ORF_ID e_value Gene_name EC_number CAZy COGs Description
KCCAKOOK_00001 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCCAKOOK_00002 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCCAKOOK_00003 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCCAKOOK_00004 2.9e-68 S cog cog4699
KCCAKOOK_00005 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCCAKOOK_00006 5.3e-44 cglB NU type II secretion system
KCCAKOOK_00007 2.8e-91 cglB NU type II secretion system
KCCAKOOK_00008 9.4e-42 comGC U Required for transformation and DNA binding
KCCAKOOK_00009 1.8e-57 cglD NU Competence protein
KCCAKOOK_00010 1.4e-15 NU Type II secretory pathway pseudopilin
KCCAKOOK_00011 1.5e-71 comGF U Competence protein ComGF
KCCAKOOK_00012 1.1e-11 comGF U Putative Competence protein ComGF
KCCAKOOK_00013 5.9e-177 ytxK 2.1.1.72 L DNA methylase
KCCAKOOK_00014 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCCAKOOK_00015 8.8e-27 lanR K sequence-specific DNA binding
KCCAKOOK_00016 1.4e-33 V CAAX protease self-immunity
KCCAKOOK_00017 1.1e-66 V CAAX protease self-immunity
KCCAKOOK_00019 1.8e-111 S CAAX amino terminal protease family protein
KCCAKOOK_00020 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCCAKOOK_00021 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KCCAKOOK_00022 4.1e-09 S Domain of unknown function (DUF4651)
KCCAKOOK_00023 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KCCAKOOK_00024 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCCAKOOK_00025 3.9e-16 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KCCAKOOK_00026 4.7e-120 yqfA K protein, Hemolysin III
KCCAKOOK_00027 1.5e-118 yqfA K protein, Hemolysin III
KCCAKOOK_00028 1e-25 K hmm pf08876
KCCAKOOK_00029 7.9e-17 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KCCAKOOK_00030 2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KCCAKOOK_00031 8.1e-41 S Protein of unknown function (DUF1697)
KCCAKOOK_00032 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KCCAKOOK_00033 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
KCCAKOOK_00034 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KCCAKOOK_00035 3.3e-158 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KCCAKOOK_00036 3.7e-73 argR K Regulates arginine biosynthesis genes
KCCAKOOK_00037 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
KCCAKOOK_00038 3e-148 DegV S DegV family
KCCAKOOK_00039 3.9e-143 ypmR E lipolytic protein G-D-S-L family
KCCAKOOK_00040 1.7e-83 ypmS S Protein conserved in bacteria
KCCAKOOK_00041 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KCCAKOOK_00043 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KCCAKOOK_00044 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KCCAKOOK_00045 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCCAKOOK_00046 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KCCAKOOK_00047 2.5e-43 ysdA L Membrane
KCCAKOOK_00048 2.6e-274 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCCAKOOK_00049 9.2e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCCAKOOK_00050 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
KCCAKOOK_00051 0.0 dnaE 2.7.7.7 L DNA polymerase
KCCAKOOK_00052 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KCCAKOOK_00053 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KCCAKOOK_00054 7.9e-39 ptsH G phosphocarrier protein Hpr
KCCAKOOK_00055 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
KCCAKOOK_00056 6.7e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
KCCAKOOK_00057 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCCAKOOK_00058 2.2e-34 nrdH O Glutaredoxin
KCCAKOOK_00059 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCCAKOOK_00060 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCCAKOOK_00062 4.2e-71 L Transposase (IS116 IS110 IS902 family)
KCCAKOOK_00063 3.3e-26 L Transposase (IS116 IS110 IS902 family)
KCCAKOOK_00064 5.3e-165 ypuA S secreted protein
KCCAKOOK_00065 1.6e-54 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
KCCAKOOK_00066 6e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KCCAKOOK_00067 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCCAKOOK_00068 3.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KCCAKOOK_00069 2.8e-257 noxE P NADH oxidase
KCCAKOOK_00070 1.9e-294 yfmM S abc transporter atp-binding protein
KCCAKOOK_00071 2.6e-180 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KCCAKOOK_00072 6e-60 spd F DNA RNA non-specific endonuclease
KCCAKOOK_00073 1.5e-92 lemA S LemA family
KCCAKOOK_00074 1.9e-223 EGP Major facilitator Superfamily
KCCAKOOK_00075 9.1e-72 adcR K transcriptional
KCCAKOOK_00076 6.4e-136 adcC P ABC transporter, ATP-binding protein
KCCAKOOK_00077 5.4e-131 adcB P ABC transporter (Permease
KCCAKOOK_00078 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KCCAKOOK_00079 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
KCCAKOOK_00080 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
KCCAKOOK_00081 1.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KCCAKOOK_00082 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
KCCAKOOK_00083 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
KCCAKOOK_00084 1.9e-127 yeeN K transcriptional regulatory protein
KCCAKOOK_00085 9.8e-50 yajC U protein transport
KCCAKOOK_00086 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCCAKOOK_00087 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KCCAKOOK_00088 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KCCAKOOK_00089 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KCCAKOOK_00090 0.0 WQ51_06230 S ABC transporter substrate binding protein
KCCAKOOK_00091 5.2e-142 cmpC S abc transporter atp-binding protein
KCCAKOOK_00092 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KCCAKOOK_00093 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KCCAKOOK_00094 6.4e-18 L transposase activity
KCCAKOOK_00095 8.4e-10
KCCAKOOK_00096 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KCCAKOOK_00097 2.5e-134 divIVA D Cell division protein DivIVA
KCCAKOOK_00098 6.1e-143 ylmH T S4 RNA-binding domain
KCCAKOOK_00099 2.6e-34 yggT D integral membrane protein
KCCAKOOK_00100 6.8e-96 sepF D cell septum assembly
KCCAKOOK_00101 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCCAKOOK_00102 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCCAKOOK_00103 6.8e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KCCAKOOK_00104 3.1e-169 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KCCAKOOK_00105 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCCAKOOK_00106 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KCCAKOOK_00108 0.0 typA T GTP-binding protein TypA
KCCAKOOK_00109 2.2e-179 glk 2.7.1.2 G Glucokinase
KCCAKOOK_00110 8.4e-28 yqgQ S protein conserved in bacteria
KCCAKOOK_00111 1.1e-80 perR P Belongs to the Fur family
KCCAKOOK_00112 1.8e-90 dps P Belongs to the Dps family
KCCAKOOK_00113 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KCCAKOOK_00114 2.9e-185 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KCCAKOOK_00115 1.1e-27 Q the current gene model (or a revised gene model) may contain a frame shift
KCCAKOOK_00116 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
KCCAKOOK_00118 3.2e-17 S Domain of unknown function (DUF4649)
KCCAKOOK_00119 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
KCCAKOOK_00120 2e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KCCAKOOK_00121 4.4e-135 XK27_08845 S abc transporter atp-binding protein
KCCAKOOK_00122 4.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCCAKOOK_00123 3.5e-151 estA CE1 S Putative esterase
KCCAKOOK_00124 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
KCCAKOOK_00126 2.3e-75 fld C Flavodoxin
KCCAKOOK_00127 6.4e-282 clcA P Chloride transporter, ClC family
KCCAKOOK_00128 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KCCAKOOK_00129 2.8e-219 XK27_05110 P chloride
KCCAKOOK_00130 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KCCAKOOK_00133 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
KCCAKOOK_00134 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCCAKOOK_00135 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KCCAKOOK_00136 9.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCCAKOOK_00137 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KCCAKOOK_00138 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCCAKOOK_00139 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCCAKOOK_00140 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCCAKOOK_00141 8.3e-23
KCCAKOOK_00142 4.8e-88 oppF P Belongs to the ABC transporter superfamily
KCCAKOOK_00143 2.6e-62 oppF P Belongs to the ABC transporter superfamily
KCCAKOOK_00144 4.6e-57 oppD P Belongs to the ABC transporter superfamily
KCCAKOOK_00145 6.8e-28 oppD P Belongs to the ABC transporter superfamily
KCCAKOOK_00146 2.5e-32 oppD P Belongs to the ABC transporter superfamily
KCCAKOOK_00147 3e-27 oppD P Belongs to the ABC transporter superfamily
KCCAKOOK_00148 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCCAKOOK_00149 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCCAKOOK_00150 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCCAKOOK_00151 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCCAKOOK_00152 3e-139 oppA E ABC transporter substrate-binding protein
KCCAKOOK_00153 9.7e-19 oppA E ABC transporter substrate-binding protein
KCCAKOOK_00154 2.2e-273 sufB O assembly protein SufB
KCCAKOOK_00155 9.5e-74 nifU C SUF system FeS assembly protein, NifU family
KCCAKOOK_00156 2.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCCAKOOK_00157 1.4e-234 sufD O assembly protein SufD
KCCAKOOK_00158 3.6e-143 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KCCAKOOK_00159 1.9e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
KCCAKOOK_00160 2.6e-135 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KCCAKOOK_00161 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KCCAKOOK_00162 5.8e-275 glnP P ABC transporter
KCCAKOOK_00163 1e-123 glnQ E abc transporter atp-binding protein
KCCAKOOK_00164 5e-94 V VanZ like family
KCCAKOOK_00165 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KCCAKOOK_00166 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
KCCAKOOK_00167 2e-45 rpmE2 J 50S ribosomal protein L31
KCCAKOOK_00168 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KCCAKOOK_00169 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KCCAKOOK_00170 8.9e-155 gst O Glutathione S-transferase
KCCAKOOK_00171 9.8e-129 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KCCAKOOK_00172 1.6e-45 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KCCAKOOK_00173 3.5e-111 tdk 2.7.1.21 F thymidine kinase
KCCAKOOK_00174 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCCAKOOK_00175 4.7e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KCCAKOOK_00176 2.8e-108 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KCCAKOOK_00177 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCCAKOOK_00178 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
KCCAKOOK_00179 8e-100 pvaA M lytic transglycosylase activity
KCCAKOOK_00180 0.0 yfiB1 V abc transporter atp-binding protein
KCCAKOOK_00181 0.0 XK27_10035 V abc transporter atp-binding protein
KCCAKOOK_00182 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
KCCAKOOK_00183 3.2e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCCAKOOK_00184 3.9e-237 dltB M Membrane protein involved in D-alanine export
KCCAKOOK_00185 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCCAKOOK_00186 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KCCAKOOK_00187 1.5e-30 L Integrase core domain protein
KCCAKOOK_00189 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCCAKOOK_00190 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KCCAKOOK_00191 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KCCAKOOK_00192 6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCCAKOOK_00193 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KCCAKOOK_00194 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KCCAKOOK_00195 2e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KCCAKOOK_00196 1.1e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KCCAKOOK_00197 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCCAKOOK_00198 5.9e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
KCCAKOOK_00199 4e-238 rodA D Belongs to the SEDS family
KCCAKOOK_00200 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCCAKOOK_00201 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KCCAKOOK_00202 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KCCAKOOK_00203 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KCCAKOOK_00204 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KCCAKOOK_00205 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCCAKOOK_00206 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCCAKOOK_00207 3.8e-125 dnaD
KCCAKOOK_00208 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCCAKOOK_00212 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
KCCAKOOK_00213 6.4e-108 S Domain of unknown function (DUF1803)
KCCAKOOK_00214 7.8e-102 ygaC J Belongs to the UPF0374 family
KCCAKOOK_00215 4.4e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
KCCAKOOK_00216 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCCAKOOK_00217 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
KCCAKOOK_00218 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
KCCAKOOK_00219 4.3e-115 S Haloacid dehalogenase-like hydrolase
KCCAKOOK_00220 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KCCAKOOK_00221 4e-72 marR K Transcriptional regulator, MarR family
KCCAKOOK_00222 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCCAKOOK_00223 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCCAKOOK_00224 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KCCAKOOK_00225 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KCCAKOOK_00226 1.6e-126 IQ reductase
KCCAKOOK_00227 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KCCAKOOK_00228 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KCCAKOOK_00229 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KCCAKOOK_00230 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KCCAKOOK_00231 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCCAKOOK_00232 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KCCAKOOK_00233 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KCCAKOOK_00234 3.8e-10 tnp L Transposase
KCCAKOOK_00235 8e-114 tnp L Transposase
KCCAKOOK_00237 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
KCCAKOOK_00238 2.8e-282 T PhoQ Sensor
KCCAKOOK_00239 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCCAKOOK_00240 8.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
KCCAKOOK_00241 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KCCAKOOK_00242 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
KCCAKOOK_00243 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
KCCAKOOK_00244 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
KCCAKOOK_00245 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KCCAKOOK_00246 2e-149 cbiQ P cobalt transport
KCCAKOOK_00247 0.0 ykoD P abc transporter atp-binding protein
KCCAKOOK_00248 8e-94 S UPF0397 protein
KCCAKOOK_00249 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KCCAKOOK_00250 5.1e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KCCAKOOK_00251 5.2e-98 metI P ABC transporter (Permease
KCCAKOOK_00252 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCCAKOOK_00253 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KCCAKOOK_00254 6e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KCCAKOOK_00255 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KCCAKOOK_00256 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
KCCAKOOK_00257 0.0 S Lantibiotic dehydratase, C terminus
KCCAKOOK_00258 3.9e-46 S Lantibiotic dehydratase, C terminus
KCCAKOOK_00260 1.5e-35 K sequence-specific DNA binding
KCCAKOOK_00261 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KCCAKOOK_00262 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KCCAKOOK_00263 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCCAKOOK_00264 1.8e-31 K helix-turn-helix
KCCAKOOK_00265 3.7e-154 degV S DegV family
KCCAKOOK_00266 7e-92 yacP S RNA-binding protein containing a PIN domain
KCCAKOOK_00267 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCCAKOOK_00270 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KCCAKOOK_00271 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCCAKOOK_00272 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
KCCAKOOK_00273 1.7e-142 S SseB protein N-terminal domain
KCCAKOOK_00274 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KCCAKOOK_00275 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCCAKOOK_00276 9.3e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCCAKOOK_00277 1.7e-125 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCCAKOOK_00278 0.0 clpC O Belongs to the ClpA ClpB family
KCCAKOOK_00279 6.2e-76 ctsR K Belongs to the CtsR family
KCCAKOOK_00280 9.3e-83 S Putative small multi-drug export protein
KCCAKOOK_00281 4e-84 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCCAKOOK_00282 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KCCAKOOK_00283 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
KCCAKOOK_00284 1.6e-202 arcT 2.6.1.1 E Aminotransferase
KCCAKOOK_00285 2.5e-136 ET ABC transporter
KCCAKOOK_00286 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
KCCAKOOK_00287 2.9e-84 mutT 3.6.1.55 F Nudix family
KCCAKOOK_00288 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KCCAKOOK_00290 1.2e-55 V CAAX protease self-immunity
KCCAKOOK_00291 7.6e-32 S CAAX amino terminal protease family protein
KCCAKOOK_00292 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KCCAKOOK_00293 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCCAKOOK_00294 2.4e-16 XK27_00735
KCCAKOOK_00295 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCCAKOOK_00297 6.2e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCCAKOOK_00300 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
KCCAKOOK_00301 4.7e-51 ycaO O OsmC-like protein
KCCAKOOK_00303 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
KCCAKOOK_00305 8.2e-48 dnaQ 2.7.7.7 L DNA polymerase III
KCCAKOOK_00306 9.2e-122 K transcriptional regulator, MerR family
KCCAKOOK_00307 5.1e-47 L transposase activity
KCCAKOOK_00308 7e-32 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KCCAKOOK_00309 1.6e-27
KCCAKOOK_00310 0.0 ctpE P E1-E2 ATPase
KCCAKOOK_00311 1.4e-54
KCCAKOOK_00312 1.8e-41 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
KCCAKOOK_00313 2.9e-254 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCCAKOOK_00314 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KCCAKOOK_00315 5.1e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCCAKOOK_00316 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KCCAKOOK_00317 5.5e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KCCAKOOK_00318 2.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KCCAKOOK_00319 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KCCAKOOK_00320 2.7e-73 copY K Copper transport repressor, CopY TcrY family
KCCAKOOK_00321 0.0 copA 3.6.3.54 P P-type ATPase
KCCAKOOK_00322 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
KCCAKOOK_00323 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KCCAKOOK_00324 3.3e-133 V ATPase activity
KCCAKOOK_00325 2.8e-120 skfE V abc transporter atp-binding protein
KCCAKOOK_00326 8.6e-63 yvoA_1 K Transcriptional
KCCAKOOK_00327 4.8e-148 supH S overlaps another CDS with the same product name
KCCAKOOK_00328 6.9e-150 XK27_02985 S overlaps another CDS with the same product name
KCCAKOOK_00329 1.1e-211 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KCCAKOOK_00330 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KCCAKOOK_00331 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KCCAKOOK_00332 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCCAKOOK_00333 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCCAKOOK_00334 6.8e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCCAKOOK_00335 2e-132 stp 3.1.3.16 T phosphatase
KCCAKOOK_00336 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KCCAKOOK_00337 3.7e-120 yvqF KT membrane
KCCAKOOK_00338 1.7e-174 vraS 2.7.13.3 T Histidine kinase
KCCAKOOK_00339 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KCCAKOOK_00340 4.2e-44 yrzB S Belongs to the UPF0473 family
KCCAKOOK_00341 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCCAKOOK_00342 2.8e-44 yrzL S Belongs to the UPF0297 family
KCCAKOOK_00343 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KCCAKOOK_00344 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KCCAKOOK_00346 3.5e-216 int L Belongs to the 'phage' integrase family
KCCAKOOK_00347 1.9e-18 S Domain of unknown function (DUF3173)
KCCAKOOK_00348 1.4e-107 L Replication initiation factor
KCCAKOOK_00349 1.3e-36 L Replication initiation factor
KCCAKOOK_00350 2.5e-89 K sequence-specific DNA binding
KCCAKOOK_00351 3.9e-287 V ABC transporter transmembrane region
KCCAKOOK_00352 1.3e-190 C Radical SAM
KCCAKOOK_00353 6.3e-16 C Radical SAM
KCCAKOOK_00355 1.4e-127 Z012_04635 K sequence-specific DNA binding
KCCAKOOK_00356 2.1e-280 V ABC transporter
KCCAKOOK_00357 0.0 KLT serine threonine protein kinase
KCCAKOOK_00358 3.8e-154 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCCAKOOK_00360 1.8e-133 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCCAKOOK_00361 1e-13 rpmH J Ribosomal protein L34
KCCAKOOK_00362 1.3e-185 jag S RNA-binding protein
KCCAKOOK_00363 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCCAKOOK_00364 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KCCAKOOK_00365 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
KCCAKOOK_00366 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KCCAKOOK_00367 1.3e-281 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCCAKOOK_00368 6.7e-81 amiA E transmembrane transport
KCCAKOOK_00369 7.3e-69 amiA E transmembrane transport
KCCAKOOK_00370 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KCCAKOOK_00371 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCCAKOOK_00372 4.6e-50 S Protein of unknown function (DUF3397)
KCCAKOOK_00373 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KCCAKOOK_00374 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
KCCAKOOK_00375 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
KCCAKOOK_00376 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KCCAKOOK_00377 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KCCAKOOK_00378 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
KCCAKOOK_00379 4.3e-77 XK27_09620 S reductase
KCCAKOOK_00380 3e-13
KCCAKOOK_00381 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KCCAKOOK_00382 1e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KCCAKOOK_00383 8.4e-122 comFC S Competence protein
KCCAKOOK_00384 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KCCAKOOK_00385 6.3e-111 yvyE 3.4.13.9 S YigZ family
KCCAKOOK_00386 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KCCAKOOK_00387 3.3e-43 acuB S IMP dehydrogenase activity
KCCAKOOK_00388 2.8e-70 acuB S IMP dehydrogenase activity
KCCAKOOK_00389 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KCCAKOOK_00390 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KCCAKOOK_00391 1.6e-137 livM E Belongs to the binding-protein-dependent transport system permease family
KCCAKOOK_00392 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KCCAKOOK_00393 5.9e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KCCAKOOK_00394 7.1e-46 ylbG S UPF0298 protein
KCCAKOOK_00395 1.2e-74 ylbF S Belongs to the UPF0342 family
KCCAKOOK_00396 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KCCAKOOK_00397 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCCAKOOK_00400 1.1e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KCCAKOOK_00401 6.1e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
KCCAKOOK_00402 5.3e-41 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KCCAKOOK_00403 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
KCCAKOOK_00404 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
KCCAKOOK_00405 1.1e-109 6.3.2.2 H ergothioneine biosynthetic process
KCCAKOOK_00407 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
KCCAKOOK_00408 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KCCAKOOK_00410 5.7e-217 S MvaI/BcnI restriction endonuclease family
KCCAKOOK_00412 7.7e-13
KCCAKOOK_00413 5e-31 S Hypothetical protein (DUF2513)
KCCAKOOK_00414 6.5e-31
KCCAKOOK_00415 1e-39
KCCAKOOK_00420 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
KCCAKOOK_00421 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KCCAKOOK_00422 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
KCCAKOOK_00423 3.3e-46 K Putative DNA-binding domain
KCCAKOOK_00424 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KCCAKOOK_00425 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KCCAKOOK_00426 5.1e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
KCCAKOOK_00427 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KCCAKOOK_00428 0.0 uup S abc transporter atp-binding protein
KCCAKOOK_00429 6.3e-13 MA20_06245 S yiaA/B two helix domain
KCCAKOOK_00430 8.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
KCCAKOOK_00431 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCCAKOOK_00432 8.7e-150 cobQ S glutamine amidotransferase
KCCAKOOK_00433 6.3e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KCCAKOOK_00434 1.4e-122 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KCCAKOOK_00435 2.5e-167 ybbR S Protein conserved in bacteria
KCCAKOOK_00436 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCCAKOOK_00437 1.7e-70 gtrA S GtrA-like protein
KCCAKOOK_00438 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KCCAKOOK_00439 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KCCAKOOK_00440 2.6e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
KCCAKOOK_00441 1.1e-206 yurR 1.4.5.1 E oxidoreductase
KCCAKOOK_00442 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCCAKOOK_00443 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KCCAKOOK_00445 2.2e-90 S MucBP domain
KCCAKOOK_00446 1.9e-49 M YSIRK type signal peptide
KCCAKOOK_00447 0.0 M the current gene model (or a revised gene model) may contain a
KCCAKOOK_00449 0.0 mdlB V abc transporter atp-binding protein
KCCAKOOK_00450 0.0 lmrA V abc transporter atp-binding protein
KCCAKOOK_00451 1.3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCCAKOOK_00452 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KCCAKOOK_00453 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KCCAKOOK_00454 2.5e-132 rr02 KT response regulator
KCCAKOOK_00455 5.3e-217 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KCCAKOOK_00456 2.8e-168 V ABC transporter
KCCAKOOK_00457 5.4e-122 sagI S ABC-2 type transporter
KCCAKOOK_00458 1e-195 yceA S Belongs to the UPF0176 family
KCCAKOOK_00459 1.9e-22
KCCAKOOK_00460 1.4e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
KCCAKOOK_00461 2.5e-113 S VIT family
KCCAKOOK_00462 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCCAKOOK_00463 2.4e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KCCAKOOK_00464 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
KCCAKOOK_00465 2e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KCCAKOOK_00466 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCCAKOOK_00467 8.8e-104 GBS0088 J protein conserved in bacteria
KCCAKOOK_00468 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KCCAKOOK_00469 1.8e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KCCAKOOK_00470 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
KCCAKOOK_00471 1.6e-77 sigH K DNA-templated transcription, initiation
KCCAKOOK_00472 3.5e-149 ykuT M mechanosensitive ion channel
KCCAKOOK_00473 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KCCAKOOK_00474 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KCCAKOOK_00475 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KCCAKOOK_00476 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
KCCAKOOK_00477 3.1e-80 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KCCAKOOK_00478 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
KCCAKOOK_00479 1.3e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KCCAKOOK_00480 2e-40 F nucleotide catabolic process
KCCAKOOK_00481 8.7e-98 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KCCAKOOK_00482 2.2e-41 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KCCAKOOK_00483 1.5e-187 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KCCAKOOK_00484 1.8e-83 nrdI F Belongs to the NrdI family
KCCAKOOK_00485 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCCAKOOK_00486 8.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KCCAKOOK_00487 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KCCAKOOK_00488 9e-206 ylbM S Belongs to the UPF0348 family
KCCAKOOK_00489 7.7e-140 yqeM Q Methyltransferase domain protein
KCCAKOOK_00490 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KCCAKOOK_00491 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KCCAKOOK_00492 4.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCCAKOOK_00493 3.5e-49 yhbY J RNA-binding protein
KCCAKOOK_00494 3.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KCCAKOOK_00495 5.1e-98 yqeG S hydrolase of the HAD superfamily
KCCAKOOK_00496 4.1e-151 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KCCAKOOK_00497 1.3e-57
KCCAKOOK_00498 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCCAKOOK_00499 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KCCAKOOK_00500 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCCAKOOK_00501 1.7e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KCCAKOOK_00502 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KCCAKOOK_00505 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCCAKOOK_00506 4.9e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCCAKOOK_00507 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCCAKOOK_00508 0.0 smc D Required for chromosome condensation and partitioning
KCCAKOOK_00509 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KCCAKOOK_00510 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCCAKOOK_00511 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCCAKOOK_00512 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KCCAKOOK_00513 1.1e-29 yyzM S Protein conserved in bacteria
KCCAKOOK_00514 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KCCAKOOK_00515 4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KCCAKOOK_00516 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCCAKOOK_00517 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KCCAKOOK_00518 2.7e-61 divIC D Septum formation initiator
KCCAKOOK_00520 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KCCAKOOK_00521 1.4e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KCCAKOOK_00522 1.7e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KCCAKOOK_00523 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCCAKOOK_00524 3e-30
KCCAKOOK_00525 9.5e-118 L Transposase
KCCAKOOK_00526 6.4e-37 yeeD O sulfur carrier activity
KCCAKOOK_00527 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KCCAKOOK_00528 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KCCAKOOK_00529 4.2e-62 manO S protein conserved in bacteria
KCCAKOOK_00530 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
KCCAKOOK_00531 1.7e-116 manM G pts system
KCCAKOOK_00532 1.3e-174 manL 2.7.1.191 G pts system
KCCAKOOK_00533 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KCCAKOOK_00534 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KCCAKOOK_00535 1.2e-247 pbuO S permease
KCCAKOOK_00536 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KCCAKOOK_00537 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
KCCAKOOK_00538 2.5e-220 brpA K Transcriptional
KCCAKOOK_00539 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KCCAKOOK_00540 3.1e-212 nusA K Participates in both transcription termination and antitermination
KCCAKOOK_00541 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KCCAKOOK_00542 1.4e-41 ylxQ J ribosomal protein
KCCAKOOK_00543 1.8e-74 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KCCAKOOK_00544 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCCAKOOK_00545 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KCCAKOOK_00546 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KCCAKOOK_00547 9.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCCAKOOK_00548 3.3e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCCAKOOK_00549 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KCCAKOOK_00551 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCCAKOOK_00552 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KCCAKOOK_00553 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
KCCAKOOK_00554 4.1e-291 scrB 3.2.1.26 GH32 G invertase
KCCAKOOK_00555 1.7e-179 scrR K Transcriptional
KCCAKOOK_00556 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCCAKOOK_00557 3.4e-62 yqhY S protein conserved in bacteria
KCCAKOOK_00558 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCCAKOOK_00559 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
KCCAKOOK_00560 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KCCAKOOK_00562 8e-44 V 'abc transporter, ATP-binding protein
KCCAKOOK_00563 1e-58 V 'abc transporter, ATP-binding protein
KCCAKOOK_00566 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCCAKOOK_00567 3.9e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
KCCAKOOK_00568 1.8e-85 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KCCAKOOK_00569 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCCAKOOK_00570 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCCAKOOK_00571 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KCCAKOOK_00572 8.9e-190 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KCCAKOOK_00573 1.1e-15 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KCCAKOOK_00574 5.3e-251 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KCCAKOOK_00575 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
KCCAKOOK_00576 6.3e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KCCAKOOK_00577 1.2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KCCAKOOK_00578 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KCCAKOOK_00579 3.1e-81 ypmB S Protein conserved in bacteria
KCCAKOOK_00580 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KCCAKOOK_00581 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KCCAKOOK_00582 1.5e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KCCAKOOK_00583 1.5e-192 desK 2.7.13.3 T Histidine kinase
KCCAKOOK_00584 1.4e-133 yvfS V ABC-2 type transporter
KCCAKOOK_00585 5.7e-158 XK27_09825 V abc transporter atp-binding protein
KCCAKOOK_00589 3.3e-212 EGP Major facilitator Superfamily
KCCAKOOK_00590 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
KCCAKOOK_00591 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
KCCAKOOK_00592 4.6e-42 3.6.1.55 F NUDIX domain
KCCAKOOK_00594 3.7e-122 S An automated process has identified a potential problem with this gene model
KCCAKOOK_00595 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
KCCAKOOK_00596 1.4e-15 liaI KT membrane
KCCAKOOK_00597 2.6e-30 liaI KT membrane
KCCAKOOK_00598 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
KCCAKOOK_00600 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
KCCAKOOK_00601 3.1e-10 L thioesterase
KCCAKOOK_00602 2.3e-142 S Macro domain protein
KCCAKOOK_00603 4.8e-51 trxA O Belongs to the thioredoxin family
KCCAKOOK_00604 7.2e-74 yccU S CoA-binding protein
KCCAKOOK_00605 4.1e-144 tatD L Hydrolase, tatd
KCCAKOOK_00606 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KCCAKOOK_00607 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KCCAKOOK_00609 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KCCAKOOK_00610 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KCCAKOOK_00611 5.4e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
KCCAKOOK_00612 6.9e-173 rmuC S RmuC domain protein
KCCAKOOK_00613 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
KCCAKOOK_00614 1.1e-142 purR 2.4.2.7 F operon repressor
KCCAKOOK_00615 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KCCAKOOK_00616 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KCCAKOOK_00617 1.2e-22 S Protein of unknown function (DUF3114)
KCCAKOOK_00618 9.8e-163 S Protein of unknown function (DUF3114)
KCCAKOOK_00619 9e-170 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KCCAKOOK_00620 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCCAKOOK_00622 4.4e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KCCAKOOK_00623 2e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KCCAKOOK_00624 1.1e-11 U protein secretion
KCCAKOOK_00625 2.1e-50 U protein secretion
KCCAKOOK_00626 3.5e-07 U protein secretion
KCCAKOOK_00628 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCCAKOOK_00629 2.5e-21
KCCAKOOK_00630 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KCCAKOOK_00631 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCCAKOOK_00632 7.4e-49 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KCCAKOOK_00633 4.6e-25 tatA U protein secretion
KCCAKOOK_00634 3.8e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCCAKOOK_00635 1.1e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KCCAKOOK_00636 5.6e-233 ycdB P peroxidase
KCCAKOOK_00637 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
KCCAKOOK_00638 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCCAKOOK_00639 9e-81 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCCAKOOK_00640 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCCAKOOK_00641 1.8e-210 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCCAKOOK_00642 2.5e-26 3.5.1.28 M GBS Bsp-like repeat
KCCAKOOK_00643 3.9e-263 3.5.1.28 NU amidase activity
KCCAKOOK_00644 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCCAKOOK_00645 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCCAKOOK_00646 7.7e-302 lpdA 1.8.1.4 C Dehydrogenase
KCCAKOOK_00647 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KCCAKOOK_00648 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCCAKOOK_00649 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KCCAKOOK_00650 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCCAKOOK_00651 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KCCAKOOK_00652 7e-144 recO L Involved in DNA repair and RecF pathway recombination
KCCAKOOK_00653 2.9e-218 araT 2.6.1.1 E Aminotransferase
KCCAKOOK_00654 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCCAKOOK_00655 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCCAKOOK_00656 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCCAKOOK_00657 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCCAKOOK_00658 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KCCAKOOK_00659 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCCAKOOK_00660 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KCCAKOOK_00661 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KCCAKOOK_00662 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KCCAKOOK_00663 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KCCAKOOK_00664 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KCCAKOOK_00665 2.6e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCCAKOOK_00666 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KCCAKOOK_00667 7.4e-104 rplD J Forms part of the polypeptide exit tunnel
KCCAKOOK_00668 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KCCAKOOK_00669 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KCCAKOOK_00670 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KCCAKOOK_00671 0.0 XK27_09800 I Acyltransferase
KCCAKOOK_00672 1.7e-35 XK27_09805 S MORN repeat protein
KCCAKOOK_00673 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCCAKOOK_00674 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCCAKOOK_00675 2.2e-19 S Bacterial lipoprotein
KCCAKOOK_00676 1.2e-10
KCCAKOOK_00677 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KCCAKOOK_00678 7e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCCAKOOK_00680 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KCCAKOOK_00681 1e-162 yxeN P ABC transporter (Permease
KCCAKOOK_00682 3.8e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
KCCAKOOK_00683 3.2e-09 S Protein of unknown function (DUF4059)
KCCAKOOK_00684 9.4e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KCCAKOOK_00685 1.1e-92 rsmD 2.1.1.171 L Methyltransferase
KCCAKOOK_00686 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCCAKOOK_00687 2.2e-196 ylbL T Belongs to the peptidase S16 family
KCCAKOOK_00688 4.9e-81 yhcC S radical SAM protein
KCCAKOOK_00689 3.7e-100 papP P ABC transporter (Permease
KCCAKOOK_00690 2.1e-113 V ABC transporter (Permease
KCCAKOOK_00691 4.5e-113 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KCCAKOOK_00692 1.6e-10
KCCAKOOK_00693 9e-98 K Transcriptional regulator, TetR family
KCCAKOOK_00694 1.8e-159 czcD P cation diffusion facilitator family transporter
KCCAKOOK_00695 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KCCAKOOK_00696 1.4e-195 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KCCAKOOK_00697 6e-08 S Hydrolases of the alpha beta superfamily
KCCAKOOK_00698 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
KCCAKOOK_00699 1e-78 S Alpha/beta hydrolase of unknown function (DUF915)
KCCAKOOK_00702 2.6e-143 2.4.2.3 F Phosphorylase superfamily
KCCAKOOK_00703 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KCCAKOOK_00704 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
KCCAKOOK_00705 1.2e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
KCCAKOOK_00706 3.1e-134 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCCAKOOK_00707 3.8e-60 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCCAKOOK_00708 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
KCCAKOOK_00709 2.2e-48 MA20_36090 S Protein of unknown function (DUF2974)
KCCAKOOK_00710 2.4e-128 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KCCAKOOK_00711 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KCCAKOOK_00712 1.5e-71 S Protein of unknown function (DUF1524)
KCCAKOOK_00713 1.6e-75 3.1.21.3 V Type I restriction modification DNA specificity domain protein
KCCAKOOK_00714 1.3e-42 S Phage derived protein Gp49-like (DUF891)
KCCAKOOK_00715 1e-42 K Helix-turn-helix domain
KCCAKOOK_00716 7.3e-305 hsdM 2.1.1.72 V type I restriction-modification system
KCCAKOOK_00717 5.9e-22 S PD-(D/E)XK nuclease family transposase
KCCAKOOK_00721 9.5e-140 blpT
KCCAKOOK_00722 3e-47 spiA K sequence-specific DNA binding
KCCAKOOK_00725 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KCCAKOOK_00726 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KCCAKOOK_00727 8.6e-44 V CAAX protease self-immunity
KCCAKOOK_00728 4.6e-140 cppA E CppA N-terminal
KCCAKOOK_00729 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KCCAKOOK_00730 6.2e-32
KCCAKOOK_00731 1.6e-117 ybbL S ATPases associated with a variety of cellular activities
KCCAKOOK_00732 1.5e-127 ybbM S transport system, permease component
KCCAKOOK_00733 3e-122 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
KCCAKOOK_00734 4.8e-58 L Phage integrase family
KCCAKOOK_00735 2.3e-31 L DNA integration
KCCAKOOK_00737 2e-177 yegQ O Peptidase U32
KCCAKOOK_00738 3.4e-252 yegQ O Peptidase U32
KCCAKOOK_00739 1.3e-85 bioY S biotin synthase
KCCAKOOK_00741 1.1e-33 XK27_12190 S protein conserved in bacteria
KCCAKOOK_00742 5.1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
KCCAKOOK_00743 9.6e-12
KCCAKOOK_00744 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
KCCAKOOK_00745 0.0 L helicase
KCCAKOOK_00746 8.7e-30 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KCCAKOOK_00747 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCCAKOOK_00748 3.8e-76 ilvN 2.2.1.6 E Acetolactate synthase
KCCAKOOK_00749 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KCCAKOOK_00750 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KCCAKOOK_00751 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KCCAKOOK_00752 2.9e-304 yloV S kinase related to dihydroxyacetone kinase
KCCAKOOK_00753 5.2e-57 asp S cog cog1302
KCCAKOOK_00754 9.3e-226 norN V Mate efflux family protein
KCCAKOOK_00755 1.9e-278 thrC 4.2.3.1 E Threonine synthase
KCCAKOOK_00756 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
KCCAKOOK_00757 3.5e-79 hsdM 2.1.1.72 V type I restriction-modification system
KCCAKOOK_00758 3.5e-155 glcU U Glucose uptake
KCCAKOOK_00759 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
KCCAKOOK_00760 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
KCCAKOOK_00761 1.1e-111 XK27_10720 D peptidase activity
KCCAKOOK_00762 2.1e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
KCCAKOOK_00763 2.2e-08
KCCAKOOK_00764 1.2e-172 yeiH S Membrane
KCCAKOOK_00765 3.3e-116 mur1 3.4.17.14, 3.5.1.28 NU muramidase
KCCAKOOK_00766 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCCAKOOK_00767 3.8e-40 K transcriptional
KCCAKOOK_00769 2.6e-76 S thiolester hydrolase activity
KCCAKOOK_00770 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
KCCAKOOK_00771 3.7e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCCAKOOK_00772 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KCCAKOOK_00773 1.9e-77 yhaI L Membrane
KCCAKOOK_00774 5.1e-259 pepC 3.4.22.40 E aminopeptidase
KCCAKOOK_00777 2.4e-75 XK27_03180 T universal stress protein
KCCAKOOK_00778 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KCCAKOOK_00779 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KCCAKOOK_00780 6.8e-101 pncA Q isochorismatase
KCCAKOOK_00781 9.8e-23 hlpA M Belongs to the NlpA lipoprotein family
KCCAKOOK_00782 7.8e-94 hlpA M Belongs to the NlpA lipoprotein family
KCCAKOOK_00783 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCCAKOOK_00784 8e-96 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCCAKOOK_00785 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCCAKOOK_00786 6.1e-29 M lipopolysaccharide 3-alpha-galactosyltransferase activity
KCCAKOOK_00787 1e-13 isaA GH23 M Immunodominant staphylococcal antigen A
KCCAKOOK_00788 5.3e-85 lytE M LysM domain protein
KCCAKOOK_00789 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCCAKOOK_00790 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCCAKOOK_00791 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCCAKOOK_00792 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCCAKOOK_00793 6.3e-138 ymfM S sequence-specific DNA binding
KCCAKOOK_00794 3.1e-242 ymfH S Peptidase M16
KCCAKOOK_00795 4.8e-235 ymfF S Peptidase M16
KCCAKOOK_00796 1.6e-45 yaaA S S4 domain protein YaaA
KCCAKOOK_00797 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCCAKOOK_00798 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KCCAKOOK_00799 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KCCAKOOK_00800 1.1e-153 yvjA S membrane
KCCAKOOK_00801 6.7e-306 ybiT S abc transporter atp-binding protein
KCCAKOOK_00802 0.0 XK27_10405 S Bacterial membrane protein YfhO
KCCAKOOK_00803 5e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KCCAKOOK_00804 1.6e-205 S Protein of unknown function (DUF917)
KCCAKOOK_00805 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
KCCAKOOK_00806 3.9e-111 proWZ P ABC transporter (Permease
KCCAKOOK_00807 2e-169 proX M ABC transporter, substrate-binding protein, QAT family
KCCAKOOK_00808 1.5e-138 proV E abc transporter atp-binding protein
KCCAKOOK_00809 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
KCCAKOOK_00810 1.8e-13 bioY S biotin synthase
KCCAKOOK_00811 7.9e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KCCAKOOK_00812 3.6e-100 acmA 3.2.1.17 NU amidase activity
KCCAKOOK_00813 5.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KCCAKOOK_00814 1.1e-70 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCCAKOOK_00815 9.8e-298 dnaK O Heat shock 70 kDa protein
KCCAKOOK_00816 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KCCAKOOK_00817 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KCCAKOOK_00818 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KCCAKOOK_00819 5e-60 hmpT S membrane
KCCAKOOK_00820 1.2e-138 1.13.11.2 S glyoxalase
KCCAKOOK_00821 5.6e-77 ywnA K Transcriptional regulator
KCCAKOOK_00822 4e-156 E Alpha/beta hydrolase of unknown function (DUF915)
KCCAKOOK_00823 4.3e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KCCAKOOK_00824 1.4e-110 drgA C Nitroreductase
KCCAKOOK_00825 1.9e-101 yoaK S Protein of unknown function (DUF1275)
KCCAKOOK_00826 6.8e-161 yvgN C reductase
KCCAKOOK_00827 4.6e-143 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCCAKOOK_00828 6.8e-150 L Integrase core domain protein
KCCAKOOK_00829 1.8e-87 L transposase activity
KCCAKOOK_00831 2.8e-85
KCCAKOOK_00832 0.0 sbcC L ATPase involved in DNA repair
KCCAKOOK_00833 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KCCAKOOK_00834 4.2e-73 XK27_09675 K -acetyltransferase
KCCAKOOK_00835 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KCCAKOOK_00836 2.5e-23
KCCAKOOK_00837 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KCCAKOOK_00838 2.1e-273 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KCCAKOOK_00839 2.5e-30 artQ P ABC transporter (Permease
KCCAKOOK_00840 7.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCCAKOOK_00841 1.8e-156 aatB ET ABC transporter substrate-binding protein
KCCAKOOK_00842 1.8e-72 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCCAKOOK_00843 2.6e-16 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCCAKOOK_00844 1.5e-66 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCCAKOOK_00845 2.1e-07
KCCAKOOK_00846 6.6e-62 adhP 1.1.1.1 C alcohol dehydrogenase
KCCAKOOK_00847 8.7e-111 adhP 1.1.1.1 C alcohol dehydrogenase
KCCAKOOK_00849 3e-21
KCCAKOOK_00850 0.0 res_1 3.1.21.5 S Type III restriction
KCCAKOOK_00851 2.5e-36 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KCCAKOOK_00852 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KCCAKOOK_00855 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KCCAKOOK_00856 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
KCCAKOOK_00857 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KCCAKOOK_00858 9e-121 ylfI S tigr01906
KCCAKOOK_00859 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KCCAKOOK_00860 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KCCAKOOK_00861 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KCCAKOOK_00862 5.7e-97 puuD T peptidase C26
KCCAKOOK_00863 6.2e-120 radC E Belongs to the UPF0758 family
KCCAKOOK_00864 0.0 rgpF M Rhamnan synthesis protein F
KCCAKOOK_00865 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KCCAKOOK_00866 2.5e-225 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KCCAKOOK_00867 1.4e-142 rgpC GM Transport permease protein
KCCAKOOK_00868 6.3e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
KCCAKOOK_00869 5e-133 rgpA GT4 M Domain of unknown function (DUF1972)
KCCAKOOK_00871 1.9e-07
KCCAKOOK_00876 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCCAKOOK_00877 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KCCAKOOK_00878 5.5e-36 XK27_02060 S Transglycosylase associated protein
KCCAKOOK_00879 2.6e-55 badR K DNA-binding transcription factor activity
KCCAKOOK_00880 3.5e-97 S reductase
KCCAKOOK_00883 4.7e-43
KCCAKOOK_00884 6.8e-56 S TM2 domain
KCCAKOOK_00885 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCCAKOOK_00886 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCCAKOOK_00887 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
KCCAKOOK_00888 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KCCAKOOK_00889 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KCCAKOOK_00890 4e-47 cof Q phosphatase activity
KCCAKOOK_00891 1.1e-34 cof Q phosphatase activity
KCCAKOOK_00892 4e-64 clcA_2 P chloride
KCCAKOOK_00893 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
KCCAKOOK_00894 7e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
KCCAKOOK_00895 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KCCAKOOK_00896 2.7e-253 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KCCAKOOK_00897 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KCCAKOOK_00898 1.4e-106 cps4C M biosynthesis protein
KCCAKOOK_00899 5.5e-114 cpsD D COG0489 ATPases involved in chromosome partitioning
KCCAKOOK_00900 5.8e-07 ytxH S General stress protein
KCCAKOOK_00902 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCCAKOOK_00903 2.3e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KCCAKOOK_00904 9.9e-42 pspC KT PspC domain
KCCAKOOK_00905 0.0 yhgF K Transcriptional accessory protein
KCCAKOOK_00907 3.5e-155 XK27_03015 S permease
KCCAKOOK_00908 4.3e-32 yhcC S radical SAM protein
KCCAKOOK_00909 2.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
KCCAKOOK_00911 0.0 yjcE P NhaP-type Na H and K H antiporters
KCCAKOOK_00912 1.2e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KCCAKOOK_00913 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KCCAKOOK_00914 4.5e-58 XK27_04120 S Putative amino acid metabolism
KCCAKOOK_00915 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
KCCAKOOK_00916 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCCAKOOK_00917 1.5e-103 yjbK S Adenylate cyclase
KCCAKOOK_00918 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KCCAKOOK_00919 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KCCAKOOK_00920 1.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KCCAKOOK_00921 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KCCAKOOK_00922 2.4e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KCCAKOOK_00923 5e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCCAKOOK_00925 1.1e-08 V Glucan-binding protein C
KCCAKOOK_00926 6.1e-22 V Glucan-binding protein C
KCCAKOOK_00927 1.2e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
KCCAKOOK_00928 2.4e-275 pepV 3.5.1.18 E Dipeptidase
KCCAKOOK_00929 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KCCAKOOK_00930 2e-85 XK27_03610 K Gnat family
KCCAKOOK_00931 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KCCAKOOK_00932 4.3e-40 V abc transporter atp-binding protein
KCCAKOOK_00933 1.7e-20 V abc transporter atp-binding protein
KCCAKOOK_00934 7.3e-59 V abc transporter atp-binding protein
KCCAKOOK_00935 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KCCAKOOK_00936 1.2e-32 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KCCAKOOK_00937 7.5e-109 M translation initiation factor activity
KCCAKOOK_00938 3.3e-74 M translation initiation factor activity
KCCAKOOK_00939 1.2e-25 L transposition
KCCAKOOK_00940 2.7e-08 L Integrase core domain protein
KCCAKOOK_00941 2.1e-210 spaC2 V Lanthionine synthetase C family protein
KCCAKOOK_00942 8.6e-184 EGP Major facilitator Superfamily
KCCAKOOK_00943 5.9e-24 3.6.4.12
KCCAKOOK_00944 5.9e-91 3.6.4.12 K Divergent AAA domain protein
KCCAKOOK_00945 2.2e-224 int L Belongs to the 'phage' integrase family
KCCAKOOK_00946 1.8e-38 S Helix-turn-helix domain
KCCAKOOK_00947 3.9e-177
KCCAKOOK_00949 3.4e-75 isp2 S pathogenesis
KCCAKOOK_00950 9.3e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KCCAKOOK_00951 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCCAKOOK_00952 4.2e-294 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KCCAKOOK_00953 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KCCAKOOK_00954 2.3e-184 galR K Transcriptional regulator
KCCAKOOK_00955 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCCAKOOK_00957 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KCCAKOOK_00958 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KCCAKOOK_00959 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
KCCAKOOK_00960 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCCAKOOK_00961 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KCCAKOOK_00962 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KCCAKOOK_00965 2e-157 rrmA 2.1.1.187 Q methyltransferase
KCCAKOOK_00966 1.5e-64 S phosphatase activity
KCCAKOOK_00967 1.6e-21 S glycolate biosynthetic process
KCCAKOOK_00968 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KCCAKOOK_00969 1.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KCCAKOOK_00970 5e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCCAKOOK_00971 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KCCAKOOK_00973 8e-277 S Protein of unknown function (DUF3114)
KCCAKOOK_00974 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
KCCAKOOK_00975 7.7e-198 V (ABC) transporter
KCCAKOOK_00976 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
KCCAKOOK_00977 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
KCCAKOOK_00978 1.1e-113 K sequence-specific DNA binding
KCCAKOOK_00979 4.9e-39 S granule-associated protein
KCCAKOOK_00980 2e-294 S unusual protein kinase
KCCAKOOK_00981 4.8e-21 estA E Lysophospholipase L1 and related esterases
KCCAKOOK_00982 3.9e-78 estA E GDSL-like protein
KCCAKOOK_00983 4.9e-159 rssA S Phospholipase, patatin family
KCCAKOOK_00984 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCCAKOOK_00985 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCCAKOOK_00986 3.8e-205 EGP Transmembrane secretion effector
KCCAKOOK_00987 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
KCCAKOOK_00988 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCCAKOOK_00989 1e-42 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCCAKOOK_00990 2.7e-88 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCCAKOOK_00991 1.9e-201 yjbB G Permeases of the major facilitator superfamily
KCCAKOOK_00992 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KCCAKOOK_00993 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
KCCAKOOK_00994 5.7e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KCCAKOOK_00997 3.3e-95 ywlG S Belongs to the UPF0340 family
KCCAKOOK_00998 1.2e-85 treR K trehalose operon
KCCAKOOK_00999 5.8e-21 treR K DNA-binding transcription factor activity
KCCAKOOK_01000 1.4e-54 treB 2.7.1.201 G PTS System
KCCAKOOK_01001 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCCAKOOK_01002 1.5e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCCAKOOK_01003 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCCAKOOK_01004 0.0 pepO 3.4.24.71 O Peptidase family M13
KCCAKOOK_01005 2.8e-146 pyrP F uracil Permease
KCCAKOOK_01006 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KCCAKOOK_01007 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KCCAKOOK_01008 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KCCAKOOK_01009 0.0 M family 8
KCCAKOOK_01010 2.7e-09
KCCAKOOK_01011 9.6e-08
KCCAKOOK_01012 5.8e-109 MA20_06410 E LysE type translocator
KCCAKOOK_01013 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
KCCAKOOK_01014 4.4e-61 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCCAKOOK_01016 5.5e-258 I radical SAM domain protein
KCCAKOOK_01017 1.2e-176 EGP Major Facilitator Superfamily
KCCAKOOK_01018 3.9e-110 C Fe-S oxidoreductases
KCCAKOOK_01020 1.1e-151 V MatE
KCCAKOOK_01021 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
KCCAKOOK_01022 1.6e-63 XK27_02560 S cog cog2151
KCCAKOOK_01023 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KCCAKOOK_01024 7.7e-227 ytfP S Flavoprotein
KCCAKOOK_01026 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KCCAKOOK_01027 7.6e-114 ytmP 2.7.1.89 M Phosphotransferase
KCCAKOOK_01028 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KCCAKOOK_01029 7.9e-86 pbuX F xanthine permease
KCCAKOOK_01030 2.3e-114 pbuX F xanthine permease
KCCAKOOK_01031 2.9e-246 norM V Multidrug efflux pump
KCCAKOOK_01032 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCCAKOOK_01033 7.8e-236 brnQ E Component of the transport system for branched-chain amino acids
KCCAKOOK_01034 9.5e-141 lmrA2 V abc transporter atp-binding protein
KCCAKOOK_01035 2.2e-18 K Acetyltransferase (GNAT) family
KCCAKOOK_01036 2.9e-120 sptS 2.7.13.3 T Histidine kinase
KCCAKOOK_01037 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KCCAKOOK_01038 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KCCAKOOK_01039 5.3e-161 cvfB S Protein conserved in bacteria
KCCAKOOK_01040 7.4e-35 yozE S Belongs to the UPF0346 family
KCCAKOOK_01041 3.2e-93 V VanZ like family
KCCAKOOK_01042 1.1e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KCCAKOOK_01043 2.1e-67 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
KCCAKOOK_01044 2.5e-95 pgm G Belongs to the phosphoglycerate mutase family
KCCAKOOK_01045 7.2e-104 G Belongs to the phosphoglycerate mutase family
KCCAKOOK_01046 6.6e-102 G Belongs to the phosphoglycerate mutase family
KCCAKOOK_01047 1.3e-199 S hmm pf01594
KCCAKOOK_01048 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCCAKOOK_01049 6.4e-96 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCCAKOOK_01050 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
KCCAKOOK_01051 4e-84 L Transposase
KCCAKOOK_01052 2.1e-113 fruR K transcriptional
KCCAKOOK_01053 6e-163 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KCCAKOOK_01054 2.1e-78 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
KCCAKOOK_01055 1.8e-73 S Psort location CytoplasmicMembrane, score
KCCAKOOK_01056 6.2e-56 S Domain of unknown function (DUF4430)
KCCAKOOK_01057 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KCCAKOOK_01058 7.1e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
KCCAKOOK_01059 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KCCAKOOK_01060 2.6e-220 amrA S polysaccharide biosynthetic process
KCCAKOOK_01061 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
KCCAKOOK_01062 7.6e-126 ycbB S Glycosyl transferase family 2
KCCAKOOK_01063 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KCCAKOOK_01064 1.1e-245
KCCAKOOK_01065 3.6e-76 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KCCAKOOK_01066 7.4e-253 cycA E permease
KCCAKOOK_01067 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
KCCAKOOK_01068 1.5e-25 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KCCAKOOK_01069 5.8e-71 pts33BCA G pts system
KCCAKOOK_01070 9e-96 pts33BCA G pts system
KCCAKOOK_01071 2e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
KCCAKOOK_01072 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCCAKOOK_01073 5.4e-141 1.1.1.169 H Ketopantoate reductase
KCCAKOOK_01074 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KCCAKOOK_01075 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KCCAKOOK_01076 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
KCCAKOOK_01077 6.8e-161 S CHAP domain
KCCAKOOK_01078 3.8e-31 L Integrase core domain protein
KCCAKOOK_01079 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCCAKOOK_01080 1.8e-164 K transcriptional regulator (lysR family)
KCCAKOOK_01081 1.4e-186 coiA 3.6.4.12 S Competence protein
KCCAKOOK_01082 0.0 pepF E oligoendopeptidase F
KCCAKOOK_01083 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
KCCAKOOK_01084 5.1e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KCCAKOOK_01085 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KCCAKOOK_01086 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCCAKOOK_01087 1.3e-147 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCCAKOOK_01088 2.3e-103 3.4.17.14, 3.5.1.28 NU amidase activity
KCCAKOOK_01089 6.9e-147 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KCCAKOOK_01090 8.5e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KCCAKOOK_01091 1.7e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCCAKOOK_01092 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KCCAKOOK_01093 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KCCAKOOK_01094 1.1e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KCCAKOOK_01095 4.1e-132 yxkH G deacetylase
KCCAKOOK_01096 8.9e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KCCAKOOK_01097 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KCCAKOOK_01098 9.4e-153 rarD S Transporter
KCCAKOOK_01099 2.4e-14 T peptidase
KCCAKOOK_01100 8.9e-14 coiA 3.6.4.12 S Competence protein
KCCAKOOK_01101 3e-107 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KCCAKOOK_01102 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KCCAKOOK_01103 1.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCCAKOOK_01104 1.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
KCCAKOOK_01105 2.3e-76 atpF C ATP synthase F(0) sector subunit b
KCCAKOOK_01106 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCCAKOOK_01107 2.5e-278 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCCAKOOK_01108 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KCCAKOOK_01109 6.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KCCAKOOK_01110 2e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KCCAKOOK_01111 7.5e-228 ftsW D Belongs to the SEDS family
KCCAKOOK_01112 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCCAKOOK_01113 3.4e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KCCAKOOK_01114 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCCAKOOK_01115 3.2e-161 holB 2.7.7.7 L dna polymerase iii
KCCAKOOK_01116 3.1e-134 yaaT S stage 0 sporulation protein
KCCAKOOK_01117 9.5e-55 yabA L Involved in initiation control of chromosome replication
KCCAKOOK_01118 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KCCAKOOK_01119 2.9e-232 amt P Ammonium Transporter
KCCAKOOK_01120 1.1e-53 glnB K Belongs to the P(II) protein family
KCCAKOOK_01121 4.9e-106 mur1 NU mannosyl-glycoprotein
KCCAKOOK_01122 5e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KCCAKOOK_01123 6.8e-115 nptA P COG1283 Na phosphate symporter
KCCAKOOK_01124 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCCAKOOK_01125 4.9e-51
KCCAKOOK_01126 2.2e-25
KCCAKOOK_01127 3.9e-60
KCCAKOOK_01128 6.1e-63 S membrane
KCCAKOOK_01129 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KCCAKOOK_01130 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KCCAKOOK_01131 4.5e-39 ynzC S UPF0291 protein
KCCAKOOK_01132 4.8e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KCCAKOOK_01133 8.5e-134 parB K Belongs to the ParB family
KCCAKOOK_01134 5.8e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KCCAKOOK_01135 1.2e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCCAKOOK_01136 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
KCCAKOOK_01140 1.4e-62 yecS P ABC transporter (Permease
KCCAKOOK_01141 2.3e-20 yecS P amino acid transport
KCCAKOOK_01143 2e-272 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KCCAKOOK_01144 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
KCCAKOOK_01145 1.4e-104 yfiF3 K sequence-specific DNA binding
KCCAKOOK_01146 2e-160 S hydrolase
KCCAKOOK_01147 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
KCCAKOOK_01148 5.1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCCAKOOK_01149 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
KCCAKOOK_01150 2.7e-27 P Hemerythrin HHE cation binding domain protein
KCCAKOOK_01151 1e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCCAKOOK_01152 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
KCCAKOOK_01153 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KCCAKOOK_01154 2.7e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KCCAKOOK_01155 4.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KCCAKOOK_01156 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCCAKOOK_01159 7e-251 M Psort location CytoplasmicMembrane, score
KCCAKOOK_01160 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KCCAKOOK_01161 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KCCAKOOK_01162 1.7e-290 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KCCAKOOK_01163 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KCCAKOOK_01164 1.9e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCCAKOOK_01165 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KCCAKOOK_01166 1.4e-167 fhuR K transcriptional regulator (lysR family)
KCCAKOOK_01170 1.2e-34
KCCAKOOK_01172 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KCCAKOOK_01173 4.4e-166 dnaI L Primosomal protein DnaI
KCCAKOOK_01174 5.5e-217 dnaB L Replication initiation and membrane attachment
KCCAKOOK_01175 3e-16 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCCAKOOK_01176 8.7e-162 whiA K May be required for sporulation
KCCAKOOK_01177 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KCCAKOOK_01178 1.2e-163 rapZ S Displays ATPase and GTPase activities
KCCAKOOK_01179 7e-136 yejC S cyclic nucleotide-binding protein
KCCAKOOK_01180 7.3e-20 D nuclear chromosome segregation
KCCAKOOK_01181 5.4e-58 K LytTr DNA-binding domain
KCCAKOOK_01182 7e-34 S Protein of unknown function (DUF3021)
KCCAKOOK_01183 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCCAKOOK_01184 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KCCAKOOK_01185 8.2e-70 argR K Regulates arginine biosynthesis genes
KCCAKOOK_01186 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KCCAKOOK_01187 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCCAKOOK_01188 1.3e-15 1.13.11.2 S glyoxalase
KCCAKOOK_01189 2.2e-108 XK27_02070 S nitroreductase
KCCAKOOK_01190 4.3e-245 yfnA E amino acid
KCCAKOOK_01191 9.6e-26 csbD K CsbD-like
KCCAKOOK_01192 6.3e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCCAKOOK_01193 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCCAKOOK_01194 1.5e-25 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KCCAKOOK_01195 8e-165 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KCCAKOOK_01196 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KCCAKOOK_01197 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCCAKOOK_01198 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KCCAKOOK_01199 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KCCAKOOK_01200 2e-33 secG U Preprotein translocase subunit SecG
KCCAKOOK_01201 9.5e-74 mdtG EGP Major facilitator Superfamily
KCCAKOOK_01202 6e-133 mdtG EGP Major facilitator Superfamily
KCCAKOOK_01203 6.4e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KCCAKOOK_01204 9.3e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KCCAKOOK_01205 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCCAKOOK_01206 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KCCAKOOK_01207 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KCCAKOOK_01208 6.8e-53 licT K transcriptional antiterminator
KCCAKOOK_01209 1.3e-63 licT K transcriptional antiterminator
KCCAKOOK_01210 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KCCAKOOK_01211 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KCCAKOOK_01212 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KCCAKOOK_01213 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCCAKOOK_01214 7.5e-23 I Alpha/beta hydrolase family
KCCAKOOK_01215 2.5e-33 yugF I carboxylic ester hydrolase activity
KCCAKOOK_01216 2.2e-45 K sequence-specific DNA binding
KCCAKOOK_01217 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KCCAKOOK_01218 1.5e-07
KCCAKOOK_01219 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KCCAKOOK_01220 1.1e-78 feoA P FeoA domain protein
KCCAKOOK_01221 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCCAKOOK_01222 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KCCAKOOK_01223 1.3e-34 ykuJ S protein conserved in bacteria
KCCAKOOK_01224 2.4e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCCAKOOK_01225 0.0 clpE O Belongs to the ClpA ClpB family
KCCAKOOK_01226 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KCCAKOOK_01227 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
KCCAKOOK_01228 1.2e-65 S oxidoreductase
KCCAKOOK_01229 1.5e-50 S oxidoreductase
KCCAKOOK_01230 6.4e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
KCCAKOOK_01231 6.1e-70 M Pfam SNARE associated Golgi protein
KCCAKOOK_01232 3.9e-31 S Domain of Unknown Function with PDB structure (DUF3862)
KCCAKOOK_01233 1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
KCCAKOOK_01236 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
KCCAKOOK_01239 4.8e-16 S Protein of unknown function (DUF2969)
KCCAKOOK_01240 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
KCCAKOOK_01241 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCCAKOOK_01242 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCCAKOOK_01243 1.2e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KCCAKOOK_01244 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
KCCAKOOK_01245 1.4e-29 S Domain of unknown function (DUF1912)
KCCAKOOK_01246 3.4e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KCCAKOOK_01247 8.3e-249 mmuP E amino acid
KCCAKOOK_01248 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KCCAKOOK_01249 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCCAKOOK_01250 9.7e-22
KCCAKOOK_01251 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCCAKOOK_01252 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KCCAKOOK_01253 1.7e-218 mvaS 2.3.3.10 I synthase
KCCAKOOK_01254 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
KCCAKOOK_01255 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
KCCAKOOK_01256 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KCCAKOOK_01257 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KCCAKOOK_01258 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KCCAKOOK_01259 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KCCAKOOK_01260 4.1e-27 ytrF V efflux transmembrane transporter activity
KCCAKOOK_01261 3.1e-31 V efflux transmembrane transporter activity
KCCAKOOK_01262 3.6e-35 V efflux transmembrane transporter activity
KCCAKOOK_01263 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
KCCAKOOK_01264 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
KCCAKOOK_01265 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KCCAKOOK_01266 2.6e-166 cpsY K Transcriptional regulator
KCCAKOOK_01267 1.9e-83 L transposition
KCCAKOOK_01268 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KCCAKOOK_01269 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KCCAKOOK_01270 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KCCAKOOK_01271 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KCCAKOOK_01272 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KCCAKOOK_01273 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCCAKOOK_01274 3.3e-62 rplQ J ribosomal protein l17
KCCAKOOK_01275 2.8e-51 L PFAM Integrase, catalytic core
KCCAKOOK_01276 7.8e-40 L Transposase
KCCAKOOK_01277 3.4e-154 L Integrase core domain protein
KCCAKOOK_01280 9.8e-71 L Phage integrase family
KCCAKOOK_01281 2.4e-23 S phage tail tape measure protein
KCCAKOOK_01282 7.1e-130 S EcsC protein family
KCCAKOOK_01283 4.4e-20 S phage tail
KCCAKOOK_01284 9.6e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KCCAKOOK_01285 4.4e-58 rplO J binds to the 23S rRNA
KCCAKOOK_01286 2.5e-23 rpmD J ribosomal protein l30
KCCAKOOK_01287 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KCCAKOOK_01288 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KCCAKOOK_01289 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KCCAKOOK_01290 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KCCAKOOK_01291 7.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
KCCAKOOK_01292 1.5e-303 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KCCAKOOK_01293 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCCAKOOK_01294 2.6e-109 3.1.3.18 S IA, variant 1
KCCAKOOK_01295 2.2e-117 lrgB M effector of murein hydrolase
KCCAKOOK_01296 7.7e-56 lrgA S Effector of murein hydrolase LrgA
KCCAKOOK_01298 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
KCCAKOOK_01299 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KCCAKOOK_01300 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCCAKOOK_01301 6.6e-104 wecD M Acetyltransferase (GNAT) domain
KCCAKOOK_01302 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KCCAKOOK_01303 5.6e-113 GK ROK family
KCCAKOOK_01304 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
KCCAKOOK_01305 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
KCCAKOOK_01306 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
KCCAKOOK_01307 2.3e-206 potD P spermidine putrescine ABC transporter
KCCAKOOK_01308 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
KCCAKOOK_01309 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
KCCAKOOK_01310 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KCCAKOOK_01311 7.8e-171 murB 1.3.1.98 M cell wall formation
KCCAKOOK_01312 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCCAKOOK_01313 7.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCCAKOOK_01314 5.1e-297 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KCCAKOOK_01315 2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCCAKOOK_01316 3.8e-99 folE 3.5.4.16 F gtp cyclohydrolase
KCCAKOOK_01317 0.0 ydaO E amino acid
KCCAKOOK_01318 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KCCAKOOK_01319 4.1e-37 ylqC L Belongs to the UPF0109 family
KCCAKOOK_01320 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KCCAKOOK_01321 4.5e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KCCAKOOK_01322 2.6e-157 xth 3.1.11.2 L exodeoxyribonuclease III
KCCAKOOK_01323 2.1e-74 S QueT transporter
KCCAKOOK_01324 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KCCAKOOK_01325 4e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KCCAKOOK_01326 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KCCAKOOK_01327 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCCAKOOK_01328 3.7e-85 ccl S cog cog4708
KCCAKOOK_01329 7.4e-164 rbn E Belongs to the UPF0761 family
KCCAKOOK_01330 5.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KCCAKOOK_01331 3.3e-231 ytoI K transcriptional regulator containing CBS domains
KCCAKOOK_01332 7e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KCCAKOOK_01333 3.1e-234 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCCAKOOK_01334 0.0 comEC S Competence protein ComEC
KCCAKOOK_01335 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KCCAKOOK_01336 1.3e-142 plsC 2.3.1.51 I Acyltransferase
KCCAKOOK_01337 3.5e-78 nodB3 G polysaccharide deacetylase
KCCAKOOK_01338 2.3e-47 nodB3 G polysaccharide deacetylase
KCCAKOOK_01339 2.3e-139 yabB 2.1.1.223 L Methyltransferase
KCCAKOOK_01340 3e-41 yazA L endonuclease containing a URI domain
KCCAKOOK_01342 3.3e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KCCAKOOK_01343 2.3e-154 corA P CorA-like protein
KCCAKOOK_01344 1.9e-62 yjqA S Bacterial PH domain
KCCAKOOK_01345 1.3e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KCCAKOOK_01346 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KCCAKOOK_01347 3.5e-140 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KCCAKOOK_01348 3.9e-290 hsdM 2.1.1.72 V N-6 DNA Methylase
KCCAKOOK_01349 2.2e-147 3.1.21.3 V type I restriction modification DNA specificity domain
KCCAKOOK_01351 3e-38
KCCAKOOK_01352 1.3e-296 ccs S the current gene model (or a revised gene model) may contain a frame shift
KCCAKOOK_01353 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KCCAKOOK_01354 7.5e-14
KCCAKOOK_01355 2.6e-91 XK27_10930 K acetyltransferase
KCCAKOOK_01356 3.1e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCCAKOOK_01357 1.8e-147 yaaA S Belongs to the UPF0246 family
KCCAKOOK_01358 2.7e-166 XK27_01785 S cog cog1284
KCCAKOOK_01359 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KCCAKOOK_01361 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
KCCAKOOK_01362 4e-53 metE 2.1.1.14 E Methionine synthase
KCCAKOOK_01363 5.2e-65 metE 2.1.1.14 E Methionine synthase
KCCAKOOK_01364 1.4e-36 metE 2.1.1.14 E Methionine synthase
KCCAKOOK_01365 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KCCAKOOK_01366 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KCCAKOOK_01367 1.7e-38 K Transcriptional regulator
KCCAKOOK_01369 1.7e-08 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCCAKOOK_01370 2.8e-65 Q Condensation domain
KCCAKOOK_01371 4.5e-77 Q Ketoacyl-synthetase C-terminal extension
KCCAKOOK_01372 4.1e-30 S Protein of unknown function with HXXEE motif
KCCAKOOK_01373 1.5e-89 V ABC transporter, ATP-binding protein
KCCAKOOK_01374 4.4e-263 V ABC transporter (Permease)
KCCAKOOK_01375 1.2e-21 L Type II restriction endonuclease, TdeIII
KCCAKOOK_01376 1.2e-11 K Transcriptional
KCCAKOOK_01377 8.9e-28 E IrrE N-terminal-like domain
KCCAKOOK_01380 2.2e-50 yegS 2.7.1.107 I Diacylglycerol kinase
KCCAKOOK_01381 1.4e-94 S Hydrophobic domain protein
KCCAKOOK_01383 3.7e-27 S Membrane
KCCAKOOK_01384 3.1e-101
KCCAKOOK_01385 1.8e-23 S Small integral membrane protein
KCCAKOOK_01386 1.1e-71 M Protein conserved in bacteria
KCCAKOOK_01387 4.9e-12 K CsbD-like
KCCAKOOK_01388 3.5e-97 nudL L hydrolase
KCCAKOOK_01389 3.4e-13 nudL L hydrolase
KCCAKOOK_01390 4e-19 K negative regulation of transcription, DNA-templated
KCCAKOOK_01391 1.7e-23 K negative regulation of transcription, DNA-templated
KCCAKOOK_01393 1.2e-18 XK27_06920 S Protein of unknown function (DUF1700)
KCCAKOOK_01394 1.8e-88 S Putative adhesin
KCCAKOOK_01395 3.9e-161 XK27_06930 V domain protein
KCCAKOOK_01396 6.4e-96 XK27_06935 K transcriptional regulator
KCCAKOOK_01397 4.8e-55 ypaA M Membrane
KCCAKOOK_01398 2.7e-08
KCCAKOOK_01399 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KCCAKOOK_01400 8.2e-48 veg S Biofilm formation stimulator VEG
KCCAKOOK_01401 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KCCAKOOK_01402 3.9e-70 rplI J binds to the 23S rRNA
KCCAKOOK_01403 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KCCAKOOK_01404 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KCCAKOOK_01405 1.5e-77 F NUDIX domain
KCCAKOOK_01406 3.3e-225 capA M Bacterial capsule synthesis protein
KCCAKOOK_01407 3.6e-39 gcvR T UPF0237 protein
KCCAKOOK_01408 4.3e-242 XK27_08635 S UPF0210 protein
KCCAKOOK_01409 0.0 lacL 3.2.1.23 G -beta-galactosidase
KCCAKOOK_01410 6.4e-100 lacS G transporter
KCCAKOOK_01411 9.1e-18 KT response to antibiotic
KCCAKOOK_01412 5.9e-54 yebC M Membrane
KCCAKOOK_01413 2.9e-18 yebC M Membrane
KCCAKOOK_01414 2.6e-258 XK27_03190 S hydrolases of the HAD superfamily
KCCAKOOK_01415 1.9e-59 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KCCAKOOK_01416 1.3e-105 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KCCAKOOK_01419 6.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KCCAKOOK_01420 1.8e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCCAKOOK_01421 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KCCAKOOK_01422 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCCAKOOK_01423 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KCCAKOOK_01424 5e-23 M LysM domain
KCCAKOOK_01425 1.4e-89 ebsA S Family of unknown function (DUF5322)
KCCAKOOK_01426 1.5e-97 ybhL S Belongs to the BI1 family
KCCAKOOK_01427 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KCCAKOOK_01428 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCCAKOOK_01429 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KCCAKOOK_01430 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCCAKOOK_01431 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KCCAKOOK_01432 1.6e-38 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KCCAKOOK_01433 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KCCAKOOK_01434 1.3e-93 ypsA S Belongs to the UPF0398 family
KCCAKOOK_01435 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KCCAKOOK_01436 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KCCAKOOK_01441 8e-191 phoH T phosphate starvation-inducible protein PhoH
KCCAKOOK_01442 2.3e-61 rlpA M LysM domain protein
KCCAKOOK_01443 7.3e-22 yocD 3.4.17.13 V carboxypeptidase activity
KCCAKOOK_01444 1e-84 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KCCAKOOK_01447 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KCCAKOOK_01448 0.0 S Bacterial membrane protein, YfhO
KCCAKOOK_01449 2.2e-31 isaA GH23 M Immunodominant staphylococcal antigen A
KCCAKOOK_01452 3.6e-138 mreC M Involved in formation and maintenance of cell shape
KCCAKOOK_01453 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KCCAKOOK_01454 3.1e-94 usp 3.5.1.28 CBM50 S CHAP domain
KCCAKOOK_01455 2.2e-100 papP P ABC transporter (Permease
KCCAKOOK_01456 3.9e-106 P ABC transporter (Permease
KCCAKOOK_01457 7.6e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCCAKOOK_01458 1.1e-155 cjaA ET ABC transporter substrate-binding protein
KCCAKOOK_01459 3.4e-10 S TraX protein
KCCAKOOK_01460 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KCCAKOOK_01461 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KCCAKOOK_01462 7.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KCCAKOOK_01463 2.5e-32 csm6 S Psort location Cytoplasmic, score
KCCAKOOK_01464 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KCCAKOOK_01465 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCCAKOOK_01467 3e-182 ecsB U ABC transporter
KCCAKOOK_01468 2.3e-133 ecsA V abc transporter atp-binding protein
KCCAKOOK_01469 7.3e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KCCAKOOK_01472 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
KCCAKOOK_01476 8.1e-105 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KCCAKOOK_01477 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCCAKOOK_01478 3.4e-21 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KCCAKOOK_01479 1.8e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KCCAKOOK_01480 8.3e-31 amd 3.5.1.47 E Peptidase dimerisation domain
KCCAKOOK_01481 1.4e-203 oppD P Belongs to the ABC transporter superfamily
KCCAKOOK_01482 7e-167 amiD P ABC transporter (Permease
KCCAKOOK_01483 2.5e-18 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KCCAKOOK_01484 8.9e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCCAKOOK_01485 6.2e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KCCAKOOK_01486 3.2e-52 malX G maltose binding
KCCAKOOK_01487 4.5e-17 malX G maltose binding
KCCAKOOK_01488 2e-19 malX G ABC transporter
KCCAKOOK_01489 5.6e-178 malR K Transcriptional regulator
KCCAKOOK_01490 1.1e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KCCAKOOK_01491 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KCCAKOOK_01492 3.7e-09
KCCAKOOK_01493 1.1e-17
KCCAKOOK_01494 1.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
KCCAKOOK_01495 1.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KCCAKOOK_01496 0.0 pepN 3.4.11.2 E aminopeptidase
KCCAKOOK_01497 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
KCCAKOOK_01498 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCCAKOOK_01499 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCCAKOOK_01500 1.2e-155 pstA P phosphate transport system permease
KCCAKOOK_01501 2.3e-154 pstC P probably responsible for the translocation of the substrate across the membrane
KCCAKOOK_01502 4.3e-158 pstS P phosphate
KCCAKOOK_01503 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KCCAKOOK_01504 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KCCAKOOK_01505 1.9e-43 yktA S Belongs to the UPF0223 family
KCCAKOOK_01506 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KCCAKOOK_01507 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KCCAKOOK_01508 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KCCAKOOK_01509 4.7e-217 XK27_04775 S hemerythrin HHE cation binding domain
KCCAKOOK_01510 3.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KCCAKOOK_01511 6.5e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KCCAKOOK_01512 7.8e-61 S haloacid dehalogenase-like hydrolase
KCCAKOOK_01513 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
KCCAKOOK_01514 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KCCAKOOK_01515 1.8e-240 agcS E (Alanine) symporter
KCCAKOOK_01516 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KCCAKOOK_01517 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KCCAKOOK_01518 6.6e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KCCAKOOK_01519 1.5e-11 XK27_01265 S ECF-type riboflavin transporter, S component
KCCAKOOK_01520 1.3e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KCCAKOOK_01521 3.8e-43 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KCCAKOOK_01522 2e-86 S ECF-type riboflavin transporter, S component
KCCAKOOK_01524 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KCCAKOOK_01525 4.2e-181 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCCAKOOK_01526 2.3e-159 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCCAKOOK_01527 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KCCAKOOK_01528 9e-198 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCCAKOOK_01529 0.0 mdlB V abc transporter atp-binding protein
KCCAKOOK_01530 0.0 mdlA V abc transporter atp-binding protein
KCCAKOOK_01532 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
KCCAKOOK_01533 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KCCAKOOK_01534 3.6e-70 yutD J protein conserved in bacteria
KCCAKOOK_01535 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KCCAKOOK_01537 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KCCAKOOK_01538 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCCAKOOK_01539 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KCCAKOOK_01540 4.3e-47 ftsL D cell division protein FtsL
KCCAKOOK_01541 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KCCAKOOK_01542 2.6e-101
KCCAKOOK_01543 7.7e-35
KCCAKOOK_01544 8.7e-33 yhaI J Protein of unknown function (DUF805)
KCCAKOOK_01545 2.6e-18 D nuclear chromosome segregation
KCCAKOOK_01546 5.8e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCCAKOOK_01547 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KCCAKOOK_01548 2.2e-285 XK27_00765
KCCAKOOK_01549 8.1e-134 ecsA_2 V abc transporter atp-binding protein
KCCAKOOK_01550 5.2e-125 S Protein of unknown function (DUF554)
KCCAKOOK_01551 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KCCAKOOK_01552 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KCCAKOOK_01553 2.6e-121 liaI S membrane
KCCAKOOK_01554 6.7e-66 XK27_02470 K LytTr DNA-binding domain
KCCAKOOK_01555 2.8e-52 KT response to antibiotic
KCCAKOOK_01556 5.2e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
KCCAKOOK_01557 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
KCCAKOOK_01558 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KCCAKOOK_01559 2.1e-174 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCCAKOOK_01560 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KCCAKOOK_01561 1.6e-126 gntR1 K transcriptional
KCCAKOOK_01562 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KCCAKOOK_01563 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCCAKOOK_01564 4.1e-87 niaX
KCCAKOOK_01565 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
KCCAKOOK_01566 2.8e-128 K DNA-binding helix-turn-helix protein
KCCAKOOK_01567 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCCAKOOK_01568 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCCAKOOK_01569 4.1e-167 GK ROK family
KCCAKOOK_01570 3.5e-157 dprA LU DNA protecting protein DprA
KCCAKOOK_01571 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCCAKOOK_01572 2.5e-152 S TraX protein
KCCAKOOK_01573 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCCAKOOK_01574 2.4e-251 T PhoQ Sensor
KCCAKOOK_01575 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KCCAKOOK_01576 3.8e-153 XK27_05470 E Methionine synthase
KCCAKOOK_01577 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KCCAKOOK_01578 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCCAKOOK_01579 1.8e-51 IQ Acetoin reductase
KCCAKOOK_01580 3.9e-19 IQ Acetoin reductase
KCCAKOOK_01581 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KCCAKOOK_01582 2e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCCAKOOK_01585 7.9e-211 pqqE C radical SAM domain protein
KCCAKOOK_01586 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
KCCAKOOK_01587 6.6e-61 EGP Major facilitator Superfamily
KCCAKOOK_01588 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KCCAKOOK_01589 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KCCAKOOK_01590 6.7e-165 yocS S Transporter
KCCAKOOK_01591 5.8e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
KCCAKOOK_01592 2.9e-34 XK27_05000 S metal cluster binding
KCCAKOOK_01593 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KCCAKOOK_01594 8.7e-97
KCCAKOOK_01595 4.2e-16 estA E GDSL-like Lipase/Acylhydrolase
KCCAKOOK_01596 3.5e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
KCCAKOOK_01597 1e-31 K Cro/C1-type HTH DNA-binding domain
KCCAKOOK_01598 7e-46
KCCAKOOK_01599 8.9e-20
KCCAKOOK_01600 2.2e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCCAKOOK_01601 4.5e-97 mip S hydroperoxide reductase activity
KCCAKOOK_01602 2.4e-203 I acyl-CoA dehydrogenase
KCCAKOOK_01603 6.4e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
KCCAKOOK_01604 6.6e-249 msrR K Transcriptional regulator
KCCAKOOK_01605 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
KCCAKOOK_01606 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCCAKOOK_01607 9.8e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KCCAKOOK_01608 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KCCAKOOK_01609 3.2e-53 yheA S Belongs to the UPF0342 family
KCCAKOOK_01610 3.7e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KCCAKOOK_01611 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KCCAKOOK_01612 2.3e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KCCAKOOK_01613 4.1e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCCAKOOK_01614 3.3e-121 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KCCAKOOK_01615 9e-220 ywbD 2.1.1.191 J Methyltransferase
KCCAKOOK_01616 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KCCAKOOK_01617 2e-25 WQ51_00785
KCCAKOOK_01618 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KCCAKOOK_01619 3e-78 yueI S Protein of unknown function (DUF1694)
KCCAKOOK_01620 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KCCAKOOK_01621 6.6e-101 yyaQ V Protein conserved in bacteria
KCCAKOOK_01622 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KCCAKOOK_01623 3.5e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KCCAKOOK_01624 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
KCCAKOOK_01625 1.6e-30 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KCCAKOOK_01626 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KCCAKOOK_01627 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCCAKOOK_01629 1.6e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCCAKOOK_01630 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
KCCAKOOK_01631 2.4e-124 endA F DNA RNA non-specific endonuclease
KCCAKOOK_01632 6.5e-111 tcyB_2 P ABC transporter (permease)
KCCAKOOK_01633 5.9e-118 gltJ P ABC transporter (Permease
KCCAKOOK_01634 3.8e-148 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KCCAKOOK_01635 1.8e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCCAKOOK_01636 2.9e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCCAKOOK_01637 1.5e-247 vicK 2.7.13.3 T Histidine kinase
KCCAKOOK_01638 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KCCAKOOK_01639 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KCCAKOOK_01640 9.2e-147 yidA S hydrolases of the HAD superfamily
KCCAKOOK_01641 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
KCCAKOOK_01642 2.6e-67 ywiB S Domain of unknown function (DUF1934)
KCCAKOOK_01643 0.0 pacL 3.6.3.8 P cation transport ATPase
KCCAKOOK_01644 6.7e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KCCAKOOK_01645 1.3e-181 yjjH S Calcineurin-like phosphoesterase
KCCAKOOK_01646 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCCAKOOK_01647 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KCCAKOOK_01648 2.5e-124 ftsE D cell division ATP-binding protein FtsE
KCCAKOOK_01649 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KCCAKOOK_01650 1.7e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KCCAKOOK_01651 6.6e-178 yubA S permease
KCCAKOOK_01652 4.9e-224 G COG0457 FOG TPR repeat
KCCAKOOK_01653 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KCCAKOOK_01655 1.6e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KCCAKOOK_01656 7.6e-89 K transcriptional regulator
KCCAKOOK_01657 7.6e-36 yneF S UPF0154 protein
KCCAKOOK_01658 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KCCAKOOK_01659 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCCAKOOK_01660 3.5e-99 XK27_09740 S Phosphoesterase
KCCAKOOK_01661 7.8e-85 ykuL S CBS domain
KCCAKOOK_01662 1.8e-136 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KCCAKOOK_01663 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCCAKOOK_01664 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCCAKOOK_01665 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCCAKOOK_01666 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KCCAKOOK_01667 2.1e-258 trkH P Cation transport protein
KCCAKOOK_01668 6.5e-246 trkA P Potassium transporter peripheral membrane component
KCCAKOOK_01669 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KCCAKOOK_01670 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KCCAKOOK_01671 4.5e-112 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KCCAKOOK_01672 1.5e-161 K sequence-specific DNA binding
KCCAKOOK_01673 1.9e-33 V protein secretion by the type I secretion system
KCCAKOOK_01674 5.9e-107 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCCAKOOK_01675 1.6e-25 V protein secretion by the type I secretion system
KCCAKOOK_01676 1.8e-27 comA V protein secretion by the type I secretion system
KCCAKOOK_01677 1.5e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCCAKOOK_01678 8.3e-51 yhaI L Membrane
KCCAKOOK_01679 9.2e-132 S Domain of unknown function (DUF4173)
KCCAKOOK_01680 6.8e-95 ureI S AmiS/UreI family transporter
KCCAKOOK_01681 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KCCAKOOK_01682 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KCCAKOOK_01683 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KCCAKOOK_01684 6.6e-78 ureE O enzyme active site formation
KCCAKOOK_01685 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KCCAKOOK_01686 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KCCAKOOK_01687 2.2e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KCCAKOOK_01688 2.7e-177 cbiM P PDGLE domain
KCCAKOOK_01689 1.7e-137 P cobalt transport protein
KCCAKOOK_01690 1.6e-131 cbiO P ABC transporter
KCCAKOOK_01691 6.5e-202 yhjX P Major Facilitator
KCCAKOOK_01692 2e-169 corA P COG0598 Mg2 and Co2 transporters
KCCAKOOK_01693 3.1e-124 XK27_01040 S Pfam PF06570
KCCAKOOK_01695 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KCCAKOOK_01696 1e-90 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KCCAKOOK_01697 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KCCAKOOK_01698 3.6e-41 XK27_05745
KCCAKOOK_01699 2.5e-230 mutY L A G-specific adenine glycosylase
KCCAKOOK_01704 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCCAKOOK_01705 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KCCAKOOK_01706 1e-93 cvpA S toxin biosynthetic process
KCCAKOOK_01707 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KCCAKOOK_01708 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCCAKOOK_01709 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KCCAKOOK_01710 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KCCAKOOK_01711 2e-47 azlD E branched-chain amino acid
KCCAKOOK_01712 5.2e-114 azlC E AzlC protein
KCCAKOOK_01713 4.3e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KCCAKOOK_01714 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KCCAKOOK_01715 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KCCAKOOK_01716 2.5e-33 ykzG S Belongs to the UPF0356 family
KCCAKOOK_01717 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCCAKOOK_01718 5.5e-41 pscB M CHAP domain protein
KCCAKOOK_01719 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
KCCAKOOK_01720 8.5e-63 glnR K Transcriptional regulator
KCCAKOOK_01721 1.3e-87 S Fusaric acid resistance protein-like
KCCAKOOK_01722 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KCCAKOOK_01723 4.6e-42 fnt P Formate nitrite transporter
KCCAKOOK_01724 1.1e-76 XK27_08585 S Psort location CytoplasmicMembrane, score
KCCAKOOK_01725 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCCAKOOK_01726 5.8e-79 T PhoQ Sensor
KCCAKOOK_01727 6.5e-43 T PhoQ Sensor
KCCAKOOK_01728 1.4e-39 T PhoQ Sensor
KCCAKOOK_01729 1.4e-65 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCCAKOOK_01730 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KCCAKOOK_01731 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KCCAKOOK_01732 2.2e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCCAKOOK_01733 1.7e-94 panT S ECF transporter, substrate-specific component
KCCAKOOK_01734 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KCCAKOOK_01735 7.3e-166 metF 1.5.1.20 C reductase
KCCAKOOK_01736 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KCCAKOOK_01738 7.9e-216 sip L Belongs to the 'phage' integrase family
KCCAKOOK_01739 6.5e-21 xre K Cro/C1-type HTH DNA-binding domain
KCCAKOOK_01740 1.8e-19 K Cro/C1-type HTH DNA-binding domain
KCCAKOOK_01744 3.2e-15
KCCAKOOK_01745 3.1e-22
KCCAKOOK_01746 6.1e-141 KL Phage plasmid primase P4 family
KCCAKOOK_01747 3.8e-287 S DNA primase
KCCAKOOK_01749 1.7e-12
KCCAKOOK_01751 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KCCAKOOK_01752 0.0 3.6.3.8 P cation transport ATPase
KCCAKOOK_01753 7.9e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCCAKOOK_01754 1.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KCCAKOOK_01756 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KCCAKOOK_01757 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCCAKOOK_01758 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KCCAKOOK_01759 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KCCAKOOK_01760 6.4e-29 2.3.1.128 K acetyltransferase
KCCAKOOK_01761 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KCCAKOOK_01762 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KCCAKOOK_01763 1.4e-130 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCCAKOOK_01764 2.6e-64 WQ51_03320 S cog cog4835
KCCAKOOK_01765 6.4e-61 XK27_08360 S EDD domain protein, DegV family
KCCAKOOK_01766 5.5e-75 XK27_08360 S EDD domain protein, DegV family
KCCAKOOK_01767 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KCCAKOOK_01768 4.3e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KCCAKOOK_01769 0.0 yfmR S abc transporter atp-binding protein
KCCAKOOK_01770 1.6e-24 U response to pH
KCCAKOOK_01771 9e-77 3.6.1.13, 3.6.1.55 F Nudix family
KCCAKOOK_01772 2.7e-43 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KCCAKOOK_01773 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KCCAKOOK_01774 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KCCAKOOK_01775 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KCCAKOOK_01776 1.9e-77 K DNA-binding transcription factor activity
KCCAKOOK_01777 0.0 lmrA1 V abc transporter atp-binding protein
KCCAKOOK_01778 9.3e-72 S Signal peptide protein, YSIRK family
KCCAKOOK_01779 1.4e-54 K response regulator
KCCAKOOK_01780 2e-45 cah 4.2.1.1 P carbonic anhydrase
KCCAKOOK_01781 1.3e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCCAKOOK_01782 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
KCCAKOOK_01783 2.8e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)