ORF_ID e_value Gene_name EC_number CAZy COGs Description
OFLKEHFF_00001 8.9e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OFLKEHFF_00002 2.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OFLKEHFF_00003 2.4e-33 yaaA S S4 domain
OFLKEHFF_00004 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OFLKEHFF_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
OFLKEHFF_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OFLKEHFF_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OFLKEHFF_00008 2.2e-38 S COG NOG14552 non supervised orthologous group
OFLKEHFF_00011 1e-176 yaaC S YaaC-like Protein
OFLKEHFF_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OFLKEHFF_00013 3.1e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OFLKEHFF_00014 6.3e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OFLKEHFF_00015 4.7e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OFLKEHFF_00016 9.9e-204 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OFLKEHFF_00017 4e-196 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OFLKEHFF_00018 1.3e-09
OFLKEHFF_00019 2.3e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
OFLKEHFF_00020 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
OFLKEHFF_00021 1.6e-206 yaaH M Glycoside Hydrolase Family
OFLKEHFF_00022 2.5e-95 yaaI Q COG1335 Amidases related to nicotinamidase
OFLKEHFF_00023 4.7e-82 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OFLKEHFF_00024 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OFLKEHFF_00025 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OFLKEHFF_00026 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OFLKEHFF_00027 1e-31 yaaL S Protein of unknown function (DUF2508)
OFLKEHFF_00028 2.1e-36 bofA S Sigma-K factor-processing regulatory protein BofA
OFLKEHFF_00029 2.2e-38 S COG NOG14552 non supervised orthologous group
OFLKEHFF_00032 4.2e-29 csfB S Inhibitor of sigma-G Gin
OFLKEHFF_00033 1.4e-99 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
OFLKEHFF_00034 2.1e-178 yaaN P Belongs to the TelA family
OFLKEHFF_00035 3.9e-257 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
OFLKEHFF_00036 4.6e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OFLKEHFF_00037 7.5e-55 yaaQ S protein conserved in bacteria
OFLKEHFF_00038 7.6e-71 yaaR S protein conserved in bacteria
OFLKEHFF_00039 1.2e-174 holB 2.7.7.7 L DNA polymerase III
OFLKEHFF_00040 3.3e-144 yaaT S stage 0 sporulation protein
OFLKEHFF_00041 5e-36 yabA L Involved in initiation control of chromosome replication
OFLKEHFF_00042 4.6e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
OFLKEHFF_00043 4e-47 yazA L endonuclease containing a URI domain
OFLKEHFF_00044 4.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OFLKEHFF_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
OFLKEHFF_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OFLKEHFF_00047 2.9e-142 tatD L hydrolase, TatD
OFLKEHFF_00048 2.2e-214 rpfB GH23 T protein conserved in bacteria
OFLKEHFF_00049 2.3e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OFLKEHFF_00050 5.7e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OFLKEHFF_00051 1.1e-124 yabG S peptidase
OFLKEHFF_00052 7.8e-39 veg S protein conserved in bacteria
OFLKEHFF_00053 2.9e-27 sspF S DNA topological change
OFLKEHFF_00054 7.8e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OFLKEHFF_00055 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OFLKEHFF_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
OFLKEHFF_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OFLKEHFF_00058 6.6e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OFLKEHFF_00059 2.7e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OFLKEHFF_00060 2.8e-103 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OFLKEHFF_00061 1.2e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OFLKEHFF_00062 6.9e-39 yabK S Peptide ABC transporter permease
OFLKEHFF_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OFLKEHFF_00064 2e-89 spoVT K stage V sporulation protein
OFLKEHFF_00065 7e-268 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFLKEHFF_00066 8.3e-271 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OFLKEHFF_00067 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OFLKEHFF_00068 4.3e-49 yabP S Sporulation protein YabP
OFLKEHFF_00069 3e-100 yabQ S spore cortex biosynthesis protein
OFLKEHFF_00070 2e-56 divIC D Septum formation initiator
OFLKEHFF_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
OFLKEHFF_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
OFLKEHFF_00075 1.2e-121 yabS S protein containing a von Willebrand factor type A (vWA) domain
OFLKEHFF_00076 1.2e-180 KLT serine threonine protein kinase
OFLKEHFF_00077 6.1e-263 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OFLKEHFF_00078 2.5e-92 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OFLKEHFF_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OFLKEHFF_00080 3.5e-137 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OFLKEHFF_00081 1.6e-160 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OFLKEHFF_00082 4.4e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
OFLKEHFF_00083 4.1e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OFLKEHFF_00084 5.7e-261 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OFLKEHFF_00085 2.2e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
OFLKEHFF_00086 8.5e-151 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
OFLKEHFF_00087 5.3e-153 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OFLKEHFF_00088 2.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OFLKEHFF_00089 1.5e-86 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OFLKEHFF_00090 7.1e-28 yazB K transcriptional
OFLKEHFF_00091 1.6e-180 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OFLKEHFF_00092 1.8e-284 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OFLKEHFF_00093 2.2e-38 S COG NOG14552 non supervised orthologous group
OFLKEHFF_00095 1.3e-07
OFLKEHFF_00098 2e-08
OFLKEHFF_00103 2.2e-38 S COG NOG14552 non supervised orthologous group
OFLKEHFF_00104 7.5e-77 ctsR K Belongs to the CtsR family
OFLKEHFF_00105 1.4e-60 mcsA 2.7.14.1 S protein with conserved CXXC pairs
OFLKEHFF_00106 2.7e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OFLKEHFF_00107 0.0 clpC O Belongs to the ClpA ClpB family
OFLKEHFF_00108 3.9e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OFLKEHFF_00109 4.2e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OFLKEHFF_00110 5.2e-185 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
OFLKEHFF_00111 2.8e-120 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OFLKEHFF_00112 3.5e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OFLKEHFF_00113 1.1e-275 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OFLKEHFF_00114 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
OFLKEHFF_00115 9e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OFLKEHFF_00116 5.7e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OFLKEHFF_00117 2.2e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OFLKEHFF_00118 1.8e-87 yacP S RNA-binding protein containing a PIN domain
OFLKEHFF_00119 4.4e-115 sigH K Belongs to the sigma-70 factor family
OFLKEHFF_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OFLKEHFF_00121 1.2e-95 nusG K Participates in transcription elongation, termination and antitermination
OFLKEHFF_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OFLKEHFF_00123 9.4e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OFLKEHFF_00124 9.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OFLKEHFF_00125 2.8e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OFLKEHFF_00126 6.3e-108 rsmC 2.1.1.172 J Methyltransferase
OFLKEHFF_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFLKEHFF_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFLKEHFF_00129 2.7e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
OFLKEHFF_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OFLKEHFF_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OFLKEHFF_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OFLKEHFF_00133 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OFLKEHFF_00134 4.9e-171 ybaC 3.4.11.5 S Alpha/beta hydrolase family
OFLKEHFF_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OFLKEHFF_00136 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OFLKEHFF_00137 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
OFLKEHFF_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OFLKEHFF_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OFLKEHFF_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OFLKEHFF_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OFLKEHFF_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OFLKEHFF_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OFLKEHFF_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OFLKEHFF_00145 1.3e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OFLKEHFF_00146 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OFLKEHFF_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OFLKEHFF_00148 3.9e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OFLKEHFF_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OFLKEHFF_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OFLKEHFF_00151 1.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OFLKEHFF_00152 2.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OFLKEHFF_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OFLKEHFF_00154 1.9e-23 rpmD J Ribosomal protein L30
OFLKEHFF_00155 4.1e-72 rplO J binds to the 23S rRNA
OFLKEHFF_00156 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OFLKEHFF_00157 9.8e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OFLKEHFF_00158 9.1e-141 map 3.4.11.18 E Methionine aminopeptidase
OFLKEHFF_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OFLKEHFF_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OFLKEHFF_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OFLKEHFF_00162 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OFLKEHFF_00163 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OFLKEHFF_00164 4.7e-58 rplQ J Ribosomal protein L17
OFLKEHFF_00165 1.4e-153 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OFLKEHFF_00166 2.4e-145 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OFLKEHFF_00167 5e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OFLKEHFF_00168 5.9e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OFLKEHFF_00169 7.1e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OFLKEHFF_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OFLKEHFF_00171 7.9e-140 ybaJ Q Methyltransferase domain
OFLKEHFF_00172 3.5e-15 ybaJ Q Methyltransferase domain
OFLKEHFF_00173 3.6e-76 ybaK S Protein of unknown function (DUF2521)
OFLKEHFF_00174 1.8e-130 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFLKEHFF_00175 8.5e-193 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OFLKEHFF_00176 1.7e-75 gerD
OFLKEHFF_00177 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OFLKEHFF_00178 2.4e-128 pdaB 3.5.1.104 G Polysaccharide deacetylase
OFLKEHFF_00179 2.2e-38 S COG NOG14552 non supervised orthologous group
OFLKEHFF_00182 1.6e-08
OFLKEHFF_00185 2.2e-38 S COG NOG14552 non supervised orthologous group
OFLKEHFF_00186 2.1e-211 glcP G Major Facilitator Superfamily
OFLKEHFF_00187 1.8e-245 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OFLKEHFF_00188 3.2e-175 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
OFLKEHFF_00189 2.2e-201 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
OFLKEHFF_00190 9.7e-224 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
OFLKEHFF_00191 3.2e-170 ybaS 1.1.1.58 S Na -dependent transporter
OFLKEHFF_00192 1.5e-103 ybbA S Putative esterase
OFLKEHFF_00193 1.8e-176 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFLKEHFF_00194 6.9e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFLKEHFF_00195 1.7e-168 feuA P Iron-uptake system-binding protein
OFLKEHFF_00196 1.7e-290 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
OFLKEHFF_00197 1.6e-230 ybbC 3.2.1.52 S protein conserved in bacteria
OFLKEHFF_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
OFLKEHFF_00199 2.6e-236 yfeW 3.4.16.4 V Belongs to the UPF0214 family
OFLKEHFF_00200 6.6e-230 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFLKEHFF_00201 6.4e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OFLKEHFF_00202 4.2e-83 ybbJ J acetyltransferase
OFLKEHFF_00203 3.6e-76 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
OFLKEHFF_00207 1.5e-07
OFLKEHFF_00209 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OFLKEHFF_00210 5.2e-113 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OFLKEHFF_00211 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OFLKEHFF_00212 3.9e-217 ybbR S protein conserved in bacteria
OFLKEHFF_00213 2.3e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OFLKEHFF_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OFLKEHFF_00215 2.2e-146 V ATPases associated with a variety of cellular activities
OFLKEHFF_00216 5.4e-97 S ABC-2 family transporter protein
OFLKEHFF_00217 3.4e-275 KLT Protein kinase domain
OFLKEHFF_00219 1.4e-92 H Tellurite resistance protein TehB
OFLKEHFF_00220 9.3e-158 dkgB S Aldo/keto reductase family
OFLKEHFF_00221 1.5e-92 yxaC M effector of murein hydrolase
OFLKEHFF_00222 1.7e-50 S LrgA family
OFLKEHFF_00223 7.7e-68 yxaD K helix_turn_helix multiple antibiotic resistance protein
OFLKEHFF_00224 2.4e-256 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
OFLKEHFF_00225 1.3e-93 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OFLKEHFF_00226 1.8e-103 T Histidine kinase
OFLKEHFF_00227 1.2e-83 KT helix_turn_helix, Lux Regulon
OFLKEHFF_00228 2.4e-135 V ABC transporter, ATP-binding protein
OFLKEHFF_00229 4.4e-145 V ABC-2 type transporter
OFLKEHFF_00230 4.6e-123 V ABC-2 type transporter
OFLKEHFF_00231 4.4e-14
OFLKEHFF_00232 6.2e-59 bacT Q Thioesterase domain
OFLKEHFF_00233 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
OFLKEHFF_00234 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
OFLKEHFF_00235 1.8e-120 fabD 2.3.1.39 I PFAM Acyl transferase
OFLKEHFF_00236 0.0 Q Beta-ketoacyl synthase
OFLKEHFF_00237 0.0 Q Polyketide synthase modules and related proteins
OFLKEHFF_00238 8.4e-98 Q Flavin containing amine oxidoreductase
OFLKEHFF_00239 0.0 Q TIGRFAM amino acid adenylation domain
OFLKEHFF_00240 2.7e-50 crtF 2.1.1.210 Q PFAM O-methyltransferase
OFLKEHFF_00241 1.2e-74 S Domain of unknown function (DUF4879)
OFLKEHFF_00242 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
OFLKEHFF_00243 8.1e-99 yqeB
OFLKEHFF_00244 2.3e-38 ybyB
OFLKEHFF_00245 8.9e-290 ybeC E amino acid
OFLKEHFF_00246 3.4e-15 S Protein of unknown function (DUF2651)
OFLKEHFF_00247 2.2e-162 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OFLKEHFF_00248 4.3e-258 glpT G -transporter
OFLKEHFF_00249 9.2e-18 S Protein of unknown function (DUF2651)
OFLKEHFF_00250 9.5e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
OFLKEHFF_00252 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
OFLKEHFF_00253 3.3e-17
OFLKEHFF_00254 1e-81 K Helix-turn-helix XRE-family like proteins
OFLKEHFF_00255 2.9e-188 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OFLKEHFF_00256 3.2e-209 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OFLKEHFF_00257 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OFLKEHFF_00258 5.1e-84 ybfM S SNARE associated Golgi protein
OFLKEHFF_00259 2e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
OFLKEHFF_00260 2.8e-39 ybfN
OFLKEHFF_00261 8.3e-187 yceA S Belongs to the UPF0176 family
OFLKEHFF_00262 3.7e-211 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFLKEHFF_00263 6.3e-196 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OFLKEHFF_00264 1.4e-249 mmuP E amino acid
OFLKEHFF_00265 1e-176 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
OFLKEHFF_00266 3.2e-251 agcS E Sodium alanine symporter
OFLKEHFF_00267 3.4e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
OFLKEHFF_00268 4.4e-199 phoQ 2.7.13.3 T Histidine kinase
OFLKEHFF_00269 4.8e-155 glnL T Regulator
OFLKEHFF_00270 3.9e-125 ycbJ S Macrolide 2'-phosphotransferase
OFLKEHFF_00271 4.5e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
OFLKEHFF_00272 8.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OFLKEHFF_00273 8.1e-111 ydfN C nitroreductase
OFLKEHFF_00274 1.7e-181 ydfO E COG0346 Lactoylglutathione lyase and related lyases
OFLKEHFF_00275 6.3e-61 mhqP S DoxX
OFLKEHFF_00276 2.8e-57 traF CO Thioredoxin
OFLKEHFF_00277 7.4e-62 ycbP S Protein of unknown function (DUF2512)
OFLKEHFF_00278 1.1e-77 sleB 3.5.1.28 M Cell wall
OFLKEHFF_00279 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
OFLKEHFF_00280 2.4e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OFLKEHFF_00281 1.3e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OFLKEHFF_00282 6.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OFLKEHFF_00283 1.8e-193 ycbU E Selenocysteine lyase
OFLKEHFF_00284 7.6e-237 lmrB EGP the major facilitator superfamily
OFLKEHFF_00285 6.1e-97 yxaF K Transcriptional regulator
OFLKEHFF_00286 6.1e-109 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OFLKEHFF_00287 1.1e-187 yccF K DNA-templated transcriptional preinitiation complex assembly
OFLKEHFF_00288 3.3e-164 yccK C Aldo keto reductase
OFLKEHFF_00289 2.7e-164 ycdA S Domain of unknown function (DUF5105)
OFLKEHFF_00290 8.8e-230 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
OFLKEHFF_00291 2.4e-248 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
OFLKEHFF_00292 2.3e-87 cwlK M D-alanyl-D-alanine carboxypeptidase
OFLKEHFF_00293 2.4e-185 S response regulator aspartate phosphatase
OFLKEHFF_00294 3.7e-137 IQ Enoyl-(Acyl carrier protein) reductase
OFLKEHFF_00295 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
OFLKEHFF_00296 2.7e-161 adcA P Belongs to the bacterial solute-binding protein 9 family
OFLKEHFF_00297 1.6e-131 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OFLKEHFF_00298 2.2e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OFLKEHFF_00299 6.4e-182 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFLKEHFF_00300 2.8e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
OFLKEHFF_00301 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
OFLKEHFF_00302 3.3e-106 yceE T proteins involved in stress response, homologs of TerZ and
OFLKEHFF_00303 2.2e-137 terC P Protein of unknown function (DUF475)
OFLKEHFF_00304 7.9e-307 yceG S Putative component of 'biosynthetic module'
OFLKEHFF_00305 5.7e-192 yceH P Belongs to the TelA family
OFLKEHFF_00306 6.7e-210 naiP P Uncharacterised MFS-type transporter YbfB
OFLKEHFF_00308 4.8e-227 proV 3.6.3.32 E glycine betaine
OFLKEHFF_00309 1.8e-137 opuAB P glycine betaine
OFLKEHFF_00310 1.2e-160 opuAC E glycine betaine
OFLKEHFF_00311 3.2e-206 amhX S amidohydrolase
OFLKEHFF_00312 5.5e-227 ycgA S Membrane
OFLKEHFF_00313 5.2e-42 ycgB
OFLKEHFF_00314 3.2e-11 S RDD family
OFLKEHFF_00315 6.2e-12 S RDD family
OFLKEHFF_00316 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OFLKEHFF_00317 2.2e-258 mdr EGP Major facilitator Superfamily
OFLKEHFF_00318 2.9e-73 emrR K helix_turn_helix multiple antibiotic resistance protein
OFLKEHFF_00319 6.1e-114 ycgF E Lysine exporter protein LysE YggA
OFLKEHFF_00320 1.5e-146 yqcI S YqcI/YcgG family
OFLKEHFF_00321 1.6e-241 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
OFLKEHFF_00322 4.2e-112 ycgI S Domain of unknown function (DUF1989)
OFLKEHFF_00323 6.4e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OFLKEHFF_00324 1.7e-129 4.2.1.118 G Xylose isomerase-like TIM barrel
OFLKEHFF_00325 1.6e-220 G COG0477 Permeases of the major facilitator superfamily
OFLKEHFF_00326 9.6e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OFLKEHFF_00327 1.2e-180 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
OFLKEHFF_00328 7.6e-138 ycgL S Predicted nucleotidyltransferase
OFLKEHFF_00329 1.6e-168 ycgM E Proline dehydrogenase
OFLKEHFF_00330 7.6e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OFLKEHFF_00331 1.6e-242 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OFLKEHFF_00332 1.7e-224 ycgP QT COG2508 Regulator of polyketide synthase expression
OFLKEHFF_00333 1.5e-183 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OFLKEHFF_00334 1.1e-259 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OFLKEHFF_00335 8.6e-56 nirD 1.7.1.15 P Nitrite reductase
OFLKEHFF_00336 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OFLKEHFF_00337 1.8e-223 yciC S GTPases (G3E family)
OFLKEHFF_00338 5.8e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OFLKEHFF_00339 5.2e-72 yckC S membrane
OFLKEHFF_00340 1e-48 S Protein of unknown function (DUF2680)
OFLKEHFF_00341 7.5e-285 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFLKEHFF_00342 1.6e-64 nin S Competence protein J (ComJ)
OFLKEHFF_00343 9.3e-77 nucA M Deoxyribonuclease NucA/NucB
OFLKEHFF_00344 6.4e-91 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
OFLKEHFF_00345 3.4e-104 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
OFLKEHFF_00346 1.1e-62 hxlR K transcriptional
OFLKEHFF_00347 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFLKEHFF_00348 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFLKEHFF_00349 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
OFLKEHFF_00350 1e-136 srfAD Q thioesterase
OFLKEHFF_00351 1.3e-246 bamJ E Aminotransferase class I and II
OFLKEHFF_00352 8.5e-122 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
OFLKEHFF_00353 1e-105 yczE S membrane
OFLKEHFF_00354 3.4e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OFLKEHFF_00355 1e-117 tcyB P COG0765 ABC-type amino acid transport system, permease component
OFLKEHFF_00356 8.8e-142 tcyA ET Belongs to the bacterial solute-binding protein 3 family
OFLKEHFF_00357 3.8e-154 bsdA K LysR substrate binding domain
OFLKEHFF_00358 4.6e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
OFLKEHFF_00359 3.8e-281 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
OFLKEHFF_00360 9.2e-36 bsdD 4.1.1.61 S response to toxic substance
OFLKEHFF_00361 3.3e-72 yclD
OFLKEHFF_00362 6.8e-265 dtpT E amino acid peptide transporter
OFLKEHFF_00363 7.5e-263 yclG M Pectate lyase superfamily protein
OFLKEHFF_00365 1.3e-272 gerKA EG Spore germination protein
OFLKEHFF_00366 1.4e-226 gerKC S spore germination
OFLKEHFF_00367 1.4e-190 gerKB F Spore germination protein
OFLKEHFF_00368 7.5e-247 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFLKEHFF_00369 2.2e-90 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFLKEHFF_00370 4.8e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
OFLKEHFF_00371 1.3e-114 yxeN P COG0765 ABC-type amino acid transport system, permease component
OFLKEHFF_00372 1.5e-130 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
OFLKEHFF_00373 1e-215 yxeP 3.5.1.47 E hydrolase activity
OFLKEHFF_00374 5.3e-240 yxeQ S MmgE/PrpD family
OFLKEHFF_00375 1.2e-118 yclH P ABC transporter
OFLKEHFF_00376 4.3e-224 yclI V ABC transporter (permease) YclI
OFLKEHFF_00377 9.9e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFLKEHFF_00378 2.8e-255 T PhoQ Sensor
OFLKEHFF_00379 2.3e-74 S aspartate phosphatase
OFLKEHFF_00382 1.2e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
OFLKEHFF_00383 6.3e-163 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFLKEHFF_00384 3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFLKEHFF_00385 4.9e-134 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
OFLKEHFF_00386 1e-173 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
OFLKEHFF_00387 8.1e-247 ycnB EGP Major facilitator Superfamily
OFLKEHFF_00388 3.1e-148 ycnC K Transcriptional regulator
OFLKEHFF_00389 7.5e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
OFLKEHFF_00390 1.4e-44 ycnE S Monooxygenase
OFLKEHFF_00391 1.8e-50 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
OFLKEHFF_00392 4.7e-255 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFLKEHFF_00393 2.9e-211 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OFLKEHFF_00394 1.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OFLKEHFF_00395 2.6e-147 glcU U Glucose uptake
OFLKEHFF_00396 4.3e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFLKEHFF_00397 6.2e-95 ycnI S protein conserved in bacteria
OFLKEHFF_00398 2.4e-287 ycnJ P protein, homolog of Cu resistance protein CopC
OFLKEHFF_00399 4e-104 ycnK K COG1349 Transcriptional regulators of sugar metabolism
OFLKEHFF_00400 2.5e-53
OFLKEHFF_00401 1.8e-222 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
OFLKEHFF_00402 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
OFLKEHFF_00403 2.4e-201 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
OFLKEHFF_00404 7.1e-60 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
OFLKEHFF_00406 2.6e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OFLKEHFF_00407 4.2e-133 ycsF S Belongs to the UPF0271 (lamB) family
OFLKEHFF_00408 1.4e-207 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
OFLKEHFF_00409 1e-145 ycsI S Belongs to the D-glutamate cyclase family
OFLKEHFF_00410 1.1e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
OFLKEHFF_00411 1.9e-178 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
OFLKEHFF_00412 1.1e-125 kipR K Transcriptional regulator
OFLKEHFF_00413 1.2e-112 ycsK E anatomical structure formation involved in morphogenesis
OFLKEHFF_00415 4.7e-54 yczJ S biosynthesis
OFLKEHFF_00416 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
OFLKEHFF_00417 5.2e-167 ydhF S Oxidoreductase
OFLKEHFF_00418 0.0 mtlR K transcriptional regulator, MtlR
OFLKEHFF_00419 3.3e-283 ydaB IQ acyl-CoA ligase
OFLKEHFF_00420 1.8e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFLKEHFF_00421 1.6e-93 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
OFLKEHFF_00422 7.9e-98 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OFLKEHFF_00423 3.4e-76 ydaG 1.4.3.5 S general stress protein
OFLKEHFF_00424 1.5e-136 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
OFLKEHFF_00425 3.9e-47 ydzA EGP Major facilitator Superfamily
OFLKEHFF_00426 4.3e-74 lrpC K Transcriptional regulator
OFLKEHFF_00427 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OFLKEHFF_00428 5.5e-187 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
OFLKEHFF_00429 2.5e-142 ydaK T Diguanylate cyclase, GGDEF domain
OFLKEHFF_00430 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
OFLKEHFF_00431 4.7e-230 ydaM M Glycosyl transferase family group 2
OFLKEHFF_00432 0.0 ydaN S Bacterial cellulose synthase subunit
OFLKEHFF_00433 0.0 ydaO E amino acid
OFLKEHFF_00434 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OFLKEHFF_00437 4.7e-39
OFLKEHFF_00438 1.5e-223 mntH P H( )-stimulated, divalent metal cation uptake system
OFLKEHFF_00440 1.2e-32 ydaT
OFLKEHFF_00441 2.2e-135 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
OFLKEHFF_00443 8.4e-28 ydbC S Domain of unknown function (DUF4937
OFLKEHFF_00444 6.7e-153 ydbD P Catalase
OFLKEHFF_00445 1.5e-194 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
OFLKEHFF_00446 5e-293 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OFLKEHFF_00447 5.5e-113 dctR T COG4565 Response regulator of citrate malate metabolism
OFLKEHFF_00448 3.2e-223 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFLKEHFF_00449 3.3e-157 ydbI S AI-2E family transporter
OFLKEHFF_00450 1.5e-169 ydbJ V ABC transporter, ATP-binding protein
OFLKEHFF_00451 1.7e-126 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OFLKEHFF_00452 1e-51 ydbL
OFLKEHFF_00453 9.2e-201 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OFLKEHFF_00454 3.5e-12 S Fur-regulated basic protein B
OFLKEHFF_00455 9.2e-10 S Fur-regulated basic protein A
OFLKEHFF_00456 6.9e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OFLKEHFF_00457 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OFLKEHFF_00458 1.3e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OFLKEHFF_00459 3e-251 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OFLKEHFF_00460 3.1e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OFLKEHFF_00461 3.4e-56 ydbS S Bacterial PH domain
OFLKEHFF_00462 4.2e-251 ydbT S Membrane
OFLKEHFF_00463 5.8e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
OFLKEHFF_00464 1e-52 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OFLKEHFF_00465 7.9e-180 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
OFLKEHFF_00466 2.5e-214 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OFLKEHFF_00467 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OFLKEHFF_00468 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
OFLKEHFF_00469 7.9e-138 rsbR T Positive regulator of sigma-B
OFLKEHFF_00470 1.8e-57 rsbS T antagonist
OFLKEHFF_00471 2.1e-67 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OFLKEHFF_00472 1.8e-184 rsbU 3.1.3.3 KT phosphatase
OFLKEHFF_00473 2.7e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
OFLKEHFF_00474 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OFLKEHFF_00475 2e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFLKEHFF_00476 1.7e-105 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
OFLKEHFF_00477 0.0 yhgF K COG2183 Transcriptional accessory protein
OFLKEHFF_00478 1.7e-14
OFLKEHFF_00479 1.6e-80 ydcK S Belongs to the SprT family
OFLKEHFF_00487 3.2e-53
OFLKEHFF_00488 2.5e-08
OFLKEHFF_00489 0.0 M Domain of unknown function DUF11
OFLKEHFF_00490 4.6e-76 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
OFLKEHFF_00491 1.4e-09 S response regulator aspartate phosphatase
OFLKEHFF_00493 1.4e-30 cspL K Cold shock
OFLKEHFF_00494 8.6e-73 carD K Transcription factor
OFLKEHFF_00495 5.2e-91 yrkC G Cupin domain
OFLKEHFF_00496 9.6e-78 K Transcriptional regulator
OFLKEHFF_00497 2.2e-98 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OFLKEHFF_00498 5.1e-30 cspL K Cold shock
OFLKEHFF_00499 4.8e-206 Q imidazolonepropionase
OFLKEHFF_00500 2.1e-57 rmaE K MarR family transcriptional regulator
OFLKEHFF_00501 3.6e-89 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OFLKEHFF_00502 1e-166 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFLKEHFF_00503 5.3e-189 ydeG EGP Major facilitator superfamily
OFLKEHFF_00504 2.2e-171 S Patatin-like phospholipase
OFLKEHFF_00506 7.4e-71 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFLKEHFF_00507 1.3e-152 czcD P COG1230 Co Zn Cd efflux system component
OFLKEHFF_00509 5.5e-162 S SNARE associated Golgi protein
OFLKEHFF_00510 1.1e-158 eaeH M Domain of Unknown Function (DUF1259)
OFLKEHFF_00511 4.2e-84 yyaR K Acetyltransferase (GNAT) domain
OFLKEHFF_00512 1.3e-149 ydeE K AraC family transcriptional regulator
OFLKEHFF_00513 1.4e-131 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
OFLKEHFF_00515 4.1e-187 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
OFLKEHFF_00516 2.5e-159 S Sodium Bile acid symporter family
OFLKEHFF_00517 5.6e-197 adhA 1.1.1.1 C alcohol dehydrogenase
OFLKEHFF_00518 1.6e-62 yraB K helix_turn_helix, mercury resistance
OFLKEHFF_00519 3.2e-218 mleN_2 C antiporter
OFLKEHFF_00520 1.6e-247 K helix_turn_helix gluconate operon transcriptional repressor
OFLKEHFF_00521 2.9e-100 paiB K Transcriptional regulator
OFLKEHFF_00523 5.6e-145 ydeK EG -transporter
OFLKEHFF_00524 9.3e-256 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFLKEHFF_00525 6.8e-47 yraD M Spore coat protein
OFLKEHFF_00526 2.2e-25 yraE
OFLKEHFF_00527 3.7e-218 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OFLKEHFF_00528 9.3e-62 yraF M Spore coat protein
OFLKEHFF_00529 3.2e-34 yraG
OFLKEHFF_00530 3.2e-127 puuD S Peptidase C26
OFLKEHFF_00531 2.8e-280 expZ S ABC transporter
OFLKEHFF_00532 7.5e-89 ynaD J Acetyltransferase (GNAT) domain
OFLKEHFF_00533 7.2e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
OFLKEHFF_00534 6.3e-194 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OFLKEHFF_00535 2e-206 tcaB EGP Major facilitator Superfamily
OFLKEHFF_00536 6.2e-219 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OFLKEHFF_00537 5.2e-153 K Helix-turn-helix XRE-family like proteins
OFLKEHFF_00538 2.5e-122 ydhB S membrane transporter protein
OFLKEHFF_00539 5.1e-78 bltD 2.3.1.57 K FR47-like protein
OFLKEHFF_00540 1e-140 bltR K helix_turn_helix, mercury resistance
OFLKEHFF_00541 1.5e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OFLKEHFF_00542 4.9e-108 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
OFLKEHFF_00543 6.1e-107 S Alpha/beta hydrolase family
OFLKEHFF_00544 3.6e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
OFLKEHFF_00545 1.4e-111 ydhC K FCD
OFLKEHFF_00546 4.1e-220 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OFLKEHFF_00548 8.5e-246 pbpE V Beta-lactamase
OFLKEHFF_00550 8e-97 ydhK M Protein of unknown function (DUF1541)
OFLKEHFF_00551 1.8e-191 pbuE EGP Major facilitator Superfamily
OFLKEHFF_00552 1.1e-113 K FCD
OFLKEHFF_00553 8.8e-210 yeaN P COG2807 Cyanate permease
OFLKEHFF_00554 1.9e-47 sugE P Small Multidrug Resistance protein
OFLKEHFF_00555 6.8e-48 ykkC P Small Multidrug Resistance protein
OFLKEHFF_00556 1.3e-97 yvdT K Transcriptional regulator
OFLKEHFF_00557 1.8e-292 yveA E amino acid
OFLKEHFF_00558 4.8e-162 ydhU P Catalase
OFLKEHFF_00559 3.3e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
OFLKEHFF_00560 4.7e-177 yhfP 1.1.1.1 C Quinone oxidoreductase
OFLKEHFF_00561 4.4e-245 iolT EGP Major facilitator Superfamily
OFLKEHFF_00564 2.2e-38 S COG NOG14552 non supervised orthologous group
OFLKEHFF_00565 7.8e-08
OFLKEHFF_00567 4.5e-172 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OFLKEHFF_00568 2.2e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
OFLKEHFF_00569 5.1e-122 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
OFLKEHFF_00570 9e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OFLKEHFF_00571 6.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OFLKEHFF_00572 1.1e-310 ydiF S ABC transporter
OFLKEHFF_00573 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OFLKEHFF_00574 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OFLKEHFF_00575 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OFLKEHFF_00576 5e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OFLKEHFF_00577 1.7e-27 ydiK S Domain of unknown function (DUF4305)
OFLKEHFF_00578 6.9e-125 ydiL S CAAX protease self-immunity
OFLKEHFF_00579 6.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OFLKEHFF_00580 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OFLKEHFF_00581 7.9e-153 ydjC S Abhydrolase domain containing 18
OFLKEHFF_00582 0.0 K NB-ARC domain
OFLKEHFF_00583 1.3e-196 gutB 1.1.1.14 E Dehydrogenase
OFLKEHFF_00584 3.1e-243 gutA G MFS/sugar transport protein
OFLKEHFF_00585 3e-168 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
OFLKEHFF_00586 2.4e-30 yjdJ S Domain of unknown function (DUF4306)
OFLKEHFF_00587 1e-109 pspA KT Phage shock protein A
OFLKEHFF_00588 9.5e-173 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OFLKEHFF_00589 2.8e-113 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
OFLKEHFF_00590 9e-144 ydjI S virion core protein (lumpy skin disease virus)
OFLKEHFF_00591 0.0 yrhL I Acyltransferase family
OFLKEHFF_00592 5.2e-140 rsiV S Protein of unknown function (DUF3298)
OFLKEHFF_00593 3.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OFLKEHFF_00594 6.4e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OFLKEHFF_00595 4.2e-62 ydjM M Lytic transglycolase
OFLKEHFF_00596 1.2e-130 ydjN U Involved in the tonB-independent uptake of proteins
OFLKEHFF_00598 7.1e-34 ydjO S Cold-inducible protein YdjO
OFLKEHFF_00599 4.3e-302 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OFLKEHFF_00600 1.9e-237 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
OFLKEHFF_00601 9.4e-12 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OFLKEHFF_00602 4.9e-92 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
OFLKEHFF_00603 4.3e-50 S ATP-grasp domain
OFLKEHFF_00604 7.7e-60 setB G Major Facilitator Superfamily
OFLKEHFF_00605 9.1e-69 purD 6.3.4.13 F ATP-grasp domain
OFLKEHFF_00606 1e-65 C Taurine catabolism dioxygenase TauD, TfdA family
OFLKEHFF_00607 1.8e-45 racX 5.1.1.13 M Asp/Glu/Hydantoin racemase
OFLKEHFF_00608 2.2e-21 dppA E Family 5
OFLKEHFF_00609 2.9e-37 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OFLKEHFF_00610 8.6e-176 yeaC S COG0714 MoxR-like ATPases
OFLKEHFF_00611 2.1e-200 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
OFLKEHFF_00612 0.0 yebA E COG1305 Transglutaminase-like enzymes
OFLKEHFF_00613 2.8e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OFLKEHFF_00614 5.2e-90 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OFLKEHFF_00615 4.1e-246 S Domain of unknown function (DUF4179)
OFLKEHFF_00616 8.1e-209 pbuG S permease
OFLKEHFF_00617 1.1e-123 yebC M Membrane
OFLKEHFF_00619 8.9e-93 yebE S UPF0316 protein
OFLKEHFF_00620 9.5e-29 yebG S NETI protein
OFLKEHFF_00621 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OFLKEHFF_00622 1.7e-218 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OFLKEHFF_00623 8.9e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OFLKEHFF_00624 6.1e-126 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OFLKEHFF_00625 4.2e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OFLKEHFF_00626 6.8e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OFLKEHFF_00627 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OFLKEHFF_00628 4.9e-268 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OFLKEHFF_00629 8.7e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OFLKEHFF_00630 2.2e-102 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OFLKEHFF_00631 7.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OFLKEHFF_00632 7.2e-231 purD 6.3.4.13 F Belongs to the GARS family
OFLKEHFF_00633 3.8e-62 K helix_turn_helix ASNC type
OFLKEHFF_00634 2.8e-134 yjeH E Amino acid permease
OFLKEHFF_00635 3.3e-25 S Protein of unknown function (DUF2892)
OFLKEHFF_00636 0.0 yerA 3.5.4.2 F adenine deaminase
OFLKEHFF_00637 5e-187 yerB S Protein of unknown function (DUF3048) C-terminal domain
OFLKEHFF_00638 3.1e-50 yerC S protein conserved in bacteria
OFLKEHFF_00639 2.6e-299 yerD 1.4.7.1 E Belongs to the glutamate synthase family
OFLKEHFF_00640 9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OFLKEHFF_00641 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OFLKEHFF_00642 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OFLKEHFF_00643 5.2e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
OFLKEHFF_00644 2.3e-184 yerI S homoserine kinase type II (protein kinase fold)
OFLKEHFF_00645 6.9e-119 sapB S MgtC SapB transporter
OFLKEHFF_00646 8.3e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OFLKEHFF_00647 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OFLKEHFF_00648 1.5e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OFLKEHFF_00649 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OFLKEHFF_00650 1.1e-147 yerO K Transcriptional regulator
OFLKEHFF_00651 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OFLKEHFF_00652 3.3e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OFLKEHFF_00653 1.1e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OFLKEHFF_00654 6.1e-35
OFLKEHFF_00655 3.3e-53 S Protein of unknown function, DUF600
OFLKEHFF_00656 2.5e-51 S Protein of unknown function, DUF600
OFLKEHFF_00657 3.7e-54 yobL L nucleic acid phosphodiester bond hydrolysis
OFLKEHFF_00658 4.4e-41 S Immunity protein 22
OFLKEHFF_00659 3.4e-32 yobL S Bacterial EndoU nuclease
OFLKEHFF_00660 1.3e-21 yobL L nucleic acid phosphodiester bond hydrolysis
OFLKEHFF_00661 1.3e-18
OFLKEHFF_00662 9.3e-251 yobL S Bacterial EndoU nuclease
OFLKEHFF_00663 1.2e-126 yeeN K transcriptional regulatory protein
OFLKEHFF_00665 4.3e-110 aadK G Streptomycin adenylyltransferase
OFLKEHFF_00666 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
OFLKEHFF_00667 1.3e-44 cotJB S CotJB protein
OFLKEHFF_00668 2e-103 cotJC P Spore Coat
OFLKEHFF_00669 4.9e-88 yesJ K Acetyltransferase (GNAT) family
OFLKEHFF_00671 1e-114 yetF S membrane
OFLKEHFF_00672 4.1e-53 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
OFLKEHFF_00673 1.2e-61 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFLKEHFF_00674 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OFLKEHFF_00675 2.9e-21 yezD S Uncharacterized small protein (DUF2292)
OFLKEHFF_00676 1.2e-54 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
OFLKEHFF_00677 2e-104 yetJ S Belongs to the BI1 family
OFLKEHFF_00679 9.2e-84 yetL K helix_turn_helix multiple antibiotic resistance protein
OFLKEHFF_00680 9e-193 yetM CH FAD binding domain
OFLKEHFF_00681 7.5e-197 yetN S Protein of unknown function (DUF3900)
OFLKEHFF_00682 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OFLKEHFF_00683 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OFLKEHFF_00684 2.5e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
OFLKEHFF_00685 2.4e-172 yfnG 4.2.1.45 M dehydratase
OFLKEHFF_00686 2.6e-174 yfnF M Nucleotide-diphospho-sugar transferase
OFLKEHFF_00687 6.9e-212 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
OFLKEHFF_00688 5.3e-178 yfnD M Nucleotide-diphospho-sugar transferase
OFLKEHFF_00689 3e-213 fsr P COG0477 Permeases of the major facilitator superfamily
OFLKEHFF_00690 7.6e-242 yfnA E amino acid
OFLKEHFF_00691 2.5e-275 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OFLKEHFF_00692 1.1e-105 yfmS NT chemotaxis protein
OFLKEHFF_00693 1.4e-164 IQ Enoyl-(Acyl carrier protein) reductase
OFLKEHFF_00694 3.9e-201 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OFLKEHFF_00695 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OFLKEHFF_00697 5.8e-68 yfmP K transcriptional
OFLKEHFF_00698 3.2e-196 yfmO EGP Major facilitator Superfamily
OFLKEHFF_00699 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OFLKEHFF_00700 7.4e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
OFLKEHFF_00701 2e-183 yfmJ S N-terminal domain of oxidoreductase
OFLKEHFF_00702 7e-25 S Protein of unknown function (DUF3212)
OFLKEHFF_00703 1.3e-57 yflT S Heat induced stress protein YflT
OFLKEHFF_00704 3.8e-232 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
OFLKEHFF_00705 1e-233 yflS P Sodium:sulfate symporter transmembrane region
OFLKEHFF_00706 0.0 ywpD T PhoQ Sensor
OFLKEHFF_00707 2.2e-151 M1-574 T Transcriptional regulatory protein, C terminal
OFLKEHFF_00708 0.0 M1-568 M cell wall anchor domain
OFLKEHFF_00709 8.7e-79 srtA 3.4.22.70 M Sortase family
OFLKEHFF_00710 1.1e-263 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OFLKEHFF_00711 6e-115 citT T response regulator
OFLKEHFF_00712 2.4e-170 yflP S Tripartite tricarboxylate transporter family receptor
OFLKEHFF_00714 3.7e-222 citM C Citrate transporter
OFLKEHFF_00715 2.3e-142 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
OFLKEHFF_00716 7.6e-213 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OFLKEHFF_00717 6.7e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OFLKEHFF_00718 3.9e-119 yflK S protein conserved in bacteria
OFLKEHFF_00719 1.5e-14 yflJ S Protein of unknown function (DUF2639)
OFLKEHFF_00720 4.5e-18 yflI
OFLKEHFF_00721 3.1e-50 yflH S Protein of unknown function (DUF3243)
OFLKEHFF_00722 2.6e-135 map 3.4.11.18 E Methionine aminopeptidase
OFLKEHFF_00723 2.4e-240 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
OFLKEHFF_00724 8.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
OFLKEHFF_00725 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OFLKEHFF_00726 9.5e-62 yhdN S Domain of unknown function (DUF1992)
OFLKEHFF_00727 1.8e-77 cotP O Belongs to the small heat shock protein (HSP20) family
OFLKEHFF_00728 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
OFLKEHFF_00729 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
OFLKEHFF_00730 2.3e-238 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFLKEHFF_00731 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OFLKEHFF_00732 2.1e-126 treR K transcriptional
OFLKEHFF_00733 5.5e-121 yfkO C nitroreductase
OFLKEHFF_00734 3.8e-118 yibF S YibE/F-like protein
OFLKEHFF_00735 2.8e-186 yibE S YibE/F-like protein
OFLKEHFF_00736 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
OFLKEHFF_00737 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
OFLKEHFF_00738 4.9e-177 K helix_turn _helix lactose operon repressor
OFLKEHFF_00739 3e-159 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OFLKEHFF_00740 3.8e-126 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OFLKEHFF_00741 1.2e-35 ydiM EGP Major facilitator Superfamily
OFLKEHFF_00742 3.9e-28 yfkK S Belongs to the UPF0435 family
OFLKEHFF_00743 9.4e-83 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OFLKEHFF_00744 4.4e-47 yfkI S gas vesicle protein
OFLKEHFF_00745 1.2e-141 yihY S Belongs to the UPF0761 family
OFLKEHFF_00746 1.1e-214 ycaD EGP COG0477 Permeases of the major facilitator superfamily
OFLKEHFF_00747 3e-182 cax P COG0387 Ca2 H antiporter
OFLKEHFF_00748 1.6e-140 yfkD S YfkD-like protein
OFLKEHFF_00749 1.3e-143 yfkC M Mechanosensitive ion channel
OFLKEHFF_00750 1.1e-217 yfkA S YfkB-like domain
OFLKEHFF_00751 4.9e-27 yfjT
OFLKEHFF_00752 4.9e-153 pdaA G deacetylase
OFLKEHFF_00753 9.5e-142 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
OFLKEHFF_00754 3.1e-28
OFLKEHFF_00755 2.5e-183 corA P Mediates influx of magnesium ions
OFLKEHFF_00756 1.9e-158 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OFLKEHFF_00757 3.8e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OFLKEHFF_00758 1.8e-44 S YfzA-like protein
OFLKEHFF_00759 1.5e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OFLKEHFF_00760 1.6e-76 yfjM S Psort location Cytoplasmic, score
OFLKEHFF_00761 2.8e-185 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OFLKEHFF_00762 2e-186 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OFLKEHFF_00763 6.6e-202 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OFLKEHFF_00764 2.4e-240 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OFLKEHFF_00765 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OFLKEHFF_00766 3.2e-15 sspH S Belongs to the SspH family
OFLKEHFF_00767 1.2e-260 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OFLKEHFF_00768 7.3e-138 glvR F Helix-turn-helix domain, rpiR family
OFLKEHFF_00769 2.8e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFLKEHFF_00770 0.0 yobO M COG5434 Endopolygalacturonase
OFLKEHFF_00771 2.4e-301 yfiB3 V ABC transporter
OFLKEHFF_00772 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
OFLKEHFF_00773 1.6e-62 mhqP S DoxX
OFLKEHFF_00774 4.8e-154 yfiE 1.13.11.2 S glyoxalase
OFLKEHFF_00775 4.4e-164 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OFLKEHFF_00776 5.8e-92 padR K transcriptional
OFLKEHFF_00777 3.4e-98 1.6.5.2 S NADPH-dependent FMN reductase
OFLKEHFF_00778 8.5e-172 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OFLKEHFF_00779 2.2e-44 yrdF K ribonuclease inhibitor
OFLKEHFF_00780 1e-93 yfiT S Belongs to the metal hydrolase YfiT family
OFLKEHFF_00781 7.8e-283 yfiU EGP Major facilitator Superfamily
OFLKEHFF_00782 1.6e-77 yfiV K transcriptional
OFLKEHFF_00783 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OFLKEHFF_00784 7.2e-153 yfhB 5.3.3.17 S PhzF family
OFLKEHFF_00785 4.1e-104 yfhC C nitroreductase
OFLKEHFF_00786 1e-24 yfhD S YfhD-like protein
OFLKEHFF_00788 1.2e-163 yfhF S nucleoside-diphosphate sugar epimerase
OFLKEHFF_00789 9e-139 recX 2.4.1.337 GT4 S Modulates RecA activity
OFLKEHFF_00790 2.7e-46 yfhH S Protein of unknown function (DUF1811)
OFLKEHFF_00791 4.2e-204 yfhI EGP Major facilitator Superfamily
OFLKEHFF_00793 1.8e-159 mpr 3.4.21.19 M Belongs to the peptidase S1B family
OFLKEHFF_00794 8.3e-44 yfhJ S WVELL protein
OFLKEHFF_00795 1.1e-87 batE T Bacterial SH3 domain homologues
OFLKEHFF_00796 3.8e-30 yfhL S SdpI/YhfL protein family
OFLKEHFF_00797 1.1e-166 yfhM S Alpha/beta hydrolase family
OFLKEHFF_00798 2.3e-184 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OFLKEHFF_00799 0.0 yfhO S Bacterial membrane protein YfhO
OFLKEHFF_00800 4.5e-180 yfhP S membrane-bound metal-dependent
OFLKEHFF_00801 1.9e-203 mutY L A G-specific
OFLKEHFF_00802 1.8e-36 yfhS
OFLKEHFF_00803 2e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFLKEHFF_00805 9.7e-37 ygaB S YgaB-like protein
OFLKEHFF_00806 2.2e-104 ygaC J Belongs to the UPF0374 family
OFLKEHFF_00807 3.1e-301 ygaD V ABC transporter
OFLKEHFF_00808 1.7e-177 ygaE S Membrane
OFLKEHFF_00809 4.9e-243 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OFLKEHFF_00810 7.2e-83 bcp 1.11.1.15 O Peroxiredoxin
OFLKEHFF_00811 3.1e-80 perR P Belongs to the Fur family
OFLKEHFF_00812 5.6e-56 ygzB S UPF0295 protein
OFLKEHFF_00813 4.2e-161 ygxA S Nucleotidyltransferase-like
OFLKEHFF_00814 2.2e-38 S COG NOG14552 non supervised orthologous group
OFLKEHFF_00819 7.8e-08
OFLKEHFF_00827 2e-08
OFLKEHFF_00831 9.2e-276 C Na+/H+ antiporter family
OFLKEHFF_00832 3.6e-123 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
OFLKEHFF_00833 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OFLKEHFF_00834 1.1e-242 ygaK C Berberine and berberine like
OFLKEHFF_00836 7e-229 oppA5 E PFAM extracellular solute-binding protein family 5
OFLKEHFF_00837 1e-144 appB P Binding-protein-dependent transport system inner membrane component
OFLKEHFF_00838 1.2e-126 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFLKEHFF_00839 3.4e-135 oppD3 P Belongs to the ABC transporter superfamily
OFLKEHFF_00840 1.3e-131 oppF3 E Belongs to the ABC transporter superfamily
OFLKEHFF_00841 1.8e-286 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OFLKEHFF_00842 2.3e-178 S Amidohydrolase
OFLKEHFF_00843 1.6e-137 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
OFLKEHFF_00844 2.9e-171 ssuA M Sulfonate ABC transporter
OFLKEHFF_00845 2.4e-142 ssuC P ABC transporter (permease)
OFLKEHFF_00846 7.9e-213 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
OFLKEHFF_00847 1.1e-40 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OFLKEHFF_00848 7.6e-77 ygaO
OFLKEHFF_00849 6.2e-23 K Transcriptional regulator
OFLKEHFF_00851 5.1e-105 yhzB S B3/4 domain
OFLKEHFF_00852 7.3e-222 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OFLKEHFF_00853 7.7e-169 yhbB S Putative amidase domain
OFLKEHFF_00854 4.5e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OFLKEHFF_00855 2.9e-103 yhbD K Protein of unknown function (DUF4004)
OFLKEHFF_00856 1.8e-53 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
OFLKEHFF_00857 5.9e-57 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
OFLKEHFF_00859 0.0 prkA T Ser protein kinase
OFLKEHFF_00860 8.2e-213 yhbH S Belongs to the UPF0229 family
OFLKEHFF_00861 8.1e-71 yhbI K DNA-binding transcription factor activity
OFLKEHFF_00862 4.4e-96 yhbJ V COG1566 Multidrug resistance efflux pump
OFLKEHFF_00863 4.1e-284 yhcA EGP Major facilitator Superfamily
OFLKEHFF_00864 1e-98 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
OFLKEHFF_00865 8.2e-50 yhcC
OFLKEHFF_00866 4.3e-53
OFLKEHFF_00867 1.3e-58 yhcF K Transcriptional regulator
OFLKEHFF_00868 1.8e-114 yhcG V ABC transporter, ATP-binding protein
OFLKEHFF_00869 7.2e-164 yhcH V ABC transporter, ATP-binding protein
OFLKEHFF_00870 7.9e-158 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OFLKEHFF_00871 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
OFLKEHFF_00872 1.1e-129 metQ M Belongs to the nlpA lipoprotein family
OFLKEHFF_00873 5.3e-180 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
OFLKEHFF_00874 1.4e-227 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFLKEHFF_00875 1.4e-38 yhcM
OFLKEHFF_00876 2.2e-80 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OFLKEHFF_00877 7.3e-153 yhcP
OFLKEHFF_00878 3.9e-111 yhcQ M Spore coat protein
OFLKEHFF_00879 6.8e-295 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
OFLKEHFF_00880 3.3e-101 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
OFLKEHFF_00881 7.4e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OFLKEHFF_00882 2.8e-64 yhcU S Family of unknown function (DUF5365)
OFLKEHFF_00883 7.6e-68 yhcV S COG0517 FOG CBS domain
OFLKEHFF_00884 1.6e-123 yhcW 5.4.2.6 S hydrolase
OFLKEHFF_00885 1.9e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OFLKEHFF_00886 8.4e-254 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OFLKEHFF_00887 3.2e-101 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OFLKEHFF_00888 4.7e-138 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
OFLKEHFF_00889 4e-289 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OFLKEHFF_00890 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OFLKEHFF_00891 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OFLKEHFF_00892 1.6e-192 yhcY 2.7.13.3 T Histidine kinase
OFLKEHFF_00893 8.2e-106 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFLKEHFF_00894 7.9e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
OFLKEHFF_00895 3e-37 yhdB S YhdB-like protein
OFLKEHFF_00896 3.8e-51 yhdC S Protein of unknown function (DUF3889)
OFLKEHFF_00897 1.4e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OFLKEHFF_00898 2.6e-71 nsrR K Transcriptional regulator
OFLKEHFF_00899 2e-248 ygxB M Conserved TM helix
OFLKEHFF_00900 5.1e-262 ycgB S Stage V sporulation protein R
OFLKEHFF_00901 1.4e-251 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OFLKEHFF_00902 1.6e-122 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OFLKEHFF_00903 3.1e-156 citR K Transcriptional regulator
OFLKEHFF_00904 1.3e-196 citA 2.3.3.1 C Belongs to the citrate synthase family
OFLKEHFF_00905 1.2e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFLKEHFF_00906 6.1e-247 yhdG E amino acid
OFLKEHFF_00907 5.9e-196 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OFLKEHFF_00908 8.1e-45 yhdK S Sigma-M inhibitor protein
OFLKEHFF_00909 3.2e-195 yhdL S Sigma factor regulator N-terminal
OFLKEHFF_00910 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
OFLKEHFF_00911 2.6e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OFLKEHFF_00912 4e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OFLKEHFF_00913 1.8e-69 cueR K transcriptional
OFLKEHFF_00914 6.5e-218 yhdR 2.6.1.1 E Aminotransferase
OFLKEHFF_00915 1.4e-226 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OFLKEHFF_00916 3.3e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
OFLKEHFF_00917 3.9e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OFLKEHFF_00918 2.8e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OFLKEHFF_00919 1.1e-122 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OFLKEHFF_00921 6e-197 yhdY M Mechanosensitive ion channel
OFLKEHFF_00922 8.8e-136 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OFLKEHFF_00923 1.1e-150 yheN G deacetylase
OFLKEHFF_00924 3e-148 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OFLKEHFF_00925 1.1e-81 pksA K Transcriptional regulator
OFLKEHFF_00926 3e-88 ymcC S Membrane
OFLKEHFF_00927 6.8e-84 T universal stress protein
OFLKEHFF_00928 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
OFLKEHFF_00929 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
OFLKEHFF_00930 2.1e-98 yheG GM NAD(P)H-binding
OFLKEHFF_00932 3.8e-28 sspB S spore protein
OFLKEHFF_00933 1.7e-36 yheE S Family of unknown function (DUF5342)
OFLKEHFF_00934 1.7e-249 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OFLKEHFF_00935 1.1e-200 yheC HJ YheC/D like ATP-grasp
OFLKEHFF_00936 1.1e-201 yheB S Belongs to the UPF0754 family
OFLKEHFF_00937 2.8e-52 yheA S Belongs to the UPF0342 family
OFLKEHFF_00938 2.7e-152 yhaX S haloacid dehalogenase-like hydrolase
OFLKEHFF_00939 5.6e-291 hemZ H coproporphyrinogen III oxidase
OFLKEHFF_00940 6.8e-245 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
OFLKEHFF_00941 2.1e-203 yhaU P COG0475 Kef-type K transport systems, membrane components
OFLKEHFF_00942 8.6e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
OFLKEHFF_00944 1e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
OFLKEHFF_00945 1.2e-14 S YhzD-like protein
OFLKEHFF_00946 3.9e-162 yhaQ S ABC transporter, ATP-binding protein
OFLKEHFF_00947 2.7e-201 yhaP CP COG1668 ABC-type Na efflux pump, permease component
OFLKEHFF_00948 1.2e-230 yhaO L DNA repair exonuclease
OFLKEHFF_00949 0.0 yhaN L AAA domain
OFLKEHFF_00950 1.1e-175 yhaM L Shows a 3'-5' exoribonuclease activity
OFLKEHFF_00951 8.9e-31 yhaL S Sporulation protein YhaL
OFLKEHFF_00952 2.2e-114 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OFLKEHFF_00953 1.6e-94 yhaK S Putative zincin peptidase
OFLKEHFF_00954 9.9e-55 yhaI S Protein of unknown function (DUF1878)
OFLKEHFF_00955 1.4e-110 hpr K Negative regulator of protease production and sporulation
OFLKEHFF_00956 9e-38 yhaH S YtxH-like protein
OFLKEHFF_00957 2e-17
OFLKEHFF_00958 7.9e-75 trpP S Tryptophan transporter TrpP
OFLKEHFF_00959 5.2e-198 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OFLKEHFF_00960 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OFLKEHFF_00961 1.1e-135 ecsA V transporter (ATP-binding protein)
OFLKEHFF_00962 7.5e-217 ecsB U ABC transporter
OFLKEHFF_00963 1.3e-117 ecsC S EcsC protein family
OFLKEHFF_00964 2.1e-216 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OFLKEHFF_00965 2.1e-236 yhfA C membrane
OFLKEHFF_00966 7.8e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
OFLKEHFF_00967 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OFLKEHFF_00968 1.9e-198 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OFLKEHFF_00969 5.8e-177 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OFLKEHFF_00970 9.5e-272 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OFLKEHFF_00971 3e-99 yhgD K Transcriptional regulator
OFLKEHFF_00972 2.9e-254 yhgE S YhgE Pip N-terminal domain protein
OFLKEHFF_00973 1.5e-175 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OFLKEHFF_00975 1.1e-195 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
OFLKEHFF_00976 3.2e-226 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OFLKEHFF_00977 2.8e-134 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
OFLKEHFF_00978 1.7e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
OFLKEHFF_00979 8.2e-106 yhfK GM NmrA-like family
OFLKEHFF_00980 1.7e-295 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OFLKEHFF_00981 3.1e-63 yhfM
OFLKEHFF_00982 7.9e-230 yhfN 3.4.24.84 O Peptidase M48
OFLKEHFF_00983 2.1e-200 aprE 3.4.21.62 O Belongs to the peptidase S8 family
OFLKEHFF_00984 8.2e-133 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
OFLKEHFF_00985 2.2e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
OFLKEHFF_00986 3.4e-197 vraB 2.3.1.9 I Belongs to the thiolase family
OFLKEHFF_00987 1.6e-263 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OFLKEHFF_00988 3.1e-85 bioY S BioY family
OFLKEHFF_00989 4.1e-197 hemAT NT chemotaxis protein
OFLKEHFF_00990 7.7e-288 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OFLKEHFF_00991 3.2e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFLKEHFF_00992 3.5e-30 yhzC S IDEAL
OFLKEHFF_00993 4.2e-109 comK K Competence transcription factor
OFLKEHFF_00994 2.2e-55 frataxin S Domain of unknown function (DU1801)
OFLKEHFF_00995 4e-170 els S Acetyltransferase, GNAT family
OFLKEHFF_00996 9.9e-121 yrpD S Domain of unknown function, YrpD
OFLKEHFF_00997 1.7e-41 yhjA S Excalibur calcium-binding domain
OFLKEHFF_00998 3.3e-47 S Belongs to the UPF0145 family
OFLKEHFF_00999 4.9e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OFLKEHFF_01000 2.4e-27 yhjC S Protein of unknown function (DUF3311)
OFLKEHFF_01001 3.2e-59 yhjD
OFLKEHFF_01002 4.2e-107 yhjE S SNARE associated Golgi protein
OFLKEHFF_01003 6.6e-90 sipV 3.4.21.89 U Belongs to the peptidase S26 family
OFLKEHFF_01004 1.1e-263 yhjG CH FAD binding domain
OFLKEHFF_01005 2.1e-91 yhjH K helix_turn_helix multiple antibiotic resistance protein
OFLKEHFF_01006 1.1e-182 abrB S membrane
OFLKEHFF_01007 9.9e-198 blt EGP Major facilitator Superfamily
OFLKEHFF_01008 2.1e-106 K QacR-like protein, C-terminal region
OFLKEHFF_01009 1.8e-82 yhjR S Rubrerythrin
OFLKEHFF_01010 2.5e-119 ydfS S Protein of unknown function (DUF421)
OFLKEHFF_01011 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
OFLKEHFF_01012 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OFLKEHFF_01013 1.2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OFLKEHFF_01014 0.0 sbcC L COG0419 ATPase involved in DNA repair
OFLKEHFF_01015 3.9e-50 yisB V COG1403 Restriction endonuclease
OFLKEHFF_01016 1.7e-31 gerPF S Spore germination protein gerPA/gerPF
OFLKEHFF_01017 3.5e-59 gerPE S Spore germination protein GerPE
OFLKEHFF_01018 7.7e-22 gerPD S Spore germination protein
OFLKEHFF_01019 5.9e-61 gerPC S Spore germination protein
OFLKEHFF_01020 1.1e-31 gerPB S cell differentiation
OFLKEHFF_01021 8.4e-34 gerPA S Spore germination protein
OFLKEHFF_01022 1.2e-08 yisI S Spo0E like sporulation regulatory protein
OFLKEHFF_01023 7.6e-166 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OFLKEHFF_01024 1.9e-59 yisL S UPF0344 protein
OFLKEHFF_01025 0.0 wprA O Belongs to the peptidase S8 family
OFLKEHFF_01026 5.3e-90 yisN S Protein of unknown function (DUF2777)
OFLKEHFF_01027 0.0 asnO 6.3.5.4 E Asparagine synthase
OFLKEHFF_01028 1e-115 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
OFLKEHFF_01029 5.9e-242 yisQ V Mate efflux family protein
OFLKEHFF_01030 1.8e-156 yisR K Transcriptional regulator
OFLKEHFF_01031 1.3e-142 purR K helix_turn _helix lactose operon repressor
OFLKEHFF_01032 2.4e-155 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
OFLKEHFF_01033 9.2e-79 yisT S DinB family
OFLKEHFF_01034 2.3e-25 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFLKEHFF_01035 2.1e-29 mcbG S Pentapeptide repeats (9 copies)
OFLKEHFF_01036 2.5e-42 yjcF S Acetyltransferase (GNAT) domain
OFLKEHFF_01037 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OFLKEHFF_01038 1.9e-54 yajQ S Belongs to the UPF0234 family
OFLKEHFF_01039 2.3e-156 cvfB S protein conserved in bacteria
OFLKEHFF_01040 3.2e-146 yufN S ABC transporter substrate-binding protein PnrA-like
OFLKEHFF_01041 2.2e-203 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
OFLKEHFF_01042 1.6e-235 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
OFLKEHFF_01044 1.4e-153 yitS S protein conserved in bacteria
OFLKEHFF_01045 8.7e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
OFLKEHFF_01046 7.2e-80 ipi S Intracellular proteinase inhibitor
OFLKEHFF_01047 9.8e-26 S Protein of unknown function (DUF3813)
OFLKEHFF_01048 2.6e-07
OFLKEHFF_01049 3.1e-150 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OFLKEHFF_01050 3.2e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
OFLKEHFF_01051 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
OFLKEHFF_01052 4.7e-65 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
OFLKEHFF_01053 6.6e-265 yitY C D-arabinono-1,4-lactone oxidase
OFLKEHFF_01054 1.6e-86 norB G Major Facilitator Superfamily
OFLKEHFF_01055 9.2e-192 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OFLKEHFF_01056 1.2e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OFLKEHFF_01057 2.2e-129 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
OFLKEHFF_01058 2.1e-208 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OFLKEHFF_01059 3.7e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OFLKEHFF_01060 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
OFLKEHFF_01061 6.8e-173 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OFLKEHFF_01062 6.2e-27 yjzC S YjzC-like protein
OFLKEHFF_01063 6.3e-22 yjzD S Protein of unknown function (DUF2929)
OFLKEHFF_01064 1.8e-133 yjaU I carboxylic ester hydrolase activity
OFLKEHFF_01065 7.2e-98 yjaV
OFLKEHFF_01066 2e-163 med S Transcriptional activator protein med
OFLKEHFF_01067 3.3e-26 comZ S ComZ
OFLKEHFF_01069 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OFLKEHFF_01070 2.4e-231 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OFLKEHFF_01071 1.1e-139 yjaZ O Zn-dependent protease
OFLKEHFF_01072 2.2e-179 appD P Belongs to the ABC transporter superfamily
OFLKEHFF_01073 7.5e-183 appF E Belongs to the ABC transporter superfamily
OFLKEHFF_01074 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
OFLKEHFF_01075 4.8e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFLKEHFF_01076 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFLKEHFF_01077 5.5e-146 yjbA S Belongs to the UPF0736 family
OFLKEHFF_01078 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OFLKEHFF_01079 1.2e-307 oppA E ABC transporter substrate-binding protein
OFLKEHFF_01080 1.1e-164 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFLKEHFF_01081 5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFLKEHFF_01082 1.2e-199 oppD P Belongs to the ABC transporter superfamily
OFLKEHFF_01083 1.8e-170 oppF E Belongs to the ABC transporter superfamily
OFLKEHFF_01084 5.7e-222 S Putative glycosyl hydrolase domain
OFLKEHFF_01085 2.9e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFLKEHFF_01086 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OFLKEHFF_01087 4.7e-109 yjbE P Integral membrane protein TerC family
OFLKEHFF_01088 3.2e-109 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OFLKEHFF_01089 3.2e-201 yjbF S Competence protein
OFLKEHFF_01090 0.0 pepF E oligoendopeptidase F
OFLKEHFF_01091 9.8e-19
OFLKEHFF_01092 2.6e-166 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OFLKEHFF_01093 2.2e-69 yjbI S Bacterial-like globin
OFLKEHFF_01094 1.2e-102 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OFLKEHFF_01095 2.4e-93 yjbK S protein conserved in bacteria
OFLKEHFF_01096 5e-60 yjbL S Belongs to the UPF0738 family
OFLKEHFF_01097 1.9e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
OFLKEHFF_01098 3.9e-150 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OFLKEHFF_01099 2.6e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OFLKEHFF_01100 5e-139 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OFLKEHFF_01101 9e-307 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OFLKEHFF_01102 8.7e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OFLKEHFF_01103 9.6e-104 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
OFLKEHFF_01104 6.2e-202 thiO 1.4.3.19 E Glycine oxidase
OFLKEHFF_01105 2.6e-29 thiS H Thiamine biosynthesis
OFLKEHFF_01106 2.9e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
OFLKEHFF_01107 1.9e-178 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OFLKEHFF_01108 2.6e-141 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OFLKEHFF_01109 6.8e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OFLKEHFF_01110 1.4e-67 yjbX S Spore coat protein
OFLKEHFF_01111 3.1e-80 cotZ S Spore coat protein
OFLKEHFF_01112 1.3e-92 cotY S Spore coat protein Z
OFLKEHFF_01113 4.9e-66 cotX S Spore Coat Protein X and V domain
OFLKEHFF_01114 1.8e-26 cotW
OFLKEHFF_01115 6.3e-53 cotV S Spore Coat Protein X and V domain
OFLKEHFF_01116 6.2e-55 yjcA S Protein of unknown function (DUF1360)
OFLKEHFF_01120 2.4e-37 spoVIF S Stage VI sporulation protein F
OFLKEHFF_01121 0.0 yjcD 3.6.4.12 L DNA helicase
OFLKEHFF_01122 6.2e-33
OFLKEHFF_01123 7e-133 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
OFLKEHFF_01124 1.5e-107 S ABC-2 type transporter
OFLKEHFF_01125 1.5e-62 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
OFLKEHFF_01126 4.2e-54 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
OFLKEHFF_01127 7.6e-33 K SpoVT / AbrB like domain
OFLKEHFF_01128 6.8e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFLKEHFF_01129 1.2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
OFLKEHFF_01130 1.8e-122 yjcH P COG2382 Enterochelin esterase and related enzymes
OFLKEHFF_01131 1.3e-210 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OFLKEHFF_01132 2e-214 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OFLKEHFF_01134 4.9e-21
OFLKEHFF_01137 5.8e-08 tnpB L Belongs to the 'phage' integrase family
OFLKEHFF_01138 1.5e-29 tnpB L Belongs to the 'phage' integrase family
OFLKEHFF_01139 5.6e-22 tnpC S Transposition regulatory protein TnpC
OFLKEHFF_01140 1.1e-20 yxbF K Transcriptional regulator C-terminal region
OFLKEHFF_01141 7.7e-57 1.1.1.169, 1.3.1.12, 4.2.1.51, 5.4.99.5 E PFAM Ketopantoate reductase
OFLKEHFF_01145 4e-154 bla 3.5.2.6 V beta-lactamase
OFLKEHFF_01146 4.6e-45 yjcS S Antibiotic biosynthesis monooxygenase
OFLKEHFF_01147 1.2e-239 yfjF EGP Belongs to the major facilitator superfamily
OFLKEHFF_01148 3e-76 napB K helix_turn_helix multiple antibiotic resistance protein
OFLKEHFF_01150 4.9e-103 yhiD S MgtC SapB transporter
OFLKEHFF_01152 7.1e-20 yjfB S Putative motility protein
OFLKEHFF_01153 9.4e-60 T PhoQ Sensor
OFLKEHFF_01154 8.3e-94 yjgB S Domain of unknown function (DUF4309)
OFLKEHFF_01155 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OFLKEHFF_01156 1.2e-86 yjgD S Protein of unknown function (DUF1641)
OFLKEHFF_01157 5.3e-215 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
OFLKEHFF_01158 6.3e-213 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OFLKEHFF_01159 6.8e-29
OFLKEHFF_01160 7.2e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OFLKEHFF_01161 2.2e-118 ybbM S transport system, permease component
OFLKEHFF_01162 2.4e-125 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
OFLKEHFF_01163 7.7e-172 yjlA EG Putative multidrug resistance efflux transporter
OFLKEHFF_01164 1.1e-81 yjlB S Cupin domain
OFLKEHFF_01165 7e-66 yjlC S Protein of unknown function (DUF1641)
OFLKEHFF_01166 3.2e-217 yjlD 1.6.99.3 C NADH dehydrogenase
OFLKEHFF_01167 4.5e-90 yjmB G symporter YjmB
OFLKEHFF_01168 2.7e-180 exuR K transcriptional
OFLKEHFF_01170 4.2e-150 uxaA 4.2.1.7, 4.4.1.24 G Altronate
OFLKEHFF_01171 1.4e-128 MA20_18170 S membrane transporter protein
OFLKEHFF_01172 1.1e-75 yjoA S DinB family
OFLKEHFF_01173 6e-213 S response regulator aspartate phosphatase
OFLKEHFF_01175 1e-160 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OFLKEHFF_01176 2.6e-59 yjqA S Bacterial PH domain
OFLKEHFF_01177 2e-98 yjqB S phage-related replication protein
OFLKEHFF_01178 1.5e-106 xkdA E IrrE N-terminal-like domain
OFLKEHFF_01179 2.6e-55 xre K Helix-turn-helix XRE-family like proteins
OFLKEHFF_01181 7.2e-144 xkdC L Bacterial dnaA protein
OFLKEHFF_01184 7.8e-10 yqaO S Phage-like element PBSX protein XtrA
OFLKEHFF_01185 8.5e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OFLKEHFF_01186 9.2e-107 xtmA L phage terminase small subunit
OFLKEHFF_01187 5e-211 xtmB S phage terminase, large subunit
OFLKEHFF_01188 6.7e-241 yqbA S portal protein
OFLKEHFF_01189 5.2e-92 xkdF 2.1.1.72 L Putative phage serine protease XkdF
OFLKEHFF_01190 3e-157 xkdG S Phage capsid family
OFLKEHFF_01191 1.7e-45 yqbG S Protein of unknown function (DUF3199)
OFLKEHFF_01192 9.6e-40 yqbH S Domain of unknown function (DUF3599)
OFLKEHFF_01193 9.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
OFLKEHFF_01194 1.2e-58 xkdJ
OFLKEHFF_01195 1.8e-14
OFLKEHFF_01196 6.5e-225 xkdK S Phage tail sheath C-terminal domain
OFLKEHFF_01197 2e-74 xkdM S Phage tail tube protein
OFLKEHFF_01198 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
OFLKEHFF_01199 3.4e-19
OFLKEHFF_01200 2.4e-192 xkdO L Transglycosylase SLT domain
OFLKEHFF_01201 1.3e-111 xkdP S Lysin motif
OFLKEHFF_01202 3.8e-163 xkdQ 3.2.1.96 G NLP P60 protein
OFLKEHFF_01203 7.2e-32 xkdR S Protein of unknown function (DUF2577)
OFLKEHFF_01204 2.1e-57 xkdS S Protein of unknown function (DUF2634)
OFLKEHFF_01205 4.3e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OFLKEHFF_01206 1.6e-84 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OFLKEHFF_01207 6.1e-26
OFLKEHFF_01208 4.2e-161
OFLKEHFF_01210 6.8e-27 xkdX
OFLKEHFF_01211 3.7e-129 xepA
OFLKEHFF_01212 7.4e-37 xhlA S Haemolysin XhlA
OFLKEHFF_01213 4.3e-37 xhlB S SPP1 phage holin
OFLKEHFF_01214 2.9e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFLKEHFF_01215 8.7e-23 spoIISB S Stage II sporulation protein SB
OFLKEHFF_01216 1.1e-130 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
OFLKEHFF_01217 4.1e-173 pit P phosphate transporter
OFLKEHFF_01218 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
OFLKEHFF_01219 2.3e-240 steT E amino acid
OFLKEHFF_01220 3.4e-177 mhqA E COG0346 Lactoylglutathione lyase and related lyases
OFLKEHFF_01221 3.4e-297 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OFLKEHFF_01222 5.6e-175 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OFLKEHFF_01224 3.9e-198 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OFLKEHFF_01225 7.4e-262 yubD P Major Facilitator Superfamily
OFLKEHFF_01226 1e-153 dppA E D-aminopeptidase
OFLKEHFF_01227 1.3e-157 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFLKEHFF_01228 6.3e-171 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OFLKEHFF_01229 9.2e-184 dppD P Belongs to the ABC transporter superfamily
OFLKEHFF_01230 9.3e-308 dppE E ABC transporter substrate-binding protein
OFLKEHFF_01231 3e-173 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OFLKEHFF_01232 2.7e-189 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OFLKEHFF_01233 4.4e-158 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OFLKEHFF_01234 3.8e-179 ykfD E Belongs to the ABC transporter superfamily
OFLKEHFF_01235 1.2e-199 pgl 3.1.1.31 G 6-phosphogluconolactonase
OFLKEHFF_01236 8e-133 ykgA E Amidinotransferase
OFLKEHFF_01237 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
OFLKEHFF_01238 2.7e-94 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OFLKEHFF_01239 4.1e-49 ykkC P Multidrug resistance protein
OFLKEHFF_01240 1.7e-48 ykkD P Multidrug resistance protein
OFLKEHFF_01241 5.2e-167 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
OFLKEHFF_01242 5.8e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OFLKEHFF_01243 1.1e-220 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OFLKEHFF_01244 1.2e-68 ohrA O Organic hydroperoxide resistance protein
OFLKEHFF_01245 6.8e-79 ohrR K COG1846 Transcriptional regulators
OFLKEHFF_01246 8.7e-69 ohrB O Organic hydroperoxide resistance protein
OFLKEHFF_01247 1.9e-42 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OFLKEHFF_01249 4.2e-206 M Glycosyl transferase family 2
OFLKEHFF_01250 5.6e-98 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
OFLKEHFF_01251 3e-207 hcaT 1.5.1.2 EGP Major facilitator Superfamily
OFLKEHFF_01252 6.4e-117 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
OFLKEHFF_01253 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OFLKEHFF_01254 1.2e-172 isp O Belongs to the peptidase S8 family
OFLKEHFF_01255 4.3e-139 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OFLKEHFF_01256 9.3e-125 ykoC P Cobalt transport protein
OFLKEHFF_01257 4.9e-280 P ABC transporter, ATP-binding protein
OFLKEHFF_01258 6.1e-95 ykoE S ABC-type cobalt transport system, permease component
OFLKEHFF_01259 6.7e-237 ydhD M Glycosyl hydrolase
OFLKEHFF_01261 1.8e-235 mgtE P Acts as a magnesium transporter
OFLKEHFF_01262 1.6e-52 tnrA K transcriptional
OFLKEHFF_01263 3.8e-17
OFLKEHFF_01264 5.9e-25 ykoL
OFLKEHFF_01265 4.2e-80 ykoM K transcriptional
OFLKEHFF_01266 3.2e-98 ykoP G polysaccharide deacetylase
OFLKEHFF_01267 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
OFLKEHFF_01268 7.4e-150 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OFLKEHFF_01269 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
OFLKEHFF_01270 4.7e-93 ykoX S membrane-associated protein
OFLKEHFF_01271 9.2e-128 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OFLKEHFF_01272 7.6e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFLKEHFF_01273 3.4e-118 rsgI S Anti-sigma factor N-terminus
OFLKEHFF_01274 9.6e-26 sspD S small acid-soluble spore protein
OFLKEHFF_01275 9.5e-124 ykrK S Domain of unknown function (DUF1836)
OFLKEHFF_01276 1.7e-154 htpX O Belongs to the peptidase M48B family
OFLKEHFF_01277 2.7e-236 ktrB P COG0168 Trk-type K transport systems, membrane components
OFLKEHFF_01278 1.4e-111 ydfR S Protein of unknown function (DUF421)
OFLKEHFF_01279 1.2e-19 ykzE
OFLKEHFF_01280 3.2e-181 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
OFLKEHFF_01281 0.0 kinE 2.7.13.3 T Histidine kinase
OFLKEHFF_01282 9.2e-81 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OFLKEHFF_01284 3.8e-193 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OFLKEHFF_01285 9.1e-220 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OFLKEHFF_01286 3.3e-138 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OFLKEHFF_01287 3.7e-221 mtnE 2.6.1.83 E Aminotransferase
OFLKEHFF_01288 2.6e-222 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
OFLKEHFF_01289 5e-133 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OFLKEHFF_01290 2.4e-110 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
OFLKEHFF_01291 4.3e-92 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OFLKEHFF_01292 1.8e-11 S Spo0E like sporulation regulatory protein
OFLKEHFF_01293 3.2e-270 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
OFLKEHFF_01294 1.6e-76 ykvE K transcriptional
OFLKEHFF_01295 1e-121 motB N Flagellar motor protein
OFLKEHFF_01296 1.4e-134 motA N flagellar motor
OFLKEHFF_01297 0.0 clpE O Belongs to the ClpA ClpB family
OFLKEHFF_01298 3.8e-177 ykvI S membrane
OFLKEHFF_01299 2.3e-172
OFLKEHFF_01300 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OFLKEHFF_01301 1.7e-78 queD 4.1.2.50, 4.2.3.12 H synthase
OFLKEHFF_01302 1.2e-137 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OFLKEHFF_01303 1.3e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OFLKEHFF_01304 3e-41 ykvR S Protein of unknown function (DUF3219)
OFLKEHFF_01305 1.7e-24 ykvS S protein conserved in bacteria
OFLKEHFF_01306 2.3e-27
OFLKEHFF_01307 1.1e-104 ykvT 3.5.1.28 M Cell Wall Hydrolase
OFLKEHFF_01308 1.6e-236 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFLKEHFF_01309 7.5e-83 stoA CO thiol-disulfide
OFLKEHFF_01310 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OFLKEHFF_01311 8.5e-204 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OFLKEHFF_01313 7.5e-172 ykvZ 5.1.1.1 K Transcriptional regulator
OFLKEHFF_01314 4e-153 glcT K antiterminator
OFLKEHFF_01315 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFLKEHFF_01316 2.1e-39 ptsH G phosphocarrier protein HPr
OFLKEHFF_01317 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OFLKEHFF_01318 6.7e-37 splA S Transcriptional regulator
OFLKEHFF_01319 1.8e-192 splB 4.1.99.14 L Spore photoproduct lyase
OFLKEHFF_01320 1.2e-254 mcpC NT chemotaxis protein
OFLKEHFF_01321 1.6e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OFLKEHFF_01322 2.2e-113 ykwD J protein with SCP PR1 domains
OFLKEHFF_01323 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
OFLKEHFF_01324 1.9e-288 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
OFLKEHFF_01325 4.3e-214 patA 2.6.1.1 E Aminotransferase
OFLKEHFF_01326 1.4e-09
OFLKEHFF_01327 1.7e-165 cheV 2.7.13.3 T Chemotaxis protein CheV
OFLKEHFF_01328 3.2e-83 ykyB S YkyB-like protein
OFLKEHFF_01329 5.3e-237 ykuC EGP Major facilitator Superfamily
OFLKEHFF_01330 7.8e-88 ykuD S protein conserved in bacteria
OFLKEHFF_01331 1.4e-145 ykuE S Metallophosphoesterase
OFLKEHFF_01332 2.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFLKEHFF_01333 6.9e-231 ykuI T Diguanylate phosphodiesterase
OFLKEHFF_01334 2e-36 ykuJ S protein conserved in bacteria
OFLKEHFF_01335 3e-90 ykuK S Ribonuclease H-like
OFLKEHFF_01336 7.3e-26 ykzF S Antirepressor AbbA
OFLKEHFF_01337 1e-75 ykuL S CBS domain
OFLKEHFF_01338 2.3e-167 ccpC K Transcriptional regulator
OFLKEHFF_01339 2.6e-85 fld C Flavodoxin
OFLKEHFF_01340 2.8e-160 ykuO
OFLKEHFF_01341 1.2e-74 fld C Flavodoxin
OFLKEHFF_01342 4.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OFLKEHFF_01343 1.5e-211 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OFLKEHFF_01344 1.8e-37 ykuS S Belongs to the UPF0180 family
OFLKEHFF_01345 1.6e-138 ykuT M Mechanosensitive ion channel
OFLKEHFF_01346 1.9e-72 ykuV CO thiol-disulfide
OFLKEHFF_01348 3.8e-97 rok K Repressor of ComK
OFLKEHFF_01349 8.1e-145 yknT
OFLKEHFF_01350 1.8e-99 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OFLKEHFF_01351 2e-186 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OFLKEHFF_01352 1.5e-239 moeA 2.10.1.1 H molybdopterin
OFLKEHFF_01353 4.5e-86 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
OFLKEHFF_01354 7.1e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
OFLKEHFF_01355 4.1e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OFLKEHFF_01356 1.5e-100 yknW S Yip1 domain
OFLKEHFF_01357 6.2e-157 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OFLKEHFF_01358 5.1e-122 macB V ABC transporter, ATP-binding protein
OFLKEHFF_01359 8.1e-208 yknZ V ABC transporter (permease)
OFLKEHFF_01360 9.5e-130 fruR K Transcriptional regulator
OFLKEHFF_01361 1.1e-164 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
OFLKEHFF_01362 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OFLKEHFF_01363 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OFLKEHFF_01364 4.9e-36 ykoA
OFLKEHFF_01365 3.2e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OFLKEHFF_01366 2e-158 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OFLKEHFF_01367 7.2e-236 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OFLKEHFF_01368 6.5e-13 S Uncharacterized protein YkpC
OFLKEHFF_01369 3.4e-183 mreB D Rod-share determining protein MreBH
OFLKEHFF_01370 1e-44 abrB K of stationary sporulation gene expression
OFLKEHFF_01371 4.5e-236 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
OFLKEHFF_01372 2.3e-145 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
OFLKEHFF_01373 2.6e-115 ktrA P COG0569 K transport systems, NAD-binding component
OFLKEHFF_01374 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OFLKEHFF_01375 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OFLKEHFF_01376 5.3e-30 ykzG S Belongs to the UPF0356 family
OFLKEHFF_01377 1.2e-140 ykrA S hydrolases of the HAD superfamily
OFLKEHFF_01378 1.4e-98 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OFLKEHFF_01380 6.6e-66 recN L Putative cell-wall binding lipoprotein
OFLKEHFF_01381 3.8e-183 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OFLKEHFF_01382 1.2e-177 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OFLKEHFF_01383 1.6e-225 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OFLKEHFF_01384 3.3e-240 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OFLKEHFF_01385 6.1e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
OFLKEHFF_01386 3.4e-125 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
OFLKEHFF_01387 1.3e-271 speA 4.1.1.19 E Arginine
OFLKEHFF_01388 3.5e-42 yktA S Belongs to the UPF0223 family
OFLKEHFF_01389 1.2e-117 yktB S Belongs to the UPF0637 family
OFLKEHFF_01390 6.3e-24 ykzI
OFLKEHFF_01391 1.5e-149 suhB 3.1.3.25 G Inositol monophosphatase
OFLKEHFF_01392 9.6e-77 ykzC S Acetyltransferase (GNAT) family
OFLKEHFF_01393 2.3e-287 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
OFLKEHFF_01394 4.4e-14 sigC S Putative zinc-finger
OFLKEHFF_01395 1.2e-37 ylaE
OFLKEHFF_01396 6.7e-24 S Family of unknown function (DUF5325)
OFLKEHFF_01397 0.0 typA T GTP-binding protein TypA
OFLKEHFF_01398 3e-48 ylaH S YlaH-like protein
OFLKEHFF_01399 1.5e-32 ylaI S protein conserved in bacteria
OFLKEHFF_01400 1.8e-97 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OFLKEHFF_01401 5e-243 phoH T ATPase related to phosphate starvation-inducible protein PhoH
OFLKEHFF_01402 2.2e-79 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OFLKEHFF_01403 1.5e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
OFLKEHFF_01404 8.7e-44 ylaN S Belongs to the UPF0358 family
OFLKEHFF_01405 1.3e-208 ftsW D Belongs to the SEDS family
OFLKEHFF_01406 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OFLKEHFF_01407 1.6e-163 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OFLKEHFF_01408 5.5e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OFLKEHFF_01409 3.4e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OFLKEHFF_01410 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OFLKEHFF_01411 1.5e-109 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OFLKEHFF_01412 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OFLKEHFF_01413 1.2e-160 ctaG S cytochrome c oxidase
OFLKEHFF_01414 1.8e-57 ylbA S YugN-like family
OFLKEHFF_01415 1.1e-72 ylbB T COG0517 FOG CBS domain
OFLKEHFF_01416 2.1e-191 ylbC S protein with SCP PR1 domains
OFLKEHFF_01417 5.1e-53 ylbD S Putative coat protein
OFLKEHFF_01418 8.8e-37 ylbE S YlbE-like protein
OFLKEHFF_01419 1.9e-69 ylbF S Belongs to the UPF0342 family
OFLKEHFF_01420 1e-41 ylbG S UPF0298 protein
OFLKEHFF_01421 2.1e-97 rsmD 2.1.1.171 L Methyltransferase
OFLKEHFF_01422 2.1e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OFLKEHFF_01423 9.8e-209 ylbJ S Sporulation integral membrane protein YlbJ
OFLKEHFF_01424 6.4e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
OFLKEHFF_01425 5.9e-183 ylbL T Belongs to the peptidase S16 family
OFLKEHFF_01426 3.3e-220 ylbM S Belongs to the UPF0348 family
OFLKEHFF_01427 1.6e-88 yceD S metal-binding, possibly nucleic acid-binding protein
OFLKEHFF_01428 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OFLKEHFF_01429 5e-70 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OFLKEHFF_01430 5.8e-88 ylbP K n-acetyltransferase
OFLKEHFF_01431 9.1e-151 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OFLKEHFF_01432 4.3e-300 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OFLKEHFF_01433 1.2e-77 mraZ K Belongs to the MraZ family
OFLKEHFF_01434 5.6e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OFLKEHFF_01435 2.4e-51 ftsL D Essential cell division protein
OFLKEHFF_01436 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OFLKEHFF_01437 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
OFLKEHFF_01438 3.7e-279 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OFLKEHFF_01439 1.4e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OFLKEHFF_01440 6.7e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OFLKEHFF_01441 2.2e-185 spoVE D Belongs to the SEDS family
OFLKEHFF_01442 4.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OFLKEHFF_01443 3.4e-166 murB 1.3.1.98 M cell wall formation
OFLKEHFF_01444 7.4e-125 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OFLKEHFF_01445 1.7e-227 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OFLKEHFF_01446 7.5e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OFLKEHFF_01447 2.2e-75 bpr O COG1404 Subtilisin-like serine proteases
OFLKEHFF_01448 0.0 bpr O COG1404 Subtilisin-like serine proteases
OFLKEHFF_01449 7.6e-153 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OFLKEHFF_01450 1.2e-116 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFLKEHFF_01451 3.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFLKEHFF_01452 3e-142 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OFLKEHFF_01453 2.2e-243 argE 3.5.1.16 E Acetylornithine deacetylase
OFLKEHFF_01454 2.2e-38 ylmC S sporulation protein
OFLKEHFF_01455 7.3e-155 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
OFLKEHFF_01456 8.2e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OFLKEHFF_01457 5.7e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OFLKEHFF_01458 5.2e-41 yggT S membrane
OFLKEHFF_01459 4.4e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
OFLKEHFF_01460 8.9e-68 divIVA D Cell division initiation protein
OFLKEHFF_01461 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OFLKEHFF_01462 3.8e-63 dksA T COG1734 DnaK suppressor protein
OFLKEHFF_01463 1.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OFLKEHFF_01464 4.3e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OFLKEHFF_01465 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OFLKEHFF_01466 9.1e-229 pyrP F Xanthine uracil
OFLKEHFF_01467 4.6e-163 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OFLKEHFF_01468 8.3e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OFLKEHFF_01469 6.3e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OFLKEHFF_01470 0.0 carB 6.3.5.5 F Belongs to the CarB family
OFLKEHFF_01471 7.9e-140 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OFLKEHFF_01472 1.2e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OFLKEHFF_01473 7.4e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OFLKEHFF_01474 8.9e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OFLKEHFF_01475 6.1e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OFLKEHFF_01476 1.6e-175 cysP P phosphate transporter
OFLKEHFF_01477 4.7e-221 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OFLKEHFF_01478 2.1e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
OFLKEHFF_01479 1.8e-139 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OFLKEHFF_01480 1.7e-137 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
OFLKEHFF_01481 2.2e-74 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
OFLKEHFF_01482 9.6e-270 amyA 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
OFLKEHFF_01483 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OFLKEHFF_01484 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
OFLKEHFF_01485 2.3e-151 yloC S stress-induced protein
OFLKEHFF_01486 1.5e-40 ylzA S Belongs to the UPF0296 family
OFLKEHFF_01487 8.9e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OFLKEHFF_01488 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OFLKEHFF_01489 6.5e-221 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OFLKEHFF_01490 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OFLKEHFF_01491 1.5e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OFLKEHFF_01492 6.4e-168 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OFLKEHFF_01493 3.2e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OFLKEHFF_01494 7.6e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OFLKEHFF_01495 3.9e-131 stp 3.1.3.16 T phosphatase
OFLKEHFF_01496 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OFLKEHFF_01497 1e-162 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OFLKEHFF_01498 1.3e-114 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OFLKEHFF_01499 2.2e-114 thiN 2.7.6.2 H thiamine pyrophosphokinase
OFLKEHFF_01500 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OFLKEHFF_01501 2.7e-58 asp S protein conserved in bacteria
OFLKEHFF_01502 1.3e-299 yloV S kinase related to dihydroxyacetone kinase
OFLKEHFF_01503 4.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
OFLKEHFF_01504 2.5e-153 sdaAA 4.3.1.17 E L-serine dehydratase
OFLKEHFF_01505 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OFLKEHFF_01506 2.2e-91 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OFLKEHFF_01507 1.1e-165 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OFLKEHFF_01508 1.2e-166 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OFLKEHFF_01509 1.5e-127 IQ reductase
OFLKEHFF_01510 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OFLKEHFF_01511 7.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OFLKEHFF_01512 0.0 smc D Required for chromosome condensation and partitioning
OFLKEHFF_01513 5.9e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OFLKEHFF_01514 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OFLKEHFF_01515 2.6e-231 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OFLKEHFF_01516 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OFLKEHFF_01517 1.7e-35 ylqC S Belongs to the UPF0109 family
OFLKEHFF_01518 1.1e-60 ylqD S YlqD protein
OFLKEHFF_01519 6.5e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OFLKEHFF_01520 9.5e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OFLKEHFF_01521 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OFLKEHFF_01522 6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OFLKEHFF_01523 6.1e-124 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OFLKEHFF_01524 2.9e-267 ylqG
OFLKEHFF_01525 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
OFLKEHFF_01526 7.6e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OFLKEHFF_01527 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OFLKEHFF_01528 6e-163 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
OFLKEHFF_01529 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OFLKEHFF_01530 5.3e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OFLKEHFF_01531 3.3e-169 xerC L tyrosine recombinase XerC
OFLKEHFF_01532 2.2e-91 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OFLKEHFF_01533 2.5e-232 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OFLKEHFF_01534 2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OFLKEHFF_01535 7.8e-51 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OFLKEHFF_01536 9.9e-74 flgC N Belongs to the flagella basal body rod proteins family
OFLKEHFF_01537 9.6e-31 fliE N Flagellar hook-basal body
OFLKEHFF_01538 3.7e-248 fliF N The M ring may be actively involved in energy transduction
OFLKEHFF_01539 1.7e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OFLKEHFF_01540 1.2e-84 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
OFLKEHFF_01541 9.4e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OFLKEHFF_01542 4.5e-71 fliJ N Flagellar biosynthesis chaperone
OFLKEHFF_01543 2.8e-39 ylxF S MgtE intracellular N domain
OFLKEHFF_01544 1.8e-187 fliK N Flagellar hook-length control protein
OFLKEHFF_01545 7e-69 flgD N Flagellar basal body rod modification protein
OFLKEHFF_01546 5.4e-136 flgG N Flagellar basal body rod
OFLKEHFF_01547 1.5e-55 fliL N Controls the rotational direction of flagella during chemotaxis
OFLKEHFF_01548 3.9e-179 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OFLKEHFF_01549 1.2e-176 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OFLKEHFF_01550 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
OFLKEHFF_01551 3.3e-110 fliZ N Flagellar biosynthesis protein, FliO
OFLKEHFF_01552 1.4e-108 fliP N Plays a role in the flagellum-specific transport system
OFLKEHFF_01553 7.5e-37 fliQ N Role in flagellar biosynthesis
OFLKEHFF_01554 4.9e-129 fliR N Flagellar biosynthetic protein FliR
OFLKEHFF_01555 1.9e-187 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OFLKEHFF_01556 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OFLKEHFF_01557 1e-148 flhF N Flagellar biosynthesis regulator FlhF
OFLKEHFF_01558 1.1e-153 flhG D Belongs to the ParA family
OFLKEHFF_01559 1.3e-185 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OFLKEHFF_01560 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
OFLKEHFF_01561 2.5e-80 cheW NT COG0835 Chemotaxis signal transduction protein
OFLKEHFF_01562 7e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OFLKEHFF_01563 1.2e-85 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OFLKEHFF_01564 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFLKEHFF_01565 8.3e-47 ylxL
OFLKEHFF_01566 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
OFLKEHFF_01567 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OFLKEHFF_01568 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OFLKEHFF_01569 2.1e-89 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OFLKEHFF_01570 1.3e-142 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OFLKEHFF_01571 8.4e-137 cdsA 2.7.7.41 S Belongs to the CDS family
OFLKEHFF_01572 8.9e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OFLKEHFF_01573 1.9e-231 rasP M zinc metalloprotease
OFLKEHFF_01574 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OFLKEHFF_01575 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OFLKEHFF_01576 1.9e-80 rimP S Required for maturation of 30S ribosomal subunits
OFLKEHFF_01577 1.2e-205 nusA K Participates in both transcription termination and antitermination
OFLKEHFF_01578 3.8e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
OFLKEHFF_01579 1.8e-47 ylxQ J ribosomal protein
OFLKEHFF_01580 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OFLKEHFF_01581 8.6e-44 ylxP S protein conserved in bacteria
OFLKEHFF_01582 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OFLKEHFF_01583 3.2e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OFLKEHFF_01584 2.3e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OFLKEHFF_01585 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OFLKEHFF_01586 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OFLKEHFF_01587 2.7e-177 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
OFLKEHFF_01588 3.7e-232 pepR S Belongs to the peptidase M16 family
OFLKEHFF_01589 2.6e-42 ymxH S YlmC YmxH family
OFLKEHFF_01590 6.3e-157 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
OFLKEHFF_01591 5e-102 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OFLKEHFF_01592 1.5e-189 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OFLKEHFF_01593 7.4e-217 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OFLKEHFF_01594 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OFLKEHFF_01595 2.9e-304 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OFLKEHFF_01596 2.4e-121 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
OFLKEHFF_01597 2.6e-29 S YlzJ-like protein
OFLKEHFF_01598 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OFLKEHFF_01599 2.7e-129 ymfC K Transcriptional regulator
OFLKEHFF_01600 6.9e-224 ymfD EGP Major facilitator Superfamily
OFLKEHFF_01601 1.5e-74 K helix_turn_helix multiple antibiotic resistance protein
OFLKEHFF_01602 0.0 ydgH S drug exporters of the RND superfamily
OFLKEHFF_01603 1.3e-232 ymfF S Peptidase M16
OFLKEHFF_01604 1.9e-239 ymfH S zinc protease
OFLKEHFF_01605 9.5e-127 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OFLKEHFF_01606 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
OFLKEHFF_01607 2.3e-142 ymfK S Protein of unknown function (DUF3388)
OFLKEHFF_01608 1.8e-119 ymfM S protein conserved in bacteria
OFLKEHFF_01609 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OFLKEHFF_01610 9.3e-231 cinA 3.5.1.42 S Belongs to the CinA family
OFLKEHFF_01611 7.6e-186 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OFLKEHFF_01612 9.2e-180 pbpX V Beta-lactamase
OFLKEHFF_01613 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
OFLKEHFF_01614 1.9e-152 ymdB S protein conserved in bacteria
OFLKEHFF_01615 1.2e-36 spoVS S Stage V sporulation protein S
OFLKEHFF_01616 3.4e-194 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
OFLKEHFF_01617 3.7e-213 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OFLKEHFF_01618 3.2e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OFLKEHFF_01619 5.6e-66 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OFLKEHFF_01620 6.1e-86 cotE S Spore coat protein
OFLKEHFF_01621 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OFLKEHFF_01622 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OFLKEHFF_01623 1.7e-135 L Belongs to the 'phage' integrase family
OFLKEHFF_01624 9.9e-40 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
OFLKEHFF_01625 3.4e-76 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
OFLKEHFF_01627 6.4e-46
OFLKEHFF_01629 5.3e-19 V VanZ like family
OFLKEHFF_01630 2.2e-58 E Glyoxalase-like domain
OFLKEHFF_01632 3e-49 wecC 1.1.1.336 M ArpU family transcriptional regulator
OFLKEHFF_01633 5e-15
OFLKEHFF_01634 1.2e-40
OFLKEHFF_01635 1.8e-10 A Pre-toxin TG
OFLKEHFF_01636 9.6e-34 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OFLKEHFF_01637 1.2e-35 yobL L nucleic acid phosphodiester bond hydrolysis
OFLKEHFF_01638 2.9e-125 pksB 3.1.2.6 S Polyketide biosynthesis
OFLKEHFF_01639 2.8e-157 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OFLKEHFF_01640 4.5e-172 pksD Q Acyl transferase domain
OFLKEHFF_01641 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OFLKEHFF_01642 1.1e-34 acpK IQ Phosphopantetheine attachment site
OFLKEHFF_01643 5.9e-241 pksG 2.3.3.10 I synthase
OFLKEHFF_01644 3.3e-138 pksH 4.2.1.18 I enoyl-CoA hydratase
OFLKEHFF_01645 3.6e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
OFLKEHFF_01646 0.0 rhiB IQ polyketide synthase
OFLKEHFF_01647 0.0 Q Polyketide synthase of type I
OFLKEHFF_01648 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
OFLKEHFF_01649 0.0 dhbF IQ polyketide synthase
OFLKEHFF_01650 0.0 pks13 HQ Beta-ketoacyl synthase
OFLKEHFF_01651 3.1e-223 cypA C Cytochrome P450
OFLKEHFF_01652 4.7e-73 nucB M Deoxyribonuclease NucA/NucB
OFLKEHFF_01653 1e-114 yoaK S Membrane
OFLKEHFF_01654 4.5e-61 ymzB
OFLKEHFF_01655 2.3e-248 aprX O Belongs to the peptidase S8 family
OFLKEHFF_01657 3.5e-118 ymaC S Replication protein
OFLKEHFF_01658 6.2e-76 ymaD O redox protein, regulator of disulfide bond formation
OFLKEHFF_01659 6.4e-52 ebrB P Small Multidrug Resistance protein
OFLKEHFF_01660 8.5e-48 ebrA P Small Multidrug Resistance protein
OFLKEHFF_01662 1.8e-42 ymaF S YmaF family
OFLKEHFF_01663 5.1e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OFLKEHFF_01664 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OFLKEHFF_01665 7.4e-40
OFLKEHFF_01666 1.8e-20 ymzA
OFLKEHFF_01667 2.3e-58 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OFLKEHFF_01668 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFLKEHFF_01669 2.6e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFLKEHFF_01670 2.4e-102 ymaB S MutT family
OFLKEHFF_01671 1.6e-105 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFLKEHFF_01672 8.6e-176 spoVK O stage V sporulation protein K
OFLKEHFF_01673 1.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OFLKEHFF_01674 5e-240 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OFLKEHFF_01675 1.6e-67 glnR K transcriptional
OFLKEHFF_01676 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
OFLKEHFF_01677 1.1e-115 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
OFLKEHFF_01678 1.2e-211 cypA C Cytochrome P450
OFLKEHFF_01679 7.1e-248 xynT G MFS/sugar transport protein
OFLKEHFF_01680 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OFLKEHFF_01681 4.3e-206 xylR GK ROK family
OFLKEHFF_01682 6.4e-254 xylA 5.3.1.5 G Belongs to the xylose isomerase family
OFLKEHFF_01683 1.4e-273 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
OFLKEHFF_01684 1.7e-117 3.2.1.8 G Glycosyl hydrolases family 11
OFLKEHFF_01685 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
OFLKEHFF_01686 4.9e-88 K Transcriptional regulator, TetR family
OFLKEHFF_01687 3.1e-176 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OFLKEHFF_01689 2.5e-195 S aspartate phosphatase
OFLKEHFF_01692 7e-68 S DinB family
OFLKEHFF_01693 2e-181 adhP 1.1.1.1 C alcohol dehydrogenase
OFLKEHFF_01694 1.1e-45
OFLKEHFF_01695 2.1e-07
OFLKEHFF_01696 3.2e-25 S Protein of unknown function (DUF4025)
OFLKEHFF_01700 1.7e-17
OFLKEHFF_01701 1.2e-75 ynaE S Domain of unknown function (DUF3885)
OFLKEHFF_01702 2.9e-13 ynaE S Domain of unknown function (DUF3885)
OFLKEHFF_01703 5.4e-187 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFLKEHFF_01704 1.9e-115 AA10,CBM73 S Pfam:Chitin_bind_3
OFLKEHFF_01706 8.4e-88 yvgO
OFLKEHFF_01708 0.0 yobO M Pectate lyase superfamily protein
OFLKEHFF_01709 1.3e-32 S TM2 domain
OFLKEHFF_01710 1.1e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OFLKEHFF_01711 3.9e-129 yndL S Replication protein
OFLKEHFF_01713 6.8e-137 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
OFLKEHFF_01714 2.6e-66 yndM S Protein of unknown function (DUF2512)
OFLKEHFF_01715 1.7e-11 yoaW
OFLKEHFF_01716 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OFLKEHFF_01717 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OFLKEHFF_01718 4.2e-110 yneB L resolvase
OFLKEHFF_01719 9.8e-33 ynzC S UPF0291 protein
OFLKEHFF_01720 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OFLKEHFF_01721 7.7e-79 yneE S Sporulation inhibitor of replication protein sirA
OFLKEHFF_01722 2.3e-28 yneF S UPF0154 protein
OFLKEHFF_01723 8.9e-23 ynzD S Spo0E like sporulation regulatory protein
OFLKEHFF_01724 2e-121 ccdA O cytochrome c biogenesis protein
OFLKEHFF_01725 1.2e-56 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
OFLKEHFF_01726 2.1e-74 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
OFLKEHFF_01727 2.2e-70 yneK S Protein of unknown function (DUF2621)
OFLKEHFF_01728 1.9e-59 hspX O Spore coat protein
OFLKEHFF_01729 2.3e-19 sspP S Belongs to the SspP family
OFLKEHFF_01730 7.5e-15 sspO S Belongs to the SspO family
OFLKEHFF_01731 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OFLKEHFF_01732 4.7e-88 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OFLKEHFF_01735 5.9e-33 tlp S Belongs to the Tlp family
OFLKEHFF_01736 1e-72 yneP S Thioesterase-like superfamily
OFLKEHFF_01737 7.3e-49 yneQ
OFLKEHFF_01738 1.2e-43 yneR S Belongs to the HesB IscA family
OFLKEHFF_01739 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OFLKEHFF_01740 1.2e-67 yccU S CoA-binding protein
OFLKEHFF_01741 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OFLKEHFF_01742 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OFLKEHFF_01743 4.6e-13
OFLKEHFF_01744 7.3e-40 ynfC
OFLKEHFF_01745 1.5e-245 agcS E Sodium alanine symporter
OFLKEHFF_01746 1.1e-27 kdgR_1 K transcriptional
OFLKEHFF_01747 3.2e-44 yndG S DoxX-like family
OFLKEHFF_01748 1.5e-44 yndG S DoxX-like family
OFLKEHFF_01749 1.6e-79 yndH S Domain of unknown function (DUF4166)
OFLKEHFF_01750 6.1e-275 yndJ S YndJ-like protein
OFLKEHFF_01751 1.1e-50 S Domain of unknown function (DUF4870)
OFLKEHFF_01752 3e-214 T PhoQ Sensor
OFLKEHFF_01753 5.2e-122 T Transcriptional regulatory protein, C terminal
OFLKEHFF_01754 4.2e-239 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
OFLKEHFF_01755 7.3e-278 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
OFLKEHFF_01756 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFLKEHFF_01757 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFLKEHFF_01758 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFLKEHFF_01759 3.7e-208 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OFLKEHFF_01760 1.5e-122 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OFLKEHFF_01761 3.7e-106 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OFLKEHFF_01762 2.3e-114 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OFLKEHFF_01763 5.3e-167 bioI 1.14.14.46 C Cytochrome P450
OFLKEHFF_01764 1.3e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OFLKEHFF_01765 4.4e-121 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OFLKEHFF_01766 6e-200 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OFLKEHFF_01767 7.9e-252 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
OFLKEHFF_01768 5.3e-136 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OFLKEHFF_01769 2.6e-65 yngA S membrane
OFLKEHFF_01770 3.3e-131 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OFLKEHFF_01771 1.6e-103 yngC S SNARE associated Golgi protein
OFLKEHFF_01772 1.1e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OFLKEHFF_01773 4.3e-133 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OFLKEHFF_01774 2.4e-164 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
OFLKEHFF_01775 1.6e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
OFLKEHFF_01776 2.9e-238 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
OFLKEHFF_01777 9.1e-311 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OFLKEHFF_01778 7e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
OFLKEHFF_01779 3.6e-293 yngK T Glycosyl hydrolase-like 10
OFLKEHFF_01780 1.7e-63 yngL S Protein of unknown function (DUF1360)
OFLKEHFF_01781 2.9e-48 Q D-alanine [D-alanyl carrier protein] ligase activity
OFLKEHFF_01782 2.3e-29 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFLKEHFF_01783 3.4e-256 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
OFLKEHFF_01784 2.9e-179 yoxA 5.1.3.3 G Aldose 1-epimerase
OFLKEHFF_01785 1.5e-242 yoeA V MATE efflux family protein
OFLKEHFF_01786 5.1e-93 yoeB S IseA DL-endopeptidase inhibitor
OFLKEHFF_01788 4.2e-95 L Integrase
OFLKEHFF_01789 3.3e-33 yoeD G Helix-turn-helix domain
OFLKEHFF_01790 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OFLKEHFF_01791 8.5e-194 ybcL EGP Major facilitator Superfamily
OFLKEHFF_01792 6.7e-50 ybzH K Helix-turn-helix domain
OFLKEHFF_01793 8.3e-271 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OFLKEHFF_01794 5.2e-134 gltR1 K Transcriptional regulator
OFLKEHFF_01795 1.4e-173 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
OFLKEHFF_01796 4.1e-48 1.16.3.1 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
OFLKEHFF_01797 3.6e-290 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OFLKEHFF_01798 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
OFLKEHFF_01799 6.9e-151 gltC K Transcriptional regulator
OFLKEHFF_01800 1.7e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OFLKEHFF_01801 1.9e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OFLKEHFF_01802 3.6e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OFLKEHFF_01803 4.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OFLKEHFF_01804 3.2e-36 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OFLKEHFF_01805 4.9e-118 yoxB
OFLKEHFF_01806 0.0 V Cell division protein FtsX
OFLKEHFF_01807 1.3e-109 V COG1136 ABC-type antimicrobial peptide transport system, ATPase component
OFLKEHFF_01808 2.8e-129 T PhoQ Sensor
OFLKEHFF_01809 5.5e-207 yoaB EGP Major facilitator Superfamily
OFLKEHFF_01810 5.4e-262 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
OFLKEHFF_01811 2.1e-185 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OFLKEHFF_01812 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OFLKEHFF_01813 2e-24 yoaF
OFLKEHFF_01817 1.6e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
OFLKEHFF_01818 1.3e-120 yobQ K helix_turn_helix, arabinose operon control protein
OFLKEHFF_01819 5e-83 yobS K Transcriptional regulator
OFLKEHFF_01820 5.2e-125 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
OFLKEHFF_01821 7.9e-91 yobW
OFLKEHFF_01822 3.8e-54 czrA K transcriptional
OFLKEHFF_01823 9.4e-105 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OFLKEHFF_01824 1.4e-90 yozB S membrane
OFLKEHFF_01825 5.6e-133 yocB J Protein required for attachment to host cells
OFLKEHFF_01826 4e-92 yocC
OFLKEHFF_01827 5.1e-184 yocD 3.4.17.13 V peptidase S66
OFLKEHFF_01829 2.1e-112 yocH CBM50 M COG1388 FOG LysM repeat
OFLKEHFF_01830 0.0 recQ 3.6.4.12 L DNA helicase
OFLKEHFF_01831 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OFLKEHFF_01832 4.1e-57 dksA T general stress protein
OFLKEHFF_01833 1.8e-09 yocL
OFLKEHFF_01834 4.4e-09
OFLKEHFF_01835 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
OFLKEHFF_01836 1.4e-43 yozN
OFLKEHFF_01837 2.5e-36 yocN
OFLKEHFF_01838 2.4e-56 yozO S Bacterial PH domain
OFLKEHFF_01840 1.6e-31 yozC
OFLKEHFF_01841 2.7e-285 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
OFLKEHFF_01842 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
OFLKEHFF_01843 8.1e-162 sodA 1.15.1.1 P Superoxide dismutase
OFLKEHFF_01844 4.2e-229 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OFLKEHFF_01845 2.9e-155 yocS S -transporter
OFLKEHFF_01846 6.1e-129 S Metallo-beta-lactamase superfamily
OFLKEHFF_01847 2.9e-184 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OFLKEHFF_01848 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OFLKEHFF_01849 0.0 yojO P Von Willebrand factor
OFLKEHFF_01850 1.3e-162 yojN S ATPase family associated with various cellular activities (AAA)
OFLKEHFF_01851 1.8e-104 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OFLKEHFF_01852 1.1e-212 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OFLKEHFF_01853 3.9e-218 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
OFLKEHFF_01854 8.8e-105 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OFLKEHFF_01856 7e-232 norM V Multidrug efflux pump
OFLKEHFF_01857 6.8e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OFLKEHFF_01858 1.3e-125 yojG S deacetylase
OFLKEHFF_01859 3.7e-60 yojF S Protein of unknown function (DUF1806)
OFLKEHFF_01860 8.4e-23
OFLKEHFF_01861 8.9e-159 rarD S -transporter
OFLKEHFF_01862 4e-78 yozR S COG0071 Molecular chaperone (small heat shock protein)
OFLKEHFF_01864 2e-62 yodA S tautomerase
OFLKEHFF_01865 3.5e-52 yodB K transcriptional
OFLKEHFF_01866 5.5e-104 yodC C nitroreductase
OFLKEHFF_01867 9.1e-107 mhqD S Carboxylesterase
OFLKEHFF_01868 2.2e-168 yodE E COG0346 Lactoylglutathione lyase and related lyases
OFLKEHFF_01869 3.1e-19 S Protein of unknown function (DUF3311)
OFLKEHFF_01870 9.3e-262 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OFLKEHFF_01871 5.2e-265 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
OFLKEHFF_01872 1.1e-283 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OFLKEHFF_01873 1.5e-127 yydK K Transcriptional regulator
OFLKEHFF_01874 1.2e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OFLKEHFF_01875 1.3e-120 yodH Q Methyltransferase
OFLKEHFF_01876 4.4e-23 yodI
OFLKEHFF_01877 1.8e-137 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OFLKEHFF_01878 7.7e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OFLKEHFF_01880 3.3e-55 yodL S YodL-like
OFLKEHFF_01881 2.9e-100 yodM 3.6.1.27 I Acid phosphatase homologues
OFLKEHFF_01882 1.8e-23 yozD S YozD-like protein
OFLKEHFF_01884 2.5e-121 yodN
OFLKEHFF_01885 1.6e-51 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFLKEHFF_01886 3.4e-35 yozE S Belongs to the UPF0346 family
OFLKEHFF_01887 3.9e-44 yokU S YokU-like protein, putative antitoxin
OFLKEHFF_01888 1.2e-274 kamA 5.4.3.2 E lysine 2,3-aminomutase
OFLKEHFF_01889 3e-140 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
OFLKEHFF_01890 6e-249 yodQ 3.5.1.16 E Acetylornithine deacetylase
OFLKEHFF_01891 4.8e-120 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OFLKEHFF_01892 1.1e-121 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OFLKEHFF_01893 3.3e-234 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OFLKEHFF_01895 5.8e-138 yiiD K acetyltransferase
OFLKEHFF_01896 1e-227 cgeD M maturation of the outermost layer of the spore
OFLKEHFF_01897 1.3e-34 cgeC
OFLKEHFF_01898 1.8e-48 cgeA
OFLKEHFF_01899 5.9e-169 cgeB S Spore maturation protein
OFLKEHFF_01900 3.7e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
OFLKEHFF_01901 9e-70 4.2.1.115 GM Polysaccharide biosynthesis protein
OFLKEHFF_01904 1.2e-120 lldD 1.13.12.4 C FMN-dependent dehydrogenase
OFLKEHFF_01906 3.2e-13 S Regulatory protein YrvL
OFLKEHFF_01907 2.4e-210 yokA L Recombinase
OFLKEHFF_01908 7.8e-100 4.2.1.115 GM Polysaccharide biosynthesis protein
OFLKEHFF_01909 2.2e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OFLKEHFF_01910 4.3e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OFLKEHFF_01911 3.1e-66 ypoP K transcriptional
OFLKEHFF_01912 2.2e-94 ypmS S protein conserved in bacteria
OFLKEHFF_01913 2.8e-129 ypmR E GDSL-like Lipase/Acylhydrolase
OFLKEHFF_01914 1.3e-102 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OFLKEHFF_01915 4.9e-38 ypmP S Protein of unknown function (DUF2535)
OFLKEHFF_01916 2.6e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OFLKEHFF_01917 3.8e-163 pspF K Transcriptional regulator
OFLKEHFF_01918 8.7e-108 hlyIII S protein, Hemolysin III
OFLKEHFF_01919 1.4e-107 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OFLKEHFF_01920 6.6e-84 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OFLKEHFF_01921 3.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OFLKEHFF_01922 2.1e-111 ypjP S YpjP-like protein
OFLKEHFF_01923 3.1e-128 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
OFLKEHFF_01924 1e-75 yphP S Belongs to the UPF0403 family
OFLKEHFF_01925 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OFLKEHFF_01926 1.9e-153 ypgR C COG0694 Thioredoxin-like proteins and domains
OFLKEHFF_01927 3.2e-91 ypgQ S phosphohydrolase
OFLKEHFF_01928 1.5e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OFLKEHFF_01929 1.8e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OFLKEHFF_01930 1.4e-212 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
OFLKEHFF_01931 1e-30 cspD K Cold-shock protein
OFLKEHFF_01932 1.1e-10 degR
OFLKEHFF_01933 2.3e-35 S Protein of unknown function (DUF2564)
OFLKEHFF_01934 3.7e-27 ypeQ S Zinc-finger
OFLKEHFF_01935 2.1e-118 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
OFLKEHFF_01936 5.2e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OFLKEHFF_01937 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
OFLKEHFF_01939 3e-159 polA 2.7.7.7 L 5'3' exonuclease
OFLKEHFF_01941 4.8e-33 ypbS S Protein of unknown function (DUF2533)
OFLKEHFF_01942 0.0 ypbR S Dynamin family
OFLKEHFF_01943 3.7e-85 ypbQ S protein conserved in bacteria
OFLKEHFF_01944 4.7e-194 bcsA Q Naringenin-chalcone synthase
OFLKEHFF_01945 1.8e-72 J Acetyltransferase (GNAT) domain
OFLKEHFF_01946 2.7e-27 K Helix-turn-helix domain
OFLKEHFF_01947 7.2e-15 S Membrane
OFLKEHFF_01948 1.7e-85 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
OFLKEHFF_01949 1.4e-58
OFLKEHFF_01951 1.6e-72 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFLKEHFF_01952 4.9e-59 S Pfam:Phage_holin_4_1
OFLKEHFF_01954 9.9e-08
OFLKEHFF_01955 3.1e-108 S Domain of unknown function (DUF2479)
OFLKEHFF_01956 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
OFLKEHFF_01957 1.5e-228 NU Prophage endopeptidase tail
OFLKEHFF_01958 8.5e-103 S Phage tail protein
OFLKEHFF_01959 0.0 D phage tail tape measure protein
OFLKEHFF_01961 6e-82 S Phage tail tube protein
OFLKEHFF_01963 1.7e-48 S Bacteriophage HK97-gp10, putative tail-component
OFLKEHFF_01964 2.9e-40 S Phage head-tail joining protein
OFLKEHFF_01965 2.6e-38 S Phage gp6-like head-tail connector protein
OFLKEHFF_01966 2.6e-23
OFLKEHFF_01967 2.3e-155 gp36 S capsid protein
OFLKEHFF_01968 3.8e-84 S peptidase activity
OFLKEHFF_01969 3.8e-171 S Phage portal protein
OFLKEHFF_01970 2.6e-300 S Terminase
OFLKEHFF_01971 2.2e-77 L phage terminase small subunit
OFLKEHFF_01975 1.4e-17 K Transcriptional regulator
OFLKEHFF_01977 3.9e-12 K Transcriptional regulator
OFLKEHFF_01979 2.1e-67 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OFLKEHFF_01982 2.2e-20 yqaO S Phage-like element PBSX protein XtrA
OFLKEHFF_01984 2.2e-59 rusA L Endodeoxyribonuclease RusA
OFLKEHFF_01986 8.8e-120 xkdC L IstB-like ATP binding protein
OFLKEHFF_01987 4.6e-78 3.1.3.16 L DnaD domain protein
OFLKEHFF_01989 3.3e-60 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
OFLKEHFF_01990 1.3e-99
OFLKEHFF_01994 2.9e-86
OFLKEHFF_01995 2.7e-71 S DNA binding
OFLKEHFF_01996 3.8e-32
OFLKEHFF_01997 1.1e-09 K transcriptional regulator with C-terminal CBS domains
OFLKEHFF_01998 9.6e-14 K Helix-turn-helix XRE-family like proteins
OFLKEHFF_01999 8e-139 L Belongs to the 'phage' integrase family
OFLKEHFF_02000 3e-232 pbuX F xanthine
OFLKEHFF_02001 3.8e-94 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OFLKEHFF_02002 1.2e-285 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OFLKEHFF_02003 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
OFLKEHFF_02005 6.6e-22 S YpzG-like protein
OFLKEHFF_02006 4e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OFLKEHFF_02007 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OFLKEHFF_02008 2e-97 ypsA S Belongs to the UPF0398 family
OFLKEHFF_02009 4e-29 cotD S Inner spore coat protein D
OFLKEHFF_02011 4.7e-227 yprB L RNase_H superfamily
OFLKEHFF_02012 1.3e-81 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OFLKEHFF_02013 1.6e-22
OFLKEHFF_02017 4.6e-40
OFLKEHFF_02018 5.1e-80 ftsK D FtsK/SpoIIIE family
OFLKEHFF_02020 7.7e-08 K Cro/C1-type HTH DNA-binding domain
OFLKEHFF_02022 1.9e-70 S Tetratricopeptide repeat
OFLKEHFF_02023 5.6e-80 K Helix-turn-helix domain
OFLKEHFF_02024 5e-09 K Helix-turn-helix XRE-family like proteins
OFLKEHFF_02025 7.7e-15 S YolD-like protein
OFLKEHFF_02027 5.3e-30 S Domain of unknown function (DUF4917)
OFLKEHFF_02028 3.1e-160 A Pre-toxin TG
OFLKEHFF_02029 8.9e-25
OFLKEHFF_02030 2e-108 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFLKEHFF_02031 1.5e-29 xhlB S SPP1 phage holin
OFLKEHFF_02034 3.4e-11
OFLKEHFF_02035 3.4e-71
OFLKEHFF_02036 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
OFLKEHFF_02037 5.9e-182 L Prophage endopeptidase tail
OFLKEHFF_02038 3.6e-106 S Phage tail protein
OFLKEHFF_02039 1.5e-107 D Phage tail tape measure protein
OFLKEHFF_02040 7.6e-26
OFLKEHFF_02041 2.6e-80 N phage major tail protein, phi13 family
OFLKEHFF_02042 4.1e-27
OFLKEHFF_02044 5.5e-32 S Phage head-tail joining protein
OFLKEHFF_02045 1.2e-15 S Phage gp6-like head-tail connector protein
OFLKEHFF_02046 3.9e-130 S Phage capsid family
OFLKEHFF_02047 7e-88 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
OFLKEHFF_02048 2.8e-124 S Phage portal protein
OFLKEHFF_02049 1.7e-230 L Terminase
OFLKEHFF_02050 8.4e-27 L Phage terminase, small subunit
OFLKEHFF_02051 3e-23
OFLKEHFF_02053 4.6e-14
OFLKEHFF_02054 6.6e-25 S Terminase
OFLKEHFF_02060 5.2e-113 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OFLKEHFF_02061 1.3e-177 M Parallel beta-helix repeats
OFLKEHFF_02062 9.9e-88 S Pfam:DUF867
OFLKEHFF_02066 1.7e-25
OFLKEHFF_02079 8.5e-28 S Domain of unknown function (DUF5052)
OFLKEHFF_02080 2.3e-12
OFLKEHFF_02082 2e-09
OFLKEHFF_02083 8.9e-185 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
OFLKEHFF_02085 2e-10 M 3D domain
OFLKEHFF_02088 1.1e-21
OFLKEHFF_02089 4.7e-287 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OFLKEHFF_02090 2.7e-14 K Sigma-70 region 2
OFLKEHFF_02092 0.0 L DNA primase activity
OFLKEHFF_02094 3.4e-212 ttrA1 L Type III restriction protein res subunit
OFLKEHFF_02098 7.1e-09 dnaN 2.7.7.7 L DNA-directed DNA polymerase activity
OFLKEHFF_02101 9.3e-101 L Calcineurin-like phosphoesterase superfamily domain
OFLKEHFF_02103 2.6e-75 L DNA recombination
OFLKEHFF_02105 1.2e-80 CP_0646 L AAA domain
OFLKEHFF_02106 7e-11
OFLKEHFF_02107 3.5e-13 K Helix-turn-helix XRE-family like proteins
OFLKEHFF_02108 7.5e-09 K Bacteriophage CI repressor helix-turn-helix domain
OFLKEHFF_02109 7.8e-178 L recombinase activity
OFLKEHFF_02110 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OFLKEHFF_02111 1.3e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OFLKEHFF_02112 5.5e-63 hspX O Belongs to the small heat shock protein (HSP20) family
OFLKEHFF_02113 5.9e-44 yppG S YppG-like protein
OFLKEHFF_02115 9.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
OFLKEHFF_02118 3.5e-177 yppC S Protein of unknown function (DUF2515)
OFLKEHFF_02119 1.2e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OFLKEHFF_02120 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OFLKEHFF_02121 6.1e-85 ypoC
OFLKEHFF_02122 1.2e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OFLKEHFF_02123 3.4e-129 dnaD L DNA replication protein DnaD
OFLKEHFF_02124 1.1e-250 asnS 6.1.1.22 J asparaginyl-tRNA
OFLKEHFF_02125 7.7e-219 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OFLKEHFF_02126 6.7e-76 ypmB S protein conserved in bacteria
OFLKEHFF_02127 6.7e-23 ypmA S Protein of unknown function (DUF4264)
OFLKEHFF_02128 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OFLKEHFF_02129 3.9e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OFLKEHFF_02130 3.7e-154 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OFLKEHFF_02131 3.1e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OFLKEHFF_02132 1.9e-178 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OFLKEHFF_02133 7.3e-209 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OFLKEHFF_02134 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
OFLKEHFF_02135 1.6e-126 bshB1 S proteins, LmbE homologs
OFLKEHFF_02136 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
OFLKEHFF_02137 3.8e-145 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OFLKEHFF_02138 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
OFLKEHFF_02139 4.7e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
OFLKEHFF_02140 1.3e-221 oxdC 4.1.1.2 G Oxalate decarboxylase
OFLKEHFF_02141 5.2e-139 ypjB S sporulation protein
OFLKEHFF_02142 2.6e-92 ypjA S membrane
OFLKEHFF_02143 5.7e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
OFLKEHFF_02144 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
OFLKEHFF_02145 8.7e-95 qcrA C Menaquinol-cytochrome c reductase
OFLKEHFF_02146 2.8e-73 ypiF S Protein of unknown function (DUF2487)
OFLKEHFF_02147 4.8e-99 ypiB S Belongs to the UPF0302 family
OFLKEHFF_02148 3e-229 S COG0457 FOG TPR repeat
OFLKEHFF_02149 2e-228 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OFLKEHFF_02150 4.7e-202 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OFLKEHFF_02151 9e-198 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OFLKEHFF_02152 1.2e-135 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OFLKEHFF_02153 6.2e-224 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OFLKEHFF_02154 2.9e-111 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
OFLKEHFF_02155 3e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
OFLKEHFF_02156 2.8e-153 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OFLKEHFF_02157 2.4e-284 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OFLKEHFF_02158 3.8e-58 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OFLKEHFF_02159 6.3e-199 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OFLKEHFF_02160 2.3e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OFLKEHFF_02161 2e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
OFLKEHFF_02162 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OFLKEHFF_02163 4.8e-196 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OFLKEHFF_02164 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OFLKEHFF_02165 1.5e-135 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OFLKEHFF_02166 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OFLKEHFF_02167 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
OFLKEHFF_02168 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OFLKEHFF_02169 1.4e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OFLKEHFF_02170 1.3e-10 yphF
OFLKEHFF_02171 6e-129 yphF
OFLKEHFF_02172 1.5e-16 yphE S Protein of unknown function (DUF2768)
OFLKEHFF_02173 1.4e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OFLKEHFF_02174 1.8e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OFLKEHFF_02175 1e-97 yphA
OFLKEHFF_02176 4.8e-08 S YpzI-like protein
OFLKEHFF_02177 2.4e-179 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OFLKEHFF_02178 5.6e-206 rpsA 1.17.7.4 J Ribosomal protein S1
OFLKEHFF_02179 2.6e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OFLKEHFF_02180 1.4e-12 S Family of unknown function (DUF5359)
OFLKEHFF_02181 1.7e-58 ypfA M Flagellar protein YcgR
OFLKEHFF_02182 1.6e-244 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
OFLKEHFF_02183 4e-148 sleB 3.5.1.28 M Spore cortex-lytic enzyme
OFLKEHFF_02184 1.1e-114 prsW S Involved in the degradation of specific anti-sigma factors
OFLKEHFF_02185 2.7e-185 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
OFLKEHFF_02186 3e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OFLKEHFF_02187 6.3e-105 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OFLKEHFF_02188 1.4e-139 ypbG S Calcineurin-like phosphoesterase superfamily domain
OFLKEHFF_02189 1.1e-83 ypbF S Protein of unknown function (DUF2663)
OFLKEHFF_02190 7.9e-63 ypbE M Lysin motif
OFLKEHFF_02191 5.4e-96 ypbD S metal-dependent membrane protease
OFLKEHFF_02192 3.9e-276 recQ 3.6.4.12 L DNA helicase
OFLKEHFF_02193 7e-187 ypbB 5.1.3.1 S protein conserved in bacteria
OFLKEHFF_02194 3.6e-41 fer C Ferredoxin
OFLKEHFF_02195 1.6e-92 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OFLKEHFF_02196 5.9e-291 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OFLKEHFF_02197 2.1e-170 rsiX
OFLKEHFF_02198 2.2e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
OFLKEHFF_02199 0.0 resE 2.7.13.3 T Histidine kinase
OFLKEHFF_02200 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFLKEHFF_02201 7.2e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OFLKEHFF_02202 6.5e-309 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OFLKEHFF_02203 8.1e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OFLKEHFF_02204 4.2e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OFLKEHFF_02205 3.8e-88 spmB S Spore maturation protein
OFLKEHFF_02206 1.7e-102 spmA S Spore maturation protein
OFLKEHFF_02207 2.4e-209 dacB 3.4.16.4 M Belongs to the peptidase S11 family
OFLKEHFF_02208 2.4e-81 ypuI S Protein of unknown function (DUF3907)
OFLKEHFF_02209 5.1e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OFLKEHFF_02210 2.3e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OFLKEHFF_02212 5.6e-89 ypuF S Domain of unknown function (DUF309)
OFLKEHFF_02213 5e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFLKEHFF_02214 5.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OFLKEHFF_02215 2.7e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OFLKEHFF_02216 2.7e-109 ribE 2.5.1.9 H Riboflavin synthase
OFLKEHFF_02217 3.6e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OFLKEHFF_02218 1.9e-45 ypuD
OFLKEHFF_02219 3.9e-96 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OFLKEHFF_02220 8.6e-79 ccdC1 O Protein of unknown function (DUF1453)
OFLKEHFF_02221 5.7e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OFLKEHFF_02222 4.4e-150 ypuA S Secreted protein
OFLKEHFF_02223 8e-249 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OFLKEHFF_02224 5.1e-268 spoVAF EG Stage V sporulation protein AF
OFLKEHFF_02225 5.7e-109 spoVAEA S stage V sporulation protein
OFLKEHFF_02226 3.8e-57 spoVAEB S stage V sporulation protein
OFLKEHFF_02227 2.7e-188 spoVAD I Stage V sporulation protein AD
OFLKEHFF_02228 1.3e-78 spoVAC S stage V sporulation protein AC
OFLKEHFF_02229 2.2e-67 spoVAB S Stage V sporulation protein AB
OFLKEHFF_02230 4.5e-109 spoVAA S Stage V sporulation protein AA
OFLKEHFF_02231 2e-135 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFLKEHFF_02232 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OFLKEHFF_02233 2.3e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
OFLKEHFF_02234 2.9e-210 dacF 3.4.16.4 M Belongs to the peptidase S11 family
OFLKEHFF_02235 4.2e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OFLKEHFF_02236 7e-228 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OFLKEHFF_02237 7.7e-163 xerD L recombinase XerD
OFLKEHFF_02238 6.4e-37 S Protein of unknown function (DUF4227)
OFLKEHFF_02239 2.7e-79 fur P Belongs to the Fur family
OFLKEHFF_02240 2.7e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OFLKEHFF_02241 2.6e-30 yqkK
OFLKEHFF_02242 3.9e-23
OFLKEHFF_02243 6.1e-241 mleA 1.1.1.38 C malic enzyme
OFLKEHFF_02244 1.9e-240 mleN C Na H antiporter
OFLKEHFF_02245 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
OFLKEHFF_02246 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase
OFLKEHFF_02247 5e-57 ansR K Transcriptional regulator
OFLKEHFF_02248 7.4e-214 yqxK 3.6.4.12 L DNA helicase
OFLKEHFF_02249 9e-93 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
OFLKEHFF_02251 5.2e-162 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
OFLKEHFF_02253 2.6e-166 yqkD S COG1073 Hydrolases of the alpha beta superfamily
OFLKEHFF_02254 3.2e-39 yqkC S Protein of unknown function (DUF2552)
OFLKEHFF_02255 1.6e-58 yqkB S Belongs to the HesB IscA family
OFLKEHFF_02256 5.6e-167 yqkA K GrpB protein
OFLKEHFF_02258 8.1e-87 yqjY K acetyltransferase
OFLKEHFF_02259 3.7e-232 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OFLKEHFF_02260 1.1e-56 S YolD-like protein
OFLKEHFF_02262 7.9e-146 yueF S transporter activity
OFLKEHFF_02264 5e-176 coaA 2.7.1.33 F Pantothenic acid kinase
OFLKEHFF_02265 3.1e-240 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
OFLKEHFF_02266 1.3e-137 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
OFLKEHFF_02267 3.9e-168 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
OFLKEHFF_02268 4.6e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OFLKEHFF_02269 7.9e-160 K LysR substrate binding domain
OFLKEHFF_02270 3.3e-47 S GlpM protein
OFLKEHFF_02271 4.1e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OFLKEHFF_02272 3.5e-143 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OFLKEHFF_02273 4e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OFLKEHFF_02274 3.4e-169 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OFLKEHFF_02275 7.7e-285 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OFLKEHFF_02276 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OFLKEHFF_02277 7.1e-231 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OFLKEHFF_02278 7.4e-27 yqzJ
OFLKEHFF_02279 3.6e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OFLKEHFF_02280 1.2e-200 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
OFLKEHFF_02281 8.8e-284 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OFLKEHFF_02282 3e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
OFLKEHFF_02284 3.3e-92 yqjB S protein conserved in bacteria
OFLKEHFF_02285 1.1e-167 yqjA S Putative aromatic acid exporter C-terminal domain
OFLKEHFF_02286 4.4e-124 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OFLKEHFF_02287 1.5e-102 artQ E COG0765 ABC-type amino acid transport system, permease component
OFLKEHFF_02288 1.4e-133 artP ET Belongs to the bacterial solute-binding protein 3 family
OFLKEHFF_02289 1e-75 yqiW S Belongs to the UPF0403 family
OFLKEHFF_02290 4.3e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OFLKEHFF_02291 4.5e-193 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OFLKEHFF_02292 1.1e-183 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OFLKEHFF_02293 3.3e-162 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OFLKEHFF_02294 2.6e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OFLKEHFF_02295 1.2e-205 buk 2.7.2.7 C Belongs to the acetokinase family
OFLKEHFF_02296 2.6e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
OFLKEHFF_02297 1.5e-150 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
OFLKEHFF_02298 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
OFLKEHFF_02299 2.7e-33 yqzF S Protein of unknown function (DUF2627)
OFLKEHFF_02300 3.8e-157 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OFLKEHFF_02301 9.5e-264 prpD 4.2.1.79 S 2-methylcitrate dehydratase
OFLKEHFF_02302 3.5e-205 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
OFLKEHFF_02303 1.5e-198 mmgC I acyl-CoA dehydrogenase
OFLKEHFF_02304 5.9e-144 hbdA 1.1.1.157 I Dehydrogenase
OFLKEHFF_02305 1.6e-208 mmgA 2.3.1.9 I Belongs to the thiolase family
OFLKEHFF_02306 4.3e-127 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OFLKEHFF_02307 2.3e-97 amiC 3.5.1.28 M Cell wall hydrolase autolysin
OFLKEHFF_02308 1.9e-17
OFLKEHFF_02309 1.7e-92 ytaF P Probably functions as a manganese efflux pump
OFLKEHFF_02310 3.2e-110 K Protein of unknown function (DUF1232)
OFLKEHFF_02312 4.6e-205 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OFLKEHFF_02315 1.1e-204 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OFLKEHFF_02317 1.6e-143 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OFLKEHFF_02318 5.4e-234 rseP 3.4.21.116 M Stage IV sporulation protein B
OFLKEHFF_02319 5.3e-309 recN L May be involved in recombinational repair of damaged DNA
OFLKEHFF_02320 4.3e-77 argR K Regulates arginine biosynthesis genes
OFLKEHFF_02321 2.6e-152 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
OFLKEHFF_02322 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OFLKEHFF_02323 7e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OFLKEHFF_02324 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OFLKEHFF_02325 2.5e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OFLKEHFF_02326 5.7e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OFLKEHFF_02327 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OFLKEHFF_02328 1.4e-66 yqhY S protein conserved in bacteria
OFLKEHFF_02329 5.9e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OFLKEHFF_02330 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OFLKEHFF_02331 3.4e-59 spoIIIAH S SpoIIIAH-like protein
OFLKEHFF_02332 3.9e-114 spoIIIAG S stage III sporulation protein AG
OFLKEHFF_02333 2.9e-100 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
OFLKEHFF_02334 2.6e-198 spoIIIAE S stage III sporulation protein AE
OFLKEHFF_02335 3.3e-41 spoIIIAD S Stage III sporulation protein AD
OFLKEHFF_02336 7.6e-29 spoIIIAC S stage III sporulation protein AC
OFLKEHFF_02337 1e-82 spoIIIAB S Stage III sporulation protein
OFLKEHFF_02338 2.9e-165 spoIIIAA S stage III sporulation protein AA
OFLKEHFF_02339 1.5e-35 yqhV S Protein of unknown function (DUF2619)
OFLKEHFF_02340 2.1e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OFLKEHFF_02341 7e-171 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OFLKEHFF_02342 7.8e-86 yqhR S Conserved membrane protein YqhR
OFLKEHFF_02343 2e-169 yqhQ S Protein of unknown function (DUF1385)
OFLKEHFF_02344 1.2e-59 yqhP
OFLKEHFF_02345 3.9e-159 yqhO S esterase of the alpha-beta hydrolase superfamily
OFLKEHFF_02346 6.1e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OFLKEHFF_02347 5.4e-158 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OFLKEHFF_02348 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
OFLKEHFF_02349 1.1e-283 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OFLKEHFF_02350 1.1e-248 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OFLKEHFF_02351 1.2e-200 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
OFLKEHFF_02352 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OFLKEHFF_02353 3.9e-150 yqhG S Bacterial protein YqhG of unknown function
OFLKEHFF_02354 1.7e-21 sinI S Anti-repressor SinI
OFLKEHFF_02355 3.9e-54 sinR K transcriptional
OFLKEHFF_02356 1.5e-138 tasA S Cell division protein FtsN
OFLKEHFF_02357 5.8e-66 sipW 3.4.21.89 U Signal peptidase
OFLKEHFF_02358 1.9e-113 yqxM
OFLKEHFF_02359 7e-53 yqzG S Protein of unknown function (DUF3889)
OFLKEHFF_02360 5.2e-26 yqzE S YqzE-like protein
OFLKEHFF_02361 2e-56 S ComG operon protein 7
OFLKEHFF_02362 8.1e-22 comGE
OFLKEHFF_02363 4.9e-70 gspH NU Tfp pilus assembly protein FimT
OFLKEHFF_02364 1.1e-40 comGC U Required for transformation and DNA binding
OFLKEHFF_02365 1.2e-178 comGB NU COG1459 Type II secretory pathway, component PulF
OFLKEHFF_02366 4e-198 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OFLKEHFF_02367 1.1e-09 corA P Mg2 transporter protein
OFLKEHFF_02368 7.4e-180 corA P Mg2 transporter protein
OFLKEHFF_02369 8.7e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OFLKEHFF_02370 1e-137 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OFLKEHFF_02372 2.5e-62 yqgZ 1.20.4.1 P Belongs to the ArsC family
OFLKEHFF_02373 3.1e-37 yqgY S Protein of unknown function (DUF2626)
OFLKEHFF_02374 6.2e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OFLKEHFF_02375 5.4e-20 yqgW S Protein of unknown function (DUF2759)
OFLKEHFF_02376 2.9e-48 yqgV S Thiamine-binding protein
OFLKEHFF_02377 1.9e-184 yqgU
OFLKEHFF_02378 2.7e-205 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
OFLKEHFF_02379 1.8e-178 glcK 2.7.1.2 G Glucokinase
OFLKEHFF_02380 1.6e-27 yqgQ S Protein conserved in bacteria
OFLKEHFF_02381 7e-210 nhaC C Na H antiporter
OFLKEHFF_02382 1.4e-07 yqgO
OFLKEHFF_02383 6.4e-91 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OFLKEHFF_02384 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OFLKEHFF_02385 1.2e-50 yqzD
OFLKEHFF_02386 6.6e-73 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OFLKEHFF_02387 6.4e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OFLKEHFF_02388 2.2e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OFLKEHFF_02389 2.9e-154 pstA P Phosphate transport system permease
OFLKEHFF_02390 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
OFLKEHFF_02391 2.1e-155 pstS P Phosphate
OFLKEHFF_02392 0.0 pbpA 3.4.16.4 M penicillin-binding protein
OFLKEHFF_02393 1.3e-222 yqgE EGP Major facilitator superfamily
OFLKEHFF_02394 5.3e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
OFLKEHFF_02395 4.2e-70 yqgC S protein conserved in bacteria
OFLKEHFF_02396 2.4e-128 yqgB S Protein of unknown function (DUF1189)
OFLKEHFF_02397 5.5e-44 yqfZ M LysM domain
OFLKEHFF_02398 5.9e-200 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OFLKEHFF_02399 1.5e-51 yqfX S membrane
OFLKEHFF_02400 6.7e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
OFLKEHFF_02401 2.4e-71 zur P Belongs to the Fur family
OFLKEHFF_02402 3.8e-154 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OFLKEHFF_02403 9.3e-37 yqfT S Protein of unknown function (DUF2624)
OFLKEHFF_02404 3.8e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OFLKEHFF_02405 3.6e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OFLKEHFF_02406 1.3e-32 yqfQ S YqfQ-like protein
OFLKEHFF_02407 1.6e-174 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OFLKEHFF_02408 1.8e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OFLKEHFF_02409 6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
OFLKEHFF_02410 1.3e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
OFLKEHFF_02411 3.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OFLKEHFF_02412 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OFLKEHFF_02413 8.7e-87 yaiI S Belongs to the UPF0178 family
OFLKEHFF_02414 1.4e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OFLKEHFF_02415 1.3e-111 ccpN K CBS domain
OFLKEHFF_02416 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OFLKEHFF_02417 3.7e-173 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OFLKEHFF_02418 6.1e-140 recO L Involved in DNA repair and RecF pathway recombination
OFLKEHFF_02419 1.8e-16 S YqzL-like protein
OFLKEHFF_02420 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OFLKEHFF_02421 1.2e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OFLKEHFF_02422 6.6e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OFLKEHFF_02423 9.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OFLKEHFF_02424 0.0 yqfF S membrane-associated HD superfamily hydrolase
OFLKEHFF_02425 9.5e-175 phoH T Phosphate starvation-inducible protein PhoH
OFLKEHFF_02426 1.9e-209 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
OFLKEHFF_02427 9.3e-46 yqfC S sporulation protein YqfC
OFLKEHFF_02428 6.5e-30 yqfB
OFLKEHFF_02429 5.3e-120 yqfA S UPF0365 protein
OFLKEHFF_02430 3.3e-226 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
OFLKEHFF_02431 1.2e-68 yqeY S Yqey-like protein
OFLKEHFF_02432 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OFLKEHFF_02433 9.9e-153 yqeW P COG1283 Na phosphate symporter
OFLKEHFF_02434 1.5e-258 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
OFLKEHFF_02435 3.7e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OFLKEHFF_02436 1.7e-173 prmA J Methylates ribosomal protein L11
OFLKEHFF_02437 6.1e-197 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OFLKEHFF_02438 0.0 dnaK O Heat shock 70 kDa protein
OFLKEHFF_02439 9.5e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OFLKEHFF_02440 1.4e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OFLKEHFF_02441 2.7e-208 hemN H Involved in the biosynthesis of porphyrin-containing compound
OFLKEHFF_02442 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OFLKEHFF_02443 9.4e-53 yqxA S Protein of unknown function (DUF3679)
OFLKEHFF_02444 4.6e-219 spoIIP M stage II sporulation protein P
OFLKEHFF_02445 5.6e-203 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OFLKEHFF_02446 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
OFLKEHFF_02447 3.3e-178 holA 2.7.7.7 L DNA polymerase III delta subunit
OFLKEHFF_02448 3.2e-15 S YqzM-like protein
OFLKEHFF_02449 0.0 comEC S Competence protein ComEC
OFLKEHFF_02450 2.6e-103 comEB 3.5.4.12 F ComE operon protein 2
OFLKEHFF_02451 9.9e-93 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
OFLKEHFF_02452 1.1e-142 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OFLKEHFF_02453 8.7e-136 yqeM Q Methyltransferase
OFLKEHFF_02454 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OFLKEHFF_02455 1.6e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OFLKEHFF_02456 3.4e-103 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OFLKEHFF_02457 1.5e-43 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
OFLKEHFF_02458 1.2e-152 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OFLKEHFF_02459 1.5e-211 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OFLKEHFF_02460 7.7e-94 yqeG S hydrolase of the HAD superfamily
OFLKEHFF_02462 1.5e-135 yqeF E GDSL-like Lipase/Acylhydrolase
OFLKEHFF_02463 1.6e-134 3.5.1.104 G Polysaccharide deacetylase
OFLKEHFF_02464 2.7e-108 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFLKEHFF_02465 1.4e-105 yqeD S SNARE associated Golgi protein
OFLKEHFF_02466 1.3e-15 2.3.1.57 K Acetyltransferase (GNAT) domain
OFLKEHFF_02467 2e-182 EGP Major facilitator Superfamily
OFLKEHFF_02468 9.9e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFLKEHFF_02469 6.4e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
OFLKEHFF_02470 8.7e-87 K Transcriptional regulator PadR-like family
OFLKEHFF_02471 2.4e-98 adk 2.7.4.3 F adenylate kinase activity
OFLKEHFF_02472 1.5e-31 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFLKEHFF_02473 3.8e-61 traX S TraX protein
OFLKEHFF_02474 3.8e-30 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OFLKEHFF_02475 9.9e-83 yrdA S DinB family
OFLKEHFF_02476 5.5e-139 S hydrolase
OFLKEHFF_02477 1.1e-137 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
OFLKEHFF_02478 6e-121 glvR K Helix-turn-helix domain, rpiR family
OFLKEHFF_02479 2.3e-173 manA 5.3.1.8 G mannose-6-phosphate isomerase
OFLKEHFF_02480 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
OFLKEHFF_02481 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
OFLKEHFF_02482 1.3e-168 romA S Beta-lactamase superfamily domain
OFLKEHFF_02483 5.6e-75 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OFLKEHFF_02484 2.8e-160 yybE K Transcriptional regulator
OFLKEHFF_02485 1.6e-208 ynfM EGP Major facilitator Superfamily
OFLKEHFF_02486 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OFLKEHFF_02487 1.4e-96 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
OFLKEHFF_02488 2.5e-87 yrhH Q methyltransferase
OFLKEHFF_02490 2.4e-139 focA P Formate nitrite
OFLKEHFF_02491 1.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
OFLKEHFF_02493 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OFLKEHFF_02494 3.2e-78 yrhD S Protein of unknown function (DUF1641)
OFLKEHFF_02495 1e-34 yrhC S YrhC-like protein
OFLKEHFF_02496 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OFLKEHFF_02497 3.8e-165 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
OFLKEHFF_02498 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OFLKEHFF_02499 2.8e-114 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
OFLKEHFF_02500 4.1e-27 yrzA S Protein of unknown function (DUF2536)
OFLKEHFF_02501 1.6e-65 yrrS S Protein of unknown function (DUF1510)
OFLKEHFF_02502 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
OFLKEHFF_02503 5.9e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OFLKEHFF_02504 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
OFLKEHFF_02505 2.8e-243 yegQ O COG0826 Collagenase and related proteases
OFLKEHFF_02506 4.3e-172 yegQ O Peptidase U32
OFLKEHFF_02507 1.4e-113 yrrM 2.1.1.104 S O-methyltransferase
OFLKEHFF_02508 2.6e-181 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OFLKEHFF_02509 7.1e-46 yrzB S Belongs to the UPF0473 family
OFLKEHFF_02510 3.6e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OFLKEHFF_02511 8.5e-41 yrzL S Belongs to the UPF0297 family
OFLKEHFF_02512 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OFLKEHFF_02513 2.2e-156 yrrI S AI-2E family transporter
OFLKEHFF_02514 1.2e-126 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OFLKEHFF_02515 4.4e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
OFLKEHFF_02516 8e-109 gluC P ABC transporter
OFLKEHFF_02517 4.1e-105 glnP P ABC transporter
OFLKEHFF_02518 2.1e-08 S Protein of unknown function (DUF3918)
OFLKEHFF_02519 2.9e-30 yrzR
OFLKEHFF_02520 3.9e-78 yrrD S protein conserved in bacteria
OFLKEHFF_02521 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OFLKEHFF_02522 1.7e-18 S COG0457 FOG TPR repeat
OFLKEHFF_02523 1.1e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OFLKEHFF_02524 2.9e-207 iscS 2.8.1.7 E Cysteine desulfurase
OFLKEHFF_02525 2.9e-63 cymR K Transcriptional regulator
OFLKEHFF_02526 7e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OFLKEHFF_02527 9.6e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OFLKEHFF_02528 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OFLKEHFF_02529 1.5e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
OFLKEHFF_02532 1.8e-268 lytH 3.5.1.28 M COG3103 SH3 domain protein
OFLKEHFF_02533 2e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OFLKEHFF_02534 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OFLKEHFF_02535 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OFLKEHFF_02536 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OFLKEHFF_02537 3.1e-45 yrvD S Lipopolysaccharide assembly protein A domain
OFLKEHFF_02538 1.7e-82 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
OFLKEHFF_02539 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OFLKEHFF_02540 1.1e-47 yrzD S Post-transcriptional regulator
OFLKEHFF_02541 3.1e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFLKEHFF_02542 5.6e-102 yrbG S membrane
OFLKEHFF_02543 5.3e-60 yrzE S Protein of unknown function (DUF3792)
OFLKEHFF_02544 2.5e-37 yajC U Preprotein translocase subunit YajC
OFLKEHFF_02545 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OFLKEHFF_02546 2e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OFLKEHFF_02547 1.3e-20 yrzS S Protein of unknown function (DUF2905)
OFLKEHFF_02548 6.4e-182 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OFLKEHFF_02549 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OFLKEHFF_02550 5.9e-91 bofC S BofC C-terminal domain
OFLKEHFF_02552 1e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OFLKEHFF_02553 1.4e-116 safA M spore coat assembly protein SafA
OFLKEHFF_02554 1.2e-208 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OFLKEHFF_02555 3.5e-141 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
OFLKEHFF_02556 7.9e-280 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
OFLKEHFF_02557 6.8e-212 nifS 2.8.1.7 E Cysteine desulfurase
OFLKEHFF_02558 2.6e-89 niaR S small molecule binding protein (contains 3H domain)
OFLKEHFF_02559 4.7e-157 pheA 4.2.1.51 E Prephenate dehydratase
OFLKEHFF_02560 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
OFLKEHFF_02561 2.2e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OFLKEHFF_02562 4.8e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
OFLKEHFF_02563 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OFLKEHFF_02564 7e-56 ysxB J ribosomal protein
OFLKEHFF_02565 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
OFLKEHFF_02566 1.4e-156 spoIVFB S Stage IV sporulation protein
OFLKEHFF_02567 1.1e-136 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
OFLKEHFF_02568 2.3e-142 minD D Belongs to the ParA family
OFLKEHFF_02569 9.3e-92 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OFLKEHFF_02570 9.6e-81 mreD M shape-determining protein
OFLKEHFF_02571 1.2e-157 mreC M Involved in formation and maintenance of cell shape
OFLKEHFF_02572 1.3e-182 mreB D Rod shape-determining protein MreB
OFLKEHFF_02573 3.5e-126 radC E Belongs to the UPF0758 family
OFLKEHFF_02574 3.3e-98 maf D septum formation protein Maf
OFLKEHFF_02575 3.2e-125 spoIIB S Sporulation related domain
OFLKEHFF_02576 5e-123 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OFLKEHFF_02577 3.3e-231 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OFLKEHFF_02578 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OFLKEHFF_02579 3.1e-24
OFLKEHFF_02580 7.5e-186 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OFLKEHFF_02581 8.1e-152 spoVID M stage VI sporulation protein D
OFLKEHFF_02582 1.6e-241 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OFLKEHFF_02583 2.5e-183 hemB 4.2.1.24 H Belongs to the ALAD family
OFLKEHFF_02584 2.4e-136 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OFLKEHFF_02585 4.6e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OFLKEHFF_02586 3.6e-146 hemX O cytochrome C
OFLKEHFF_02587 3.6e-244 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OFLKEHFF_02588 2.6e-83 ysxD
OFLKEHFF_02589 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
OFLKEHFF_02590 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OFLKEHFF_02591 3.9e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
OFLKEHFF_02592 1.9e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OFLKEHFF_02593 1.8e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OFLKEHFF_02594 3.3e-186 ysoA H Tetratricopeptide repeat
OFLKEHFF_02595 9e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OFLKEHFF_02596 9.4e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OFLKEHFF_02597 1.3e-196 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OFLKEHFF_02598 5.3e-284 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OFLKEHFF_02599 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OFLKEHFF_02600 3.5e-83 ilvN 2.2.1.6 E Acetolactate synthase
OFLKEHFF_02601 0.0 ilvB 2.2.1.6 E Acetolactate synthase
OFLKEHFF_02606 3.2e-89 ysnB S Phosphoesterase
OFLKEHFF_02607 8e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OFLKEHFF_02608 4.5e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OFLKEHFF_02609 3.4e-197 gerM S COG5401 Spore germination protein
OFLKEHFF_02610 9.6e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OFLKEHFF_02611 1.1e-72 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
OFLKEHFF_02612 2e-30 gerE K Transcriptional regulator
OFLKEHFF_02613 2.1e-73 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
OFLKEHFF_02614 3.9e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OFLKEHFF_02615 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OFLKEHFF_02616 4.8e-108 sdhC C succinate dehydrogenase
OFLKEHFF_02617 3.5e-79 yslB S Protein of unknown function (DUF2507)
OFLKEHFF_02618 2.8e-211 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OFLKEHFF_02619 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OFLKEHFF_02620 2.5e-52 trxA O Belongs to the thioredoxin family
OFLKEHFF_02621 1e-292 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
OFLKEHFF_02622 6.7e-176 etfA C Electron transfer flavoprotein
OFLKEHFF_02623 4.8e-137 etfB C Electron transfer flavoprotein
OFLKEHFF_02624 6.8e-131 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OFLKEHFF_02625 2.7e-103 fadR K Transcriptional regulator
OFLKEHFF_02626 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OFLKEHFF_02627 7.3e-113 ywbB S Protein of unknown function (DUF2711)
OFLKEHFF_02628 4.7e-67 yshE S membrane
OFLKEHFF_02629 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OFLKEHFF_02630 0.0 polX L COG1796 DNA polymerase IV (family X)
OFLKEHFF_02631 6.2e-83 cvpA S membrane protein, required for colicin V production
OFLKEHFF_02632 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OFLKEHFF_02633 1.8e-165 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OFLKEHFF_02634 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OFLKEHFF_02635 6.8e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OFLKEHFF_02636 1.6e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OFLKEHFF_02637 7.6e-32 sspI S Belongs to the SspI family
OFLKEHFF_02638 3.4e-189 ysfB KT regulator
OFLKEHFF_02639 8e-255 glcD 1.1.3.15 C FAD binding domain
OFLKEHFF_02640 8.9e-248 glcF C Glycolate oxidase
OFLKEHFF_02641 0.0 cstA T Carbon starvation protein
OFLKEHFF_02642 3.4e-296 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
OFLKEHFF_02643 5.1e-140 araQ G transport system permease
OFLKEHFF_02644 6.7e-165 araP P PFAM binding-protein-dependent transport systems inner membrane component
OFLKEHFF_02645 5.6e-247 araN G carbohydrate transport
OFLKEHFF_02646 3.3e-209 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
OFLKEHFF_02647 2e-136 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
OFLKEHFF_02648 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
OFLKEHFF_02649 3.7e-307 araB 2.7.1.16 C Belongs to the ribulokinase family
OFLKEHFF_02650 1.9e-291 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OFLKEHFF_02651 3e-184 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OFLKEHFF_02652 2e-205 ysdC G COG1363 Cellulase M and related proteins
OFLKEHFF_02653 2e-62 ysdB S Sigma-w pathway protein YsdB
OFLKEHFF_02654 5.5e-40 ysdA S Membrane
OFLKEHFF_02655 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OFLKEHFF_02656 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OFLKEHFF_02657 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OFLKEHFF_02658 2.7e-107 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OFLKEHFF_02659 3.2e-37 lrgA S effector of murein hydrolase LrgA
OFLKEHFF_02660 1e-128 lytT T COG3279 Response regulator of the LytR AlgR family
OFLKEHFF_02661 0.0 lytS 2.7.13.3 T Histidine kinase
OFLKEHFF_02662 3.4e-146 ysaA S HAD-hyrolase-like
OFLKEHFF_02663 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OFLKEHFF_02664 1.7e-148 ytxC S YtxC-like family
OFLKEHFF_02665 9e-105 ytxB S SNARE associated Golgi protein
OFLKEHFF_02666 2.9e-168 dnaI L Primosomal protein DnaI
OFLKEHFF_02667 9.1e-251 dnaB L Membrane attachment protein
OFLKEHFF_02668 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OFLKEHFF_02669 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OFLKEHFF_02670 1.3e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OFLKEHFF_02671 1.6e-64 ytcD K Transcriptional regulator
OFLKEHFF_02672 8.1e-200 ytbD EGP Major facilitator Superfamily
OFLKEHFF_02673 1.9e-155 ytbE S reductase
OFLKEHFF_02674 1.9e-93 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OFLKEHFF_02675 2.6e-104 ytaF P Probably functions as a manganese efflux pump
OFLKEHFF_02676 3.6e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OFLKEHFF_02677 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OFLKEHFF_02678 2.9e-310 phoR 2.7.13.3 T Signal transduction histidine kinase
OFLKEHFF_02679 1.7e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFLKEHFF_02680 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
OFLKEHFF_02681 7.7e-241 icd 1.1.1.42 C isocitrate
OFLKEHFF_02682 8.1e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
OFLKEHFF_02683 9.1e-73 yeaL S membrane
OFLKEHFF_02684 3.1e-193 ytvI S sporulation integral membrane protein YtvI
OFLKEHFF_02685 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
OFLKEHFF_02686 5.4e-293 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OFLKEHFF_02687 4.8e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OFLKEHFF_02688 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OFLKEHFF_02689 7.8e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OFLKEHFF_02690 1.2e-222 ytsJ 1.1.1.38 C Malate dehydrogenase
OFLKEHFF_02691 0.0 dnaE 2.7.7.7 L DNA polymerase
OFLKEHFF_02692 7.8e-55 ytrH S Sporulation protein YtrH
OFLKEHFF_02693 1.9e-86 ytrI
OFLKEHFF_02694 3.7e-22
OFLKEHFF_02695 1.4e-175 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
OFLKEHFF_02696 1.5e-46 ytpI S YtpI-like protein
OFLKEHFF_02697 6.3e-238 ytoI K transcriptional regulator containing CBS domains
OFLKEHFF_02698 4.8e-128 ytkL S Belongs to the UPF0173 family
OFLKEHFF_02699 6.1e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFLKEHFF_02701 1e-259 argH 4.3.2.1 E argininosuccinate lyase
OFLKEHFF_02702 4.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OFLKEHFF_02703 8e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
OFLKEHFF_02704 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OFLKEHFF_02705 1.5e-175 ytxK 2.1.1.72 L DNA methylase
OFLKEHFF_02706 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OFLKEHFF_02707 1.5e-63 ytfJ S Sporulation protein YtfJ
OFLKEHFF_02708 2.4e-111 ytfI S Protein of unknown function (DUF2953)
OFLKEHFF_02709 4.4e-83 yteJ S RDD family
OFLKEHFF_02710 1.1e-176 sppA OU signal peptide peptidase SppA
OFLKEHFF_02711 5.9e-149 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OFLKEHFF_02712 1.7e-298 ytcJ S amidohydrolase
OFLKEHFF_02713 9.1e-300 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OFLKEHFF_02714 3.9e-31 sspB S spore protein
OFLKEHFF_02715 2.4e-220 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OFLKEHFF_02716 1.2e-203 iscS2 2.8.1.7 E Cysteine desulfurase
OFLKEHFF_02717 3.8e-238 braB E Component of the transport system for branched-chain amino acids
OFLKEHFF_02718 7.6e-260 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OFLKEHFF_02719 8.6e-145 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
OFLKEHFF_02720 4.2e-107 yttP K Transcriptional regulator
OFLKEHFF_02721 2.3e-84 ytsP 1.8.4.14 T GAF domain-containing protein
OFLKEHFF_02722 9.5e-266 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
OFLKEHFF_02723 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OFLKEHFF_02724 1.2e-214 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OFLKEHFF_02725 1e-10
OFLKEHFF_02728 6.4e-126 E GDSL-like Lipase/Acylhydrolase family
OFLKEHFF_02729 7.6e-147 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OFLKEHFF_02730 8.3e-148 K Transcriptional regulator
OFLKEHFF_02731 3e-120 azlC E AzlC protein
OFLKEHFF_02732 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
OFLKEHFF_02733 5.7e-236 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OFLKEHFF_02734 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OFLKEHFF_02735 1.3e-119 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OFLKEHFF_02736 3.8e-111 acuB S Domain in cystathionine beta-synthase and other proteins.
OFLKEHFF_02737 1.8e-223 acuC BQ histone deacetylase
OFLKEHFF_02738 2.8e-112 motS N Flagellar motor protein
OFLKEHFF_02739 2.1e-143 motA N flagellar motor
OFLKEHFF_02740 2.1e-177 ccpA K catabolite control protein A
OFLKEHFF_02741 3.5e-194 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OFLKEHFF_02742 2.9e-43 ytxJ O Protein of unknown function (DUF2847)
OFLKEHFF_02743 1.7e-16 ytxH S COG4980 Gas vesicle protein
OFLKEHFF_02744 1.1e-13 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OFLKEHFF_02745 6e-249 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OFLKEHFF_02746 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OFLKEHFF_02747 1.2e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OFLKEHFF_02748 1.7e-145 ytpQ S Belongs to the UPF0354 family
OFLKEHFF_02749 5.1e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OFLKEHFF_02750 1.8e-75 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
OFLKEHFF_02751 1.4e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
OFLKEHFF_02752 1.7e-51 ytzB S small secreted protein
OFLKEHFF_02753 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
OFLKEHFF_02754 9e-161 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
OFLKEHFF_02755 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OFLKEHFF_02756 1.3e-44 ytzH S YtzH-like protein
OFLKEHFF_02757 4.1e-155 ytmP 2.7.1.89 M Phosphotransferase
OFLKEHFF_02758 4.4e-169 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
OFLKEHFF_02759 4.3e-140 ytlQ
OFLKEHFF_02760 8.3e-99 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OFLKEHFF_02761 2.7e-166 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OFLKEHFF_02762 1.2e-258 pepV 3.5.1.18 E Dipeptidase
OFLKEHFF_02763 5.5e-226 pbuO S permease
OFLKEHFF_02764 2.3e-199 ythQ U Bacterial ABC transporter protein EcsB
OFLKEHFF_02765 1.5e-116 ythP V ABC transporter
OFLKEHFF_02766 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
OFLKEHFF_02767 1.4e-125 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OFLKEHFF_02768 9.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFLKEHFF_02769 1.2e-230 ytfP S HI0933-like protein
OFLKEHFF_02770 4e-276 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
OFLKEHFF_02771 2.6e-25 yteV S Sporulation protein Cse60
OFLKEHFF_02772 4e-179 msmR K Transcriptional regulator
OFLKEHFF_02773 4.9e-235 msmE G Bacterial extracellular solute-binding protein
OFLKEHFF_02774 1.2e-163 amyD G Binding-protein-dependent transport system inner membrane component
OFLKEHFF_02775 1.2e-141 amyC P ABC transporter (permease)
OFLKEHFF_02776 8.1e-246 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OFLKEHFF_02777 5.9e-72 M Acetyltransferase (GNAT) domain
OFLKEHFF_02778 4.8e-51 ytwF P Sulfurtransferase
OFLKEHFF_02779 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OFLKEHFF_02780 1.2e-52 ytvB S Protein of unknown function (DUF4257)
OFLKEHFF_02781 1.6e-135 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
OFLKEHFF_02782 2.4e-204 yttB EGP Major facilitator Superfamily
OFLKEHFF_02783 3.6e-118 ywaF S Integral membrane protein
OFLKEHFF_02784 0.0 bceB V ABC transporter (permease)
OFLKEHFF_02785 1.6e-132 bceA V ABC transporter, ATP-binding protein
OFLKEHFF_02786 1.5e-156 T PhoQ Sensor
OFLKEHFF_02787 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFLKEHFF_02788 4e-200 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
OFLKEHFF_02789 2.5e-124 ytrE V ABC transporter, ATP-binding protein
OFLKEHFF_02790 1.5e-146
OFLKEHFF_02791 5.5e-146 P ABC-2 family transporter protein
OFLKEHFF_02792 4.7e-161 S ABC-2 family transporter protein
OFLKEHFF_02793 1.4e-156 ytrB P abc transporter atp-binding protein
OFLKEHFF_02794 4.3e-65 ytrA K GntR family transcriptional regulator
OFLKEHFF_02796 2.8e-39 ytzC S Protein of unknown function (DUF2524)
OFLKEHFF_02797 5.2e-189 yhcC S Fe-S oxidoreductase
OFLKEHFF_02798 1.7e-102 ytqB J Putative rRNA methylase
OFLKEHFF_02800 3.5e-130 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
OFLKEHFF_02801 7.3e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
OFLKEHFF_02802 7.2e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
OFLKEHFF_02803 1.8e-55 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OFLKEHFF_02804 1.3e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
OFLKEHFF_02805 0.0 asnB 6.3.5.4 E Asparagine synthase
OFLKEHFF_02806 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OFLKEHFF_02807 4e-303 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OFLKEHFF_02808 1.6e-38 ytmB S Protein of unknown function (DUF2584)
OFLKEHFF_02809 1.4e-144 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OFLKEHFF_02810 5.6e-178 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OFLKEHFF_02811 1.5e-141 ytlC P ABC transporter
OFLKEHFF_02812 3.8e-124 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OFLKEHFF_02813 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
OFLKEHFF_02814 9.5e-60 ytkC S Bacteriophage holin family
OFLKEHFF_02815 7.8e-76 dps P Belongs to the Dps family
OFLKEHFF_02817 6.7e-75 ytkA S YtkA-like
OFLKEHFF_02818 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OFLKEHFF_02819 1.2e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
OFLKEHFF_02820 6.3e-102 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OFLKEHFF_02821 7.9e-41 rpmE2 J Ribosomal protein L31
OFLKEHFF_02822 1.5e-239 cydA 1.10.3.14 C oxidase, subunit
OFLKEHFF_02823 7.1e-184 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
OFLKEHFF_02824 1.3e-23 S Domain of Unknown Function (DUF1540)
OFLKEHFF_02825 2.6e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OFLKEHFF_02826 7.2e-267 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OFLKEHFF_02827 1.3e-153 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OFLKEHFF_02828 1.3e-148 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OFLKEHFF_02829 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OFLKEHFF_02830 7.7e-258 menF 5.4.4.2 HQ Isochorismate synthase
OFLKEHFF_02831 3.9e-125 dksA T COG1734 DnaK suppressor protein
OFLKEHFF_02832 2.8e-71 tspO T membrane
OFLKEHFF_02841 7.8e-08
OFLKEHFF_02842 1.3e-09
OFLKEHFF_02849 1.6e-08
OFLKEHFF_02854 2.2e-38 S COG NOG14552 non supervised orthologous group
OFLKEHFF_02855 2.7e-92 thiT S Thiamine transporter protein (Thia_YuaJ)
OFLKEHFF_02856 6.8e-175 yuaG 3.4.21.72 S protein conserved in bacteria
OFLKEHFF_02857 5.8e-81 yuaF OU Membrane protein implicated in regulation of membrane protease activity
OFLKEHFF_02858 6.5e-79 yuaE S DinB superfamily
OFLKEHFF_02859 1e-102 yuaD S MOSC domain
OFLKEHFF_02860 8.7e-226 gbsB 1.1.1.1 C alcohol dehydrogenase
OFLKEHFF_02861 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
OFLKEHFF_02862 3.4e-92 yuaC K Belongs to the GbsR family
OFLKEHFF_02863 9.6e-92 yuaB
OFLKEHFF_02864 1.4e-119 ktrA P COG0569 K transport systems, NAD-binding component
OFLKEHFF_02865 4.2e-142 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OFLKEHFF_02866 2.5e-209 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OFLKEHFF_02867 4.5e-112 G Cupin
OFLKEHFF_02868 1.3e-43 yjcN
OFLKEHFF_02869 2.5e-99 K Helix-turn-helix domain
OFLKEHFF_02871 3.8e-14 S YolD-like protein
OFLKEHFF_02873 1.7e-33 S Bacteriophage A118-like holin, Hol118
OFLKEHFF_02874 6.5e-144 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
OFLKEHFF_02875 5.9e-29 S BhlA holin family
OFLKEHFF_02877 3.3e-14
OFLKEHFF_02878 2.6e-81
OFLKEHFF_02879 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
OFLKEHFF_02880 2.9e-79 L Prophage endopeptidase tail
OFLKEHFF_02881 5.5e-62 S Phage tail protein
OFLKEHFF_02882 1e-160 D phage tail tape measure protein
OFLKEHFF_02884 2.2e-23
OFLKEHFF_02885 7.9e-49 eae N domain, Protein
OFLKEHFF_02886 3.2e-20
OFLKEHFF_02887 1.3e-29
OFLKEHFF_02888 2.6e-10
OFLKEHFF_02889 1.2e-27
OFLKEHFF_02892 2.7e-149 S Family of unknown function (DUF5309)
OFLKEHFF_02893 1.5e-17
OFLKEHFF_02894 3.8e-79 S Phage minor capsid protein 2
OFLKEHFF_02895 6.8e-165
OFLKEHFF_02896 9.3e-29 S Helix-turn-helix of insertion element transposase
OFLKEHFF_02897 1.4e-256 S TIGRFAM Phage
OFLKEHFF_02898 2.2e-67 L Phage integrase family
OFLKEHFF_02901 8.3e-44 epsH GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
OFLKEHFF_02902 1.1e-28 K Cro/C1-type HTH DNA-binding domain
OFLKEHFF_02903 9.3e-59 S Pfam:DUF867
OFLKEHFF_02904 8.8e-118 3.2.1.15 M Right handed beta helix region
OFLKEHFF_02907 1.7e-59 S Protein of unknown function (DUF2786)
OFLKEHFF_02909 9.2e-23
OFLKEHFF_02911 2.1e-119 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
OFLKEHFF_02913 2.7e-135
OFLKEHFF_02914 9.2e-50
OFLKEHFF_02915 1.4e-47 K Sigma-70, region 4
OFLKEHFF_02917 5.8e-66 2.7.1.24 H dephospho-CoA kinase activity
OFLKEHFF_02918 1.2e-36
OFLKEHFF_02919 6.7e-51 O peptidyl-tyrosine sulfation
OFLKEHFF_02920 7.7e-36 S protein conserved in bacteria
OFLKEHFF_02921 1.7e-111 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OFLKEHFF_02923 3.2e-58 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
OFLKEHFF_02925 2e-148 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFLKEHFF_02927 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OFLKEHFF_02928 2e-62 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
OFLKEHFF_02929 6e-42 nrdI 1.17.4.1 F Belongs to the NrdI family
OFLKEHFF_02933 6.4e-15 S Protein of unknown function (DUF1523)
OFLKEHFF_02934 2.9e-32 3.1.22.4 S Crossover junction endodeoxyribonuclease RuvC
OFLKEHFF_02936 1.2e-162
OFLKEHFF_02937 1.9e-103 2.7.7.7 L EXOIII
OFLKEHFF_02938 1e-77 S RNA ligase
OFLKEHFF_02939 1.9e-202 L 3'-5' exonuclease
OFLKEHFF_02941 4.3e-29
OFLKEHFF_02943 4.3e-50
OFLKEHFF_02944 1.5e-95
OFLKEHFF_02949 1.6e-43
OFLKEHFF_02950 2.7e-08 S Cro/C1-type HTH DNA-binding domain
OFLKEHFF_02951 2.7e-132 dnaG L Toprim-like
OFLKEHFF_02952 9e-142 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
OFLKEHFF_02954 2.1e-11 yodN
OFLKEHFF_02955 4.3e-109 L DNA-dependent DNA replication
OFLKEHFF_02957 6.3e-56
OFLKEHFF_02959 1.2e-16
OFLKEHFF_02964 1e-35
OFLKEHFF_02966 2.1e-08 S Helix-turn-helix domain
OFLKEHFF_02967 6.7e-89 L Belongs to the 'phage' integrase family
OFLKEHFF_02969 2.8e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OFLKEHFF_02970 5.5e-193 yubA S transporter activity
OFLKEHFF_02971 2e-180 ygjR S Oxidoreductase
OFLKEHFF_02972 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
OFLKEHFF_02973 1.2e-227 mcpA NT chemotaxis protein
OFLKEHFF_02974 1.8e-220 mcpA NT chemotaxis protein
OFLKEHFF_02975 2.5e-214 mcpA NT chemotaxis protein
OFLKEHFF_02976 2.7e-208 mcpA NT chemotaxis protein
OFLKEHFF_02977 8.7e-136 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
OFLKEHFF_02978 7.6e-39
OFLKEHFF_02979 1.5e-186 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OFLKEHFF_02980 1.6e-73 yugU S Uncharacterised protein family UPF0047
OFLKEHFF_02981 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
OFLKEHFF_02982 8.1e-230 yugS S COG1253 Hemolysins and related proteins containing CBS domains
OFLKEHFF_02983 8.3e-117 yugP S Zn-dependent protease
OFLKEHFF_02984 2.9e-17
OFLKEHFF_02985 1.8e-27 mstX S Membrane-integrating protein Mistic
OFLKEHFF_02986 3e-176 yugO P COG1226 Kef-type K transport systems
OFLKEHFF_02987 1.1e-68 yugN S YugN-like family
OFLKEHFF_02989 2.1e-257 pgi 5.3.1.9 G Belongs to the GPI family
OFLKEHFF_02990 2.2e-14 S NADPH-dependent FMN reductase
OFLKEHFF_02991 9.5e-63 S NADPH-dependent FMN reductase
OFLKEHFF_02992 2.7e-117 ycaC Q Isochorismatase family
OFLKEHFF_02993 1.7e-226 yugK C Dehydrogenase
OFLKEHFF_02994 7.8e-224 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
OFLKEHFF_02995 6.8e-34 yuzA S Domain of unknown function (DUF378)
OFLKEHFF_02996 6.4e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
OFLKEHFF_02997 7.4e-206 yugH 2.6.1.1 E Aminotransferase
OFLKEHFF_02998 5.8e-83 alaR K Transcriptional regulator
OFLKEHFF_02999 3.8e-148 yugF I Hydrolase
OFLKEHFF_03000 5e-38 yugE S Domain of unknown function (DUF1871)
OFLKEHFF_03001 6.4e-218 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OFLKEHFF_03002 5.2e-221 T PhoQ Sensor
OFLKEHFF_03003 1.1e-62 kapB G Kinase associated protein B
OFLKEHFF_03004 4.2e-116 kapD L the KinA pathway to sporulation
OFLKEHFF_03005 2.6e-165 yuxJ EGP Major facilitator Superfamily
OFLKEHFF_03006 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
OFLKEHFF_03007 1e-69 yuxK S protein conserved in bacteria
OFLKEHFF_03008 1.1e-71 yufK S Family of unknown function (DUF5366)
OFLKEHFF_03009 1.3e-290 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OFLKEHFF_03010 1.1e-124 dcuR T COG4565 Response regulator of citrate malate metabolism
OFLKEHFF_03011 3e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OFLKEHFF_03012 5.4e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OFLKEHFF_03013 1.3e-180 yufP S Belongs to the binding-protein-dependent transport system permease family
OFLKEHFF_03014 2.7e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
OFLKEHFF_03015 7.5e-11
OFLKEHFF_03016 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OFLKEHFF_03017 2.7e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OFLKEHFF_03018 2.2e-49 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OFLKEHFF_03019 7.4e-259 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OFLKEHFF_03020 6.1e-74 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OFLKEHFF_03021 2.1e-37 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OFLKEHFF_03022 8.2e-58 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
OFLKEHFF_03023 4.5e-59 ydiI Q protein, possibly involved in aromatic compounds catabolism
OFLKEHFF_03024 6.9e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFLKEHFF_03025 9.7e-236 comP 2.7.13.3 T Histidine kinase
OFLKEHFF_03027 2e-70 comQ H Polyprenyl synthetase
OFLKEHFF_03029 6e-47 yuzC
OFLKEHFF_03030 2e-222 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
OFLKEHFF_03031 3.7e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OFLKEHFF_03032 8.9e-101 pncA Q COG1335 Amidases related to nicotinamidase
OFLKEHFF_03033 1.1e-65 yueI S Protein of unknown function (DUF1694)
OFLKEHFF_03034 4.8e-38 yueH S YueH-like protein
OFLKEHFF_03035 7.1e-33 yueG S Spore germination protein gerPA/gerPF
OFLKEHFF_03036 3.9e-180 yueF S transporter activity
OFLKEHFF_03037 1.6e-22 S Protein of unknown function (DUF2642)
OFLKEHFF_03038 7e-95 yueE S phosphohydrolase
OFLKEHFF_03039 6.2e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFLKEHFF_03040 3.6e-74 yueC S Family of unknown function (DUF5383)
OFLKEHFF_03041 0.0 esaA S type VII secretion protein EsaA
OFLKEHFF_03042 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OFLKEHFF_03043 3.1e-197 essB S WXG100 protein secretion system (Wss), protein YukC
OFLKEHFF_03044 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
OFLKEHFF_03045 1.7e-45 esxA S Belongs to the WXG100 family
OFLKEHFF_03046 1.2e-225 yukF QT Transcriptional regulator
OFLKEHFF_03047 2e-203 ald 1.4.1.1 E Belongs to the AlaDH PNT family
OFLKEHFF_03048 1.5e-129 yukJ S Uncharacterized conserved protein (DUF2278)
OFLKEHFF_03049 8.4e-31 mbtH S MbtH-like protein
OFLKEHFF_03050 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFLKEHFF_03051 2.9e-165 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
OFLKEHFF_03052 1.4e-306 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
OFLKEHFF_03053 1.8e-215 entC 5.4.4.2 HQ Isochorismate synthase
OFLKEHFF_03054 2.2e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFLKEHFF_03055 1.1e-153 besA S Putative esterase
OFLKEHFF_03056 5.6e-117 yuiH S Oxidoreductase molybdopterin binding domain
OFLKEHFF_03057 6.2e-100 bioY S Biotin biosynthesis protein
OFLKEHFF_03058 1.5e-207 yuiF S antiporter
OFLKEHFF_03059 7.1e-278 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OFLKEHFF_03060 3.8e-76 yuiD S protein conserved in bacteria
OFLKEHFF_03061 9.6e-115 yuiC S protein conserved in bacteria
OFLKEHFF_03062 4.9e-27 yuiB S Putative membrane protein
OFLKEHFF_03063 1.1e-233 yumB 1.6.99.3 C NADH dehydrogenase
OFLKEHFF_03064 1.8e-184 yumC 1.18.1.2, 1.19.1.1 C reductase
OFLKEHFF_03066 1.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OFLKEHFF_03067 4.8e-129 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
OFLKEHFF_03068 2.6e-61 erpA S Belongs to the HesB IscA family
OFLKEHFF_03069 5.9e-160 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OFLKEHFF_03070 4.7e-203 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OFLKEHFF_03071 1.7e-37 yuzB S Belongs to the UPF0349 family
OFLKEHFF_03072 1.3e-204 yutJ 1.6.99.3 C NADH dehydrogenase
OFLKEHFF_03073 9.1e-53 yuzD S protein conserved in bacteria
OFLKEHFF_03074 1.6e-35 yutI O COG0694 Thioredoxin-like proteins and domains
OFLKEHFF_03075 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
OFLKEHFF_03076 7.5e-161 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OFLKEHFF_03077 4.5e-194 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OFLKEHFF_03078 1.9e-239 hom 1.1.1.3 E homoserine dehydrogenase
OFLKEHFF_03079 3.7e-193 yutH S Spore coat protein
OFLKEHFF_03080 2.6e-83 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OFLKEHFF_03081 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OFLKEHFF_03082 8.9e-72 yutE S Protein of unknown function DUF86
OFLKEHFF_03083 1.7e-47 yutD S protein conserved in bacteria
OFLKEHFF_03084 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OFLKEHFF_03085 3.3e-191 lytH M Peptidase, M23
OFLKEHFF_03086 1.1e-128 yunB S Sporulation protein YunB (Spo_YunB)
OFLKEHFF_03087 5.3e-259 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OFLKEHFF_03088 1.1e-142 yunE S membrane transporter protein
OFLKEHFF_03089 6.4e-167 yunF S Protein of unknown function DUF72
OFLKEHFF_03090 1.6e-55 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
OFLKEHFF_03091 4e-251 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
OFLKEHFF_03092 1.9e-292 pucR QT COG2508 Regulator of polyketide synthase expression
OFLKEHFF_03095 1.1e-65
OFLKEHFF_03096 1.4e-207 blt EGP Major facilitator Superfamily
OFLKEHFF_03097 2.5e-228 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OFLKEHFF_03098 6.4e-224 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OFLKEHFF_03099 3.7e-162 bsn L Ribonuclease
OFLKEHFF_03100 6.6e-196 msmX P Belongs to the ABC transporter superfamily
OFLKEHFF_03101 2e-132 yurK K UTRA
OFLKEHFF_03102 3.6e-157 yurL 2.7.1.218 G pfkB family carbohydrate kinase
OFLKEHFF_03103 6.3e-157 yurM P COG0395 ABC-type sugar transport system, permease component
OFLKEHFF_03104 2.2e-157 yurN G Binding-protein-dependent transport system inner membrane component
OFLKEHFF_03105 1e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
OFLKEHFF_03106 1.1e-181 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
OFLKEHFF_03107 1.9e-159 K helix_turn_helix, mercury resistance
OFLKEHFF_03108 1.8e-14
OFLKEHFF_03109 4e-77
OFLKEHFF_03110 9.3e-23 S Sporulation delaying protein SdpA
OFLKEHFF_03112 1.2e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
OFLKEHFF_03113 4.2e-198 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
OFLKEHFF_03114 4.6e-118 Q ubiE/COQ5 methyltransferase family
OFLKEHFF_03115 4.2e-72 yncE S Protein of unknown function (DUF2691)
OFLKEHFF_03116 2.7e-149 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
OFLKEHFF_03117 1.4e-295 hsdM 2.1.1.72 V Type I restriction-modification system
OFLKEHFF_03118 3.5e-102 3.1.21.3 V Type I restriction modification DNA specificity domain
OFLKEHFF_03119 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
OFLKEHFF_03120 1.7e-78 3.1.21.3 V Type I restriction modification DNA specificity domain
OFLKEHFF_03123 8.7e-270 sufB O FeS cluster assembly
OFLKEHFF_03124 7.9e-76 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
OFLKEHFF_03125 2.5e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OFLKEHFF_03126 7e-245 sufD O assembly protein SufD
OFLKEHFF_03127 6.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OFLKEHFF_03128 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OFLKEHFF_03129 1.2e-141 metQ P Belongs to the NlpA lipoprotein family
OFLKEHFF_03130 6.3e-93 metI P COG2011 ABC-type metal ion transport system, permease component
OFLKEHFF_03131 9.1e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OFLKEHFF_03132 2.1e-55 yusD S SCP-2 sterol transfer family
OFLKEHFF_03133 5.2e-53 yusE CO Thioredoxin
OFLKEHFF_03134 1.3e-60 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
OFLKEHFF_03135 2.1e-38 yusG S Protein of unknown function (DUF2553)
OFLKEHFF_03136 5.5e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OFLKEHFF_03137 1.8e-62 arsC 1.20.4.1 P Belongs to the ArsC family
OFLKEHFF_03138 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
OFLKEHFF_03139 3.9e-215 fadA 2.3.1.16 I Belongs to the thiolase family
OFLKEHFF_03140 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
OFLKEHFF_03142 1.2e-158 fadM E Proline dehydrogenase
OFLKEHFF_03143 1.2e-211 yusP P Major facilitator superfamily
OFLKEHFF_03144 4.1e-40
OFLKEHFF_03145 3.5e-52 yusN M Coat F domain
OFLKEHFF_03146 1.3e-71 yusO K Iron dependent repressor, N-terminal DNA binding domain
OFLKEHFF_03147 1.1e-284 yusP P Major facilitator superfamily
OFLKEHFF_03148 8.1e-38 yusU S Protein of unknown function (DUF2573)
OFLKEHFF_03149 3.1e-150 yusV 3.6.3.34 HP ABC transporter
OFLKEHFF_03150 2.9e-46 S YusW-like protein
OFLKEHFF_03151 0.0 pepF2 E COG1164 Oligoendopeptidase F
OFLKEHFF_03152 2.1e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFLKEHFF_03153 2.6e-77 dps P Belongs to the Dps family
OFLKEHFF_03154 9.1e-232 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OFLKEHFF_03155 3.1e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFLKEHFF_03156 1.1e-248 cssS 2.7.13.3 T PhoQ Sensor
OFLKEHFF_03157 1.3e-23
OFLKEHFF_03158 2.6e-153 yuxN K Transcriptional regulator
OFLKEHFF_03159 3.6e-260 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OFLKEHFF_03160 6.6e-24 S Protein of unknown function (DUF3970)
OFLKEHFF_03161 3.1e-254 gerAA EG Spore germination protein
OFLKEHFF_03162 5.6e-179 gerAB E Spore germination protein
OFLKEHFF_03163 1.7e-188 gerAC S Spore germination B3/ GerAC like, C-terminal
OFLKEHFF_03164 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFLKEHFF_03165 2.3e-193 vraS 2.7.13.3 T Histidine kinase
OFLKEHFF_03166 8.4e-123 yvqF S Cell wall-active antibiotics response 4TMS YvqF
OFLKEHFF_03167 1.8e-119 liaG S Putative adhesin
OFLKEHFF_03168 3.1e-87 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
OFLKEHFF_03169 3.4e-43 liaI S membrane
OFLKEHFF_03170 2e-220 yvqJ EGP Major facilitator Superfamily
OFLKEHFF_03171 4e-96 yvqK 2.5.1.17 S Adenosyltransferase
OFLKEHFF_03172 1.8e-202 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
OFLKEHFF_03173 1.9e-176 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFLKEHFF_03174 2.3e-165 yvrC P ABC transporter substrate-binding protein
OFLKEHFF_03175 5.8e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFLKEHFF_03176 1.9e-166 yvrE G SMP-30/Gluconolaconase/LRE-like region
OFLKEHFF_03177 0.0 T PhoQ Sensor
OFLKEHFF_03178 2e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFLKEHFF_03179 6.2e-35
OFLKEHFF_03180 5.5e-101 yvrI K RNA polymerase
OFLKEHFF_03181 1.6e-15 S YvrJ protein family
OFLKEHFF_03182 3.9e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
OFLKEHFF_03183 1.3e-59 yvrL S Regulatory protein YrvL
OFLKEHFF_03184 1.2e-146 fhuC 3.6.3.34 HP ABC transporter
OFLKEHFF_03185 1.3e-169 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFLKEHFF_03186 1.5e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFLKEHFF_03187 5.8e-177 fhuD P ABC transporter
OFLKEHFF_03188 1e-122 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OFLKEHFF_03189 3e-233 yvsH E Arginine ornithine antiporter
OFLKEHFF_03190 5.2e-13 S Small spore protein J (Spore_SspJ)
OFLKEHFF_03191 3.9e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
OFLKEHFF_03192 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OFLKEHFF_03193 6.4e-160 yvgK P COG1910 Periplasmic molybdate-binding protein domain
OFLKEHFF_03194 7.2e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
OFLKEHFF_03195 2.7e-90 modB P COG4149 ABC-type molybdate transport system, permease component
OFLKEHFF_03196 1.2e-112 yfiK K Regulator
OFLKEHFF_03197 3.4e-168 T Histidine kinase
OFLKEHFF_03198 1.4e-170 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
OFLKEHFF_03199 5.2e-185 yfiM V ABC-2 type transporter
OFLKEHFF_03200 1e-183 yfiN V COG0842 ABC-type multidrug transport system, permease component
OFLKEHFF_03201 1.2e-152 yvgN S reductase
OFLKEHFF_03202 6.6e-84 yvgO
OFLKEHFF_03203 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
OFLKEHFF_03204 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OFLKEHFF_03205 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OFLKEHFF_03206 0.0 helD 3.6.4.12 L DNA helicase
OFLKEHFF_03207 7e-99 yvgT S membrane
OFLKEHFF_03208 5.9e-138 S Metallo-peptidase family M12
OFLKEHFF_03209 6.6e-72 bdbC O Required for disulfide bond formation in some proteins
OFLKEHFF_03210 1.3e-98 bdbD O Thioredoxin
OFLKEHFF_03211 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OFLKEHFF_03212 0.0 copA 3.6.3.54 P P-type ATPase
OFLKEHFF_03213 1.4e-27 copZ P Heavy-metal-associated domain
OFLKEHFF_03214 7.6e-46 csoR S transcriptional
OFLKEHFF_03215 1.2e-186 yvaA 1.1.1.371 S Oxidoreductase
OFLKEHFF_03216 4.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OFLKEHFF_03217 2.6e-247 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFLKEHFF_03218 3.7e-42 ytnI O COG0695 Glutaredoxin and related proteins
OFLKEHFF_03219 1.3e-171 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFLKEHFF_03220 4e-139 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OFLKEHFF_03221 1.1e-116 tcyM U Binding-protein-dependent transport system inner membrane component
OFLKEHFF_03222 1.8e-117 tcyL P Binding-protein-dependent transport system inner membrane component
OFLKEHFF_03223 1.4e-142 tcyK M Bacterial periplasmic substrate-binding proteins
OFLKEHFF_03224 2.4e-126 ytmJ ET Bacterial periplasmic substrate-binding proteins
OFLKEHFF_03225 9e-98 ytmI K Acetyltransferase (GNAT) domain
OFLKEHFF_03226 1e-159 ytlI K LysR substrate binding domain
OFLKEHFF_03227 2.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OFLKEHFF_03228 1.5e-44 yrdF K ribonuclease inhibitor
OFLKEHFF_03229 1.6e-56
OFLKEHFF_03232 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OFLKEHFF_03233 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OFLKEHFF_03234 1.6e-142 est 3.1.1.1 S Carboxylesterase
OFLKEHFF_03235 4.2e-20 secG U Preprotein translocase subunit SecG
OFLKEHFF_03236 6e-35 yvzC K Transcriptional
OFLKEHFF_03237 1.6e-67 K transcriptional
OFLKEHFF_03238 9.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
OFLKEHFF_03239 1.4e-50 yodB K transcriptional
OFLKEHFF_03240 1.8e-238 T His Kinase A (phosphoacceptor) domain
OFLKEHFF_03241 1.3e-119 K Transcriptional regulatory protein, C terminal
OFLKEHFF_03242 1e-126 mutG S ABC-2 family transporter protein
OFLKEHFF_03243 3.3e-119 spaE S ABC-2 family transporter protein
OFLKEHFF_03244 1.6e-123 mutF V ABC transporter, ATP-binding protein
OFLKEHFF_03245 1.3e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OFLKEHFF_03246 1.9e-164 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OFLKEHFF_03247 4e-108 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OFLKEHFF_03248 2.1e-205 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OFLKEHFF_03249 3.4e-57 yvbF K Belongs to the GbsR family
OFLKEHFF_03250 1.6e-107 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OFLKEHFF_03251 4.8e-168 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OFLKEHFF_03252 8.6e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OFLKEHFF_03253 1.7e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OFLKEHFF_03254 2.5e-95 yvbF K Belongs to the GbsR family
OFLKEHFF_03255 4.4e-104 yvbG U UPF0056 membrane protein
OFLKEHFF_03256 3.1e-114 exoY M Membrane
OFLKEHFF_03257 3.2e-309 tcaA S response to antibiotic
OFLKEHFF_03258 3.6e-79 yvbK 3.1.3.25 K acetyltransferase
OFLKEHFF_03259 2.3e-205 EGP Major facilitator Superfamily
OFLKEHFF_03260 1.1e-172
OFLKEHFF_03261 2e-123 S GlcNAc-PI de-N-acetylase
OFLKEHFF_03262 6.8e-141 C WbqC-like protein family
OFLKEHFF_03263 1.4e-140 M Protein involved in cellulose biosynthesis
OFLKEHFF_03264 6.3e-219 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OFLKEHFF_03265 7e-167 5.1.3.2 M GDP-mannose 4,6 dehydratase
OFLKEHFF_03266 4.6e-213 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OFLKEHFF_03267 1.9e-250 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OFLKEHFF_03268 5.1e-224 ywaD 3.4.11.10, 3.4.11.6 S PA domain
OFLKEHFF_03269 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OFLKEHFF_03270 1.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
OFLKEHFF_03271 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OFLKEHFF_03272 1e-215 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OFLKEHFF_03273 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OFLKEHFF_03274 1.7e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OFLKEHFF_03276 1.2e-247 araE EGP Major facilitator Superfamily
OFLKEHFF_03277 2.1e-199 araR K transcriptional
OFLKEHFF_03278 5.4e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFLKEHFF_03279 1.9e-124 yvbU K Transcriptional regulator
OFLKEHFF_03280 3.5e-150 yvbV EG EamA-like transporter family
OFLKEHFF_03281 5e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
OFLKEHFF_03283 4e-148 ybbH_1 K RpiR family transcriptional regulator
OFLKEHFF_03284 1.6e-293 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
OFLKEHFF_03285 1.3e-219 gntP EG COG2610 H gluconate symporter and related permeases
OFLKEHFF_03286 1.1e-130 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OFLKEHFF_03287 3.3e-264 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OFLKEHFF_03288 5.1e-133 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OFLKEHFF_03289 6.4e-205 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFLKEHFF_03290 1.4e-117 yvfI K COG2186 Transcriptional regulators
OFLKEHFF_03291 4.2e-295 yvfH C L-lactate permease
OFLKEHFF_03292 2.2e-230 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OFLKEHFF_03293 2.7e-32 yvfG S YvfG protein
OFLKEHFF_03294 1.7e-179 yvfF GM Exopolysaccharide biosynthesis protein
OFLKEHFF_03295 4.6e-216 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OFLKEHFF_03296 3.2e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
OFLKEHFF_03297 7.2e-104 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OFLKEHFF_03298 2.3e-268 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFLKEHFF_03299 2e-186 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
OFLKEHFF_03300 8.9e-198 epsI GM pyruvyl transferase
OFLKEHFF_03301 2.7e-191 epsH GT2 S Glycosyltransferase like family 2
OFLKEHFF_03302 9.4e-203 epsG S EpsG family
OFLKEHFF_03303 7.2e-198 epsF GT4 M Glycosyl transferases group 1
OFLKEHFF_03304 1.7e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OFLKEHFF_03305 1.9e-214 epsD GT4 M Glycosyl transferase 4-like
OFLKEHFF_03306 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
OFLKEHFF_03307 4.6e-115 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
OFLKEHFF_03308 3.9e-117 ywqC M biosynthesis protein
OFLKEHFF_03309 5.1e-78 slr K transcriptional
OFLKEHFF_03310 4.4e-240 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OFLKEHFF_03311 6.6e-85 ywjB H RibD C-terminal domain
OFLKEHFF_03312 4.8e-133 CH FAD binding domain
OFLKEHFF_03313 2.5e-74 S Metallo-beta-lactamase superfamily
OFLKEHFF_03314 3e-105 yyaS S Membrane
OFLKEHFF_03315 4.6e-83 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OFLKEHFF_03316 1.2e-93 padC Q Phenolic acid decarboxylase
OFLKEHFF_03317 7.2e-40 MA20_18690 S Protein of unknown function (DUF3237)
OFLKEHFF_03318 6.1e-31 S Protein of unknown function (DUF1433)
OFLKEHFF_03320 8.8e-22 S Protein of unknown function (DUF1433)
OFLKEHFF_03321 1.4e-16 S Protein of unknown function (DUF1433)
OFLKEHFF_03322 6.8e-230 I Pfam Lipase (class 3)
OFLKEHFF_03323 7.6e-33
OFLKEHFF_03325 9.7e-280 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
OFLKEHFF_03326 3e-205 rafB P LacY proton/sugar symporter
OFLKEHFF_03327 1.9e-175 scrR K transcriptional
OFLKEHFF_03328 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OFLKEHFF_03329 2.3e-34 yraN K Transcriptional regulator
OFLKEHFF_03330 1.4e-12
OFLKEHFF_03331 6.4e-102 yvdD 3.2.2.10 S Belongs to the LOG family
OFLKEHFF_03332 4.1e-50 yvdC S MazG nucleotide pyrophosphohydrolase domain
OFLKEHFF_03333 2.6e-278 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
OFLKEHFF_03334 4.1e-104 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OFLKEHFF_03335 6.4e-179 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OFLKEHFF_03336 7.7e-77 M Ribonuclease
OFLKEHFF_03337 3.2e-130 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
OFLKEHFF_03338 1.4e-35 crh G Phosphocarrier protein Chr
OFLKEHFF_03339 1.2e-169 whiA K May be required for sporulation
OFLKEHFF_03340 9.4e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OFLKEHFF_03341 3.3e-166 rapZ S Displays ATPase and GTPase activities
OFLKEHFF_03342 5.5e-86 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OFLKEHFF_03343 9.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OFLKEHFF_03344 6.4e-111 usp CBM50 M protein conserved in bacteria
OFLKEHFF_03345 1.4e-267 S COG0457 FOG TPR repeat
OFLKEHFF_03346 1.5e-181 sasA T Histidine kinase
OFLKEHFF_03347 4.4e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFLKEHFF_03348 0.0 msbA2 3.6.3.44 V ABC transporter
OFLKEHFF_03349 6.5e-108 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
OFLKEHFF_03350 5.8e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OFLKEHFF_03351 1.3e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OFLKEHFF_03352 4.4e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OFLKEHFF_03353 2.6e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OFLKEHFF_03354 2.7e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OFLKEHFF_03355 1.4e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OFLKEHFF_03356 4.7e-200 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OFLKEHFF_03357 3.1e-138 yvpB NU protein conserved in bacteria
OFLKEHFF_03358 2.3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
OFLKEHFF_03359 1e-111 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OFLKEHFF_03360 1.7e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OFLKEHFF_03361 2.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OFLKEHFF_03362 1.8e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OFLKEHFF_03363 4.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OFLKEHFF_03364 4.4e-132 yvoA K transcriptional
OFLKEHFF_03365 1.7e-166 yxaG 1.13.11.24 S AraC-like ligand binding domain
OFLKEHFF_03366 1.4e-96 yxaF K Transcriptional regulator
OFLKEHFF_03367 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
OFLKEHFF_03368 9.1e-46 yvlD S Membrane
OFLKEHFF_03369 9.6e-26 pspB KT PspC domain
OFLKEHFF_03370 5.6e-163 yvlB S Putative adhesin
OFLKEHFF_03371 4e-46 yvlA
OFLKEHFF_03372 3.6e-30 yvkN
OFLKEHFF_03373 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OFLKEHFF_03374 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OFLKEHFF_03375 7.6e-33 csbA S protein conserved in bacteria
OFLKEHFF_03376 0.0 yvkC 2.7.9.2 GT Phosphotransferase
OFLKEHFF_03377 9.2e-93 yvkB K Transcriptional regulator
OFLKEHFF_03378 6.5e-222 yvkA EGP Major facilitator Superfamily
OFLKEHFF_03379 4.9e-25 yuaB
OFLKEHFF_03380 6.6e-218 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OFLKEHFF_03381 1.5e-55 swrA S Swarming motility protein
OFLKEHFF_03382 3.2e-248 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
OFLKEHFF_03383 1.5e-189 ywoF P Right handed beta helix region
OFLKEHFF_03384 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OFLKEHFF_03385 2.3e-122 ftsE D cell division ATP-binding protein FtsE
OFLKEHFF_03386 5.8e-34 cccB C COG2010 Cytochrome c, mono- and diheme variants
OFLKEHFF_03387 1.5e-147 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
OFLKEHFF_03388 9.4e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OFLKEHFF_03389 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OFLKEHFF_03390 2.4e-101 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OFLKEHFF_03391 1.7e-66
OFLKEHFF_03392 1e-09 fliT S bacterial-type flagellum organization
OFLKEHFF_03393 7e-63 fliS N flagellar protein FliS
OFLKEHFF_03394 1.9e-238 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OFLKEHFF_03395 1.9e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OFLKEHFF_03396 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OFLKEHFF_03397 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OFLKEHFF_03398 5.8e-79 yviE
OFLKEHFF_03399 2.6e-161 flgL N Belongs to the bacterial flagellin family
OFLKEHFF_03400 1.6e-272 flgK N flagellar hook-associated protein
OFLKEHFF_03401 5.4e-78 flgN NOU FlgN protein
OFLKEHFF_03402 8.8e-38 flgM KNU Negative regulator of flagellin synthesis
OFLKEHFF_03403 4.3e-71 yvyF S flagellar protein
OFLKEHFF_03404 5.6e-63 comFC S Phosphoribosyl transferase domain
OFLKEHFF_03405 8.2e-42 comFB S Late competence development protein ComFB
OFLKEHFF_03406 1.1e-248 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OFLKEHFF_03407 1.3e-154 degV S protein conserved in bacteria
OFLKEHFF_03408 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFLKEHFF_03409 6.9e-180 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OFLKEHFF_03410 4.7e-117 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
OFLKEHFF_03411 5.1e-170 yvhJ K Transcriptional regulator
OFLKEHFF_03412 2.4e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OFLKEHFF_03413 4.3e-225 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
OFLKEHFF_03414 2.1e-140 tuaG GT2 M Glycosyltransferase like family 2
OFLKEHFF_03415 1.6e-107 tuaF M protein involved in exopolysaccharide biosynthesis
OFLKEHFF_03416 2.9e-252 tuaE M Teichuronic acid biosynthesis protein
OFLKEHFF_03417 1.6e-244 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OFLKEHFF_03418 2.4e-212 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
OFLKEHFF_03419 1.5e-253 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OFLKEHFF_03420 1.4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OFLKEHFF_03421 1.1e-262 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OFLKEHFF_03422 0.0 lytB 3.5.1.28 D Stage II sporulation protein
OFLKEHFF_03423 5.6e-47
OFLKEHFF_03424 8e-147 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OFLKEHFF_03425 1.5e-206 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OFLKEHFF_03426 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OFLKEHFF_03427 5.1e-271 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OFLKEHFF_03428 1.7e-151 tagG GM Transport permease protein
OFLKEHFF_03429 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OFLKEHFF_03430 2.7e-272 M Glycosyltransferase like family 2
OFLKEHFF_03431 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OFLKEHFF_03432 2.7e-140 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OFLKEHFF_03433 9e-204 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OFLKEHFF_03434 3.7e-221 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OFLKEHFF_03435 2.5e-183 pmi 5.3.1.8 G mannose-6-phosphate isomerase
OFLKEHFF_03436 5e-252 gerBA EG Spore germination protein
OFLKEHFF_03437 7.5e-192 gerBB E Spore germination protein
OFLKEHFF_03438 2.9e-207 gerAC S Spore germination protein
OFLKEHFF_03439 1.3e-257 GT2,GT4 J Glycosyl transferase family 2
OFLKEHFF_03440 1.4e-240 ywtG EGP Major facilitator Superfamily
OFLKEHFF_03441 2.4e-173 ywtF K Transcriptional regulator
OFLKEHFF_03442 3.7e-154 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
OFLKEHFF_03444 2.4e-10 yttA 2.7.13.3 S Pfam Transposase IS66
OFLKEHFF_03445 6.3e-33 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OFLKEHFF_03446 6.1e-23
OFLKEHFF_03447 7.3e-228 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OFLKEHFF_03448 1.5e-19 ywtC
OFLKEHFF_03449 1.2e-216 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
OFLKEHFF_03450 5.1e-70 pgsC S biosynthesis protein
OFLKEHFF_03451 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
OFLKEHFF_03452 1.2e-197 gerKA EG Spore germination protein
OFLKEHFF_03453 6.7e-177 gerKB E Spore germination protein
OFLKEHFF_03454 7e-193 gerKC S Spore germination B3/ GerAC like, C-terminal
OFLKEHFF_03455 1.1e-173 rbsR K transcriptional
OFLKEHFF_03456 6.1e-152 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OFLKEHFF_03457 7.6e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OFLKEHFF_03458 3.8e-271 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OFLKEHFF_03459 3.5e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
OFLKEHFF_03460 1.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
OFLKEHFF_03461 6e-86 batE T Sh3 type 3 domain protein
OFLKEHFF_03462 4.3e-89 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
OFLKEHFF_03463 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
OFLKEHFF_03464 1.3e-304 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OFLKEHFF_03465 7.1e-164 alsR K LysR substrate binding domain
OFLKEHFF_03466 4.3e-234 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OFLKEHFF_03467 1.5e-118 ywrJ
OFLKEHFF_03468 1.8e-119 cotB
OFLKEHFF_03469 9.4e-203 cotH M Spore Coat
OFLKEHFF_03470 1.1e-06
OFLKEHFF_03471 1.1e-107 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OFLKEHFF_03472 3.7e-293 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OFLKEHFF_03473 7.5e-80 ywrC K Transcriptional regulator
OFLKEHFF_03474 2e-98 ywrB P Chromate transporter
OFLKEHFF_03475 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
OFLKEHFF_03476 8.5e-120 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
OFLKEHFF_03477 6.6e-25
OFLKEHFF_03478 3.7e-97 ywqJ S Pre-toxin TG
OFLKEHFF_03479 3.7e-69 S Immunity protein Imm6
OFLKEHFF_03480 1.6e-65 S SMI1 / KNR4 family (SUKH-1)
OFLKEHFF_03481 3.8e-63
OFLKEHFF_03482 2.5e-74 S SMI1 / KNR4 family
OFLKEHFF_03483 3.6e-65 S SMI1 / KNR4 family (SUKH-1)
OFLKEHFF_03484 1e-237 ywqJ S Pre-toxin TG
OFLKEHFF_03485 1e-27 ywqI S Family of unknown function (DUF5344)
OFLKEHFF_03486 1.2e-23 S Domain of unknown function (DUF5082)
OFLKEHFF_03487 5.8e-146 ywqG S Domain of unknown function (DUF1963)
OFLKEHFF_03488 8e-241 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OFLKEHFF_03489 1.6e-137 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
OFLKEHFF_03490 5.1e-114 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
OFLKEHFF_03491 1.2e-105 ywqC M biosynthesis protein
OFLKEHFF_03492 2.6e-15
OFLKEHFF_03493 2e-302 ywqB S SWIM zinc finger
OFLKEHFF_03494 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OFLKEHFF_03495 5.5e-150 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
OFLKEHFF_03496 3.2e-136 glcR K DeoR C terminal sensor domain
OFLKEHFF_03497 1.4e-56 ssbB L Single-stranded DNA-binding protein
OFLKEHFF_03498 9.4e-56 ywpG
OFLKEHFF_03499 9.9e-68 ywpF S YwpF-like protein
OFLKEHFF_03500 5.9e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OFLKEHFF_03501 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OFLKEHFF_03502 5e-193 S aspartate phosphatase
OFLKEHFF_03503 5.5e-139 flhP N flagellar basal body
OFLKEHFF_03504 1e-126 flhO N flagellar basal body
OFLKEHFF_03505 2.7e-180 mbl D Rod shape-determining protein
OFLKEHFF_03506 1.8e-44 spoIIID K Stage III sporulation protein D
OFLKEHFF_03507 4.2e-71 ywoH K transcriptional
OFLKEHFF_03508 7.1e-212 ywoG EGP Major facilitator Superfamily
OFLKEHFF_03509 3.4e-269 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
OFLKEHFF_03510 3.7e-241 ywoD EGP Major facilitator superfamily
OFLKEHFF_03511 1.3e-99 phzA Q Isochorismatase family
OFLKEHFF_03512 1.3e-226 amt P Ammonium transporter
OFLKEHFF_03513 2.2e-57 nrgB K Belongs to the P(II) protein family
OFLKEHFF_03514 1.5e-206 ftsW D Belongs to the SEDS family
OFLKEHFF_03515 1.3e-99 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OFLKEHFF_03516 4e-69 ywnJ S VanZ like family
OFLKEHFF_03517 1.6e-120 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
OFLKEHFF_03518 2.5e-86 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
OFLKEHFF_03519 6.9e-11 ywnC S Family of unknown function (DUF5362)
OFLKEHFF_03520 2.3e-67 ywnF S Family of unknown function (DUF5392)
OFLKEHFF_03521 7.9e-274 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OFLKEHFF_03522 9.1e-52 ywnC S Family of unknown function (DUF5362)
OFLKEHFF_03523 6.9e-89 ywnB S NAD(P)H-binding
OFLKEHFF_03524 6.1e-67 ywnA K Transcriptional regulator
OFLKEHFF_03525 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OFLKEHFF_03526 1.2e-61 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OFLKEHFF_03527 2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OFLKEHFF_03528 1.2e-09 csbD K CsbD-like
OFLKEHFF_03529 2.2e-82 ywmF S Peptidase M50
OFLKEHFF_03530 1.1e-92 S response regulator aspartate phosphatase
OFLKEHFF_03532 5e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OFLKEHFF_03533 3.5e-143 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OFLKEHFF_03535 8.1e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
OFLKEHFF_03536 7.4e-113 ywmC S protein containing a von Willebrand factor type A (vWA) domain
OFLKEHFF_03537 1.4e-179 spoIID D Stage II sporulation protein D
OFLKEHFF_03538 8.2e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OFLKEHFF_03539 6e-126 ywmB S TATA-box binding
OFLKEHFF_03540 6.2e-32 ywzB S membrane
OFLKEHFF_03541 4.3e-88 ywmA
OFLKEHFF_03542 5.3e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OFLKEHFF_03543 5.9e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OFLKEHFF_03544 2.3e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OFLKEHFF_03545 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OFLKEHFF_03546 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OFLKEHFF_03547 3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OFLKEHFF_03548 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OFLKEHFF_03549 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
OFLKEHFF_03550 8.2e-61 atpI S ATP synthase
OFLKEHFF_03551 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OFLKEHFF_03552 9.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OFLKEHFF_03553 6.1e-94 ywlG S Belongs to the UPF0340 family
OFLKEHFF_03554 4.6e-79 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
OFLKEHFF_03555 2.7e-71 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OFLKEHFF_03556 9.6e-87 mntP P Probably functions as a manganese efflux pump
OFLKEHFF_03557 4.4e-186 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OFLKEHFF_03558 3.7e-73 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
OFLKEHFF_03559 2.7e-115 spoIIR S stage II sporulation protein R
OFLKEHFF_03560 8.2e-58 ywlA S Uncharacterised protein family (UPF0715)
OFLKEHFF_03562 9.1e-153 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OFLKEHFF_03563 1.8e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OFLKEHFF_03564 2.4e-65 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFLKEHFF_03565 2.9e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
OFLKEHFF_03566 1.1e-151 ywkB S Membrane transport protein
OFLKEHFF_03567 0.0 sfcA 1.1.1.38 C malic enzyme
OFLKEHFF_03568 1.6e-100 tdk 2.7.1.21 F thymidine kinase
OFLKEHFF_03569 1.1e-32 rpmE J Binds the 23S rRNA
OFLKEHFF_03570 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OFLKEHFF_03571 2.1e-174 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
OFLKEHFF_03572 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OFLKEHFF_03573 4.2e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OFLKEHFF_03574 2.7e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
OFLKEHFF_03575 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
OFLKEHFF_03576 1.2e-91 ywjG S Domain of unknown function (DUF2529)
OFLKEHFF_03577 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OFLKEHFF_03578 7e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OFLKEHFF_03579 0.0 fadF C COG0247 Fe-S oxidoreductase
OFLKEHFF_03580 2.5e-201 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OFLKEHFF_03581 1.6e-174 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
OFLKEHFF_03582 1.6e-42 ywjC
OFLKEHFF_03583 0.0 ywjA V ABC transporter
OFLKEHFF_03584 1e-279 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OFLKEHFF_03585 1.7e-117 narI 1.7.5.1 C nitrate reductase, gamma
OFLKEHFF_03586 2.8e-86 narJ 1.7.5.1 C nitrate reductase
OFLKEHFF_03587 1e-289 narH 1.7.5.1 C Nitrate reductase, beta
OFLKEHFF_03588 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OFLKEHFF_03589 2.5e-75 arfM T cyclic nucleotide binding
OFLKEHFF_03590 2.1e-126 ywiC S YwiC-like protein
OFLKEHFF_03591 1.4e-125 fnr K helix_turn_helix, cAMP Regulatory protein
OFLKEHFF_03592 5.6e-209 narK P COG2223 Nitrate nitrite transporter
OFLKEHFF_03593 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OFLKEHFF_03594 1.1e-71 ywiB S protein conserved in bacteria
OFLKEHFF_03595 2.8e-191 ywhL CO amine dehydrogenase activity
OFLKEHFF_03596 4.3e-73 S aspartate phosphatase
OFLKEHFF_03598 2.7e-168 speB 3.5.3.11 E Belongs to the arginase family
OFLKEHFF_03599 1.6e-157 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OFLKEHFF_03600 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OFLKEHFF_03601 2.9e-70
OFLKEHFF_03602 1.1e-89 ywhD S YwhD family
OFLKEHFF_03603 2.1e-117 ywhC S Peptidase family M50
OFLKEHFF_03604 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
OFLKEHFF_03605 2.2e-67 ywhA K Transcriptional regulator
OFLKEHFF_03606 1.9e-240 yhdG_1 E C-terminus of AA_permease
OFLKEHFF_03607 3.5e-88 ywgA 2.1.1.72, 3.1.21.3
OFLKEHFF_03608 1.5e-252 ywfO S COG1078 HD superfamily phosphohydrolases
OFLKEHFF_03609 6.9e-36 ywzC S Belongs to the UPF0741 family
OFLKEHFF_03610 1.3e-105 rsfA_1
OFLKEHFF_03611 6.9e-50 padR K PadR family transcriptional regulator
OFLKEHFF_03612 9e-85 S membrane
OFLKEHFF_03613 7e-151 V ABC transporter, ATP-binding protein
OFLKEHFF_03614 7e-162 yhcI S ABC transporter (permease)
OFLKEHFF_03617 1.9e-164
OFLKEHFF_03619 8.3e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OFLKEHFF_03620 9.1e-156 cysL K Transcriptional regulator
OFLKEHFF_03621 1.3e-150 MA20_14895 S Conserved hypothetical protein 698
OFLKEHFF_03622 2.4e-173 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
OFLKEHFF_03623 1.1e-144 ywfI C May function as heme-dependent peroxidase
OFLKEHFF_03624 1.2e-138 IQ Enoyl-(Acyl carrier protein) reductase
OFLKEHFF_03625 2.9e-229 ywfG 2.6.1.83 E Aminotransferase class I and II
OFLKEHFF_03626 6.1e-208 bacE EGP Major facilitator Superfamily
OFLKEHFF_03627 4e-262 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
OFLKEHFF_03628 5.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OFLKEHFF_03629 4.9e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
OFLKEHFF_03630 1.4e-110 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
OFLKEHFF_03631 6e-214 ywfA EGP Major facilitator Superfamily
OFLKEHFF_03632 3.4e-198 tcaB EGP Major facilitator Superfamily
OFLKEHFF_03633 3.3e-256 lysP E amino acid
OFLKEHFF_03634 0.0 rocB E arginine degradation protein
OFLKEHFF_03635 8.1e-293 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OFLKEHFF_03636 1.1e-245 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OFLKEHFF_03637 2.6e-61
OFLKEHFF_03638 5.6e-85 spsL 5.1.3.13 M Spore Coat
OFLKEHFF_03639 7.9e-157 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OFLKEHFF_03640 1.3e-176 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OFLKEHFF_03641 2e-132 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OFLKEHFF_03642 2.9e-166 spsG M Spore Coat
OFLKEHFF_03643 1e-123 spsF M Spore Coat
OFLKEHFF_03644 1.4e-209 spsE 2.5.1.56 M acid synthase
OFLKEHFF_03645 1.3e-151 spsD 2.3.1.210 K Spore Coat
OFLKEHFF_03646 1.1e-217 spsC E Belongs to the DegT DnrJ EryC1 family
OFLKEHFF_03647 1.7e-257 spsB M Capsule polysaccharide biosynthesis protein
OFLKEHFF_03648 2.1e-140 spsA M Spore Coat
OFLKEHFF_03649 1.5e-63 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OFLKEHFF_03650 1.3e-55 ywdK S small membrane protein
OFLKEHFF_03651 7.3e-226 ywdJ F Xanthine uracil
OFLKEHFF_03652 1.1e-37 ywdI S Family of unknown function (DUF5327)
OFLKEHFF_03653 5.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OFLKEHFF_03654 1.8e-147 ywdF GT2,GT4 S Glycosyltransferase like family 2
OFLKEHFF_03655 7.3e-144 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OFLKEHFF_03656 2.6e-20 ywdA
OFLKEHFF_03657 3.3e-272 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
OFLKEHFF_03658 4.6e-247 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OFLKEHFF_03659 1.2e-149 sacT K transcriptional antiterminator
OFLKEHFF_03661 0.0 vpr O Belongs to the peptidase S8 family
OFLKEHFF_03662 6.4e-182 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OFLKEHFF_03663 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
OFLKEHFF_03664 1.8e-207 rodA D Belongs to the SEDS family
OFLKEHFF_03665 8e-71 ysnE K acetyltransferase
OFLKEHFF_03666 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
OFLKEHFF_03667 1.3e-60 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OFLKEHFF_03668 2.3e-110 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OFLKEHFF_03669 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OFLKEHFF_03670 1.6e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OFLKEHFF_03671 8.4e-27 ywzA S membrane
OFLKEHFF_03672 1.1e-281 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OFLKEHFF_03673 7.3e-209 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OFLKEHFF_03674 1.3e-59 gtcA S GtrA-like protein
OFLKEHFF_03675 8.8e-97 ywcC K Bacterial regulatory proteins, tetR family
OFLKEHFF_03677 8.3e-125 H Methionine biosynthesis protein MetW
OFLKEHFF_03678 8.5e-122 S Streptomycin biosynthesis protein StrF
OFLKEHFF_03679 1.1e-107 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OFLKEHFF_03680 5e-232 ywbN P Dyp-type peroxidase family protein
OFLKEHFF_03681 4.7e-128 ycdO P periplasmic lipoprotein involved in iron transport
OFLKEHFF_03682 5.6e-195 P COG0672 High-affinity Fe2 Pb2 permease
OFLKEHFF_03683 7.4e-110 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OFLKEHFF_03684 6.7e-129 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OFLKEHFF_03685 7.6e-150 ywbI K Transcriptional regulator
OFLKEHFF_03686 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OFLKEHFF_03687 2.9e-109 ywbG M effector of murein hydrolase
OFLKEHFF_03688 1.5e-26 ywbE S Uncharacterized conserved protein (DUF2196)
OFLKEHFF_03689 8.2e-129 mta K transcriptional
OFLKEHFF_03690 9.3e-156 yjfC O Predicted Zn-dependent protease (DUF2268)
OFLKEHFF_03693 1e-55 K Transcriptional regulator
OFLKEHFF_03694 2.4e-220 ywbD 2.1.1.191 J Methyltransferase
OFLKEHFF_03695 2.9e-66 ywbC 4.4.1.5 E glyoxalase
OFLKEHFF_03696 4.3e-242 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OFLKEHFF_03697 1.1e-248 epr 3.4.21.62 O Belongs to the peptidase S8 family
OFLKEHFF_03698 3.1e-161 gspA M General stress
OFLKEHFF_03699 1.6e-48 ywaE K Transcriptional regulator
OFLKEHFF_03700 5.7e-196 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OFLKEHFF_03701 2.9e-116 ywaC 2.7.6.5 S protein conserved in bacteria
OFLKEHFF_03702 1.9e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
OFLKEHFF_03703 4.7e-12 S D-Ala-teichoic acid biosynthesis protein
OFLKEHFF_03704 2.4e-289 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFLKEHFF_03705 5.9e-227 dltB M membrane protein involved in D-alanine export
OFLKEHFF_03706 5.6e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OFLKEHFF_03707 1.6e-224 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OFLKEHFF_03708 1.8e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OFLKEHFF_03709 2.8e-249 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OFLKEHFF_03710 4.3e-50 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
OFLKEHFF_03711 1.7e-241 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OFLKEHFF_03712 7.5e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
OFLKEHFF_03713 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
OFLKEHFF_03714 5.2e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OFLKEHFF_03715 4.4e-170 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFLKEHFF_03716 5.7e-178 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OFLKEHFF_03717 5.7e-166 cbrA3 P Periplasmic binding protein
OFLKEHFF_03718 4.1e-51 arsR K transcriptional
OFLKEHFF_03719 9.7e-223 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OFLKEHFF_03720 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OFLKEHFF_03721 4.5e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OFLKEHFF_03722 5.7e-250 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
OFLKEHFF_03723 3.3e-152 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OFLKEHFF_03724 9.1e-285 cydD V ATP-binding protein
OFLKEHFF_03725 8.3e-307 cydD V ATP-binding
OFLKEHFF_03726 1.6e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
OFLKEHFF_03727 3.2e-264 cydA 1.10.3.14 C oxidase, subunit
OFLKEHFF_03728 2.1e-212 cimH C COG3493 Na citrate symporter
OFLKEHFF_03729 3.5e-149 yxkH G Polysaccharide deacetylase
OFLKEHFF_03730 1.7e-204 msmK P Belongs to the ABC transporter superfamily
OFLKEHFF_03731 8.6e-154 lrp QT PucR C-terminal helix-turn-helix domain
OFLKEHFF_03732 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OFLKEHFF_03734 1e-79 yxkC S Domain of unknown function (DUF4352)
OFLKEHFF_03735 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OFLKEHFF_03736 2.3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OFLKEHFF_03739 8e-82 yxjI S LURP-one-related
OFLKEHFF_03740 2.7e-213 yxjG 2.1.1.14 E Methionine synthase
OFLKEHFF_03741 5.7e-142 rlmA 2.1.1.187 Q Methyltransferase domain
OFLKEHFF_03742 5.7e-207 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OFLKEHFF_03743 1.2e-67 T Domain of unknown function (DUF4163)
OFLKEHFF_03744 6.7e-50 yxiS
OFLKEHFF_03745 4.2e-07
OFLKEHFF_03746 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
OFLKEHFF_03747 4.4e-220 citH C Citrate transporter
OFLKEHFF_03748 7.7e-137 exoK GH16 M licheninase activity
OFLKEHFF_03749 1.2e-56 licT K transcriptional antiterminator
OFLKEHFF_03750 1.5e-60 licT K transcriptional antiterminator
OFLKEHFF_03751 6.2e-219 yxiO S COG2270 Permeases of the major facilitator superfamily
OFLKEHFF_03752 3.7e-255 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
OFLKEHFF_03755 8.6e-60 S SMI1-KNR4 cell-wall
OFLKEHFF_03756 1.7e-79 yxiI S Protein of unknown function (DUF2716)
OFLKEHFF_03758 1.6e-22
OFLKEHFF_03759 2.1e-11 S YxiJ-like protein
OFLKEHFF_03760 3.9e-111
OFLKEHFF_03761 2.7e-71
OFLKEHFF_03762 4e-31
OFLKEHFF_03765 3.4e-65 yxiG
OFLKEHFF_03766 6.9e-15 yxiG
OFLKEHFF_03767 8.5e-15 yxiG
OFLKEHFF_03768 0.0 wapA M COG3209 Rhs family protein
OFLKEHFF_03769 1.2e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
OFLKEHFF_03770 1.5e-142 yxxF EG EamA-like transporter family
OFLKEHFF_03771 1e-70 yxiE T Belongs to the universal stress protein A family
OFLKEHFF_03772 0.0 L HKD family nuclease
OFLKEHFF_03773 1.6e-64 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OFLKEHFF_03774 5e-265 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OFLKEHFF_03775 8.5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
OFLKEHFF_03776 1.7e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
OFLKEHFF_03777 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OFLKEHFF_03778 4.7e-230 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
OFLKEHFF_03779 1e-168 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
OFLKEHFF_03780 2.5e-248 lysP E amino acid
OFLKEHFF_03781 1.5e-231 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
OFLKEHFF_03782 5.2e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OFLKEHFF_03783 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OFLKEHFF_03784 3.1e-170 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OFLKEHFF_03785 9.2e-147 yidA S hydrolases of the HAD superfamily
OFLKEHFF_03790 7.9e-21 yxeD
OFLKEHFF_03791 2.7e-35
OFLKEHFF_03792 7e-170 fhuD P Periplasmic binding protein
OFLKEHFF_03793 3.6e-55 yxeA S Protein of unknown function (DUF1093)
OFLKEHFF_03794 0.0 yxdM V ABC transporter (permease)
OFLKEHFF_03795 6.7e-139 yxdL V ABC transporter, ATP-binding protein
OFLKEHFF_03796 2.1e-174 T PhoQ Sensor
OFLKEHFF_03797 2.3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFLKEHFF_03798 1.3e-151 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
OFLKEHFF_03799 3.6e-146 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
OFLKEHFF_03800 2.3e-164 iolH G Xylose isomerase-like TIM barrel
OFLKEHFF_03801 2.4e-192 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
OFLKEHFF_03802 3.4e-228 iolF EGP Major facilitator Superfamily
OFLKEHFF_03803 1.3e-173 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
OFLKEHFF_03804 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
OFLKEHFF_03805 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
OFLKEHFF_03806 2.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
OFLKEHFF_03807 1.8e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OFLKEHFF_03808 3.4e-135 iolR K COG1349 Transcriptional regulators of sugar metabolism
OFLKEHFF_03809 1.9e-172 iolS C Aldo keto reductase
OFLKEHFF_03810 8.1e-244 csbC EGP Major facilitator Superfamily
OFLKEHFF_03811 0.0 htpG O Molecular chaperone. Has ATPase activity
OFLKEHFF_03812 6.5e-148 IQ Enoyl-(Acyl carrier protein) reductase
OFLKEHFF_03813 1.6e-100 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OFLKEHFF_03814 4.1e-193 desK 2.7.13.3 T Histidine kinase
OFLKEHFF_03815 5.3e-195 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
OFLKEHFF_03816 1e-207 yxbF K Bacterial regulatory proteins, tetR family
OFLKEHFF_03817 9.9e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OFLKEHFF_03818 3.2e-138 S PQQ-like domain
OFLKEHFF_03819 1.6e-57 S Family of unknown function (DUF5391)
OFLKEHFF_03820 5.1e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
OFLKEHFF_03821 2.3e-199 EGP Major facilitator Superfamily
OFLKEHFF_03822 2.6e-66 yxaI S membrane protein domain
OFLKEHFF_03823 1.4e-119 E Ring-cleavage extradiol dioxygenase
OFLKEHFF_03824 1e-104 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
OFLKEHFF_03825 4e-284 ahpF O Alkyl hydroperoxide reductase
OFLKEHFF_03826 6.9e-186 G Major royal jelly protein
OFLKEHFF_03827 1.6e-236 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
OFLKEHFF_03828 3.1e-157 K helix_turn_helix, Deoxyribose operon repressor
OFLKEHFF_03829 1.7e-74 K Integron-associated effector binding protein
OFLKEHFF_03830 1.1e-75 yjhE S Phage tail protein
OFLKEHFF_03831 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
OFLKEHFF_03832 3.1e-78 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
OFLKEHFF_03833 2.4e-142 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
OFLKEHFF_03834 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
OFLKEHFF_03835 4.5e-85 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
OFLKEHFF_03836 4.5e-167 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OFLKEHFF_03837 4.9e-156 S Fusaric acid resistance protein-like
OFLKEHFF_03839 9.8e-24 V Domain of unknown function (DUF3883)
OFLKEHFF_03840 0.0 LO the current gene model (or a revised gene model) may contain a frame shift
OFLKEHFF_03841 5.7e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OFLKEHFF_03842 7.9e-08 S YyzF-like protein
OFLKEHFF_03843 7.4e-206 yycP
OFLKEHFF_03844 4.2e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OFLKEHFF_03845 1.3e-176 C oxidoreductases (related to aryl-alcohol dehydrogenases)
OFLKEHFF_03846 1e-81 yycN 2.3.1.128 K Acetyltransferase
OFLKEHFF_03848 1.5e-195 S Histidine kinase
OFLKEHFF_03849 9.1e-164 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OFLKEHFF_03850 1.3e-252 rocE E amino acid
OFLKEHFF_03851 6.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OFLKEHFF_03852 2.3e-254 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OFLKEHFF_03853 6.4e-197 S Major Facilitator Superfamily
OFLKEHFF_03854 6.2e-239 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
OFLKEHFF_03855 8.3e-71 K PFAM response regulator receiver
OFLKEHFF_03856 6.2e-216 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OFLKEHFF_03857 4.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OFLKEHFF_03858 4.3e-147 yycI S protein conserved in bacteria
OFLKEHFF_03859 2.8e-257 yycH S protein conserved in bacteria
OFLKEHFF_03860 0.0 vicK 2.7.13.3 T Histidine kinase
OFLKEHFF_03861 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OFLKEHFF_03866 3.9e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OFLKEHFF_03867 9.4e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFLKEHFF_03868 6.1e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OFLKEHFF_03869 1.4e-27 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
OFLKEHFF_03871 1.8e-16 yycC K YycC-like protein
OFLKEHFF_03872 5.4e-218 M Glycosyltransferase Family 4
OFLKEHFF_03873 1.3e-193 S Ecdysteroid kinase
OFLKEHFF_03874 2.1e-232 S Carbamoyl-phosphate synthase L chain, ATP binding domain
OFLKEHFF_03875 6.9e-224 M Glycosyltransferase Family 4
OFLKEHFF_03876 1.1e-118 S GlcNAc-PI de-N-acetylase
OFLKEHFF_03877 1.6e-84 KLT COG0515 Serine threonine protein kinase
OFLKEHFF_03878 1.4e-72 rplI J binds to the 23S rRNA
OFLKEHFF_03879 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OFLKEHFF_03880 1.3e-149 yybS S membrane
OFLKEHFF_03882 2.9e-79 cotF M Spore coat protein
OFLKEHFF_03883 1.2e-64 ydeP3 K Transcriptional regulator
OFLKEHFF_03884 8.6e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
OFLKEHFF_03885 1.5e-150 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OFLKEHFF_03886 3.7e-268 sacB 2.4.1.10 GH68 M levansucrase activity
OFLKEHFF_03887 1.5e-302 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
OFLKEHFF_03888 2.1e-109 K FCD domain
OFLKEHFF_03889 2.2e-74 dinB S PFAM DinB family protein
OFLKEHFF_03890 7.1e-54 ypaA S Protein of unknown function (DUF1304)
OFLKEHFF_03891 4.4e-112 drgA C nitroreductase
OFLKEHFF_03892 4.7e-65 ydgJ K Winged helix DNA-binding domain
OFLKEHFF_03893 2e-147 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OFLKEHFF_03894 1.4e-75 yybA 2.3.1.57 K transcriptional
OFLKEHFF_03895 2.2e-71 yjcF S Acetyltransferase (GNAT) domain
OFLKEHFF_03896 4.1e-254 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OFLKEHFF_03897 2.5e-137 ydfC EG EamA-like transporter family
OFLKEHFF_03898 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OFLKEHFF_03899 2.8e-152 yyaK S CAAX protease self-immunity
OFLKEHFF_03900 8.6e-235 ydjK G Sugar (and other) transporter
OFLKEHFF_03901 5.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OFLKEHFF_03902 9e-170 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
OFLKEHFF_03903 7.1e-141 xth 3.1.11.2 L exodeoxyribonuclease III
OFLKEHFF_03904 8.2e-88 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OFLKEHFF_03905 1.4e-96 adaA 3.2.2.21 K Transcriptional regulator
OFLKEHFF_03906 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OFLKEHFF_03907 8.4e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OFLKEHFF_03908 3.6e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
OFLKEHFF_03909 9.8e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OFLKEHFF_03910 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OFLKEHFF_03911 2.3e-33 yyzM S protein conserved in bacteria
OFLKEHFF_03912 1.6e-169 yyaD S Membrane
OFLKEHFF_03913 2.4e-107 yyaC S Sporulation protein YyaC
OFLKEHFF_03914 2e-147 spo0J K Belongs to the ParB family
OFLKEHFF_03915 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
OFLKEHFF_03916 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OFLKEHFF_03917 3.9e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OFLKEHFF_03918 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OFLKEHFF_03919 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OFLKEHFF_03920 8.2e-106 jag S single-stranded nucleic acid binding R3H
OFLKEHFF_03921 7.3e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OFLKEHFF_03922 9.1e-51 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)