ORF_ID e_value Gene_name EC_number CAZy COGs Description
PHLHKCMP_00001 1.5e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHLHKCMP_00002 4.9e-123 XK27_01040 S Protein of unknown function (DUF1129)
PHLHKCMP_00003 3.1e-198 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PHLHKCMP_00004 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
PHLHKCMP_00005 1.3e-154 spo0J K Belongs to the ParB family
PHLHKCMP_00006 1.8e-136 soj D Sporulation initiation inhibitor
PHLHKCMP_00007 5.1e-148 noc K Belongs to the ParB family
PHLHKCMP_00008 1.7e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PHLHKCMP_00009 2.7e-225 nupG F Nucleoside
PHLHKCMP_00010 2.3e-125 ydgH S MMPL family
PHLHKCMP_00011 4e-264 M domain protein
PHLHKCMP_00012 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
PHLHKCMP_00013 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHLHKCMP_00014 2.2e-294 glpQ 3.1.4.46 C phosphodiesterase
PHLHKCMP_00015 2.3e-42
PHLHKCMP_00016 1.3e-114
PHLHKCMP_00017 2.5e-232 mntH P H( )-stimulated, divalent metal cation uptake system
PHLHKCMP_00018 9e-119 K Bacterial regulatory proteins, tetR family
PHLHKCMP_00019 1.8e-72 K Transcriptional regulator
PHLHKCMP_00020 2.5e-68
PHLHKCMP_00021 2.9e-99 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PHLHKCMP_00022 1.7e-247 tagF 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHLHKCMP_00023 1.7e-77 tagF 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHLHKCMP_00024 7.1e-08 K Bacterial regulatory proteins, tetR family
PHLHKCMP_00025 3.5e-38 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_00026 1.2e-44 L Integrase core domain
PHLHKCMP_00027 1.5e-34
PHLHKCMP_00028 1.5e-12
PHLHKCMP_00029 2.8e-43 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_00030 8.7e-41 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_00031 1.8e-201 G PTS system
PHLHKCMP_00032 6.9e-76 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
PHLHKCMP_00033 1e-90 rpe 5.1.3.1 G Ribulose-phosphate 3 epimerase family
PHLHKCMP_00034 3.5e-217 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHLHKCMP_00035 1.4e-27 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PHLHKCMP_00036 5.7e-71 C FMN binding
PHLHKCMP_00037 5.3e-156 K LysR family
PHLHKCMP_00038 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
PHLHKCMP_00039 3.7e-61 S Elongation factor G-binding protein, N-terminal
PHLHKCMP_00040 2e-64 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
PHLHKCMP_00041 5.3e-121 pnb C nitroreductase
PHLHKCMP_00042 8.3e-119 ung2 3.2.2.27 L Uracil-DNA glycosylase
PHLHKCMP_00043 2.1e-166 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PHLHKCMP_00044 1.8e-202 S Pfam Methyltransferase
PHLHKCMP_00047 7.5e-139 N Cell shape-determining protein MreB
PHLHKCMP_00048 4.3e-21 N Cell shape-determining protein MreB
PHLHKCMP_00049 8.1e-20 N Cell shape-determining protein MreB
PHLHKCMP_00050 1.6e-16
PHLHKCMP_00051 1.9e-18
PHLHKCMP_00052 1.6e-16
PHLHKCMP_00053 5.2e-15
PHLHKCMP_00054 7.2e-17
PHLHKCMP_00055 2.7e-16
PHLHKCMP_00056 4.6e-236 infB M MucBP domain
PHLHKCMP_00057 0.0 bztC D nuclear chromosome segregation
PHLHKCMP_00058 7.3e-83 K MarR family
PHLHKCMP_00059 1.4e-43
PHLHKCMP_00060 2e-38
PHLHKCMP_00062 2.9e-28
PHLHKCMP_00065 2.2e-97 L Integrase
PHLHKCMP_00066 9.6e-51 2.7.7.49 V HNH endonuclease
PHLHKCMP_00067 4.8e-70 S Protein of unknown function (DUF2992)
PHLHKCMP_00069 3.2e-11
PHLHKCMP_00073 2.2e-23 K Bacterial regulatory proteins, tetR family
PHLHKCMP_00074 7e-26
PHLHKCMP_00075 3.9e-50
PHLHKCMP_00076 9.2e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
PHLHKCMP_00077 1.4e-170 2.5.1.74 H UbiA prenyltransferase family
PHLHKCMP_00078 5.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PHLHKCMP_00079 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PHLHKCMP_00080 8.1e-279 pipD E Dipeptidase
PHLHKCMP_00081 3.6e-39
PHLHKCMP_00082 4.8e-29 S CsbD-like
PHLHKCMP_00083 3e-38 S transglycosylase associated protein
PHLHKCMP_00084 3.1e-14
PHLHKCMP_00085 3.5e-36
PHLHKCMP_00086 3.4e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHLHKCMP_00087 6.8e-57
PHLHKCMP_00088 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
PHLHKCMP_00089 1.3e-131
PHLHKCMP_00090 4.8e-176 sepS16B
PHLHKCMP_00091 9.7e-67 gcvH E Glycine cleavage H-protein
PHLHKCMP_00092 4.2e-38 lytE M LysM domain protein
PHLHKCMP_00093 6.9e-162 drrA V ABC transporter
PHLHKCMP_00094 2e-119 drrB U ABC-2 type transporter
PHLHKCMP_00095 1.4e-220 M O-Antigen ligase
PHLHKCMP_00096 2.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
PHLHKCMP_00097 1.6e-196 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PHLHKCMP_00098 4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PHLHKCMP_00099 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PHLHKCMP_00100 7.3e-29 S Protein of unknown function (DUF2929)
PHLHKCMP_00101 0.0 dnaE 2.7.7.7 L DNA polymerase
PHLHKCMP_00102 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PHLHKCMP_00103 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PHLHKCMP_00104 1.5e-74 yeaL S Protein of unknown function (DUF441)
PHLHKCMP_00105 2.5e-169 cvfB S S1 domain
PHLHKCMP_00106 3.2e-164 xerD D recombinase XerD
PHLHKCMP_00107 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PHLHKCMP_00108 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PHLHKCMP_00109 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PHLHKCMP_00110 4.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PHLHKCMP_00111 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PHLHKCMP_00112 3.1e-195 ypbB 5.1.3.1 S Helix-turn-helix domain
PHLHKCMP_00113 1.1e-267 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
PHLHKCMP_00114 2e-19 M Lysin motif
PHLHKCMP_00115 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PHLHKCMP_00116 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
PHLHKCMP_00117 7.9e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PHLHKCMP_00118 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PHLHKCMP_00119 2.7e-217 S Tetratricopeptide repeat protein
PHLHKCMP_00120 3.3e-149 3.1.3.102, 3.1.3.104 S hydrolase
PHLHKCMP_00121 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PHLHKCMP_00122 1e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PHLHKCMP_00123 9.6e-85
PHLHKCMP_00124 0.0 yfmR S ABC transporter, ATP-binding protein
PHLHKCMP_00125 3.9e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PHLHKCMP_00126 1.7e-90 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PHLHKCMP_00127 9.7e-147 DegV S EDD domain protein, DegV family
PHLHKCMP_00128 3.1e-149 ypmR E GDSL-like Lipase/Acylhydrolase
PHLHKCMP_00129 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PHLHKCMP_00130 3.4e-35 yozE S Belongs to the UPF0346 family
PHLHKCMP_00131 8.6e-260 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
PHLHKCMP_00132 4.7e-250 emrY EGP Major facilitator Superfamily
PHLHKCMP_00133 1.4e-195 XK27_00915 C Luciferase-like monooxygenase
PHLHKCMP_00134 7.2e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PHLHKCMP_00135 1.4e-140 EGP Major facilitator Superfamily
PHLHKCMP_00137 1.1e-18 S YopX protein
PHLHKCMP_00140 1.2e-46
PHLHKCMP_00141 1.3e-39 L Helix-turn-helix domain
PHLHKCMP_00143 2.5e-124 S Putative HNHc nuclease
PHLHKCMP_00144 1.4e-71 S Protein of unknown function (DUF669)
PHLHKCMP_00145 6.9e-116 S AAA domain
PHLHKCMP_00146 6.8e-140 S Protein of unknown function (DUF1351)
PHLHKCMP_00151 1.4e-25
PHLHKCMP_00153 2.2e-92 K ORF6N domain
PHLHKCMP_00154 3.7e-12 K Helix-turn-helix XRE-family like proteins
PHLHKCMP_00155 8.3e-249 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PHLHKCMP_00156 1.6e-94 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PHLHKCMP_00157 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PHLHKCMP_00158 3.6e-58 S Protein of unknown function (DUF1516)
PHLHKCMP_00159 3.3e-89 gtcA S Teichoic acid glycosylation protein
PHLHKCMP_00160 2.3e-179
PHLHKCMP_00161 6e-10
PHLHKCMP_00162 2.1e-57
PHLHKCMP_00164 1.5e-09 hol S Bacteriophage holin
PHLHKCMP_00165 6.9e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
PHLHKCMP_00166 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
PHLHKCMP_00167 2.8e-70 K MarR family
PHLHKCMP_00168 3.7e-210 EGP Major facilitator Superfamily
PHLHKCMP_00169 3.8e-85 S membrane transporter protein
PHLHKCMP_00170 2.7e-97 K Bacterial regulatory proteins, tetR family
PHLHKCMP_00171 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PHLHKCMP_00172 2.9e-78 3.6.1.55 F NUDIX domain
PHLHKCMP_00173 1.4e-47 sugE U Multidrug resistance protein
PHLHKCMP_00174 9.9e-26
PHLHKCMP_00175 3.9e-259 pgi 5.3.1.9 G Belongs to the GPI family
PHLHKCMP_00176 6.8e-24
PHLHKCMP_00177 8.4e-175 macB3 V ABC transporter, ATP-binding protein
PHLHKCMP_00178 1e-143 macB3 V ABC transporter, ATP-binding protein
PHLHKCMP_00179 4.9e-269 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
PHLHKCMP_00180 4.9e-302 msbA2 3.6.3.44 P ABC transporter transmembrane region
PHLHKCMP_00181 2.2e-73 3.1.3.102, 3.1.3.104 S hydrolase
PHLHKCMP_00182 0.0 S Predicted membrane protein (DUF2207)
PHLHKCMP_00183 0.0 uvrA3 L excinuclease ABC
PHLHKCMP_00184 1.9e-85 EGP Major facilitator Superfamily
PHLHKCMP_00185 1.4e-89 EGP Major facilitator Superfamily
PHLHKCMP_00186 1.6e-171 ropB K Helix-turn-helix XRE-family like proteins
PHLHKCMP_00187 2.6e-115 K Bacterial regulatory proteins, tetR family
PHLHKCMP_00188 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PHLHKCMP_00189 4.2e-47
PHLHKCMP_00190 1.6e-77 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PHLHKCMP_00191 2.4e-99 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PHLHKCMP_00192 2.6e-18
PHLHKCMP_00193 2.2e-151 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
PHLHKCMP_00194 7.3e-81 K LysR substrate binding domain
PHLHKCMP_00196 2.9e-60 M domain protein
PHLHKCMP_00197 2.4e-130 M domain protein
PHLHKCMP_00198 5.7e-49 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PHLHKCMP_00199 6.9e-57 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PHLHKCMP_00200 4.2e-52 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
PHLHKCMP_00201 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
PHLHKCMP_00202 1.7e-153 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHLHKCMP_00203 2.2e-18 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHLHKCMP_00204 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PHLHKCMP_00205 6.8e-237 rarA L recombination factor protein RarA
PHLHKCMP_00206 2.5e-38
PHLHKCMP_00207 6.2e-82 usp6 T universal stress protein
PHLHKCMP_00208 1.4e-196 bla2 3.5.2.6 V Beta-lactamase enzyme family
PHLHKCMP_00209 6.2e-160 2.3.1.19 K Helix-turn-helix XRE-family like proteins
PHLHKCMP_00210 1.7e-93 L Transposase
PHLHKCMP_00211 6.3e-131 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PHLHKCMP_00212 6.6e-157 yihY S Belongs to the UPF0761 family
PHLHKCMP_00213 4.2e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PHLHKCMP_00214 5.9e-219 pbpX1 V Beta-lactamase
PHLHKCMP_00215 7.6e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PHLHKCMP_00216 5e-64 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_00217 7.9e-179 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PHLHKCMP_00218 8.8e-127 2.4.1.52 GT4 M Glycosyl transferases group 1
PHLHKCMP_00221 3.5e-64
PHLHKCMP_00222 1.4e-74 yugI 5.3.1.9 J general stress protein
PHLHKCMP_00223 2.1e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PHLHKCMP_00224 3e-119 dedA S SNARE-like domain protein
PHLHKCMP_00225 1e-116 S Protein of unknown function (DUF1461)
PHLHKCMP_00226 2.6e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PHLHKCMP_00227 1.5e-80 yutD S Protein of unknown function (DUF1027)
PHLHKCMP_00228 2.7e-73 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PHLHKCMP_00229 2.8e-171 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PHLHKCMP_00230 1.1e-115 S Calcineurin-like phosphoesterase
PHLHKCMP_00231 1.6e-252 cycA E Amino acid permease
PHLHKCMP_00232 1.5e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHLHKCMP_00233 9.4e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
PHLHKCMP_00235 1.3e-87 S Prokaryotic N-terminal methylation motif
PHLHKCMP_00236 1.4e-17
PHLHKCMP_00237 4.4e-71 gspG NU general secretion pathway protein
PHLHKCMP_00238 1.8e-41 comGC U competence protein ComGC
PHLHKCMP_00239 7.3e-144 comGB NU type II secretion system
PHLHKCMP_00240 2e-29 comGB NU type II secretion system
PHLHKCMP_00241 7.8e-115 comGA NU Type II IV secretion system protein
PHLHKCMP_00242 8.8e-34 comGA NU Type II IV secretion system protein
PHLHKCMP_00243 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PHLHKCMP_00244 8.3e-131 yebC K Transcriptional regulatory protein
PHLHKCMP_00245 1.6e-49 S DsrE/DsrF-like family
PHLHKCMP_00246 8.4e-162 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
PHLHKCMP_00247 5.5e-181 ccpA K catabolite control protein A
PHLHKCMP_00248 2.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PHLHKCMP_00249 1.1e-80 K helix_turn_helix, mercury resistance
PHLHKCMP_00250 4e-55
PHLHKCMP_00251 1.6e-33 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PHLHKCMP_00252 9.8e-158 ykuT M mechanosensitive ion channel
PHLHKCMP_00253 1.6e-224 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PHLHKCMP_00254 1.7e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PHLHKCMP_00255 6.5e-87 ykuL S (CBS) domain
PHLHKCMP_00256 4.7e-96 S Phosphoesterase
PHLHKCMP_00257 1.2e-109 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PHLHKCMP_00258 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PHLHKCMP_00259 9.9e-126 yslB S Protein of unknown function (DUF2507)
PHLHKCMP_00260 1.3e-51 trxA O Belongs to the thioredoxin family
PHLHKCMP_00261 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PHLHKCMP_00262 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PHLHKCMP_00263 1.6e-48 yrzB S Belongs to the UPF0473 family
PHLHKCMP_00264 8.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PHLHKCMP_00265 2.4e-43 yrzL S Belongs to the UPF0297 family
PHLHKCMP_00266 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PHLHKCMP_00267 3.9e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PHLHKCMP_00268 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PHLHKCMP_00269 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PHLHKCMP_00270 2.4e-28 yajC U Preprotein translocase
PHLHKCMP_00271 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PHLHKCMP_00272 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PHLHKCMP_00273 2.7e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PHLHKCMP_00274 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PHLHKCMP_00275 1.7e-90
PHLHKCMP_00276 0.0 S Bacterial membrane protein YfhO
PHLHKCMP_00277 1.4e-51
PHLHKCMP_00278 1.6e-115 S Protein of unknown function (DUF554)
PHLHKCMP_00279 1.7e-148 KT helix_turn_helix, mercury resistance
PHLHKCMP_00280 8.5e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PHLHKCMP_00281 6.6e-95 S Protein of unknown function (DUF1440)
PHLHKCMP_00282 1.3e-172 hrtB V ABC transporter permease
PHLHKCMP_00283 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PHLHKCMP_00284 9.2e-90 2.7.7.65 T phosphorelay sensor kinase activity
PHLHKCMP_00285 2.6e-58 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PHLHKCMP_00286 9.5e-119 draG 3.2.2.24 O ADP-ribosylglycohydrolase
PHLHKCMP_00287 8.1e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PHLHKCMP_00288 2e-42
PHLHKCMP_00289 9.9e-82 hit FG histidine triad
PHLHKCMP_00290 1.6e-134 ecsA V ABC transporter, ATP-binding protein
PHLHKCMP_00291 4.8e-224 ecsB U ABC transporter
PHLHKCMP_00292 7.8e-151 ytmP 2.7.1.89 M Choline/ethanolamine kinase
PHLHKCMP_00293 6.3e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PHLHKCMP_00294 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
PHLHKCMP_00295 9.9e-203 xylR GK ROK family
PHLHKCMP_00296 6.2e-167 K AI-2E family transporter
PHLHKCMP_00297 3.3e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHLHKCMP_00298 1e-32
PHLHKCMP_00299 1.9e-36 L the current gene model (or a revised gene model) may contain a frame shift
PHLHKCMP_00300 7.4e-108 iolS C Aldo keto reductase
PHLHKCMP_00301 1.5e-49 yxkA S Phosphatidylethanolamine-binding protein
PHLHKCMP_00302 7.2e-209
PHLHKCMP_00303 2.6e-178 cps4G M Glycosyltransferase Family 4
PHLHKCMP_00304 4.7e-135 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
PHLHKCMP_00305 1.4e-41 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
PHLHKCMP_00306 7.4e-118 tuaA M Bacterial sugar transferase
PHLHKCMP_00307 9.5e-62 cps4D 5.1.3.2 M RmlD substrate binding domain
PHLHKCMP_00308 2.8e-97 cps4D 5.1.3.2 M RmlD substrate binding domain
PHLHKCMP_00309 1.8e-126 ywqE 3.1.3.48 GM PHP domain protein
PHLHKCMP_00310 4.5e-110 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PHLHKCMP_00311 1.5e-71 epsB M biosynthesis protein
PHLHKCMP_00312 2.8e-155 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_00313 1.2e-182 4.1.1.45 E amidohydrolase
PHLHKCMP_00314 9.4e-77
PHLHKCMP_00315 1e-273 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHLHKCMP_00316 5.2e-81 ybbL S ABC transporter, ATP-binding protein
PHLHKCMP_00317 1.3e-20 ybbL S ATPases associated with a variety of cellular activities
PHLHKCMP_00318 2e-37 ybbM S Uncharacterised protein family (UPF0014)
PHLHKCMP_00319 4.4e-62 ybbM S Uncharacterised protein family (UPF0014)
PHLHKCMP_00320 3.8e-204 S DUF218 domain
PHLHKCMP_00321 2e-115 luxT K Bacterial regulatory proteins, tetR family
PHLHKCMP_00322 4.3e-132 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
PHLHKCMP_00323 2.5e-180 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
PHLHKCMP_00324 1.8e-27
PHLHKCMP_00325 5.4e-47 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PHLHKCMP_00326 6.7e-74 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PHLHKCMP_00327 1.3e-116 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PHLHKCMP_00328 8.1e-74 mltD CBM50 M PFAM NLP P60 protein
PHLHKCMP_00329 2.5e-53
PHLHKCMP_00330 4.2e-62
PHLHKCMP_00332 2.3e-176 S Oxidoreductase family, NAD-binding Rossmann fold
PHLHKCMP_00333 1.2e-196 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
PHLHKCMP_00334 0.0 yjcE P Sodium proton antiporter
PHLHKCMP_00335 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PHLHKCMP_00336 3.8e-215 yfjF U Sugar (and other) transporter
PHLHKCMP_00337 3.5e-74 K Bacterial regulatory proteins, tetR family
PHLHKCMP_00338 1.1e-140 fhuD P Periplasmic binding protein
PHLHKCMP_00339 6.1e-111 fhuC 3.6.3.34 HP ABC transporter
PHLHKCMP_00340 2.4e-136 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PHLHKCMP_00341 1.4e-133 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PHLHKCMP_00342 6.9e-246 lmrB EGP Major facilitator Superfamily
PHLHKCMP_00343 5.9e-73 S COG NOG18757 non supervised orthologous group
PHLHKCMP_00344 3.7e-39
PHLHKCMP_00345 4.7e-73 copR K Copper transport repressor CopY TcrY
PHLHKCMP_00346 0.0 copB 3.6.3.4 P P-type ATPase
PHLHKCMP_00347 2.8e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PHLHKCMP_00349 2.8e-134 yvdE K helix_turn _helix lactose operon repressor
PHLHKCMP_00350 2.9e-26 yvdE K helix_turn _helix lactose operon repressor
PHLHKCMP_00351 6.5e-190 malR K Transcriptional regulator, LacI family
PHLHKCMP_00352 2.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PHLHKCMP_00353 2.6e-56 dhaM 2.7.1.121 S PTS system fructose IIA component
PHLHKCMP_00354 7.9e-100 dhaL 2.7.1.121 S Dak2
PHLHKCMP_00355 4.3e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PHLHKCMP_00356 3.1e-189 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PHLHKCMP_00357 8.7e-90 K Bacterial regulatory proteins, tetR family
PHLHKCMP_00358 5.7e-155 mccF 3.4.17.13 V LD-carboxypeptidase
PHLHKCMP_00359 1.1e-72 XK27_05710 K Acetyltransferase (GNAT) domain
PHLHKCMP_00360 7.9e-124
PHLHKCMP_00361 1e-119 3.6.3.35 P ATPases associated with a variety of cellular activities
PHLHKCMP_00362 1.5e-189
PHLHKCMP_00363 1.5e-146 S hydrolase activity, acting on ester bonds
PHLHKCMP_00364 4.7e-210 yurR 1.4.5.1 E FAD dependent oxidoreductase
PHLHKCMP_00365 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
PHLHKCMP_00366 3.3e-62 esbA S Family of unknown function (DUF5322)
PHLHKCMP_00367 2.5e-292 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PHLHKCMP_00368 4.1e-72 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PHLHKCMP_00369 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PHLHKCMP_00370 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHLHKCMP_00371 1.8e-206 carA 6.3.5.5 F Belongs to the CarA family
PHLHKCMP_00372 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PHLHKCMP_00373 6e-111 pgm5 G Phosphoglycerate mutase family
PHLHKCMP_00374 1.7e-69 frataxin S Domain of unknown function (DU1801)
PHLHKCMP_00376 9.3e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
PHLHKCMP_00377 3.5e-69 S LuxR family transcriptional regulator
PHLHKCMP_00378 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
PHLHKCMP_00380 6.3e-90 3.6.1.55 F NUDIX domain
PHLHKCMP_00381 6.8e-30 V ABC transporter, ATP-binding protein
PHLHKCMP_00382 2.2e-91 V ABC transporter, ATP-binding protein
PHLHKCMP_00383 2.6e-43 S ABC-2 family transporter protein
PHLHKCMP_00384 1.4e-75 S ABC-2 family transporter protein
PHLHKCMP_00385 0.0 FbpA K Fibronectin-binding protein
PHLHKCMP_00386 2.7e-65 K Transcriptional regulator
PHLHKCMP_00387 3.5e-160 degV S EDD domain protein, DegV family
PHLHKCMP_00388 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
PHLHKCMP_00389 7.1e-130 S Protein of unknown function (DUF975)
PHLHKCMP_00390 1.7e-09
PHLHKCMP_00391 1.5e-49
PHLHKCMP_00392 8.1e-148 2.7.7.12 C Domain of unknown function (DUF4931)
PHLHKCMP_00393 2.6e-206 pmrB EGP Major facilitator Superfamily
PHLHKCMP_00394 3.6e-12
PHLHKCMP_00395 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
PHLHKCMP_00396 4.6e-129 yejC S Protein of unknown function (DUF1003)
PHLHKCMP_00397 2.8e-133 XK27_00890 S Domain of unknown function (DUF368)
PHLHKCMP_00398 1.8e-243 cycA E Amino acid permease
PHLHKCMP_00399 6.5e-114
PHLHKCMP_00400 4.1e-59
PHLHKCMP_00401 1.1e-182 lldP C L-lactate permease
PHLHKCMP_00402 1.4e-79 lldP C L-lactate permease
PHLHKCMP_00403 1.7e-225
PHLHKCMP_00404 9.9e-115 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
PHLHKCMP_00405 4e-187 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
PHLHKCMP_00406 2.9e-199 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHLHKCMP_00407 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHLHKCMP_00408 8.5e-93 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PHLHKCMP_00409 4.9e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
PHLHKCMP_00410 9e-240 gshR1 1.8.1.7 C Glutathione reductase
PHLHKCMP_00411 2.7e-49
PHLHKCMP_00412 1.5e-137 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PHLHKCMP_00413 9.5e-20 yhaI J Protein of unknown function (DUF805)
PHLHKCMP_00416 2.6e-64
PHLHKCMP_00417 4.3e-30 L the current gene model (or a revised gene model) may contain a frame shift
PHLHKCMP_00418 5.4e-30 tnp L DDE domain
PHLHKCMP_00419 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PHLHKCMP_00420 4.7e-102 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
PHLHKCMP_00421 1.1e-07 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
PHLHKCMP_00422 7.9e-41
PHLHKCMP_00423 1.9e-67 tspO T TspO/MBR family
PHLHKCMP_00424 6.3e-76 uspA T Belongs to the universal stress protein A family
PHLHKCMP_00425 8e-66 S Protein of unknown function (DUF805)
PHLHKCMP_00426 3e-162 yegS I Diacylglycerol kinase catalytic domain
PHLHKCMP_00427 8.2e-85
PHLHKCMP_00428 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PHLHKCMP_00429 3.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PHLHKCMP_00430 2.9e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PHLHKCMP_00431 4.4e-207 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PHLHKCMP_00432 7.7e-266 lpdA 1.8.1.4 C Dehydrogenase
PHLHKCMP_00433 2.5e-125 hoxN U High-affinity nickel-transport protein
PHLHKCMP_00434 5.6e-120 L PFAM Integrase catalytic region
PHLHKCMP_00435 3e-45 L Helix-turn-helix domain
PHLHKCMP_00436 1.2e-110 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PHLHKCMP_00437 1.9e-91 larE S NAD synthase
PHLHKCMP_00438 1.3e-62 larC 4.99.1.12 S Protein of unknown function DUF111
PHLHKCMP_00439 3.6e-38 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PHLHKCMP_00440 2e-81 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
PHLHKCMP_00441 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_00442 5.3e-16 L 4.5 Transposon and IS
PHLHKCMP_00443 1.6e-28 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_00445 1.8e-84 hmpT S Pfam:DUF3816
PHLHKCMP_00446 3.8e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PHLHKCMP_00447 4.8e-109
PHLHKCMP_00448 2.3e-155 M Glycosyl hydrolases family 25
PHLHKCMP_00449 2.2e-142 yvpB S Peptidase_C39 like family
PHLHKCMP_00450 3.8e-309 oppA E ABC transporter, substratebinding protein
PHLHKCMP_00451 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHLHKCMP_00452 5.6e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHLHKCMP_00453 6e-202 oppD P Belongs to the ABC transporter superfamily
PHLHKCMP_00454 3.4e-180 oppF P Belongs to the ABC transporter superfamily
PHLHKCMP_00455 1.1e-95 rmaB K Transcriptional regulator, MarR family
PHLHKCMP_00456 0.0 lmrA 3.6.3.44 V ABC transporter
PHLHKCMP_00457 6.1e-160 ypbG 2.7.1.2 GK ROK family
PHLHKCMP_00458 3.5e-12
PHLHKCMP_00462 6.4e-14 S Short repeat of unknown function (DUF308)
PHLHKCMP_00465 2.1e-19 S Short repeat of unknown function (DUF308)
PHLHKCMP_00467 2.7e-20 hsp O Belongs to the small heat shock protein (HSP20) family
PHLHKCMP_00468 5.8e-09
PHLHKCMP_00469 1.6e-53
PHLHKCMP_00470 1.9e-38
PHLHKCMP_00471 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PHLHKCMP_00472 1.1e-193 uhpT EGP Major facilitator Superfamily
PHLHKCMP_00473 3.8e-145 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
PHLHKCMP_00474 7.3e-166 K Transcriptional regulator
PHLHKCMP_00475 1.5e-149 S hydrolase
PHLHKCMP_00476 1.2e-225 pbuG S permease
PHLHKCMP_00477 1.5e-19
PHLHKCMP_00478 3.6e-82 K Transcriptional regulator
PHLHKCMP_00479 8e-151 licD M LicD family
PHLHKCMP_00480 4.1e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PHLHKCMP_00481 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PHLHKCMP_00482 9.4e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PHLHKCMP_00483 1.1e-240 EGP Major facilitator Superfamily
PHLHKCMP_00484 6.2e-12 V VanZ like family
PHLHKCMP_00485 5.2e-56 V VanZ like family
PHLHKCMP_00486 1.5e-33
PHLHKCMP_00487 1.9e-71 spxA 1.20.4.1 P ArsC family
PHLHKCMP_00489 8.8e-119
PHLHKCMP_00490 5.9e-296 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PHLHKCMP_00491 4.7e-95 G Transmembrane secretion effector
PHLHKCMP_00492 4.5e-62 EGP Transmembrane secretion effector
PHLHKCMP_00493 1.5e-130 1.5.1.39 C nitroreductase
PHLHKCMP_00494 5.7e-71
PHLHKCMP_00495 1.5e-52
PHLHKCMP_00496 1.3e-206 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PHLHKCMP_00497 3.1e-104 K Bacterial regulatory proteins, tetR family
PHLHKCMP_00498 3.2e-147 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
PHLHKCMP_00499 4.5e-123 yliE T EAL domain
PHLHKCMP_00500 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PHLHKCMP_00501 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PHLHKCMP_00502 3.5e-124 ybbR S YbbR-like protein
PHLHKCMP_00503 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PHLHKCMP_00504 7.1e-121 S Protein of unknown function (DUF1361)
PHLHKCMP_00505 3.8e-90 K helix_turn_helix multiple antibiotic resistance protein
PHLHKCMP_00506 0.0 yjcE P Sodium proton antiporter
PHLHKCMP_00507 1.8e-167 murB 1.3.1.98 M Cell wall formation
PHLHKCMP_00508 9.9e-158 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
PHLHKCMP_00509 7.7e-154 xth 3.1.11.2 L exodeoxyribonuclease III
PHLHKCMP_00510 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
PHLHKCMP_00511 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
PHLHKCMP_00512 3.2e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PHLHKCMP_00513 4.6e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PHLHKCMP_00514 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PHLHKCMP_00515 9.9e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
PHLHKCMP_00516 1.4e-104 yxjI
PHLHKCMP_00517 1.3e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PHLHKCMP_00518 4.8e-255 glnP P ABC transporter
PHLHKCMP_00519 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
PHLHKCMP_00520 1.6e-15 3.4.21.72 M Bacterial Ig-like domain (group 3)
PHLHKCMP_00521 7.9e-168 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
PHLHKCMP_00522 8.5e-139 S Belongs to the UPF0246 family
PHLHKCMP_00523 3.8e-31
PHLHKCMP_00524 2.9e-301 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
PHLHKCMP_00525 1.6e-16
PHLHKCMP_00526 1.6e-105
PHLHKCMP_00527 5.7e-10
PHLHKCMP_00528 3.9e-101 S WxL domain surface cell wall-binding
PHLHKCMP_00529 4.7e-109 S Cell surface protein
PHLHKCMP_00530 1.6e-67 S Cell surface protein
PHLHKCMP_00531 1.3e-75
PHLHKCMP_00532 4.6e-96
PHLHKCMP_00533 1e-94
PHLHKCMP_00534 6.9e-76 hpk9 2.7.13.3 T GHKL domain
PHLHKCMP_00535 1.4e-125 hpk9 2.7.13.3 T GHKL domain
PHLHKCMP_00536 3.4e-36 S TfoX C-terminal domain
PHLHKCMP_00537 7.6e-161 1.1.1.27 C L-malate dehydrogenase activity
PHLHKCMP_00538 2.8e-45 yktA S Belongs to the UPF0223 family
PHLHKCMP_00539 1.3e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PHLHKCMP_00540 0.0 typA T GTP-binding protein TypA
PHLHKCMP_00541 5.8e-135
PHLHKCMP_00542 2.6e-108
PHLHKCMP_00543 9.1e-54
PHLHKCMP_00544 1.3e-58
PHLHKCMP_00545 1.5e-179 S Cell surface protein
PHLHKCMP_00546 4.5e-140 livM E Branched-chain amino acid transport system / permease component
PHLHKCMP_00547 4e-126 livH U Branched-chain amino acid transport system / permease component
PHLHKCMP_00548 4.2e-113 livJ E Receptor family ligand binding region
PHLHKCMP_00549 1.7e-300 ydgH S MMPL family
PHLHKCMP_00550 7.1e-112 S Protein of unknown function (DUF1211)
PHLHKCMP_00551 3.7e-34
PHLHKCMP_00552 1e-184 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PHLHKCMP_00553 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PHLHKCMP_00554 5.1e-12 rmeB K transcriptional regulator, MerR family
PHLHKCMP_00556 5.1e-96
PHLHKCMP_00557 4e-122 psaA P Belongs to the bacterial solute-binding protein 9 family
PHLHKCMP_00558 3.3e-78 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PHLHKCMP_00560 9.5e-32 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PHLHKCMP_00561 6.7e-11 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PHLHKCMP_00563 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
PHLHKCMP_00565 4e-201 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PHLHKCMP_00566 1.8e-144 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PHLHKCMP_00567 6.5e-16 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PHLHKCMP_00568 6.6e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PHLHKCMP_00569 8.9e-161 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
PHLHKCMP_00570 1.3e-213 ysaA V RDD family
PHLHKCMP_00571 7.6e-166 corA P CorA-like Mg2+ transporter protein
PHLHKCMP_00572 7.7e-50 S Domain of unknown function (DU1801)
PHLHKCMP_00573 1.9e-159 ccpB 5.1.1.1 K lacI family
PHLHKCMP_00574 5.8e-141 yceE S haloacid dehalogenase-like hydrolase
PHLHKCMP_00575 2.3e-119 drgA C Nitroreductase family
PHLHKCMP_00576 1.6e-77 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
PHLHKCMP_00577 3.4e-253 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
PHLHKCMP_00580 1.2e-33 L Phage integrase family
PHLHKCMP_00581 5.1e-163 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PHLHKCMP_00582 3.2e-26
PHLHKCMP_00583 2.3e-15
PHLHKCMP_00584 1.7e-212 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PHLHKCMP_00585 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PHLHKCMP_00586 1e-176 S Protein of unknown function (DUF2785)
PHLHKCMP_00587 8.2e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
PHLHKCMP_00588 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
PHLHKCMP_00589 1.4e-111 metI U ABC transporter permease
PHLHKCMP_00590 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHLHKCMP_00591 3.6e-48 gcsH2 E glycine cleavage
PHLHKCMP_00592 9.3e-220 rodA D Belongs to the SEDS family
PHLHKCMP_00593 3.3e-33 S Protein of unknown function (DUF2969)
PHLHKCMP_00594 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PHLHKCMP_00595 2.7e-180 mbl D Cell shape determining protein MreB Mrl
PHLHKCMP_00596 7.6e-100 J Acetyltransferase (GNAT) domain
PHLHKCMP_00597 6.3e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHLHKCMP_00598 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PHLHKCMP_00599 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PHLHKCMP_00600 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PHLHKCMP_00601 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PHLHKCMP_00602 8.5e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHLHKCMP_00603 2.1e-35 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PHLHKCMP_00604 1.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHLHKCMP_00605 3.8e-104 atpB C it plays a direct role in the translocation of protons across the membrane
PHLHKCMP_00606 8.6e-224 pyrP F Permease
PHLHKCMP_00607 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PHLHKCMP_00608 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PHLHKCMP_00609 1.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PHLHKCMP_00610 2.1e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PHLHKCMP_00611 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PHLHKCMP_00612 2e-106 tdk 2.7.1.21 F thymidine kinase
PHLHKCMP_00613 9.9e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
PHLHKCMP_00614 5.9e-137 cobQ S glutamine amidotransferase
PHLHKCMP_00615 1.8e-194 manA 5.3.1.8 G mannose-6-phosphate isomerase
PHLHKCMP_00616 6.5e-190 ampC V Beta-lactamase
PHLHKCMP_00617 5.2e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PHLHKCMP_00618 1.9e-58
PHLHKCMP_00619 1.8e-125
PHLHKCMP_00620 0.0 yfiC V ABC transporter
PHLHKCMP_00621 2.4e-311 ycfI V ABC transporter, ATP-binding protein
PHLHKCMP_00622 9.5e-65 S Protein of unknown function (DUF1093)
PHLHKCMP_00623 3.8e-135 yxkH G Polysaccharide deacetylase
PHLHKCMP_00627 3.3e-10 S Haemolysin XhlA
PHLHKCMP_00628 2.1e-85 M hydrolase, family 25
PHLHKCMP_00630 2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHLHKCMP_00631 1e-69
PHLHKCMP_00632 5.2e-30 ygzD K Transcriptional
PHLHKCMP_00633 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PHLHKCMP_00634 7.7e-174 P Major Facilitator Superfamily
PHLHKCMP_00635 1.2e-221 1.3.5.4 C FAD dependent oxidoreductase
PHLHKCMP_00636 2.4e-66 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
PHLHKCMP_00637 5.7e-16
PHLHKCMP_00638 7.2e-223 2.7.13.3 T GHKL domain
PHLHKCMP_00639 1.7e-134 K LytTr DNA-binding domain
PHLHKCMP_00640 2.4e-77 yneH 1.20.4.1 K ArsC family
PHLHKCMP_00641 1e-223 katA 1.11.1.6 C Belongs to the catalase family
PHLHKCMP_00642 5.4e-46 katA 1.11.1.6 C Belongs to the catalase family
PHLHKCMP_00643 3.7e-88 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PHLHKCMP_00644 1.3e-120 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PHLHKCMP_00645 1.2e-18 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PHLHKCMP_00646 1.6e-73 K helix_turn_helix multiple antibiotic resistance protein
PHLHKCMP_00647 1.6e-263 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PHLHKCMP_00648 1.2e-88 MA20_25245 K FR47-like protein
PHLHKCMP_00649 7.5e-126 hchA S DJ-1/PfpI family
PHLHKCMP_00650 2.1e-174 1.1.1.1 C nadph quinone reductase
PHLHKCMP_00651 1.9e-47 K helix_turn_helix, Arsenical Resistance Operon Repressor
PHLHKCMP_00652 1.1e-93 mepA V MATE efflux family protein
PHLHKCMP_00653 2.5e-108 mepA V MATE efflux family protein
PHLHKCMP_00654 6e-90 pva1 3.5.1.24 M Choloylglycine hydrolase
PHLHKCMP_00655 7.7e-218 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PHLHKCMP_00656 2e-65 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_00657 1.5e-161 P Natural resistance-associated macrophage protein
PHLHKCMP_00658 4.6e-157 xerD L Phage integrase, N-terminal SAM-like domain
PHLHKCMP_00659 4.2e-32 S YozE SAM-like fold
PHLHKCMP_00660 9.8e-94 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHLHKCMP_00661 2.6e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PHLHKCMP_00662 1.4e-167 ppaC 3.6.1.1 C inorganic pyrophosphatase
PHLHKCMP_00663 1.6e-177 K Transcriptional regulator
PHLHKCMP_00664 9.8e-228 tdcC E amino acid
PHLHKCMP_00665 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PHLHKCMP_00666 4.9e-157 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PHLHKCMP_00667 9.8e-132 S YheO-like PAS domain
PHLHKCMP_00668 1.5e-144 IQ NAD dependent epimerase/dehydratase family
PHLHKCMP_00669 1.4e-159 rbsU U ribose uptake protein RbsU
PHLHKCMP_00670 9.4e-36 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PHLHKCMP_00671 7.6e-21 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PHLHKCMP_00672 5.7e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PHLHKCMP_00673 9.5e-186 rbsR K helix_turn _helix lactose operon repressor
PHLHKCMP_00675 3e-83 wzb 3.1.3.48 T Tyrosine phosphatase family
PHLHKCMP_00678 1.7e-42 L the current gene model (or a revised gene model) may contain a frame shift
PHLHKCMP_00679 2.1e-19 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_00680 3.4e-109 desK 2.7.13.3 T Histidine kinase
PHLHKCMP_00681 1e-131 yvfS V ABC-2 type transporter
PHLHKCMP_00682 2e-155 yvfR V ABC transporter
PHLHKCMP_00683 1.3e-81 K Acetyltransferase (GNAT) domain
PHLHKCMP_00684 1.5e-77 K MarR family
PHLHKCMP_00685 4.7e-112 S Psort location CytoplasmicMembrane, score
PHLHKCMP_00686 5.4e-74 ydaN S Bacterial cellulose synthase subunit
PHLHKCMP_00687 1.7e-215 ydaN S Bacterial cellulose synthase subunit
PHLHKCMP_00688 4e-132 2.7.7.65 T diguanylate cyclase activity
PHLHKCMP_00689 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PHLHKCMP_00690 2e-109 yviA S Protein of unknown function (DUF421)
PHLHKCMP_00691 1.1e-61 S Protein of unknown function (DUF3290)
PHLHKCMP_00692 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PHLHKCMP_00693 1.1e-130 yliE T Putative diguanylate phosphodiesterase
PHLHKCMP_00694 4e-87 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PHLHKCMP_00695 6.5e-159 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PHLHKCMP_00696 1.1e-101 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PHLHKCMP_00697 3.5e-211 norA EGP Major facilitator Superfamily
PHLHKCMP_00698 1.2e-117 yfbR S HD containing hydrolase-like enzyme
PHLHKCMP_00699 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PHLHKCMP_00700 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PHLHKCMP_00701 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PHLHKCMP_00702 1.2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PHLHKCMP_00703 5.5e-264 argH 4.3.2.1 E argininosuccinate lyase
PHLHKCMP_00704 9.3e-87 S Short repeat of unknown function (DUF308)
PHLHKCMP_00705 1.1e-161 rapZ S Displays ATPase and GTPase activities
PHLHKCMP_00706 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PHLHKCMP_00707 2.7e-166 whiA K May be required for sporulation
PHLHKCMP_00708 2.6e-305 oppA E ABC transporter, substratebinding protein
PHLHKCMP_00709 1.6e-174 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHLHKCMP_00710 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PHLHKCMP_00712 1.3e-243 rpoN K Sigma-54 factor, core binding domain
PHLHKCMP_00713 6.8e-187 cggR K Putative sugar-binding domain
PHLHKCMP_00714 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PHLHKCMP_00715 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PHLHKCMP_00716 4.7e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PHLHKCMP_00717 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHLHKCMP_00718 4.8e-133
PHLHKCMP_00719 4.3e-294 clcA P chloride
PHLHKCMP_00720 1.2e-30 secG U Preprotein translocase
PHLHKCMP_00721 3.6e-137 est 3.1.1.1 S Serine aminopeptidase, S33
PHLHKCMP_00722 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PHLHKCMP_00723 1.8e-81 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PHLHKCMP_00725 0.0 1.3.5.4 C FMN_bind
PHLHKCMP_00726 9.5e-172 K Transcriptional regulator
PHLHKCMP_00727 1.7e-96 K Helix-turn-helix domain
PHLHKCMP_00728 1.3e-69 K sequence-specific DNA binding
PHLHKCMP_00729 3e-22 L PFAM Integrase catalytic region
PHLHKCMP_00730 3e-24 S Protein of unknown function (DUF1211)
PHLHKCMP_00731 8.3e-61 S Protein of unknown function (DUF1211)
PHLHKCMP_00732 2.9e-116 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
PHLHKCMP_00733 8.7e-43
PHLHKCMP_00734 5.9e-15
PHLHKCMP_00735 1.2e-115 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PHLHKCMP_00736 1.2e-227 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
PHLHKCMP_00737 2.3e-68 S Pyrimidine dimer DNA glycosylase
PHLHKCMP_00738 2.1e-86 folT 2.7.13.3 T ECF transporter, substrate-specific component
PHLHKCMP_00739 3.6e-11
PHLHKCMP_00740 9e-13 ytgB S Transglycosylase associated protein
PHLHKCMP_00743 1.3e-77 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
PHLHKCMP_00745 2.1e-112 cps3D
PHLHKCMP_00746 3.7e-303
PHLHKCMP_00747 1.1e-50 gtcA S Teichoic acid glycosylation protein
PHLHKCMP_00748 2e-126 glf 5.4.99.9 M UDP-galactopyranose mutase
PHLHKCMP_00750 2.8e-53
PHLHKCMP_00751 1e-50 S Phage tail protein
PHLHKCMP_00752 2.9e-71 3.5.1.28 M Glycosyl hydrolases family 25
PHLHKCMP_00753 5.2e-101 lys M Glycosyl hydrolases family 25
PHLHKCMP_00754 2.8e-36 S Haemolysin XhlA
PHLHKCMP_00758 5.5e-27
PHLHKCMP_00759 3.3e-35 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
PHLHKCMP_00762 1.1e-55
PHLHKCMP_00764 5.4e-155 int L Belongs to the 'phage' integrase family
PHLHKCMP_00765 1.6e-76
PHLHKCMP_00767 1e-39 S Phage minor structural protein
PHLHKCMP_00768 2.4e-14 S Phage minor structural protein
PHLHKCMP_00770 1.9e-19
PHLHKCMP_00771 3.5e-60 S ORF6C domain
PHLHKCMP_00781 8.5e-49 L DnaD domain protein
PHLHKCMP_00783 3.5e-75 L Phage integrase, N-terminal SAM-like domain
PHLHKCMP_00784 1.2e-139 f42a O Band 7 protein
PHLHKCMP_00785 6.1e-302 norB EGP Major Facilitator
PHLHKCMP_00786 6.8e-93 K transcriptional regulator
PHLHKCMP_00787 3.1e-187 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PHLHKCMP_00788 4.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
PHLHKCMP_00789 2.4e-156 K LysR substrate binding domain
PHLHKCMP_00790 1e-111 S Protein of unknown function (DUF554)
PHLHKCMP_00791 2.7e-97 2.7.8.7 H Belongs to the P-Pant transferase superfamily
PHLHKCMP_00792 3.4e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PHLHKCMP_00793 8.8e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PHLHKCMP_00794 1.7e-156 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PHLHKCMP_00795 2e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PHLHKCMP_00796 1.8e-69 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
PHLHKCMP_00797 1.7e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PHLHKCMP_00798 5.2e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PHLHKCMP_00799 1.2e-124 IQ reductase
PHLHKCMP_00800 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PHLHKCMP_00801 1.3e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHLHKCMP_00802 1.3e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PHLHKCMP_00803 3.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PHLHKCMP_00804 1.4e-176 yneE K Transcriptional regulator
PHLHKCMP_00805 5.6e-144 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PHLHKCMP_00807 1.4e-57 S Protein of unknown function (DUF1648)
PHLHKCMP_00808 1e-198 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PHLHKCMP_00809 1.5e-132 1.6.5.5 C Zinc-binding dehydrogenase
PHLHKCMP_00810 2.4e-95 entB 3.5.1.19 Q Isochorismatase family
PHLHKCMP_00811 2.1e-135 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PHLHKCMP_00812 2.2e-218 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PHLHKCMP_00813 1.1e-94 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
PHLHKCMP_00814 2.8e-124 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PHLHKCMP_00815 1.4e-163 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PHLHKCMP_00816 2.6e-103 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
PHLHKCMP_00817 3.3e-264 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
PHLHKCMP_00819 1.2e-270 XK27_00765
PHLHKCMP_00820 2e-135 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
PHLHKCMP_00821 2.6e-85
PHLHKCMP_00822 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
PHLHKCMP_00823 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
PHLHKCMP_00824 4.1e-108 pelX UW LPXTG-motif cell wall anchor domain protein
PHLHKCMP_00825 3.2e-15 pelX UW LPXTG-motif cell wall anchor domain protein
PHLHKCMP_00826 8.6e-252 dtpT U amino acid peptide transporter
PHLHKCMP_00827 1.4e-149 yjjH S Calcineurin-like phosphoesterase
PHLHKCMP_00830 1.3e-178 sip L Belongs to the 'phage' integrase family
PHLHKCMP_00831 1.2e-49 S Alpha/beta hydrolase of unknown function (DUF915)
PHLHKCMP_00832 0.0 S membrane
PHLHKCMP_00833 4.3e-35 L Belongs to the 'phage' integrase family
PHLHKCMP_00838 2e-22
PHLHKCMP_00839 3.3e-08
PHLHKCMP_00840 1.1e-54 ypaA S Protein of unknown function (DUF1304)
PHLHKCMP_00841 1.3e-308 mco Q Multicopper oxidase
PHLHKCMP_00842 1.4e-119 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PHLHKCMP_00843 1.7e-21 zmp1 O Zinc-dependent metalloprotease
PHLHKCMP_00844 8e-51 zmp1 O Zinc-dependent metalloprotease
PHLHKCMP_00845 7e-182 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_00846 9.2e-239 S Neutral/alkaline non-lysosomal ceramidase, N-terminal
PHLHKCMP_00847 9.7e-233
PHLHKCMP_00848 2.7e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PHLHKCMP_00849 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PHLHKCMP_00850 3.5e-31
PHLHKCMP_00851 1.1e-42 ankB S ankyrin repeats
PHLHKCMP_00852 2.1e-31 L 4.5 Transposon and IS
PHLHKCMP_00853 1.9e-115 K rpiR family
PHLHKCMP_00854 2.6e-248 fruA 2.7.1.202 G Phosphotransferase System
PHLHKCMP_00855 1.2e-107 cmpC S ATPases associated with a variety of cellular activities
PHLHKCMP_00856 7.6e-151 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
PHLHKCMP_00857 5.1e-168 XK27_00670 S ABC transporter
PHLHKCMP_00858 3.2e-65
PHLHKCMP_00859 3.5e-96 G Glycosyl hydrolases family 8
PHLHKCMP_00860 7.1e-181 ydaM M Glycosyl transferase family group 2
PHLHKCMP_00861 2.6e-46
PHLHKCMP_00862 5.5e-72 S Membrane
PHLHKCMP_00863 2.6e-187 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PHLHKCMP_00864 2.6e-97 1.5.1.3 H RibD C-terminal domain
PHLHKCMP_00865 4.3e-112 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PHLHKCMP_00866 3.6e-155 mleP3 S Membrane transport protein
PHLHKCMP_00867 3.3e-253 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
PHLHKCMP_00868 7.6e-190 ynfM EGP Major facilitator Superfamily
PHLHKCMP_00869 5.1e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PHLHKCMP_00870 3.2e-270 lmrB EGP Major facilitator Superfamily
PHLHKCMP_00871 7.6e-75 S Domain of unknown function (DUF4811)
PHLHKCMP_00872 3.2e-98 rimL J Acetyltransferase (GNAT) domain
PHLHKCMP_00873 4.6e-172 S Conserved hypothetical protein 698
PHLHKCMP_00874 3.1e-150 rlrG K Transcriptional regulator
PHLHKCMP_00875 1.2e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
PHLHKCMP_00876 6.4e-266 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
PHLHKCMP_00878 1e-46 lytE M LysM domain
PHLHKCMP_00879 1.5e-91 ogt 2.1.1.63 L Methyltransferase
PHLHKCMP_00881 6.8e-167 natA S ABC transporter, ATP-binding protein
PHLHKCMP_00882 1.4e-210 natB CP ABC-2 family transporter protein
PHLHKCMP_00883 6.7e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PHLHKCMP_00884 2.5e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
PHLHKCMP_00885 4.2e-76 yphH S Cupin domain
PHLHKCMP_00886 4.4e-79 K transcriptional regulator, MerR family
PHLHKCMP_00887 2.8e-235 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PHLHKCMP_00888 4.6e-244 ylbB V ABC transporter permease
PHLHKCMP_00889 5.9e-203 ylbB V ABC transporter permease
PHLHKCMP_00890 1.4e-119 macB V ABC transporter, ATP-binding protein
PHLHKCMP_00893 1e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PHLHKCMP_00894 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PHLHKCMP_00895 1.1e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PHLHKCMP_00896 1.8e-87 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PHLHKCMP_00897 1.8e-81
PHLHKCMP_00898 1.9e-86 yvbK 3.1.3.25 K GNAT family
PHLHKCMP_00899 7e-37
PHLHKCMP_00900 8.2e-48
PHLHKCMP_00901 4.4e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
PHLHKCMP_00902 5.3e-34 S Domain of unknown function (DUF4440)
PHLHKCMP_00903 2.4e-156 K LysR substrate binding domain
PHLHKCMP_00904 5.4e-104 GM NAD(P)H-binding
PHLHKCMP_00905 8.1e-103 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PHLHKCMP_00906 9.9e-55 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PHLHKCMP_00907 1.8e-148 IQ Enoyl-(Acyl carrier protein) reductase
PHLHKCMP_00908 1.3e-34
PHLHKCMP_00909 6.1e-76 T Belongs to the universal stress protein A family
PHLHKCMP_00910 4.9e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
PHLHKCMP_00911 1.1e-121 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PHLHKCMP_00912 3.2e-92
PHLHKCMP_00913 1.4e-21 K Transcriptional regulator
PHLHKCMP_00914 9e-08 V HNH endonuclease
PHLHKCMP_00915 2.4e-38 L AAA ATPase domain
PHLHKCMP_00916 2.3e-240 amtB P ammonium transporter
PHLHKCMP_00917 5.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PHLHKCMP_00918 1.9e-43
PHLHKCMP_00919 7e-178 citR K sugar-binding domain protein
PHLHKCMP_00920 6.9e-50 citP P Sodium:sulfate symporter transmembrane region
PHLHKCMP_00921 2.2e-194 citP P Sodium:sulfate symporter transmembrane region
PHLHKCMP_00922 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PHLHKCMP_00923 0.0 P Concanavalin A-like lectin/glucanases superfamily
PHLHKCMP_00924 2e-192 ydaM M Glycosyl transferase family group 2
PHLHKCMP_00925 7.6e-206 S Protein conserved in bacteria
PHLHKCMP_00926 7.3e-37
PHLHKCMP_00927 5.7e-38 S MORN repeat
PHLHKCMP_00929 4.6e-96 S Cysteine-rich secretory protein family
PHLHKCMP_00930 5.9e-32
PHLHKCMP_00931 3.5e-114 zmp3 O Zinc-dependent metalloprotease
PHLHKCMP_00932 2.8e-82 gtrA S GtrA-like protein
PHLHKCMP_00933 2.2e-32 K Helix-turn-helix XRE-family like proteins
PHLHKCMP_00934 2.6e-77 K Helix-turn-helix XRE-family like proteins
PHLHKCMP_00935 7.9e-78 K Transcriptional regulator PadR-like family
PHLHKCMP_00936 2.9e-27 EGP Major Facilitator Superfamily
PHLHKCMP_00937 3.1e-59 EGP Major Facilitator Superfamily
PHLHKCMP_00938 2.1e-75 EGP Major Facilitator Superfamily
PHLHKCMP_00939 7.5e-46 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_00940 2.3e-19 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PHLHKCMP_00941 5.8e-152 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PHLHKCMP_00942 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PHLHKCMP_00943 1.2e-231 M hydrolase, family 25
PHLHKCMP_00944 3.9e-76 K Acetyltransferase (GNAT) domain
PHLHKCMP_00945 5.8e-205 mccF V LD-carboxypeptidase
PHLHKCMP_00946 2.1e-188 M Glycosyltransferase, group 2 family protein
PHLHKCMP_00947 2.1e-12 M Glycosyltransferase like family 2
PHLHKCMP_00948 1.2e-73 S SnoaL-like domain
PHLHKCMP_00949 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
PHLHKCMP_00950 1.2e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PHLHKCMP_00952 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PHLHKCMP_00953 8.3e-110 ypsA S Belongs to the UPF0398 family
PHLHKCMP_00954 5e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PHLHKCMP_00955 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PHLHKCMP_00956 8.5e-44 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
PHLHKCMP_00957 1.5e-86 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
PHLHKCMP_00958 1.9e-167 ftpB P Bacterial extracellular solute-binding protein
PHLHKCMP_00959 4.6e-261 ftpA P Binding-protein-dependent transport system inner membrane component
PHLHKCMP_00960 1.4e-81 uspA T Universal stress protein family
PHLHKCMP_00961 2.9e-57 metQ_4 P Belongs to the nlpA lipoprotein family
PHLHKCMP_00962 9.3e-89 metQ_4 P Belongs to the nlpA lipoprotein family
PHLHKCMP_00963 2.9e-98 metI P ABC transporter permease
PHLHKCMP_00964 4.9e-12 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHLHKCMP_00965 1.6e-153 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHLHKCMP_00966 1.3e-128 dnaD L Replication initiation and membrane attachment
PHLHKCMP_00967 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PHLHKCMP_00968 4.3e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PHLHKCMP_00969 1e-71 ypmB S protein conserved in bacteria
PHLHKCMP_00970 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PHLHKCMP_00971 7.6e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PHLHKCMP_00972 1.3e-171 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PHLHKCMP_00973 8.5e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PHLHKCMP_00974 3.6e-196 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PHLHKCMP_00975 1.3e-190 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PHLHKCMP_00976 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PHLHKCMP_00977 2.8e-249 malT G Major Facilitator
PHLHKCMP_00979 4.1e-76 S Domain of unknown function (DUF4767)
PHLHKCMP_00980 2e-266 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PHLHKCMP_00981 8.4e-148 yitU 3.1.3.104 S hydrolase
PHLHKCMP_00982 1.4e-265 yfnA E Amino Acid
PHLHKCMP_00983 3.4e-103 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PHLHKCMP_00984 8.3e-22 L Replication initiation and membrane attachment
PHLHKCMP_00985 1.3e-95 pi346 L IstB-like ATP binding protein
PHLHKCMP_00987 1.3e-45
PHLHKCMP_00988 1.3e-15
PHLHKCMP_00990 3.3e-21 S YopX protein
PHLHKCMP_00992 1.7e-12
PHLHKCMP_00993 5e-28 S Cysteine-rich secretory protein family
PHLHKCMP_00994 1.6e-230 EGP Major facilitator Superfamily
PHLHKCMP_00995 1.1e-115 GM NmrA-like family
PHLHKCMP_00996 3.8e-81 elaA S GNAT family
PHLHKCMP_00997 1.9e-156 EG EamA-like transporter family
PHLHKCMP_00998 2.3e-257 P Major Facilitator Superfamily
PHLHKCMP_00999 3.7e-85 K Transcriptional regulator PadR-like family
PHLHKCMP_01000 2.1e-42
PHLHKCMP_01002 7.5e-65 S Domain of unknown function (DUF2479)
PHLHKCMP_01008 5.5e-08
PHLHKCMP_01018 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PHLHKCMP_01019 1.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHLHKCMP_01020 1.4e-105 L Resolvase, N terminal domain
PHLHKCMP_01021 4.5e-136 S Protease prsW family
PHLHKCMP_01022 1.4e-131 K helix_turn _helix lactose operon repressor
PHLHKCMP_01023 1.9e-245 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_01024 3.3e-62
PHLHKCMP_01026 5.2e-24 xerD L Phage integrase, N-terminal SAM-like domain
PHLHKCMP_01027 2.1e-24 xerD L Phage integrase, N-terminal SAM-like domain
PHLHKCMP_01029 1.7e-304 S Protein conserved in bacteria
PHLHKCMP_01030 1.1e-228 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
PHLHKCMP_01031 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
PHLHKCMP_01032 1.6e-32 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
PHLHKCMP_01033 1.9e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
PHLHKCMP_01034 4.9e-64 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
PHLHKCMP_01035 4.6e-224 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
PHLHKCMP_01036 2.4e-179 yfbS P Sodium:sulfate symporter transmembrane region
PHLHKCMP_01037 4.6e-98 yfbS P Sodium:sulfate symporter transmembrane region
PHLHKCMP_01038 6.2e-244 dinF V MatE
PHLHKCMP_01039 1.9e-31
PHLHKCMP_01042 1.3e-78 elaA S Acetyltransferase (GNAT) domain
PHLHKCMP_01043 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PHLHKCMP_01044 1.3e-17
PHLHKCMP_01045 1.4e-128 yhcA V MacB-like periplasmic core domain
PHLHKCMP_01046 2e-39 yhcA V MacB-like periplasmic core domain
PHLHKCMP_01047 2.9e-82 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_01048 4.5e-263 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHLHKCMP_01049 2.2e-37 EGP Major facilitator Superfamily
PHLHKCMP_01050 5.9e-80 EGP Major facilitator Superfamily
PHLHKCMP_01051 5.2e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHLHKCMP_01052 2.3e-281 ydfD K Alanine-glyoxylate amino-transferase
PHLHKCMP_01053 5.2e-102 argO S LysE type translocator
PHLHKCMP_01054 4.3e-211 arcT 2.6.1.1 E Aminotransferase
PHLHKCMP_01055 1.7e-76 argR K Regulates arginine biosynthesis genes
PHLHKCMP_01056 2.9e-12
PHLHKCMP_01057 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PHLHKCMP_01058 1e-54 yheA S Belongs to the UPF0342 family
PHLHKCMP_01059 3.4e-230 yhaO L Ser Thr phosphatase family protein
PHLHKCMP_01060 0.0 L AAA domain
PHLHKCMP_01061 1.4e-186 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
PHLHKCMP_01062 1.1e-212
PHLHKCMP_01063 5.1e-176 3.4.21.102 M Peptidase family S41
PHLHKCMP_01064 3.2e-175 K LysR substrate binding domain
PHLHKCMP_01065 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
PHLHKCMP_01066 0.0 1.3.5.4 C FAD binding domain
PHLHKCMP_01067 1e-96
PHLHKCMP_01068 1e-75 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PHLHKCMP_01069 4.2e-86 nrdI F Belongs to the NrdI family
PHLHKCMP_01070 1.7e-266 yjcE P Sodium proton antiporter
PHLHKCMP_01071 3.8e-210 yttB EGP Major facilitator Superfamily
PHLHKCMP_01072 2.1e-61 K helix_turn_helix, mercury resistance
PHLHKCMP_01073 2.5e-172 C Zinc-binding dehydrogenase
PHLHKCMP_01074 8.5e-57 S SdpI/YhfL protein family
PHLHKCMP_01075 6.6e-292 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PHLHKCMP_01076 1.5e-146 gabR K Bacterial regulatory proteins, gntR family
PHLHKCMP_01077 3.1e-86 gabR K Bacterial regulatory proteins, gntR family
PHLHKCMP_01078 1.8e-215 patA 2.6.1.1 E Aminotransferase
PHLHKCMP_01079 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PHLHKCMP_01080 1.5e-17
PHLHKCMP_01081 1.9e-125 S membrane transporter protein
PHLHKCMP_01082 6.2e-160 mleR K LysR family
PHLHKCMP_01083 1.3e-114 ylbE GM NAD(P)H-binding
PHLHKCMP_01084 8.2e-96 wecD K Acetyltransferase (GNAT) family
PHLHKCMP_01085 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PHLHKCMP_01086 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PHLHKCMP_01087 1.3e-168 ydcZ S Putative inner membrane exporter, YdcZ
PHLHKCMP_01088 2.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PHLHKCMP_01089 1.9e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PHLHKCMP_01090 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PHLHKCMP_01091 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PHLHKCMP_01092 5.9e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PHLHKCMP_01093 7.6e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PHLHKCMP_01094 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PHLHKCMP_01095 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHLHKCMP_01096 3.3e-297 pucR QT Purine catabolism regulatory protein-like family
PHLHKCMP_01097 2.7e-236 pbuX F xanthine permease
PHLHKCMP_01098 3.4e-220 pbuG S Permease family
PHLHKCMP_01099 8.1e-160 GM NmrA-like family
PHLHKCMP_01100 2.4e-101 T EAL domain
PHLHKCMP_01101 4.1e-36 T EAL domain
PHLHKCMP_01102 1.7e-93
PHLHKCMP_01103 1.5e-194 pgaC GT2 M Glycosyl transferase
PHLHKCMP_01104 9.8e-39 pgaC GT2 M Glycosyl transferase
PHLHKCMP_01105 3.2e-121 2.1.1.14 E Methionine synthase
PHLHKCMP_01106 8.7e-213 purD 6.3.4.13 F Belongs to the GARS family
PHLHKCMP_01107 4.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PHLHKCMP_01108 3.8e-102 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PHLHKCMP_01109 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PHLHKCMP_01110 1.8e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PHLHKCMP_01111 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHLHKCMP_01112 2.9e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHLHKCMP_01113 4e-40 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHLHKCMP_01114 8.4e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PHLHKCMP_01115 8.5e-207 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PHLHKCMP_01116 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PHLHKCMP_01117 3.9e-224 XK27_09615 1.3.5.4 S reductase
PHLHKCMP_01118 4.4e-109 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
PHLHKCMP_01119 1.5e-149 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
PHLHKCMP_01120 1.4e-18 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
PHLHKCMP_01121 5.3e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
PHLHKCMP_01122 1e-116 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
PHLHKCMP_01123 5.4e-147 S Alpha/beta hydrolase of unknown function (DUF915)
PHLHKCMP_01124 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
PHLHKCMP_01125 1.7e-139 cysA V ABC transporter, ATP-binding protein
PHLHKCMP_01126 0.0 V FtsX-like permease family
PHLHKCMP_01127 6.7e-41
PHLHKCMP_01128 5.1e-60 gntR1 K Transcriptional regulator, GntR family
PHLHKCMP_01129 6.9e-164 V ABC transporter, ATP-binding protein
PHLHKCMP_01130 1.4e-147
PHLHKCMP_01131 1.5e-80 uspA T universal stress protein
PHLHKCMP_01132 4e-34
PHLHKCMP_01133 1.1e-88
PHLHKCMP_01134 5.5e-50
PHLHKCMP_01136 5.6e-233 malY 4.4.1.8 E Aminotransferase, class I
PHLHKCMP_01137 3.6e-85 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
PHLHKCMP_01138 9.2e-118
PHLHKCMP_01139 2e-52
PHLHKCMP_01141 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PHLHKCMP_01142 3.6e-282 thrC 4.2.3.1 E Threonine synthase
PHLHKCMP_01143 5e-145 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
PHLHKCMP_01144 9.8e-11 mcbG S Pentapeptide repeats (8 copies)
PHLHKCMP_01145 7.1e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PHLHKCMP_01146 7.5e-103 3.6.1.13 L Belongs to the Nudix hydrolase family
PHLHKCMP_01147 7.3e-67 FG Scavenger mRNA decapping enzyme C-term binding
PHLHKCMP_01148 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
PHLHKCMP_01149 6.9e-36 XK27_01315 S Protein of unknown function (DUF2829)
PHLHKCMP_01150 3.8e-212 S Bacterial protein of unknown function (DUF871)
PHLHKCMP_01151 8.2e-229 S Sterol carrier protein domain
PHLHKCMP_01152 8.8e-76 EGP Major facilitator Superfamily
PHLHKCMP_01153 3.5e-118 EGP Major facilitator Superfamily
PHLHKCMP_01154 9.7e-86 niaR S 3H domain
PHLHKCMP_01155 1.1e-262 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHLHKCMP_01156 2.4e-116 K Transcriptional regulator
PHLHKCMP_01157 9.2e-154 V ABC transporter
PHLHKCMP_01158 2.6e-132 V AAA domain, putative AbiEii toxin, Type IV TA system
PHLHKCMP_01159 1.5e-244 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
PHLHKCMP_01160 1.5e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHLHKCMP_01161 6.2e-295 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHLHKCMP_01162 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
PHLHKCMP_01163 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PHLHKCMP_01164 3.4e-129 gntR K UTRA
PHLHKCMP_01165 9.9e-140 epsV 2.7.8.12 S glycosyl transferase family 2
PHLHKCMP_01166 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PHLHKCMP_01167 9e-81
PHLHKCMP_01168 0.0 yhcA V ABC transporter, ATP-binding protein
PHLHKCMP_01169 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PHLHKCMP_01170 1.6e-171 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PHLHKCMP_01171 1.5e-69 pip1 V domain protein
PHLHKCMP_01172 4.9e-217 EGP Major Facilitator Superfamily
PHLHKCMP_01173 2.3e-74 K Transcriptional regulator PadR-like family
PHLHKCMP_01174 4.1e-114 K UTRA
PHLHKCMP_01175 1.4e-262 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHLHKCMP_01176 8.2e-98 soj D Anion-transporting ATPase
PHLHKCMP_01177 8e-07
PHLHKCMP_01178 1.7e-08
PHLHKCMP_01179 6.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
PHLHKCMP_01180 1.5e-40 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
PHLHKCMP_01182 1.6e-193 blaA6 V Beta-lactamase
PHLHKCMP_01183 2.9e-93 V VanZ like family
PHLHKCMP_01184 5.7e-37 soj D Sporulation initiation inhibitor
PHLHKCMP_01187 2.9e-156 pepR1 3.4.11.5 I Releases the N-terminal proline from various substrates
PHLHKCMP_01188 8e-244 puuP_1 E Amino acid permease
PHLHKCMP_01189 2.7e-230 yxiO S Vacuole effluxer Atg22 like
PHLHKCMP_01190 5.1e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
PHLHKCMP_01191 1.4e-158 I alpha/beta hydrolase fold
PHLHKCMP_01192 2.4e-140
PHLHKCMP_01193 5.6e-39 S Cytochrome B5
PHLHKCMP_01194 1.3e-28 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHLHKCMP_01195 1.6e-49 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHLHKCMP_01196 2.8e-28 2.7.7.65 T Diguanylate cyclase, GGDEF domain
PHLHKCMP_01197 2.5e-98 2.7.7.65 T Diguanylate cyclase, GGDEF domain
PHLHKCMP_01198 1.7e-46 2.7.7.65 T Diguanylate cyclase, GGDEF domain
PHLHKCMP_01199 2.1e-75 yliE T EAL domain
PHLHKCMP_01200 6e-42 yliE T EAL domain
PHLHKCMP_01201 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHLHKCMP_01202 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PHLHKCMP_01203 1.3e-79
PHLHKCMP_01204 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PHLHKCMP_01205 6.4e-190 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHLHKCMP_01206 1.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHLHKCMP_01207 1.2e-13
PHLHKCMP_01208 1.5e-71
PHLHKCMP_01209 8.4e-165 K LysR substrate binding domain
PHLHKCMP_01210 1.4e-120 P Sodium:sulfate symporter transmembrane region
PHLHKCMP_01211 1.5e-104 P Sodium:sulfate symporter transmembrane region
PHLHKCMP_01212 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
PHLHKCMP_01213 9e-262 S response to antibiotic
PHLHKCMP_01214 6.5e-133 S zinc-ribbon domain
PHLHKCMP_01216 7.8e-39
PHLHKCMP_01217 4.1e-133 aroD S Alpha/beta hydrolase family
PHLHKCMP_01218 1.3e-133 S Phosphotransferase system, EIIC
PHLHKCMP_01219 2.8e-268 I acetylesterase activity
PHLHKCMP_01220 8.4e-195 sdrF M Collagen binding domain
PHLHKCMP_01221 1.1e-159 yicL EG EamA-like transporter family
PHLHKCMP_01222 1.7e-128 E lipolytic protein G-D-S-L family
PHLHKCMP_01223 4.4e-177 4.1.1.52 S Amidohydrolase
PHLHKCMP_01224 2.3e-113 K Transcriptional regulator C-terminal region
PHLHKCMP_01225 3.1e-47 3.6.4.12 K HxlR-like helix-turn-helix
PHLHKCMP_01226 1.4e-39 V ATPases associated with a variety of cellular activities
PHLHKCMP_01227 1.2e-143 soj D AAA domain
PHLHKCMP_01228 5.2e-34
PHLHKCMP_01230 9.5e-38 gtrA S GtrA-like protein
PHLHKCMP_01231 1.4e-57 pip1 V domain protein
PHLHKCMP_01235 2.2e-166 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
PHLHKCMP_01236 2.1e-47 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PHLHKCMP_01237 2.7e-152 cps4I M Glycosyltransferase like family 2
PHLHKCMP_01238 1.4e-56 hxlR K HxlR-like helix-turn-helix
PHLHKCMP_01239 2.9e-109 XK27_07075 V CAAX protease self-immunity
PHLHKCMP_01241 1.2e-67 XK27_06930 S ABC-2 family transporter protein
PHLHKCMP_01242 4.5e-129 gadC E Amino acid permease
PHLHKCMP_01243 3e-63 S Domain of unknown function (DUF2479)
PHLHKCMP_01245 4.7e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHLHKCMP_01246 2.4e-176 EG EamA-like transporter family
PHLHKCMP_01247 3.6e-166 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PHLHKCMP_01248 1.5e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PHLHKCMP_01249 1.2e-135 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
PHLHKCMP_01250 2e-138 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PHLHKCMP_01251 2.2e-246 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
PHLHKCMP_01252 3.7e-64 accB 2.3.1.12 I Biotin-requiring enzyme
PHLHKCMP_01253 1.1e-175 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PHLHKCMP_01254 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
PHLHKCMP_01255 2.5e-71 pts10A 2.7.1.191 G PTS system fructose IIA component
PHLHKCMP_01256 0.0 levR K Sigma-54 interaction domain
PHLHKCMP_01257 4.7e-64 S Domain of unknown function (DUF956)
PHLHKCMP_01258 1.2e-169 manN G system, mannose fructose sorbose family IID component
PHLHKCMP_01259 3.4e-133 manY G PTS system
PHLHKCMP_01260 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PHLHKCMP_01261 2.5e-107 G Peptidase_C39 like family
PHLHKCMP_01263 3.1e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PHLHKCMP_01264 3.4e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PHLHKCMP_01265 5.7e-82 ydcK S Belongs to the SprT family
PHLHKCMP_01266 0.0 yhgF K Tex-like protein N-terminal domain protein
PHLHKCMP_01267 3.7e-70
PHLHKCMP_01268 0.0 pacL 3.6.3.8 P P-type ATPase
PHLHKCMP_01269 3e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PHLHKCMP_01270 2.6e-288 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHLHKCMP_01271 2.5e-135 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PHLHKCMP_01272 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
PHLHKCMP_01273 8.8e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PHLHKCMP_01274 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PHLHKCMP_01275 2.4e-150 pnuC H nicotinamide mononucleotide transporter
PHLHKCMP_01276 1e-126 ybiR P Citrate transporter
PHLHKCMP_01277 5.4e-153 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
PHLHKCMP_01278 2.5e-53 S Cupin domain
PHLHKCMP_01279 3.5e-58 5.3.3.19 S Cupin 2, conserved barrel domain protein
PHLHKCMP_01281 4.2e-46 V antibiotic catabolic process
PHLHKCMP_01282 1.2e-20 qacC P COG2076 Membrane transporters of cations and cationic drugs
PHLHKCMP_01283 2.2e-101 tnp L DDE domain
PHLHKCMP_01285 2.2e-08 M Listeria-Bacteroides repeat domain (List_Bact_rpt)
PHLHKCMP_01286 1.1e-112 D CobQ CobB MinD ParA nucleotide binding domain protein
PHLHKCMP_01287 1.2e-32 S Family of unknown function (DUF5388)
PHLHKCMP_01288 4.5e-43
PHLHKCMP_01289 6.4e-162 M hydrolase, family 25
PHLHKCMP_01291 5.4e-72 S VIT family
PHLHKCMP_01292 1.6e-118 S membrane
PHLHKCMP_01293 1.5e-42 S COG NOG38524 non supervised orthologous group
PHLHKCMP_01294 1.4e-155
PHLHKCMP_01295 1e-165 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
PHLHKCMP_01296 8.5e-99 nox C NADH oxidase
PHLHKCMP_01297 6.6e-21 nox C NADH oxidase
PHLHKCMP_01298 2.3e-122 yliE T Putative diguanylate phosphodiesterase
PHLHKCMP_01299 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PHLHKCMP_01300 2.7e-180 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PHLHKCMP_01301 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PHLHKCMP_01302 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PHLHKCMP_01303 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PHLHKCMP_01304 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
PHLHKCMP_01305 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
PHLHKCMP_01306 6.6e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHLHKCMP_01307 2.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHLHKCMP_01308 1.5e-155 pstA P Phosphate transport system permease protein PstA
PHLHKCMP_01309 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
PHLHKCMP_01310 1.1e-150 pstS P Phosphate
PHLHKCMP_01311 3e-249 phoR 2.7.13.3 T Histidine kinase
PHLHKCMP_01312 1.5e-132 K response regulator
PHLHKCMP_01313 1e-215 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
PHLHKCMP_01314 1e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PHLHKCMP_01315 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHLHKCMP_01316 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PHLHKCMP_01317 1.2e-123 comFC S Competence protein
PHLHKCMP_01318 9.9e-112 comFA L Helicase C-terminal domain protein
PHLHKCMP_01319 1.4e-77 comFA L Helicase C-terminal domain protein
PHLHKCMP_01320 1.1e-113 yvyE 3.4.13.9 S YigZ family
PHLHKCMP_01321 1.6e-144 pstS P Phosphate
PHLHKCMP_01322 8.6e-180 tagO 2.7.8.33, 2.7.8.35 M transferase
PHLHKCMP_01323 0.0 ydaO E amino acid
PHLHKCMP_01324 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PHLHKCMP_01325 5e-23 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PHLHKCMP_01326 2.3e-108 ydiL S CAAX protease self-immunity
PHLHKCMP_01327 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PHLHKCMP_01328 3.2e-302 uup S ABC transporter, ATP-binding protein
PHLHKCMP_01329 5.9e-120 2.7.7.73, 2.7.7.80 H ThiF family
PHLHKCMP_01330 1.2e-34 EGP Major facilitator Superfamily
PHLHKCMP_01331 2.2e-39 S Protein of unknown function (DUF1722)
PHLHKCMP_01332 5.5e-49 S Pyrimidine dimer DNA glycosylase
PHLHKCMP_01333 4.7e-61 lmrB EGP Major facilitator Superfamily
PHLHKCMP_01334 4.6e-26 M Lysin motif
PHLHKCMP_01335 3.9e-81
PHLHKCMP_01336 1.1e-10 S DNA/RNA non-specific endonuclease
PHLHKCMP_01340 2.6e-44 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_01341 2.7e-50 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_01342 1.7e-113 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
PHLHKCMP_01343 8.1e-182 S Oxidoreductase family, NAD-binding Rossmann fold
PHLHKCMP_01344 1.7e-193 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PHLHKCMP_01345 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PHLHKCMP_01346 2e-100 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PHLHKCMP_01347 1.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PHLHKCMP_01348 3.3e-189 phnD P Phosphonate ABC transporter
PHLHKCMP_01349 9.1e-136 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PHLHKCMP_01350 7.3e-136 phnE 3.6.1.63 U Phosphonate ABC transporter permease
PHLHKCMP_01351 8.8e-13 phnE1 3.6.1.63 U ABC transporter permease
PHLHKCMP_01352 2.5e-107 phnE1 3.6.1.63 U ABC transporter permease
PHLHKCMP_01353 4.4e-141 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
PHLHKCMP_01354 3.9e-209 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
PHLHKCMP_01355 9.8e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PHLHKCMP_01356 6.8e-147 fat 3.1.2.21 I Acyl-ACP thioesterase
PHLHKCMP_01357 4.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PHLHKCMP_01358 1e-57 yabA L Involved in initiation control of chromosome replication
PHLHKCMP_01359 9.7e-186 holB 2.7.7.7 L DNA polymerase III
PHLHKCMP_01360 2.4e-53 yaaQ S Cyclic-di-AMP receptor
PHLHKCMP_01361 7.4e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PHLHKCMP_01362 1.5e-42 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PHLHKCMP_01363 1.6e-13 L Helix-turn-helix domain
PHLHKCMP_01364 2.2e-38 yaaL S Protein of unknown function (DUF2508)
PHLHKCMP_01365 2.4e-91 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PHLHKCMP_01366 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PHLHKCMP_01367 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHLHKCMP_01368 1.7e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PHLHKCMP_01369 1.3e-108 rsmC 2.1.1.172 J Methyltransferase
PHLHKCMP_01370 6.5e-37 nrdH O Glutaredoxin
PHLHKCMP_01371 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHLHKCMP_01372 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHLHKCMP_01373 6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
PHLHKCMP_01374 5.5e-34 K Helix-turn-helix domain
PHLHKCMP_01375 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHLHKCMP_01376 9.2e-19 L nuclease
PHLHKCMP_01377 8.5e-23 L nuclease
PHLHKCMP_01378 1.5e-11 F DNA/RNA non-specific endonuclease
PHLHKCMP_01379 2.1e-86 F DNA/RNA non-specific endonuclease
PHLHKCMP_01380 2e-71 V Abi-like protein
PHLHKCMP_01381 8.7e-28 hol S Bacteriophage holin
PHLHKCMP_01382 4.7e-48
PHLHKCMP_01383 3.2e-166 M Glycosyl hydrolases family 25
PHLHKCMP_01384 2.5e-30
PHLHKCMP_01386 1.7e-25 K Cro/C1-type HTH DNA-binding domain
PHLHKCMP_01387 4.2e-52
PHLHKCMP_01388 8.7e-19
PHLHKCMP_01389 3.9e-35 S Transcriptional regulator, RinA family
PHLHKCMP_01390 1.7e-111 dkgB S Aldo/keto reductase family
PHLHKCMP_01392 6.4e-77 K Peptidase S24-like
PHLHKCMP_01393 1.5e-169 ica2 GT2 M Glycosyl transferase family group 2
PHLHKCMP_01394 1.3e-87 K Winged helix DNA-binding domain
PHLHKCMP_01395 1.4e-114 treR K UTRA
PHLHKCMP_01397 9.9e-69 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_01400 4.3e-178 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PHLHKCMP_01401 9.7e-26
PHLHKCMP_01402 3.7e-29
PHLHKCMP_01403 5.2e-30 S PFAM Uncharacterised protein family UPF0150
PHLHKCMP_01405 5.6e-20 xerC L Phage integrase, N-terminal SAM-like domain
PHLHKCMP_01410 4.9e-54 M CHAP domain
PHLHKCMP_01416 1.4e-42 clpB O C-terminal, D2-small domain, of ClpB protein
PHLHKCMP_01420 5.8e-07
PHLHKCMP_01421 9.2e-09 himA K This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
PHLHKCMP_01424 3.5e-27 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
PHLHKCMP_01425 8.6e-91 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
PHLHKCMP_01426 3.2e-23 3.4.22.70 M Sortase family
PHLHKCMP_01429 1.2e-25
PHLHKCMP_01430 1.4e-131 D CobQ CobB MinD ParA nucleotide binding domain protein
PHLHKCMP_01432 1e-63 K Winged helix DNA-binding domain
PHLHKCMP_01433 5.7e-75 livJ E Receptor family ligand binding region
PHLHKCMP_01435 1.5e-111 S WxL domain surface cell wall-binding
PHLHKCMP_01436 3.9e-139 K Helix-turn-helix domain
PHLHKCMP_01438 1.3e-31 L hmm pf00665
PHLHKCMP_01439 1.7e-57 L hmm pf00665
PHLHKCMP_01440 3.2e-78
PHLHKCMP_01441 1.3e-243 pgaC GT2 M Glycosyl transferase
PHLHKCMP_01442 1.8e-133 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
PHLHKCMP_01443 1e-62 hxlR K Transcriptional regulator, HxlR family
PHLHKCMP_01444 2.8e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PHLHKCMP_01445 2.5e-239 yrvN L AAA C-terminal domain
PHLHKCMP_01446 2.4e-55
PHLHKCMP_01447 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PHLHKCMP_01448 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PHLHKCMP_01449 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PHLHKCMP_01450 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PHLHKCMP_01451 6.8e-170 dnaI L Primosomal protein DnaI
PHLHKCMP_01452 6.7e-246 dnaB L replication initiation and membrane attachment
PHLHKCMP_01453 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PHLHKCMP_01454 8.6e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PHLHKCMP_01455 2.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PHLHKCMP_01456 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PHLHKCMP_01457 4.5e-121 ybhL S Belongs to the BI1 family
PHLHKCMP_01458 2.3e-111 hipB K Helix-turn-helix
PHLHKCMP_01459 5.5e-45 yitW S Iron-sulfur cluster assembly protein
PHLHKCMP_01460 5.5e-272 sufB O assembly protein SufB
PHLHKCMP_01461 2.1e-82 nifU C SUF system FeS assembly protein, NifU family
PHLHKCMP_01462 4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PHLHKCMP_01463 1.7e-243 sufD O FeS assembly protein SufD
PHLHKCMP_01464 2.7e-143 sufC O FeS assembly ATPase SufC
PHLHKCMP_01465 1.3e-34 feoA P FeoA domain
PHLHKCMP_01466 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PHLHKCMP_01467 7.9e-21 S Virus attachment protein p12 family
PHLHKCMP_01468 2.4e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PHLHKCMP_01469 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
PHLHKCMP_01470 1.8e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHLHKCMP_01471 2.4e-59 L Helix-turn-helix domain
PHLHKCMP_01472 6.3e-91
PHLHKCMP_01473 1.7e-42
PHLHKCMP_01475 5.5e-09 UW LPXTG-motif cell wall anchor domain protein
PHLHKCMP_01476 1.3e-34 S Bacterial membrane protein, YfhO
PHLHKCMP_01478 2.6e-37 L 4.5 Transposon and IS
PHLHKCMP_01479 1.6e-44 K sequence-specific DNA binding
PHLHKCMP_01480 2.2e-87 S AAA domain
PHLHKCMP_01483 1e-64 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
PHLHKCMP_01484 4e-66 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
PHLHKCMP_01485 1.3e-293 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
PHLHKCMP_01486 7.2e-92 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
PHLHKCMP_01487 2.6e-44 S MazG-like family
PHLHKCMP_01488 0.0 N Uncharacterized conserved protein (DUF2075)
PHLHKCMP_01489 0.0 pepN 3.4.11.2 E aminopeptidase
PHLHKCMP_01490 2.4e-101 G Glycogen debranching enzyme
PHLHKCMP_01491 1.2e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PHLHKCMP_01492 2.6e-159 yjdB S Domain of unknown function (DUF4767)
PHLHKCMP_01493 9.1e-107 Q Fumarylacetoacetate (FAA) hydrolase family
PHLHKCMP_01494 5.9e-10 Q Fumarylacetoacetate (FAA) hydrolase family
PHLHKCMP_01495 2e-71 asp2 S Asp23 family, cell envelope-related function
PHLHKCMP_01496 4.3e-71 asp S Asp23 family, cell envelope-related function
PHLHKCMP_01497 7.2e-23
PHLHKCMP_01498 1.1e-82
PHLHKCMP_01499 7.1e-37 S Transglycosylase associated protein
PHLHKCMP_01500 4.5e-73 XK27_09800 I Acyltransferase family
PHLHKCMP_01501 4.5e-73 XK27_09800 I Acyltransferase family
PHLHKCMP_01502 7.1e-37 S Transglycosylase associated protein
PHLHKCMP_01503 1.1e-82
PHLHKCMP_01504 7.2e-23
PHLHKCMP_01505 4.3e-71 asp S Asp23 family, cell envelope-related function
PHLHKCMP_01506 2e-71 asp2 S Asp23 family, cell envelope-related function
PHLHKCMP_01507 5.9e-10 Q Fumarylacetoacetate (FAA) hydrolase family
PHLHKCMP_01508 9.1e-107 Q Fumarylacetoacetate (FAA) hydrolase family
PHLHKCMP_01509 2.6e-159 yjdB S Domain of unknown function (DUF4767)
PHLHKCMP_01510 1.2e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PHLHKCMP_01511 2.4e-101 G Glycogen debranching enzyme
PHLHKCMP_01512 0.0 pepN 3.4.11.2 E aminopeptidase
PHLHKCMP_01513 0.0 N Uncharacterized conserved protein (DUF2075)
PHLHKCMP_01514 2.6e-44 S MazG-like family
PHLHKCMP_01515 7.2e-92 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
PHLHKCMP_01516 1.3e-293 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
PHLHKCMP_01517 4e-66 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
PHLHKCMP_01518 1e-64 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
PHLHKCMP_01521 2.2e-87 S AAA domain
PHLHKCMP_01522 1.6e-44 K sequence-specific DNA binding
PHLHKCMP_01523 2.9e-43 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_01525 8e-21
PHLHKCMP_01526 2.7e-283 mntH P H( )-stimulated, divalent metal cation uptake system
PHLHKCMP_01527 6.8e-72 T Belongs to the universal stress protein A family
PHLHKCMP_01528 1.1e-46
PHLHKCMP_01529 9.2e-116 S SNARE associated Golgi protein
PHLHKCMP_01530 2e-49 K Transcriptional regulator, ArsR family
PHLHKCMP_01531 1.2e-95 cadD P Cadmium resistance transporter
PHLHKCMP_01532 4.4e-35 yyaN K MerR HTH family regulatory protein
PHLHKCMP_01533 3.2e-119 azlC E branched-chain amino acid
PHLHKCMP_01534 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
PHLHKCMP_01535 0.0 asnB 6.3.5.4 E Asparagine synthase
PHLHKCMP_01536 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
PHLHKCMP_01537 2e-280 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PHLHKCMP_01538 5.6e-122 xylP2 G symporter
PHLHKCMP_01539 1.1e-107 xylP2 G symporter
PHLHKCMP_01540 2.1e-13 nlhH_1 I alpha/beta hydrolase fold
PHLHKCMP_01541 6.9e-167 nlhH_1 I alpha/beta hydrolase fold
PHLHKCMP_01542 3.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PHLHKCMP_01543 1.1e-101 3.2.2.20 K FR47-like protein
PHLHKCMP_01544 1.3e-126 yibF S overlaps another CDS with the same product name
PHLHKCMP_01545 4.7e-197 yibE S overlaps another CDS with the same product name
PHLHKCMP_01546 1.4e-176
PHLHKCMP_01547 1.6e-120 S NADPH-dependent FMN reductase
PHLHKCMP_01548 5.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
PHLHKCMP_01549 8.4e-162 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PHLHKCMP_01550 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PHLHKCMP_01551 4.1e-32 L leucine-zipper of insertion element IS481
PHLHKCMP_01552 8.5e-41
PHLHKCMP_01553 7.3e-09 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PHLHKCMP_01554 2.3e-185 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PHLHKCMP_01555 5.7e-277 pipD E Dipeptidase
PHLHKCMP_01556 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
PHLHKCMP_01557 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PHLHKCMP_01558 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PHLHKCMP_01559 5.7e-80 rmaD K Transcriptional regulator
PHLHKCMP_01560 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
PHLHKCMP_01561 5.6e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHLHKCMP_01562 5.1e-53 yitW S Pfam:DUF59
PHLHKCMP_01563 3.8e-173 S Aldo keto reductase
PHLHKCMP_01564 1.6e-96 FG HIT domain
PHLHKCMP_01565 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
PHLHKCMP_01566 1.5e-76
PHLHKCMP_01567 1.3e-47 E GDSL-like Lipase/Acylhydrolase family
PHLHKCMP_01568 1.4e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
PHLHKCMP_01569 0.0 cadA P P-type ATPase
PHLHKCMP_01571 1.3e-122 yyaQ S YjbR
PHLHKCMP_01572 2.7e-219 S Uncharacterized protein conserved in bacteria (DUF2325)
PHLHKCMP_01573 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PHLHKCMP_01574 3.4e-197 frlB M SIS domain
PHLHKCMP_01575 1.2e-25 3.2.2.10 S Belongs to the LOG family
PHLHKCMP_01576 5.8e-253 nhaC C Na H antiporter NhaC
PHLHKCMP_01577 2.4e-251 cycA E Amino acid permease
PHLHKCMP_01578 5.3e-167 S Alpha/beta hydrolase of unknown function (DUF915)
PHLHKCMP_01579 1.6e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
PHLHKCMP_01580 2.2e-162 azoB GM NmrA-like family
PHLHKCMP_01581 5.8e-68 K Winged helix DNA-binding domain
PHLHKCMP_01582 7e-71 spx4 1.20.4.1 P ArsC family
PHLHKCMP_01583 8.2e-66 yeaO S Protein of unknown function, DUF488
PHLHKCMP_01584 4e-53
PHLHKCMP_01585 3.8e-212 mutY L A G-specific adenine glycosylase
PHLHKCMP_01586 1.9e-62
PHLHKCMP_01587 4.3e-86
PHLHKCMP_01588 3.4e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
PHLHKCMP_01589 1e-54
PHLHKCMP_01590 2.1e-14
PHLHKCMP_01591 2.7e-186 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PHLHKCMP_01592 3e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
PHLHKCMP_01593 8.8e-128 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
PHLHKCMP_01594 7.8e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PHLHKCMP_01595 3.6e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PHLHKCMP_01596 3.8e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PHLHKCMP_01597 4.5e-169 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PHLHKCMP_01598 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PHLHKCMP_01599 4.2e-133 P ATPases associated with a variety of cellular activities
PHLHKCMP_01600 3.4e-130 ssuC2 U Binding-protein-dependent transport system inner membrane component
PHLHKCMP_01601 2.9e-193 P ABC transporter, substratebinding protein
PHLHKCMP_01602 8.2e-310 kup P Transport of potassium into the cell
PHLHKCMP_01603 4.9e-21 kup P Transport of potassium into the cell
PHLHKCMP_01604 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
PHLHKCMP_01605 3.2e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PHLHKCMP_01606 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PHLHKCMP_01607 2.8e-256 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PHLHKCMP_01608 1.8e-259 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PHLHKCMP_01609 2e-146
PHLHKCMP_01610 1e-138 htpX O Belongs to the peptidase M48B family
PHLHKCMP_01611 1.7e-91 lemA S LemA family
PHLHKCMP_01612 2.1e-126 srtA 3.4.22.70 M sortase family
PHLHKCMP_01613 9.7e-211 J translation release factor activity
PHLHKCMP_01614 7.8e-41 rpmE2 J Ribosomal protein L31
PHLHKCMP_01615 3e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PHLHKCMP_01616 1e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHLHKCMP_01617 5.1e-27
PHLHKCMP_01618 2.3e-119 lssY 3.6.1.27 I phosphatase
PHLHKCMP_01619 2e-154 I alpha/beta hydrolase fold
PHLHKCMP_01620 5.3e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
PHLHKCMP_01621 1.1e-89 K Transcriptional regulator
PHLHKCMP_01622 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PHLHKCMP_01623 2.5e-264 lysP E amino acid
PHLHKCMP_01624 9.4e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PHLHKCMP_01625 5.6e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PHLHKCMP_01626 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PHLHKCMP_01634 6.9e-78 ctsR K Belongs to the CtsR family
PHLHKCMP_01635 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PHLHKCMP_01636 1.5e-109 K Bacterial regulatory proteins, tetR family
PHLHKCMP_01637 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHLHKCMP_01638 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHLHKCMP_01639 2.7e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PHLHKCMP_01640 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PHLHKCMP_01641 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PHLHKCMP_01642 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PHLHKCMP_01643 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PHLHKCMP_01644 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PHLHKCMP_01645 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
PHLHKCMP_01646 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PHLHKCMP_01647 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PHLHKCMP_01648 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PHLHKCMP_01649 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PHLHKCMP_01650 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PHLHKCMP_01651 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PHLHKCMP_01652 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
PHLHKCMP_01653 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PHLHKCMP_01654 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PHLHKCMP_01655 5.3e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PHLHKCMP_01656 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PHLHKCMP_01657 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PHLHKCMP_01658 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PHLHKCMP_01659 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PHLHKCMP_01660 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PHLHKCMP_01661 2.2e-24 rpmD J Ribosomal protein L30
PHLHKCMP_01662 9.2e-69 rplO J Binds to the 23S rRNA
PHLHKCMP_01663 2.6e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PHLHKCMP_01664 6.2e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PHLHKCMP_01665 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PHLHKCMP_01666 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PHLHKCMP_01667 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PHLHKCMP_01668 2.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHLHKCMP_01669 6.2e-61 rplQ J Ribosomal protein L17
PHLHKCMP_01670 3.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PHLHKCMP_01671 9.2e-93 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
PHLHKCMP_01672 4.2e-86 ynhH S NusG domain II
PHLHKCMP_01673 0.0 ndh 1.6.99.3 C NADH dehydrogenase
PHLHKCMP_01674 3.5e-142 cad S FMN_bind
PHLHKCMP_01675 1.7e-207 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHLHKCMP_01676 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHLHKCMP_01677 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHLHKCMP_01678 1.9e-144 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHLHKCMP_01679 2.5e-149 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PHLHKCMP_01680 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PHLHKCMP_01681 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PHLHKCMP_01682 3.4e-163 degV S Uncharacterised protein, DegV family COG1307
PHLHKCMP_01683 3.3e-41 ywhK S Membrane
PHLHKCMP_01684 4.4e-80 ywhK S Membrane
PHLHKCMP_01685 3.5e-202 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PHLHKCMP_01686 1.8e-18 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PHLHKCMP_01687 8.7e-193 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PHLHKCMP_01688 1.7e-70 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PHLHKCMP_01689 5.2e-143 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PHLHKCMP_01690 1e-179 aroF 2.5.1.54 E DAHP synthetase I family
PHLHKCMP_01691 4.6e-16 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PHLHKCMP_01692 6e-77 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PHLHKCMP_01693 1.5e-74 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PHLHKCMP_01695 3.2e-215 P Sodium:sulfate symporter transmembrane region
PHLHKCMP_01696 3.2e-50 yitW S Iron-sulfur cluster assembly protein
PHLHKCMP_01697 6.6e-113 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
PHLHKCMP_01698 8.3e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
PHLHKCMP_01699 2.5e-132 K Helix-turn-helix domain
PHLHKCMP_01700 3e-51 K Helix-turn-helix domain
PHLHKCMP_01701 1.2e-152 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PHLHKCMP_01702 6.4e-131 mntB 3.6.3.35 P ABC transporter
PHLHKCMP_01703 2.4e-140 mtsB U ABC 3 transport family
PHLHKCMP_01704 3.9e-173 sitA P Belongs to the bacterial solute-binding protein 9 family
PHLHKCMP_01705 3.1e-50
PHLHKCMP_01706 5.7e-41 yazA L GIY-YIG catalytic domain protein
PHLHKCMP_01707 6.4e-134 yabB 2.1.1.223 L Methyltransferase small domain
PHLHKCMP_01708 3.5e-117 plsC 2.3.1.51 I Acyltransferase
PHLHKCMP_01709 2.8e-32 yneF S Uncharacterised protein family (UPF0154)
PHLHKCMP_01710 8.4e-36 ynzC S UPF0291 protein
PHLHKCMP_01711 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PHLHKCMP_01712 1.6e-93 alkD L DNA alkylation repair enzyme
PHLHKCMP_01713 7e-86
PHLHKCMP_01714 1.7e-210 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PHLHKCMP_01715 6.4e-60
PHLHKCMP_01716 6.4e-41
PHLHKCMP_01717 1.1e-175 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
PHLHKCMP_01718 7.3e-168 S Psort location CytoplasmicMembrane, score
PHLHKCMP_01720 1.1e-27
PHLHKCMP_01725 3.4e-29
PHLHKCMP_01726 9.9e-143 Q Methyltransferase
PHLHKCMP_01727 1.9e-56 ybjQ S Belongs to the UPF0145 family
PHLHKCMP_01728 2.5e-209 EGP Major facilitator Superfamily
PHLHKCMP_01729 5e-102 K Helix-turn-helix domain
PHLHKCMP_01730 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PHLHKCMP_01731 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PHLHKCMP_01732 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
PHLHKCMP_01733 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PHLHKCMP_01734 4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PHLHKCMP_01735 3.2e-46
PHLHKCMP_01736 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PHLHKCMP_01737 1.5e-135 fruR K DeoR C terminal sensor domain
PHLHKCMP_01738 1.5e-169 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PHLHKCMP_01739 7.4e-291 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
PHLHKCMP_01740 9.8e-127 cpdA S Calcineurin-like phosphoesterase
PHLHKCMP_01741 6.6e-99 cpdA S Calcineurin-like phosphoesterase
PHLHKCMP_01742 5.8e-107 cps4J S Polysaccharide biosynthesis protein
PHLHKCMP_01743 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PHLHKCMP_01744 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PHLHKCMP_01745 1.6e-269 glnPH2 P ABC transporter permease
PHLHKCMP_01746 4.3e-22
PHLHKCMP_01747 9.9e-73 S Iron-sulphur cluster biosynthesis
PHLHKCMP_01748 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PHLHKCMP_01749 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PHLHKCMP_01750 9.7e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PHLHKCMP_01751 5.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PHLHKCMP_01752 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PHLHKCMP_01753 2.9e-157 S Tetratricopeptide repeat
PHLHKCMP_01754 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHLHKCMP_01755 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PHLHKCMP_01756 1.2e-187 mdtG EGP Major Facilitator Superfamily
PHLHKCMP_01757 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PHLHKCMP_01758 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
PHLHKCMP_01759 7.7e-186 holA 2.7.7.7 L DNA polymerase III delta subunit
PHLHKCMP_01760 2e-70 comEC S Competence protein ComEC
PHLHKCMP_01761 3.2e-242 comEC S Competence protein ComEC
PHLHKCMP_01762 1.2e-80 comEB 3.5.4.12 F ComE operon protein 2
PHLHKCMP_01763 3.7e-94 comEA L Competence protein ComEA
PHLHKCMP_01764 6.2e-196 ylbL T Belongs to the peptidase S16 family
PHLHKCMP_01765 8.8e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PHLHKCMP_01766 2.4e-101 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PHLHKCMP_01767 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PHLHKCMP_01768 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PHLHKCMP_01769 1.4e-204 ftsW D Belongs to the SEDS family
PHLHKCMP_01770 2.9e-182
PHLHKCMP_01771 2.1e-55
PHLHKCMP_01772 7.7e-166 mleR K LysR substrate binding domain
PHLHKCMP_01773 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PHLHKCMP_01774 4.5e-214 nhaC C Na H antiporter NhaC
PHLHKCMP_01775 2.1e-163 3.5.1.10 C nadph quinone reductase
PHLHKCMP_01776 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PHLHKCMP_01777 2.9e-171 scrR K Transcriptional regulator, LacI family
PHLHKCMP_01778 7.1e-302 scrB 3.2.1.26 GH32 G invertase
PHLHKCMP_01779 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
PHLHKCMP_01780 3.9e-78 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PHLHKCMP_01781 2.6e-73 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PHLHKCMP_01782 1.2e-266 3.2.1.96 G Glycosyl hydrolase family 85
PHLHKCMP_01783 5e-243 3.2.1.96 G Glycosyl hydrolase family 85
PHLHKCMP_01784 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PHLHKCMP_01785 3.4e-208 msmK P Belongs to the ABC transporter superfamily
PHLHKCMP_01786 1e-259 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
PHLHKCMP_01787 2.7e-149 malA S maltodextrose utilization protein MalA
PHLHKCMP_01788 9.7e-150 malD P ABC transporter permease
PHLHKCMP_01789 5.6e-71 malC P Binding-protein-dependent transport system inner membrane component
PHLHKCMP_01790 1.1e-42 malC P Binding-protein-dependent transport system inner membrane component
PHLHKCMP_01791 7.3e-84 malC P Binding-protein-dependent transport system inner membrane component
PHLHKCMP_01792 3.7e-193 mdxE G Bacterial extracellular solute-binding protein
PHLHKCMP_01793 3.2e-27 mdxE G Bacterial extracellular solute-binding protein
PHLHKCMP_01794 8.3e-78 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
PHLHKCMP_01795 2.5e-202 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
PHLHKCMP_01796 1.4e-245 steT E amino acid
PHLHKCMP_01797 3.5e-114 G YdjC-like protein
PHLHKCMP_01798 1.4e-50 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
PHLHKCMP_01799 1.3e-151 K CAT RNA binding domain
PHLHKCMP_01800 1e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHLHKCMP_01801 4e-108 glnP P ABC transporter permease
PHLHKCMP_01802 1.6e-109 gluC P ABC transporter permease
PHLHKCMP_01803 7.8e-149 glnH ET ABC transporter substrate-binding protein
PHLHKCMP_01804 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PHLHKCMP_01806 3.6e-41
PHLHKCMP_01807 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHLHKCMP_01808 3.3e-209 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PHLHKCMP_01809 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
PHLHKCMP_01811 6.4e-148
PHLHKCMP_01812 7.1e-12 3.2.1.14 GH18
PHLHKCMP_01813 6.3e-81 zur P Belongs to the Fur family
PHLHKCMP_01814 1e-102 gmk2 2.7.4.8 F Guanylate kinase
PHLHKCMP_01815 1.8e-19
PHLHKCMP_01816 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
PHLHKCMP_01817 2.9e-148 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PHLHKCMP_01818 9.7e-88
PHLHKCMP_01819 1.1e-251 yfnA E Amino Acid
PHLHKCMP_01820 2.9e-45
PHLHKCMP_01821 8e-67 O OsmC-like protein
PHLHKCMP_01822 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PHLHKCMP_01823 0.0 oatA I Acyltransferase
PHLHKCMP_01824 2e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PHLHKCMP_01825 3.6e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
PHLHKCMP_01826 7.1e-308 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PHLHKCMP_01830 4.5e-10 D nuclear chromosome segregation
PHLHKCMP_01831 5.6e-09 S HicB_like antitoxin of bacterial toxin-antitoxin system
PHLHKCMP_01834 2.8e-51
PHLHKCMP_01838 1.7e-26
PHLHKCMP_01840 1.6e-32 K Helix-turn-helix domain
PHLHKCMP_01841 2.4e-46 S Phage derived protein Gp49-like (DUF891)
PHLHKCMP_01843 1.3e-19 ftsK D FtsK SpoIIIE family protein
PHLHKCMP_01844 1.6e-83 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
PHLHKCMP_01846 8.9e-10
PHLHKCMP_01852 5.1e-17
PHLHKCMP_01854 1.7e-08
PHLHKCMP_01857 8.6e-127 sip L Belongs to the 'phage' integrase family
PHLHKCMP_01858 1e-53 sip L Belongs to the 'phage' integrase family
PHLHKCMP_01859 5.8e-35
PHLHKCMP_01860 1e-87 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PHLHKCMP_01861 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PHLHKCMP_01863 3.6e-275 E ABC transporter, substratebinding protein
PHLHKCMP_01864 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PHLHKCMP_01865 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PHLHKCMP_01866 8.8e-226 yttB EGP Major facilitator Superfamily
PHLHKCMP_01867 1.3e-241 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PHLHKCMP_01868 1.4e-67 rplI J Binds to the 23S rRNA
PHLHKCMP_01869 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PHLHKCMP_01870 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PHLHKCMP_01871 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PHLHKCMP_01872 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
PHLHKCMP_01873 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHLHKCMP_01874 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHLHKCMP_01875 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PHLHKCMP_01876 5e-37 yaaA S S4 domain protein YaaA
PHLHKCMP_01877 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PHLHKCMP_01878 2.7e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PHLHKCMP_01879 2.9e-128 treR K UTRA
PHLHKCMP_01880 2.9e-196 S Bacterial membrane protein, YfhO
PHLHKCMP_01881 4.3e-141 pnuC H nicotinamide mononucleotide transporter
PHLHKCMP_01882 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
PHLHKCMP_01883 5.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PHLHKCMP_01884 3.7e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PHLHKCMP_01885 3.6e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
PHLHKCMP_01886 5.2e-167 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
PHLHKCMP_01887 2.9e-21 S Bacterial protein of unknown function (DUF871)
PHLHKCMP_01888 1.5e-37
PHLHKCMP_01889 2.3e-225 pts3C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_01890 1.3e-123 K helix_turn_helix gluconate operon transcriptional repressor
PHLHKCMP_01891 5.4e-98 yieF S NADPH-dependent FMN reductase
PHLHKCMP_01892 7.6e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
PHLHKCMP_01893 3.9e-81 ndk 2.7.4.6 F Belongs to the NDK family
PHLHKCMP_01894 2e-62
PHLHKCMP_01895 4.7e-94
PHLHKCMP_01896 2.4e-45
PHLHKCMP_01897 2e-55 trxA1 O Belongs to the thioredoxin family
PHLHKCMP_01898 1.7e-67
PHLHKCMP_01899 1.1e-220 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
PHLHKCMP_01900 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_01901 0.0 mtlR K Mga helix-turn-helix domain
PHLHKCMP_01902 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
PHLHKCMP_01903 2.5e-35 pipD E Dipeptidase
PHLHKCMP_01904 2.6e-205 pipD E Dipeptidase
PHLHKCMP_01905 3.6e-99 K Helix-turn-helix domain
PHLHKCMP_01906 2.1e-149 qorB 1.6.5.2 GM NmrA-like family
PHLHKCMP_01907 2.9e-148 cof S haloacid dehalogenase-like hydrolase
PHLHKCMP_01908 1.4e-92 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PHLHKCMP_01909 1.1e-305 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
PHLHKCMP_01910 5.9e-105 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
PHLHKCMP_01911 1.6e-10 mngA 2.7.1.195, 2.7.1.202 G Psort location CytoplasmicMembrane, score
PHLHKCMP_01912 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
PHLHKCMP_01913 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PHLHKCMP_01914 2.9e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHLHKCMP_01915 2e-77 merR K MerR family regulatory protein
PHLHKCMP_01916 1.4e-156 1.6.5.2 GM NmrA-like family
PHLHKCMP_01917 2.7e-211 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_01918 4.4e-46 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_01919 1.1e-63 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_01920 1.1e-126 magIII L Base excision DNA repair protein, HhH-GPD family
PHLHKCMP_01921 1.4e-08
PHLHKCMP_01922 2e-100 S NADPH-dependent FMN reductase
PHLHKCMP_01923 1.3e-235 S module of peptide synthetase
PHLHKCMP_01924 5.9e-59
PHLHKCMP_01925 9.8e-88 perR P Belongs to the Fur family
PHLHKCMP_01926 1.6e-58 S Enterocin A Immunity
PHLHKCMP_01927 6e-35 S Phospholipase_D-nuclease N-terminal
PHLHKCMP_01928 2.7e-165 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
PHLHKCMP_01929 3.8e-104 J Acetyltransferase (GNAT) domain
PHLHKCMP_01930 5.1e-64 lrgA S LrgA family
PHLHKCMP_01931 7.3e-127 lrgB M LrgB-like family
PHLHKCMP_01932 2.5e-145 DegV S EDD domain protein, DegV family
PHLHKCMP_01933 4.1e-25
PHLHKCMP_01934 3.5e-118 yugP S Putative neutral zinc metallopeptidase
PHLHKCMP_01935 1e-40
PHLHKCMP_01936 2e-250 ydiC1 EGP Major facilitator Superfamily
PHLHKCMP_01937 9.5e-65 K helix_turn_helix, mercury resistance
PHLHKCMP_01938 3.4e-250 T PhoQ Sensor
PHLHKCMP_01939 4.1e-127 K Transcriptional regulatory protein, C terminal
PHLHKCMP_01940 1.8e-49
PHLHKCMP_01941 1e-128 yidA K Helix-turn-helix domain, rpiR family
PHLHKCMP_01942 2.3e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_01943 9.3e-55
PHLHKCMP_01944 6.2e-41
PHLHKCMP_01945 2e-183 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PHLHKCMP_01946 2e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
PHLHKCMP_01947 3.8e-47
PHLHKCMP_01948 6.1e-123 2.7.6.5 S RelA SpoT domain protein
PHLHKCMP_01949 3.4e-103 K transcriptional regulator
PHLHKCMP_01950 0.0 ydgH S MMPL family
PHLHKCMP_01951 5e-107 tag 3.2.2.20 L glycosylase
PHLHKCMP_01952 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
PHLHKCMP_01953 1.7e-194 yclI V MacB-like periplasmic core domain
PHLHKCMP_01954 1e-119 yclH V ABC transporter
PHLHKCMP_01955 2.7e-109 V CAAX protease self-immunity
PHLHKCMP_01956 5.7e-116 S CAAX protease self-immunity
PHLHKCMP_01957 2.2e-49 M Lysin motif
PHLHKCMP_01958 1.9e-121 rfbP M Bacterial sugar transferase
PHLHKCMP_01959 3.8e-53
PHLHKCMP_01960 3.6e-32 S Protein of unknown function (DUF2922)
PHLHKCMP_01961 7.8e-29
PHLHKCMP_01962 2.4e-24
PHLHKCMP_01963 3e-101 K DNA-templated transcription, initiation
PHLHKCMP_01964 1.5e-60
PHLHKCMP_01965 4.4e-26
PHLHKCMP_01966 6.3e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
PHLHKCMP_01967 4.1e-106 ygaC J Belongs to the UPF0374 family
PHLHKCMP_01968 9.5e-107 cwlO M NlpC/P60 family
PHLHKCMP_01969 1.4e-13 cwlO M NlpC/P60 family
PHLHKCMP_01970 1e-47 K sequence-specific DNA binding
PHLHKCMP_01971 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
PHLHKCMP_01972 3e-137 pbpX V Beta-lactamase
PHLHKCMP_01973 2.9e-19 pbpX V Beta-lactamase
PHLHKCMP_01974 1.7e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PHLHKCMP_01975 3.5e-187 yueF S AI-2E family transporter
PHLHKCMP_01976 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
PHLHKCMP_01977 6.9e-203 gntP EG Gluconate
PHLHKCMP_01978 6.7e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
PHLHKCMP_01979 1.9e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
PHLHKCMP_01980 6.3e-254 gor 1.8.1.7 C Glutathione reductase
PHLHKCMP_01981 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PHLHKCMP_01982 1.9e-26
PHLHKCMP_01983 9.4e-197 M MucBP domain
PHLHKCMP_01984 1.3e-159 lysR5 K LysR substrate binding domain
PHLHKCMP_01985 8.8e-124 yxaA S membrane transporter protein
PHLHKCMP_01986 3.2e-57 ywjH S Protein of unknown function (DUF1634)
PHLHKCMP_01987 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PHLHKCMP_01988 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PHLHKCMP_01989 2.7e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PHLHKCMP_01990 2.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
PHLHKCMP_01991 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
PHLHKCMP_01992 1.4e-178 glk 2.7.1.2 G Glucokinase
PHLHKCMP_01993 1.3e-108 pepE 3.4.13.21 E Belongs to the peptidase S51 family
PHLHKCMP_01994 2.2e-67 yqhL P Rhodanese-like protein
PHLHKCMP_01995 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
PHLHKCMP_01996 6.4e-139 glpQ 3.1.4.46 C phosphodiesterase
PHLHKCMP_01997 4.1e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PHLHKCMP_01998 1.3e-63 glnR K Transcriptional regulator
PHLHKCMP_01999 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
PHLHKCMP_02000 6.9e-162
PHLHKCMP_02001 8.8e-181
PHLHKCMP_02002 5.3e-98 dut S Protein conserved in bacteria
PHLHKCMP_02003 5.3e-56
PHLHKCMP_02004 1.7e-30
PHLHKCMP_02007 5.4e-19
PHLHKCMP_02008 5.2e-89 K Transcriptional regulator
PHLHKCMP_02009 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PHLHKCMP_02010 3.5e-52 ysxB J Cysteine protease Prp
PHLHKCMP_02011 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PHLHKCMP_02012 1.3e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PHLHKCMP_02013 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHLHKCMP_02014 1.3e-73 yqhY S Asp23 family, cell envelope-related function
PHLHKCMP_02015 5.8e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PHLHKCMP_02016 1.9e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PHLHKCMP_02017 9.3e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHLHKCMP_02018 1.3e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHLHKCMP_02019 8.3e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PHLHKCMP_02020 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PHLHKCMP_02021 2.2e-76 argR K Regulates arginine biosynthesis genes
PHLHKCMP_02022 2.7e-305 recN L May be involved in recombinational repair of damaged DNA
PHLHKCMP_02023 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
PHLHKCMP_02024 1.2e-104 opuCB E ABC transporter permease
PHLHKCMP_02025 3.9e-173 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PHLHKCMP_02026 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
PHLHKCMP_02027 1.7e-54
PHLHKCMP_02028 4.8e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PHLHKCMP_02029 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PHLHKCMP_02030 6.3e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PHLHKCMP_02031 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PHLHKCMP_02032 6.1e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PHLHKCMP_02033 7.1e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PHLHKCMP_02034 1.7e-134 stp 3.1.3.16 T phosphatase
PHLHKCMP_02035 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PHLHKCMP_02036 4.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PHLHKCMP_02037 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PHLHKCMP_02038 5.8e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
PHLHKCMP_02039 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PHLHKCMP_02040 1.8e-57 asp S Asp23 family, cell envelope-related function
PHLHKCMP_02041 6.1e-310 yloV S DAK2 domain fusion protein YloV
PHLHKCMP_02042 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PHLHKCMP_02043 4.3e-189 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PHLHKCMP_02044 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHLHKCMP_02045 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PHLHKCMP_02046 0.0 smc D Required for chromosome condensation and partitioning
PHLHKCMP_02047 6.6e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PHLHKCMP_02048 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PHLHKCMP_02049 6.6e-220 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PHLHKCMP_02050 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PHLHKCMP_02051 2.6e-39 ylqC S Belongs to the UPF0109 family
PHLHKCMP_02052 4.1e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PHLHKCMP_02053 7.6e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PHLHKCMP_02054 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PHLHKCMP_02055 8.4e-51
PHLHKCMP_02056 1.1e-64 3.1.3.102, 3.1.3.104 S hydrolase
PHLHKCMP_02057 1.9e-305 ybiT S ABC transporter, ATP-binding protein
PHLHKCMP_02058 4.9e-221 S CAAX protease self-immunity
PHLHKCMP_02059 3.5e-133 2.7.1.89 M Phosphotransferase enzyme family
PHLHKCMP_02060 1.4e-95 2.3.1.128 J Acetyltransferase (GNAT) domain
PHLHKCMP_02061 2.6e-97 speG J Acetyltransferase (GNAT) domain
PHLHKCMP_02062 2.1e-142 endA F DNA RNA non-specific endonuclease
PHLHKCMP_02063 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
PHLHKCMP_02064 2.1e-58 K Transcriptional regulator (TetR family)
PHLHKCMP_02065 2e-196 yhgE V domain protein
PHLHKCMP_02066 1.4e-08
PHLHKCMP_02069 5.3e-243 EGP Major facilitator Superfamily
PHLHKCMP_02070 0.0 mdlA V ABC transporter
PHLHKCMP_02071 3.2e-50 mdlB V ABC transporter
PHLHKCMP_02072 2.3e-273 mdlB V ABC transporter
PHLHKCMP_02074 4.1e-192 C Aldo/keto reductase family
PHLHKCMP_02075 1.9e-102 M Protein of unknown function (DUF3737)
PHLHKCMP_02076 1.1e-220 patB 4.4.1.8 E Aminotransferase, class I
PHLHKCMP_02077 2.5e-101 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PHLHKCMP_02078 1.3e-69 S WxL domain surface cell wall-binding
PHLHKCMP_02079 5.4e-97 S WxL domain surface cell wall-binding
PHLHKCMP_02080 8.2e-166 S Fn3-like domain
PHLHKCMP_02081 1.8e-60
PHLHKCMP_02082 1.3e-82
PHLHKCMP_02083 9.4e-287
PHLHKCMP_02084 5.1e-60
PHLHKCMP_02085 1.3e-21 npr 1.11.1.1 C NADH oxidase
PHLHKCMP_02086 2.2e-175 npr 1.11.1.1 C NADH oxidase
PHLHKCMP_02087 1.8e-110 K Bacterial regulatory proteins, tetR family
PHLHKCMP_02088 2.3e-116 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PHLHKCMP_02089 3.2e-106
PHLHKCMP_02090 2.3e-20 GBS0088 S Nucleotidyltransferase
PHLHKCMP_02091 1.3e-47 GBS0088 S Nucleotidyltransferase
PHLHKCMP_02092 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PHLHKCMP_02093 1.9e-220 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PHLHKCMP_02094 8e-87 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
PHLHKCMP_02095 4.1e-171 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PHLHKCMP_02096 0.0 S membrane
PHLHKCMP_02097 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PHLHKCMP_02098 2.3e-51 ykoT GT2 M Glycosyl transferase family 2
PHLHKCMP_02099 2.5e-112 ykoT GT2 M Glycosyl transferase family 2
PHLHKCMP_02100 5.1e-265 mutS L MutS domain V
PHLHKCMP_02101 3.9e-271 mutS L ATPase domain of DNA mismatch repair MUTS family
PHLHKCMP_02102 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHLHKCMP_02103 1.9e-222 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHLHKCMP_02104 1.2e-168 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PHLHKCMP_02105 3e-125 C Enoyl-(Acyl carrier protein) reductase
PHLHKCMP_02106 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PHLHKCMP_02107 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PHLHKCMP_02108 1.2e-68 yqeY S YqeY-like protein
PHLHKCMP_02109 5.8e-180 phoH T phosphate starvation-inducible protein PhoH
PHLHKCMP_02110 3.6e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PHLHKCMP_02111 1.5e-71 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PHLHKCMP_02112 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PHLHKCMP_02113 6.9e-147 recO L Involved in DNA repair and RecF pathway recombination
PHLHKCMP_02114 5.8e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PHLHKCMP_02115 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PHLHKCMP_02116 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PHLHKCMP_02117 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PHLHKCMP_02118 2.8e-64 K helix_turn_helix gluconate operon transcriptional repressor
PHLHKCMP_02119 3.6e-160 ytrB V ABC transporter, ATP-binding protein
PHLHKCMP_02120 8.9e-198
PHLHKCMP_02121 7.7e-194
PHLHKCMP_02122 6e-124 S ABC-2 family transporter protein
PHLHKCMP_02123 2.3e-52 V ABC transporter, ATP-binding protein
PHLHKCMP_02124 1e-99 V ABC transporter, ATP-binding protein
PHLHKCMP_02125 7.7e-157 dkgB S reductase
PHLHKCMP_02126 1.4e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PHLHKCMP_02127 1.2e-100 S ABC transporter permease
PHLHKCMP_02128 2.4e-259 P ABC transporter
PHLHKCMP_02129 8.4e-114 P cobalt transport
PHLHKCMP_02130 1.2e-251 S ATPases associated with a variety of cellular activities
PHLHKCMP_02131 1.4e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHLHKCMP_02132 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHLHKCMP_02134 1.3e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHLHKCMP_02135 1.3e-162 FbpA K Domain of unknown function (DUF814)
PHLHKCMP_02136 5.7e-55 S Domain of unknown function (DU1801)
PHLHKCMP_02137 4.9e-34
PHLHKCMP_02138 5e-179 yghZ C Aldo keto reductase family protein
PHLHKCMP_02139 4.3e-112 pgm1 G phosphoglycerate mutase
PHLHKCMP_02140 6e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PHLHKCMP_02141 3.9e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHLHKCMP_02142 8.5e-78 yiaC K Acetyltransferase (GNAT) domain
PHLHKCMP_02143 1e-309 oppA E ABC transporter, substratebinding protein
PHLHKCMP_02144 2.3e-268 oppA E ABC transporter, substratebinding protein
PHLHKCMP_02145 2.1e-157 hipB K Helix-turn-helix
PHLHKCMP_02147 0.0 3.6.4.13 M domain protein
PHLHKCMP_02148 8.6e-28 zmp2 O Zinc-dependent metalloprotease
PHLHKCMP_02149 7.4e-65 zmp2 O Zinc-dependent metalloprotease
PHLHKCMP_02150 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
PHLHKCMP_02151 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PHLHKCMP_02152 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
PHLHKCMP_02153 2.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PHLHKCMP_02154 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PHLHKCMP_02155 3.7e-205 yacL S domain protein
PHLHKCMP_02156 1.3e-287 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PHLHKCMP_02157 3.3e-269 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PHLHKCMP_02158 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PHLHKCMP_02159 9.7e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHLHKCMP_02160 2.2e-96 yacP S YacP-like NYN domain
PHLHKCMP_02161 2.9e-99 sigH K Sigma-70 region 2
PHLHKCMP_02162 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PHLHKCMP_02163 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PHLHKCMP_02164 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
PHLHKCMP_02165 9.7e-158 S Alpha/beta hydrolase of unknown function (DUF915)
PHLHKCMP_02166 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PHLHKCMP_02167 1.1e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PHLHKCMP_02168 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PHLHKCMP_02169 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PHLHKCMP_02170 5.6e-217 L Belongs to the 'phage' integrase family
PHLHKCMP_02176 3.6e-25 S Pfam:Peptidase_M78
PHLHKCMP_02177 4.6e-24 K Helix-turn-helix
PHLHKCMP_02180 9.8e-152 S hydrolase
PHLHKCMP_02181 8.2e-177 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PHLHKCMP_02182 8.3e-152 EG EamA-like transporter family
PHLHKCMP_02183 2.5e-175 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PHLHKCMP_02184 2.3e-99 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PHLHKCMP_02185 3.8e-232
PHLHKCMP_02186 9.4e-77 fld C Flavodoxin
PHLHKCMP_02187 0.0 M Bacterial Ig-like domain (group 3)
PHLHKCMP_02188 1.2e-277 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
PHLHKCMP_02189 2.3e-147 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
PHLHKCMP_02190 7.8e-32
PHLHKCMP_02191 8.6e-126 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
PHLHKCMP_02192 4.1e-14 ycaM E amino acid
PHLHKCMP_02193 1.4e-237 ycaM E amino acid
PHLHKCMP_02194 1.1e-77 K Winged helix DNA-binding domain
PHLHKCMP_02195 3.6e-165 S Oxidoreductase, aldo keto reductase family protein
PHLHKCMP_02196 3.7e-162 akr5f 1.1.1.346 S reductase
PHLHKCMP_02197 6.6e-162 K Transcriptional regulator
PHLHKCMP_02199 9.1e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
PHLHKCMP_02200 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PHLHKCMP_02201 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PHLHKCMP_02202 9.8e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PHLHKCMP_02203 9.2e-275 cydA 1.10.3.14 C ubiquinol oxidase
PHLHKCMP_02204 2.4e-211 S Alpha beta
PHLHKCMP_02205 4.2e-81 S Alpha beta
PHLHKCMP_02206 1.8e-23
PHLHKCMP_02207 2e-98 S ECF transporter, substrate-specific component
PHLHKCMP_02208 4.1e-50 yfnA E Amino Acid
PHLHKCMP_02209 1.9e-187 yfnA E Amino Acid
PHLHKCMP_02210 4e-165 mleP S Sodium Bile acid symporter family
PHLHKCMP_02211 3.6e-307 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PHLHKCMP_02212 8.4e-165 mleR K LysR family
PHLHKCMP_02213 5.5e-161 mleR K LysR family transcriptional regulator
PHLHKCMP_02214 3.6e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PHLHKCMP_02215 1.6e-263 frdC 1.3.5.4 C FAD binding domain
PHLHKCMP_02216 2.1e-255 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PHLHKCMP_02217 9.2e-26 S AAA domain, putative AbiEii toxin, Type IV TA system
PHLHKCMP_02219 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PHLHKCMP_02220 3.4e-172 htrA 3.4.21.107 O serine protease
PHLHKCMP_02221 5.8e-157 vicX 3.1.26.11 S domain protein
PHLHKCMP_02222 3.8e-151 yycI S YycH protein
PHLHKCMP_02223 2.3e-243 yycH S YycH protein
PHLHKCMP_02224 0.0 vicK 2.7.13.3 T Histidine kinase
PHLHKCMP_02225 1.4e-130 K response regulator
PHLHKCMP_02227 8e-38 Q ubiE/COQ5 methyltransferase family
PHLHKCMP_02228 1.5e-48
PHLHKCMP_02229 2.1e-36 S Phage gp6-like head-tail connector protein
PHLHKCMP_02232 2.4e-268 S Caudovirus prohead serine protease
PHLHKCMP_02233 9.2e-187 S Phage portal protein
PHLHKCMP_02235 6.3e-66 terL S overlaps another CDS with the same product name
PHLHKCMP_02236 2.1e-249 terL S overlaps another CDS with the same product name
PHLHKCMP_02237 5.7e-80 terS L overlaps another CDS with the same product name
PHLHKCMP_02238 1e-66 L HNH endonuclease
PHLHKCMP_02239 2.3e-46 S head-tail joining protein
PHLHKCMP_02240 8.9e-24
PHLHKCMP_02241 5.2e-81
PHLHKCMP_02242 7.9e-263 S Virulence-associated protein E
PHLHKCMP_02243 4.6e-135 L DNA replication protein
PHLHKCMP_02244 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
PHLHKCMP_02245 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
PHLHKCMP_02246 6.8e-60
PHLHKCMP_02247 1.7e-73
PHLHKCMP_02248 5.5e-81 yybC S Protein of unknown function (DUF2798)
PHLHKCMP_02249 5.9e-43
PHLHKCMP_02250 6.8e-47
PHLHKCMP_02251 1.3e-204 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PHLHKCMP_02252 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
PHLHKCMP_02253 2.4e-144 yjfP S Dienelactone hydrolase family
PHLHKCMP_02254 1.1e-43
PHLHKCMP_02255 1.5e-65 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PHLHKCMP_02256 1.5e-255 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PHLHKCMP_02257 5.9e-48
PHLHKCMP_02258 3.3e-56
PHLHKCMP_02260 3.7e-162
PHLHKCMP_02261 1.3e-72 K Transcriptional regulator
PHLHKCMP_02262 0.0 pepF2 E Oligopeptidase F
PHLHKCMP_02263 8.5e-173 D Alpha beta
PHLHKCMP_02264 8.7e-44 S Enterocin A Immunity
PHLHKCMP_02265 3.6e-64 yvoA_1 K Transcriptional regulator, GntR family
PHLHKCMP_02266 5.1e-125 skfE V ABC transporter
PHLHKCMP_02267 2.7e-132
PHLHKCMP_02268 3.7e-107 pncA Q Isochorismatase family
PHLHKCMP_02269 2.5e-225 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PHLHKCMP_02270 0.0 sbcC L Putative exonuclease SbcCD, C subunit
PHLHKCMP_02271 2.4e-170 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PHLHKCMP_02272 1.2e-305 arlS 2.7.13.3 T Histidine kinase
PHLHKCMP_02273 5.6e-121 K response regulator
PHLHKCMP_02274 4.3e-242 rarA L recombination factor protein RarA
PHLHKCMP_02275 3e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PHLHKCMP_02276 8.1e-13 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PHLHKCMP_02277 2.9e-126 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PHLHKCMP_02278 1.4e-72 S Peptidase propeptide and YPEB domain
PHLHKCMP_02279 1.6e-97 yceD S Uncharacterized ACR, COG1399
PHLHKCMP_02280 7.5e-219 ylbM S Belongs to the UPF0348 family
PHLHKCMP_02281 1.3e-139 yqeM Q Methyltransferase
PHLHKCMP_02282 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PHLHKCMP_02283 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PHLHKCMP_02284 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PHLHKCMP_02285 1.1e-50 yhbY J RNA-binding protein
PHLHKCMP_02286 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
PHLHKCMP_02287 1.4e-98 yqeG S HAD phosphatase, family IIIA
PHLHKCMP_02288 5.7e-138 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
PHLHKCMP_02289 4.8e-40
PHLHKCMP_02290 5.1e-128 cbiO P ABC transporter
PHLHKCMP_02291 2.3e-145 P Cobalt transport protein
PHLHKCMP_02292 1.8e-181 nikMN P PDGLE domain
PHLHKCMP_02293 2e-39 K Crp-like helix-turn-helix domain
PHLHKCMP_02294 3.2e-47 K Crp-like helix-turn-helix domain
PHLHKCMP_02295 3.5e-241 larA 5.1.2.1 S Domain of unknown function (DUF2088)
PHLHKCMP_02296 4.1e-125 larB S AIR carboxylase
PHLHKCMP_02297 1.5e-130 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PHLHKCMP_02298 1.1e-66 larC 4.99.1.12 S Protein of unknown function DUF111
PHLHKCMP_02299 4.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PHLHKCMP_02300 9.1e-150 larE S NAD synthase
PHLHKCMP_02301 2.1e-177 1.6.5.5 C Zinc-binding dehydrogenase
PHLHKCMP_02302 3.8e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PHLHKCMP_02303 5e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PHLHKCMP_02304 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PHLHKCMP_02305 8.4e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
PHLHKCMP_02306 1.9e-135 S peptidase C26
PHLHKCMP_02307 1.7e-201 L HIRAN domain
PHLHKCMP_02308 4.9e-90 L HIRAN domain
PHLHKCMP_02309 9.9e-85 F NUDIX domain
PHLHKCMP_02310 2.6e-250 yifK E Amino acid permease
PHLHKCMP_02311 2e-121
PHLHKCMP_02312 2.8e-148 ydjP I Alpha/beta hydrolase family
PHLHKCMP_02313 1.7e-08 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PHLHKCMP_02314 2.4e-102 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PHLHKCMP_02315 3.8e-278 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PHLHKCMP_02316 4.5e-180 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PHLHKCMP_02317 7.3e-107 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHLHKCMP_02318 4.1e-47 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHLHKCMP_02319 2.5e-97 S CRISPR-associated protein (Cas_Csn2)
PHLHKCMP_02320 0.0 pacL1 P P-type ATPase
PHLHKCMP_02321 2e-132 2.4.2.3 F Phosphorylase superfamily
PHLHKCMP_02322 1.6e-28 KT PspC domain
PHLHKCMP_02323 4.3e-109 S NADPH-dependent FMN reductase
PHLHKCMP_02324 1.1e-75 papX3 K Transcriptional regulator
PHLHKCMP_02325 1.3e-72 hsp1 O Belongs to the small heat shock protein (HSP20) family
PHLHKCMP_02326 4.2e-80 S Protein of unknown function (DUF3021)
PHLHKCMP_02327 8.7e-66 K LytTr DNA-binding domain
PHLHKCMP_02328 2.3e-226 mdtG EGP Major facilitator Superfamily
PHLHKCMP_02329 3.3e-50 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
PHLHKCMP_02330 1.3e-213 yeaN P Transporter, major facilitator family protein
PHLHKCMP_02331 5.8e-126 S reductase
PHLHKCMP_02332 1.2e-165 1.1.1.65 C Aldo keto reductase
PHLHKCMP_02333 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
PHLHKCMP_02334 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
PHLHKCMP_02335 3.6e-11
PHLHKCMP_02336 5.1e-27
PHLHKCMP_02337 7.3e-254
PHLHKCMP_02338 7.5e-208 C Oxidoreductase
PHLHKCMP_02339 5.4e-150 cbiQ P cobalt transport
PHLHKCMP_02340 0.0 ykoD P ABC transporter, ATP-binding protein
PHLHKCMP_02341 5.5e-98 S UPF0397 protein
PHLHKCMP_02343 1.6e-129 K UbiC transcription regulator-associated domain protein
PHLHKCMP_02344 1.8e-53 K Transcriptional regulator PadR-like family
PHLHKCMP_02345 8.6e-142
PHLHKCMP_02346 1.3e-148
PHLHKCMP_02347 3.4e-88
PHLHKCMP_02348 5.1e-65 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
PHLHKCMP_02349 1.2e-52 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
PHLHKCMP_02350 1.1e-105 yjjC V ABC transporter
PHLHKCMP_02351 1.2e-52 yjjC V ABC transporter
PHLHKCMP_02352 2.7e-80 M Exporter of polyketide antibiotics
PHLHKCMP_02353 1.1e-121 M Exporter of polyketide antibiotics
PHLHKCMP_02354 9e-116 K Transcriptional regulator
PHLHKCMP_02355 3.8e-274 C Electron transfer flavoprotein FAD-binding domain
PHLHKCMP_02356 4.8e-262 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
PHLHKCMP_02357 1.5e-163 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
PHLHKCMP_02358 1.1e-183 D Alpha beta
PHLHKCMP_02359 6.6e-196 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PHLHKCMP_02360 4.2e-77 gor 1.8.1.7 C Glutathione reductase
PHLHKCMP_02361 1.7e-159 gor 1.8.1.7 C Glutathione reductase
PHLHKCMP_02362 2.4e-53 S Enterocin A Immunity
PHLHKCMP_02363 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PHLHKCMP_02364 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PHLHKCMP_02365 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHLHKCMP_02366 1.6e-142 oppF E Oligopeptide/dipeptide transporter, C-terminal region
PHLHKCMP_02367 1.9e-187 oppD P Belongs to the ABC transporter superfamily
PHLHKCMP_02368 4e-157 amiD EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHLHKCMP_02369 1.3e-216 amiC U Binding-protein-dependent transport system inner membrane component
PHLHKCMP_02370 1.7e-31 amiC U Binding-protein-dependent transport system inner membrane component
PHLHKCMP_02371 4.5e-215 amiA E Bacterial extracellular solute-binding proteins, family 5 Middle
PHLHKCMP_02372 1e-76 amiA E Bacterial extracellular solute-binding proteins, family 5 Middle
PHLHKCMP_02373 6.8e-13 amiA E Bacterial extracellular solute-binding proteins, family 5 Middle
PHLHKCMP_02374 4.4e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
PHLHKCMP_02375 5.3e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHLHKCMP_02377 1.5e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PHLHKCMP_02378 5.6e-186 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHLHKCMP_02379 3.5e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PHLHKCMP_02380 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PHLHKCMP_02381 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PHLHKCMP_02382 3e-251 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PHLHKCMP_02383 3.1e-74 yabR J RNA binding
PHLHKCMP_02384 3.1e-63 divIC D Septum formation initiator
PHLHKCMP_02386 2.2e-42 yabO J S4 domain protein
PHLHKCMP_02387 3.3e-289 yabM S Polysaccharide biosynthesis protein
PHLHKCMP_02388 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PHLHKCMP_02389 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PHLHKCMP_02390 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PHLHKCMP_02391 2.8e-260 S Putative peptidoglycan binding domain
PHLHKCMP_02392 2.1e-114 S (CBS) domain
PHLHKCMP_02393 4.1e-84 S QueT transporter
PHLHKCMP_02394 2e-255 npr 1.11.1.1 C NADH oxidase
PHLHKCMP_02395 4.1e-136 XK27_08845 S ABC transporter, ATP-binding protein
PHLHKCMP_02396 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PHLHKCMP_02397 1.5e-175 XK27_08835 S ABC transporter
PHLHKCMP_02398 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PHLHKCMP_02399 7.5e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PHLHKCMP_02400 1.8e-229 hom1 1.1.1.3 E Homoserine dehydrogenase
PHLHKCMP_02401 6.2e-160 degV S Uncharacterised protein, DegV family COG1307
PHLHKCMP_02402 1.5e-188 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PHLHKCMP_02403 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
PHLHKCMP_02404 5.6e-37
PHLHKCMP_02405 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PHLHKCMP_02406 4.4e-106 3.2.2.20 K acetyltransferase
PHLHKCMP_02407 3e-295 S ABC transporter, ATP-binding protein
PHLHKCMP_02408 8e-108 2.7.7.65 T diguanylate cyclase
PHLHKCMP_02409 2.3e-126 EGP Major facilitator Superfamily
PHLHKCMP_02410 1.7e-94 EG EamA-like transporter family
PHLHKCMP_02411 2.3e-25 EG EamA-like transporter family
PHLHKCMP_02412 3.8e-78 S Protein of unknown function
PHLHKCMP_02413 2.9e-30 S Protein of unknown function
PHLHKCMP_02414 0.0 tetP J elongation factor G
PHLHKCMP_02415 1.8e-116 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PHLHKCMP_02416 7.8e-160 yobV1 K WYL domain
PHLHKCMP_02417 9.3e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
PHLHKCMP_02418 2.9e-81 6.3.3.2 S ASCH
PHLHKCMP_02419 1.4e-224 1.14.14.9 Q 4-hydroxyphenylacetate
PHLHKCMP_02420 2.5e-124 wzb 3.1.3.48 T Tyrosine phosphatase family
PHLHKCMP_02421 1.5e-247 yjjP S Putative threonine/serine exporter
PHLHKCMP_02422 2.7e-188 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PHLHKCMP_02423 4.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PHLHKCMP_02425 2e-288 QT PucR C-terminal helix-turn-helix domain
PHLHKCMP_02426 4.8e-122 drgA C Nitroreductase family
PHLHKCMP_02427 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
PHLHKCMP_02428 2.6e-163 ptlF S KR domain
PHLHKCMP_02429 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHLHKCMP_02430 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHLHKCMP_02431 9.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PHLHKCMP_02432 7.1e-169 lacX 5.1.3.3 G Aldose 1-epimerase
PHLHKCMP_02433 6.6e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PHLHKCMP_02434 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PHLHKCMP_02435 3.4e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
PHLHKCMP_02436 2.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PHLHKCMP_02437 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PHLHKCMP_02438 1.8e-156 dprA LU DNA protecting protein DprA
PHLHKCMP_02439 2.1e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHLHKCMP_02440 3.1e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PHLHKCMP_02442 1.4e-228 XK27_05470 E Methionine synthase
PHLHKCMP_02443 4.3e-172 cpsY K Transcriptional regulator, LysR family
PHLHKCMP_02444 1.3e-20 EGP Major facilitator Superfamily
PHLHKCMP_02445 2.3e-78 uspA T universal stress protein
PHLHKCMP_02446 2.8e-152 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PHLHKCMP_02448 1.7e-16
PHLHKCMP_02449 7.1e-44 S zinc-ribbon domain
PHLHKCMP_02450 7.6e-75 S response to antibiotic
PHLHKCMP_02451 1.7e-48 K Cro/C1-type HTH DNA-binding domain
PHLHKCMP_02452 3.3e-21 S Protein of unknown function (DUF2929)
PHLHKCMP_02453 2.7e-224 lsgC M Glycosyl transferases group 1
PHLHKCMP_02454 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PHLHKCMP_02455 5.1e-164 S Putative esterase
PHLHKCMP_02456 2.4e-130 gntR2 K Transcriptional regulator
PHLHKCMP_02457 4.5e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PHLHKCMP_02458 4.4e-138
PHLHKCMP_02459 1.5e-115 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PHLHKCMP_02460 1.4e-136 rrp8 K LytTr DNA-binding domain
PHLHKCMP_02461 2.7e-91 M1-874 K Domain of unknown function (DUF1836)
PHLHKCMP_02462 8.5e-60
PHLHKCMP_02463 1e-72 hspX O Belongs to the small heat shock protein (HSP20) family
PHLHKCMP_02464 4.4e-58
PHLHKCMP_02465 2.3e-238 yhdP S Transporter associated domain
PHLHKCMP_02467 1.8e-127 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHLHKCMP_02468 1.6e-64 K helix_turn_helix, mercury resistance
PHLHKCMP_02469 6.2e-114 GM NAD(P)H-binding
PHLHKCMP_02470 2.8e-155 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PHLHKCMP_02471 1.9e-147 S Sucrose-6F-phosphate phosphohydrolase
PHLHKCMP_02472 2e-106
PHLHKCMP_02473 1.9e-223 pltK 2.7.13.3 T GHKL domain
PHLHKCMP_02474 1.6e-137 pltR K LytTr DNA-binding domain
PHLHKCMP_02475 1e-54
PHLHKCMP_02476 2.5e-59
PHLHKCMP_02477 2e-110 S CAAX protease self-immunity
PHLHKCMP_02478 3.5e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
PHLHKCMP_02479 1.3e-87
PHLHKCMP_02480 2.5e-46
PHLHKCMP_02481 0.0 uvrA2 L ABC transporter
PHLHKCMP_02483 9.9e-70 int L Belongs to the 'phage' integrase family
PHLHKCMP_02491 8.9e-37 S Pfam:Peptidase_M78
PHLHKCMP_02492 1.4e-21 K Transcriptional regulator, Cro CI family
PHLHKCMP_02493 5.4e-32 S Phage minor structural protein
PHLHKCMP_02494 7.9e-187 S Prophage endopeptidase tail
PHLHKCMP_02495 1.6e-146 S Phage tail protein
PHLHKCMP_02496 0.0 D NLP P60 protein
PHLHKCMP_02497 7.5e-43 S Phage tail assembly chaperone proteins, TAC
PHLHKCMP_02499 1.5e-104 S Phage tail tube protein
PHLHKCMP_02500 4.2e-49 S Protein of unknown function (DUF806)
PHLHKCMP_02501 6.4e-64 S Bacteriophage HK97-gp10, putative tail-component
PHLHKCMP_02502 7.4e-53 S Phage head-tail joining protein
PHLHKCMP_02503 1e-35
PHLHKCMP_02504 1.9e-104 S Phage capsid family
PHLHKCMP_02505 1.7e-105 S Caudovirus prohead serine protease
PHLHKCMP_02506 1.1e-193 S Phage portal protein
PHLHKCMP_02508 0.0 S Phage Terminase
PHLHKCMP_02509 5.1e-59 L Phage terminase small Subunit
PHLHKCMP_02510 6.6e-95 V HNH nucleases
PHLHKCMP_02513 1.5e-26
PHLHKCMP_02514 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PHLHKCMP_02515 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
PHLHKCMP_02516 4.3e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PHLHKCMP_02517 1.1e-151 ywkB S Membrane transport protein
PHLHKCMP_02518 5.2e-164 yvgN C Aldo keto reductase
PHLHKCMP_02519 2e-132 thrE S Putative threonine/serine exporter
PHLHKCMP_02520 2e-77 S Threonine/Serine exporter, ThrE
PHLHKCMP_02521 2.3e-43 S Protein of unknown function (DUF1093)
PHLHKCMP_02522 2.7e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PHLHKCMP_02523 2.7e-91 ymdB S Macro domain protein
PHLHKCMP_02524 1.2e-95 K transcriptional regulator
PHLHKCMP_02525 5.5e-50 yvlA
PHLHKCMP_02526 2.3e-160 ypuA S Protein of unknown function (DUF1002)
PHLHKCMP_02527 0.0
PHLHKCMP_02528 4.9e-185 S Bacterial protein of unknown function (DUF916)
PHLHKCMP_02529 4.1e-11 arpU S Phage transcriptional regulator, ArpU family
PHLHKCMP_02534 9.5e-17 V HNH nucleases
PHLHKCMP_02535 5e-28
PHLHKCMP_02536 1.1e-55 S Terminase small subunit
PHLHKCMP_02537 4.9e-251 S Phage terminase, large subunit
PHLHKCMP_02538 6.8e-287 S Phage portal protein, SPP1 Gp6-like
PHLHKCMP_02539 3.7e-163 S Phage Mu protein F like protein
PHLHKCMP_02540 5.1e-63 S Domain of unknown function (DUF4355)
PHLHKCMP_02541 3.6e-199 gpG
PHLHKCMP_02542 1.5e-59 S Phage gp6-like head-tail connector protein
PHLHKCMP_02543 2e-51
PHLHKCMP_02544 3.8e-91
PHLHKCMP_02545 6.3e-61
PHLHKCMP_02546 3.1e-91
PHLHKCMP_02547 8.3e-85 S Phage tail assembly chaperone protein, TAC
PHLHKCMP_02549 0.0 D NLP P60 protein
PHLHKCMP_02550 8e-160 S Phage tail protein
PHLHKCMP_02551 2.9e-194 3.4.14.13 M Prophage endopeptidase tail
PHLHKCMP_02553 1.5e-49
PHLHKCMP_02554 7.1e-245 S Putative metallopeptidase domain
PHLHKCMP_02555 2.4e-220 3.1.3.1 S associated with various cellular activities
PHLHKCMP_02556 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
PHLHKCMP_02557 0.0 ubiB S ABC1 family
PHLHKCMP_02558 3.4e-17 brnQ U Component of the transport system for branched-chain amino acids
PHLHKCMP_02559 1.2e-214 brnQ U Component of the transport system for branched-chain amino acids
PHLHKCMP_02560 0.0 lacS G Transporter
PHLHKCMP_02561 0.0 lacA 3.2.1.23 G -beta-galactosidase
PHLHKCMP_02562 1.3e-187 lacR K Transcriptional regulator
PHLHKCMP_02563 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PHLHKCMP_02564 1.1e-229 mdtH P Sugar (and other) transporter
PHLHKCMP_02565 1.6e-304 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PHLHKCMP_02566 8.6e-232 EGP Major facilitator Superfamily
PHLHKCMP_02567 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
PHLHKCMP_02568 4.5e-106 fic D Fic/DOC family
PHLHKCMP_02569 1.5e-74 K Helix-turn-helix XRE-family like proteins
PHLHKCMP_02570 3.7e-182 galR K Transcriptional regulator
PHLHKCMP_02571 7.2e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PHLHKCMP_02572 8.9e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PHLHKCMP_02573 6e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PHLHKCMP_02574 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PHLHKCMP_02575 1.9e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
PHLHKCMP_02576 0.0 rafA 3.2.1.22 G alpha-galactosidase
PHLHKCMP_02577 0.0 lacS G Transporter
PHLHKCMP_02578 3e-10 lacS G Transporter
PHLHKCMP_02579 8.5e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PHLHKCMP_02580 5.4e-173 galR K Transcriptional regulator
PHLHKCMP_02581 8.2e-193 C Aldo keto reductase family protein
PHLHKCMP_02582 5.2e-60 S pyridoxamine 5-phosphate
PHLHKCMP_02583 0.0 1.3.5.4 C FAD binding domain
PHLHKCMP_02584 1.8e-178 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHLHKCMP_02585 2.7e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PHLHKCMP_02586 4.3e-166 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PHLHKCMP_02587 5.9e-174 K Transcriptional regulator, LysR family
PHLHKCMP_02588 1.1e-218 ydiN EGP Major Facilitator Superfamily
PHLHKCMP_02589 1.4e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PHLHKCMP_02590 1.1e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PHLHKCMP_02591 1e-156 IQ Enoyl-(Acyl carrier protein) reductase
PHLHKCMP_02592 2.1e-165 G Xylose isomerase-like TIM barrel
PHLHKCMP_02593 4.7e-168 K Transcriptional regulator, LysR family
PHLHKCMP_02594 2.8e-200 EGP Major Facilitator Superfamily
PHLHKCMP_02595 1e-63
PHLHKCMP_02596 9.4e-126 estA S Putative esterase
PHLHKCMP_02597 2.4e-16 estA S Putative esterase
PHLHKCMP_02598 2.2e-131 K UTRA domain
PHLHKCMP_02599 4.9e-246 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_02600 1.9e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PHLHKCMP_02601 3e-137 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
PHLHKCMP_02602 8.4e-212 S Bacterial protein of unknown function (DUF871)
PHLHKCMP_02603 1.4e-77 elaA S GNAT family
PHLHKCMP_02604 9.3e-74 K Transcriptional regulator
PHLHKCMP_02605 3.3e-225 ndh 1.6.99.3 C NADH dehydrogenase
PHLHKCMP_02606 1.2e-39
PHLHKCMP_02607 5.7e-205 potD P ABC transporter
PHLHKCMP_02608 2.9e-140 potC P ABC transporter permease
PHLHKCMP_02609 2.9e-148 potB P ABC transporter permease
PHLHKCMP_02610 3.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PHLHKCMP_02611 2.9e-96 puuR K Cupin domain
PHLHKCMP_02612 1.1e-83 6.3.3.2 S ASCH
PHLHKCMP_02613 8.7e-84 K GNAT family
PHLHKCMP_02614 1.8e-87 K acetyltransferase
PHLHKCMP_02615 1.5e-20
PHLHKCMP_02616 1.2e-55 ytrA K helix_turn_helix gluconate operon transcriptional repressor
PHLHKCMP_02617 1.3e-154 ytrB V ABC transporter
PHLHKCMP_02618 2e-108
PHLHKCMP_02619 8.1e-31
PHLHKCMP_02620 3.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
PHLHKCMP_02621 1.8e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PHLHKCMP_02623 2.6e-239 xylP1 G MFS/sugar transport protein
PHLHKCMP_02624 6.7e-122 qmcA O prohibitin homologues
PHLHKCMP_02625 3e-30
PHLHKCMP_02626 9.3e-278 bmr3 EGP Major facilitator Superfamily
PHLHKCMP_02627 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PHLHKCMP_02628 4.5e-121
PHLHKCMP_02629 2.5e-291 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
PHLHKCMP_02630 5e-165 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PHLHKCMP_02631 1.8e-254 mmuP E amino acid
PHLHKCMP_02632 3.5e-134 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PHLHKCMP_02633 1.2e-42 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PHLHKCMP_02634 6e-203 mntH P H( )-stimulated, divalent metal cation uptake system
PHLHKCMP_02636 1.6e-154 T Calcineurin-like phosphoesterase superfamily domain
PHLHKCMP_02637 4.4e-94 K Acetyltransferase (GNAT) domain
PHLHKCMP_02638 3.1e-95
PHLHKCMP_02639 1.5e-181 P secondary active sulfate transmembrane transporter activity
PHLHKCMP_02640 4.1e-90 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
PHLHKCMP_02646 5.1e-08
PHLHKCMP_02650 9.7e-155 glcU U sugar transport
PHLHKCMP_02651 3e-215 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
PHLHKCMP_02652 2.7e-285 yclK 2.7.13.3 T Histidine kinase
PHLHKCMP_02653 1.6e-134 K response regulator
PHLHKCMP_02654 3.9e-243 XK27_08635 S UPF0210 protein
PHLHKCMP_02655 2.3e-38 gcvR T Belongs to the UPF0237 family
PHLHKCMP_02656 1.3e-168 EG EamA-like transporter family
PHLHKCMP_02658 6.5e-91 S ECF-type riboflavin transporter, S component
PHLHKCMP_02659 8.6e-48
PHLHKCMP_02660 7e-212 yceI EGP Major facilitator Superfamily
PHLHKCMP_02661 9.4e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
PHLHKCMP_02662 1.9e-22
PHLHKCMP_02664 7.2e-158 S Alpha/beta hydrolase of unknown function (DUF915)
PHLHKCMP_02665 4.2e-169 ykfC 3.4.14.13 M NlpC/P60 family
PHLHKCMP_02666 8.6e-81 K AsnC family
PHLHKCMP_02667 2e-35
PHLHKCMP_02668 5.7e-33
PHLHKCMP_02669 2.4e-82 2.7.7.65 T diguanylate cyclase
PHLHKCMP_02670 3e-99 yobS K Bacterial regulatory proteins, tetR family
PHLHKCMP_02671 0.0 yfgQ P E1-E2 ATPase
PHLHKCMP_02672 1.1e-54 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_02673 2.2e-168 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_02674 6e-140 S Alpha/beta hydrolase of unknown function (DUF915)
PHLHKCMP_02675 2.3e-151 gntR K rpiR family
PHLHKCMP_02676 1.6e-143 lys M Glycosyl hydrolases family 25
PHLHKCMP_02677 1.1e-62 S Domain of unknown function (DUF4828)
PHLHKCMP_02678 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
PHLHKCMP_02679 3.5e-188 mocA S Oxidoreductase
PHLHKCMP_02680 1.8e-232 yfmL 3.6.4.13 L DEAD DEAH box helicase
PHLHKCMP_02682 8.7e-75 T Universal stress protein family
PHLHKCMP_02683 4.5e-244 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_02684 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
PHLHKCMP_02686 1.1e-72
PHLHKCMP_02687 1.2e-105
PHLHKCMP_02689 2.5e-167 ugpA U Binding-protein-dependent transport system inner membrane component
PHLHKCMP_02690 5.8e-141 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
PHLHKCMP_02691 2e-26 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
PHLHKCMP_02692 4.1e-84 uspA T Belongs to the universal stress protein A family
PHLHKCMP_02693 9.4e-272 pepV 3.5.1.18 E dipeptidase PepV
PHLHKCMP_02694 9.8e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PHLHKCMP_02695 8.7e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PHLHKCMP_02696 8.7e-301 ytgP S Polysaccharide biosynthesis protein
PHLHKCMP_02697 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PHLHKCMP_02698 1.7e-122 3.6.1.27 I Acid phosphatase homologues
PHLHKCMP_02699 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
PHLHKCMP_02700 4.2e-29
PHLHKCMP_02701 1e-295 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
PHLHKCMP_02702 3.1e-254 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
PHLHKCMP_02703 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHLHKCMP_02704 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
PHLHKCMP_02705 4.2e-225 patA 2.6.1.1 E Aminotransferase
PHLHKCMP_02706 8.1e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PHLHKCMP_02707 8.2e-188 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHLHKCMP_02708 7.7e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
PHLHKCMP_02709 7.4e-222 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PHLHKCMP_02710 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PHLHKCMP_02711 2.7e-39 ptsH G phosphocarrier protein HPR
PHLHKCMP_02712 6.5e-30
PHLHKCMP_02713 0.0 clpE O Belongs to the ClpA ClpB family
PHLHKCMP_02714 9.9e-97 L Integrase
PHLHKCMP_02715 1.8e-99 L Integrase
PHLHKCMP_02716 3.5e-80
PHLHKCMP_02718 8.7e-148 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PHLHKCMP_02719 6.1e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PHLHKCMP_02720 9.7e-106 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PHLHKCMP_02721 1.9e-224 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PHLHKCMP_02722 1.2e-72 rfbJ M Glycosyl transferase family 2
PHLHKCMP_02723 3.8e-64 rfbJ M Glycosyl transferase family 2
PHLHKCMP_02724 4.7e-138 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
PHLHKCMP_02725 1.4e-120 1.1.1.133 S Glycosyltransferase like family 2
PHLHKCMP_02726 3.4e-147 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PHLHKCMP_02727 9.3e-130 rgpB GT2 M Glycosyl transferase family 2
PHLHKCMP_02728 6.5e-88 welB S Glycosyltransferase like family 2
PHLHKCMP_02729 1.1e-78 S Glycosyl transferase family 2
PHLHKCMP_02730 3.2e-137 rfbN GT2 S Glycosyltransferase like family 2
PHLHKCMP_02731 4.7e-166 cps3F
PHLHKCMP_02733 2.3e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHLHKCMP_02734 2.5e-189 yegS 2.7.1.107 G Lipid kinase
PHLHKCMP_02735 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHLHKCMP_02736 2.7e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PHLHKCMP_02737 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHLHKCMP_02738 1.2e-198 camS S sex pheromone
PHLHKCMP_02739 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PHLHKCMP_02740 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PHLHKCMP_02741 7.1e-217 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PHLHKCMP_02742 1e-93 S UPF0316 protein
PHLHKCMP_02743 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PHLHKCMP_02744 7.6e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
PHLHKCMP_02745 1.7e-63 K Helix-turn-helix XRE-family like proteins
PHLHKCMP_02746 2.9e-47
PHLHKCMP_02748 2.6e-139 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
PHLHKCMP_02749 2.5e-101 K Transcriptional regulator, AbiEi antitoxin
PHLHKCMP_02751 1.1e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PHLHKCMP_02752 2.8e-179 coaA 2.7.1.33 F Pantothenic acid kinase
PHLHKCMP_02753 7.3e-164 fabK 1.3.1.9 S Nitronate monooxygenase
PHLHKCMP_02754 0.0 helD 3.6.4.12 L DNA helicase
PHLHKCMP_02755 7.2e-110 dedA S SNARE associated Golgi protein
PHLHKCMP_02756 1.3e-176 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
PHLHKCMP_02757 0.0 yjbQ P TrkA C-terminal domain protein
PHLHKCMP_02758 4e-124 pgm3 G Phosphoglycerate mutase family
PHLHKCMP_02759 3e-127 pgm3 G Phosphoglycerate mutase family
PHLHKCMP_02760 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PHLHKCMP_02761 2.7e-79 T Universal stress protein family
PHLHKCMP_02762 4.8e-99 padR K Virulence activator alpha C-term
PHLHKCMP_02763 1.7e-104 padC Q Phenolic acid decarboxylase
PHLHKCMP_02764 1.8e-139 tesE Q hydratase
PHLHKCMP_02765 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
PHLHKCMP_02766 3.6e-157 degV S DegV family
PHLHKCMP_02767 1.4e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
PHLHKCMP_02768 1.7e-254 pepC 3.4.22.40 E aminopeptidase
PHLHKCMP_02770 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PHLHKCMP_02771 1.8e-300
PHLHKCMP_02773 5.7e-157 S Bacterial protein of unknown function (DUF916)
PHLHKCMP_02774 2.6e-92 S Cell surface protein
PHLHKCMP_02775 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHLHKCMP_02776 5.2e-133 S Haloacid dehalogenase-like hydrolase
PHLHKCMP_02777 1.9e-144 rpsB J Belongs to the universal ribosomal protein uS2 family
PHLHKCMP_02778 1.8e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PHLHKCMP_02779 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PHLHKCMP_02780 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PHLHKCMP_02781 2.6e-146 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PHLHKCMP_02782 1.9e-136 cdsA 2.7.7.41 I Belongs to the CDS family
PHLHKCMP_02783 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PHLHKCMP_02784 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PHLHKCMP_02785 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHLHKCMP_02786 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
PHLHKCMP_02787 1.1e-217 nusA K Participates in both transcription termination and antitermination
PHLHKCMP_02788 9.5e-49 ylxR K Protein of unknown function (DUF448)
PHLHKCMP_02789 4.1e-47 ylxQ J ribosomal protein
PHLHKCMP_02790 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PHLHKCMP_02791 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PHLHKCMP_02792 4.3e-264 ydiN 5.4.99.5 G Major Facilitator
PHLHKCMP_02793 3.3e-214 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PHLHKCMP_02794 2.7e-91
PHLHKCMP_02795 1.4e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PHLHKCMP_02796 8e-194 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PHLHKCMP_02797 6.5e-85 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PHLHKCMP_02798 2.7e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PHLHKCMP_02799 2.3e-187 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PHLHKCMP_02800 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
PHLHKCMP_02801 9e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PHLHKCMP_02802 1.1e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PHLHKCMP_02803 0.0 dnaK O Heat shock 70 kDa protein
PHLHKCMP_02804 1.1e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PHLHKCMP_02805 7.4e-206 pbpX2 V Beta-lactamase
PHLHKCMP_02806 2.6e-18 dltX S D-Ala-teichoic acid biosynthesis protein
PHLHKCMP_02807 2.6e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHLHKCMP_02808 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
PHLHKCMP_02809 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHLHKCMP_02810 5.2e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PHLHKCMP_02811 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PHLHKCMP_02812 1.4e-49
PHLHKCMP_02813 1.4e-49
PHLHKCMP_02814 8.8e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PHLHKCMP_02815 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
PHLHKCMP_02816 6.4e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PHLHKCMP_02817 3.7e-57
PHLHKCMP_02818 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHLHKCMP_02819 2.5e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PHLHKCMP_02820 8.7e-113 3.1.3.18 J HAD-hyrolase-like
PHLHKCMP_02821 3.5e-165 yniA G Fructosamine kinase
PHLHKCMP_02822 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PHLHKCMP_02823 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
PHLHKCMP_02824 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PHLHKCMP_02825 1.9e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
PHLHKCMP_02826 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PHLHKCMP_02827 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_02828 1.7e-128 S Putative adhesin
PHLHKCMP_02829 1.9e-83 XK27_06920 S Protein of unknown function (DUF1700)
PHLHKCMP_02830 9.8e-52 K Transcriptional regulator
PHLHKCMP_02831 5.8e-79 KT response to antibiotic
PHLHKCMP_02832 4.5e-22 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PHLHKCMP_02833 3.9e-78 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PHLHKCMP_02834 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PHLHKCMP_02835 9e-122 tcyB E ABC transporter
PHLHKCMP_02836 4.4e-125 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PHLHKCMP_02837 1.4e-231 EK Aminotransferase, class I
PHLHKCMP_02838 6.1e-168 K LysR substrate binding domain
PHLHKCMP_02839 3.3e-167 ytbD EGP Major facilitator Superfamily
PHLHKCMP_02840 7e-94 M ErfK YbiS YcfS YnhG
PHLHKCMP_02841 9.6e-254 asnB 6.3.5.4 E Asparagine synthase
PHLHKCMP_02842 6.1e-23 asnB 6.3.5.4 E Asparagine synthase
PHLHKCMP_02843 6.7e-40 K LytTr DNA-binding domain
PHLHKCMP_02844 3.4e-83 K LytTr DNA-binding domain
PHLHKCMP_02845 6.3e-203 2.7.13.3 T GHKL domain
PHLHKCMP_02846 3.3e-98 fadR K Bacterial regulatory proteins, tetR family
PHLHKCMP_02847 3.6e-163 GM NmrA-like family
PHLHKCMP_02848 4.5e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PHLHKCMP_02849 0.0 M Glycosyl hydrolases family 25
PHLHKCMP_02850 4.7e-45 S Domain of unknown function (DUF1905)
PHLHKCMP_02851 8.6e-44 hxlR K HxlR-like helix-turn-helix
PHLHKCMP_02852 3.9e-99 S WxL domain surface cell wall-binding
PHLHKCMP_02853 9.5e-105 S WxL domain surface cell wall-binding
PHLHKCMP_02854 3e-163 S Cell surface protein
PHLHKCMP_02855 3.8e-143 XK27_00720 S Leucine-rich repeat (LRR) protein
PHLHKCMP_02856 2.6e-211 XK27_00720 S Leucine-rich repeat (LRR) protein
PHLHKCMP_02857 5.5e-261 nox C NADH oxidase
PHLHKCMP_02858 2.5e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PHLHKCMP_02859 0.0 pepO 3.4.24.71 O Peptidase family M13
PHLHKCMP_02860 2.1e-117 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
PHLHKCMP_02861 2.9e-31 copZ P Heavy-metal-associated domain
PHLHKCMP_02862 1.9e-95 dps P Belongs to the Dps family
PHLHKCMP_02863 5.1e-18
PHLHKCMP_02864 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
PHLHKCMP_02865 7.3e-55 txlA O Thioredoxin-like domain
PHLHKCMP_02866 3.1e-141 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PHLHKCMP_02867 1.8e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PHLHKCMP_02868 6.3e-160
PHLHKCMP_02869 5.2e-198 KLT Protein tyrosine kinase
PHLHKCMP_02870 9.2e-22 S Protein of unknown function (DUF4064)
PHLHKCMP_02871 9.6e-95 S Domain of unknown function (DUF4352)
PHLHKCMP_02872 3.4e-71 S Psort location Cytoplasmic, score
PHLHKCMP_02873 4.1e-54
PHLHKCMP_02875 5.2e-89 S membrane transporter protein
PHLHKCMP_02876 1.4e-54 azlD S branched-chain amino acid
PHLHKCMP_02877 4.5e-133 azlC E branched-chain amino acid
PHLHKCMP_02878 2e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
PHLHKCMP_02879 2.7e-236 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PHLHKCMP_02880 2.4e-212 hpk31 2.7.13.3 T Histidine kinase
PHLHKCMP_02881 1.6e-123 K response regulator
PHLHKCMP_02882 2.1e-106 yoaK S Protein of unknown function (DUF1275)
PHLHKCMP_02883 9e-153 psaA P Belongs to the bacterial solute-binding protein 9 family
PHLHKCMP_02884 1.8e-54 nudA S ASCH
PHLHKCMP_02885 2.3e-107 S SdpI/YhfL protein family
PHLHKCMP_02886 3.3e-94 M Lysin motif
PHLHKCMP_02887 1.6e-63 M LysM domain
PHLHKCMP_02888 1.5e-74 K helix_turn_helix, mercury resistance
PHLHKCMP_02889 2.2e-182 1.1.1.219 GM Male sterility protein
PHLHKCMP_02890 1.6e-279 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHLHKCMP_02891 4.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_02892 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PHLHKCMP_02893 2.6e-74 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHLHKCMP_02894 1.1e-147 dicA K Helix-turn-helix domain
PHLHKCMP_02895 1.6e-54
PHLHKCMP_02896 9.8e-160 T Calcineurin-like phosphoesterase superfamily domain
PHLHKCMP_02897 7.4e-64
PHLHKCMP_02898 5.1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PHLHKCMP_02899 3.5e-154 tagG U Transport permease protein
PHLHKCMP_02900 1.1e-217
PHLHKCMP_02901 5.1e-223 mtnE 2.6.1.83 E Aminotransferase
PHLHKCMP_02902 1.9e-146 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PHLHKCMP_02903 2e-86 metI U Binding-protein-dependent transport system inner membrane component
PHLHKCMP_02904 5.6e-125 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHLHKCMP_02905 3.3e-110 metQ P NLPA lipoprotein
PHLHKCMP_02906 3.4e-58 S CHY zinc finger
PHLHKCMP_02907 4.2e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PHLHKCMP_02908 6.8e-96 bioY S BioY family
PHLHKCMP_02909 3e-40
PHLHKCMP_02910 5.5e-280 pipD E Dipeptidase
PHLHKCMP_02911 8.8e-245 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PHLHKCMP_02912 4.5e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PHLHKCMP_02913 3.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PHLHKCMP_02914 3.8e-78 ywiB S Domain of unknown function (DUF1934)
PHLHKCMP_02915 1.8e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
PHLHKCMP_02916 5.8e-263 ywfO S HD domain protein
PHLHKCMP_02917 1.7e-148 yxeH S hydrolase
PHLHKCMP_02918 3.2e-125
PHLHKCMP_02919 9.1e-184 S DUF218 domain
PHLHKCMP_02920 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHLHKCMP_02921 1.8e-150 bla1 3.5.2.6 V Beta-lactamase enzyme family
PHLHKCMP_02922 1.6e-252 gshR 1.8.1.7 C Pyridine nucleotide-disulphide oxidoreductase
PHLHKCMP_02923 9.9e-180 proV E ABC transporter, ATP-binding protein
PHLHKCMP_02924 8.9e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PHLHKCMP_02925 1.5e-77 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
PHLHKCMP_02926 5.7e-67
PHLHKCMP_02927 3.4e-280
PHLHKCMP_02928 4.3e-161 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
PHLHKCMP_02929 4.2e-172 rihC 3.2.2.1 F Nucleoside
PHLHKCMP_02930 9.3e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PHLHKCMP_02931 9.3e-80
PHLHKCMP_02932 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
PHLHKCMP_02933 4.7e-232 flhF N Uncharacterized conserved protein (DUF2075)
PHLHKCMP_02934 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
PHLHKCMP_02935 7.9e-290 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHLHKCMP_02936 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_02937 1.8e-153 licT K CAT RNA binding domain
PHLHKCMP_02938 3.2e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHLHKCMP_02939 3.6e-290 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHLHKCMP_02940 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_02941 1.8e-156 licT K CAT RNA binding domain
PHLHKCMP_02942 5.8e-299 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
PHLHKCMP_02943 2.4e-38 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
PHLHKCMP_02944 3.4e-25
PHLHKCMP_02945 1.1e-49
PHLHKCMP_02946 2.7e-64 ycgX S Protein of unknown function (DUF1398)
PHLHKCMP_02947 1.3e-249 U Belongs to the purine-cytosine permease (2.A.39) family
PHLHKCMP_02949 2.5e-42 K LytTr DNA-binding domain
PHLHKCMP_02950 1.1e-30 S Protein of unknown function (DUF3021)
PHLHKCMP_02952 1.2e-19
PHLHKCMP_02953 2.8e-59
PHLHKCMP_02954 1.1e-59
PHLHKCMP_02956 2.7e-34
PHLHKCMP_02957 2.6e-280 S DNA primase
PHLHKCMP_02958 4.4e-122 L Primase C terminal 1 (PriCT-1)
PHLHKCMP_02959 6e-24
PHLHKCMP_02961 1.9e-41
PHLHKCMP_02962 3e-82 S Phage regulatory protein Rha (Phage_pRha)
PHLHKCMP_02965 1.3e-76 L Resolvase, N terminal domain
PHLHKCMP_02966 3.1e-123 O AAA domain (Cdc48 subfamily)
PHLHKCMP_02967 2.5e-247 O Subtilase family
PHLHKCMP_02968 2.1e-98 L 4.5 Transposon and IS
PHLHKCMP_02969 2.3e-30 L 4.5 Transposon and IS
PHLHKCMP_02970 4.2e-27 tnpR1 L Resolvase, N terminal domain
PHLHKCMP_02971 1.4e-35 XK27_05710 K Acetyltransferase (GNAT) domain
PHLHKCMP_02972 1.3e-07 ligA 6.5.1.2 L BRCA1 C Terminus (BRCT) domain
PHLHKCMP_02973 1.8e-146 U TraM recognition site of TraD and TraG
PHLHKCMP_02975 4.5e-105 L Psort location Cytoplasmic, score
PHLHKCMP_02976 2.2e-190 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PHLHKCMP_02977 1.7e-27
PHLHKCMP_02978 2.9e-13
PHLHKCMP_02980 2.8e-128 D Cellulose biosynthesis protein BcsQ
PHLHKCMP_02981 4.9e-26 I mechanosensitive ion channel activity
PHLHKCMP_02984 5.9e-19
PHLHKCMP_02985 7.7e-131 U type IV secretory pathway VirB4
PHLHKCMP_02987 1.4e-95 M CHAP domain
PHLHKCMP_02988 1.7e-15
PHLHKCMP_02990 6e-28 S Protein of unknown function (DUF3102)
PHLHKCMP_02999 1.7e-27 ruvB 3.6.4.12 L the current gene model (or a revised gene model) may contain a frame shift
PHLHKCMP_03000 1.3e-10 S metal-dependent membrane protease
PHLHKCMP_03003 8e-254 traI 5.99.1.2 L C-terminal repeat of topoisomerase
PHLHKCMP_03005 8.4e-41 L Protein of unknown function (DUF3991)
PHLHKCMP_03008 3.8e-124 clpB O Belongs to the ClpA ClpB family
PHLHKCMP_03011 1e-22 3.4.22.70 M Sortase family
PHLHKCMP_03012 4.1e-16 S by MetaGeneAnnotator
PHLHKCMP_03014 1.6e-25 D nuclear chromosome segregation
PHLHKCMP_03017 1e-14
PHLHKCMP_03019 5.1e-62 L Transposase and inactivated derivatives, IS30 family
PHLHKCMP_03020 9.8e-161 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHLHKCMP_03021 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PHLHKCMP_03022 1.5e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHLHKCMP_03023 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PHLHKCMP_03024 7.4e-64 yodB K Transcriptional regulator, HxlR family
PHLHKCMP_03025 4.2e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PHLHKCMP_03026 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHLHKCMP_03027 1.5e-185 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PHLHKCMP_03028 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
PHLHKCMP_03029 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHLHKCMP_03030 2.3e-96 liaI S membrane
PHLHKCMP_03031 1.2e-74 XK27_02470 K LytTr DNA-binding domain
PHLHKCMP_03032 7.3e-161 GK ROK family
PHLHKCMP_03033 1.2e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHLHKCMP_03034 2.8e-249 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_03035 2.6e-76 S Domain of unknown function (DUF3284)
PHLHKCMP_03036 3.9e-24
PHLHKCMP_03037 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHLHKCMP_03038 4.5e-129 K UbiC transcription regulator-associated domain protein
PHLHKCMP_03039 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PHLHKCMP_03040 7.2e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PHLHKCMP_03041 0.0 helD 3.6.4.12 L DNA helicase
PHLHKCMP_03042 2.8e-128 M Collagen binding domain
PHLHKCMP_03043 1.6e-99 tnp L DDE domain
PHLHKCMP_03044 1e-140 I transferase activity, transferring acyl groups other than amino-acyl groups
PHLHKCMP_03045 2.1e-104 K Transcriptional regulator, LysR family
PHLHKCMP_03046 4.4e-105 mdcH 2.3.1.39 I Acyl transferase domain
PHLHKCMP_03047 6.4e-280 mdcA 2.3.1.187 I Malonate decarboxylase, alpha subunit, transporter
PHLHKCMP_03048 9e-39 mdcC C Malonate decarboxylase delta subunit (MdcD)
PHLHKCMP_03049 1.3e-251 mdcD 4.1.1.87 I Malonate decarboxylase gamma subunit (MdcE)
PHLHKCMP_03050 3.7e-50 mdcG 2.7.7.66 H Phosphoribosyl-dephospho-CoA transferase MdcG
PHLHKCMP_03051 9e-67 yisY 1.11.1.10 S Alpha/beta hydrolase family
PHLHKCMP_03052 2.9e-79 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PHLHKCMP_03054 0.0 2.7.8.12 M glycerophosphotransferase
PHLHKCMP_03055 3.7e-229 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
PHLHKCMP_03056 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
PHLHKCMP_03057 1.3e-142
PHLHKCMP_03058 1.5e-306 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
PHLHKCMP_03060 1.5e-173 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PHLHKCMP_03061 5.9e-57
PHLHKCMP_03062 3.5e-56
PHLHKCMP_03063 3.6e-208 S Virulence-associated protein E
PHLHKCMP_03064 5.4e-120 L Primase C terminal 1 (PriCT-1)
PHLHKCMP_03066 6.7e-39
PHLHKCMP_03067 3.6e-67 S Phage regulatory protein Rha (Phage_pRha)
PHLHKCMP_03068 4.3e-71 K Phage regulatory protein
PHLHKCMP_03069 2.9e-11
PHLHKCMP_03071 2.8e-218 sip L Belongs to the 'phage' integrase family
PHLHKCMP_03072 1.3e-213 mdtG EGP Major facilitator Superfamily
PHLHKCMP_03073 2e-180 D Alpha beta
PHLHKCMP_03074 1.2e-77 M1-874 K Domain of unknown function (DUF1836)
PHLHKCMP_03075 1.4e-139 ugpE G ABC transporter permease
PHLHKCMP_03076 4.3e-258 ugpB G Bacterial extracellular solute-binding protein
PHLHKCMP_03077 1.3e-125 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PHLHKCMP_03078 1.4e-118 dck 2.7.1.74 F deoxynucleoside kinase
PHLHKCMP_03079 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PHLHKCMP_03080 9.3e-181 XK27_06930 V domain protein
PHLHKCMP_03082 1.8e-125 V Transport permease protein
PHLHKCMP_03083 1.1e-153 V ABC transporter
PHLHKCMP_03084 1.7e-174 K LytTr DNA-binding domain
PHLHKCMP_03086 0.0 kup P Transport of potassium into the cell
PHLHKCMP_03087 1.8e-151 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PHLHKCMP_03088 3.1e-179 K AI-2E family transporter
PHLHKCMP_03089 7.6e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
PHLHKCMP_03090 5.8e-59 qacC P Small Multidrug Resistance protein
PHLHKCMP_03091 4.3e-44 qacH U Small Multidrug Resistance protein
PHLHKCMP_03092 6.6e-116 hly S protein, hemolysin III
PHLHKCMP_03093 1.1e-53 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
PHLHKCMP_03094 1.4e-159 czcD P cation diffusion facilitator family transporter
PHLHKCMP_03095 1e-102 K Helix-turn-helix XRE-family like proteins
PHLHKCMP_03096 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PHLHKCMP_03097 1.8e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
PHLHKCMP_03098 1.4e-158 yunF F Protein of unknown function DUF72
PHLHKCMP_03099 1.2e-131 cobB K SIR2 family
PHLHKCMP_03100 1e-176
PHLHKCMP_03101 1.2e-228 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PHLHKCMP_03102 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PHLHKCMP_03103 1.3e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHLHKCMP_03104 4.1e-133 K Helix-turn-helix domain, rpiR family
PHLHKCMP_03105 3.1e-33 ykzG S Belongs to the UPF0356 family
PHLHKCMP_03106 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHLHKCMP_03107 2.8e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PHLHKCMP_03108 1.7e-28
PHLHKCMP_03109 5.9e-107 mltD CBM50 M NlpC P60 family protein
PHLHKCMP_03110 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHLHKCMP_03111 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PHLHKCMP_03112 1.8e-119 S Repeat protein
PHLHKCMP_03113 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PHLHKCMP_03114 1.8e-116 K Helix-turn-helix domain, rpiR family
PHLHKCMP_03115 1.1e-156 ccpB 5.1.1.1 K lacI family
PHLHKCMP_03116 5.7e-122 S Sucrose-6F-phosphate phosphohydrolase
PHLHKCMP_03117 9.2e-148 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHLHKCMP_03118 7e-178 iunH2 3.2.2.1 F nucleoside hydrolase
PHLHKCMP_03119 2.1e-97 drgA C Nitroreductase family
PHLHKCMP_03120 3.9e-167 S Polyphosphate kinase 2 (PPK2)
PHLHKCMP_03121 1.4e-177 3.6.4.13 S domain, Protein
PHLHKCMP_03122 3.4e-73 S Alpha/beta hydrolase of unknown function (DUF915)
PHLHKCMP_03123 3e-45 S Alpha/beta hydrolase of unknown function (DUF915)
PHLHKCMP_03124 5.2e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PHLHKCMP_03125 6.3e-114 N domain, Protein
PHLHKCMP_03126 2.6e-141 N domain, Protein
PHLHKCMP_03127 1.4e-192 S Bacterial protein of unknown function (DUF916)
PHLHKCMP_03128 2.6e-40 N WxL domain surface cell wall-binding
PHLHKCMP_03129 5e-67 N WxL domain surface cell wall-binding
PHLHKCMP_03130 2.6e-115 ktrA P domain protein
PHLHKCMP_03131 1.5e-239 ktrB P Potassium uptake protein
PHLHKCMP_03132 9.9e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PHLHKCMP_03133 9.2e-56 XK27_04120 S Putative amino acid metabolism
PHLHKCMP_03134 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
PHLHKCMP_03135 3.9e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PHLHKCMP_03136 4.6e-28
PHLHKCMP_03137 5.6e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PHLHKCMP_03138 5.9e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PHLHKCMP_03139 1.2e-17 S Protein of unknown function (DUF3021)
PHLHKCMP_03140 2.9e-36 K LytTr DNA-binding domain
PHLHKCMP_03141 1.4e-21 cylB V ABC-2 type transporter
PHLHKCMP_03142 1.9e-38 cylB U ABC-2 type transporter
PHLHKCMP_03143 2e-78 cylA V abc transporter atp-binding protein
PHLHKCMP_03144 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PHLHKCMP_03145 1.2e-86 divIVA D DivIVA domain protein
PHLHKCMP_03146 2.2e-145 ylmH S S4 domain protein
PHLHKCMP_03147 7.9e-36 yggT S YGGT family
PHLHKCMP_03148 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PHLHKCMP_03149 2.3e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PHLHKCMP_03150 3.5e-244 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PHLHKCMP_03151 2.2e-162 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PHLHKCMP_03152 5.9e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PHLHKCMP_03153 5.2e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PHLHKCMP_03154 7e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PHLHKCMP_03155 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PHLHKCMP_03156 3.7e-53 ftsL D Cell division protein FtsL
PHLHKCMP_03157 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PHLHKCMP_03158 1.9e-77 mraZ K Belongs to the MraZ family
PHLHKCMP_03159 4.2e-62 S Protein of unknown function (DUF3397)
PHLHKCMP_03160 1.2e-174 corA P CorA-like Mg2+ transporter protein
PHLHKCMP_03161 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PHLHKCMP_03162 3.4e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PHLHKCMP_03163 3.5e-112 ywnB S NAD(P)H-binding
PHLHKCMP_03164 1.3e-209 brnQ U Component of the transport system for branched-chain amino acids
PHLHKCMP_03166 5.3e-161 rrmA 2.1.1.187 H Methyltransferase
PHLHKCMP_03167 3e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PHLHKCMP_03168 1.2e-205 XK27_05220 S AI-2E family transporter
PHLHKCMP_03169 2.5e-56 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PHLHKCMP_03170 4.1e-192 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PHLHKCMP_03171 5.1e-116 cutC P Participates in the control of copper homeostasis
PHLHKCMP_03172 5.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PHLHKCMP_03173 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PHLHKCMP_03174 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
PHLHKCMP_03175 2e-112 yjbH Q Thioredoxin
PHLHKCMP_03176 0.0 pepF E oligoendopeptidase F
PHLHKCMP_03177 1.8e-206 coiA 3.6.4.12 S Competence protein
PHLHKCMP_03178 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PHLHKCMP_03179 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PHLHKCMP_03181 2.4e-176 bcr1 EGP Major facilitator Superfamily
PHLHKCMP_03183 1.5e-146 tatD L hydrolase, TatD family
PHLHKCMP_03184 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PHLHKCMP_03185 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PHLHKCMP_03186 3.2e-37 veg S Biofilm formation stimulator VEG
PHLHKCMP_03187 2.2e-162 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PHLHKCMP_03188 2.5e-180 S Prolyl oligopeptidase family
PHLHKCMP_03189 4.8e-128 fhuC 3.6.3.35 P ABC transporter
PHLHKCMP_03190 9.2e-131 znuB U ABC 3 transport family
PHLHKCMP_03192 3.4e-33
PHLHKCMP_03193 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PHLHKCMP_03194 1.5e-180 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
PHLHKCMP_03195 2.6e-126 ydcF S Gram-negative-bacterium-type cell wall biogenesis
PHLHKCMP_03196 1.4e-135 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PHLHKCMP_03197 4.5e-120 yfeX P Peroxidase
PHLHKCMP_03198 1.4e-14 yfeX P Peroxidase
PHLHKCMP_03199 6.1e-61 K transcriptional regulator
PHLHKCMP_03200 7.8e-10 4.1.1.46 S metal-dependent hydrolase of the TIM-barrel fold
PHLHKCMP_03201 8.2e-148 4.1.1.46 S Amidohydrolase
PHLHKCMP_03202 1.3e-53 S Uncharacterized protein conserved in bacteria (DUF2316)
PHLHKCMP_03203 5.1e-84
PHLHKCMP_03204 8.3e-111 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
PHLHKCMP_03205 7.8e-74 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
PHLHKCMP_03206 5.5e-127 K Helix-turn-helix domain, rpiR family
PHLHKCMP_03207 1.2e-157 S Alpha beta hydrolase
PHLHKCMP_03208 5.8e-112 GM NmrA-like family
PHLHKCMP_03209 4.1e-77 S Uncharacterized protein conserved in bacteria (DUF2255)
PHLHKCMP_03210 1.9e-161 K Transcriptional regulator
PHLHKCMP_03211 7.4e-172 C nadph quinone reductase
PHLHKCMP_03212 1.1e-13 S Alpha beta hydrolase
PHLHKCMP_03213 7.4e-269 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PHLHKCMP_03214 2.7e-103 desR K helix_turn_helix, Lux Regulon
PHLHKCMP_03215 2.2e-85 desK 2.7.13.3 T Histidine kinase
PHLHKCMP_03218 2e-31 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
PHLHKCMP_03219 2.2e-26
PHLHKCMP_03220 2.1e-27 ydeA S DJ-1/PfpI family
PHLHKCMP_03227 3.8e-30 rusA L Endodeoxyribonuclease RusA
PHLHKCMP_03229 2.1e-91
PHLHKCMP_03230 1.1e-108 tag 3.2.2.20 L Methyladenine glycosylase
PHLHKCMP_03231 9.4e-214 T diguanylate cyclase
PHLHKCMP_03232 2.6e-71 S Psort location Cytoplasmic, score
PHLHKCMP_03233 3.5e-280 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
PHLHKCMP_03234 5.6e-217 ykiI
PHLHKCMP_03235 0.0 V ABC transporter
PHLHKCMP_03236 1.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
PHLHKCMP_03237 1.3e-38
PHLHKCMP_03239 9.5e-248 EGP Major facilitator Superfamily
PHLHKCMP_03240 3.8e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
PHLHKCMP_03241 4.7e-83 cvpA S Colicin V production protein
PHLHKCMP_03242 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PHLHKCMP_03243 8.3e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PHLHKCMP_03244 9.8e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
PHLHKCMP_03245 1e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PHLHKCMP_03246 3e-99 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
PHLHKCMP_03247 2.9e-210 folP 2.5.1.15 H dihydropteroate synthase
PHLHKCMP_03248 1.5e-95 tag 3.2.2.20 L glycosylase
PHLHKCMP_03249 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PHLHKCMP_03250 2.5e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PHLHKCMP_03251 2.2e-123 jag S R3H domain protein
PHLHKCMP_03252 3.2e-195 Q Imidazolonepropionase and related amidohydrolases
PHLHKCMP_03253 4.2e-239 E ABC transporter, substratebinding protein
PHLHKCMP_03254 1.1e-27 E ABC transporter, substratebinding protein
PHLHKCMP_03255 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHLHKCMP_03256 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PHLHKCMP_03257 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PHLHKCMP_03258 5.6e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PHLHKCMP_03259 6.8e-34 S Threonine/Serine exporter, ThrE
PHLHKCMP_03260 2.7e-21 S Threonine/Serine exporter, ThrE
PHLHKCMP_03261 4.2e-59 thrE S Putative threonine/serine exporter
PHLHKCMP_03262 5.8e-22 thrE S Putative threonine/serine exporter
PHLHKCMP_03263 6e-31 cspC K Cold shock protein
PHLHKCMP_03264 1e-119 sirR K iron dependent repressor
PHLHKCMP_03265 2.2e-57
PHLHKCMP_03266 1.7e-84 merR K MerR HTH family regulatory protein
PHLHKCMP_03267 7e-270 lmrB EGP Major facilitator Superfamily
PHLHKCMP_03268 1.8e-117 S Domain of unknown function (DUF4811)
PHLHKCMP_03269 4.9e-95
PHLHKCMP_03270 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
PHLHKCMP_03271 2.2e-129 terC P membrane
PHLHKCMP_03272 1.9e-82 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PHLHKCMP_03273 2.3e-122 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PHLHKCMP_03274 1e-63 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PHLHKCMP_03275 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PHLHKCMP_03276 7.2e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PHLHKCMP_03277 2.4e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PHLHKCMP_03278 2.5e-98 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PHLHKCMP_03279 8.5e-108 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PHLHKCMP_03280 2.4e-77 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PHLHKCMP_03281 7.9e-18 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PHLHKCMP_03282 8.1e-73 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PHLHKCMP_03283 7.8e-135 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PHLHKCMP_03284 5.1e-84 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PHLHKCMP_03285 1e-12
PHLHKCMP_03288 5.9e-36 S YopX protein
PHLHKCMP_03295 1.4e-69 rusA L Endodeoxyribonuclease RusA
PHLHKCMP_03296 1.3e-61
PHLHKCMP_03297 5.1e-133 L Domain of unknown function (DUF4373)
PHLHKCMP_03298 8.6e-145 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
PHLHKCMP_03299 5.3e-135 recT L RecT family
PHLHKCMP_03300 1.4e-35
PHLHKCMP_03302 3.5e-97
PHLHKCMP_03306 5.5e-15 K Cro/C1-type HTH DNA-binding domain
PHLHKCMP_03307 9.6e-206 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
PHLHKCMP_03308 3.4e-186 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PHLHKCMP_03309 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
PHLHKCMP_03310 2.7e-163 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
PHLHKCMP_03311 3.1e-284 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
PHLHKCMP_03312 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PHLHKCMP_03313 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PHLHKCMP_03314 1.3e-153 ymdB S YmdB-like protein
PHLHKCMP_03315 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
PHLHKCMP_03316 5.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PHLHKCMP_03317 1.6e-230 cinA 3.5.1.42 S Belongs to the CinA family
PHLHKCMP_03318 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PHLHKCMP_03319 5.3e-108 ymfM S Helix-turn-helix domain
PHLHKCMP_03320 2.1e-249 ymfH S Peptidase M16
PHLHKCMP_03321 2.3e-229 ymfF S Peptidase M16 inactive domain protein
PHLHKCMP_03322 2.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
PHLHKCMP_03323 1.5e-155 aatB ET ABC transporter substrate-binding protein
PHLHKCMP_03324 3.7e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PHLHKCMP_03325 2.3e-108 glnP P ABC transporter permease
PHLHKCMP_03326 1.2e-146 minD D Belongs to the ParA family
PHLHKCMP_03327 1.8e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PHLHKCMP_03328 1.1e-87 mreD M rod shape-determining protein MreD
PHLHKCMP_03329 2.6e-144 mreC M Involved in formation and maintenance of cell shape
PHLHKCMP_03330 2.8e-161 mreB D cell shape determining protein MreB
PHLHKCMP_03331 1.2e-114 radC L DNA repair protein
PHLHKCMP_03332 5.2e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PHLHKCMP_03333 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PHLHKCMP_03334 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PHLHKCMP_03335 4.4e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PHLHKCMP_03336 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PHLHKCMP_03337 1.7e-218 iscS2 2.8.1.7 E Aminotransferase class V
PHLHKCMP_03338 3.6e-310 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PHLHKCMP_03339 1.9e-80 ytsP 1.8.4.14 T GAF domain-containing protein
PHLHKCMP_03340 1.2e-106 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PHLHKCMP_03341 5.2e-113 yktB S Belongs to the UPF0637 family
PHLHKCMP_03342 1.2e-79 yueI S Protein of unknown function (DUF1694)
PHLHKCMP_03343 1e-108 S Protein of unknown function (DUF1648)
PHLHKCMP_03344 5.6e-43 czrA K Helix-turn-helix domain
PHLHKCMP_03345 3.7e-230 malL 3.2.1.10 GH13 G COG0366 Glycosidases
PHLHKCMP_03346 9.2e-42 2.7.1.191 G PTS system fructose IIA component
PHLHKCMP_03347 3.5e-104 G PTS system mannose fructose sorbose family IID component
PHLHKCMP_03348 3.6e-103 G PTS system sorbose-specific iic component
PHLHKCMP_03349 3.9e-65 2.7.1.191 G PTS system sorbose subfamily IIB component
PHLHKCMP_03350 1.3e-94 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)