ORF_ID e_value Gene_name EC_number CAZy COGs Description
OKAIHIGN_00001 1.5e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OKAIHIGN_00002 7.7e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OKAIHIGN_00003 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OKAIHIGN_00004 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OKAIHIGN_00005 2.4e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OKAIHIGN_00006 4.2e-71 yabR J RNA binding
OKAIHIGN_00007 9.7e-44 divIC D Septum formation initiator
OKAIHIGN_00008 1.6e-39 yabO J S4 domain protein
OKAIHIGN_00009 7.7e-291 yabM S Polysaccharide biosynthesis protein
OKAIHIGN_00010 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OKAIHIGN_00011 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OKAIHIGN_00012 2.2e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OKAIHIGN_00013 3.5e-255 S Putative peptidoglycan binding domain
OKAIHIGN_00015 1.1e-113 S (CBS) domain
OKAIHIGN_00016 3.6e-61 ndoA L Toxic component of a toxin-antitoxin (TA) module
OKAIHIGN_00018 1.2e-213 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OKAIHIGN_00019 2.9e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OKAIHIGN_00020 1e-212 S nuclear-transcribed mRNA catabolic process, no-go decay
OKAIHIGN_00021 1.6e-240 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OKAIHIGN_00022 2.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OKAIHIGN_00023 1.9e-149
OKAIHIGN_00024 1.2e-144 htpX O Belongs to the peptidase M48B family
OKAIHIGN_00025 9.9e-95 lemA S LemA family
OKAIHIGN_00026 3.5e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OKAIHIGN_00027 9.7e-236 XK27_00720 S Leucine-rich repeat (LRR) protein
OKAIHIGN_00028 1.6e-110 XK27_00720 S regulation of response to stimulus
OKAIHIGN_00029 4.4e-109 S Cell surface protein
OKAIHIGN_00030 3.7e-32 S WxL domain surface cell wall-binding
OKAIHIGN_00031 1.7e-16 S WxL domain surface cell wall-binding
OKAIHIGN_00033 5.1e-92 XK27_00720 S regulation of response to stimulus
OKAIHIGN_00034 4e-12 S WxL domain surface cell wall-binding
OKAIHIGN_00035 1.8e-12 S WxL domain surface cell wall-binding
OKAIHIGN_00036 1.7e-17 S WxL domain surface cell wall-binding
OKAIHIGN_00037 8.7e-117 srtA 3.4.22.70 M sortase family
OKAIHIGN_00038 4.3e-42 rpmE2 J Ribosomal protein L31
OKAIHIGN_00039 1.1e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OKAIHIGN_00040 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
OKAIHIGN_00041 5.5e-127 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
OKAIHIGN_00042 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OKAIHIGN_00043 1.3e-72 K Transcriptional regulator
OKAIHIGN_00044 1.2e-233
OKAIHIGN_00045 1.6e-33 XK27_00720 S Leucine-rich repeat (LRR) protein
OKAIHIGN_00046 1.3e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OKAIHIGN_00047 5.8e-54 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OKAIHIGN_00048 4.9e-78 ywiB S Domain of unknown function (DUF1934)
OKAIHIGN_00049 3.2e-150 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
OKAIHIGN_00050 9.7e-266 ywfO S HD domain protein
OKAIHIGN_00051 4.8e-143 yxeH S hydrolase
OKAIHIGN_00052 0.0 xpkA 4.1.2.22, 4.1.2.9 G Phosphoketolase
OKAIHIGN_00053 7.5e-132 gntR K UbiC transcription regulator-associated domain protein
OKAIHIGN_00054 4.7e-70 racA K helix_turn_helix, mercury resistance
OKAIHIGN_00055 9.7e-56 S Domain of unknown function (DUF3899)
OKAIHIGN_00056 5.5e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OKAIHIGN_00057 2.9e-217 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OKAIHIGN_00058 1.5e-144 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OKAIHIGN_00061 1.1e-131 znuB U ABC 3 transport family
OKAIHIGN_00062 3e-130 fhuC P ABC transporter
OKAIHIGN_00063 1.6e-163 znuA P Belongs to the bacterial solute-binding protein 9 family
OKAIHIGN_00064 3.3e-154 S Prolyl oligopeptidase family
OKAIHIGN_00065 1.9e-85 KTV abc transporter atp-binding protein
OKAIHIGN_00066 1.6e-88 V ABC transporter
OKAIHIGN_00067 2.2e-54 V Transport permease protein
OKAIHIGN_00069 3.7e-90
OKAIHIGN_00070 2.9e-165 2.7.1.2 GK ROK family
OKAIHIGN_00071 1.2e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OKAIHIGN_00072 4.2e-209 xylR GK ROK family
OKAIHIGN_00073 1.8e-259 xylP G MFS/sugar transport protein
OKAIHIGN_00074 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
OKAIHIGN_00075 7.1e-109 ung2 3.2.2.27 L Uracil-DNA glycosylase
OKAIHIGN_00076 1.9e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OKAIHIGN_00077 4.3e-36 veg S Biofilm formation stimulator VEG
OKAIHIGN_00078 1.3e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OKAIHIGN_00079 4.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OKAIHIGN_00080 5.7e-146 tatD L hydrolase, TatD family
OKAIHIGN_00081 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OKAIHIGN_00082 1.1e-161 yunF F Protein of unknown function DUF72
OKAIHIGN_00083 3.8e-51
OKAIHIGN_00084 6.8e-130 cobB K SIR2 family
OKAIHIGN_00085 6e-177
OKAIHIGN_00086 7.2e-223 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
OKAIHIGN_00087 9.7e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
OKAIHIGN_00088 1.2e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
OKAIHIGN_00090 0.0 helD 3.6.4.12 L DNA helicase
OKAIHIGN_00091 1.4e-83
OKAIHIGN_00092 4.3e-55
OKAIHIGN_00093 5.2e-176 kdgR K helix_turn _helix lactose operon repressor
OKAIHIGN_00094 3.2e-87 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M sugar phosphate isomerase involved in capsule formation
OKAIHIGN_00095 7.2e-107 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase HUMPS family
OKAIHIGN_00096 1.2e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
OKAIHIGN_00097 1.4e-232 gntT EG Citrate transporter
OKAIHIGN_00098 4.2e-138 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
OKAIHIGN_00099 1.8e-35
OKAIHIGN_00100 6.4e-197 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OKAIHIGN_00102 9.1e-36 ygbF S Sugar efflux transporter for intercellular exchange
OKAIHIGN_00103 4.7e-249 gshR 1.8.1.7 C Glutathione reductase
OKAIHIGN_00104 4.1e-218 EGP Major facilitator Superfamily
OKAIHIGN_00105 1.5e-166 ropB K Helix-turn-helix XRE-family like proteins
OKAIHIGN_00106 1.3e-73 S Protein of unknown function (DUF3290)
OKAIHIGN_00107 8.1e-114 yviA S Protein of unknown function (DUF421)
OKAIHIGN_00108 2.4e-95 I NUDIX domain
OKAIHIGN_00110 5.5e-32 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
OKAIHIGN_00111 4e-23 ulaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
OKAIHIGN_00112 5.6e-189 ulaA 2.7.1.194 S PTS system sugar-specific permease component
OKAIHIGN_00113 3.1e-252 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OKAIHIGN_00114 5.2e-216 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OKAIHIGN_00115 4.8e-107 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
OKAIHIGN_00116 1.1e-53 S Protein of unknown function (DUF1516)
OKAIHIGN_00117 3.7e-96 1.5.1.3 H RibD C-terminal domain
OKAIHIGN_00118 3.2e-231 3.2.1.96, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OKAIHIGN_00119 1.1e-17
OKAIHIGN_00121 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OKAIHIGN_00122 4.7e-79 argR K Regulates arginine biosynthesis genes
OKAIHIGN_00123 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OKAIHIGN_00124 1.8e-51 yheA S Belongs to the UPF0342 family
OKAIHIGN_00125 3.7e-232 yhaO L Ser Thr phosphatase family protein
OKAIHIGN_00126 0.0 L AAA domain
OKAIHIGN_00127 6e-185 S Metal dependent phosphohydrolases with conserved 'HD' motif.
OKAIHIGN_00128 9.1e-151 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OKAIHIGN_00129 1.7e-48
OKAIHIGN_00130 1.5e-82 hit FG histidine triad
OKAIHIGN_00131 1.6e-134 ecsA V ABC transporter, ATP-binding protein
OKAIHIGN_00132 8e-219 ecsB U ABC transporter
OKAIHIGN_00133 1.9e-149 ytmP 2.7.1.89 M Choline/ethanolamine kinase
OKAIHIGN_00134 7.4e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OKAIHIGN_00135 3e-201 coiA 3.6.4.12 S Competence protein
OKAIHIGN_00136 0.0 pepF E oligoendopeptidase F
OKAIHIGN_00137 2.5e-158 degV S DegV family
OKAIHIGN_00138 5.8e-112 yjbH Q Thioredoxin
OKAIHIGN_00139 3.3e-118 yjbM 2.7.6.5 S RelA SpoT domain protein
OKAIHIGN_00140 1.5e-149 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OKAIHIGN_00141 2.9e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
OKAIHIGN_00142 1.5e-16 3.1.3.18 S Pfam Methyltransferase
OKAIHIGN_00143 1.7e-64 3.1.3.18 S Pfam Methyltransferase
OKAIHIGN_00144 3.9e-61 alr 5.1.1.1, 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OKAIHIGN_00145 4.9e-58 S Pfam Methyltransferase
OKAIHIGN_00146 7.8e-26
OKAIHIGN_00147 1e-268 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
OKAIHIGN_00148 2.1e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
OKAIHIGN_00149 6.5e-17 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
OKAIHIGN_00150 1.1e-107 cutC P Participates in the control of copper homeostasis
OKAIHIGN_00151 4.6e-203 XK27_05220 S AI-2E family transporter
OKAIHIGN_00152 9.4e-158 rrmA 2.1.1.187 H Methyltransferase
OKAIHIGN_00153 2.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OKAIHIGN_00154 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OKAIHIGN_00155 2.2e-12 S Protein of unknown function (DUF4044)
OKAIHIGN_00156 7.5e-61 S Protein of unknown function (DUF3397)
OKAIHIGN_00157 2e-79 mraZ K Belongs to the MraZ family
OKAIHIGN_00158 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OKAIHIGN_00159 3.2e-60 ftsL D Cell division protein FtsL
OKAIHIGN_00160 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OKAIHIGN_00161 1.9e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OKAIHIGN_00162 1.4e-248 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OKAIHIGN_00163 1.1e-198 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OKAIHIGN_00164 1.7e-146 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OKAIHIGN_00165 6e-244 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OKAIHIGN_00166 3.2e-215 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OKAIHIGN_00167 2.5e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OKAIHIGN_00168 4.1e-41 yggT S YGGT family
OKAIHIGN_00169 5.4e-144 ylmH S S4 domain protein
OKAIHIGN_00170 3.3e-92 divIVA D DivIVA domain protein
OKAIHIGN_00171 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OKAIHIGN_00172 2.2e-34 cspA K Cold shock protein
OKAIHIGN_00173 2.5e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
OKAIHIGN_00174 5.2e-31
OKAIHIGN_00175 2.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OKAIHIGN_00176 2.6e-222 iscS 2.8.1.7 E Aminotransferase class V
OKAIHIGN_00177 1.5e-58 XK27_04120 S Putative amino acid metabolism
OKAIHIGN_00178 3e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OKAIHIGN_00179 3.5e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
OKAIHIGN_00180 2.3e-119 S Repeat protein
OKAIHIGN_00181 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OKAIHIGN_00182 1.4e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OKAIHIGN_00183 1.2e-126 yoaK S Protein of unknown function (DUF1275)
OKAIHIGN_00184 2.5e-121 yecS E ABC transporter permease
OKAIHIGN_00185 1.3e-159 yckB ET Belongs to the bacterial solute-binding protein 3 family
OKAIHIGN_00186 1.1e-273 nylA 3.5.1.4 J Belongs to the amidase family
OKAIHIGN_00187 2.8e-307 E ABC transporter, substratebinding protein
OKAIHIGN_00188 5.5e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OKAIHIGN_00189 3.1e-189 yghZ C Aldo keto reductase family protein
OKAIHIGN_00190 1.4e-184 rbsR K helix_turn _helix lactose operon repressor
OKAIHIGN_00191 2.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OKAIHIGN_00192 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OKAIHIGN_00193 1.2e-168 ykfC 3.4.14.13 M NlpC/P60 family
OKAIHIGN_00194 8.8e-166 ypuA S Protein of unknown function (DUF1002)
OKAIHIGN_00195 6.3e-107 mltD CBM50 M NlpC P60 family protein
OKAIHIGN_00196 1.3e-28
OKAIHIGN_00197 5.3e-186 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
OKAIHIGN_00198 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OKAIHIGN_00199 1.2e-32 ykzG S Belongs to the UPF0356 family
OKAIHIGN_00200 3.1e-68
OKAIHIGN_00201 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OKAIHIGN_00202 7e-214 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
OKAIHIGN_00203 4.8e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
OKAIHIGN_00204 5.4e-205 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OKAIHIGN_00205 4.4e-269 lpdA 1.8.1.4 C Dehydrogenase
OKAIHIGN_00206 2.3e-162 1.1.1.27 C L-malate dehydrogenase activity
OKAIHIGN_00207 7.9e-45 yktA S Belongs to the UPF0223 family
OKAIHIGN_00208 6.7e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
OKAIHIGN_00209 0.0 typA T GTP-binding protein TypA
OKAIHIGN_00210 1.9e-209 ftsW D Belongs to the SEDS family
OKAIHIGN_00211 4.4e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
OKAIHIGN_00212 1.4e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
OKAIHIGN_00213 2.1e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OKAIHIGN_00214 2.4e-195 ylbL T Belongs to the peptidase S16 family
OKAIHIGN_00215 8.8e-106 comEA L Competence protein ComEA
OKAIHIGN_00216 1.2e-88 comEB 3.5.4.12 F ComE operon protein 2
OKAIHIGN_00217 0.0 comEC S Competence protein ComEC
OKAIHIGN_00218 7e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
OKAIHIGN_00219 1.2e-38 K transcriptional regulator
OKAIHIGN_00220 3.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OKAIHIGN_00221 5.5e-159 mntH P H( )-stimulated, divalent metal cation uptake system
OKAIHIGN_00222 4.2e-66 mntH P H( )-stimulated, divalent metal cation uptake system
OKAIHIGN_00223 1.7e-29
OKAIHIGN_00224 1.1e-57 K Winged helix DNA-binding domain
OKAIHIGN_00225 8.9e-251 S Uncharacterized protein conserved in bacteria (DUF2252)
OKAIHIGN_00226 4.9e-271 frvR K Mga helix-turn-helix domain
OKAIHIGN_00227 2.2e-35
OKAIHIGN_00228 3.7e-252 U Belongs to the purine-cytosine permease (2.A.39) family
OKAIHIGN_00229 4.9e-78 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
OKAIHIGN_00230 3.8e-84 S Bacterial PH domain
OKAIHIGN_00231 2.6e-256 ydbT S Bacterial PH domain
OKAIHIGN_00232 4e-194 yjcE P Sodium proton antiporter
OKAIHIGN_00233 2.1e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OKAIHIGN_00234 2e-212 EG GntP family permease
OKAIHIGN_00235 4.9e-193 KT Putative sugar diacid recognition
OKAIHIGN_00236 2.4e-175
OKAIHIGN_00237 1.7e-162 ytrB V ABC transporter, ATP-binding protein
OKAIHIGN_00238 2.1e-61 ytrA K helix_turn_helix gluconate operon transcriptional repressor
OKAIHIGN_00239 1.5e-124 S Protein of unknown function (DUF975)
OKAIHIGN_00240 1.3e-133 XK27_07210 6.1.1.6 S B3/4 domain
OKAIHIGN_00241 0.0 2.8.2.22 M Arylsulfotransferase Ig-like domain
OKAIHIGN_00242 1.4e-25
OKAIHIGN_00243 2.8e-179 xopQ 3.2.2.1, 3.2.2.8 F inosine-uridine preferring nucleoside hydrolase
OKAIHIGN_00244 7.8e-166 ydcZ S Putative inner membrane exporter, YdcZ
OKAIHIGN_00245 4.6e-96 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
OKAIHIGN_00246 8e-46 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
OKAIHIGN_00247 7.6e-259 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
OKAIHIGN_00248 5.7e-145 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
OKAIHIGN_00249 1.1e-30 citD C Covalent carrier of the coenzyme of citrate lyase
OKAIHIGN_00250 1.5e-111 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
OKAIHIGN_00251 5.7e-135 mleP S Membrane transport protein
OKAIHIGN_00252 3e-151 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
OKAIHIGN_00253 4e-109 citR K Putative sugar-binding domain
OKAIHIGN_00254 1.5e-82 ydjP I Alpha/beta hydrolase family
OKAIHIGN_00255 4.5e-311 ybiT S ABC transporter, ATP-binding protein
OKAIHIGN_00256 2.2e-159 K helix_turn_helix, arabinose operon control protein
OKAIHIGN_00257 1.9e-209 norA EGP Major facilitator Superfamily
OKAIHIGN_00258 2.7e-152 K LysR substrate binding domain
OKAIHIGN_00259 6e-159 MA20_14895 S Conserved hypothetical protein 698
OKAIHIGN_00260 9.7e-101 P Cadmium resistance transporter
OKAIHIGN_00261 2.1e-52 czrA K Transcriptional regulator, ArsR family
OKAIHIGN_00262 2.1e-311 mco Q Multicopper oxidase
OKAIHIGN_00263 5.6e-121 S SNARE associated Golgi protein
OKAIHIGN_00264 1e-310 cadA P P-type ATPase
OKAIHIGN_00265 2.2e-185 sdrF M Collagen binding domain
OKAIHIGN_00266 5e-69 S Iron-sulphur cluster biosynthesis
OKAIHIGN_00267 3.9e-60 gntR1 K Transcriptional regulator, GntR family
OKAIHIGN_00268 0.0 Q FtsX-like permease family
OKAIHIGN_00269 1.8e-136 cysA V ABC transporter, ATP-binding protein
OKAIHIGN_00270 7.2e-183 S Aldo keto reductase
OKAIHIGN_00271 5.7e-201 ytbD EGP Major facilitator Superfamily
OKAIHIGN_00272 6.3e-63 K Transcriptional regulator, HxlR family
OKAIHIGN_00273 1.5e-164
OKAIHIGN_00274 0.0 2.7.8.12 M glycerophosphotransferase
OKAIHIGN_00275 5.3e-72 K Transcriptional regulator
OKAIHIGN_00276 2.6e-152 1.6.5.2 GM NmrA-like family
OKAIHIGN_00277 1.2e-132 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKAIHIGN_00278 2.8e-151 3.2.1.37 GH43 K helix_turn_helix, arabinose operon control protein
OKAIHIGN_00279 0.0 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OKAIHIGN_00280 8.9e-226 G Major Facilitator
OKAIHIGN_00281 3.3e-124 IQ Enoyl-(Acyl carrier protein) reductase
OKAIHIGN_00282 1.2e-97 S membrane transporter protein
OKAIHIGN_00283 2e-286 E dipeptidase activity
OKAIHIGN_00284 8.1e-154 K acetyltransferase
OKAIHIGN_00285 2.2e-142 iap CBM50 M NlpC/P60 family
OKAIHIGN_00286 2.7e-73 spx4 1.20.4.1 P ArsC family
OKAIHIGN_00287 4.9e-249 yclG M Parallel beta-helix repeats
OKAIHIGN_00288 4.6e-64 K MarR family
OKAIHIGN_00289 2.8e-151 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OKAIHIGN_00290 5.7e-160 S Alpha/beta hydrolase of unknown function (DUF915)
OKAIHIGN_00291 1.4e-152 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
OKAIHIGN_00292 2.3e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OKAIHIGN_00293 5.4e-77
OKAIHIGN_00294 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
OKAIHIGN_00295 1.3e-254 malT G Major Facilitator
OKAIHIGN_00296 1.8e-181 malR K Transcriptional regulator, LacI family
OKAIHIGN_00297 7.9e-244 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
OKAIHIGN_00298 1.2e-123 K cheY-homologous receiver domain
OKAIHIGN_00299 0.0 S membrane
OKAIHIGN_00301 1.6e-168 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OKAIHIGN_00302 8.1e-28 S Protein of unknown function (DUF2929)
OKAIHIGN_00303 8.9e-95 2.7.6.5 S RelA SpoT domain protein
OKAIHIGN_00304 6.8e-226 mdtG EGP Major facilitator Superfamily
OKAIHIGN_00305 7.8e-140 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
OKAIHIGN_00306 2e-56 ywjH S Protein of unknown function (DUF1634)
OKAIHIGN_00307 2.9e-143 yxaA S membrane transporter protein
OKAIHIGN_00308 1e-156 lysR5 K LysR substrate binding domain
OKAIHIGN_00309 2.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
OKAIHIGN_00310 1.7e-246 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OKAIHIGN_00311 1.2e-162
OKAIHIGN_00312 3.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OKAIHIGN_00313 7.4e-163 I Carboxylesterase family
OKAIHIGN_00314 2.7e-149 M1-1017
OKAIHIGN_00315 5.4e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OKAIHIGN_00316 3.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OKAIHIGN_00317 1.3e-38 yrkD S Metal-sensitive transcriptional repressor
OKAIHIGN_00318 2.3e-56 trxA1 O Belongs to the thioredoxin family
OKAIHIGN_00319 2.2e-268 nox C NADH oxidase
OKAIHIGN_00320 1e-10 L Psort location Cytoplasmic, score
OKAIHIGN_00322 1e-48 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
OKAIHIGN_00323 1e-114
OKAIHIGN_00324 3.2e-135 K sugar-binding domain protein
OKAIHIGN_00325 4.8e-266 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
OKAIHIGN_00326 7.4e-178 S Domain of unknown function (DUF4432)
OKAIHIGN_00327 2.7e-239 fucP G Major Facilitator Superfamily
OKAIHIGN_00328 5.8e-35 yozE S Belongs to the UPF0346 family
OKAIHIGN_00329 6.5e-105 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
OKAIHIGN_00330 3e-162 ypmR E GDSL-like Lipase/Acylhydrolase
OKAIHIGN_00331 1.4e-148 DegV S EDD domain protein, DegV family
OKAIHIGN_00332 2.8e-114 hlyIII S protein, hemolysin III
OKAIHIGN_00333 3.3e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OKAIHIGN_00334 6.3e-187 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OKAIHIGN_00335 0.0 yfmR S ABC transporter, ATP-binding protein
OKAIHIGN_00336 8.3e-221 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OKAIHIGN_00337 1.3e-171 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OKAIHIGN_00338 1.2e-233 S Tetratricopeptide repeat protein
OKAIHIGN_00339 1.5e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OKAIHIGN_00340 7.4e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OKAIHIGN_00341 1.1e-210 rpsA 1.17.7.4 J Ribosomal protein S1
OKAIHIGN_00342 6.4e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OKAIHIGN_00343 8e-26 M Lysin motif
OKAIHIGN_00344 8.3e-252 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
OKAIHIGN_00345 4.3e-181 ypbB 5.1.3.1 S Helix-turn-helix domain
OKAIHIGN_00346 1.1e-93 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OKAIHIGN_00347 2.7e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OKAIHIGN_00348 3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OKAIHIGN_00349 2.4e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OKAIHIGN_00350 3.1e-71 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OKAIHIGN_00351 2.2e-165 xerD D recombinase XerD
OKAIHIGN_00352 6e-168 cvfB S S1 domain
OKAIHIGN_00353 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OKAIHIGN_00354 7.3e-127 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
OKAIHIGN_00355 0.0 dnaE 2.7.7.7 L DNA polymerase
OKAIHIGN_00356 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
OKAIHIGN_00357 2.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OKAIHIGN_00358 7.7e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OKAIHIGN_00359 6.6e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
OKAIHIGN_00360 0.0 ydgH S MMPL family
OKAIHIGN_00361 1.6e-88 K Transcriptional regulator
OKAIHIGN_00362 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OKAIHIGN_00363 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OKAIHIGN_00364 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OKAIHIGN_00365 1.5e-177 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OKAIHIGN_00366 9.5e-149 recO L Involved in DNA repair and RecF pathway recombination
OKAIHIGN_00367 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OKAIHIGN_00368 3.4e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OKAIHIGN_00369 8.5e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OKAIHIGN_00370 5.3e-181 phoH T phosphate starvation-inducible protein PhoH
OKAIHIGN_00371 7e-72 yqeY S YqeY-like protein
OKAIHIGN_00372 9.1e-65 hxlR K Transcriptional regulator, HxlR family
OKAIHIGN_00373 1.1e-189 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
OKAIHIGN_00374 1.3e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OKAIHIGN_00375 1.1e-150 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OKAIHIGN_00376 1.2e-171 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OKAIHIGN_00377 1.1e-241 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
OKAIHIGN_00378 8e-151 tagG U Transport permease protein
OKAIHIGN_00379 8.5e-189 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
OKAIHIGN_00380 3.8e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OKAIHIGN_00381 1.8e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OKAIHIGN_00382 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
OKAIHIGN_00383 1.5e-247 hisS 6.1.1.21 J histidyl-tRNA synthetase
OKAIHIGN_00384 2e-97
OKAIHIGN_00385 2.1e-157 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OKAIHIGN_00386 1.5e-163 yniA G Fructosamine kinase
OKAIHIGN_00387 8.1e-114 3.1.3.18 S HAD-hyrolase-like
OKAIHIGN_00388 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OKAIHIGN_00389 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OKAIHIGN_00390 1.8e-59
OKAIHIGN_00391 7e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OKAIHIGN_00392 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
OKAIHIGN_00393 1.2e-54
OKAIHIGN_00394 1.3e-26 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OKAIHIGN_00395 1.8e-62
OKAIHIGN_00397 3.3e-42
OKAIHIGN_00399 1.5e-19 asnB 6.3.5.4 E Protein of unknown function (DUF3923)
OKAIHIGN_00400 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OKAIHIGN_00401 3.2e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OKAIHIGN_00402 5.2e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKAIHIGN_00403 3.8e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
OKAIHIGN_00404 2.9e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OKAIHIGN_00405 1.7e-17 dltX S D-Ala-teichoic acid biosynthesis protein
OKAIHIGN_00406 4.9e-178 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OKAIHIGN_00407 0.0 dnaK O Heat shock 70 kDa protein
OKAIHIGN_00408 2.8e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OKAIHIGN_00409 7.8e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OKAIHIGN_00410 3.1e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OKAIHIGN_00411 6.9e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OKAIHIGN_00412 9.4e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OKAIHIGN_00413 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OKAIHIGN_00414 1.4e-44 ylxQ J ribosomal protein
OKAIHIGN_00415 2.3e-47 ylxR K Protein of unknown function (DUF448)
OKAIHIGN_00416 1.5e-190 nusA K Participates in both transcription termination and antitermination
OKAIHIGN_00417 1.8e-81 rimP J Required for maturation of 30S ribosomal subunits
OKAIHIGN_00418 1.4e-38
OKAIHIGN_00419 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OKAIHIGN_00420 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OKAIHIGN_00421 5.6e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
OKAIHIGN_00422 4.2e-136 cdsA 2.7.7.41 I Belongs to the CDS family
OKAIHIGN_00423 4e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OKAIHIGN_00424 3.2e-74
OKAIHIGN_00425 6.9e-85 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OKAIHIGN_00426 1.7e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OKAIHIGN_00427 1.9e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OKAIHIGN_00428 3.8e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
OKAIHIGN_00429 9.4e-135 S Haloacid dehalogenase-like hydrolase
OKAIHIGN_00430 1.5e-183 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKAIHIGN_00431 6.4e-44 yazA L GIY-YIG catalytic domain protein
OKAIHIGN_00432 3.3e-135 yabB 2.1.1.223 L Methyltransferase small domain
OKAIHIGN_00433 7.6e-120 plsC 2.3.1.51 I Acyltransferase
OKAIHIGN_00434 0.0 mdlB V ABC transporter
OKAIHIGN_00435 1.2e-287 mdlA V ABC transporter
OKAIHIGN_00436 1.6e-32 yneF S Uncharacterised protein family (UPF0154)
OKAIHIGN_00437 1.8e-37 ynzC S UPF0291 protein
OKAIHIGN_00438 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OKAIHIGN_00439 9.3e-77 F nucleoside 2-deoxyribosyltransferase
OKAIHIGN_00440 5.1e-78
OKAIHIGN_00441 8.7e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
OKAIHIGN_00442 2.4e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
OKAIHIGN_00443 1.2e-123 G phosphoglycerate mutase
OKAIHIGN_00444 7.7e-25 KT PspC domain
OKAIHIGN_00445 1e-81 ndk 2.7.4.6 F Belongs to the NDK family
OKAIHIGN_00449 1.7e-69 S MTH538 TIR-like domain (DUF1863)
OKAIHIGN_00450 4.5e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
OKAIHIGN_00451 5.4e-34
OKAIHIGN_00453 1.1e-77 T Universal stress protein family
OKAIHIGN_00454 1.6e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OKAIHIGN_00455 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OKAIHIGN_00456 1.5e-54 yrvD S Pfam:DUF1049
OKAIHIGN_00457 5.7e-180 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OKAIHIGN_00458 5e-28
OKAIHIGN_00459 6.2e-105
OKAIHIGN_00460 1.3e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OKAIHIGN_00461 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OKAIHIGN_00462 1.1e-15
OKAIHIGN_00463 3.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
OKAIHIGN_00464 6.6e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
OKAIHIGN_00465 6.9e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OKAIHIGN_00466 8.3e-222 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OKAIHIGN_00467 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OKAIHIGN_00468 3.1e-162 S Tetratricopeptide repeat
OKAIHIGN_00469 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OKAIHIGN_00470 1.3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OKAIHIGN_00471 2.1e-33 rpsT J Binds directly to 16S ribosomal RNA
OKAIHIGN_00472 5.4e-45
OKAIHIGN_00473 5.4e-24
OKAIHIGN_00474 7.8e-120 yliE T Putative diguanylate phosphodiesterase
OKAIHIGN_00475 1.6e-197 ybiR P Citrate transporter
OKAIHIGN_00476 9.9e-164 S NAD:arginine ADP-ribosyltransferase
OKAIHIGN_00477 8.2e-117
OKAIHIGN_00478 1e-85 gepA S Protein of unknown function (DUF4065)
OKAIHIGN_00479 1.3e-42
OKAIHIGN_00480 1.6e-31 S Phage gp6-like head-tail connector protein
OKAIHIGN_00481 4e-207 S Caudovirus prohead serine protease
OKAIHIGN_00482 5.4e-190 S Phage portal protein
OKAIHIGN_00484 4.7e-310 terL S overlaps another CDS with the same product name
OKAIHIGN_00485 1.4e-75 terS L overlaps another CDS with the same product name
OKAIHIGN_00486 2.8e-51 L HNH endonuclease
OKAIHIGN_00487 2.2e-17 S head-tail joining protein
OKAIHIGN_00489 8.3e-59
OKAIHIGN_00490 3.7e-244 S Virulence-associated protein E
OKAIHIGN_00491 1.1e-102 L Bifunctional DNA primase/polymerase, N-terminal
OKAIHIGN_00492 3.1e-07
OKAIHIGN_00495 4.3e-206 sip L Belongs to the 'phage' integrase family
OKAIHIGN_00498 2.4e-76 S Protein of unknown function (DUF1211)
OKAIHIGN_00499 5.2e-81 tspO T TspO/MBR family
OKAIHIGN_00500 0.0 S Bacterial membrane protein YfhO
OKAIHIGN_00501 7.1e-261 pgi 5.3.1.9 G Belongs to the GPI family
OKAIHIGN_00502 6.4e-154 glcU U sugar transport
OKAIHIGN_00503 4.9e-210 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
OKAIHIGN_00504 5.5e-267 T PhoQ Sensor
OKAIHIGN_00505 9e-147 K response regulator
OKAIHIGN_00508 0.0 rafA 3.2.1.22 G Melibiase
OKAIHIGN_00509 6.6e-120 K AraC family transcriptional regulator
OKAIHIGN_00510 3.8e-209 G MFS/sugar transport protein
OKAIHIGN_00511 1.9e-253 dapE 3.5.1.18 E Peptidase dimerisation domain
OKAIHIGN_00512 1.7e-72 S Sigma factor regulator C-terminal
OKAIHIGN_00513 3.5e-45 sigM K Sigma-70 region 2
OKAIHIGN_00514 1.2e-255 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OKAIHIGN_00515 2.9e-87
OKAIHIGN_00516 3.2e-54 ypaA S Protein of unknown function (DUF1304)
OKAIHIGN_00518 8.3e-24
OKAIHIGN_00519 1.3e-78 O OsmC-like protein
OKAIHIGN_00520 1.9e-25
OKAIHIGN_00521 2.3e-75 K Transcriptional regulator
OKAIHIGN_00522 1.7e-75 S Domain of unknown function (DUF5067)
OKAIHIGN_00523 5.3e-150 licD M LicD family
OKAIHIGN_00524 7e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
OKAIHIGN_00525 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OKAIHIGN_00526 5.8e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
OKAIHIGN_00527 6.2e-137 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
OKAIHIGN_00528 2.9e-171 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OKAIHIGN_00529 9.5e-161 isdE P Periplasmic binding protein
OKAIHIGN_00530 2.2e-89 M Iron Transport-associated domain
OKAIHIGN_00531 1e-162 M Iron Transport-associated domain
OKAIHIGN_00533 9e-11 S transferase activity, transferring acyl groups
OKAIHIGN_00535 1e-193 M Glycosyl hydrolases family 25
OKAIHIGN_00538 2.7e-29
OKAIHIGN_00540 3.1e-32
OKAIHIGN_00542 2e-37
OKAIHIGN_00543 3.6e-72
OKAIHIGN_00544 4.9e-181 S Baseplate J-like protein
OKAIHIGN_00545 3.6e-11 S Protein of unknown function (DUF2634)
OKAIHIGN_00546 1e-54
OKAIHIGN_00547 4e-210
OKAIHIGN_00548 8.6e-66
OKAIHIGN_00549 1.8e-108 S N-acetylmuramoyl-L-alanine amidase activity
OKAIHIGN_00550 4e-185 M Phage tail tape measure protein TP901
OKAIHIGN_00552 1.7e-63
OKAIHIGN_00553 3.6e-67
OKAIHIGN_00554 1.3e-140 S Protein of unknown function (DUF3383)
OKAIHIGN_00555 2.1e-58
OKAIHIGN_00556 1.1e-62
OKAIHIGN_00557 3.2e-96
OKAIHIGN_00558 3.8e-51 S Protein of unknown function (DUF4054)
OKAIHIGN_00559 8e-58
OKAIHIGN_00560 1e-159 S Uncharacterized protein conserved in bacteria (DUF2184)
OKAIHIGN_00561 2.9e-76
OKAIHIGN_00562 2.1e-157 S Uncharacterized protein conserved in bacteria (DUF2213)
OKAIHIGN_00564 1.3e-127 S Phage Mu protein F like protein
OKAIHIGN_00565 1.3e-257 S Protein of unknown function (DUF1073)
OKAIHIGN_00566 4.3e-165 S Phage terminase large subunit
OKAIHIGN_00568 9.3e-109 S DNA packaging
OKAIHIGN_00574 3.6e-28 uspA T Universal stress protein family
OKAIHIGN_00576 2.9e-44 arpU S Phage transcriptional regulator, ArpU family
OKAIHIGN_00581 9.3e-42 S Endodeoxyribonuclease RusA
OKAIHIGN_00582 3.8e-56 K AntA/AntB antirepressor
OKAIHIGN_00583 6.9e-37 L Domain of unknown function (DUF4373)
OKAIHIGN_00584 3.3e-79 recT L RecT family
OKAIHIGN_00585 5.8e-94 yqaJ L YqaJ-like viral recombinase domain
OKAIHIGN_00590 1.6e-35
OKAIHIGN_00595 6.5e-26 K Helix-turn-helix
OKAIHIGN_00596 4.6e-70 S Pfam:Peptidase_M78
OKAIHIGN_00597 4.5e-24 S Domain of unknown function (DUF4145)
OKAIHIGN_00599 3.6e-17
OKAIHIGN_00601 2.4e-38
OKAIHIGN_00602 1.6e-40 S Protein of unknown function (DUF3037)
OKAIHIGN_00603 2.3e-141 S Pfam:Arm-DNA-bind_4
OKAIHIGN_00608 4.1e-69 L Integrase core domain
OKAIHIGN_00609 1.9e-15 L Belongs to the 'phage' integrase family
OKAIHIGN_00611 1.1e-17
OKAIHIGN_00612 9.7e-94 S T5orf172
OKAIHIGN_00613 1.3e-34 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OKAIHIGN_00615 1.4e-48 KLT serine threonine protein kinase
OKAIHIGN_00616 5.7e-32
OKAIHIGN_00617 1.4e-23
OKAIHIGN_00619 4.7e-09 ps115 K Transcriptional regulator
OKAIHIGN_00622 8.2e-15
OKAIHIGN_00623 2.6e-87 S Phage regulatory protein
OKAIHIGN_00625 9.6e-33
OKAIHIGN_00627 2.8e-26
OKAIHIGN_00630 2.1e-10 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OKAIHIGN_00635 4.1e-49 S Siphovirus Gp157
OKAIHIGN_00636 4.9e-24 S ERF superfamily
OKAIHIGN_00637 2.4e-53 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OKAIHIGN_00638 4e-85 S Putative HNHc nuclease
OKAIHIGN_00640 4.1e-60 L DnaD domain protein
OKAIHIGN_00645 6.5e-26 S YopX protein
OKAIHIGN_00646 1.9e-24
OKAIHIGN_00649 1.3e-46 S Transcriptional regulator, RinA family
OKAIHIGN_00650 3.1e-53 xtmA S Putative ATPase subunit of terminase (gpP-like)
OKAIHIGN_00651 4e-211 S Terminase RNAseH like domain
OKAIHIGN_00652 5.3e-121 S Phage portal protein, SPP1 Gp6-like
OKAIHIGN_00654 1.6e-102 S Phage Mu protein F like protein
OKAIHIGN_00656 3.2e-12 S Domain of unknown function (DUF4355)
OKAIHIGN_00657 1.3e-29
OKAIHIGN_00658 3e-113 S Phage major capsid protein E
OKAIHIGN_00659 7.1e-18
OKAIHIGN_00660 3.3e-21
OKAIHIGN_00661 6.7e-56
OKAIHIGN_00662 2.8e-21
OKAIHIGN_00663 5.4e-39
OKAIHIGN_00664 5e-32
OKAIHIGN_00665 2.2e-14
OKAIHIGN_00666 3.4e-168 D NLP P60 protein
OKAIHIGN_00667 5.9e-32
OKAIHIGN_00668 1.6e-93 sidC GT2,GT4 LM DNA recombination
OKAIHIGN_00669 1.1e-10 S Protein of unknown function (DUF1617)
OKAIHIGN_00670 2e-22
OKAIHIGN_00671 1.9e-19
OKAIHIGN_00673 2.5e-42
OKAIHIGN_00674 1.4e-86 3.2.1.17 M hydrolase, family 25
OKAIHIGN_00675 1.7e-25 S Haemolysin XhlA
OKAIHIGN_00677 0.0 uvrA3 L ABC transporter
OKAIHIGN_00680 5.7e-15 M lysozyme activity
OKAIHIGN_00681 1.7e-95 soj D CobQ CobB MinD ParA nucleotide binding domain protein
OKAIHIGN_00682 1.4e-17
OKAIHIGN_00684 2.1e-82 3.2.1.17 M hydrolase, family 25
OKAIHIGN_00685 2.1e-41
OKAIHIGN_00686 1.7e-49 D nuclear chromosome segregation
OKAIHIGN_00688 1.8e-181 Z012_12235 S Baseplate J-like protein
OKAIHIGN_00690 8.3e-43
OKAIHIGN_00691 8.7e-133
OKAIHIGN_00692 1.6e-15
OKAIHIGN_00693 5.6e-60 M LysM domain
OKAIHIGN_00694 3.4e-146 M Membrane
OKAIHIGN_00698 9.2e-09 Z012_02110 S Protein of unknown function (DUF3383)
OKAIHIGN_00702 1.8e-59
OKAIHIGN_00704 6.5e-177 gpG
OKAIHIGN_00705 6.8e-44 S Domain of unknown function (DUF4355)
OKAIHIGN_00706 2.2e-75 S Phage Mu protein F like protein
OKAIHIGN_00707 4.5e-263 S Phage portal protein, SPP1 Gp6-like
OKAIHIGN_00709 1.8e-160 ps334 S Terminase-like family
OKAIHIGN_00710 5.9e-71 L Terminase small subunit
OKAIHIGN_00712 5e-25 S Protein of unknown function (DUF2829)
OKAIHIGN_00714 2.9e-35 S Transcriptional regulator, RinA family
OKAIHIGN_00716 5.2e-30
OKAIHIGN_00718 4e-26 S YopX protein
OKAIHIGN_00720 1.1e-72 pi346 L IstB-like ATP binding protein
OKAIHIGN_00721 5e-40 L Helix-turn-helix domain
OKAIHIGN_00723 2.2e-96 S Putative HNHc nuclease
OKAIHIGN_00725 1.4e-09
OKAIHIGN_00729 4.5e-27 S Uncharacterized protein conserved in bacteria (DUF2188)
OKAIHIGN_00731 7.3e-37 K BRO family, N-terminal domain
OKAIHIGN_00735 6e-33 XK27_10050 K Peptidase S24-like
OKAIHIGN_00736 1.9e-15 S Protein of unknown function (DUF805)
OKAIHIGN_00739 1.6e-33
OKAIHIGN_00740 1.6e-118 L Probable transposase
OKAIHIGN_00742 2.7e-45 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
OKAIHIGN_00744 1.6e-55
OKAIHIGN_00748 8.4e-19 L PFAM Integrase catalytic region
OKAIHIGN_00749 2.9e-42
OKAIHIGN_00750 1e-55 L Integrase core domain
OKAIHIGN_00751 9e-35 L Transposase and inactivated derivatives, IS30 family
OKAIHIGN_00752 2.3e-13 L recombinase activity
OKAIHIGN_00754 3.9e-52 L Domain of unknown function (DUF927)
OKAIHIGN_00760 7.6e-20 3.1.3.16 V Protein of unknown function (DUF1643)
OKAIHIGN_00762 1.1e-10 S Mor transcription activator family
OKAIHIGN_00765 5e-22 S Mor transcription activator family
OKAIHIGN_00767 1.6e-32 S Abortive infection C-terminus
OKAIHIGN_00768 2.1e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OKAIHIGN_00769 3.4e-194 htrA 3.4.21.107 O serine protease
OKAIHIGN_00770 3.4e-157 vicX 3.1.26.11 S domain protein
OKAIHIGN_00771 6.1e-149 yycI S YycH protein
OKAIHIGN_00772 4.8e-238 yycH S YycH protein
OKAIHIGN_00773 0.0 vicK 2.7.13.3 T Histidine kinase
OKAIHIGN_00774 5.7e-132 K response regulator
OKAIHIGN_00776 2.4e-112 E Matrixin
OKAIHIGN_00777 1.7e-35
OKAIHIGN_00778 1.2e-302 E ABC transporter, substratebinding protein
OKAIHIGN_00779 2.9e-20
OKAIHIGN_00780 2.9e-210 yttB EGP Major facilitator Superfamily
OKAIHIGN_00781 3.8e-101 S NADPH-dependent FMN reductase
OKAIHIGN_00782 6.6e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OKAIHIGN_00785 7.2e-64 rplI J Binds to the 23S rRNA
OKAIHIGN_00786 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OKAIHIGN_00787 7e-74 S membrane transporter protein
OKAIHIGN_00796 1.2e-07
OKAIHIGN_00806 8e-232 N Uncharacterized conserved protein (DUF2075)
OKAIHIGN_00807 2.6e-91 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
OKAIHIGN_00808 4.2e-138 yhfI S Metallo-beta-lactamase superfamily
OKAIHIGN_00809 1e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OKAIHIGN_00810 1.7e-120 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
OKAIHIGN_00811 5.1e-105 T EAL domain
OKAIHIGN_00812 2.6e-91
OKAIHIGN_00813 2.3e-248 pgaC GT2 M Glycosyl transferase
OKAIHIGN_00815 3.1e-101 ytqB J Putative rRNA methylase
OKAIHIGN_00816 3e-116 pgpB1 3.6.1.27 I Acid phosphatase homologues
OKAIHIGN_00817 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OKAIHIGN_00818 1e-46
OKAIHIGN_00819 2.7e-120 P ABC-type multidrug transport system ATPase component
OKAIHIGN_00820 4.8e-145 S NADPH-dependent FMN reductase
OKAIHIGN_00821 4.4e-52
OKAIHIGN_00822 1.5e-297 ytgP S Polysaccharide biosynthesis protein
OKAIHIGN_00823 1.4e-124 rluB 5.4.99.19, 5.4.99.20, 5.4.99.21, 5.4.99.22 J pseudouridine synthase activity
OKAIHIGN_00824 6.6e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OKAIHIGN_00825 1.5e-269 pepV 3.5.1.18 E dipeptidase PepV
OKAIHIGN_00826 8.2e-85 uspA T Belongs to the universal stress protein A family
OKAIHIGN_00827 2.6e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
OKAIHIGN_00828 3.2e-245 cycA E Amino acid permease
OKAIHIGN_00829 2e-55 ytzB S Small secreted protein
OKAIHIGN_00830 4e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OKAIHIGN_00831 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OKAIHIGN_00832 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OKAIHIGN_00833 4.3e-258 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OKAIHIGN_00834 6.2e-134 pnuC H nicotinamide mononucleotide transporter
OKAIHIGN_00835 2.1e-118 ybhL S Belongs to the BI1 family
OKAIHIGN_00836 3e-235 F Permease
OKAIHIGN_00837 2.7e-260 guaD 3.5.4.3 F Amidohydrolase family
OKAIHIGN_00838 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OKAIHIGN_00839 1.3e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OKAIHIGN_00840 1.8e-110 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OKAIHIGN_00841 7.8e-88 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OKAIHIGN_00842 1.9e-245 dnaB L replication initiation and membrane attachment
OKAIHIGN_00843 1.9e-164 dnaI L Primosomal protein DnaI
OKAIHIGN_00844 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OKAIHIGN_00845 4.4e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OKAIHIGN_00846 7.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OKAIHIGN_00847 3.7e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OKAIHIGN_00848 1.3e-36 S regulation of response to stimulus
OKAIHIGN_00849 2.9e-65 M domain protein
OKAIHIGN_00850 3.2e-103 yqeG S HAD phosphatase, family IIIA
OKAIHIGN_00851 1.9e-222 yqeH S Ribosome biogenesis GTPase YqeH
OKAIHIGN_00852 1.3e-48 yhbY J RNA-binding protein
OKAIHIGN_00853 5.9e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OKAIHIGN_00854 4e-107 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
OKAIHIGN_00855 1.6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OKAIHIGN_00856 1.1e-138 yqeM Q Methyltransferase
OKAIHIGN_00857 1e-215 ylbM S Belongs to the UPF0348 family
OKAIHIGN_00858 8.6e-96 yceD S Uncharacterized ACR, COG1399
OKAIHIGN_00859 6.9e-29 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OKAIHIGN_00860 4.6e-146 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
OKAIHIGN_00861 8.2e-51 K Transcriptional regulator, ArsR family
OKAIHIGN_00862 4.4e-115 zmp3 O Zinc-dependent metalloprotease
OKAIHIGN_00863 1.9e-194 adhP 1.1.1.1 C alcohol dehydrogenase
OKAIHIGN_00864 2.8e-120 K response regulator
OKAIHIGN_00865 9.3e-292 arlS 2.7.13.3 T Histidine kinase
OKAIHIGN_00866 1.7e-69 S Protein of unknown function (DUF1093)
OKAIHIGN_00867 1.5e-134 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OKAIHIGN_00868 2.7e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OKAIHIGN_00869 6.1e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OKAIHIGN_00870 2e-91 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
OKAIHIGN_00871 1.1e-67 yodB K Transcriptional regulator, HxlR family
OKAIHIGN_00872 3.8e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OKAIHIGN_00873 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OKAIHIGN_00874 3.8e-207 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OKAIHIGN_00875 1e-119 udk 2.7.1.48 F Cytidine monophosphokinase
OKAIHIGN_00876 6.3e-71 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OKAIHIGN_00877 1.7e-56 yneR S Belongs to the HesB IscA family
OKAIHIGN_00878 0.0 S membrane
OKAIHIGN_00879 6.5e-28 CP_0775 S Domain of unknown function (DUF378)
OKAIHIGN_00880 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
OKAIHIGN_00881 2.5e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OKAIHIGN_00882 8.3e-91 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OKAIHIGN_00883 9.9e-118 gluP 3.4.21.105 S Peptidase, S54 family
OKAIHIGN_00884 9.3e-36 yqgQ S Bacterial protein of unknown function (DUF910)
OKAIHIGN_00885 1.2e-180 glk 2.7.1.2 G Glucokinase
OKAIHIGN_00886 2.1e-70 yqhL P Rhodanese-like protein
OKAIHIGN_00887 3.1e-23 WQ51_02665 S Protein of unknown function (DUF3042)
OKAIHIGN_00888 1.6e-140 glpQ 3.1.4.46 C phosphodiesterase
OKAIHIGN_00889 1.7e-168 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OKAIHIGN_00890 2.1e-64 glnR K Transcriptional regulator
OKAIHIGN_00891 4.9e-262 glnA 6.3.1.2 E glutamine synthetase
OKAIHIGN_00892 1.1e-156
OKAIHIGN_00893 1.8e-178
OKAIHIGN_00894 1.2e-94 dut S Protein conserved in bacteria
OKAIHIGN_00895 2e-94 K Transcriptional regulator
OKAIHIGN_00896 3.4e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
OKAIHIGN_00897 2.2e-57 ysxB J Cysteine protease Prp
OKAIHIGN_00898 1.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OKAIHIGN_00899 2e-189 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
OKAIHIGN_00900 1.3e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OKAIHIGN_00901 4.8e-73 yqhY S Asp23 family, cell envelope-related function
OKAIHIGN_00902 7.2e-74 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OKAIHIGN_00903 1.2e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OKAIHIGN_00904 1e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OKAIHIGN_00905 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OKAIHIGN_00906 1.6e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OKAIHIGN_00907 2.6e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
OKAIHIGN_00908 3.7e-76 argR K Regulates arginine biosynthesis genes
OKAIHIGN_00909 8.8e-309 recN L May be involved in recombinational repair of damaged DNA
OKAIHIGN_00910 3.6e-64 M domain protein
OKAIHIGN_00912 1.1e-50
OKAIHIGN_00913 3.3e-104 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OKAIHIGN_00914 4.9e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OKAIHIGN_00915 6.3e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OKAIHIGN_00916 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OKAIHIGN_00917 2.4e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OKAIHIGN_00918 4.6e-228 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OKAIHIGN_00919 1.5e-130 stp 3.1.3.16 T phosphatase
OKAIHIGN_00920 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OKAIHIGN_00921 1.4e-167 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OKAIHIGN_00922 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OKAIHIGN_00923 4.4e-126 thiN 2.7.6.2 H thiamine pyrophosphokinase
OKAIHIGN_00924 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OKAIHIGN_00925 5.2e-57 asp S Asp23 family, cell envelope-related function
OKAIHIGN_00926 4.7e-311 yloV S DAK2 domain fusion protein YloV
OKAIHIGN_00927 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OKAIHIGN_00928 1.4e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OKAIHIGN_00929 6.4e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OKAIHIGN_00930 2.8e-128 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OKAIHIGN_00931 0.0 smc D Required for chromosome condensation and partitioning
OKAIHIGN_00932 4.6e-173 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OKAIHIGN_00933 2.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OKAIHIGN_00934 8.3e-207 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OKAIHIGN_00935 0.0 pacL 3.6.3.8 P P-type ATPase
OKAIHIGN_00936 1.4e-212 3.1.3.1 S associated with various cellular activities
OKAIHIGN_00937 1.3e-230 S Putative metallopeptidase domain
OKAIHIGN_00938 6.1e-48
OKAIHIGN_00939 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OKAIHIGN_00940 1.9e-40 ylqC S Belongs to the UPF0109 family
OKAIHIGN_00941 1.6e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OKAIHIGN_00942 4.5e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OKAIHIGN_00943 2.7e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OKAIHIGN_00944 1.7e-189 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OKAIHIGN_00945 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OKAIHIGN_00946 2.1e-79 marR K Transcriptional regulator
OKAIHIGN_00947 1.7e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OKAIHIGN_00948 2e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OKAIHIGN_00949 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
OKAIHIGN_00950 1.2e-121 IQ reductase
OKAIHIGN_00951 1.2e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OKAIHIGN_00952 6.7e-72 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OKAIHIGN_00953 5.5e-71 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
OKAIHIGN_00954 8.6e-265 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
OKAIHIGN_00955 4.7e-154 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OKAIHIGN_00956 1.7e-142 accA 2.1.3.15, 6.4.1.2 I alpha subunit
OKAIHIGN_00957 1.2e-119 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OKAIHIGN_00958 1e-142 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OKAIHIGN_00959 2.2e-85 bioY S BioY family
OKAIHIGN_00960 4.4e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
OKAIHIGN_00961 1.3e-90 entB 3.5.1.19 Q Isochorismatase family
OKAIHIGN_00962 7.9e-109 S NAD(P)H-binding
OKAIHIGN_00963 2.4e-31 K helix_turn_helix, mercury resistance
OKAIHIGN_00964 3.2e-22 papX3 K Transcriptional regulator
OKAIHIGN_00965 5.7e-115 ydiC1 EGP Major facilitator Superfamily
OKAIHIGN_00966 1.9e-48 S NADPH-dependent FMN reductase
OKAIHIGN_00967 2.4e-72 S Protein of unknown function (DUF3021)
OKAIHIGN_00968 9.2e-72 K LytTr DNA-binding domain
OKAIHIGN_00969 4.1e-43 merR K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
OKAIHIGN_00970 3e-156 lmrB EGP Major facilitator Superfamily
OKAIHIGN_00971 5.8e-41 N PFAM Uncharacterised protein family UPF0150
OKAIHIGN_00972 3.1e-30 adhR K MerR, DNA binding
OKAIHIGN_00973 6.7e-187 C Aldo/keto reductase family
OKAIHIGN_00974 2.7e-88 pnb C nitroreductase
OKAIHIGN_00975 3.4e-56 K GNAT family
OKAIHIGN_00976 4.8e-295 katA 1.11.1.6 C Belongs to the catalase family
OKAIHIGN_00977 2.1e-102 rimL J Acetyltransferase (GNAT) domain
OKAIHIGN_00978 9e-69
OKAIHIGN_00979 1e-67 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
OKAIHIGN_00980 1.1e-35 K Bacterial regulatory proteins, tetR family
OKAIHIGN_00981 1.2e-146 K Helix-turn-helix
OKAIHIGN_00982 5.5e-278 yjeM E Amino Acid
OKAIHIGN_00983 1.3e-273 pipD E Dipeptidase
OKAIHIGN_00984 4.5e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OKAIHIGN_00985 1.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
OKAIHIGN_00986 4.9e-295 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OKAIHIGN_00987 1.3e-49 S Protein of unknown function (DUF2975)
OKAIHIGN_00988 2.4e-27 yozG K Transcriptional regulator
OKAIHIGN_00989 9.2e-199
OKAIHIGN_00990 4.5e-98
OKAIHIGN_00991 7.8e-215 ica2 GT2 M Glycosyl transferase family group 2
OKAIHIGN_00992 3.5e-60 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
OKAIHIGN_00993 2.4e-207 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OKAIHIGN_00994 0.0 yhcA V ABC transporter, ATP-binding protein
OKAIHIGN_00995 2.1e-100 bm3R1 K Psort location Cytoplasmic, score
OKAIHIGN_00996 1.9e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OKAIHIGN_00997 6.4e-38 S Mor transcription activator family
OKAIHIGN_00998 2.9e-41 S Mor transcription activator family
OKAIHIGN_00999 1.5e-121 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OKAIHIGN_01000 6.1e-20 S Mor transcription activator family
OKAIHIGN_01001 8.9e-125 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
OKAIHIGN_01002 9.2e-188 ybhR V ABC transporter
OKAIHIGN_01003 1.3e-111 K Bacterial regulatory proteins, tetR family
OKAIHIGN_01004 4e-177 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
OKAIHIGN_01005 2e-58 yqkB S Belongs to the HesB IscA family
OKAIHIGN_01006 2.1e-200 yjcE P Sodium proton antiporter
OKAIHIGN_01007 2.3e-47 yeaN P Major Facilitator Superfamily
OKAIHIGN_01008 0.0 kup P Transport of potassium into the cell
OKAIHIGN_01009 1.4e-181 C Zinc-binding dehydrogenase
OKAIHIGN_01010 1.1e-99 1.1.1.219 GM Male sterility protein
OKAIHIGN_01011 4.2e-77 K helix_turn_helix, mercury resistance
OKAIHIGN_01012 7.2e-66 K MarR family
OKAIHIGN_01013 8.2e-48 S Uncharacterized protein conserved in bacteria (DUF2316)
OKAIHIGN_01014 5.1e-198 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
OKAIHIGN_01015 1.1e-76 K Transcriptional regulator
OKAIHIGN_01016 3.8e-162 akr5f 1.1.1.346 S reductase
OKAIHIGN_01017 1.8e-164 S Oxidoreductase, aldo keto reductase family protein
OKAIHIGN_01018 8.6e-81
OKAIHIGN_01019 6.2e-213 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
OKAIHIGN_01020 7.3e-152 yitU 3.1.3.104 S hydrolase
OKAIHIGN_01021 2e-266 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
OKAIHIGN_01022 3.4e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OKAIHIGN_01023 2.4e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
OKAIHIGN_01024 2.9e-171 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
OKAIHIGN_01025 2e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
OKAIHIGN_01026 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OKAIHIGN_01027 2.6e-83 ypmB S Protein conserved in bacteria
OKAIHIGN_01028 9.4e-209 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OKAIHIGN_01029 7.2e-124 dnaD L Replication initiation and membrane attachment
OKAIHIGN_01030 3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
OKAIHIGN_01031 1.7e-60 P Rhodanese Homology Domain
OKAIHIGN_01032 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
OKAIHIGN_01033 4.2e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OKAIHIGN_01034 2.1e-105 ypsA S Belongs to the UPF0398 family
OKAIHIGN_01035 6.4e-28 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OKAIHIGN_01037 3e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OKAIHIGN_01038 3.7e-66 FG Scavenger mRNA decapping enzyme C-term binding
OKAIHIGN_01039 5.9e-247 amtB P ammonium transporter
OKAIHIGN_01040 4.8e-28
OKAIHIGN_01041 1.4e-82 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
OKAIHIGN_01042 4.8e-52
OKAIHIGN_01043 1.3e-122 S CAAX protease self-immunity
OKAIHIGN_01044 7.7e-86 K Bacterial regulatory proteins, tetR family
OKAIHIGN_01045 1.6e-111 XK27_02070 S Nitroreductase family
OKAIHIGN_01046 2.6e-208 yurR 1.4.5.1 E FAD dependent oxidoreductase
OKAIHIGN_01047 6.8e-66 rnhA 3.1.26.4 L Ribonuclease HI
OKAIHIGN_01048 1.1e-55 esbA S Family of unknown function (DUF5322)
OKAIHIGN_01049 7.5e-305 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
OKAIHIGN_01050 5.6e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OKAIHIGN_01051 3.6e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OKAIHIGN_01052 6.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OKAIHIGN_01053 4.4e-205 carA 6.3.5.5 F Belongs to the CarA family
OKAIHIGN_01054 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
OKAIHIGN_01055 0.0 FbpA K Fibronectin-binding protein
OKAIHIGN_01056 6.3e-70 K Transcriptional regulator
OKAIHIGN_01057 7.1e-197 npp S type I phosphodiesterase nucleotide pyrophosphatase
OKAIHIGN_01058 7.6e-233 yxiO S Vacuole effluxer Atg22 like
OKAIHIGN_01059 7.8e-160 degV S EDD domain protein, DegV family
OKAIHIGN_01060 4.1e-87 folT S ECF transporter, substrate-specific component
OKAIHIGN_01061 1.9e-74 gtcA S Teichoic acid glycosylation protein
OKAIHIGN_01062 7.7e-83 ysaA V VanZ like family
OKAIHIGN_01063 2.2e-90 V VanZ like family
OKAIHIGN_01064 2.5e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OKAIHIGN_01065 4e-142 mta K helix_turn_helix, mercury resistance
OKAIHIGN_01066 2.6e-169 C Zinc-binding dehydrogenase
OKAIHIGN_01067 9.9e-84 C Zinc-binding dehydrogenase
OKAIHIGN_01068 1.5e-10 yxcB K Transcriptional regulator C-terminal region
OKAIHIGN_01070 8.6e-67 IQ KR domain
OKAIHIGN_01071 5.2e-72 S membrane transporter protein
OKAIHIGN_01072 4.7e-46 S Phosphatidylethanolamine-binding protein
OKAIHIGN_01073 1.8e-35 yobS K transcriptional regulator
OKAIHIGN_01074 2.9e-120 Q Methyltransferase domain
OKAIHIGN_01075 5.6e-120 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OKAIHIGN_01076 7.9e-121 yneE K Transcriptional regulator
OKAIHIGN_01078 1.5e-74 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OKAIHIGN_01079 1.4e-69 K Transcriptional regulator
OKAIHIGN_01080 1.9e-140 K Bacterial regulatory helix-turn-helix protein, lysR family
OKAIHIGN_01081 1.8e-120 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OKAIHIGN_01082 1.2e-93 GM NAD(P)H-binding
OKAIHIGN_01083 7.5e-59 S Phosphatidylethanolamine-binding protein
OKAIHIGN_01084 2.5e-43 I sulfurtransferase activity
OKAIHIGN_01085 1.5e-201 S membrane
OKAIHIGN_01086 1.6e-65 K Bacterial regulatory proteins, tetR family
OKAIHIGN_01087 2.8e-83 G Glycosyl hydrolases family 15
OKAIHIGN_01088 1.8e-211 G of the major facilitator superfamily
OKAIHIGN_01089 6.4e-68 ccpA K Psort location Cytoplasmic, score
OKAIHIGN_01090 3.6e-199 xerS L Belongs to the 'phage' integrase family
OKAIHIGN_01091 3.6e-68 3.6.1.55 F NUDIX domain
OKAIHIGN_01092 1.4e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OKAIHIGN_01093 1.3e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OKAIHIGN_01094 5.4e-101 zmp1 O PFAM peptidase M10A and M12B, matrixin and adamalysin
OKAIHIGN_01095 8.3e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
OKAIHIGN_01096 1.6e-182 K Transcriptional regulator
OKAIHIGN_01097 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OKAIHIGN_01098 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OKAIHIGN_01099 3.2e-99 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OKAIHIGN_01100 1.2e-168 lacX 5.1.3.3 G Aldose 1-epimerase
OKAIHIGN_01101 1.8e-262 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OKAIHIGN_01102 1.8e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OKAIHIGN_01103 5.8e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
OKAIHIGN_01104 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OKAIHIGN_01105 2.2e-165 dprA LU DNA protecting protein DprA
OKAIHIGN_01106 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OKAIHIGN_01107 6.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OKAIHIGN_01108 6.3e-108 vrlS L helicase superfamily c-terminal domain
OKAIHIGN_01109 1.3e-34 vrlR S Domain of unknown function (DUF1837)
OKAIHIGN_01110 2e-61 S AAA ATPase domain
OKAIHIGN_01111 5e-173
OKAIHIGN_01112 3.8e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OKAIHIGN_01113 6.5e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
OKAIHIGN_01114 5.8e-280 E amino acid
OKAIHIGN_01115 8.9e-107 dhaS K Bacterial regulatory proteins, tetR family
OKAIHIGN_01116 2.6e-56 ywnB S NAD(P)H-binding
OKAIHIGN_01117 1.9e-10 yobS K transcriptional regulator
OKAIHIGN_01118 4.8e-73 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OKAIHIGN_01121 3e-207 lmrP E Major Facilitator Superfamily
OKAIHIGN_01122 1.2e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OKAIHIGN_01123 1.8e-289 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OKAIHIGN_01124 6.7e-165
OKAIHIGN_01125 4.2e-95 S Protein of unknown function (DUF1097)
OKAIHIGN_01126 8.6e-265 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OKAIHIGN_01127 1.1e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OKAIHIGN_01128 8.9e-57 ydiI Q Thioesterase superfamily
OKAIHIGN_01129 3.7e-85 yybC S Protein of unknown function (DUF2798)
OKAIHIGN_01130 4.5e-100 GBS0088 S Nucleotidyltransferase
OKAIHIGN_01131 6.2e-134
OKAIHIGN_01132 5.7e-55 S protein encoded in hypervariable junctions of pilus gene clusters
OKAIHIGN_01133 2.2e-130 qmcA O prohibitin homologues
OKAIHIGN_01134 7.3e-231 XK27_06930 S ABC-2 family transporter protein
OKAIHIGN_01135 1.1e-113 K Bacterial regulatory proteins, tetR family
OKAIHIGN_01136 3.5e-302 E Bacterial extracellular solute-binding proteins, family 5 Middle
OKAIHIGN_01137 2.7e-75 gtrA S GtrA-like protein
OKAIHIGN_01138 7.7e-76 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
OKAIHIGN_01139 7.1e-85 cadD P Cadmium resistance transporter
OKAIHIGN_01141 4.9e-97 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
OKAIHIGN_01142 1.7e-176 draG 3.2.2.24 O ADP-ribosylglycohydrolase
OKAIHIGN_01143 4.3e-143 nlhH I Esterase
OKAIHIGN_01144 1.3e-35 mgrA K helix_turn_helix multiple antibiotic resistance protein
OKAIHIGN_01145 1.3e-79 argO S LysE type translocator
OKAIHIGN_01146 1.3e-118 yfjF U Sugar (and other) transporter
OKAIHIGN_01149 1.3e-12 L PFAM Integrase, catalytic core
OKAIHIGN_01150 7.6e-37 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
OKAIHIGN_01151 5e-38 gtrA S GtrA-like protein
OKAIHIGN_01152 1.6e-12 L Transposase and inactivated derivatives, IS30 family
OKAIHIGN_01153 3.9e-81 pva1 3.5.1.24 M Choloylglycine hydrolase
OKAIHIGN_01154 4.1e-211 gadB 4.1.1.15 E Converts internalized glutamate to GABA and increases the internal pH. Involved in glutamate-dependent acid resistance
OKAIHIGN_01155 1e-90 pip1 V domain protein
OKAIHIGN_01156 1.8e-104 pip1 V domain protein
OKAIHIGN_01158 4.8e-22 S response to pH
OKAIHIGN_01159 8.1e-151 gadC E Amino acid permease
OKAIHIGN_01161 1.5e-141 D CobQ CobB MinD ParA nucleotide binding domain protein
OKAIHIGN_01162 3.5e-37 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OKAIHIGN_01163 9.2e-07 K MarR family
OKAIHIGN_01174 3e-35 S Protein of unknown function (DUF3102)
OKAIHIGN_01175 1.6e-107 K Primase C terminal 1 (PriCT-1)
OKAIHIGN_01176 2.4e-98 D Cellulose biosynthesis protein BcsQ
OKAIHIGN_01177 6.1e-45
OKAIHIGN_01179 5.1e-55 L recombinase activity
OKAIHIGN_01180 4e-63 L 4.5 Transposon and IS
OKAIHIGN_01181 1.9e-23 tnp L DDE domain
OKAIHIGN_01182 3.7e-67 tnp L DDE domain
OKAIHIGN_01183 1e-10
OKAIHIGN_01187 6.8e-18 S Short repeat of unknown function (DUF308)
OKAIHIGN_01188 2.5e-91 tenA 3.5.99.2 K TENA THI-4 family protein
OKAIHIGN_01189 3.8e-106 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OKAIHIGN_01190 3.5e-97 L Transposase and inactivated derivatives, IS30 family
OKAIHIGN_01191 1.1e-161 P Natural resistance-associated macrophage protein
OKAIHIGN_01192 3.1e-235 sufB O assembly protein SufB
OKAIHIGN_01193 1.4e-46 nifU C involved in Fe-S cluster formation
OKAIHIGN_01194 8.3e-173 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OKAIHIGN_01195 4.2e-105 sufD O ABC-type transport system involved in Fe-S cluster assembly, permease component
OKAIHIGN_01196 9e-125 sufC O FeS assembly ATPase SufC
OKAIHIGN_01197 1.6e-95 nrdG 1.97.1.4 C Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OKAIHIGN_01198 0.0 nrdD 1.1.98.6 F Oxygen-sensitive ribonucleoside-triphosphate reductase
OKAIHIGN_01199 1.4e-16
OKAIHIGN_01200 1.7e-71 M Mycoplasma protein of unknown function, DUF285
OKAIHIGN_01205 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
OKAIHIGN_01206 3.3e-75 K Acetyltransferase (GNAT) domain
OKAIHIGN_01207 5e-167
OKAIHIGN_01208 5.6e-108 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OKAIHIGN_01210 5.1e-08 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
OKAIHIGN_01211 3.3e-22 S Mor transcription activator family
OKAIHIGN_01212 7.6e-143 ydhO 3.4.14.13 M NlpC/P60 family
OKAIHIGN_01213 8.7e-219 EGP Major Facilitator Superfamily
OKAIHIGN_01214 9.7e-85 GM NAD(P)H-binding
OKAIHIGN_01215 8.8e-119 lsa S ABC transporter
OKAIHIGN_01216 6.8e-64 int L Belongs to the 'phage' integrase family
OKAIHIGN_01218 5.1e-47
OKAIHIGN_01219 4.6e-83 V VanZ like family
OKAIHIGN_01220 9.4e-83 ohrR K Transcriptional regulator
OKAIHIGN_01221 5.6e-121 S CAAX protease self-immunity
OKAIHIGN_01222 1.5e-36
OKAIHIGN_01223 4.3e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKAIHIGN_01224 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
OKAIHIGN_01225 2.8e-101 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
OKAIHIGN_01226 7.7e-143 S haloacid dehalogenase-like hydrolase
OKAIHIGN_01227 4.5e-120 dck 2.7.1.74 F Deoxynucleoside kinase
OKAIHIGN_01228 1.8e-56 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
OKAIHIGN_01229 1.1e-246 bmr3 EGP Major facilitator Superfamily
OKAIHIGN_01230 3.7e-213 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OKAIHIGN_01231 9.6e-108
OKAIHIGN_01232 1.2e-44
OKAIHIGN_01233 3e-96
OKAIHIGN_01234 1.7e-51 ybjQ S Belongs to the UPF0145 family
OKAIHIGN_01235 8.1e-83 zmp2 O Zinc-dependent metalloprotease
OKAIHIGN_01237 1.8e-153 S Uncharacterised protein, DegV family COG1307
OKAIHIGN_01238 6.4e-241 mntH P H( )-stimulated, divalent metal cation uptake system
OKAIHIGN_01239 8e-129 IQ reductase
OKAIHIGN_01240 1.4e-39
OKAIHIGN_01241 4.2e-81 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
OKAIHIGN_01242 2.2e-110 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
OKAIHIGN_01243 7e-128 kdgT P 2-keto-3-deoxygluconate permease
OKAIHIGN_01244 1.2e-138 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKAIHIGN_01245 6.2e-146 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OKAIHIGN_01247 6.2e-10
OKAIHIGN_01248 3.2e-53 kguE 2.7.1.45 G Xylose isomerase-like TIM barrel
OKAIHIGN_01249 1.2e-100 K Bacterial transcriptional regulator
OKAIHIGN_01250 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
OKAIHIGN_01251 1.7e-102 K Bacterial regulatory proteins, tetR family
OKAIHIGN_01252 2.4e-95 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OKAIHIGN_01253 4.2e-228 ndh 1.6.99.3 C NADH dehydrogenase
OKAIHIGN_01254 4.3e-115 ylbE GM NAD(P)H-binding
OKAIHIGN_01255 1.2e-30
OKAIHIGN_01256 8.8e-110 K Transcriptional regulatory protein, C terminal
OKAIHIGN_01260 3.1e-08 CO Thioredoxin
OKAIHIGN_01263 6e-31 S Protein of unknown function (DUF3102)
OKAIHIGN_01264 3.4e-110 K Primase C terminal 1 (PriCT-1)
OKAIHIGN_01265 4.6e-39 soj D Sporulation initiation inhibitor
OKAIHIGN_01269 3.6e-28 M CHAP domain
OKAIHIGN_01270 1.5e-43 trsE S COG0433 Predicted ATPase
OKAIHIGN_01271 4.5e-228 S Protein of unknown function (DUF1524)
OKAIHIGN_01273 9.9e-48 S Protein of unknown function (DUF1722)
OKAIHIGN_01274 0.0 L helicase
OKAIHIGN_01275 1.4e-114 L L COG1961 Site-specific recombinases, DNA invertase Pin homologs
OKAIHIGN_01276 4.1e-35 L Recombinase zinc beta ribbon domain
OKAIHIGN_01278 1.2e-47 L Domain of unknown function (DUF927)
OKAIHIGN_01282 2.6e-20 3.1.3.16 V Protein of unknown function (DUF1643)
OKAIHIGN_01284 1.5e-10 S Mor transcription activator family
OKAIHIGN_01289 1.4e-59 L Transposase and inactivated derivatives, IS30 family
OKAIHIGN_01290 2.1e-107 psaA P Belongs to the bacterial solute-binding protein 9 family
OKAIHIGN_01292 3.3e-32 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OKAIHIGN_01293 2.3e-11 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OKAIHIGN_01295 2.6e-73 M hydrolase, family 25
OKAIHIGN_01296 9e-107 L Transposase and inactivated derivatives, IS30 family
OKAIHIGN_01297 9e-103 tnp L DDE domain
OKAIHIGN_01299 5.6e-44
OKAIHIGN_01300 9.7e-101 tnp L DDE domain
OKAIHIGN_01302 2.7e-81 M Glycosyltransferases, probably involved in cell wall biogenesis
OKAIHIGN_01303 5e-71 U type IV secretory pathway VirB4
OKAIHIGN_01304 2.8e-21
OKAIHIGN_01306 1.1e-25 I mechanosensitive ion channel activity
OKAIHIGN_01307 1.2e-126 U TraM recognition site of TraD and TraG
OKAIHIGN_01309 1.2e-28 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
OKAIHIGN_01310 1.1e-66 M MucBP domain
OKAIHIGN_01311 3.1e-220 L Transposase
OKAIHIGN_01312 9.2e-21 L PFAM Integrase, catalytic core
OKAIHIGN_01313 1.7e-246 T PhoQ Sensor
OKAIHIGN_01314 6.5e-43
OKAIHIGN_01315 4.1e-66
OKAIHIGN_01316 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OKAIHIGN_01317 1.6e-150 corA P CorA-like Mg2+ transporter protein
OKAIHIGN_01318 7.3e-138 pnuC H nicotinamide mononucleotide transporter
OKAIHIGN_01319 5.6e-56 K Winged helix DNA-binding domain
OKAIHIGN_01320 0.0 malL 3.2.1.10, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G Alpha amylase, catalytic domain protein
OKAIHIGN_01321 2.4e-121 yclH V ABC transporter
OKAIHIGN_01322 5.5e-166 yclI V FtsX-like permease family
OKAIHIGN_01323 3.1e-196 yubA S AI-2E family transporter
OKAIHIGN_01324 6.9e-105
OKAIHIGN_01325 2.9e-246 M hydrolase, family 25
OKAIHIGN_01326 2.2e-193 ykoT GT2 M Glycosyl transferase family 2
OKAIHIGN_01327 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OKAIHIGN_01328 1.2e-109 M Protein of unknown function (DUF3737)
OKAIHIGN_01329 3.5e-224 patB 4.4.1.8 E Aminotransferase, class I
OKAIHIGN_01330 5.5e-183 yfeX P Peroxidase
OKAIHIGN_01331 5e-221 mdtG EGP Major facilitator Superfamily
OKAIHIGN_01332 4.6e-45
OKAIHIGN_01333 2.8e-224 opuCA E ABC transporter, ATP-binding protein
OKAIHIGN_01334 8e-106 opuCB E ABC transporter permease
OKAIHIGN_01335 2e-177 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OKAIHIGN_01336 2.1e-109 opuCD P Binding-protein-dependent transport system inner membrane component
OKAIHIGN_01337 8.7e-211
OKAIHIGN_01338 1.9e-262
OKAIHIGN_01339 5e-66 S Tautomerase enzyme
OKAIHIGN_01340 0.0 uvrA2 L ABC transporter
OKAIHIGN_01341 4.6e-99 S Protein of unknown function (DUF1440)
OKAIHIGN_01342 8.1e-249 xylP1 G MFS/sugar transport protein
OKAIHIGN_01343 2.4e-94 K helix_turn_helix multiple antibiotic resistance protein
OKAIHIGN_01344 1.8e-37
OKAIHIGN_01345 3.5e-67 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OKAIHIGN_01346 2.4e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
OKAIHIGN_01347 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
OKAIHIGN_01348 9.5e-122
OKAIHIGN_01349 0.0 oatA I Acyltransferase
OKAIHIGN_01350 2.5e-189 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OKAIHIGN_01351 1.1e-158 xerD L Phage integrase, N-terminal SAM-like domain
OKAIHIGN_01352 9.6e-155 yxkH G Polysaccharide deacetylase
OKAIHIGN_01354 2.5e-67 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
OKAIHIGN_01355 0.0 ctpA 3.6.3.54 P P-type ATPase
OKAIHIGN_01356 8.4e-159 S reductase
OKAIHIGN_01357 2e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OKAIHIGN_01358 1.7e-78 copR K Copper transport repressor CopY TcrY
OKAIHIGN_01359 0.0 copB 3.6.3.4 P P-type ATPase
OKAIHIGN_01360 1.3e-168 EG EamA-like transporter family
OKAIHIGN_01361 5e-119 S Elongation factor G-binding protein, N-terminal
OKAIHIGN_01362 1.3e-97 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
OKAIHIGN_01363 3.3e-154
OKAIHIGN_01364 7.5e-277 pipD E Dipeptidase
OKAIHIGN_01365 0.0 pacL1 P P-type ATPase
OKAIHIGN_01366 9.2e-73 K MarR family
OKAIHIGN_01367 4.9e-99 S NADPH-dependent FMN reductase
OKAIHIGN_01368 3.5e-197 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
OKAIHIGN_01369 6.4e-12 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OKAIHIGN_01370 7.2e-270 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OKAIHIGN_01371 1.2e-163 opuBA E ABC transporter, ATP-binding protein
OKAIHIGN_01372 4.4e-68 lrpA K AsnC family
OKAIHIGN_01373 3e-187 adhP 1.1.1.1 C alcohol dehydrogenase
OKAIHIGN_01374 3.7e-224 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
OKAIHIGN_01375 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
OKAIHIGN_01376 1.9e-64 S WxL domain surface cell wall-binding
OKAIHIGN_01377 7.1e-113
OKAIHIGN_01378 6.2e-241 yifK E Amino acid permease
OKAIHIGN_01379 2.8e-96 K Acetyltransferase (GNAT) domain
OKAIHIGN_01380 1.6e-71 fld C Flavodoxin
OKAIHIGN_01381 5.4e-220 fabV 1.3.1.44, 1.3.1.9 I NAD(P)H binding domain of trans-2-enoyl-CoA reductase
OKAIHIGN_01382 1.9e-186 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OKAIHIGN_01383 3.5e-113 S Putative adhesin
OKAIHIGN_01384 6.3e-74 XK27_06920 S Protein of unknown function (DUF1700)
OKAIHIGN_01385 2.7e-54 K Transcriptional regulator PadR-like family
OKAIHIGN_01386 3.8e-104 pncA Q Isochorismatase family
OKAIHIGN_01387 1.4e-216 srfJ1 3.2.1.45 GH30 M Belongs to the glycosyl hydrolase 30 family
OKAIHIGN_01388 5e-147 blt G MFS/sugar transport protein
OKAIHIGN_01389 6.6e-247 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
OKAIHIGN_01390 3.4e-78 K AraC-like ligand binding domain
OKAIHIGN_01391 1.9e-242 3.2.1.21 GH3 G Fibronectin type III-like domain
OKAIHIGN_01392 2.4e-161 G Peptidase_C39 like family
OKAIHIGN_01393 4.5e-199 M NlpC/P60 family
OKAIHIGN_01394 2.1e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OKAIHIGN_01395 7e-113 magIII L Base excision DNA repair protein, HhH-GPD family
OKAIHIGN_01396 3.7e-38
OKAIHIGN_01397 6.9e-133 puuD S peptidase C26
OKAIHIGN_01398 2.9e-119 S Membrane
OKAIHIGN_01399 0.0 O Pro-kumamolisin, activation domain
OKAIHIGN_01400 1.8e-164 I Alpha beta
OKAIHIGN_01401 1.1e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
OKAIHIGN_01402 4.3e-180 D Alpha beta
OKAIHIGN_01403 4.3e-98 fadR K Bacterial regulatory proteins, tetR family
OKAIHIGN_01404 2e-121 GM NmrA-like family
OKAIHIGN_01405 2.3e-233 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
OKAIHIGN_01406 9.8e-26 GM NmrA-like family
OKAIHIGN_01407 4.6e-241 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OKAIHIGN_01408 3.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OKAIHIGN_01409 3.2e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OKAIHIGN_01410 1.6e-121 XK27_00720 S regulation of response to stimulus
OKAIHIGN_01411 2.4e-276 mntH P H( )-stimulated, divalent metal cation uptake system
OKAIHIGN_01412 1.5e-71 T Universal stress protein family
OKAIHIGN_01413 3.1e-121 sirR K Helix-turn-helix diphteria tox regulatory element
OKAIHIGN_01414 1.6e-89 P Cadmium resistance transporter
OKAIHIGN_01415 1.1e-90
OKAIHIGN_01416 4.6e-73
OKAIHIGN_01417 2.1e-79 yybA 2.3.1.57 K Transcriptional regulator
OKAIHIGN_01418 6.7e-75 elaA S Gnat family
OKAIHIGN_01419 2.2e-185 1.1.1.219 GM Male sterility protein
OKAIHIGN_01420 4.5e-100 K Bacterial regulatory proteins, tetR family
OKAIHIGN_01421 9.9e-83 padR K Virulence activator alpha C-term
OKAIHIGN_01422 3.2e-103 padC Q Phenolic acid decarboxylase
OKAIHIGN_01424 6.4e-84 F NUDIX domain
OKAIHIGN_01426 3.4e-94 wecD K Acetyltransferase (GNAT) family
OKAIHIGN_01427 4e-124 yliE T Putative diguanylate phosphodiesterase
OKAIHIGN_01428 1.4e-101 XK27_06935 K Bacterial regulatory proteins, tetR family
OKAIHIGN_01429 2.7e-175 S ABC-2 family transporter protein
OKAIHIGN_01430 3e-125 malR3 K cheY-homologous receiver domain
OKAIHIGN_01431 1.3e-269 yufL 2.7.13.3 T Single cache domain 3
OKAIHIGN_01432 6e-188 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKAIHIGN_01433 2.3e-190 S Membrane transport protein
OKAIHIGN_01434 3.2e-251 nhaC C Na H antiporter NhaC
OKAIHIGN_01435 1.3e-93 Z012_06855 S Acetyltransferase (GNAT) family
OKAIHIGN_01436 7.5e-70
OKAIHIGN_01437 2.6e-171 C Aldo keto reductase
OKAIHIGN_01438 2.3e-49
OKAIHIGN_01439 3.3e-122 kcsA P Ion channel
OKAIHIGN_01440 1.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
OKAIHIGN_01441 3e-95 yxkA S Phosphatidylethanolamine-binding protein
OKAIHIGN_01442 1.1e-89 uspA T universal stress protein
OKAIHIGN_01443 0.0 S membrane
OKAIHIGN_01444 1e-68 frataxin S Domain of unknown function (DU1801)
OKAIHIGN_01445 3.3e-141 IQ reductase
OKAIHIGN_01446 3.8e-225 xylT EGP Major facilitator Superfamily
OKAIHIGN_01447 2.8e-290 xylB 2.7.1.12, 2.7.1.16, 2.7.1.17 G Xylulose kinase
OKAIHIGN_01448 2.3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
OKAIHIGN_01450 6.2e-18
OKAIHIGN_01451 5.2e-49
OKAIHIGN_01452 5.2e-69
OKAIHIGN_01453 1.6e-196 lplA 6.3.1.20 H Lipoate-protein ligase
OKAIHIGN_01454 1.6e-79 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
OKAIHIGN_01455 2.4e-192 oppD P Belongs to the ABC transporter superfamily
OKAIHIGN_01456 9.3e-178 oppF P Belongs to the ABC transporter superfamily
OKAIHIGN_01457 9.8e-180 oppB P ABC transporter permease
OKAIHIGN_01458 1e-173 oppC EP Binding-protein-dependent transport system inner membrane component
OKAIHIGN_01459 0.0 oppA1 E ABC transporter substrate-binding protein
OKAIHIGN_01460 2.4e-50 K transcriptional regulator
OKAIHIGN_01461 1.1e-165 norB EGP Major Facilitator
OKAIHIGN_01462 5.3e-52 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OKAIHIGN_01463 2.8e-76 uspA T universal stress protein
OKAIHIGN_01464 5.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OKAIHIGN_01466 8.8e-128 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
OKAIHIGN_01467 3.7e-209 2.1.1.80, 2.7.13.3, 3.1.1.61 T protein histidine kinase activity
OKAIHIGN_01468 1.6e-212 2.7.13.3 T GHKL domain
OKAIHIGN_01469 2.6e-135 plnC K LytTr DNA-binding domain
OKAIHIGN_01470 5.1e-72
OKAIHIGN_01471 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OKAIHIGN_01472 2e-107 O Zinc-dependent metalloprotease
OKAIHIGN_01473 4.4e-132 gntR1 K UbiC transcription regulator-associated domain protein
OKAIHIGN_01474 3.2e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OKAIHIGN_01475 3.5e-115
OKAIHIGN_01476 2.2e-64 S Leucine-rich repeat (LRR) protein
OKAIHIGN_01477 2.2e-19 K Helix-turn-helix XRE-family like proteins
OKAIHIGN_01478 6.2e-19 S Protein of unknown function (DUF3278)
OKAIHIGN_01479 9.6e-253 EGP Major facilitator Superfamily
OKAIHIGN_01481 6.2e-227 S module of peptide synthetase
OKAIHIGN_01482 4e-294 uxaC 5.3.1.12 G glucuronate isomerase
OKAIHIGN_01483 4.8e-309 5.1.2.7 S tagaturonate epimerase
OKAIHIGN_01484 1.8e-278 yjmB G MFS/sugar transport protein
OKAIHIGN_01485 2.4e-184 exuR K Periplasmic binding protein domain
OKAIHIGN_01486 1.6e-207 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
OKAIHIGN_01487 1.1e-127 kdgR K FCD domain
OKAIHIGN_01488 5.1e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
OKAIHIGN_01489 1.3e-303 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
OKAIHIGN_01490 5.3e-189 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKAIHIGN_01491 6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
OKAIHIGN_01492 8.7e-167 yqhA G Aldose 1-epimerase
OKAIHIGN_01493 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
OKAIHIGN_01494 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
OKAIHIGN_01495 0.0 yicI 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
OKAIHIGN_01496 1.4e-259 gph G MFS/sugar transport protein
OKAIHIGN_01497 7e-283 uxaC 5.3.1.12 G glucuronate isomerase
OKAIHIGN_01498 5.2e-248 V Polysaccharide biosynthesis C-terminal domain
OKAIHIGN_01499 5.6e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
OKAIHIGN_01500 4.2e-169 yjjC V ABC transporter
OKAIHIGN_01501 1.9e-284 M Exporter of polyketide antibiotics
OKAIHIGN_01502 3.6e-53 DR0488 S 3D domain
OKAIHIGN_01503 1.5e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OKAIHIGN_01504 7.2e-178 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
OKAIHIGN_01505 1.9e-166 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OKAIHIGN_01506 2.3e-93 K Bacterial regulatory proteins, tetR family
OKAIHIGN_01508 2.2e-147 picA 3.2.1.67 G Glycosyl hydrolases family 28
OKAIHIGN_01509 1.8e-92 G Xylose isomerase-like TIM barrel
OKAIHIGN_01510 5.6e-246 melB1_1 G MFS/sugar transport protein
OKAIHIGN_01511 4.1e-161 yteR 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
OKAIHIGN_01512 6.5e-57 M LysM domain
OKAIHIGN_01514 6e-56 M LysM domain protein
OKAIHIGN_01515 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Leucine-rich repeat (LRR) protein
OKAIHIGN_01516 5.9e-47 M LysM domain protein
OKAIHIGN_01517 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
OKAIHIGN_01518 0.0 glpQ 3.1.4.46 C phosphodiesterase
OKAIHIGN_01519 2.2e-93 M1-874 K Domain of unknown function (DUF1836)
OKAIHIGN_01520 0.0 yfgQ P E1-E2 ATPase
OKAIHIGN_01522 3.6e-162 ytbE 1.1.1.346 S Aldo keto reductase
OKAIHIGN_01523 2e-256 yjeM E Amino Acid
OKAIHIGN_01524 3.5e-73 hsp O Belongs to the small heat shock protein (HSP20) family
OKAIHIGN_01525 7.6e-61
OKAIHIGN_01526 3.3e-242 yhdP S Transporter associated domain
OKAIHIGN_01527 1.8e-105 yneD S Enoyl-(Acyl carrier protein) reductase
OKAIHIGN_01528 7.6e-52 K transcriptional regulator
OKAIHIGN_01529 5.2e-173 K Transcriptional regulator, LacI family
OKAIHIGN_01530 7.7e-143 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OKAIHIGN_01532 1.7e-249 lmrB EGP Major facilitator Superfamily
OKAIHIGN_01533 3.6e-229 S ATPases associated with a variety of cellular activities
OKAIHIGN_01534 4.5e-85 nrdI F Belongs to the NrdI family
OKAIHIGN_01535 4.7e-129 nfrA 1.5.1.39 C nitroreductase
OKAIHIGN_01536 2.7e-27 K Bacterial regulatory proteins, tetR family
OKAIHIGN_01537 3.8e-90 emrY EGP Major facilitator Superfamily
OKAIHIGN_01538 7e-38 ywnB S NAD(P)H-binding
OKAIHIGN_01539 7.1e-245 glpT G Major Facilitator Superfamily
OKAIHIGN_01540 2.3e-215 yttB EGP Major facilitator Superfamily
OKAIHIGN_01541 1.2e-88
OKAIHIGN_01542 8.4e-159 1.1.1.65 C Aldo keto reductase
OKAIHIGN_01543 7.9e-202 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
OKAIHIGN_01544 7.4e-66 K Bacterial regulatory proteins, tetR family
OKAIHIGN_01545 5.5e-155 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
OKAIHIGN_01546 2.3e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OKAIHIGN_01547 4.5e-22
OKAIHIGN_01548 7e-43 elaA S Gnat family
OKAIHIGN_01549 4.8e-70 K Transcriptional regulator
OKAIHIGN_01550 1.9e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OKAIHIGN_01553 2.7e-69 K Helix-turn-helix XRE-family like proteins
OKAIHIGN_01554 3.7e-44
OKAIHIGN_01555 4.6e-109 ylbE GM NAD(P)H-binding
OKAIHIGN_01556 7.2e-56
OKAIHIGN_01557 5.9e-100 ahpC 1.11.1.15 O Peroxiredoxin
OKAIHIGN_01558 6.4e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OKAIHIGN_01559 1.8e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OKAIHIGN_01560 3.6e-251 yxbA 6.3.1.12 S ATP-grasp enzyme
OKAIHIGN_01561 0.0 asnB 6.3.5.4 E Asparagine synthase
OKAIHIGN_01562 3.1e-119 ntcA2 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
OKAIHIGN_01563 5.5e-272 pipD E Peptidase family C69
OKAIHIGN_01564 1.3e-37
OKAIHIGN_01565 0.0
OKAIHIGN_01566 4.2e-50 S Leucine-rich repeat (LRR) protein
OKAIHIGN_01568 2.2e-68 S HNH endonuclease
OKAIHIGN_01570 1.2e-36 3.2.1.17 M hydrolase, family 25
OKAIHIGN_01572 2.1e-10
OKAIHIGN_01573 7.1e-102 soj D CobQ CobB MinD ParA nucleotide binding domain protein
OKAIHIGN_01575 7.4e-42 K Helix-turn-helix XRE-family like proteins
OKAIHIGN_01583 1.7e-10 XK27_12570 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OKAIHIGN_01584 5.1e-61 XK27_12570 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OKAIHIGN_01586 3.2e-106 L Transposase and inactivated derivatives IS30 family
OKAIHIGN_01588 5.7e-39
OKAIHIGN_01589 6.3e-87 3.2.1.17 M hydrolase, family 25
OKAIHIGN_01591 3.6e-16 S Family of unknown function (DUF5388)
OKAIHIGN_01592 3.6e-29
OKAIHIGN_01593 2.2e-113 soj D AAA domain
OKAIHIGN_01594 1e-39
OKAIHIGN_01595 0.0 V Type II restriction enzyme, methylase subunits
OKAIHIGN_01596 3.4e-40 K Helix-turn-helix domain
OKAIHIGN_01597 7.1e-63 S Phage derived protein Gp49-like (DUF891)
OKAIHIGN_01598 1.2e-44 S SEFIR domain
OKAIHIGN_01599 8e-103 mesE M Transport protein ComB
OKAIHIGN_01600 4.2e-55 L Psort location Cytoplasmic, score
OKAIHIGN_01601 2.6e-52 L Psort location Cytoplasmic, score
OKAIHIGN_01602 1.6e-12
OKAIHIGN_01603 5.7e-81 XK27_12570 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OKAIHIGN_01607 2.6e-107 S MobA/MobL family
OKAIHIGN_01609 2.9e-08
OKAIHIGN_01611 3.4e-33 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OKAIHIGN_01612 1.2e-57 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OKAIHIGN_01613 4.4e-198 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OKAIHIGN_01614 8e-116 S Bacterial membrane protein, YfhO
OKAIHIGN_01617 3.9e-103 soj D COG1192 ATPases involved in chromosome partitioning
OKAIHIGN_01620 8.5e-26 3.2.1.17 M hydrolase, family 25
OKAIHIGN_01621 6.6e-18 anmK 2.3.1.128 J Acetyltransferase (GNAT) domain
OKAIHIGN_01622 9.5e-78 K Acetyltransferase (GNAT) domain
OKAIHIGN_01624 2.5e-18 L Recombinase zinc beta ribbon domain
OKAIHIGN_01626 7.6e-20 3.1.3.16 V Protein of unknown function (DUF1643)
OKAIHIGN_01628 1.1e-10 S Mor transcription activator family
OKAIHIGN_01629 1.3e-38
OKAIHIGN_01630 8.6e-62 S MucBP domain
OKAIHIGN_01631 1e-81 S 3-demethylubiquinone-9 3-methyltransferase
OKAIHIGN_01632 9.1e-115 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
OKAIHIGN_01633 6.2e-264 U Belongs to the BCCT transporter (TC 2.A.15) family
OKAIHIGN_01634 2.3e-78 usp1 T Universal stress protein family
OKAIHIGN_01635 3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S HAD-hyrolase-like
OKAIHIGN_01636 7.5e-70 yeaO S Protein of unknown function, DUF488
OKAIHIGN_01637 1.8e-118 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OKAIHIGN_01638 3.2e-158 hipB K Helix-turn-helix
OKAIHIGN_01639 4.8e-139 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OKAIHIGN_01640 2.5e-152 map 3.4.11.18 E Methionine Aminopeptidase
OKAIHIGN_01641 2.3e-23
OKAIHIGN_01642 5e-241 EGP Major facilitator Superfamily
OKAIHIGN_01643 1.1e-80 6.3.3.2 S ASCH
OKAIHIGN_01644 8.5e-132 IQ Enoyl-(Acyl carrier protein) reductase
OKAIHIGN_01645 1.5e-126 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OKAIHIGN_01646 4e-186 oxlT G Major Facilitator Superfamily
OKAIHIGN_01647 1.9e-76 K Transcriptional regulator, LysR family
OKAIHIGN_01648 0.0 oppD EP Psort location Cytoplasmic, score
OKAIHIGN_01649 5.4e-124 hchA 3.5.1.124 S DJ-1/PfpI family
OKAIHIGN_01650 3.2e-53 K Transcriptional
OKAIHIGN_01651 6.2e-185 1.1.1.1 C nadph quinone reductase
OKAIHIGN_01652 6.6e-176 etfA C Electron transfer flavoprotein FAD-binding domain
OKAIHIGN_01653 3.2e-144 etfB C Electron transfer flavoprotein domain
OKAIHIGN_01654 2.2e-207 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
OKAIHIGN_01655 1.4e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
OKAIHIGN_01656 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
OKAIHIGN_01657 2.6e-36
OKAIHIGN_01658 1.1e-211 gph G Transporter
OKAIHIGN_01659 7.4e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OKAIHIGN_01660 3.1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OKAIHIGN_01661 2.2e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OKAIHIGN_01662 3.7e-185 galR K Transcriptional regulator
OKAIHIGN_01664 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
OKAIHIGN_01666 3.6e-32 V AAA domain, putative AbiEii toxin, Type IV TA system
OKAIHIGN_01668 2.2e-20
OKAIHIGN_01669 9.5e-92 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
OKAIHIGN_01670 0.0 pepO 3.4.24.71 O Peptidase family M13
OKAIHIGN_01671 7.4e-86 K helix_turn_helix multiple antibiotic resistance protein
OKAIHIGN_01672 7.5e-18 S CAAX protease self-immunity
OKAIHIGN_01673 2.7e-131
OKAIHIGN_01674 2.8e-82 uspA T Belongs to the universal stress protein A family
OKAIHIGN_01676 5.8e-200 yibE S overlaps another CDS with the same product name
OKAIHIGN_01677 1e-126 yibF S overlaps another CDS with the same product name
OKAIHIGN_01679 7.1e-179 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
OKAIHIGN_01680 5.7e-91 perR P Belongs to the Fur family
OKAIHIGN_01681 3.7e-112 S VIT family
OKAIHIGN_01682 1.1e-116 S membrane
OKAIHIGN_01683 1.8e-295 E amino acid
OKAIHIGN_01684 5.9e-79 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OKAIHIGN_01685 2.5e-197 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
OKAIHIGN_01686 2e-174 sepS16B
OKAIHIGN_01687 1.2e-123
OKAIHIGN_01688 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
OKAIHIGN_01689 1.8e-43
OKAIHIGN_01690 2.7e-31
OKAIHIGN_01691 1.7e-57
OKAIHIGN_01692 2.4e-156 pstS P Phosphate
OKAIHIGN_01693 1e-168 pstC P probably responsible for the translocation of the substrate across the membrane
OKAIHIGN_01694 3e-143 pstA P Phosphate transport system permease protein PstA
OKAIHIGN_01695 8.3e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OKAIHIGN_01696 3.4e-205 potD P ABC transporter
OKAIHIGN_01697 6.8e-134 potC P ABC transporter permease
OKAIHIGN_01698 3.8e-148 potB P ABC transporter permease
OKAIHIGN_01699 3.1e-209 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
OKAIHIGN_01700 1.6e-18 S Bacteriocin helveticin-J
OKAIHIGN_01701 5.9e-24
OKAIHIGN_01702 5.4e-42 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
OKAIHIGN_01703 2e-103 aroD S Serine hydrolase (FSH1)
OKAIHIGN_01704 1.4e-178 hoxN U High-affinity nickel-transport protein
OKAIHIGN_01705 1.7e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
OKAIHIGN_01706 1.6e-149 larE S NAD synthase
OKAIHIGN_01707 1.2e-227 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
OKAIHIGN_01708 2.3e-131 cpmA S AIR carboxylase
OKAIHIGN_01709 8e-238 larA 5.1.2.1 S Domain of unknown function (DUF2088)
OKAIHIGN_01710 1.7e-125 K Crp-like helix-turn-helix domain
OKAIHIGN_01711 1.4e-280 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
OKAIHIGN_01712 3.8e-68 yqeB S Pyrimidine dimer DNA glycosylase
OKAIHIGN_01713 1.3e-63 S Protein of unknown function (DUF1722)
OKAIHIGN_01714 2.9e-153 1.1.1.2, 1.1.1.307 C Aldo keto reductase
OKAIHIGN_01715 1.9e-153 degV S Uncharacterised protein, DegV family COG1307
OKAIHIGN_01716 1.8e-251 yjjP S Putative threonine/serine exporter
OKAIHIGN_01718 4.7e-211 natB CP ABC-2 family transporter protein
OKAIHIGN_01719 7.2e-169 natA S ABC transporter, ATP-binding protein
OKAIHIGN_01720 5.5e-248 pbuX F xanthine permease
OKAIHIGN_01721 2.9e-25
OKAIHIGN_01722 3e-187 ansA 3.5.1.1 EJ Asparaginase
OKAIHIGN_01723 7.1e-217
OKAIHIGN_01724 5.5e-32
OKAIHIGN_01726 1.1e-08
OKAIHIGN_01727 6.6e-60
OKAIHIGN_01728 1.3e-119 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OKAIHIGN_01729 7.5e-115 P Cobalt transport protein
OKAIHIGN_01730 1.9e-256 P ABC transporter
OKAIHIGN_01731 4.4e-95 S ABC transporter permease
OKAIHIGN_01732 3.4e-169 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OKAIHIGN_01733 1.5e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OKAIHIGN_01734 6.7e-127 cat 2.3.1.28 V Chloramphenicol acetyltransferase
OKAIHIGN_01735 4e-56 S LuxR family transcriptional regulator
OKAIHIGN_01736 2.5e-138 S Uncharacterized protein conserved in bacteria (DUF2087)
OKAIHIGN_01737 5.8e-72 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OKAIHIGN_01738 4.1e-234 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OKAIHIGN_01739 2.8e-151 S Alpha/beta hydrolase of unknown function (DUF915)
OKAIHIGN_01740 6.9e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
OKAIHIGN_01741 1.4e-73
OKAIHIGN_01742 1.6e-07 yvlA
OKAIHIGN_01743 7e-178 iunH2 3.2.2.1, 3.2.2.8 F nucleoside hydrolase
OKAIHIGN_01744 3.9e-190 S Protease prsW family
OKAIHIGN_01745 9.9e-143 S Alpha/beta hydrolase of unknown function (DUF915)
OKAIHIGN_01746 2e-180 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OKAIHIGN_01747 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
OKAIHIGN_01748 9.9e-123 pgm3 G phosphoglycerate mutase family
OKAIHIGN_01749 8.3e-78 yjcF K protein acetylation
OKAIHIGN_01750 1.4e-62 iap CBM50 M NlpC P60 family
OKAIHIGN_01751 6e-82 merR K MerR family regulatory protein
OKAIHIGN_01752 1.6e-91 K Transcriptional regulator PadR-like family
OKAIHIGN_01753 6.6e-257 ydiC1 EGP Major facilitator Superfamily
OKAIHIGN_01754 0.0 ydgH S MMPL family
OKAIHIGN_01755 1.1e-15
OKAIHIGN_01756 4.5e-135 IQ reductase
OKAIHIGN_01757 8.1e-190 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
OKAIHIGN_01758 3.1e-181 S DUF218 domain
OKAIHIGN_01759 3.4e-109 NU mannosyl-glycoprotein
OKAIHIGN_01760 1.7e-243 pbpX1 V SH3-like domain
OKAIHIGN_01761 5.2e-128 terC P integral membrane protein, YkoY family
OKAIHIGN_01762 9.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
OKAIHIGN_01764 7e-219
OKAIHIGN_01766 3.5e-114 S Fn3-like domain
OKAIHIGN_01767 9.2e-55 S WxL domain surface cell wall-binding
OKAIHIGN_01768 9.7e-52 S WxL domain surface cell wall-binding
OKAIHIGN_01769 3.3e-138 XK27_08845 S ABC transporter, ATP-binding protein
OKAIHIGN_01770 3.9e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
OKAIHIGN_01771 2.9e-179 XK27_08835 S ABC transporter
OKAIHIGN_01772 1.1e-161 degV S Uncharacterised protein, DegV family COG1307
OKAIHIGN_01773 9.5e-167 XK27_00670 S ABC transporter
OKAIHIGN_01774 1.7e-168 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
OKAIHIGN_01775 2.2e-120 cmpC S ATPases associated with a variety of cellular activities
OKAIHIGN_01776 1.5e-126 XK27_07075 S CAAX protease self-immunity
OKAIHIGN_01777 4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OKAIHIGN_01778 6.7e-295 S ABC transporter, ATP-binding protein
OKAIHIGN_01779 4.6e-87 M ErfK YbiS YcfS YnhG
OKAIHIGN_01780 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
OKAIHIGN_01781 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
OKAIHIGN_01782 1.2e-242 yfnA E Amino Acid
OKAIHIGN_01783 4.4e-76 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
OKAIHIGN_01784 2.3e-75 gmk2 2.7.4.8 F Guanylate kinase
OKAIHIGN_01785 1.4e-78 zur P Belongs to the Fur family
OKAIHIGN_01786 5.3e-13 3.2.1.14 GH18
OKAIHIGN_01787 1.8e-170
OKAIHIGN_01788 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
OKAIHIGN_01789 1.2e-149 glnH ET ABC transporter substrate-binding protein
OKAIHIGN_01790 1.1e-110 gluC P ABC transporter permease
OKAIHIGN_01791 1.6e-109 glnP P ABC transporter permease
OKAIHIGN_01792 3.5e-225 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OKAIHIGN_01793 6.7e-306 oppA E ABC transporter, substratebinding protein
OKAIHIGN_01794 2.8e-304 oppA E ABC transporter, substratebinding protein
OKAIHIGN_01795 2.2e-152 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKAIHIGN_01796 5.7e-186 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
OKAIHIGN_01797 4.5e-205 oppD P Belongs to the ABC transporter superfamily
OKAIHIGN_01798 1.3e-179 oppF P Belongs to the ABC transporter superfamily
OKAIHIGN_01799 8.5e-119 G phosphoglycerate mutase
OKAIHIGN_01800 2.6e-290 yjbQ P TrkA C-terminal domain protein
OKAIHIGN_01801 0.0 helD 3.6.4.12 L DNA helicase
OKAIHIGN_01802 7e-175 coaA 2.7.1.33 F Pantothenic acid kinase
OKAIHIGN_01803 2.3e-99 aacA4_1 4.1.1.17 K acetyltransferase
OKAIHIGN_01804 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OKAIHIGN_01805 8.4e-57 bipA 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Leucine-rich repeat (LRR) protein
OKAIHIGN_01806 0.0 rafA 3.2.1.22 G alpha-galactosidase
OKAIHIGN_01807 3.7e-20 K Helix-turn-helix domain
OKAIHIGN_01808 2.2e-96 M NlpC/P60 family
OKAIHIGN_01809 4.4e-75 S Peptidase_C39 like family
OKAIHIGN_01811 1.1e-71 S Iron-sulphur cluster biosynthesis
OKAIHIGN_01812 0.0 pepN 3.4.11.2 E aminopeptidase
OKAIHIGN_01813 1.8e-263 arcD E Arginine ornithine antiporter
OKAIHIGN_01814 1.8e-278 pipD E Dipeptidase
OKAIHIGN_01815 3.2e-93 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
OKAIHIGN_01816 1.8e-69 K Transcriptional regulator
OKAIHIGN_01817 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
OKAIHIGN_01818 2.8e-298 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
OKAIHIGN_01819 3.4e-236 lacY G Oligosaccharide H symporter
OKAIHIGN_01820 1.3e-200 abf G Belongs to the glycosyl hydrolase 43 family
OKAIHIGN_01821 3.8e-146 K transcriptional regulator, ArsR family
OKAIHIGN_01822 8.7e-177 araR K Transcriptional regulator
OKAIHIGN_01823 1.2e-213 melB G symporter
OKAIHIGN_01824 2e-10
OKAIHIGN_01825 1.2e-256 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
OKAIHIGN_01826 2.4e-69 K sequence-specific DNA binding
OKAIHIGN_01827 7.1e-216 G symporter
OKAIHIGN_01828 3.4e-111 yisR K helix_turn_helix, arabinose operon control protein
OKAIHIGN_01829 1.6e-39
OKAIHIGN_01830 6.7e-106 L PFAM Integrase catalytic region
OKAIHIGN_01832 2.6e-60
OKAIHIGN_01833 5.1e-47 S Leucine-rich repeat (LRR) protein
OKAIHIGN_01834 4.6e-93 stp U Belongs to the major facilitator superfamily
OKAIHIGN_01835 7.1e-141 L Integrase core domain
OKAIHIGN_01836 2.7e-11 ps334 S Terminase-like family
OKAIHIGN_01837 7.3e-41 ps333 L Terminase small subunit
OKAIHIGN_01838 1.7e-52 S Pyrimidine dimer DNA glycosylase
OKAIHIGN_01842 1.6e-73 nhaC C Na H antiporter NhaC
OKAIHIGN_01843 2.5e-197 ptcA 2.1.3.3, 2.1.3.6 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OKAIHIGN_01844 3.8e-233 aguD E Amino Acid
OKAIHIGN_01845 1.1e-216 aguA 3.5.3.12 E agmatine deiminase
OKAIHIGN_01846 3.5e-166 arcC 2.7.2.2 E Belongs to the carbamate kinase family
OKAIHIGN_01847 5.2e-217 aguA 3.5.3.12 E agmatine deiminase
OKAIHIGN_01848 5.9e-146 K Helix-turn-helix domain, rpiR family
OKAIHIGN_01849 8.8e-202 EGP Major facilitator Superfamily
OKAIHIGN_01851 1.1e-161 mleR K LysR family
OKAIHIGN_01852 7.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
OKAIHIGN_01853 1.5e-167 mleP S Sodium Bile acid symporter family
OKAIHIGN_01854 3.4e-83 thiW S Thiamine-precursor transporter protein (ThiW)
OKAIHIGN_01855 7.2e-141 K helix_turn _helix lactose operon repressor
OKAIHIGN_01856 1.3e-155 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OKAIHIGN_01857 1.1e-165
OKAIHIGN_01858 1.5e-235 2.7.1.53 G Xylulose kinase
OKAIHIGN_01859 5e-146 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
OKAIHIGN_01860 4.6e-129 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
OKAIHIGN_01861 1.6e-82 G Domain of unknown function (DUF386)
OKAIHIGN_01862 1.1e-212 G Sugar (and other) transporter
OKAIHIGN_01863 6e-63 G Domain of unknown function (DUF386)
OKAIHIGN_01864 4.4e-206 ynfM EGP Major facilitator Superfamily
OKAIHIGN_01865 2e-86 ygfC K Bacterial regulatory proteins, tetR family
OKAIHIGN_01866 2.6e-181 hrtB V ABC transporter permease
OKAIHIGN_01867 1.9e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
OKAIHIGN_01868 4.6e-223 EGP Major facilitator Superfamily
OKAIHIGN_01869 6.8e-98 S Phosphatidylethanolamine-binding protein
OKAIHIGN_01870 3.7e-69 ycgX S Protein of unknown function (DUF1398)
OKAIHIGN_01871 1.1e-118 S GyrI-like small molecule binding domain
OKAIHIGN_01872 6.8e-124 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OKAIHIGN_01873 6.3e-221 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
OKAIHIGN_01874 1.5e-172 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OKAIHIGN_01875 5.8e-118 yeiL K Cyclic nucleotide-monophosphate binding domain
OKAIHIGN_01876 3.6e-179 rihB 3.2.2.1, 3.2.2.8 F Nucleoside
OKAIHIGN_01877 1.5e-208 mccF V LD-carboxypeptidase
OKAIHIGN_01878 3.4e-67 K Transcriptional regulator, HxlR family
OKAIHIGN_01879 9e-12
OKAIHIGN_01880 1.2e-222 C Oxidoreductase
OKAIHIGN_01881 1.9e-15 mdt(A) EGP Major facilitator Superfamily
OKAIHIGN_01882 3.6e-67 2.3.1.209, 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
OKAIHIGN_01883 7e-111 1.6.5.5 C alcohol dehydrogenase
OKAIHIGN_01884 3.9e-54 napB K Transcriptional regulator
OKAIHIGN_01885 1.4e-74 K helix_turn_helix, mercury resistance
OKAIHIGN_01886 4.9e-114
OKAIHIGN_01887 3.2e-135 C Zinc-binding dehydrogenase
OKAIHIGN_01888 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
OKAIHIGN_01889 1.1e-261 G Major Facilitator
OKAIHIGN_01890 5.8e-175 K Transcriptional regulator, LacI family
OKAIHIGN_01891 1.6e-08
OKAIHIGN_01892 1.9e-81
OKAIHIGN_01893 1e-301 E ABC transporter, substratebinding protein
OKAIHIGN_01894 3.7e-249 xylP2 G symporter
OKAIHIGN_01895 5.9e-194 nlhH_1 I alpha/beta hydrolase fold
OKAIHIGN_01896 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
OKAIHIGN_01897 1.5e-18 S integral membrane protein
OKAIHIGN_01898 1.4e-145 G Belongs to the phosphoglycerate mutase family
OKAIHIGN_01899 3e-98 speG J Acetyltransferase (GNAT) domain
OKAIHIGN_01900 2e-49 sugE P Multidrug resistance protein
OKAIHIGN_01901 4.2e-50 ykkC P Small Multidrug Resistance protein
OKAIHIGN_01902 2.7e-205 gldA 1.1.1.6 C dehydrogenase
OKAIHIGN_01903 4.4e-76
OKAIHIGN_01904 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
OKAIHIGN_01905 2.8e-185 tdh 1.1.1.14 C Zinc-binding dehydrogenase
OKAIHIGN_01906 1.9e-141 S Membrane
OKAIHIGN_01907 4.4e-70 4.4.1.5 E Glyoxalase
OKAIHIGN_01909 1.5e-53
OKAIHIGN_01910 1.1e-35 hxlR K HxlR-like helix-turn-helix
OKAIHIGN_01911 1.7e-96 EGP Major facilitator Superfamily
OKAIHIGN_01912 1.2e-222 rodA D Cell cycle protein
OKAIHIGN_01913 3.8e-230 opuAB P Binding-protein-dependent transport system inner membrane component
OKAIHIGN_01914 2.2e-137 P ATPases associated with a variety of cellular activities
OKAIHIGN_01915 7.3e-222 lytR5 K Cell envelope-related transcriptional attenuator domain
OKAIHIGN_01916 1.1e-259 norG_2 K Aminotransferase class I and II
OKAIHIGN_01917 6.9e-139 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H Phosphomethylpyrimidine kinase
OKAIHIGN_01918 4e-84 hmpT S ECF-type riboflavin transporter, S component
OKAIHIGN_01919 1e-99 ywlG S Belongs to the UPF0340 family
OKAIHIGN_01920 1.7e-26 mcbG S Pentapeptide repeats (8 copies)
OKAIHIGN_01921 1.9e-178 K helix_turn _helix lactose operon repressor
OKAIHIGN_01923 2.1e-109 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 GK Winged helix-turn-helix DNA-binding
OKAIHIGN_01924 1.4e-122 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G Phosphomethylpyrimidine kinase
OKAIHIGN_01925 3.7e-112 trpF 5.3.1.24 E belongs to the TrpF family
OKAIHIGN_01926 3.3e-75 S Membrane
OKAIHIGN_01927 4.4e-150 1.1.1.1 C alcohol dehydrogenase
OKAIHIGN_01928 7.1e-188 nupC F Na+ dependent nucleoside transporter C-terminus
OKAIHIGN_01930 1.5e-156 rihA F Inosine-uridine preferring nucleoside hydrolase
OKAIHIGN_01931 5.2e-119 yoaK S Protein of unknown function (DUF1275)
OKAIHIGN_01932 1.3e-304 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
OKAIHIGN_01933 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OKAIHIGN_01934 0.0 yjcE P Sodium proton antiporter
OKAIHIGN_01935 1.9e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OKAIHIGN_01936 3.3e-43
OKAIHIGN_01937 9.1e-167 panE2 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OKAIHIGN_01938 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
OKAIHIGN_01939 7.2e-59 K Helix-turn-helix domain
OKAIHIGN_01940 6.4e-293 ytgP S Polysaccharide biosynthesis protein
OKAIHIGN_01941 3.8e-84 iap CBM50 M NlpC P60 family
OKAIHIGN_01942 1.2e-182 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
OKAIHIGN_01943 7.9e-114
OKAIHIGN_01944 1.3e-102 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
OKAIHIGN_01945 2.7e-203 EGP Major facilitator Superfamily
OKAIHIGN_01946 7.2e-32 arsR K DNA-binding transcription factor activity
OKAIHIGN_01947 1.7e-111 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
OKAIHIGN_01948 1.1e-77 K Winged helix DNA-binding domain
OKAIHIGN_01949 2.7e-49
OKAIHIGN_01951 8.2e-115 rihB 3.2.2.1 F Nucleoside
OKAIHIGN_01952 3e-177 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
OKAIHIGN_01953 5.7e-19 K Acetyltransferase (GNAT) family
OKAIHIGN_01954 7.4e-63 K helix_turn_helix gluconate operon transcriptional repressor
OKAIHIGN_01955 3.6e-177 S DNA/RNA non-specific endonuclease
OKAIHIGN_01957 2e-27
OKAIHIGN_01958 4.9e-26
OKAIHIGN_01959 2.1e-244 frlA E Amino acid permease
OKAIHIGN_01960 1.1e-156 nanK 2.7.1.2 GK ROK family
OKAIHIGN_01961 4.3e-253 brnQ U Component of the transport system for branched-chain amino acids
OKAIHIGN_01962 1.1e-187 S DUF218 domain
OKAIHIGN_01963 1.9e-163
OKAIHIGN_01964 1.2e-73 K Transcriptional regulator
OKAIHIGN_01965 0.0 pepF2 E Oligopeptidase F
OKAIHIGN_01966 4.2e-175 D Alpha beta
OKAIHIGN_01967 7e-127 yoaK S Protein of unknown function (DUF1275)
OKAIHIGN_01968 1.8e-279 rny S Endoribonuclease that initiates mRNA decay
OKAIHIGN_01969 5.2e-248 rarA L recombination factor protein RarA
OKAIHIGN_01970 2.9e-159 akr5f 1.1.1.346 C Aldo keto reductase
OKAIHIGN_01971 1.5e-222 xylR GK ROK family
OKAIHIGN_01972 4.9e-131 K helix_turn_helix, mercury resistance
OKAIHIGN_01973 1.2e-133 XK27_00890 S Domain of unknown function (DUF368)
OKAIHIGN_01977 2.6e-91
OKAIHIGN_01978 2.5e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OKAIHIGN_01979 1.4e-116 ybbL S ABC transporter, ATP-binding protein
OKAIHIGN_01980 1.4e-128 ybbM S Uncharacterised protein family (UPF0014)
OKAIHIGN_01981 7e-150 vdlC S Enoyl-(Acyl carrier protein) reductase
OKAIHIGN_01982 1.8e-139 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OKAIHIGN_01983 7.8e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OKAIHIGN_01984 2.1e-109 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OKAIHIGN_01985 1.4e-286 macB3 V ABC transporter, ATP-binding protein
OKAIHIGN_01987 2e-196 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
OKAIHIGN_01988 2.6e-52
OKAIHIGN_01989 7.6e-59
OKAIHIGN_01990 3.7e-207
OKAIHIGN_01991 9.9e-100 K DNA-templated transcription, initiation
OKAIHIGN_01992 6.7e-27
OKAIHIGN_01993 4.8e-11 S Protein of unknown function (DUF2922)
OKAIHIGN_01994 4.9e-165 K LysR substrate binding domain
OKAIHIGN_01995 1.3e-221 EK Aminotransferase, class I
OKAIHIGN_01996 2.1e-66
OKAIHIGN_01997 4.5e-72
OKAIHIGN_01998 1.6e-276
OKAIHIGN_02000 7.3e-136
OKAIHIGN_02001 8.2e-106
OKAIHIGN_02002 5.5e-35
OKAIHIGN_02003 1.1e-62 K HxlR-like helix-turn-helix
OKAIHIGN_02004 1.6e-39
OKAIHIGN_02005 1.1e-85
OKAIHIGN_02006 6.3e-44
OKAIHIGN_02007 4e-113 GM NmrA-like family
OKAIHIGN_02008 2.3e-153 5.4.2.7 G Metalloenzyme superfamily
OKAIHIGN_02009 5.3e-226 nupG F Nucleoside
OKAIHIGN_02010 2.2e-214 pbuO_1 S Permease family
OKAIHIGN_02011 2.8e-168 rihC 3.2.2.1, 3.2.2.8 F Nucleoside
OKAIHIGN_02012 1.8e-164 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
OKAIHIGN_02013 6.4e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
OKAIHIGN_02014 1.2e-146 noc K Belongs to the ParB family
OKAIHIGN_02015 4.1e-136 soj D Sporulation initiation inhibitor
OKAIHIGN_02016 3.4e-155 spo0J K Belongs to the ParB family
OKAIHIGN_02017 8.5e-33 yyzM S Bacterial protein of unknown function (DUF951)
OKAIHIGN_02018 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OKAIHIGN_02019 3.1e-133 XK27_01040 S Protein of unknown function (DUF1129)
OKAIHIGN_02020 1e-107
OKAIHIGN_02021 2.8e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OKAIHIGN_02022 3.5e-123 K response regulator
OKAIHIGN_02023 7.4e-214 hpk31 2.7.13.3 T Histidine kinase
OKAIHIGN_02024 1.7e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OKAIHIGN_02025 1.9e-176 V domain protein
OKAIHIGN_02026 2.8e-36 S Domain of unknown function (DUF4430)
OKAIHIGN_02027 1.6e-249 gor 1.8.1.7 C Glutathione reductase
OKAIHIGN_02028 3.3e-86 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
OKAIHIGN_02029 7.2e-136 azlC E AzlC protein
OKAIHIGN_02030 1.3e-52 azlD S branched-chain amino acid
OKAIHIGN_02031 3.7e-237 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
OKAIHIGN_02032 3e-122
OKAIHIGN_02033 3.3e-214 xylR GK ROK family
OKAIHIGN_02034 1.8e-169 K AI-2E family transporter
OKAIHIGN_02035 1.9e-262 M domain protein
OKAIHIGN_02036 1.1e-33 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OKAIHIGN_02038 1.2e-28
OKAIHIGN_02039 1.2e-96 yfjF U Sugar (and other) transporter
OKAIHIGN_02040 6.2e-51
OKAIHIGN_02042 1.8e-101 L Transposase and inactivated derivatives, IS30 family
OKAIHIGN_02044 0.0
OKAIHIGN_02045 1.1e-263 araB 2.7.1.16 G carbohydrate kinase FGGY
OKAIHIGN_02046 3.2e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
OKAIHIGN_02047 5e-281 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OKAIHIGN_02048 2.1e-89 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
OKAIHIGN_02051 1.4e-53 S Glycine cleavage H-protein
OKAIHIGN_02052 1.5e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
OKAIHIGN_02053 7.2e-141 yejC S Protein of unknown function (DUF1003)
OKAIHIGN_02054 1.8e-104 3.2.2.20 K acetyltransferase
OKAIHIGN_02055 1.2e-85 nimA S resistance protein
OKAIHIGN_02056 5.1e-90 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
OKAIHIGN_02057 1e-69
OKAIHIGN_02058 4.3e-217 EGP Major facilitator Superfamily
OKAIHIGN_02059 2e-233 pyrP F Permease
OKAIHIGN_02060 2.8e-49 azlD S Branched-chain amino acid transport protein (AzlD)
OKAIHIGN_02061 1.3e-107 azlC E branched-chain amino acid
OKAIHIGN_02062 1e-37 yyaN K MerR HTH family regulatory protein
OKAIHIGN_02063 2.8e-102 S Domain of unknown function (DUF4811)
OKAIHIGN_02064 4.3e-267 lmrB EGP Major facilitator Superfamily
OKAIHIGN_02065 9.6e-74 merR K MerR HTH family regulatory protein
OKAIHIGN_02066 1.3e-102 K Acetyltransferase (GNAT) domain
OKAIHIGN_02067 1.2e-158 czcD P cation diffusion facilitator family transporter
OKAIHIGN_02068 5.3e-121 sirR K iron dependent repressor
OKAIHIGN_02069 2.9e-118 thrE S Putative threonine/serine exporter
OKAIHIGN_02070 1.4e-72 S Threonine/Serine exporter, ThrE
OKAIHIGN_02071 9.4e-121 lssY 3.6.1.27 I phosphatase
OKAIHIGN_02072 1.6e-148 I alpha/beta hydrolase fold
OKAIHIGN_02073 8e-25 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OKAIHIGN_02074 4.8e-274 lysP E amino acid
OKAIHIGN_02075 9.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
OKAIHIGN_02076 5.8e-212 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OKAIHIGN_02085 9.9e-77 ctsR K Belongs to the CtsR family
OKAIHIGN_02086 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
OKAIHIGN_02087 1.9e-104 K Bacterial regulatory proteins, tetR family
OKAIHIGN_02088 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OKAIHIGN_02089 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OKAIHIGN_02090 8.5e-111 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
OKAIHIGN_02091 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OKAIHIGN_02092 3.2e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OKAIHIGN_02093 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OKAIHIGN_02094 2.4e-229 mepA V MATE efflux family protein
OKAIHIGN_02095 8.9e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
OKAIHIGN_02096 6.1e-117 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OKAIHIGN_02097 3.2e-107 rplD J Forms part of the polypeptide exit tunnel
OKAIHIGN_02098 2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OKAIHIGN_02099 7.9e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OKAIHIGN_02100 1.8e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OKAIHIGN_02101 2.4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OKAIHIGN_02102 5.1e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OKAIHIGN_02103 7.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OKAIHIGN_02104 4.8e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OKAIHIGN_02105 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OKAIHIGN_02106 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OKAIHIGN_02107 1.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OKAIHIGN_02108 2.1e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OKAIHIGN_02109 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OKAIHIGN_02110 3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OKAIHIGN_02111 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OKAIHIGN_02112 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OKAIHIGN_02113 3.8e-24 rpmD J Ribosomal protein L30
OKAIHIGN_02114 4.1e-69 rplO J Binds to the 23S rRNA
OKAIHIGN_02115 1.2e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OKAIHIGN_02116 3.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OKAIHIGN_02117 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OKAIHIGN_02118 1.3e-60 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OKAIHIGN_02119 7.5e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OKAIHIGN_02120 9.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OKAIHIGN_02121 7.4e-62 rplQ J Ribosomal protein L17
OKAIHIGN_02122 9.9e-152 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OKAIHIGN_02123 2.4e-161 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OKAIHIGN_02124 1e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OKAIHIGN_02125 2.5e-152 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OKAIHIGN_02126 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OKAIHIGN_02127 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OKAIHIGN_02128 3e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
OKAIHIGN_02129 1.4e-240 ktrB P Potassium uptake protein
OKAIHIGN_02130 1.8e-116 ktrA P domain protein
OKAIHIGN_02131 3e-198 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OKAIHIGN_02132 3.9e-102 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
OKAIHIGN_02133 2.4e-220 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
OKAIHIGN_02134 2.2e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OKAIHIGN_02135 3.9e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
OKAIHIGN_02136 1.2e-253 yfnA E Amino Acid
OKAIHIGN_02137 1.1e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
OKAIHIGN_02138 8e-159 brpA K Cell envelope-like function transcriptional attenuator common domain protein
OKAIHIGN_02139 3.5e-90 epsB M biosynthesis protein
OKAIHIGN_02140 8.2e-129 ywqD 2.7.10.1 D Capsular exopolysaccharide family
OKAIHIGN_02141 6.8e-139 ywqE 3.1.3.48 GM PHP domain protein
OKAIHIGN_02142 5.5e-84 rfbP M Bacterial sugar transferase
OKAIHIGN_02143 1.6e-79 tagA 2.4.1.187 GT26 M Belongs to the glycosyltransferase 26 family
OKAIHIGN_02144 6.3e-82 GT4 M Glycosyltransferase Family 4
OKAIHIGN_02145 4.5e-59 M Glycosyl transferases group 1
OKAIHIGN_02146 2.9e-51 M -O-antigen
OKAIHIGN_02147 1.9e-83 cps2J S Polysaccharide biosynthesis protein
OKAIHIGN_02148 5.1e-67 wcmJ S SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
OKAIHIGN_02149 1.8e-153 brpA K Cell envelope-like function transcriptional attenuator common domain protein
OKAIHIGN_02150 9.4e-166 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OKAIHIGN_02151 3.9e-147 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OKAIHIGN_02152 9.6e-180 pdxB EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
OKAIHIGN_02153 2.7e-282 cydA 1.10.3.14 C ubiquinol oxidase
OKAIHIGN_02154 1.1e-173 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
OKAIHIGN_02155 9.1e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
OKAIHIGN_02156 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OKAIHIGN_02157 3.5e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OKAIHIGN_02158 6.7e-154 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
OKAIHIGN_02159 5.1e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OKAIHIGN_02160 7.2e-214 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OKAIHIGN_02161 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OKAIHIGN_02162 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OKAIHIGN_02163 1.1e-193 camS S sex pheromone
OKAIHIGN_02164 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OKAIHIGN_02165 1.9e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OKAIHIGN_02166 6.5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OKAIHIGN_02167 9.4e-189 yegS 2.7.1.107 G Lipid kinase
OKAIHIGN_02168 6.3e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OKAIHIGN_02169 3.3e-42 eutP E Ethanolamine utilisation - propanediol utilisation
OKAIHIGN_02170 9.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
OKAIHIGN_02171 4.8e-207 K helix_turn_helix, arabinose operon control protein
OKAIHIGN_02172 5.2e-41 pduA_4 CQ BMC
OKAIHIGN_02173 1.2e-129 pduB E BMC
OKAIHIGN_02174 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
OKAIHIGN_02175 1e-128 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
OKAIHIGN_02176 3e-90 pduE 4.2.1.28 Q Dehydratase small subunit
OKAIHIGN_02177 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
OKAIHIGN_02178 1.1e-56 pduH S Dehydratase medium subunit
OKAIHIGN_02179 9.7e-83 pduK CQ BMC
OKAIHIGN_02180 4.9e-42 pduA_4 CQ BMC
OKAIHIGN_02181 6.1e-114 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
OKAIHIGN_02182 3e-90 S Putative propanediol utilisation
OKAIHIGN_02183 6e-42 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
OKAIHIGN_02184 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
OKAIHIGN_02185 1.4e-81 pduO S Haem-degrading
OKAIHIGN_02186 1.6e-266 pduP 1.2.1.87 C Aldehyde dehydrogenase family
OKAIHIGN_02187 6.2e-210 pduQ C Iron-containing alcohol dehydrogenase
OKAIHIGN_02188 7e-220 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OKAIHIGN_02189 7.8e-55 pduU E BMC
OKAIHIGN_02190 3.5e-194 C Oxidoreductase
OKAIHIGN_02191 1.1e-144 3.1.3.48 T Pfam:Y_phosphatase3C
OKAIHIGN_02192 7.8e-58 K Helix-turn-helix XRE-family like proteins
OKAIHIGN_02193 5.1e-37 cro K Helix-turn-helix XRE-family like proteins
OKAIHIGN_02194 1.3e-120 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OKAIHIGN_02195 1.1e-233 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OKAIHIGN_02196 1.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OKAIHIGN_02197 1.2e-172 deoR K sugar-binding domain protein
OKAIHIGN_02198 8.7e-240 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
OKAIHIGN_02199 9.4e-294 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
OKAIHIGN_02200 2.5e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OKAIHIGN_02201 4.1e-248 fucP G Major Facilitator Superfamily
OKAIHIGN_02202 1.8e-232 potE E amino acid
OKAIHIGN_02203 4.3e-213 gntP EG Gluconate
OKAIHIGN_02204 2.3e-303 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
OKAIHIGN_02205 3.2e-150 gntR K rpiR family
OKAIHIGN_02206 1.6e-145 lys M Glycosyl hydrolases family 25
OKAIHIGN_02207 5.7e-64 S Domain of unknown function (DUF4828)
OKAIHIGN_02208 7.3e-186 mocA S Oxidoreductase
OKAIHIGN_02209 7.6e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
OKAIHIGN_02211 5.6e-77 T Universal stress protein family
OKAIHIGN_02212 4.1e-232 gntP EG Gluconate
OKAIHIGN_02213 4.2e-159 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
OKAIHIGN_02214 6.7e-212 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OKAIHIGN_02215 2.1e-157 S Nuclease-related domain
OKAIHIGN_02216 9e-159 yihY S Belongs to the UPF0761 family
OKAIHIGN_02217 1e-78 fld C Flavodoxin
OKAIHIGN_02218 1.2e-143 recX 2.4.1.337 GT4 S Regulatory protein RecX
OKAIHIGN_02219 2.3e-215 pbpX2 V Beta-lactamase
OKAIHIGN_02220 5.6e-39 S Bacteriocin-protection, YdeI or OmpD-Associated
OKAIHIGN_02221 4.4e-108 ygaC J Belongs to the UPF0374 family
OKAIHIGN_02222 1.4e-180 yueF S AI-2E family transporter
OKAIHIGN_02223 2.6e-76 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
OKAIHIGN_02224 2.9e-154
OKAIHIGN_02225 0.0 2.7.8.12 M glycerophosphotransferase
OKAIHIGN_02226 4.3e-87
OKAIHIGN_02227 1.3e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OKAIHIGN_02228 4.5e-270 XK27_00720 S Leucine-rich repeat (LRR) protein
OKAIHIGN_02229 1.8e-256 nox 1.6.3.4 C NADH oxidase
OKAIHIGN_02230 6.6e-281 pipD E Dipeptidase
OKAIHIGN_02231 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
OKAIHIGN_02232 1.7e-204 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
OKAIHIGN_02233 0.0 clpE O Belongs to the ClpA ClpB family
OKAIHIGN_02234 3.9e-30
OKAIHIGN_02235 7.2e-40 ptsH G phosphocarrier protein HPR
OKAIHIGN_02236 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OKAIHIGN_02237 2.7e-224 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
OKAIHIGN_02238 1.7e-193 cpoA GT4 M Glycosyltransferase, group 1 family protein
OKAIHIGN_02239 4.1e-184 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OKAIHIGN_02240 4.3e-36 ykuJ S Protein of unknown function (DUF1797)
OKAIHIGN_02241 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
OKAIHIGN_02242 7.1e-10
OKAIHIGN_02244 2.2e-99 K Bacterial regulatory proteins, tetR family
OKAIHIGN_02245 3.7e-301 E ABC transporter, substratebinding protein
OKAIHIGN_02246 9.1e-228 Q Imidazolonepropionase and related amidohydrolases
OKAIHIGN_02247 9.5e-141
OKAIHIGN_02248 4.2e-300 E ABC transporter, substratebinding protein
OKAIHIGN_02249 9.8e-230 Q Imidazolonepropionase and related amidohydrolases
OKAIHIGN_02250 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OKAIHIGN_02251 3e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OKAIHIGN_02252 1.9e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
OKAIHIGN_02253 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OKAIHIGN_02254 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OKAIHIGN_02255 1.7e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OKAIHIGN_02256 2e-35 yaaA S S4 domain protein YaaA
OKAIHIGN_02257 8.5e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OKAIHIGN_02258 1.7e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OKAIHIGN_02259 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
OKAIHIGN_02260 3.2e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OKAIHIGN_02261 1e-145 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OKAIHIGN_02262 5.9e-111 jag S R3H domain protein
OKAIHIGN_02263 3.2e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OKAIHIGN_02264 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OKAIHIGN_02265 4.4e-54
OKAIHIGN_02266 3e-37
OKAIHIGN_02267 5.4e-124 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
OKAIHIGN_02268 1.4e-35
OKAIHIGN_02269 9.3e-245 brnQ U Component of the transport system for branched-chain amino acids
OKAIHIGN_02270 1.8e-113 ywnB S NAD(P)H-binding
OKAIHIGN_02271 1.4e-98 J Acetyltransferase (GNAT) domain
OKAIHIGN_02272 1.2e-91 ykhA 3.1.2.20 I Thioesterase superfamily
OKAIHIGN_02273 1.6e-224 S module of peptide synthetase
OKAIHIGN_02274 4.5e-217 tcaB EGP Major facilitator Superfamily
OKAIHIGN_02275 4.2e-109 lepB 3.4.21.89 U Belongs to the peptidase S26 family
OKAIHIGN_02276 8.9e-78 K helix_turn_helix multiple antibiotic resistance protein
OKAIHIGN_02277 8.6e-251 pepC 3.4.22.40 E aminopeptidase
OKAIHIGN_02278 2.6e-112 L haloacid dehalogenase-like hydrolase
OKAIHIGN_02280 7.2e-25
OKAIHIGN_02281 1.8e-50
OKAIHIGN_02283 2.8e-85 S regulation of response to stimulus
OKAIHIGN_02286 4.5e-89
OKAIHIGN_02287 4.5e-149 F DNA/RNA non-specific endonuclease
OKAIHIGN_02288 5.2e-22
OKAIHIGN_02289 9.7e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OKAIHIGN_02290 2.9e-141 rhaS2 K Transcriptional regulator, AraC family
OKAIHIGN_02291 6.3e-279 xynT G MFS/sugar transport protein
OKAIHIGN_02292 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OKAIHIGN_02293 0.0 S Predicted membrane protein (DUF2207)
OKAIHIGN_02295 1.2e-13
OKAIHIGN_02296 7e-29 M hydrolase, family 25
OKAIHIGN_02297 7.5e-159 S Bacterial SH3 domain
OKAIHIGN_02298 4.4e-29
OKAIHIGN_02299 2.9e-44 M hydrolase, family 25
OKAIHIGN_02300 1.8e-10
OKAIHIGN_02303 1.2e-86 ccl S QueT transporter
OKAIHIGN_02304 0.0 S Bacterial membrane protein YfhO
OKAIHIGN_02305 1.4e-167 2.5.1.74 H UbiA prenyltransferase family
OKAIHIGN_02306 7e-120 drrB U ABC-2 type transporter
OKAIHIGN_02307 1.5e-161 drrA V ABC transporter
OKAIHIGN_02308 5e-93 K helix_turn_helix multiple antibiotic resistance protein
OKAIHIGN_02309 5.9e-228 pbuG S permease
OKAIHIGN_02310 1.1e-181 iolS C Aldo keto reductase
OKAIHIGN_02311 4.6e-103 GM NAD(P)H-binding
OKAIHIGN_02312 1.3e-58
OKAIHIGN_02313 4e-184 xynD 3.5.1.104 G polysaccharide deacetylase
OKAIHIGN_02314 2.7e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
OKAIHIGN_02315 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
OKAIHIGN_02316 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OKAIHIGN_02317 1.5e-166
OKAIHIGN_02318 4.2e-141 K Helix-turn-helix domain
OKAIHIGN_02319 2.9e-190 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
OKAIHIGN_02320 1.5e-94 qorB 1.6.5.2 GM NmrA-like family
OKAIHIGN_02321 2.4e-69 K Transcriptional regulator
OKAIHIGN_02322 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
OKAIHIGN_02323 3.4e-172 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
OKAIHIGN_02324 5e-134 1.1.1.219 GM Male sterility protein
OKAIHIGN_02325 4.9e-50 K Bacterial regulatory proteins, tetR family
OKAIHIGN_02326 4e-28 K helix_turn_helix, mercury resistance
OKAIHIGN_02327 7.6e-62 yliE T EAL domain
OKAIHIGN_02328 2.1e-101 S Alpha beta hydrolase
OKAIHIGN_02329 8.1e-77 GM NmrA-like family
OKAIHIGN_02330 2.9e-57 adhR K MerR, DNA binding
OKAIHIGN_02331 4.9e-47 C Flavodoxin
OKAIHIGN_02332 5.8e-178 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
OKAIHIGN_02334 6.6e-140 S Alpha/beta hydrolase family
OKAIHIGN_02335 9.2e-58 K MarR family
OKAIHIGN_02337 2.6e-87 K AraC-like ligand binding domain
OKAIHIGN_02338 7.4e-237 xynP G MFS/sugar transport protein
OKAIHIGN_02339 1.8e-274 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OKAIHIGN_02340 2e-37 T Cyclic nucleotide-binding protein
OKAIHIGN_02341 4.6e-63 1.6.5.2 S NADPH-dependent FMN reductase
OKAIHIGN_02342 5.4e-134 lmrB EGP Major facilitator Superfamily
OKAIHIGN_02343 1.4e-54 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OKAIHIGN_02344 1.6e-42 K helix_turn_helix multiple antibiotic resistance protein
OKAIHIGN_02345 1.1e-158 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M MucBP domain
OKAIHIGN_02346 1.3e-46 S NADPH-dependent FMN reductase
OKAIHIGN_02347 5.2e-305 M Mycoplasma protein of unknown function, DUF285
OKAIHIGN_02348 4e-72
OKAIHIGN_02349 2e-26 K Transcriptional
OKAIHIGN_02350 2.5e-222 LO Uncharacterized conserved protein (DUF2075)
OKAIHIGN_02351 1.9e-115 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
OKAIHIGN_02352 2.4e-121
OKAIHIGN_02353 9.3e-107 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
OKAIHIGN_02354 1.2e-156 C Aldo keto reductase
OKAIHIGN_02355 1.3e-202 pmrB EGP Major facilitator Superfamily
OKAIHIGN_02356 1.9e-71 S COG NOG18757 non supervised orthologous group
OKAIHIGN_02357 5.3e-135 K helix_turn_helix, arabinose operon control protein
OKAIHIGN_02358 0.0 3.2.1.55 GH51 G Right handed beta helix region
OKAIHIGN_02359 4.9e-208 G Major Facilitator
OKAIHIGN_02360 1.2e-23
OKAIHIGN_02361 2.4e-231 EK Aminotransferase, class I
OKAIHIGN_02362 0.0 tetP J elongation factor G
OKAIHIGN_02363 2.5e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
OKAIHIGN_02364 3e-13 yhaZ L DNA alkylation repair enzyme
OKAIHIGN_02367 7.6e-37 yhaZ L DNA alkylation repair enzyme
OKAIHIGN_02368 1.2e-118 yihL K UTRA
OKAIHIGN_02369 1.2e-185 yegU O ADP-ribosylglycohydrolase
OKAIHIGN_02370 1.4e-251 F Belongs to the purine-cytosine permease (2.A.39) family
OKAIHIGN_02371 2.4e-161 G Belongs to the carbohydrate kinase PfkB family
OKAIHIGN_02372 5e-170 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
OKAIHIGN_02373 4.5e-129 S Protein of unknown function
OKAIHIGN_02374 8.3e-216 naiP EGP Major facilitator Superfamily
OKAIHIGN_02375 1.9e-119 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OKAIHIGN_02376 4.6e-109 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OKAIHIGN_02377 7.1e-138 S Belongs to the UPF0246 family
OKAIHIGN_02378 5.3e-305 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
OKAIHIGN_02379 1.7e-154 K Transcriptional regulator
OKAIHIGN_02380 3.6e-14 yjdF S Protein of unknown function (DUF2992)
OKAIHIGN_02381 6.4e-14 S Transglycosylase associated protein
OKAIHIGN_02382 3.6e-39
OKAIHIGN_02383 5.4e-302 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
OKAIHIGN_02384 3.1e-156 EG EamA-like transporter family
OKAIHIGN_02385 1.9e-26
OKAIHIGN_02386 1.4e-207 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
OKAIHIGN_02389 1.3e-38
OKAIHIGN_02390 3.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OKAIHIGN_02391 0.0 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
OKAIHIGN_02392 6.8e-262 E Amino acid permease
OKAIHIGN_02393 3.2e-155 nhaC C Na H antiporter NhaC
OKAIHIGN_02394 1.9e-200 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OKAIHIGN_02395 1.1e-25 copZ P Heavy-metal-associated domain
OKAIHIGN_02396 2.8e-94 dps P Belongs to the Dps family
OKAIHIGN_02397 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
OKAIHIGN_02398 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
OKAIHIGN_02399 1.3e-252 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OKAIHIGN_02400 9.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OKAIHIGN_02401 1.7e-12
OKAIHIGN_02402 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OKAIHIGN_02403 4.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OKAIHIGN_02404 1.5e-132 ybbR S YbbR-like protein
OKAIHIGN_02405 1e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OKAIHIGN_02406 1.7e-122 S Protein of unknown function (DUF1361)
OKAIHIGN_02407 0.0 yjcE P Sodium proton antiporter
OKAIHIGN_02408 5e-165 murB 1.3.1.98 M Cell wall formation
OKAIHIGN_02409 1.3e-150 xth 3.1.11.2 L exodeoxyribonuclease III
OKAIHIGN_02410 6e-102 dnaQ 2.7.7.7 L DNA polymerase III
OKAIHIGN_02411 2.8e-193 C Aldo keto reductase family protein
OKAIHIGN_02412 1.4e-87 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
OKAIHIGN_02413 1.9e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
OKAIHIGN_02414 1.6e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
OKAIHIGN_02415 3e-141 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OKAIHIGN_02416 4.9e-102 yxjI
OKAIHIGN_02417 7.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
OKAIHIGN_02418 2.3e-81 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
OKAIHIGN_02419 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OKAIHIGN_02420 8.1e-137 est 3.1.1.1 S Serine aminopeptidase, S33
OKAIHIGN_02421 4.9e-32 secG U Preprotein translocase
OKAIHIGN_02422 7.6e-283 clcA P chloride
OKAIHIGN_02424 8e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OKAIHIGN_02425 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OKAIHIGN_02426 4.3e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OKAIHIGN_02427 9e-192 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OKAIHIGN_02428 1e-182 cggR K Putative sugar-binding domain
OKAIHIGN_02430 1.4e-107 S ECF transporter, substrate-specific component
OKAIHIGN_02432 1.3e-125 liaI S membrane
OKAIHIGN_02433 2.8e-73 XK27_02470 K LytTr DNA-binding domain
OKAIHIGN_02434 1.7e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OKAIHIGN_02435 9.9e-169 whiA K May be required for sporulation
OKAIHIGN_02436 3.4e-191 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OKAIHIGN_02437 4.8e-165 rapZ S Displays ATPase and GTPase activities
OKAIHIGN_02438 2.4e-90 S Short repeat of unknown function (DUF308)
OKAIHIGN_02439 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OKAIHIGN_02440 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OKAIHIGN_02441 4.5e-94 K acetyltransferase
OKAIHIGN_02442 3.3e-115 yfbR S HD containing hydrolase-like enzyme
OKAIHIGN_02444 4.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OKAIHIGN_02445 2.8e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OKAIHIGN_02446 1.5e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OKAIHIGN_02447 2.1e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OKAIHIGN_02448 9.5e-172 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OKAIHIGN_02449 5.5e-30 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
OKAIHIGN_02450 1.7e-54 pspC KT PspC domain protein
OKAIHIGN_02451 1.4e-119 phoU P Plays a role in the regulation of phosphate uptake
OKAIHIGN_02452 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OKAIHIGN_02453 1.8e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OKAIHIGN_02454 7.7e-155 pstA P Phosphate transport system permease protein PstA
OKAIHIGN_02455 2e-158 pstC P probably responsible for the translocation of the substrate across the membrane
OKAIHIGN_02456 2.1e-160 pstS P Phosphate
OKAIHIGN_02457 3.1e-248 phoR 2.7.13.3 T Histidine kinase
OKAIHIGN_02458 7.6e-129 K response regulator
OKAIHIGN_02459 4.3e-222 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
OKAIHIGN_02460 5.6e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OKAIHIGN_02461 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OKAIHIGN_02462 7.9e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OKAIHIGN_02463 2e-123 comFC S Competence protein
OKAIHIGN_02464 8.2e-254 comFA L Helicase C-terminal domain protein
OKAIHIGN_02465 1.3e-114 yvyE 3.4.13.9 S YigZ family
OKAIHIGN_02466 3.6e-178 tagO 2.7.8.33, 2.7.8.35 M transferase
OKAIHIGN_02467 1.6e-60 lrgA S LrgA family
OKAIHIGN_02468 3.7e-140 lrgB M LrgB-like family
OKAIHIGN_02469 0.0 ydaO E amino acid
OKAIHIGN_02470 6.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OKAIHIGN_02471 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OKAIHIGN_02472 6.9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OKAIHIGN_02473 0.0 uup S ABC transporter, ATP-binding protein
OKAIHIGN_02474 7.5e-46 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
OKAIHIGN_02475 5.7e-214 yeaN P Transporter, major facilitator family protein
OKAIHIGN_02476 1.4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OKAIHIGN_02477 2.2e-108 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
OKAIHIGN_02478 3.2e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
OKAIHIGN_02479 4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
OKAIHIGN_02480 2.6e-163 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OKAIHIGN_02481 1.7e-38 yabA L Involved in initiation control of chromosome replication
OKAIHIGN_02482 6.7e-179 holB 2.7.7.7 L DNA polymerase III
OKAIHIGN_02483 2.2e-54 yaaQ S Cyclic-di-AMP receptor
OKAIHIGN_02484 5.1e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OKAIHIGN_02485 1.3e-38 yaaL S Protein of unknown function (DUF2508)
OKAIHIGN_02486 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OKAIHIGN_02487 1.6e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OKAIHIGN_02488 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OKAIHIGN_02489 6e-89 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OKAIHIGN_02490 5.2e-110 rsmC 2.1.1.172 J Methyltransferase
OKAIHIGN_02491 4.9e-37 nrdH O Glutaredoxin
OKAIHIGN_02492 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKAIHIGN_02493 8.5e-195 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OKAIHIGN_02494 2.6e-166 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
OKAIHIGN_02495 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
OKAIHIGN_02496 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OKAIHIGN_02497 4e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OKAIHIGN_02498 7.7e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OKAIHIGN_02499 1.2e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OKAIHIGN_02500 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OKAIHIGN_02501 1.1e-98 nusG K Participates in transcription elongation, termination and antitermination
OKAIHIGN_02502 4.3e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OKAIHIGN_02503 2.8e-97 sigH K Sigma-70 region 2
OKAIHIGN_02504 6.3e-91 yacP S YacP-like NYN domain
OKAIHIGN_02505 5.7e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OKAIHIGN_02506 7.8e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OKAIHIGN_02507 1.7e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OKAIHIGN_02508 3.1e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OKAIHIGN_02509 4.9e-213 yacL S domain protein
OKAIHIGN_02510 4.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OKAIHIGN_02511 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
OKAIHIGN_02512 7.8e-55
OKAIHIGN_02513 5.3e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OKAIHIGN_02515 5e-259 pepC 3.4.22.40 E Peptidase C1-like family
OKAIHIGN_02516 2.3e-226 V Beta-lactamase
OKAIHIGN_02517 4.2e-121 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OKAIHIGN_02518 3.4e-170 EG EamA-like transporter family
OKAIHIGN_02519 6.1e-166 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
OKAIHIGN_02520 4.6e-205 brpA K Cell envelope-like function transcriptional attenuator common domain protein
OKAIHIGN_02521 5.7e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
OKAIHIGN_02522 3.8e-208 XK27_06930 V domain protein
OKAIHIGN_02523 2.7e-100 K Bacterial regulatory proteins, tetR family
OKAIHIGN_02524 1.8e-116 yliE T EAL domain
OKAIHIGN_02525 2e-163 2.7.7.65 T diguanylate cyclase
OKAIHIGN_02526 5.5e-176 K AI-2E family transporter
OKAIHIGN_02527 1.8e-153 manN G system, mannose fructose sorbose family IID component
OKAIHIGN_02528 1.6e-116 manM G PTS system
OKAIHIGN_02529 1.4e-60 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
OKAIHIGN_02530 4.3e-55 manL 2.7.1.191 G PTS system fructose IIA component
OKAIHIGN_02531 5.8e-109 gph 3.1.3.18 S HAD hydrolase, family IA, variant
OKAIHIGN_02532 2.6e-245 dinF V MatE
OKAIHIGN_02533 6.6e-75 K MarR family
OKAIHIGN_02534 1.6e-100 S Psort location CytoplasmicMembrane, score
OKAIHIGN_02535 1.4e-61 yobS K transcriptional regulator
OKAIHIGN_02536 1.9e-123 S Alpha/beta hydrolase family
OKAIHIGN_02537 3.6e-150 4.1.1.52 S Amidohydrolase
OKAIHIGN_02539 3.7e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OKAIHIGN_02540 4e-89 ydcK S Belongs to the SprT family
OKAIHIGN_02541 0.0 yhgF K Tex-like protein N-terminal domain protein
OKAIHIGN_02542 6.8e-72
OKAIHIGN_02543 6.7e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OKAIHIGN_02544 4.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OKAIHIGN_02545 1.2e-140 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OKAIHIGN_02546 3.1e-92 MA20_25245 K FR47-like protein
OKAIHIGN_02547 1.9e-124 gntR1 K UbiC transcription regulator-associated domain protein
OKAIHIGN_02548 7e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OKAIHIGN_02549 4.7e-135 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OKAIHIGN_02552 1.1e-149 yjjH S Calcineurin-like phosphoesterase
OKAIHIGN_02553 1.3e-298 dtpT U amino acid peptide transporter
OKAIHIGN_02554 1.4e-50 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
OKAIHIGN_02557 1.9e-141 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OKAIHIGN_02558 4.5e-85
OKAIHIGN_02559 1.8e-239 codA 3.5.4.1 F cytosine deaminase
OKAIHIGN_02560 1.4e-47
OKAIHIGN_02561 3.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OKAIHIGN_02562 5.2e-18
OKAIHIGN_02563 1.2e-123 yrkL S Flavodoxin-like fold
OKAIHIGN_02565 6.2e-30
OKAIHIGN_02567 5.1e-37 S Cytochrome B5
OKAIHIGN_02568 2.1e-31 cspC K Cold shock protein
OKAIHIGN_02569 1.7e-108 XK27_00220 S Dienelactone hydrolase family
OKAIHIGN_02570 4.4e-52
OKAIHIGN_02571 8.8e-220 mutY L A G-specific adenine glycosylase
OKAIHIGN_02572 1.9e-303 E Bacterial extracellular solute-binding proteins, family 5 Middle
OKAIHIGN_02573 0.0 pelX M domain, Protein
OKAIHIGN_02574 4.8e-51
OKAIHIGN_02575 5.1e-190 6.3.1.20 H Lipoate-protein ligase
OKAIHIGN_02576 6.3e-66 gcvH E glycine cleavage
OKAIHIGN_02577 3.3e-183 tas C Aldo/keto reductase family
OKAIHIGN_02578 2.1e-32
OKAIHIGN_02579 1.6e-177 EG EamA-like transporter family
OKAIHIGN_02580 1.1e-113 metI P ABC transporter permease
OKAIHIGN_02581 6.5e-193 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OKAIHIGN_02582 1e-145 P Belongs to the nlpA lipoprotein family
OKAIHIGN_02583 5.9e-97 tag 3.2.2.20 L glycosylase
OKAIHIGN_02584 0.0 E ABC transporter, substratebinding protein
OKAIHIGN_02586 0.0 3.2.1.21 GH3 G hydrolase, family 3
OKAIHIGN_02587 1.1e-189 pva1 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OKAIHIGN_02588 9.3e-304 sbcC L Putative exonuclease SbcCD, C subunit
OKAIHIGN_02589 7.7e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OKAIHIGN_02590 6.7e-104 tag 3.2.2.20 L glycosylase
OKAIHIGN_02591 3.5e-109 S Zinc-dependent metalloprotease
OKAIHIGN_02592 2.9e-168 XK27_00880 3.5.1.28 M hydrolase, family 25
OKAIHIGN_02593 1.5e-203 G Glycosyl hydrolases family 8
OKAIHIGN_02594 7.3e-55 yphJ 4.1.1.44 S decarboxylase
OKAIHIGN_02595 3.6e-78 yphH S Cupin domain
OKAIHIGN_02596 2.9e-75 K helix_turn_helix, mercury resistance
OKAIHIGN_02597 4.5e-100 yobS K Bacterial regulatory proteins, tetR family
OKAIHIGN_02598 6.9e-10 K MarR family
OKAIHIGN_02599 7.8e-230
OKAIHIGN_02600 6e-157 dkgB S reductase
OKAIHIGN_02601 2.1e-200 EGP Major facilitator Superfamily
OKAIHIGN_02602 2.2e-152 EGP Major facilitator Superfamily
OKAIHIGN_02603 2.1e-33 EGP Major facilitator Superfamily
OKAIHIGN_02604 2.8e-134 C Oxidoreductase
OKAIHIGN_02605 1.9e-40 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
OKAIHIGN_02606 3.7e-59 K helix_turn_helix, arabinose operon control protein
OKAIHIGN_02607 7.5e-60 S Domain of unknown function (DUF4430)
OKAIHIGN_02608 3.8e-177 U FFAT motif binding
OKAIHIGN_02609 4e-113 S ECF-type riboflavin transporter, S component
OKAIHIGN_02610 4e-306 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
OKAIHIGN_02611 5.2e-159 P ABC-type cobalt transport system permease component CbiQ and related transporters
OKAIHIGN_02612 1.8e-69
OKAIHIGN_02613 2.1e-97 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
OKAIHIGN_02614 1.1e-283 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
OKAIHIGN_02615 6.1e-160 K LysR substrate binding domain
OKAIHIGN_02616 4.6e-70 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
OKAIHIGN_02617 0.0 epsA I PAP2 superfamily
OKAIHIGN_02618 6e-55 S Domain of unknown function (DU1801)
OKAIHIGN_02619 3.2e-110 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
OKAIHIGN_02620 1.4e-107 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OKAIHIGN_02621 5.8e-261 lmrA 3.6.3.44 V ABC transporter
OKAIHIGN_02622 2.4e-40 lmrA 3.6.3.44 V ABC transporter
OKAIHIGN_02623 3.3e-92 rmaB K Transcriptional regulator, MarR family
OKAIHIGN_02624 6.3e-123 S membrane transporter protein
OKAIHIGN_02625 5.2e-139 3.1.3.48 T Tyrosine phosphatase family
OKAIHIGN_02626 2.4e-120
OKAIHIGN_02627 4.3e-124 skfE V ATPases associated with a variety of cellular activities
OKAIHIGN_02628 1.9e-62 yvoA_1 K Transcriptional regulator, GntR family
OKAIHIGN_02629 2.3e-173 3.5.2.6 V Beta-lactamase enzyme family
OKAIHIGN_02630 6.9e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OKAIHIGN_02631 6.8e-128 S haloacid dehalogenase-like hydrolase
OKAIHIGN_02632 2.2e-202 bcr1 EGP Major facilitator Superfamily
OKAIHIGN_02633 6.6e-145 S Sucrose-6F-phosphate phosphohydrolase
OKAIHIGN_02634 4.7e-156 map 3.4.11.18 E Methionine Aminopeptidase
OKAIHIGN_02635 3.3e-100
OKAIHIGN_02636 2.2e-131 ydfG S KR domain
OKAIHIGN_02637 3e-65 hxlR K HxlR-like helix-turn-helix
OKAIHIGN_02638 7.4e-60 asp2 S Asp23 family, cell envelope-related function
OKAIHIGN_02639 3.6e-70 asp S Asp23 family, cell envelope-related function
OKAIHIGN_02640 5.9e-25
OKAIHIGN_02641 5.3e-90
OKAIHIGN_02642 4.4e-18 S Transglycosylase associated protein
OKAIHIGN_02643 2.1e-155
OKAIHIGN_02644 1.9e-270 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
OKAIHIGN_02645 6.8e-183 chaT1 U Major Facilitator Superfamily
OKAIHIGN_02646 6.3e-94 laaE K Transcriptional regulator PadR-like family
OKAIHIGN_02647 1e-66 lysM M LysM domain
OKAIHIGN_02648 8.2e-131 XK27_07210 6.1.1.6 S B3 4 domain
OKAIHIGN_02649 6.6e-122 iprA K Cyclic nucleotide-monophosphate binding domain
OKAIHIGN_02650 6.2e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
OKAIHIGN_02651 6.8e-217 arcT 2.6.1.1 E Aminotransferase
OKAIHIGN_02652 3.2e-256 arcD E Arginine ornithine antiporter
OKAIHIGN_02653 3.3e-197 argF 2.1.3.3, 2.1.3.6, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OKAIHIGN_02654 7.7e-238 arcA 3.5.3.6 E Arginine
OKAIHIGN_02655 5.7e-278 S C4-dicarboxylate anaerobic carrier
OKAIHIGN_02656 9.1e-221 2.1.1.80, 2.7.13.3, 3.1.1.61 T histidine kinase DNA gyrase B
OKAIHIGN_02657 6.5e-148 KT YcbB domain
OKAIHIGN_02658 1.2e-280 arcD S C4-dicarboxylate anaerobic carrier
OKAIHIGN_02659 1.3e-259 ytjP 3.5.1.18 E Dipeptidase
OKAIHIGN_02661 2.5e-209 ykiI
OKAIHIGN_02662 1.1e-104 thiJ-2 3.5.1.124 S DJ-1/PfpI family
OKAIHIGN_02663 1.5e-190 yjcE P Sodium proton antiporter
OKAIHIGN_02664 3.2e-159 3.1.3.48 T Tyrosine phosphatase family
OKAIHIGN_02665 2.1e-59 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
OKAIHIGN_02666 1.5e-221 EGP Major facilitator Superfamily
OKAIHIGN_02667 1.2e-68 yobT S PFAM Metallo-beta-lactamase superfamily
OKAIHIGN_02668 4.8e-16 K helix_turn_helix, mercury resistance
OKAIHIGN_02670 5.2e-35 S Protein of unknown function (DUF3781)
OKAIHIGN_02671 1.7e-38
OKAIHIGN_02672 4.3e-80 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
OKAIHIGN_02673 1.6e-33 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OKAIHIGN_02675 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
OKAIHIGN_02676 4.7e-54 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
OKAIHIGN_02677 5.8e-243 2.1.1.72 V type I restriction-modification system
OKAIHIGN_02682 7.8e-74
OKAIHIGN_02683 1.4e-26
OKAIHIGN_02684 5.9e-21 S Mor transcription activator family
OKAIHIGN_02685 2.3e-148 L Phage integrase SAM-like domain
OKAIHIGN_02686 3.4e-55 3.1.3.16 S Protein of unknown function (DUF1643)
OKAIHIGN_02687 1.7e-90 L Phage integrase SAM-like domain
OKAIHIGN_02689 7.6e-209 S Phage plasmid primase, P4
OKAIHIGN_02691 8.9e-19 polA 2.7.7.7 L 3'-5' exonuclease
OKAIHIGN_02693 5.2e-71 yugI 5.3.1.9 J general stress protein
OKAIHIGN_02694 3.5e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OKAIHIGN_02695 6.1e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
OKAIHIGN_02696 2.9e-122 dedA S SNARE-like domain protein
OKAIHIGN_02697 3.4e-13 K helix_turn_helix, mercury resistance
OKAIHIGN_02698 1.8e-63 IQ Enoyl-(Acyl carrier protein) reductase
OKAIHIGN_02699 4.5e-112 ytbE C Aldo keto reductase
OKAIHIGN_02700 4.8e-140 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
OKAIHIGN_02701 2.4e-251 yfnA E Amino Acid
OKAIHIGN_02702 2e-234 M domain protein
OKAIHIGN_02703 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
OKAIHIGN_02704 7.7e-88 S WxL domain surface cell wall-binding
OKAIHIGN_02705 6.5e-116 S Protein of unknown function (DUF1461)
OKAIHIGN_02706 1.3e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OKAIHIGN_02707 2.9e-82 yutD S Protein of unknown function (DUF1027)
OKAIHIGN_02708 3.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OKAIHIGN_02709 5.3e-115 S Calcineurin-like phosphoesterase
OKAIHIGN_02710 6.2e-154 yeaE S Aldo keto
OKAIHIGN_02711 8.5e-257 cycA E Amino acid permease
OKAIHIGN_02712 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OKAIHIGN_02713 2e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
OKAIHIGN_02714 7.1e-74
OKAIHIGN_02716 1.2e-79
OKAIHIGN_02717 7.6e-49 comGC U competence protein ComGC
OKAIHIGN_02718 3.8e-168 comGB NU type II secretion system
OKAIHIGN_02719 1.2e-172 comGA NU Type II IV secretion system protein
OKAIHIGN_02720 2.6e-132 yebC K Transcriptional regulatory protein
OKAIHIGN_02721 6.2e-266 glnPH2 P ABC transporter permease
OKAIHIGN_02722 8.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
OKAIHIGN_02723 5.7e-128
OKAIHIGN_02724 4.6e-180 ccpA K catabolite control protein A
OKAIHIGN_02725 2.7e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
OKAIHIGN_02726 9.5e-43
OKAIHIGN_02727 6.9e-34 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OKAIHIGN_02728 4.1e-156 ykuT M mechanosensitive ion channel
OKAIHIGN_02730 8.9e-243 U Major Facilitator Superfamily
OKAIHIGN_02731 1.4e-47 K helix_turn_helix, Arsenical Resistance Operon Repressor
OKAIHIGN_02733 1.8e-84 ykuL S (CBS) domain
OKAIHIGN_02734 7.3e-97 S Phosphoesterase
OKAIHIGN_02735 1.4e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OKAIHIGN_02736 4.7e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OKAIHIGN_02737 6.7e-90 yslB S Protein of unknown function (DUF2507)
OKAIHIGN_02738 2.7e-54 trxA O Belongs to the thioredoxin family
OKAIHIGN_02739 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OKAIHIGN_02740 3.2e-87 cvpA S Colicin V production protein
OKAIHIGN_02741 7.3e-37 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OKAIHIGN_02742 1.6e-51 yrzB S Belongs to the UPF0473 family
OKAIHIGN_02743 1.5e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OKAIHIGN_02744 6.4e-44 yrzL S Belongs to the UPF0297 family
OKAIHIGN_02745 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OKAIHIGN_02746 1.8e-251 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OKAIHIGN_02747 9e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
OKAIHIGN_02748 1.5e-179 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OKAIHIGN_02749 1.1e-26 yajC U Preprotein translocase
OKAIHIGN_02750 3e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OKAIHIGN_02751 4.1e-200 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OKAIHIGN_02752 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OKAIHIGN_02753 1.4e-107 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OKAIHIGN_02754 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OKAIHIGN_02755 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OKAIHIGN_02756 5.1e-150 ymdB S YmdB-like protein
OKAIHIGN_02757 4e-223 rny S Endoribonuclease that initiates mRNA decay
OKAIHIGN_02759 6.8e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OKAIHIGN_02760 3.7e-227 cinA 3.5.1.42 S Belongs to the CinA family
OKAIHIGN_02761 1e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OKAIHIGN_02762 2.6e-65 ymfM S Domain of unknown function (DUF4115)
OKAIHIGN_02763 1.1e-245 ymfH S Peptidase M16
OKAIHIGN_02764 6.4e-235 ymfF S Peptidase M16 inactive domain protein
OKAIHIGN_02765 1.4e-158 aatB ET ABC transporter substrate-binding protein
OKAIHIGN_02766 4.2e-94 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
OKAIHIGN_02767 2.5e-110 glnP P ABC transporter permease
OKAIHIGN_02768 4.1e-147 minD D Belongs to the ParA family
OKAIHIGN_02769 8.2e-117 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OKAIHIGN_02770 3.2e-92 mreD M rod shape-determining protein MreD
OKAIHIGN_02771 9.7e-139 mreC M Involved in formation and maintenance of cell shape
OKAIHIGN_02772 9.6e-162 mreB D cell shape determining protein MreB
OKAIHIGN_02773 8.1e-117 radC L DNA repair protein
OKAIHIGN_02774 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OKAIHIGN_02775 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OKAIHIGN_02776 3.5e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OKAIHIGN_02777 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OKAIHIGN_02778 7.2e-214 iscS2 2.8.1.7 E Aminotransferase class V
OKAIHIGN_02779 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OKAIHIGN_02780 2.4e-83 ytsP 1.8.4.14 T GAF domain-containing protein
OKAIHIGN_02781 4.8e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OKAIHIGN_02782 7.1e-61 KLT serine threonine protein kinase
OKAIHIGN_02783 1.3e-110 yktB S Belongs to the UPF0637 family
OKAIHIGN_02784 7.1e-80 yueI S Protein of unknown function (DUF1694)
OKAIHIGN_02785 1.2e-236 rarA L recombination factor protein RarA
OKAIHIGN_02786 3.2e-41
OKAIHIGN_02787 1e-81 usp6 T universal stress protein
OKAIHIGN_02788 7.9e-160 2.3.1.19 K Helix-turn-helix XRE-family like proteins
OKAIHIGN_02789 9.9e-299 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
OKAIHIGN_02790 1.2e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OKAIHIGN_02791 3e-176 S Protein of unknown function (DUF2785)
OKAIHIGN_02792 3.9e-140 f42a O Band 7 protein
OKAIHIGN_02793 1.9e-49 gcsH2 E glycine cleavage
OKAIHIGN_02794 1.1e-220 rodA D Belongs to the SEDS family
OKAIHIGN_02795 1.1e-33 S Protein of unknown function (DUF2969)
OKAIHIGN_02796 1.1e-52 yidD S Could be involved in insertion of integral membrane proteins into the membrane
OKAIHIGN_02797 1.8e-179 mbl D Cell shape determining protein MreB Mrl
OKAIHIGN_02798 1.3e-243 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OKAIHIGN_02799 4.3e-33 ywzB S Protein of unknown function (DUF1146)
OKAIHIGN_02800 1.1e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OKAIHIGN_02801 5.3e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OKAIHIGN_02802 7.3e-161 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OKAIHIGN_02803 1.7e-287 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OKAIHIGN_02804 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OKAIHIGN_02805 3.4e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OKAIHIGN_02806 7.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OKAIHIGN_02807 6.1e-126 atpB C it plays a direct role in the translocation of protons across the membrane
OKAIHIGN_02808 1.5e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OKAIHIGN_02809 7.8e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OKAIHIGN_02810 7.2e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OKAIHIGN_02811 1.7e-151 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OKAIHIGN_02812 7.9e-186 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OKAIHIGN_02813 8.5e-110 tdk 2.7.1.21 F thymidine kinase
OKAIHIGN_02814 1.2e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
OKAIHIGN_02815 1.3e-133 cobQ S glutamine amidotransferase
OKAIHIGN_02816 4.3e-194 ampC V Beta-lactamase
OKAIHIGN_02817 0.0 yfiC V ABC transporter
OKAIHIGN_02818 0.0 lmrA V ABC transporter, ATP-binding protein
OKAIHIGN_02819 8.9e-56
OKAIHIGN_02820 8.7e-09
OKAIHIGN_02821 3e-148 2.7.7.65 T diguanylate cyclase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)