ORF_ID e_value Gene_name EC_number CAZy COGs Description
HFLFIKEJ_00001 2.2e-159 map 3.4.11.18 E Methionine Aminopeptidase
HFLFIKEJ_00002 5.8e-194 M Glycosyltransferase like family 2
HFLFIKEJ_00004 4.5e-29
HFLFIKEJ_00005 4.9e-125 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HFLFIKEJ_00006 6.8e-198 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HFLFIKEJ_00007 8.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HFLFIKEJ_00009 6.8e-307 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFLFIKEJ_00010 0.0 S Bacterial membrane protein YfhO
HFLFIKEJ_00011 2.6e-308 S Psort location CytoplasmicMembrane, score
HFLFIKEJ_00012 1.6e-83 S Fic/DOC family
HFLFIKEJ_00013 2.1e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HFLFIKEJ_00014 2.3e-108
HFLFIKEJ_00015 8.6e-168 yqjA S Putative aromatic acid exporter C-terminal domain
HFLFIKEJ_00016 4.7e-64 K Helix-turn-helix XRE-family like proteins
HFLFIKEJ_00017 1e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
HFLFIKEJ_00018 1.3e-223 queG 1.17.99.6 C Domain of unknown function (DUF1730)
HFLFIKEJ_00019 1.4e-62
HFLFIKEJ_00020 1.4e-87 bioY S BioY family
HFLFIKEJ_00022 4.2e-102 Q methyltransferase
HFLFIKEJ_00023 4.1e-96 T Sh3 type 3 domain protein
HFLFIKEJ_00024 1.6e-114 yfeJ 6.3.5.2 F glutamine amidotransferase
HFLFIKEJ_00025 2.3e-136 S Uncharacterized protein conserved in bacteria (DUF2263)
HFLFIKEJ_00026 2.2e-257 yhdP S Transporter associated domain
HFLFIKEJ_00027 1.9e-144 S Alpha beta hydrolase
HFLFIKEJ_00028 7.8e-196 I Acyltransferase
HFLFIKEJ_00029 6.9e-262 lmrB EGP Major facilitator Superfamily
HFLFIKEJ_00030 2.6e-83 S Domain of unknown function (DUF4811)
HFLFIKEJ_00031 1.5e-95 maf D nucleoside-triphosphate diphosphatase activity
HFLFIKEJ_00032 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFLFIKEJ_00033 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFLFIKEJ_00034 1.2e-97 yacP S YacP-like NYN domain
HFLFIKEJ_00035 7e-144 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFLFIKEJ_00036 5.5e-74 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFLFIKEJ_00037 9.3e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFLFIKEJ_00038 7.9e-144 K sequence-specific DNA binding
HFLFIKEJ_00039 1.8e-246 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HFLFIKEJ_00040 2.8e-105
HFLFIKEJ_00042 2.8e-258 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFLFIKEJ_00043 1.9e-139 yhfC S Putative membrane peptidase family (DUF2324)
HFLFIKEJ_00044 1.6e-156 S Membrane
HFLFIKEJ_00045 1.8e-60 K helix_turn_helix gluconate operon transcriptional repressor
HFLFIKEJ_00046 3.3e-226 inlJ M MucBP domain
HFLFIKEJ_00047 4e-113 K sequence-specific DNA binding
HFLFIKEJ_00048 1.8e-201 yacL S domain protein
HFLFIKEJ_00049 8.5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFLFIKEJ_00050 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
HFLFIKEJ_00051 4.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HFLFIKEJ_00052 5.7e-172 corA P CorA-like Mg2+ transporter protein
HFLFIKEJ_00053 6.2e-154 rrmA 2.1.1.187 H Methyltransferase
HFLFIKEJ_00054 6.2e-208 yaaN P Toxic anion resistance protein (TelA)
HFLFIKEJ_00055 6.9e-116 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HFLFIKEJ_00056 3.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HFLFIKEJ_00057 5.8e-34
HFLFIKEJ_00058 2.4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFLFIKEJ_00059 9.9e-219 iscS 2.8.1.7 E Aminotransferase class V
HFLFIKEJ_00060 2.6e-58 XK27_04120 S Putative amino acid metabolism
HFLFIKEJ_00061 0.0 uvrA2 L ABC transporter
HFLFIKEJ_00062 2.8e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFLFIKEJ_00064 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HFLFIKEJ_00065 1.4e-116 S Repeat protein
HFLFIKEJ_00066 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFLFIKEJ_00067 4.6e-243 els S Sterol carrier protein domain
HFLFIKEJ_00068 8.5e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HFLFIKEJ_00069 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFLFIKEJ_00070 4.9e-31 ykzG S Belongs to the UPF0356 family
HFLFIKEJ_00073 1.5e-115 ywnB S NmrA-like family
HFLFIKEJ_00074 6.6e-07
HFLFIKEJ_00075 4.7e-199
HFLFIKEJ_00076 3e-153 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFLFIKEJ_00077 2.2e-88 S Short repeat of unknown function (DUF308)
HFLFIKEJ_00079 5.9e-121 yrkL S Flavodoxin-like fold
HFLFIKEJ_00080 9.6e-149 cytC6 I alpha/beta hydrolase fold
HFLFIKEJ_00081 3.5e-211 mutY L A G-specific adenine glycosylase
HFLFIKEJ_00082 3.1e-86 hsp1 O Belongs to the small heat shock protein (HSP20) family
HFLFIKEJ_00083 1.3e-14
HFLFIKEJ_00084 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HFLFIKEJ_00085 3.4e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HFLFIKEJ_00086 3.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HFLFIKEJ_00087 1.9e-141 lacR K DeoR C terminal sensor domain
HFLFIKEJ_00088 6.1e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HFLFIKEJ_00089 9.9e-94 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HFLFIKEJ_00090 7.6e-212 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFLFIKEJ_00091 1.4e-300 frvR K Mga helix-turn-helix domain
HFLFIKEJ_00092 7.7e-296 frvR K Mga helix-turn-helix domain
HFLFIKEJ_00093 9.4e-267 lysP E amino acid
HFLFIKEJ_00095 9e-130 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HFLFIKEJ_00096 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HFLFIKEJ_00097 1.6e-97
HFLFIKEJ_00098 4.3e-95 2.3.1.128 J Acetyltransferase (GNAT) domain
HFLFIKEJ_00099 9.5e-189 S Bacterial protein of unknown function (DUF916)
HFLFIKEJ_00100 9.9e-103
HFLFIKEJ_00101 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HFLFIKEJ_00102 8.1e-157 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HFLFIKEJ_00103 3.4e-157 I alpha/beta hydrolase fold
HFLFIKEJ_00104 1.1e-31
HFLFIKEJ_00106 1.2e-79 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HFLFIKEJ_00107 3.4e-138 plnD K LytTr DNA-binding domain
HFLFIKEJ_00110 1.4e-44 spiA S Enterocin A Immunity
HFLFIKEJ_00111 2.9e-20
HFLFIKEJ_00115 5.8e-133 S CAAX protease self-immunity
HFLFIKEJ_00116 2.5e-69 K Transcriptional regulator
HFLFIKEJ_00117 1.4e-251 EGP Major Facilitator Superfamily
HFLFIKEJ_00118 2.4e-53
HFLFIKEJ_00119 2.3e-54 S Enterocin A Immunity
HFLFIKEJ_00120 2.6e-180 S Aldo keto reductase
HFLFIKEJ_00121 1.2e-129 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HFLFIKEJ_00122 1.5e-214 yqiG C Oxidoreductase
HFLFIKEJ_00123 3e-16 S Short C-terminal domain
HFLFIKEJ_00124 3.3e-253 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFLFIKEJ_00125 2.2e-135
HFLFIKEJ_00127 5e-148 P Belongs to the nlpA lipoprotein family
HFLFIKEJ_00128 9.1e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFLFIKEJ_00129 1.1e-105 metI P ABC transporter permease
HFLFIKEJ_00130 1.9e-141 sufC O FeS assembly ATPase SufC
HFLFIKEJ_00131 1.3e-190 sufD O FeS assembly protein SufD
HFLFIKEJ_00132 8.1e-224 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFLFIKEJ_00133 7.2e-77 nifU C SUF system FeS assembly protein, NifU family
HFLFIKEJ_00134 1.2e-279 sufB O assembly protein SufB
HFLFIKEJ_00135 1.8e-26
HFLFIKEJ_00136 8.4e-66 yueI S Protein of unknown function (DUF1694)
HFLFIKEJ_00137 1.2e-180 S Protein of unknown function (DUF2785)
HFLFIKEJ_00138 4.4e-158 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HFLFIKEJ_00139 1.5e-83 usp6 T universal stress protein
HFLFIKEJ_00140 1.7e-39
HFLFIKEJ_00141 6e-239 rarA L recombination factor protein RarA
HFLFIKEJ_00142 0.0 6.3.2.2, 6.3.2.4 M Mur ligase middle domain protein
HFLFIKEJ_00143 1.7e-72 yueI S Protein of unknown function (DUF1694)
HFLFIKEJ_00144 1.6e-106 yktB S Belongs to the UPF0637 family
HFLFIKEJ_00145 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HFLFIKEJ_00146 1.6e-149 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HFLFIKEJ_00147 4.8e-120 G Phosphoglycerate mutase family
HFLFIKEJ_00148 1.2e-154 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFLFIKEJ_00149 1.7e-165 IQ NAD dependent epimerase/dehydratase family
HFLFIKEJ_00150 2.7e-137 pnuC H nicotinamide mononucleotide transporter
HFLFIKEJ_00151 8.9e-133 dck 2.7.1.74 F deoxynucleoside kinase
HFLFIKEJ_00152 5.8e-157 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HFLFIKEJ_00153 3.6e-307 oppA E ABC transporter, substratebinding protein
HFLFIKEJ_00154 5.6e-153 T GHKL domain
HFLFIKEJ_00155 4.7e-120 T Transcriptional regulatory protein, C terminal
HFLFIKEJ_00156 2.7e-166 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
HFLFIKEJ_00157 4.1e-128 S ABC-2 family transporter protein
HFLFIKEJ_00158 9.7e-158 K Transcriptional regulator
HFLFIKEJ_00159 3.6e-78 yphH S Cupin domain
HFLFIKEJ_00160 2.7e-54 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HFLFIKEJ_00161 3e-105 K Psort location Cytoplasmic, score
HFLFIKEJ_00162 1.7e-162 2.3.1.128 K Acetyltransferase (GNAT) domain
HFLFIKEJ_00163 6.5e-84 K Acetyltransferase (GNAT) domain
HFLFIKEJ_00164 9.7e-155 S Uncharacterised protein, DegV family COG1307
HFLFIKEJ_00165 3.1e-102 desR K helix_turn_helix, Lux Regulon
HFLFIKEJ_00166 7.5e-200 desK 2.7.13.3 T Histidine kinase
HFLFIKEJ_00167 1.5e-127 yvfS V ABC-2 type transporter
HFLFIKEJ_00168 5.7e-158 yvfR V ABC transporter
HFLFIKEJ_00169 2.5e-275
HFLFIKEJ_00170 2.5e-181
HFLFIKEJ_00171 0.0 D Putative exonuclease SbcCD, C subunit
HFLFIKEJ_00172 2.2e-132 S Protein of unknown function C-terminus (DUF2399)
HFLFIKEJ_00173 2.2e-82 K Acetyltransferase (GNAT) domain
HFLFIKEJ_00174 0.0 yhgF K Tex-like protein N-terminal domain protein
HFLFIKEJ_00175 7.4e-82
HFLFIKEJ_00176 1.1e-138 puuD S peptidase C26
HFLFIKEJ_00177 1e-227 steT E Amino acid permease
HFLFIKEJ_00180 2.1e-135 L Transposase DDE domain
HFLFIKEJ_00181 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
HFLFIKEJ_00182 4e-165 XK27_00670 S ABC transporter substrate binding protein
HFLFIKEJ_00183 2.6e-164 XK27_00670 S ABC transporter
HFLFIKEJ_00184 2.9e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HFLFIKEJ_00185 5.2e-142 cmpC S ABC transporter, ATP-binding protein
HFLFIKEJ_00186 1.8e-170 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
HFLFIKEJ_00187 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HFLFIKEJ_00189 4e-181 ykcC GT2 M Glycosyl transferase family 2
HFLFIKEJ_00190 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HFLFIKEJ_00191 6.4e-72 S GtrA-like protein
HFLFIKEJ_00192 1.6e-251 yxbA 6.3.1.12 S ATP-grasp enzyme
HFLFIKEJ_00193 1.1e-67 usp1 T Universal stress protein family
HFLFIKEJ_00194 1e-09
HFLFIKEJ_00195 1.1e-135 sfsA S Belongs to the SfsA family
HFLFIKEJ_00196 1e-221 gbuA 3.6.3.32 E glycine betaine
HFLFIKEJ_00197 9.4e-126 proW E glycine betaine
HFLFIKEJ_00198 3.6e-168 gbuC E glycine betaine
HFLFIKEJ_00199 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HFLFIKEJ_00200 1.5e-65 gtcA S Teichoic acid glycosylation protein
HFLFIKEJ_00201 1.1e-127 srtA 3.4.22.70 M Sortase family
HFLFIKEJ_00202 6.4e-180 K AI-2E family transporter
HFLFIKEJ_00203 3.7e-199 pbpX1 V Beta-lactamase
HFLFIKEJ_00204 6.8e-126 S zinc-ribbon domain
HFLFIKEJ_00205 4.4e-29
HFLFIKEJ_00206 3.5e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFLFIKEJ_00207 1.9e-83 F NUDIX domain
HFLFIKEJ_00208 1.2e-103 rmaB K Transcriptional regulator, MarR family
HFLFIKEJ_00209 3.1e-185
HFLFIKEJ_00210 1.9e-170 S Putative esterase
HFLFIKEJ_00211 4.1e-11 S response to antibiotic
HFLFIKEJ_00212 1.3e-67 K MarR family
HFLFIKEJ_00213 4.3e-26
HFLFIKEJ_00214 3.1e-84 yetL K helix_turn_helix multiple antibiotic resistance protein
HFLFIKEJ_00215 4.9e-63 P Rhodanese-like domain
HFLFIKEJ_00216 4.9e-229 bdhA C Iron-containing alcohol dehydrogenase
HFLFIKEJ_00217 1.9e-191 I carboxylic ester hydrolase activity
HFLFIKEJ_00218 9e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HFLFIKEJ_00219 2.1e-76 marR K Winged helix DNA-binding domain
HFLFIKEJ_00220 1.6e-174 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFLFIKEJ_00221 4.5e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFLFIKEJ_00222 2.4e-173 fabK 1.3.1.9 S Nitronate monooxygenase
HFLFIKEJ_00223 2.7e-166 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HFLFIKEJ_00224 1.1e-125 IQ reductase
HFLFIKEJ_00225 3.1e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFLFIKEJ_00226 2.3e-51 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFLFIKEJ_00227 1.2e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFLFIKEJ_00228 6.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HFLFIKEJ_00229 3.1e-150 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFLFIKEJ_00230 2e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HFLFIKEJ_00231 6.5e-234 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HFLFIKEJ_00232 2.1e-157 azoB GM NmrA-like family
HFLFIKEJ_00234 3.2e-299 scrB 3.2.1.26 GH32 G invertase
HFLFIKEJ_00235 1.9e-178 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HFLFIKEJ_00236 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HFLFIKEJ_00237 0.0 scrA 2.7.1.211 G phosphotransferase system
HFLFIKEJ_00238 0.0 pip V domain protein
HFLFIKEJ_00239 4.1e-212 ykiI
HFLFIKEJ_00240 1.4e-104 S Putative inner membrane protein (DUF1819)
HFLFIKEJ_00241 9.7e-106 S Domain of unknown function (DUF1788)
HFLFIKEJ_00242 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HFLFIKEJ_00243 4.6e-139 cad S FMN_bind
HFLFIKEJ_00244 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HFLFIKEJ_00245 1.7e-81 ynhH S NusG domain II
HFLFIKEJ_00246 5.2e-99 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HFLFIKEJ_00247 8.4e-179 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFLFIKEJ_00248 1.2e-80
HFLFIKEJ_00249 3.3e-46 T Calcineurin-like phosphoesterase superfamily domain
HFLFIKEJ_00250 2.1e-157 V ATPases associated with a variety of cellular activities
HFLFIKEJ_00251 2.1e-219
HFLFIKEJ_00252 1.8e-193
HFLFIKEJ_00253 1.3e-122 1.5.1.40 S Rossmann-like domain
HFLFIKEJ_00254 4.2e-192 XK27_00915 C Luciferase-like monooxygenase
HFLFIKEJ_00255 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HFLFIKEJ_00256 3.4e-43
HFLFIKEJ_00257 7e-152 V Beta-lactamase
HFLFIKEJ_00258 1.6e-191 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HFLFIKEJ_00259 8.7e-136 H Protein of unknown function (DUF1698)
HFLFIKEJ_00260 1.1e-139 puuD S peptidase C26
HFLFIKEJ_00261 1.3e-106 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HFLFIKEJ_00262 1.3e-78 K Psort location Cytoplasmic, score
HFLFIKEJ_00263 4.8e-257 6.3.1.2 E Glutamine synthetase N-terminal domain
HFLFIKEJ_00264 1.5e-222 S Amidohydrolase
HFLFIKEJ_00265 2.4e-248 E Amino acid permease
HFLFIKEJ_00266 2.5e-74 K helix_turn_helix, mercury resistance
HFLFIKEJ_00267 9.2e-161 morA2 S reductase
HFLFIKEJ_00268 2.6e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HFLFIKEJ_00269 4e-59 hxlR K Transcriptional regulator, HxlR family
HFLFIKEJ_00270 2e-127 S membrane transporter protein
HFLFIKEJ_00271 7.5e-61
HFLFIKEJ_00272 1.5e-248 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFLFIKEJ_00273 1.6e-29 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFLFIKEJ_00274 5.6e-188 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLFIKEJ_00275 4.6e-38 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_00276 1.8e-212 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
HFLFIKEJ_00277 1.1e-196
HFLFIKEJ_00278 5.4e-130 XK27_12140 V ATPases associated with a variety of cellular activities
HFLFIKEJ_00279 6e-299 S Psort location CytoplasmicMembrane, score
HFLFIKEJ_00280 2.2e-125 K Transcriptional regulatory protein, C terminal
HFLFIKEJ_00281 3.3e-195 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HFLFIKEJ_00282 3.6e-160 V ATPases associated with a variety of cellular activities
HFLFIKEJ_00283 1.6e-197
HFLFIKEJ_00284 2.3e-105
HFLFIKEJ_00285 0.0 pepN 3.4.11.2 E aminopeptidase
HFLFIKEJ_00286 8.4e-276 ycaM E amino acid
HFLFIKEJ_00287 2.2e-238 G MFS/sugar transport protein
HFLFIKEJ_00288 7.6e-91 S Protein of unknown function (DUF1440)
HFLFIKEJ_00289 5.1e-161 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HFLFIKEJ_00290 2.7e-174 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HFLFIKEJ_00292 1.5e-138
HFLFIKEJ_00294 1e-212 metC 4.4.1.8 E cystathionine
HFLFIKEJ_00295 8.6e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HFLFIKEJ_00296 2.2e-120 tcyB E ABC transporter
HFLFIKEJ_00297 2.2e-117
HFLFIKEJ_00298 2.5e-253 brnQ U Component of the transport system for branched-chain amino acids
HFLFIKEJ_00299 3.5e-75 S WxL domain surface cell wall-binding
HFLFIKEJ_00300 1.2e-172 S Cell surface protein
HFLFIKEJ_00301 5.5e-43
HFLFIKEJ_00302 3.2e-244 XK27_00720 S Leucine-rich repeat (LRR) protein
HFLFIKEJ_00304 5.3e-80 perR P Belongs to the Fur family
HFLFIKEJ_00305 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFLFIKEJ_00306 5.1e-44 ykuJ S Protein of unknown function (DUF1797)
HFLFIKEJ_00307 1e-218 patA 2.6.1.1 E Aminotransferase
HFLFIKEJ_00308 4.5e-167 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFLFIKEJ_00309 1.8e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
HFLFIKEJ_00310 5.8e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HFLFIKEJ_00311 1.1e-297 ybeC E amino acid
HFLFIKEJ_00312 1.3e-93 sigH K Sigma-70 region 2
HFLFIKEJ_00321 2e-17
HFLFIKEJ_00322 5.3e-279 mntH P H( )-stimulated, divalent metal cation uptake system
HFLFIKEJ_00323 0.0 pacL P P-type ATPase
HFLFIKEJ_00324 9.8e-64
HFLFIKEJ_00325 1.2e-225 EGP Major Facilitator Superfamily
HFLFIKEJ_00326 4.2e-311 mco Q Multicopper oxidase
HFLFIKEJ_00327 1e-24
HFLFIKEJ_00328 3.2e-110 2.5.1.105 P Cation efflux family
HFLFIKEJ_00329 8.7e-51 czrA K Transcriptional regulator, ArsR family
HFLFIKEJ_00330 1.2e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
HFLFIKEJ_00331 9.5e-145 mtsB U ABC 3 transport family
HFLFIKEJ_00332 1.9e-130 mntB 3.6.3.35 P ABC transporter
HFLFIKEJ_00333 5.1e-119 S (CBS) domain
HFLFIKEJ_00334 6.8e-130 yciB M ErfK YbiS YcfS YnhG
HFLFIKEJ_00335 1.2e-279 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HFLFIKEJ_00336 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
HFLFIKEJ_00337 1.7e-85 S QueT transporter
HFLFIKEJ_00338 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
HFLFIKEJ_00339 2.4e-37
HFLFIKEJ_00340 3.5e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFLFIKEJ_00341 1.7e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFLFIKEJ_00342 4.5e-264 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFLFIKEJ_00343 2.5e-132 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HFLFIKEJ_00344 4.2e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HFLFIKEJ_00345 8.7e-50
HFLFIKEJ_00346 4.7e-235 YSH1 S Metallo-beta-lactamase superfamily
HFLFIKEJ_00347 4.4e-239 malE G Bacterial extracellular solute-binding protein
HFLFIKEJ_00348 4.2e-147 malF G Binding-protein-dependent transport system inner membrane component
HFLFIKEJ_00349 2.6e-166 malG P ABC-type sugar transport systems, permease components
HFLFIKEJ_00350 1e-193 malK P ATPases associated with a variety of cellular activities
HFLFIKEJ_00351 4.4e-103 3.2.2.20 K Acetyltransferase (GNAT) domain
HFLFIKEJ_00352 9e-92 yxjI
HFLFIKEJ_00353 2e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
HFLFIKEJ_00354 4.6e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFLFIKEJ_00355 4.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HFLFIKEJ_00356 1.2e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HFLFIKEJ_00357 1.5e-166 natA S ABC transporter, ATP-binding protein
HFLFIKEJ_00358 2e-217 ysdA CP ABC-2 family transporter protein
HFLFIKEJ_00359 3.1e-98 dnaQ 2.7.7.7 L DNA polymerase III
HFLFIKEJ_00360 1.6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
HFLFIKEJ_00361 9.5e-158 murB 1.3.1.98 M Cell wall formation
HFLFIKEJ_00362 0.0 yjcE P Sodium proton antiporter
HFLFIKEJ_00363 2.9e-96 puuR K Cupin domain
HFLFIKEJ_00364 4.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFLFIKEJ_00365 1.7e-148 potB P ABC transporter permease
HFLFIKEJ_00366 8.9e-145 potC P ABC transporter permease
HFLFIKEJ_00367 1.4e-206 potD P ABC transporter
HFLFIKEJ_00368 5.2e-14 T SpoVT / AbrB like domain
HFLFIKEJ_00370 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HFLFIKEJ_00371 5.8e-118 K Transcriptional regulator
HFLFIKEJ_00372 2.7e-184 V ABC transporter
HFLFIKEJ_00373 2.1e-126 V AAA domain, putative AbiEii toxin, Type IV TA system
HFLFIKEJ_00374 1e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFLFIKEJ_00375 7e-166 ybbR S YbbR-like protein
HFLFIKEJ_00376 9.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFLFIKEJ_00377 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFLFIKEJ_00378 0.0 pepF2 E Oligopeptidase F
HFLFIKEJ_00379 9.7e-91 S VanZ like family
HFLFIKEJ_00380 3.4e-132 yebC K Transcriptional regulatory protein
HFLFIKEJ_00381 1.5e-131 comGA NU Type II IV secretion system protein
HFLFIKEJ_00382 1.2e-164 comGB NU type II secretion system
HFLFIKEJ_00383 5.1e-48
HFLFIKEJ_00385 1.1e-47
HFLFIKEJ_00386 1.1e-80
HFLFIKEJ_00387 4.6e-49
HFLFIKEJ_00388 4.5e-183 ytxK 2.1.1.72 L N-6 DNA Methylase
HFLFIKEJ_00389 3.3e-72
HFLFIKEJ_00390 1.2e-247 cycA E Amino acid permease
HFLFIKEJ_00391 3.8e-142 arbV 2.3.1.51 I Phosphate acyltransferases
HFLFIKEJ_00392 9.5e-163 arbx M Glycosyl transferase family 8
HFLFIKEJ_00393 1.5e-180 arbY M family 8
HFLFIKEJ_00394 9.1e-164 arbZ I Phosphate acyltransferases
HFLFIKEJ_00395 0.0 rafA 3.2.1.22 G alpha-galactosidase
HFLFIKEJ_00396 1.2e-213 sip L Belongs to the 'phage' integrase family
HFLFIKEJ_00399 2.1e-29
HFLFIKEJ_00400 4.4e-17
HFLFIKEJ_00401 1.1e-21
HFLFIKEJ_00403 1.9e-23
HFLFIKEJ_00404 2.9e-148 L Bifunctional DNA primase/polymerase, N-terminal
HFLFIKEJ_00405 1.9e-300 S Phage plasmid primase, P4
HFLFIKEJ_00406 3.9e-51 S Phage head-tail joining protein
HFLFIKEJ_00408 5.1e-24 L Phage-associated protein
HFLFIKEJ_00409 5.3e-78 terS L Phage terminase, small subunit
HFLFIKEJ_00410 0.0 terL S overlaps another CDS with the same product name
HFLFIKEJ_00411 2.5e-20
HFLFIKEJ_00412 1e-218 S Phage portal protein
HFLFIKEJ_00413 1.8e-34
HFLFIKEJ_00414 2.8e-27
HFLFIKEJ_00415 5.7e-95 S ABC-type cobalt transport system, permease component
HFLFIKEJ_00416 8.7e-243 P ABC transporter
HFLFIKEJ_00417 1.2e-109 P cobalt transport
HFLFIKEJ_00418 1e-125 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HFLFIKEJ_00419 1.1e-81 thiW S Thiamine-precursor transporter protein (ThiW)
HFLFIKEJ_00420 5.4e-150 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFLFIKEJ_00421 3.7e-103 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFLFIKEJ_00422 3.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFLFIKEJ_00423 1.9e-272 E Amino acid permease
HFLFIKEJ_00424 2.8e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HFLFIKEJ_00425 8.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFLFIKEJ_00426 1.3e-269 rbsA 3.6.3.17 G ABC transporter
HFLFIKEJ_00427 1e-152 rbsC U Belongs to the binding-protein-dependent transport system permease family
HFLFIKEJ_00428 1.1e-157 rbsB G Periplasmic binding protein domain
HFLFIKEJ_00429 1.4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFLFIKEJ_00430 9.3e-44 K DNA-binding helix-turn-helix protein
HFLFIKEJ_00431 2.5e-36
HFLFIKEJ_00436 3.2e-155 S Protein of unknown function (DUF2785)
HFLFIKEJ_00437 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
HFLFIKEJ_00438 5e-53
HFLFIKEJ_00439 4.9e-87 V AAA domain, putative AbiEii toxin, Type IV TA system
HFLFIKEJ_00440 1.7e-80
HFLFIKEJ_00441 4.5e-62
HFLFIKEJ_00442 6.7e-94
HFLFIKEJ_00443 2.3e-238 ydiC1 EGP Major facilitator Superfamily
HFLFIKEJ_00444 2.1e-68 K helix_turn_helix multiple antibiotic resistance protein
HFLFIKEJ_00445 1.6e-102
HFLFIKEJ_00446 1e-28
HFLFIKEJ_00447 1e-165 GKT transcriptional antiterminator
HFLFIKEJ_00448 1e-45 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_00449 2.6e-204 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HFLFIKEJ_00450 5.1e-48
HFLFIKEJ_00451 1.2e-149 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HFLFIKEJ_00452 8.4e-87 6.3.4.4 S Zeta toxin
HFLFIKEJ_00453 6.2e-155 rihB 3.2.2.1 F Nucleoside
HFLFIKEJ_00454 9.8e-213 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
HFLFIKEJ_00455 3.4e-43 K Acetyltransferase (GNAT) family
HFLFIKEJ_00456 6.3e-118 K helix_turn_helix gluconate operon transcriptional repressor
HFLFIKEJ_00457 1.1e-88 4.1.2.13 G DeoC/LacD family aldolase
HFLFIKEJ_00458 9.9e-39 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HFLFIKEJ_00459 1.1e-180 2.7.1.53 G Belongs to the FGGY kinase family
HFLFIKEJ_00460 1.8e-91 IQ KR domain
HFLFIKEJ_00461 2.5e-125 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HFLFIKEJ_00462 2e-156 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
HFLFIKEJ_00463 4.4e-285 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLFIKEJ_00464 6.4e-154 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HFLFIKEJ_00465 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphotransferase system
HFLFIKEJ_00466 5.4e-239 sorE E Alcohol dehydrogenase GroES-like domain
HFLFIKEJ_00467 2.2e-163 sorC K sugar-binding domain protein
HFLFIKEJ_00468 4.1e-131 IQ NAD dependent epimerase/dehydratase family
HFLFIKEJ_00469 3.6e-62 sorF 2.7.1.191, 2.7.1.206 G PTS system fructose IIA component
HFLFIKEJ_00470 1.9e-78 sorB 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
HFLFIKEJ_00471 3.6e-130 sorA U PTS system sorbose-specific iic component
HFLFIKEJ_00472 1.2e-149 sorM G system, mannose fructose sorbose family IID component
HFLFIKEJ_00473 4.9e-149 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HFLFIKEJ_00474 1.4e-238 P transporter
HFLFIKEJ_00475 1.2e-172 C FAD dependent oxidoreductase
HFLFIKEJ_00476 4.9e-109 K Transcriptional regulator, LysR family
HFLFIKEJ_00477 1.1e-158 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HFLFIKEJ_00478 2.7e-97 S UPF0397 protein
HFLFIKEJ_00479 0.0 3.6.3.24 P ATP-binding cassette cobalt transporter
HFLFIKEJ_00480 7.2e-147 cbiQ P cobalt transport
HFLFIKEJ_00481 3.4e-25 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_00482 5.7e-21 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFLFIKEJ_00483 1.1e-162 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLFIKEJ_00484 1.7e-66 2.7.1.194, 2.7.1.202 GKT antiterminator
HFLFIKEJ_00485 5.7e-200 3.2.1.86 GT1 G Glycosyl hydrolase family 1
HFLFIKEJ_00486 3.5e-82 S Putative transposase
HFLFIKEJ_00487 7.8e-60 S Putative transposase
HFLFIKEJ_00488 1.8e-147 L PFAM Integrase catalytic region
HFLFIKEJ_00489 6.9e-90 L Helix-turn-helix domain
HFLFIKEJ_00490 2.8e-143 K helix_turn_helix, arabinose operon control protein
HFLFIKEJ_00491 0.0 K Sigma-54 interaction domain
HFLFIKEJ_00492 8.1e-57 levA G PTS system fructose IIA component
HFLFIKEJ_00493 1.1e-86 2.7.1.191 G PTS system sorbose subfamily IIB component
HFLFIKEJ_00494 4.1e-137 M PTS system sorbose-specific iic component
HFLFIKEJ_00495 1.8e-145 levD G PTS system mannose/fructose/sorbose family IID component
HFLFIKEJ_00496 3.5e-49
HFLFIKEJ_00498 9e-108 S Haloacid dehalogenase-like hydrolase
HFLFIKEJ_00499 6.2e-129 fruR K DeoR C terminal sensor domain
HFLFIKEJ_00500 3.9e-108 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HFLFIKEJ_00501 5.3e-93 hxlB 4.1.2.43, 5.3.1.27 M SIS domain
HFLFIKEJ_00502 0.0 mtlF 2.7.1.197 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLFIKEJ_00503 2.9e-173 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HFLFIKEJ_00504 8.2e-210 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HFLFIKEJ_00505 7.1e-223 G Major Facilitator Superfamily
HFLFIKEJ_00506 3.9e-227 E Peptidase family M20/M25/M40
HFLFIKEJ_00507 8.5e-98 K Transcriptional regulator, LysR family
HFLFIKEJ_00509 0.0 ebgA 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HFLFIKEJ_00510 2e-277 ygjI E Amino Acid
HFLFIKEJ_00511 6.3e-263 lysP E amino acid
HFLFIKEJ_00512 2.5e-163 K helix_turn_helix, arabinose operon control protein
HFLFIKEJ_00513 0.0 GK helix_turn_helix, arabinose operon control protein
HFLFIKEJ_00514 4.3e-209 G Major Facilitator Superfamily
HFLFIKEJ_00515 1.5e-272 abgB 3.5.1.47 S Peptidase dimerisation domain
HFLFIKEJ_00516 1.9e-18 hxlR K Transcriptional regulator, HxlR family
HFLFIKEJ_00517 4.4e-57 pnb C nitroreductase
HFLFIKEJ_00518 5.7e-119
HFLFIKEJ_00519 6.7e-08 K DNA-templated transcription, initiation
HFLFIKEJ_00520 1.3e-17 S YvrJ protein family
HFLFIKEJ_00521 1.8e-144 yqfZ 3.2.1.17 M hydrolase, family 25
HFLFIKEJ_00522 1.5e-86 ygfC K Bacterial regulatory proteins, tetR family
HFLFIKEJ_00523 1.9e-184 hrtB V ABC transporter permease
HFLFIKEJ_00524 1.3e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HFLFIKEJ_00525 5.5e-261 npr 1.11.1.1 C NADH oxidase
HFLFIKEJ_00526 3.7e-151 S hydrolase
HFLFIKEJ_00527 8.4e-44 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HFLFIKEJ_00528 5.6e-138 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HFLFIKEJ_00530 4.7e-10
HFLFIKEJ_00539 1.8e-78 ctsR K Belongs to the CtsR family
HFLFIKEJ_00540 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFLFIKEJ_00541 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFLFIKEJ_00542 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFLFIKEJ_00543 2e-83 3.4.23.43
HFLFIKEJ_00544 0.0 M domain protein
HFLFIKEJ_00545 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFLFIKEJ_00546 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFLFIKEJ_00547 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFLFIKEJ_00548 5.5e-197 yfjR K WYL domain
HFLFIKEJ_00549 3.8e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HFLFIKEJ_00550 1.2e-68 psiE S Phosphate-starvation-inducible E
HFLFIKEJ_00551 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HFLFIKEJ_00552 3e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFLFIKEJ_00553 5.9e-109 rplD J Forms part of the polypeptide exit tunnel
HFLFIKEJ_00554 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFLFIKEJ_00555 3.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFLFIKEJ_00556 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFLFIKEJ_00557 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFLFIKEJ_00558 3.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFLFIKEJ_00559 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFLFIKEJ_00560 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HFLFIKEJ_00561 1.4e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFLFIKEJ_00562 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFLFIKEJ_00563 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFLFIKEJ_00564 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFLFIKEJ_00565 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFLFIKEJ_00566 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFLFIKEJ_00567 4.6e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFLFIKEJ_00568 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFLFIKEJ_00569 1.7e-24 rpmD J Ribosomal protein L30
HFLFIKEJ_00570 2.2e-62 rplO J Binds to the 23S rRNA
HFLFIKEJ_00571 9.8e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFLFIKEJ_00572 1.4e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFLFIKEJ_00573 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFLFIKEJ_00574 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HFLFIKEJ_00575 2.1e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFLFIKEJ_00576 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFLFIKEJ_00577 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFLFIKEJ_00578 3.1e-60 rplQ J Ribosomal protein L17
HFLFIKEJ_00579 2.1e-120
HFLFIKEJ_00580 1.8e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFLFIKEJ_00581 3.2e-158 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFLFIKEJ_00582 3.6e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFLFIKEJ_00583 1.4e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFLFIKEJ_00585 1.1e-81 ccl S QueT transporter
HFLFIKEJ_00586 9.3e-127 IQ Enoyl-(Acyl carrier protein) reductase
HFLFIKEJ_00587 4.8e-37 XK27_01315 S Protein of unknown function (DUF2829)
HFLFIKEJ_00588 4.9e-48 K Cro/C1-type HTH DNA-binding domain
HFLFIKEJ_00589 3.3e-115 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
HFLFIKEJ_00590 1.5e-180 oppF P Belongs to the ABC transporter superfamily
HFLFIKEJ_00591 1.9e-197 oppD P Belongs to the ABC transporter superfamily
HFLFIKEJ_00592 3.1e-176 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFLFIKEJ_00593 3e-162 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFLFIKEJ_00594 7.4e-305 oppA E ABC transporter, substratebinding protein
HFLFIKEJ_00595 5.9e-253 EGP Major facilitator Superfamily
HFLFIKEJ_00596 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFLFIKEJ_00597 3.6e-263 ydiC1 EGP Major facilitator Superfamily
HFLFIKEJ_00598 1.5e-145 pstS P Phosphate
HFLFIKEJ_00599 8.2e-37 cspA K Cold shock protein
HFLFIKEJ_00600 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFLFIKEJ_00601 5.5e-80 divIVA D DivIVA protein
HFLFIKEJ_00602 6.4e-145 ylmH S S4 domain protein
HFLFIKEJ_00603 3.4e-43 yggT D integral membrane protein
HFLFIKEJ_00604 6.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFLFIKEJ_00605 3.1e-218 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFLFIKEJ_00606 6.9e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFLFIKEJ_00607 1.3e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFLFIKEJ_00608 1.4e-198 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFLFIKEJ_00609 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFLFIKEJ_00610 9.2e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFLFIKEJ_00611 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HFLFIKEJ_00612 6.2e-58 ftsL D cell division protein FtsL
HFLFIKEJ_00613 1.8e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFLFIKEJ_00614 4.8e-78 mraZ K Belongs to the MraZ family
HFLFIKEJ_00615 4.2e-53
HFLFIKEJ_00616 3.1e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFLFIKEJ_00618 8.1e-151 aatB ET ABC transporter substrate-binding protein
HFLFIKEJ_00619 3.8e-111 glnQ 3.6.3.21 E ABC transporter
HFLFIKEJ_00620 4.7e-109 artQ P ABC transporter permease
HFLFIKEJ_00621 1.3e-140 minD D Belongs to the ParA family
HFLFIKEJ_00622 1.2e-112 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HFLFIKEJ_00623 4.7e-83 mreD M rod shape-determining protein MreD
HFLFIKEJ_00624 8.5e-151 mreC M Involved in formation and maintenance of cell shape
HFLFIKEJ_00625 1e-179 mreB D cell shape determining protein MreB
HFLFIKEJ_00626 2e-118 radC L DNA repair protein
HFLFIKEJ_00627 8.7e-116 S Haloacid dehalogenase-like hydrolase
HFLFIKEJ_00628 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HFLFIKEJ_00629 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFLFIKEJ_00630 1.3e-114 rex K CoA binding domain
HFLFIKEJ_00631 1.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFLFIKEJ_00632 1.7e-215 iscS2 2.8.1.7 E Aminotransferase class V
HFLFIKEJ_00633 1.2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFLFIKEJ_00634 1.7e-84 ytsP 1.8.4.14 T GAF domain-containing protein
HFLFIKEJ_00635 2.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFLFIKEJ_00636 2.2e-16 S Domain of unknown function (DUF4263)
HFLFIKEJ_00637 1.4e-193 S Domain of unknown function DUF87
HFLFIKEJ_00638 9.7e-60 S SIR2-like domain
HFLFIKEJ_00640 1.3e-85
HFLFIKEJ_00641 1.9e-91 S MucBP domain
HFLFIKEJ_00642 1.2e-117 ywnB S NAD(P)H-binding
HFLFIKEJ_00645 1.9e-117 E lipolytic protein G-D-S-L family
HFLFIKEJ_00646 1.7e-82 feoA P FeoA
HFLFIKEJ_00647 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HFLFIKEJ_00648 2.7e-24 S Virus attachment protein p12 family
HFLFIKEJ_00649 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
HFLFIKEJ_00650 1e-56
HFLFIKEJ_00651 1.3e-231 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
HFLFIKEJ_00652 2.2e-260 G MFS/sugar transport protein
HFLFIKEJ_00653 2.1e-73 S function, without similarity to other proteins
HFLFIKEJ_00654 1.4e-65
HFLFIKEJ_00655 0.0 macB_3 V ABC transporter, ATP-binding protein
HFLFIKEJ_00656 3e-257 dtpT U amino acid peptide transporter
HFLFIKEJ_00657 1.7e-156 yjjH S Calcineurin-like phosphoesterase
HFLFIKEJ_00659 2.1e-261 mga K Mga helix-turn-helix domain
HFLFIKEJ_00660 6.5e-284 sprD D Domain of Unknown Function (DUF1542)
HFLFIKEJ_00661 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
HFLFIKEJ_00662 4.5e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFLFIKEJ_00663 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFLFIKEJ_00664 6.6e-125 gntR1 K UbiC transcription regulator-associated domain protein
HFLFIKEJ_00665 6.1e-274 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFLFIKEJ_00666 1.1e-220 V Beta-lactamase
HFLFIKEJ_00667 1.7e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFLFIKEJ_00668 2.7e-216 V Beta-lactamase
HFLFIKEJ_00670 0.0 pacL 3.6.3.8 P P-type ATPase
HFLFIKEJ_00671 3.1e-72
HFLFIKEJ_00672 8.9e-176 XK27_08835 S ABC transporter
HFLFIKEJ_00673 1.3e-128 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HFLFIKEJ_00674 7.3e-130 XK27_08845 S ABC transporter, ATP-binding protein
HFLFIKEJ_00675 5.2e-83 ydcK S Belongs to the SprT family
HFLFIKEJ_00676 6.6e-81 yodP 2.3.1.264 K FR47-like protein
HFLFIKEJ_00678 4.4e-101 S ECF transporter, substrate-specific component
HFLFIKEJ_00679 1.7e-210 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HFLFIKEJ_00680 4.1e-158 5.1.3.3 G Aldose 1-epimerase
HFLFIKEJ_00681 1.8e-101 V Restriction endonuclease
HFLFIKEJ_00682 3.3e-160 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HFLFIKEJ_00683 2.4e-47
HFLFIKEJ_00684 5e-210 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HFLFIKEJ_00685 1.4e-210 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
HFLFIKEJ_00686 2.5e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HFLFIKEJ_00687 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HFLFIKEJ_00688 1.3e-79 F Nucleoside 2-deoxyribosyltransferase
HFLFIKEJ_00689 9.4e-253 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFLFIKEJ_00690 9.9e-58
HFLFIKEJ_00691 5.2e-292 frvR K Mga helix-turn-helix domain
HFLFIKEJ_00692 4.1e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
HFLFIKEJ_00693 1.4e-104 ygaC J Belongs to the UPF0374 family
HFLFIKEJ_00694 2.8e-96
HFLFIKEJ_00695 3.3e-74 S Acetyltransferase (GNAT) domain
HFLFIKEJ_00696 6.8e-207 yueF S AI-2E family transporter
HFLFIKEJ_00697 8.7e-243 hlyX S Transporter associated domain
HFLFIKEJ_00698 2.3e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFLFIKEJ_00699 4.3e-46 XK27_09445 S Domain of unknown function (DUF1827)
HFLFIKEJ_00700 0.0 clpE O Belongs to the ClpA ClpB family
HFLFIKEJ_00701 2e-28
HFLFIKEJ_00702 1.4e-38 ptsH G phosphocarrier protein HPR
HFLFIKEJ_00703 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFLFIKEJ_00704 1.2e-09 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFLFIKEJ_00705 1.8e-254 iolT EGP Major facilitator Superfamily
HFLFIKEJ_00707 1.6e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
HFLFIKEJ_00708 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFLFIKEJ_00709 5.1e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFLFIKEJ_00710 2.3e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HFLFIKEJ_00711 6.4e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFLFIKEJ_00712 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFLFIKEJ_00713 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFLFIKEJ_00714 9e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFLFIKEJ_00715 1.6e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HFLFIKEJ_00716 7.8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFLFIKEJ_00717 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HFLFIKEJ_00718 2e-217 purD 6.3.4.13 F Belongs to the GARS family
HFLFIKEJ_00719 1.6e-76 copR K Copper transport repressor CopY TcrY
HFLFIKEJ_00720 0.0 copB 3.6.3.4 P P-type ATPase
HFLFIKEJ_00721 3.2e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFLFIKEJ_00722 1.3e-207 T PhoQ Sensor
HFLFIKEJ_00723 1e-122 K response regulator
HFLFIKEJ_00724 6.3e-137 bceA V ABC transporter
HFLFIKEJ_00725 0.0 V ABC transporter (permease)
HFLFIKEJ_00726 7.6e-91 traP 1.14.99.57, 6.2.1.3 S Antibiotic biosynthesis monooxygenase
HFLFIKEJ_00727 2.5e-135 yhfI S Metallo-beta-lactamase superfamily
HFLFIKEJ_00728 1.5e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFLFIKEJ_00729 5.1e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFLFIKEJ_00730 1.4e-299 glpQ 3.1.4.46 C phosphodiesterase
HFLFIKEJ_00731 1.2e-177 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HFLFIKEJ_00732 3.9e-21
HFLFIKEJ_00733 1.2e-67
HFLFIKEJ_00735 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HFLFIKEJ_00736 5.3e-75 argR K Regulates arginine biosynthesis genes
HFLFIKEJ_00737 2.5e-155 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFLFIKEJ_00738 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HFLFIKEJ_00739 4.6e-55 yheA S Control of competence regulator ComK, YlbF/YmcA
HFLFIKEJ_00740 3.7e-182 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFLFIKEJ_00741 2.6e-158 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFLFIKEJ_00742 1.7e-47 yhaH S YtxH-like protein
HFLFIKEJ_00743 1.4e-72 hit FG histidine triad
HFLFIKEJ_00744 2.2e-131 ecsA V ABC transporter, ATP-binding protein
HFLFIKEJ_00745 5.3e-223 ecsB U ABC transporter
HFLFIKEJ_00746 1.2e-148 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HFLFIKEJ_00747 4.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFLFIKEJ_00749 4.7e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HFLFIKEJ_00750 3.2e-110 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFLFIKEJ_00752 1.3e-38 P Belongs to the nlpA lipoprotein family
HFLFIKEJ_00753 1.9e-95 P Belongs to the nlpA lipoprotein family
HFLFIKEJ_00754 4.2e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HFLFIKEJ_00755 1.2e-46 gcvH E glycine cleavage
HFLFIKEJ_00756 7.6e-222 rodA D Belongs to the SEDS family
HFLFIKEJ_00757 1.3e-31 S Protein of unknown function (DUF2969)
HFLFIKEJ_00758 1.6e-54 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HFLFIKEJ_00759 1.4e-25 epuA S DNA-directed RNA polymerase subunit beta
HFLFIKEJ_00760 4.5e-180 mbl D Cell shape determining protein MreB Mrl
HFLFIKEJ_00761 6.4e-32 ywzB S Protein of unknown function (DUF1146)
HFLFIKEJ_00762 1.6e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HFLFIKEJ_00763 1.2e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFLFIKEJ_00764 1.8e-08
HFLFIKEJ_00765 1.2e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFLFIKEJ_00766 2.8e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFLFIKEJ_00767 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFLFIKEJ_00768 2.6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFLFIKEJ_00769 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFLFIKEJ_00770 3.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HFLFIKEJ_00771 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFLFIKEJ_00772 2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFLFIKEJ_00773 1.2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFLFIKEJ_00774 3.6e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFLFIKEJ_00775 4.8e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFLFIKEJ_00776 6e-111 tdk 2.7.1.21 F thymidine kinase
HFLFIKEJ_00777 1e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HFLFIKEJ_00778 8.9e-192 ampC V Beta-lactamase
HFLFIKEJ_00779 2.3e-164 1.13.11.2 S glyoxalase
HFLFIKEJ_00780 2.5e-138 S NADPH-dependent FMN reductase
HFLFIKEJ_00781 0.0 yfiC V ABC transporter
HFLFIKEJ_00782 0.0 ycfI V ABC transporter, ATP-binding protein
HFLFIKEJ_00783 1.1e-121 K Bacterial regulatory proteins, tetR family
HFLFIKEJ_00784 1.5e-132 G Phosphoglycerate mutase family
HFLFIKEJ_00785 8.7e-09
HFLFIKEJ_00789 2.4e-283 pipD E Dipeptidase
HFLFIKEJ_00790 3.3e-193 yttB EGP Major facilitator Superfamily
HFLFIKEJ_00791 1.2e-17
HFLFIKEJ_00794 1.1e-210 L PFAM transposase, IS4 family protein
HFLFIKEJ_00800 5.8e-85 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
HFLFIKEJ_00801 1.7e-173 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HFLFIKEJ_00802 3e-231 wbbX GT2,GT4 M Glycosyl transferases group 1
HFLFIKEJ_00803 4.1e-77 yttA 2.7.13.3 S Pfam Transposase IS66
HFLFIKEJ_00804 1.4e-113 F DNA/RNA non-specific endonuclease
HFLFIKEJ_00805 3.3e-46 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HFLFIKEJ_00810 1.1e-217 M Glycosyl hydrolases family 25
HFLFIKEJ_00811 6.2e-44 hol S Bacteriophage holin
HFLFIKEJ_00812 1e-45
HFLFIKEJ_00814 2.1e-24
HFLFIKEJ_00815 5.2e-234 S peptidoglycan catabolic process
HFLFIKEJ_00816 7.3e-161 S Phage tail protein
HFLFIKEJ_00817 1.5e-285 S phage tail tape measure protein
HFLFIKEJ_00818 2.3e-37
HFLFIKEJ_00819 2.1e-49 S Phage tail assembly chaperone protein, TAC
HFLFIKEJ_00820 1.2e-103 S Phage tail tube protein
HFLFIKEJ_00821 1.6e-67 S Protein of unknown function (DUF3168)
HFLFIKEJ_00822 1.1e-49 S Bacteriophage HK97-gp10, putative tail-component
HFLFIKEJ_00823 5.7e-49
HFLFIKEJ_00824 9.4e-62 S Phage gp6-like head-tail connector protein
HFLFIKEJ_00825 2.4e-184 gpG
HFLFIKEJ_00826 3.3e-94 S Domain of unknown function (DUF4355)
HFLFIKEJ_00827 5.5e-178 S head morphogenesis protein, SPP1 gp7 family
HFLFIKEJ_00828 1.1e-251 S Phage portal protein
HFLFIKEJ_00829 2.4e-247 S Terminase-like family
HFLFIKEJ_00830 9.8e-27 S Helix-turn-helix of insertion element transposase
HFLFIKEJ_00831 7e-31
HFLFIKEJ_00832 1.7e-90
HFLFIKEJ_00833 9.1e-77
HFLFIKEJ_00838 2.5e-11
HFLFIKEJ_00839 1.1e-26
HFLFIKEJ_00841 7.6e-39
HFLFIKEJ_00842 2.9e-49
HFLFIKEJ_00843 2e-08 K Cro/C1-type HTH DNA-binding domain
HFLFIKEJ_00844 6.6e-63 S Hypothetical protein (DUF2513)
HFLFIKEJ_00846 7.4e-135 L Replication initiation and membrane attachment
HFLFIKEJ_00847 5e-133 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HFLFIKEJ_00848 1.9e-153 recT L RecT family
HFLFIKEJ_00851 1.7e-15
HFLFIKEJ_00853 4.8e-99
HFLFIKEJ_00855 6.8e-10 S Domain of unknown function (DUF1508)
HFLFIKEJ_00859 5.3e-55 3.4.21.88 KT Peptidase S24-like
HFLFIKEJ_00860 2.6e-14
HFLFIKEJ_00861 3.5e-57 S Domain of unknown function (DUF5067)
HFLFIKEJ_00862 1.2e-60 S Pyridoxamine 5'-phosphate oxidase
HFLFIKEJ_00863 2e-29
HFLFIKEJ_00864 1.8e-11
HFLFIKEJ_00866 4.2e-225 L Pfam:Integrase_AP2
HFLFIKEJ_00867 2.2e-274 nisT V ABC transporter
HFLFIKEJ_00869 2.3e-116 S Acetyltransferase (GNAT) family
HFLFIKEJ_00870 3.2e-292 E ABC transporter, substratebinding protein
HFLFIKEJ_00871 3.6e-235 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HFLFIKEJ_00872 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLFIKEJ_00873 3.8e-193 ypdE E M42 glutamyl aminopeptidase
HFLFIKEJ_00874 4.2e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFLFIKEJ_00875 6.7e-59 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_00876 2.7e-252 2.7.1.207 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLFIKEJ_00877 1.2e-181 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFLFIKEJ_00878 2.3e-226 4.4.1.8 E Aminotransferase, class I
HFLFIKEJ_00879 6.8e-205 S Uncharacterized protein conserved in bacteria (DUF2325)
HFLFIKEJ_00880 0.0 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HFLFIKEJ_00881 2.9e-295 2.4.1.52 GT4 M Glycosyl transferases group 1
HFLFIKEJ_00882 7.8e-64 XK27_08465 2.7.1.191 G PTS system fructose IIA component
HFLFIKEJ_00883 3e-145 manZ_1 G PTS system mannose/fructose/sorbose family IID component
HFLFIKEJ_00884 1.5e-140 XK27_08455 G PTS system sorbose-specific iic component
HFLFIKEJ_00885 8.1e-82 manX_1 2.7.1.191 G PTS system sorbose subfamily IIB component
HFLFIKEJ_00886 0.0 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
HFLFIKEJ_00887 2.1e-224 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFLFIKEJ_00888 1.3e-218 agaS G SIS domain
HFLFIKEJ_00889 9e-130 XK27_08435 K UTRA
HFLFIKEJ_00890 3.7e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
HFLFIKEJ_00891 1.7e-82
HFLFIKEJ_00892 1.6e-238 malE G Bacterial extracellular solute-binding protein
HFLFIKEJ_00893 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HFLFIKEJ_00894 1.8e-119
HFLFIKEJ_00895 1.2e-157 sepS16B
HFLFIKEJ_00896 2.4e-235 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HFLFIKEJ_00897 5.2e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HFLFIKEJ_00898 2.1e-144 K CAT RNA binding domain
HFLFIKEJ_00899 1.6e-260 lacE-1 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HFLFIKEJ_00900 4.7e-260 nox 1.6.3.4 C NADH oxidase
HFLFIKEJ_00901 1.7e-143 p75 M NlpC P60 family protein
HFLFIKEJ_00902 1.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HFLFIKEJ_00903 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HFLFIKEJ_00904 1.1e-115 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFLFIKEJ_00906 5e-221 yceI G Sugar (and other) transporter
HFLFIKEJ_00907 3.7e-88
HFLFIKEJ_00908 1e-153 K acetyltransferase
HFLFIKEJ_00909 1.3e-224 mdtG EGP Major facilitator Superfamily
HFLFIKEJ_00910 7.7e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFLFIKEJ_00911 3.8e-55 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFLFIKEJ_00912 6e-155 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFLFIKEJ_00913 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
HFLFIKEJ_00914 7.3e-172 ccpB 5.1.1.1 K lacI family
HFLFIKEJ_00915 1.7e-67
HFLFIKEJ_00916 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFLFIKEJ_00917 9e-107 rsmC 2.1.1.172 J Methyltransferase
HFLFIKEJ_00918 1.2e-49
HFLFIKEJ_00919 9.8e-86 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFLFIKEJ_00920 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFLFIKEJ_00921 1.5e-33 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFLFIKEJ_00922 5.6e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFLFIKEJ_00923 8.7e-38 S Protein of unknown function (DUF2508)
HFLFIKEJ_00924 7.4e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFLFIKEJ_00925 7.8e-52 yaaQ S Cyclic-di-AMP receptor
HFLFIKEJ_00926 4.3e-175 holB 2.7.7.7 L DNA polymerase III
HFLFIKEJ_00927 1.7e-57 yabA L Involved in initiation control of chromosome replication
HFLFIKEJ_00928 1.6e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFLFIKEJ_00929 1.1e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
HFLFIKEJ_00930 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
HFLFIKEJ_00931 7.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HFLFIKEJ_00932 1.2e-118
HFLFIKEJ_00933 1.6e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HFLFIKEJ_00934 1.4e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HFLFIKEJ_00935 1.8e-187 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFLFIKEJ_00936 1.6e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_00937 0.0 uup S ABC transporter, ATP-binding protein
HFLFIKEJ_00938 4.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFLFIKEJ_00939 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HFLFIKEJ_00940 2.3e-159 ytrB V ABC transporter
HFLFIKEJ_00941 6e-194
HFLFIKEJ_00942 3.7e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFLFIKEJ_00943 4.2e-110 ydiL S CAAX protease self-immunity
HFLFIKEJ_00944 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFLFIKEJ_00945 4.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFLFIKEJ_00946 1.9e-56 S Domain of unknown function (DUF1827)
HFLFIKEJ_00947 0.0 ydaO E amino acid
HFLFIKEJ_00948 1.9e-145 L Transposase and inactivated derivatives IS30 family
HFLFIKEJ_00949 1.5e-31 L Transposase and inactivated derivatives IS30 family
HFLFIKEJ_00950 3.4e-139 M Psort location Cytoplasmic, score 8.87
HFLFIKEJ_00951 6.6e-52 GT4 M Psort location Cytoplasmic, score 8.87
HFLFIKEJ_00952 1.2e-07
HFLFIKEJ_00953 8.9e-63 C Polysaccharide pyruvyl transferase
HFLFIKEJ_00954 2.9e-119 S Psort location CytoplasmicMembrane, score 9.99
HFLFIKEJ_00955 1.3e-46 M Glycosyltransferase like family 2
HFLFIKEJ_00956 7.7e-178 menD 2.2.1.9 H Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
HFLFIKEJ_00957 2e-135 stp 3.1.3.16 T phosphatase
HFLFIKEJ_00958 8.7e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFLFIKEJ_00959 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFLFIKEJ_00960 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFLFIKEJ_00961 8.1e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFLFIKEJ_00962 2.9e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFLFIKEJ_00963 3.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HFLFIKEJ_00964 1.6e-120 rssA S Patatin-like phospholipase
HFLFIKEJ_00965 3e-50
HFLFIKEJ_00966 1.7e-307 recN L May be involved in recombinational repair of damaged DNA
HFLFIKEJ_00967 2e-74 argR K Regulates arginine biosynthesis genes
HFLFIKEJ_00968 3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HFLFIKEJ_00969 9.7e-147 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFLFIKEJ_00970 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFLFIKEJ_00971 1.1e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFLFIKEJ_00972 5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFLFIKEJ_00973 2e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFLFIKEJ_00974 1.5e-72 yqhY S Asp23 family, cell envelope-related function
HFLFIKEJ_00975 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFLFIKEJ_00976 7e-203 ypdF 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFLFIKEJ_00977 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HFLFIKEJ_00978 1e-54 ysxB J Cysteine protease Prp
HFLFIKEJ_00979 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HFLFIKEJ_00980 1.3e-32
HFLFIKEJ_00981 4.1e-14
HFLFIKEJ_00982 7.4e-233 ywhK S Membrane
HFLFIKEJ_00984 6.4e-264 V ABC transporter transmembrane region
HFLFIKEJ_00985 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFLFIKEJ_00986 5.8e-263 glnA 6.3.1.2 E glutamine synthetase
HFLFIKEJ_00987 1e-60 glnR K Transcriptional regulator
HFLFIKEJ_00988 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HFLFIKEJ_00989 5.9e-241 ynbB 4.4.1.1 P aluminum resistance
HFLFIKEJ_00990 5.7e-180 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFLFIKEJ_00991 9.8e-25 WQ51_02665 S Protein of unknown function (DUF3042)
HFLFIKEJ_00992 3.7e-72 yqhL P Rhodanese-like protein
HFLFIKEJ_00993 2e-177 glk 2.7.1.2 G Glucokinase
HFLFIKEJ_00994 1.1e-40 yqgQ S Bacterial protein of unknown function (DUF910)
HFLFIKEJ_00995 9.6e-121 gluP 3.4.21.105 S Peptidase, S54 family
HFLFIKEJ_00996 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HFLFIKEJ_00997 0.0 S Bacterial membrane protein YfhO
HFLFIKEJ_00998 3.7e-53 yneR S Belongs to the HesB IscA family
HFLFIKEJ_00999 5.8e-115 vraR K helix_turn_helix, Lux Regulon
HFLFIKEJ_01000 3e-182 vraS 2.7.13.3 T Histidine kinase
HFLFIKEJ_01001 2.3e-122 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HFLFIKEJ_01002 4.1e-09
HFLFIKEJ_01003 8.2e-128 K cheY-homologous receiver domain
HFLFIKEJ_01004 2.5e-239 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HFLFIKEJ_01005 2.4e-67 yqkB S Belongs to the HesB IscA family
HFLFIKEJ_01006 1.7e-122 drgA C Nitroreductase family
HFLFIKEJ_01007 4.1e-206 lctO C IMP dehydrogenase / GMP reductase domain
HFLFIKEJ_01010 1.9e-181 K sequence-specific DNA binding
HFLFIKEJ_01011 7e-56 K Transcriptional regulator PadR-like family
HFLFIKEJ_01012 4e-42 ygbF S Sugar efflux transporter for intercellular exchange
HFLFIKEJ_01013 6.6e-50
HFLFIKEJ_01014 3.4e-186 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HFLFIKEJ_01015 2.2e-55
HFLFIKEJ_01016 3.4e-80
HFLFIKEJ_01017 2.3e-207 yubA S AI-2E family transporter
HFLFIKEJ_01018 7.4e-26
HFLFIKEJ_01019 1e-97 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFLFIKEJ_01020 3.6e-74
HFLFIKEJ_01021 2.9e-168 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HFLFIKEJ_01022 2.3e-105 ywrF S Flavin reductase like domain
HFLFIKEJ_01023 3.3e-95
HFLFIKEJ_01024 2.3e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFLFIKEJ_01025 1.8e-59 yeaO S Protein of unknown function, DUF488
HFLFIKEJ_01026 1.9e-172 corA P CorA-like Mg2+ transporter protein
HFLFIKEJ_01027 4.6e-160 mleR K LysR family
HFLFIKEJ_01028 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HFLFIKEJ_01029 1.1e-170 mleP S Sodium Bile acid symporter family
HFLFIKEJ_01030 2.7e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HFLFIKEJ_01031 3.1e-95
HFLFIKEJ_01032 1.7e-171 K sequence-specific DNA binding
HFLFIKEJ_01033 3.5e-267 V ABC transporter transmembrane region
HFLFIKEJ_01034 0.0 pepF E Oligopeptidase F
HFLFIKEJ_01035 5e-78 ndk 2.7.4.6 F Belongs to the NDK family
HFLFIKEJ_01036 7e-59
HFLFIKEJ_01037 0.0 yfgQ P E1-E2 ATPase
HFLFIKEJ_01038 2.6e-177 3.4.11.5 I Releases the N-terminal proline from various substrates
HFLFIKEJ_01039 1.8e-59
HFLFIKEJ_01040 1.5e-93 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HFLFIKEJ_01041 1.9e-193 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFLFIKEJ_01042 1.6e-120 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
HFLFIKEJ_01043 1.5e-77 K Transcriptional regulator
HFLFIKEJ_01044 4.7e-179 D Alpha beta
HFLFIKEJ_01045 1.1e-83 nrdI F Belongs to the NrdI family
HFLFIKEJ_01046 4.5e-157 dkgB S reductase
HFLFIKEJ_01047 1.1e-117
HFLFIKEJ_01048 1.7e-159 S Alpha beta hydrolase
HFLFIKEJ_01049 1e-116 yviA S Protein of unknown function (DUF421)
HFLFIKEJ_01050 3.5e-74 S Protein of unknown function (DUF3290)
HFLFIKEJ_01051 1.6e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HFLFIKEJ_01052 1e-295 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HFLFIKEJ_01053 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HFLFIKEJ_01054 3.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFLFIKEJ_01055 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFLFIKEJ_01056 5.4e-138 est 3.1.1.1 S Serine aminopeptidase, S33
HFLFIKEJ_01057 9.3e-31 secG U Preprotein translocase
HFLFIKEJ_01058 1.7e-60
HFLFIKEJ_01059 7e-292 clcA P chloride
HFLFIKEJ_01060 6e-186 tas C Aldo/keto reductase family
HFLFIKEJ_01061 1.8e-44 S Enterocin A Immunity
HFLFIKEJ_01062 1.8e-136
HFLFIKEJ_01063 2.3e-134
HFLFIKEJ_01064 1.4e-56 K Transcriptional regulator PadR-like family
HFLFIKEJ_01065 4.1e-97 K Helix-turn-helix XRE-family like proteins
HFLFIKEJ_01066 1.8e-206 MA20_36090 S Protein of unknown function (DUF2974)
HFLFIKEJ_01067 1.5e-222 N Uncharacterized conserved protein (DUF2075)
HFLFIKEJ_01068 4e-54 S CAAX protease self-immunity
HFLFIKEJ_01069 2.8e-102
HFLFIKEJ_01070 0.0 M domain protein
HFLFIKEJ_01071 8.4e-262 M domain protein
HFLFIKEJ_01072 3.1e-292 M Cna protein B-type domain
HFLFIKEJ_01073 1.4e-134 3.4.22.70 M Sortase family
HFLFIKEJ_01076 5.2e-55 V ABC transporter
HFLFIKEJ_01077 7.5e-33 bacI V MacB-like periplasmic core domain
HFLFIKEJ_01078 5.3e-90
HFLFIKEJ_01080 5.4e-150 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFLFIKEJ_01081 1.6e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFLFIKEJ_01082 4.9e-224 pimH EGP Major facilitator Superfamily
HFLFIKEJ_01083 7.4e-34
HFLFIKEJ_01084 2.5e-32
HFLFIKEJ_01085 5.4e-08
HFLFIKEJ_01087 8.8e-09 yhjA S CsbD-like
HFLFIKEJ_01088 9.6e-195 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HFLFIKEJ_01089 7.2e-46
HFLFIKEJ_01090 1.5e-200 ltrA S Bacterial low temperature requirement A protein (LtrA)
HFLFIKEJ_01091 2.9e-122 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFLFIKEJ_01092 1.5e-92 ccpN K Domain in cystathionine beta-synthase and other proteins.
HFLFIKEJ_01093 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
HFLFIKEJ_01094 0.0 kup P Transport of potassium into the cell
HFLFIKEJ_01095 7.3e-166 V ATPases associated with a variety of cellular activities
HFLFIKEJ_01096 7.3e-209 S ABC-2 family transporter protein
HFLFIKEJ_01097 7.7e-197
HFLFIKEJ_01098 1.4e-261 pepC 3.4.22.40 E Peptidase C1-like family
HFLFIKEJ_01099 8.8e-256 pepC 3.4.22.40 E aminopeptidase
HFLFIKEJ_01100 1.7e-43 trxC O Belongs to the thioredoxin family
HFLFIKEJ_01101 5.6e-133 thrE S Putative threonine/serine exporter
HFLFIKEJ_01102 3.5e-74 S Threonine/Serine exporter, ThrE
HFLFIKEJ_01103 1.4e-212 livJ E Receptor family ligand binding region
HFLFIKEJ_01104 1.5e-150 livH U Branched-chain amino acid transport system / permease component
HFLFIKEJ_01105 1.7e-120 livM E Branched-chain amino acid transport system / permease component
HFLFIKEJ_01106 3.6e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
HFLFIKEJ_01107 1.8e-122 livF E ABC transporter
HFLFIKEJ_01108 1.2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HFLFIKEJ_01109 1.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HFLFIKEJ_01110 5.2e-232 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLFIKEJ_01111 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFLFIKEJ_01112 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFLFIKEJ_01113 6.1e-258 glnPH2 P ABC transporter permease
HFLFIKEJ_01114 2.3e-20
HFLFIKEJ_01115 2.3e-47 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HFLFIKEJ_01116 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HFLFIKEJ_01117 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFLFIKEJ_01118 6.1e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFLFIKEJ_01119 0.0 yknV V ABC transporter
HFLFIKEJ_01120 9.3e-65 rmeD K helix_turn_helix, mercury resistance
HFLFIKEJ_01121 1.7e-63 pcaC 4.1.1.44 S Carboxymuconolactone decarboxylase family
HFLFIKEJ_01122 4.8e-134 cobB K Sir2 family
HFLFIKEJ_01123 1.7e-82 M Protein of unknown function (DUF3737)
HFLFIKEJ_01124 1.2e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFLFIKEJ_01125 1.6e-160 S Tetratricopeptide repeat
HFLFIKEJ_01126 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFLFIKEJ_01127 1.5e-126
HFLFIKEJ_01128 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFLFIKEJ_01129 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
HFLFIKEJ_01130 2.2e-193 holA 2.7.7.7 L DNA polymerase III delta subunit
HFLFIKEJ_01131 0.0 comEC S Competence protein ComEC
HFLFIKEJ_01132 4.2e-105 comEA L Competence protein ComEA
HFLFIKEJ_01133 7.9e-194 ylbL T Belongs to the peptidase S16 family
HFLFIKEJ_01134 4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFLFIKEJ_01135 1.7e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HFLFIKEJ_01136 2.5e-56 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HFLFIKEJ_01137 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HFLFIKEJ_01138 6.5e-210 ftsW D Belongs to the SEDS family
HFLFIKEJ_01139 0.0 typA T GTP-binding protein TypA
HFLFIKEJ_01140 5e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HFLFIKEJ_01141 3.2e-46 yktA S Belongs to the UPF0223 family
HFLFIKEJ_01142 8.3e-157 1.1.1.27 C L-malate dehydrogenase activity
HFLFIKEJ_01143 2.4e-259 lpdA 1.8.1.4 C Dehydrogenase
HFLFIKEJ_01144 3.1e-242 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFLFIKEJ_01145 1.8e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HFLFIKEJ_01146 1.1e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HFLFIKEJ_01147 2.1e-135 S E1-E2 ATPase
HFLFIKEJ_01148 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFLFIKEJ_01149 2.5e-25
HFLFIKEJ_01150 2.4e-72
HFLFIKEJ_01152 3.8e-69 S SdpI/YhfL protein family
HFLFIKEJ_01153 3.1e-133 K response regulator
HFLFIKEJ_01154 4.6e-272 yclK 2.7.13.3 T Histidine kinase
HFLFIKEJ_01155 1.3e-93 yhbS S acetyltransferase
HFLFIKEJ_01156 7.6e-31
HFLFIKEJ_01157 5.2e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
HFLFIKEJ_01158 3.8e-82
HFLFIKEJ_01159 5.3e-59
HFLFIKEJ_01160 5.5e-250 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HFLFIKEJ_01162 8.1e-176 S response to antibiotic
HFLFIKEJ_01163 6.4e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
HFLFIKEJ_01164 9e-184 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFLFIKEJ_01165 5.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFLFIKEJ_01166 6.6e-63
HFLFIKEJ_01167 1.2e-49 K sequence-specific DNA binding
HFLFIKEJ_01168 2.5e-71 3.6.1.55 L NUDIX domain
HFLFIKEJ_01169 1.5e-150 EG EamA-like transporter family
HFLFIKEJ_01171 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HFLFIKEJ_01172 5.1e-70 rplI J Binds to the 23S rRNA
HFLFIKEJ_01173 1.7e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HFLFIKEJ_01174 4e-220
HFLFIKEJ_01175 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFLFIKEJ_01176 2.2e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HFLFIKEJ_01177 1.1e-197 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HFLFIKEJ_01178 1.8e-156 K Helix-turn-helix domain, rpiR family
HFLFIKEJ_01179 9.1e-107 K Transcriptional regulator C-terminal region
HFLFIKEJ_01180 2.7e-126 V ABC transporter, ATP-binding protein
HFLFIKEJ_01181 0.0 ylbB V ABC transporter permease
HFLFIKEJ_01182 2.5e-205 4.1.1.52 S Amidohydrolase
HFLFIKEJ_01183 4.9e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFLFIKEJ_01184 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HFLFIKEJ_01185 6e-55 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HFLFIKEJ_01186 9.1e-153 K Helix-turn-helix XRE-family like proteins
HFLFIKEJ_01187 9.7e-27 S Phospholipase_D-nuclease N-terminal
HFLFIKEJ_01188 4e-34 yxlF V ABC transporter
HFLFIKEJ_01189 3.3e-66 yxlF V ABC transporter
HFLFIKEJ_01190 2e-103 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HFLFIKEJ_01191 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HFLFIKEJ_01192 1e-122
HFLFIKEJ_01193 1.4e-181 yveB 2.7.4.29 I PAP2 superfamily
HFLFIKEJ_01194 1.8e-206 mccF V LD-carboxypeptidase
HFLFIKEJ_01196 2.5e-42
HFLFIKEJ_01197 2.4e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HFLFIKEJ_01198 1.1e-40
HFLFIKEJ_01200 1.2e-74
HFLFIKEJ_01202 1.7e-51 sugE U Multidrug resistance protein
HFLFIKEJ_01203 9.7e-143 Q Methyltransferase
HFLFIKEJ_01204 4.2e-74 adhR K helix_turn_helix, mercury resistance
HFLFIKEJ_01205 4.2e-158 1.1.1.346 S reductase
HFLFIKEJ_01206 2.1e-171 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HFLFIKEJ_01207 2.8e-199 S endonuclease exonuclease phosphatase family protein
HFLFIKEJ_01209 1.8e-129 G PTS system sorbose-specific iic component
HFLFIKEJ_01210 5.4e-150 G PTS system mannose/fructose/sorbose family IID component
HFLFIKEJ_01211 5.8e-80 2.7.1.191 G PTS system sorbose subfamily IIB component
HFLFIKEJ_01212 3.4e-161 ybbH_2 K Helix-turn-helix domain, rpiR family
HFLFIKEJ_01213 1.7e-146 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HFLFIKEJ_01214 1.7e-190 blaA6 V Beta-lactamase
HFLFIKEJ_01215 1.4e-147 3.5.2.6 V Beta-lactamase enzyme family
HFLFIKEJ_01216 5.4e-226 EGP Major facilitator Superfamily
HFLFIKEJ_01217 2.8e-210 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HFLFIKEJ_01218 2.8e-163 ugpA P ABC-type sugar transport systems, permease components
HFLFIKEJ_01219 6.4e-148 ugpE G ABC transporter permease
HFLFIKEJ_01220 3.2e-240 ugpB G Bacterial extracellular solute-binding protein
HFLFIKEJ_01221 3.3e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFLFIKEJ_01222 3.6e-131 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HFLFIKEJ_01223 9.5e-264 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFLFIKEJ_01224 4.5e-108 pncA Q Isochorismatase family
HFLFIKEJ_01225 9.6e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
HFLFIKEJ_01226 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
HFLFIKEJ_01227 5.2e-96 K Helix-turn-helix domain
HFLFIKEJ_01229 3.4e-112 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HFLFIKEJ_01230 2e-91 yjgM K Acetyltransferase (GNAT) domain
HFLFIKEJ_01231 2.4e-133 farR K Helix-turn-helix domain
HFLFIKEJ_01232 6.9e-161 gatY G Fructose-bisphosphate aldolase class-II
HFLFIKEJ_01233 4.2e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLFIKEJ_01234 1.6e-48 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_01235 4.7e-252 gatC G PTS system sugar-specific permease component
HFLFIKEJ_01236 5.7e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HFLFIKEJ_01237 3.7e-162 G Fructose-bisphosphate aldolase class-II
HFLFIKEJ_01238 2.6e-245 licR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLFIKEJ_01239 2.3e-69 ahaA 2.7.1.191 G PTS system fructose IIA component
HFLFIKEJ_01240 8.5e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
HFLFIKEJ_01241 3.7e-137 G PTS system sorbose-specific iic component
HFLFIKEJ_01242 1.3e-151 manZ G PTS system mannose/fructose/sorbose family IID component
HFLFIKEJ_01243 1.2e-204 C Zinc-binding dehydrogenase
HFLFIKEJ_01244 4e-278 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HFLFIKEJ_01245 1.9e-95 S Domain of unknown function (DUF4428)
HFLFIKEJ_01246 1.7e-206 3.2.1.51 GH29 G Alpha-L-fucosidase
HFLFIKEJ_01247 5.3e-215 uhpT EGP Major facilitator Superfamily
HFLFIKEJ_01248 3.5e-129 ymfC K UTRA
HFLFIKEJ_01249 9.1e-253 3.5.1.18 E Peptidase family M20/M25/M40
HFLFIKEJ_01250 1.7e-179 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HFLFIKEJ_01251 6.6e-154 bglK_1 GK ROK family
HFLFIKEJ_01252 4.5e-42
HFLFIKEJ_01253 0.0 O Belongs to the peptidase S8 family
HFLFIKEJ_01254 3.4e-213 ulaG S Beta-lactamase superfamily domain
HFLFIKEJ_01255 1.1e-80 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLFIKEJ_01256 5.3e-281 ulaA S PTS system sugar-specific permease component
HFLFIKEJ_01257 3.7e-45 sgaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_01258 7.4e-115 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HFLFIKEJ_01259 2.2e-137 repA K DeoR C terminal sensor domain
HFLFIKEJ_01260 3.6e-168 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HFLFIKEJ_01261 4.1e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HFLFIKEJ_01262 1e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HFLFIKEJ_01263 2.2e-145 IQ NAD dependent epimerase/dehydratase family
HFLFIKEJ_01264 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HFLFIKEJ_01265 1.8e-87 gutM K Glucitol operon activator protein (GutM)
HFLFIKEJ_01266 2.2e-102 srlA G PTS system enzyme II sorbitol-specific factor
HFLFIKEJ_01267 1.6e-194 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HFLFIKEJ_01268 6.7e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HFLFIKEJ_01269 1.3e-122 tal 2.2.1.2 H Pfam:Transaldolase
HFLFIKEJ_01270 0.0 K Mga helix-turn-helix domain
HFLFIKEJ_01271 6.9e-54 S PRD domain
HFLFIKEJ_01272 3.4e-61 S Glycine-rich SFCGS
HFLFIKEJ_01273 6e-53 S Domain of unknown function (DUF4312)
HFLFIKEJ_01274 8.3e-137 S Domain of unknown function (DUF4311)
HFLFIKEJ_01275 1e-106 S Domain of unknown function (DUF4310)
HFLFIKEJ_01276 4.4e-216 dho 3.5.2.3 S Amidohydrolase family
HFLFIKEJ_01277 4.2e-203 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
HFLFIKEJ_01278 1.8e-136 4.1.2.14 S KDGP aldolase
HFLFIKEJ_01287 1.3e-22
HFLFIKEJ_01290 1.6e-31
HFLFIKEJ_01291 4.5e-31 S D12 class N6 adenine-specific DNA methyltransferase
HFLFIKEJ_01292 4.9e-32
HFLFIKEJ_01302 5.7e-33 S Terminase RNAseH like domain
HFLFIKEJ_01306 5.9e-77 res L helicase
HFLFIKEJ_01310 5.4e-86 S Phage plasmid primase, P4 family
HFLFIKEJ_01312 6.9e-47 S AAA domain
HFLFIKEJ_01313 2.1e-51
HFLFIKEJ_01317 1.9e-11 S hydrolase activity, acting on ester bonds
HFLFIKEJ_01334 2e-135 ksgA 2.1.1.182, 2.1.1.197, 2.5.1.134 J rRNA (adenine-N6,N6-)-dimethyltransferase activity
HFLFIKEJ_01335 8.9e-292 S ABC transporter
HFLFIKEJ_01336 2.7e-174 draG O ADP-ribosylglycohydrolase
HFLFIKEJ_01337 1.8e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HFLFIKEJ_01338 2.2e-52
HFLFIKEJ_01339 1.8e-133 XK27_06755 S Protein of unknown function (DUF975)
HFLFIKEJ_01340 2.6e-146 M Glycosyltransferase like family 2
HFLFIKEJ_01341 2.2e-134 glcR K DeoR C terminal sensor domain
HFLFIKEJ_01342 1.5e-09 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFLFIKEJ_01343 1.1e-71 T Sh3 type 3 domain protein
HFLFIKEJ_01344 1.5e-245 brnQ U Component of the transport system for branched-chain amino acids
HFLFIKEJ_01345 5.7e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFLFIKEJ_01346 0.0 pepF E oligoendopeptidase F
HFLFIKEJ_01347 1.9e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HFLFIKEJ_01348 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
HFLFIKEJ_01349 3e-134 znuB U ABC 3 transport family
HFLFIKEJ_01350 4.1e-130 fhuC 3.6.3.35 P ABC transporter
HFLFIKEJ_01351 7.6e-58
HFLFIKEJ_01352 2.8e-204 gntP EG Gluconate
HFLFIKEJ_01353 1.5e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HFLFIKEJ_01354 4.4e-167 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HFLFIKEJ_01355 2.1e-146 gntR K rpiR family
HFLFIKEJ_01356 1.3e-170 iolH G Xylose isomerase-like TIM barrel
HFLFIKEJ_01357 3.9e-131 iolI 5.3.99.11 G Xylose isomerase-like TIM barrel
HFLFIKEJ_01358 1.1e-65 iolK S Tautomerase enzyme
HFLFIKEJ_01359 9.6e-158 iolJ 4.1.2.13, 4.1.2.29 G Fructose-bisphosphate aldolase class-II
HFLFIKEJ_01360 1.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HFLFIKEJ_01361 1.8e-195 iolG2 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HFLFIKEJ_01362 3.2e-192 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HFLFIKEJ_01363 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HFLFIKEJ_01364 1.4e-178 iolC 2.7.1.92 H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HFLFIKEJ_01365 8.4e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HFLFIKEJ_01366 9.5e-275 iolA 1.2.1.18, 1.2.1.27 C Belongs to the aldehyde dehydrogenase family
HFLFIKEJ_01367 1.5e-267 iolT EGP Major facilitator Superfamily
HFLFIKEJ_01368 1.6e-140 iolR K DeoR C terminal sensor domain
HFLFIKEJ_01369 8e-128 yvgN C Aldo keto reductase
HFLFIKEJ_01370 1.1e-171 M Peptidoglycan-binding domain 1 protein
HFLFIKEJ_01371 1.9e-74 ynhH S NusG domain II
HFLFIKEJ_01372 2.8e-310 cydD CO ABC transporter transmembrane region
HFLFIKEJ_01373 6.7e-282 cydC V ABC transporter transmembrane region
HFLFIKEJ_01374 3.9e-159 licT K CAT RNA binding domain
HFLFIKEJ_01375 0.0 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFLFIKEJ_01376 2.3e-257 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFLFIKEJ_01377 2e-146 IQ reductase
HFLFIKEJ_01378 4.8e-114 VPA0052 I ABC-2 family transporter protein
HFLFIKEJ_01379 1.3e-162 CcmA V ABC transporter
HFLFIKEJ_01380 1.4e-63 K helix_turn_helix gluconate operon transcriptional repressor
HFLFIKEJ_01381 3.5e-209 ysdA CP ABC-2 family transporter protein
HFLFIKEJ_01382 2.6e-166 natA S ABC transporter
HFLFIKEJ_01383 2.6e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFLFIKEJ_01384 5.2e-173 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFLFIKEJ_01385 4.3e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HFLFIKEJ_01386 1.7e-204 S Calcineurin-like phosphoesterase
HFLFIKEJ_01387 0.0 asnB 6.3.5.4 E Asparagine synthase
HFLFIKEJ_01388 1.5e-169 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFLFIKEJ_01389 4.7e-173 XK27_06930 V domain protein
HFLFIKEJ_01390 2.3e-102 K Bacterial regulatory proteins, tetR family
HFLFIKEJ_01391 2.4e-144 S Alpha/beta hydrolase family
HFLFIKEJ_01392 2.1e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
HFLFIKEJ_01393 2.1e-216 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HFLFIKEJ_01394 1.6e-177 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLFIKEJ_01395 1.2e-154 pfoS S Phosphotransferase system, EIIC
HFLFIKEJ_01396 9.7e-68
HFLFIKEJ_01397 4.7e-168 yqiK S SPFH domain / Band 7 family
HFLFIKEJ_01398 1.6e-249 yclM 2.7.2.4 E Belongs to the aspartokinase family
HFLFIKEJ_01399 2e-230 hom 1.1.1.3 E homoserine dehydrogenase
HFLFIKEJ_01400 4.4e-283 thrC 4.2.3.1 E Threonine synthase
HFLFIKEJ_01401 1.2e-155 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFLFIKEJ_01402 1.9e-80 fld C Flavodoxin
HFLFIKEJ_01403 7.3e-178 yihY S Belongs to the UPF0761 family
HFLFIKEJ_01404 1.4e-259 S Uncharacterized protein conserved in bacteria (DUF2252)
HFLFIKEJ_01405 2.7e-111 K Bacterial regulatory proteins, tetR family
HFLFIKEJ_01406 2.4e-239 pepS E Thermophilic metalloprotease (M29)
HFLFIKEJ_01408 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HFLFIKEJ_01409 5.7e-07
HFLFIKEJ_01411 1.9e-71 S Domain of unknown function (DUF3284)
HFLFIKEJ_01412 1.5e-47 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFLFIKEJ_01413 4.5e-236 yfmL 3.6.4.13 L DEAD DEAH box helicase
HFLFIKEJ_01414 1.7e-177 mocA S Oxidoreductase
HFLFIKEJ_01415 2e-61 S Domain of unknown function (DUF4828)
HFLFIKEJ_01416 1.1e-59 S Protein of unknown function (DUF1093)
HFLFIKEJ_01417 7.5e-132 lys M Glycosyl hydrolases family 25
HFLFIKEJ_01418 3.2e-29
HFLFIKEJ_01419 5e-120 qmcA O prohibitin homologues
HFLFIKEJ_01420 6.8e-164 degV S Uncharacterised protein, DegV family COG1307
HFLFIKEJ_01421 3.7e-76 K Acetyltransferase (GNAT) domain
HFLFIKEJ_01422 0.0 pepO 3.4.24.71 O Peptidase family M13
HFLFIKEJ_01423 2e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HFLFIKEJ_01424 3.9e-145 cof S Sucrose-6F-phosphate phosphohydrolase
HFLFIKEJ_01425 1.2e-216 yttB EGP Major facilitator Superfamily
HFLFIKEJ_01426 2.4e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFLFIKEJ_01427 2.9e-193 yegS 2.7.1.107 G Lipid kinase
HFLFIKEJ_01428 6.1e-279 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFLFIKEJ_01429 3.3e-264 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFLFIKEJ_01430 4.9e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFLFIKEJ_01431 1.2e-203 camS S sex pheromone
HFLFIKEJ_01432 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFLFIKEJ_01433 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HFLFIKEJ_01434 4.5e-28 yjgN S Bacterial protein of unknown function (DUF898)
HFLFIKEJ_01435 8.3e-108 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HFLFIKEJ_01436 0.0 oatA I Acyltransferase
HFLFIKEJ_01437 3.5e-233 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFLFIKEJ_01438 7.7e-132 fruR K DeoR C terminal sensor domain
HFLFIKEJ_01439 9.4e-156 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HFLFIKEJ_01440 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HFLFIKEJ_01441 7.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
HFLFIKEJ_01442 2.9e-151 glcU U sugar transport
HFLFIKEJ_01443 3.7e-108 vanZ V VanZ like family
HFLFIKEJ_01444 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFLFIKEJ_01445 8e-129
HFLFIKEJ_01446 1.2e-103
HFLFIKEJ_01447 1.6e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFLFIKEJ_01448 4.6e-103 yjbF S SNARE associated Golgi protein
HFLFIKEJ_01449 1.1e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFLFIKEJ_01450 9e-195 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFLFIKEJ_01451 3.6e-207 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HFLFIKEJ_01452 3e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFLFIKEJ_01453 2.2e-38 yajC U Preprotein translocase
HFLFIKEJ_01454 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HFLFIKEJ_01455 3.9e-116 sirR K Helix-turn-helix diphteria tox regulatory element
HFLFIKEJ_01456 1.1e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFLFIKEJ_01457 1e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFLFIKEJ_01458 1.5e-239 ytoI K DRTGG domain
HFLFIKEJ_01459 1.1e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HFLFIKEJ_01460 8.1e-249 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFLFIKEJ_01461 1.2e-171
HFLFIKEJ_01462 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFLFIKEJ_01463 4e-43 yrzL S Belongs to the UPF0297 family
HFLFIKEJ_01464 8.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFLFIKEJ_01465 2.3e-53 yrzB S Belongs to the UPF0473 family
HFLFIKEJ_01466 2e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HFLFIKEJ_01467 8.6e-93 cvpA S Colicin V production protein
HFLFIKEJ_01468 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFLFIKEJ_01469 6.6e-53 trxA O Belongs to the thioredoxin family
HFLFIKEJ_01470 3.6e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFLFIKEJ_01471 1.8e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
HFLFIKEJ_01472 4e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFLFIKEJ_01473 1.2e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFLFIKEJ_01474 1.2e-82 yslB S Protein of unknown function (DUF2507)
HFLFIKEJ_01475 1.2e-277 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HFLFIKEJ_01476 1.8e-95 S Phosphoesterase
HFLFIKEJ_01477 8.9e-133 gla U Major intrinsic protein
HFLFIKEJ_01478 3e-84 ykuL S CBS domain
HFLFIKEJ_01479 4.6e-155 XK27_00890 S Domain of unknown function (DUF368)
HFLFIKEJ_01480 1.8e-156 ykuT M mechanosensitive ion channel
HFLFIKEJ_01482 1.2e-166 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFLFIKEJ_01483 5.6e-191 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFLFIKEJ_01484 1.8e-121 mhqD S Dienelactone hydrolase family
HFLFIKEJ_01485 4.1e-178 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
HFLFIKEJ_01486 2.9e-99 yvdD 3.2.2.10 S Belongs to the LOG family
HFLFIKEJ_01487 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFLFIKEJ_01488 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HFLFIKEJ_01489 8.9e-78 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFLFIKEJ_01490 9.9e-71 K Transcriptional regulator
HFLFIKEJ_01491 7.6e-107 EGP Major Facilitator Superfamily
HFLFIKEJ_01492 2.1e-31 cspC K Cold shock protein
HFLFIKEJ_01493 2.5e-13 chpR T PFAM SpoVT AbrB
HFLFIKEJ_01494 8.1e-82 yvbK 3.1.3.25 K GNAT family
HFLFIKEJ_01495 2.3e-108 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HFLFIKEJ_01496 1.2e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFLFIKEJ_01497 9.5e-242 pbuX F xanthine permease
HFLFIKEJ_01498 1.9e-203 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFLFIKEJ_01499 1.8e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFLFIKEJ_01500 8.6e-59
HFLFIKEJ_01501 3.5e-36
HFLFIKEJ_01502 4.2e-107 S alpha beta
HFLFIKEJ_01503 2.7e-80 MA20_25245 K FR47-like protein
HFLFIKEJ_01504 1.5e-57 hisB 2.7.7.71, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 5.3.1.28, 6.3.2.10 GT9 E HAD-hyrolase-like
HFLFIKEJ_01505 6.3e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
HFLFIKEJ_01506 5.4e-86 K Acetyltransferase (GNAT) domain
HFLFIKEJ_01507 3.5e-123
HFLFIKEJ_01508 3.6e-68 6.3.3.2 S ASCH
HFLFIKEJ_01509 6.1e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFLFIKEJ_01510 4.1e-198 ybiR P Citrate transporter
HFLFIKEJ_01511 2.1e-101
HFLFIKEJ_01512 9.5e-250 E Peptidase dimerisation domain
HFLFIKEJ_01513 2.1e-296 E ABC transporter, substratebinding protein
HFLFIKEJ_01514 3.1e-135
HFLFIKEJ_01515 0.0 cadA P P-type ATPase
HFLFIKEJ_01516 1e-75 hsp3 O Hsp20/alpha crystallin family
HFLFIKEJ_01517 5.9e-70 S Iron-sulphur cluster biosynthesis
HFLFIKEJ_01518 3.8e-206 htrA 3.4.21.107 O serine protease
HFLFIKEJ_01519 2.3e-10
HFLFIKEJ_01520 2.7e-154 vicX 3.1.26.11 S domain protein
HFLFIKEJ_01521 1.1e-141 yycI S YycH protein
HFLFIKEJ_01522 5.3e-259 yycH S YycH protein
HFLFIKEJ_01523 0.0 vicK 2.7.13.3 T Histidine kinase
HFLFIKEJ_01524 8.1e-131 K response regulator
HFLFIKEJ_01525 1.1e-121 S Alpha/beta hydrolase family
HFLFIKEJ_01526 9.3e-259 arpJ P ABC transporter permease
HFLFIKEJ_01527 5.1e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFLFIKEJ_01528 1.4e-267 argH 4.3.2.1 E argininosuccinate lyase
HFLFIKEJ_01529 2.6e-213 S Bacterial protein of unknown function (DUF871)
HFLFIKEJ_01530 3.5e-73 S Domain of unknown function (DUF3284)
HFLFIKEJ_01531 1.7e-238 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLFIKEJ_01532 6.9e-130 K UbiC transcription regulator-associated domain protein
HFLFIKEJ_01533 8.6e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_01534 4.9e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HFLFIKEJ_01535 1.7e-107 speG J Acetyltransferase (GNAT) domain
HFLFIKEJ_01536 2.2e-128 yrjD S LUD domain
HFLFIKEJ_01537 1e-289 lutB C 4Fe-4S dicluster domain
HFLFIKEJ_01538 3.1e-147 lutA C Cysteine-rich domain
HFLFIKEJ_01539 9.1e-101
HFLFIKEJ_01540 9.5e-53 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFLFIKEJ_01541 7.7e-213 S Bacterial protein of unknown function (DUF871)
HFLFIKEJ_01542 9.3e-71 S Domain of unknown function (DUF3284)
HFLFIKEJ_01543 4e-270 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLFIKEJ_01544 0.0 rafA 3.2.1.22 G alpha-galactosidase
HFLFIKEJ_01545 5.9e-132 S Belongs to the UPF0246 family
HFLFIKEJ_01546 2.6e-132 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
HFLFIKEJ_01547 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
HFLFIKEJ_01548 3.9e-110
HFLFIKEJ_01549 7.1e-99 S WxL domain surface cell wall-binding
HFLFIKEJ_01550 1.2e-146 frlD 2.7.1.218 G pfkB family carbohydrate kinase
HFLFIKEJ_01551 0.0 G Phosphodiester glycosidase
HFLFIKEJ_01552 6.7e-287 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
HFLFIKEJ_01553 6.9e-206 S Protein of unknown function (DUF917)
HFLFIKEJ_01554 5.1e-221 F Permease for cytosine/purines, uracil, thiamine, allantoin
HFLFIKEJ_01555 9.2e-123
HFLFIKEJ_01556 0.0 S Protein of unknown function (DUF1524)
HFLFIKEJ_01557 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
HFLFIKEJ_01558 0.0 S PglZ domain
HFLFIKEJ_01559 1.6e-75 cpsE M Bacterial sugar transferase
HFLFIKEJ_01560 2e-155 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFLFIKEJ_01561 7.6e-143 ywqE 3.1.3.48 GM PHP domain protein
HFLFIKEJ_01562 0.0 clpL O associated with various cellular activities
HFLFIKEJ_01563 6.7e-159 czcD P cation diffusion facilitator family transporter
HFLFIKEJ_01564 9e-164 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFLFIKEJ_01565 1.1e-37 veg S Biofilm formation stimulator VEG
HFLFIKEJ_01566 5.5e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFLFIKEJ_01567 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFLFIKEJ_01568 1.3e-145 tatD L hydrolase, TatD family
HFLFIKEJ_01569 5e-79 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HFLFIKEJ_01570 8e-63 nodB3 G Polysaccharide deacetylase
HFLFIKEJ_01571 2.6e-236 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFLFIKEJ_01572 3.7e-165 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HFLFIKEJ_01573 0.0 E amino acid
HFLFIKEJ_01574 1.4e-136 cysA V ABC transporter, ATP-binding protein
HFLFIKEJ_01575 0.0 V FtsX-like permease family
HFLFIKEJ_01576 2.5e-169 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HFLFIKEJ_01577 1.2e-128 pgm3 G Phosphoglycerate mutase family
HFLFIKEJ_01578 2.5e-183 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HFLFIKEJ_01579 3.7e-217 mntH P H( )-stimulated, divalent metal cation uptake system
HFLFIKEJ_01580 2.9e-81 yjhE S Phage tail protein
HFLFIKEJ_01581 1.2e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HFLFIKEJ_01582 0.0 yjbQ P TrkA C-terminal domain protein
HFLFIKEJ_01583 2.3e-27
HFLFIKEJ_01584 1.2e-09
HFLFIKEJ_01585 0.0 helD 3.6.4.12 L DNA helicase
HFLFIKEJ_01586 2.1e-82 ykhA 3.1.2.20 I Thioesterase superfamily
HFLFIKEJ_01587 4.8e-276 pipD E Dipeptidase
HFLFIKEJ_01588 3.5e-40
HFLFIKEJ_01589 9.8e-53
HFLFIKEJ_01590 7.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HFLFIKEJ_01591 2.1e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HFLFIKEJ_01592 8.8e-39
HFLFIKEJ_01593 4.6e-101 D nuclear chromosome segregation
HFLFIKEJ_01595 4.6e-26 S Bacteriophage abortive infection AbiH
HFLFIKEJ_01596 1.1e-139 L Transposase IS66 family
HFLFIKEJ_01597 6.4e-70 L Transposase IS66 family
HFLFIKEJ_01598 1.5e-08 L IS66 Orf2 like protein
HFLFIKEJ_01600 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFLFIKEJ_01601 1.2e-61 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HFLFIKEJ_01602 3.9e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HFLFIKEJ_01603 3.5e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFLFIKEJ_01604 1.3e-111 cutC P Participates in the control of copper homeostasis
HFLFIKEJ_01605 7.7e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFLFIKEJ_01606 7.8e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HFLFIKEJ_01607 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFLFIKEJ_01608 2.7e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
HFLFIKEJ_01609 1.2e-103 yjbK S CYTH
HFLFIKEJ_01610 1.5e-115 yjbH Q Thioredoxin
HFLFIKEJ_01611 4.1e-211 coiA 3.6.4.12 S Competence protein
HFLFIKEJ_01612 1.3e-243 XK27_08635 S UPF0210 protein
HFLFIKEJ_01613 1.5e-37 gcvR T Belongs to the UPF0237 family
HFLFIKEJ_01614 3.8e-222 cpdA S Calcineurin-like phosphoesterase
HFLFIKEJ_01615 7.4e-225 malY 4.4.1.8 E Aminotransferase, class I
HFLFIKEJ_01616 4.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HFLFIKEJ_01618 5.1e-95 FNV0100 F NUDIX domain
HFLFIKEJ_01619 2.5e-139 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFLFIKEJ_01620 3.3e-35 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HFLFIKEJ_01621 1.7e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFLFIKEJ_01622 2.4e-279 ytgP S Polysaccharide biosynthesis protein
HFLFIKEJ_01623 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFLFIKEJ_01624 9.7e-118 3.6.1.27 I Acid phosphatase homologues
HFLFIKEJ_01625 1e-112 S Domain of unknown function (DUF4811)
HFLFIKEJ_01626 4e-265 lmrB EGP Major facilitator Superfamily
HFLFIKEJ_01627 1.1e-80 merR K MerR HTH family regulatory protein
HFLFIKEJ_01628 7.3e-275 emrY EGP Major facilitator Superfamily
HFLFIKEJ_01629 8.6e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFLFIKEJ_01630 1.5e-99
HFLFIKEJ_01634 2.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFLFIKEJ_01635 5.4e-71 WQ51_03320 S Protein of unknown function (DUF1149)
HFLFIKEJ_01636 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HFLFIKEJ_01637 3e-229 ymfF S Peptidase M16 inactive domain protein
HFLFIKEJ_01638 2.2e-243 ymfH S Peptidase M16
HFLFIKEJ_01639 1.3e-128 IQ Enoyl-(Acyl carrier protein) reductase
HFLFIKEJ_01640 2e-116 ymfM S Helix-turn-helix domain
HFLFIKEJ_01641 1.6e-103 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFLFIKEJ_01642 4e-226 cinA 3.5.1.42 S Belongs to the CinA family
HFLFIKEJ_01643 3.3e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFLFIKEJ_01644 1.3e-12
HFLFIKEJ_01645 1.7e-242 rny S Endoribonuclease that initiates mRNA decay
HFLFIKEJ_01646 2.1e-117 yvyE 3.4.13.9 S YigZ family
HFLFIKEJ_01647 1.4e-234 comFA L Helicase C-terminal domain protein
HFLFIKEJ_01648 1.3e-90 comFC S Competence protein
HFLFIKEJ_01649 5.4e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFLFIKEJ_01650 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFLFIKEJ_01651 8.9e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFLFIKEJ_01652 1.9e-124 ftsE D ABC transporter
HFLFIKEJ_01653 1.8e-159 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HFLFIKEJ_01654 6.5e-196 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HFLFIKEJ_01655 5.2e-130 K response regulator
HFLFIKEJ_01656 6.4e-304 phoR 2.7.13.3 T Histidine kinase
HFLFIKEJ_01657 1.2e-155 pstS P Phosphate
HFLFIKEJ_01658 3.4e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HFLFIKEJ_01659 1.1e-156 pstA P Phosphate transport system permease protein PstA
HFLFIKEJ_01660 6.9e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFLFIKEJ_01661 7.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFLFIKEJ_01662 1e-119 phoU P Plays a role in the regulation of phosphate uptake
HFLFIKEJ_01663 2.5e-253 yjjP S Putative threonine/serine exporter
HFLFIKEJ_01664 7e-59
HFLFIKEJ_01665 1.3e-225 mesE M Transport protein ComB
HFLFIKEJ_01666 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HFLFIKEJ_01667 3e-223 mtnE 2.6.1.83 E Aminotransferase
HFLFIKEJ_01668 1.1e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HFLFIKEJ_01669 1.1e-149 M NLPA lipoprotein
HFLFIKEJ_01672 8.1e-199 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
HFLFIKEJ_01673 3.3e-225 amd 3.5.1.47 E Peptidase family M20/M25/M40
HFLFIKEJ_01674 2.6e-80 S Threonine/Serine exporter, ThrE
HFLFIKEJ_01675 3.2e-133 thrE S Putative threonine/serine exporter
HFLFIKEJ_01677 3.8e-31
HFLFIKEJ_01678 1.4e-271 V ABC transporter transmembrane region
HFLFIKEJ_01680 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFLFIKEJ_01681 6.9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFLFIKEJ_01682 1.9e-138 jag S R3H domain protein
HFLFIKEJ_01683 6.4e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFLFIKEJ_01684 1.9e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFLFIKEJ_01685 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HFLFIKEJ_01686 3.5e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFLFIKEJ_01687 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFLFIKEJ_01688 2.9e-31 yaaA S S4 domain protein YaaA
HFLFIKEJ_01689 1.6e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFLFIKEJ_01690 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFLFIKEJ_01691 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFLFIKEJ_01692 1.7e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFLFIKEJ_01693 1.9e-59 ssb_2 L Single-strand binding protein family
HFLFIKEJ_01694 2.7e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HFLFIKEJ_01695 1.1e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFLFIKEJ_01696 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFLFIKEJ_01698 1.5e-91 yhbO 3.5.1.124 S DJ-1/PfpI family
HFLFIKEJ_01699 4e-281 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
HFLFIKEJ_01700 3.8e-182 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
HFLFIKEJ_01701 2.1e-28
HFLFIKEJ_01702 1.5e-82 V Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
HFLFIKEJ_01703 6.7e-162 V ABC transporter
HFLFIKEJ_01704 1.1e-187 amtB P Ammonium Transporter Family
HFLFIKEJ_01705 7.8e-213 P Pyridine nucleotide-disulphide oxidoreductase
HFLFIKEJ_01706 6.9e-125 usp 3.5.1.28 CBM50 D CHAP domain
HFLFIKEJ_01707 0.0 ylbB V ABC transporter permease
HFLFIKEJ_01708 1.1e-127 macB V ABC transporter, ATP-binding protein
HFLFIKEJ_01709 2.5e-95 K transcriptional regulator
HFLFIKEJ_01710 1.5e-152 supH G Sucrose-6F-phosphate phosphohydrolase
HFLFIKEJ_01711 1.4e-45
HFLFIKEJ_01712 4.1e-128 S membrane transporter protein
HFLFIKEJ_01713 2.1e-103 S Protein of unknown function (DUF1211)
HFLFIKEJ_01714 1.7e-113 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HFLFIKEJ_01715 1.3e-54
HFLFIKEJ_01716 8.1e-287 pipD E Dipeptidase
HFLFIKEJ_01717 2.3e-105 S Membrane
HFLFIKEJ_01718 1.9e-84
HFLFIKEJ_01719 2.2e-52
HFLFIKEJ_01720 4.9e-52
HFLFIKEJ_01721 1.1e-179 ybfG M peptidoglycan-binding domain-containing protein
HFLFIKEJ_01722 2.4e-122 azlC E branched-chain amino acid
HFLFIKEJ_01723 1.5e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HFLFIKEJ_01724 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HFLFIKEJ_01725 0.0 M Glycosyl hydrolase family 59
HFLFIKEJ_01726 1.4e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HFLFIKEJ_01727 4.6e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HFLFIKEJ_01728 1.2e-279 uxaC 5.3.1.12 G glucuronate isomerase
HFLFIKEJ_01729 1.7e-217 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HFLFIKEJ_01730 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
HFLFIKEJ_01731 1e-266 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HFLFIKEJ_01732 5.6e-245 G Major Facilitator
HFLFIKEJ_01733 1.2e-126 kdgR K FCD domain
HFLFIKEJ_01734 1.5e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HFLFIKEJ_01735 0.0 M Glycosyl hydrolase family 59
HFLFIKEJ_01736 5.6e-58
HFLFIKEJ_01737 1e-64 S pyridoxamine 5-phosphate
HFLFIKEJ_01738 2.6e-242 EGP Major facilitator Superfamily
HFLFIKEJ_01740 0.0 ydgH S MMPL family
HFLFIKEJ_01741 5e-105 K Tetracycline repressor, C-terminal all-alpha domain
HFLFIKEJ_01742 4.8e-121 S Sulfite exporter TauE/SafE
HFLFIKEJ_01743 1.3e-246 3.5.4.28, 3.5.4.31 F Amidohydrolase family
HFLFIKEJ_01744 3.3e-69 S An automated process has identified a potential problem with this gene model
HFLFIKEJ_01745 1e-148 S Protein of unknown function (DUF3100)
HFLFIKEJ_01747 1.9e-110 opuCD P Binding-protein-dependent transport system inner membrane component
HFLFIKEJ_01748 7.8e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFLFIKEJ_01749 4.7e-106 opuCB E ABC transporter permease
HFLFIKEJ_01750 1.6e-214 opuCA E ABC transporter, ATP-binding protein
HFLFIKEJ_01751 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
HFLFIKEJ_01752 6.2e-32 copZ P Heavy-metal-associated domain
HFLFIKEJ_01753 1.2e-100 dps P Belongs to the Dps family
HFLFIKEJ_01754 6.8e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HFLFIKEJ_01755 1.3e-96 K Bacterial regulatory proteins, tetR family
HFLFIKEJ_01756 1.6e-83 S Protein of unknown function with HXXEE motif
HFLFIKEJ_01758 1e-159 S CAAX protease self-immunity
HFLFIKEJ_01760 2.5e-136 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HFLFIKEJ_01761 1.4e-228 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HFLFIKEJ_01762 1.1e-104 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HFLFIKEJ_01763 7.3e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HFLFIKEJ_01764 1.5e-181 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFLFIKEJ_01765 2.4e-304 norB EGP Major Facilitator
HFLFIKEJ_01766 5.2e-110 K Bacterial regulatory proteins, tetR family
HFLFIKEJ_01767 3.8e-41
HFLFIKEJ_01768 5.1e-64
HFLFIKEJ_01770 6.8e-107 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
HFLFIKEJ_01771 2.8e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFLFIKEJ_01772 3.5e-163 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFLFIKEJ_01773 1.9e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFLFIKEJ_01774 1.1e-71 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFLFIKEJ_01775 6.2e-257 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFLFIKEJ_01776 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFLFIKEJ_01777 2e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
HFLFIKEJ_01778 1.4e-118 GM NmrA-like family
HFLFIKEJ_01779 1.8e-84
HFLFIKEJ_01780 3.9e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
HFLFIKEJ_01781 4.7e-20
HFLFIKEJ_01783 5.9e-53 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFLFIKEJ_01784 8.2e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFLFIKEJ_01785 1.2e-285 G MFS/sugar transport protein
HFLFIKEJ_01786 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase concanavalin-like domain
HFLFIKEJ_01787 4.6e-169 ssuA P NMT1-like family
HFLFIKEJ_01788 1.9e-294 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
HFLFIKEJ_01789 5.6e-236 yfiQ I Acyltransferase family
HFLFIKEJ_01790 1.7e-120 ssuB P ATPases associated with a variety of cellular activities
HFLFIKEJ_01791 1.6e-146 ssuC U Binding-protein-dependent transport system inner membrane component
HFLFIKEJ_01792 1.4e-121 S B3/4 domain
HFLFIKEJ_01793 3.5e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFLFIKEJ_01794 7.3e-14
HFLFIKEJ_01795 0.0 V ABC transporter
HFLFIKEJ_01796 0.0 V ATPases associated with a variety of cellular activities
HFLFIKEJ_01797 2.1e-208 EGP Transmembrane secretion effector
HFLFIKEJ_01798 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HFLFIKEJ_01799 7e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFLFIKEJ_01800 1.1e-102 K Bacterial regulatory proteins, tetR family
HFLFIKEJ_01801 2.9e-185 yxeA V FtsX-like permease family
HFLFIKEJ_01802 1.4e-127 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
HFLFIKEJ_01803 6.4e-34
HFLFIKEJ_01804 1.1e-175 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HFLFIKEJ_01805 2e-126 S Domain of unknown function (DUF4867)
HFLFIKEJ_01806 9.4e-189 V Beta-lactamase
HFLFIKEJ_01807 1.7e-28
HFLFIKEJ_01809 1e-199 gatC G PTS system sugar-specific permease component
HFLFIKEJ_01810 3.8e-24 yvgN C Aldo keto reductase
HFLFIKEJ_01811 2.7e-140 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HFLFIKEJ_01812 2.7e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFLFIKEJ_01813 3.6e-85 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFLFIKEJ_01815 1.4e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HFLFIKEJ_01816 1.2e-219 hpk31 2.7.13.3 T Histidine kinase
HFLFIKEJ_01817 2.5e-121 K response regulator
HFLFIKEJ_01818 1.5e-118
HFLFIKEJ_01819 5.1e-268 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFLFIKEJ_01820 1.6e-140 XK27_01040 S Protein of unknown function (DUF1129)
HFLFIKEJ_01821 1.5e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFLFIKEJ_01822 1.3e-30 yyzM S Bacterial protein of unknown function (DUF951)
HFLFIKEJ_01823 2e-155 spo0J K Belongs to the ParB family
HFLFIKEJ_01824 2.5e-138 soj D Sporulation initiation inhibitor
HFLFIKEJ_01825 2.4e-142 noc K Belongs to the ParB family
HFLFIKEJ_01826 2.3e-133 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HFLFIKEJ_01827 2.2e-66
HFLFIKEJ_01828 1e-127 cobQ S glutamine amidotransferase
HFLFIKEJ_01830 3e-105 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HFLFIKEJ_01831 6.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HFLFIKEJ_01832 6.7e-146 S Protein of unknown function (DUF979)
HFLFIKEJ_01833 1.7e-114 S Protein of unknown function (DUF969)
HFLFIKEJ_01834 1.8e-129 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HFLFIKEJ_01835 7.9e-65 asp2 S Asp23 family, cell envelope-related function
HFLFIKEJ_01836 5.1e-61 asp23 S Asp23 family, cell envelope-related function
HFLFIKEJ_01837 2.5e-29
HFLFIKEJ_01838 1.5e-89 S Protein conserved in bacteria
HFLFIKEJ_01839 6.4e-38 S Transglycosylase associated protein
HFLFIKEJ_01840 9.1e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
HFLFIKEJ_01841 4.4e-172 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLFIKEJ_01842 6.7e-27
HFLFIKEJ_01843 3.4e-36
HFLFIKEJ_01844 9.2e-83 fld C Flavodoxin
HFLFIKEJ_01845 1.6e-51
HFLFIKEJ_01846 6.5e-65
HFLFIKEJ_01848 1e-55 ywjH S Protein of unknown function (DUF1634)
HFLFIKEJ_01849 4e-129 yxaA S Sulfite exporter TauE/SafE
HFLFIKEJ_01850 1.6e-233 S TPM domain
HFLFIKEJ_01851 1.7e-116
HFLFIKEJ_01852 4.7e-260 nox 1.6.3.4 C NADH oxidase
HFLFIKEJ_01853 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
HFLFIKEJ_01854 2.3e-212 S nuclear-transcribed mRNA catabolic process, no-go decay
HFLFIKEJ_01855 3e-81 S NUDIX domain
HFLFIKEJ_01856 1.6e-74
HFLFIKEJ_01857 2.5e-118 V ATPases associated with a variety of cellular activities
HFLFIKEJ_01858 9.3e-122
HFLFIKEJ_01859 8.6e-117
HFLFIKEJ_01860 2.2e-76
HFLFIKEJ_01861 1.8e-303 oppA E ABC transporter, substratebinding protein
HFLFIKEJ_01862 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HFLFIKEJ_01864 6.3e-15
HFLFIKEJ_01865 8.6e-47 V ATPase activity
HFLFIKEJ_01867 1.7e-89
HFLFIKEJ_01870 5.7e-248 bmr3 EGP Major facilitator Superfamily
HFLFIKEJ_01871 7.7e-137 magIII L Base excision DNA repair protein, HhH-GPD family
HFLFIKEJ_01872 2.2e-159 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
HFLFIKEJ_01873 7.3e-242 sgaT 2.7.1.194 S PTS system sugar-specific permease component
HFLFIKEJ_01874 6.4e-162 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HFLFIKEJ_01875 6e-285 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HFLFIKEJ_01876 3.2e-133 K DeoR C terminal sensor domain
HFLFIKEJ_01877 6.4e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFLFIKEJ_01878 1.6e-252 rarA L recombination factor protein RarA
HFLFIKEJ_01879 9.4e-58
HFLFIKEJ_01880 2.7e-148 yhaI S Protein of unknown function (DUF805)
HFLFIKEJ_01881 9.2e-270 L Mga helix-turn-helix domain
HFLFIKEJ_01882 6.2e-183 ynjC S Cell surface protein
HFLFIKEJ_01883 4.1e-123 yqcC S WxL domain surface cell wall-binding
HFLFIKEJ_01885 0.0
HFLFIKEJ_01886 5.6e-106 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HFLFIKEJ_01887 4.5e-43
HFLFIKEJ_01888 4.9e-187 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFLFIKEJ_01889 3.4e-52 S DsrE/DsrF-like family
HFLFIKEJ_01890 1.4e-254 pbuO S permease
HFLFIKEJ_01891 1.2e-53 S Protein of unknown function (DUF1516)
HFLFIKEJ_01892 4e-57 ypaA S Protein of unknown function (DUF1304)
HFLFIKEJ_01893 6.1e-40
HFLFIKEJ_01894 5.8e-132 K UTRA
HFLFIKEJ_01895 3.5e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFLFIKEJ_01896 7.2e-253 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLFIKEJ_01897 8e-85
HFLFIKEJ_01898 1.3e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFLFIKEJ_01899 4.5e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_01900 1.2e-191 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFLFIKEJ_01901 8.2e-90 ogt 2.1.1.63 L Methyltransferase
HFLFIKEJ_01902 1.6e-120 K Transcriptional regulatory protein, C terminal
HFLFIKEJ_01903 2.9e-201 T PhoQ Sensor
HFLFIKEJ_01904 5.7e-86
HFLFIKEJ_01905 1.5e-224 EGP Major facilitator Superfamily
HFLFIKEJ_01906 1.7e-29
HFLFIKEJ_01907 2.5e-116
HFLFIKEJ_01908 1.8e-119
HFLFIKEJ_01909 1.5e-158 V ABC transporter
HFLFIKEJ_01910 7.7e-79 FG adenosine 5'-monophosphoramidase activity
HFLFIKEJ_01911 5.2e-248 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
HFLFIKEJ_01912 3.5e-100 3.1.3.18 J HAD-hyrolase-like
HFLFIKEJ_01913 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFLFIKEJ_01914 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HFLFIKEJ_01915 1.1e-218 rpsA 1.17.7.4 J Ribosomal protein S1
HFLFIKEJ_01916 2.6e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HFLFIKEJ_01917 3.8e-55 M Lysin motif
HFLFIKEJ_01918 1.3e-265 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HFLFIKEJ_01919 1e-179 ypbB 5.1.3.1 S Helix-turn-helix domain
HFLFIKEJ_01920 1.4e-45 fer C 4Fe-4S single cluster domain of Ferredoxin I
HFLFIKEJ_01921 2.4e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFLFIKEJ_01922 9.4e-138 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFLFIKEJ_01923 3.3e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFLFIKEJ_01924 7.3e-127 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFLFIKEJ_01925 3.4e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFLFIKEJ_01926 3.3e-166 xerD D recombinase XerD
HFLFIKEJ_01927 3.4e-163 cvfB S S1 domain
HFLFIKEJ_01928 7.2e-72 yeaL S Protein of unknown function (DUF441)
HFLFIKEJ_01929 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HFLFIKEJ_01930 3.5e-177 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFLFIKEJ_01931 0.0 dnaE 2.7.7.7 L DNA polymerase
HFLFIKEJ_01932 1.3e-19 S Protein of unknown function (DUF2929)
HFLFIKEJ_01933 9.2e-145
HFLFIKEJ_01934 4.7e-301 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
HFLFIKEJ_01935 9.6e-95 M1-874 K Domain of unknown function (DUF1836)
HFLFIKEJ_01936 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HFLFIKEJ_01937 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFLFIKEJ_01938 1.3e-46 yrvD S Lipopolysaccharide assembly protein A domain
HFLFIKEJ_01939 9.6e-141 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HFLFIKEJ_01940 7.7e-120 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFLFIKEJ_01941 5.9e-64
HFLFIKEJ_01942 3.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFLFIKEJ_01943 1.7e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFLFIKEJ_01944 1.5e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HFLFIKEJ_01945 2.2e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFLFIKEJ_01946 3.6e-188 cggR K Putative sugar-binding domain
HFLFIKEJ_01948 2.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFLFIKEJ_01949 5.5e-80 ohrR K helix_turn_helix multiple antibiotic resistance protein
HFLFIKEJ_01950 3.7e-171 whiA K May be required for sporulation
HFLFIKEJ_01951 1.7e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HFLFIKEJ_01952 1.3e-165 rapZ S Displays ATPase and GTPase activities
HFLFIKEJ_01953 6.7e-85 S Short repeat of unknown function (DUF308)
HFLFIKEJ_01954 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFLFIKEJ_01955 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFLFIKEJ_01956 7.9e-117 yfbR S HD containing hydrolase-like enzyme
HFLFIKEJ_01957 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFLFIKEJ_01958 1.5e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFLFIKEJ_01959 2e-194 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HFLFIKEJ_01960 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFLFIKEJ_01961 2.8e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFLFIKEJ_01962 1.3e-46 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HFLFIKEJ_01963 2.1e-31
HFLFIKEJ_01964 5.5e-214 yvlB S Putative adhesin
HFLFIKEJ_01965 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HFLFIKEJ_01966 1.2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HFLFIKEJ_01967 5e-263 K Mga helix-turn-helix domain
HFLFIKEJ_01968 0.0 N domain, Protein
HFLFIKEJ_01969 3.5e-135 S WxL domain surface cell wall-binding
HFLFIKEJ_01971 3.7e-188 S Cell surface protein
HFLFIKEJ_01973 4.6e-118 ybhL S Inhibitor of apoptosis-promoting Bax1
HFLFIKEJ_01974 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFLFIKEJ_01975 6e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFLFIKEJ_01976 2.3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFLFIKEJ_01977 3.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFLFIKEJ_01978 5.3e-248 dnaB L replication initiation and membrane attachment
HFLFIKEJ_01979 2e-169 dnaI L Primosomal protein DnaI
HFLFIKEJ_01980 1.6e-224 V regulation of methylation-dependent chromatin silencing
HFLFIKEJ_01981 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFLFIKEJ_01982 3.6e-64
HFLFIKEJ_01983 5e-120 S WxL domain surface cell wall-binding
HFLFIKEJ_01984 4.7e-61
HFLFIKEJ_01985 7.4e-113 N WxL domain surface cell wall-binding
HFLFIKEJ_01986 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HFLFIKEJ_01987 1.1e-167 yicL EG EamA-like transporter family
HFLFIKEJ_01988 2e-300
HFLFIKEJ_01989 1.1e-144 CcmA5 V ABC transporter
HFLFIKEJ_01990 6.2e-78 S ECF-type riboflavin transporter, S component
HFLFIKEJ_01991 6.1e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HFLFIKEJ_01992 1.5e-163 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
HFLFIKEJ_01993 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFLFIKEJ_01994 0.0 XK27_09600 V ABC transporter, ATP-binding protein
HFLFIKEJ_01995 0.0 V ABC transporter
HFLFIKEJ_01996 7.2e-220 oxlT P Major Facilitator Superfamily
HFLFIKEJ_01997 8.5e-128 treR K UTRA
HFLFIKEJ_01998 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HFLFIKEJ_01999 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HFLFIKEJ_02000 2e-212 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HFLFIKEJ_02001 2.5e-267 yfnA E Amino Acid
HFLFIKEJ_02002 2.5e-172 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HFLFIKEJ_02003 1.9e-250 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HFLFIKEJ_02004 4.6e-31 K 'Cold-shock' DNA-binding domain
HFLFIKEJ_02005 4.1e-69
HFLFIKEJ_02006 3.5e-76 O OsmC-like protein
HFLFIKEJ_02007 2.3e-281 lsa S ABC transporter
HFLFIKEJ_02008 1e-113 ylbE GM NAD(P)H-binding
HFLFIKEJ_02009 2.9e-159 yeaE S Aldo/keto reductase family
HFLFIKEJ_02010 1.9e-256 yifK E Amino acid permease
HFLFIKEJ_02011 1.4e-282 S Protein of unknown function (DUF3800)
HFLFIKEJ_02012 0.0 yjcE P Sodium proton antiporter
HFLFIKEJ_02013 2.2e-56 S Protein of unknown function (DUF3021)
HFLFIKEJ_02014 4.8e-68 K LytTr DNA-binding domain
HFLFIKEJ_02015 3.1e-148 cylB V ABC-2 type transporter
HFLFIKEJ_02016 1.4e-156 cylA V ABC transporter
HFLFIKEJ_02017 8.3e-145 S Alpha/beta hydrolase of unknown function (DUF915)
HFLFIKEJ_02018 8.7e-116 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HFLFIKEJ_02019 4.5e-52 ybjQ S Belongs to the UPF0145 family
HFLFIKEJ_02020 5.1e-95 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
HFLFIKEJ_02021 2e-158 3.5.1.10 C nadph quinone reductase
HFLFIKEJ_02022 1.3e-243 amt P ammonium transporter
HFLFIKEJ_02023 1.4e-178 yfeX P Peroxidase
HFLFIKEJ_02024 1.1e-118 yhiD S MgtC family
HFLFIKEJ_02025 2.7e-146 F DNA RNA non-specific endonuclease
HFLFIKEJ_02027 1.2e-10
HFLFIKEJ_02028 2.3e-311 ybiT S ABC transporter, ATP-binding protein
HFLFIKEJ_02029 3.3e-276 mutS L ATPase domain of DNA mismatch repair MUTS family
HFLFIKEJ_02030 2e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
HFLFIKEJ_02031 5.6e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HFLFIKEJ_02032 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HFLFIKEJ_02033 5.9e-296 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFLFIKEJ_02034 5.2e-133 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
HFLFIKEJ_02037 6.5e-138 lacT K PRD domain
HFLFIKEJ_02038 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HFLFIKEJ_02039 4.7e-247 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HFLFIKEJ_02040 1.9e-50 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HFLFIKEJ_02041 6.9e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFLFIKEJ_02042 1.5e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HFLFIKEJ_02043 1e-281 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HFLFIKEJ_02044 5.6e-162 K Transcriptional regulator
HFLFIKEJ_02045 1.4e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HFLFIKEJ_02047 3.3e-70 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLFIKEJ_02048 1.7e-48 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_02049 4.3e-21 gatC G PTS system sugar-specific permease component
HFLFIKEJ_02050 5.4e-37 L PFAM transposase, IS4 family protein
HFLFIKEJ_02051 5.5e-111 L PFAM transposase, IS4 family protein
HFLFIKEJ_02052 1.8e-287 L Reverse transcriptase (RNA-dependent DNA polymerase)
HFLFIKEJ_02054 3.2e-50 lciIC K Helix-turn-helix XRE-family like proteins
HFLFIKEJ_02056 0.0 lytN 3.5.1.104 M LysM domain
HFLFIKEJ_02058 2.7e-23 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HFLFIKEJ_02059 7.4e-114 zmp3 O Zinc-dependent metalloprotease
HFLFIKEJ_02060 1.2e-136 2.7.1.39 S Phosphotransferase enzyme family
HFLFIKEJ_02061 5.5e-68 S Iron-sulphur cluster biosynthesis
HFLFIKEJ_02062 7.1e-284 V ABC transporter transmembrane region
HFLFIKEJ_02063 9.6e-284 V ABC transporter transmembrane region
HFLFIKEJ_02064 6.7e-38
HFLFIKEJ_02065 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
HFLFIKEJ_02066 1.3e-168 oppB P Binding-protein-dependent transport system inner membrane component
HFLFIKEJ_02067 4e-173 amiD P N-terminal TM domain of oligopeptide transport permease C
HFLFIKEJ_02068 1.7e-48
HFLFIKEJ_02069 6.8e-198 oppD P Oligopeptide/dipeptide transporter, C-terminal region
HFLFIKEJ_02070 3.8e-162 oppF P Oligopeptide/dipeptide transporter, C-terminal region
HFLFIKEJ_02071 2.1e-17
HFLFIKEJ_02072 1.4e-127 skfE V ATPases associated with a variety of cellular activities
HFLFIKEJ_02073 3.6e-61 yvoA_1 K Transcriptional regulator, GntR family
HFLFIKEJ_02074 1e-159 S Alpha beta hydrolase
HFLFIKEJ_02075 1.8e-123 ybbM S Uncharacterised protein family (UPF0014)
HFLFIKEJ_02076 6.5e-119 ybbL S ABC transporter, ATP-binding protein
HFLFIKEJ_02077 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HFLFIKEJ_02078 3.5e-219 ysaA V RDD family
HFLFIKEJ_02079 3.7e-196 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFLFIKEJ_02080 2.1e-163 menA 2.5.1.74 M UbiA prenyltransferase family
HFLFIKEJ_02081 2e-172 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HFLFIKEJ_02082 8.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HFLFIKEJ_02083 1.5e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFLFIKEJ_02084 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
HFLFIKEJ_02085 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
HFLFIKEJ_02086 1.7e-78 F nucleoside 2-deoxyribosyltransferase
HFLFIKEJ_02087 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HFLFIKEJ_02088 3.1e-63 S Domain of unknown function (DUF4430)
HFLFIKEJ_02089 7.9e-86 S ECF transporter, substrate-specific component
HFLFIKEJ_02090 2.4e-90 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
HFLFIKEJ_02091 4.8e-263 nylA 3.5.1.4 J Belongs to the amidase family
HFLFIKEJ_02092 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HFLFIKEJ_02093 4.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFLFIKEJ_02094 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFLFIKEJ_02095 7.2e-95 yqaB S Acetyltransferase (GNAT) domain
HFLFIKEJ_02096 4.2e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HFLFIKEJ_02097 2.5e-302 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HFLFIKEJ_02098 3.6e-290 2.4.1.52 GT4 M Glycosyl transferases group 1
HFLFIKEJ_02099 4.5e-171 yqhA G Aldose 1-epimerase
HFLFIKEJ_02100 1.3e-125 T LytTr DNA-binding domain
HFLFIKEJ_02101 1.1e-167 2.7.13.3 T GHKL domain
HFLFIKEJ_02102 9.2e-304 V ABC transporter
HFLFIKEJ_02103 0.0 V ABC transporter
HFLFIKEJ_02104 1.3e-28 K Transcriptional
HFLFIKEJ_02105 5.7e-66
HFLFIKEJ_02106 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFLFIKEJ_02107 4.1e-173 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HFLFIKEJ_02108 4.8e-11 gluP 3.4.21.105 S proteolysis
HFLFIKEJ_02109 8.6e-153 yunF F Protein of unknown function DUF72
HFLFIKEJ_02110 3.8e-92 3.6.1.55 F NUDIX domain
HFLFIKEJ_02111 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HFLFIKEJ_02112 5.3e-107 yiiE S Protein of unknown function (DUF1211)
HFLFIKEJ_02113 5.7e-129 cobB K Sir2 family
HFLFIKEJ_02114 2.8e-17
HFLFIKEJ_02115 1.5e-169
HFLFIKEJ_02116 2.5e-97 yxkA S Phosphatidylethanolamine-binding protein
HFLFIKEJ_02118 1.6e-161 ypuA S Protein of unknown function (DUF1002)
HFLFIKEJ_02119 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HFLFIKEJ_02120 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFLFIKEJ_02121 9.5e-286 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HFLFIKEJ_02122 3.9e-173 S Aldo keto reductase
HFLFIKEJ_02123 9.3e-155 bioC 2.1.1.187, 2.1.1.197 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HFLFIKEJ_02124 1.7e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HFLFIKEJ_02125 1e-238 dinF V MatE
HFLFIKEJ_02127 3.3e-110 S TPM domain
HFLFIKEJ_02128 3.1e-102 lemA S LemA family
HFLFIKEJ_02129 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFLFIKEJ_02130 5.4e-74 EGP Major Facilitator Superfamily
HFLFIKEJ_02131 1e-251 gshR 1.8.1.7 C Glutathione reductase
HFLFIKEJ_02132 6.6e-176 proV E ABC transporter, ATP-binding protein
HFLFIKEJ_02133 4.9e-274 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFLFIKEJ_02135 0.0 helD 3.6.4.12 L DNA helicase
HFLFIKEJ_02136 2.7e-146 rlrG K Transcriptional regulator
HFLFIKEJ_02137 4.8e-174 shetA P Voltage-dependent anion channel
HFLFIKEJ_02138 2.5e-133 nodJ V ABC-2 type transporter
HFLFIKEJ_02139 4.9e-134 nodI V ABC transporter
HFLFIKEJ_02140 1.4e-130 ydfF K Transcriptional
HFLFIKEJ_02141 3.6e-109 S CAAX protease self-immunity
HFLFIKEJ_02143 1.5e-276 V ABC transporter transmembrane region
HFLFIKEJ_02144 7.9e-109 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFLFIKEJ_02145 7.2e-71 K MarR family
HFLFIKEJ_02146 0.0 uvrA3 L excinuclease ABC
HFLFIKEJ_02147 8.3e-190 yghZ C Aldo keto reductase family protein
HFLFIKEJ_02148 1.8e-142 S hydrolase
HFLFIKEJ_02149 1.2e-58
HFLFIKEJ_02150 4.8e-12
HFLFIKEJ_02151 1.3e-42
HFLFIKEJ_02152 5.1e-28
HFLFIKEJ_02154 3e-62 V ABC transporter
HFLFIKEJ_02156 2.6e-118 yoaK S Protein of unknown function (DUF1275)
HFLFIKEJ_02157 3.1e-127 yjhF G Phosphoglycerate mutase family
HFLFIKEJ_02158 5.8e-149 yitU 3.1.3.104 S hydrolase
HFLFIKEJ_02159 2.3e-89 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFLFIKEJ_02160 1.7e-165 K LysR substrate binding domain
HFLFIKEJ_02161 3.9e-226 EK Aminotransferase, class I
HFLFIKEJ_02163 2.9e-45
HFLFIKEJ_02164 9.4e-58
HFLFIKEJ_02165 5.6e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFLFIKEJ_02166 7.3e-116 ydfK S Protein of unknown function (DUF554)
HFLFIKEJ_02167 5.1e-89
HFLFIKEJ_02169 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLFIKEJ_02170 3.7e-168 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HFLFIKEJ_02171 1.1e-130 rpl K Helix-turn-helix domain, rpiR family
HFLFIKEJ_02172 1.8e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFLFIKEJ_02173 2.3e-136 K UTRA domain
HFLFIKEJ_02174 1.4e-253 fucA 3.2.1.51 GH29 G Alpha-L-fucosidase
HFLFIKEJ_02175 4.8e-160 2.7.1.191 G PTS system sorbose subfamily IIB component
HFLFIKEJ_02176 8.6e-129 G PTS system sorbose-specific iic component
HFLFIKEJ_02177 5.9e-149 G PTS system mannose/fructose/sorbose family IID component
HFLFIKEJ_02178 3.4e-63 K Transcriptional regulator
HFLFIKEJ_02179 6e-247 ypiB EGP Major facilitator Superfamily
HFLFIKEJ_02180 6.1e-87
HFLFIKEJ_02181 5e-223 dgoD 4.2.1.6 M Mandelate racemase muconate lactonizing enzyme
HFLFIKEJ_02182 5.1e-246 G PTS system sugar-specific permease component
HFLFIKEJ_02183 3.6e-45 sgcB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_02184 5.2e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLFIKEJ_02185 1.2e-109 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HFLFIKEJ_02186 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFLFIKEJ_02187 2.3e-48 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HFLFIKEJ_02188 2.3e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_02189 5.3e-294 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HFLFIKEJ_02190 6.1e-160 ypbG 2.7.1.2 GK ROK family
HFLFIKEJ_02191 1.2e-249 S Metal-independent alpha-mannosidase (GH125)
HFLFIKEJ_02192 0.0 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HFLFIKEJ_02193 2.8e-233 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLFIKEJ_02194 5e-136 K UbiC transcription regulator-associated domain protein
HFLFIKEJ_02195 1.1e-133 fcsR K DeoR C terminal sensor domain
HFLFIKEJ_02196 1.7e-145 4.1.2.17, 4.1.2.19, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HFLFIKEJ_02197 1.6e-76 fucU 5.1.3.29 G RbsD / FucU transport protein family
HFLFIKEJ_02198 1.5e-231 ywtG EGP Major facilitator Superfamily
HFLFIKEJ_02199 1.9e-294 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 2.7.1.51 G FGGY family of carbohydrate kinases, N-terminal domain
HFLFIKEJ_02200 0.0 fucI 5.3.1.25, 5.3.1.3 G Converts the aldose L-fucose into the corresponding ketose L-fuculose
HFLFIKEJ_02201 2e-166 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HFLFIKEJ_02202 1.4e-258 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HFLFIKEJ_02203 3.8e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HFLFIKEJ_02204 4.5e-285 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HFLFIKEJ_02205 5.7e-88 iolF EGP Major facilitator Superfamily
HFLFIKEJ_02206 1.4e-122 iolF EGP Major facilitator Superfamily
HFLFIKEJ_02207 1.4e-192 rhaR K helix_turn_helix, arabinose operon control protein
HFLFIKEJ_02208 6.4e-215 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HFLFIKEJ_02209 4.6e-64 S Protein of unknown function (DUF1093)
HFLFIKEJ_02210 9.5e-95
HFLFIKEJ_02211 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HFLFIKEJ_02212 1.1e-306 plyA3 M Right handed beta helix region
HFLFIKEJ_02213 5e-81
HFLFIKEJ_02214 1.6e-269 M Heparinase II/III N-terminus
HFLFIKEJ_02216 6e-66 G PTS system fructose IIA component
HFLFIKEJ_02217 3.6e-143 agaD G PTS system mannose/fructose/sorbose family IID component
HFLFIKEJ_02218 6.4e-132 G PTS system sorbose-specific iic component
HFLFIKEJ_02219 5.4e-81 agaV 2.7.1.191 G PTS system sorbose subfamily IIB component
HFLFIKEJ_02220 7e-204 ugl 3.2.1.180 GH88 S Glycosyl Hydrolase Family 88
HFLFIKEJ_02221 5.4e-102 Z012_03480 S Psort location Cytoplasmic, score
HFLFIKEJ_02222 1.6e-108 K Bacterial transcriptional regulator
HFLFIKEJ_02223 4.5e-144 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HFLFIKEJ_02224 1e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFLFIKEJ_02225 3e-87 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HFLFIKEJ_02226 3.5e-151 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HFLFIKEJ_02227 5.1e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFLFIKEJ_02228 0.0 CP_0954 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
HFLFIKEJ_02229 9.1e-77 rafA 3.2.1.22 G Melibiase
HFLFIKEJ_02230 2.2e-98 rafA 3.2.1.22 G Melibiase
HFLFIKEJ_02231 7.8e-40 2.7.1.191 G PTS system sorbose subfamily IIB component
HFLFIKEJ_02232 3.1e-65 G PTS system mannose/fructose/sorbose family IID component
HFLFIKEJ_02233 4.4e-64 G PTS system sorbose-specific iic component
HFLFIKEJ_02234 2.1e-22 2.7.1.191 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HFLFIKEJ_02236 4.6e-53 araR K Transcriptional regulator
HFLFIKEJ_02237 1.6e-271 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HFLFIKEJ_02238 6.9e-295 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HFLFIKEJ_02239 1.5e-209 V ABC-type multidrug transport system, ATPase and permease components
HFLFIKEJ_02240 1.1e-108 K Transcriptional activator, Rgg GadR MutR family
HFLFIKEJ_02241 3.3e-86 K Helix-turn-helix domain, rpiR family
HFLFIKEJ_02242 1.5e-10 K Helix-turn-helix domain, rpiR family
HFLFIKEJ_02243 2.1e-82 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFLFIKEJ_02244 1.9e-184 K Helix-turn-helix domain
HFLFIKEJ_02245 6.7e-128 S membrane transporter protein
HFLFIKEJ_02246 2.2e-257 ypiB EGP Major facilitator Superfamily
HFLFIKEJ_02247 1.5e-112 K Transcriptional regulator
HFLFIKEJ_02248 1e-282 M Exporter of polyketide antibiotics
HFLFIKEJ_02249 1.9e-164 yjjC V ABC transporter
HFLFIKEJ_02250 4e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HFLFIKEJ_02251 1e-76 ORF00048
HFLFIKEJ_02252 3.7e-57 K Transcriptional regulator PadR-like family
HFLFIKEJ_02253 1.4e-107 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HFLFIKEJ_02254 1.3e-87 K Acetyltransferase (GNAT) domain
HFLFIKEJ_02255 7.3e-98 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HFLFIKEJ_02256 2.8e-41
HFLFIKEJ_02257 2.2e-241 citM C Citrate transporter
HFLFIKEJ_02258 3.2e-50
HFLFIKEJ_02259 1.1e-36 gcdC 2.3.1.12 I Biotin-requiring enzyme
HFLFIKEJ_02260 1e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
HFLFIKEJ_02262 2.4e-181 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HFLFIKEJ_02263 2.2e-48 citD C Covalent carrier of the coenzyme of citrate lyase
HFLFIKEJ_02264 2.6e-155 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HFLFIKEJ_02265 3.6e-285 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HFLFIKEJ_02266 5.2e-101 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HFLFIKEJ_02267 2.2e-265 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
HFLFIKEJ_02268 7.2e-124 citR K FCD
HFLFIKEJ_02269 9.8e-155 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HFLFIKEJ_02270 7.9e-46
HFLFIKEJ_02271 2.9e-60
HFLFIKEJ_02272 1.2e-81 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFLFIKEJ_02273 1.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFLFIKEJ_02274 1.7e-96 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFLFIKEJ_02275 2.6e-236 pyrP F Permease
HFLFIKEJ_02276 7.3e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HFLFIKEJ_02277 2.1e-238 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFLFIKEJ_02278 1e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HFLFIKEJ_02279 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HFLFIKEJ_02280 4.2e-153 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFLFIKEJ_02281 4.7e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFLFIKEJ_02282 5.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFLFIKEJ_02283 3.2e-193 pfoS S Phosphotransferase system, EIIC
HFLFIKEJ_02284 6.2e-51 S MazG-like family
HFLFIKEJ_02285 0.0 FbpA K Fibronectin-binding protein
HFLFIKEJ_02286 1.3e-06
HFLFIKEJ_02287 3.2e-161 degV S EDD domain protein, DegV family
HFLFIKEJ_02288 1.5e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
HFLFIKEJ_02289 3.3e-208 hisC 2.6.1.9 E Cys/Met metabolism PLP-dependent enzyme
HFLFIKEJ_02290 9.2e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HFLFIKEJ_02291 3.5e-109 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HFLFIKEJ_02292 3.2e-226 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFLFIKEJ_02293 1.7e-09 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HFLFIKEJ_02294 5.9e-103 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HFLFIKEJ_02295 3e-113 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFLFIKEJ_02296 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HFLFIKEJ_02297 1e-131 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HFLFIKEJ_02298 1.4e-56 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HFLFIKEJ_02299 2.3e-51 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HFLFIKEJ_02300 8.3e-207 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFLFIKEJ_02301 3.2e-147 Q Fumarylacetoacetate (FAA) hydrolase family
HFLFIKEJ_02302 7.5e-112 nfnB 1.5.1.34 C Nitroreductase family
HFLFIKEJ_02303 5.9e-70 K Acetyltransferase (GNAT) domain
HFLFIKEJ_02304 7.1e-68 msi198 K Acetyltransferase (GNAT) domain
HFLFIKEJ_02305 3e-218 EGP Transmembrane secretion effector
HFLFIKEJ_02306 1.7e-128 T Transcriptional regulatory protein, C terminal
HFLFIKEJ_02307 2.3e-173 T Histidine kinase-like ATPases
HFLFIKEJ_02308 2.2e-134 XK27_05695 V ABC transporter, ATP-binding protein
HFLFIKEJ_02309 0.0 ysaB V FtsX-like permease family
HFLFIKEJ_02310 5.8e-208 xerS L Belongs to the 'phage' integrase family
HFLFIKEJ_02311 9.5e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
HFLFIKEJ_02312 5.2e-181 K LysR substrate binding domain
HFLFIKEJ_02313 2.1e-170 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFLFIKEJ_02314 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HFLFIKEJ_02315 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFLFIKEJ_02316 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFLFIKEJ_02317 6.9e-110 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFLFIKEJ_02318 6.2e-173 lacX 5.1.3.3 G Aldose 1-epimerase
HFLFIKEJ_02319 2.5e-256 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HFLFIKEJ_02320 5.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HFLFIKEJ_02321 4.7e-168 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HFLFIKEJ_02322 6.1e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HFLFIKEJ_02323 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFLFIKEJ_02324 1.1e-144 dprA LU DNA protecting protein DprA
HFLFIKEJ_02325 9.6e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFLFIKEJ_02326 8.8e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFLFIKEJ_02327 1.6e-126 S Domain of unknown function (DUF4918)
HFLFIKEJ_02329 6.8e-56
HFLFIKEJ_02330 8e-258 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HFLFIKEJ_02331 2.3e-40 yozE S Belongs to the UPF0346 family
HFLFIKEJ_02332 1.8e-95 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFLFIKEJ_02333 2.4e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HFLFIKEJ_02334 7.8e-157 ypmR E GDSL-like Lipase/Acylhydrolase
HFLFIKEJ_02335 6.6e-148 DegV S EDD domain protein, DegV family
HFLFIKEJ_02336 8.1e-114 hly S protein, hemolysin III
HFLFIKEJ_02337 8.8e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFLFIKEJ_02338 4.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFLFIKEJ_02339 0.0 yfmR S ABC transporter, ATP-binding protein
HFLFIKEJ_02340 9.6e-85
HFLFIKEJ_02341 9.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFLFIKEJ_02342 4.8e-149 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFLFIKEJ_02343 2.6e-236 S Tetratricopeptide repeat protein
HFLFIKEJ_02344 2.4e-95 yqeG S HAD phosphatase, family IIIA
HFLFIKEJ_02345 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
HFLFIKEJ_02346 1.1e-47 yhbY J RNA-binding protein
HFLFIKEJ_02347 9.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFLFIKEJ_02348 5.6e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HFLFIKEJ_02349 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFLFIKEJ_02350 7.6e-140 yqeM Q Methyltransferase
HFLFIKEJ_02351 1e-207 ylbM S Belongs to the UPF0348 family
HFLFIKEJ_02352 7.7e-97 yceD S Uncharacterized ACR, COG1399
HFLFIKEJ_02354 7.1e-18 yhcX S Psort location Cytoplasmic, score
HFLFIKEJ_02355 2.2e-58 L Probable transposase
HFLFIKEJ_02356 3.6e-165 L Probable transposase
HFLFIKEJ_02357 5.6e-140 M Peptidase family M23
HFLFIKEJ_02358 7.2e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFLFIKEJ_02359 7.9e-123 K response regulator
HFLFIKEJ_02360 8e-288 arlS 2.7.13.3 T Histidine kinase
HFLFIKEJ_02361 1.3e-179 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFLFIKEJ_02362 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HFLFIKEJ_02363 2.1e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFLFIKEJ_02364 5.6e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFLFIKEJ_02365 6.9e-68 yodB K Transcriptional regulator, HxlR family
HFLFIKEJ_02366 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFLFIKEJ_02367 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFLFIKEJ_02368 6.6e-207 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFLFIKEJ_02369 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HFLFIKEJ_02370 9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFLFIKEJ_02371 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HFLFIKEJ_02372 1.4e-63 S Family of unknown function (DUF5322)
HFLFIKEJ_02373 2.7e-67 rnhA 3.1.26.4 L Ribonuclease HI
HFLFIKEJ_02374 5.7e-109 XK27_02070 S Nitroreductase family
HFLFIKEJ_02375 2.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFLFIKEJ_02376 3.3e-55
HFLFIKEJ_02377 3.1e-270 K Mga helix-turn-helix domain
HFLFIKEJ_02378 4.5e-38 nrdH O Glutaredoxin
HFLFIKEJ_02379 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFLFIKEJ_02380 4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFLFIKEJ_02381 4.5e-163 K Transcriptional regulator
HFLFIKEJ_02382 0.0 pepO 3.4.24.71 O Peptidase family M13
HFLFIKEJ_02383 4.8e-193 lplA 6.3.1.20 H Lipoate-protein ligase
HFLFIKEJ_02384 1.5e-33
HFLFIKEJ_02385 1e-173 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HFLFIKEJ_02386 1.6e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HFLFIKEJ_02388 1.8e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFLFIKEJ_02389 1.2e-105 ypsA S Belongs to the UPF0398 family
HFLFIKEJ_02390 3.3e-120 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFLFIKEJ_02391 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HFLFIKEJ_02392 1.2e-85 comEB 3.5.4.12 F ComE operon protein 2
HFLFIKEJ_02393 2.8e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFLFIKEJ_02394 4e-110 dnaD L DnaD domain protein
HFLFIKEJ_02395 2.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HFLFIKEJ_02396 6.9e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HFLFIKEJ_02397 6.1e-85 ypmB S Protein conserved in bacteria
HFLFIKEJ_02399 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HFLFIKEJ_02400 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HFLFIKEJ_02401 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFLFIKEJ_02402 4.6e-166 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HFLFIKEJ_02403 9.6e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HFLFIKEJ_02404 3.4e-194 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFLFIKEJ_02405 3.5e-260 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HFLFIKEJ_02406 7.2e-175
HFLFIKEJ_02407 5.9e-140
HFLFIKEJ_02408 9.7e-61 yitW S Iron-sulfur cluster assembly protein
HFLFIKEJ_02409 1.9e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HFLFIKEJ_02410 2.9e-114 V (ABC) transporter
HFLFIKEJ_02411 1.7e-143 V (ABC) transporter
HFLFIKEJ_02412 1.3e-307 V ABC transporter transmembrane region
HFLFIKEJ_02413 6.3e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFLFIKEJ_02414 7.1e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
HFLFIKEJ_02415 4.4e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFLFIKEJ_02416 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFLFIKEJ_02417 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HFLFIKEJ_02418 8.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HFLFIKEJ_02419 6.5e-93 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
HFLFIKEJ_02420 1.1e-06 S ABC-2 family transporter protein
HFLFIKEJ_02421 3.7e-123 V ATPases associated with a variety of cellular activities
HFLFIKEJ_02422 3.5e-54
HFLFIKEJ_02423 2.6e-149 recO L Involved in DNA repair and RecF pathway recombination
HFLFIKEJ_02424 1.2e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFLFIKEJ_02425 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HFLFIKEJ_02426 1.5e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HFLFIKEJ_02427 1.4e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFLFIKEJ_02428 7.7e-180 phoH T phosphate starvation-inducible protein PhoH
HFLFIKEJ_02429 8e-68 yqeY S YqeY-like protein
HFLFIKEJ_02430 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HFLFIKEJ_02431 7.2e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HFLFIKEJ_02432 7.9e-168 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HFLFIKEJ_02433 4.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFLFIKEJ_02434 1.1e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HFLFIKEJ_02435 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFLFIKEJ_02436 1.4e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
HFLFIKEJ_02437 3.4e-249 sacA 3.2.1.26 GH32 G Glycosyl hydrolase family 32
HFLFIKEJ_02438 3.4e-180 sacC5 2.7.1.4, 3.2.1.80 G pfkB family carbohydrate kinase
HFLFIKEJ_02439 1.9e-96 maa 2.3.1.79 S Maltose acetyltransferase
HFLFIKEJ_02440 5.7e-65 nrp 1.20.4.1 P ArsC family
HFLFIKEJ_02441 0.0 fbp 3.1.3.11 G phosphatase activity
HFLFIKEJ_02442 2.8e-143 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFLFIKEJ_02443 2.5e-116 ylcC 3.4.22.70 M Sortase family
HFLFIKEJ_02444 3e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HFLFIKEJ_02445 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HFLFIKEJ_02446 1.7e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HFLFIKEJ_02447 7.9e-200 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HFLFIKEJ_02448 3.1e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HFLFIKEJ_02450 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HFLFIKEJ_02451 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HFLFIKEJ_02452 1e-173 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFLFIKEJ_02453 1.4e-53 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HFLFIKEJ_02454 9e-162 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFLFIKEJ_02455 2e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFLFIKEJ_02456 3.6e-123 spl M NlpC/P60 family
HFLFIKEJ_02457 4.3e-64 yugI 5.3.1.9 J general stress protein
HFLFIKEJ_02458 8.5e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFLFIKEJ_02459 3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HFLFIKEJ_02460 1.5e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HFLFIKEJ_02461 8.9e-116 dedA S SNARE-like domain protein
HFLFIKEJ_02462 9.5e-115 S Protein of unknown function (DUF1461)
HFLFIKEJ_02463 4.8e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFLFIKEJ_02464 4e-110 yutD S Protein of unknown function (DUF1027)
HFLFIKEJ_02465 8.3e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HFLFIKEJ_02466 5.9e-114 S Calcineurin-like phosphoesterase
HFLFIKEJ_02467 5.9e-116 yibF S overlaps another CDS with the same product name
HFLFIKEJ_02468 2.9e-188 yibE S overlaps another CDS with the same product name
HFLFIKEJ_02469 2.1e-54
HFLFIKEJ_02470 8.1e-257 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HFLFIKEJ_02471 4.2e-272 pepV 3.5.1.18 E dipeptidase PepV
HFLFIKEJ_02472 1.3e-134 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFLFIKEJ_02473 1.4e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HFLFIKEJ_02474 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HFLFIKEJ_02475 2.3e-179 ccpA K catabolite control protein A
HFLFIKEJ_02476 2.6e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFLFIKEJ_02477 5e-93 niaR S 3H domain
HFLFIKEJ_02478 1.9e-78 ytxH S YtxH-like protein
HFLFIKEJ_02480 1.9e-81 F NUDIX domain
HFLFIKEJ_02481 2.3e-90 S AAA domain
HFLFIKEJ_02482 2.5e-112 ycaC Q Isochorismatase family
HFLFIKEJ_02483 1.5e-253 ydiC1 EGP Major Facilitator Superfamily
HFLFIKEJ_02484 3.5e-211 yeaN P Transporter, major facilitator family protein
HFLFIKEJ_02485 4.3e-172 iolS C Aldo keto reductase
HFLFIKEJ_02486 4.4e-64 manO S Domain of unknown function (DUF956)
HFLFIKEJ_02487 8.7e-170 manN G system, mannose fructose sorbose family IID component
HFLFIKEJ_02488 1.6e-122 manY G PTS system
HFLFIKEJ_02489 1.3e-182 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HFLFIKEJ_02490 9.8e-220 EGP Major facilitator Superfamily
HFLFIKEJ_02491 2.3e-187 K Helix-turn-helix XRE-family like proteins
HFLFIKEJ_02492 4.2e-150 K Helix-turn-helix XRE-family like proteins
HFLFIKEJ_02493 1.3e-157 K sequence-specific DNA binding
HFLFIKEJ_02497 1.6e-304 ybfG M peptidoglycan-binding domain-containing protein
HFLFIKEJ_02498 4e-287 glnP P ABC transporter permease
HFLFIKEJ_02499 4.1e-133 glnQ E ABC transporter, ATP-binding protein
HFLFIKEJ_02500 2e-40
HFLFIKEJ_02501 1.5e-236 malE G Bacterial extracellular solute-binding protein
HFLFIKEJ_02502 1e-09
HFLFIKEJ_02503 6.3e-123 S Protein of unknown function (DUF975)
HFLFIKEJ_02504 1.5e-58 yqkB S Iron-sulphur cluster biosynthesis
HFLFIKEJ_02505 1.2e-52
HFLFIKEJ_02506 1.9e-80 S Bacterial PH domain
HFLFIKEJ_02507 9.4e-286 ydbT S Bacterial PH domain
HFLFIKEJ_02508 1.3e-142 S AAA ATPase domain
HFLFIKEJ_02509 1e-164 yniA G Phosphotransferase enzyme family
HFLFIKEJ_02510 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFLFIKEJ_02511 2.7e-255 glnP P ABC transporter
HFLFIKEJ_02512 1.1e-264 glnP P ABC transporter
HFLFIKEJ_02513 3.4e-100 ydaF J Acetyltransferase (GNAT) domain
HFLFIKEJ_02514 6.3e-103 S Stage II sporulation protein M
HFLFIKEJ_02515 3.2e-167 yeaC S ATPase family associated with various cellular activities (AAA)
HFLFIKEJ_02516 1e-131 yeaD S Protein of unknown function DUF58
HFLFIKEJ_02517 0.0 yebA E Transglutaminase/protease-like homologues
HFLFIKEJ_02518 2.8e-12
HFLFIKEJ_02519 7e-214 lsgC M Glycosyl transferases group 1
HFLFIKEJ_02520 1.3e-254 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HFLFIKEJ_02521 9e-112 S Bacteriocin-protection, YdeI or OmpD-Associated
HFLFIKEJ_02522 5.1e-56 yjdF S Protein of unknown function (DUF2992)
HFLFIKEJ_02525 1.3e-96
HFLFIKEJ_02527 2.7e-149 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
HFLFIKEJ_02528 7.2e-68
HFLFIKEJ_02529 1.6e-131 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
HFLFIKEJ_02530 2e-169 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HFLFIKEJ_02531 1.6e-226 ptsG G phosphotransferase system
HFLFIKEJ_02532 4e-100 K CAT RNA binding domain
HFLFIKEJ_02534 8.8e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFLFIKEJ_02535 5.5e-180 D Alpha beta
HFLFIKEJ_02536 5.9e-185 lipA I Carboxylesterase family
HFLFIKEJ_02537 3.9e-215 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HFLFIKEJ_02538 1e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFLFIKEJ_02539 0.0 mtlR K Mga helix-turn-helix domain
HFLFIKEJ_02540 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HFLFIKEJ_02541 9.6e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFLFIKEJ_02542 8.6e-150 S haloacid dehalogenase-like hydrolase
HFLFIKEJ_02543 2.8e-44
HFLFIKEJ_02544 2e-14
HFLFIKEJ_02545 1.3e-137
HFLFIKEJ_02546 8.2e-221 spiA K IrrE N-terminal-like domain
HFLFIKEJ_02547 8.1e-151 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFLFIKEJ_02548 1e-125 V ABC transporter
HFLFIKEJ_02549 8.1e-208 bacI V MacB-like periplasmic core domain
HFLFIKEJ_02550 1.3e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFLFIKEJ_02551 2.3e-147
HFLFIKEJ_02552 1.5e-123 S Tetratricopeptide repeat
HFLFIKEJ_02553 1.7e-122
HFLFIKEJ_02554 3e-72
HFLFIKEJ_02555 3.3e-42 rpmE2 J Ribosomal protein L31
HFLFIKEJ_02556 7.4e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFLFIKEJ_02557 6.4e-08
HFLFIKEJ_02559 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFLFIKEJ_02560 7e-220 ndh 1.6.99.3 C NADH dehydrogenase
HFLFIKEJ_02563 3e-151 S Protein of unknown function (DUF1211)
HFLFIKEJ_02564 5.9e-62 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFLFIKEJ_02565 3.5e-79 ywiB S Domain of unknown function (DUF1934)
HFLFIKEJ_02566 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HFLFIKEJ_02567 9.6e-266 ywfO S HD domain protein
HFLFIKEJ_02568 2.4e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
HFLFIKEJ_02569 4.2e-176 S DUF218 domain
HFLFIKEJ_02570 1.8e-60 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFLFIKEJ_02571 4.3e-74
HFLFIKEJ_02572 1e-51 nudA S ASCH
HFLFIKEJ_02573 1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFLFIKEJ_02574 1.7e-212 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFLFIKEJ_02575 1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFLFIKEJ_02576 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFLFIKEJ_02577 4e-53
HFLFIKEJ_02578 5.8e-124 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFLFIKEJ_02579 3e-173 prmA J Ribosomal protein L11 methyltransferase
HFLFIKEJ_02580 3.6e-85 XK27_03960 S Protein of unknown function (DUF3013)
HFLFIKEJ_02581 9.4e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HFLFIKEJ_02582 3.1e-37
HFLFIKEJ_02583 9.7e-62 S Protein of unknown function (DUF1093)
HFLFIKEJ_02584 8.9e-26
HFLFIKEJ_02585 3.2e-61
HFLFIKEJ_02587 6.9e-18 M Host cell surface-exposed lipoprotein
HFLFIKEJ_02588 2.2e-145 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
HFLFIKEJ_02589 1.2e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HFLFIKEJ_02590 3.7e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFLFIKEJ_02591 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFLFIKEJ_02592 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HFLFIKEJ_02593 7.1e-62
HFLFIKEJ_02594 1.4e-81 6.3.3.2 S ASCH
HFLFIKEJ_02595 5.9e-32
HFLFIKEJ_02596 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFLFIKEJ_02597 4.1e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFLFIKEJ_02598 1e-286 dnaK O Heat shock 70 kDa protein
HFLFIKEJ_02599 1.4e-99 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFLFIKEJ_02600 8.4e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFLFIKEJ_02601 1.7e-223 hemN H Involved in the biosynthesis of porphyrin-containing compound
HFLFIKEJ_02602 2.5e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HFLFIKEJ_02603 8.1e-160 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFLFIKEJ_02604 5.7e-118 terC P membrane
HFLFIKEJ_02605 7.8e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFLFIKEJ_02606 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFLFIKEJ_02607 5.4e-44 ylxQ J ribosomal protein
HFLFIKEJ_02608 1.5e-46 ylxR K Protein of unknown function (DUF448)
HFLFIKEJ_02609 2.5e-196 nusA K Participates in both transcription termination and antitermination
HFLFIKEJ_02610 1e-84 rimP J Required for maturation of 30S ribosomal subunits
HFLFIKEJ_02611 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFLFIKEJ_02612 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFLFIKEJ_02613 1e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HFLFIKEJ_02614 4.3e-141 cdsA 2.7.7.41 S Belongs to the CDS family
HFLFIKEJ_02615 9.5e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFLFIKEJ_02616 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFLFIKEJ_02617 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HFLFIKEJ_02618 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFLFIKEJ_02619 1.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HFLFIKEJ_02620 4.9e-47 yazA L GIY-YIG catalytic domain protein
HFLFIKEJ_02621 4.8e-134 yabB 2.1.1.223 L Methyltransferase small domain
HFLFIKEJ_02622 2.2e-122 plsC 2.3.1.51 I Acyltransferase
HFLFIKEJ_02623 6.6e-201 bcaP E Amino Acid
HFLFIKEJ_02624 2.9e-137 yejC S Protein of unknown function (DUF1003)
HFLFIKEJ_02625 0.0 mdlB V ABC transporter
HFLFIKEJ_02626 0.0 mdlA V ABC transporter
HFLFIKEJ_02627 4.8e-29 yneF S UPF0154 protein
HFLFIKEJ_02628 1.1e-37 ynzC S UPF0291 protein
HFLFIKEJ_02629 1.1e-25
HFLFIKEJ_02630 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFLFIKEJ_02631 3.1e-147 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HFLFIKEJ_02632 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFLFIKEJ_02633 8.4e-38 ylqC S Belongs to the UPF0109 family
HFLFIKEJ_02634 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HFLFIKEJ_02635 1.2e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFLFIKEJ_02636 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFLFIKEJ_02637 1.8e-24
HFLFIKEJ_02638 8.8e-53
HFLFIKEJ_02639 9.8e-183 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFLFIKEJ_02640 0.0 smc D Required for chromosome condensation and partitioning
HFLFIKEJ_02641 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFLFIKEJ_02642 0.0 oppA1 E ABC transporter substrate-binding protein
HFLFIKEJ_02643 8.2e-136 oppC EP Binding-protein-dependent transport system inner membrane component
HFLFIKEJ_02644 2.8e-174 oppB P ABC transporter permease
HFLFIKEJ_02645 9.1e-150 oppF P Belongs to the ABC transporter superfamily
HFLFIKEJ_02646 4.4e-194 oppD P Belongs to the ABC transporter superfamily
HFLFIKEJ_02647 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFLFIKEJ_02648 4e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFLFIKEJ_02649 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFLFIKEJ_02650 1e-285 yloV S DAK2 domain fusion protein YloV
HFLFIKEJ_02651 2.3e-57 asp S Asp23 family, cell envelope-related function
HFLFIKEJ_02652 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HFLFIKEJ_02653 3.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HFLFIKEJ_02654 1.5e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HFLFIKEJ_02655 8.9e-150 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFLFIKEJ_02656 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HFLFIKEJ_02657 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFLFIKEJ_02658 8.5e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFLFIKEJ_02659 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFLFIKEJ_02660 5.9e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFLFIKEJ_02661 9.1e-245 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFLFIKEJ_02662 6.1e-82 yabR J RNA binding
HFLFIKEJ_02663 4.4e-65 divIC D cell cycle
HFLFIKEJ_02664 1.8e-38 yabO J S4 domain protein
HFLFIKEJ_02665 4.2e-281 yabM S Polysaccharide biosynthesis protein
HFLFIKEJ_02666 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFLFIKEJ_02667 2.4e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFLFIKEJ_02668 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFLFIKEJ_02669 5.9e-263 S Putative peptidoglycan binding domain
HFLFIKEJ_02670 1.3e-96 padR K Transcriptional regulator PadR-like family
HFLFIKEJ_02671 2.4e-246 XK27_06930 S ABC-2 family transporter protein
HFLFIKEJ_02672 9.9e-114 1.6.5.2 S Flavodoxin-like fold
HFLFIKEJ_02673 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HFLFIKEJ_02674 2e-32
HFLFIKEJ_02675 1.2e-103 tag 3.2.2.20 L glycosylase
HFLFIKEJ_02676 4.8e-205 yceJ EGP Major facilitator Superfamily
HFLFIKEJ_02677 1.2e-48 K Helix-turn-helix domain
HFLFIKEJ_02678 7e-29
HFLFIKEJ_02679 6.5e-28 relB L RelB antitoxin
HFLFIKEJ_02680 2.2e-252 L Exonuclease
HFLFIKEJ_02681 5.2e-55
HFLFIKEJ_02683 2.9e-12
HFLFIKEJ_02684 1.9e-20
HFLFIKEJ_02685 2.6e-76 ohr O OsmC-like protein
HFLFIKEJ_02686 1.6e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HFLFIKEJ_02687 2.5e-101 dhaL 2.7.1.121 S Dak2
HFLFIKEJ_02688 9.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
HFLFIKEJ_02689 4e-104 K Bacterial regulatory proteins, tetR family
HFLFIKEJ_02690 9.4e-17
HFLFIKEJ_02691 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HFLFIKEJ_02692 2.5e-175
HFLFIKEJ_02693 3.2e-189 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HFLFIKEJ_02694 8.5e-151 metQ_4 P Belongs to the nlpA lipoprotein family
HFLFIKEJ_02696 5.6e-112 tag 3.2.2.20 L glycosylase
HFLFIKEJ_02697 5.7e-161 yicL EG EamA-like transporter family
HFLFIKEJ_02698 2.7e-24
HFLFIKEJ_02699 4.9e-87
HFLFIKEJ_02700 4.6e-38
HFLFIKEJ_02701 4.7e-172 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HFLFIKEJ_02702 5.3e-237 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HFLFIKEJ_02703 1.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
HFLFIKEJ_02704 5e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HFLFIKEJ_02705 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HFLFIKEJ_02706 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HFLFIKEJ_02707 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HFLFIKEJ_02708 3.2e-164 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFLFIKEJ_02709 4.8e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFLFIKEJ_02710 6.6e-114 S CRISPR-associated protein (Cas_Csn2)
HFLFIKEJ_02711 4.1e-20 XK27_02675 K Acetyltransferase GNAT Family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)