ORF_ID e_value Gene_name EC_number CAZy COGs Description
PHGHKPIB_00001 0.0 lacL 3.2.1.23 G -beta-galactosidase
PHGHKPIB_00002 0.0 lacS G transporter
PHGHKPIB_00003 3.3e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PHGHKPIB_00004 1.9e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PHGHKPIB_00005 1.7e-218 KLT Protein tyrosine kinase
PHGHKPIB_00006 1.2e-94 tnp* L An automated process has identified a potential problem with this gene model
PHGHKPIB_00007 4.1e-130 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
PHGHKPIB_00008 6.5e-29 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PHGHKPIB_00009 2.5e-20 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PHGHKPIB_00010 1.6e-46 fruR K transcriptional
PHGHKPIB_00011 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PHGHKPIB_00012 5.3e-163 T Diguanylate cyclase
PHGHKPIB_00013 1.4e-19 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PHGHKPIB_00014 2.4e-07 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PHGHKPIB_00015 1.4e-44 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PHGHKPIB_00016 7.2e-28 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PHGHKPIB_00017 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PHGHKPIB_00018 3e-216 ftsW D Belongs to the SEDS family
PHGHKPIB_00019 7.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PHGHKPIB_00020 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PHGHKPIB_00021 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PHGHKPIB_00022 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PHGHKPIB_00023 8.7e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHGHKPIB_00024 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PHGHKPIB_00025 3.4e-121 atpB C it plays a direct role in the translocation of protons across the membrane
PHGHKPIB_00026 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHGHKPIB_00027 2e-267
PHGHKPIB_00028 6.8e-218 dcm 2.1.1.37 H cytosine-specific methyltransferase
PHGHKPIB_00029 1e-18 S DNA-sulfur modification-associated
PHGHKPIB_00031 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PHGHKPIB_00032 7.1e-93 F AAA domain
PHGHKPIB_00033 2.4e-101 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
PHGHKPIB_00034 2.9e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PHGHKPIB_00035 6.1e-15 coiA 3.6.4.12 S Competence protein
PHGHKPIB_00036 2.2e-15 T peptidase
PHGHKPIB_00037 4.8e-149 rarD S Transporter
PHGHKPIB_00038 4.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PHGHKPIB_00039 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PHGHKPIB_00040 1.1e-134 yxkH G deacetylase
PHGHKPIB_00041 1.3e-207 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PHGHKPIB_00042 2.1e-126 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PHGHKPIB_00043 1e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PHGHKPIB_00044 3.8e-182 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PHGHKPIB_00045 6.3e-221 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
PHGHKPIB_00046 2.9e-137 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PHGHKPIB_00047 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
PHGHKPIB_00048 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PHGHKPIB_00051 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PHGHKPIB_00052 1.7e-84 yxjI S LURP-one-related
PHGHKPIB_00053 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
PHGHKPIB_00054 6.7e-119 yrrM 2.1.1.104 S O-Methyltransferase
PHGHKPIB_00055 5.9e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
PHGHKPIB_00056 0.0 pepF E oligoendopeptidase F
PHGHKPIB_00057 2.6e-164 coiA 3.6.4.12 S Competence protein
PHGHKPIB_00058 3.6e-274 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PHGHKPIB_00059 8e-105 S CAAX amino terminal protease family protein
PHGHKPIB_00060 4.7e-168 K transcriptional regulator (lysR family)
PHGHKPIB_00061 4.9e-159 S reductase
PHGHKPIB_00062 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PHGHKPIB_00066 5.2e-190 phoH T phosphate starvation-inducible protein PhoH
PHGHKPIB_00067 1.3e-123 sip M LysM domain protein
PHGHKPIB_00068 3.7e-34 yozE S Belongs to the UPF0346 family
PHGHKPIB_00069 1e-159 cvfB S Protein conserved in bacteria
PHGHKPIB_00070 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PHGHKPIB_00071 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PHGHKPIB_00072 1.2e-214 sptS 2.7.13.3 T Histidine kinase
PHGHKPIB_00073 8.3e-117 T response regulator
PHGHKPIB_00074 5.7e-112 2.7.6.5 S Region found in RelA / SpoT proteins
PHGHKPIB_00075 4.3e-112 K Acetyltransferase (GNAT) family
PHGHKPIB_00076 0.0 lmrA2 V abc transporter atp-binding protein
PHGHKPIB_00077 0.0 lmrA1 V abc transporter atp-binding protein
PHGHKPIB_00078 1.7e-73 K DNA-binding transcription factor activity
PHGHKPIB_00079 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PHGHKPIB_00080 5.2e-282 S Psort location CytoplasmicMembrane, score
PHGHKPIB_00081 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PHGHKPIB_00082 2.6e-208 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
PHGHKPIB_00083 1.6e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
PHGHKPIB_00084 1e-26 U response to pH
PHGHKPIB_00085 0.0 yfmR S abc transporter atp-binding protein
PHGHKPIB_00086 1.3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PHGHKPIB_00087 1.1e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PHGHKPIB_00088 6.2e-146 XK27_08360 S EDD domain protein, DegV family
PHGHKPIB_00089 5e-63 WQ51_03320 S cog cog4835
PHGHKPIB_00090 4.2e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PHGHKPIB_00091 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PHGHKPIB_00092 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PHGHKPIB_00093 3.1e-55 2.3.1.128 K acetyltransferase
PHGHKPIB_00094 6.9e-31 yegS 2.7.1.107 I Diacylglycerol kinase
PHGHKPIB_00095 3.5e-123 ybbA S Putative esterase
PHGHKPIB_00096 2.1e-172 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PHGHKPIB_00097 8.3e-134 fecE 3.6.3.34 HP ABC transporter
PHGHKPIB_00098 1.8e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PHGHKPIB_00099 3.7e-118 V CAAX protease self-immunity
PHGHKPIB_00100 3.5e-149 S Domain of unknown function (DUF4300)
PHGHKPIB_00101 5.3e-90 tetR K transcriptional regulator
PHGHKPIB_00102 7.3e-290 norB P Major facilitator superfamily
PHGHKPIB_00103 7.1e-21 S Domain of unknown function (DUF4767)
PHGHKPIB_00105 5.4e-110 cutC P Participates in the control of copper homeostasis
PHGHKPIB_00106 5.2e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
PHGHKPIB_00107 4.2e-150 yitS S EDD domain protein, DegV family
PHGHKPIB_00108 7e-204 yeaN P transporter
PHGHKPIB_00109 5.8e-132 S Domain of unknown function (DUF4336)
PHGHKPIB_00110 1.5e-141 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PHGHKPIB_00112 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PHGHKPIB_00113 1.6e-61 smtB K Transcriptional regulator
PHGHKPIB_00114 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
PHGHKPIB_00115 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
PHGHKPIB_00116 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PHGHKPIB_00117 5.9e-55
PHGHKPIB_00118 8.7e-60
PHGHKPIB_00119 1.1e-49
PHGHKPIB_00120 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
PHGHKPIB_00121 2e-217 EGP Transmembrane secretion effector
PHGHKPIB_00122 4.3e-22
PHGHKPIB_00123 2e-101 L DNA alkylation repair enzyme
PHGHKPIB_00124 1.7e-162 aph 2.7.11.1 KLT Aminoglycoside phosphotransferase
PHGHKPIB_00125 6.2e-52 K Transcriptional regulator
PHGHKPIB_00126 6.6e-31 S Protein of unknown function (DUF1648)
PHGHKPIB_00127 5.2e-255 6.1.1.6 S Psort location CytoplasmicMembrane, score
PHGHKPIB_00128 5.3e-130 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
PHGHKPIB_00129 1.3e-105 K Transcriptional regulator
PHGHKPIB_00130 2e-92 L Molecular Function DNA binding, Biological Process DNA recombination
PHGHKPIB_00131 4.8e-45 L transposase activity
PHGHKPIB_00132 2.5e-91 Q Nodulation protein S (NodS)
PHGHKPIB_00133 5.1e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHGHKPIB_00134 2e-97 mip S hydroperoxide reductase activity
PHGHKPIB_00135 1.9e-200 I acyl-CoA dehydrogenase
PHGHKPIB_00136 4.6e-150 ydiA P C4-dicarboxylate transporter malic acid transport
PHGHKPIB_00137 1.9e-248 msrR K Transcriptional regulator
PHGHKPIB_00138 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
PHGHKPIB_00139 1e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PHGHKPIB_00140 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PHGHKPIB_00141 3.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PHGHKPIB_00142 4.2e-53 yheA S Belongs to the UPF0342 family
PHGHKPIB_00143 5e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PHGHKPIB_00144 1.7e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PHGHKPIB_00145 5.4e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PHGHKPIB_00146 5.3e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PHGHKPIB_00147 5.8e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PHGHKPIB_00148 1.7e-218 ywbD 2.1.1.191 J Methyltransferase
PHGHKPIB_00149 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PHGHKPIB_00150 4.6e-25 WQ51_00785
PHGHKPIB_00151 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHGHKPIB_00152 3.1e-75 yueI S Protein of unknown function (DUF1694)
PHGHKPIB_00153 2.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PHGHKPIB_00154 3.6e-199 yyaQ S YjbR
PHGHKPIB_00155 2.4e-181 ccpA K Catabolite control protein A
PHGHKPIB_00156 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
PHGHKPIB_00157 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
PHGHKPIB_00158 5.7e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PHGHKPIB_00159 1.9e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PHGHKPIB_00160 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PHGHKPIB_00161 2e-33 secG U Preprotein translocase subunit SecG
PHGHKPIB_00162 2.1e-219 mdtG EGP Major facilitator Superfamily
PHGHKPIB_00163 1.3e-94 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PHGHKPIB_00164 1.1e-147 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PHGHKPIB_00165 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PHGHKPIB_00166 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PHGHKPIB_00167 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PHGHKPIB_00168 7.1e-150 licT K antiterminator
PHGHKPIB_00169 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PHGHKPIB_00170 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
PHGHKPIB_00171 1.2e-146 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PHGHKPIB_00172 2e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PHGHKPIB_00173 3.5e-151 I Alpha/beta hydrolase family
PHGHKPIB_00174 6.6e-08
PHGHKPIB_00175 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PHGHKPIB_00176 9.1e-78 feoA P FeoA domain protein
PHGHKPIB_00177 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
PHGHKPIB_00178 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
PHGHKPIB_00179 1.1e-33 ykuJ S protein conserved in bacteria
PHGHKPIB_00180 4.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PHGHKPIB_00181 0.0 clpE O Belongs to the ClpA ClpB family
PHGHKPIB_00182 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PHGHKPIB_00183 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
PHGHKPIB_00184 4.3e-277 pepD E Dipeptidase
PHGHKPIB_00185 1.3e-160 whiA K May be required for sporulation
PHGHKPIB_00186 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PHGHKPIB_00187 8.5e-162 rapZ S Displays ATPase and GTPase activities
PHGHKPIB_00188 3.1e-136 yejC S cyclic nucleotide-binding protein
PHGHKPIB_00189 1.1e-198 D nuclear chromosome segregation
PHGHKPIB_00190 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
PHGHKPIB_00191 2.7e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PHGHKPIB_00192 1.4e-80 queD 4.1.2.50, 4.2.3.12 H synthase
PHGHKPIB_00193 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PHGHKPIB_00194 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
PHGHKPIB_00195 1.5e-201 pmrB EGP Major facilitator Superfamily
PHGHKPIB_00196 2.8e-19
PHGHKPIB_00197 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PHGHKPIB_00198 7e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PHGHKPIB_00199 1.1e-81 ypmB S Protein conserved in bacteria
PHGHKPIB_00200 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PHGHKPIB_00201 2.3e-113 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PHGHKPIB_00202 3.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
PHGHKPIB_00203 2.6e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
PHGHKPIB_00204 1.6e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PHGHKPIB_00205 3.2e-187 tcsA S membrane
PHGHKPIB_00206 4.5e-62 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PHGHKPIB_00207 2.1e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PHGHKPIB_00208 1e-232 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PHGHKPIB_00209 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
PHGHKPIB_00210 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
PHGHKPIB_00211 1e-29 rpsT J Binds directly to 16S ribosomal RNA
PHGHKPIB_00212 9.8e-237 T PhoQ Sensor
PHGHKPIB_00213 6.1e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PHGHKPIB_00214 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PHGHKPIB_00215 6.9e-111 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
PHGHKPIB_00216 1.1e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PHGHKPIB_00217 9.2e-93 panT S ECF transporter, substrate-specific component
PHGHKPIB_00218 3.8e-91 panT S Psort location CytoplasmicMembrane, score
PHGHKPIB_00219 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PHGHKPIB_00220 1.6e-165 metF 1.5.1.20 E reductase
PHGHKPIB_00221 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PHGHKPIB_00223 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
PHGHKPIB_00224 0.0 3.6.3.8 P cation transport ATPase
PHGHKPIB_00225 5.3e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PHGHKPIB_00226 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHGHKPIB_00227 1.2e-235 dltB M Membrane protein involved in D-alanine export
PHGHKPIB_00228 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHGHKPIB_00229 0.0 XK27_10035 V abc transporter atp-binding protein
PHGHKPIB_00230 8e-289 yfiB1 V abc transporter atp-binding protein
PHGHKPIB_00231 1.4e-99 pvaA M lytic transglycosylase activity
PHGHKPIB_00232 5.5e-178 ndpA S 37-kD nucleoid-associated bacterial protein
PHGHKPIB_00233 1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PHGHKPIB_00234 4.4e-101 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PHGHKPIB_00235 2.5e-131 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PHGHKPIB_00236 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PHGHKPIB_00237 5.1e-110 tdk 2.7.1.21 F thymidine kinase
PHGHKPIB_00238 4.9e-182 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PHGHKPIB_00239 1.2e-151 gst O Glutathione S-transferase
PHGHKPIB_00240 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
PHGHKPIB_00241 1e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHGHKPIB_00242 3.8e-40 rpmE2 J 50S ribosomal protein L31
PHGHKPIB_00243 6.1e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
PHGHKPIB_00244 7.6e-164 ypuA S secreted protein
PHGHKPIB_00245 9.1e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
PHGHKPIB_00246 1.7e-126 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
PHGHKPIB_00247 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHGHKPIB_00248 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PHGHKPIB_00249 6.6e-254 noxE P NADH oxidase
PHGHKPIB_00250 4.3e-294 yfmM S abc transporter atp-binding protein
PHGHKPIB_00251 2.8e-83 XK27_01265 S ECF-type riboflavin transporter, S component
PHGHKPIB_00252 2.6e-152 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
PHGHKPIB_00253 2.2e-85 S ECF-type riboflavin transporter, S component
PHGHKPIB_00255 7.9e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PHGHKPIB_00256 2.2e-91 yocS S Transporter
PHGHKPIB_00257 0.0 hscC O Belongs to the heat shock protein 70 family
PHGHKPIB_00258 3.9e-198 anK3 G response to abiotic stimulus
PHGHKPIB_00260 6.4e-42 1.13.11.2 S glyoxalase
PHGHKPIB_00261 1.4e-107 XK27_02070 S nitroreductase
PHGHKPIB_00262 2.7e-27
PHGHKPIB_00263 2.5e-27 XK27_07105 K transcriptional
PHGHKPIB_00264 1.1e-06 S Protein of unknown function (DUF3169)
PHGHKPIB_00265 3.7e-168 ydhF S Aldo keto reductase
PHGHKPIB_00266 6.3e-93 pat 2.3.1.183 M acetyltransferase
PHGHKPIB_00267 4.9e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHGHKPIB_00268 5.8e-172 S oxidoreductase
PHGHKPIB_00269 1.7e-229 murN 2.3.2.16 V FemAB family
PHGHKPIB_00270 1.3e-117 M Pfam SNARE associated Golgi protein
PHGHKPIB_00271 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
PHGHKPIB_00274 1.4e-204 rpsA 1.17.7.4 J ribosomal protein S1
PHGHKPIB_00277 6.3e-16 S Protein of unknown function (DUF2969)
PHGHKPIB_00278 1.8e-200 ilvE 2.6.1.42 E Aminotransferase
PHGHKPIB_00279 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHGHKPIB_00280 7.6e-09
PHGHKPIB_00282 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHGHKPIB_00283 2.8e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PHGHKPIB_00284 2.1e-13 L Helix-hairpin-helix DNA-binding motif class 1
PHGHKPIB_00285 6.5e-30 S Domain of unknown function (DUF1912)
PHGHKPIB_00286 1.4e-162 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
PHGHKPIB_00287 3.4e-214 mmuP E amino acid
PHGHKPIB_00288 2.2e-23 mmuP E amino acid
PHGHKPIB_00289 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PHGHKPIB_00290 7.5e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PHGHKPIB_00291 9.7e-22
PHGHKPIB_00292 8.4e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PHGHKPIB_00293 3.2e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PHGHKPIB_00294 1.3e-210 mvaS 2.3.3.10 I synthase
PHGHKPIB_00295 7.7e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PHGHKPIB_00296 1.1e-77 K hmm pf08876
PHGHKPIB_00297 5.2e-119 yqfA K protein, Hemolysin III
PHGHKPIB_00298 9.2e-29 pspC KT PspC domain protein
PHGHKPIB_00299 5.1e-198 S Protein of unknown function (DUF3114)
PHGHKPIB_00300 1.4e-151 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PHGHKPIB_00301 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PHGHKPIB_00302 1.1e-12
PHGHKPIB_00303 9.5e-242 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PHGHKPIB_00304 1.8e-189 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
PHGHKPIB_00305 0.0 U protein secretion
PHGHKPIB_00306 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PHGHKPIB_00307 3.5e-23
PHGHKPIB_00308 2.2e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
PHGHKPIB_00309 2.9e-257 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PHGHKPIB_00311 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
PHGHKPIB_00312 2.2e-51 S ABC-2 family transporter protein
PHGHKPIB_00313 2.1e-149 V ABC transporter, ATP-binding protein
PHGHKPIB_00314 3.6e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PHGHKPIB_00315 3.9e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PHGHKPIB_00316 5.1e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PHGHKPIB_00317 4.2e-153 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PHGHKPIB_00318 1.3e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PHGHKPIB_00319 1e-145 E Alpha beta hydrolase
PHGHKPIB_00321 8.9e-201 ald 1.4.1.1 C Belongs to the AlaDH PNT family
PHGHKPIB_00322 1e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PHGHKPIB_00323 6.1e-43 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PHGHKPIB_00324 9.5e-77 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PHGHKPIB_00325 6.6e-114 S VIT family
PHGHKPIB_00326 1.5e-196 yceA S Belongs to the UPF0176 family
PHGHKPIB_00327 2.4e-51 S Protein conserved in bacteria
PHGHKPIB_00328 2.3e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PHGHKPIB_00329 1.9e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PHGHKPIB_00330 0.0 lmrA V abc transporter atp-binding protein
PHGHKPIB_00331 0.0 mdlB V abc transporter atp-binding protein
PHGHKPIB_00332 1.3e-134 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
PHGHKPIB_00333 2.1e-117 ylfI S tigr01906
PHGHKPIB_00334 3e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PHGHKPIB_00335 2.4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
PHGHKPIB_00336 3.2e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
PHGHKPIB_00337 2.2e-30 KT response to antibiotic
PHGHKPIB_00339 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PHGHKPIB_00340 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PHGHKPIB_00341 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PHGHKPIB_00342 6.9e-256 S phospholipase Carboxylesterase
PHGHKPIB_00343 1.4e-195 yurR 1.4.5.1 E oxidoreductase
PHGHKPIB_00344 7e-142 zupT P Mediates zinc uptake. May also transport other divalent cations
PHGHKPIB_00345 9.6e-141 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PHGHKPIB_00346 1.3e-120 trmK 2.1.1.217 S SAM-dependent methyltransferase
PHGHKPIB_00347 1.3e-64 gtrA S GtrA-like protein
PHGHKPIB_00348 2.4e-248 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PHGHKPIB_00349 1.1e-162 ybbR S Protein conserved in bacteria
PHGHKPIB_00350 7.9e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PHGHKPIB_00351 7.1e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
PHGHKPIB_00352 1.3e-148 cobQ S glutamine amidotransferase
PHGHKPIB_00353 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHGHKPIB_00354 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
PHGHKPIB_00355 2.7e-39 MA20_06245 S yiaA/B two helix domain
PHGHKPIB_00356 0.0 uup S abc transporter atp-binding protein
PHGHKPIB_00357 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
PHGHKPIB_00358 5.1e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
PHGHKPIB_00359 1.9e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
PHGHKPIB_00360 2.7e-153 XK27_05675 S Esterase
PHGHKPIB_00361 6.1e-162 XK27_05670 S Putative esterase
PHGHKPIB_00362 1.5e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
PHGHKPIB_00363 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PHGHKPIB_00364 3e-38 ptsH G phosphocarrier protein Hpr
PHGHKPIB_00365 1.3e-218 icd 1.1.1.42 C Isocitrate dehydrogenase
PHGHKPIB_00366 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
PHGHKPIB_00367 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PHGHKPIB_00368 2.2e-34 nrdH O Glutaredoxin
PHGHKPIB_00369 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHGHKPIB_00370 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHGHKPIB_00371 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PHGHKPIB_00372 8.4e-138 divIVA D Cell division initiation protein
PHGHKPIB_00373 1.9e-144 ylmH S conserved protein, contains S4-like domain
PHGHKPIB_00374 2.9e-30 yggT D integral membrane protein
PHGHKPIB_00375 2.2e-86 sepF D cell septum assembly
PHGHKPIB_00376 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PHGHKPIB_00377 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PHGHKPIB_00378 1.6e-223 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PHGHKPIB_00379 3.7e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PHGHKPIB_00380 1.2e-197 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PHGHKPIB_00381 9.7e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PHGHKPIB_00383 0.0 typA T GTP-binding protein TypA
PHGHKPIB_00384 2.7e-177 glk 2.7.1.2 G Glucokinase
PHGHKPIB_00385 7.1e-27 yqgQ S protein conserved in bacteria
PHGHKPIB_00386 2.2e-78 perR P Belongs to the Fur family
PHGHKPIB_00387 3.3e-89 dps P Belongs to the Dps family
PHGHKPIB_00388 2.7e-104 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
PHGHKPIB_00389 1.8e-24 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PHGHKPIB_00390 1.6e-06
PHGHKPIB_00393 5.7e-117 nudL L hydrolase
PHGHKPIB_00394 1.8e-53 K transcriptional regulator, PadR family
PHGHKPIB_00395 2.4e-64 XK27_06920 S Protein of unknown function (DUF1700)
PHGHKPIB_00396 3.9e-108 S Putative adhesin
PHGHKPIB_00397 2.1e-159 XK27_06930 V domain protein
PHGHKPIB_00398 9.9e-97 XK27_06935 K transcriptional regulator
PHGHKPIB_00399 1.6e-53 ypaA M Membrane
PHGHKPIB_00400 1.9e-10
PHGHKPIB_00401 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PHGHKPIB_00402 1.8e-47 veg S Biofilm formation stimulator VEG
PHGHKPIB_00403 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PHGHKPIB_00404 2.2e-73 rplI J binds to the 23S rRNA
PHGHKPIB_00405 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PHGHKPIB_00406 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PHGHKPIB_00407 2.4e-99 yvbG U UPF0056 membrane protein
PHGHKPIB_00408 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PHGHKPIB_00409 2.4e-311 S Bacterial membrane protein, YfhO
PHGHKPIB_00410 8.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
PHGHKPIB_00411 1e-70 lytE M LysM domain protein
PHGHKPIB_00412 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHGHKPIB_00413 6.2e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHGHKPIB_00414 1.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHGHKPIB_00415 1.2e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PHGHKPIB_00416 1.4e-129 S sequence-specific DNA binding
PHGHKPIB_00417 1.1e-231 ymfH S Peptidase M16
PHGHKPIB_00418 6.7e-229 ymfF S Peptidase M16
PHGHKPIB_00419 4.9e-58 yaaA S S4 domain protein YaaA
PHGHKPIB_00420 5.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PHGHKPIB_00421 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PHGHKPIB_00422 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PHGHKPIB_00423 7.8e-152 yvjA S membrane
PHGHKPIB_00424 1.1e-305 ybiT S abc transporter atp-binding protein
PHGHKPIB_00425 0.0 XK27_10405 S Bacterial membrane protein YfhO
PHGHKPIB_00429 4e-119 yoaK S Protein of unknown function (DUF1275)
PHGHKPIB_00430 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PHGHKPIB_00431 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
PHGHKPIB_00432 7.7e-135 parB K Belongs to the ParB family
PHGHKPIB_00433 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PHGHKPIB_00434 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PHGHKPIB_00435 1.1e-29 yyzM S Protein conserved in bacteria
PHGHKPIB_00436 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PHGHKPIB_00437 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PHGHKPIB_00438 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PHGHKPIB_00439 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PHGHKPIB_00440 3e-60 divIC D Septum formation initiator
PHGHKPIB_00442 2.1e-233 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
PHGHKPIB_00443 9.7e-236 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PHGHKPIB_00444 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PHGHKPIB_00445 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PHGHKPIB_00446 0.0 rafA 3.2.1.22 G alpha-galactosidase
PHGHKPIB_00447 6.4e-150 galR K Transcriptional regulator
PHGHKPIB_00448 6.2e-30 XK27_00530 M CHAP domain protein
PHGHKPIB_00449 1.7e-102 abiGI K Transcriptional regulator, AbiEi antitoxin
PHGHKPIB_00450 2.2e-274 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
PHGHKPIB_00451 4.6e-29 K DNA-binding transcription factor activity
PHGHKPIB_00452 2.6e-211 S Tetratricopeptide repeat
PHGHKPIB_00453 9.2e-158 yvgN C reductase
PHGHKPIB_00454 1.1e-30 XK27_10490
PHGHKPIB_00455 1.1e-40 DJ nuclease activity
PHGHKPIB_00456 1.3e-20 S Antitoxin component of a toxin-antitoxin (TA) module
PHGHKPIB_00458 5.9e-132 agrA KT Response regulator of the LytR AlgR family
PHGHKPIB_00459 6.5e-227 2.7.13.3 T GHKL domain
PHGHKPIB_00462 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PHGHKPIB_00463 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PHGHKPIB_00464 1.4e-202 V permease protein
PHGHKPIB_00465 1.5e-121 macB V ABC transporter, ATP-binding protein
PHGHKPIB_00466 3.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PHGHKPIB_00467 2.2e-126 2.1.1.223 S Putative SAM-dependent methyltransferase
PHGHKPIB_00468 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
PHGHKPIB_00469 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
PHGHKPIB_00470 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PHGHKPIB_00471 1.8e-221 pyrP F uracil Permease
PHGHKPIB_00472 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHGHKPIB_00473 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PHGHKPIB_00474 8.3e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PHGHKPIB_00475 4e-167 fhuR K transcriptional regulator (lysR family)
PHGHKPIB_00477 1.3e-43
PHGHKPIB_00478 1.4e-67 K Helix-turn-helix
PHGHKPIB_00481 1.3e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PHGHKPIB_00482 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PHGHKPIB_00483 2.9e-10 uvrX 2.7.7.7 L impB/mucB/samB family
PHGHKPIB_00484 8.7e-254 cycA E permease
PHGHKPIB_00485 1.7e-38 ynzC S UPF0291 protein
PHGHKPIB_00486 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PHGHKPIB_00487 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PHGHKPIB_00488 6.6e-221 S membrane
PHGHKPIB_00489 4.4e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PHGHKPIB_00490 1e-293 nptA P COG1283 Na phosphate symporter
PHGHKPIB_00491 8e-114 3.4.17.14, 3.5.1.28 NU amidase activity
PHGHKPIB_00492 1.8e-82 S Bacterial inner membrane protein
PHGHKPIB_00493 1.1e-142 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
PHGHKPIB_00494 1.7e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
PHGHKPIB_00495 9.5e-53 glnB K Belongs to the P(II) protein family
PHGHKPIB_00496 5e-229 amt P Ammonium Transporter
PHGHKPIB_00497 6.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PHGHKPIB_00498 1.2e-54 yabA L Involved in initiation control of chromosome replication
PHGHKPIB_00499 6.4e-132 yaaT S stage 0 sporulation protein
PHGHKPIB_00500 3.3e-158 holB 2.7.7.7 L dna polymerase iii
PHGHKPIB_00501 2.9e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PHGHKPIB_00503 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PHGHKPIB_00504 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PHGHKPIB_00505 0.0 V ABC transporter (Permease
PHGHKPIB_00506 4.3e-124 V abc transporter atp-binding protein
PHGHKPIB_00507 2e-92 tetR K transcriptional regulator
PHGHKPIB_00508 1.6e-52 S Phenazine biosynthesis protein
PHGHKPIB_00509 2.3e-72 S Phenazine biosynthesis protein
PHGHKPIB_00510 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
PHGHKPIB_00511 3.5e-74 cbiQ P cobalt transport
PHGHKPIB_00512 1e-156 P abc transporter atp-binding protein
PHGHKPIB_00513 9.7e-149 cbiO2 P ABC transporter, ATP-binding protein
PHGHKPIB_00514 8.8e-113 tnp L DDE domain
PHGHKPIB_00515 7e-11
PHGHKPIB_00516 1.7e-68 S Protein of unknown function with HXXEE motif
PHGHKPIB_00517 4.2e-95 K Transcriptional regulator, TetR family
PHGHKPIB_00518 2.9e-157 czcD P cation diffusion facilitator family transporter
PHGHKPIB_00519 4.2e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PHGHKPIB_00520 3.4e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
PHGHKPIB_00521 3.5e-241 S the current gene model (or a revised gene model) may contain a frame shift
PHGHKPIB_00522 1.1e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
PHGHKPIB_00523 0.0 V Type III restriction enzyme, res subunit
PHGHKPIB_00524 4.1e-178 yclQ P ABC-type enterochelin transport system, periplasmic component
PHGHKPIB_00525 1.6e-233 dinF V Mate efflux family protein
PHGHKPIB_00526 6.2e-277 S Psort location CytoplasmicMembrane, score
PHGHKPIB_00527 1.4e-306 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PHGHKPIB_00528 1.4e-134 S TraX protein
PHGHKPIB_00529 2e-92 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
PHGHKPIB_00530 1.5e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PHGHKPIB_00531 9.4e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PHGHKPIB_00532 1.6e-180 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHGHKPIB_00533 1.6e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHGHKPIB_00534 1.6e-129 cas6 S Pfam:DUF2276
PHGHKPIB_00535 0.0 csm1 S CRISPR-associated protein Csm1 family
PHGHKPIB_00536 7.3e-62 csm2 L Pfam:DUF310
PHGHKPIB_00537 2.4e-116 csm3 L RAMP superfamily
PHGHKPIB_00538 3.7e-165 csm4 L CRISPR-associated RAMP protein, Csm4 family
PHGHKPIB_00539 4.1e-203 csm5 L CRISPR-associated RAMP protein, Csm5 family
PHGHKPIB_00540 3.9e-114 csm6 S Psort location Cytoplasmic, score
PHGHKPIB_00541 1e-147 csm6 S Psort location Cytoplasmic, score
PHGHKPIB_00542 2.2e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PHGHKPIB_00543 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PHGHKPIB_00544 4.7e-242 nylA 3.5.1.4 J Belongs to the amidase family
PHGHKPIB_00545 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
PHGHKPIB_00546 6.4e-82 yecS P ABC transporter (Permease
PHGHKPIB_00547 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
PHGHKPIB_00548 1.3e-176 bglC K Transcriptional regulator
PHGHKPIB_00549 1e-243 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PHGHKPIB_00550 5.8e-239 agcS E (Alanine) symporter
PHGHKPIB_00551 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PHGHKPIB_00552 5.6e-239 metY 2.5.1.49 E o-acetylhomoserine
PHGHKPIB_00553 4.7e-137 S haloacid dehalogenase-like hydrolase
PHGHKPIB_00554 7.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PHGHKPIB_00555 4.8e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
PHGHKPIB_00556 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
PHGHKPIB_00557 1.8e-243 XK27_04775 S hemerythrin HHE cation binding domain
PHGHKPIB_00558 1.5e-153 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PHGHKPIB_00559 4e-167 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PHGHKPIB_00560 7.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PHGHKPIB_00561 1.5e-43 yktA S Belongs to the UPF0223 family
PHGHKPIB_00562 1.3e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PHGHKPIB_00563 8.5e-251 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PHGHKPIB_00564 9e-156 pstS P phosphate
PHGHKPIB_00565 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
PHGHKPIB_00566 1.3e-154 pstA P phosphate transport system permease
PHGHKPIB_00567 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHGHKPIB_00568 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHGHKPIB_00569 7.1e-113 phoU P Plays a role in the regulation of phosphate uptake
PHGHKPIB_00570 0.0 pepN 3.4.11.2 E aminopeptidase
PHGHKPIB_00571 3.5e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
PHGHKPIB_00572 3.6e-185 lplA 6.3.1.20 H Lipoate-protein ligase
PHGHKPIB_00573 1.7e-37
PHGHKPIB_00574 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PHGHKPIB_00575 5.6e-299 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
PHGHKPIB_00576 2.1e-156 malR K Transcriptional regulator
PHGHKPIB_00577 3.9e-229 malX G ABC transporter
PHGHKPIB_00578 9.7e-250 malF P ABC transporter (Permease
PHGHKPIB_00579 9.8e-152 malG P ABC transporter (Permease
PHGHKPIB_00580 1.8e-212 msmX P Belongs to the ABC transporter superfamily
PHGHKPIB_00581 9.5e-23 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PHGHKPIB_00582 6e-118 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PHGHKPIB_00583 2.2e-288 ywbL P COG0672 High-affinity Fe2 Pb2 permease
PHGHKPIB_00584 1.4e-231 ycdB P peroxidase
PHGHKPIB_00585 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
PHGHKPIB_00586 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PHGHKPIB_00587 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
PHGHKPIB_00588 7.3e-20 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
PHGHKPIB_00589 0.0 3.5.1.28 NU amidase activity
PHGHKPIB_00590 0.0 lpdA 1.8.1.4 C Dehydrogenase
PHGHKPIB_00591 9.6e-213 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PHGHKPIB_00592 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PHGHKPIB_00593 5.6e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PHGHKPIB_00594 2.7e-206 hpk9 2.7.13.3 T protein histidine kinase activity
PHGHKPIB_00595 1.8e-224 2.7.13.3 T protein histidine kinase activity
PHGHKPIB_00596 3.3e-166 S the current gene model (or a revised gene model) may contain a frame shift
PHGHKPIB_00597 9.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PHGHKPIB_00598 1.2e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PHGHKPIB_00599 7.3e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PHGHKPIB_00600 2.2e-246 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PHGHKPIB_00601 8.2e-154 rssA S Phospholipase, patatin family
PHGHKPIB_00602 1.4e-102 estA E Lysophospholipase L1 and related esterases
PHGHKPIB_00603 1.8e-284 S unusual protein kinase
PHGHKPIB_00604 4.1e-38 S granule-associated protein
PHGHKPIB_00605 2.2e-284 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHGHKPIB_00606 8.8e-196 S hmm pf01594
PHGHKPIB_00607 9.9e-106 G Belongs to the phosphoglycerate mutase family
PHGHKPIB_00608 1.8e-107 G Belongs to the phosphoglycerate mutase family
PHGHKPIB_00609 4.8e-108 pgm G Belongs to the phosphoglycerate mutase family
PHGHKPIB_00610 6.2e-151 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PHGHKPIB_00612 4.8e-180 wbbI M transferase activity, transferring glycosyl groups
PHGHKPIB_00613 3.7e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
PHGHKPIB_00614 4.4e-245 epsU S Polysaccharide biosynthesis protein
PHGHKPIB_00615 2.2e-173
PHGHKPIB_00616 1.8e-152 M Glycosyltransferase like family 2
PHGHKPIB_00617 2.3e-128 M Glycosyltransferase, group 2 family protein
PHGHKPIB_00618 2.7e-117 Z012_10770 M Domain of unknown function (DUF1919)
PHGHKPIB_00619 5.1e-187 sacB GT2,GT4 M Stealth protein CR3, conserved region 3
PHGHKPIB_00620 5.4e-209 wcoF M Glycosyltransferase, group 1 family protein
PHGHKPIB_00621 4.3e-222 rgpAc GT4 M group 1 family protein
PHGHKPIB_00622 6.1e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PHGHKPIB_00623 3.4e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
PHGHKPIB_00624 7.7e-110 cps4C M biosynthesis protein
PHGHKPIB_00625 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
PHGHKPIB_00626 4.8e-247 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
PHGHKPIB_00627 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
PHGHKPIB_00628 5.1e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
PHGHKPIB_00629 2.8e-171 clcA_2 P Chloride transporter, ClC family
PHGHKPIB_00630 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PHGHKPIB_00631 4.2e-95 S Protein of unknown function (DUF1697)
PHGHKPIB_00632 8.7e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PHGHKPIB_00633 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PHGHKPIB_00634 8.1e-252 V Glucan-binding protein C
PHGHKPIB_00635 6.5e-227 V Glucan-binding protein C
PHGHKPIB_00636 1.6e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
PHGHKPIB_00637 2.9e-273 pepV 3.5.1.18 E Dipeptidase
PHGHKPIB_00638 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PHGHKPIB_00639 1.6e-91 yybC
PHGHKPIB_00640 2.5e-83 XK27_03610 K Gnat family
PHGHKPIB_00641 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PHGHKPIB_00642 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PHGHKPIB_00643 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PHGHKPIB_00644 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PHGHKPIB_00645 2.5e-17 M LysM domain
PHGHKPIB_00646 1.5e-86 ebsA S Family of unknown function (DUF5322)
PHGHKPIB_00647 3.3e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PHGHKPIB_00648 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PHGHKPIB_00649 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PHGHKPIB_00650 1.5e-220 G COG0457 FOG TPR repeat
PHGHKPIB_00651 3.6e-176 yubA S permease
PHGHKPIB_00652 3.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
PHGHKPIB_00653 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PHGHKPIB_00654 3.2e-124 ftsE D cell division ATP-binding protein FtsE
PHGHKPIB_00655 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PHGHKPIB_00656 3.2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PHGHKPIB_00657 1.4e-158 yjjH S Calcineurin-like phosphoesterase
PHGHKPIB_00658 1.3e-131 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PHGHKPIB_00659 0.0 pacL 3.6.3.8 P cation transport ATPase
PHGHKPIB_00660 1.5e-67 ywiB S Domain of unknown function (DUF1934)
PHGHKPIB_00661 2.9e-146 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
PHGHKPIB_00662 4.6e-146 yidA S hydrolases of the HAD superfamily
PHGHKPIB_00663 1.3e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
PHGHKPIB_00664 1e-57 S Protein of unknown function (DUF454)
PHGHKPIB_00665 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
PHGHKPIB_00666 3.2e-220 vicK 2.7.13.3 T Histidine kinase
PHGHKPIB_00667 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PHGHKPIB_00668 1.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
PHGHKPIB_00669 1.4e-145 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PHGHKPIB_00670 1.9e-116 gltJ P ABC transporter (Permease
PHGHKPIB_00671 1.9e-116 gltJ P ABC transporter (Permease
PHGHKPIB_00672 1.4e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PHGHKPIB_00673 6.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
PHGHKPIB_00674 3.7e-16 tcyB_2 P ABC transporter (permease)
PHGHKPIB_00676 1.9e-07
PHGHKPIB_00681 2.8e-194 L Phage integrase family
PHGHKPIB_00682 3.5e-28 S Domain of unknown function (DUF3173)
PHGHKPIB_00683 3.4e-67
PHGHKPIB_00684 1.1e-225 J Replication initiation factor
PHGHKPIB_00685 2.5e-75
PHGHKPIB_00686 9.6e-77 K transcriptional
PHGHKPIB_00687 1.5e-218
PHGHKPIB_00688 6.8e-125 V ABC transporter
PHGHKPIB_00689 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHGHKPIB_00690 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PHGHKPIB_00691 1.2e-35 XK27_02060 S Transglycosylase associated protein
PHGHKPIB_00692 3.9e-72 badR K Transcriptional regulator, marr family
PHGHKPIB_00693 3.6e-94 S reductase
PHGHKPIB_00695 1.3e-287 ahpF O alkyl hydroperoxide reductase
PHGHKPIB_00696 2.4e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
PHGHKPIB_00697 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
PHGHKPIB_00698 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PHGHKPIB_00699 1.6e-82 S Putative small multi-drug export protein
PHGHKPIB_00700 2e-74 ctsR K Belongs to the CtsR family
PHGHKPIB_00701 0.0 clpC O Belongs to the ClpA ClpB family
PHGHKPIB_00702 7.9e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PHGHKPIB_00703 2e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PHGHKPIB_00704 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PHGHKPIB_00705 4.7e-140 S SseB protein N-terminal domain
PHGHKPIB_00706 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
PHGHKPIB_00708 4e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PHGHKPIB_00709 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PHGHKPIB_00711 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHGHKPIB_00712 1.3e-90 yacP S RNA-binding protein containing a PIN domain
PHGHKPIB_00713 1.3e-151 degV S DegV family
PHGHKPIB_00715 5.1e-22 K Transcriptional
PHGHKPIB_00716 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PHGHKPIB_00717 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
PHGHKPIB_00718 3.4e-222 int2 L Phage integrase family
PHGHKPIB_00719 1.1e-40 S Helix-turn-helix domain
PHGHKPIB_00720 2.5e-189 L Replication initiation factor
PHGHKPIB_00721 5.3e-37
PHGHKPIB_00723 3.7e-81 K DNA-binding helix-turn-helix protein
PHGHKPIB_00724 9.3e-28 pepE 3.4.13.21 E Belongs to the peptidase S51 family
PHGHKPIB_00725 7.1e-272 Q synthase
PHGHKPIB_00726 1.5e-185 bioF 2.3.1.29, 2.3.1.47, 2.3.1.50 E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PHGHKPIB_00727 7.7e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHGHKPIB_00728 1.9e-103 wecD M Acetyltransferase (GNAT) domain
PHGHKPIB_00729 1.1e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PHGHKPIB_00730 2e-158 GK ROK family
PHGHKPIB_00731 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
PHGHKPIB_00732 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
PHGHKPIB_00733 2.6e-205 potD P spermidine putrescine ABC transporter
PHGHKPIB_00734 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
PHGHKPIB_00735 5.3e-139 potB P ABC-type spermidine putrescine transport system, permease component I
PHGHKPIB_00736 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PHGHKPIB_00737 3.1e-167 murB 1.3.1.98 M cell wall formation
PHGHKPIB_00738 8.2e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PHGHKPIB_00739 1.3e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PHGHKPIB_00740 1.4e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
PHGHKPIB_00741 7.7e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PHGHKPIB_00742 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
PHGHKPIB_00743 0.0 ydaO E amino acid
PHGHKPIB_00744 4.9e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PHGHKPIB_00745 1.5e-36 ylqC L Belongs to the UPF0109 family
PHGHKPIB_00746 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PHGHKPIB_00748 4.8e-201 2.7.13.3 T protein histidine kinase activity
PHGHKPIB_00749 2.6e-124 agrA KT phosphorelay signal transduction system
PHGHKPIB_00750 1.5e-170 O protein import
PHGHKPIB_00751 1.3e-165 tehB 2.1.1.265 PQ tellurite resistance protein tehb
PHGHKPIB_00752 8.3e-17 yjdB S Domain of unknown function (DUF4767)
PHGHKPIB_00753 9.5e-64 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PHGHKPIB_00755 9.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
PHGHKPIB_00756 4.9e-71 S QueT transporter
PHGHKPIB_00758 1.2e-169 yfjR K regulation of single-species biofilm formation
PHGHKPIB_00760 2.4e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PHGHKPIB_00761 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PHGHKPIB_00762 3.7e-85 ccl S cog cog4708
PHGHKPIB_00763 8.4e-160 rbn E Belongs to the UPF0761 family
PHGHKPIB_00764 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
PHGHKPIB_00765 1.9e-231 ytoI K transcriptional regulator containing CBS domains
PHGHKPIB_00766 1.2e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
PHGHKPIB_00767 1.5e-228 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHGHKPIB_00768 0.0 comEC S Competence protein ComEC
PHGHKPIB_00769 3.7e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PHGHKPIB_00770 1.7e-142 plsC 2.3.1.51 I Acyltransferase
PHGHKPIB_00771 4.5e-137 nodB3 G deacetylase
PHGHKPIB_00772 3.3e-138 yabB 2.1.1.223 L Methyltransferase
PHGHKPIB_00773 1.9e-40 yazA L endonuclease containing a URI domain
PHGHKPIB_00774 0.0 S dextransucrase activity
PHGHKPIB_00775 5.8e-30 liaI KT membrane
PHGHKPIB_00776 7e-15 liaI KT membrane
PHGHKPIB_00777 2e-155 XK27_09825 V abc transporter atp-binding protein
PHGHKPIB_00778 3.5e-08
PHGHKPIB_00779 5.7e-190 XK27_10075 S abc transporter atp-binding protein
PHGHKPIB_00780 0.0 V abc transporter atp-binding protein
PHGHKPIB_00781 2.7e-297 V abc transporter atp-binding protein
PHGHKPIB_00782 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
PHGHKPIB_00784 6.1e-285 S Protein of unknown function (DUF3114)
PHGHKPIB_00785 1e-96 2.3.1.128 K Acetyltransferase GNAT Family
PHGHKPIB_00786 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PHGHKPIB_00787 2.7e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
PHGHKPIB_00788 1.7e-186 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
PHGHKPIB_00789 2.2e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PHGHKPIB_00790 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PHGHKPIB_00791 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PHGHKPIB_00792 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PHGHKPIB_00793 1.6e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PHGHKPIB_00794 7.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PHGHKPIB_00795 9.9e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PHGHKPIB_00798 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PHGHKPIB_00799 3.9e-171 vraS 2.7.13.3 T Histidine kinase
PHGHKPIB_00800 3.3e-116 yvqF S Membrane
PHGHKPIB_00801 1.5e-103 kcsA P Ion transport protein
PHGHKPIB_00802 2.3e-294 prkC 2.7.11.1 KLT serine threonine protein kinase
PHGHKPIB_00803 1.5e-135 stp 3.1.3.16 T phosphatase
PHGHKPIB_00804 1.5e-170 M Psort location CytoplasmicMembrane, score
PHGHKPIB_00805 8.7e-229 GT4 M transferase activity, transferring glycosyl groups
PHGHKPIB_00806 2.9e-09 S CsbD-like
PHGHKPIB_00807 5.5e-31 S Membrane
PHGHKPIB_00808 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
PHGHKPIB_00809 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PHGHKPIB_00810 1.2e-228 cinA 3.5.1.42 S Belongs to the CinA family
PHGHKPIB_00811 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
PHGHKPIB_00812 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PHGHKPIB_00814 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PHGHKPIB_00816 1.1e-69 K LytTr DNA-binding domain
PHGHKPIB_00817 1.5e-77 S Protein of unknown function (DUF3021)
PHGHKPIB_00818 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PHGHKPIB_00819 2.5e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PHGHKPIB_00820 3.1e-69 argR K Regulates arginine biosynthesis genes
PHGHKPIB_00821 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PHGHKPIB_00822 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PHGHKPIB_00823 3.6e-71 S KAP family P-loop domain
PHGHKPIB_00824 1.9e-15 S NYN domain
PHGHKPIB_00825 1.1e-200 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PHGHKPIB_00826 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PHGHKPIB_00827 2.3e-237 purD 6.3.4.13 F Belongs to the GARS family
PHGHKPIB_00828 1.9e-158 S CHAP domain
PHGHKPIB_00829 4.2e-35 L reverse transcriptase
PHGHKPIB_00830 1.5e-291 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PHGHKPIB_00831 1.2e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PHGHKPIB_00832 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PHGHKPIB_00833 7.8e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PHGHKPIB_00834 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHGHKPIB_00835 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PHGHKPIB_00836 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHGHKPIB_00837 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PHGHKPIB_00838 8e-140 recO L Involved in DNA repair and RecF pathway recombination
PHGHKPIB_00839 2.5e-217 araT 2.6.1.1 E Aminotransferase
PHGHKPIB_00840 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHGHKPIB_00841 2.1e-83 usp 3.5.1.28 CBM50 S CHAP domain
PHGHKPIB_00842 1.1e-81 mreD M rod shape-determining protein MreD
PHGHKPIB_00843 3.2e-94 mreC M Involved in formation and maintenance of cell shape
PHGHKPIB_00848 3.8e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
PHGHKPIB_00849 3.1e-270 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PHGHKPIB_00850 1.5e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
PHGHKPIB_00851 2.2e-99 yvdD 3.2.2.10 S Belongs to the LOG family
PHGHKPIB_00852 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PHGHKPIB_00853 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PHGHKPIB_00854 8e-42 ylxQ J ribosomal protein
PHGHKPIB_00855 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
PHGHKPIB_00856 1.6e-195 nusA K Participates in both transcription termination and antitermination
PHGHKPIB_00857 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
PHGHKPIB_00858 4.4e-188 brpA K Transcriptional
PHGHKPIB_00859 1.1e-87 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
PHGHKPIB_00860 1e-75 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
PHGHKPIB_00861 1.6e-247 pbuO S permease
PHGHKPIB_00862 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
PHGHKPIB_00863 3e-136 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
PHGHKPIB_00864 1.4e-168 manL 2.7.1.191 G pts system
PHGHKPIB_00865 3.4e-133 manY G pts system
PHGHKPIB_00866 3.8e-157 manN G PTS system mannose fructose sorbose family IID component
PHGHKPIB_00867 2.2e-66 manO S Protein conserved in bacteria
PHGHKPIB_00868 4.9e-174 manL 2.7.1.191 G pts system
PHGHKPIB_00869 1.3e-116 manM G pts system
PHGHKPIB_00870 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
PHGHKPIB_00871 1.9e-62 manO S protein conserved in bacteria
PHGHKPIB_00872 6.2e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PHGHKPIB_00873 8.8e-113
PHGHKPIB_00874 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PHGHKPIB_00875 4.4e-166 dnaI L Primosomal protein DnaI
PHGHKPIB_00876 4.4e-214 dnaB L Replication initiation and membrane attachment
PHGHKPIB_00877 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PHGHKPIB_00878 5.9e-280 T PhoQ Sensor
PHGHKPIB_00879 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PHGHKPIB_00880 6.2e-91 yceD K metal-binding, possibly nucleic acid-binding protein
PHGHKPIB_00881 4.9e-128 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
PHGHKPIB_00882 2.1e-236 P COG0168 Trk-type K transport systems, membrane components
PHGHKPIB_00883 8e-120 ktrA P COG0569 K transport systems, NAD-binding component
PHGHKPIB_00884 4.5e-149 cbiQ P cobalt transport
PHGHKPIB_00885 1.2e-310 ykoD P abc transporter atp-binding protein
PHGHKPIB_00886 3e-93 S UPF0397 protein
PHGHKPIB_00887 4.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
PHGHKPIB_00888 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PHGHKPIB_00889 8e-99 metI P ABC transporter (Permease
PHGHKPIB_00890 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHGHKPIB_00891 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
PHGHKPIB_00892 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
PHGHKPIB_00893 6.3e-138 ET ABC transporter substrate-binding protein
PHGHKPIB_00894 6.3e-131 cbiO P ABC transporter
PHGHKPIB_00895 2.9e-137 P cobalt transport protein
PHGHKPIB_00896 2.1e-177 cbiM P PDGLE domain
PHGHKPIB_00897 6.4e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PHGHKPIB_00898 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PHGHKPIB_00899 1.7e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PHGHKPIB_00900 6.6e-78 ureE O enzyme active site formation
PHGHKPIB_00901 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PHGHKPIB_00902 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PHGHKPIB_00903 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PHGHKPIB_00904 6.8e-95 ureI S AmiS/UreI family transporter
PHGHKPIB_00905 1.7e-241 S Domain of unknown function (DUF4173)
PHGHKPIB_00906 3.2e-53 yhaI L Membrane
PHGHKPIB_00907 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PHGHKPIB_00908 1.3e-138 K sequence-specific DNA binding
PHGHKPIB_00909 1.3e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
PHGHKPIB_00910 3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PHGHKPIB_00911 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PHGHKPIB_00912 7.2e-245 trkA P Potassium transporter peripheral membrane component
PHGHKPIB_00913 7.9e-258 trkH P Cation transport protein
PHGHKPIB_00914 4.4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PHGHKPIB_00915 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PHGHKPIB_00916 2.6e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PHGHKPIB_00917 3.4e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PHGHKPIB_00918 1.8e-131 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
PHGHKPIB_00919 8.3e-87 ykuL S CBS domain
PHGHKPIB_00920 5.1e-98 XK27_09740 S Phosphoesterase
PHGHKPIB_00921 3.6e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PHGHKPIB_00922 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PHGHKPIB_00923 1.6e-36 yneF S UPF0154 protein
PHGHKPIB_00924 1.8e-90 K transcriptional regulator
PHGHKPIB_00925 3.6e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PHGHKPIB_00926 1.9e-12 ycdA S Domain of unknown function (DUF4352)
PHGHKPIB_00927 2.2e-101 ybhL S Belongs to the BI1 family
PHGHKPIB_00928 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
PHGHKPIB_00929 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHGHKPIB_00930 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PHGHKPIB_00931 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHGHKPIB_00932 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHGHKPIB_00933 7.1e-302 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PHGHKPIB_00934 1.5e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
PHGHKPIB_00935 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PHGHKPIB_00936 9.6e-23
PHGHKPIB_00937 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
PHGHKPIB_00938 2.2e-282 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
PHGHKPIB_00939 7.4e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PHGHKPIB_00940 2.1e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PHGHKPIB_00941 5.8e-94 ypsA S Belongs to the UPF0398 family
PHGHKPIB_00942 9.6e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PHGHKPIB_00943 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PHGHKPIB_00944 5.8e-255 pepC 3.4.22.40 E aminopeptidase
PHGHKPIB_00945 2.6e-71 yhaI S Protein of unknown function (DUF805)
PHGHKPIB_00946 4.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PHGHKPIB_00947 2.8e-271 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHGHKPIB_00948 3.3e-215 macB_2 V FtsX-like permease family
PHGHKPIB_00949 2.5e-121 yhcA V abc transporter atp-binding protein
PHGHKPIB_00950 1.3e-123 mta K Transcriptional
PHGHKPIB_00951 2.3e-32 S Protein of unknown function (DUF3021)
PHGHKPIB_00952 5.8e-74 K COG3279 Response regulator of the LytR AlgR family
PHGHKPIB_00953 4.6e-133 cylB V ABC-2 type transporter
PHGHKPIB_00954 2.4e-153 cylA V abc transporter atp-binding protein
PHGHKPIB_00955 1.5e-52 K regulation of RNA biosynthetic process
PHGHKPIB_00956 2.2e-45 3.2.2.21 S YCII-related domain
PHGHKPIB_00957 7.5e-36 yjdF S Protein of unknown function (DUF2992)
PHGHKPIB_00958 1.9e-220 S COG1073 Hydrolases of the alpha beta superfamily
PHGHKPIB_00959 3.8e-73 K helix_turn_helix multiple antibiotic resistance protein
PHGHKPIB_00960 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PHGHKPIB_00961 6.5e-134 glcR K transcriptional regulator (DeoR family)
PHGHKPIB_00962 8.1e-143 cof S Sucrose-6F-phosphate phosphohydrolase
PHGHKPIB_00963 4.9e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
PHGHKPIB_00964 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
PHGHKPIB_00965 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
PHGHKPIB_00966 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PHGHKPIB_00967 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PHGHKPIB_00968 8.9e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PHGHKPIB_00969 1.7e-54 S TM2 domain
PHGHKPIB_00970 5e-45
PHGHKPIB_00972 8.2e-288 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PHGHKPIB_00973 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PHGHKPIB_00974 4e-142 cmpC S abc transporter atp-binding protein
PHGHKPIB_00975 0.0 WQ51_06230 S ABC transporter
PHGHKPIB_00976 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PHGHKPIB_00977 2.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PHGHKPIB_00978 2.8e-132 cdsA 2.7.7.41 S Belongs to the CDS family
PHGHKPIB_00979 2e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PHGHKPIB_00980 5.9e-47 yajC U protein transport
PHGHKPIB_00981 6.1e-126 yeeN K transcriptional regulatory protein
PHGHKPIB_00982 8.9e-279 V ABC transporter
PHGHKPIB_00983 3.5e-152 Z012_04635 K sequence-specific DNA binding
PHGHKPIB_00984 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
PHGHKPIB_00985 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
PHGHKPIB_00986 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PHGHKPIB_00987 5.3e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PHGHKPIB_00988 9.6e-128 adcB P ABC transporter (Permease
PHGHKPIB_00989 9.2e-135 adcC P ABC transporter, ATP-binding protein
PHGHKPIB_00990 5.9e-71 adcR K transcriptional
PHGHKPIB_00991 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHGHKPIB_00992 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PHGHKPIB_00993 2.1e-26
PHGHKPIB_00994 2.9e-273 sufB O assembly protein SufB
PHGHKPIB_00995 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
PHGHKPIB_00996 1.1e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PHGHKPIB_00997 2e-233 sufD O assembly protein SufD
PHGHKPIB_00998 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PHGHKPIB_00999 8.7e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
PHGHKPIB_01000 1.6e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PHGHKPIB_01001 2.4e-17 S Protein of unknown function (DUF3021)
PHGHKPIB_01002 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PHGHKPIB_01003 1.8e-271 glnP P ABC transporter
PHGHKPIB_01004 2.2e-123 glnQ E abc transporter atp-binding protein
PHGHKPIB_01005 2.1e-184 D nuclear chromosome segregation
PHGHKPIB_01006 1.6e-84 V VanZ like family
PHGHKPIB_01007 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PHGHKPIB_01008 3.3e-190 yhjX P Major Facilitator
PHGHKPIB_01009 3.4e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PHGHKPIB_01010 2.1e-111 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PHGHKPIB_01011 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PHGHKPIB_01012 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PHGHKPIB_01013 8.2e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PHGHKPIB_01014 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHGHKPIB_01015 1.2e-82 nrdI F Belongs to the NrdI family
PHGHKPIB_01016 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PHGHKPIB_01017 1.1e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PHGHKPIB_01018 7.7e-177 prmA J Ribosomal protein L11 methyltransferase
PHGHKPIB_01019 4.9e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
PHGHKPIB_01020 1.6e-82 XK27_03960 S Protein of unknown function (DUF3013)
PHGHKPIB_01021 1.1e-308 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PHGHKPIB_01022 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PHGHKPIB_01023 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PHGHKPIB_01024 4e-139 ykuT M mechanosensitive ion channel
PHGHKPIB_01025 3.9e-87 sigH K DNA-templated transcription, initiation
PHGHKPIB_01027 3.3e-186 nss M transferase activity, transferring glycosyl groups
PHGHKPIB_01028 3.6e-16 S Accessory secretory protein Sec, Asp5
PHGHKPIB_01029 2.6e-17 S Accessory secretory protein Sec Asp4
PHGHKPIB_01030 3e-243 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PHGHKPIB_01031 9.7e-283 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PHGHKPIB_01032 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHGHKPIB_01033 1e-78 asp3 S Accessory Sec system protein Asp3
PHGHKPIB_01034 2e-288 asp2 3.4.11.5 S Accessory Sec system protein Asp2
PHGHKPIB_01035 5e-290 asp1 S Accessory Sec system protein Asp1
PHGHKPIB_01036 3.6e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
PHGHKPIB_01037 0.0 M family 8
PHGHKPIB_01038 0.0 sbcC L ATPase involved in DNA repair
PHGHKPIB_01039 6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PHGHKPIB_01040 0.0 GM domain, Protein
PHGHKPIB_01041 0.0 zmpB M signal peptide protein, YSIRK family
PHGHKPIB_01042 0.0 M domain protein
PHGHKPIB_01043 9.5e-173 pdhD 1.8.1.4 C Dehydrogenase
PHGHKPIB_01044 3.6e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
PHGHKPIB_01045 1.3e-174 acoB C dehydrogenase E1 component
PHGHKPIB_01046 7.9e-142 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PHGHKPIB_01047 4.6e-79 Q Methyltransferase domain
PHGHKPIB_01048 8.9e-75 K TetR family transcriptional regulator
PHGHKPIB_01049 3.5e-46
PHGHKPIB_01050 1.6e-129 V CAAX protease self-immunity
PHGHKPIB_01051 5.8e-10
PHGHKPIB_01052 6.5e-19 S Bacterial lipoprotein
PHGHKPIB_01053 8.3e-61 S Protein of unknown function (DUF1722)
PHGHKPIB_01054 6.3e-63 yqeB S Pyrimidine dimer DNA glycosylase
PHGHKPIB_01056 2.7e-50
PHGHKPIB_01057 7.6e-112 estA E GDSL-like Lipase/Acylhydrolase
PHGHKPIB_01058 6.4e-100
PHGHKPIB_01059 8.7e-277 sulP P Sulfate permease and related transporters (MFS superfamily)
PHGHKPIB_01060 8.4e-148 ycgQ S TIGR03943 family
PHGHKPIB_01061 1e-154 XK27_03015 S permease
PHGHKPIB_01063 0.0 yhgF K Transcriptional accessory protein
PHGHKPIB_01064 2.2e-41 pspC KT PspC domain
PHGHKPIB_01065 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PHGHKPIB_01066 5.8e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PHGHKPIB_01067 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PHGHKPIB_01068 6.7e-67 ytxH S General stress protein
PHGHKPIB_01070 1.5e-177 yegQ O Peptidase U32
PHGHKPIB_01071 1.9e-250 yegQ O Peptidase U32
PHGHKPIB_01072 1.1e-87 bioY S biotin synthase
PHGHKPIB_01074 1.1e-33 XK27_12190 S protein conserved in bacteria
PHGHKPIB_01075 6.2e-233 mntH P H( )-stimulated, divalent metal cation uptake system
PHGHKPIB_01076 1.7e-11
PHGHKPIB_01077 2.2e-14
PHGHKPIB_01078 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PHGHKPIB_01079 2.2e-137 M LysM domain
PHGHKPIB_01080 3.8e-23
PHGHKPIB_01081 5.8e-174 S hydrolase
PHGHKPIB_01083 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
PHGHKPIB_01084 3e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PHGHKPIB_01085 3.5e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
PHGHKPIB_01086 1.3e-26 P Hemerythrin HHE cation binding domain protein
PHGHKPIB_01087 5.4e-158 5.2.1.8 G hydrolase
PHGHKPIB_01088 1.2e-239 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PHGHKPIB_01089 4.9e-111 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PHGHKPIB_01090 5.9e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PHGHKPIB_01091 1.9e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PHGHKPIB_01092 1.5e-65 GnaT 2.5.1.16 K acetyltransferase
PHGHKPIB_01093 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
PHGHKPIB_01094 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PHGHKPIB_01095 1.1e-180 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PHGHKPIB_01096 6.5e-125 dnaD
PHGHKPIB_01097 3.8e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PHGHKPIB_01099 5.1e-235 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHGHKPIB_01100 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHGHKPIB_01101 2.2e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PHGHKPIB_01102 1.1e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PHGHKPIB_01103 3.7e-73 argR K Regulates arginine biosynthesis genes
PHGHKPIB_01104 1.3e-299 recN L May be involved in recombinational repair of damaged DNA
PHGHKPIB_01105 6.6e-148 DegV S DegV family
PHGHKPIB_01106 1.1e-158 ypmR E COG2755 Lysophospholipase L1 and related esterases
PHGHKPIB_01107 5.2e-96 ypmS S Protein conserved in bacteria
PHGHKPIB_01108 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PHGHKPIB_01110 3.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
PHGHKPIB_01111 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHGHKPIB_01112 2.1e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PHGHKPIB_01113 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PHGHKPIB_01114 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PHGHKPIB_01115 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PHGHKPIB_01116 0.0 dnaE 2.7.7.7 L DNA polymerase
PHGHKPIB_01117 1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PHGHKPIB_01118 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PHGHKPIB_01119 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PHGHKPIB_01120 3.5e-280 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
PHGHKPIB_01121 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
PHGHKPIB_01122 2.3e-224 vncS 2.7.13.3 T Histidine kinase
PHGHKPIB_01123 1.5e-115 K Response regulator receiver domain protein
PHGHKPIB_01124 1.6e-239 vex3 V Efflux ABC transporter, permease protein
PHGHKPIB_01125 6.6e-108 vex2 V abc transporter atp-binding protein
PHGHKPIB_01126 7.8e-177 vex1 V Efflux ABC transporter, permease protein
PHGHKPIB_01127 1.9e-283 XK27_07020 S Belongs to the UPF0371 family
PHGHKPIB_01129 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
PHGHKPIB_01130 1e-176 XK27_10475 S oxidoreductase
PHGHKPIB_01131 4.8e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
PHGHKPIB_01132 3.2e-93 dhaL 2.7.1.121 S Dihydroxyacetone kinase
PHGHKPIB_01133 1.2e-177 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
PHGHKPIB_01134 8.2e-227 thrE K Psort location CytoplasmicMembrane, score
PHGHKPIB_01135 3.2e-34 S Immunity protein 41
PHGHKPIB_01136 0.0 pepO 3.4.24.71 O Peptidase family M13
PHGHKPIB_01137 2.4e-08 S Enterocin A Immunity
PHGHKPIB_01138 1.1e-192 mccF V LD-carboxypeptidase
PHGHKPIB_01139 1.2e-15 S integral membrane protein
PHGHKPIB_01140 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
PHGHKPIB_01141 1.7e-107 yhfC S Putative membrane peptidase family (DUF2324)
PHGHKPIB_01143 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PHGHKPIB_01145 2.4e-241 S dextransucrase activity
PHGHKPIB_01146 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PHGHKPIB_01147 1.6e-302 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PHGHKPIB_01148 1.9e-88 L COG1943 Transposase and inactivated derivatives
PHGHKPIB_01149 1.7e-258 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PHGHKPIB_01150 8.7e-154 corA P CorA-like protein
PHGHKPIB_01151 3.3e-62 yjqA S Bacterial PH domain
PHGHKPIB_01152 1.7e-99 thiT S Thiamine transporter
PHGHKPIB_01153 7.8e-152 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PHGHKPIB_01154 1.9e-193 yjbB G Permeases of the major facilitator superfamily
PHGHKPIB_01155 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PHGHKPIB_01156 2.2e-114 ywaF S Integral membrane protein (intg_mem_TP0381)
PHGHKPIB_01157 5e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PHGHKPIB_01161 1.7e-154 cjaA ET ABC transporter substrate-binding protein
PHGHKPIB_01162 2.2e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
PHGHKPIB_01163 3e-106 P ABC transporter (Permease
PHGHKPIB_01164 3e-114 papP P ABC transporter (Permease
PHGHKPIB_01165 6e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PHGHKPIB_01166 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
PHGHKPIB_01167 0.0 copA 3.6.3.54 P P-type ATPase
PHGHKPIB_01168 5.2e-72 copY K negative regulation of transcription, DNA-templated
PHGHKPIB_01169 2.8e-173 EGP Major facilitator Superfamily
PHGHKPIB_01170 7.8e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PHGHKPIB_01171 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PHGHKPIB_01172 1e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
PHGHKPIB_01173 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PHGHKPIB_01174 3.9e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PHGHKPIB_01175 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
PHGHKPIB_01176 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PHGHKPIB_01177 4.4e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
PHGHKPIB_01178 2e-58
PHGHKPIB_01179 0.0 ctpE P E1-E2 ATPase
PHGHKPIB_01180 5.4e-43
PHGHKPIB_01181 4.7e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PHGHKPIB_01182 2.7e-59 XK27_08085
PHGHKPIB_01183 1.6e-191 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PHGHKPIB_01184 1.4e-181 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PHGHKPIB_01185 8e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PHGHKPIB_01186 4.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PHGHKPIB_01187 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PHGHKPIB_01188 2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PHGHKPIB_01189 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PHGHKPIB_01190 4.7e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PHGHKPIB_01191 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PHGHKPIB_01192 1.2e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PHGHKPIB_01194 6.5e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
PHGHKPIB_01195 9.2e-144 P molecular chaperone
PHGHKPIB_01196 2.8e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
PHGHKPIB_01197 4.7e-180 XK27_08075 M glycosyl transferase family 2
PHGHKPIB_01198 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PHGHKPIB_01199 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PHGHKPIB_01200 1.7e-100 L COG3547 Transposase and inactivated derivatives
PHGHKPIB_01201 4.1e-57 L transposase IS116 IS110 IS902 family
PHGHKPIB_01202 1.5e-14 L COG3547 Transposase and inactivated derivatives
PHGHKPIB_01203 2e-42 mccF V LD-carboxypeptidase
PHGHKPIB_01204 8.5e-163 L High confidence in function and specificity
PHGHKPIB_01205 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PHGHKPIB_01206 1.1e-23
PHGHKPIB_01207 3.8e-214 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHGHKPIB_01208 1.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
PHGHKPIB_01209 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
PHGHKPIB_01210 4.5e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
PHGHKPIB_01211 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PHGHKPIB_01212 2.1e-64 S Domain of unknown function (DUF4430)
PHGHKPIB_01213 2.1e-74 S Psort location CytoplasmicMembrane, score
PHGHKPIB_01214 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
PHGHKPIB_01215 5.6e-131 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
PHGHKPIB_01216 3.3e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
PHGHKPIB_01217 9.1e-113 sirR K iron dependent repressor
PHGHKPIB_01218 3.4e-134 htpX O Belongs to the peptidase M48B family
PHGHKPIB_01219 7.7e-92 lemA S LemA family
PHGHKPIB_01220 2.9e-174 spd F DNA RNA non-specific endonuclease
PHGHKPIB_01221 0.0 2.4.1.21 GT5 M Right handed beta helix region
PHGHKPIB_01222 4e-151 S double-stranded DNA endodeoxyribonuclease activity
PHGHKPIB_01223 2.7e-194 higA K Pfam:DUF955
PHGHKPIB_01224 2.3e-51
PHGHKPIB_01225 1.1e-90
PHGHKPIB_01226 2.3e-06 S Domain of unknown function (DUF4868)
PHGHKPIB_01227 9.3e-98 3.1.21.3 L Type I restriction modification DNA specificity domain
PHGHKPIB_01228 8.2e-272 hsdM 2.1.1.72 V N-6 DNA Methylase
PHGHKPIB_01229 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
PHGHKPIB_01231 3.8e-134 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PHGHKPIB_01232 1.9e-209 MA20_36090 S Protein of unknown function (DUF2974)
PHGHKPIB_01233 1.5e-112 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PHGHKPIB_01234 9e-60
PHGHKPIB_01235 1.5e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
PHGHKPIB_01236 1.1e-148 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PHGHKPIB_01237 1.4e-98 yqeG S hydrolase of the HAD superfamily
PHGHKPIB_01238 5.4e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PHGHKPIB_01239 7.7e-49 yhbY J RNA-binding protein
PHGHKPIB_01240 1.7e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PHGHKPIB_01241 6.4e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PHGHKPIB_01242 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PHGHKPIB_01243 1.9e-138 yqeM Q Methyltransferase domain protein
PHGHKPIB_01244 1.2e-197 ylbM S Belongs to the UPF0348 family
PHGHKPIB_01245 1.7e-38 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PHGHKPIB_01246 1e-43 yoeB S Addiction module toxin, Txe YoeB family
PHGHKPIB_01247 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
PHGHKPIB_01250 4.1e-07
PHGHKPIB_01251 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PHGHKPIB_01252 3.7e-131 ecsA V abc transporter atp-binding protein
PHGHKPIB_01253 1e-174 ecsB U Bacterial ABC transporter protein EcsB
PHGHKPIB_01254 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
PHGHKPIB_01255 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PHGHKPIB_01257 6.3e-221 ytfP S Flavoprotein
PHGHKPIB_01258 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PHGHKPIB_01259 2.8e-63 XK27_02560 S cog cog2151
PHGHKPIB_01260 2.6e-41 WQ51_02910 S Protein of unknown function, DUF536
PHGHKPIB_01261 6.4e-105 dnaQ 2.7.7.7 L DNA polymerase III
PHGHKPIB_01262 3.1e-125 K transcriptional regulator, MerR family
PHGHKPIB_01263 0.0 V ABC transporter (Permease
PHGHKPIB_01264 3.9e-125 V abc transporter atp-binding protein
PHGHKPIB_01266 3.9e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PHGHKPIB_01267 9e-47
PHGHKPIB_01268 1.5e-169 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PHGHKPIB_01269 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PHGHKPIB_01270 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
PHGHKPIB_01271 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PHGHKPIB_01272 7e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PHGHKPIB_01273 3.5e-146 XK27_02985 S overlaps another CDS with the same product name
PHGHKPIB_01274 2.6e-146 supH S overlaps another CDS with the same product name
PHGHKPIB_01275 5.6e-62 yvoA_1 K Transcriptional
PHGHKPIB_01276 4.1e-119 skfE V abc transporter atp-binding protein
PHGHKPIB_01277 4.5e-130 V Psort location CytoplasmicMembrane, score
PHGHKPIB_01278 4.7e-171 oppF P Belongs to the ABC transporter superfamily
PHGHKPIB_01279 3.9e-201 oppD P Belongs to the ABC transporter superfamily
PHGHKPIB_01280 3.8e-165 amiD P ABC transporter (Permease
PHGHKPIB_01281 1.1e-275 amiC P ABC transporter (Permease
PHGHKPIB_01282 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
PHGHKPIB_01283 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PHGHKPIB_01284 4.7e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PHGHKPIB_01285 2.7e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PHGHKPIB_01286 1.3e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PHGHKPIB_01287 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
PHGHKPIB_01288 2.4e-101 yjbK S Adenylate cyclase
PHGHKPIB_01289 8.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHGHKPIB_01290 4.3e-203 iscS 2.8.1.7 E Cysteine desulfurase
PHGHKPIB_01291 8.2e-60 XK27_04120 S Putative amino acid metabolism
PHGHKPIB_01292 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PHGHKPIB_01293 1.5e-129 puuD T peptidase C26
PHGHKPIB_01294 3.1e-111 radC E Belongs to the UPF0758 family
PHGHKPIB_01295 8.6e-22
PHGHKPIB_01296 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PHGHKPIB_01297 0.0 3.5.1.28 M domain protein
PHGHKPIB_01298 1.2e-135 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
PHGHKPIB_01299 2.3e-88 V abc transporter atp-binding protein
PHGHKPIB_01300 3.4e-16
PHGHKPIB_01302 2.5e-73 K Transcriptional regulatory protein, C terminal
PHGHKPIB_01303 2.2e-63 2.7.13.3 T Histidine kinase
PHGHKPIB_01304 2.7e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
PHGHKPIB_01305 4e-66 rmaI K Transcriptional regulator, MarR family
PHGHKPIB_01306 1.3e-236 EGP Major facilitator Superfamily
PHGHKPIB_01307 6e-132 XK27_00785 S CAAX protease self-immunity
PHGHKPIB_01308 1.4e-119 mleR K malolactic fermentation system
PHGHKPIB_01309 1.2e-47 K Helix-turn-helix
PHGHKPIB_01310 9.3e-308 sfcA 1.1.1.38, 4.1.1.101 C malic enzyme
PHGHKPIB_01311 1.1e-162 mleP S auxin efflux carrier
PHGHKPIB_01312 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHGHKPIB_01314 6.8e-142 rgpC GM Transport permease protein
PHGHKPIB_01315 2.4e-175 rgpB GT2 M Glycosyltransferase, group 2 family protein
PHGHKPIB_01316 3.2e-227 rodA D Belongs to the SEDS family
PHGHKPIB_01317 8.6e-18 S dextransucrase activity
PHGHKPIB_01318 6.7e-109
PHGHKPIB_01319 9.1e-152 2.4.1.60 S Glycosyltransferase group 2 family protein
PHGHKPIB_01320 3.2e-43 S Uncharacterized conserved protein (DUF2304)
PHGHKPIB_01321 3.5e-126 arnC M group 2 family protein
PHGHKPIB_01322 4.4e-180 cpsIaJ S Glycosyltransferase like family 2
PHGHKPIB_01323 3.2e-175 M Glycosyltransferase, group 2 family protein
PHGHKPIB_01324 1.8e-221 amrA S membrane protein involved in the export of O-antigen and teichoic acid
PHGHKPIB_01325 2.6e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PHGHKPIB_01326 1.4e-254 S Glucosyl transferase GtrII
PHGHKPIB_01327 1.2e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PHGHKPIB_01328 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
PHGHKPIB_01329 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PHGHKPIB_01330 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PHGHKPIB_01331 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PHGHKPIB_01332 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PHGHKPIB_01333 7.9e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
PHGHKPIB_01334 7.3e-211 arcT 2.6.1.1 E Aminotransferase
PHGHKPIB_01335 3.2e-136 ET Belongs to the bacterial solute-binding protein 3 family
PHGHKPIB_01336 4.9e-132 ET Belongs to the bacterial solute-binding protein 3 family
PHGHKPIB_01337 9.5e-80 mutT 3.6.1.55 F Nudix family
PHGHKPIB_01338 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PHGHKPIB_01340 3.3e-164 S CAAX amino terminal protease family protein
PHGHKPIB_01341 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
PHGHKPIB_01342 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
PHGHKPIB_01343 2e-149 msmR K AraC family transcriptional regulator
PHGHKPIB_01344 6.5e-70 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
PHGHKPIB_01345 1.3e-16 tcyB_2 P ABC transporter (permease)
PHGHKPIB_01346 1.2e-152 endA F DNA RNA non-specific endonuclease
PHGHKPIB_01347 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
PHGHKPIB_01348 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHGHKPIB_01350 3.3e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PHGHKPIB_01351 3.2e-134 G Domain of unknown function (DUF4832)
PHGHKPIB_01352 9.2e-84 S membrane
PHGHKPIB_01353 6.7e-96 P VTC domain
PHGHKPIB_01354 1.3e-222 cotH M CotH kinase protein
PHGHKPIB_01355 5.8e-184 pelG M Putative exopolysaccharide Exporter (EPS-E)
PHGHKPIB_01356 3.9e-270 pelF GT4 M Domain of unknown function (DUF3492)
PHGHKPIB_01357 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
PHGHKPIB_01358 1.2e-145
PHGHKPIB_01359 8.4e-278 5.1.3.2 GM Psort location CytoplasmicMembrane, score
PHGHKPIB_01360 3.5e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PHGHKPIB_01361 7.3e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PHGHKPIB_01362 5.4e-303 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHGHKPIB_01363 3.3e-86 ytsP 1.8.4.14 T GAF domain-containing protein
PHGHKPIB_01364 1.6e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PHGHKPIB_01365 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
PHGHKPIB_01368 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PHGHKPIB_01369 4.4e-110 XK27_05110 P Chloride transporter ClC family
PHGHKPIB_01370 1.7e-224 L the current gene model (or a revised gene model) may contain a frame shift
PHGHKPIB_01371 2.1e-197 ltrA S Low temperature requirement protein
PHGHKPIB_01372 4.9e-60 K sequence-specific DNA binding
PHGHKPIB_01373 1.8e-78 S membrane protein of uknown function UCP014873
PHGHKPIB_01374 4.7e-80 S Short repeat of unknown function (DUF308)
PHGHKPIB_01375 5.5e-89 K TRANSCRIPTIONal
PHGHKPIB_01376 1.2e-156 L Replication initiation factor
PHGHKPIB_01377 1.9e-18 S Domain of unknown function (DUF3173)
PHGHKPIB_01378 1.3e-215 int L Belongs to the 'phage' integrase family
PHGHKPIB_01380 5.9e-233 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
PHGHKPIB_01381 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PHGHKPIB_01382 6.3e-44 yrzL S Belongs to the UPF0297 family
PHGHKPIB_01383 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PHGHKPIB_01384 3.2e-44 yrzB S Belongs to the UPF0473 family
PHGHKPIB_01385 7e-295 ccs S the current gene model (or a revised gene model) may contain a frame shift
PHGHKPIB_01386 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PHGHKPIB_01387 7.5e-14
PHGHKPIB_01388 2.4e-89 XK27_10930 K acetyltransferase
PHGHKPIB_01389 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHGHKPIB_01390 4e-122 yaaA S Belongs to the UPF0246 family
PHGHKPIB_01391 9.3e-167 XK27_01785 S cog cog1284
PHGHKPIB_01392 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PHGHKPIB_01394 5.6e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
PHGHKPIB_01395 6.2e-32 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PHGHKPIB_01396 4.6e-118 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PHGHKPIB_01397 1.5e-219 metE 2.1.1.14 E Methionine synthase
PHGHKPIB_01398 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PHGHKPIB_01399 1.1e-80 L Helix-turn-helix domain
PHGHKPIB_01400 3.2e-145 L Integrase core domain protein
PHGHKPIB_01401 1.1e-34 S Protein of unknown function (DUF2969)
PHGHKPIB_01404 1.1e-22
PHGHKPIB_01405 2.7e-70 yxcB K Transcriptional regulator C-terminal region
PHGHKPIB_01408 6.6e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
PHGHKPIB_01409 1.6e-103 S Domain of unknown function (DUF1803)
PHGHKPIB_01410 7.8e-102 ygaC J Belongs to the UPF0374 family
PHGHKPIB_01411 8.3e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
PHGHKPIB_01412 3.8e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHGHKPIB_01413 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
PHGHKPIB_01414 3.4e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
PHGHKPIB_01415 1.8e-113 S HAD hydrolase, family IA, variant 3
PHGHKPIB_01416 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
PHGHKPIB_01417 5.2e-72 marR K Transcriptional regulator, MarR family
PHGHKPIB_01418 1.4e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PHGHKPIB_01419 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHGHKPIB_01420 4.4e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
PHGHKPIB_01421 3.6e-163 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PHGHKPIB_01422 6.2e-126 IQ reductase
PHGHKPIB_01423 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PHGHKPIB_01424 5.2e-52 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PHGHKPIB_01425 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PHGHKPIB_01426 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PHGHKPIB_01427 1e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PHGHKPIB_01428 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PHGHKPIB_01429 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PHGHKPIB_01430 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
PHGHKPIB_01431 1.4e-112 fruR K transcriptional
PHGHKPIB_01432 1.3e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PHGHKPIB_01433 2.1e-152 fruA 2.7.1.202 G phosphotransferase system
PHGHKPIB_01434 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHGHKPIB_01435 1.5e-33 ykzG S Belongs to the UPF0356 family
PHGHKPIB_01436 6.9e-119 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
PHGHKPIB_01437 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PHGHKPIB_01438 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PHGHKPIB_01439 9.7e-113 azlC E AzlC protein
PHGHKPIB_01440 1.3e-46 azlD S branched-chain amino acid
PHGHKPIB_01441 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PHGHKPIB_01442 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PHGHKPIB_01443 2.2e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHGHKPIB_01444 1.4e-26 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PHGHKPIB_01445 5.3e-90 cvpA S toxin biosynthetic process
PHGHKPIB_01446 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PHGHKPIB_01447 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PHGHKPIB_01449 1.5e-35
PHGHKPIB_01452 9.5e-214 mutY L A G-specific adenine glycosylase
PHGHKPIB_01453 2.8e-41 XK27_05745
PHGHKPIB_01454 3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
PHGHKPIB_01455 1.2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PHGHKPIB_01456 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PHGHKPIB_01458 1e-122 XK27_01040 S Protein of unknown function (DUF1129)
PHGHKPIB_01459 1e-168 corA P COG0598 Mg2 and Co2 transporters
PHGHKPIB_01460 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PHGHKPIB_01464 4.7e-32 blpT
PHGHKPIB_01465 1.8e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
PHGHKPIB_01466 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
PHGHKPIB_01467 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHGHKPIB_01468 1.7e-61 yqhY S protein conserved in bacteria
PHGHKPIB_01469 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PHGHKPIB_01470 9.2e-178 scrR K Transcriptional regulator
PHGHKPIB_01471 7.8e-290 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
PHGHKPIB_01472 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PHGHKPIB_01473 3.5e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
PHGHKPIB_01474 9e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
PHGHKPIB_01476 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHGHKPIB_01477 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PHGHKPIB_01478 1e-195 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PHGHKPIB_01479 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PHGHKPIB_01480 2.5e-203 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PHGHKPIB_01481 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PHGHKPIB_01485 3.2e-30 yozG K Transcriptional regulator
PHGHKPIB_01487 5.4e-178 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PHGHKPIB_01488 1.4e-259 XK27_03190 S hydrolases of the HAD superfamily
PHGHKPIB_01489 4.8e-104 yebC M Membrane
PHGHKPIB_01490 2.2e-310 KT response to antibiotic
PHGHKPIB_01491 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
PHGHKPIB_01492 5.5e-108 liaI S membrane
PHGHKPIB_01493 1.7e-298 O MreB/Mbl protein
PHGHKPIB_01495 5.8e-146 V Psort location CytoplasmicMembrane, score
PHGHKPIB_01498 6.8e-14
PHGHKPIB_01499 2.3e-232 dcuS 2.7.13.3 T protein histidine kinase activity
PHGHKPIB_01500 1.5e-245 2.7.13.3 T protein histidine kinase activity
PHGHKPIB_01501 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
PHGHKPIB_01502 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PHGHKPIB_01503 4.7e-126 S Protein of unknown function (DUF554)
PHGHKPIB_01504 3.1e-133 ecsA_2 V abc transporter atp-binding protein
PHGHKPIB_01505 1.4e-276 XK27_00765
PHGHKPIB_01506 7.5e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PHGHKPIB_01507 2.7e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PHGHKPIB_01508 1e-58 yhaI J Membrane
PHGHKPIB_01509 3.8e-61 yhaI J Protein of unknown function (DUF805)
PHGHKPIB_01510 3.7e-48 yhaI J Protein of unknown function (DUF805)
PHGHKPIB_01512 7.2e-96
PHGHKPIB_01513 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PHGHKPIB_01514 2.4e-45 ftsL D cell division protein FtsL
PHGHKPIB_01515 0.0 ftsI 3.4.16.4 M penicillin-binding protein
PHGHKPIB_01516 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PHGHKPIB_01517 1e-219 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PHGHKPIB_01518 3.1e-259 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PHGHKPIB_01519 5.6e-63 yutD J protein conserved in bacteria
PHGHKPIB_01520 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PHGHKPIB_01521 9.7e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
PHGHKPIB_01524 0.0 mdlA V abc transporter atp-binding protein
PHGHKPIB_01525 0.0 mdlB V abc transporter atp-binding protein
PHGHKPIB_01526 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
PHGHKPIB_01532 3.1e-44 spiA K sequence-specific DNA binding
PHGHKPIB_01533 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PHGHKPIB_01534 5.7e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
PHGHKPIB_01535 9.2e-92 V CAAX protease self-immunity
PHGHKPIB_01536 9.2e-141 cppA E CppA N-terminal
PHGHKPIB_01537 5.5e-175 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
PHGHKPIB_01539 2.4e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PHGHKPIB_01540 1e-142 cah 4.2.1.1 P carbonic anhydrase
PHGHKPIB_01541 0.0 pflB 2.3.1.54 C formate acetyltransferase'
PHGHKPIB_01542 8e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PHGHKPIB_01543 2.8e-35
PHGHKPIB_01544 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PHGHKPIB_01545 3.3e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PHGHKPIB_01546 2.3e-162 yxeN P ABC transporter (Permease
PHGHKPIB_01547 9.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
PHGHKPIB_01548 5e-10 S Protein of unknown function (DUF4059)
PHGHKPIB_01549 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PHGHKPIB_01550 4.8e-91 rsmD 2.1.1.171 L Methyltransferase
PHGHKPIB_01551 1.3e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PHGHKPIB_01552 1.2e-186 ylbL T Belongs to the peptidase S16 family
PHGHKPIB_01553 9.3e-183 yhcC S radical SAM protein
PHGHKPIB_01554 2.9e-96 ytqB J (SAM)-dependent
PHGHKPIB_01555 1.9e-07
PHGHKPIB_01556 0.0 yjcE P NhaP-type Na H and K H antiporters
PHGHKPIB_01557 1.9e-23
PHGHKPIB_01559 1.1e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
PHGHKPIB_01560 1.9e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
PHGHKPIB_01561 2.5e-10 MU outer membrane autotransporter barrel domain protein
PHGHKPIB_01562 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHGHKPIB_01564 9e-75 XK27_03180 T universal stress protein
PHGHKPIB_01565 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
PHGHKPIB_01566 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PHGHKPIB_01567 1.3e-99 pncA Q isochorismatase
PHGHKPIB_01568 1.2e-287 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHGHKPIB_01569 1.5e-217 M lipopolysaccharide 3-alpha-galactosyltransferase activity
PHGHKPIB_01570 8.2e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
PHGHKPIB_01571 1.5e-191 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PHGHKPIB_01572 2.8e-234 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PHGHKPIB_01573 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHGHKPIB_01574 5.5e-267 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PHGHKPIB_01575 5.1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHGHKPIB_01577 9.2e-283 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHGHKPIB_01578 9.4e-31 S PQ loop repeat
PHGHKPIB_01579 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
PHGHKPIB_01580 7e-273 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
PHGHKPIB_01581 1.7e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
PHGHKPIB_01582 1.5e-27
PHGHKPIB_01583 1.7e-78 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
PHGHKPIB_01584 2.2e-182 galR K Transcriptional regulator
PHGHKPIB_01585 0.0 M Putative cell wall binding repeat
PHGHKPIB_01586 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PHGHKPIB_01587 3.4e-98 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PHGHKPIB_01588 0.0 S dextransucrase activity
PHGHKPIB_01589 4.8e-72 S dextransucrase activity
PHGHKPIB_01590 7.7e-39 M Putative cell wall binding repeat
PHGHKPIB_01591 0.0 S dextransucrase activity
PHGHKPIB_01592 0.0 S dextransucrase activity
PHGHKPIB_01593 3.2e-235 S dextransucrase activity
PHGHKPIB_01594 1.9e-85 S dextransucrase activity
PHGHKPIB_01595 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
PHGHKPIB_01596 3.3e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
PHGHKPIB_01597 8.7e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PHGHKPIB_01598 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
PHGHKPIB_01599 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
PHGHKPIB_01600 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PHGHKPIB_01601 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PHGHKPIB_01602 6.4e-73 ylbF S Belongs to the UPF0342 family
PHGHKPIB_01603 1.9e-46 ylbG S UPF0298 protein
PHGHKPIB_01604 2.6e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
PHGHKPIB_01605 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
PHGHKPIB_01606 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
PHGHKPIB_01607 4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
PHGHKPIB_01608 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
PHGHKPIB_01609 6.6e-111 acuB S CBS domain
PHGHKPIB_01610 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PHGHKPIB_01611 2.2e-108 yvyE 3.4.13.9 S YigZ family
PHGHKPIB_01612 2.4e-237 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PHGHKPIB_01613 1.3e-98 comFC K competence protein
PHGHKPIB_01614 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PHGHKPIB_01615 4.1e-156 XK27_09825 V abc transporter atp-binding protein
PHGHKPIB_01616 3.2e-10 liaI KT membrane
PHGHKPIB_01617 3.9e-82 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
PHGHKPIB_01618 2.4e-53 V ABC-2 family transporter protein
PHGHKPIB_01620 3e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PHGHKPIB_01621 2e-226 T PhoQ Sensor
PHGHKPIB_01622 2.8e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PHGHKPIB_01623 3.6e-221 XK27_05470 E Methionine synthase
PHGHKPIB_01624 4.2e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PHGHKPIB_01625 1.4e-41 pspE P Rhodanese-like protein
PHGHKPIB_01626 8.2e-137 IQ Acetoin reductase
PHGHKPIB_01628 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PHGHKPIB_01631 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PHGHKPIB_01632 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PHGHKPIB_01633 8.9e-40 C Pyridoxamine 5'-phosphate oxidase
PHGHKPIB_01634 2.4e-94 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
PHGHKPIB_01635 9.2e-80 S Macro domain
PHGHKPIB_01636 4.1e-72 mgrA K Transcriptional regulator, MarR family
PHGHKPIB_01637 3.7e-138 1.6.5.2 GM epimerase
PHGHKPIB_01638 3.9e-128 proV E abc transporter atp-binding protein
PHGHKPIB_01639 4.4e-275 proWX P ABC transporter
PHGHKPIB_01640 1.1e-110 magIII L Base excision DNA repair protein, HhH-GPD family
PHGHKPIB_01641 6e-283 V (ABC) transporter
PHGHKPIB_01642 2.4e-142 K sequence-specific DNA binding
PHGHKPIB_01643 4.6e-244 norM V Multidrug efflux pump
PHGHKPIB_01645 1.9e-183 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHGHKPIB_01646 8.1e-233 brnQ E Component of the transport system for branched-chain amino acids
PHGHKPIB_01647 1.7e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
PHGHKPIB_01648 5.8e-58 S Protein of unknown function (DUF3290)
PHGHKPIB_01649 5.4e-102 S Protein of unknown function (DUF421)
PHGHKPIB_01650 1.4e-16 csbD S CsbD-like
PHGHKPIB_01651 1.3e-101 S Carbohydrate-binding domain-containing protein Cthe_2159
PHGHKPIB_01652 7.4e-37 XK27_01300 S ASCH
PHGHKPIB_01653 2.5e-213 yfnA E amino acid
PHGHKPIB_01654 0.0 S dextransucrase activity
PHGHKPIB_01655 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PHGHKPIB_01656 1.5e-42 S Sugar efflux transporter for intercellular exchange
PHGHKPIB_01657 3.4e-203 P FtsX-like permease family
PHGHKPIB_01658 1.5e-121 V abc transporter atp-binding protein
PHGHKPIB_01659 3.2e-133 macB2 V ABC transporter, ATP-binding protein
PHGHKPIB_01660 9.3e-133 macB2 V ABC transporter, ATP-binding protein
PHGHKPIB_01661 3.6e-114 pscB M CHAP domain protein
PHGHKPIB_01662 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
PHGHKPIB_01663 2.5e-62 glnR K Transcriptional regulator
PHGHKPIB_01664 3e-87 S Fusaric acid resistance protein-like
PHGHKPIB_01665 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PHGHKPIB_01666 1.9e-186 gap 1.2.1.12 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PHGHKPIB_01667 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PHGHKPIB_01668 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PHGHKPIB_01669 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PHGHKPIB_01670 4e-142 purR 2.4.2.7 F operon repressor
PHGHKPIB_01671 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
PHGHKPIB_01672 1.6e-169 rmuC S RmuC domain protein
PHGHKPIB_01673 3.8e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
PHGHKPIB_01674 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PHGHKPIB_01675 1.2e-160 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PHGHKPIB_01677 2.6e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PHGHKPIB_01678 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PHGHKPIB_01679 1.6e-143 tatD L Hydrolase, tatd
PHGHKPIB_01680 1.2e-73 yccU S CoA-binding protein
PHGHKPIB_01681 2.4e-50 trxA O Belongs to the thioredoxin family
PHGHKPIB_01682 1.7e-142 S Macro domain protein
PHGHKPIB_01683 1.8e-61 L thioesterase
PHGHKPIB_01684 1.6e-52 bta 1.8.1.8 CO cell redox homeostasis
PHGHKPIB_01686 4.9e-108 XK27_09825 V abc transporter atp-binding protein
PHGHKPIB_01687 3.4e-132 yvfS V ABC-2 type transporter
PHGHKPIB_01688 4.5e-189 desK 2.7.13.3 T Histidine kinase
PHGHKPIB_01689 5.7e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PHGHKPIB_01690 6.3e-205 S Protein of unknown function DUF262
PHGHKPIB_01691 8.8e-125 S Protein of unknown function DUF262
PHGHKPIB_01692 2.8e-84 yfjR K regulation of single-species biofilm formation
PHGHKPIB_01695 1.8e-184 S abc transporter atp-binding protein
PHGHKPIB_01696 2e-141 S ABC-2 family transporter protein
PHGHKPIB_01697 3.3e-141 S ABC-2 family transporter protein
PHGHKPIB_01698 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
PHGHKPIB_01699 8.1e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PHGHKPIB_01700 1.8e-19
PHGHKPIB_01701 1.5e-29 K Helix-turn-helix domain
PHGHKPIB_01703 2e-149 srtB 3.4.22.70 S Sortase family
PHGHKPIB_01704 1.5e-233 capA M Bacterial capsule synthesis protein
PHGHKPIB_01705 1e-38 gcvR T UPF0237 protein
PHGHKPIB_01706 2.8e-241 XK27_08635 S UPF0210 protein
PHGHKPIB_01707 4e-23 ais G alpha-ribazole phosphatase activity
PHGHKPIB_01708 8.2e-93 ais G Phosphoglycerate mutase
PHGHKPIB_01709 1e-137 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PHGHKPIB_01710 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
PHGHKPIB_01711 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PHGHKPIB_01712 6.3e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PHGHKPIB_01713 1.1e-301 dnaK O Heat shock 70 kDa protein
PHGHKPIB_01714 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PHGHKPIB_01715 5.9e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PHGHKPIB_01716 1.8e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
PHGHKPIB_01717 1.3e-79 hmpT S cog cog4720
PHGHKPIB_01718 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PHGHKPIB_01719 4.7e-88 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PHGHKPIB_01720 1e-75 fld C Flavodoxin
PHGHKPIB_01721 4.8e-18 XK27_08880
PHGHKPIB_01722 1.6e-126 XK27_08875 O Zinc-dependent metalloprotease
PHGHKPIB_01723 4.7e-148 estA CE1 S Esterase
PHGHKPIB_01724 1.3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHGHKPIB_01725 7.6e-135 XK27_08845 S abc transporter atp-binding protein
PHGHKPIB_01726 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
PHGHKPIB_01727 4.3e-178 XK27_08835 S ABC transporter substrate binding protein
PHGHKPIB_01728 3.8e-18 S Domain of unknown function (DUF4649)
PHGHKPIB_01729 0.0 Q the current gene model (or a revised gene model) may contain a frame shift
PHGHKPIB_01730 5e-223 rgpA GT4 M Domain of unknown function (DUF1972)
PHGHKPIB_01731 6.1e-221 rgpA GT4 M Domain of unknown function (DUF1972)
PHGHKPIB_01732 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PHGHKPIB_01733 6.3e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
PHGHKPIB_01734 2.5e-121 sdaAB 4.3.1.17 E L-serine dehydratase
PHGHKPIB_01735 1.7e-146 sdaAA 4.3.1.17 E L-serine dehydratase
PHGHKPIB_01736 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
PHGHKPIB_01737 1.1e-145 yjlA EG membrane
PHGHKPIB_01738 2.1e-80 3.4.21.89 S RDD family
PHGHKPIB_01739 4.2e-164 K sequence-specific DNA binding
PHGHKPIB_01740 8.9e-153 V ABC transporter, ATP-binding protein
PHGHKPIB_01741 2.3e-96 S ABC-2 family transporter protein
PHGHKPIB_01742 1.8e-130 K sequence-specific DNA binding
PHGHKPIB_01743 3.5e-51 ywrO S general stress protein
PHGHKPIB_01744 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
PHGHKPIB_01746 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHGHKPIB_01747 5.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PHGHKPIB_01748 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PHGHKPIB_01749 6.6e-22 WQ51_00220 K Helix-turn-helix domain
PHGHKPIB_01750 2.4e-90 S Protein of unknown function (DUF3278)
PHGHKPIB_01751 0.0 smc D Required for chromosome condensation and partitioning
PHGHKPIB_01752 6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PHGHKPIB_01753 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PHGHKPIB_01754 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PHGHKPIB_01756 9.4e-189 adhP 1.1.1.1 C alcohol dehydrogenase
PHGHKPIB_01757 1e-44
PHGHKPIB_01758 2.9e-50
PHGHKPIB_01759 3.3e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PHGHKPIB_01760 1.8e-156 aatB ET ABC transporter substrate-binding protein
PHGHKPIB_01761 2e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
PHGHKPIB_01762 3.1e-105 artQ P ABC transporter (Permease
PHGHKPIB_01763 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
PHGHKPIB_01764 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PHGHKPIB_01765 2.2e-165 cpsY K Transcriptional regulator
PHGHKPIB_01766 9.3e-127 mur1 3.4.17.14, 3.5.1.28 NU muramidase
PHGHKPIB_01767 1.8e-168 yeiH S Membrane
PHGHKPIB_01769 3.4e-09
PHGHKPIB_01770 4.4e-291 adcA P Belongs to the bacterial solute-binding protein 9 family
PHGHKPIB_01771 3.5e-146 XK27_10720 D peptidase activity
PHGHKPIB_01772 2.6e-192 pbuX F xanthine permease
PHGHKPIB_01773 8e-177 GT4 M transferase activity, transferring glycosyl groups
PHGHKPIB_01774 5.2e-67 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
PHGHKPIB_01775 2e-58 arsC 1.20.4.1 P Belongs to the ArsC family
PHGHKPIB_01777 3.5e-56 lrgA S Effector of murein hydrolase LrgA
PHGHKPIB_01778 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PHGHKPIB_01779 3.2e-98 3.1.3.18 S IA, variant 1
PHGHKPIB_01780 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHGHKPIB_01781 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PHGHKPIB_01782 7.7e-112 serB 3.1.3.3 E phosphoserine phosphatase
PHGHKPIB_01783 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PHGHKPIB_01784 1.3e-159 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHGHKPIB_01785 5.9e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHGHKPIB_01786 1.4e-105 csn2 S CRISPR-associated protein (Cas_Csn2)
PHGHKPIB_01787 1.2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
PHGHKPIB_01788 2.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PHGHKPIB_01789 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PHGHKPIB_01790 8.8e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PHGHKPIB_01791 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PHGHKPIB_01792 2.7e-126 gntR1 K transcriptional
PHGHKPIB_01793 3.9e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PHGHKPIB_01794 3.8e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PHGHKPIB_01795 1.3e-85
PHGHKPIB_01796 3.9e-90 niaR S small molecule binding protein (contains 3H domain)
PHGHKPIB_01797 1.5e-126 K DNA-binding helix-turn-helix protein
PHGHKPIB_01798 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PHGHKPIB_01799 4.2e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHGHKPIB_01800 1e-165 GK ROK family
PHGHKPIB_01801 7.8e-157 dprA LU DNA protecting protein DprA
PHGHKPIB_01802 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PHGHKPIB_01803 1e-73 ybhL S Inhibitor of apoptosis-promoting Bax1
PHGHKPIB_01804 6.1e-93 XK27_05000 S metal cluster binding
PHGHKPIB_01805 1.2e-59 V ABC transporter (permease)
PHGHKPIB_01806 3.4e-143 manA 5.3.1.8 G Phosphomannose isomerase type I
PHGHKPIB_01807 6.4e-84 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PHGHKPIB_01808 1.7e-90 adk 2.7.4.3 F topology modulation protein
PHGHKPIB_01809 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PHGHKPIB_01810 2.2e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PHGHKPIB_01811 2.8e-35 XK27_09805 S MORN repeat protein
PHGHKPIB_01812 0.0 XK27_09800 I Acyltransferase
PHGHKPIB_01813 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PHGHKPIB_01814 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
PHGHKPIB_01815 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PHGHKPIB_01816 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
PHGHKPIB_01817 9.2e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PHGHKPIB_01818 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PHGHKPIB_01819 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PHGHKPIB_01820 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PHGHKPIB_01821 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PHGHKPIB_01822 4.5e-92 yocS S Transporter
PHGHKPIB_01823 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PHGHKPIB_01824 4.2e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PHGHKPIB_01825 1.1e-223 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PHGHKPIB_01826 8.8e-212 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
PHGHKPIB_01828 3.2e-231 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PHGHKPIB_01829 7.9e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PHGHKPIB_01830 1.5e-187 fruA 2.7.1.202 G phosphotransferase system
PHGHKPIB_01831 2e-62 drgA C nitroreductase
PHGHKPIB_01832 9.6e-121 T Transcriptional regulatory protein, C terminal
PHGHKPIB_01833 1.4e-129 T PhoQ Sensor
PHGHKPIB_01834 9.4e-45 S Domain of unknown function (DUF4352)
PHGHKPIB_01835 2.3e-128 S ABC-2 family transporter protein
PHGHKPIB_01836 1.7e-168 bcrA V abc transporter atp-binding protein
PHGHKPIB_01837 1.3e-227 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHGHKPIB_01838 2.2e-154 E Alpha/beta hydrolase of unknown function (DUF915)
PHGHKPIB_01839 2.5e-77 ywnA K Transcriptional regulator
PHGHKPIB_01840 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PHGHKPIB_01841 1.9e-23 rpmD J ribosomal protein l30
PHGHKPIB_01842 1.7e-57 rplO J binds to the 23S rRNA
PHGHKPIB_01843 6.2e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PHGHKPIB_01844 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PHGHKPIB_01845 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PHGHKPIB_01846 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PHGHKPIB_01847 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PHGHKPIB_01848 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PHGHKPIB_01849 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHGHKPIB_01850 4.4e-62 rplQ J ribosomal protein l17
PHGHKPIB_01851 7.4e-239 6.3.2.2 H gamma-glutamylcysteine synthetase
PHGHKPIB_01853 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
PHGHKPIB_01854 1.5e-70
PHGHKPIB_01855 1.3e-92
PHGHKPIB_01858 1.9e-95 ywlG S Belongs to the UPF0340 family
PHGHKPIB_01859 7.9e-126 treR K trehalose operon
PHGHKPIB_01860 9.5e-291 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PHGHKPIB_01861 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PHGHKPIB_01862 0.0 pepO 3.4.24.71 O Peptidase family M13
PHGHKPIB_01863 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PHGHKPIB_01866 1.3e-276 thrC 4.2.3.1 E Threonine synthase
PHGHKPIB_01867 7.1e-226 norN V Mate efflux family protein
PHGHKPIB_01868 1.4e-57 asp S cog cog1302
PHGHKPIB_01869 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
PHGHKPIB_01870 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PHGHKPIB_01871 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
PHGHKPIB_01872 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
PHGHKPIB_01873 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PHGHKPIB_01874 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PHGHKPIB_01875 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PHGHKPIB_01876 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHGHKPIB_01877 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHGHKPIB_01878 1e-68 S cog cog4699
PHGHKPIB_01879 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PHGHKPIB_01880 2.2e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PHGHKPIB_01881 5e-43 comGC U Required for transformation and DNA binding
PHGHKPIB_01882 9.8e-68 cglD NU Competence protein
PHGHKPIB_01883 5.3e-15 NU Type II secretory pathway pseudopilin
PHGHKPIB_01884 5.4e-69 comGF U Competence protein ComGF
PHGHKPIB_01885 2e-12 comGF U Putative Competence protein ComGF
PHGHKPIB_01886 5e-176 ytxK 2.1.1.72 L DNA methylase
PHGHKPIB_01887 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHGHKPIB_01888 1.3e-25 lanR K sequence-specific DNA binding
PHGHKPIB_01889 2.1e-104 V CAAX protease self-immunity
PHGHKPIB_01891 9.6e-102 S CAAX amino terminal protease family protein
PHGHKPIB_01892 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PHGHKPIB_01893 7e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PHGHKPIB_01894 2.7e-08 XK27_10305 S Domain of unknown function (DUF4651)
PHGHKPIB_01895 4.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PHGHKPIB_01897 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHGHKPIB_01898 2e-186 yeeE S Sulphur transport
PHGHKPIB_01899 8.3e-37 yeeD O sulfur carrier activity
PHGHKPIB_01900 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PHGHKPIB_01901 1.9e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PHGHKPIB_01905 9.8e-160 rrmA 2.1.1.187 Q methyltransferase
PHGHKPIB_01906 2.4e-141 S HAD hydrolase, family IA, variant
PHGHKPIB_01907 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PHGHKPIB_01908 4.6e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PHGHKPIB_01909 2.2e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PHGHKPIB_01910 5.7e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
PHGHKPIB_01911 1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PHGHKPIB_01912 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PHGHKPIB_01913 1.8e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
PHGHKPIB_01914 2.4e-139 fnt P Formate nitrite transporter
PHGHKPIB_01915 2.1e-230 XK27_09615 C reductase
PHGHKPIB_01916 3.1e-107 XK27_09620 S FMN reductase (NADPH) activity
PHGHKPIB_01917 5e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PHGHKPIB_01918 8.7e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PHGHKPIB_01919 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PHGHKPIB_01920 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
PHGHKPIB_01921 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
PHGHKPIB_01922 1.2e-50 S Protein of unknown function (DUF3397)
PHGHKPIB_01923 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PHGHKPIB_01924 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PHGHKPIB_01925 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PHGHKPIB_01926 6.7e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PHGHKPIB_01927 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
PHGHKPIB_01928 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
PHGHKPIB_01929 2.4e-210 hpk9 2.7.13.3 T protein histidine kinase activity
PHGHKPIB_01930 1.2e-223 fasC 2.7.13.3 T protein histidine kinase activity
PHGHKPIB_01931 7.2e-130 fasA KT Response regulator of the LytR AlgR family
PHGHKPIB_01932 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PHGHKPIB_01933 7.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
PHGHKPIB_01934 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PHGHKPIB_01935 2.2e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHGHKPIB_01936 5.5e-152 jag S RNA-binding protein
PHGHKPIB_01937 8.4e-105 K Transcriptional regulator
PHGHKPIB_01938 6.3e-102 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
PHGHKPIB_01939 3.4e-14 rpmH J Ribosomal protein L34
PHGHKPIB_01940 1.8e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PHGHKPIB_01942 1.8e-96 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
PHGHKPIB_01943 1.1e-19 K Transcriptional regulator
PHGHKPIB_01944 4.7e-17 K Transcriptional regulator
PHGHKPIB_01945 1.4e-62 K WHG domain
PHGHKPIB_01946 2.7e-96 cylB V ABC-2 type transporter
PHGHKPIB_01947 7.8e-110 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
PHGHKPIB_01948 1.6e-26 acpT 2.7.8.7 H lysine biosynthetic process via aminoadipic acid
PHGHKPIB_01949 3.1e-298 MA20_06650 IQ Polyketide synthase dehydratase
PHGHKPIB_01950 7.7e-18 XK27_00735
PHGHKPIB_01951 1.3e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PHGHKPIB_01953 1.5e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PHGHKPIB_01954 2e-10 O ADP-ribosylglycohydrolase
PHGHKPIB_01955 3.3e-62 paaI Q protein possibly involved in aromatic compounds catabolism
PHGHKPIB_01956 6e-61 ycaO O OsmC-like protein
PHGHKPIB_01958 1.8e-151 EG Permeases of the drug metabolite transporter (DMT) superfamily
PHGHKPIB_01959 2.5e-07 N PFAM Uncharacterised protein family UPF0150
PHGHKPIB_01960 1.9e-97 yoaK S Protein of unknown function (DUF1275)
PHGHKPIB_01961 2.4e-110 drgA C nitroreductase
PHGHKPIB_01962 8.4e-227 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHGHKPIB_01963 2.8e-154 E Alpha/beta hydrolase of unknown function (DUF915)
PHGHKPIB_01964 2.3e-75 ywnA K Transcriptional regulator
PHGHKPIB_01965 2.7e-149 1.13.11.2 S glyoxalase
PHGHKPIB_01966 5.7e-109 XK27_02070 S nitroreductase
PHGHKPIB_01967 3.1e-167 ydhF S Aldo keto reductase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)