ORF_ID e_value Gene_name EC_number CAZy COGs Description
EAFICOLK_00001 1.6e-197 dtpT U amino acid peptide transporter
EAFICOLK_00002 1.1e-07
EAFICOLK_00004 4.6e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EAFICOLK_00005 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
EAFICOLK_00006 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EAFICOLK_00007 8e-242 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EAFICOLK_00008 1.8e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EAFICOLK_00009 1.3e-251 yhgF K Tex-like protein N-terminal domain protein
EAFICOLK_00010 3.6e-44 ydcK S Belongs to the SprT family
EAFICOLK_00012 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EAFICOLK_00013 7.7e-129 mleP2 S Sodium Bile acid symporter family
EAFICOLK_00014 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EAFICOLK_00015 1e-33 S Enterocin A Immunity
EAFICOLK_00016 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
EAFICOLK_00017 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
EAFICOLK_00018 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
EAFICOLK_00019 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EAFICOLK_00020 8.2e-154 yacL S domain protein
EAFICOLK_00021 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAFICOLK_00022 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EAFICOLK_00023 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EAFICOLK_00024 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAFICOLK_00025 7e-71 yacP S YacP-like NYN domain
EAFICOLK_00026 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EAFICOLK_00027 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EAFICOLK_00028 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
EAFICOLK_00029 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EAFICOLK_00030 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EAFICOLK_00031 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EAFICOLK_00032 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EAFICOLK_00033 1.4e-54
EAFICOLK_00034 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EAFICOLK_00035 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAFICOLK_00036 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAFICOLK_00037 4.8e-45 nrdI F NrdI Flavodoxin like
EAFICOLK_00038 2.7e-27 nrdH O Glutaredoxin
EAFICOLK_00039 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
EAFICOLK_00040 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EAFICOLK_00041 5.1e-211 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EAFICOLK_00042 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EAFICOLK_00043 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EAFICOLK_00044 9.2e-29 yaaL S Protein of unknown function (DUF2508)
EAFICOLK_00045 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EAFICOLK_00046 1e-83 holB 2.7.7.7 L DNA polymerase III
EAFICOLK_00047 1.4e-40 yabA L Involved in initiation control of chromosome replication
EAFICOLK_00048 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EAFICOLK_00049 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
EAFICOLK_00050 4.5e-140 ansA 3.5.1.1 EJ Asparaginase
EAFICOLK_00051 2.8e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
EAFICOLK_00052 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
EAFICOLK_00053 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EAFICOLK_00054 1.9e-254 uup S ABC transporter, ATP-binding protein
EAFICOLK_00055 1.3e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EAFICOLK_00056 5.3e-33 S CAAX protease self-immunity
EAFICOLK_00057 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EAFICOLK_00058 1.3e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EAFICOLK_00059 1.3e-265 aha1 P COG COG0474 Cation transport ATPase
EAFICOLK_00060 6.4e-297 ydaO E amino acid
EAFICOLK_00061 1.2e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
EAFICOLK_00062 1.2e-127 comFA L Helicase C-terminal domain protein
EAFICOLK_00063 1e-45 comFC S Competence protein
EAFICOLK_00064 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAFICOLK_00065 2.9e-93 yeaN P Major Facilitator Superfamily
EAFICOLK_00066 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EAFICOLK_00067 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EAFICOLK_00068 4.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
EAFICOLK_00069 6e-86 K response regulator
EAFICOLK_00070 1.2e-85 phoR 2.7.13.3 T Histidine kinase
EAFICOLK_00071 4.1e-08 KT PspC domain protein
EAFICOLK_00072 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
EAFICOLK_00073 2.5e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EAFICOLK_00074 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EAFICOLK_00075 1.4e-272 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EAFICOLK_00076 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EAFICOLK_00077 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EAFICOLK_00078 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EAFICOLK_00079 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
EAFICOLK_00080 7.5e-126 rapZ S Displays ATPase and GTPase activities
EAFICOLK_00081 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EAFICOLK_00082 1.8e-149 whiA K May be required for sporulation
EAFICOLK_00083 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EAFICOLK_00085 2.9e-137 cggR K Putative sugar-binding domain
EAFICOLK_00086 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EAFICOLK_00087 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EAFICOLK_00088 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EAFICOLK_00089 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EAFICOLK_00090 2.2e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAFICOLK_00091 5e-104 K response regulator
EAFICOLK_00092 2.4e-169 T PhoQ Sensor
EAFICOLK_00093 1.9e-145 lmrP E Major Facilitator Superfamily
EAFICOLK_00094 9.2e-180 clcA P chloride
EAFICOLK_00095 2.8e-19 secG U Preprotein translocase
EAFICOLK_00096 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EAFICOLK_00097 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EAFICOLK_00098 4.1e-42 yxjI
EAFICOLK_00099 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
EAFICOLK_00100 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EAFICOLK_00101 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EAFICOLK_00102 2.5e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
EAFICOLK_00103 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
EAFICOLK_00104 1.2e-115 murB 1.3.1.98 M Cell wall formation
EAFICOLK_00105 2.4e-71 S Protein of unknown function (DUF1361)
EAFICOLK_00106 2.9e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EAFICOLK_00107 5.3e-68 ybbR S YbbR-like protein
EAFICOLK_00108 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAFICOLK_00109 3.7e-28 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
EAFICOLK_00110 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
EAFICOLK_00111 4.2e-21 cutC P Participates in the control of copper homeostasis
EAFICOLK_00112 4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EAFICOLK_00113 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EAFICOLK_00114 6.4e-61 ybaK J Aminoacyl-tRNA editing domain
EAFICOLK_00115 5.8e-99 rrmA 2.1.1.187 H Methyltransferase
EAFICOLK_00116 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EAFICOLK_00117 1.6e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
EAFICOLK_00118 1.2e-108 ymfF S Peptidase M16 inactive domain protein
EAFICOLK_00119 1.3e-147 ymfH S Peptidase M16
EAFICOLK_00120 4.9e-91 IQ Enoyl-(Acyl carrier protein) reductase
EAFICOLK_00121 1.5e-63 ymfM S Helix-turn-helix domain
EAFICOLK_00122 1.6e-84 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EAFICOLK_00123 9.3e-161 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EAFICOLK_00124 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
EAFICOLK_00125 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EAFICOLK_00126 2.2e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EAFICOLK_00127 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EAFICOLK_00128 2.8e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EAFICOLK_00129 1e-182 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EAFICOLK_00130 7.8e-208 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EAFICOLK_00131 1.4e-12 yajC U Preprotein translocase
EAFICOLK_00133 4.3e-61 uspA T universal stress protein
EAFICOLK_00135 2e-208 yfnA E Amino Acid
EAFICOLK_00136 6.9e-117 lutA C Cysteine-rich domain
EAFICOLK_00137 1.1e-244 lutB C 4Fe-4S dicluster domain
EAFICOLK_00138 2.3e-64 yrjD S LUD domain
EAFICOLK_00139 8e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAFICOLK_00140 7.5e-13
EAFICOLK_00141 1.6e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
EAFICOLK_00142 1e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EAFICOLK_00143 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EAFICOLK_00144 2.1e-36 yrzL S Belongs to the UPF0297 family
EAFICOLK_00145 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EAFICOLK_00146 1.9e-33 yrzB S Belongs to the UPF0473 family
EAFICOLK_00147 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EAFICOLK_00148 2.9e-14 cvpA S Colicin V production protein
EAFICOLK_00149 5.5e-309 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EAFICOLK_00150 9.9e-41 trxA O Belongs to the thioredoxin family
EAFICOLK_00151 1.1e-60 yslB S Protein of unknown function (DUF2507)
EAFICOLK_00152 5e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EAFICOLK_00153 1.5e-41 S Phosphoesterase
EAFICOLK_00156 4.6e-131 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAFICOLK_00157 1.9e-306 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EAFICOLK_00158 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EAFICOLK_00159 1.9e-200 oatA I Acyltransferase
EAFICOLK_00160 1.8e-16
EAFICOLK_00162 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EAFICOLK_00163 7.6e-101 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
EAFICOLK_00164 1.4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
EAFICOLK_00165 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EAFICOLK_00166 3.5e-296 S membrane
EAFICOLK_00167 2.3e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
EAFICOLK_00168 1.8e-27 S Protein of unknown function (DUF3290)
EAFICOLK_00169 1.5e-75 yviA S Protein of unknown function (DUF421)
EAFICOLK_00171 3.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EAFICOLK_00172 2.2e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EAFICOLK_00173 3.8e-54 tag 3.2.2.20 L glycosylase
EAFICOLK_00174 3.2e-73 usp6 T universal stress protein
EAFICOLK_00176 5.2e-189 rarA L recombination factor protein RarA
EAFICOLK_00177 2e-24 yueI S Protein of unknown function (DUF1694)
EAFICOLK_00178 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EAFICOLK_00179 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
EAFICOLK_00180 8.4e-174 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EAFICOLK_00181 2.2e-162 iscS2 2.8.1.7 E Aminotransferase class V
EAFICOLK_00182 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAFICOLK_00183 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EAFICOLK_00184 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EAFICOLK_00185 6.2e-80 radC L DNA repair protein
EAFICOLK_00186 4.5e-21 K Cold shock
EAFICOLK_00187 3.6e-156 mreB D cell shape determining protein MreB
EAFICOLK_00188 2.1e-88 mreC M Involved in formation and maintenance of cell shape
EAFICOLK_00189 1.5e-54 mreD M rod shape-determining protein MreD
EAFICOLK_00190 1.1e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EAFICOLK_00191 1.8e-126 minD D Belongs to the ParA family
EAFICOLK_00192 1.9e-94 glnP P ABC transporter permease
EAFICOLK_00193 1.4e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EAFICOLK_00194 1.8e-108 aatB ET ABC transporter substrate-binding protein
EAFICOLK_00195 9.8e-100 D Alpha beta
EAFICOLK_00197 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
EAFICOLK_00199 1.5e-55 mraZ K Belongs to the MraZ family
EAFICOLK_00200 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EAFICOLK_00201 2.5e-11 ftsL D cell division protein FtsL
EAFICOLK_00202 1.2e-281 ftsI 3.4.16.4 M Penicillin-binding Protein
EAFICOLK_00203 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EAFICOLK_00204 2.6e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EAFICOLK_00205 8.9e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EAFICOLK_00206 2.2e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EAFICOLK_00207 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EAFICOLK_00208 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EAFICOLK_00209 3.8e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EAFICOLK_00210 3e-19 yggT S YGGT family
EAFICOLK_00211 3.5e-82 ylmH S S4 domain protein
EAFICOLK_00212 1.9e-61 divIVA D DivIVA domain protein
EAFICOLK_00213 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EAFICOLK_00214 5.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EAFICOLK_00215 4.4e-74 draG O ADP-ribosylglycohydrolase
EAFICOLK_00218 1.4e-06
EAFICOLK_00219 8.8e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EAFICOLK_00220 1.7e-54 rplI J Binds to the 23S rRNA
EAFICOLK_00221 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EAFICOLK_00222 4e-64 C FMN binding
EAFICOLK_00223 2.8e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EAFICOLK_00225 5.1e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EAFICOLK_00226 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
EAFICOLK_00227 1e-11 S CAAX protease self-immunity
EAFICOLK_00228 1.6e-81 S Belongs to the UPF0246 family
EAFICOLK_00229 1.8e-99 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EAFICOLK_00230 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EAFICOLK_00231 3.6e-210 glnP P ABC transporter
EAFICOLK_00233 2.9e-60 uspA T Universal stress protein family
EAFICOLK_00234 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
EAFICOLK_00235 1.1e-25
EAFICOLK_00236 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EAFICOLK_00237 6.1e-110 puuD S peptidase C26
EAFICOLK_00238 4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAFICOLK_00239 4.3e-150 lsa S ABC transporter
EAFICOLK_00240 4.2e-149 mepA V MATE efflux family protein
EAFICOLK_00243 9.8e-78 asp1 S Accessory Sec system protein Asp1
EAFICOLK_00244 7.1e-66 secY2 U SecY translocase
EAFICOLK_00245 8.3e-138 S interspecies interaction between organisms
EAFICOLK_00246 7.2e-208 G glycerol-3-phosphate transporter
EAFICOLK_00247 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EAFICOLK_00248 3.7e-145 htrA 3.4.21.107 O serine protease
EAFICOLK_00249 1.3e-116 vicX 3.1.26.11 S domain protein
EAFICOLK_00250 3.9e-16 yyaQ S YjbR
EAFICOLK_00251 3.6e-79 yycI S YycH protein
EAFICOLK_00252 1.6e-103 yycH S YycH protein
EAFICOLK_00253 1.5e-272 vicK 2.7.13.3 T Histidine kinase
EAFICOLK_00254 9e-114 K response regulator
EAFICOLK_00255 4.7e-106 yxeH S hydrolase
EAFICOLK_00256 1.1e-229 V ABC transporter transmembrane region
EAFICOLK_00257 2e-215 XK27_09600 V ABC transporter, ATP-binding protein
EAFICOLK_00258 1.2e-31 K Transcriptional regulator, MarR family
EAFICOLK_00259 2.9e-172 S Putative peptidoglycan binding domain
EAFICOLK_00260 4e-23 relB L RelB antitoxin
EAFICOLK_00261 3.8e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EAFICOLK_00262 4.4e-92 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
EAFICOLK_00263 2.9e-115 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
EAFICOLK_00264 1.1e-118 IQ KR domain
EAFICOLK_00265 2e-170 gatC G PTS system sugar-specific permease component
EAFICOLK_00266 2.2e-73 K DeoR C terminal sensor domain
EAFICOLK_00267 2.2e-36 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EAFICOLK_00268 4e-28 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
EAFICOLK_00269 1.5e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
EAFICOLK_00270 1.1e-177 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EAFICOLK_00271 2.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EAFICOLK_00272 5.1e-222 pepF E Oligopeptidase F
EAFICOLK_00273 1.7e-96 yicL EG EamA-like transporter family
EAFICOLK_00274 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
EAFICOLK_00275 1.7e-169 yjjP S Putative threonine/serine exporter
EAFICOLK_00276 1.1e-108 glcU U sugar transport
EAFICOLK_00277 3.8e-14 yobS K transcriptional regulator
EAFICOLK_00278 3.8e-152 mdtG EGP Major facilitator Superfamily
EAFICOLK_00279 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EAFICOLK_00280 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
EAFICOLK_00281 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAFICOLK_00282 3.6e-17 yneR
EAFICOLK_00283 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EAFICOLK_00284 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EAFICOLK_00285 3.3e-12 yiiE S Protein of unknown function (DUF1211)
EAFICOLK_00286 3.7e-37 yiiE S Protein of unknown function (DUF1211)
EAFICOLK_00287 0.0 asnB 6.3.5.4 E Asparagine synthase
EAFICOLK_00288 7.4e-64 D peptidase
EAFICOLK_00289 5.6e-117 S Glycosyl transferase family 2
EAFICOLK_00290 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
EAFICOLK_00291 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EAFICOLK_00292 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EAFICOLK_00293 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
EAFICOLK_00294 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EAFICOLK_00295 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EAFICOLK_00296 2.9e-154 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EAFICOLK_00297 9e-20 yaaA S S4 domain protein YaaA
EAFICOLK_00298 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EAFICOLK_00299 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EAFICOLK_00300 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
EAFICOLK_00301 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EAFICOLK_00302 4.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EAFICOLK_00303 1.1e-199 nupG F Nucleoside
EAFICOLK_00304 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
EAFICOLK_00305 1.7e-53 K LysR substrate binding domain
EAFICOLK_00306 1.8e-07
EAFICOLK_00307 7.9e-66 yxkH G Polysaccharide deacetylase
EAFICOLK_00308 9e-30 yqkB S Belongs to the HesB IscA family
EAFICOLK_00309 4.5e-44 L PLD-like domain
EAFICOLK_00311 6.1e-08 yokH G regulation of fungal-type cell wall biogenesis
EAFICOLK_00312 9.4e-109 L Initiator Replication protein
EAFICOLK_00313 5.1e-38 S Replication initiator protein A (RepA) N-terminus
EAFICOLK_00314 5.7e-102 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EAFICOLK_00315 3.5e-104 2.7.1.199, 2.7.1.208 G .Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome down-regulated in Spo0A mutant
EAFICOLK_00316 6e-17 bglG K antiterminator
EAFICOLK_00317 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
EAFICOLK_00319 6.4e-36
EAFICOLK_00321 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EAFICOLK_00322 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EAFICOLK_00323 3.1e-192 cycA E Amino acid permease
EAFICOLK_00324 8.3e-187 ytgP S Polysaccharide biosynthesis protein
EAFICOLK_00325 7.4e-63 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EAFICOLK_00326 2.4e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EAFICOLK_00327 6.6e-193 pepV 3.5.1.18 E dipeptidase PepV
EAFICOLK_00328 1.4e-62 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
EAFICOLK_00329 5e-66 2.1.1.72, 3.1.21.4 L Eco57I restriction-modification methylase
EAFICOLK_00330 0.0 L Type III restriction enzyme, res subunit
EAFICOLK_00331 2.5e-182 S Protein of unknown function DUF262
EAFICOLK_00333 5.2e-36
EAFICOLK_00334 3.4e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EAFICOLK_00335 4.2e-61 marR K Transcriptional regulator, MarR family
EAFICOLK_00336 7.1e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EAFICOLK_00337 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAFICOLK_00338 5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EAFICOLK_00339 6.5e-99 IQ reductase
EAFICOLK_00340 4.8e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EAFICOLK_00341 6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EAFICOLK_00342 8.7e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EAFICOLK_00343 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
EAFICOLK_00344 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EAFICOLK_00345 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
EAFICOLK_00346 1.6e-108 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EAFICOLK_00347 9.5e-230 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EAFICOLK_00348 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
EAFICOLK_00349 1.2e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EAFICOLK_00350 5.7e-119 gla U Major intrinsic protein
EAFICOLK_00351 5.8e-45 ykuL S CBS domain
EAFICOLK_00352 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EAFICOLK_00353 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EAFICOLK_00354 9e-87 ykuT M mechanosensitive ion channel
EAFICOLK_00356 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EAFICOLK_00357 2e-21 yheA S Belongs to the UPF0342 family
EAFICOLK_00358 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
EAFICOLK_00359 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EAFICOLK_00361 5.4e-53 hit FG histidine triad
EAFICOLK_00362 9.8e-95 ecsA V ABC transporter, ATP-binding protein
EAFICOLK_00363 2.9e-72 ecsB U ABC transporter
EAFICOLK_00364 1e-97 ytmP 2.7.1.89 M Choline/ethanolamine kinase
EAFICOLK_00365 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EAFICOLK_00366 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EAFICOLK_00367 1.2e-75 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EAFICOLK_00368 2.6e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
EAFICOLK_00369 5.8e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EAFICOLK_00370 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
EAFICOLK_00371 1.1e-68 ybhL S Belongs to the BI1 family
EAFICOLK_00372 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EAFICOLK_00373 2.8e-106 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EAFICOLK_00374 2.7e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EAFICOLK_00375 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EAFICOLK_00376 3.3e-80 dnaB L replication initiation and membrane attachment
EAFICOLK_00377 2.2e-107 dnaI L Primosomal protein DnaI
EAFICOLK_00378 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EAFICOLK_00379 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EAFICOLK_00380 3.2e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EAFICOLK_00381 1.7e-52 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EAFICOLK_00382 2.5e-71 yqeG S HAD phosphatase, family IIIA
EAFICOLK_00383 3e-180 yqeH S Ribosome biogenesis GTPase YqeH
EAFICOLK_00384 1e-29 yhbY J RNA-binding protein
EAFICOLK_00385 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EAFICOLK_00386 4.7e-71 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
EAFICOLK_00387 4.3e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EAFICOLK_00388 4.2e-82 H Nodulation protein S (NodS)
EAFICOLK_00389 4.5e-123 ylbM S Belongs to the UPF0348 family
EAFICOLK_00390 2.7e-57 yceD S Uncharacterized ACR, COG1399
EAFICOLK_00391 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EAFICOLK_00392 4e-89 plsC 2.3.1.51 I Acyltransferase
EAFICOLK_00393 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
EAFICOLK_00394 1.5e-27 yazA L GIY-YIG catalytic domain protein
EAFICOLK_00395 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
EAFICOLK_00396 7.9e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EAFICOLK_00397 6.9e-37
EAFICOLK_00398 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
EAFICOLK_00399 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EAFICOLK_00400 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EAFICOLK_00401 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EAFICOLK_00402 1.7e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EAFICOLK_00404 3.1e-111 K response regulator
EAFICOLK_00405 1.3e-167 arlS 2.7.13.3 T Histidine kinase
EAFICOLK_00406 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EAFICOLK_00407 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EAFICOLK_00408 1.8e-135 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
EAFICOLK_00409 7.3e-105
EAFICOLK_00410 5.5e-117
EAFICOLK_00411 1e-41 dut S dUTPase
EAFICOLK_00412 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EAFICOLK_00413 3.7e-46 yqhY S Asp23 family, cell envelope-related function
EAFICOLK_00414 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EAFICOLK_00415 3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EAFICOLK_00416 5.8e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EAFICOLK_00417 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EAFICOLK_00418 8e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EAFICOLK_00419 2.6e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EAFICOLK_00420 6.6e-49 argR K Regulates arginine biosynthesis genes
EAFICOLK_00421 9.3e-178 recN L May be involved in recombinational repair of damaged DNA
EAFICOLK_00422 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EAFICOLK_00423 2.2e-30 ynzC S UPF0291 protein
EAFICOLK_00424 5.9e-27 yneF S UPF0154 protein
EAFICOLK_00425 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
EAFICOLK_00426 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
EAFICOLK_00427 5.5e-75 yciQ P membrane protein (DUF2207)
EAFICOLK_00428 2.3e-19 D nuclear chromosome segregation
EAFICOLK_00429 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EAFICOLK_00430 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EAFICOLK_00431 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
EAFICOLK_00432 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
EAFICOLK_00433 4.7e-158 glk 2.7.1.2 G Glucokinase
EAFICOLK_00434 2.7e-46 yqhL P Rhodanese-like protein
EAFICOLK_00435 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
EAFICOLK_00436 5.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EAFICOLK_00437 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
EAFICOLK_00438 1.3e-45 glnR K Transcriptional regulator
EAFICOLK_00439 2e-247 glnA 6.3.1.2 E glutamine synthetase
EAFICOLK_00441 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EAFICOLK_00442 2.7e-48 S Domain of unknown function (DUF956)
EAFICOLK_00443 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EAFICOLK_00444 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EAFICOLK_00445 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EAFICOLK_00446 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
EAFICOLK_00447 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EAFICOLK_00448 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EAFICOLK_00449 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EAFICOLK_00450 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
EAFICOLK_00451 4.8e-170 nusA K Participates in both transcription termination and antitermination
EAFICOLK_00452 1.4e-39 ylxR K Protein of unknown function (DUF448)
EAFICOLK_00453 6.9e-26 ylxQ J ribosomal protein
EAFICOLK_00454 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EAFICOLK_00455 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EAFICOLK_00456 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EAFICOLK_00457 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EAFICOLK_00458 5.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EAFICOLK_00459 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EAFICOLK_00460 1e-273 dnaK O Heat shock 70 kDa protein
EAFICOLK_00461 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EAFICOLK_00462 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EAFICOLK_00464 1.7e-204 glnP P ABC transporter
EAFICOLK_00465 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EAFICOLK_00466 1.5e-31
EAFICOLK_00467 4.5e-111 ampC V Beta-lactamase
EAFICOLK_00468 7.8e-110 cobQ S glutamine amidotransferase
EAFICOLK_00469 1.8e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
EAFICOLK_00470 6.8e-86 tdk 2.7.1.21 F thymidine kinase
EAFICOLK_00471 1.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EAFICOLK_00472 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EAFICOLK_00473 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EAFICOLK_00474 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EAFICOLK_00475 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
EAFICOLK_00476 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EAFICOLK_00477 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EAFICOLK_00478 2.4e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EAFICOLK_00479 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EAFICOLK_00480 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EAFICOLK_00481 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EAFICOLK_00482 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EAFICOLK_00483 4.1e-15 ywzB S Protein of unknown function (DUF1146)
EAFICOLK_00484 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EAFICOLK_00485 1.2e-167 mbl D Cell shape determining protein MreB Mrl
EAFICOLK_00486 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EAFICOLK_00487 1.3e-13 S Protein of unknown function (DUF2969)
EAFICOLK_00488 6.1e-187 rodA D Belongs to the SEDS family
EAFICOLK_00489 2.1e-26 arsC 1.20.4.1 P Belongs to the ArsC family
EAFICOLK_00490 9.5e-94 2.7.1.89 M Phosphotransferase enzyme family
EAFICOLK_00491 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EAFICOLK_00492 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EAFICOLK_00493 1.4e-119 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EAFICOLK_00494 2.4e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EAFICOLK_00495 1.3e-139 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EAFICOLK_00496 2.6e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EAFICOLK_00497 1.5e-90 stp 3.1.3.16 T phosphatase
EAFICOLK_00498 3e-192 KLT serine threonine protein kinase
EAFICOLK_00499 8.4e-109 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EAFICOLK_00500 5.3e-60 thiN 2.7.6.2 H thiamine pyrophosphokinase
EAFICOLK_00501 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EAFICOLK_00502 4.5e-53 asp S Asp23 family, cell envelope-related function
EAFICOLK_00503 3.3e-239 yloV S DAK2 domain fusion protein YloV
EAFICOLK_00504 5.7e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EAFICOLK_00505 2.7e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EAFICOLK_00506 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAFICOLK_00507 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EAFICOLK_00508 9.7e-209 smc D Required for chromosome condensation and partitioning
EAFICOLK_00509 1e-144 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EAFICOLK_00510 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EAFICOLK_00511 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EAFICOLK_00512 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EAFICOLK_00513 1.1e-26 ylqC S Belongs to the UPF0109 family
EAFICOLK_00514 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EAFICOLK_00515 1.6e-113 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EAFICOLK_00516 4.4e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
EAFICOLK_00517 7e-198 yfnA E amino acid
EAFICOLK_00518 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EAFICOLK_00519 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
EAFICOLK_00520 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EAFICOLK_00521 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAFICOLK_00522 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EAFICOLK_00523 1.8e-18 S Tetratricopeptide repeat
EAFICOLK_00524 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EAFICOLK_00525 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EAFICOLK_00526 3e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EAFICOLK_00527 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EAFICOLK_00528 3.3e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EAFICOLK_00529 2.5e-22 ykzG S Belongs to the UPF0356 family
EAFICOLK_00530 5.5e-25
EAFICOLK_00531 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EAFICOLK_00532 1.8e-31 1.1.1.27 C L-malate dehydrogenase activity
EAFICOLK_00533 1.7e-23 yktA S Belongs to the UPF0223 family
EAFICOLK_00534 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EAFICOLK_00535 0.0 typA T GTP-binding protein TypA
EAFICOLK_00536 1e-147 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
EAFICOLK_00537 7e-115 manY G PTS system
EAFICOLK_00538 6.6e-149 manN G system, mannose fructose sorbose family IID component
EAFICOLK_00539 3e-101 ftsW D Belongs to the SEDS family
EAFICOLK_00540 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EAFICOLK_00541 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
EAFICOLK_00542 1.6e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
EAFICOLK_00543 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EAFICOLK_00544 2.4e-131 ylbL T Belongs to the peptidase S16 family
EAFICOLK_00545 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EAFICOLK_00546 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAFICOLK_00547 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAFICOLK_00548 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAFICOLK_00549 5.5e-227 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EAFICOLK_00550 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EAFICOLK_00551 1.2e-74 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EAFICOLK_00552 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EAFICOLK_00553 5.4e-162 purD 6.3.4.13 F Belongs to the GARS family
EAFICOLK_00554 1.3e-108 S Acyltransferase family
EAFICOLK_00555 2e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAFICOLK_00556 8.6e-122 K LysR substrate binding domain
EAFICOLK_00558 2.2e-20
EAFICOLK_00559 2.3e-58 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EAFICOLK_00560 5.8e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
EAFICOLK_00561 6.8e-50 comEA L Competence protein ComEA
EAFICOLK_00562 2e-69 comEB 3.5.4.12 F ComE operon protein 2
EAFICOLK_00563 4.7e-156 comEC S Competence protein ComEC
EAFICOLK_00564 2.7e-103 holA 2.7.7.7 L DNA polymerase III delta subunit
EAFICOLK_00565 5.6e-112 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EAFICOLK_00566 2.5e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
EAFICOLK_00567 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EAFICOLK_00568 8.1e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EAFICOLK_00569 8.2e-227 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EAFICOLK_00570 1.4e-36 ypmB S Protein conserved in bacteria
EAFICOLK_00571 3.1e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EAFICOLK_00572 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
EAFICOLK_00573 5.1e-56 dnaD L DnaD domain protein
EAFICOLK_00574 1.5e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EAFICOLK_00575 2.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EAFICOLK_00576 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EAFICOLK_00577 4.7e-92 M transferase activity, transferring glycosyl groups
EAFICOLK_00578 3.7e-84 M Glycosyltransferase sugar-binding region containing DXD motif
EAFICOLK_00579 5.8e-100 epsJ1 M Glycosyltransferase like family 2
EAFICOLK_00582 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EAFICOLK_00583 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EAFICOLK_00584 1.8e-56 yqeY S YqeY-like protein
EAFICOLK_00586 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
EAFICOLK_00587 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EAFICOLK_00588 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EAFICOLK_00589 6.6e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EAFICOLK_00590 1.4e-275 yfmR S ABC transporter, ATP-binding protein
EAFICOLK_00591 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EAFICOLK_00592 3.2e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EAFICOLK_00593 8.6e-135 yvgN C Aldo keto reductase
EAFICOLK_00594 9.2e-35 K helix_turn_helix, mercury resistance
EAFICOLK_00595 7.7e-64 S Aldo keto reductase
EAFICOLK_00596 1.1e-42 S Aldo keto reductase
EAFICOLK_00598 6.5e-80 ypmR E GDSL-like Lipase/Acylhydrolase
EAFICOLK_00599 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
EAFICOLK_00600 6.2e-24 yozE S Belongs to the UPF0346 family
EAFICOLK_00601 1e-132 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EAFICOLK_00602 6.3e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EAFICOLK_00603 4e-84 dprA LU DNA protecting protein DprA
EAFICOLK_00604 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAFICOLK_00605 2.8e-209 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EAFICOLK_00606 2.2e-204 G PTS system Galactitol-specific IIC component
EAFICOLK_00607 2.1e-153 M Exporter of polyketide antibiotics
EAFICOLK_00608 8.5e-34 cas6 S Pfam:DUF2276
EAFICOLK_00609 1.7e-209 csm1 S CRISPR-associated protein Csm1 family
EAFICOLK_00610 2.8e-33 csm2 L Csm2 Type III-A
EAFICOLK_00611 2.6e-70 csm3 L RAMP superfamily
EAFICOLK_00612 4e-66 csm4 L CRISPR-associated RAMP protein, Csm4 family
EAFICOLK_00613 2.9e-70 csm5 L RAMP superfamily
EAFICOLK_00614 1.3e-88 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EAFICOLK_00615 4.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EAFICOLK_00616 1.1e-71 csm6 S Psort location Cytoplasmic, score
EAFICOLK_00617 1.1e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
EAFICOLK_00618 2.7e-35 S Repeat protein
EAFICOLK_00619 3.4e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EAFICOLK_00621 1.7e-15
EAFICOLK_00622 6.2e-68 M Peptidase family M23
EAFICOLK_00623 4.8e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EAFICOLK_00624 2.4e-92 M Core-2/I-Branching enzyme
EAFICOLK_00625 2.4e-75 waaB GT4 M Glycosyl transferases group 1
EAFICOLK_00626 2.6e-93 M transferase activity, transferring glycosyl groups
EAFICOLK_00627 1.1e-57 cps3F
EAFICOLK_00628 1.1e-73 M LicD family
EAFICOLK_00629 1.9e-63 M Glycosyltransferase like family 2
EAFICOLK_00630 2.5e-109 S Psort location CytoplasmicMembrane, score
EAFICOLK_00631 1.9e-195 glf 5.4.99.9 M UDP-galactopyranose mutase
EAFICOLK_00632 5.5e-61 S Glycosyltransferase like family 2
EAFICOLK_00633 2.4e-153 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
EAFICOLK_00635 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EAFICOLK_00636 1.8e-159 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EAFICOLK_00637 2.1e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EAFICOLK_00638 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
EAFICOLK_00639 4.1e-157 XK27_09615 S reductase
EAFICOLK_00640 6.8e-40 2.7.7.65 T phosphorelay sensor kinase activity
EAFICOLK_00641 6.6e-147 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EAFICOLK_00642 3.1e-54 cps3I G Acyltransferase family
EAFICOLK_00643 3.6e-14
EAFICOLK_00644 4.5e-159 XK27_08315 M Sulfatase
EAFICOLK_00645 3e-175 thrC 4.2.3.1 E Threonine synthase
EAFICOLK_00646 3.4e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EAFICOLK_00647 5.2e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EAFICOLK_00648 1.2e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EAFICOLK_00649 5.7e-178 licA 2.7.1.89 M Choline/ethanolamine kinase
EAFICOLK_00650 1.9e-84 M Nucleotidyl transferase
EAFICOLK_00651 2e-150 M Belongs to the BCCT transporter (TC 2.A.15) family
EAFICOLK_00652 9e-57 S peptidoglycan catabolic process
EAFICOLK_00653 2.8e-193 XK27_08315 M Sulfatase
EAFICOLK_00655 6.4e-168 mdtG EGP Major facilitator Superfamily
EAFICOLK_00656 4.4e-252 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
EAFICOLK_00657 5.7e-84 treR K UTRA
EAFICOLK_00658 9.5e-259 treB G phosphotransferase system
EAFICOLK_00659 1.6e-63 3.1.3.73 G phosphoglycerate mutase
EAFICOLK_00660 2.4e-82 pncA Q isochorismatase
EAFICOLK_00661 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
EAFICOLK_00662 1.2e-103 ydhQ K UbiC transcription regulator-associated domain protein
EAFICOLK_00663 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EAFICOLK_00664 3.6e-41 K Transcriptional regulator, HxlR family
EAFICOLK_00665 3.7e-164 C Luciferase-like monooxygenase
EAFICOLK_00666 6.6e-67 1.5.1.38 S NADPH-dependent FMN reductase
EAFICOLK_00667 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EAFICOLK_00668 2.6e-75 L haloacid dehalogenase-like hydrolase
EAFICOLK_00669 4e-61 EG EamA-like transporter family
EAFICOLK_00670 5.3e-118 K AI-2E family transporter
EAFICOLK_00671 2.2e-173 malY 4.4.1.8 E Aminotransferase, class I
EAFICOLK_00672 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EAFICOLK_00673 7.8e-60 yfjR K WYL domain
EAFICOLK_00674 1.8e-11 S Mor transcription activator family
EAFICOLK_00675 9.5e-10 S zinc-ribbon domain
EAFICOLK_00676 3.4e-41 S Protein of unknown function (DUF1211)
EAFICOLK_00677 2.8e-26 ybl78 L Conserved phage C-terminus (Phg_2220_C)
EAFICOLK_00679 3.3e-41 wecD M Acetyltransferase (GNAT) family
EAFICOLK_00680 3.5e-76 cps2D 5.1.3.2 M RmlD substrate binding domain
EAFICOLK_00681 8.6e-67 H Methyltransferase domain
EAFICOLK_00683 3.7e-16 K DNA-templated transcription, initiation
EAFICOLK_00685 2.2e-08 S Protein of unknown function (DUF2922)
EAFICOLK_00687 8.6e-147 scrR K helix_turn _helix lactose operon repressor
EAFICOLK_00688 5.3e-217 scrB 3.2.1.26 GH32 G invertase
EAFICOLK_00689 2.3e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
EAFICOLK_00690 5.3e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
EAFICOLK_00691 1.2e-114 ntpJ P Potassium uptake protein
EAFICOLK_00692 2.8e-58 ktrA P TrkA-N domain
EAFICOLK_00693 7.4e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
EAFICOLK_00694 4.4e-37 M Glycosyltransferase group 2 family protein
EAFICOLK_00695 1.4e-19
EAFICOLK_00696 1.4e-94 S Predicted membrane protein (DUF2207)
EAFICOLK_00697 2.1e-54 bioY S BioY family
EAFICOLK_00698 1.7e-183 lmrB EGP Major facilitator Superfamily
EAFICOLK_00699 2e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EAFICOLK_00700 7.6e-74 glcR K DeoR C terminal sensor domain
EAFICOLK_00701 4.5e-61 yceE S haloacid dehalogenase-like hydrolase
EAFICOLK_00702 2.5e-41 S CAAX protease self-immunity
EAFICOLK_00703 7e-34 S Domain of unknown function (DUF4811)
EAFICOLK_00704 2.1e-197 lmrB EGP Major facilitator Superfamily
EAFICOLK_00705 1.9e-32 merR K MerR HTH family regulatory protein
EAFICOLK_00706 1e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EAFICOLK_00707 1.6e-70 S Protein of unknown function (DUF554)
EAFICOLK_00708 2.4e-120 G Bacterial extracellular solute-binding protein
EAFICOLK_00709 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
EAFICOLK_00710 3e-99 baeS T Histidine kinase
EAFICOLK_00711 1.8e-80 rbsB G sugar-binding domain protein
EAFICOLK_00712 1.2e-151 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
EAFICOLK_00713 6.4e-116 manY G PTS system sorbose-specific iic component
EAFICOLK_00714 2.1e-147 manN G system, mannose fructose sorbose family IID component
EAFICOLK_00715 4.1e-52 manO S Domain of unknown function (DUF956)
EAFICOLK_00716 3.5e-70 mltD CBM50 M NlpC P60 family protein
EAFICOLK_00717 1.1e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EAFICOLK_00718 2.4e-164 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAFICOLK_00719 4.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
EAFICOLK_00720 1.8e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EAFICOLK_00721 8.1e-38 K transcriptional regulator PadR family
EAFICOLK_00722 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
EAFICOLK_00723 2.4e-16 S Putative adhesin
EAFICOLK_00724 2.2e-16 pspC KT PspC domain
EAFICOLK_00726 3.9e-13 S Enterocin A Immunity
EAFICOLK_00727 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EAFICOLK_00728 3.7e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
EAFICOLK_00729 4.8e-99 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EAFICOLK_00730 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EAFICOLK_00731 7.3e-120 potB P ABC transporter permease
EAFICOLK_00732 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
EAFICOLK_00733 1.3e-159 potD P ABC transporter
EAFICOLK_00734 3.5e-132 ABC-SBP S ABC transporter
EAFICOLK_00735 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
EAFICOLK_00736 2.7e-108 XK27_08845 S ABC transporter, ATP-binding protein
EAFICOLK_00737 1.5e-67 M ErfK YbiS YcfS YnhG
EAFICOLK_00738 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EAFICOLK_00739 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EAFICOLK_00740 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EAFICOLK_00741 1.2e-102 pgm3 G phosphoglycerate mutase
EAFICOLK_00742 8.5e-58 S CAAX protease self-immunity
EAFICOLK_00743 2.2e-47 C Flavodoxin
EAFICOLK_00744 3.1e-58 yphH S Cupin domain
EAFICOLK_00745 1e-45 yphJ 4.1.1.44 S decarboxylase
EAFICOLK_00747 2.6e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EAFICOLK_00748 3.3e-165 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EAFICOLK_00749 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EAFICOLK_00750 2.1e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EAFICOLK_00751 5.9e-91 rfbP M Bacterial sugar transferase
EAFICOLK_00752 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EAFICOLK_00753 1.6e-111 ywqE 3.1.3.48 GM PHP domain protein
EAFICOLK_00754 2.1e-81 ywqD 2.7.10.1 D Capsular exopolysaccharide family
EAFICOLK_00755 2.3e-73 epsB M biosynthesis protein
EAFICOLK_00757 1.3e-49 M group 2 family protein
EAFICOLK_00758 2.8e-52 M Psort location Cytoplasmic, score
EAFICOLK_00759 1.3e-38
EAFICOLK_00760 5e-52 M LicD family
EAFICOLK_00761 1.3e-105 4.2.1.46 GM Male sterility protein
EAFICOLK_00762 2.7e-97 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
EAFICOLK_00763 1.7e-97 M Glycosyl transferase family 8
EAFICOLK_00764 2.2e-15 S zinc-ribbon domain
EAFICOLK_00765 2.2e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EAFICOLK_00766 4.6e-134 coaA 2.7.1.33 F Pantothenic acid kinase
EAFICOLK_00767 4.2e-40 E lipolytic protein G-D-S-L family
EAFICOLK_00768 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EAFICOLK_00769 5.6e-190 glnPH2 P ABC transporter permease
EAFICOLK_00770 1.6e-213 yjeM E Amino Acid
EAFICOLK_00771 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
EAFICOLK_00772 3e-138 tetA EGP Major facilitator Superfamily
EAFICOLK_00773 5e-62 S Glycosyltransferase like family 2
EAFICOLK_00774 5.3e-118 cps1D M Domain of unknown function (DUF4422)
EAFICOLK_00775 3e-39 S CAAX protease self-immunity
EAFICOLK_00776 9.1e-89 yvyE 3.4.13.9 S YigZ family
EAFICOLK_00777 1.9e-57 S Haloacid dehalogenase-like hydrolase
EAFICOLK_00778 3.4e-154 EGP Major facilitator Superfamily
EAFICOLK_00780 1.5e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
EAFICOLK_00781 2.1e-27 yraB K transcriptional regulator
EAFICOLK_00782 9.8e-90 S NADPH-dependent FMN reductase
EAFICOLK_00783 2e-101 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EAFICOLK_00784 1.5e-55 S ECF transporter, substrate-specific component
EAFICOLK_00785 3.3e-96 znuB U ABC 3 transport family
EAFICOLK_00786 2.6e-99 fhuC P ABC transporter
EAFICOLK_00787 1.3e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
EAFICOLK_00788 1.5e-38
EAFICOLK_00789 1.2e-52 XK27_01040 S Protein of unknown function (DUF1129)
EAFICOLK_00790 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EAFICOLK_00791 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
EAFICOLK_00792 4.1e-108 spo0J K Belongs to the ParB family
EAFICOLK_00793 6.5e-118 soj D Sporulation initiation inhibitor
EAFICOLK_00794 3.7e-82 noc K Belongs to the ParB family
EAFICOLK_00795 6.2e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
EAFICOLK_00796 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EAFICOLK_00797 1.4e-109 3.1.4.46 C phosphodiesterase
EAFICOLK_00798 0.0 pacL 3.6.3.8 P P-type ATPase
EAFICOLK_00801 4.1e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
EAFICOLK_00802 1e-27 ysxB J Cysteine protease Prp
EAFICOLK_00803 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EAFICOLK_00804 3.7e-12
EAFICOLK_00806 4.8e-72
EAFICOLK_00807 5.9e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
EAFICOLK_00808 2.7e-179 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
EAFICOLK_00809 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
EAFICOLK_00810 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EAFICOLK_00811 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EAFICOLK_00812 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EAFICOLK_00813 1.6e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EAFICOLK_00814 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EAFICOLK_00815 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EAFICOLK_00816 3.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EAFICOLK_00817 4.1e-51 yeaL S Protein of unknown function (DUF441)
EAFICOLK_00818 2.8e-125 cvfB S S1 domain
EAFICOLK_00819 1.6e-112 xerD D recombinase XerD
EAFICOLK_00820 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
EAFICOLK_00821 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EAFICOLK_00822 8.3e-188 nhaC C Na H antiporter NhaC
EAFICOLK_00823 1.3e-64 ypsA S Belongs to the UPF0398 family
EAFICOLK_00824 4.6e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
EAFICOLK_00825 1e-08 D Antitoxin Phd_YefM, type II toxin-antitoxin system
EAFICOLK_00826 3.9e-08 XK27_10540 S ParE toxin of type II toxin-antitoxin system, parDE
EAFICOLK_00828 2.8e-73 2.3.1.178 M GNAT acetyltransferase
EAFICOLK_00829 1.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
EAFICOLK_00830 5.7e-57 3.6.1.27 I Acid phosphatase homologues
EAFICOLK_00831 6.2e-65
EAFICOLK_00832 1.2e-14 hsdM 2.1.1.72 V type I restriction-modification system
EAFICOLK_00833 2.7e-15 K Cro/C1-type HTH DNA-binding domain
EAFICOLK_00834 0.0 L helicase superfamily c-terminal domain
EAFICOLK_00835 1.4e-98 S Domain of unknown function (DUF4391)
EAFICOLK_00836 1.2e-151 mod 2.1.1.72 L PFAM DNA methylase N-4 N-6 domain protein
EAFICOLK_00839 3.8e-191 mod 2.1.1.72 L DNA methylase
EAFICOLK_00840 0.0 res 3.1.21.5 L Type III restriction enzyme, res subunit
EAFICOLK_00841 8.3e-15 E Zn peptidase
EAFICOLK_00842 1.4e-76 E Zn peptidase
EAFICOLK_00843 1.9e-80 XK27_07525 3.6.1.55 F Hydrolase, nudix family
EAFICOLK_00845 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
EAFICOLK_00846 4e-202 hsdM 2.1.1.72 V type I restriction-modification system
EAFICOLK_00847 2.1e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EAFICOLK_00848 7.2e-243 lysP E amino acid
EAFICOLK_00849 2.3e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
EAFICOLK_00850 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EAFICOLK_00851 9.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAFICOLK_00852 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
EAFICOLK_00853 7.6e-83 lysR5 K LysR substrate binding domain
EAFICOLK_00854 2.2e-119 yxaA S membrane transporter protein
EAFICOLK_00855 2.6e-32 ywjH S Protein of unknown function (DUF1634)
EAFICOLK_00856 3.2e-118 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EAFICOLK_00857 1.6e-226 pipD E Dipeptidase
EAFICOLK_00858 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
EAFICOLK_00859 1.5e-165 EGP Major facilitator Superfamily
EAFICOLK_00860 4.7e-81 S L,D-transpeptidase catalytic domain
EAFICOLK_00861 9.6e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EAFICOLK_00862 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EAFICOLK_00863 7.5e-27 ydiI Q Thioesterase superfamily
EAFICOLK_00864 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
EAFICOLK_00865 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
EAFICOLK_00866 6.4e-114 degV S EDD domain protein, DegV family
EAFICOLK_00867 1e-225 cadA P P-type ATPase
EAFICOLK_00868 1.8e-254 E Amino acid permease
EAFICOLK_00869 2.1e-83 S Membrane
EAFICOLK_00870 4.5e-49 cps3F
EAFICOLK_00871 2.1e-282 fruA 2.7.1.202 GT Phosphotransferase System
EAFICOLK_00872 9.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EAFICOLK_00873 4.5e-87 fruR K DeoR C terminal sensor domain
EAFICOLK_00874 6.7e-219 XK27_08635 S UPF0210 protein
EAFICOLK_00875 1.1e-27 gcvR T Belongs to the UPF0237 family
EAFICOLK_00876 1.8e-38
EAFICOLK_00877 6.3e-77 E GDSL-like Lipase/Acylhydrolase family
EAFICOLK_00878 9.2e-56 S Protein of unknown function (DUF975)
EAFICOLK_00879 4.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
EAFICOLK_00880 4e-230 lpdA 1.8.1.4 C Dehydrogenase
EAFICOLK_00881 5.9e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EAFICOLK_00882 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
EAFICOLK_00883 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EAFICOLK_00886 4.2e-58 S Protein of unknown function (DUF4256)
EAFICOLK_00887 5.6e-128 metQ M Belongs to the nlpA lipoprotein family
EAFICOLK_00888 1.2e-30 metI U ABC transporter permease
EAFICOLK_00889 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAFICOLK_00892 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
EAFICOLK_00893 2.7e-30 S CHY zinc finger
EAFICOLK_00894 2.1e-39 K Transcriptional regulator
EAFICOLK_00895 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
EAFICOLK_00897 1.6e-43 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
EAFICOLK_00898 2.2e-180 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EAFICOLK_00899 4.8e-81
EAFICOLK_00900 6.2e-84 yjfP S COG1073 Hydrolases of the alpha beta superfamily
EAFICOLK_00901 1e-113 yitU 3.1.3.104 S hydrolase
EAFICOLK_00902 5.6e-60 speG J Acetyltransferase (GNAT) domain
EAFICOLK_00903 4.8e-190 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EAFICOLK_00904 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EAFICOLK_00905 4.5e-205 pipD E Dipeptidase
EAFICOLK_00906 9.5e-44
EAFICOLK_00907 9.1e-65 K helix_turn_helix, arabinose operon control protein
EAFICOLK_00908 1.5e-53 S Membrane
EAFICOLK_00909 0.0 rafA 3.2.1.22 G alpha-galactosidase
EAFICOLK_00910 2.6e-58 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
EAFICOLK_00911 3.8e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
EAFICOLK_00912 1.9e-113 2.7.7.65 T diguanylate cyclase activity
EAFICOLK_00913 0.0 ydaN S Bacterial cellulose synthase subunit
EAFICOLK_00914 6.9e-202 ydaM M Glycosyl transferase family group 2
EAFICOLK_00915 5.8e-206 S Protein conserved in bacteria
EAFICOLK_00916 2.6e-184
EAFICOLK_00917 6.6e-129 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
EAFICOLK_00918 7.3e-44 2.7.7.65 T GGDEF domain
EAFICOLK_00919 1.9e-146 pbuO_1 S Permease family
EAFICOLK_00920 8.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
EAFICOLK_00921 4.8e-104 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
EAFICOLK_00922 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EAFICOLK_00923 3.6e-220 cydD CO ABC transporter transmembrane region
EAFICOLK_00924 3.5e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EAFICOLK_00925 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
EAFICOLK_00926 2.1e-194 cydA 1.10.3.14 C ubiquinol oxidase
EAFICOLK_00927 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
EAFICOLK_00928 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
EAFICOLK_00929 5e-19 glpE P Rhodanese Homology Domain
EAFICOLK_00930 2.9e-49 lytE M LysM domain protein
EAFICOLK_00931 1.6e-93 T Calcineurin-like phosphoesterase superfamily domain
EAFICOLK_00932 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
EAFICOLK_00934 1e-39 ypaA S Protein of unknown function (DUF1304)
EAFICOLK_00935 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EAFICOLK_00936 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EAFICOLK_00937 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EAFICOLK_00938 1.9e-202 FbpA K Fibronectin-binding protein
EAFICOLK_00939 3.1e-40 K Transcriptional regulator
EAFICOLK_00940 1.8e-116 degV S EDD domain protein, DegV family
EAFICOLK_00941 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
EAFICOLK_00942 5.5e-40 6.3.3.2 S ASCH
EAFICOLK_00943 2.2e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EAFICOLK_00944 3.8e-79 yjjH S Calcineurin-like phosphoesterase
EAFICOLK_00945 1.8e-95 EG EamA-like transporter family
EAFICOLK_00946 8.1e-83 natB CP ABC-type Na efflux pump, permease component
EAFICOLK_00947 2.8e-112 natA S Domain of unknown function (DUF4162)
EAFICOLK_00948 3.7e-23 K Acetyltransferase (GNAT) domain
EAFICOLK_00949 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EAFICOLK_00950 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EAFICOLK_00951 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
EAFICOLK_00952 1.4e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
EAFICOLK_00953 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EAFICOLK_00954 1.4e-28 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EAFICOLK_00955 1.2e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
EAFICOLK_00956 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EAFICOLK_00957 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
EAFICOLK_00958 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
EAFICOLK_00959 1e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EAFICOLK_00960 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EAFICOLK_00961 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EAFICOLK_00962 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
EAFICOLK_00963 2.6e-83 lytH 3.5.1.28 M Ami_3
EAFICOLK_00964 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EAFICOLK_00965 7.7e-12 M Lysin motif
EAFICOLK_00966 2.2e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
EAFICOLK_00967 9.9e-61 ypbB 5.1.3.1 S Helix-turn-helix domain
EAFICOLK_00968 6.4e-221 mntH P H( )-stimulated, divalent metal cation uptake system
EAFICOLK_00969 1.3e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EAFICOLK_00970 6.9e-214 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EAFICOLK_00971 3.9e-282 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EAFICOLK_00972 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EAFICOLK_00973 5.8e-110 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
EAFICOLK_00974 2.2e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EAFICOLK_00978 4e-108 D Psort location Cytoplasmic, score
EAFICOLK_00980 2e-44 recT L RecT family
EAFICOLK_00981 2e-49 S Metallo-beta-lactamase superfamily
EAFICOLK_00982 1.8e-75 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
EAFICOLK_00983 1.5e-37
EAFICOLK_00985 2.4e-20 S dCTP diphosphatase activity
EAFICOLK_00986 5.5e-38
EAFICOLK_00988 8.9e-42 ssb L COG COG0629 Single-stranded DNA-binding protein
EAFICOLK_00989 1.8e-42 L Phage replisome organizer N-terminal
EAFICOLK_00992 1.1e-24
EAFICOLK_00994 4.8e-14
EAFICOLK_00995 1.6e-46 xtmA L Terminase small subunit
EAFICOLK_00996 5.4e-195 S TIGRFAM Phage
EAFICOLK_00997 6.4e-16 S Psort location Cytoplasmic, score
EAFICOLK_00998 2.1e-120 S Phage portal protein, SPP1 Gp6-like
EAFICOLK_00999 1.6e-100 S Phage Mu protein F like protein
EAFICOLK_01002 3.1e-20
EAFICOLK_01003 1.3e-26 S tail collar domain protein
EAFICOLK_01006 2.4e-27 S Phage minor structural protein GP20
EAFICOLK_01007 4.5e-102 S Psort location Cytoplasmic, score
EAFICOLK_01008 7e-20
EAFICOLK_01009 4e-25
EAFICOLK_01010 6.9e-29 S Bacteriophage HK97-gp10, putative tail-component
EAFICOLK_01011 1.7e-22
EAFICOLK_01013 2.4e-141 xkdK S Phage tail sheath protein beta-sandwich domain
EAFICOLK_01014 3.5e-61 xkdM S Phage tail tube protein
EAFICOLK_01015 1.2e-44 S Phage XkdN-like tail assembly chaperone protein, TAC
EAFICOLK_01016 9.6e-128
EAFICOLK_01017 6.7e-64 ygaU S LysM domain
EAFICOLK_01018 1.6e-105 G PFAM Phage late control gene D protein (GPD)
EAFICOLK_01019 3.1e-20 S Protein of unknown function (DUF2577)
EAFICOLK_01020 3.1e-34 S Protein of unknown function (DUF2634)
EAFICOLK_01021 2.1e-106 xkdT S Baseplate J-like protein
EAFICOLK_01022 1.7e-25 S Uncharacterised protein conserved in bacteria (DUF2313)
EAFICOLK_01023 9.3e-19 S Putative phage holin Dp-1
EAFICOLK_01025 2.6e-41 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EAFICOLK_01026 6e-10
EAFICOLK_01027 4.8e-19 S Predicted membrane protein (DUF2335)
EAFICOLK_01028 2.8e-24 fdx 1.12.98.1 C electron transfer activity
EAFICOLK_01029 7.5e-208 L Belongs to the 'phage' integrase family
EAFICOLK_01030 6.1e-205 D T5orf172
EAFICOLK_01031 1.3e-47
EAFICOLK_01032 3.3e-33 K Helix-turn-helix XRE-family like proteins
EAFICOLK_01033 3.4e-08 S Helix-turn-helix domain of resolvase
EAFICOLK_01039 4.6e-57 S Phage regulatory protein Rha (Phage_pRha)
EAFICOLK_01040 1.7e-89 3.1.21.3 V Type I restriction modification DNA specificity domain
EAFICOLK_01041 3.6e-131 L Belongs to the 'phage' integrase family
EAFICOLK_01042 1.7e-73 3.1.21.3 V Type I restriction modification DNA specificity domain
EAFICOLK_01043 8.3e-15 O ADP-ribosylglycohydrolase
EAFICOLK_01044 3.2e-45 yjcF K protein acetylation
EAFICOLK_01046 3.7e-252 yfiC V ABC transporter
EAFICOLK_01047 2.6e-223 lmrA V ABC transporter, ATP-binding protein
EAFICOLK_01048 4.5e-35 K Bacterial regulatory proteins, tetR family
EAFICOLK_01049 9.5e-246 yhcA V ABC transporter, ATP-binding protein
EAFICOLK_01050 2.6e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EAFICOLK_01051 1e-146 G Transporter, major facilitator family protein
EAFICOLK_01052 5.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
EAFICOLK_01053 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
EAFICOLK_01054 2.5e-113 K response regulator
EAFICOLK_01055 3.4e-89 patB 4.4.1.8 E Aminotransferase, class I
EAFICOLK_01056 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EAFICOLK_01057 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EAFICOLK_01058 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EAFICOLK_01059 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EAFICOLK_01060 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
EAFICOLK_01061 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EAFICOLK_01062 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EAFICOLK_01063 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EAFICOLK_01064 1.6e-55 ctsR K Belongs to the CtsR family
EAFICOLK_01066 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EAFICOLK_01067 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EAFICOLK_01068 6.3e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EAFICOLK_01069 3.2e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EAFICOLK_01070 3.7e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EAFICOLK_01076 1e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EAFICOLK_01077 6.1e-39
EAFICOLK_01080 1.3e-17 D nuclear chromosome segregation
EAFICOLK_01083 9.6e-149 EGP Sugar (and other) transporter
EAFICOLK_01084 7.1e-79 trmK 2.1.1.217 S SAM-dependent methyltransferase
EAFICOLK_01085 2.8e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EAFICOLK_01086 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EAFICOLK_01087 4.2e-73 alkD L DNA alkylation repair enzyme
EAFICOLK_01088 3.8e-136 EG EamA-like transporter family
EAFICOLK_01089 3.1e-149 S Tetratricopeptide repeat protein
EAFICOLK_01090 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
EAFICOLK_01091 3.6e-297 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EAFICOLK_01092 7e-127 corA P CorA-like Mg2+ transporter protein
EAFICOLK_01093 8.5e-161 nhaC C Na H antiporter NhaC
EAFICOLK_01094 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EAFICOLK_01095 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
EAFICOLK_01097 2.5e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAFICOLK_01098 1.3e-159 iscS 2.8.1.7 E Aminotransferase class V
EAFICOLK_01099 3.7e-41 XK27_04120 S Putative amino acid metabolism
EAFICOLK_01100 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EAFICOLK_01101 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EAFICOLK_01102 4.3e-15 S Protein of unknown function (DUF2929)
EAFICOLK_01103 0.0 dnaE 2.7.7.7 L DNA polymerase
EAFICOLK_01104 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EAFICOLK_01105 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EAFICOLK_01106 8.8e-50 yugI 5.3.1.9 J general stress protein
EAFICOLK_01107 9.4e-96 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EAFICOLK_01108 5.1e-92 dedA S SNARE associated Golgi protein
EAFICOLK_01109 7.8e-32 S Protein of unknown function (DUF1461)
EAFICOLK_01110 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EAFICOLK_01111 1.9e-53 yutD S Protein of unknown function (DUF1027)
EAFICOLK_01112 3e-57 S Calcineurin-like phosphoesterase
EAFICOLK_01113 1.6e-183 cycA E Amino acid permease
EAFICOLK_01114 1.2e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
EAFICOLK_01116 7.2e-11 S Putative Competence protein ComGF
EAFICOLK_01118 1.5e-13
EAFICOLK_01119 1.2e-27 comGC U competence protein ComGC
EAFICOLK_01120 5.7e-98 comGB NU type II secretion system
EAFICOLK_01121 3.1e-120 comGA NU Type II IV secretion system protein
EAFICOLK_01122 7.9e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAFICOLK_01123 1.5e-119 yebC K Transcriptional regulatory protein
EAFICOLK_01124 4.8e-42 S VanZ like family
EAFICOLK_01125 1.3e-158 ccpA K catabolite control protein A
EAFICOLK_01126 1.1e-171 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EAFICOLK_01127 3e-14
EAFICOLK_01130 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EAFICOLK_01131 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
EAFICOLK_01132 5.2e-65 hly S protein, hemolysin III
EAFICOLK_01133 7.3e-41 M1-874 K Domain of unknown function (DUF1836)
EAFICOLK_01134 9.4e-84 S membrane
EAFICOLK_01135 1.1e-79 S VIT family
EAFICOLK_01136 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
EAFICOLK_01137 2.7e-56 P Plays a role in the regulation of phosphate uptake
EAFICOLK_01138 2.3e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EAFICOLK_01139 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EAFICOLK_01140 5.1e-122 pstA P Phosphate transport system permease protein PstA
EAFICOLK_01141 7e-119 pstC P probably responsible for the translocation of the substrate across the membrane
EAFICOLK_01142 6.4e-90 pstS P Phosphate
EAFICOLK_01143 1.3e-41 yjbH Q Thioredoxin
EAFICOLK_01144 4.3e-232 pepF E oligoendopeptidase F
EAFICOLK_01145 1.9e-68 coiA 3.6.4.12 S Competence protein
EAFICOLK_01146 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EAFICOLK_01147 1.4e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
EAFICOLK_01151 2.2e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAFICOLK_01152 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
EAFICOLK_01153 9.1e-43 yodB K Transcriptional regulator, HxlR family
EAFICOLK_01154 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EAFICOLK_01155 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EAFICOLK_01156 1.8e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EAFICOLK_01157 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
EAFICOLK_01158 6.5e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EAFICOLK_01159 6.4e-12
EAFICOLK_01160 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
EAFICOLK_01161 2e-43 XK27_03960 S Protein of unknown function (DUF3013)
EAFICOLK_01162 5.8e-118 prmA J Ribosomal protein L11 methyltransferase
EAFICOLK_01163 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EAFICOLK_01164 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAFICOLK_01165 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EAFICOLK_01166 6.7e-57 3.1.3.18 J HAD-hyrolase-like
EAFICOLK_01167 4.4e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EAFICOLK_01168 5.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EAFICOLK_01169 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EAFICOLK_01170 2.7e-204 pyrP F Permease
EAFICOLK_01171 3.7e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EAFICOLK_01172 2.9e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EAFICOLK_01173 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EAFICOLK_01174 7.4e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EAFICOLK_01175 4.7e-134 K Transcriptional regulator
EAFICOLK_01176 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
EAFICOLK_01177 3.9e-115 glcR K DeoR C terminal sensor domain
EAFICOLK_01178 1.3e-170 patA 2.6.1.1 E Aminotransferase
EAFICOLK_01179 3.2e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EAFICOLK_01181 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EAFICOLK_01182 1.6e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EAFICOLK_01183 3.1e-36 rnhA 3.1.26.4 L Ribonuclease HI
EAFICOLK_01184 5e-23 S Family of unknown function (DUF5322)
EAFICOLK_01185 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EAFICOLK_01186 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
EAFICOLK_01187 2.6e-130 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EAFICOLK_01188 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
EAFICOLK_01189 2e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EAFICOLK_01190 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAFICOLK_01191 9.7e-37 ptsH G phosphocarrier protein HPR
EAFICOLK_01192 1.5e-15
EAFICOLK_01193 0.0 clpE O Belongs to the ClpA ClpB family
EAFICOLK_01194 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
EAFICOLK_01195 1.1e-104 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
EAFICOLK_01196 0.0 rafA 3.2.1.22 G alpha-galactosidase
EAFICOLK_01197 1.2e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EAFICOLK_01198 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EAFICOLK_01199 2e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EAFICOLK_01200 4.5e-111 galR K Transcriptional regulator
EAFICOLK_01201 8.9e-289 lacS G Transporter
EAFICOLK_01202 0.0 lacL 3.2.1.23 G -beta-galactosidase
EAFICOLK_01203 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EAFICOLK_01204 1e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EAFICOLK_01205 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EAFICOLK_01206 6.9e-92 yueF S AI-2E family transporter
EAFICOLK_01207 2.6e-97 ygaC J Belongs to the UPF0374 family
EAFICOLK_01208 1.4e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAFICOLK_01209 7.6e-69 recX 2.4.1.337 GT4 S Regulatory protein RecX
EAFICOLK_01210 2.3e-19 sigH K DNA-templated transcription, initiation
EAFICOLK_01211 1.6e-22 S Cytochrome B5
EAFICOLK_01212 3.9e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
EAFICOLK_01213 7.6e-60
EAFICOLK_01214 3.7e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EAFICOLK_01215 8.6e-156 nrnB S DHHA1 domain
EAFICOLK_01216 2.5e-91 yunF F Protein of unknown function DUF72
EAFICOLK_01217 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
EAFICOLK_01218 5.4e-13
EAFICOLK_01219 2.2e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAFICOLK_01220 2.1e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EAFICOLK_01221 2.9e-207 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EAFICOLK_01222 1.2e-178 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EAFICOLK_01223 2.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
EAFICOLK_01224 1.6e-180 pbuG S permease
EAFICOLK_01226 1e-78 S Cell surface protein
EAFICOLK_01228 1.2e-255 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
EAFICOLK_01229 2.2e-61
EAFICOLK_01230 3.6e-41 rpmE2 J Ribosomal protein L31
EAFICOLK_01231 4.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EAFICOLK_01232 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EAFICOLK_01235 1.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EAFICOLK_01236 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EAFICOLK_01237 1.8e-32 ywiB S Domain of unknown function (DUF1934)
EAFICOLK_01238 2.6e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
EAFICOLK_01239 4.3e-205 ywfO S HD domain protein
EAFICOLK_01240 5.2e-89 S hydrolase
EAFICOLK_01241 1.2e-102 ydcZ S Putative inner membrane exporter, YdcZ
EAFICOLK_01242 2.8e-22
EAFICOLK_01243 1.5e-72
EAFICOLK_01245 3.2e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
EAFICOLK_01246 3.9e-22
EAFICOLK_01247 3.9e-56 spoVK O ATPase family associated with various cellular activities (AAA)
EAFICOLK_01249 1.7e-86 S overlaps another CDS with the same product name
EAFICOLK_01250 4.8e-122 S overlaps another CDS with the same product name
EAFICOLK_01251 9.8e-177 L Probable transposase
EAFICOLK_01252 3.6e-100 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EAFICOLK_01253 1.1e-62 bCE_4747 S Beta-lactamase superfamily domain
EAFICOLK_01254 1.4e-290 ybiT S ABC transporter, ATP-binding protein
EAFICOLK_01255 3.9e-78 2.4.2.3 F Phosphorylase superfamily
EAFICOLK_01256 1.7e-24
EAFICOLK_01257 5.8e-112 dkg S reductase
EAFICOLK_01258 1.3e-18 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EAFICOLK_01259 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAFICOLK_01260 5.1e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EAFICOLK_01261 4.3e-47 EGP Transmembrane secretion effector
EAFICOLK_01262 5.2e-137 purR 2.4.2.7 F pur operon repressor
EAFICOLK_01263 2.1e-28 adhR K helix_turn_helix, mercury resistance
EAFICOLK_01264 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAFICOLK_01265 1.2e-103 pfoS S Phosphotransferase system, EIIC
EAFICOLK_01266 4.4e-127 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAFICOLK_01267 3.1e-151 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
EAFICOLK_01268 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EAFICOLK_01269 3.8e-201 argH 4.3.2.1 E argininosuccinate lyase
EAFICOLK_01271 1.3e-155 amtB P ammonium transporter
EAFICOLK_01272 3.7e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EAFICOLK_01273 6.6e-46 argR K Regulates arginine biosynthesis genes
EAFICOLK_01274 3.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
EAFICOLK_01275 2.8e-90 S Alpha/beta hydrolase of unknown function (DUF915)
EAFICOLK_01276 1.2e-22 veg S Biofilm formation stimulator VEG
EAFICOLK_01277 2.9e-133 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EAFICOLK_01278 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EAFICOLK_01279 3.5e-103 tatD L hydrolase, TatD family
EAFICOLK_01280 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAFICOLK_01281 3.9e-128
EAFICOLK_01282 1e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EAFICOLK_01283 1.5e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
EAFICOLK_01284 1.3e-31 K Bacterial regulatory proteins, tetR family
EAFICOLK_01285 5.4e-105 ybhR V ABC transporter
EAFICOLK_01286 9.3e-82 ybhF_2 V abc transporter atp-binding protein
EAFICOLK_01287 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EAFICOLK_01288 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
EAFICOLK_01289 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EAFICOLK_01290 1.5e-271 helD 3.6.4.12 L DNA helicase
EAFICOLK_01292 1.3e-114 htpX O Belongs to the peptidase M48B family
EAFICOLK_01293 2.2e-70 lemA S LemA family
EAFICOLK_01294 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
EAFICOLK_01295 1.1e-50 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
EAFICOLK_01296 2.9e-138 L Belongs to the 'phage' integrase family
EAFICOLK_01297 5.1e-242 hsdM 2.1.1.72 V HsdM N-terminal domain
EAFICOLK_01298 5.7e-92 3.1.21.3 V Type I restriction modification DNA specificity domain
EAFICOLK_01299 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EAFICOLK_01300 9.9e-47 3.1.21.3 V Type I restriction modification DNA specificity domain
EAFICOLK_01301 2.2e-264 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
EAFICOLK_01302 1.2e-170 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
EAFICOLK_01303 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
EAFICOLK_01304 5.1e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
EAFICOLK_01305 2.6e-83 drgA C nitroreductase
EAFICOLK_01306 7.4e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
EAFICOLK_01307 1.3e-69 metI P ABC transporter permease
EAFICOLK_01308 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAFICOLK_01309 2.3e-83 metQ1 P Belongs to the nlpA lipoprotein family
EAFICOLK_01310 2.9e-143 2.1.1.14 E methionine synthase, vitamin-B12 independent
EAFICOLK_01313 7.2e-18
EAFICOLK_01314 5.8e-100 V domain protein
EAFICOLK_01315 2.2e-119 xth 3.1.11.2 L exodeoxyribonuclease III
EAFICOLK_01316 2e-17
EAFICOLK_01317 1.1e-104 azlC E AzlC protein
EAFICOLK_01318 1.3e-38 azlD S branched-chain amino acid
EAFICOLK_01319 2.1e-66 I alpha/beta hydrolase fold
EAFICOLK_01320 3.1e-25
EAFICOLK_01321 1.2e-58 3.6.1.27 I phosphatase
EAFICOLK_01322 1.2e-22
EAFICOLK_01323 2.4e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EAFICOLK_01324 3.1e-89 sirR K Helix-turn-helix diphteria tox regulatory element
EAFICOLK_01325 4e-27 cspC K Cold shock protein
EAFICOLK_01326 4.3e-82 thrE S Putative threonine/serine exporter
EAFICOLK_01327 1.5e-34 S Threonine/Serine exporter, ThrE
EAFICOLK_01328 3.7e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EAFICOLK_01329 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
EAFICOLK_01330 5.5e-34 trxA O Belongs to the thioredoxin family
EAFICOLK_01331 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EAFICOLK_01332 1.1e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EAFICOLK_01333 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
EAFICOLK_01335 1.3e-53 queT S QueT transporter
EAFICOLK_01336 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
EAFICOLK_01337 2.5e-101 IQ Enoyl-(Acyl carrier protein) reductase
EAFICOLK_01338 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EAFICOLK_01339 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EAFICOLK_01340 5e-87 S Alpha beta hydrolase
EAFICOLK_01341 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EAFICOLK_01342 3.6e-140 V MatE
EAFICOLK_01343 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
EAFICOLK_01344 2.6e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAFICOLK_01345 7.4e-97 V ABC transporter
EAFICOLK_01346 7.4e-132 bacI V MacB-like periplasmic core domain
EAFICOLK_01347 9e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EAFICOLK_01348 1.7e-26
EAFICOLK_01349 2.1e-180 yhdP S Transporter associated domain
EAFICOLK_01350 5.4e-80 ptp2 3.1.3.48 T Tyrosine phosphatase family
EAFICOLK_01351 0.0 L Helicase C-terminal domain protein
EAFICOLK_01352 3.3e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EAFICOLK_01353 1.3e-212 yfnA E Amino Acid
EAFICOLK_01354 3.2e-53 zur P Belongs to the Fur family
EAFICOLK_01356 2.5e-97
EAFICOLK_01357 5.1e-08
EAFICOLK_01358 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EAFICOLK_01359 8.7e-100 glnH ET ABC transporter
EAFICOLK_01360 1.2e-85 gluC P ABC transporter permease
EAFICOLK_01361 9.6e-78 glnP P ABC transporter permease
EAFICOLK_01362 2.2e-190 steT E amino acid
EAFICOLK_01363 6.5e-21 K Acetyltransferase (GNAT) domain
EAFICOLK_01364 2.1e-145 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
EAFICOLK_01365 6.9e-55 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
EAFICOLK_01366 6.5e-79 K rpiR family
EAFICOLK_01367 1.4e-165 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EAFICOLK_01368 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EAFICOLK_01369 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EAFICOLK_01370 1e-100 rplD J Forms part of the polypeptide exit tunnel
EAFICOLK_01371 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EAFICOLK_01372 3.2e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EAFICOLK_01373 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EAFICOLK_01374 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EAFICOLK_01375 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EAFICOLK_01376 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EAFICOLK_01377 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
EAFICOLK_01378 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EAFICOLK_01379 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EAFICOLK_01380 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EAFICOLK_01381 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EAFICOLK_01382 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EAFICOLK_01383 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EAFICOLK_01384 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EAFICOLK_01385 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EAFICOLK_01386 3.8e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EAFICOLK_01387 2.1e-22 rpmD J Ribosomal protein L30
EAFICOLK_01388 1e-67 rplO J Binds to the 23S rRNA
EAFICOLK_01389 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EAFICOLK_01390 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EAFICOLK_01391 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EAFICOLK_01392 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EAFICOLK_01393 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EAFICOLK_01394 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EAFICOLK_01395 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EAFICOLK_01396 4.8e-53 rplQ J Ribosomal protein L17
EAFICOLK_01397 2.3e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EAFICOLK_01398 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EAFICOLK_01399 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EAFICOLK_01400 1.2e-124 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EAFICOLK_01401 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EAFICOLK_01402 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
EAFICOLK_01403 4e-30
EAFICOLK_01404 4.4e-245 yjbQ P TrkA C-terminal domain protein
EAFICOLK_01405 0.0 helD 3.6.4.12 L DNA helicase
EAFICOLK_01406 3.6e-68 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EAFICOLK_01407 2e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
EAFICOLK_01408 6.3e-111 hrtB V ABC transporter permease
EAFICOLK_01409 3.9e-34 ygfC K Bacterial regulatory proteins, tetR family
EAFICOLK_01410 1.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EAFICOLK_01411 1.1e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EAFICOLK_01412 2.1e-36 M LysM domain protein
EAFICOLK_01413 1.1e-113 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EAFICOLK_01414 1.3e-95 sbcC L Putative exonuclease SbcCD, C subunit
EAFICOLK_01415 9.9e-58 S LexA-binding, inner membrane-associated putative hydrolase
EAFICOLK_01416 7.2e-53 perR P Belongs to the Fur family
EAFICOLK_01417 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EAFICOLK_01418 8.1e-142 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAFICOLK_01419 5.5e-86 S (CBS) domain
EAFICOLK_01420 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EAFICOLK_01421 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EAFICOLK_01422 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EAFICOLK_01423 5.6e-140 yabM S Polysaccharide biosynthesis protein
EAFICOLK_01424 3.6e-31 yabO J S4 domain protein
EAFICOLK_01425 1e-21 divIC D Septum formation initiator
EAFICOLK_01426 1.1e-40 yabR J RNA binding
EAFICOLK_01427 1.6e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EAFICOLK_01428 1.9e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EAFICOLK_01429 4.6e-283 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAFICOLK_01430 3.2e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EAFICOLK_01431 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAFICOLK_01432 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EAFICOLK_01433 1.7e-93 yihY S Belongs to the UPF0761 family
EAFICOLK_01434 6.2e-12 mltD CBM50 M Lysin motif
EAFICOLK_01435 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EAFICOLK_01436 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
EAFICOLK_01437 5.1e-54 fld C Flavodoxin
EAFICOLK_01438 8.7e-53 gtcA S Teichoic acid glycosylation protein
EAFICOLK_01439 0.0 S Bacterial membrane protein YfhO
EAFICOLK_01440 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
EAFICOLK_01441 1.7e-122 S Sulfite exporter TauE/SafE
EAFICOLK_01442 1.1e-70 K Sugar-specific transcriptional regulator TrmB
EAFICOLK_01443 2.1e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EAFICOLK_01444 3.5e-182 pepS E Thermophilic metalloprotease (M29)
EAFICOLK_01445 4.3e-265 E Amino acid permease
EAFICOLK_01446 4.9e-85 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
EAFICOLK_01447 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
EAFICOLK_01448 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
EAFICOLK_01449 4.3e-213 malT G Transporter, major facilitator family protein
EAFICOLK_01450 4.2e-101 malR K Transcriptional regulator, LacI family
EAFICOLK_01451 2.3e-279 kup P Transport of potassium into the cell
EAFICOLK_01453 2e-20 S Domain of unknown function (DUF3284)
EAFICOLK_01454 5.2e-160 yfmL L DEAD DEAH box helicase
EAFICOLK_01455 5.4e-128 mocA S Oxidoreductase
EAFICOLK_01456 2e-24 S Domain of unknown function (DUF4828)
EAFICOLK_01457 1.9e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
EAFICOLK_01458 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EAFICOLK_01459 2.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
EAFICOLK_01460 1.4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
EAFICOLK_01461 1.9e-30 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EAFICOLK_01462 2.9e-42 O ADP-ribosylglycohydrolase
EAFICOLK_01463 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
EAFICOLK_01464 2.2e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
EAFICOLK_01465 1.3e-34 K GNAT family
EAFICOLK_01466 1.7e-40
EAFICOLK_01468 5.5e-160 mgtE P Acts as a magnesium transporter
EAFICOLK_01469 9.7e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
EAFICOLK_01470 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EAFICOLK_01471 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
EAFICOLK_01472 2.5e-257 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
EAFICOLK_01473 3.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
EAFICOLK_01474 1.7e-193 pbuX F xanthine permease
EAFICOLK_01475 3.3e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EAFICOLK_01476 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
EAFICOLK_01477 3.2e-64 S ECF transporter, substrate-specific component
EAFICOLK_01478 4.3e-127 mleP S Sodium Bile acid symporter family
EAFICOLK_01479 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
EAFICOLK_01480 6.2e-72 mleR K LysR family
EAFICOLK_01481 1.1e-56 K transcriptional
EAFICOLK_01482 2.6e-41 K Bacterial regulatory proteins, tetR family
EAFICOLK_01483 6.1e-60 T Belongs to the universal stress protein A family
EAFICOLK_01484 1.2e-44 K Copper transport repressor CopY TcrY
EAFICOLK_01485 5.3e-71 3.2.1.18 GH33 M Rib/alpha-like repeat
EAFICOLK_01486 1.7e-96 ypuA S Protein of unknown function (DUF1002)
EAFICOLK_01487 6.9e-62 dedA 3.1.3.1 S SNARE associated Golgi protein
EAFICOLK_01488 6.7e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAFICOLK_01489 2.6e-18 yncA 2.3.1.79 S Maltose acetyltransferase
EAFICOLK_01490 1.5e-205 yflS P Sodium:sulfate symporter transmembrane region
EAFICOLK_01491 4.7e-199 frdC 1.3.5.4 C FAD binding domain
EAFICOLK_01492 2.1e-236 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EAFICOLK_01493 2e-14 ybaN S Protein of unknown function (DUF454)
EAFICOLK_01494 2.2e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
EAFICOLK_01495 2.6e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EAFICOLK_01496 7.3e-97 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAFICOLK_01497 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EAFICOLK_01498 1.1e-71 ywlG S Belongs to the UPF0340 family
EAFICOLK_01499 1.5e-158 C Oxidoreductase
EAFICOLK_01500 5e-176 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
EAFICOLK_01501 2.9e-73 S Domain of unknown function (DUF3841)
EAFICOLK_01502 2.9e-08 cdd 2.4.2.4, 3.5.4.5 J Acetyltransferase (GNAT) domain
EAFICOLK_01503 5.2e-34 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
EAFICOLK_01504 2.2e-102 S Domain of unknown function (DUF4343)
EAFICOLK_01505 0.0 L helicase activity
EAFICOLK_01506 7.2e-186 K DNA binding
EAFICOLK_01507 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
EAFICOLK_01508 8.9e-202 mod 2.1.1.72, 3.1.21.5 L DNA methylase
EAFICOLK_01509 1.4e-163 mcrC V Psort location Cytoplasmic, score
EAFICOLK_01510 0.0 mcrB 2.1.1.72 V ATPase family associated with various cellular activities (AAA)
EAFICOLK_01511 2.7e-10
EAFICOLK_01512 5.4e-13
EAFICOLK_01513 3.2e-112 S Protein of unknown function (DUF1349)
EAFICOLK_01514 4e-211 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAFICOLK_01515 9.8e-146 yegS 2.7.1.107 G Lipid kinase
EAFICOLK_01516 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAFICOLK_01517 1.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EAFICOLK_01518 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAFICOLK_01519 7.1e-161 camS S sex pheromone
EAFICOLK_01520 1.1e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EAFICOLK_01521 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EAFICOLK_01522 5.4e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EAFICOLK_01526 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
EAFICOLK_01527 5.2e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
EAFICOLK_01529 6.2e-64 srtA 3.4.22.70 M sortase family
EAFICOLK_01530 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EAFICOLK_01531 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EAFICOLK_01532 1.4e-33
EAFICOLK_01533 3.1e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAFICOLK_01534 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EAFICOLK_01535 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EAFICOLK_01536 5.3e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
EAFICOLK_01537 2.5e-39 ybjQ S Belongs to the UPF0145 family
EAFICOLK_01538 1e-09
EAFICOLK_01539 1.5e-94 V ABC transporter, ATP-binding protein
EAFICOLK_01540 1.1e-41 gntR1 K Transcriptional regulator, GntR family
EAFICOLK_01541 5.4e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
EAFICOLK_01542 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EAFICOLK_01543 1.2e-260 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
EAFICOLK_01544 2.2e-107 terC P Integral membrane protein TerC family
EAFICOLK_01545 1.6e-38 K Transcriptional regulator
EAFICOLK_01546 9.8e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EAFICOLK_01547 1.2e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EAFICOLK_01548 4.5e-102 tcyB E ABC transporter
EAFICOLK_01550 4.8e-59 ganB 3.2.1.89 G arabinogalactan
EAFICOLK_01551 3.6e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
EAFICOLK_01552 1.3e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EAFICOLK_01553 3.4e-209 mtlR K Mga helix-turn-helix domain
EAFICOLK_01554 2.2e-176 yjcE P Sodium proton antiporter
EAFICOLK_01555 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EAFICOLK_01556 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
EAFICOLK_01557 5.6e-69 dhaL 2.7.1.121 S Dak2
EAFICOLK_01558 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
EAFICOLK_01559 4.2e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
EAFICOLK_01560 1.7e-61 K Bacterial regulatory proteins, tetR family
EAFICOLK_01561 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
EAFICOLK_01563 1.7e-111 endA F DNA RNA non-specific endonuclease
EAFICOLK_01564 1.6e-74 XK27_02070 S Nitroreductase family
EAFICOLK_01565 2e-192 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
EAFICOLK_01566 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
EAFICOLK_01567 8e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
EAFICOLK_01568 9.4e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
EAFICOLK_01569 1.6e-58 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
EAFICOLK_01570 5.1e-77 azlC E branched-chain amino acid
EAFICOLK_01571 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
EAFICOLK_01572 2.6e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
EAFICOLK_01573 2.1e-55 jag S R3H domain protein
EAFICOLK_01574 5.3e-54 K Transcriptional regulator C-terminal region
EAFICOLK_01575 5.9e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
EAFICOLK_01576 6.2e-287 pepO 3.4.24.71 O Peptidase family M13
EAFICOLK_01577 2.2e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
EAFICOLK_01578 9.5e-70 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
EAFICOLK_01579 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
EAFICOLK_01580 7.4e-41 wecD K Acetyltransferase GNAT Family
EAFICOLK_01582 5e-255 XK27_06780 V ABC transporter permease
EAFICOLK_01583 1.1e-95 XK27_06785 V ABC transporter, ATP-binding protein
EAFICOLK_01585 9.4e-101 ybbM S Uncharacterised protein family (UPF0014)
EAFICOLK_01586 2e-67 ybbL S ABC transporter
EAFICOLK_01587 1.4e-162 oxlT P Major Facilitator Superfamily
EAFICOLK_01588 4.7e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EAFICOLK_01589 4.1e-47 S Short repeat of unknown function (DUF308)
EAFICOLK_01590 3e-30 tetR K Transcriptional regulator C-terminal region
EAFICOLK_01591 1.2e-150 yfeX P Peroxidase
EAFICOLK_01592 2.5e-16 S Protein of unknown function (DUF3021)
EAFICOLK_01593 5.8e-39 K LytTr DNA-binding domain
EAFICOLK_01594 1.8e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
EAFICOLK_01595 1.7e-209 mmuP E amino acid
EAFICOLK_01596 9.2e-16 psiE S Phosphate-starvation-inducible E
EAFICOLK_01597 2.8e-155 oppF P Belongs to the ABC transporter superfamily
EAFICOLK_01598 1.3e-180 oppD P Belongs to the ABC transporter superfamily
EAFICOLK_01599 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAFICOLK_01600 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAFICOLK_01601 3.6e-203 oppA E ABC transporter, substratebinding protein
EAFICOLK_01602 5.9e-218 yifK E Amino acid permease
EAFICOLK_01603 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EAFICOLK_01604 1.1e-56 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
EAFICOLK_01605 5e-66 pgm3 G phosphoglycerate mutase family
EAFICOLK_01606 5.5e-251 ctpA 3.6.3.54 P P-type ATPase
EAFICOLK_01607 1.3e-20 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EAFICOLK_01608 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EAFICOLK_01609 6.7e-151 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EAFICOLK_01610 1.8e-181 EG GntP family permease
EAFICOLK_01611 5e-116 KT Putative sugar diacid recognition
EAFICOLK_01612 3.1e-22 K transcriptional regulator
EAFICOLK_01613 6.1e-75 hchA S intracellular protease amidase
EAFICOLK_01614 3.9e-137 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
EAFICOLK_01615 8.7e-81 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EAFICOLK_01616 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EAFICOLK_01617 1.3e-149 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
EAFICOLK_01618 1.1e-27 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
EAFICOLK_01619 5.8e-118 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
EAFICOLK_01620 2.6e-197 1.3.5.4 C FMN_bind
EAFICOLK_01621 1.7e-56 3.1.3.48 K Transcriptional regulator
EAFICOLK_01622 4.9e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
EAFICOLK_01623 3.1e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
EAFICOLK_01624 8.9e-76 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EAFICOLK_01625 1.6e-128 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)