ORF_ID e_value Gene_name EC_number CAZy COGs Description
KAKIOLKG_00001 3.4e-135 fecE 3.6.3.34 HP ABC transporter
KAKIOLKG_00002 2.5e-157 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KAKIOLKG_00003 1.9e-114 V CAAX protease self-immunity
KAKIOLKG_00004 9.9e-152 S Domain of unknown function (DUF4300)
KAKIOLKG_00005 1.6e-20 S Domain of unknown function (DUF4767)
KAKIOLKG_00007 3.9e-108 cutC P Participates in the control of copper homeostasis
KAKIOLKG_00008 8.1e-130 S CAAX amino terminal protease family
KAKIOLKG_00009 2.5e-98 ypgQ F HD superfamily hydrolase
KAKIOLKG_00010 5.2e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
KAKIOLKG_00011 8.4e-151 yitS S EDD domain protein, DegV family
KAKIOLKG_00012 6.3e-205 yeaN P transporter
KAKIOLKG_00013 3.7e-73 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
KAKIOLKG_00014 1.6e-85 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KAKIOLKG_00015 1.7e-134 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KAKIOLKG_00016 6.8e-99 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KAKIOLKG_00017 0.0 S dextransucrase activity
KAKIOLKG_00018 0.0 M Putative cell wall binding repeat
KAKIOLKG_00019 0.0 S dextransucrase activity
KAKIOLKG_00020 1.2e-21 S dextransucrase activity
KAKIOLKG_00021 1.1e-95 malF P ABC transporter (Permease
KAKIOLKG_00022 2.2e-151 malG P ABC transporter (Permease
KAKIOLKG_00023 4.7e-213 msmX P Belongs to the ABC transporter superfamily
KAKIOLKG_00024 3e-24 tatA U protein secretion
KAKIOLKG_00025 3.6e-115 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KAKIOLKG_00026 8e-286 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KAKIOLKG_00027 4e-231 ycdB P peroxidase
KAKIOLKG_00028 5.4e-145 ycdO P periplasmic lipoprotein involved in iron transport
KAKIOLKG_00029 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KAKIOLKG_00030 1e-108 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KAKIOLKG_00031 3.1e-92 adk 2.7.4.3 F topology modulation protein
KAKIOLKG_00032 6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KAKIOLKG_00033 2.6e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KAKIOLKG_00034 2.8e-35 XK27_09805 S MORN repeat protein
KAKIOLKG_00035 0.0 XK27_09800 I Acyltransferase
KAKIOLKG_00036 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KAKIOLKG_00037 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KAKIOLKG_00038 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KAKIOLKG_00039 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
KAKIOLKG_00040 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KAKIOLKG_00041 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KAKIOLKG_00042 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KAKIOLKG_00043 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KAKIOLKG_00044 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KAKIOLKG_00045 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KAKIOLKG_00046 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KAKIOLKG_00047 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KAKIOLKG_00049 1.9e-07
KAKIOLKG_00054 4.1e-201 L Belongs to the 'phage' integrase family
KAKIOLKG_00055 3.5e-28 S Domain of unknown function (DUF3173)
KAKIOLKG_00056 2.6e-67
KAKIOLKG_00057 2.5e-225 L Replication initiation factor
KAKIOLKG_00058 3.6e-74
KAKIOLKG_00059 2.8e-76 K transcriptional
KAKIOLKG_00061 8.4e-148
KAKIOLKG_00063 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KAKIOLKG_00064 6.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KAKIOLKG_00065 1.2e-35 XK27_02060 S Transglycosylase associated protein
KAKIOLKG_00066 6.3e-70 badR K Transcriptional regulator, marr family
KAKIOLKG_00067 3.3e-92 S reductase
KAKIOLKG_00069 8.6e-287 ahpF O alkyl hydroperoxide reductase
KAKIOLKG_00070 4.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
KAKIOLKG_00071 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
KAKIOLKG_00072 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KAKIOLKG_00073 1.6e-82 S Putative small multi-drug export protein
KAKIOLKG_00074 1.8e-75 ctsR K Belongs to the CtsR family
KAKIOLKG_00075 0.0 clpC O Belongs to the ClpA ClpB family
KAKIOLKG_00076 9.3e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KAKIOLKG_00077 3.6e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KAKIOLKG_00078 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KAKIOLKG_00079 4.7e-140 S SseB protein N-terminal domain
KAKIOLKG_00080 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
KAKIOLKG_00081 2.4e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KAKIOLKG_00082 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KAKIOLKG_00084 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAKIOLKG_00085 6e-91 yacP S RNA-binding protein containing a PIN domain
KAKIOLKG_00086 1.7e-143 degV S DegV family
KAKIOLKG_00088 5.1e-22 K Transcriptional
KAKIOLKG_00089 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KAKIOLKG_00090 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KAKIOLKG_00091 2.1e-195 int L Belongs to the 'phage' integrase family
KAKIOLKG_00092 1.2e-42 S Helix-turn-helix domain
KAKIOLKG_00094 3.9e-172 isp2 S pathogenesis
KAKIOLKG_00095 2.8e-29
KAKIOLKG_00096 7.4e-256
KAKIOLKG_00097 0.0 yddE S AAA-like domain
KAKIOLKG_00098 2.7e-70 S TcpE family
KAKIOLKG_00099 3.2e-33
KAKIOLKG_00100 1.2e-159 S Conjugative transposon protein TcpC
KAKIOLKG_00101 3e-88
KAKIOLKG_00102 4.3e-33
KAKIOLKG_00103 2.3e-226 K Replication initiation factor
KAKIOLKG_00104 2.4e-217 L Belongs to the 'phage' integrase family
KAKIOLKG_00105 4.5e-10 S Domain of unknown function (DUF3173)
KAKIOLKG_00106 3.2e-88 L Replication initiation factor
KAKIOLKG_00108 2.9e-13 K Transcriptional
KAKIOLKG_00109 1.1e-11
KAKIOLKG_00110 3.6e-161
KAKIOLKG_00111 8e-278 ydcQ D Ftsk spoiiie family protein
KAKIOLKG_00112 2.7e-74
KAKIOLKG_00113 1.3e-42
KAKIOLKG_00114 8.6e-46 K Helix-turn-helix XRE-family like proteins
KAKIOLKG_00115 7.9e-113 prrC S AAA domain
KAKIOLKG_00116 5.4e-129 E IrrE N-terminal-like domain
KAKIOLKG_00117 6.6e-109 K Peptidase S24-like
KAKIOLKG_00118 2.7e-21
KAKIOLKG_00119 1.6e-74 LV Eco57I restriction-modification methylase
KAKIOLKG_00120 2.6e-130 V DNA modification
KAKIOLKG_00121 2.5e-122 V AAA domain (dynein-related subfamily)
KAKIOLKG_00122 2.4e-96 V COG4268 McrBC 5-methylcytosine restriction system component
KAKIOLKG_00124 4.3e-50 S AAA domain, putative AbiEii toxin, Type IV TA system
KAKIOLKG_00125 4.1e-27 V HNH endonuclease
KAKIOLKG_00126 1.2e-18
KAKIOLKG_00127 1.5e-29 K Helix-turn-helix domain
KAKIOLKG_00129 2e-149 srtB 3.4.22.70 S Sortase family
KAKIOLKG_00130 5.7e-233 capA M Bacterial capsule synthesis protein
KAKIOLKG_00131 1e-38 gcvR T UPF0237 protein
KAKIOLKG_00132 5.1e-243 XK27_08635 S UPF0210 protein
KAKIOLKG_00133 1.1e-130 ais G Phosphoglycerate mutase
KAKIOLKG_00134 4.1e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KAKIOLKG_00135 7.9e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
KAKIOLKG_00136 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KAKIOLKG_00137 4.1e-63 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KAKIOLKG_00138 1.9e-301 dnaK O Heat shock 70 kDa protein
KAKIOLKG_00139 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KAKIOLKG_00140 2.2e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KAKIOLKG_00141 3.9e-131 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KAKIOLKG_00142 2.2e-79 hmpT S cog cog4720
KAKIOLKG_00143 1.1e-294 yfmM S abc transporter atp-binding protein
KAKIOLKG_00144 3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
KAKIOLKG_00145 1.3e-151 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KAKIOLKG_00146 8.2e-85 S ECF-type riboflavin transporter, S component
KAKIOLKG_00148 5.1e-237 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KAKIOLKG_00149 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KAKIOLKG_00151 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KAKIOLKG_00152 2.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KAKIOLKG_00153 3.9e-65 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KAKIOLKG_00154 2.6e-61 XK27_02070 S nitroreductase
KAKIOLKG_00155 1.1e-20
KAKIOLKG_00156 2.5e-27 XK27_07105 K transcriptional
KAKIOLKG_00157 1.1e-06 S Protein of unknown function (DUF3169)
KAKIOLKG_00158 5.7e-169 ydhF S Aldo keto reductase
KAKIOLKG_00159 4.8e-97 K WHG domain
KAKIOLKG_00160 1.3e-122 V abc transporter atp-binding protein
KAKIOLKG_00161 3.4e-203 P FtsX-like permease family
KAKIOLKG_00162 1.5e-42 S Sugar efflux transporter for intercellular exchange
KAKIOLKG_00163 8.6e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KAKIOLKG_00164 1.2e-175 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
KAKIOLKG_00165 1.8e-164 ET ABC transporter substrate-binding protein
KAKIOLKG_00166 2.5e-108 ytmL P ABC transporter (Permease
KAKIOLKG_00167 1.4e-59 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAKIOLKG_00168 6.6e-119 alkD L Dna alkylation repair
KAKIOLKG_00169 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KAKIOLKG_00170 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KAKIOLKG_00171 7.1e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KAKIOLKG_00172 0.0 smc D Required for chromosome condensation and partitioning
KAKIOLKG_00173 1.2e-89 S Protein of unknown function (DUF3278)
KAKIOLKG_00174 1.8e-22 WQ51_00220 K Helix-turn-helix domain
KAKIOLKG_00175 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
KAKIOLKG_00176 1.8e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
KAKIOLKG_00177 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
KAKIOLKG_00178 3e-152 XK27_05675 S Esterase
KAKIOLKG_00179 2.3e-161 XK27_05670 S Putative esterase
KAKIOLKG_00180 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KAKIOLKG_00181 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KAKIOLKG_00182 3e-38 ptsH G phosphocarrier protein Hpr
KAKIOLKG_00183 2.1e-16 Q Methyltransferase domain protein
KAKIOLKG_00184 4.8e-45 L transposase activity
KAKIOLKG_00185 2.3e-93 L Molecular Function DNA binding, Biological Process DNA recombination
KAKIOLKG_00186 1.3e-105 K Transcriptional regulator
KAKIOLKG_00187 8.1e-131 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
KAKIOLKG_00188 5.2e-255 6.1.1.6 S Psort location CytoplasmicMembrane, score
KAKIOLKG_00189 5.4e-33 S Protein of unknown function (DUF1648)
KAKIOLKG_00190 6e-55 K Transcriptional regulator
KAKIOLKG_00191 4e-128 S CAAX amino terminal protease family protein
KAKIOLKG_00192 2e-97 J Acetyltransferase (GNAT) domain
KAKIOLKG_00193 2.6e-95
KAKIOLKG_00194 5.3e-44
KAKIOLKG_00195 1.1e-56 S ParE toxin of type II toxin-antitoxin system, parDE
KAKIOLKG_00196 1.1e-147 cbiO2 P ABC transporter, ATP-binding protein
KAKIOLKG_00197 1e-156 P abc transporter atp-binding protein
KAKIOLKG_00198 2.8e-132 cbiQ P cobalt transport
KAKIOLKG_00199 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
KAKIOLKG_00200 1.8e-142 S Phenazine biosynthesis protein
KAKIOLKG_00201 1.2e-89 tetR K transcriptional regulator
KAKIOLKG_00202 1.5e-124 V abc transporter atp-binding protein
KAKIOLKG_00203 0.0 V ABC transporter (Permease
KAKIOLKG_00204 1.4e-184 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KAKIOLKG_00205 6.6e-08
KAKIOLKG_00206 8.5e-150 I Alpha/beta hydrolase family
KAKIOLKG_00207 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KAKIOLKG_00208 4.3e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KAKIOLKG_00209 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KAKIOLKG_00210 2.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KAKIOLKG_00211 2.1e-149 licT K antiterminator
KAKIOLKG_00212 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KAKIOLKG_00213 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KAKIOLKG_00214 2.2e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KAKIOLKG_00215 6.9e-150 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KAKIOLKG_00216 2e-101 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KAKIOLKG_00217 1.4e-84 mdtG EGP Major facilitator Superfamily
KAKIOLKG_00218 1.1e-124 mdtG EGP Major facilitator Superfamily
KAKIOLKG_00219 2e-33 secG U Preprotein translocase subunit SecG
KAKIOLKG_00220 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KAKIOLKG_00221 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KAKIOLKG_00222 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAKIOLKG_00223 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KAKIOLKG_00224 2.1e-194 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KAKIOLKG_00225 2.4e-181 ccpA K Catabolite control protein A
KAKIOLKG_00226 8e-199 yyaQ S YjbR
KAKIOLKG_00227 5.2e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KAKIOLKG_00228 7.4e-77 yueI S Protein of unknown function (DUF1694)
KAKIOLKG_00229 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KAKIOLKG_00230 6.7e-207 S Phage integrase family
KAKIOLKG_00231 1.3e-18 E Zn peptidase
KAKIOLKG_00232 7.3e-89 V Abi-like protein
KAKIOLKG_00233 5.6e-51 S protein disulfide oxidoreductase activity
KAKIOLKG_00234 1.6e-07 K sequence-specific DNA binding
KAKIOLKG_00235 9.1e-08
KAKIOLKG_00236 3.4e-09
KAKIOLKG_00237 2e-25
KAKIOLKG_00239 3e-76 M Pilin isopeptide linkage domain protein
KAKIOLKG_00240 1.5e-178 D AAA domain
KAKIOLKG_00241 1.2e-128 S AAA domain
KAKIOLKG_00242 4.2e-50
KAKIOLKG_00243 5.3e-77
KAKIOLKG_00244 2.1e-68
KAKIOLKG_00245 2.1e-267 L helicase
KAKIOLKG_00246 0.0 L Primase C terminal 2 (PriCT-2)
KAKIOLKG_00247 1.5e-15
KAKIOLKG_00248 3.9e-58 rusA L crossover junction endodeoxyribonuclease RusA
KAKIOLKG_00249 1.4e-07
KAKIOLKG_00252 1e-26 S Protein of unknown function (DUF1642)
KAKIOLKG_00255 1.2e-45 S sequence-specific DNA binding
KAKIOLKG_00258 8e-62 S Protein of unknown function (DUF1492)
KAKIOLKG_00259 4.8e-72 yqaS L DNA packaging
KAKIOLKG_00260 9.3e-226 L Phage terminase, large subunit
KAKIOLKG_00261 2e-253 S Phage portal protein, SPP1 Gp6-like
KAKIOLKG_00262 4.9e-184 S Phage minor capsid protein 2
KAKIOLKG_00263 1.3e-71 S Phage minor structural protein GP20
KAKIOLKG_00264 2.3e-140 S peptidase activity
KAKIOLKG_00266 1.1e-57
KAKIOLKG_00267 2.1e-28 S Minor capsid protein
KAKIOLKG_00268 4.4e-48 S Minor capsid protein
KAKIOLKG_00269 1.4e-66 S Minor capsid protein from bacteriophage
KAKIOLKG_00270 1.8e-72
KAKIOLKG_00271 5.2e-25
KAKIOLKG_00272 2e-85 S Bacteriophage Gp15 protein
KAKIOLKG_00273 3.9e-234 S transmembrane transport
KAKIOLKG_00274 9.9e-108
KAKIOLKG_00275 2.5e-168 S peptidoglycan catabolic process
KAKIOLKG_00276 5e-21
KAKIOLKG_00277 1.4e-45
KAKIOLKG_00278 2.4e-28 hol S Holin, phage phi LC3 family
KAKIOLKG_00279 4.5e-132 S peptidoglycan catabolic process
KAKIOLKG_00280 1.2e-25 WQ51_00785
KAKIOLKG_00281 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KAKIOLKG_00282 2.7e-216 ywbD 2.1.1.191 J Methyltransferase
KAKIOLKG_00283 3.2e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KAKIOLKG_00284 1.3e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KAKIOLKG_00285 3.8e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KAKIOLKG_00286 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KAKIOLKG_00287 5.9e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KAKIOLKG_00288 4.2e-53 yheA S Belongs to the UPF0342 family
KAKIOLKG_00289 2.5e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KAKIOLKG_00290 9.2e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KAKIOLKG_00291 1e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KAKIOLKG_00292 3.9e-153 pheA 4.2.1.51 E Prephenate dehydratase
KAKIOLKG_00293 3.1e-238 msrR K Transcriptional regulator
KAKIOLKG_00294 1.2e-145 ydiA P C4-dicarboxylate transporter malic acid transport protein
KAKIOLKG_00295 2.5e-200 I acyl-CoA dehydrogenase
KAKIOLKG_00296 2.7e-97 mip S hydroperoxide reductase activity
KAKIOLKG_00297 3.6e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAKIOLKG_00298 3.7e-66 silP 1.9.3.1, 3.6.3.54 S cog cog4633
KAKIOLKG_00299 2.5e-65 copY K Copper transport repressor, CopY TcrY family
KAKIOLKG_00300 5e-152 L PFAM Integrase catalytic region
KAKIOLKG_00301 7.6e-186 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
KAKIOLKG_00302 2.7e-194 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KAKIOLKG_00303 1.7e-157 czcD P cation diffusion facilitator family transporter
KAKIOLKG_00304 4.9e-96 K Transcriptional regulator, TetR family
KAKIOLKG_00305 1.7e-68 S Protein of unknown function with HXXEE motif
KAKIOLKG_00306 7e-11
KAKIOLKG_00307 2.5e-11 V Glucan-binding protein C
KAKIOLKG_00308 1.6e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
KAKIOLKG_00309 1.4e-272 pepV 3.5.1.18 E Dipeptidase
KAKIOLKG_00310 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KAKIOLKG_00311 1e-90 yybC
KAKIOLKG_00312 4.2e-83 XK27_03610 K Gnat family
KAKIOLKG_00313 8e-288 lpdA 1.8.1.4 C Dehydrogenase
KAKIOLKG_00314 0.0 3.5.1.28 NU amidase activity
KAKIOLKG_00315 6.7e-119 sdaAB 4.3.1.17 E L-serine dehydratase
KAKIOLKG_00316 1.3e-146 sdaAA 4.3.1.17 E L-serine dehydratase
KAKIOLKG_00317 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
KAKIOLKG_00318 3.7e-72 yjlA EG membrane
KAKIOLKG_00319 0.0 M domain protein
KAKIOLKG_00321 3.6e-263 3.5.1.28 NU GBS Bsp-like repeat
KAKIOLKG_00322 2.8e-37 L COG3547 Transposase and inactivated derivatives
KAKIOLKG_00323 9e-108 L COG3547 Transposase and inactivated derivatives
KAKIOLKG_00324 8.5e-40 L Integrase core domain
KAKIOLKG_00325 5.9e-225 thrE K Psort location CytoplasmicMembrane, score
KAKIOLKG_00326 2.4e-34 S Immunity protein 41
KAKIOLKG_00327 0.0 pepO 3.4.24.71 O Peptidase family M13
KAKIOLKG_00328 9e-08 S Enterocin A Immunity
KAKIOLKG_00329 7.7e-68 S Asp23 family, cell envelope-related function
KAKIOLKG_00330 1.5e-22 S Small integral membrane protein
KAKIOLKG_00331 4.7e-97
KAKIOLKG_00332 5.5e-31 S Membrane
KAKIOLKG_00333 5.2e-171 S Domain of unknown function (DUF389)
KAKIOLKG_00334 1.3e-157 yegS 2.7.1.107 I Diacylglycerol kinase
KAKIOLKG_00335 3.4e-126 ybbA S Putative esterase
KAKIOLKG_00336 6.8e-84 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KAKIOLKG_00337 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KAKIOLKG_00338 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KAKIOLKG_00339 3e-84 yxjI S LURP-one-related
KAKIOLKG_00340 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KAKIOLKG_00341 3e-119 yrrM 2.1.1.104 S O-Methyltransferase
KAKIOLKG_00342 3.5e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
KAKIOLKG_00343 0.0 pepF E oligoendopeptidase F
KAKIOLKG_00344 3.3e-175 coiA 3.6.4.12 S Competence protein
KAKIOLKG_00345 1.2e-274 S Glucan-binding protein C
KAKIOLKG_00346 2e-108 S CAAX amino terminal protease family protein
KAKIOLKG_00347 4.7e-168 K transcriptional regulator (lysR family)
KAKIOLKG_00348 9e-161 S reductase
KAKIOLKG_00349 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KAKIOLKG_00353 1.2e-186 phoH T phosphate starvation-inducible protein PhoH
KAKIOLKG_00354 7.2e-130 sip M LysM domain protein
KAKIOLKG_00355 3.7e-34 yozE S Belongs to the UPF0346 family
KAKIOLKG_00356 5.9e-160 cvfB S Protein conserved in bacteria
KAKIOLKG_00357 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KAKIOLKG_00358 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KAKIOLKG_00359 1.1e-212 sptS 2.7.13.3 T Histidine kinase
KAKIOLKG_00360 4.6e-115 T response regulator
KAKIOLKG_00361 1.4e-110 2.7.6.5 S Region found in RelA / SpoT proteins
KAKIOLKG_00362 5.7e-112 K Acetyltransferase (GNAT) family
KAKIOLKG_00363 0.0 lmrA2 V abc transporter atp-binding protein
KAKIOLKG_00364 2.5e-309 lmrA1 V abc transporter atp-binding protein
KAKIOLKG_00365 2.8e-73 K DNA-binding transcription factor activity
KAKIOLKG_00366 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KAKIOLKG_00367 1.7e-277 S Psort location CytoplasmicMembrane, score
KAKIOLKG_00368 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KAKIOLKG_00369 8e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KAKIOLKG_00370 3.7e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KAKIOLKG_00371 1.7e-26 U response to pH
KAKIOLKG_00372 0.0 yfmR S abc transporter atp-binding protein
KAKIOLKG_00373 7.3e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KAKIOLKG_00374 3.9e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KAKIOLKG_00375 1.1e-147 XK27_08360 S EDD domain protein, DegV family
KAKIOLKG_00376 5e-63 WQ51_03320 S cog cog4835
KAKIOLKG_00377 7.2e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KAKIOLKG_00378 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KAKIOLKG_00379 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KAKIOLKG_00380 9.6e-92 2.3.1.128 K acetyltransferase
KAKIOLKG_00381 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KAKIOLKG_00382 7.9e-293 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KAKIOLKG_00383 7.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KAKIOLKG_00384 3.7e-210 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KAKIOLKG_00386 3e-229 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KAKIOLKG_00387 2.1e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAKIOLKG_00388 0.0 fruA 2.7.1.202 G phosphotransferase system
KAKIOLKG_00389 1.3e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KAKIOLKG_00390 4e-112 fruR K transcriptional
KAKIOLKG_00391 4.5e-52 V ABC-2 family transporter protein
KAKIOLKG_00392 1.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
KAKIOLKG_00393 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KAKIOLKG_00394 1.3e-156 dprA LU DNA protecting protein DprA
KAKIOLKG_00395 5.7e-141 GK ROK family
KAKIOLKG_00397 5.5e-112 D CobQ CobB MinD ParA nucleotide binding domain protein
KAKIOLKG_00399 1.7e-126 S Uncharacterised protein family (UPF0236)
KAKIOLKG_00400 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAKIOLKG_00401 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAKIOLKG_00402 1e-68 S cog cog4699
KAKIOLKG_00403 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAKIOLKG_00404 1.5e-147 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KAKIOLKG_00405 2.2e-43 comGC U Required for transformation and DNA binding
KAKIOLKG_00406 4.2e-69 cglD NU Competence protein
KAKIOLKG_00407 3.1e-15 NU Type II secretory pathway pseudopilin
KAKIOLKG_00408 2.6e-71 comGF U Competence protein ComGF
KAKIOLKG_00409 2e-12 comGF U Putative Competence protein ComGF
KAKIOLKG_00410 3.8e-176 ytxK 2.1.1.72 L DNA methylase
KAKIOLKG_00411 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KAKIOLKG_00412 8.8e-27 lanR K sequence-specific DNA binding
KAKIOLKG_00413 7.3e-110 V CAAX protease self-immunity
KAKIOLKG_00415 9.6e-102 S CAAX amino terminal protease family protein
KAKIOLKG_00416 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KAKIOLKG_00417 9.1e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KAKIOLKG_00418 5.9e-08 XK27_10305 S Domain of unknown function (DUF4651)
KAKIOLKG_00419 7.9e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KAKIOLKG_00420 4.4e-09 S NTF2 fold immunity protein
KAKIOLKG_00421 3.3e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KAKIOLKG_00422 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KAKIOLKG_00423 7.3e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KAKIOLKG_00427 4.6e-157 rrmA 2.1.1.187 Q methyltransferase
KAKIOLKG_00428 4e-136 S HAD hydrolase, family IA, variant
KAKIOLKG_00429 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KAKIOLKG_00430 8.7e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KAKIOLKG_00431 2.2e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KAKIOLKG_00432 4.4e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KAKIOLKG_00433 1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KAKIOLKG_00434 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KAKIOLKG_00435 8.5e-91 XK27_08585 S Psort location CytoplasmicMembrane, score
KAKIOLKG_00436 5.3e-139 fnt P Formate nitrite transporter
KAKIOLKG_00437 7.9e-230 XK27_09615 C reductase
KAKIOLKG_00438 8.2e-108 XK27_09620 S FMN reductase (NADPH) activity
KAKIOLKG_00439 1.3e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KAKIOLKG_00440 2.3e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
KAKIOLKG_00441 3.4e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KAKIOLKG_00442 3.1e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
KAKIOLKG_00443 7.3e-86 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KAKIOLKG_00444 1.2e-50 S Protein of unknown function (DUF3397)
KAKIOLKG_00445 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KAKIOLKG_00446 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KAKIOLKG_00447 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KAKIOLKG_00448 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KAKIOLKG_00449 6.3e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KAKIOLKG_00450 3e-151 hpk9 2.7.13.3 T protein histidine kinase activity
KAKIOLKG_00451 9.6e-207 hpk9 2.7.13.3 T protein histidine kinase activity
KAKIOLKG_00452 2.3e-224 fasC 2.7.13.3 T protein histidine kinase activity
KAKIOLKG_00453 7.2e-130 fasA KT Response regulator of the LytR AlgR family
KAKIOLKG_00454 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KAKIOLKG_00455 1.6e-263 argH 4.3.2.1 E Argininosuccinate lyase
KAKIOLKG_00456 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KAKIOLKG_00457 1.3e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KAKIOLKG_00458 7.4e-173 jag S RNA-binding protein
KAKIOLKG_00459 2.7e-103 K Transcriptional regulator
KAKIOLKG_00460 5.3e-101 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
KAKIOLKG_00461 3.4e-14 rpmH J Ribosomal protein L34
KAKIOLKG_00462 3.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KAKIOLKG_00463 4.6e-36 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KAKIOLKG_00464 9.7e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KAKIOLKG_00465 1.5e-86 ebsA S Family of unknown function (DUF5322)
KAKIOLKG_00466 2.5e-17 M LysM domain
KAKIOLKG_00467 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KAKIOLKG_00468 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KAKIOLKG_00469 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KAKIOLKG_00470 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KAKIOLKG_00471 2.2e-174 O protein import
KAKIOLKG_00472 3.9e-167 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KAKIOLKG_00473 2.9e-17 yjdB S Domain of unknown function (DUF4767)
KAKIOLKG_00474 1.3e-198 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KAKIOLKG_00476 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
KAKIOLKG_00477 3.4e-72 S QueT transporter
KAKIOLKG_00479 2e-172 yfjR K regulation of single-species biofilm formation
KAKIOLKG_00481 7.4e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KAKIOLKG_00482 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KAKIOLKG_00483 1.7e-85 ccl S cog cog4708
KAKIOLKG_00484 2.8e-163 rbn E Belongs to the UPF0761 family
KAKIOLKG_00485 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KAKIOLKG_00486 3e-232 ytoI K transcriptional regulator containing CBS domains
KAKIOLKG_00487 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KAKIOLKG_00488 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAKIOLKG_00489 0.0 comEC S Competence protein ComEC
KAKIOLKG_00490 2.4e-95 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KAKIOLKG_00491 2.2e-142 plsC 2.3.1.51 I Acyltransferase
KAKIOLKG_00492 2.2e-144 nodB3 G Polysaccharide deacetylase
KAKIOLKG_00493 6e-140 yabB 2.1.1.223 L Methyltransferase
KAKIOLKG_00494 6.6e-41 yazA L endonuclease containing a URI domain
KAKIOLKG_00495 1.1e-27 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
KAKIOLKG_00496 2.2e-253 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KAKIOLKG_00497 1.8e-151 corA P CorA-like protein
KAKIOLKG_00498 9.6e-62 yjqA S Bacterial PH domain
KAKIOLKG_00499 6.9e-96 thiT S Thiamine transporter
KAKIOLKG_00500 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KAKIOLKG_00501 1.3e-117 ywaF S Integral membrane protein (intg_mem_TP0381)
KAKIOLKG_00502 1.5e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KAKIOLKG_00506 3.3e-155 cjaA ET ABC transporter substrate-binding protein
KAKIOLKG_00507 1.5e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
KAKIOLKG_00508 3e-106 P ABC transporter (Permease
KAKIOLKG_00509 3e-114 papP P ABC transporter (Permease
KAKIOLKG_00510 3.5e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KAKIOLKG_00511 1.4e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
KAKIOLKG_00512 0.0 copA 3.6.3.54 P P-type ATPase
KAKIOLKG_00513 1.8e-72 copY K negative regulation of transcription, DNA-templated
KAKIOLKG_00514 3.5e-179 EGP Major facilitator Superfamily
KAKIOLKG_00518 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KAKIOLKG_00519 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KAKIOLKG_00520 3.9e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KAKIOLKG_00521 5.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KAKIOLKG_00522 2.3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KAKIOLKG_00523 2.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KAKIOLKG_00524 6.5e-215 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KAKIOLKG_00525 6.7e-11 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KAKIOLKG_00526 2.6e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
KAKIOLKG_00527 2.9e-58
KAKIOLKG_00528 0.0 ctpE P E1-E2 ATPase
KAKIOLKG_00529 1.2e-196 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
KAKIOLKG_00530 1.8e-279 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
KAKIOLKG_00531 4.3e-141 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KAKIOLKG_00532 8e-224 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KAKIOLKG_00533 5.2e-187 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KAKIOLKG_00534 7.8e-219 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KAKIOLKG_00535 2.8e-126 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KAKIOLKG_00536 1.9e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KAKIOLKG_00537 1.6e-128 yxkH G deacetylase
KAKIOLKG_00538 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KAKIOLKG_00539 9.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KAKIOLKG_00540 1.1e-148 rarD S Transporter
KAKIOLKG_00541 2.9e-15 T peptidase
KAKIOLKG_00542 3e-14 coiA 3.6.4.12 S Competence protein
KAKIOLKG_00544 5.5e-101 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KAKIOLKG_00545 2.1e-97 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KAKIOLKG_00546 7.4e-19
KAKIOLKG_00548 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KAKIOLKG_00549 1.2e-182 femA 2.3.2.10, 2.3.2.16 V FemAB family
KAKIOLKG_00550 4.9e-17 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAKIOLKG_00551 2.8e-123 atpB C it plays a direct role in the translocation of protons across the membrane
KAKIOLKG_00552 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KAKIOLKG_00553 3e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KAKIOLKG_00554 2.2e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KAKIOLKG_00555 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KAKIOLKG_00556 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KAKIOLKG_00557 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KAKIOLKG_00558 3e-216 ftsW D Belongs to the SEDS family
KAKIOLKG_00559 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KAKIOLKG_00560 5.8e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KAKIOLKG_00561 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KAKIOLKG_00563 2.7e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KAKIOLKG_00564 1.1e-158 holB 2.7.7.7 L dna polymerase iii
KAKIOLKG_00565 4.9e-132 yaaT S stage 0 sporulation protein
KAKIOLKG_00566 1.2e-54 yabA L Involved in initiation control of chromosome replication
KAKIOLKG_00567 7.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KAKIOLKG_00568 1.3e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
KAKIOLKG_00569 7.9e-100 S HD domain
KAKIOLKG_00570 3.1e-142 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KAKIOLKG_00571 1.7e-74 S Bacterial inner membrane protein
KAKIOLKG_00572 8.8e-113 3.4.17.14, 3.5.1.28 NU amidase activity
KAKIOLKG_00573 3.5e-294 nptA P COG1283 Na phosphate symporter
KAKIOLKG_00574 1.1e-214 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KAKIOLKG_00575 2.3e-46 S membrane
KAKIOLKG_00576 1.9e-67 S Glutathione-dependent formaldehyde-activating
KAKIOLKG_00577 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KAKIOLKG_00578 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KAKIOLKG_00579 3.5e-39 ynzC S UPF0291 protein
KAKIOLKG_00580 3.9e-254 cycA E permease
KAKIOLKG_00581 1.2e-08 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAKIOLKG_00582 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KAKIOLKG_00583 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KAKIOLKG_00585 4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KAKIOLKG_00586 5.2e-87 pat 2.3.1.183 M acetyltransferase
KAKIOLKG_00588 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KAKIOLKG_00589 1.6e-61 smtB K Transcriptional regulator
KAKIOLKG_00590 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
KAKIOLKG_00591 2.4e-75 P Mediates zinc uptake. May also transport other divalent cations
KAKIOLKG_00592 0.0 Q the current gene model (or a revised gene model) may contain a frame shift
KAKIOLKG_00593 1.7e-18 S Domain of unknown function (DUF4649)
KAKIOLKG_00595 5.9e-132 agrA KT Response regulator of the LytR AlgR family
KAKIOLKG_00596 3.5e-228 2.7.13.3 T GHKL domain
KAKIOLKG_00597 2.4e-09 sraP UW domain, Protein
KAKIOLKG_00599 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KAKIOLKG_00600 6.6e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KAKIOLKG_00601 5.5e-207 hpk9 2.7.13.3 T protein histidine kinase activity
KAKIOLKG_00602 1.2e-228 2.7.13.3 T protein histidine kinase activity
KAKIOLKG_00603 0.0 S the current gene model (or a revised gene model) may contain a frame shift
KAKIOLKG_00604 2.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KAKIOLKG_00605 8.6e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KAKIOLKG_00606 1.9e-212 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KAKIOLKG_00607 1.8e-248 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
KAKIOLKG_00608 1.6e-180 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
KAKIOLKG_00609 7.9e-157 rssA S Phospholipase, patatin family
KAKIOLKG_00610 1.8e-102 estA E Lysophospholipase L1 and related esterases
KAKIOLKG_00611 2e-278 S unusual protein kinase
KAKIOLKG_00612 4.1e-38 S granule-associated protein
KAKIOLKG_00613 4.1e-283 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KAKIOLKG_00614 1.2e-195 S hmm pf01594
KAKIOLKG_00615 1.7e-102 G Belongs to the phosphoglycerate mutase family
KAKIOLKG_00616 3.1e-107 G Belongs to the phosphoglycerate mutase family
KAKIOLKG_00617 9.7e-109 pgm G Belongs to the phosphoglycerate mutase family
KAKIOLKG_00618 1.2e-149 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KAKIOLKG_00620 8.5e-177 wbbI M transferase activity, transferring glycosyl groups
KAKIOLKG_00621 1e-184 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
KAKIOLKG_00622 1.7e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
KAKIOLKG_00623 4.9e-244 epsU S Polysaccharide biosynthesis protein
KAKIOLKG_00624 1.5e-126 cps3F
KAKIOLKG_00625 3.6e-191 M Glycosyltransferase like family 2
KAKIOLKG_00626 3.4e-164
KAKIOLKG_00627 6.9e-121 Z012_10770 M Domain of unknown function (DUF1919)
KAKIOLKG_00628 4.4e-211 wcoF M Glycosyltransferase, group 1 family protein
KAKIOLKG_00629 3.1e-220 rgpAc GT4 M group 1 family protein
KAKIOLKG_00630 3.6e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KAKIOLKG_00631 5.9e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
KAKIOLKG_00632 3.5e-110 cps4C M biosynthesis protein
KAKIOLKG_00633 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KAKIOLKG_00634 1.2e-248 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KAKIOLKG_00635 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KAKIOLKG_00636 3.5e-134 yfeJ 6.3.5.2 F glutamine amidotransferase
KAKIOLKG_00637 1.5e-172 clcA_2 P Chloride transporter, ClC family
KAKIOLKG_00638 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KAKIOLKG_00639 6.2e-76 S Protein of unknown function (DUF1697)
KAKIOLKG_00640 4.7e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KAKIOLKG_00641 2.3e-119 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KAKIOLKG_00643 1.3e-09 V Glucan-binding protein C
KAKIOLKG_00644 8e-37 V Type III restriction enzyme, res subunit
KAKIOLKG_00645 1.3e-108 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KAKIOLKG_00646 9.3e-141 2.4.2.3 F Phosphorylase superfamily
KAKIOLKG_00647 7.5e-300 copA 3.6.3.54 P P-type ATPase
KAKIOLKG_00649 0.0 M Putative cell wall binding repeat
KAKIOLKG_00651 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KAKIOLKG_00652 1e-179 XK27_08075 M glycosyl transferase family 2
KAKIOLKG_00653 4.3e-98 S Carbohydrate-binding domain-containing protein Cthe_2159
KAKIOLKG_00654 3.7e-145 P molecular chaperone
KAKIOLKG_00655 3.8e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
KAKIOLKG_00657 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
KAKIOLKG_00658 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KAKIOLKG_00659 8.1e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KAKIOLKG_00660 4.8e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KAKIOLKG_00661 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KAKIOLKG_00662 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KAKIOLKG_00663 2.1e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KAKIOLKG_00664 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KAKIOLKG_00665 2.5e-178 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KAKIOLKG_00666 3.8e-193 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KAKIOLKG_00667 1e-58 XK27_08085
KAKIOLKG_00668 4.9e-144 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KAKIOLKG_00669 3.2e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KAKIOLKG_00670 5.5e-118 ylfI S tigr01906
KAKIOLKG_00671 4.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KAKIOLKG_00672 9.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
KAKIOLKG_00673 3.8e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
KAKIOLKG_00674 1.7e-30 KT response to antibiotic
KAKIOLKG_00676 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KAKIOLKG_00677 9.2e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KAKIOLKG_00678 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KAKIOLKG_00679 1.6e-257 S phospholipase Carboxylesterase
KAKIOLKG_00680 1.1e-200 yurR 1.4.5.1 E oxidoreductase
KAKIOLKG_00681 1.9e-93 zupT P Mediates zinc uptake. May also transport other divalent cations
KAKIOLKG_00682 1.2e-35 zupT P Mediates zinc uptake. May also transport other divalent cations
KAKIOLKG_00683 8.4e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KAKIOLKG_00684 6.9e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
KAKIOLKG_00685 1.3e-64 gtrA S GtrA-like protein
KAKIOLKG_00686 5.3e-248 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KAKIOLKG_00687 5.4e-162 ybbR S Protein conserved in bacteria
KAKIOLKG_00688 7.9e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KAKIOLKG_00689 7.6e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KAKIOLKG_00690 2.3e-150 cobQ S glutamine amidotransferase
KAKIOLKG_00691 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAKIOLKG_00692 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
KAKIOLKG_00693 1.6e-39 MA20_06245 S yiaA/B two helix domain
KAKIOLKG_00694 1.2e-92 uup S abc transporter atp-binding protein
KAKIOLKG_00695 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KAKIOLKG_00696 3.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KAKIOLKG_00697 0.0 dnaE 2.7.7.7 L DNA polymerase
KAKIOLKG_00698 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAKIOLKG_00699 4.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KAKIOLKG_00700 7.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KAKIOLKG_00701 2.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KAKIOLKG_00702 5.6e-55 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KAKIOLKG_00703 2e-70 S SnoaL-like polyketide cyclase
KAKIOLKG_00704 5.4e-53 hxlR K HxlR-like helix-turn-helix
KAKIOLKG_00705 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KAKIOLKG_00706 1.8e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KAKIOLKG_00708 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KAKIOLKG_00709 5.2e-96 ypmS S Protein conserved in bacteria
KAKIOLKG_00710 7.3e-158 ypmR E COG2755 Lysophospholipase L1 and related esterases
KAKIOLKG_00711 3e-148 DegV S DegV family
KAKIOLKG_00712 7.9e-302 recN L May be involved in recombinational repair of damaged DNA
KAKIOLKG_00713 2.4e-72 argR K Regulates arginine biosynthesis genes
KAKIOLKG_00714 3.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KAKIOLKG_00715 3.8e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KAKIOLKG_00716 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KAKIOLKG_00717 1.1e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KAKIOLKG_00719 1e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KAKIOLKG_00720 6.5e-125 dnaD
KAKIOLKG_00721 6.7e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KAKIOLKG_00722 1.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KAKIOLKG_00723 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KAKIOLKG_00724 3.1e-66 GnaT 2.5.1.16 K acetyltransferase
KAKIOLKG_00725 1.1e-19 Q Methyltransferase domain
KAKIOLKG_00726 2.4e-136 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KAKIOLKG_00727 1e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KAKIOLKG_00728 2.9e-111 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KAKIOLKG_00729 1.3e-243 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KAKIOLKG_00730 9.9e-229 rodA D Belongs to the SEDS family
KAKIOLKG_00731 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KAKIOLKG_00732 2.7e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KAKIOLKG_00733 9.8e-237 T PhoQ Sensor
KAKIOLKG_00734 1e-29 rpsT J Binds directly to 16S ribosomal RNA
KAKIOLKG_00735 1.9e-49 coaA 2.7.1.33 F Pantothenic acid kinase
KAKIOLKG_00736 1.3e-77 3.4.21.89 S RDD family
KAKIOLKG_00737 1.7e-63 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KAKIOLKG_00738 9.8e-49 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KAKIOLKG_00739 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KAKIOLKG_00740 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
KAKIOLKG_00741 2.2e-17 2.4.1.21 GT5 M Right handed beta helix region
KAKIOLKG_00742 6e-172 spd F DNA RNA non-specific endonuclease
KAKIOLKG_00743 1.1e-90 lemA S LemA family
KAKIOLKG_00744 1.3e-133 htpX O Belongs to the peptidase M48B family
KAKIOLKG_00745 9.1e-113 sirR K iron dependent repressor
KAKIOLKG_00746 9.5e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
KAKIOLKG_00747 6.6e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
KAKIOLKG_00748 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
KAKIOLKG_00749 4.7e-74 S Psort location CytoplasmicMembrane, score
KAKIOLKG_00750 3.6e-64 S Domain of unknown function (DUF4430)
KAKIOLKG_00751 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KAKIOLKG_00752 2.7e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
KAKIOLKG_00753 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KAKIOLKG_00754 2.5e-160 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KAKIOLKG_00755 1e-103 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
KAKIOLKG_00756 3.8e-85 dps P Belongs to the Dps family
KAKIOLKG_00757 4.4e-79 perR P Belongs to the Fur family
KAKIOLKG_00758 7.1e-27 yqgQ S protein conserved in bacteria
KAKIOLKG_00759 1.9e-178 glk 2.7.1.2 G Glucokinase
KAKIOLKG_00760 0.0 typA T GTP-binding protein TypA
KAKIOLKG_00762 8.2e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KAKIOLKG_00763 8e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KAKIOLKG_00764 2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KAKIOLKG_00765 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KAKIOLKG_00766 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KAKIOLKG_00767 3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KAKIOLKG_00768 2.2e-86 sepF D cell septum assembly
KAKIOLKG_00769 5e-30 yggT D integral membrane protein
KAKIOLKG_00770 8e-143 ylmH S conserved protein, contains S4-like domain
KAKIOLKG_00771 8.4e-138 divIVA D Cell division initiation protein
KAKIOLKG_00772 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KAKIOLKG_00773 4.2e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAKIOLKG_00774 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KAKIOLKG_00775 2.2e-34 nrdH O Glutaredoxin
KAKIOLKG_00776 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KAKIOLKG_00777 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KAKIOLKG_00778 5.3e-119 liaI S membrane
KAKIOLKG_00779 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
KAKIOLKG_00780 1.3e-302 KT response to antibiotic
KAKIOLKG_00781 5.3e-111 yebC M Membrane
KAKIOLKG_00782 1.2e-258 XK27_03190 S hydrolases of the HAD superfamily
KAKIOLKG_00783 2.2e-179 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KAKIOLKG_00785 2.9e-31 yozG K Transcriptional regulator
KAKIOLKG_00789 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KAKIOLKG_00790 1.6e-181 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KAKIOLKG_00791 8.3e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KAKIOLKG_00792 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAKIOLKG_00793 2.8e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KAKIOLKG_00794 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KAKIOLKG_00796 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
KAKIOLKG_00797 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KAKIOLKG_00798 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KAKIOLKG_00799 3.9e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
KAKIOLKG_00800 2.9e-179 scrR K Transcriptional regulator
KAKIOLKG_00801 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KAKIOLKG_00802 1.7e-61 yqhY S protein conserved in bacteria
KAKIOLKG_00803 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KAKIOLKG_00804 1.8e-70 comEB 3.5.4.12 F ComE operon protein 2
KAKIOLKG_00805 7e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KAKIOLKG_00806 4.7e-32 blpT
KAKIOLKG_00810 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KAKIOLKG_00811 4.2e-167 corA P COG0598 Mg2 and Co2 transporters
KAKIOLKG_00812 8.5e-122 XK27_01040 S Protein of unknown function (DUF1129)
KAKIOLKG_00814 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KAKIOLKG_00815 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KAKIOLKG_00816 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KAKIOLKG_00817 3.6e-41 XK27_05745
KAKIOLKG_00818 3.5e-224 mutY L A G-specific adenine glycosylase
KAKIOLKG_00819 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KAKIOLKG_00820 7.7e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KAKIOLKG_00825 1.1e-105 mreC M Involved in formation and maintenance of cell shape
KAKIOLKG_00826 6.1e-83 mreD M rod shape-determining protein MreD
KAKIOLKG_00827 4.1e-84 usp 3.5.1.28 CBM50 S CHAP domain
KAKIOLKG_00828 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAKIOLKG_00829 2.5e-217 araT 2.6.1.1 E Aminotransferase
KAKIOLKG_00830 8e-140 recO L Involved in DNA repair and RecF pathway recombination
KAKIOLKG_00831 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KAKIOLKG_00832 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAKIOLKG_00833 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KAKIOLKG_00834 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KAKIOLKG_00835 5.1e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KAKIOLKG_00836 4.2e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KAKIOLKG_00837 1.7e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KAKIOLKG_00838 5.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KAKIOLKG_00840 7.8e-157 S CHAP domain
KAKIOLKG_00841 1.6e-238 purD 6.3.4.13 F Belongs to the GARS family
KAKIOLKG_00842 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KAKIOLKG_00843 2.7e-202 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KAKIOLKG_00844 1.4e-173 1.1.1.169 H Ketopantoate reductase
KAKIOLKG_00845 3.3e-33
KAKIOLKG_00846 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KAKIOLKG_00847 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KAKIOLKG_00848 3.4e-68 argR K Regulates arginine biosynthesis genes
KAKIOLKG_00849 5.3e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KAKIOLKG_00850 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KAKIOLKG_00851 5.7e-77 S Protein of unknown function (DUF3021)
KAKIOLKG_00852 1.6e-68 K LytTr DNA-binding domain
KAKIOLKG_00854 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KAKIOLKG_00856 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KAKIOLKG_00857 5.6e-103 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KAKIOLKG_00858 4.5e-225 cinA 3.5.1.42 S Belongs to the CinA family
KAKIOLKG_00859 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KAKIOLKG_00860 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KAKIOLKG_00861 4.3e-116 K sequence-specific DNA binding
KAKIOLKG_00862 4e-153 V ABC transporter, ATP-binding protein
KAKIOLKG_00863 5.2e-93 S ABC-2 family transporter protein
KAKIOLKG_00864 2.5e-175 cbiM P biosynthesis protein CbiM
KAKIOLKG_00865 9.2e-136 P cobalt transport protein
KAKIOLKG_00866 6.3e-131 cbiO P ABC transporter
KAKIOLKG_00867 3.1e-137 ET ABC transporter substrate-binding protein
KAKIOLKG_00868 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
KAKIOLKG_00869 5.9e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KAKIOLKG_00870 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KAKIOLKG_00871 8e-99 metI P ABC transporter (Permease
KAKIOLKG_00872 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KAKIOLKG_00873 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KAKIOLKG_00874 3e-93 S UPF0397 protein
KAKIOLKG_00875 6.7e-309 ykoD P abc transporter atp-binding protein
KAKIOLKG_00876 2e-149 cbiQ P cobalt transport
KAKIOLKG_00877 3.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
KAKIOLKG_00878 9.8e-234 P COG0168 Trk-type K transport systems, membrane components
KAKIOLKG_00879 3.2e-127 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KAKIOLKG_00880 3.4e-89 yceD K metal-binding, possibly nucleic acid-binding protein
KAKIOLKG_00881 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KAKIOLKG_00882 6.6e-279 T PhoQ Sensor
KAKIOLKG_00883 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KAKIOLKG_00884 4.4e-214 dnaB L Replication initiation and membrane attachment
KAKIOLKG_00885 1.3e-165 dnaI L Primosomal protein DnaI
KAKIOLKG_00886 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KAKIOLKG_00887 1e-113
KAKIOLKG_00888 3.1e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KAKIOLKG_00889 7.2e-62 manO S protein conserved in bacteria
KAKIOLKG_00890 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
KAKIOLKG_00891 6.5e-116 manM G pts system
KAKIOLKG_00892 4.9e-174 manL 2.7.1.191 G pts system
KAKIOLKG_00893 7.7e-67 manO S Protein conserved in bacteria
KAKIOLKG_00894 1.4e-159 manN G PTS system mannose fructose sorbose family IID component
KAKIOLKG_00895 4.8e-132 manY G pts system
KAKIOLKG_00896 2.4e-168 manL 2.7.1.191 G pts system
KAKIOLKG_00897 4.6e-137 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KAKIOLKG_00898 1.9e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KAKIOLKG_00899 1.6e-247 pbuO S permease
KAKIOLKG_00900 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KAKIOLKG_00901 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
KAKIOLKG_00902 1e-176 brpA K Transcriptional
KAKIOLKG_00903 1.7e-105 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KAKIOLKG_00904 8.9e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KAKIOLKG_00905 1.9e-66 ytxH S General stress protein
KAKIOLKG_00907 6.8e-178 yegQ O Peptidase U32
KAKIOLKG_00908 6.4e-251 yegQ O Peptidase U32
KAKIOLKG_00909 1.1e-87 bioY S biotin synthase
KAKIOLKG_00911 1.1e-33 XK27_12190 S protein conserved in bacteria
KAKIOLKG_00912 8.1e-233 mntH P H( )-stimulated, divalent metal cation uptake system
KAKIOLKG_00913 1.9e-12
KAKIOLKG_00914 2.5e-65 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
KAKIOLKG_00915 0.0 L helicase
KAKIOLKG_00916 2.6e-12
KAKIOLKG_00917 8.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KAKIOLKG_00918 2.4e-136 M LysM domain
KAKIOLKG_00919 8.4e-23
KAKIOLKG_00920 5.2e-175 S hydrolase
KAKIOLKG_00922 9.6e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
KAKIOLKG_00923 5.1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KAKIOLKG_00924 9.4e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
KAKIOLKG_00925 1.7e-26 P Hemerythrin HHE cation binding domain protein
KAKIOLKG_00926 7.3e-155 5.2.1.8 G hydrolase
KAKIOLKG_00927 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KAKIOLKG_00928 6.2e-197 MA20_36090 S Protein of unknown function (DUF2974)
KAKIOLKG_00929 1.6e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KAKIOLKG_00930 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KAKIOLKG_00931 7.2e-91
KAKIOLKG_00932 2.4e-107 L Reverse transcriptase (RNA-dependent DNA polymerase)
KAKIOLKG_00933 1e-93 3.1.21.3 V Type I restriction modification DNA specificity domain
KAKIOLKG_00934 6.4e-55 S Phage derived protein Gp49-like (DUF891)
KAKIOLKG_00935 6.5e-42 K Helix-turn-helix domain
KAKIOLKG_00936 3.6e-304 hsdM 2.1.1.72 V type I restriction-modification system
KAKIOLKG_00937 2.8e-136 S double-stranded DNA endodeoxyribonuclease activity
KAKIOLKG_00939 7e-28 2.4.1.21 GT5 M Right handed beta helix region
KAKIOLKG_00940 0.0 zmpB M signal peptide protein, YSIRK family
KAKIOLKG_00941 0.0 GM domain, Protein
KAKIOLKG_00942 1.1e-52 S Tetratricopeptide repeat
KAKIOLKG_00943 8.4e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KAKIOLKG_00944 0.0 sbcC L ATPase involved in DNA repair
KAKIOLKG_00945 0.0 M family 8
KAKIOLKG_00946 9.5e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
KAKIOLKG_00947 8.5e-290 asp1 S Accessory Sec system protein Asp1
KAKIOLKG_00948 2.6e-291 asp2 3.4.11.5 S Accessory Sec system protein Asp2
KAKIOLKG_00949 3.8e-78 asp3 S Accessory Sec system protein Asp3
KAKIOLKG_00950 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KAKIOLKG_00951 1.4e-281 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KAKIOLKG_00952 2.1e-244 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KAKIOLKG_00953 2.6e-17 S Accessory secretory protein Sec Asp4
KAKIOLKG_00954 3.6e-16 S Accessory secretory protein Sec, Asp5
KAKIOLKG_00955 3.6e-185 nss M transferase activity, transferring glycosyl groups
KAKIOLKG_00956 1.3e-305 sraP UW Hep Hag repeat protein
KAKIOLKG_00957 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KAKIOLKG_00958 5.4e-184 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KAKIOLKG_00959 1.3e-176 bglC K Transcriptional regulator
KAKIOLKG_00960 1.5e-14 L COG3547 Transposase and inactivated derivatives
KAKIOLKG_00961 2e-42 mccF V LD-carboxypeptidase
KAKIOLKG_00962 3.2e-153 endA F DNA RNA non-specific endonuclease
KAKIOLKG_00963 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
KAKIOLKG_00964 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KAKIOLKG_00966 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KAKIOLKG_00967 8.3e-135 G Domain of unknown function (DUF4832)
KAKIOLKG_00968 2.7e-83 S membrane
KAKIOLKG_00969 3e-96 P VTC domain
KAKIOLKG_00970 1e-222 cotH M CotH kinase protein
KAKIOLKG_00971 1.6e-181 pelG M Putative exopolysaccharide Exporter (EPS-E)
KAKIOLKG_00972 6.1e-271 pelF GT4 M Domain of unknown function (DUF3492)
KAKIOLKG_00973 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
KAKIOLKG_00974 5.2e-146
KAKIOLKG_00975 2.3e-275 5.1.3.2 GM Psort location CytoplasmicMembrane, score
KAKIOLKG_00976 3.5e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KAKIOLKG_00977 1.6e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KAKIOLKG_00978 5.2e-298 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KAKIOLKG_00979 2.3e-87 ytsP 1.8.4.14 T GAF domain-containing protein
KAKIOLKG_00980 6.5e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KAKIOLKG_00981 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
KAKIOLKG_00984 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KAKIOLKG_00985 5.6e-212 XK27_05110 P Chloride transporter ClC family
KAKIOLKG_00986 5.6e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KAKIOLKG_00987 4.6e-280 clcA P Chloride transporter, ClC family
KAKIOLKG_00988 1e-75 fld C Flavodoxin
KAKIOLKG_00989 2.2e-18 XK27_08880
KAKIOLKG_00990 1.6e-126 XK27_08875 O Zinc-dependent metalloprotease
KAKIOLKG_00991 9.5e-149 estA CE1 S Esterase
KAKIOLKG_00992 7.8e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KAKIOLKG_00993 2e-135 XK27_08845 S abc transporter atp-binding protein
KAKIOLKG_00994 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KAKIOLKG_00995 2.2e-126 XK27_08835 S ABC transporter substrate binding protein
KAKIOLKG_00996 2.5e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KAKIOLKG_00997 1.1e-228 malX G ABC transporter
KAKIOLKG_00998 7.3e-178 malR K Transcriptional regulator
KAKIOLKG_00999 2.1e-301 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KAKIOLKG_01000 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KAKIOLKG_01001 1.2e-38
KAKIOLKG_01002 8.8e-184 lplA 6.3.1.20 H Lipoate-protein ligase
KAKIOLKG_01003 6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KAKIOLKG_01004 0.0 pepN 3.4.11.2 E aminopeptidase
KAKIOLKG_01005 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
KAKIOLKG_01006 1.5e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KAKIOLKG_01007 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KAKIOLKG_01008 1.3e-154 pstA P phosphate transport system permease
KAKIOLKG_01009 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
KAKIOLKG_01010 3.1e-156 pstS P phosphate
KAKIOLKG_01011 5.5e-250 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KAKIOLKG_01012 1.3e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KAKIOLKG_01013 1.5e-43 yktA S Belongs to the UPF0223 family
KAKIOLKG_01014 7.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KAKIOLKG_01015 4.3e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KAKIOLKG_01016 4e-145 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KAKIOLKG_01017 2e-239 XK27_04775 S hemerythrin HHE cation binding domain
KAKIOLKG_01018 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
KAKIOLKG_01019 6.2e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KAKIOLKG_01020 9.4e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KAKIOLKG_01021 2.5e-138 S haloacid dehalogenase-like hydrolase
KAKIOLKG_01022 1.5e-239 metY 2.5.1.49 E o-acetylhomoserine
KAKIOLKG_01023 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KAKIOLKG_01024 1.1e-237 agcS E (Alanine) symporter
KAKIOLKG_01025 4.1e-135 S dextransucrase activity
KAKIOLKG_01026 0.0 S dextransucrase activity
KAKIOLKG_01027 0.0 M Putative cell wall binding repeat
KAKIOLKG_01029 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KAKIOLKG_01030 3.1e-162 mleP S auxin efflux carrier
KAKIOLKG_01031 2.2e-309 sfcA 1.1.1.38, 4.1.1.101 C malic enzyme
KAKIOLKG_01032 2.1e-47 K Cro/C1-type HTH DNA-binding domain
KAKIOLKG_01033 2.6e-118 mleR K malolactic fermentation system
KAKIOLKG_01034 6.6e-131 XK27_00785 S CAAX protease self-immunity
KAKIOLKG_01035 4.3e-237 EGP Major facilitator Superfamily
KAKIOLKG_01036 1.8e-66 rmaI K Transcriptional regulator, MarR family
KAKIOLKG_01037 1.5e-88 maa 2.3.1.79 GK Maltose O-acetyltransferase
KAKIOLKG_01038 1.7e-134 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
KAKIOLKG_01039 0.0 3.5.1.28 M domain protein
KAKIOLKG_01040 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KAKIOLKG_01041 4.3e-15
KAKIOLKG_01042 4.9e-08 sraP UW domain, Protein
KAKIOLKG_01043 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KAKIOLKG_01044 1.6e-96 comFC K competence protein
KAKIOLKG_01045 3.7e-246 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KAKIOLKG_01046 7.7e-109 yvyE 3.4.13.9 S YigZ family
KAKIOLKG_01047 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KAKIOLKG_01048 6e-112 acuB S CBS domain
KAKIOLKG_01049 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KAKIOLKG_01050 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KAKIOLKG_01051 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
KAKIOLKG_01052 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KAKIOLKG_01053 2.6e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KAKIOLKG_01054 1.9e-46 ylbG S UPF0298 protein
KAKIOLKG_01055 2.2e-73 ylbF S Belongs to the UPF0342 family
KAKIOLKG_01056 1.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KAKIOLKG_01057 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KAKIOLKG_01058 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
KAKIOLKG_01059 3.4e-292 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
KAKIOLKG_01060 2.5e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KAKIOLKG_01061 2.6e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
KAKIOLKG_01062 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KAKIOLKG_01063 4.8e-288 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KAKIOLKG_01064 4.5e-269 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KAKIOLKG_01065 5e-99 yvdD 3.2.2.10 S Belongs to the LOG family
KAKIOLKG_01066 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KAKIOLKG_01067 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KAKIOLKG_01068 8e-42 ylxQ J ribosomal protein
KAKIOLKG_01069 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KAKIOLKG_01070 2.4e-196 nusA K Participates in both transcription termination and antitermination
KAKIOLKG_01071 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
KAKIOLKG_01072 2.6e-124 agrA KT phosphorelay signal transduction system
KAKIOLKG_01073 4.8e-201 2.7.13.3 T protein histidine kinase activity
KAKIOLKG_01075 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KAKIOLKG_01076 1.5e-36 ylqC L Belongs to the UPF0109 family
KAKIOLKG_01077 9.7e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KAKIOLKG_01078 0.0 ydaO E amino acid
KAKIOLKG_01079 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
KAKIOLKG_01080 4.5e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KAKIOLKG_01081 2.7e-290 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KAKIOLKG_01082 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KAKIOLKG_01083 3.7e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KAKIOLKG_01084 2.1e-168 murB 1.3.1.98 M cell wall formation
KAKIOLKG_01085 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KAKIOLKG_01086 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
KAKIOLKG_01087 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
KAKIOLKG_01088 4.4e-205 potD P spermidine putrescine ABC transporter
KAKIOLKG_01089 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
KAKIOLKG_01090 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
KAKIOLKG_01091 9.8e-158 GK ROK family
KAKIOLKG_01092 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KAKIOLKG_01093 1e-104 wecD M Acetyltransferase (GNAT) domain
KAKIOLKG_01094 1.2e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KAKIOLKG_01095 7.8e-72 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KAKIOLKG_01096 7e-59 arsC 1.20.4.1 P Belongs to the ArsC family
KAKIOLKG_01098 1e-55 lrgA S Effector of murein hydrolase LrgA
KAKIOLKG_01099 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KAKIOLKG_01100 1.8e-93 3.1.3.18 S IA, variant 1
KAKIOLKG_01101 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KAKIOLKG_01102 7.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KAKIOLKG_01103 4.5e-112 serB 3.1.3.3 E phosphoserine phosphatase
KAKIOLKG_01104 8.5e-08 N PFAM Uncharacterised protein family UPF0150
KAKIOLKG_01105 3.7e-149 EG Permeases of the drug metabolite transporter (DMT) superfamily
KAKIOLKG_01107 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KAKIOLKG_01108 6.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KAKIOLKG_01109 1.5e-126 K DNA-binding helix-turn-helix protein
KAKIOLKG_01110 1.7e-90 niaR S small molecule binding protein (contains 3H domain)
KAKIOLKG_01111 2.7e-86
KAKIOLKG_01112 3.8e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KAKIOLKG_01113 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KAKIOLKG_01114 7.7e-126 gntR1 K transcriptional
KAKIOLKG_01115 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KAKIOLKG_01116 5.5e-101 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KAKIOLKG_01117 7.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
KAKIOLKG_01118 2.1e-45
KAKIOLKG_01119 5.8e-51
KAKIOLKG_01120 2.6e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAKIOLKG_01121 4.6e-157 aatB ET ABC transporter substrate-binding protein
KAKIOLKG_01122 8.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
KAKIOLKG_01123 5.3e-105 artQ P ABC transporter (Permease
KAKIOLKG_01124 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
KAKIOLKG_01125 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KAKIOLKG_01126 8.4e-165 cpsY K Transcriptional regulator
KAKIOLKG_01127 1.6e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
KAKIOLKG_01128 1.1e-165 yeiH S Membrane
KAKIOLKG_01130 2.6e-09
KAKIOLKG_01131 5.2e-284 adcA P Belongs to the bacterial solute-binding protein 9 family
KAKIOLKG_01132 2.8e-143 XK27_10720 D peptidase activity
KAKIOLKG_01133 9.3e-272 pepD E Dipeptidase
KAKIOLKG_01134 5.7e-161 whiA K May be required for sporulation
KAKIOLKG_01135 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KAKIOLKG_01136 5.5e-161 rapZ S Displays ATPase and GTPase activities
KAKIOLKG_01137 6.1e-132 yejC S cyclic nucleotide-binding protein
KAKIOLKG_01138 3.1e-199 D nuclear chromosome segregation
KAKIOLKG_01139 4.6e-78 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KAKIOLKG_01140 5.1e-82 S Short repeat of unknown function (DUF308)
KAKIOLKG_01141 5e-90 K sequence-specific DNA binding
KAKIOLKG_01142 1.1e-157 L Replication initiation factor
KAKIOLKG_01143 1.4e-18 S Domain of unknown function (DUF3173)
KAKIOLKG_01144 8.5e-215 int L Belongs to the 'phage' integrase family
KAKIOLKG_01146 1.8e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KAKIOLKG_01147 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KAKIOLKG_01148 6.3e-44 yrzL S Belongs to the UPF0297 family
KAKIOLKG_01149 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KAKIOLKG_01150 3.2e-44 yrzB S Belongs to the UPF0473 family
KAKIOLKG_01151 3.1e-290 ccs S the current gene model (or a revised gene model) may contain a frame shift
KAKIOLKG_01152 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KAKIOLKG_01153 1.7e-13
KAKIOLKG_01154 1.6e-88 XK27_10930 K acetyltransferase
KAKIOLKG_01155 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAKIOLKG_01156 4.7e-123 yaaA S Belongs to the UPF0246 family
KAKIOLKG_01157 9.3e-167 XK27_01785 S cog cog1284
KAKIOLKG_01158 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KAKIOLKG_01160 2.5e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
KAKIOLKG_01161 8.3e-233 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KAKIOLKG_01162 7.3e-219 metE 2.1.1.14 E Methionine synthase
KAKIOLKG_01163 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KAKIOLKG_01164 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KAKIOLKG_01165 1.3e-06
KAKIOLKG_01168 5.3e-115 nudL L hydrolase
KAKIOLKG_01169 6.3e-54 K transcriptional regulator, PadR family
KAKIOLKG_01170 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
KAKIOLKG_01171 2.8e-106 S Putative adhesin
KAKIOLKG_01172 7.3e-160 XK27_06930 V domain protein
KAKIOLKG_01173 2.4e-95 XK27_06935 K transcriptional regulator
KAKIOLKG_01174 4.1e-54 ypaA M Membrane
KAKIOLKG_01175 1.9e-10
KAKIOLKG_01176 4.5e-67 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KAKIOLKG_01177 7.8e-88 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KAKIOLKG_01178 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KAKIOLKG_01179 1.3e-114 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KAKIOLKG_01180 5.9e-89 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KAKIOLKG_01181 4.1e-93 panT S ECF transporter, substrate-specific component
KAKIOLKG_01182 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KAKIOLKG_01183 3.6e-165 metF 1.5.1.20 E reductase
KAKIOLKG_01184 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KAKIOLKG_01186 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KAKIOLKG_01187 7.2e-113 apt 2.4.2.22, 2.4.2.7 F TRSP domain C terminus to PRTase_2
KAKIOLKG_01188 3.4e-144 stiP J Phosphoribosyl transferase (PRTase)
KAKIOLKG_01189 4.9e-197 yceG S Putative component of 'biosynthetic module'
KAKIOLKG_01190 1.6e-165 yceH P Belongs to the TelA family
KAKIOLKG_01191 1.2e-90 T proteins involved in stress response, homologs of TerZ and
KAKIOLKG_01192 2.3e-77 T proteins involved in stress response, homologs of TerZ and
KAKIOLKG_01193 2.8e-90 T proteins involved in stress response, homologs of TerZ and
KAKIOLKG_01194 0.0 3.6.3.8 P cation transport ATPase
KAKIOLKG_01195 1.8e-75 3.1.3.12 S hydrolases of the HAD superfamily
KAKIOLKG_01196 1.9e-91 G Citrate lyase beta subunit
KAKIOLKG_01197 1.3e-243 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KAKIOLKG_01198 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KAKIOLKG_01199 6.9e-234 dltB M Membrane protein involved in D-alanine export
KAKIOLKG_01200 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KAKIOLKG_01201 8.6e-181 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KAKIOLKG_01202 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KAKIOLKG_01203 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KAKIOLKG_01204 7.8e-152 yvjA S membrane
KAKIOLKG_01205 5.1e-306 ybiT S abc transporter atp-binding protein
KAKIOLKG_01206 0.0 XK27_10405 S Bacterial membrane protein YfhO
KAKIOLKG_01210 2.4e-119 yoaK S Protein of unknown function (DUF1275)
KAKIOLKG_01211 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KAKIOLKG_01212 3.5e-206 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KAKIOLKG_01213 6.5e-134 parB K Belongs to the ParB family
KAKIOLKG_01214 4.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KAKIOLKG_01215 4.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KAKIOLKG_01216 1.1e-29 yyzM S Protein conserved in bacteria
KAKIOLKG_01217 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KAKIOLKG_01218 8.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KAKIOLKG_01219 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KAKIOLKG_01220 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KAKIOLKG_01221 3e-60 divIC D Septum formation initiator
KAKIOLKG_01223 1.5e-236 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KAKIOLKG_01224 7.7e-233 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KAKIOLKG_01225 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KAKIOLKG_01226 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KAKIOLKG_01227 1.1e-204 L Transposase IS116 IS110 IS902
KAKIOLKG_01228 4.1e-59 3.4.17.14 M lysozyme activity
KAKIOLKG_01229 8.8e-11 L transposition
KAKIOLKG_01231 3.9e-87 sigH K DNA-templated transcription, initiation
KAKIOLKG_01232 1.8e-134 ykuT M mechanosensitive ion channel
KAKIOLKG_01233 3.4e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KAKIOLKG_01234 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KAKIOLKG_01235 1.1e-308 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KAKIOLKG_01236 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
KAKIOLKG_01237 1.2e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KAKIOLKG_01238 8.5e-176 prmA J Ribosomal protein L11 methyltransferase
KAKIOLKG_01239 2.6e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KAKIOLKG_01240 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KAKIOLKG_01241 2.2e-81 nrdI F Belongs to the NrdI family
KAKIOLKG_01242 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KAKIOLKG_01243 2.2e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KAKIOLKG_01244 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KAKIOLKG_01245 1.5e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KAKIOLKG_01246 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KAKIOLKG_01247 3.8e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KAKIOLKG_01248 2.2e-181 yhjX P Major Facilitator
KAKIOLKG_01249 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KAKIOLKG_01250 5.8e-82 V VanZ like family
KAKIOLKG_01251 2.1e-184 D nuclear chromosome segregation
KAKIOLKG_01252 2.2e-123 glnQ E abc transporter atp-binding protein
KAKIOLKG_01253 2.7e-272 glnP P ABC transporter
KAKIOLKG_01254 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KAKIOLKG_01255 1.1e-17 S Protein of unknown function (DUF3021)
KAKIOLKG_01256 2e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KAKIOLKG_01257 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
KAKIOLKG_01258 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KAKIOLKG_01259 6.9e-234 sufD O assembly protein SufD
KAKIOLKG_01260 5.9e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KAKIOLKG_01261 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
KAKIOLKG_01262 2.9e-273 sufB O assembly protein SufB
KAKIOLKG_01263 4.7e-26
KAKIOLKG_01264 1.8e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KAKIOLKG_01265 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KAKIOLKG_01266 1e-70 adcR K transcriptional
KAKIOLKG_01267 7.1e-135 adcC P ABC transporter, ATP-binding protein
KAKIOLKG_01268 1.9e-128 adcB P ABC transporter (Permease
KAKIOLKG_01269 1.8e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KAKIOLKG_01270 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KAKIOLKG_01271 3.1e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
KAKIOLKG_01272 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
KAKIOLKG_01273 9.3e-153 Z012_04635 K sequence-specific DNA binding
KAKIOLKG_01274 1.2e-278 V ABC transporter
KAKIOLKG_01275 6.1e-126 yeeN K transcriptional regulatory protein
KAKIOLKG_01276 1.7e-46 yajC U protein transport
KAKIOLKG_01277 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KAKIOLKG_01278 5.5e-144 cdsA 2.7.7.41 S Belongs to the CDS family
KAKIOLKG_01279 7.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KAKIOLKG_01280 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KAKIOLKG_01281 0.0 WQ51_06230 S ABC transporter
KAKIOLKG_01282 1.4e-142 cmpC S abc transporter atp-binding protein
KAKIOLKG_01283 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KAKIOLKG_01284 3.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KAKIOLKG_01286 5.5e-44
KAKIOLKG_01287 5.8e-55 S TM2 domain
KAKIOLKG_01288 4.7e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KAKIOLKG_01289 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KAKIOLKG_01290 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KAKIOLKG_01291 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
KAKIOLKG_01292 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KAKIOLKG_01293 2.4e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KAKIOLKG_01294 6.6e-145 cof S Sucrose-6F-phosphate phosphohydrolase
KAKIOLKG_01295 2.4e-136 glcR K transcriptional regulator (DeoR family)
KAKIOLKG_01296 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KAKIOLKG_01297 5.8e-74 K transcriptional
KAKIOLKG_01298 1.1e-231 S COG1073 Hydrolases of the alpha beta superfamily
KAKIOLKG_01299 2.1e-38 yjdF S Protein of unknown function (DUF2992)
KAKIOLKG_01300 3.9e-45 3.2.2.21 S YCII-related domain
KAKIOLKG_01301 4e-53 K regulation of RNA biosynthetic process
KAKIOLKG_01302 1.9e-153 cylA V abc transporter atp-binding protein
KAKIOLKG_01303 1.9e-131 cylB V ABC-2 type transporter
KAKIOLKG_01304 1.3e-73 K COG3279 Response regulator of the LytR AlgR family
KAKIOLKG_01305 2.2e-30 S Protein of unknown function (DUF3021)
KAKIOLKG_01306 1.6e-123 mta K Transcriptional
KAKIOLKG_01307 2.4e-119 yhcA V abc transporter atp-binding protein
KAKIOLKG_01308 4.9e-208 macB_2 V FtsX-like permease family
KAKIOLKG_01309 8.7e-273 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KAKIOLKG_01310 2.6e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KAKIOLKG_01311 4.4e-74 yhaI S Protein of unknown function (DUF805)
KAKIOLKG_01312 1.2e-252 pepC 3.4.22.40 E aminopeptidase
KAKIOLKG_01313 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KAKIOLKG_01314 1.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KAKIOLKG_01315 5.8e-94 ypsA S Belongs to the UPF0398 family
KAKIOLKG_01316 9.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KAKIOLKG_01317 5.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KAKIOLKG_01318 2.7e-280 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KAKIOLKG_01319 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KAKIOLKG_01320 9.6e-23
KAKIOLKG_01321 5.2e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KAKIOLKG_01322 1.5e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
KAKIOLKG_01323 1.2e-301 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KAKIOLKG_01324 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KAKIOLKG_01325 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KAKIOLKG_01326 2.7e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KAKIOLKG_01327 6.7e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KAKIOLKG_01328 2.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KAKIOLKG_01329 3.6e-99 ybhL S Belongs to the BI1 family
KAKIOLKG_01330 1.1e-12 ycdA S Domain of unknown function (DUF4352)
KAKIOLKG_01331 8.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KAKIOLKG_01332 1.8e-90 K transcriptional regulator
KAKIOLKG_01333 1.6e-36 yneF S UPF0154 protein
KAKIOLKG_01334 1.7e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KAKIOLKG_01335 3.9e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KAKIOLKG_01336 3.9e-98 XK27_09740 S Phosphoesterase
KAKIOLKG_01337 8.3e-87 ykuL S CBS domain
KAKIOLKG_01338 1.5e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KAKIOLKG_01339 9e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KAKIOLKG_01340 3.4e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KAKIOLKG_01341 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KAKIOLKG_01342 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
KAKIOLKG_01343 9.3e-259 trkH P Cation transport protein
KAKIOLKG_01344 2.2e-246 trkA P Potassium transporter peripheral membrane component
KAKIOLKG_01345 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KAKIOLKG_01346 1.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KAKIOLKG_01347 4.4e-107 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KAKIOLKG_01348 1.2e-152 K sequence-specific DNA binding
KAKIOLKG_01349 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KAKIOLKG_01350 1.3e-54 yhaI L Membrane
KAKIOLKG_01351 2.7e-247 S Domain of unknown function (DUF4173)
KAKIOLKG_01352 2.2e-94 rocB E COG4187 Arginine degradation protein
KAKIOLKG_01354 6.7e-178 P ammonium transporter
KAKIOLKG_01355 7.4e-73 ureI S AmiS/UreI family transporter
KAKIOLKG_01356 1.2e-38 ureA 3.5.1.5 E Urease, gamma subunit
KAKIOLKG_01357 8.1e-44 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KAKIOLKG_01358 2e-292 ureC 3.5.1.5 E Amidohydrolase family
KAKIOLKG_01359 2e-50 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KAKIOLKG_01360 1.7e-67 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KAKIOLKG_01361 7.3e-96 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KAKIOLKG_01362 2.1e-77 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KAKIOLKG_01363 2.7e-24 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAKIOLKG_01364 7.4e-17 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KAKIOLKG_01365 0.0 XK27_10035 V abc transporter atp-binding protein
KAKIOLKG_01366 3.2e-290 yfiB1 V abc transporter atp-binding protein
KAKIOLKG_01367 1.4e-99 pvaA M lytic transglycosylase activity
KAKIOLKG_01368 3.2e-178 ndpA S 37-kD nucleoid-associated bacterial protein
KAKIOLKG_01369 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KAKIOLKG_01370 1.2e-60 XK27_05710 K Acetyltransferase (GNAT) domain
KAKIOLKG_01371 8e-95 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KAKIOLKG_01372 1.1e-142 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KAKIOLKG_01373 1.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KAKIOLKG_01374 3.9e-110 tdk 2.7.1.21 F thymidine kinase
KAKIOLKG_01375 1.3e-179 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KAKIOLKG_01376 7.1e-152 gst O Glutathione S-transferase
KAKIOLKG_01377 1.6e-174 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KAKIOLKG_01378 2.5e-172 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KAKIOLKG_01379 4.4e-45 rpmE2 J 50S ribosomal protein L31
KAKIOLKG_01380 4.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
KAKIOLKG_01381 7.6e-164 ypuA S secreted protein
KAKIOLKG_01382 4.5e-70 yaeR E COG0346 Lactoylglutathione lyase and related lyases
KAKIOLKG_01383 7.9e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KAKIOLKG_01384 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KAKIOLKG_01385 3.5e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KAKIOLKG_01386 7.8e-255 noxE P NADH oxidase
KAKIOLKG_01388 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KAKIOLKG_01389 0.0 pepO 3.4.24.71 O Peptidase family M13
KAKIOLKG_01390 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KAKIOLKG_01391 5.8e-288 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
KAKIOLKG_01392 3.9e-125 treR K trehalose operon
KAKIOLKG_01393 1.9e-95 ywlG S Belongs to the UPF0340 family
KAKIOLKG_01395 4.8e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
KAKIOLKG_01397 1.5e-239 6.3.2.2 H gamma-glutamylcysteine synthetase
KAKIOLKG_01398 4.4e-62 rplQ J ribosomal protein l17
KAKIOLKG_01399 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KAKIOLKG_01400 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KAKIOLKG_01401 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KAKIOLKG_01402 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KAKIOLKG_01403 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KAKIOLKG_01404 2.5e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KAKIOLKG_01405 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KAKIOLKG_01406 5.7e-58 rplO J binds to the 23S rRNA
KAKIOLKG_01407 1.9e-23 rpmD J ribosomal protein l30
KAKIOLKG_01408 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KAKIOLKG_01409 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KAKIOLKG_01410 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KAKIOLKG_01411 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KAKIOLKG_01412 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KAKIOLKG_01413 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KAKIOLKG_01414 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KAKIOLKG_01415 1.9e-113 yxeN P ABC transporter, permease protein
KAKIOLKG_01416 1.3e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
KAKIOLKG_01417 0.0 S dextransucrase activity
KAKIOLKG_01418 1.1e-213 yfnA E amino acid
KAKIOLKG_01419 6.8e-51 XK27_01300 S ASCH
KAKIOLKG_01420 3.5e-115 S Carbohydrate-binding domain-containing protein Cthe_2159
KAKIOLKG_01421 1.8e-16 csbD S CsbD-like
KAKIOLKG_01422 6e-101 S Protein of unknown function (DUF421)
KAKIOLKG_01423 2e-58 S Protein of unknown function (DUF3290)
KAKIOLKG_01424 5.1e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
KAKIOLKG_01425 5.8e-231 brnQ E Component of the transport system for branched-chain amino acids
KAKIOLKG_01426 3.3e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KAKIOLKG_01428 7.9e-244 norM V Multidrug efflux pump
KAKIOLKG_01429 1.4e-145 K sequence-specific DNA binding
KAKIOLKG_01430 5.3e-271 V (ABC) transporter
KAKIOLKG_01431 3.8e-224 pbuX F xanthine permease
KAKIOLKG_01432 2.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KAKIOLKG_01433 6.9e-33
KAKIOLKG_01434 3e-14 S integral membrane protein
KAKIOLKG_01435 2.1e-42 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
KAKIOLKG_01436 1e-107 yhfC S Putative membrane peptidase family (DUF2324)
KAKIOLKG_01438 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KAKIOLKG_01440 3.6e-245 S dextransucrase activity
KAKIOLKG_01441 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
KAKIOLKG_01442 2.1e-100 S dextransucrase activity
KAKIOLKG_01443 9.3e-119 M Putative cell wall binding repeat
KAKIOLKG_01444 4.5e-105 S dextransucrase activity
KAKIOLKG_01445 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KAKIOLKG_01446 2.4e-81 yecS P ABC transporter (Permease
KAKIOLKG_01447 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
KAKIOLKG_01448 5.2e-241 nylA 3.5.1.4 J Belongs to the amidase family
KAKIOLKG_01449 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KAKIOLKG_01450 7.7e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KAKIOLKG_01451 4.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KAKIOLKG_01452 1.5e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KAKIOLKG_01453 1.8e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KAKIOLKG_01454 1.2e-133 S TraX protein
KAKIOLKG_01455 4.3e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KAKIOLKG_01458 2.7e-24 K Cro/C1-type HTH DNA-binding domain
KAKIOLKG_01459 4.3e-262 S Psort location CytoplasmicMembrane, score
KAKIOLKG_01460 9e-232 dinF V Mate efflux family protein
KAKIOLKG_01461 4.6e-177 yclQ P ABC-type enterochelin transport system, periplasmic component
KAKIOLKG_01462 2.1e-151 S von Willebrand factor (vWF) type A domain
KAKIOLKG_01463 6.2e-48 mccF V LD-carboxypeptidase
KAKIOLKG_01464 9.5e-297 O MreB/Mbl protein
KAKIOLKG_01466 5.8e-146 V Psort location CytoplasmicMembrane, score
KAKIOLKG_01469 5.8e-13
KAKIOLKG_01470 1.5e-226 dcuS 2.7.13.3 T protein histidine kinase activity
KAKIOLKG_01471 2.4e-232 2.7.13.3 T protein histidine kinase activity
KAKIOLKG_01472 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KAKIOLKG_01473 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KAKIOLKG_01474 6.8e-125 S Protein of unknown function (DUF554)
KAKIOLKG_01475 1.5e-132 ecsA_2 V abc transporter atp-binding protein
KAKIOLKG_01476 1.6e-251 XK27_00765
KAKIOLKG_01477 2.2e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KAKIOLKG_01478 1.8e-221 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KAKIOLKG_01479 5.4e-34 yhaI J Protein of unknown function (DUF805)
KAKIOLKG_01480 1.3e-61 yhaI J Protein of unknown function (DUF805)
KAKIOLKG_01481 2.2e-32 yhaI J Protein of unknown function (DUF805)
KAKIOLKG_01484 9.7e-96
KAKIOLKG_01485 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KAKIOLKG_01486 2.4e-45 ftsL D cell division protein FtsL
KAKIOLKG_01487 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KAKIOLKG_01488 1.4e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KAKIOLKG_01489 1.1e-219 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KAKIOLKG_01490 7.4e-253 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KAKIOLKG_01491 1.8e-61 yutD J protein conserved in bacteria
KAKIOLKG_01492 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KAKIOLKG_01493 6.7e-90 XK27_09885 V Glycopeptide antibiotics resistance protein
KAKIOLKG_01495 0.0 mdlA V abc transporter atp-binding protein
KAKIOLKG_01496 0.0 mdlB V abc transporter atp-binding protein
KAKIOLKG_01505 3.1e-44 spiA K sequence-specific DNA binding
KAKIOLKG_01506 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KAKIOLKG_01507 5.7e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KAKIOLKG_01508 1e-106 V CAAX protease self-immunity
KAKIOLKG_01509 2.7e-140 cppA E CppA N-terminal
KAKIOLKG_01510 3.7e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KAKIOLKG_01512 1.2e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KAKIOLKG_01513 1.6e-143 cah 4.2.1.1 P carbonic anhydrase
KAKIOLKG_01514 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KAKIOLKG_01515 2.8e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KAKIOLKG_01516 4.7e-35
KAKIOLKG_01517 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KAKIOLKG_01518 1.8e-162 yxeN P ABC transporter (Permease
KAKIOLKG_01519 1.6e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
KAKIOLKG_01520 5e-10 S Protein of unknown function (DUF4059)
KAKIOLKG_01521 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KAKIOLKG_01522 1.6e-91 rsmD 2.1.1.171 L Methyltransferase
KAKIOLKG_01523 1.1e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KAKIOLKG_01524 6.4e-188 ylbL T Belongs to the peptidase S16 family
KAKIOLKG_01525 5.1e-181 yhcC S radical SAM protein
KAKIOLKG_01526 5.9e-97 ytqB J (SAM)-dependent
KAKIOLKG_01528 0.0 yjcE P NhaP-type Na H and K H antiporters
KAKIOLKG_01529 1.1e-23
KAKIOLKG_01531 3.6e-140 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KAKIOLKG_01532 1.7e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KAKIOLKG_01533 7.4e-10 MU outer membrane autotransporter barrel domain protein
KAKIOLKG_01534 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KAKIOLKG_01536 9e-75 XK27_03180 T universal stress protein
KAKIOLKG_01537 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KAKIOLKG_01538 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KAKIOLKG_01539 2e-100 pncA Q isochorismatase
KAKIOLKG_01540 4.4e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KAKIOLKG_01541 2.1e-216 M lipopolysaccharide 3-alpha-galactosyltransferase activity
KAKIOLKG_01542 9.7e-158 H COG0463 Glycosyltransferases involved in cell wall biogenesis
KAKIOLKG_01543 1.7e-187 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KAKIOLKG_01544 3.1e-233 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KAKIOLKG_01545 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KAKIOLKG_01546 1.7e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KAKIOLKG_01547 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KAKIOLKG_01549 2.2e-58
KAKIOLKG_01550 4.3e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KAKIOLKG_01551 2.2e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KAKIOLKG_01552 5.1e-98 yqeG S hydrolase of the HAD superfamily
KAKIOLKG_01553 5.4e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KAKIOLKG_01554 2.3e-48 yhbY J RNA-binding protein
KAKIOLKG_01555 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KAKIOLKG_01556 2.9e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KAKIOLKG_01557 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KAKIOLKG_01558 2.9e-139 yqeM Q Methyltransferase domain protein
KAKIOLKG_01559 2.5e-195 ylbM S Belongs to the UPF0348 family
KAKIOLKG_01560 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KAKIOLKG_01562 2.5e-54
KAKIOLKG_01563 3.6e-57 S CD20-like family
KAKIOLKG_01564 3.4e-225 L Transposase
KAKIOLKG_01566 1.1e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KAKIOLKG_01567 3.2e-130 ecsA V abc transporter atp-binding protein
KAKIOLKG_01568 3.2e-176 ecsB U Bacterial ABC transporter protein EcsB
KAKIOLKG_01569 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
KAKIOLKG_01570 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KAKIOLKG_01572 2.1e-213 ytfP S Flavoprotein
KAKIOLKG_01573 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KAKIOLKG_01574 2.1e-63 XK27_02560 S cog cog2151
KAKIOLKG_01575 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
KAKIOLKG_01576 1.1e-104 dnaQ 2.7.7.7 L DNA polymerase III
KAKIOLKG_01577 1.3e-120 K transcriptional regulator, MerR family
KAKIOLKG_01578 0.0 V ABC transporter (Permease
KAKIOLKG_01579 1.9e-124 V abc transporter atp-binding protein
KAKIOLKG_01581 3.9e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KAKIOLKG_01582 1.8e-47
KAKIOLKG_01583 1.9e-116 gltJ P ABC transporter (Permease
KAKIOLKG_01584 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KAKIOLKG_01585 1.5e-33 ykzG S Belongs to the UPF0356 family
KAKIOLKG_01586 1.6e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KAKIOLKG_01587 1.7e-70 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KAKIOLKG_01588 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KAKIOLKG_01589 9.7e-113 azlC E AzlC protein
KAKIOLKG_01590 1.3e-46 azlD S branched-chain amino acid
KAKIOLKG_01591 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KAKIOLKG_01592 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KAKIOLKG_01593 3.2e-153 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KAKIOLKG_01594 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KAKIOLKG_01595 3e-93 cvpA S toxin biosynthetic process
KAKIOLKG_01596 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KAKIOLKG_01597 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KAKIOLKG_01599 3.1e-53 CP_0034 A G5
KAKIOLKG_01601 2.5e-30
KAKIOLKG_01603 1.2e-180 L Transposase
KAKIOLKG_01604 3.4e-34 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KAKIOLKG_01605 2.6e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KAKIOLKG_01606 1.5e-36 L RePlication protein
KAKIOLKG_01607 4.6e-28 glnQ 3.6.3.21 E abc transporter atp-binding protein
KAKIOLKG_01608 1.2e-146 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KAKIOLKG_01609 6.8e-113 pscB M CHAP domain protein
KAKIOLKG_01610 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
KAKIOLKG_01611 2.5e-62 glnR K Transcriptional regulator
KAKIOLKG_01612 3e-87 S Fusaric acid resistance protein-like
KAKIOLKG_01613 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KAKIOLKG_01614 1.5e-86
KAKIOLKG_01615 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
KAKIOLKG_01616 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KAKIOLKG_01617 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KAKIOLKG_01618 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KAKIOLKG_01619 5.3e-142 purR 2.4.2.7 F operon repressor
KAKIOLKG_01620 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
KAKIOLKG_01621 3.2e-170 rmuC S RmuC domain protein
KAKIOLKG_01622 8.6e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
KAKIOLKG_01623 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KAKIOLKG_01624 2.1e-160 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KAKIOLKG_01626 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KAKIOLKG_01627 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KAKIOLKG_01628 3.6e-143 tatD L Hydrolase, tatd
KAKIOLKG_01629 2.7e-73 yccU S CoA-binding protein
KAKIOLKG_01630 2.4e-50 trxA O Belongs to the thioredoxin family
KAKIOLKG_01631 1.4e-139 S Macro domain protein
KAKIOLKG_01632 3e-61 L thioesterase
KAKIOLKG_01633 1.6e-52 bta 1.8.1.8 CO cell redox homeostasis
KAKIOLKG_01635 1e-174 pdhD 1.8.1.4 C Dehydrogenase
KAKIOLKG_01636 8.1e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
KAKIOLKG_01637 1.3e-174 acoB C dehydrogenase E1 component
KAKIOLKG_01638 4.2e-143 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KAKIOLKG_01639 6.4e-81 Q Methyltransferase domain
KAKIOLKG_01640 1e-62 K TetR family transcriptional regulator
KAKIOLKG_01641 8.4e-48
KAKIOLKG_01642 4e-128 V CAAX protease self-immunity
KAKIOLKG_01643 9.8e-10
KAKIOLKG_01644 3.1e-21 M Bacterial lipoprotein
KAKIOLKG_01645 8.3e-61 S Protein of unknown function (DUF1722)
KAKIOLKG_01646 9.7e-64 yqeB S Pyrimidine dimer DNA glycosylase
KAKIOLKG_01648 4.7e-50
KAKIOLKG_01649 6.4e-92 S CAAX protease self-immunity
KAKIOLKG_01650 1.1e-115 estA E GDSL-like Lipase/Acylhydrolase
KAKIOLKG_01651 1.1e-102
KAKIOLKG_01652 1.6e-286 sulP P Sulfate permease and related transporters (MFS superfamily)
KAKIOLKG_01653 6.4e-148 ycgQ S TIGR03943 family
KAKIOLKG_01654 1.2e-155 XK27_03015 S permease
KAKIOLKG_01656 0.0 yhgF K Transcriptional accessory protein
KAKIOLKG_01657 2.2e-41 pspC KT PspC domain
KAKIOLKG_01658 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KAKIOLKG_01659 1.8e-47 veg S Biofilm formation stimulator VEG
KAKIOLKG_01660 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KAKIOLKG_01661 2.2e-73 rplI J binds to the 23S rRNA
KAKIOLKG_01662 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KAKIOLKG_01663 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KAKIOLKG_01664 2.4e-99 yvbG U UPF0056 membrane protein
KAKIOLKG_01665 1.9e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KAKIOLKG_01666 1.2e-310 S Bacterial membrane protein, YfhO
KAKIOLKG_01667 1.4e-58 isaA GH23 M Immunodominant staphylococcal antigen A
KAKIOLKG_01668 9.1e-72 lytE M LysM domain protein
KAKIOLKG_01669 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KAKIOLKG_01670 4.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KAKIOLKG_01671 1.4e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KAKIOLKG_01672 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KAKIOLKG_01673 3.7e-130 S sequence-specific DNA binding
KAKIOLKG_01674 3.3e-231 ymfH S Peptidase M16
KAKIOLKG_01675 6.7e-229 ymfF S Peptidase M16
KAKIOLKG_01676 4.9e-58 yaaA S S4 domain protein YaaA
KAKIOLKG_01677 5.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KAKIOLKG_01678 1.2e-174 yubA S permease
KAKIOLKG_01679 1.6e-90 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KAKIOLKG_01680 2.1e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KAKIOLKG_01681 3.2e-124 ftsE D cell division ATP-binding protein FtsE
KAKIOLKG_01682 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KAKIOLKG_01683 3.5e-205 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KAKIOLKG_01684 1.4e-153 yjjH S Calcineurin-like phosphoesterase
KAKIOLKG_01685 1.2e-129 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KAKIOLKG_01686 0.0 pacL 3.6.3.8 P cation transport ATPase
KAKIOLKG_01687 9.1e-68 ywiB S Domain of unknown function (DUF1934)
KAKIOLKG_01688 1.3e-146 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
KAKIOLKG_01689 4.6e-146 yidA S hydrolases of the HAD superfamily
KAKIOLKG_01690 1.5e-225 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KAKIOLKG_01691 1.1e-56 S Protein of unknown function (DUF454)
KAKIOLKG_01692 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KAKIOLKG_01693 5.4e-220 vicK 2.7.13.3 T Histidine kinase
KAKIOLKG_01694 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KAKIOLKG_01695 3.9e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
KAKIOLKG_01696 2.2e-143 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KAKIOLKG_01697 1.3e-98 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KAKIOLKG_01699 5.8e-11
KAKIOLKG_01700 2.3e-191 XK27_10075 S abc transporter atp-binding protein
KAKIOLKG_01701 0.0 V abc transporter atp-binding protein
KAKIOLKG_01702 1.7e-299 V abc transporter atp-binding protein
KAKIOLKG_01703 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KAKIOLKG_01705 6.6e-287 S Protein of unknown function (DUF3114)
KAKIOLKG_01706 1.1e-98 2.3.1.128 K Acetyltransferase GNAT Family
KAKIOLKG_01707 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KAKIOLKG_01708 8.3e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KAKIOLKG_01709 5.7e-187 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
KAKIOLKG_01710 9.8e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KAKIOLKG_01711 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KAKIOLKG_01712 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KAKIOLKG_01713 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KAKIOLKG_01714 6.6e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KAKIOLKG_01715 2.7e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KAKIOLKG_01716 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KAKIOLKG_01719 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KAKIOLKG_01720 1.6e-169 vraS 2.7.13.3 T Histidine kinase
KAKIOLKG_01721 3.6e-115 yvqF S Membrane
KAKIOLKG_01722 4.8e-97 kcsA P Ion transport protein
KAKIOLKG_01723 1.4e-294 prkC 2.7.11.1 KLT serine threonine protein kinase
KAKIOLKG_01724 1.3e-134 stp 3.1.3.16 T phosphatase
KAKIOLKG_01725 7.8e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KAKIOLKG_01726 2.8e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KAKIOLKG_01727 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KAKIOLKG_01728 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KAKIOLKG_01729 4.4e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KAKIOLKG_01730 8.3e-196 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KAKIOLKG_01731 3.3e-144 XK27_02985 S overlaps another CDS with the same product name
KAKIOLKG_01732 1.4e-147 supH S overlaps another CDS with the same product name
KAKIOLKG_01733 5.6e-62 yvoA_1 K Transcriptional
KAKIOLKG_01734 2.7e-118 skfE V abc transporter atp-binding protein
KAKIOLKG_01735 2.4e-128 V Psort location CytoplasmicMembrane, score
KAKIOLKG_01736 2.8e-171 oppF P Belongs to the ABC transporter superfamily
KAKIOLKG_01737 1.8e-201 oppD P Belongs to the ABC transporter superfamily
KAKIOLKG_01738 1.7e-165 amiD P ABC transporter (Permease
KAKIOLKG_01739 1.1e-275 amiC P ABC transporter (Permease
KAKIOLKG_01740 5.5e-311 amiA E ABC transporter, substrate-binding protein, family 5
KAKIOLKG_01741 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KAKIOLKG_01742 1e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KAKIOLKG_01743 1.8e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KAKIOLKG_01744 8.3e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KAKIOLKG_01745 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KAKIOLKG_01746 2.4e-101 yjbK S Adenylate cyclase
KAKIOLKG_01747 8.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KAKIOLKG_01748 1.9e-203 iscS 2.8.1.7 E Cysteine desulfurase
KAKIOLKG_01749 1.4e-59 XK27_04120 S Putative amino acid metabolism
KAKIOLKG_01750 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KAKIOLKG_01751 3.7e-128 puuD T peptidase C26
KAKIOLKG_01752 1.2e-118 radC E Belongs to the UPF0758 family
KAKIOLKG_01753 1.5e-300 rgpF M Rhamnan synthesis protein F
KAKIOLKG_01754 1.6e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KAKIOLKG_01755 8.9e-142 rgpC GM Transport permease protein
KAKIOLKG_01756 5.4e-175 rgpB GT2 M Glycosyltransferase, group 2 family protein
KAKIOLKG_01757 1.8e-225 rgpA GT4 M Domain of unknown function (DUF1972)
KAKIOLKG_01758 6e-230 GT4 M transferase activity, transferring glycosyl groups
KAKIOLKG_01759 1.1e-220 M Psort location CytoplasmicMembrane, score
KAKIOLKG_01760 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
KAKIOLKG_01761 1.1e-122
KAKIOLKG_01762 3.2e-149 2.4.1.60 S Glycosyltransferase group 2 family protein
KAKIOLKG_01763 1.9e-43 S Uncharacterized conserved protein (DUF2304)
KAKIOLKG_01764 7e-127 arnC M group 2 family protein
KAKIOLKG_01765 1.3e-176 cpsIaJ S Glycosyltransferase like family 2
KAKIOLKG_01766 5.1e-157 M Glycosyltransferase, group 2 family protein
KAKIOLKG_01767 9.3e-226 amrA S membrane protein involved in the export of O-antigen and teichoic acid
KAKIOLKG_01768 1.7e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KAKIOLKG_01769 1.5e-259 S Glucosyl transferase GtrII
KAKIOLKG_01770 1.4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KAKIOLKG_01771 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KAKIOLKG_01772 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KAKIOLKG_01773 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KAKIOLKG_01774 4.2e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KAKIOLKG_01775 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KAKIOLKG_01776 6.1e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
KAKIOLKG_01777 2.8e-210 arcT 2.6.1.1 E Aminotransferase
KAKIOLKG_01778 1.7e-137 ET Belongs to the bacterial solute-binding protein 3 family
KAKIOLKG_01779 7.1e-139 ET ABC transporter
KAKIOLKG_01780 1.4e-83 mutT 3.6.1.55 F Nudix family
KAKIOLKG_01781 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KAKIOLKG_01783 3.6e-163 S CAAX amino terminal protease family protein
KAKIOLKG_01784 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KAKIOLKG_01785 1.1e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
KAKIOLKG_01786 1.7e-17 XK27_00735
KAKIOLKG_01787 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KAKIOLKG_01789 5.8e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KAKIOLKG_01790 5.7e-10 O ADP-ribosylglycohydrolase
KAKIOLKG_01791 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
KAKIOLKG_01792 5.4e-62 ycaO O OsmC-like protein
KAKIOLKG_01793 1.4e-107 magIII L Base excision DNA repair protein, HhH-GPD family
KAKIOLKG_01794 5e-263 proWX P ABC transporter
KAKIOLKG_01795 7.5e-124 proV E abc transporter atp-binding protein
KAKIOLKG_01796 8.1e-146 1.6.5.2 GM epimerase
KAKIOLKG_01797 2e-66 mgrA K Transcriptional regulator, MarR family
KAKIOLKG_01798 3.1e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KAKIOLKG_01799 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KAKIOLKG_01802 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KAKIOLKG_01804 4.1e-72 XK27_01300 P Protein conserved in bacteria
KAKIOLKG_01805 2.3e-79 FNV0100 F Belongs to the Nudix hydrolase family
KAKIOLKG_01806 1.8e-136 IQ Acetoin reductase
KAKIOLKG_01807 1.3e-42 pspE P Rhodanese-like protein
KAKIOLKG_01808 4.2e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KAKIOLKG_01809 3.2e-222 XK27_05470 E Methionine synthase
KAKIOLKG_01810 3.1e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KAKIOLKG_01811 9.2e-216 T PhoQ Sensor
KAKIOLKG_01812 2.4e-121 KT Transcriptional regulatory protein, C terminal
KAKIOLKG_01814 1.9e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KAKIOLKG_01815 1.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KAKIOLKG_01816 0.0 lacS G transporter
KAKIOLKG_01817 0.0 lacL 3.2.1.23 G -beta-galactosidase
KAKIOLKG_01818 2.9e-210 S Tetratricopeptide repeat
KAKIOLKG_01819 1.6e-157 yvgN C reductase
KAKIOLKG_01820 1.9e-30 XK27_10490
KAKIOLKG_01821 2e-39 DJ nuclease activity
KAKIOLKG_01822 2.4e-111 yoaK S Protein of unknown function (DUF1275)
KAKIOLKG_01823 2.4e-110 drgA C nitroreductase
KAKIOLKG_01824 1.4e-124 T Xre family transcriptional regulator
KAKIOLKG_01825 1.2e-147 T PhoQ Sensor
KAKIOLKG_01826 2e-127 S ABC-2 family transporter protein
KAKIOLKG_01827 3.7e-168 bcrA V abc transporter atp-binding protein
KAKIOLKG_01828 5.6e-223 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KAKIOLKG_01829 1.8e-153 E Alpha/beta hydrolase of unknown function (DUF915)
KAKIOLKG_01830 8.9e-75 ywnA K Transcriptional regulator
KAKIOLKG_01831 1.5e-152 1.13.11.2 S glyoxalase
KAKIOLKG_01832 1.9e-111 K sequence-specific DNA binding
KAKIOLKG_01833 8.3e-85
KAKIOLKG_01834 5.2e-78 K Acetyltransferase (GNAT) domain
KAKIOLKG_01835 1.1e-141 S ABC-2 family transporter protein
KAKIOLKG_01836 2.6e-141 S ABC-2 family transporter protein
KAKIOLKG_01837 2e-183 S AAA domain, putative AbiEii toxin, Type IV TA system
KAKIOLKG_01838 9.7e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KAKIOLKG_01839 1e-180 desK 2.7.13.3 T Histidine kinase
KAKIOLKG_01840 9.9e-132 yvfS V ABC-2 type transporter
KAKIOLKG_01841 5.7e-158 XK27_09825 V 'abc transporter, ATP-binding protein
KAKIOLKG_01844 1e-134 yocS S Transporter
KAKIOLKG_01845 9.8e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
KAKIOLKG_01846 3.4e-132 yvfS V Transporter
KAKIOLKG_01847 2.8e-157 XK27_09825 V abc transporter atp-binding protein
KAKIOLKG_01848 2e-14 liaI KT membrane
KAKIOLKG_01849 7.6e-30 liaI KT membrane
KAKIOLKG_01850 1.4e-92 XK27_05000 S metal cluster binding
KAKIOLKG_01851 0.0 V ABC transporter (permease)
KAKIOLKG_01852 2.2e-134 macB2 V ABC transporter, ATP-binding protein
KAKIOLKG_01853 1e-163 T Histidine kinase
KAKIOLKG_01854 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KAKIOLKG_01857 6.8e-162 ppaC 3.6.1.1 C inorganic pyrophosphatase
KAKIOLKG_01858 9.2e-99 S Domain of unknown function (DUF1803)
KAKIOLKG_01859 7.8e-102 ygaC J Belongs to the UPF0374 family
KAKIOLKG_01860 9.2e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
KAKIOLKG_01861 6.9e-248 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KAKIOLKG_01862 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
KAKIOLKG_01863 8.2e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
KAKIOLKG_01864 3.5e-117 S HAD hydrolase, family IA, variant 3
KAKIOLKG_01865 4.8e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KAKIOLKG_01866 5.2e-72 marR K Transcriptional regulator, MarR family
KAKIOLKG_01867 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KAKIOLKG_01868 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KAKIOLKG_01869 7.5e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KAKIOLKG_01870 4.7e-163 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KAKIOLKG_01871 6.2e-126 IQ reductase
KAKIOLKG_01872 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KAKIOLKG_01873 6.2e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KAKIOLKG_01874 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KAKIOLKG_01875 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KAKIOLKG_01876 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KAKIOLKG_01877 7.9e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KAKIOLKG_01878 1.1e-80 queD 4.1.2.50, 4.2.3.12 H synthase
KAKIOLKG_01879 2.6e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KAKIOLKG_01880 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KAKIOLKG_01881 6.3e-19
KAKIOLKG_01882 2.7e-260 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KAKIOLKG_01883 6.3e-213 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KAKIOLKG_01884 8.4e-79 ypmB S Protein conserved in bacteria
KAKIOLKG_01885 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KAKIOLKG_01886 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KAKIOLKG_01887 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
KAKIOLKG_01888 8.6e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
KAKIOLKG_01889 1.4e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KAKIOLKG_01890 1.2e-191 tcsA S membrane
KAKIOLKG_01891 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KAKIOLKG_01892 2.1e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KAKIOLKG_01893 5e-232 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KAKIOLKG_01894 5.4e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
KAKIOLKG_01895 7.4e-12
KAKIOLKG_01897 5.3e-76 repA S Replication initiator protein A
KAKIOLKG_01898 3.6e-10
KAKIOLKG_01899 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KAKIOLKG_01900 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KAKIOLKG_01901 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KAKIOLKG_01902 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
KAKIOLKG_01903 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KAKIOLKG_01904 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KAKIOLKG_01905 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
KAKIOLKG_01906 1.4e-57 asp S cog cog1302
KAKIOLKG_01907 5.4e-226 norN V Mate efflux family protein
KAKIOLKG_01908 7.8e-277 thrC 4.2.3.1 E Threonine synthase
KAKIOLKG_01910 2.4e-47 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
KAKIOLKG_01911 4.5e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
KAKIOLKG_01912 6.3e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
KAKIOLKG_01913 1.2e-177 XK27_10475 S oxidoreductase
KAKIOLKG_01914 4.3e-200 gldA 1.1.1.6 C glycerol dehydrogenase
KAKIOLKG_01916 5e-284 XK27_07020 S Belongs to the UPF0371 family
KAKIOLKG_01917 7.8e-177 vex1 V Efflux ABC transporter, permease protein
KAKIOLKG_01918 1e-108 vex2 V abc transporter atp-binding protein
KAKIOLKG_01919 2.4e-235 vex3 V Efflux ABC transporter, permease protein
KAKIOLKG_01920 9.8e-115 K Response regulator receiver domain protein
KAKIOLKG_01921 8.5e-227 vncS 2.7.13.3 T Histidine kinase
KAKIOLKG_01922 4.9e-309 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
KAKIOLKG_01923 1.7e-182 galR K Transcriptional regulator
KAKIOLKG_01924 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KAKIOLKG_01925 2.9e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KAKIOLKG_01926 3.1e-78 feoA P FeoA domain protein
KAKIOLKG_01927 5.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
KAKIOLKG_01928 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KAKIOLKG_01929 1e-34 ykuJ S protein conserved in bacteria
KAKIOLKG_01930 6.9e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KAKIOLKG_01931 0.0 clpE O Belongs to the ClpA ClpB family
KAKIOLKG_01932 2.4e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KAKIOLKG_01933 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
KAKIOLKG_01934 7.5e-172 S oxidoreductase
KAKIOLKG_01935 4.4e-118 M Pfam SNARE associated Golgi protein
KAKIOLKG_01936 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
KAKIOLKG_01939 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
KAKIOLKG_01942 4.8e-16 S Protein of unknown function (DUF2969)
KAKIOLKG_01943 4.5e-199 ilvE 2.6.1.42 E Aminotransferase
KAKIOLKG_01944 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KAKIOLKG_01945 4e-10
KAKIOLKG_01947 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KAKIOLKG_01948 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KAKIOLKG_01949 2.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
KAKIOLKG_01950 2.2e-30 S Domain of unknown function (DUF1912)
KAKIOLKG_01951 3.2e-167 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KAKIOLKG_01952 4.4e-242 mmuP E amino acid
KAKIOLKG_01953 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KAKIOLKG_01954 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KAKIOLKG_01955 9.7e-22
KAKIOLKG_01956 1.9e-89 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KAKIOLKG_01957 2.7e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KAKIOLKG_01958 6.5e-210 mvaS 2.3.3.10 I synthase
KAKIOLKG_01959 1.2e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KAKIOLKG_01960 1.1e-77 K hmm pf08876
KAKIOLKG_01961 2.2e-117 yqfA K protein, Hemolysin III
KAKIOLKG_01962 4.1e-29 pspC KT PspC domain protein
KAKIOLKG_01963 2e-197 S Protein of unknown function (DUF3114)
KAKIOLKG_01964 3e-149 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KAKIOLKG_01965 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KAKIOLKG_01966 6.5e-13
KAKIOLKG_01967 5.7e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KAKIOLKG_01968 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KAKIOLKG_01969 0.0 U protein secretion
KAKIOLKG_01970 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KAKIOLKG_01971 4.6e-23
KAKIOLKG_01972 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KAKIOLKG_01973 3.7e-257 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KAKIOLKG_01974 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KAKIOLKG_01975 1.4e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KAKIOLKG_01976 9.2e-165 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KAKIOLKG_01977 3.4e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KAKIOLKG_01978 7.9e-152 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KAKIOLKG_01979 7.4e-103 GBS0088 J protein conserved in bacteria
KAKIOLKG_01980 1.7e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KAKIOLKG_01981 3e-179 ybdK T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KAKIOLKG_01982 9.8e-110 T Response regulator receiver domain protein
KAKIOLKG_01983 5.5e-50 T peptidase
KAKIOLKG_01984 4.4e-125 E alpha/beta hydrolase fold
KAKIOLKG_01986 7.5e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KAKIOLKG_01987 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KAKIOLKG_01988 2.7e-143 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KAKIOLKG_01989 1.7e-114 S VIT family
KAKIOLKG_01990 2.6e-135 deoD_1 2.4.2.3 F Phosphorylase superfamily
KAKIOLKG_01991 1.2e-21
KAKIOLKG_01992 1.6e-28 XK27_00085 K Transcriptional
KAKIOLKG_01993 6.9e-197 yceA S Belongs to the UPF0176 family
KAKIOLKG_01994 3.8e-120 sagI S ABC-2 type transporter
KAKIOLKG_01995 1.3e-162 V ABC transporter
KAKIOLKG_01996 2.4e-130 rr02 KT response regulator
KAKIOLKG_01997 1.1e-210 T signal transduction protein with a C-terminal ATPase domain
KAKIOLKG_01998 1.5e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KAKIOLKG_01999 9.6e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KAKIOLKG_02000 0.0 lmrA V abc transporter atp-binding protein
KAKIOLKG_02001 0.0 mdlB V abc transporter atp-binding protein
KAKIOLKG_02002 2.2e-274 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KAKIOLKG_02003 8.1e-108 abiGI K Transcriptional regulator, AbiEi antitoxin
KAKIOLKG_02004 5e-105 XK27_00530 M CHAP domain protein
KAKIOLKG_02005 1.3e-65 traG U COG3505 Type IV secretory pathway, VirD4 components
KAKIOLKG_02007 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KAKIOLKG_02008 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KAKIOLKG_02009 1.5e-209 V permease protein
KAKIOLKG_02010 2.2e-120 macB V ABC transporter, ATP-binding protein
KAKIOLKG_02011 8.8e-181 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KAKIOLKG_02012 3.9e-123 rsmJ 2.1.1.242 J Putative SAM-dependent methyltransferase
KAKIOLKG_02013 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KAKIOLKG_02014 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KAKIOLKG_02015 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KAKIOLKG_02016 1.8e-221 pyrP F uracil Permease
KAKIOLKG_02017 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KAKIOLKG_02018 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KAKIOLKG_02019 1.1e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KAKIOLKG_02020 4e-167 fhuR K transcriptional regulator (lysR family)
KAKIOLKG_02022 4.2e-67 K Helix-turn-helix

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)