ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMEEINBN_00001 8.1e-88 tag 3.2.2.20 L glycosylase
HMEEINBN_00002 4.9e-41 S Sugar efflux transporter for intercellular exchange
HMEEINBN_00003 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMEEINBN_00004 3.2e-227 rodA D Belongs to the SEDS family
HMEEINBN_00005 3.2e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMEEINBN_00006 6.9e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HMEEINBN_00007 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMEEINBN_00008 5.7e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMEEINBN_00009 4.6e-126 Q Methyltransferase domain
HMEEINBN_00010 1.5e-65 GnaT 2.5.1.16 K acetyltransferase
HMEEINBN_00011 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HMEEINBN_00012 9.9e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMEEINBN_00013 1e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HMEEINBN_00014 1.3e-125 dnaD
HMEEINBN_00015 4.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMEEINBN_00017 1.5e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMEEINBN_00018 1.8e-28 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMEEINBN_00019 1.9e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMEEINBN_00020 1.9e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HMEEINBN_00021 8.3e-73 argR K Regulates arginine biosynthesis genes
HMEEINBN_00022 1.8e-301 recN L May be involved in recombinational repair of damaged DNA
HMEEINBN_00023 4.4e-144 DegV S DegV family
HMEEINBN_00024 2.3e-159 ypmR E COG2755 Lysophospholipase L1 and related esterases
HMEEINBN_00025 1.8e-96 ypmS S Protein conserved in bacteria
HMEEINBN_00026 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMEEINBN_00028 3.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HMEEINBN_00029 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMEEINBN_00030 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMEEINBN_00031 3.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HMEEINBN_00032 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMEEINBN_00033 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMEEINBN_00034 0.0 dnaE 2.7.7.7 L DNA polymerase
HMEEINBN_00035 1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMEEINBN_00036 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMEEINBN_00037 2.5e-25 Q the current gene model (or a revised gene model) may contain a frame shift
HMEEINBN_00038 2.3e-221 pbuX F xanthine permease
HMEEINBN_00039 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMEEINBN_00040 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMEEINBN_00041 9.7e-151 T Histidine kinase
HMEEINBN_00042 1.1e-133 macB2 V ABC transporter, ATP-binding protein
HMEEINBN_00043 0.0 V ABC transporter (permease)
HMEEINBN_00044 6.1e-93 XK27_05000 S metal cluster binding
HMEEINBN_00045 1.3e-29 liaI KT membrane
HMEEINBN_00046 1.8e-15 liaI KT membrane
HMEEINBN_00047 9e-156 XK27_09825 V abc transporter atp-binding protein
HMEEINBN_00048 2.2e-115 yvfS V Transporter
HMEEINBN_00049 7.5e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
HMEEINBN_00050 3.3e-164 yocS S Transporter
HMEEINBN_00051 0.0 hscC O Belongs to the heat shock protein 70 family
HMEEINBN_00052 4.8e-233 anK3 G response to abiotic stimulus
HMEEINBN_00054 6.7e-208 2.4.1.276 GT1 CG transferase activity, transferring hexosyl groups
HMEEINBN_00055 2.4e-100
HMEEINBN_00056 1.6e-197 ugcG 2.4.1.80 GT21 M transferase activity, transferring glycosyl groups
HMEEINBN_00057 3.1e-107 1.1.1.105 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMEEINBN_00058 5e-232 2.4.1.276 GT1 CG Glycosyltransferase family 28 C-terminal domain
HMEEINBN_00059 1.3e-179 ybjS 1.1.1.133, 5.1.3.13 M NAD dependent epimerase dehydratase family protein
HMEEINBN_00060 3e-153 gumP S Metallo-beta-lactamase superfamily
HMEEINBN_00061 3.6e-238 6.2.1.30 H Coenzyme F390 synthetase
HMEEINBN_00062 2.1e-171 fabH 2.3.1.180 I synthase III
HMEEINBN_00065 1.3e-159 XK27_09825 V 'abc transporter, ATP-binding protein
HMEEINBN_00066 6.9e-133 yvfS V ABC-2 type transporter
HMEEINBN_00067 1.9e-187 desK 2.7.13.3 T Histidine kinase
HMEEINBN_00068 9.7e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMEEINBN_00069 8.8e-207 S Protein of unknown function DUF262
HMEEINBN_00070 8.8e-125 S Protein of unknown function DUF262
HMEEINBN_00071 4.3e-85 yfjR K regulation of single-species biofilm formation
HMEEINBN_00074 6.8e-184 S AAA domain, putative AbiEii toxin, Type IV TA system
HMEEINBN_00075 4e-142 S ABC-2 family transporter protein
HMEEINBN_00076 1.1e-141 S ABC-2 family transporter protein
HMEEINBN_00077 8.3e-76 K Acetyltransferase (GNAT) domain
HMEEINBN_00078 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
HMEEINBN_00079 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HMEEINBN_00080 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMEEINBN_00081 8.8e-229 cinA 3.5.1.42 S Belongs to the CinA family
HMEEINBN_00082 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HMEEINBN_00083 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMEEINBN_00085 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMEEINBN_00087 1.1e-69 K LytTr DNA-binding domain
HMEEINBN_00088 1.5e-77 S Protein of unknown function (DUF3021)
HMEEINBN_00089 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMEEINBN_00090 5.3e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HMEEINBN_00091 3.4e-68 argR K Regulates arginine biosynthesis genes
HMEEINBN_00092 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HMEEINBN_00093 4.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMEEINBN_00094 8.5e-110 S AIPR protein
HMEEINBN_00098 1.4e-15
HMEEINBN_00099 4.3e-200 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMEEINBN_00100 5.3e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMEEINBN_00101 4.3e-236 purD 6.3.4.13 F Belongs to the GARS family
HMEEINBN_00102 1.2e-157 S CHAP domain
HMEEINBN_00103 2.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HMEEINBN_00104 4.9e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMEEINBN_00105 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HMEEINBN_00106 7.8e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMEEINBN_00107 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMEEINBN_00108 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HMEEINBN_00109 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMEEINBN_00110 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMEEINBN_00111 8e-140 recO L Involved in DNA repair and RecF pathway recombination
HMEEINBN_00112 1.1e-217 araT 2.6.1.1 E Aminotransferase
HMEEINBN_00113 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMEEINBN_00114 2.1e-83 usp 3.5.1.28 CBM50 S CHAP domain
HMEEINBN_00115 7.9e-83 mreD M rod shape-determining protein MreD
HMEEINBN_00116 1.2e-109 mreC M Involved in formation and maintenance of cell shape
HMEEINBN_00123 1.9e-86 sigH K DNA-templated transcription, initiation
HMEEINBN_00124 5.8e-138 ykuT M mechanosensitive ion channel
HMEEINBN_00125 5.8e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMEEINBN_00126 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMEEINBN_00127 3.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMEEINBN_00128 3.8e-84 XK27_03960 S Protein of unknown function (DUF3013)
HMEEINBN_00129 2.4e-75 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HMEEINBN_00130 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
HMEEINBN_00131 9.1e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMEEINBN_00132 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMEEINBN_00133 5.9e-82 nrdI F Belongs to the NrdI family
HMEEINBN_00134 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMEEINBN_00135 3.7e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMEEINBN_00136 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HMEEINBN_00137 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HMEEINBN_00138 2.1e-111 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMEEINBN_00139 3.4e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HMEEINBN_00140 3.8e-194 yhjX P Major Facilitator
HMEEINBN_00141 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMEEINBN_00142 9.5e-85 V VanZ like family
HMEEINBN_00143 6e-184 D nuclear chromosome segregation
HMEEINBN_00144 2.2e-123 glnQ E abc transporter atp-binding protein
HMEEINBN_00145 2.7e-272 glnP P ABC transporter
HMEEINBN_00146 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMEEINBN_00147 3.7e-18 S Protein of unknown function (DUF3021)
HMEEINBN_00148 9.8e-127 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMEEINBN_00149 5.1e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
HMEEINBN_00150 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HMEEINBN_00151 1.2e-233 sufD O assembly protein SufD
HMEEINBN_00152 8.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMEEINBN_00153 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
HMEEINBN_00154 2.9e-273 sufB O assembly protein SufB
HMEEINBN_00155 4.7e-26
HMEEINBN_00156 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMEEINBN_00157 1.1e-181 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMEEINBN_00158 1e-70 adcR K transcriptional
HMEEINBN_00159 5.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
HMEEINBN_00160 5.6e-128 adcB P ABC transporter (Permease
HMEEINBN_00161 5.3e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HMEEINBN_00162 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMEEINBN_00163 8.9e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
HMEEINBN_00164 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
HMEEINBN_00165 3.7e-87 L COG1943 Transposase and inactivated derivatives
HMEEINBN_00166 2.3e-151 Z012_04635 K sequence-specific DNA binding
HMEEINBN_00167 1.2e-280 V ABC transporter
HMEEINBN_00168 6.1e-126 yeeN K transcriptional regulatory protein
HMEEINBN_00169 5.9e-47 yajC U protein transport
HMEEINBN_00170 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMEEINBN_00171 9.3e-144 cdsA 2.7.7.41 S Belongs to the CDS family
HMEEINBN_00172 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMEEINBN_00173 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMEEINBN_00174 0.0 WQ51_06230 S ABC transporter
HMEEINBN_00175 6.8e-142 cmpC S abc transporter atp-binding protein
HMEEINBN_00176 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMEEINBN_00177 8.2e-288 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMEEINBN_00179 5.5e-44
HMEEINBN_00180 1.7e-54 S TM2 domain
HMEEINBN_00181 2.6e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMEEINBN_00182 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMEEINBN_00183 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMEEINBN_00184 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
HMEEINBN_00185 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HMEEINBN_00186 4.9e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HMEEINBN_00187 5.6e-144 cof S Sucrose-6F-phosphate phosphohydrolase
HMEEINBN_00188 7.9e-132 glcR K transcriptional regulator (DeoR family)
HMEEINBN_00189 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMEEINBN_00190 7.6e-74 K helix_turn_helix multiple antibiotic resistance protein
HMEEINBN_00191 7.3e-234 S COG1073 Hydrolases of the alpha beta superfamily
HMEEINBN_00192 2.5e-150 cylA V abc transporter atp-binding protein
HMEEINBN_00193 1.5e-128 cylB V ABC-2 type transporter
HMEEINBN_00194 9e-75 K COG3279 Response regulator of the LytR AlgR family
HMEEINBN_00195 2e-31 S Protein of unknown function (DUF3021)
HMEEINBN_00196 7.4e-124 mta K Transcriptional
HMEEINBN_00197 4.7e-120 yhcA V abc transporter atp-binding protein
HMEEINBN_00198 3.9e-216 macB_2 V FtsX-like permease family
HMEEINBN_00199 7.4e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMEEINBN_00200 5.8e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMEEINBN_00201 1.4e-72 yhaI S Protein of unknown function (DUF805)
HMEEINBN_00202 1.3e-254 pepC 3.4.22.40 E aminopeptidase
HMEEINBN_00203 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMEEINBN_00204 1.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMEEINBN_00205 5.8e-94 ypsA S Belongs to the UPF0398 family
HMEEINBN_00206 2.1e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMEEINBN_00207 1.9e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMEEINBN_00208 2.4e-281 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HMEEINBN_00209 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HMEEINBN_00210 9.6e-23
HMEEINBN_00211 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMEEINBN_00212 1.5e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
HMEEINBN_00213 7.1e-302 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMEEINBN_00214 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMEEINBN_00215 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMEEINBN_00216 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMEEINBN_00217 7.9e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMEEINBN_00218 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HMEEINBN_00219 2.2e-101 ybhL S Belongs to the BI1 family
HMEEINBN_00220 5.5e-12 ycdA S Domain of unknown function (DUF4352)
HMEEINBN_00221 3.1e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMEEINBN_00222 1.8e-90 K transcriptional regulator
HMEEINBN_00223 1.6e-36 yneF S UPF0154 protein
HMEEINBN_00224 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMEEINBN_00225 6.6e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMEEINBN_00226 3.9e-98 XK27_09740 S Phosphoesterase
HMEEINBN_00227 8.3e-87 ykuL S CBS domain
HMEEINBN_00228 2.5e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HMEEINBN_00229 1.8e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMEEINBN_00230 1.3e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMEEINBN_00231 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMEEINBN_00232 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
HMEEINBN_00233 1.1e-259 trkH P Cation transport protein
HMEEINBN_00234 1.7e-246 trkA P Potassium transporter peripheral membrane component
HMEEINBN_00235 5.1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMEEINBN_00236 6e-89 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMEEINBN_00237 2.7e-109 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HMEEINBN_00238 7.3e-153 K sequence-specific DNA binding
HMEEINBN_00239 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMEEINBN_00240 1.3e-54 yhaI L Membrane
HMEEINBN_00241 5.5e-248 S Domain of unknown function (DUF4173)
HMEEINBN_00242 6.8e-95 ureI S AmiS/UreI family transporter
HMEEINBN_00243 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HMEEINBN_00244 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HMEEINBN_00245 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HMEEINBN_00246 6.6e-78 ureE O enzyme active site formation
HMEEINBN_00247 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HMEEINBN_00248 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HMEEINBN_00249 1.1e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HMEEINBN_00250 3.9e-176 cbiM P biosynthesis protein CbiM
HMEEINBN_00251 1.1e-136 P cobalt transport protein
HMEEINBN_00252 6.3e-131 cbiO P ABC transporter
HMEEINBN_00253 1.3e-143 ET amino acid transport
HMEEINBN_00254 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
HMEEINBN_00255 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HMEEINBN_00256 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMEEINBN_00257 1.2e-99 metI P ABC transporter (Permease
HMEEINBN_00258 3.3e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HMEEINBN_00259 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HMEEINBN_00260 6.7e-93 S UPF0397 protein
HMEEINBN_00261 6.7e-309 ykoD P abc transporter atp-binding protein
HMEEINBN_00262 4.5e-149 cbiQ P cobalt transport
HMEEINBN_00263 8e-120 ktrA P COG0569 K transport systems, NAD-binding component
HMEEINBN_00264 2.1e-236 P COG0168 Trk-type K transport systems, membrane components
HMEEINBN_00265 4.9e-128 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HMEEINBN_00266 6.2e-91 yceD K metal-binding, possibly nucleic acid-binding protein
HMEEINBN_00267 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMEEINBN_00268 5.9e-280 T PhoQ Sensor
HMEEINBN_00269 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMEEINBN_00270 3.3e-214 dnaB L Replication initiation and membrane attachment
HMEEINBN_00271 1.3e-165 dnaI L Primosomal protein DnaI
HMEEINBN_00272 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMEEINBN_00273 4e-113
HMEEINBN_00274 1.4e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMEEINBN_00275 2.5e-62 manO S protein conserved in bacteria
HMEEINBN_00276 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
HMEEINBN_00277 4.5e-117 manM G pts system
HMEEINBN_00278 4.9e-174 manL 2.7.1.191 G pts system
HMEEINBN_00279 7.7e-67 manO S Protein conserved in bacteria
HMEEINBN_00280 9.4e-164 manN G PTS system mannose fructose sorbose family IID component
HMEEINBN_00281 4.7e-135 manY G pts system
HMEEINBN_00282 6.2e-169 manL 2.7.1.191 G pts system
HMEEINBN_00283 7.3e-135 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HMEEINBN_00284 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HMEEINBN_00285 1.6e-247 pbuO S permease
HMEEINBN_00286 1.2e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HMEEINBN_00287 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
HMEEINBN_00288 9.8e-188 brpA K Transcriptional
HMEEINBN_00289 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
HMEEINBN_00290 7.1e-196 nusA K Participates in both transcription termination and antitermination
HMEEINBN_00291 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HMEEINBN_00292 1.4e-41 ylxQ J ribosomal protein
HMEEINBN_00293 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMEEINBN_00294 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMEEINBN_00295 1e-99 yvdD 3.2.2.10 S Belongs to the LOG family
HMEEINBN_00296 1.1e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HMEEINBN_00297 9.9e-269 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMEEINBN_00298 5.4e-287 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HMEEINBN_00299 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HMEEINBN_00300 4.4e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
HMEEINBN_00301 1.1e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HMEEINBN_00302 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HMEEINBN_00303 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
HMEEINBN_00304 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMEEINBN_00305 1.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMEEINBN_00306 1.4e-72 ylbF S Belongs to the UPF0342 family
HMEEINBN_00307 1.9e-46 ylbG S UPF0298 protein
HMEEINBN_00308 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HMEEINBN_00309 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
HMEEINBN_00310 6.3e-139 livM E Belongs to the binding-protein-dependent transport system permease family
HMEEINBN_00311 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HMEEINBN_00312 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HMEEINBN_00313 3.5e-112 acuB S CBS domain
HMEEINBN_00314 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMEEINBN_00315 4.5e-109 yvyE 3.4.13.9 S YigZ family
HMEEINBN_00316 3.6e-249 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HMEEINBN_00317 2.6e-83 comFC K competence protein
HMEEINBN_00318 4.7e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMEEINBN_00319 1.9e-59 tcyB_2 P ABC transporter (permease)
HMEEINBN_00320 3.2e-153 endA F DNA RNA non-specific endonuclease
HMEEINBN_00321 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
HMEEINBN_00322 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMEEINBN_00324 3.3e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMEEINBN_00325 3.2e-134 G Domain of unknown function (DUF4832)
HMEEINBN_00326 9.2e-84 S membrane
HMEEINBN_00327 6.7e-96 P VTC domain
HMEEINBN_00328 1.3e-222 cotH M CotH kinase protein
HMEEINBN_00329 1.1e-182 pelG M Putative exopolysaccharide Exporter (EPS-E)
HMEEINBN_00330 3e-270 pelF GT4 M Domain of unknown function (DUF3492)
HMEEINBN_00331 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
HMEEINBN_00332 4.8e-144
HMEEINBN_00333 6e-276 5.1.3.2 GM Psort location CytoplasmicMembrane, score
HMEEINBN_00334 1.2e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMEEINBN_00335 1.5e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMEEINBN_00336 8.3e-304 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMEEINBN_00337 2.3e-87 ytsP 1.8.4.14 T GAF domain-containing protein
HMEEINBN_00338 1.4e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMEEINBN_00339 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
HMEEINBN_00342 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMEEINBN_00343 3.3e-212 XK27_05110 P Chloride transporter ClC family
HMEEINBN_00344 4.7e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HMEEINBN_00345 1e-279 clcA P Chloride transporter, ClC family
HMEEINBN_00346 1e-75 fld C Flavodoxin
HMEEINBN_00347 2.8e-18 XK27_08880
HMEEINBN_00348 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
HMEEINBN_00349 8.6e-150 estA CE1 S Esterase
HMEEINBN_00350 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMEEINBN_00351 8.9e-136 XK27_08845 S abc transporter atp-binding protein
HMEEINBN_00352 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HMEEINBN_00353 2.4e-176 XK27_08835 S ABC transporter substrate binding protein
HMEEINBN_00354 1.7e-18 S Domain of unknown function (DUF4649)
HMEEINBN_00355 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
HMEEINBN_00356 7.9e-180 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HMEEINBN_00357 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMEEINBN_00358 5e-138 ycdO P periplasmic lipoprotein involved in iron transport
HMEEINBN_00359 6.2e-232 ycdB P peroxidase
HMEEINBN_00360 9.1e-290 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HMEEINBN_00361 1.1e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMEEINBN_00362 2.3e-24 tatA U protein secretion
HMEEINBN_00363 1.8e-212 msmX P Belongs to the ABC transporter superfamily
HMEEINBN_00364 3.7e-151 malG P ABC transporter (Permease
HMEEINBN_00365 1.1e-248 malF P ABC transporter (Permease
HMEEINBN_00366 1.5e-228 malX G ABC transporter
HMEEINBN_00367 3.5e-156 malR K Transcriptional regulator
HMEEINBN_00368 2.1e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
HMEEINBN_00369 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMEEINBN_00370 2e-38
HMEEINBN_00371 2.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
HMEEINBN_00372 1.9e-197
HMEEINBN_00373 3.5e-261 dnaG 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMEEINBN_00374 4.3e-22
HMEEINBN_00375 2e-217 EGP Transmembrane secretion effector
HMEEINBN_00376 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
HMEEINBN_00377 1.1e-49
HMEEINBN_00378 8.7e-60
HMEEINBN_00379 5.9e-55
HMEEINBN_00380 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMEEINBN_00381 2.3e-105 K Transcriptional regulator
HMEEINBN_00382 1.4e-130 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
HMEEINBN_00383 1.8e-255 6.1.1.6 S Psort location CytoplasmicMembrane, score
HMEEINBN_00384 5.4e-33 S Protein of unknown function (DUF1648)
HMEEINBN_00385 6e-55 K Transcriptional regulator
HMEEINBN_00386 4.2e-239
HMEEINBN_00387 0.0
HMEEINBN_00388 1.5e-65 L viral genome integration into host DNA
HMEEINBN_00389 1.2e-22 L Transposase (IS116 IS110 IS902 family)
HMEEINBN_00390 0.0 GM domain, Protein
HMEEINBN_00391 1.1e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMEEINBN_00392 0.0 sbcC L ATPase involved in DNA repair
HMEEINBN_00393 0.0 M family 8
HMEEINBN_00394 9.5e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HMEEINBN_00395 1.4e-289 asp1 S Accessory Sec system protein Asp1
HMEEINBN_00396 4.9e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
HMEEINBN_00397 1e-78 asp3 S Accessory Sec system protein Asp3
HMEEINBN_00398 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMEEINBN_00399 5.7e-283 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HMEEINBN_00400 1.2e-244 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HMEEINBN_00401 2.6e-17 S Accessory secretory protein Sec Asp4
HMEEINBN_00402 3.6e-16 S Accessory secretory protein Sec, Asp5
HMEEINBN_00403 7.3e-186 nss M transferase activity, transferring glycosyl groups
HMEEINBN_00405 6.1e-101 L recombinase activity
HMEEINBN_00408 1.4e-19
HMEEINBN_00411 0.0 S COG0433 Predicted ATPase
HMEEINBN_00412 2.5e-136 S Replication-relaxation
HMEEINBN_00414 5.5e-303 L Recombinase
HMEEINBN_00415 1.2e-114 pscB M CHAP domain protein
HMEEINBN_00416 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
HMEEINBN_00417 2.5e-62 glnR K Transcriptional regulator
HMEEINBN_00418 6.7e-87 S Fusaric acid resistance protein-like
HMEEINBN_00419 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMEEINBN_00420 1.9e-186 gap 1.2.1.12 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMEEINBN_00421 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMEEINBN_00422 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMEEINBN_00423 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMEEINBN_00424 4e-142 purR 2.4.2.7 F operon repressor
HMEEINBN_00425 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
HMEEINBN_00426 3.2e-170 rmuC S RmuC domain protein
HMEEINBN_00427 3.8e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMEEINBN_00428 3.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMEEINBN_00429 3.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMEEINBN_00431 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMEEINBN_00432 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMEEINBN_00433 3.6e-143 tatD L Hydrolase, tatd
HMEEINBN_00434 1.2e-73 yccU S CoA-binding protein
HMEEINBN_00435 2.4e-50 trxA O Belongs to the thioredoxin family
HMEEINBN_00436 1.7e-142 S Macro domain protein
HMEEINBN_00437 1.8e-61 L thioesterase
HMEEINBN_00438 7.2e-53 bta 1.8.1.8 CO cell redox homeostasis
HMEEINBN_00440 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMEEINBN_00441 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMEEINBN_00442 2.4e-234 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMEEINBN_00443 1.3e-235 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HMEEINBN_00445 3e-60 divIC D Septum formation initiator
HMEEINBN_00446 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HMEEINBN_00447 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMEEINBN_00448 8.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMEEINBN_00449 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMEEINBN_00450 1.1e-29 yyzM S Protein conserved in bacteria
HMEEINBN_00451 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMEEINBN_00452 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMEEINBN_00453 7.7e-135 parB K Belongs to the ParB family
HMEEINBN_00454 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HMEEINBN_00455 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMEEINBN_00456 4e-119 yoaK S Protein of unknown function (DUF1275)
HMEEINBN_00460 0.0 XK27_10405 S Bacterial membrane protein YfhO
HMEEINBN_00461 1.1e-305 ybiT S abc transporter atp-binding protein
HMEEINBN_00462 7.8e-152 yvjA S membrane
HMEEINBN_00463 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HMEEINBN_00464 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HMEEINBN_00465 5.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMEEINBN_00466 3.7e-58 yaaA S S4 domain protein YaaA
HMEEINBN_00467 1.1e-231 ymfF S Peptidase M16
HMEEINBN_00468 4.7e-238 ymfH S Peptidase M16
HMEEINBN_00469 2e-131 S sequence-specific DNA binding
HMEEINBN_00470 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMEEINBN_00471 5.3e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMEEINBN_00472 4.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMEEINBN_00473 5.3e-131 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMEEINBN_00474 1e-70 lytE M LysM domain protein
HMEEINBN_00475 8.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
HMEEINBN_00476 4.7e-311 S Bacterial membrane protein, YfhO
HMEEINBN_00477 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMEEINBN_00478 1.3e-91 yvbG U UPF0056 membrane protein
HMEEINBN_00479 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMEEINBN_00480 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMEEINBN_00481 2.2e-73 rplI J binds to the 23S rRNA
HMEEINBN_00482 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMEEINBN_00483 1.8e-47 veg S Biofilm formation stimulator VEG
HMEEINBN_00484 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMEEINBN_00485 1.9e-10
HMEEINBN_00486 5.4e-54 ypaA M Membrane
HMEEINBN_00487 9.3e-95 XK27_06935 K transcriptional regulator
HMEEINBN_00488 7.3e-160 XK27_06930 V domain protein
HMEEINBN_00489 4.4e-107 S Putative adhesin
HMEEINBN_00490 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
HMEEINBN_00491 6.3e-54 K transcriptional regulator, PadR family
HMEEINBN_00492 7e-115 nudL L hydrolase
HMEEINBN_00497 0.0
HMEEINBN_00498 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
HMEEINBN_00499 2.2e-148 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HMEEINBN_00501 5.8e-162 T Diguanylate cyclase
HMEEINBN_00502 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMEEINBN_00503 1.8e-60 fruR K transcriptional
HMEEINBN_00504 6e-13 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMEEINBN_00505 1.6e-129 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
HMEEINBN_00506 1.2e-94 tnp* L An automated process has identified a potential problem with this gene model
HMEEINBN_00507 1.7e-218 KLT Protein tyrosine kinase
HMEEINBN_00508 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMEEINBN_00509 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMEEINBN_00510 1.5e-219 metE 2.1.1.14 E Methionine synthase
HMEEINBN_00511 4.6e-118 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMEEINBN_00512 9e-31 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMEEINBN_00513 5.6e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMEEINBN_00515 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMEEINBN_00516 3.2e-167 XK27_01785 S cog cog1284
HMEEINBN_00517 1.6e-123 yaaA S Belongs to the UPF0246 family
HMEEINBN_00518 2.4e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMEEINBN_00519 2.4e-89 XK27_10930 K acetyltransferase
HMEEINBN_00520 1.7e-13
HMEEINBN_00521 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMEEINBN_00522 1.1e-287 ccs S the current gene model (or a revised gene model) may contain a frame shift
HMEEINBN_00523 3.2e-44 yrzB S Belongs to the UPF0473 family
HMEEINBN_00524 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMEEINBN_00525 6.3e-44 yrzL S Belongs to the UPF0297 family
HMEEINBN_00526 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMEEINBN_00527 3.7e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HMEEINBN_00529 6.5e-90 adk 2.7.4.3 F topology modulation protein
HMEEINBN_00530 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMEEINBN_00531 3.2e-77 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMEEINBN_00532 9.7e-36 XK27_09805 S MORN repeat protein
HMEEINBN_00533 0.0 XK27_09800 I Acyltransferase
HMEEINBN_00534 3.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMEEINBN_00535 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HMEEINBN_00536 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMEEINBN_00537 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
HMEEINBN_00538 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMEEINBN_00539 1.2e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMEEINBN_00540 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMEEINBN_00541 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMEEINBN_00542 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMEEINBN_00543 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMEEINBN_00544 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HMEEINBN_00545 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMEEINBN_00546 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMEEINBN_00547 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMEEINBN_00548 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMEEINBN_00549 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMEEINBN_00550 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMEEINBN_00551 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMEEINBN_00552 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMEEINBN_00553 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMEEINBN_00554 1.9e-23 rpmD J ribosomal protein l30
HMEEINBN_00555 5.7e-58 rplO J binds to the 23S rRNA
HMEEINBN_00556 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMEEINBN_00557 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMEEINBN_00558 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMEEINBN_00559 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMEEINBN_00560 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMEEINBN_00561 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMEEINBN_00562 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMEEINBN_00563 4.4e-62 rplQ J ribosomal protein l17
HMEEINBN_00564 8.7e-240 6.3.2.2 H gamma-glutamylcysteine synthetase
HMEEINBN_00566 3.1e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
HMEEINBN_00569 2.5e-95 ywlG S Belongs to the UPF0340 family
HMEEINBN_00570 3.9e-125 treR K trehalose operon
HMEEINBN_00571 2.8e-290 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMEEINBN_00572 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HMEEINBN_00573 0.0 pepO 3.4.24.71 O Peptidase family M13
HMEEINBN_00574 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMEEINBN_00577 9.2e-278 thrC 4.2.3.1 E Threonine synthase
HMEEINBN_00578 1.6e-225 norN V Mate efflux family protein
HMEEINBN_00579 1.4e-57 asp S cog cog1302
HMEEINBN_00580 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
HMEEINBN_00581 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HMEEINBN_00582 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HMEEINBN_00583 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
HMEEINBN_00584 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMEEINBN_00585 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMEEINBN_00586 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMEEINBN_00587 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMEEINBN_00588 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMEEINBN_00589 1.5e-67 S cog cog4699
HMEEINBN_00590 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HMEEINBN_00591 9.8e-161 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HMEEINBN_00592 2.2e-43 comGC U Required for transformation and DNA binding
HMEEINBN_00593 8.4e-70 cglD NU Competence protein
HMEEINBN_00594 5.3e-15 NU Type II secretory pathway pseudopilin
HMEEINBN_00595 9.9e-71 comGF U Competence protein ComGF
HMEEINBN_00596 1.5e-12 comGF U Putative Competence protein ComGF
HMEEINBN_00597 3.8e-176 ytxK 2.1.1.72 L DNA methylase
HMEEINBN_00598 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMEEINBN_00599 8.8e-27 lanR K sequence-specific DNA binding
HMEEINBN_00600 1.4e-108 V CAAX protease self-immunity
HMEEINBN_00602 2.2e-93 S CAAX amino terminal protease family protein
HMEEINBN_00603 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMEEINBN_00604 4.8e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HMEEINBN_00605 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
HMEEINBN_00606 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMEEINBN_00607 2.6e-09 S NTF2 fold immunity protein
HMEEINBN_00608 2.5e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMEEINBN_00609 2e-186 yeeE S Sulphur transport
HMEEINBN_00610 8.3e-37 yeeD O sulfur carrier activity
HMEEINBN_00611 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMEEINBN_00612 3.3e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMEEINBN_00616 9.2e-158 rrmA 2.1.1.187 Q methyltransferase
HMEEINBN_00617 1.6e-137 S HAD hydrolase, family IA, variant
HMEEINBN_00618 1e-56 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMEEINBN_00619 1.3e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMEEINBN_00620 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMEEINBN_00621 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HMEEINBN_00622 6.7e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMEEINBN_00623 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMEEINBN_00624 1.8e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
HMEEINBN_00625 8.4e-137 fnt P Formate nitrite transporter
HMEEINBN_00626 2.1e-230 XK27_09615 C reductase
HMEEINBN_00627 3.1e-107 XK27_09620 S FMN reductase (NADPH) activity
HMEEINBN_00628 5e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HMEEINBN_00629 8.7e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
HMEEINBN_00630 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMEEINBN_00631 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
HMEEINBN_00632 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HMEEINBN_00633 1.2e-50 S Protein of unknown function (DUF3397)
HMEEINBN_00634 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMEEINBN_00635 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMEEINBN_00636 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HMEEINBN_00637 4.3e-272 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMEEINBN_00638 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HMEEINBN_00639 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
HMEEINBN_00640 2.4e-210 hpk9 2.7.13.3 T protein histidine kinase activity
HMEEINBN_00641 2.3e-224 fasC 2.7.13.3 T protein histidine kinase activity
HMEEINBN_00642 7.2e-130 fasA KT Response regulator of the LytR AlgR family
HMEEINBN_00643 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMEEINBN_00644 1.7e-262 argH 4.3.2.1 E Argininosuccinate lyase
HMEEINBN_00645 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMEEINBN_00646 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMEEINBN_00647 1.2e-151 jag S RNA-binding protein
HMEEINBN_00648 1.1e-104 K Transcriptional regulator
HMEEINBN_00649 2.8e-102 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HMEEINBN_00650 3.4e-14 rpmH J Ribosomal protein L34
HMEEINBN_00651 1.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMEEINBN_00652 3.6e-107 EGP Major facilitator Superfamily
HMEEINBN_00653 5.2e-72 copY K negative regulation of transcription, DNA-templated
HMEEINBN_00654 0.0 copA 3.6.3.54 P P-type ATPase
HMEEINBN_00655 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
HMEEINBN_00656 2.3e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMEEINBN_00657 1.3e-114 papP P ABC transporter (Permease
HMEEINBN_00658 3e-106 P ABC transporter (Permease
HMEEINBN_00659 2.2e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMEEINBN_00660 7.4e-155 cjaA ET ABC transporter substrate-binding protein
HMEEINBN_00664 4.3e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMEEINBN_00665 1e-114 ywaF S Integral membrane protein (intg_mem_TP0381)
HMEEINBN_00666 8.9e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMEEINBN_00667 3.6e-192 yjbB G Permeases of the major facilitator superfamily
HMEEINBN_00668 7.8e-152 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HMEEINBN_00669 1.7e-99 thiT S Thiamine transporter
HMEEINBN_00670 3.3e-62 yjqA S Bacterial PH domain
HMEEINBN_00671 8.7e-154 corA P CorA-like protein
HMEEINBN_00672 1.7e-258 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMEEINBN_00673 3.2e-145 L Integrase core domain protein
HMEEINBN_00674 2.3e-122 L Helix-turn-helix domain
HMEEINBN_00675 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMEEINBN_00676 3.7e-224 G COG0457 FOG TPR repeat
HMEEINBN_00677 1.2e-176 yubA S permease
HMEEINBN_00678 3.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HMEEINBN_00679 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HMEEINBN_00680 3.2e-124 ftsE D cell division ATP-binding protein FtsE
HMEEINBN_00681 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMEEINBN_00682 2.3e-201 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HMEEINBN_00683 3e-156 yjjH S Calcineurin-like phosphoesterase
HMEEINBN_00684 9.1e-133 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMEEINBN_00685 0.0 pacL 3.6.3.8 P cation transport ATPase
HMEEINBN_00686 2.9e-66 ywiB S Domain of unknown function (DUF1934)
HMEEINBN_00687 4e-148 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
HMEEINBN_00688 4.6e-146 yidA S hydrolases of the HAD superfamily
HMEEINBN_00689 2.3e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HMEEINBN_00690 4.3e-56 S Protein of unknown function (DUF454)
HMEEINBN_00691 2.3e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HMEEINBN_00692 1e-235 vicK 2.7.13.3 T Histidine kinase
HMEEINBN_00693 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMEEINBN_00694 6.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMEEINBN_00695 1.1e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMEEINBN_00696 3.7e-68 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HMEEINBN_00698 2e-11
HMEEINBN_00699 2.6e-190 XK27_10075 S abc transporter atp-binding protein
HMEEINBN_00700 0.0 V abc transporter atp-binding protein
HMEEINBN_00701 3.6e-297 V abc transporter atp-binding protein
HMEEINBN_00702 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HMEEINBN_00704 9.5e-286 S Protein of unknown function (DUF3114)
HMEEINBN_00705 3.2e-98 2.3.1.128 K Acetyltransferase GNAT Family
HMEEINBN_00706 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMEEINBN_00707 9.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMEEINBN_00708 6.1e-181 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
HMEEINBN_00709 4e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMEEINBN_00710 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMEEINBN_00711 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMEEINBN_00712 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMEEINBN_00713 1.1e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HMEEINBN_00714 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMEEINBN_00715 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMEEINBN_00718 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMEEINBN_00719 1.9e-170 vraS 2.7.13.3 T Histidine kinase
HMEEINBN_00720 3.3e-116 yvqF S Membrane
HMEEINBN_00721 5.9e-103 kcsA P Ion transport protein
HMEEINBN_00722 2.3e-294 prkC 2.7.11.1 KLT serine threonine protein kinase
HMEEINBN_00723 1.3e-134 stp 3.1.3.16 T phosphatase
HMEEINBN_00724 2.7e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMEEINBN_00725 3.1e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMEEINBN_00726 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMEEINBN_00727 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HMEEINBN_00728 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HMEEINBN_00729 7e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMEEINBN_00730 3.5e-146 XK27_02985 S overlaps another CDS with the same product name
HMEEINBN_00731 2.6e-146 supH S overlaps another CDS with the same product name
HMEEINBN_00732 5.6e-62 yvoA_1 K Transcriptional
HMEEINBN_00733 4.1e-119 skfE V abc transporter atp-binding protein
HMEEINBN_00734 4.5e-130 V Psort location CytoplasmicMembrane, score
HMEEINBN_00735 4.7e-171 oppF P Belongs to the ABC transporter superfamily
HMEEINBN_00736 8.7e-201 oppD P Belongs to the ABC transporter superfamily
HMEEINBN_00737 3.1e-167 amiD P ABC transporter (Permease
HMEEINBN_00738 7.1e-278 amiC P ABC transporter (Permease
HMEEINBN_00739 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
HMEEINBN_00740 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HMEEINBN_00741 4.7e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HMEEINBN_00742 3.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HMEEINBN_00743 1.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMEEINBN_00744 1.1e-118 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HMEEINBN_00745 2.4e-101 yjbK S Adenylate cyclase
HMEEINBN_00746 1.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMEEINBN_00747 5.1e-204 iscS 2.8.1.7 E Cysteine desulfurase
HMEEINBN_00748 5.3e-59 XK27_04120 S Putative amino acid metabolism
HMEEINBN_00749 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMEEINBN_00750 8.2e-128 puuD T peptidase C26
HMEEINBN_00751 2.3e-114 radC E Belongs to the UPF0758 family
HMEEINBN_00752 8e-299 rgpF M Rhamnan synthesis protein F
HMEEINBN_00753 8.1e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMEEINBN_00754 6.8e-142 rgpC GM Transport permease protein
HMEEINBN_00755 1.9e-175 rgpB GT2 M Glycosyltransferase, group 2 family protein
HMEEINBN_00756 1.2e-224 rgpA GT4 M Domain of unknown function (DUF1972)
HMEEINBN_00757 3.1e-257 S Glucosyl transferase GtrII
HMEEINBN_00758 1.3e-227 GT4 M transferase activity, transferring glycosyl groups
HMEEINBN_00759 3e-221 M Psort location CytoplasmicMembrane, score
HMEEINBN_00760 0.0 rgpF GT2,GT4 M Rhamnan synthesis protein F
HMEEINBN_00761 3.7e-110
HMEEINBN_00762 1.3e-150 2.4.1.60 S Glycosyltransferase group 2 family protein
HMEEINBN_00763 3.2e-43 S Uncharacterized conserved protein (DUF2304)
HMEEINBN_00764 3.2e-127 arnC M group 2 family protein
HMEEINBN_00765 2.4e-141 M Glycosyl transferase family 8
HMEEINBN_00766 2.9e-166 amrA S polysaccharide biosynthetic process
HMEEINBN_00767 3.8e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMEEINBN_00768 6.1e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HMEEINBN_00769 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HMEEINBN_00770 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMEEINBN_00771 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMEEINBN_00772 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMEEINBN_00773 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMEEINBN_00774 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
HMEEINBN_00775 2e-200 arcT 2.6.1.1 E Aminotransferase
HMEEINBN_00776 2.1e-135 ET Belongs to the bacterial solute-binding protein 3 family
HMEEINBN_00777 1.9e-139 ET ABC transporter
HMEEINBN_00778 1.1e-80 mutT 3.6.1.55 F Nudix family
HMEEINBN_00779 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMEEINBN_00781 7.1e-167 S CAAX amino terminal protease family protein
HMEEINBN_00782 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HMEEINBN_00783 3.9e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMEEINBN_00784 1.7e-17 XK27_00735
HMEEINBN_00785 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMEEINBN_00787 5.8e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMEEINBN_00788 9.8e-10 O ADP-ribosylglycohydrolase
HMEEINBN_00789 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
HMEEINBN_00790 3.5e-61 ycaO O OsmC-like protein
HMEEINBN_00792 3.6e-152 EG Permeases of the drug metabolite transporter (DMT) superfamily
HMEEINBN_00793 2.5e-07 N PFAM Uncharacterised protein family UPF0150
HMEEINBN_00794 4.1e-113 serB 3.1.3.3 E phosphoserine phosphatase
HMEEINBN_00795 7.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMEEINBN_00796 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMEEINBN_00797 1.3e-94 3.1.3.18 S IA, variant 1
HMEEINBN_00798 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HMEEINBN_00799 1e-55 lrgA S Effector of murein hydrolase LrgA
HMEEINBN_00801 1.6e-58 arsC 1.20.4.1 P Belongs to the ArsC family
HMEEINBN_00802 1.3e-71 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HMEEINBN_00803 2.2e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMEEINBN_00804 2.5e-103 wecD M Acetyltransferase (GNAT) domain
HMEEINBN_00805 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMEEINBN_00806 5.4e-156 GK ROK family
HMEEINBN_00807 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
HMEEINBN_00808 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
HMEEINBN_00809 4.4e-205 potD P spermidine putrescine ABC transporter
HMEEINBN_00810 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
HMEEINBN_00811 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
HMEEINBN_00812 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMEEINBN_00813 1.4e-167 murB 1.3.1.98 M cell wall formation
HMEEINBN_00814 8.2e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HMEEINBN_00815 1.3e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMEEINBN_00816 3.5e-290 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HMEEINBN_00817 4.5e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HMEEINBN_00818 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
HMEEINBN_00819 0.0 ydaO E amino acid
HMEEINBN_00820 1e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMEEINBN_00821 1.5e-36 ylqC L Belongs to the UPF0109 family
HMEEINBN_00822 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMEEINBN_00824 6.2e-201 2.7.13.3 T protein histidine kinase activity
HMEEINBN_00825 7.6e-124 agrA KT phosphorelay signal transduction system
HMEEINBN_00826 3.9e-163 O protein import
HMEEINBN_00827 3.6e-165 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HMEEINBN_00828 3.7e-17 yjdB S Domain of unknown function (DUF4767)
HMEEINBN_00829 3.1e-62 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMEEINBN_00831 9.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HMEEINBN_00832 4.9e-71 S QueT transporter
HMEEINBN_00834 1.2e-169 yfjR K regulation of single-species biofilm formation
HMEEINBN_00836 2.4e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HMEEINBN_00837 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMEEINBN_00838 3.7e-85 ccl S cog cog4708
HMEEINBN_00839 8.4e-160 rbn E Belongs to the UPF0761 family
HMEEINBN_00840 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HMEEINBN_00841 1.9e-231 ytoI K transcriptional regulator containing CBS domains
HMEEINBN_00842 1.2e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HMEEINBN_00843 1.5e-228 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMEEINBN_00844 3.1e-306 comEC S Competence protein ComEC
HMEEINBN_00845 7.1e-69 comEC S Competence protein ComEC
HMEEINBN_00846 3.7e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HMEEINBN_00847 1.7e-142 plsC 2.3.1.51 I Acyltransferase
HMEEINBN_00848 4.5e-137 nodB3 G deacetylase
HMEEINBN_00849 3.3e-138 yabB 2.1.1.223 L Methyltransferase
HMEEINBN_00850 1.9e-40 yazA L endonuclease containing a URI domain
HMEEINBN_00851 8.7e-123 XK27_00785 S CAAX protease self-immunity
HMEEINBN_00852 1.8e-238 EGP Major facilitator Superfamily
HMEEINBN_00853 6.2e-67 rmaI K Transcriptional regulator, MarR family
HMEEINBN_00854 6.1e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
HMEEINBN_00855 3.1e-133 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
HMEEINBN_00856 0.0 3.5.1.28 M domain protein
HMEEINBN_00857 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMEEINBN_00858 5.4e-24
HMEEINBN_00861 2.3e-50 ywrO S general stress protein
HMEEINBN_00862 3.9e-154 K sequence-specific DNA binding
HMEEINBN_00863 2.2e-77 3.4.21.89 S RDD family
HMEEINBN_00864 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
HMEEINBN_00865 3.4e-147 sdaAA 4.3.1.17 E L-serine dehydratase
HMEEINBN_00866 6.1e-120 sdaAB 4.3.1.17 E L-serine dehydratase
HMEEINBN_00867 1.5e-18 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HMEEINBN_00868 3.2e-98 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HMEEINBN_00869 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMEEINBN_00870 1.5e-36 L RePlication protein
HMEEINBN_00871 2.6e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HMEEINBN_00872 1.8e-279 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HMEEINBN_00873 2.2e-163 L PFAM Integrase catalytic region
HMEEINBN_00874 1.8e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMEEINBN_00875 5.2e-87 pat 2.3.1.183 M acetyltransferase
HMEEINBN_00876 6.3e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMEEINBN_00877 4.8e-122 alkD L Dna alkylation repair
HMEEINBN_00878 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMEEINBN_00879 1.7e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMEEINBN_00880 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMEEINBN_00881 0.0 smc D Required for chromosome condensation and partitioning
HMEEINBN_00882 1.1e-90 S Protein of unknown function (DUF3278)
HMEEINBN_00883 3.8e-22 WQ51_00220 K Helix-turn-helix domain
HMEEINBN_00884 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMEEINBN_00885 1.5e-50 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMEEINBN_00886 3.3e-34 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMEEINBN_00887 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMEEINBN_00889 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HMEEINBN_00890 7.9e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMEEINBN_00892 2.2e-85 S ECF-type riboflavin transporter, S component
HMEEINBN_00893 2.6e-152 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HMEEINBN_00894 2.8e-83 XK27_01265 S ECF-type riboflavin transporter, S component
HMEEINBN_00895 4.3e-294 yfmM S abc transporter atp-binding protein
HMEEINBN_00896 1.4e-256 noxE P NADH oxidase
HMEEINBN_00897 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMEEINBN_00898 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMEEINBN_00899 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HMEEINBN_00900 9.1e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
HMEEINBN_00901 7.6e-164 ypuA S secreted protein
HMEEINBN_00902 6.1e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
HMEEINBN_00903 4.4e-45 rpmE2 J 50S ribosomal protein L31
HMEEINBN_00904 4.6e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMEEINBN_00905 6.5e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HMEEINBN_00906 1.1e-152 gst O Glutathione S-transferase
HMEEINBN_00907 1.8e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HMEEINBN_00908 3e-110 tdk 2.7.1.21 F thymidine kinase
HMEEINBN_00909 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMEEINBN_00910 3.9e-140 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMEEINBN_00911 1.4e-104 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMEEINBN_00912 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMEEINBN_00913 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
HMEEINBN_00914 9.2e-99 pvaA M lytic transglycosylase activity
HMEEINBN_00915 3.8e-291 yfiB1 V abc transporter atp-binding protein
HMEEINBN_00916 0.0 XK27_10035 V abc transporter atp-binding protein
HMEEINBN_00917 4.2e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMEEINBN_00918 1.2e-235 dltB M Membrane protein involved in D-alanine export
HMEEINBN_00919 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMEEINBN_00920 1.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMEEINBN_00921 0.0 3.6.3.8 P cation transport ATPase
HMEEINBN_00922 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HMEEINBN_00924 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMEEINBN_00925 7.3e-166 metF 1.5.1.20 E reductase
HMEEINBN_00926 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HMEEINBN_00927 2.9e-91 panT S Psort location CytoplasmicMembrane, score
HMEEINBN_00928 1.4e-93 panT S ECF transporter, substrate-specific component
HMEEINBN_00929 1.1e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMEEINBN_00930 6.9e-111 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HMEEINBN_00931 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMEEINBN_00932 6.1e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMEEINBN_00933 9.8e-237 T PhoQ Sensor
HMEEINBN_00934 1e-29 rpsT J Binds directly to 16S ribosomal RNA
HMEEINBN_00935 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
HMEEINBN_00936 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
HMEEINBN_00937 3e-232 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HMEEINBN_00938 3.9e-108 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMEEINBN_00939 2.2e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HMEEINBN_00940 8.3e-188 tcsA S membrane
HMEEINBN_00941 1.6e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HMEEINBN_00942 2.6e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
HMEEINBN_00943 1.7e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HMEEINBN_00944 1.7e-119 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HMEEINBN_00945 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMEEINBN_00946 1.1e-81 ypmB S Protein conserved in bacteria
HMEEINBN_00947 3.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HMEEINBN_00948 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HMEEINBN_00949 7.4e-20
HMEEINBN_00950 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
HMEEINBN_00951 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HMEEINBN_00952 1.7e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HMEEINBN_00953 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HMEEINBN_00954 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HMEEINBN_00955 3.7e-200 D nuclear chromosome segregation
HMEEINBN_00956 2.9e-134 yejC S cyclic nucleotide-binding protein
HMEEINBN_00957 2.2e-162 rapZ S Displays ATPase and GTPase activities
HMEEINBN_00958 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMEEINBN_00959 2.2e-160 whiA K May be required for sporulation
HMEEINBN_00960 3.6e-276 pepD E Dipeptidase
HMEEINBN_00961 7.9e-146 XK27_10720 D peptidase activity
HMEEINBN_00962 8.1e-285 adcA P Belongs to the bacterial solute-binding protein 9 family
HMEEINBN_00963 2.6e-09
HMEEINBN_00965 3.1e-168 yeiH S Membrane
HMEEINBN_00966 2.7e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
HMEEINBN_00967 8.4e-165 cpsY K Transcriptional regulator
HMEEINBN_00968 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMEEINBN_00969 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
HMEEINBN_00970 3.1e-105 artQ P ABC transporter (Permease
HMEEINBN_00971 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMEEINBN_00972 1.3e-156 aatB ET ABC transporter substrate-binding protein
HMEEINBN_00973 1.1e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMEEINBN_00974 2.6e-51
HMEEINBN_00975 1e-44
HMEEINBN_00976 4.6e-188 adhP 1.1.1.1 C alcohol dehydrogenase
HMEEINBN_00977 1.8e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMEEINBN_00978 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMEEINBN_00979 8.5e-125 gntR1 K transcriptional
HMEEINBN_00980 4.9e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMEEINBN_00981 8.5e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMEEINBN_00982 5.3e-87
HMEEINBN_00983 7.5e-86 niaR S small molecule binding protein (contains 3H domain)
HMEEINBN_00984 4e-127 K DNA-binding helix-turn-helix protein
HMEEINBN_00985 3.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMEEINBN_00986 3.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMEEINBN_00987 1e-165 GK ROK family
HMEEINBN_00988 2.3e-156 dprA LU DNA protecting protein DprA
HMEEINBN_00989 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMEEINBN_00990 2.2e-151 S TraX protein
HMEEINBN_00991 1.9e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMEEINBN_00992 2e-242 T PhoQ Sensor
HMEEINBN_00993 9e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMEEINBN_00994 8e-221 XK27_05470 E Methionine synthase
HMEEINBN_00995 7.2e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HMEEINBN_00996 2.2e-45 pspE P Rhodanese-like protein
HMEEINBN_00997 8.2e-137 IQ Acetoin reductase
HMEEINBN_00999 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMEEINBN_01002 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HMEEINBN_01003 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HMEEINBN_01004 4.4e-26 C Pyridoxamine 5'-phosphate oxidase
HMEEINBN_01005 1.1e-97 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HMEEINBN_01006 2.5e-77 S Macro domain
HMEEINBN_01007 1.1e-67 mgrA K Transcriptional regulator, MarR family
HMEEINBN_01008 9.1e-145 1.6.5.2 GM NmrA-like family
HMEEINBN_01009 3.5e-129 proV E abc transporter atp-binding protein
HMEEINBN_01010 1e-263 proWX P ABC transporter
HMEEINBN_01011 5.9e-109 magIII L Base excision DNA repair protein, HhH-GPD family
HMEEINBN_01012 0.0 V ABC transporter (Permease
HMEEINBN_01013 8.6e-125 V abc transporter atp-binding protein
HMEEINBN_01014 7.4e-92 tetR K transcriptional regulator
HMEEINBN_01015 8.5e-137 S Phenazine biosynthesis protein
HMEEINBN_01016 2.8e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
HMEEINBN_01017 7.4e-133 cbiQ P cobalt transport
HMEEINBN_01018 1.1e-155 P ATPase activity
HMEEINBN_01019 1.4e-150 cbiO2 P Zeta toxin
HMEEINBN_01020 4.9e-148 ycgQ S TIGR03943 family
HMEEINBN_01021 5.4e-156 XK27_03015 S permease
HMEEINBN_01023 0.0 yhgF K Transcriptional accessory protein
HMEEINBN_01024 3.9e-83 ydcK S Belongs to the SprT family
HMEEINBN_01025 2.2e-41 pspC KT PspC domain
HMEEINBN_01026 3.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMEEINBN_01027 2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMEEINBN_01028 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMEEINBN_01029 1.9e-66 ytxH S General stress protein
HMEEINBN_01031 8.9e-178 yegQ O Peptidase U32
HMEEINBN_01032 7.5e-252 yegQ O Peptidase U32
HMEEINBN_01033 3e-85 bioY S biotin synthase
HMEEINBN_01035 1.1e-33 XK27_12190 S protein conserved in bacteria
HMEEINBN_01036 5.1e-300 S dextransucrase activity
HMEEINBN_01037 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HMEEINBN_01038 7.8e-103 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HMEEINBN_01039 0.0 S dextransucrase activity
HMEEINBN_01040 1.6e-240 tcdB S dextransucrase activity
HMEEINBN_01041 2.3e-76 S dextransucrase activity
HMEEINBN_01042 0.0 M domain protein
HMEEINBN_01044 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMEEINBN_01045 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMEEINBN_01046 2e-178 XK27_08075 M glycosyl transferase family 2
HMEEINBN_01047 2.2e-94 S Carbohydrate-binding domain-containing protein Cthe_2159
HMEEINBN_01048 2.4e-144 P molecular chaperone
HMEEINBN_01049 1.8e-95 XK27_05505 S Psort location CytoplasmicMembrane, score
HMEEINBN_01051 3.4e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HMEEINBN_01052 4.7e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMEEINBN_01053 8.9e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMEEINBN_01054 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMEEINBN_01055 2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMEEINBN_01056 2.6e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HMEEINBN_01057 1e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMEEINBN_01058 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMEEINBN_01059 4.5e-180 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMEEINBN_01060 7.2e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMEEINBN_01061 3.7e-61 XK27_08085
HMEEINBN_01062 1.2e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HMEEINBN_01063 2.3e-136 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HMEEINBN_01064 4.3e-115 ylfI S tigr01906
HMEEINBN_01065 1.5e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMEEINBN_01066 2.9e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
HMEEINBN_01067 2.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
HMEEINBN_01068 1.7e-30 KT response to antibiotic
HMEEINBN_01070 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMEEINBN_01071 7e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HMEEINBN_01072 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMEEINBN_01073 3.1e-256 S phospholipase Carboxylesterase
HMEEINBN_01074 1.4e-195 yurR 1.4.5.1 E oxidoreductase
HMEEINBN_01075 4.4e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
HMEEINBN_01076 1.9e-144 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMEEINBN_01077 8.1e-120 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMEEINBN_01078 1.3e-64 gtrA S GtrA-like protein
HMEEINBN_01079 4.8e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMEEINBN_01080 3.8e-163 ybbR S Protein conserved in bacteria
HMEEINBN_01081 1.8e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMEEINBN_01082 6.4e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HMEEINBN_01083 1.4e-147 cobQ S glutamine amidotransferase
HMEEINBN_01084 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMEEINBN_01085 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
HMEEINBN_01086 2.7e-39 MA20_06245 S yiaA/B two helix domain
HMEEINBN_01087 0.0 uup S abc transporter atp-binding protein
HMEEINBN_01088 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HMEEINBN_01089 5.1e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
HMEEINBN_01090 3.2e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
HMEEINBN_01091 2.7e-153 XK27_05675 S Esterase
HMEEINBN_01092 3.9e-161 XK27_05670 S Putative esterase
HMEEINBN_01093 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HMEEINBN_01094 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMEEINBN_01095 3e-38 ptsH G phosphocarrier protein Hpr
HMEEINBN_01096 8.8e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
HMEEINBN_01097 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HMEEINBN_01098 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HMEEINBN_01099 2.2e-34 nrdH O Glutaredoxin
HMEEINBN_01100 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMEEINBN_01101 4.2e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMEEINBN_01102 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMEEINBN_01103 8.4e-138 divIVA D Cell division initiation protein
HMEEINBN_01104 2.7e-143 ylmH S conserved protein, contains S4-like domain
HMEEINBN_01105 5e-30 yggT D integral membrane protein
HMEEINBN_01106 2.2e-86 sepF D cell septum assembly
HMEEINBN_01107 3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HMEEINBN_01108 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMEEINBN_01109 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMEEINBN_01110 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMEEINBN_01111 7.3e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMEEINBN_01112 7.4e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMEEINBN_01114 0.0 typA T GTP-binding protein TypA
HMEEINBN_01115 2.7e-177 glk 2.7.1.2 G Glucokinase
HMEEINBN_01116 7.1e-27 yqgQ S protein conserved in bacteria
HMEEINBN_01117 3.4e-79 perR P Belongs to the Fur family
HMEEINBN_01118 1.1e-89 dps P Belongs to the Dps family
HMEEINBN_01119 2.9e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HMEEINBN_01120 1.1e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HMEEINBN_01121 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HMEEINBN_01122 5.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HMEEINBN_01123 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HMEEINBN_01124 2.1e-64 S Domain of unknown function (DUF4430)
HMEEINBN_01125 2.1e-74 S Psort location CytoplasmicMembrane, score
HMEEINBN_01126 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
HMEEINBN_01127 8.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
HMEEINBN_01128 3.3e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
HMEEINBN_01129 9.1e-113 sirR K iron dependent repressor
HMEEINBN_01130 3.4e-134 htpX O Belongs to the peptidase M48B family
HMEEINBN_01131 1.1e-90 lemA S LemA family
HMEEINBN_01132 6e-172 spd F DNA RNA non-specific endonuclease
HMEEINBN_01133 0.0 2.4.1.21 GT5 M Right handed beta helix region
HMEEINBN_01134 2.9e-133 S double-stranded DNA endodeoxyribonuclease activity
HMEEINBN_01135 6.7e-193 higA K Pfam:DUF955
HMEEINBN_01136 1.7e-54
HMEEINBN_01137 9.1e-58
HMEEINBN_01138 1.7e-135
HMEEINBN_01139 3.4e-137 3.1.21.3 V Type I restriction modification DNA specificity domain
HMEEINBN_01140 2.1e-280 hsdM 2.1.1.72 V type I restriction-modification system
HMEEINBN_01141 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
HMEEINBN_01142 7.9e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMEEINBN_01143 4e-212 MA20_36090 S Protein of unknown function (DUF2974)
HMEEINBN_01144 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMEEINBN_01145 2.1e-157 5.2.1.8 G hydrolase
HMEEINBN_01146 1.3e-26 P Hemerythrin HHE cation binding domain protein
HMEEINBN_01147 1.9e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
HMEEINBN_01148 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMEEINBN_01149 7.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
HMEEINBN_01150 5.2e-175 S hydrolase
HMEEINBN_01151 3.8e-23
HMEEINBN_01152 2.2e-137 M LysM domain
HMEEINBN_01153 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMEEINBN_01154 2.2e-14
HMEEINBN_01155 3.9e-13
HMEEINBN_01156 3.6e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HMEEINBN_01157 0.0 lpdA 1.8.1.4 C Dehydrogenase
HMEEINBN_01158 0.0 3.5.1.28 NU amidase activity
HMEEINBN_01159 9.3e-159 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
HMEEINBN_01160 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMEEINBN_01161 4e-45 ftsL D cell division protein FtsL
HMEEINBN_01162 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HMEEINBN_01163 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMEEINBN_01164 1.3e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMEEINBN_01166 1.2e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMEEINBN_01167 2e-60 yutD J protein conserved in bacteria
HMEEINBN_01168 3.9e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HMEEINBN_01169 1.8e-90 XK27_09885 V Glycopeptide antibiotics resistance protein
HMEEINBN_01172 0.0 mdlA V abc transporter atp-binding protein
HMEEINBN_01173 0.0 mdlB V abc transporter atp-binding protein
HMEEINBN_01174 4e-10 S Bacteriocin class II with double-glycine leader peptide
HMEEINBN_01180 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMEEINBN_01181 1.2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HMEEINBN_01182 4.5e-107 V CAAX protease self-immunity
HMEEINBN_01183 3.2e-141 cppA E CppA N-terminal
HMEEINBN_01184 6.9e-170 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HMEEINBN_01186 5.3e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMEEINBN_01187 2.7e-143 cah 4.2.1.1 P carbonic anhydrase
HMEEINBN_01188 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HMEEINBN_01189 1.1e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMEEINBN_01190 6.1e-35
HMEEINBN_01191 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMEEINBN_01192 3.3e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMEEINBN_01193 2.3e-162 yxeN P ABC transporter (Permease
HMEEINBN_01194 9.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
HMEEINBN_01195 5e-10 S Protein of unknown function (DUF4059)
HMEEINBN_01196 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMEEINBN_01197 1.3e-91 rsmD 2.1.1.171 L Methyltransferase
HMEEINBN_01198 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMEEINBN_01199 3.2e-187 ylbL T Belongs to the peptidase S16 family
HMEEINBN_01200 5.4e-183 yhcC S radical SAM protein
HMEEINBN_01201 2.7e-97 ytqB J (SAM)-dependent
HMEEINBN_01203 0.0 yjcE P NhaP-type Na H and K H antiporters
HMEEINBN_01204 5.6e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HMEEINBN_01205 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HMEEINBN_01206 7.4e-10 MU outer membrane autotransporter barrel domain protein
HMEEINBN_01207 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMEEINBN_01209 9e-75 XK27_03180 T universal stress protein
HMEEINBN_01210 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HMEEINBN_01211 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HMEEINBN_01212 8.3e-99 pncA Q isochorismatase
HMEEINBN_01213 2.6e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMEEINBN_01214 6.7e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HMEEINBN_01215 9.7e-158 H COG0463 Glycosyltransferases involved in cell wall biogenesis
HMEEINBN_01216 1.6e-188 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HMEEINBN_01217 3.1e-233 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HMEEINBN_01218 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMEEINBN_01219 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMEEINBN_01220 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMEEINBN_01222 2.7e-282 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMEEINBN_01223 1.2e-36 S Sulfite exporter TauE/SafE
HMEEINBN_01224 7.2e-31 S PQ loop repeat
HMEEINBN_01225 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
HMEEINBN_01226 2.2e-279 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
HMEEINBN_01227 8.5e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
HMEEINBN_01228 1.5e-57
HMEEINBN_01229 8.2e-217 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMEEINBN_01230 1.1e-60
HMEEINBN_01231 1.5e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HMEEINBN_01232 8.2e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HMEEINBN_01233 5.1e-98 yqeG S hydrolase of the HAD superfamily
HMEEINBN_01234 1.6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HMEEINBN_01235 7.7e-49 yhbY J RNA-binding protein
HMEEINBN_01236 2.3e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMEEINBN_01237 7.8e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HMEEINBN_01238 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMEEINBN_01239 8.4e-139 yqeM Q Methyltransferase domain protein
HMEEINBN_01240 2.9e-196 ylbM S Belongs to the UPF0348 family
HMEEINBN_01241 3.4e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HMEEINBN_01242 1.6e-44 yoeB S Addiction module toxin, Txe YoeB family
HMEEINBN_01243 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
HMEEINBN_01245 1.6e-103
HMEEINBN_01248 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HMEEINBN_01249 2.2e-131 ecsA V abc transporter atp-binding protein
HMEEINBN_01250 3.2e-176 ecsB U Bacterial ABC transporter protein EcsB
HMEEINBN_01251 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
HMEEINBN_01252 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMEEINBN_01254 2.1e-213 ytfP S Flavoprotein
HMEEINBN_01255 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HMEEINBN_01256 9.6e-64 XK27_02560 S cog cog2151
HMEEINBN_01257 2.6e-41 WQ51_02910 S Protein of unknown function, DUF536
HMEEINBN_01258 6.4e-105 dnaQ 2.7.7.7 L DNA polymerase III
HMEEINBN_01259 3.1e-125 K transcriptional regulator, MerR family
HMEEINBN_01260 0.0 V ABC transporter (Permease
HMEEINBN_01261 1.6e-123 V abc transporter atp-binding protein
HMEEINBN_01263 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMEEINBN_01264 1.2e-189 L Pfam:Integrase_AP2
HMEEINBN_01265 8.4e-25 S Domain of unknown function (DUF3173)
HMEEINBN_01266 2.3e-205 S Replication initiation factor
HMEEINBN_01267 2.3e-120 D ftsk spoiiie
HMEEINBN_01271 1.8e-40 K Helix-turn-helix
HMEEINBN_01272 6.2e-79
HMEEINBN_01274 1.5e-49
HMEEINBN_01275 9e-47
HMEEINBN_01276 0.0 ctpE P E1-E2 ATPase
HMEEINBN_01277 7e-59
HMEEINBN_01278 2.6e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
HMEEINBN_01279 5.3e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMEEINBN_01280 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HMEEINBN_01281 1.1e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMEEINBN_01282 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HMEEINBN_01283 4.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HMEEINBN_01284 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMEEINBN_01285 7.8e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMEEINBN_01287 4.2e-54 EGP Major facilitator Superfamily
HMEEINBN_01289 1.1e-130 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
HMEEINBN_01290 2.3e-10 sraP UW domain, Protein
HMEEINBN_01291 2e-29 bipA S protein secretion
HMEEINBN_01292 6.8e-61 pdxH S pyridoxamine 5'-phosphate oxidase
HMEEINBN_01293 1.5e-242 norM V Multidrug efflux pump
HMEEINBN_01295 1e-181 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMEEINBN_01296 1.4e-229 brnQ E Component of the transport system for branched-chain amino acids
HMEEINBN_01297 1.1e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMEEINBN_01298 1.8e-59 S Protein of unknown function (DUF3290)
HMEEINBN_01299 1.5e-107 S Protein of unknown function (DUF421)
HMEEINBN_01300 1.4e-16 csbD S CsbD-like
HMEEINBN_01301 1.7e-107 S Carbohydrate-binding domain-containing protein Cthe_2159
HMEEINBN_01302 1.5e-50 XK27_01300 S ASCH
HMEEINBN_01303 7.2e-216 yfnA E amino acid
HMEEINBN_01304 0.0 S dextransucrase activity
HMEEINBN_01305 5.6e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HMEEINBN_01306 2e-42 S Sugar efflux transporter for intercellular exchange
HMEEINBN_01307 1.2e-203 P FtsX-like permease family
HMEEINBN_01308 1.3e-122 V abc transporter atp-binding protein
HMEEINBN_01309 6.9e-96 K WHG domain
HMEEINBN_01310 3.7e-168 ydhF S Aldo keto reductase
HMEEINBN_01311 1.1e-06 S Protein of unknown function (DUF3169)
HMEEINBN_01312 2.5e-27 XK27_07105 K transcriptional
HMEEINBN_01313 2.7e-27
HMEEINBN_01314 2.2e-108 XK27_02070 S nitroreductase
HMEEINBN_01315 1.4e-150 1.13.11.2 S glyoxalase
HMEEINBN_01316 2.5e-77 ywnA K Transcriptional regulator
HMEEINBN_01317 2.2e-154 E Alpha/beta hydrolase of unknown function (DUF915)
HMEEINBN_01318 3.6e-230 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMEEINBN_01319 2.4e-167 bcrA V abc transporter atp-binding protein
HMEEINBN_01320 5.8e-127 S ABC-2 family transporter protein
HMEEINBN_01321 1.5e-09
HMEEINBN_01322 6.7e-07 S Tetratricopeptide repeats
HMEEINBN_01325 1.2e-128 T PhoQ Sensor
HMEEINBN_01326 3.3e-121 T Xre family transcriptional regulator
HMEEINBN_01327 4.1e-110 drgA C nitroreductase
HMEEINBN_01328 1.6e-104 yoaK S Protein of unknown function (DUF1275)
HMEEINBN_01329 5.3e-40 DJ nuclease activity
HMEEINBN_01330 1.1e-30 XK27_10490
HMEEINBN_01331 7.1e-158 yvgN C reductase
HMEEINBN_01332 3.3e-75 S Tetratricopeptide repeat
HMEEINBN_01333 0.0 lacL 3.2.1.23 G -beta-galactosidase
HMEEINBN_01334 0.0 lacS G transporter
HMEEINBN_01335 1.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMEEINBN_01336 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMEEINBN_01337 1.8e-286 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HMEEINBN_01338 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMEEINBN_01339 7e-181 galR K Transcriptional regulator
HMEEINBN_01340 2.1e-307 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
HMEEINBN_01341 1.7e-222 vncS 2.7.13.3 T Histidine kinase
HMEEINBN_01342 2.2e-114 K Response regulator receiver domain protein
HMEEINBN_01343 1.1e-235 vex3 V Efflux ABC transporter, permease protein
HMEEINBN_01344 6.6e-108 vex2 V abc transporter atp-binding protein
HMEEINBN_01345 1.2e-180 vex1 V Efflux ABC transporter, permease protein
HMEEINBN_01346 3.3e-283 XK27_07020 S Belongs to the UPF0371 family
HMEEINBN_01348 2.2e-199 gldA 1.1.1.6 C glycerol dehydrogenase
HMEEINBN_01349 1.1e-178 XK27_10475 S oxidoreductase
HMEEINBN_01350 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
HMEEINBN_01351 1.2e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
HMEEINBN_01352 2.7e-177 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
HMEEINBN_01353 1.2e-225 thrE K Psort location CytoplasmicMembrane, score
HMEEINBN_01354 0.0 M Putative cell wall binding repeat
HMEEINBN_01355 9.3e-34 S Immunity protein 41
HMEEINBN_01356 0.0 pepO 3.4.24.71 O Peptidase family M13
HMEEINBN_01357 2.8e-09 S Enterocin A Immunity
HMEEINBN_01358 3.6e-196 mccF V LD-carboxypeptidase
HMEEINBN_01359 1.2e-15 S integral membrane protein
HMEEINBN_01360 2.5e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
HMEEINBN_01361 4.8e-118 yhfC S Putative membrane peptidase family (DUF2324)
HMEEINBN_01362 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMEEINBN_01364 8.1e-245 S dextransucrase activity
HMEEINBN_01365 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMEEINBN_01366 0.0 S dextransucrase activity
HMEEINBN_01367 9.5e-59 tcyB_2 P ABC transporter (permease)
HMEEINBN_01368 6.7e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMEEINBN_01369 2.4e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMEEINBN_01370 2.7e-207 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMEEINBN_01371 5.3e-74 L Transposase
HMEEINBN_01372 2.2e-143 L Transposase and inactivated derivatives
HMEEINBN_01373 6.6e-96
HMEEINBN_01376 5.5e-44 yhaI J Protein of unknown function (DUF805)
HMEEINBN_01377 3.4e-62 yhaI J Protein of unknown function (DUF805)
HMEEINBN_01378 3e-32 yhaI J Protein of unknown function (DUF805)
HMEEINBN_01379 3.2e-60 yhaI J Membrane
HMEEINBN_01380 3.5e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMEEINBN_01381 2.6e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMEEINBN_01382 6.8e-271 XK27_00765
HMEEINBN_01383 8.9e-133 ecsA_2 V abc transporter atp-binding protein
HMEEINBN_01384 3.1e-125 S Protein of unknown function (DUF554)
HMEEINBN_01385 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMEEINBN_01386 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HMEEINBN_01387 8e-244 2.7.13.3 T protein histidine kinase activity
HMEEINBN_01388 1.9e-234 dcuS 2.7.13.3 T protein histidine kinase activity
HMEEINBN_01389 5.8e-13
HMEEINBN_01392 5.8e-146 V Psort location CytoplasmicMembrane, score
HMEEINBN_01394 1.7e-298 O MreB/Mbl protein
HMEEINBN_01395 2.4e-119 liaI S membrane
HMEEINBN_01396 1.5e-74 XK27_02470 K LytTr DNA-binding domain protein
HMEEINBN_01397 6e-305 KT response to antibiotic
HMEEINBN_01398 8.8e-98 yebC M Membrane
HMEEINBN_01399 6.8e-259 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
HMEEINBN_01400 2.7e-177 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HMEEINBN_01402 2.9e-31 yozG K Transcriptional regulator
HMEEINBN_01406 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMEEINBN_01407 2.6e-200 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMEEINBN_01408 5.8e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMEEINBN_01409 2.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMEEINBN_01410 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMEEINBN_01411 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMEEINBN_01413 5.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMEEINBN_01414 3.8e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HMEEINBN_01415 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMEEINBN_01416 7.8e-290 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
HMEEINBN_01417 9.2e-178 scrR K Transcriptional regulator
HMEEINBN_01418 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMEEINBN_01419 1.7e-61 yqhY S protein conserved in bacteria
HMEEINBN_01420 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMEEINBN_01421 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
HMEEINBN_01422 7e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HMEEINBN_01423 4.7e-32 blpT
HMEEINBN_01427 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HMEEINBN_01428 1e-168 corA P COG0598 Mg2 and Co2 transporters
HMEEINBN_01429 1e-122 XK27_01040 S Protein of unknown function (DUF1129)
HMEEINBN_01431 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMEEINBN_01432 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMEEINBN_01433 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HMEEINBN_01434 3.8e-43 XK27_05745
HMEEINBN_01435 6.8e-220 mutY L A G-specific adenine glycosylase
HMEEINBN_01437 1.5e-35
HMEEINBN_01439 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMEEINBN_01440 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMEEINBN_01441 6.1e-94 cvpA S toxin biosynthetic process
HMEEINBN_01442 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMEEINBN_01443 5e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMEEINBN_01444 7.4e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMEEINBN_01445 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMEEINBN_01446 1.3e-46 azlD S branched-chain amino acid
HMEEINBN_01447 9.7e-113 azlC E AzlC protein
HMEEINBN_01448 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMEEINBN_01449 5.9e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HMEEINBN_01450 7.9e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HMEEINBN_01451 1.5e-33 ykzG S Belongs to the UPF0356 family
HMEEINBN_01452 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMEEINBN_01453 6.5e-224 L Transposase
HMEEINBN_01454 1.2e-180 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HMEEINBN_01455 2e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMEEINBN_01456 1.5e-86 ebsA S Family of unknown function (DUF5322)
HMEEINBN_01457 2.5e-17 M LysM domain
HMEEINBN_01458 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMEEINBN_01459 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMEEINBN_01460 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMEEINBN_01461 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMEEINBN_01462 2.5e-83 XK27_03610 K Gnat family
HMEEINBN_01463 1.2e-91 yybC
HMEEINBN_01464 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMEEINBN_01465 1.3e-273 pepV 3.5.1.18 E Dipeptidase
HMEEINBN_01466 5.5e-109 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMEEINBN_01467 1.2e-225 V Glucan-binding protein C
HMEEINBN_01468 3.7e-252 V Glucan-binding protein C
HMEEINBN_01469 4.3e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMEEINBN_01470 1.6e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMEEINBN_01471 5e-96 S Protein of unknown function (DUF1697)
HMEEINBN_01472 1.1e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HMEEINBN_01473 1.7e-171 clcA_2 P Chloride transporter, ClC family
HMEEINBN_01474 6.7e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
HMEEINBN_01475 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HMEEINBN_01476 3.6e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HMEEINBN_01477 2.6e-132 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HMEEINBN_01478 3.8e-109 cps4C M biosynthesis protein
HMEEINBN_01479 1.8e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
HMEEINBN_01480 4.7e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HMEEINBN_01481 1.8e-220 rgpAc GT4 M group 1 family protein
HMEEINBN_01482 4.4e-211 wcoF M Glycosyltransferase, group 1 family protein
HMEEINBN_01483 3.4e-120 Z012_10770 M Domain of unknown function (DUF1919)
HMEEINBN_01484 4e-165
HMEEINBN_01485 2.9e-164 M Glycosyltransferase like family 2
HMEEINBN_01486 1.7e-122 cps3F
HMEEINBN_01487 2.4e-243 epsU S Polysaccharide biosynthesis protein
HMEEINBN_01488 1.1e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
HMEEINBN_01489 2.7e-185 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
HMEEINBN_01490 3.8e-177 wbbI M transferase activity, transferring glycosyl groups
HMEEINBN_01492 3.6e-151 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HMEEINBN_01493 1.1e-107 pgm G Belongs to the phosphoglycerate mutase family
HMEEINBN_01494 1.1e-107 G Belongs to the phosphoglycerate mutase family
HMEEINBN_01495 1.3e-108 G Belongs to the phosphoglycerate mutase family
HMEEINBN_01496 5.2e-196 S hmm pf01594
HMEEINBN_01497 3.4e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMEEINBN_01498 4.9e-39 S granule-associated protein
HMEEINBN_01499 2.3e-287 S unusual protein kinase
HMEEINBN_01500 1.6e-98 estA E Lysophospholipase L1 and related esterases
HMEEINBN_01501 3.9e-156 rssA S Phospholipase, patatin family
HMEEINBN_01502 6.1e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HMEEINBN_01503 7.1e-245 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HMEEINBN_01504 2.8e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMEEINBN_01505 1.5e-118 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMEEINBN_01506 2.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMEEINBN_01507 0.0 S the current gene model (or a revised gene model) may contain a frame shift
HMEEINBN_01508 1.8e-224 2.7.13.3 T protein histidine kinase activity
HMEEINBN_01509 2.2e-203 hpk9 2.7.13.3 T protein histidine kinase activity
HMEEINBN_01510 5.6e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HMEEINBN_01511 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMEEINBN_01514 1.6e-163 ppaC 3.6.1.1 C inorganic pyrophosphatase
HMEEINBN_01515 5.6e-104 S Domain of unknown function (DUF1803)
HMEEINBN_01516 7.8e-102 ygaC J Belongs to the UPF0374 family
HMEEINBN_01517 8.3e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMEEINBN_01518 3.8e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMEEINBN_01519 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
HMEEINBN_01520 6.9e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMEEINBN_01521 1.8e-113 S HAD hydrolase, family IA, variant 3
HMEEINBN_01522 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HMEEINBN_01523 2e-71 marR K Transcriptional regulator, MarR family
HMEEINBN_01524 3.7e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMEEINBN_01525 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMEEINBN_01526 2.6e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HMEEINBN_01527 8.8e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HMEEINBN_01528 1.8e-125 IQ reductase
HMEEINBN_01529 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMEEINBN_01530 1.2e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMEEINBN_01531 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMEEINBN_01532 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HMEEINBN_01533 1e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMEEINBN_01534 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HMEEINBN_01535 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMEEINBN_01536 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
HMEEINBN_01537 4e-112 fruR K transcriptional
HMEEINBN_01538 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMEEINBN_01539 0.0 fruA 2.7.1.202 G phosphotransferase system
HMEEINBN_01540 5.5e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMEEINBN_01541 2.3e-229 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMEEINBN_01543 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HMEEINBN_01544 7.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMEEINBN_01545 1.3e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HMEEINBN_01546 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HMEEINBN_01547 9.6e-84 2.3.1.128 K acetyltransferase
HMEEINBN_01548 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMEEINBN_01549 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMEEINBN_01550 4.2e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMEEINBN_01551 5e-63 WQ51_03320 S cog cog4835
HMEEINBN_01552 1.3e-146 XK27_08360 S EDD domain protein, DegV family
HMEEINBN_01553 1.1e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMEEINBN_01554 1.7e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMEEINBN_01555 0.0 yfmR S abc transporter atp-binding protein
HMEEINBN_01556 5.9e-27 U response to pH
HMEEINBN_01557 1.6e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HMEEINBN_01558 4.7e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HMEEINBN_01560 1.5e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HMEEINBN_01561 2.8e-283 S Psort location CytoplasmicMembrane, score
HMEEINBN_01562 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMEEINBN_01563 4.4e-74 K DNA-binding transcription factor activity
HMEEINBN_01564 0.0 lmrA1 V abc transporter atp-binding protein
HMEEINBN_01565 0.0 lmrA2 V abc transporter atp-binding protein
HMEEINBN_01566 3.9e-113 K Acetyltransferase (GNAT) family
HMEEINBN_01567 5.7e-112 2.7.6.5 S Region found in RelA / SpoT proteins
HMEEINBN_01568 8.3e-117 T response regulator
HMEEINBN_01569 1.2e-211 sptS 2.7.13.3 T Histidine kinase
HMEEINBN_01570 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMEEINBN_01571 4.2e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMEEINBN_01572 1.3e-159 cvfB S Protein conserved in bacteria
HMEEINBN_01573 3.7e-34 yozE S Belongs to the UPF0346 family
HMEEINBN_01574 2.3e-123 sip M LysM domain protein
HMEEINBN_01575 3.1e-187 phoH T phosphate starvation-inducible protein PhoH
HMEEINBN_01576 2.9e-33 pnuC H nicotinamide mononucleotide transporter
HMEEINBN_01578 7.2e-67 S Protein of unknown function with HXXEE motif
HMEEINBN_01579 1.7e-96 K Transcriptional regulator, TetR family
HMEEINBN_01580 1e-154 czcD P cation diffusion facilitator family transporter
HMEEINBN_01581 1e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HMEEINBN_01582 3.4e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HMEEINBN_01583 3.7e-235 S the current gene model (or a revised gene model) may contain a frame shift
HMEEINBN_01584 5.4e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HMEEINBN_01585 6.6e-19 V Type III restriction enzyme, res subunit
HMEEINBN_01586 1.2e-106 V Type III restriction enzyme, res subunit
HMEEINBN_01587 1.5e-21 V Type III restriction enzyme, res subunit
HMEEINBN_01588 1.9e-170 P abc-type fe3 -hydroxamate transport system, periplasmic component
HMEEINBN_01589 2.4e-232 dinF V Mate efflux family protein
HMEEINBN_01590 2.3e-271 S Psort location CytoplasmicMembrane, score
HMEEINBN_01591 8.1e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HMEEINBN_01592 4.4e-133 S TraX protein
HMEEINBN_01593 1e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HMEEINBN_01594 5e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HMEEINBN_01595 1.4e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMEEINBN_01599 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMEEINBN_01600 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMEEINBN_01601 3.3e-240 nylA 3.5.1.4 J Belongs to the amidase family
HMEEINBN_01602 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
HMEEINBN_01603 2.4e-81 yecS P ABC transporter (Permease
HMEEINBN_01604 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HMEEINBN_01605 3.9e-176 bglC K Transcriptional regulator
HMEEINBN_01606 1.2e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMEEINBN_01607 2e-239 agcS E (Alanine) symporter
HMEEINBN_01608 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMEEINBN_01609 5e-240 metY 2.5.1.49 E o-acetylhomoserine
HMEEINBN_01610 2.8e-137 S haloacid dehalogenase-like hydrolase
HMEEINBN_01611 3.6e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMEEINBN_01612 4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HMEEINBN_01613 1e-34 M1-755 P Hemerythrin HHE cation binding domain protein
HMEEINBN_01614 1.4e-240 XK27_04775 S hemerythrin HHE cation binding domain
HMEEINBN_01615 1.1e-145 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMEEINBN_01616 8.7e-170 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMEEINBN_01617 2.1e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMEEINBN_01618 3e-44 yktA S Belongs to the UPF0223 family
HMEEINBN_01619 5.9e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HMEEINBN_01620 2.2e-246 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HMEEINBN_01621 3.1e-156 pstS P phosphate
HMEEINBN_01622 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HMEEINBN_01623 1.3e-154 pstA P phosphate transport system permease
HMEEINBN_01624 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMEEINBN_01625 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMEEINBN_01626 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
HMEEINBN_01627 0.0 pepN 3.4.11.2 E aminopeptidase
HMEEINBN_01628 3.5e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HMEEINBN_01629 0.0 K Probable Zinc-ribbon domain
HMEEINBN_01630 3.8e-99
HMEEINBN_01631 5.8e-143 L viral genome integration into host DNA
HMEEINBN_01635 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMEEINBN_01636 6.9e-161 S reductase
HMEEINBN_01637 4.7e-168 K transcriptional regulator (lysR family)
HMEEINBN_01638 5.5e-106 S CAAX amino terminal protease family protein
HMEEINBN_01639 4.1e-262 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HMEEINBN_01640 3.1e-165 coiA 3.6.4.12 S Competence protein
HMEEINBN_01641 0.0 pepF E oligoendopeptidase F
HMEEINBN_01642 8.5e-213 oxlT P COG0477 Permeases of the major facilitator superfamily
HMEEINBN_01643 6.7e-119 yrrM 2.1.1.104 S O-Methyltransferase
HMEEINBN_01644 1.1e-164 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HMEEINBN_01645 2.4e-81 yxjI S LURP-one-related
HMEEINBN_01646 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMEEINBN_01647 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HMEEINBN_01648 2e-132 agrA KT response regulator
HMEEINBN_01649 1.4e-229 2.7.13.3 T GHKL domain
HMEEINBN_01651 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
HMEEINBN_01652 1.2e-140 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HMEEINBN_01653 4.7e-224 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HMEEINBN_01654 1.5e-181 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMEEINBN_01655 1.1e-217 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMEEINBN_01656 1.1e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HMEEINBN_01657 5e-207 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HMEEINBN_01658 1.6e-136 yxkH G deacetylase
HMEEINBN_01659 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HMEEINBN_01660 7e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMEEINBN_01661 3.3e-150 rarD S Transporter
HMEEINBN_01662 3.7e-15 T peptidase
HMEEINBN_01663 3e-14 coiA 3.6.4.12 S Competence protein
HMEEINBN_01664 1.3e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HMEEINBN_01665 2.7e-42
HMEEINBN_01666 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMEEINBN_01667 3.3e-43 M1-386
HMEEINBN_01668 2.8e-85
HMEEINBN_01669 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMEEINBN_01670 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
HMEEINBN_01671 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMEEINBN_01672 1.3e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMEEINBN_01673 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMEEINBN_01674 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMEEINBN_01675 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMEEINBN_01676 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMEEINBN_01677 3.5e-217 ftsW D Belongs to the SEDS family
HMEEINBN_01678 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMEEINBN_01679 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMEEINBN_01680 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMEEINBN_01682 2.7e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMEEINBN_01683 1.3e-159 holB 2.7.7.7 L dna polymerase iii
HMEEINBN_01684 1.3e-132 yaaT S stage 0 sporulation protein
HMEEINBN_01685 1.2e-54 yabA L Involved in initiation control of chromosome replication
HMEEINBN_01686 1.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMEEINBN_01687 3.3e-228 amt P Ammonium Transporter
HMEEINBN_01688 8e-52 glnB K Belongs to the P(II) protein family
HMEEINBN_01689 7.8e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
HMEEINBN_01690 1.1e-142 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HMEEINBN_01691 1.8e-82 S Bacterial inner membrane protein
HMEEINBN_01692 8e-114 3.4.17.14, 3.5.1.28 NU amidase activity
HMEEINBN_01693 3.2e-292 nptA P COG1283 Na phosphate symporter
HMEEINBN_01694 1e-212 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMEEINBN_01695 3.3e-220 S membrane
HMEEINBN_01696 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMEEINBN_01697 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMEEINBN_01698 1.7e-38 ynzC S UPF0291 protein
HMEEINBN_01699 6.7e-254 cycA E permease
HMEEINBN_01700 3e-07 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMEEINBN_01701 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMEEINBN_01702 1.2e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMEEINBN_01706 3.4e-69 K Helix-turn-helix
HMEEINBN_01708 4.7e-168 fhuR K transcriptional regulator (lysR family)
HMEEINBN_01709 1.3e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMEEINBN_01710 8.5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMEEINBN_01711 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMEEINBN_01712 1.6e-222 pyrP F uracil Permease
HMEEINBN_01713 6.5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMEEINBN_01714 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HMEEINBN_01715 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HMEEINBN_01716 2.5e-122 2.1.1.223 S Putative SAM-dependent methyltransferase
HMEEINBN_01717 3.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMEEINBN_01718 3.4e-121 macB V ABC transporter, ATP-binding protein
HMEEINBN_01719 1.4e-202 V permease protein
HMEEINBN_01720 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMEEINBN_01721 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMEEINBN_01722 0.0 mdlB V abc transporter atp-binding protein
HMEEINBN_01723 0.0 lmrA V abc transporter atp-binding protein
HMEEINBN_01724 3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMEEINBN_01725 1.4e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMEEINBN_01726 3.8e-211 T signal transduction protein with a C-terminal ATPase domain
HMEEINBN_01727 6.4e-128 rr02 KT response regulator
HMEEINBN_01728 7.1e-164 V ABC transporter
HMEEINBN_01729 1.3e-120 sagI S ABC-2 type transporter
HMEEINBN_01731 2.6e-196 yceA S Belongs to the UPF0176 family
HMEEINBN_01732 1e-27 XK27_00085 K Transcriptional
HMEEINBN_01733 8.9e-20
HMEEINBN_01734 5.9e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
HMEEINBN_01735 3.9e-114 S VIT family
HMEEINBN_01736 4e-139 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMEEINBN_01737 8.8e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HMEEINBN_01738 4.4e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HMEEINBN_01741 3e-142 E Alpha beta hydrolase
HMEEINBN_01742 2.6e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMEEINBN_01743 2.9e-154 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HMEEINBN_01744 9.6e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HMEEINBN_01745 2.3e-171 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HMEEINBN_01746 2.8e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMEEINBN_01747 6.4e-151 V ABC transporter, ATP-binding protein
HMEEINBN_01748 2.9e-51 S ABC-2 family transporter protein
HMEEINBN_01749 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMEEINBN_01750 9.2e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMEEINBN_01751 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HMEEINBN_01752 1.1e-24
HMEEINBN_01753 2.5e-116 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMEEINBN_01754 0.0 U protein secretion
HMEEINBN_01755 1.5e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HMEEINBN_01756 1.2e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HMEEINBN_01757 6.8e-10
HMEEINBN_01758 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMEEINBN_01759 1.1e-142 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMEEINBN_01760 1.6e-199 S Protein of unknown function (DUF3114)
HMEEINBN_01761 4.1e-29 pspC KT PspC domain protein
HMEEINBN_01762 5.2e-119 yqfA K protein, Hemolysin III
HMEEINBN_01763 1.1e-77 K hmm pf08876
HMEEINBN_01764 7.7e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HMEEINBN_01765 1e-210 mvaS 2.3.3.10 I synthase
HMEEINBN_01766 5.5e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMEEINBN_01767 1.1e-89 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMEEINBN_01768 9.7e-22
HMEEINBN_01769 9.8e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMEEINBN_01770 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HMEEINBN_01771 5.2e-240 mmuP E amino acid
HMEEINBN_01772 2.4e-170 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HMEEINBN_01773 2.2e-30 S Domain of unknown function (DUF1912)
HMEEINBN_01774 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
HMEEINBN_01775 2.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMEEINBN_01776 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMEEINBN_01778 1.4e-10
HMEEINBN_01779 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMEEINBN_01780 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
HMEEINBN_01781 4.8e-16 S Protein of unknown function (DUF2969)
HMEEINBN_01784 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
HMEEINBN_01787 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
HMEEINBN_01788 6.4e-117 M Pfam SNARE associated Golgi protein
HMEEINBN_01789 1.6e-227 murN 2.3.2.16 V FemAB family
HMEEINBN_01790 1.4e-173 S oxidoreductase
HMEEINBN_01791 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
HMEEINBN_01792 4.3e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HMEEINBN_01793 0.0 clpE O Belongs to the ClpA ClpB family
HMEEINBN_01794 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMEEINBN_01795 1e-34 ykuJ S protein conserved in bacteria
HMEEINBN_01796 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HMEEINBN_01797 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMEEINBN_01798 4.5e-77 feoA P FeoA domain protein
HMEEINBN_01799 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HMEEINBN_01800 1.7e-08
HMEEINBN_01801 1.5e-149 I Alpha/beta hydrolase family
HMEEINBN_01802 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMEEINBN_01803 8.6e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMEEINBN_01804 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HMEEINBN_01805 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMEEINBN_01806 2.1e-146 licT K antiterminator
HMEEINBN_01807 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMEEINBN_01808 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HMEEINBN_01809 4.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMEEINBN_01810 4.6e-146 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMEEINBN_01811 1.3e-94 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMEEINBN_01812 2.1e-219 mdtG EGP Major facilitator Superfamily
HMEEINBN_01813 2e-33 secG U Preprotein translocase subunit SecG
HMEEINBN_01814 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMEEINBN_01815 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMEEINBN_01816 5.9e-274 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMEEINBN_01817 8.4e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HMEEINBN_01818 5.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HMEEINBN_01819 2.4e-181 ccpA K Catabolite control protein A
HMEEINBN_01820 3.6e-199 yyaQ S YjbR
HMEEINBN_01821 6.4e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMEEINBN_01822 3.3e-77 yueI S Protein of unknown function (DUF1694)
HMEEINBN_01823 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMEEINBN_01824 1.2e-25 WQ51_00785
HMEEINBN_01825 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMEEINBN_01826 1.7e-218 ywbD 2.1.1.191 J Methyltransferase
HMEEINBN_01827 4.1e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMEEINBN_01828 2.6e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMEEINBN_01829 1.7e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMEEINBN_01830 7.1e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMEEINBN_01831 2.3e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HMEEINBN_01832 4.2e-53 yheA S Belongs to the UPF0342 family
HMEEINBN_01833 3.8e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMEEINBN_01834 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMEEINBN_01835 2.2e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMEEINBN_01836 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
HMEEINBN_01837 1.5e-248 msrR K Transcriptional regulator
HMEEINBN_01838 1.5e-148 ydiA P C4-dicarboxylate transporter malic acid transport
HMEEINBN_01839 1.9e-200 I acyl-CoA dehydrogenase
HMEEINBN_01840 2e-97 mip S hydroperoxide reductase activity
HMEEINBN_01841 1e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMEEINBN_01842 7.6e-36 S Pentapeptide repeat protein
HMEEINBN_01843 6.3e-18
HMEEINBN_01844 2e-38 K acetyltransferase
HMEEINBN_01846 4.1e-12
HMEEINBN_01848 1.4e-11 L Resolvase, N terminal domain
HMEEINBN_01849 3e-113 K Psort location Cytoplasmic, score
HMEEINBN_01850 1e-142 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMEEINBN_01851 5.8e-132 S Domain of unknown function (DUF4336)
HMEEINBN_01852 7e-204 yeaN P transporter
HMEEINBN_01853 4.2e-150 yitS S EDD domain protein, DegV family
HMEEINBN_01854 5.2e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
HMEEINBN_01855 5.4e-110 cutC P Participates in the control of copper homeostasis
HMEEINBN_01857 7.1e-21 S Domain of unknown function (DUF4767)
HMEEINBN_01858 1.6e-292 norB P Major facilitator superfamily
HMEEINBN_01859 1.8e-90 tetR K transcriptional regulator
HMEEINBN_01860 9.9e-152 S Domain of unknown function (DUF4300)
HMEEINBN_01861 2.3e-123 V CAAX protease self-immunity
HMEEINBN_01862 2.5e-157 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMEEINBN_01863 7.1e-133 fecE 3.6.3.34 HP ABC transporter
HMEEINBN_01864 1e-171 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HMEEINBN_01865 2.4e-119 ybbA S Putative esterase
HMEEINBN_01866 2.4e-47
HMEEINBN_01867 9.5e-122 V CAAX protease self-immunity
HMEEINBN_01868 6.8e-11
HMEEINBN_01869 2.5e-18 M Bacterial lipoprotein
HMEEINBN_01870 1.5e-57 S Protein of unknown function (DUF1722)
HMEEINBN_01871 8.8e-65 yqeB S Pyrimidine dimer DNA glycosylase
HMEEINBN_01873 3.6e-50
HMEEINBN_01874 7.5e-93 S CAAX protease self-immunity
HMEEINBN_01875 1.3e-47 estA E GDSL-like Lipase/Acylhydrolase
HMEEINBN_01876 3.5e-42 estA E GDSL-like Lipase/Acylhydrolase
HMEEINBN_01877 3.8e-100
HMEEINBN_01878 1.3e-285 sulP P Sulfate permease and related transporters (MFS superfamily)
HMEEINBN_01879 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMEEINBN_01880 1.9e-169 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMEEINBN_01881 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMEEINBN_01882 1.3e-169 S CRISPR-associated protein Csn2 subfamily St
HMEEINBN_01885 1.9e-07
HMEEINBN_01890 4.2e-198 L Belongs to the 'phage' integrase family
HMEEINBN_01891 3.5e-28 S Domain of unknown function (DUF3173)
HMEEINBN_01892 3.4e-67
HMEEINBN_01893 7e-228 L Replication initiation factor
HMEEINBN_01894 7.2e-75
HMEEINBN_01895 1e-75 K Transcriptional
HMEEINBN_01896 3.6e-49 qacC P COG2076 Membrane transporters of cations and cationic drugs
HMEEINBN_01897 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMEEINBN_01898 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HMEEINBN_01899 1.2e-35 XK27_02060 S Transglycosylase associated protein
HMEEINBN_01900 3.9e-72 badR K Transcriptional regulator, marr family
HMEEINBN_01901 3.2e-95 S reductase
HMEEINBN_01903 3.3e-286 ahpF O alkyl hydroperoxide reductase
HMEEINBN_01904 3.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
HMEEINBN_01905 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
HMEEINBN_01906 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMEEINBN_01907 1.6e-82 S Putative small multi-drug export protein
HMEEINBN_01908 1.8e-75 ctsR K Belongs to the CtsR family
HMEEINBN_01909 0.0 clpC O Belongs to the ClpA ClpB family
HMEEINBN_01910 3.5e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMEEINBN_01911 2.8e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMEEINBN_01912 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HMEEINBN_01913 2.3e-139 S SseB protein N-terminal domain
HMEEINBN_01914 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
HMEEINBN_01916 6.9e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMEEINBN_01917 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMEEINBN_01919 1.4e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMEEINBN_01920 6e-91 yacP S RNA-binding protein containing a PIN domain
HMEEINBN_01921 7.7e-152 degV S DegV family
HMEEINBN_01923 5.1e-22 K Transcriptional
HMEEINBN_01924 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMEEINBN_01925 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HMEEINBN_01927 1.2e-101 cadD P cadmium resistance
HMEEINBN_01928 4.5e-55 cadC K Bacterial regulatory protein, arsR family
HMEEINBN_01929 1.8e-19
HMEEINBN_01930 4.5e-29 K Helix-turn-helix domain
HMEEINBN_01932 2e-149 srtB 3.4.22.70 S Sortase family
HMEEINBN_01933 1.5e-233 capA M Bacterial capsule synthesis protein
HMEEINBN_01934 1e-38 gcvR T UPF0237 protein
HMEEINBN_01935 3.9e-243 XK27_08635 S UPF0210 protein
HMEEINBN_01936 2.3e-130 ais G Phosphoglycerate mutase
HMEEINBN_01937 5.3e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HMEEINBN_01938 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
HMEEINBN_01939 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMEEINBN_01940 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMEEINBN_01941 2.3e-302 dnaK O Heat shock 70 kDa protein
HMEEINBN_01942 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMEEINBN_01943 1e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMEEINBN_01944 3.1e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HMEEINBN_01945 7.4e-80 hmpT S cog cog4720

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)