 2.7.13.3 T Histidine kinase
NICMNEDI_02111 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NICMNEDI_02112 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NICMNEDI_02113 0.0 recQ 3.6.4.12 L DNA helicase
NICMNEDI_02114 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NICMNEDI_02115 3.3e-83 dksA T general stress protein
NICMNEDI_02116 1.2e-52 yocL
NICMNEDI_02117 6.2e-32
NICMNEDI_02118 2.2e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NICMNEDI_02119 1.1e-40 yozN
NICMNEDI_02120 1.9e-36 yocN
NICMNEDI_02121 4.2e-56 yozO S Bacterial PH domain
NICMNEDI_02122 2.7e-31 yozC
NICMNEDI_02123 2e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NICMNEDI_02124 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NICMNEDI_02125 6e-165 sodA 1.15.1.1 P Superoxide dismutase
NICMNEDI_02126 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NICMNEDI_02127 5.6e-167 yocS S -transporter
NICMNEDI_02128 2.1e-150 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NICMNEDI_02129 6.5e-36 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NICMNEDI_02130 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NICMNEDI_02131 0.0 yojO P Von Willebrand factor
NICMNEDI_02132 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
NICMNEDI_02133 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NICMNEDI_02134 2.7e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NICMNEDI_02135 9e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NICMNEDI_02136 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NICMNEDI_02138 4.2e-245 norM V Multidrug efflux pump
NICMNEDI_02139 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NICMNEDI_02140 2.1e-125 yojG S deacetylase
NICMNEDI_02141 2.2e-60 yojF S Protein of unknown function (DUF1806)
NICMNEDI_02142 1.5e-43
NICMNEDI_02143 6.6e-162 rarD S -transporter
NICMNEDI_02144 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
NICMNEDI_02145 2.2e-10 yozR S COG0071 Molecular chaperone (small heat shock protein)
NICMNEDI_02146 5e-206 gntP EG COG2610 H gluconate symporter and related permeases
NICMNEDI_02147 4.7e-64 yodA S tautomerase
NICMNEDI_02148 4.4e-55 yodB K transcriptional
NICMNEDI_02149 1.4e-107 yodC C nitroreductase
NICMNEDI_02150 8.5e-113 mhqD S Carboxylesterase
NICMNEDI_02151 1.7e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
NICMNEDI_02152 6.2e-28 S Protein of unknown function (DUF3311)
NICMNEDI_02153 8.7e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NICMNEDI_02154 4.1e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NICMNEDI_02155 2.4e-127 yodH Q Methyltransferase
NICMNEDI_02156 1.5e-23 yodI
NICMNEDI_02157 2.1e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NICMNEDI_02158 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NICMNEDI_02159 5.3e-09
NICMNEDI_02160 3.6e-54 yodL S YodL-like
NICMNEDI_02161 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
NICMNEDI_02162 2.8e-24 yozD S YozD-like protein
NICMNEDI_02164 6e-123 yodN
NICMNEDI_02165 1.4e-36 yozE S Belongs to the UPF0346 family
NICMNEDI_02166 2.9e-47 yokU S YokU-like protein, putative antitoxin
NICMNEDI_02167 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NICMNEDI_02168 1.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NICMNEDI_02169 7.1e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NICMNEDI_02170 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NICMNEDI_02171 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NICMNEDI_02172 2.3e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NICMNEDI_02174 5e-142 yiiD K acetyltransferase
NICMNEDI_02175 3.6e-254 cgeD M maturation of the outermost layer of the spore
NICMNEDI_02176 4.5e-38 cgeC
NICMNEDI_02177 3.1e-63 cgeA
NICMNEDI_02178 2.6e-177 cgeB S Spore maturation protein
NICMNEDI_02179 1.4e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NICMNEDI_02180 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
NICMNEDI_02181 6.4e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NICMNEDI_02182 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NICMNEDI_02183 1.6e-70 ypoP K transcriptional
NICMNEDI_02184 7.6e-223 mepA V MATE efflux family protein
NICMNEDI_02185 1.6e-28 ypmT S Uncharacterized ympT
NICMNEDI_02186 1.1e-98 ypmS S protein conserved in bacteria
NICMNEDI_02187 2.8e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NICMNEDI_02188 9.3e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NICMNEDI_02189 3.4e-39 ypmP S Protein of unknown function (DUF2535)
NICMNEDI_02190 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NICMNEDI_02191 4e-184 pspF K Transcriptional regulator
NICMNEDI_02192 4.2e-110 hlyIII S protein, Hemolysin III
NICMNEDI_02193 1.2e-109 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NICMNEDI_02194 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NICMNEDI_02195 7.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NICMNEDI_02196 7.8e-114 ypjP S YpjP-like protein
NICMNEDI_02197 1.8e-144 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NICMNEDI_02198 1.7e-75 yphP S Belongs to the UPF0403 family
NICMNEDI_02199 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NICMNEDI_02200 6.4e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
NICMNEDI_02201 1.3e-108 ypgQ S phosphohydrolase
NICMNEDI_02202 2.6e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NICMNEDI_02203 1.4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NICMNEDI_02204 3.5e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NICMNEDI_02205 1e-30 cspD K Cold-shock protein
NICMNEDI_02206 3.8e-16 degR
NICMNEDI_02207 8.1e-31 S Protein of unknown function (DUF2564)
NICMNEDI_02208 3e-29 ypeQ S Zinc-finger
NICMNEDI_02209 1.9e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NICMNEDI_02210 1e-102 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NICMNEDI_02211 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
NICMNEDI_02213 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NICMNEDI_02214 2e-07
NICMNEDI_02215 8.5e-38 ypbS S Protein of unknown function (DUF2533)
NICMNEDI_02216 0.0 ypbR S Dynamin family
NICMNEDI_02218 5.1e-87 ypbQ S protein conserved in bacteria
NICMNEDI_02219 4.8e-207 bcsA Q Naringenin-chalcone synthase
NICMNEDI_02220 3.8e-227 pbuX F xanthine
NICMNEDI_02221 2.8e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NICMNEDI_02222 5.1e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NICMNEDI_02223 8.2e-140 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NICMNEDI_02224 3.3e-101 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NICMNEDI_02225 2.7e-185 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NICMNEDI_02226 1.5e-186 ptxS K transcriptional
NICMNEDI_02227 2.9e-156 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NICMNEDI_02228 8.8e-112 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NICMNEDI_02229 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NICMNEDI_02231 6.3e-139 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NICMNEDI_02232 7e-62 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NICMNEDI_02233 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NICMNEDI_02234 6.3e-91 ypsA S Belongs to the UPF0398 family
NICMNEDI_02235 8.1e-235 yprB L RNase_H superfamily
NICMNEDI_02236 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NICMNEDI_02237 3.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NICMNEDI_02238 3.6e-70 hspX O Belongs to the small heat shock protein (HSP20) family
NICMNEDI_02239 1e-47 yppG S YppG-like protein
NICMNEDI_02241 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
NICMNEDI_02244 5.9e-185 yppC S Protein of unknown function (DUF2515)
NICMNEDI_02245 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NICMNEDI_02246 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NICMNEDI_02247 2e-91 ypoC
NICMNEDI_02248 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NICMNEDI_02249 2.2e-128 dnaD L DNA replication protein DnaD
NICMNEDI_02250 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NICMNEDI_02251 6.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NICMNEDI_02252 2.2e-79 ypmB S protein conserved in bacteria
NICMNEDI_02253 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NICMNEDI_02254 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NICMNEDI_02255 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NICMNEDI_02256 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NICMNEDI_02257 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NICMNEDI_02258 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NICMNEDI_02259 6.6e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NICMNEDI_02260 4.1e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NICMNEDI_02261 3.4e-129 bshB1 S proteins, LmbE homologs
NICMNEDI_02262 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NICMNEDI_02263 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NICMNEDI_02264 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NICMNEDI_02265 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NICMNEDI_02266 1e-142 ypjB S sporulation protein
NICMNEDI_02267 4.9e-97 ypjA S membrane
NICMNEDI_02268 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NICMNEDI_02269 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NICMNEDI_02270 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NICMNEDI_02271 4.2e-77 ypiF S Protein of unknown function (DUF2487)
NICMNEDI_02272 8.1e-99 ypiB S Belongs to the UPF0302 family
NICMNEDI_02273 1.9e-231 S COG0457 FOG TPR repeat
NICMNEDI_02274 6e-149 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NICMNEDI_02275 1.2e-67 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NICMNEDI_02276 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NICMNEDI_02277 7.8e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NICMNEDI_02278 6.8e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NICMNEDI_02279 3.2e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NICMNEDI_02280 5.1e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NICMNEDI_02281 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NICMNEDI_02282 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NICMNEDI_02283 6.8e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NICMNEDI_02284 3.9e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NICMNEDI_02285 1.7e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NICMNEDI_02286 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NICMNEDI_02287 1.8e-143 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NICMNEDI_02288 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NICMNEDI_02289 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NICMNEDI_02290 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NICMNEDI_02291 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NICMNEDI_02292 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NICMNEDI_02293 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NICMNEDI_02294 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NICMNEDI_02295 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NICMNEDI_02296 6e-137 yphF
NICMNEDI_02297 1.6e-18 yphE S Protein of unknown function (DUF2768)
NICMNEDI_02298 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NICMNEDI_02299 1.1e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NICMNEDI_02300 2.3e-27 ypzH
NICMNEDI_02301 2.5e-161 seaA S YIEGIA protein
NICMNEDI_02302 5.1e-102 yphA
NICMNEDI_02303 3e-07 S YpzI-like protein
NICMNEDI_02304 1.2e-149 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NICMNEDI_02305 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NICMNEDI_02306 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NICMNEDI_02307 1.8e-23 S Family of unknown function (DUF5359)
NICMNEDI_02308 9.2e-113 ypfA M Flagellar protein YcgR
NICMNEDI_02309 3.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NICMNEDI_02310 1.1e-89 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NICMNEDI_02311 5e-119 prsW S Involved in the degradation of specific anti-sigma factors
NICMNEDI_02312 2.8e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NICMNEDI_02313 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NICMNEDI_02314 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NICMNEDI_02315 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
NICMNEDI_02316 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NICMNEDI_02317 4.6e-81 ypbE M Lysin motif
NICMNEDI_02318 2.2e-100 ypbD S metal-dependent membrane protease
NICMNEDI_02319 9.2e-286 recQ 3.6.4.12 L DNA helicase
NICMNEDI_02320 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
NICMNEDI_02321 4.7e-41 fer C Ferredoxin
NICMNEDI_02322 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NICMNEDI_02323 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NICMNEDI_02324 2.1e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NICMNEDI_02325 1.5e-184 rsiX
NICMNEDI_02326 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NICMNEDI_02327 0.0 resE 2.7.13.3 T Histidine kinase
NICMNEDI_02328 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_02329 6.7e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NICMNEDI_02330 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NICMNEDI_02331 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NICMNEDI_02332 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NICMNEDI_02333 1.9e-87 spmB S Spore maturation protein
NICMNEDI_02334 3.5e-103 spmA S Spore maturation protein
NICMNEDI_02335 1.7e-179 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NICMNEDI_02336 5.3e-24 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NICMNEDI_02337 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NICMNEDI_02338 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NICMNEDI_02339 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NICMNEDI_02340 1e-90 ypuF S Domain of unknown function (DUF309)
NICMNEDI_02341 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NICMNEDI_02342 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NICMNEDI_02343 4.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NICMNEDI_02344 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
NICMNEDI_02345 2.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NICMNEDI_02346 7.8e-55 ypuD
NICMNEDI_02347 5.8e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NICMNEDI_02348 7.3e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NICMNEDI_02350 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NICMNEDI_02351 8.1e-149 ypuA S Secreted protein
NICMNEDI_02352 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NICMNEDI_02353 1.4e-273 spoVAF EG Stage V sporulation protein AF
NICMNEDI_02354 1.4e-110 spoVAEA S stage V sporulation protein
NICMNEDI_02355 2.2e-57 spoVAEB S stage V sporulation protein
NICMNEDI_02356 9e-192 spoVAD I Stage V sporulation protein AD
NICMNEDI_02357 2.3e-78 spoVAC S stage V sporulation protein AC
NICMNEDI_02358 1e-67 spoVAB S Stage V sporulation protein AB
NICMNEDI_02359 9.6e-112 spoVAA S Stage V sporulation protein AA
NICMNEDI_02360 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NICMNEDI_02361 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NICMNEDI_02362 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NICMNEDI_02363 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NICMNEDI_02364 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NICMNEDI_02365 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NICMNEDI_02366 3.7e-165 xerD L recombinase XerD
NICMNEDI_02367 3.7e-37 S Protein of unknown function (DUF4227)
NICMNEDI_02368 2.4e-80 fur P Belongs to the Fur family
NICMNEDI_02369 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NICMNEDI_02370 1.9e-30 yqkK
NICMNEDI_02371 5.5e-242 mleA 1.1.1.38 C malic enzyme
NICMNEDI_02372 9.1e-235 mleN C Na H antiporter
NICMNEDI_02373 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NICMNEDI_02374 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
NICMNEDI_02375 4.5e-58 ansR K Transcriptional regulator
NICMNEDI_02376 8.1e-221 yqxK 3.6.4.12 L DNA helicase
NICMNEDI_02377 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NICMNEDI_02379 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NICMNEDI_02380 3.1e-12 yqkE S Protein of unknown function (DUF3886)
NICMNEDI_02381 1.4e-170 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NICMNEDI_02382 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NICMNEDI_02383 3.7e-54 yqkB S Belongs to the HesB IscA family
NICMNEDI_02384 6.3e-193 yqkA K GrpB protein
NICMNEDI_02385 2.6e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NICMNEDI_02386 3.6e-87 yqjY K acetyltransferase
NICMNEDI_02387 5.7e-50 S YolD-like protein
NICMNEDI_02388 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NICMNEDI_02390 3.8e-224 yqjV G Major Facilitator Superfamily
NICMNEDI_02392 4.6e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NICMNEDI_02393 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NICMNEDI_02394 3.9e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NICMNEDI_02395 5.9e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_02396 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NICMNEDI_02397 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NICMNEDI_02398 0.0 rocB E arginine degradation protein
NICMNEDI_02399 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NICMNEDI_02400 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NICMNEDI_02401 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NICMNEDI_02402 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NICMNEDI_02403 4.4e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NICMNEDI_02404 2.6e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NICMNEDI_02405 1.2e-230 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NICMNEDI_02406 4.5e-24 yqzJ
NICMNEDI_02407 3.2e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NICMNEDI_02408 4.6e-137 yqjF S Uncharacterized conserved protein (COG2071)
NICMNEDI_02409 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NICMNEDI_02410 1.6e-285 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NICMNEDI_02411 1e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NICMNEDI_02413 3e-98 yqjB S protein conserved in bacteria
NICMNEDI_02414 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
NICMNEDI_02415 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NICMNEDI_02416 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NICMNEDI_02417 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
NICMNEDI_02418 9.3e-77 yqiW S Belongs to the UPF0403 family
NICMNEDI_02419 2.6e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NICMNEDI_02420 7.9e-208 norA EGP Major facilitator Superfamily
NICMNEDI_02421 2.6e-152 bmrR K helix_turn_helix, mercury resistance
NICMNEDI_02422 3.2e-218 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NICMNEDI_02423 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NICMNEDI_02424 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NICMNEDI_02425 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NICMNEDI_02426 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NICMNEDI_02427 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NICMNEDI_02428 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NICMNEDI_02429 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NICMNEDI_02430 4e-34 yqzF S Protein of unknown function (DUF2627)
NICMNEDI_02431 1.3e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NICMNEDI_02432 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NICMNEDI_02433 1.2e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NICMNEDI_02434 2.2e-210 mmgC I acyl-CoA dehydrogenase
NICMNEDI_02435 4.2e-130 hbdA 1.1.1.157 I Dehydrogenase
NICMNEDI_02436 2.9e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
NICMNEDI_02437 1.2e-132 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NICMNEDI_02438 2.7e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NICMNEDI_02439 6e-27
NICMNEDI_02440 3.6e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NICMNEDI_02442 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NICMNEDI_02443 4.7e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NICMNEDI_02444 1.1e-306 recN L May be involved in recombinational repair of damaged DNA
NICMNEDI_02445 1.9e-77 argR K Regulates arginine biosynthesis genes
NICMNEDI_02446 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NICMNEDI_02447 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NICMNEDI_02448 8.5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NICMNEDI_02449 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NICMNEDI_02450 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NICMNEDI_02451 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NICMNEDI_02452 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NICMNEDI_02453 2.1e-67 yqhY S protein conserved in bacteria
NICMNEDI_02454 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NICMNEDI_02455 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NICMNEDI_02456 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NICMNEDI_02457 2.2e-109 spoIIIAG S stage III sporulation protein AG
NICMNEDI_02458 2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NICMNEDI_02459 3.8e-197 spoIIIAE S stage III sporulation protein AE
NICMNEDI_02460 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NICMNEDI_02461 7.6e-29 spoIIIAC S stage III sporulation protein AC
NICMNEDI_02462 4.1e-84 spoIIIAB S Stage III sporulation protein
NICMNEDI_02463 4e-170 spoIIIAA S stage III sporulation protein AA
NICMNEDI_02464 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NICMNEDI_02465 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NICMNEDI_02466 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NICMNEDI_02467 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NICMNEDI_02468 2.3e-93 yqhR S Conserved membrane protein YqhR
NICMNEDI_02469 1.4e-173 yqhQ S Protein of unknown function (DUF1385)
NICMNEDI_02470 2.2e-61 yqhP
NICMNEDI_02471 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
NICMNEDI_02472 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NICMNEDI_02473 4.1e-95 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NICMNEDI_02474 1.2e-42 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NICMNEDI_02475 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NICMNEDI_02476 2e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NICMNEDI_02477 4.9e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NICMNEDI_02478 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NICMNEDI_02479 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NICMNEDI_02480 1e-150 yqhG S Bacterial protein YqhG of unknown function
NICMNEDI_02481 3.6e-24 sinI S Anti-repressor SinI
NICMNEDI_02482 8.8e-54 sinR K transcriptional
NICMNEDI_02483 3.8e-141 tasA S Cell division protein FtsN
NICMNEDI_02484 6.7e-59 sipW 3.4.21.89 U Signal peptidase
NICMNEDI_02485 1e-110 yqxM
NICMNEDI_02486 2.6e-52 yqzG S Protein of unknown function (DUF3889)
NICMNEDI_02487 5.2e-26 yqzE S YqzE-like protein
NICMNEDI_02488 1.2e-43 S ComG operon protein 7
NICMNEDI_02489 4.1e-46 comGF U Putative Competence protein ComGF
NICMNEDI_02490 3.1e-59 comGE
NICMNEDI_02491 9.5e-66 gspH NU protein transport across the cell outer membrane
NICMNEDI_02492 1.4e-47 comGC U Required for transformation and DNA binding
NICMNEDI_02493 1.3e-172 comGB NU COG1459 Type II secretory pathway, component PulF
NICMNEDI_02494 1.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NICMNEDI_02496 7.2e-175 corA P Mg2 transporter protein
NICMNEDI_02497 4.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NICMNEDI_02498 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NICMNEDI_02500 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NICMNEDI_02501 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NICMNEDI_02502 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NICMNEDI_02503 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NICMNEDI_02504 6.9e-50 yqgV S Thiamine-binding protein
NICMNEDI_02505 1.1e-197 yqgU
NICMNEDI_02506 1e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NICMNEDI_02507 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NICMNEDI_02508 3.4e-180 glcK 2.7.1.2 G Glucokinase
NICMNEDI_02509 4.3e-33 yqgQ S Protein conserved in bacteria
NICMNEDI_02510 4.7e-261 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NICMNEDI_02511 2.5e-09 yqgO
NICMNEDI_02512 2.8e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NICMNEDI_02513 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NICMNEDI_02514 7.8e-194 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NICMNEDI_02516 9.2e-51 yqzD
NICMNEDI_02517 7.3e-72 yqzC S YceG-like family
NICMNEDI_02518 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NICMNEDI_02519 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NICMNEDI_02520 1.3e-157 pstA P Phosphate transport system permease
NICMNEDI_02521 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NICMNEDI_02522 2.6e-150 pstS P Phosphate
NICMNEDI_02523 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NICMNEDI_02524 2.5e-231 yqgE EGP Major facilitator superfamily
NICMNEDI_02525 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NICMNEDI_02526 2.6e-72 yqgC S protein conserved in bacteria
NICMNEDI_02527 3.9e-131 yqgB S Protein of unknown function (DUF1189)
NICMNEDI_02528 5.8e-46 yqfZ M LysM domain
NICMNEDI_02529 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NICMNEDI_02530 4.3e-62 yqfX S membrane
NICMNEDI_02531 4.6e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NICMNEDI_02532 7.1e-77 zur P Belongs to the Fur family
NICMNEDI_02533 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NICMNEDI_02534 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NICMNEDI_02535 5.7e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NICMNEDI_02536 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NICMNEDI_02537 5.4e-13 yqfQ S YqfQ-like protein
NICMNEDI_02538 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NICMNEDI_02539 1.3e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NICMNEDI_02540 8.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
NICMNEDI_02541 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NICMNEDI_02542 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NICMNEDI_02543 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NICMNEDI_02544 4.5e-88 yaiI S Belongs to the UPF0178 family
NICMNEDI_02545 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NICMNEDI_02546 4.5e-112 ccpN K CBS domain
NICMNEDI_02547 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NICMNEDI_02548 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NICMNEDI_02549 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
NICMNEDI_02550 8.4e-19 S YqzL-like protein
NICMNEDI_02551 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NICMNEDI_02552 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NICMNEDI_02553 3.9e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NICMNEDI_02554 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NICMNEDI_02555 0.0 yqfF S membrane-associated HD superfamily hydrolase
NICMNEDI_02557 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NICMNEDI_02558 4.3e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NICMNEDI_02559 2.7e-45 yqfC S sporulation protein YqfC
NICMNEDI_02560 5.1e-24 yqfB
NICMNEDI_02561 1.8e-106 yqfA S UPF0365 protein
NICMNEDI_02562 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NICMNEDI_02563 2.5e-61 yqeY S Yqey-like protein
NICMNEDI_02564 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NICMNEDI_02565 4.1e-157 yqeW P COG1283 Na phosphate symporter
NICMNEDI_02566 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NICMNEDI_02567 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NICMNEDI_02568 5.4e-175 prmA J Methylates ribosomal protein L11
NICMNEDI_02569 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NICMNEDI_02570 0.0 dnaK O Heat shock 70 kDa protein
NICMNEDI_02571 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NICMNEDI_02572 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NICMNEDI_02573 7.7e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
NICMNEDI_02574 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NICMNEDI_02575 7.2e-53 yqxA S Protein of unknown function (DUF3679)
NICMNEDI_02576 2e-222 spoIIP M stage II sporulation protein P
NICMNEDI_02577 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NICMNEDI_02578 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NICMNEDI_02579 1.3e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
NICMNEDI_02580 4.1e-15 S YqzM-like protein
NICMNEDI_02581 0.0 comEC S Competence protein ComEC
NICMNEDI_02582 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NICMNEDI_02583 4.3e-96 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NICMNEDI_02584 5.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NICMNEDI_02585 1.1e-138 yqeM Q Methyltransferase
NICMNEDI_02586 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NICMNEDI_02587 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NICMNEDI_02588 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NICMNEDI_02589 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NICMNEDI_02590 1.7e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NICMNEDI_02591 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NICMNEDI_02592 5.3e-95 yqeG S hydrolase of the HAD superfamily
NICMNEDI_02594 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NICMNEDI_02595 8e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NICMNEDI_02596 1.7e-97 yqeD S SNARE associated Golgi protein
NICMNEDI_02597 4.7e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NICMNEDI_02598 5.7e-132 yqeB
NICMNEDI_02599 1.2e-73 nucB M Deoxyribonuclease NucA/NucB
NICMNEDI_02600 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NICMNEDI_02601 3e-35 cisA2 L Recombinase
NICMNEDI_02602 1.3e-100 K acetyltransferase
NICMNEDI_02603 8.5e-42 rplV S ASCH
NICMNEDI_02604 7e-31 2.7.4.3 F AAA domain
NICMNEDI_02605 3e-13 S Domain of Unknown Function with PDB structure (DUF3850)
NICMNEDI_02607 8e-157 S Aspartate phosphatase response regulator
NICMNEDI_02608 3.2e-163 yobL S Bacterial EndoU nuclease
NICMNEDI_02609 5.7e-26 S SMI1-KNR4 cell-wall
NICMNEDI_02610 3.9e-22 S SMI1-KNR4 cell-wall
NICMNEDI_02611 1.3e-108 EGP Major facilitator Superfamily
NICMNEDI_02612 3.4e-09 pcaC 1.1.1.31, 3.1.1.24, 4.1.1.44 S Carboxymuconolactone decarboxylase family
NICMNEDI_02613 1.2e-36 K Transcriptional regulator
NICMNEDI_02614 2.1e-122 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NICMNEDI_02615 1.3e-27 S phage terminase, large subunit
NICMNEDI_02616 5.9e-97 yqaS L DNA packaging
NICMNEDI_02617 1.6e-23
NICMNEDI_02618 5.4e-79 S Protein of unknown function (DUF3800)
NICMNEDI_02619 8.3e-60 L Phage integrase family
NICMNEDI_02620 1.7e-40 wecC 1.1.1.336 M ArpU family transcriptional regulator
NICMNEDI_02622 3.6e-31 yqaO S Phage-like element PBSX protein XtrA
NICMNEDI_02623 3.5e-71 rusA L Endodeoxyribonuclease RusA
NICMNEDI_02626 7.6e-160 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
NICMNEDI_02627 7.9e-89 K Transcriptional regulator PadR-like family
NICMNEDI_02628 6.4e-96 adk 2.7.4.3 F adenylate kinase activity
NICMNEDI_02630 3.6e-43 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NICMNEDI_02631 2e-68 psiE S Protein PsiE homolog
NICMNEDI_02632 4.5e-236 yrkQ T Histidine kinase
NICMNEDI_02633 4.1e-127 T Transcriptional regulator
NICMNEDI_02634 1.7e-221 yrkO P Protein of unknown function (DUF418)
NICMNEDI_02635 1.8e-101 yrkN K Acetyltransferase (GNAT) family
NICMNEDI_02636 1.5e-97 ywrO S Flavodoxin-like fold
NICMNEDI_02637 2.8e-79 S Protein of unknown function with HXXEE motif
NICMNEDI_02638 8.4e-113 yrkJ S membrane transporter protein
NICMNEDI_02639 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
NICMNEDI_02640 1.5e-211 yrkH P Rhodanese Homology Domain
NICMNEDI_02641 4.9e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
NICMNEDI_02642 2.5e-83 yrkE O DsrE/DsrF/DrsH-like family
NICMNEDI_02643 7.8e-39 yrkD S protein conserved in bacteria
NICMNEDI_02644 3.8e-107 yrkC G Cupin domain
NICMNEDI_02645 3.1e-150 bltR K helix_turn_helix, mercury resistance
NICMNEDI_02646 6.7e-210 blt EGP Major facilitator Superfamily
NICMNEDI_02647 5e-81 bltD 2.3.1.57 K FR47-like protein
NICMNEDI_02648 6.7e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NICMNEDI_02649 3.9e-16 S YrzO-like protein
NICMNEDI_02650 6e-169 yrdR EG EamA-like transporter family
NICMNEDI_02651 3.9e-159 yrdQ K Transcriptional regulator
NICMNEDI_02652 2.8e-196 trkA P Oxidoreductase
NICMNEDI_02653 7.7e-153 czcD P COG1230 Co Zn Cd efflux system component
NICMNEDI_02654 3e-17 yodA S tautomerase
NICMNEDI_02655 1.1e-224 brnQ E Component of the transport system for branched-chain amino acids
NICMNEDI_02656 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NICMNEDI_02657 9.6e-138 azlC E AzlC protein
NICMNEDI_02658 5.3e-78 bkdR K helix_turn_helix ASNC type
NICMNEDI_02659 8.8e-41 yrdF K ribonuclease inhibitor
NICMNEDI_02661 1.7e-221 cypA C Cytochrome P450
NICMNEDI_02662 7.2e-39 K Acetyltransferase (GNAT) family
NICMNEDI_02663 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
NICMNEDI_02664 1.5e-54 S Protein of unknown function (DUF2568)
NICMNEDI_02665 7.7e-29
NICMNEDI_02666 7.2e-40
NICMNEDI_02667 6.4e-90 yrdA S DinB family
NICMNEDI_02668 5.1e-164 aadK G Streptomycin adenylyltransferase
NICMNEDI_02669 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NICMNEDI_02670 1.9e-144 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NICMNEDI_02671 8.7e-125 yrpD S Domain of unknown function, YrpD
NICMNEDI_02673 4.9e-110 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NICMNEDI_02674 1.3e-93 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NICMNEDI_02675 1.7e-187 yrpG C Aldo/keto reductase family
NICMNEDI_02676 4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NICMNEDI_02677 3.8e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NICMNEDI_02678 9.9e-149 S Alpha beta hydrolase
NICMNEDI_02679 1.7e-60 T sh3 domain protein
NICMNEDI_02680 2.4e-61 T sh3 domain protein
NICMNEDI_02681 1.3e-66 E Glyoxalase-like domain
NICMNEDI_02682 5.3e-37 yraG
NICMNEDI_02683 6.4e-63 yraF M Spore coat protein
NICMNEDI_02684 1.1e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NICMNEDI_02685 1.7e-25 yraE
NICMNEDI_02686 1.1e-49 yraD M Spore coat protein
NICMNEDI_02687 4.3e-47 yraB K helix_turn_helix, mercury resistance
NICMNEDI_02688 4e-24 yphJ 4.1.1.44 S peroxiredoxin activity
NICMNEDI_02689 2.8e-196 adhA 1.1.1.1 C alcohol dehydrogenase
NICMNEDI_02690 8.5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NICMNEDI_02691 1.6e-191 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NICMNEDI_02692 1.3e-190 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NICMNEDI_02693 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NICMNEDI_02694 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NICMNEDI_02695 8.2e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NICMNEDI_02696 3.3e-74 levD 2.7.1.202 G PTS system fructose IIA component
NICMNEDI_02697 0.0 levR K PTS system fructose IIA component
NICMNEDI_02698 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NICMNEDI_02699 3.6e-106 yrhP E LysE type translocator
NICMNEDI_02700 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
NICMNEDI_02701 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NICMNEDI_02702 6.1e-149 rsiV S Protein of unknown function (DUF3298)
NICMNEDI_02703 0.0 yrhL I Acyltransferase family
NICMNEDI_02704 1.2e-43 yrhK S YrhK-like protein
NICMNEDI_02705 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NICMNEDI_02706 1.4e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NICMNEDI_02707 2.3e-93 yrhH Q methyltransferase
NICMNEDI_02710 6.7e-142 focA P Formate nitrite
NICMNEDI_02711 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
NICMNEDI_02712 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NICMNEDI_02713 5.4e-78 yrhD S Protein of unknown function (DUF1641)
NICMNEDI_02714 4.6e-35 yrhC S YrhC-like protein
NICMNEDI_02715 1.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NICMNEDI_02716 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NICMNEDI_02717 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NICMNEDI_02718 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NICMNEDI_02719 1e-25 yrzA S Protein of unknown function (DUF2536)
NICMNEDI_02720 4.2e-63 yrrS S Protein of unknown function (DUF1510)
NICMNEDI_02721 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NICMNEDI_02722 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NICMNEDI_02723 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NICMNEDI_02724 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NICMNEDI_02725 1.1e-172 yegQ O Peptidase U32
NICMNEDI_02726 3.8e-119 yrrM 2.1.1.104 S O-methyltransferase
NICMNEDI_02727 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NICMNEDI_02728 1.2e-45 yrzB S Belongs to the UPF0473 family
NICMNEDI_02729 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NICMNEDI_02730 1.7e-41 yrzL S Belongs to the UPF0297 family
NICMNEDI_02731 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NICMNEDI_02732 7.8e-170 yrrI S AI-2E family transporter
NICMNEDI_02733 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NICMNEDI_02734 4.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
NICMNEDI_02735 8e-109 gluC P ABC transporter
NICMNEDI_02736 7.6e-107 glnP P ABC transporter
NICMNEDI_02737 1.7e-07 S Protein of unknown function (DUF3918)
NICMNEDI_02738 9.8e-31 yrzR
NICMNEDI_02739 1.2e-82 yrrD S protein conserved in bacteria
NICMNEDI_02740 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NICMNEDI_02741 1.4e-15 S COG0457 FOG TPR repeat
NICMNEDI_02742 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NICMNEDI_02743 3.7e-210 iscS 2.8.1.7 E Cysteine desulfurase
NICMNEDI_02744 1.2e-70 cymR K Transcriptional regulator
NICMNEDI_02745 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NICMNEDI_02746 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NICMNEDI_02747 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NICMNEDI_02748 1.4e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
NICMNEDI_02750 1.5e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
NICMNEDI_02751 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NICMNEDI_02752 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NICMNEDI_02753 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NICMNEDI_02754 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NICMNEDI_02755 1.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
NICMNEDI_02756 1.1e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NICMNEDI_02757 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NICMNEDI_02758 1.6e-48 yrzD S Post-transcriptional regulator
NICMNEDI_02759 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NICMNEDI_02760 1.3e-111 yrbG S membrane
NICMNEDI_02761 2.2e-73 yrzE S Protein of unknown function (DUF3792)
NICMNEDI_02762 8e-39 yajC U Preprotein translocase subunit YajC
NICMNEDI_02763 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NICMNEDI_02764 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NICMNEDI_02765 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NICMNEDI_02766 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NICMNEDI_02767 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NICMNEDI_02768 4.8e-93 bofC S BofC C-terminal domain
NICMNEDI_02769 2.6e-252 csbX EGP Major facilitator Superfamily
NICMNEDI_02770 8.2e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NICMNEDI_02771 1.6e-117 yrzF T serine threonine protein kinase
NICMNEDI_02773 3.1e-51 S Family of unknown function (DUF5412)
NICMNEDI_02774 3.1e-262 alsT E Sodium alanine symporter
NICMNEDI_02775 3.2e-127 yebC K transcriptional regulatory protein
NICMNEDI_02776 1.3e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NICMNEDI_02777 8.3e-157 safA M spore coat assembly protein SafA
NICMNEDI_02778 1e-212 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NICMNEDI_02779 2.3e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NICMNEDI_02780 2.9e-301 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NICMNEDI_02781 1.3e-229 nifS 2.8.1.7 E Cysteine desulfurase
NICMNEDI_02782 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NICMNEDI_02783 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
NICMNEDI_02784 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NICMNEDI_02785 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NICMNEDI_02786 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NICMNEDI_02787 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NICMNEDI_02788 4.1e-56 ysxB J ribosomal protein
NICMNEDI_02789 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NICMNEDI_02790 2.7e-160 spoIVFB S Stage IV sporulation protein
NICMNEDI_02791 8.5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NICMNEDI_02792 8e-143 minD D Belongs to the ParA family
NICMNEDI_02793 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NICMNEDI_02794 1.4e-84 mreD M shape-determining protein
NICMNEDI_02795 1.1e-156 mreC M Involved in formation and maintenance of cell shape
NICMNEDI_02796 1.8e-184 mreB D Rod shape-determining protein MreB
NICMNEDI_02797 2.4e-51 radC E Belongs to the UPF0758 family
NICMNEDI_02798 1.9e-08
NICMNEDI_02800 2.3e-16 K Helix-turn-helix domain
NICMNEDI_02802 5.9e-117 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NICMNEDI_02803 5.4e-58 S Bacteriophage holin family
NICMNEDI_02805 4.5e-08
NICMNEDI_02806 5.4e-83
NICMNEDI_02807 1.3e-58
NICMNEDI_02808 2e-112 mur1 NU Prophage endopeptidase tail
NICMNEDI_02809 4.2e-46 S Phage tail protein
NICMNEDI_02810 2.2e-214 D Phage tail tape measure protein
NICMNEDI_02813 8.1e-28 S Pfam:Phage_TTP_1
NICMNEDI_02814 4.2e-10
NICMNEDI_02815 4.9e-29 S Bacteriophage HK97-gp10, putative tail-component
NICMNEDI_02816 2e-28 S Phage head-tail joining protein
NICMNEDI_02817 2.6e-22 S Phage gp6-like head-tail connector protein
NICMNEDI_02818 2.2e-08
NICMNEDI_02819 4.7e-131 S capsid protein
NICMNEDI_02820 1.1e-72 pi136 S Caudovirus prohead serine protease
NICMNEDI_02821 1.5e-169 S portal protein
NICMNEDI_02823 2.8e-262 terL S Terminase
NICMNEDI_02824 2.5e-59 terS L Terminase, small subunit
NICMNEDI_02825 2e-17 S HNH endonuclease
NICMNEDI_02826 1.5e-09
NICMNEDI_02828 7.9e-48
NICMNEDI_02829 8e-228 KL SNF2 family N-terminal domain
NICMNEDI_02830 6.9e-32 S VRR_NUC
NICMNEDI_02831 0.0 L Virulence-associated protein E
NICMNEDI_02833 1.4e-302 2.7.7.7 L DNA polymerase A domain
NICMNEDI_02834 2.4e-21
NICMNEDI_02835 1.4e-85 S Protein of unknown function (DUF2815)
NICMNEDI_02836 3.1e-27
NICMNEDI_02837 1.4e-164 L Protein of unknown function (DUF2800)
NICMNEDI_02839 1.3e-48
NICMNEDI_02842 2e-08 plcR K helix-turn-helix
NICMNEDI_02843 1.8e-64 S sequence-specific DNA binding
NICMNEDI_02844 3.1e-72 S Pfam:Peptidase_M78
NICMNEDI_02845 8.1e-231 S Recombinase
NICMNEDI_02846 9.8e-68 radC E Belongs to the UPF0758 family
NICMNEDI_02847 1.1e-101 maf D septum formation protein Maf
NICMNEDI_02848 4.1e-165 spoIIB S Sporulation related domain
NICMNEDI_02849 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NICMNEDI_02850 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NICMNEDI_02851 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NICMNEDI_02852 1.6e-25
NICMNEDI_02853 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NICMNEDI_02854 3.1e-192 spoVID M stage VI sporulation protein D
NICMNEDI_02855 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NICMNEDI_02856 6.2e-182 hemB 4.2.1.24 H Belongs to the ALAD family
NICMNEDI_02857 7.9e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NICMNEDI_02858 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NICMNEDI_02859 3.6e-146 hemX O cytochrome C
NICMNEDI_02860 8.6e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NICMNEDI_02861 1.2e-88 ysxD
NICMNEDI_02862 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NICMNEDI_02863 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NICMNEDI_02864 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NICMNEDI_02865 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NICMNEDI_02866 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NICMNEDI_02867 4.3e-186 ysoA H Tetratricopeptide repeat
NICMNEDI_02868 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NICMNEDI_02869 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NICMNEDI_02870 1.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NICMNEDI_02871 7.1e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NICMNEDI_02872 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NICMNEDI_02873 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NICMNEDI_02874 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NICMNEDI_02876 2.8e-76 ysnE K acetyltransferase
NICMNEDI_02877 3.8e-132 ysnF S protein conserved in bacteria
NICMNEDI_02879 4.1e-92 ysnB S Phosphoesterase
NICMNEDI_02880 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NICMNEDI_02881 2e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NICMNEDI_02882 5e-196 gerM S COG5401 Spore germination protein
NICMNEDI_02883 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NICMNEDI_02884 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NICMNEDI_02885 3.3e-30 gerE K Transcriptional regulator
NICMNEDI_02886 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NICMNEDI_02887 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NICMNEDI_02888 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NICMNEDI_02889 2.4e-107 sdhC C succinate dehydrogenase
NICMNEDI_02890 1.2e-79 yslB S Protein of unknown function (DUF2507)
NICMNEDI_02891 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NICMNEDI_02892 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NICMNEDI_02893 2e-52 trxA O Belongs to the thioredoxin family
NICMNEDI_02894 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NICMNEDI_02896 9.3e-178 etfA C Electron transfer flavoprotein
NICMNEDI_02897 1.7e-134 etfB C Electron transfer flavoprotein
NICMNEDI_02898 1.2e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NICMNEDI_02899 4e-99 fadR K Transcriptional regulator
NICMNEDI_02900 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NICMNEDI_02901 7.3e-68 yshE S membrane
NICMNEDI_02902 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NICMNEDI_02903 0.0 polX L COG1796 DNA polymerase IV (family X)
NICMNEDI_02904 3.9e-85 cvpA S membrane protein, required for colicin V production
NICMNEDI_02905 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NICMNEDI_02906 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NICMNEDI_02907 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NICMNEDI_02908 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NICMNEDI_02909 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NICMNEDI_02910 5.8e-32 sspI S Belongs to the SspI family
NICMNEDI_02911 1.5e-203 ysfB KT regulator
NICMNEDI_02912 4e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
NICMNEDI_02913 6.2e-257 glcF C Glycolate oxidase
NICMNEDI_02914 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
NICMNEDI_02915 0.0 cstA T Carbon starvation protein
NICMNEDI_02916 3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NICMNEDI_02917 3.4e-144 araQ G transport system permease
NICMNEDI_02918 4.2e-167 araP G carbohydrate transport
NICMNEDI_02919 1.8e-253 araN G carbohydrate transport
NICMNEDI_02920 2.6e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NICMNEDI_02921 2.5e-144 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NICMNEDI_02922 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NICMNEDI_02923 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NICMNEDI_02924 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NICMNEDI_02925 3.4e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NICMNEDI_02926 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
NICMNEDI_02927 3.5e-67 ysdB S Sigma-w pathway protein YsdB
NICMNEDI_02928 7.5e-45 ysdA S Membrane
NICMNEDI_02929 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NICMNEDI_02930 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NICMNEDI_02931 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NICMNEDI_02933 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NICMNEDI_02934 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NICMNEDI_02935 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
NICMNEDI_02936 0.0 lytS 2.7.13.3 T Histidine kinase
NICMNEDI_02937 2.8e-148 ysaA S HAD-hyrolase-like
NICMNEDI_02938 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NICMNEDI_02940 1.4e-158 ytxC S YtxC-like family
NICMNEDI_02941 4.6e-109 ytxB S SNARE associated Golgi protein
NICMNEDI_02942 2.5e-172 dnaI L Primosomal protein DnaI
NICMNEDI_02943 2.2e-265 dnaB L Membrane attachment protein
NICMNEDI_02944 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NICMNEDI_02945 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NICMNEDI_02946 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NICMNEDI_02947 4.9e-66 ytcD K Transcriptional regulator
NICMNEDI_02948 1.6e-203 ytbD EGP Major facilitator Superfamily
NICMNEDI_02949 1.7e-159 ytbE S reductase
NICMNEDI_02950 6.4e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NICMNEDI_02951 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NICMNEDI_02952 7.8e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NICMNEDI_02953 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NICMNEDI_02954 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NICMNEDI_02955 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_02956 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NICMNEDI_02957 4.1e-242 icd 1.1.1.42 C isocitrate
NICMNEDI_02958 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NICMNEDI_02959 4.7e-71 yeaL S membrane
NICMNEDI_02960 2.6e-192 ytvI S sporulation integral membrane protein YtvI
NICMNEDI_02961 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NICMNEDI_02962 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NICMNEDI_02963 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NICMNEDI_02964 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NICMNEDI_02965 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NICMNEDI_02966 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NICMNEDI_02967 0.0 dnaE 2.7.7.7 L DNA polymerase
NICMNEDI_02968 3.2e-56 ytrH S Sporulation protein YtrH
NICMNEDI_02969 8.2e-69 ytrI
NICMNEDI_02970 9.2e-29
NICMNEDI_02971 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NICMNEDI_02972 2.4e-47 ytpI S YtpI-like protein
NICMNEDI_02973 8e-241 ytoI K transcriptional regulator containing CBS domains
NICMNEDI_02974 1.7e-130 ytkL S Belongs to the UPF0173 family
NICMNEDI_02975 1.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NICMNEDI_02977 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
NICMNEDI_02978 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NICMNEDI_02979 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NICMNEDI_02980 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NICMNEDI_02981 2e-164 ytxK 2.1.1.72 L DNA methylase
NICMNEDI_02982 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NICMNEDI_02983 8.7e-70 ytfJ S Sporulation protein YtfJ
NICMNEDI_02984 8.1e-115 ytfI S Protein of unknown function (DUF2953)
NICMNEDI_02985 2.5e-86 yteJ S RDD family
NICMNEDI_02986 2.3e-179 sppA OU signal peptide peptidase SppA
NICMNEDI_02987 8.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NICMNEDI_02988 0.0 ytcJ S amidohydrolase
NICMNEDI_02989 5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NICMNEDI_02990 2e-29 sspB S spore protein
NICMNEDI_02991 5.6e-86 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NICMNEDI_02992 4.7e-108 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NICMNEDI_02993 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
NICMNEDI_02994 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NICMNEDI_02995 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NICMNEDI_02996 1.7e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NICMNEDI_02997 1e-108 yttP K Transcriptional regulator
NICMNEDI_02998 5.9e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NICMNEDI_02999 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NICMNEDI_03000 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NICMNEDI_03002 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NICMNEDI_03003 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NICMNEDI_03004 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NICMNEDI_03005 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NICMNEDI_03006 2.3e-223 acuC BQ histone deacetylase
NICMNEDI_03007 1.4e-125 motS N Flagellar motor protein
NICMNEDI_03008 2.1e-146 motA N flagellar motor
NICMNEDI_03009 3.8e-182 ccpA K catabolite control protein A
NICMNEDI_03010 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NICMNEDI_03011 5.3e-53 ytxJ O Protein of unknown function (DUF2847)
NICMNEDI_03012 6.6e-17 ytxH S COG4980 Gas vesicle protein
NICMNEDI_03013 1.4e-16 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NICMNEDI_03014 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NICMNEDI_03015 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NICMNEDI_03016 3.7e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NICMNEDI_03017 1.4e-147 ytpQ S Belongs to the UPF0354 family
NICMNEDI_03018 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NICMNEDI_03019 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NICMNEDI_03020 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NICMNEDI_03021 2.2e-51 ytzB S small secreted protein
NICMNEDI_03022 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NICMNEDI_03023 5.1e-148 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NICMNEDI_03024 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NICMNEDI_03025 2e-45 ytzH S YtzH-like protein
NICMNEDI_03026 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NICMNEDI_03027 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NICMNEDI_03028 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NICMNEDI_03029 1.3e-165 ytlQ
NICMNEDI_03030 2.9e-99 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NICMNEDI_03031 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NICMNEDI_03032 2.7e-271 pepV 3.5.1.18 E Dipeptidase
NICMNEDI_03033 7.2e-226 pbuO S permease
NICMNEDI_03034 9.3e-201 ythQ U Bacterial ABC transporter protein EcsB
NICMNEDI_03035 4.8e-131 ythP V ABC transporter
NICMNEDI_03036 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NICMNEDI_03037 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NICMNEDI_03038 5.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NICMNEDI_03039 2.6e-230 ytfP S HI0933-like protein
NICMNEDI_03040 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NICMNEDI_03041 3.1e-26 yteV S Sporulation protein Cse60
NICMNEDI_03042 3.4e-115 yteU S Integral membrane protein
NICMNEDI_03043 5e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NICMNEDI_03044 3.3e-71 yteS G transport
NICMNEDI_03045 1.1e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NICMNEDI_03046 6.4e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NICMNEDI_03047 0.0 ytdP K Transcriptional regulator
NICMNEDI_03048 5.8e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NICMNEDI_03049 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
NICMNEDI_03050 8.1e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NICMNEDI_03051 1.7e-218 bioI 1.14.14.46 C Cytochrome P450
NICMNEDI_03052 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NICMNEDI_03053 7.2e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NICMNEDI_03054 3e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NICMNEDI_03055 1.1e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NICMNEDI_03056 1.5e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NICMNEDI_03057 2.4e-172 ytaP S Acetyl xylan esterase (AXE1)
NICMNEDI_03058 1.5e-189 msmR K Transcriptional regulator
NICMNEDI_03059 8e-246 msmE G Bacterial extracellular solute-binding protein
NICMNEDI_03060 1.8e-167 amyD P ABC transporter
NICMNEDI_03061 4.4e-144 amyC P ABC transporter (permease)
NICMNEDI_03062 4.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NICMNEDI_03063 2.1e-51 ytwF P Sulfurtransferase
NICMNEDI_03064 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NICMNEDI_03065 1.1e-53 ytvB S Protein of unknown function (DUF4257)
NICMNEDI_03066 1.1e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NICMNEDI_03067 6e-211 yttB EGP Major facilitator Superfamily
NICMNEDI_03068 1.1e-42 yttA 2.7.13.3 S Pfam Transposase IS66
NICMNEDI_03069 0.0 bceB V ABC transporter (permease)
NICMNEDI_03070 1.9e-138 bceA V ABC transporter, ATP-binding protein
NICMNEDI_03071 9.9e-183 T PhoQ Sensor
NICMNEDI_03072 2.8e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_03073 4.7e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NICMNEDI_03074 5.9e-126 ytrE V ABC transporter, ATP-binding protein
NICMNEDI_03075 5.3e-149
NICMNEDI_03076 2e-164 P ABC-2 family transporter protein
NICMNEDI_03077 4.2e-161 ytrB P abc transporter atp-binding protein
NICMNEDI_03078 5.1e-66 ytrA K GntR family transcriptional regulator
NICMNEDI_03080 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NICMNEDI_03081 4e-189 yhcC S Fe-S oxidoreductase
NICMNEDI_03082 2.8e-105 ytqB J Putative rRNA methylase
NICMNEDI_03083 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NICMNEDI_03084 4.7e-148 ytpA 3.1.1.5 I Alpha beta hydrolase
NICMNEDI_03085 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NICMNEDI_03086 1.6e-247 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NICMNEDI_03087 0.0 asnB 6.3.5.4 E Asparagine synthase
NICMNEDI_03088 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NICMNEDI_03089 1.5e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NICMNEDI_03090 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NICMNEDI_03091 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NICMNEDI_03092 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NICMNEDI_03093 1.4e-144 ytlC P ABC transporter
NICMNEDI_03094 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NICMNEDI_03095 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NICMNEDI_03096 7e-63 ytkC S Bacteriophage holin family
NICMNEDI_03097 2.1e-76 dps P Belongs to the Dps family
NICMNEDI_03099 1.1e-72 ytkA S YtkA-like
NICMNEDI_03100 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NICMNEDI_03101 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NICMNEDI_03102 3.6e-41 rpmE2 J Ribosomal protein L31
NICMNEDI_03103 1.8e-248 cydA 1.10.3.14 C oxidase, subunit
NICMNEDI_03104 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NICMNEDI_03105 1.1e-24 S Domain of Unknown Function (DUF1540)
NICMNEDI_03106 1.2e-147 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NICMNEDI_03107 3.1e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NICMNEDI_03108 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NICMNEDI_03109 9.7e-169 troA P Belongs to the bacterial solute-binding protein 9 family
NICMNEDI_03110 3.5e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NICMNEDI_03111 3.3e-272 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NICMNEDI_03112 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NICMNEDI_03113 2.2e-151 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NICMNEDI_03114 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NICMNEDI_03115 3.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
NICMNEDI_03116 1.7e-131 dksA T COG1734 DnaK suppressor protein
NICMNEDI_03117 4.3e-152 galU 2.7.7.9 M Nucleotidyl transferase
NICMNEDI_03118 2.1e-241 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NICMNEDI_03119 1.8e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NICMNEDI_03120 3.7e-232 ytcC M Glycosyltransferase Family 4
NICMNEDI_03122 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
NICMNEDI_03123 7.7e-216 cotSA M Glycosyl transferases group 1
NICMNEDI_03124 4.4e-205 cotI S Spore coat protein
NICMNEDI_03125 8.4e-76 tspO T membrane
NICMNEDI_03126 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NICMNEDI_03127 1.2e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NICMNEDI_03128 8.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NICMNEDI_03129 1.2e-195 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NICMNEDI_03130 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NICMNEDI_03139 7.8e-08
NICMNEDI_03140 1.3e-09
NICMNEDI_03147 2e-08
NICMNEDI_03152 3.4e-39 S COG NOG14552 non supervised orthologous group
NICMNEDI_03153 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
NICMNEDI_03154 1.4e-92 M1-753 M FR47-like protein
NICMNEDI_03155 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
NICMNEDI_03156 5.5e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NICMNEDI_03157 1.5e-83 yuaE S DinB superfamily
NICMNEDI_03158 2.5e-106 yuaD
NICMNEDI_03159 1.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
NICMNEDI_03160 1.2e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NICMNEDI_03161 3.6e-94 yuaC K Belongs to the GbsR family
NICMNEDI_03162 2.2e-91 yuaB
NICMNEDI_03163 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NICMNEDI_03164 1.1e-234 ktrB P Potassium
NICMNEDI_03165 1e-38 yiaA S yiaA/B two helix domain
NICMNEDI_03166 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NICMNEDI_03167 8.3e-274 yubD P Major Facilitator Superfamily
NICMNEDI_03168 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NICMNEDI_03170 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NICMNEDI_03171 9.1e-196 yubA S transporter activity
NICMNEDI_03172 4.4e-183 ygjR S Oxidoreductase
NICMNEDI_03173 2.8e-251 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NICMNEDI_03174 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NICMNEDI_03175 1.9e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NICMNEDI_03176 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NICMNEDI_03177 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NICMNEDI_03178 5.1e-239 mcpA NT chemotaxis protein
NICMNEDI_03179 3.2e-294 mcpA NT chemotaxis protein
NICMNEDI_03180 3.6e-221 mcpA NT chemotaxis protein
NICMNEDI_03181 3.2e-225 mcpA NT chemotaxis protein
NICMNEDI_03182 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NICMNEDI_03183 2.3e-35
NICMNEDI_03184 2.1e-72 yugU S Uncharacterised protein family UPF0047
NICMNEDI_03185 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NICMNEDI_03186 1.3e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NICMNEDI_03187 1.4e-116 yugP S Zn-dependent protease
NICMNEDI_03188 2.3e-38
NICMNEDI_03189 5.4e-53 mstX S Membrane-integrating protein Mistic
NICMNEDI_03190 1.1e-181 yugO P COG1226 Kef-type K transport systems
NICMNEDI_03191 6.3e-72 yugN S YugN-like family
NICMNEDI_03193 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NICMNEDI_03194 3.1e-228 yugK C Dehydrogenase
NICMNEDI_03195 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NICMNEDI_03196 1.1e-34 yuzA S Domain of unknown function (DUF378)
NICMNEDI_03197 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NICMNEDI_03198 4.8e-199 yugH 2.6.1.1 E Aminotransferase
NICMNEDI_03199 1.6e-85 alaR K Transcriptional regulator
NICMNEDI_03200 3.8e-156 yugF I Hydrolase
NICMNEDI_03201 5e-38 yugE S Domain of unknown function (DUF1871)
NICMNEDI_03202 1.3e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NICMNEDI_03203 1e-232 T PhoQ Sensor
NICMNEDI_03204 3.3e-70 kapB G Kinase associated protein B
NICMNEDI_03205 1.9e-115 kapD L the KinA pathway to sporulation
NICMNEDI_03207 4.2e-184 yuxJ EGP Major facilitator Superfamily
NICMNEDI_03208 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NICMNEDI_03209 1.1e-68 yuxK S protein conserved in bacteria
NICMNEDI_03210 6.3e-78 yufK S Family of unknown function (DUF5366)
NICMNEDI_03211 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NICMNEDI_03212 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NICMNEDI_03213 6.1e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NICMNEDI_03214 3.2e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NICMNEDI_03215 4.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
NICMNEDI_03216 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NICMNEDI_03217 8.2e-233 maeN C COG3493 Na citrate symporter
NICMNEDI_03218 5e-15
NICMNEDI_03219 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NICMNEDI_03220 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NICMNEDI_03221 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NICMNEDI_03222 1.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NICMNEDI_03223 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NICMNEDI_03224 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NICMNEDI_03225 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NICMNEDI_03226 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NICMNEDI_03227 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NICMNEDI_03228 1.9e-261 comP 2.7.13.3 T Histidine kinase
NICMNEDI_03230 4.7e-142 comQ H Belongs to the FPP GGPP synthase family
NICMNEDI_03232 8.5e-23 yuzC
NICMNEDI_03233 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NICMNEDI_03234 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NICMNEDI_03235 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
NICMNEDI_03236 7.9e-67 yueI S Protein of unknown function (DUF1694)
NICMNEDI_03237 7.4e-39 yueH S YueH-like protein
NICMNEDI_03238 6.6e-31 yueG S Spore germination protein gerPA/gerPF
NICMNEDI_03239 3.2e-190 yueF S transporter activity
NICMNEDI_03240 1.2e-67 S Protein of unknown function (DUF2283)
NICMNEDI_03241 2.9e-24 S Protein of unknown function (DUF2642)
NICMNEDI_03242 1.4e-95 yueE S phosphohydrolase
NICMNEDI_03243 1.1e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NICMNEDI_03244 3.3e-64 yueC S Family of unknown function (DUF5383)
NICMNEDI_03245 0.0 esaA S type VII secretion protein EsaA
NICMNEDI_03246 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NICMNEDI_03247 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NICMNEDI_03248 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NICMNEDI_03249 2.8e-45 esxA S Belongs to the WXG100 family
NICMNEDI_03250 1.8e-226 yukF QT Transcriptional regulator
NICMNEDI_03251 1.8e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NICMNEDI_03252 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NICMNEDI_03253 1.4e-35 mbtH S MbtH-like protein
NICMNEDI_03254 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_03255 2.2e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NICMNEDI_03256 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NICMNEDI_03257 4.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
NICMNEDI_03258 1.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_03259 2.8e-165 besA S Putative esterase
NICMNEDI_03260 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NICMNEDI_03261 3.8e-68 bioY S Biotin biosynthesis protein
NICMNEDI_03262 3.9e-211 yuiF S antiporter
NICMNEDI_03263 7.6e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NICMNEDI_03264 1.2e-77 yuiD S protein conserved in bacteria
NICMNEDI_03265 1.4e-116 yuiC S protein conserved in bacteria
NICMNEDI_03266 8.4e-27 yuiB S Putative membrane protein
NICMNEDI_03267 2.3e-235 yumB 1.6.99.3 C NADH dehydrogenase
NICMNEDI_03268 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
NICMNEDI_03270 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NICMNEDI_03271 5.1e-113 paiB K Putative FMN-binding domain
NICMNEDI_03272 1.5e-70 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NICMNEDI_03273 3.7e-63 erpA S Belongs to the HesB IscA family
NICMNEDI_03274 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NICMNEDI_03275 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NICMNEDI_03276 3.2e-39 yuzB S Belongs to the UPF0349 family
NICMNEDI_03277 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NICMNEDI_03278 3e-56 yuzD S protein conserved in bacteria
NICMNEDI_03279 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NICMNEDI_03280 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NICMNEDI_03281 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NICMNEDI_03282 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NICMNEDI_03283 7.9e-241 hom 1.1.1.3 E homoserine dehydrogenase
NICMNEDI_03284 6.5e-198 yutH S Spore coat protein
NICMNEDI_03285 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NICMNEDI_03286 1.4e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NICMNEDI_03287 1e-75 yutE S Protein of unknown function DUF86
NICMNEDI_03288 9.7e-48 yutD S protein conserved in bacteria
NICMNEDI_03289 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NICMNEDI_03290 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NICMNEDI_03291 1.3e-187 lytH M Peptidase, M23
NICMNEDI_03292 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
NICMNEDI_03293 1.1e-47 yunC S Domain of unknown function (DUF1805)
NICMNEDI_03294 4.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NICMNEDI_03295 2e-141 yunE S membrane transporter protein
NICMNEDI_03296 4.3e-171 yunF S Protein of unknown function DUF72
NICMNEDI_03297 8.2e-60 yunG
NICMNEDI_03298 8.6e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NICMNEDI_03299 2.4e-300 pucR QT COG2508 Regulator of polyketide synthase expression
NICMNEDI_03300 1.5e-201 pbuX F Permease family
NICMNEDI_03301 1.4e-221 pbuX F xanthine
NICMNEDI_03302 7.1e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NICMNEDI_03303 1.5e-53 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NICMNEDI_03305 3.4e-94 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NICMNEDI_03306 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NICMNEDI_03307 2.9e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NICMNEDI_03308 3.1e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NICMNEDI_03309 1.3e-182 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NICMNEDI_03310 5.6e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NICMNEDI_03311 2.4e-231 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NICMNEDI_03312 3.5e-168 bsn L Ribonuclease
NICMNEDI_03313 1.2e-205 msmX P Belongs to the ABC transporter superfamily
NICMNEDI_03314 3.3e-135 yurK K UTRA
NICMNEDI_03315 5.7e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NICMNEDI_03316 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
NICMNEDI_03317 1.2e-155 yurN G Binding-protein-dependent transport system inner membrane component
NICMNEDI_03318 2.7e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NICMNEDI_03319 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NICMNEDI_03320 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NICMNEDI_03321 8.4e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NICMNEDI_03323 1.5e-37
NICMNEDI_03324 2e-287 L Uncharacterized conserved protein (DUF2075)
NICMNEDI_03325 5.5e-53 S MazG-like family
NICMNEDI_03326 3.5e-271 sufB O FeS cluster assembly
NICMNEDI_03327 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NICMNEDI_03328 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NICMNEDI_03329 5e-243 sufD O assembly protein SufD
NICMNEDI_03330 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NICMNEDI_03331 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NICMNEDI_03332 9.4e-147 metQ P Belongs to the NlpA lipoprotein family
NICMNEDI_03333 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NICMNEDI_03334 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NICMNEDI_03335 2.4e-56 yusD S SCP-2 sterol transfer family
NICMNEDI_03336 9.5e-55 traF CO Thioredoxin
NICMNEDI_03337 3.7e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NICMNEDI_03338 1.1e-39 yusG S Protein of unknown function (DUF2553)
NICMNEDI_03339 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NICMNEDI_03340 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NICMNEDI_03341 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NICMNEDI_03342 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NICMNEDI_03343 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NICMNEDI_03344 8.1e-09 S YuzL-like protein
NICMNEDI_03345 5.1e-162 fadM E Proline dehydrogenase
NICMNEDI_03346 5.1e-40
NICMNEDI_03347 5.4e-53 yusN M Coat F domain
NICMNEDI_03348 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
NICMNEDI_03349 1.1e-292 yusP P Major facilitator superfamily
NICMNEDI_03350 2.7e-64 yusQ S Tautomerase enzyme
NICMNEDI_03351 2.5e-53 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_03352 9e-47 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_03353 5.7e-158 yusT K LysR substrate binding domain
NICMNEDI_03354 5.6e-39 yusU S Protein of unknown function (DUF2573)
NICMNEDI_03355 5.1e-153 yusV 3.6.3.34 HP ABC transporter
NICMNEDI_03356 2.5e-66 S YusW-like protein
NICMNEDI_03357 1.2e-300 pepF2 E COG1164 Oligoendopeptidase F
NICMNEDI_03358 1.5e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_03359 2.7e-79 dps P Ferritin-like domain
NICMNEDI_03360 6.2e-236 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NICMNEDI_03361 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_03362 1.7e-249 cssS 2.7.13.3 T PhoQ Sensor
NICMNEDI_03363 4.3e-158 yuxN K Transcriptional regulator
NICMNEDI_03364 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NICMNEDI_03365 3.9e-24 S Protein of unknown function (DUF3970)
NICMNEDI_03366 4.5e-245 gerAA EG Spore germination protein
NICMNEDI_03367 1.3e-196 gerAB E Spore germination protein
NICMNEDI_03368 1.3e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
NICMNEDI_03369 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NICMNEDI_03370 7.9e-186 vraS 2.7.13.3 T Histidine kinase
NICMNEDI_03371 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NICMNEDI_03372 1.6e-120 liaG S Putative adhesin
NICMNEDI_03373 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NICMNEDI_03374 6.2e-61 liaI S membrane
NICMNEDI_03375 1.9e-60 yvqJ EGP Major facilitator Superfamily
NICMNEDI_03376 1.5e-147 yvqJ EGP Major facilitator Superfamily
NICMNEDI_03377 5.5e-101 yvqK 2.5.1.17 S Adenosyltransferase
NICMNEDI_03378 2.5e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NICMNEDI_03379 1.8e-93 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_03380 1.3e-74 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_03381 1.6e-163 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NICMNEDI_03382 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_03383 1.3e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
NICMNEDI_03384 0.0 T PhoQ Sensor
NICMNEDI_03385 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_03386 7.2e-23
NICMNEDI_03387 3.3e-98 yvrI K RNA polymerase
NICMNEDI_03388 2.4e-19 S YvrJ protein family
NICMNEDI_03389 6.8e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
NICMNEDI_03390 1.3e-64 yvrL S Regulatory protein YrvL
NICMNEDI_03391 7.5e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NICMNEDI_03392 7.9e-123 macB V ABC transporter, ATP-binding protein
NICMNEDI_03393 6.9e-175 M Efflux transporter rnd family, mfp subunit
NICMNEDI_03394 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NICMNEDI_03395 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_03396 1.8e-182 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NICMNEDI_03397 1.2e-177 fhuD P ABC transporter
NICMNEDI_03399 4.9e-236 yvsH E Arginine ornithine antiporter
NICMNEDI_03400 6.5e-16 S Small spore protein J (Spore_SspJ)
NICMNEDI_03401 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NICMNEDI_03402 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NICMNEDI_03403 7e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NICMNEDI_03404 6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NICMNEDI_03405 6.9e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NICMNEDI_03406 1.1e-155 yvgN S reductase
NICMNEDI_03407 5.4e-86 yvgO
NICMNEDI_03408 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NICMNEDI_03409 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NICMNEDI_03410 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NICMNEDI_03411 0.0 helD 3.6.4.12 L DNA helicase
NICMNEDI_03413 3.4e-63 yvgT S membrane
NICMNEDI_03414 6.5e-72 bdbC O Required for disulfide bond formation in some proteins
NICMNEDI_03415 1.6e-104 bdbD O Thioredoxin
NICMNEDI_03416 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NICMNEDI_03417 0.0 copA 3.6.3.54 P P-type ATPase
NICMNEDI_03418 5.9e-29 copZ P Copper resistance protein CopZ
NICMNEDI_03419 2.2e-48 csoR S transcriptional
NICMNEDI_03420 2.9e-193 yvaA 1.1.1.371 S Oxidoreductase
NICMNEDI_03421 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NICMNEDI_03422 0.0 yvaC S Fusaric acid resistance protein-like
NICMNEDI_03423 2.8e-72 yvaD S Family of unknown function (DUF5360)
NICMNEDI_03424 1.7e-52 yvaE P Small Multidrug Resistance protein
NICMNEDI_03425 3.3e-98 K Bacterial regulatory proteins, tetR family
NICMNEDI_03426 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_03427 1.8e-15
NICMNEDI_03430 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NICMNEDI_03431 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NICMNEDI_03432 5.6e-143 est 3.1.1.1 S Carboxylesterase
NICMNEDI_03433 2.4e-23 secG U Preprotein translocase subunit SecG
NICMNEDI_03434 3.1e-152 yvaM S Serine aminopeptidase, S33
NICMNEDI_03435 9.8e-36 yvzC K Transcriptional
NICMNEDI_03436 4e-69 K transcriptional
NICMNEDI_03437 5.8e-19 yvaO K Cro/C1-type HTH DNA-binding domain
NICMNEDI_03438 2.2e-54 yodB K transcriptional
NICMNEDI_03439 1.1e-218 NT chemotaxis protein
NICMNEDI_03440 1.4e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NICMNEDI_03441 1.2e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NICMNEDI_03442 4.3e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NICMNEDI_03443 3.4e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NICMNEDI_03444 3.3e-60 yvbF K Belongs to the GbsR family
NICMNEDI_03445 4.3e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NICMNEDI_03446 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NICMNEDI_03447 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NICMNEDI_03448 1.2e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NICMNEDI_03449 3.5e-97 yvbF K Belongs to the GbsR family
NICMNEDI_03450 6.4e-103 yvbG U UPF0056 membrane protein
NICMNEDI_03451 1.9e-112 yvbH S YvbH-like oligomerisation region
NICMNEDI_03452 6.8e-122 exoY M Membrane
NICMNEDI_03453 0.0 tcaA S response to antibiotic
NICMNEDI_03454 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
NICMNEDI_03455 1.6e-12 L Molecular Function DNA binding, Biological Process DNA recombination
NICMNEDI_03457 3.4e-196 3.6.3.27 V Peptidase C39 family
NICMNEDI_03458 4.8e-185 lcnDR2 V Lanthionine synthetase C-like protein
NICMNEDI_03460 1.1e-211 lcnDR2 V Lanthionine synthetase C-like protein
NICMNEDI_03463 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NICMNEDI_03464 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NICMNEDI_03465 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NICMNEDI_03466 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NICMNEDI_03467 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NICMNEDI_03468 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NICMNEDI_03469 4.8e-252 araE EGP Major facilitator Superfamily
NICMNEDI_03470 5.5e-203 araR K transcriptional
NICMNEDI_03471 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NICMNEDI_03472 5.1e-159 yvbU K Transcriptional regulator
NICMNEDI_03473 1.6e-155 yvbV EG EamA-like transporter family
NICMNEDI_03474 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NICMNEDI_03475 4.9e-193 yvbX S Glycosyl hydrolase
NICMNEDI_03476 2.2e-131 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NICMNEDI_03477 1e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NICMNEDI_03478 5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NICMNEDI_03479 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NICMNEDI_03480 1.5e-192 desK 2.7.13.3 T Histidine kinase
NICMNEDI_03481 6.9e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
NICMNEDI_03482 2e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NICMNEDI_03484 4.4e-157 rsbQ S Alpha/beta hydrolase family
NICMNEDI_03485 2e-198 rsbU 3.1.3.3 T response regulator
NICMNEDI_03486 9.8e-252 galA 3.2.1.89 G arabinogalactan
NICMNEDI_03487 0.0 lacA 3.2.1.23 G beta-galactosidase
NICMNEDI_03488 7.2e-150 ganQ P transport
NICMNEDI_03489 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
NICMNEDI_03490 3.7e-227 cycB G COG2182 Maltose-binding periplasmic proteins domains
NICMNEDI_03491 4e-184 lacR K Transcriptional regulator
NICMNEDI_03492 2.3e-112 yvfI K COG2186 Transcriptional regulators
NICMNEDI_03493 2e-305 yvfH C L-lactate permease
NICMNEDI_03494 3.3e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NICMNEDI_03495 1e-31 yvfG S YvfG protein
NICMNEDI_03496 1.3e-184 yvfF GM Exopolysaccharide biosynthesis protein
NICMNEDI_03497 2.4e-217 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NICMNEDI_03498 4.8e-53 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NICMNEDI_03499 3.5e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NICMNEDI_03500 1e-255 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NICMNEDI_03501 1.2e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NICMNEDI_03502 9.2e-203 epsI GM pyruvyl transferase
NICMNEDI_03503 2e-194 epsH GT2 S Glycosyltransferase like family 2
NICMNEDI_03504 4.8e-207 epsG S EpsG family
NICMNEDI_03505 1.9e-217 epsF GT4 M Glycosyl transferases group 1
NICMNEDI_03506 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NICMNEDI_03507 3e-220 epsD GT4 M Glycosyl transferase 4-like
NICMNEDI_03508 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NICMNEDI_03509 8.7e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NICMNEDI_03510 4e-122 ywqC M biosynthesis protein
NICMNEDI_03511 6.3e-76 slr K transcriptional
NICMNEDI_03512 9.3e-264 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NICMNEDI_03513 4.6e-93 padC Q Phenolic acid decarboxylase
NICMNEDI_03514 6.1e-71 MA20_18690 S Protein of unknown function (DUF3237)
NICMNEDI_03515 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NICMNEDI_03516 7.2e-261 pbpE V Beta-lactamase
NICMNEDI_03517 9.3e-66
NICMNEDI_03518 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NICMNEDI_03519 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NICMNEDI_03520 1.8e-295 yveA E amino acid
NICMNEDI_03521 6.3e-105 yvdT K Transcriptional regulator
NICMNEDI_03522 1.5e-50 ykkC P Small Multidrug Resistance protein
NICMNEDI_03523 5.4e-50 sugE P Small Multidrug Resistance protein
NICMNEDI_03524 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
NICMNEDI_03526 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NICMNEDI_03527 9.1e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NICMNEDI_03528 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NICMNEDI_03529 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NICMNEDI_03530 8.3e-157 malA S Protein of unknown function (DUF1189)
NICMNEDI_03531 9.5e-147 malD P transport
NICMNEDI_03532 2.9e-243 malC P COG1175 ABC-type sugar transport systems, permease components
NICMNEDI_03533 4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NICMNEDI_03534 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NICMNEDI_03535 2.6e-172 yvdE K Transcriptional regulator
NICMNEDI_03536 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NICMNEDI_03537 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
NICMNEDI_03538 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NICMNEDI_03539 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NICMNEDI_03540 2.5e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NICMNEDI_03541 0.0 yxdM V ABC transporter (permease)
NICMNEDI_03542 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NICMNEDI_03543 3.9e-139 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NICMNEDI_03544 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_03545 2.8e-31
NICMNEDI_03546 4.6e-140 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NICMNEDI_03547 1.6e-36 crh G Phosphocarrier protein Chr
NICMNEDI_03548 4.1e-170 whiA K May be required for sporulation
NICMNEDI_03549 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NICMNEDI_03550 1.7e-165 rapZ S Displays ATPase and GTPase activities
NICMNEDI_03551 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NICMNEDI_03552 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NICMNEDI_03553 2.8e-98 usp CBM50 M protein conserved in bacteria
NICMNEDI_03554 2.2e-276 S COG0457 FOG TPR repeat
NICMNEDI_03555 0.0 msbA2 3.6.3.44 V ABC transporter
NICMNEDI_03557 0.0
NICMNEDI_03558 1.1e-74
NICMNEDI_03559 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NICMNEDI_03560 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NICMNEDI_03561 7.9e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NICMNEDI_03562 2.8e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NICMNEDI_03563 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NICMNEDI_03564 9.9e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NICMNEDI_03565 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NICMNEDI_03566 1.2e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NICMNEDI_03567 1e-139 yvpB NU protein conserved in bacteria
NICMNEDI_03568 1.3e-117 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NICMNEDI_03569 9.6e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NICMNEDI_03570 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NICMNEDI_03571 3.4e-161 yvoD P COG0370 Fe2 transport system protein B
NICMNEDI_03572 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NICMNEDI_03573 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NICMNEDI_03574 1.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NICMNEDI_03575 1.9e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NICMNEDI_03576 1.8e-133 yvoA K transcriptional
NICMNEDI_03577 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NICMNEDI_03578 9.5e-72 adcR K helix_turn_helix multiple antibiotic resistance protein
NICMNEDI_03579 6.1e-227 cypX 1.14.15.13 C Cytochrome P450
NICMNEDI_03580 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NICMNEDI_03581 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
NICMNEDI_03582 2.7e-203 yvmA EGP Major facilitator Superfamily
NICMNEDI_03583 1.2e-50 yvlD S Membrane
NICMNEDI_03584 2.6e-26 pspB KT PspC domain
NICMNEDI_03585 3.2e-166 yvlB S Putative adhesin
NICMNEDI_03586 1.8e-48 yvlA
NICMNEDI_03587 5.7e-33 yvkN
NICMNEDI_03588 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NICMNEDI_03589 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NICMNEDI_03590 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NICMNEDI_03591 1.2e-30 csbA S protein conserved in bacteria
NICMNEDI_03592 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NICMNEDI_03593 7e-101 yvkB K Transcriptional regulator
NICMNEDI_03594 2.8e-225 yvkA EGP Major facilitator Superfamily
NICMNEDI_03595 7e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NICMNEDI_03596 5.3e-56 swrA S Swarming motility protein
NICMNEDI_03597 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NICMNEDI_03598 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NICMNEDI_03599 2.7e-123 ftsE D cell division ATP-binding protein FtsE
NICMNEDI_03600 3.5e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
NICMNEDI_03601 2.1e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NICMNEDI_03602 2.3e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NICMNEDI_03603 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NICMNEDI_03604 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NICMNEDI_03605 2.8e-66
NICMNEDI_03606 2.5e-08 fliT S bacterial-type flagellum organization
NICMNEDI_03607 6.5e-69 fliS N flagellar protein FliS
NICMNEDI_03608 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NICMNEDI_03609 1.8e-56 flaG N flagellar protein FlaG
NICMNEDI_03610 5.9e-80 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NICMNEDI_03611 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NICMNEDI_03612 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NICMNEDI_03613 5.7e-50 yviE
NICMNEDI_03614 7.8e-155 flgL N Belongs to the bacterial flagellin family
NICMNEDI_03615 2.7e-264 flgK N flagellar hook-associated protein
NICMNEDI_03616 2.4e-78 flgN NOU FlgN protein
NICMNEDI_03617 6.7e-38 flgM KNU Negative regulator of flagellin synthesis
NICMNEDI_03618 7e-74 yvyF S flagellar protein
NICMNEDI_03619 1.2e-126 comFC S Phosphoribosyl transferase domain
NICMNEDI_03620 5.7e-46 comFB S Late competence development protein ComFB
NICMNEDI_03621 6.4e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NICMNEDI_03622 7.3e-155 degV S protein conserved in bacteria
NICMNEDI_03623 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NICMNEDI_03624 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NICMNEDI_03625 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NICMNEDI_03626 6e-163 yvhJ K Transcriptional regulator
NICMNEDI_03627 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NICMNEDI_03628 1.2e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NICMNEDI_03629 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
NICMNEDI_03630 5.1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
NICMNEDI_03631 6.3e-263 tuaE M Teichuronic acid biosynthesis protein
NICMNEDI_03632 6.9e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NICMNEDI_03633 1.5e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NICMNEDI_03634 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NICMNEDI_03635 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NICMNEDI_03636 1.5e-94 M Glycosyltransferase like family 2
NICMNEDI_03637 1.1e-206 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NICMNEDI_03638 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NICMNEDI_03639 1e-11
NICMNEDI_03640 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NICMNEDI_03641 2.1e-213 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NICMNEDI_03642 4.6e-88 M Glycosyltransferase like family 2
NICMNEDI_03643 6.4e-101 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NICMNEDI_03644 1.4e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NICMNEDI_03645 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NICMNEDI_03646 1.9e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NICMNEDI_03647 1e-132 tagG GM Transport permease protein
NICMNEDI_03648 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NICMNEDI_03649 2.2e-238 ggaA M Glycosyltransferase like family 2
NICMNEDI_03650 1.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NICMNEDI_03651 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NICMNEDI_03652 9.2e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NICMNEDI_03653 2.7e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NICMNEDI_03654 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NICMNEDI_03655 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NICMNEDI_03656 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NICMNEDI_03657 2e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NICMNEDI_03658 1.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NICMNEDI_03659 3.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NICMNEDI_03660 3.7e-263 gerBA EG Spore germination protein
NICMNEDI_03661 2.6e-192 gerBB E Spore germination protein
NICMNEDI_03662 2.2e-199 gerAC S Spore germination protein
NICMNEDI_03663 1.3e-246 ywtG EGP Major facilitator Superfamily
NICMNEDI_03664 2.3e-168 ywtF K Transcriptional regulator
NICMNEDI_03665 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NICMNEDI_03666 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NICMNEDI_03667 3.6e-21 ywtC
NICMNEDI_03668 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NICMNEDI_03669 8.6e-70 pgsC S biosynthesis protein
NICMNEDI_03670 5.2e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NICMNEDI_03671 9.3e-178 rbsR K transcriptional
NICMNEDI_03672 1.6e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NICMNEDI_03673 6.9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NICMNEDI_03674 8.6e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NICMNEDI_03675 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NICMNEDI_03676 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NICMNEDI_03677 8.7e-93 batE T Sh3 type 3 domain protein
NICMNEDI_03678 8e-48 ywsA S Protein of unknown function (DUF3892)
NICMNEDI_03679 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NICMNEDI_03680 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NICMNEDI_03681 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NICMNEDI_03682 1.1e-169 alsR K LysR substrate binding domain
NICMNEDI_03683 6.1e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NICMNEDI_03684 4.1e-124 ywrJ
NICMNEDI_03685 3.6e-123 cotB
NICMNEDI_03686 1.9e-208 cotH M Spore Coat
NICMNEDI_03687 3.7e-12
NICMNEDI_03688 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NICMNEDI_03689 5e-54 S Domain of unknown function (DUF4181)
NICMNEDI_03690 2.2e-309 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NICMNEDI_03691 8e-82 ywrC K Transcriptional regulator
NICMNEDI_03692 3.5e-103 ywrB P Chromate transporter
NICMNEDI_03693 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
NICMNEDI_03695 1.7e-96 ywqN S NAD(P)H-dependent
NICMNEDI_03696 2.5e-161 K Transcriptional regulator
NICMNEDI_03697 3.8e-120 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NICMNEDI_03698 3.9e-25
NICMNEDI_03699 3e-82 ywqJ S Pre-toxin TG
NICMNEDI_03700 5.2e-17
NICMNEDI_03701 6.1e-43
NICMNEDI_03702 8.8e-214 ywqJ L nucleic acid phosphodiester bond hydrolysis
NICMNEDI_03703 1.2e-37 ywqI S Family of unknown function (DUF5344)
NICMNEDI_03704 1.3e-19 S Domain of unknown function (DUF5082)
NICMNEDI_03705 8.2e-116 ywqG S Domain of unknown function (DUF1963)
NICMNEDI_03706 6.8e-21 ywqG S Domain of unknown function (DUF1963)
NICMNEDI_03707 3.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NICMNEDI_03708 7.9e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NICMNEDI_03709 4.9e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NICMNEDI_03710 2e-116 ywqC M biosynthesis protein
NICMNEDI_03711 1.2e-17
NICMNEDI_03712 2.3e-306 ywqB S SWIM zinc finger
NICMNEDI_03713 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NICMNEDI_03714 7.4e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NICMNEDI_03715 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NICMNEDI_03716 3.7e-57 ssbB L Single-stranded DNA-binding protein
NICMNEDI_03717 3.8e-66 ywpG
NICMNEDI_03718 1.1e-66 ywpF S YwpF-like protein
NICMNEDI_03719 4e-50 srtA 3.4.22.70 M Sortase family
NICMNEDI_03720 5.4e-145 ywpD T Histidine kinase
NICMNEDI_03721 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NICMNEDI_03722 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NICMNEDI_03723 6.8e-198 S aspartate phosphatase
NICMNEDI_03724 2.6e-141 flhP N flagellar basal body
NICMNEDI_03725 9.9e-125 flhO N flagellar basal body
NICMNEDI_03726 3.5e-180 mbl D Rod shape-determining protein
NICMNEDI_03727 3e-44 spoIIID K Stage III sporulation protein D
NICMNEDI_03728 2.1e-70 ywoH K COG1846 Transcriptional regulators
NICMNEDI_03729 1e-210 ywoG EGP Major facilitator Superfamily
NICMNEDI_03730 3.6e-231 ywoF P Right handed beta helix region
NICMNEDI_03731 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NICMNEDI_03732 1.9e-156 ywoD EGP Major facilitator superfamily
NICMNEDI_03733 1.2e-74 ywoD EGP Major facilitator superfamily
NICMNEDI_03734 4e-104 phzA Q Isochorismatase family
NICMNEDI_03735 7.5e-77
NICMNEDI_03736 4.3e-225 amt P Ammonium transporter
NICMNEDI_03737 1.6e-58 nrgB K Belongs to the P(II) protein family
NICMNEDI_03738 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NICMNEDI_03739 4.4e-71 ywnJ S VanZ like family
NICMNEDI_03740 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NICMNEDI_03741 5.9e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NICMNEDI_03742 2.7e-14 ywnC S Family of unknown function (DUF5362)
NICMNEDI_03743 1.3e-188 spsF 2.5.1.56, 2.7.7.92 M NeuB family
NICMNEDI_03744 2.2e-70 ywnF S Family of unknown function (DUF5392)
NICMNEDI_03745 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NICMNEDI_03746 6.2e-141 mta K transcriptional
NICMNEDI_03747 1.3e-58 ywnC S Family of unknown function (DUF5362)
NICMNEDI_03748 4.8e-114 ywnB S NAD(P)H-binding
NICMNEDI_03749 1.7e-64 ywnA K Transcriptional regulator
NICMNEDI_03750 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NICMNEDI_03751 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NICMNEDI_03752 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NICMNEDI_03753 3.8e-11 csbD K CsbD-like
NICMNEDI_03754 3.8e-84 ywmF S Peptidase M50
NICMNEDI_03756 4.6e-104 S response regulator aspartate phosphatase
NICMNEDI_03757 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NICMNEDI_03758 7.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NICMNEDI_03760 3.9e-119 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NICMNEDI_03761 3.9e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NICMNEDI_03762 4.6e-175 spoIID D Stage II sporulation protein D
NICMNEDI_03763 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NICMNEDI_03764 8.2e-134 ywmB S TATA-box binding
NICMNEDI_03765 1.3e-32 ywzB S membrane
NICMNEDI_03766 4.3e-88 ywmA
NICMNEDI_03767 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NICMNEDI_03768 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NICMNEDI_03769 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NICMNEDI_03770 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NICMNEDI_03771 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NICMNEDI_03772 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NICMNEDI_03773 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NICMNEDI_03774 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NICMNEDI_03775 2.5e-62 atpI S ATP synthase
NICMNEDI_03776 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NICMNEDI_03777 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NICMNEDI_03778 7.2e-95 ywlG S Belongs to the UPF0340 family
NICMNEDI_03779 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NICMNEDI_03780 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NICMNEDI_03781 1.7e-91 mntP P Probably functions as a manganese efflux pump
NICMNEDI_03782 8.1e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NICMNEDI_03783 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NICMNEDI_03784 3e-111 spoIIR S stage II sporulation protein R
NICMNEDI_03785 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
NICMNEDI_03787 1.2e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NICMNEDI_03788 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NICMNEDI_03789 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NICMNEDI_03790 7.8e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NICMNEDI_03791 8.6e-160 ywkB S Membrane transport protein
NICMNEDI_03792 0.0 sfcA 1.1.1.38 C malic enzyme
NICMNEDI_03793 7e-104 tdk 2.7.1.21 F thymidine kinase
NICMNEDI_03794 1.1e-32 rpmE J Binds the 23S rRNA
NICMNEDI_03795 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NICMNEDI_03796 1.2e-163 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NICMNEDI_03797 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NICMNEDI_03798 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NICMNEDI_03799 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NICMNEDI_03800 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NICMNEDI_03801 1.8e-90 ywjG S Domain of unknown function (DUF2529)
NICMNEDI_03802 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NICMNEDI_03803 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NICMNEDI_03804 6.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NICMNEDI_03805 0.0 fadF C COG0247 Fe-S oxidoreductase
NICMNEDI_03806 1.2e-219 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NICMNEDI_03807 7.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NICMNEDI_03808 2.7e-42 ywjC
NICMNEDI_03809 2.4e-95 ywjB H RibD C-terminal domain
NICMNEDI_03810 0.0 ywjA V ABC transporter
NICMNEDI_03811 9.3e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NICMNEDI_03812 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
NICMNEDI_03813 3.1e-93 narJ 1.7.5.1 C nitrate reductase
NICMNEDI_03814 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
NICMNEDI_03815 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NICMNEDI_03816 2e-85 arfM T cyclic nucleotide binding
NICMNEDI_03817 5.3e-138 ywiC S YwiC-like protein
NICMNEDI_03818 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NICMNEDI_03819 1.3e-154 narK P COG2223 Nitrate nitrite transporter
NICMNEDI_03820 3.5e-50 narK P COG2223 Nitrate nitrite transporter
NICMNEDI_03821 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NICMNEDI_03822 4.7e-73 ywiB S protein conserved in bacteria
NICMNEDI_03823 1e-07 S Bacteriocin subtilosin A
NICMNEDI_03824 4.9e-270 C Fe-S oxidoreductases
NICMNEDI_03826 3.3e-132 cbiO V ABC transporter
NICMNEDI_03827 1.6e-186 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NICMNEDI_03828 5.5e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
NICMNEDI_03829 1.7e-248 L Peptidase, M16
NICMNEDI_03831 6.2e-244 ywhL CO amine dehydrogenase activity
NICMNEDI_03832 3e-190 ywhK CO amine dehydrogenase activity
NICMNEDI_03833 8.9e-79 S aspartate phosphatase
NICMNEDI_03835 1.2e-49 ywhH S Aminoacyl-tRNA editing domain
NICMNEDI_03836 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NICMNEDI_03837 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NICMNEDI_03838 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NICMNEDI_03839 3.6e-49
NICMNEDI_03840 3.4e-94 ywhD S YwhD family
NICMNEDI_03841 5.1e-119 ywhC S Peptidase family M50
NICMNEDI_03842 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NICMNEDI_03843 9.5e-71 ywhA K Transcriptional regulator
NICMNEDI_03844 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NICMNEDI_03846 1e-238 mmr U Major Facilitator Superfamily
NICMNEDI_03847 5.3e-78 yffB K Transcriptional regulator
NICMNEDI_03848 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NICMNEDI_03849 2.1e-254 ywfO S COG1078 HD superfamily phosphohydrolases
NICMNEDI_03850 3.1e-36 ywzC S Belongs to the UPF0741 family
NICMNEDI_03851 5.1e-110 rsfA_1
NICMNEDI_03852 5.7e-158 ywfM EG EamA-like transporter family
NICMNEDI_03853 2.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NICMNEDI_03854 1.1e-156 cysL K Transcriptional regulator
NICMNEDI_03855 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NICMNEDI_03856 1.1e-146 ywfI C May function as heme-dependent peroxidase
NICMNEDI_03857 5.4e-136 IQ Enoyl-(Acyl carrier protein) reductase
NICMNEDI_03858 1.6e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
NICMNEDI_03859 7.3e-209 bacE EGP Major facilitator Superfamily
NICMNEDI_03860 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NICMNEDI_03861 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NICMNEDI_03862 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NICMNEDI_03863 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NICMNEDI_03864 1.7e-205 ywfA EGP Major facilitator Superfamily
NICMNEDI_03865 6.3e-249 lysP E amino acid
NICMNEDI_03866 0.0 rocB E arginine degradation protein
NICMNEDI_03867 3.5e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NICMNEDI_03868 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NICMNEDI_03869 9.8e-77
NICMNEDI_03870 6.7e-86 spsL 5.1.3.13 M Spore Coat
NICMNEDI_03871 1.3e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NICMNEDI_03872 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NICMNEDI_03873 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NICMNEDI_03874 1.6e-188 spsG M Spore Coat
NICMNEDI_03875 3.5e-129 spsF M Spore Coat
NICMNEDI_03876 3.2e-214 spsE 2.5.1.56 M acid synthase
NICMNEDI_03877 4e-164 spsD 2.3.1.210 K Spore Coat
NICMNEDI_03878 2.1e-224 spsC E Belongs to the DegT DnrJ EryC1 family
NICMNEDI_03879 4.9e-265 spsB M Capsule polysaccharide biosynthesis protein
NICMNEDI_03880 9.1e-144 spsA M Spore Coat
NICMNEDI_03881 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NICMNEDI_03882 4.3e-59 ywdK S small membrane protein
NICMNEDI_03883 8.3e-238 ywdJ F Xanthine uracil
NICMNEDI_03884 1.7e-48 ywdI S Family of unknown function (DUF5327)
NICMNEDI_03885 2.1e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NICMNEDI_03886 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NICMNEDI_03887 5.2e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
NICMNEDI_03889 1.4e-113 ywdD
NICMNEDI_03890 1.3e-57 pex K Transcriptional regulator PadR-like family
NICMNEDI_03891 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NICMNEDI_03892 2e-28 ywdA
NICMNEDI_03893 1e-294 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NICMNEDI_03894 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NICMNEDI_03895 1e-139 focA P Formate/nitrite transporter
NICMNEDI_03896 7e-150 sacT K transcriptional antiterminator
NICMNEDI_03898 0.0 vpr O Belongs to the peptidase S8 family
NICMNEDI_03899 1.2e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NICMNEDI_03900 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NICMNEDI_03901 2.9e-202 rodA D Belongs to the SEDS family
NICMNEDI_03902 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NICMNEDI_03903 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NICMNEDI_03904 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NICMNEDI_03905 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NICMNEDI_03906 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NICMNEDI_03907 1e-35 ywzA S membrane
NICMNEDI_03908 1.2e-301 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NICMNEDI_03909 1e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NICMNEDI_03910 9.5e-60 gtcA S GtrA-like protein
NICMNEDI_03911 1.1e-121 ywcC K transcriptional regulator
NICMNEDI_03913 1.4e-47 ywcB S Protein of unknown function, DUF485
NICMNEDI_03914 1.2e-267 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NICMNEDI_03915 8.1e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NICMNEDI_03916 3.3e-180 ywbN P Dyp-type peroxidase family protein
NICMNEDI_03917 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
NICMNEDI_03918 2.9e-252 P COG0672 High-affinity Fe2 Pb2 permease
NICMNEDI_03919 1.7e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NICMNEDI_03920 5.3e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NICMNEDI_03921 4.3e-153 ywbI K Transcriptional regulator
NICMNEDI_03922 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NICMNEDI_03923 2.3e-111 ywbG M effector of murein hydrolase
NICMNEDI_03924 4.3e-209 ywbF EGP Major facilitator Superfamily
NICMNEDI_03925 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
NICMNEDI_03926 5.4e-220 ywbD 2.1.1.191 J Methyltransferase
NICMNEDI_03927 4.4e-67 ywbC 4.4.1.5 E glyoxalase
NICMNEDI_03928 7e-124 ywbB S Protein of unknown function (DUF2711)
NICMNEDI_03929 1.3e-63 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NICMNEDI_03930 2.9e-149 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NICMNEDI_03931 7.5e-272 epr 3.4.21.62 O Belongs to the peptidase S8 family
NICMNEDI_03932 2.6e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NICMNEDI_03933 1.2e-152 sacY K transcriptional antiterminator
NICMNEDI_03934 2.6e-168 gspA M General stress
NICMNEDI_03935 3e-125 ywaF S Integral membrane protein
NICMNEDI_03936 4e-87 ywaE K Transcriptional regulator
NICMNEDI_03937 1.1e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NICMNEDI_03938 1.1e-237 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NICMNEDI_03939 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NICMNEDI_03940 2.1e-166 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NICMNEDI_03941 2.5e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_03942 1.2e-232 dltB M membrane protein involved in D-alanine export
NICMNEDI_03943 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICMNEDI_03944 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NICMNEDI_03945 4.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_03946 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NICMNEDI_03947 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NICMNEDI_03948 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NICMNEDI_03949 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NICMNEDI_03950 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NICMNEDI_03951 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NICMNEDI_03952 1.1e-19 yxzF
NICMNEDI_03953 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NICMNEDI_03954 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NICMNEDI_03955 8.5e-199 yxlH EGP Major facilitator Superfamily
NICMNEDI_03956 6.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NICMNEDI_03957 9.7e-166 yxlF V ABC transporter, ATP-binding protein
NICMNEDI_03958 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
NICMNEDI_03959 2.2e-28
NICMNEDI_03960 8.1e-46 yxlC S Family of unknown function (DUF5345)
NICMNEDI_03961 8.4e-88 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NICMNEDI_03962 6.6e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NICMNEDI_03963 1.6e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NICMNEDI_03964 0.0 cydD V ATP-binding protein
NICMNEDI_03965 3.5e-248 cydD V ATP-binding
NICMNEDI_03966 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NICMNEDI_03967 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
NICMNEDI_03968 2.1e-228 cimH C COG3493 Na citrate symporter
NICMNEDI_03969 3.3e-308 3.4.24.84 O Peptidase family M48
NICMNEDI_03971 4.3e-155 yxkH G Polysaccharide deacetylase
NICMNEDI_03974 1e-08 P transporter
NICMNEDI_03975 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NICMNEDI_03976 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
NICMNEDI_03977 1.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NICMNEDI_03978 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NICMNEDI_03979 1.3e-74 yxkC S Domain of unknown function (DUF4352)
NICMNEDI_03980 3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NICMNEDI_03981 1.3e-76 S Protein of unknown function (DUF1453)
NICMNEDI_03982 6.1e-187 yxjM T Signal transduction histidine kinase
NICMNEDI_03983 3.7e-114 K helix_turn_helix, Lux Regulon
NICMNEDI_03984 4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NICMNEDI_03987 3.2e-86 yxjI S LURP-one-related
NICMNEDI_03988 4.3e-219 yxjG 2.1.1.14 E Methionine synthase
NICMNEDI_03989 1.5e-216 yxjG 2.1.1.14 E Methionine synthase
NICMNEDI_03990 3.1e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NICMNEDI_03991 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NICMNEDI_03992 5.9e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NICMNEDI_03993 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NICMNEDI_03994 7.3e-155 rlmA 2.1.1.187 Q Methyltransferase domain
NICMNEDI_03995 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NICMNEDI_03996 6.1e-104 T Domain of unknown function (DUF4163)
NICMNEDI_03997 1.1e-46 yxiS
NICMNEDI_03998 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NICMNEDI_03999 6.6e-224 citH C Citrate transporter
NICMNEDI_04000 6.1e-142 exoK GH16 M licheninase activity
NICMNEDI_04001 8.3e-151 licT K transcriptional antiterminator
NICMNEDI_04002 4e-111
NICMNEDI_04003 7.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
NICMNEDI_04004 8.7e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NICMNEDI_04005 8e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NICMNEDI_04008 7.7e-43 yxiJ S YxiJ-like protein
NICMNEDI_04009 4.3e-83 yxiI S Protein of unknown function (DUF2716)
NICMNEDI_04010 1e-135
NICMNEDI_04011 7.4e-14
NICMNEDI_04012 0.0 wapA M COG3209 Rhs family protein
NICMNEDI_04013 9.6e-164 yxxF EG EamA-like transporter family
NICMNEDI_04014 5.4e-72 yxiE T Belongs to the universal stress protein A family
NICMNEDI_04015 2.1e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NICMNEDI_04016 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NICMNEDI_04017 3.3e-32
NICMNEDI_04018 1.8e-136 S nuclease activity
NICMNEDI_04019 4.7e-39 yxiC S Family of unknown function (DUF5344)
NICMNEDI_04020 4.6e-21 S Domain of unknown function (DUF5082)
NICMNEDI_04021 0.0 L HKD family nuclease
NICMNEDI_04022 3.5e-59 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NICMNEDI_04023 6.1e-166 L Protein of unknown function (DUF2726)
NICMNEDI_04024 1.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NICMNEDI_04025 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NICMNEDI_04026 1.5e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
NICMNEDI_04027 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NICMNEDI_04028 1.8e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NICMNEDI_04029 1.1e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NICMNEDI_04030 1.1e-202 lysP E amino acid
NICMNEDI_04031 2.1e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NICMNEDI_04032 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NICMNEDI_04033 1.7e-114 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NICMNEDI_04034 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NICMNEDI_04035 2e-152 yxxB S Domain of Unknown Function (DUF1206)
NICMNEDI_04036 4.6e-197 eutH E Ethanolamine utilisation protein, EutH
NICMNEDI_04037 5.2e-248 yxeQ S MmgE/PrpD family
NICMNEDI_04038 2.7e-213 yxeP 3.5.1.47 E hydrolase activity
NICMNEDI_04039 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NICMNEDI_04040 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
NICMNEDI_04041 7.2e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NICMNEDI_04042 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NICMNEDI_04043 4.9e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NICMNEDI_04044 1.7e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NICMNEDI_04045 5.8e-149 yidA S hydrolases of the HAD superfamily
NICMNEDI_04048 1.3e-20 yxeE
NICMNEDI_04049 5.6e-16 yxeD
NICMNEDI_04050 1.4e-68
NICMNEDI_04051 1.9e-175 fhuD P ABC transporter
NICMNEDI_04052 5.9e-58 yxeA S Protein of unknown function (DUF1093)
NICMNEDI_04053 0.0 yxdM V ABC transporter (permease)
NICMNEDI_04054 2.3e-139 yxdL V ABC transporter, ATP-binding protein
NICMNEDI_04055 4e-181 T PhoQ Sensor
NICMNEDI_04056 4.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_04057 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NICMNEDI_04058 5.6e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NICMNEDI_04059 8.6e-167 iolH G Xylose isomerase-like TIM barrel
NICMNEDI_04060 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NICMNEDI_04061 8.6e-235 iolF EGP Major facilitator Superfamily
NICMNEDI_04062 1.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NICMNEDI_04063 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NICMNEDI_04064 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NICMNEDI_04065 7.8e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NICMNEDI_04066 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NICMNEDI_04067 4.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NICMNEDI_04068 2.4e-175 iolS C Aldo keto reductase
NICMNEDI_04070 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NICMNEDI_04071 1.3e-244 csbC EGP Major facilitator Superfamily
NICMNEDI_04072 0.0 htpG O Molecular chaperone. Has ATPase activity
NICMNEDI_04074 1.2e-149 IQ Enoyl-(Acyl carrier protein) reductase
NICMNEDI_04075 6.2e-197 yxbF K Bacterial regulatory proteins, tetR family
NICMNEDI_04076 2.2e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NICMNEDI_04077 1.4e-30 yxaI S membrane protein domain
NICMNEDI_04078 2e-92 S PQQ-like domain
NICMNEDI_04079 3.7e-62 S Family of unknown function (DUF5391)
NICMNEDI_04080 1.4e-75 yxaI S membrane protein domain
NICMNEDI_04081 6e-227 P Protein of unknown function (DUF418)
NICMNEDI_04082 7.9e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
NICMNEDI_04083 1.3e-99 yxaF K Transcriptional regulator
NICMNEDI_04084 4.4e-197 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NICMNEDI_04085 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NICMNEDI_04086 1.7e-48 S LrgA family
NICMNEDI_04087 2.6e-118 yxaC M effector of murein hydrolase
NICMNEDI_04088 1.4e-192 yxaB GM Polysaccharide pyruvyl transferase
NICMNEDI_04089 4.7e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NICMNEDI_04090 2.8e-126 gntR K transcriptional
NICMNEDI_04091 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NICMNEDI_04092 1.6e-138 gntP EG COG2610 H gluconate symporter and related permeases
NICMNEDI_04093 1.9e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NICMNEDI_04094 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NICMNEDI_04095 7.2e-286 ahpF O Alkyl hydroperoxide reductase
NICMNEDI_04096 9.5e-189 wgaE S Polysaccharide pyruvyl transferase
NICMNEDI_04097 7e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NICMNEDI_04098 1.3e-125 yydK K Transcriptional regulator
NICMNEDI_04099 7.6e-13
NICMNEDI_04100 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NICMNEDI_04102 3.8e-163 3.6.4.12 L UvrD/REP helicase N-terminal domain
NICMNEDI_04103 4e-263 L AAA ATPase domain
NICMNEDI_04104 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NICMNEDI_04105 1.1e-09 S YyzF-like protein
NICMNEDI_04106 1.3e-64
NICMNEDI_04107 1.9e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NICMNEDI_04109 1.5e-31 yycQ S Protein of unknown function (DUF2651)
NICMNEDI_04110 2.4e-204 yycP
NICMNEDI_04111 3.5e-129 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NICMNEDI_04112 1.1e-83 yycN 2.3.1.128 K Acetyltransferase
NICMNEDI_04113 1.5e-187 S aspartate phosphatase
NICMNEDI_04115 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NICMNEDI_04116 1.6e-260 rocE E amino acid
NICMNEDI_04117 4.4e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NICMNEDI_04118 6.4e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NICMNEDI_04119 1.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NICMNEDI_04120 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NICMNEDI_04121 7.3e-155 yycI S protein conserved in bacteria
NICMNEDI_04122 1.5e-258 yycH S protein conserved in bacteria
NICMNEDI_04123 0.0 vicK 2.7.13.3 T Histidine kinase
NICMNEDI_04124 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICMNEDI_04129 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NICMNEDI_04130 1.7e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NICMNEDI_04131 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NICMNEDI_04132 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NICMNEDI_04134 1.9e-15 yycC K YycC-like protein
NICMNEDI_04135 8.4e-221 yeaN P COG2807 Cyanate permease
NICMNEDI_04136 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NICMNEDI_04137 2.8e-67 rplI J binds to the 23S rRNA
NICMNEDI_04138 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NICMNEDI_04139 2.9e-160 yybS S membrane
NICMNEDI_04141 3.9e-84 cotF M Spore coat protein
NICMNEDI_04142 1.4e-68 ydeP3 K Transcriptional regulator
NICMNEDI_04143 4.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NICMNEDI_04144 1.1e-69
NICMNEDI_04146 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NICMNEDI_04147 4.3e-111 K TipAS antibiotic-recognition domain
NICMNEDI_04148 6.3e-124
NICMNEDI_04149 5.9e-67 yybH S SnoaL-like domain
NICMNEDI_04150 6.2e-122 yybG S Pentapeptide repeat-containing protein
NICMNEDI_04151 1.4e-215 ynfM EGP Major facilitator Superfamily
NICMNEDI_04152 6.9e-164 yybE K Transcriptional regulator
NICMNEDI_04153 3.2e-77 yjcF S Acetyltransferase (GNAT) domain
NICMNEDI_04154 8e-74 yybC
NICMNEDI_04155 7.3e-126 S Metallo-beta-lactamase superfamily
NICMNEDI_04156 5.6e-77 yybA 2.3.1.57 K transcriptional
NICMNEDI_04157 2e-71 yjcF S Acetyltransferase (GNAT) domain
NICMNEDI_04158 5e-97 yyaS S Membrane
NICMNEDI_04159 8.4e-93 yyaR K Acetyltransferase (GNAT) domain
NICMNEDI_04160 3.5e-66 yyaQ S YjbR
NICMNEDI_04161 3.8e-107 yyaP 1.5.1.3 H RibD C-terminal domain
NICMNEDI_04163 1.7e-42 L Recombinase
NICMNEDI_04165 7.8e-82 E Transglutaminase-like superfamily
NICMNEDI_04166 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NICMNEDI_04167 4.4e-166 yyaK S CAAX protease self-immunity
NICMNEDI_04168 8.8e-243 EGP Major facilitator superfamily
NICMNEDI_04169 9.6e-95 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NICMNEDI_04170 1.5e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NICMNEDI_04171 1.8e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NICMNEDI_04172 4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
NICMNEDI_04173 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NICMNEDI_04174 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NICMNEDI_04175 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NICMNEDI_04176 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NICMNEDI_04177 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NICMNEDI_04178 2.3e-33 yyzM S protein conserved in bacteria
NICMNEDI_04179 8.1e-177 yyaD S Membrane
NICMNEDI_04180 2.8e-111 yyaC S Sporulation protein YyaC
NICMNEDI_04181 2.1e-149 spo0J K Belongs to the ParB family
NICMNEDI_04182 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NICMNEDI_04183 7.4e-74 S Bacterial PH domain
NICMNEDI_04184 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NICMNEDI_04185 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NICMNEDI_04186 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NICMNEDI_04187 3.5e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NICMNEDI_04188 6.5e-108 jag S single-stranded nucleic acid binding R3H
NICMNEDI_04189 1.9e-117 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NICMNEDI_04190 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)