ORF_ID e_value Gene_name EC_number CAZy COGs Description
DGMANHCO_00003 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DGMANHCO_00004 5.2e-198 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
DGMANHCO_00005 3.1e-14
DGMANHCO_00007 3.8e-201 M Glycosyltransferase like family 2
DGMANHCO_00008 8.2e-159 map 3.4.11.18 E Methionine Aminopeptidase
DGMANHCO_00009 7.2e-80 fld C Flavodoxin
DGMANHCO_00010 6e-180 yihY S Belongs to the UPF0761 family
DGMANHCO_00011 2.6e-258 S Uncharacterized protein conserved in bacteria (DUF2252)
DGMANHCO_00012 2.1e-111 K Bacterial regulatory proteins, tetR family
DGMANHCO_00013 2.7e-238 pepS E Thermophilic metalloprotease (M29)
DGMANHCO_00014 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DGMANHCO_00015 7.5e-07
DGMANHCO_00017 7.3e-71 S Domain of unknown function (DUF3284)
DGMANHCO_00018 7.6e-56 chbA 2.7.1.196, 2.7.1.205 G phosphoenolpyruvate-dependent sugar phosphotransferase system
DGMANHCO_00019 1.1e-223 yfmL 3.6.4.13 L DEAD DEAH box helicase
DGMANHCO_00020 2.5e-175 mocA S Oxidoreductase
DGMANHCO_00021 1.7e-60 S Domain of unknown function (DUF4828)
DGMANHCO_00022 2.2e-60 S Protein of unknown function (DUF1093)
DGMANHCO_00023 9.3e-138 lys M Glycosyl hydrolases family 25
DGMANHCO_00024 1.2e-28
DGMANHCO_00025 1.9e-119 qmcA O prohibitin homologues
DGMANHCO_00026 1.2e-165 degV S Uncharacterised protein, DegV family COG1307
DGMANHCO_00027 1.1e-78 K Acetyltransferase (GNAT) family
DGMANHCO_00028 5e-265 ydiC1 EGP Major facilitator Superfamily
DGMANHCO_00029 0.0 pepO 3.4.24.71 O Peptidase family M13
DGMANHCO_00030 1.5e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
DGMANHCO_00031 2e-144 cof S Sucrose-6F-phosphate phosphohydrolase
DGMANHCO_00032 3.6e-219 yttB EGP Major facilitator Superfamily
DGMANHCO_00033 1.3e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DGMANHCO_00034 4.4e-194 yegS 2.7.1.107 G Lipid kinase
DGMANHCO_00035 8e-279 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DGMANHCO_00036 5.1e-265 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DGMANHCO_00037 3.7e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DGMANHCO_00038 3.4e-211 camS S sex pheromone
DGMANHCO_00039 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DGMANHCO_00040 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DGMANHCO_00042 8.4e-27 yjgN S Bacterial protein of unknown function (DUF898)
DGMANHCO_00043 1.3e-129 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
DGMANHCO_00044 2e-190 S response to antibiotic
DGMANHCO_00046 1.2e-252 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
DGMANHCO_00047 1.3e-54
DGMANHCO_00048 1e-63
DGMANHCO_00049 1.5e-71 pheB 5.4.99.5 S Belongs to the UPF0735 family
DGMANHCO_00052 1.9e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DGMANHCO_00053 3.2e-80 ohrR K helix_turn_helix multiple antibiotic resistance protein
DGMANHCO_00054 8.2e-171 whiA K May be required for sporulation
DGMANHCO_00055 2.4e-192 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DGMANHCO_00056 9.7e-166 rapZ S Displays ATPase and GTPase activities
DGMANHCO_00057 8.7e-85 S Short repeat of unknown function (DUF308)
DGMANHCO_00058 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DGMANHCO_00059 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DGMANHCO_00060 6.5e-119 yfbR S HD containing hydrolase-like enzyme
DGMANHCO_00061 0.0 V FtsX-like permease family
DGMANHCO_00062 4.5e-91 V ABC transporter
DGMANHCO_00063 1.7e-174 T His Kinase A (phosphoacceptor) domain
DGMANHCO_00064 2.2e-114 T Transcriptional regulatory protein, C terminal
DGMANHCO_00065 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DGMANHCO_00066 2.4e-178 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DGMANHCO_00067 6.9e-195 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DGMANHCO_00068 9.5e-166 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DGMANHCO_00069 2.1e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DGMANHCO_00070 7.4e-34 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
DGMANHCO_00071 1.4e-30
DGMANHCO_00072 2.4e-262 yvlB S Putative adhesin
DGMANHCO_00073 1e-119 phoU P Plays a role in the regulation of phosphate uptake
DGMANHCO_00074 9.3e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DGMANHCO_00075 4.5e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DGMANHCO_00076 4.8e-157 pstA P Phosphate transport system permease protein PstA
DGMANHCO_00077 3.6e-155 pstC P probably responsible for the translocation of the substrate across the membrane
DGMANHCO_00078 1.2e-152 pstS P Phosphate
DGMANHCO_00079 1.1e-308 phoR 2.7.13.3 T Histidine kinase
DGMANHCO_00080 2.4e-130 K response regulator
DGMANHCO_00081 3.6e-202 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
DGMANHCO_00083 5.4e-124 ftsE D ABC transporter
DGMANHCO_00084 3.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DGMANHCO_00085 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DGMANHCO_00086 2.1e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DGMANHCO_00087 6.6e-82 comFC S Competence protein
DGMANHCO_00088 1.7e-235 comFA L Helicase C-terminal domain protein
DGMANHCO_00089 2.6e-115 yvyE 3.4.13.9 S YigZ family
DGMANHCO_00090 3.1e-231 rny S Endoribonuclease that initiates mRNA decay
DGMANHCO_00091 4.7e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DGMANHCO_00092 9.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
DGMANHCO_00093 4.3e-203 K Helix-turn-helix XRE-family like proteins
DGMANHCO_00094 4.8e-34 S Phospholipase_D-nuclease N-terminal
DGMANHCO_00095 1e-165 yxlF V ABC transporter
DGMANHCO_00096 2.7e-132 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
DGMANHCO_00097 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
DGMANHCO_00099 2.4e-99 K Bacteriophage CI repressor helix-turn-helix domain
DGMANHCO_00100 3.3e-258
DGMANHCO_00101 5.5e-141 T Calcineurin-like phosphoesterase superfamily domain
DGMANHCO_00102 2.4e-256 C COG0277 FAD FMN-containing dehydrogenases
DGMANHCO_00103 1e-36
DGMANHCO_00104 4.8e-42 S Protein of unknown function (DUF2089)
DGMANHCO_00105 1.8e-181 I PAP2 superfamily
DGMANHCO_00106 7.3e-208 mccF V LD-carboxypeptidase
DGMANHCO_00107 1.5e-42
DGMANHCO_00108 4e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DGMANHCO_00109 2.6e-88 ogt 2.1.1.63 L Methyltransferase
DGMANHCO_00110 1.1e-192 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DGMANHCO_00111 2.3e-42
DGMANHCO_00112 3.2e-81 slyA K Transcriptional regulator
DGMANHCO_00113 2e-161 1.6.5.5 C alcohol dehydrogenase
DGMANHCO_00114 2e-53 ypaA S Protein of unknown function (DUF1304)
DGMANHCO_00115 1.4e-41 S Protein of unknown function (DUF1516)
DGMANHCO_00116 9.1e-254 pbuO S permease
DGMANHCO_00117 6.3e-46 S DsrE/DsrF-like family
DGMANHCO_00118 1.7e-179 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DGMANHCO_00119 4.9e-29
DGMANHCO_00120 5.8e-103 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DGMANHCO_00121 0.0
DGMANHCO_00123 1.3e-121 S WxL domain surface cell wall-binding
DGMANHCO_00124 3.8e-123 S WxL domain surface cell wall-binding
DGMANHCO_00125 1.1e-182 ynjC S Cell surface protein
DGMANHCO_00127 1.7e-268 L Mga helix-turn-helix domain
DGMANHCO_00128 7.7e-172 yhaI S Protein of unknown function (DUF805)
DGMANHCO_00129 1.2e-57
DGMANHCO_00130 1.1e-253 rarA L recombination factor protein RarA
DGMANHCO_00131 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DGMANHCO_00132 1.1e-158 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
DGMANHCO_00133 3.2e-138 magIII L Base excision DNA repair protein, HhH-GPD family
DGMANHCO_00134 4e-47 S Thiamine-binding protein
DGMANHCO_00135 1.3e-245 yhgE V domain protein
DGMANHCO_00136 1e-99 yobS K Bacterial regulatory proteins, tetR family
DGMANHCO_00137 1.1e-254 bmr3 EGP Major facilitator Superfamily
DGMANHCO_00139 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
DGMANHCO_00140 1.4e-104 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DGMANHCO_00141 1.3e-109 ymfM S Helix-turn-helix domain
DGMANHCO_00142 2e-129 IQ Enoyl-(Acyl carrier protein) reductase
DGMANHCO_00143 3.4e-244 ymfH S Peptidase M16
DGMANHCO_00144 9.4e-231 ymfF S Peptidase M16 inactive domain protein
DGMANHCO_00145 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
DGMANHCO_00146 8.4e-72 WQ51_03320 S Protein of unknown function (DUF1149)
DGMANHCO_00147 9.4e-97 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DGMANHCO_00148 9.6e-155 rrmA 2.1.1.187 H Methyltransferase
DGMANHCO_00149 5.7e-172 corA P CorA-like Mg2+ transporter protein
DGMANHCO_00150 5.7e-191 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DGMANHCO_00151 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DGMANHCO_00152 2.5e-62 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
DGMANHCO_00153 4.6e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
DGMANHCO_00154 2.1e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DGMANHCO_00155 1.5e-112 cutC P Participates in the control of copper homeostasis
DGMANHCO_00156 4.1e-203 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DGMANHCO_00157 1.1e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
DGMANHCO_00158 4.6e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DGMANHCO_00159 1.3e-122 yjbM 2.7.6.5 S RelA SpoT domain protein
DGMANHCO_00160 7.5e-106 yjbK S CYTH
DGMANHCO_00161 2.3e-113 yjbH Q Thioredoxin
DGMANHCO_00162 4.3e-213 coiA 3.6.4.12 S Competence protein
DGMANHCO_00163 2.1e-244 XK27_08635 S UPF0210 protein
DGMANHCO_00164 1e-38 gcvR T Belongs to the UPF0237 family
DGMANHCO_00165 2.5e-258 cpdA S Calcineurin-like phosphoesterase
DGMANHCO_00166 3.9e-234 malY 4.4.1.8 E Aminotransferase, class I
DGMANHCO_00169 3.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
DGMANHCO_00170 9.3e-305 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
DGMANHCO_00171 1.5e-288 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
DGMANHCO_00173 2.8e-93 FNV0100 F NUDIX domain
DGMANHCO_00174 4.8e-143 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DGMANHCO_00175 4e-33 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
DGMANHCO_00176 2.2e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DGMANHCO_00177 2.2e-280 ytgP S Polysaccharide biosynthesis protein
DGMANHCO_00178 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DGMANHCO_00179 2.4e-119 3.6.1.27 I Acid phosphatase homologues
DGMANHCO_00180 5.2e-109 S Domain of unknown function (DUF4811)
DGMANHCO_00181 6.2e-266 lmrB EGP Major facilitator Superfamily
DGMANHCO_00182 4.3e-80 merR K MerR HTH family regulatory protein
DGMANHCO_00183 3.8e-263 emrY EGP Major facilitator Superfamily
DGMANHCO_00184 1.1e-209 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DGMANHCO_00185 3.9e-71
DGMANHCO_00189 2.6e-95 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DGMANHCO_00190 6.7e-136 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DGMANHCO_00191 5.5e-107 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DGMANHCO_00192 1.2e-124 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DGMANHCO_00193 2e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DGMANHCO_00194 4.8e-165 xerD D recombinase XerD
DGMANHCO_00195 4.9e-162 cvfB S S1 domain
DGMANHCO_00196 1.5e-72 yeaL S Protein of unknown function (DUF441)
DGMANHCO_00197 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DGMANHCO_00198 7e-178 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DGMANHCO_00199 0.0 dnaE 2.7.7.7 L DNA polymerase
DGMANHCO_00200 2.5e-18 S Protein of unknown function (DUF2929)
DGMANHCO_00201 2.4e-135
DGMANHCO_00202 4.7e-301 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
DGMANHCO_00203 2.8e-94 M1-874 K Domain of unknown function (DUF1836)
DGMANHCO_00204 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DGMANHCO_00205 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DGMANHCO_00206 4.1e-48 yrvD S Lipopolysaccharide assembly protein A domain
DGMANHCO_00207 1e-142 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
DGMANHCO_00208 8.6e-184 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DGMANHCO_00209 0.0 oatA I Acyltransferase
DGMANHCO_00210 3.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DGMANHCO_00211 6.6e-131 fruR K DeoR C terminal sensor domain
DGMANHCO_00212 6.7e-170 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DGMANHCO_00213 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
DGMANHCO_00214 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DGMANHCO_00215 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DGMANHCO_00216 1.5e-259 arpJ P ABC transporter permease
DGMANHCO_00217 1.3e-20
DGMANHCO_00218 7.8e-48 MA20_27270 S mazG nucleotide pyrophosphohydrolase
DGMANHCO_00219 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
DGMANHCO_00220 1.9e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DGMANHCO_00221 1.3e-222 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DGMANHCO_00222 0.0 yknV V ABC transporter
DGMANHCO_00223 4.5e-40 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DGMANHCO_00224 8.7e-225 ptsG G phosphotransferase system
DGMANHCO_00225 8e-171 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DGMANHCO_00226 6.9e-221 yagE E Amino acid permease
DGMANHCO_00227 7.7e-25
DGMANHCO_00228 4.4e-94 M1-431 S Protein of unknown function (DUF1706)
DGMANHCO_00229 3e-96 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
DGMANHCO_00230 4.8e-35 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
DGMANHCO_00231 1.9e-121 dpiA KT cheY-homologous receiver domain
DGMANHCO_00232 1.1e-286 dpiB 2.7.13.3 T Single cache domain 3
DGMANHCO_00233 4e-224 maeN C 2-hydroxycarboxylate transporter family
DGMANHCO_00234 1.4e-212 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
DGMANHCO_00235 2.2e-35 yjdF S Protein of unknown function (DUF2992)
DGMANHCO_00236 4.3e-114 S Bacteriocin-protection, YdeI or OmpD-Associated
DGMANHCO_00237 2.7e-255 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
DGMANHCO_00238 2.2e-145 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
DGMANHCO_00239 4.8e-90 maa 2.3.1.79 S Maltose acetyltransferase
DGMANHCO_00240 1.1e-214 lsgC M Glycosyl transferases group 1
DGMANHCO_00241 2.3e-306 yebA E Transglutaminase/protease-like homologues
DGMANHCO_00242 3e-184 yeaD S Protein of unknown function DUF58
DGMANHCO_00243 6e-142 yeaC S ATPase family associated with various cellular activities (AAA)
DGMANHCO_00244 1.5e-80 S Uncharacterised protein family (UPF0236)
DGMANHCO_00246 6.7e-105 S Stage II sporulation protein M
DGMANHCO_00247 3.7e-99 ydaF J Acetyltransferase (GNAT) domain
DGMANHCO_00248 2.1e-266 glnP P ABC transporter
DGMANHCO_00249 1.5e-264 glnP P ABC transporter
DGMANHCO_00250 3.4e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DGMANHCO_00251 4.3e-166 yniA G Phosphotransferase enzyme family
DGMANHCO_00252 9.1e-144 S AAA ATPase domain
DGMANHCO_00253 3.7e-269 ydbT S Bacterial PH domain
DGMANHCO_00254 1e-68 S Bacterial PH domain
DGMANHCO_00255 1e-51
DGMANHCO_00256 4.9e-41 yqkB S Iron-sulphur cluster biosynthesis
DGMANHCO_00257 2.2e-128 S Protein of unknown function (DUF975)
DGMANHCO_00258 3.5e-09 G Bacterial extracellular solute-binding protein
DGMANHCO_00259 1.7e-218 G Bacterial extracellular solute-binding protein
DGMANHCO_00260 3.4e-31
DGMANHCO_00261 1.2e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
DGMANHCO_00262 1.7e-145 S Alpha/beta hydrolase of unknown function (DUF915)
DGMANHCO_00263 7e-164 cylA V ABC transporter
DGMANHCO_00264 1.2e-147 cylB V ABC-2 type transporter
DGMANHCO_00265 1.7e-73 K LytTr DNA-binding domain
DGMANHCO_00266 9.6e-44 S Protein of unknown function (DUF3021)
DGMANHCO_00267 0.0 yjcE P Sodium proton antiporter
DGMANHCO_00268 2.1e-241 S Protein of unknown function (DUF3800)
DGMANHCO_00269 4.8e-249 yifK E Amino acid permease
DGMANHCO_00270 1.7e-156 yeaE S Aldo/keto reductase family
DGMANHCO_00271 5.1e-113 ylbE GM NAD(P)H-binding
DGMANHCO_00272 1.9e-278 lsa S ABC transporter
DGMANHCO_00273 1.6e-76 O OsmC-like protein
DGMANHCO_00274 3e-67
DGMANHCO_00275 4.6e-31 K 'Cold-shock' DNA-binding domain
DGMANHCO_00276 4.6e-252 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DGMANHCO_00277 3e-173 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
DGMANHCO_00278 5.6e-267 yfnA E Amino Acid
DGMANHCO_00279 3.6e-217 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DGMANHCO_00280 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DGMANHCO_00281 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
DGMANHCO_00282 7.7e-129 treR K UTRA
DGMANHCO_00283 6e-222 oxlT P Major Facilitator Superfamily
DGMANHCO_00284 0.0 V ABC transporter
DGMANHCO_00285 0.0 XK27_09600 V ABC transporter, ATP-binding protein
DGMANHCO_00286 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DGMANHCO_00287 1.6e-165 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
DGMANHCO_00288 1.5e-86 yjdB S Domain of unknown function (DUF4767)
DGMANHCO_00289 1e-48 lciIC K Helix-turn-helix XRE-family like proteins
DGMANHCO_00292 2.8e-129 repA K DeoR C terminal sensor domain
DGMANHCO_00294 3.4e-135 zmp3 O Zinc-dependent metalloprotease
DGMANHCO_00295 2.2e-253 lytN 3.5.1.104 M LysM domain
DGMANHCO_00296 1.4e-15 2.7.1.39 S Phosphotransferase enzyme family
DGMANHCO_00297 4.6e-67 S Iron-sulphur cluster biosynthesis
DGMANHCO_00299 3.1e-215 V ABC transporter transmembrane region
DGMANHCO_00300 2.9e-88 V ABC transporter transmembrane region
DGMANHCO_00301 2.4e-131 V ABC transporter transmembrane region
DGMANHCO_00302 2.1e-36
DGMANHCO_00303 4.6e-52 K Transcriptional
DGMANHCO_00304 1.6e-128 hchA S DJ-1/PfpI family
DGMANHCO_00305 6.9e-290 E Bacterial extracellular solute-binding proteins, family 5 Middle
DGMANHCO_00306 4.2e-167 oppB P Binding-protein-dependent transport system inner membrane component
DGMANHCO_00307 7.4e-175 amiD EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
DGMANHCO_00308 8.5e-24
DGMANHCO_00309 9.6e-200 oppD P Oligopeptide/dipeptide transporter, C-terminal region
DGMANHCO_00310 7.4e-158 oppF P Oligopeptide/dipeptide transporter, C-terminal region
DGMANHCO_00311 6.7e-96 ydaF J Acetyltransferase (GNAT) domain
DGMANHCO_00312 1.1e-87 V ATPases associated with a variety of cellular activities
DGMANHCO_00313 2.6e-141
DGMANHCO_00314 6.7e-19
DGMANHCO_00315 1.1e-124 skfE V ATPases associated with a variety of cellular activities
DGMANHCO_00316 1.2e-59 yvoA_1 K Transcriptional regulator, GntR family
DGMANHCO_00317 1.3e-159 S Alpha beta hydrolase
DGMANHCO_00318 9.5e-181 K Helix-turn-helix XRE-family like proteins
DGMANHCO_00319 6.2e-126 S membrane transporter protein
DGMANHCO_00320 4.1e-259 EGP Major facilitator Superfamily
DGMANHCO_00321 9.6e-115 K Transcriptional regulator
DGMANHCO_00322 2.9e-293 M Exporter of polyketide antibiotics
DGMANHCO_00323 2.6e-169 yjjC V ABC transporter
DGMANHCO_00324 7.9e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DGMANHCO_00325 5.7e-61 yeaO S Protein of unknown function, DUF488
DGMANHCO_00326 1.3e-173 corA P CorA-like Mg2+ transporter protein
DGMANHCO_00327 1.6e-151 S AAA-like domain
DGMANHCO_00328 9.8e-49 S SIR2-like domain
DGMANHCO_00329 6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DGMANHCO_00330 3e-178 coaA 2.7.1.33 F Pantothenic acid kinase
DGMANHCO_00331 3.9e-12
DGMANHCO_00332 8.7e-23
DGMANHCO_00333 1.4e-275 pipD E Dipeptidase
DGMANHCO_00334 8.5e-84 ykhA 3.1.2.20 I Thioesterase superfamily
DGMANHCO_00335 0.0 helD 3.6.4.12 L DNA helicase
DGMANHCO_00336 7.1e-21
DGMANHCO_00337 0.0 yjbQ P TrkA C-terminal domain protein
DGMANHCO_00338 1.1e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
DGMANHCO_00339 8e-79 yjhE S Phage tail protein
DGMANHCO_00340 4.1e-240 mntH P H( )-stimulated, divalent metal cation uptake system
DGMANHCO_00341 4.4e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
DGMANHCO_00342 2.3e-127 pgm3 G Phosphoglycerate mutase family
DGMANHCO_00343 0.0 V FtsX-like permease family
DGMANHCO_00344 2.6e-135 cysA V ABC transporter, ATP-binding protein
DGMANHCO_00345 0.0 E amino acid
DGMANHCO_00346 3.4e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
DGMANHCO_00347 2.4e-237 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DGMANHCO_00348 9e-152 nodB3 G Polysaccharide deacetylase
DGMANHCO_00349 2.9e-274 S Glucosyl transferase GtrII
DGMANHCO_00350 8e-223
DGMANHCO_00351 1.3e-93
DGMANHCO_00352 3.4e-173 3.1.4.46 M Peptidase_C39 like family
DGMANHCO_00353 2.1e-85 ykuL S CBS domain
DGMANHCO_00354 2.5e-135 gla U Major intrinsic protein
DGMANHCO_00355 2.5e-97 S Phosphoesterase
DGMANHCO_00356 3.8e-276 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DGMANHCO_00357 8.8e-84 yslB S Protein of unknown function (DUF2507)
DGMANHCO_00358 1.5e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DGMANHCO_00359 1.2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DGMANHCO_00360 2.6e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
DGMANHCO_00361 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DGMANHCO_00362 6.1e-20 dltX S D-Ala-teichoic acid biosynthesis protein
DGMANHCO_00363 6.6e-53 trxA O Belongs to the thioredoxin family
DGMANHCO_00364 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DGMANHCO_00365 9.6e-92 cvpA S Colicin V production protein
DGMANHCO_00366 5.8e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DGMANHCO_00367 6.8e-53 yrzB S Belongs to the UPF0473 family
DGMANHCO_00368 1.6e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DGMANHCO_00369 4e-43 yrzL S Belongs to the UPF0297 family
DGMANHCO_00371 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DGMANHCO_00372 7.8e-174
DGMANHCO_00373 4.3e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DGMANHCO_00374 3.7e-179 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
DGMANHCO_00375 2.3e-240 ytoI K DRTGG domain
DGMANHCO_00376 1.2e-205 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DGMANHCO_00377 3.3e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DGMANHCO_00378 2.3e-116 sirR K Helix-turn-helix diphteria tox regulatory element
DGMANHCO_00379 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DGMANHCO_00380 1.2e-65 yajC U Preprotein translocase
DGMANHCO_00381 2.3e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DGMANHCO_00382 2.1e-207 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DGMANHCO_00383 6.7e-64 gntP EG Gluconate
DGMANHCO_00384 1.9e-305 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
DGMANHCO_00385 1.2e-168 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
DGMANHCO_00386 2.5e-123 gntR K rpiR family
DGMANHCO_00387 1e-164 yvgN C Aldo keto reductase
DGMANHCO_00388 1.8e-141 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
DGMANHCO_00389 3.6e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DGMANHCO_00390 8.6e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DGMANHCO_00391 1.8e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DGMANHCO_00392 3.9e-218 hpk31 2.7.13.3 T Histidine kinase
DGMANHCO_00393 1.9e-121 K response regulator
DGMANHCO_00394 4.7e-120
DGMANHCO_00395 2.5e-275 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DGMANHCO_00396 3e-105 XK27_01040 S Protein of unknown function (DUF1129)
DGMANHCO_00397 1.3e-185 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DGMANHCO_00398 1.8e-29 yyzM S Bacterial protein of unknown function (DUF951)
DGMANHCO_00399 5.2e-156 spo0J K Belongs to the ParB family
DGMANHCO_00400 9.7e-138 soj D Sporulation initiation inhibitor
DGMANHCO_00401 4e-137 noc K Belongs to the ParB family
DGMANHCO_00402 4.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DGMANHCO_00403 1.3e-66
DGMANHCO_00404 3e-127 cobQ S glutamine amidotransferase
DGMANHCO_00405 6.5e-108 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
DGMANHCO_00406 2.5e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DGMANHCO_00407 3.7e-152 S Protein of unknown function (DUF979)
DGMANHCO_00408 3.3e-113 S Protein of unknown function (DUF969)
DGMANHCO_00410 1.6e-62 asp2 S Asp23 family, cell envelope-related function
DGMANHCO_00411 7.4e-68 asp23 S Asp23 family, cell envelope-related function
DGMANHCO_00412 2.8e-25
DGMANHCO_00413 5.3e-82 S Protein conserved in bacteria
DGMANHCO_00414 9.9e-39 S Transglycosylase associated protein
DGMANHCO_00415 1.4e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
DGMANHCO_00416 1.9e-170 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DGMANHCO_00417 1.1e-26
DGMANHCO_00418 1.2e-36
DGMANHCO_00419 2.4e-83 fld C Flavodoxin
DGMANHCO_00420 2.8e-48
DGMANHCO_00421 6.5e-90
DGMANHCO_00423 1.6e-134 Q Methyltransferase domain
DGMANHCO_00424 1.6e-293 S ABC transporter
DGMANHCO_00425 6e-174 draG O ADP-ribosylglycohydrolase
DGMANHCO_00426 2.4e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DGMANHCO_00427 1.4e-40
DGMANHCO_00428 3.3e-135 XK27_06755 S Protein of unknown function (DUF975)
DGMANHCO_00429 2e-146 M Glycosyltransferase like family 2
DGMANHCO_00430 2.4e-133 glcR K DeoR C terminal sensor domain
DGMANHCO_00431 7e-71 T Sh3 type 3 domain protein
DGMANHCO_00432 2.9e-249 brnQ U Component of the transport system for branched-chain amino acids
DGMANHCO_00433 7.4e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DGMANHCO_00434 0.0 pepF E oligoendopeptidase F
DGMANHCO_00435 7.1e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
DGMANHCO_00436 4.2e-166 T Calcineurin-like phosphoesterase superfamily domain
DGMANHCO_00437 3.3e-133 znuB U ABC 3 transport family
DGMANHCO_00438 2.2e-128 fhuC 3.6.3.35 P ABC transporter
DGMANHCO_00439 7.6e-58
DGMANHCO_00440 1.1e-197 S Protein conserved in bacteria
DGMANHCO_00441 1.4e-161 S Glycosyltransferase like family 2
DGMANHCO_00442 5.4e-259 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
DGMANHCO_00443 0.0 M Glycosyl hydrolases family 25
DGMANHCO_00444 3.9e-147 M Glycosyltransferase sugar-binding region containing DXD motif
DGMANHCO_00445 8.8e-159 S Glycosyltransferase like family 2
DGMANHCO_00446 8e-115 welB S Glycosyltransferase like family 2
DGMANHCO_00447 1.2e-151 S Glycosyl transferase family 2
DGMANHCO_00448 2.4e-248 S O-antigen ligase like membrane protein
DGMANHCO_00449 9.3e-139 gntP EG Gluconate
DGMANHCO_00450 5.4e-53 trxC O Belongs to the thioredoxin family
DGMANHCO_00451 6.3e-137 thrE S Putative threonine/serine exporter
DGMANHCO_00452 1.4e-75 S Threonine/Serine exporter, ThrE
DGMANHCO_00453 1.4e-35 livJ E Receptor family ligand binding region
DGMANHCO_00454 7.3e-141 livJ E Receptor family ligand binding region
DGMANHCO_00455 6.9e-148 livH U Branched-chain amino acid transport system / permease component
DGMANHCO_00456 4.6e-121 livM E Branched-chain amino acid transport system / permease component
DGMANHCO_00457 8.1e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
DGMANHCO_00458 1.2e-11 livF E ABC transporter
DGMANHCO_00459 2.3e-69 livF E ABC transporter
DGMANHCO_00460 3.9e-67 ydeA S DJ-1/PfpI family
DGMANHCO_00461 1.1e-22 mutT 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
DGMANHCO_00462 1.2e-39 yvdC S MazG nucleotide pyrophosphohydrolase domain
DGMANHCO_00463 3.1e-167 S Alpha/beta hydrolase of unknown function (DUF915)
DGMANHCO_00464 4.2e-234 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DGMANHCO_00465 7.6e-118 XK27_12570 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DGMANHCO_00466 8.2e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DGMANHCO_00467 6.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
DGMANHCO_00468 3.4e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
DGMANHCO_00469 3.6e-152 M NlpC P60 family protein
DGMANHCO_00472 1.4e-259 nox 1.6.3.4 C NADH oxidase
DGMANHCO_00473 2.9e-89 sepS16B
DGMANHCO_00474 8.1e-120
DGMANHCO_00475 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
DGMANHCO_00476 6e-241 G Bacterial extracellular solute-binding protein
DGMANHCO_00477 6e-86
DGMANHCO_00478 0.0 strH 3.2.1.52 GH20 G Gram-positive signal peptide protein, YSIRK family
DGMANHCO_00479 4.3e-194 manA 5.3.1.8 G mannose-6-phosphate isomerase
DGMANHCO_00480 7.6e-177 sitA P Belongs to the bacterial solute-binding protein 9 family
DGMANHCO_00481 3.6e-144 mtsB U ABC 3 transport family
DGMANHCO_00482 2.2e-131 mntB 3.6.3.35 P AAA domain, putative AbiEii toxin, Type IV TA system
DGMANHCO_00483 1.1e-275 aldA 1.2.1.21, 1.2.1.22 C Belongs to the aldehyde dehydrogenase family
DGMANHCO_00484 3e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DGMANHCO_00485 5.9e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
DGMANHCO_00486 1.6e-117 GM NmrA-like family
DGMANHCO_00487 8.3e-111 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
DGMANHCO_00488 2.6e-70
DGMANHCO_00489 2.4e-253 M domain protein
DGMANHCO_00490 5.4e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
DGMANHCO_00491 6.1e-20
DGMANHCO_00492 3e-60
DGMANHCO_00495 1.9e-51 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DGMANHCO_00496 8.7e-69 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DGMANHCO_00498 2.3e-157 phnD P Phosphonate ABC transporter
DGMANHCO_00499 7.5e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DGMANHCO_00500 1.7e-134 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
DGMANHCO_00501 1.3e-145 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
DGMANHCO_00502 1.8e-173 ssuA P NMT1-like family
DGMANHCO_00503 6.8e-292 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
DGMANHCO_00504 1.1e-167 yfiQ I Acyltransferase family
DGMANHCO_00505 1.2e-115 ssuB P ATPases associated with a variety of cellular activities
DGMANHCO_00506 1.2e-61 ssuC U Binding-protein-dependent transport system inner membrane component
DGMANHCO_00507 4.9e-66 ssuC U Binding-protein-dependent transport system inner membrane component
DGMANHCO_00508 1.2e-121 S ABC-2 family transporter protein
DGMANHCO_00509 3.2e-55
DGMANHCO_00510 2.3e-53
DGMANHCO_00511 3.3e-141 recO L Involved in DNA repair and RecF pathway recombination
DGMANHCO_00512 9.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DGMANHCO_00513 8e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
DGMANHCO_00514 3.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
DGMANHCO_00515 2e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DGMANHCO_00516 2.9e-179 phoH T phosphate starvation-inducible protein PhoH
DGMANHCO_00518 6.1e-68 yqeY S YqeY-like protein
DGMANHCO_00519 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DGMANHCO_00520 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DGMANHCO_00521 1.3e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DGMANHCO_00522 7.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DGMANHCO_00523 2.6e-82 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
DGMANHCO_00524 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DGMANHCO_00525 2.6e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
DGMANHCO_00526 1.7e-35 XK27_04345 3.6.1.1 C Inorganic pyrophosphatase
DGMANHCO_00527 4.1e-167 1.6.5.5 C nadph quinone reductase
DGMANHCO_00528 2.1e-76
DGMANHCO_00529 8.4e-131 K Helix-turn-helix
DGMANHCO_00530 5.8e-280
DGMANHCO_00531 6.9e-156 V ABC transporter
DGMANHCO_00532 2.5e-73 FG adenosine 5'-monophosphoramidase activity
DGMANHCO_00533 5.9e-244 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
DGMANHCO_00534 2.6e-117 3.1.3.18 J HAD-hyrolase-like
DGMANHCO_00535 1.2e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DGMANHCO_00536 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DGMANHCO_00537 1.3e-43
DGMANHCO_00538 5.9e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DGMANHCO_00539 1.1e-172 prmA J Ribosomal protein L11 methyltransferase
DGMANHCO_00540 2.9e-87 XK27_03960 S Protein of unknown function (DUF3013)
DGMANHCO_00541 6.2e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
DGMANHCO_00542 5.3e-37
DGMANHCO_00543 3.8e-66 S Protein of unknown function (DUF1093)
DGMANHCO_00544 8.2e-19
DGMANHCO_00545 1.2e-48
DGMANHCO_00546 1.3e-44 XK27_02675 K Acetyltransferase (GNAT) domain
DGMANHCO_00547 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DGMANHCO_00548 6.8e-69 2.7.1.191 G PTS system fructose IIA component
DGMANHCO_00549 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
DGMANHCO_00550 2.4e-153 G PTS system mannose/fructose/sorbose family IID component
DGMANHCO_00551 2.8e-127 G PTS system sorbose-specific iic component
DGMANHCO_00552 3e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
DGMANHCO_00553 3.1e-184 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
DGMANHCO_00554 1.9e-43 S Bacterial toxin of type II toxin-antitoxin system, YafQ
DGMANHCO_00555 1.7e-151 S hydrolase
DGMANHCO_00556 1e-262 npr 1.11.1.1 C NADH oxidase
DGMANHCO_00557 5.3e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
DGMANHCO_00558 1.5e-184 hrtB V ABC transporter permease
DGMANHCO_00559 1.6e-85 ygfC K Bacterial regulatory proteins, tetR family
DGMANHCO_00560 3.8e-113 3.2.1.17 M hydrolase, family 25
DGMANHCO_00561 8.1e-12 S YvrJ protein family
DGMANHCO_00563 1.4e-237 kgtP EGP Sugar (and other) transporter
DGMANHCO_00564 1.6e-115 P Binding-protein-dependent transport system inner membrane component
DGMANHCO_00565 2.9e-114 P Binding-protein-dependent transport system inner membrane component
DGMANHCO_00566 5.1e-159 ET Bacterial periplasmic substrate-binding proteins
DGMANHCO_00567 1.4e-128 E ABC transporter
DGMANHCO_00568 4.6e-191 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
DGMANHCO_00569 2.9e-218 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
DGMANHCO_00570 0.0 mtlF 2.7.1.197 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DGMANHCO_00571 6.7e-96 hxlB 4.1.2.43, 5.3.1.27 M SIS domain
DGMANHCO_00572 7.7e-112 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
DGMANHCO_00573 1.3e-134 fruR K DeoR C terminal sensor domain
DGMANHCO_00574 1.4e-121 S Haloacid dehalogenase-like hydrolase
DGMANHCO_00576 2.7e-19 M Bacterial Ig-like domain (group 3)
DGMANHCO_00577 2.5e-200 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
DGMANHCO_00578 1.1e-225 amd 3.5.1.47 E Peptidase family M20/M25/M40
DGMANHCO_00579 3.8e-79 S Threonine/Serine exporter, ThrE
DGMANHCO_00580 2.2e-134 thrE S Putative threonine/serine exporter
DGMANHCO_00582 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DGMANHCO_00583 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DGMANHCO_00585 8.2e-129 jag S R3H domain protein
DGMANHCO_00586 2.6e-136 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DGMANHCO_00587 6.1e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DGMANHCO_00588 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DGMANHCO_00589 1.2e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DGMANHCO_00590 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DGMANHCO_00591 1.7e-31 yaaA S S4 domain protein YaaA
DGMANHCO_00592 1.2e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DGMANHCO_00593 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DGMANHCO_00594 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DGMANHCO_00595 1.5e-124 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DGMANHCO_00596 8.5e-75 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DGMANHCO_00597 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
DGMANHCO_00598 3.9e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DGMANHCO_00599 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DGMANHCO_00600 4.7e-282 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
DGMANHCO_00601 3.9e-179 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
DGMANHCO_00602 2.4e-13
DGMANHCO_00603 4.9e-43 O Belongs to the peptidase S8 family
DGMANHCO_00604 1.5e-143 O Belongs to the peptidase S8 family
DGMANHCO_00605 0.0 O Belongs to the peptidase S8 family
DGMANHCO_00606 0.0 pepN 3.4.11.2 E aminopeptidase
DGMANHCO_00607 7.1e-275 ycaM E amino acid
DGMANHCO_00608 5.3e-76 S Protein of unknown function (DUF1440)
DGMANHCO_00609 4.8e-165 K Transcriptional regulator, LysR family
DGMANHCO_00610 3e-159 G Xylose isomerase-like TIM barrel
DGMANHCO_00611 1.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
DGMANHCO_00612 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DGMANHCO_00613 2.9e-213 ydiN EGP Major Facilitator Superfamily
DGMANHCO_00614 2.1e-168 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DGMANHCO_00615 4.4e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
DGMANHCO_00616 4.6e-174 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DGMANHCO_00617 5.8e-28
DGMANHCO_00619 6.7e-223 L Belongs to the 'phage' integrase family
DGMANHCO_00620 2.2e-09
DGMANHCO_00622 1.1e-62 yugI 5.3.1.9 J general stress protein
DGMANHCO_00623 2.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DGMANHCO_00624 7.9e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
DGMANHCO_00625 6.7e-87 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
DGMANHCO_00626 5.2e-116 dedA S SNARE-like domain protein
DGMANHCO_00627 1.1e-112 S Protein of unknown function (DUF1461)
DGMANHCO_00628 2.8e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DGMANHCO_00629 6e-117 yutD S Protein of unknown function (DUF1027)
DGMANHCO_00630 2.8e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
DGMANHCO_00631 1.8e-115 S Calcineurin-like phosphoesterase
DGMANHCO_00632 1.4e-114 yibF S overlaps another CDS with the same product name
DGMANHCO_00633 9.8e-189 yibE S overlaps another CDS with the same product name
DGMANHCO_00634 6.1e-54
DGMANHCO_00635 1.1e-258 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DGMANHCO_00636 3.8e-273 pepV 3.5.1.18 E dipeptidase PepV
DGMANHCO_00637 9.5e-138 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DGMANHCO_00638 1.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
DGMANHCO_00639 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
DGMANHCO_00640 5.1e-179 ccpA K catabolite control protein A
DGMANHCO_00641 6.3e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DGMANHCO_00642 3e-90 niaR S 3H domain
DGMANHCO_00643 2.7e-86 ytxH S YtxH-like protein
DGMANHCO_00644 6e-12 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DGMANHCO_00645 2.1e-152 ykuT M mechanosensitive ion channel
DGMANHCO_00646 3.5e-155 XK27_00890 S Domain of unknown function (DUF368)
DGMANHCO_00647 5.9e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DGMANHCO_00648 1.3e-88 S ECF-type riboflavin transporter, S component
DGMANHCO_00649 2.9e-145 CcmA5 V ABC transporter
DGMANHCO_00650 0.0
DGMANHCO_00651 4.6e-177 yicL EG EamA-like transporter family
DGMANHCO_00652 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
DGMANHCO_00653 5.1e-101 N WxL domain surface cell wall-binding
DGMANHCO_00654 1.8e-57
DGMANHCO_00655 1.1e-111 S WxL domain surface cell wall-binding
DGMANHCO_00656 4.4e-198 XK27_00720 S Leucine-rich repeat (LRR) protein
DGMANHCO_00657 1.5e-38
DGMANHCO_00658 4e-171 S Cell surface protein
DGMANHCO_00659 2.2e-117 S WxL domain surface cell wall-binding
DGMANHCO_00660 4.8e-252 brnQ U Component of the transport system for branched-chain amino acids
DGMANHCO_00661 7.2e-31
DGMANHCO_00662 5.3e-122 tcyB E ABC transporter
DGMANHCO_00663 3.9e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
DGMANHCO_00664 5.1e-212 metC 4.4.1.8 E cystathionine
DGMANHCO_00665 7.3e-183 CP_0155 3.5.1.28 M Glycosyl hydrolases family 25
DGMANHCO_00666 1.2e-152 licT K CAT RNA binding domain
DGMANHCO_00667 2e-289 cydC V ABC transporter transmembrane region
DGMANHCO_00668 6.5e-87 cydD CO ABC transporter transmembrane region
DGMANHCO_00669 1.5e-217 cydD CO ABC transporter transmembrane region
DGMANHCO_00670 1.2e-73 S NusG domain II
DGMANHCO_00671 1e-156 M Peptidoglycan-binding domain 1 protein
DGMANHCO_00672 4.3e-141
DGMANHCO_00673 1.5e-214 ywhK S Membrane
DGMANHCO_00674 7.1e-62 S Protein of unknown function (DUF1093)
DGMANHCO_00675 7.1e-50 yvlA
DGMANHCO_00676 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DGMANHCO_00677 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DGMANHCO_00678 1.3e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
DGMANHCO_00679 6.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
DGMANHCO_00681 3.1e-237 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
DGMANHCO_00682 1.4e-189 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DGMANHCO_00683 8.6e-40
DGMANHCO_00684 1.4e-86
DGMANHCO_00685 8e-24
DGMANHCO_00686 5e-165 yicL EG EamA-like transporter family
DGMANHCO_00687 3.3e-112 tag 3.2.2.20 L glycosylase
DGMANHCO_00688 5e-78 usp5 T universal stress protein
DGMANHCO_00689 5.4e-192 S Protein of unknown function C-terminal (DUF3324)
DGMANHCO_00690 1.2e-87
DGMANHCO_00691 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DGMANHCO_00692 1.3e-116 sodA 1.15.1.1 C Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DGMANHCO_00693 1.3e-157 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DGMANHCO_00694 8.9e-158 I alpha/beta hydrolase fold
DGMANHCO_00695 1.6e-28
DGMANHCO_00696 9.3e-74
DGMANHCO_00697 6.8e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DGMANHCO_00698 1.1e-124 citR K FCD
DGMANHCO_00699 3.4e-266 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
DGMANHCO_00700 6.9e-93 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
DGMANHCO_00701 5.9e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
DGMANHCO_00702 9e-156 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
DGMANHCO_00703 1.3e-48 citD C Covalent carrier of the coenzyme of citrate lyase
DGMANHCO_00704 1e-179 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DGMANHCO_00706 1.8e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
DGMANHCO_00707 6.2e-40 gcdC 2.3.1.12 I Biotin-requiring enzyme
DGMANHCO_00708 1.2e-52
DGMANHCO_00709 4.8e-241 citM C Citrate transporter
DGMANHCO_00710 2.8e-41
DGMANHCO_00711 5.1e-104 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DGMANHCO_00712 1.6e-88 K GNAT family
DGMANHCO_00713 1.2e-106 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
DGMANHCO_00714 9.7e-58 K Transcriptional regulator PadR-like family
DGMANHCO_00715 1.2e-88 ORF00048
DGMANHCO_00716 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DGMANHCO_00717 8.6e-28 M Leucine rich repeats (6 copies)
DGMANHCO_00718 0.0 M Leucine rich repeats (6 copies)
DGMANHCO_00719 7.5e-206 bacI V MacB-like periplasmic core domain
DGMANHCO_00720 7.1e-124 V ABC transporter
DGMANHCO_00721 1.8e-151 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DGMANHCO_00722 5.2e-10
DGMANHCO_00723 3.1e-43
DGMANHCO_00724 3.3e-149 S haloacid dehalogenase-like hydrolase
DGMANHCO_00725 3.4e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DGMANHCO_00726 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
DGMANHCO_00727 0.0 mtlR K Mga helix-turn-helix domain
DGMANHCO_00728 1.1e-77 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DGMANHCO_00729 5.6e-206 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
DGMANHCO_00730 2.4e-186 lipA I Carboxylesterase family
DGMANHCO_00731 6.6e-181 D Alpha beta
DGMANHCO_00732 3e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DGMANHCO_00733 3.6e-48 K Helix-turn-helix domain
DGMANHCO_00734 8.5e-265 L Exonuclease
DGMANHCO_00735 7.1e-53
DGMANHCO_00737 1.1e-74 ohr O OsmC-like protein
DGMANHCO_00738 1.4e-189 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
DGMANHCO_00739 5e-102 dhaL 2.7.1.121 S Dak2
DGMANHCO_00740 7.3e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
DGMANHCO_00741 1.5e-100 K Bacterial regulatory proteins, tetR family
DGMANHCO_00742 1.7e-15
DGMANHCO_00743 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
DGMANHCO_00744 7.9e-84
DGMANHCO_00745 1.3e-198 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
DGMANHCO_00746 2.6e-155 metQ_4 P Belongs to the nlpA lipoprotein family
DGMANHCO_00747 0.0 pip V domain protein
DGMANHCO_00749 1.6e-302 yfiB V ABC transporter transmembrane region
DGMANHCO_00750 7.5e-311 md2 V ABC transporter
DGMANHCO_00751 9.4e-12 XK27_02675 K Acetyltransferase (GNAT) domain
DGMANHCO_00753 1.5e-109 1.6.5.2 S Flavodoxin-like fold
DGMANHCO_00754 1e-97 K Bacterial regulatory proteins, tetR family
DGMANHCO_00755 3.2e-144 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
DGMANHCO_00756 3.6e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
DGMANHCO_00757 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DGMANHCO_00758 5.3e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DGMANHCO_00759 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
DGMANHCO_00760 1.8e-57
DGMANHCO_00761 1.4e-81 6.3.3.2 S ASCH
DGMANHCO_00762 1.8e-23
DGMANHCO_00763 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DGMANHCO_00764 1.9e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DGMANHCO_00765 4.4e-309 dnaK O Heat shock 70 kDa protein
DGMANHCO_00766 3.4e-98 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DGMANHCO_00767 4.2e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DGMANHCO_00768 5.3e-225 hemN H Involved in the biosynthesis of porphyrin-containing compound
DGMANHCO_00769 3.1e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DGMANHCO_00770 4.4e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DGMANHCO_00771 1e-142 terC P Integral membrane protein TerC family
DGMANHCO_00772 3.2e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DGMANHCO_00773 6e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DGMANHCO_00774 1.4e-104 yjbF S SNARE associated Golgi protein
DGMANHCO_00775 2.2e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DGMANHCO_00776 1.6e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
DGMANHCO_00778 3.5e-74 S Protein of unknown function (DUF3290)
DGMANHCO_00779 6.6e-119 yviA S Protein of unknown function (DUF421)
DGMANHCO_00780 2e-144 S Alpha beta hydrolase
DGMANHCO_00781 1.7e-155
DGMANHCO_00782 1.3e-156 dkgB S reductase
DGMANHCO_00783 2.5e-83 nrdI F Belongs to the NrdI family
DGMANHCO_00784 5.2e-178 D Alpha beta
DGMANHCO_00785 3.3e-77 K Transcriptional regulator
DGMANHCO_00786 8.5e-122 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
DGMANHCO_00787 8.7e-199 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DGMANHCO_00788 2.6e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DGMANHCO_00789 2.6e-45
DGMANHCO_00790 1.9e-180 3.4.11.5 I carboxylic ester hydrolase activity
DGMANHCO_00791 0.0 yfgQ P E1-E2 ATPase
DGMANHCO_00792 1.9e-80 ndk 2.7.4.6 F Belongs to the NDK family
DGMANHCO_00793 4.4e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DGMANHCO_00794 3.7e-94 V ABC transporter, ATP-binding protein
DGMANHCO_00795 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DGMANHCO_00796 9e-75 rplI J Binds to the 23S rRNA
DGMANHCO_00797 4.6e-247 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DGMANHCO_00798 5.4e-217
DGMANHCO_00799 1.1e-273 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DGMANHCO_00800 7.6e-129 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DGMANHCO_00801 1.8e-119 K Helix-turn-helix domain, rpiR family
DGMANHCO_00802 2.4e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DGMANHCO_00803 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
DGMANHCO_00804 1.1e-56 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
DGMANHCO_00805 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
DGMANHCO_00806 2.3e-159 lysR5 K LysR substrate binding domain
DGMANHCO_00807 4e-167 gbuC E glycine betaine
DGMANHCO_00808 2e-131 proW E glycine betaine
DGMANHCO_00809 4.5e-222 gbuA 3.6.3.32 E glycine betaine
DGMANHCO_00810 9.2e-138 sfsA S Belongs to the SfsA family
DGMANHCO_00811 1.8e-67 usp1 T Universal stress protein family
DGMANHCO_00812 7.4e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
DGMANHCO_00814 2.4e-130 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DGMANHCO_00815 3.2e-286 thrC 4.2.3.1 E Threonine synthase
DGMANHCO_00816 6.4e-229 hom 1.1.1.3 E homoserine dehydrogenase
DGMANHCO_00817 1.1e-250 yclM 2.7.2.4 E Belongs to the aspartokinase family
DGMANHCO_00818 1.1e-166 yqiK S SPFH domain / Band 7 family
DGMANHCO_00819 2.3e-39
DGMANHCO_00820 2.5e-173 pfoS S Phosphotransferase system, EIIC
DGMANHCO_00821 8e-177 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DGMANHCO_00822 7.1e-217 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
DGMANHCO_00823 2.5e-47
DGMANHCO_00824 1e-55 ywjH S Protein of unknown function (DUF1634)
DGMANHCO_00825 4.6e-125 yxaA S Sulfite exporter TauE/SafE
DGMANHCO_00826 5.6e-218 S TPM domain
DGMANHCO_00827 1.7e-116
DGMANHCO_00828 7.2e-261 nox 1.6.3.4 C NADH oxidase
DGMANHCO_00829 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
DGMANHCO_00830 1.4e-111 gadR K Helix-turn-helix XRE-family like proteins
DGMANHCO_00831 1.9e-225 V ABC transporter transmembrane region
DGMANHCO_00832 1.2e-213 S nuclear-transcribed mRNA catabolic process, no-go decay
DGMANHCO_00833 6.4e-76 S NUDIX domain
DGMANHCO_00834 1.1e-43
DGMANHCO_00835 1.5e-89 V ATPases associated with a variety of cellular activities
DGMANHCO_00836 1.3e-67
DGMANHCO_00837 3e-53
DGMANHCO_00838 4.1e-83
DGMANHCO_00839 1.4e-298 oppA E ABC transporter, substratebinding protein
DGMANHCO_00840 1.6e-152 V ABC-type multidrug transport system, ATPase and permease components
DGMANHCO_00841 7.7e-46 EGP Major facilitator Superfamily
DGMANHCO_00842 3.1e-179 EGP Major facilitator Superfamily
DGMANHCO_00843 1.6e-49 K TRANSCRIPTIONal
DGMANHCO_00844 0.0 ydgH S MMPL family
DGMANHCO_00845 7.4e-109 K Tetracycline repressor, C-terminal all-alpha domain
DGMANHCO_00847 3.3e-110 opuCD P Binding-protein-dependent transport system inner membrane component
DGMANHCO_00848 3.3e-172 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DGMANHCO_00849 1e-105 opuCB E ABC transporter permease
DGMANHCO_00850 7.2e-215 opuCA 2.7.7.7 E ABC transporter, ATP-binding protein
DGMANHCO_00851 6.7e-23 ypbD S CAAX protease self-immunity
DGMANHCO_00852 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
DGMANHCO_00853 5.6e-33 copZ P Heavy-metal-associated domain
DGMANHCO_00854 1.5e-98 dps P Belongs to the Dps family
DGMANHCO_00855 6.8e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
DGMANHCO_00856 2e-171 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DGMANHCO_00857 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DGMANHCO_00858 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DGMANHCO_00859 3.4e-188 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DGMANHCO_00860 3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
DGMANHCO_00861 6e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DGMANHCO_00862 3.5e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
DGMANHCO_00863 8.2e-60 yitW S Iron-sulfur cluster assembly protein
DGMANHCO_00864 1.1e-141
DGMANHCO_00865 9.4e-175
DGMANHCO_00866 2.6e-263 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
DGMANHCO_00867 1.1e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DGMANHCO_00868 1.3e-179 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
DGMANHCO_00869 1.4e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
DGMANHCO_00870 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DGMANHCO_00871 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DGMANHCO_00872 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DGMANHCO_00873 1.4e-11 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DGMANHCO_00874 7.1e-86 ypmB S Protein conserved in bacteria
DGMANHCO_00875 2.2e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
DGMANHCO_00876 3.2e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
DGMANHCO_00877 6.7e-113 dnaD L DnaD domain protein
DGMANHCO_00878 3e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DGMANHCO_00879 4.4e-85 comEB 3.5.4.12 F ComE operon protein 2
DGMANHCO_00880 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
DGMANHCO_00881 5.1e-121 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DGMANHCO_00882 1.3e-107 ypsA S Belongs to the UPF0398 family
DGMANHCO_00883 2.3e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DGMANHCO_00884 8.2e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DGMANHCO_00885 1e-173 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DGMANHCO_00886 1.9e-33
DGMANHCO_00887 9.6e-194 lplA 6.3.1.20 H Lipoate-protein ligase
DGMANHCO_00888 0.0 pepO 3.4.24.71 O Peptidase family M13
DGMANHCO_00889 7.1e-161 K Transcriptional regulator
DGMANHCO_00890 2.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DGMANHCO_00891 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DGMANHCO_00892 2e-38 nrdH O Glutaredoxin
DGMANHCO_00893 9.3e-275 S Mga helix-turn-helix domain
DGMANHCO_00894 1.4e-48
DGMANHCO_00895 2.6e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGMANHCO_00896 1.9e-109 XK27_02070 S Nitroreductase family
DGMANHCO_00897 6.5e-69 rnhA 3.1.26.4 L Ribonuclease HI
DGMANHCO_00898 1.3e-45 S Family of unknown function (DUF5322)
DGMANHCO_00899 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DGMANHCO_00900 2.1e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DGMANHCO_00901 5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DGMANHCO_00902 1.7e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DGMANHCO_00903 5.9e-236 pyrP F Permease
DGMANHCO_00904 1.6e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DGMANHCO_00905 2.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DGMANHCO_00906 1.5e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DGMANHCO_00907 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
DGMANHCO_00908 6.9e-156 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DGMANHCO_00909 1.4e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DGMANHCO_00910 8.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DGMANHCO_00911 5.1e-148 pta 2.3.1.19, 2.3.1.8 C Phosphate acetyl/butaryl transferase
DGMANHCO_00912 2.4e-201 buk 2.7.2.7 C Acetokinase family
DGMANHCO_00913 1.4e-259 lpdA 1.8.1.4 C 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
DGMANHCO_00914 6.6e-187 bfmBAA 1.2.4.4 C Dehydrogenase E1 component
DGMANHCO_00915 3.7e-182 bfmBAB 1.2.4.1, 1.2.4.4 C Transketolase, pyrimidine binding domain
DGMANHCO_00916 1.9e-205 bfmBB 2.3.1.168, 2.3.1.61 C 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
DGMANHCO_00917 2.4e-178 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DGMANHCO_00918 3.4e-195 pfoS S Phosphotransferase system, EIIC
DGMANHCO_00919 1.5e-49 S MazG-like family
DGMANHCO_00920 0.0 FbpA K Fibronectin-binding protein
DGMANHCO_00921 5.9e-160 degV S EDD domain protein, DegV family
DGMANHCO_00922 4.5e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
DGMANHCO_00923 2e-205 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGMANHCO_00924 1.4e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DGMANHCO_00925 1.9e-110 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DGMANHCO_00926 2.8e-230 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DGMANHCO_00927 7e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
DGMANHCO_00928 2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DGMANHCO_00929 2.8e-123 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DGMANHCO_00930 2.3e-131 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DGMANHCO_00931 5.6e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DGMANHCO_00932 1.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
DGMANHCO_00933 1e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DGMANHCO_00934 3.7e-111 nfnB 1.5.1.34 C Nitroreductase family
DGMANHCO_00935 2.4e-62 K Acetyltransferase (GNAT) domain
DGMANHCO_00936 5.3e-47 msi198 K Acetyltransferase (GNAT) domain
DGMANHCO_00937 6.8e-190 EGP Transmembrane secretion effector
DGMANHCO_00938 1.4e-122 T Transcriptional regulatory protein, C terminal
DGMANHCO_00939 2.3e-173 T PhoQ Sensor
DGMANHCO_00940 6.3e-137 XK27_05695 V ABC transporter, ATP-binding protein
DGMANHCO_00941 0.0 ysaB V FtsX-like permease family
DGMANHCO_00942 8.1e-39
DGMANHCO_00943 1.1e-209 xerS L Belongs to the 'phage' integrase family
DGMANHCO_00944 1.8e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
DGMANHCO_00945 3.4e-180 K LysR substrate binding domain
DGMANHCO_00946 5.6e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DGMANHCO_00947 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
DGMANHCO_00948 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DGMANHCO_00949 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DGMANHCO_00950 1.7e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DGMANHCO_00951 1.8e-172 lacX 5.1.3.3 G Aldose 1-epimerase
DGMANHCO_00952 1.2e-258 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DGMANHCO_00953 7.2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DGMANHCO_00954 2.1e-168 xerC D Belongs to the 'phage' integrase family. XerC subfamily
DGMANHCO_00955 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DGMANHCO_00956 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DGMANHCO_00957 1.9e-144 dprA LU DNA protecting protein DprA
DGMANHCO_00958 1.1e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DGMANHCO_00959 1.9e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DGMANHCO_00960 4.5e-49 K Helix-turn-helix domain
DGMANHCO_00961 9.3e-240 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
DGMANHCO_00962 1.1e-39 yozE S Belongs to the UPF0346 family
DGMANHCO_00963 1.7e-84 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DGMANHCO_00964 1.2e-112 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
DGMANHCO_00965 4.5e-152 ypmR E GDSL-like Lipase/Acylhydrolase
DGMANHCO_00966 1.5e-145 DegV S EDD domain protein, DegV family
DGMANHCO_00967 2.1e-114 hly S protein, hemolysin III
DGMANHCO_00968 2.2e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DGMANHCO_00969 2.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DGMANHCO_00970 0.0 yfmR S ABC transporter, ATP-binding protein
DGMANHCO_00971 1.3e-84
DGMANHCO_00972 3.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DGMANHCO_00973 2.6e-147 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DGMANHCO_00974 2.3e-237 S Tetratricopeptide repeat protein
DGMANHCO_00975 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DGMANHCO_00976 1e-243 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DGMANHCO_00977 2.1e-225 rpsA 1.17.7.4 J Ribosomal protein S1
DGMANHCO_00978 2e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DGMANHCO_00979 6.1e-66 M Lysin motif
DGMANHCO_00980 3.2e-264 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
DGMANHCO_00981 5.3e-181 ypbB 5.1.3.1 S Helix-turn-helix domain
DGMANHCO_00982 2.7e-44 fer C 4Fe-4S single cluster domain of Ferredoxin I
DGMANHCO_00983 1.3e-173 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DGMANHCO_00984 1e-54 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
DGMANHCO_00985 3.3e-172 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DGMANHCO_00986 2.6e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DGMANHCO_00987 1.6e-126 spl M NlpC/P60 family
DGMANHCO_00988 1.9e-68 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
DGMANHCO_00989 1e-110 gmk2 2.7.4.8 F Guanylate kinase
DGMANHCO_00990 6.3e-09
DGMANHCO_00991 6.1e-84 zur P Belongs to the Fur family
DGMANHCO_00993 1.1e-173
DGMANHCO_00994 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DGMANHCO_00995 3.8e-148 glnH ET ABC transporter substrate-binding protein
DGMANHCO_00996 4.6e-109 gluC P ABC transporter permease
DGMANHCO_00997 7.4e-110 glnP P ABC transporter permease
DGMANHCO_00998 4.6e-174 cps2D 5.1.3.2 M RmlD substrate binding domain
DGMANHCO_00999 4.1e-259 wcaJ M Bacterial sugar transferase
DGMANHCO_01000 1.4e-121
DGMANHCO_01002 0.0 fbp 3.1.3.11 G phosphatase activity
DGMANHCO_01003 1.8e-145 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DGMANHCO_01004 1.6e-99 ylcC 3.4.22.70 M Sortase family
DGMANHCO_01005 1.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
DGMANHCO_01006 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DGMANHCO_01007 3.6e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DGMANHCO_01008 3.6e-200 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
DGMANHCO_01009 8.9e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
DGMANHCO_01010 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DGMANHCO_01011 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
DGMANHCO_01012 2.1e-52 czrA K Transcriptional regulator, ArsR family
DGMANHCO_01013 6.4e-111 2.5.1.105 P Cation efflux family
DGMANHCO_01014 3.6e-25
DGMANHCO_01015 0.0 mco Q Multicopper oxidase
DGMANHCO_01016 1.7e-238 EGP Major Facilitator Superfamily
DGMANHCO_01017 7.5e-56
DGMANHCO_01018 0.0 pacL P P-type ATPase
DGMANHCO_01019 6.5e-261 mntH P H( )-stimulated, divalent metal cation uptake system
DGMANHCO_01020 4.5e-20
DGMANHCO_01021 1.5e-135
DGMANHCO_01022 1.1e-253 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DGMANHCO_01023 1.9e-217 yqiG C Oxidoreductase
DGMANHCO_01024 2.2e-118 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DGMANHCO_01025 1.5e-180 S Aldo keto reductase
DGMANHCO_01029 3.5e-46 yceJ EGP Major facilitator Superfamily
DGMANHCO_01030 2.4e-107 K Transcriptional
DGMANHCO_01031 9.6e-106 tag 3.2.2.20 L glycosylase
DGMANHCO_01032 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
DGMANHCO_01033 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
DGMANHCO_01034 1.3e-195 V Beta-lactamase
DGMANHCO_01035 1.9e-144 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
DGMANHCO_01036 1.3e-19 H Protein of unknown function (DUF1698)
DGMANHCO_01037 1.2e-94 H Protein of unknown function (DUF1698)
DGMANHCO_01038 5.7e-143 puuD S peptidase C26
DGMANHCO_01039 1.2e-255 6.3.1.2 E Glutamine synthetase, catalytic domain
DGMANHCO_01040 2.1e-221 S Amidohydrolase
DGMANHCO_01041 5.3e-248 E Amino acid permease
DGMANHCO_01042 6.5e-75 K helix_turn_helix, mercury resistance
DGMANHCO_01043 1.5e-163 morA2 S reductase
DGMANHCO_01044 4.5e-199 qor 1.1.1.1, 1.6.5.5 C Zinc-binding dehydrogenase
DGMANHCO_01045 8.4e-57 hxlR K HxlR-like helix-turn-helix
DGMANHCO_01046 1.7e-32 S Phospholipase A2
DGMANHCO_01047 7e-178 V ABC transporter transmembrane region
DGMANHCO_01048 3.4e-147 EG EamA-like transporter family
DGMANHCO_01049 4.5e-73 3.6.1.55 L NUDIX domain
DGMANHCO_01050 2.5e-62
DGMANHCO_01051 3.7e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DGMANHCO_01052 7.8e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DGMANHCO_01053 1.5e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
DGMANHCO_01054 1.2e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DGMANHCO_01055 2.1e-70 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DGMANHCO_01056 2.8e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DGMANHCO_01057 2e-166 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DGMANHCO_01058 6.7e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DGMANHCO_01059 1.5e-16
DGMANHCO_01060 7.4e-57 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
DGMANHCO_01061 1.3e-48
DGMANHCO_01062 2.6e-52 ybjQ S Belongs to the UPF0145 family
DGMANHCO_01063 4.8e-160 3.5.1.10 C nadph quinone reductase
DGMANHCO_01064 2.8e-246 amt P ammonium transporter
DGMANHCO_01065 2.4e-178 yfeX P Peroxidase
DGMANHCO_01066 2e-118 yhiD S MgtC family
DGMANHCO_01067 2.1e-114 F DNA RNA non-specific endonuclease
DGMANHCO_01068 0.0 ybiT S ABC transporter, ATP-binding protein
DGMANHCO_01069 0.0 mutS L ATPase domain of DNA mismatch repair MUTS family
DGMANHCO_01070 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
DGMANHCO_01071 2.6e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DGMANHCO_01072 6.7e-302 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
DGMANHCO_01073 2.1e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DGMANHCO_01074 2.3e-86 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
DGMANHCO_01076 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
DGMANHCO_01077 9.9e-146 3.5.2.6 V Beta-lactamase enzyme family
DGMANHCO_01078 8e-191 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
DGMANHCO_01079 7.4e-194 blaA6 V Beta-lactamase
DGMANHCO_01080 1.6e-155 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DGMANHCO_01081 8.9e-162 ybbH_2 K Helix-turn-helix domain, rpiR family
DGMANHCO_01082 3.1e-81 2.7.1.191 G PTS system sorbose subfamily IIB component
DGMANHCO_01083 8.3e-151 G PTS system mannose/fructose/sorbose family IID component
DGMANHCO_01084 2e-128 G PTS system sorbose-specific iic component
DGMANHCO_01085 1.5e-200 S endonuclease exonuclease phosphatase family protein
DGMANHCO_01086 1.7e-173 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
DGMANHCO_01087 3.1e-54
DGMANHCO_01088 3.4e-242 mntH P H( )-stimulated, divalent metal cation uptake system
DGMANHCO_01089 1.2e-112 K Bacterial regulatory proteins, tetR family
DGMANHCO_01090 9.1e-164 corA P CorA-like Mg2+ transporter protein
DGMANHCO_01091 2.6e-101 S Protein of unknown function (DUF1211)
DGMANHCO_01092 6.1e-124 S membrane transporter protein
DGMANHCO_01093 3e-48
DGMANHCO_01094 5.9e-154 supH G Sucrose-6F-phosphate phosphohydrolase
DGMANHCO_01095 5.4e-98 K transcriptional regulator
DGMANHCO_01096 2.8e-128 macB V ABC transporter, ATP-binding protein
DGMANHCO_01097 0.0 ylbB V ABC transporter permease
DGMANHCO_01098 4.7e-110 usp 3.5.1.28 CBM50 D CHAP domain
DGMANHCO_01101 1.1e-104 S Protein of unknown function (DUF1211)
DGMANHCO_01104 0.0 gshF 6.3.2.2, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
DGMANHCO_01105 6e-76 yueI S Protein of unknown function (DUF1694)
DGMANHCO_01106 2.2e-108 yktB S Belongs to the UPF0637 family
DGMANHCO_01107 7.6e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
DGMANHCO_01108 2.8e-149 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DGMANHCO_01109 4.3e-121 G alpha-ribazole phosphatase activity
DGMANHCO_01110 5.2e-153 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DGMANHCO_01111 2.1e-171 IQ NAD dependent epimerase/dehydratase family
DGMANHCO_01112 1.6e-137 pnuC H nicotinamide mononucleotide transporter
DGMANHCO_01113 5.2e-133 dck 2.7.1.74 F deoxynucleoside kinase
DGMANHCO_01114 1.2e-157 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
DGMANHCO_01115 0.0 oppA E ABC transporter, substratebinding protein
DGMANHCO_01116 1.9e-156 T GHKL domain
DGMANHCO_01117 4.9e-117 T Transcriptional regulatory protein, C terminal
DGMANHCO_01118 1.3e-61
DGMANHCO_01119 4.4e-52
DGMANHCO_01120 5.8e-267 frdC 1.3.5.4 C HI0933-like protein
DGMANHCO_01122 1.2e-198 GKT transcriptional antiterminator
DGMANHCO_01123 5.8e-49 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
DGMANHCO_01124 9.3e-210 ulaA 2.7.1.194 S PTS system sugar-specific permease component
DGMANHCO_01125 3.6e-70
DGMANHCO_01126 7.5e-163 4.1.2.13 G Fructose-bisphosphate aldolase class-II
DGMANHCO_01127 1.3e-114 6.3.4.4 S Zeta toxin
DGMANHCO_01128 2.9e-156 K Sugar-specific transcriptional regulator TrmB
DGMANHCO_01129 5.8e-147 S Sulfite exporter TauE/SafE
DGMANHCO_01130 1.1e-178 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
DGMANHCO_01131 5.8e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
DGMANHCO_01132 2e-186 tdcB 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DGMANHCO_01133 1.4e-294 S OPT oligopeptide transporter protein
DGMANHCO_01134 4e-62 S Coenzyme PQQ synthesis protein D (PqqD)
DGMANHCO_01135 1.5e-280 pipD E Dipeptidase
DGMANHCO_01136 1.1e-258 gor 1.8.1.7 C Glutathione reductase
DGMANHCO_01137 4.7e-247 lmrB EGP Major facilitator Superfamily
DGMANHCO_01138 1.5e-95 yxaF K Bacterial regulatory proteins, tetR family
DGMANHCO_01139 1.4e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DGMANHCO_01140 1.2e-272 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DGMANHCO_01141 1.5e-69 3.4.22.70 M Sortase family
DGMANHCO_01142 2.9e-229 ywhK S Membrane
DGMANHCO_01143 3.1e-42
DGMANHCO_01145 1.1e-147 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DGMANHCO_01146 1.2e-201 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DGMANHCO_01147 1.7e-224 pimH EGP Major facilitator Superfamily
DGMANHCO_01148 1.3e-38
DGMANHCO_01149 9.6e-32
DGMANHCO_01150 7e-08
DGMANHCO_01151 1e-09 yhjA K CsbD-like
DGMANHCO_01152 4.6e-205 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
DGMANHCO_01153 7.2e-46
DGMANHCO_01154 6e-205 ltrA S Bacterial low temperature requirement A protein (LtrA)
DGMANHCO_01155 7.7e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DGMANHCO_01156 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DGMANHCO_01157 7.9e-223 mesE M Transport protein ComB
DGMANHCO_01158 1.4e-59
DGMANHCO_01160 1.5e-250 yjjP S Putative threonine/serine exporter
DGMANHCO_01161 2.8e-45 spiA K TRANSCRIPTIONal
DGMANHCO_01162 3.6e-45 S Enterocin A Immunity
DGMANHCO_01163 5.4e-46 S Enterocin A Immunity
DGMANHCO_01164 3.8e-137
DGMANHCO_01165 6.6e-65
DGMANHCO_01166 2.2e-54 K Transcriptional regulator PadR-like family
DGMANHCO_01167 8.8e-113 K Helix-turn-helix XRE-family like proteins
DGMANHCO_01168 1e-206 MA20_36090 S Protein of unknown function (DUF2974)
DGMANHCO_01169 4e-231 N Uncharacterized conserved protein (DUF2075)
DGMANHCO_01170 1.3e-117 mprF 2.3.2.3 M lysyltransferase activity
DGMANHCO_01172 1.3e-204 S Calcineurin-like phosphoesterase
DGMANHCO_01173 2.8e-160 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
DGMANHCO_01174 5.1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DGMANHCO_01175 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DGMANHCO_01176 3.7e-165 natA S abc transporter atp-binding protein
DGMANHCO_01177 8.9e-221 ysdA CP ABC-2 family transporter protein
DGMANHCO_01178 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
DGMANHCO_01179 1.1e-161 CcmA V ABC transporter
DGMANHCO_01180 1e-111 I ABC-2 family transporter protein
DGMANHCO_01181 8.9e-147 IQ reductase
DGMANHCO_01190 2.1e-94 sigH K DNA-templated transcription, initiation
DGMANHCO_01191 3.8e-283 ybeC E amino acid
DGMANHCO_01193 1.2e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
DGMANHCO_01194 1.2e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
DGMANHCO_01195 1.9e-165 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DGMANHCO_01197 7.7e-219 patA 2.6.1.1 E Aminotransferase
DGMANHCO_01198 1.9e-43 ykuJ S Protein of unknown function (DUF1797)
DGMANHCO_01199 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DGMANHCO_01200 4e-80 perR P Belongs to the Fur family
DGMANHCO_01201 1.3e-22 S Bacteriophage abortive infection AbiH
DGMANHCO_01204 2.8e-188 K DNA-binding helix-turn-helix protein
DGMANHCO_01205 1.5e-58 K Transcriptional regulator PadR-like family
DGMANHCO_01206 1.2e-41 ygbF S Sugar efflux transporter for intercellular exchange
DGMANHCO_01207 8.7e-42
DGMANHCO_01208 3.1e-192 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
DGMANHCO_01210 3.5e-53
DGMANHCO_01211 7.5e-80
DGMANHCO_01212 3.2e-209 yubA S AI-2E family transporter
DGMANHCO_01213 3.1e-24
DGMANHCO_01214 5.7e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DGMANHCO_01215 2.7e-45
DGMANHCO_01216 2.1e-166 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
DGMANHCO_01217 3.3e-88 ywrF S Flavin reductase like domain
DGMANHCO_01219 7.8e-134
DGMANHCO_01220 6e-20 E Zn peptidase
DGMANHCO_01221 7.5e-61 ps115 K Helix-turn-helix XRE-family like proteins
DGMANHCO_01224 7.2e-155 ps305 S Protein of unknown function (Hypoth_ymh)
DGMANHCO_01225 1.1e-138 S ORF6N domain
DGMANHCO_01227 7.8e-44 S Domain of unknown function (DUF1883)
DGMANHCO_01233 6e-51 L Helix-turn-helix domain
DGMANHCO_01234 2.5e-74 L Helix-turn-helix domain
DGMANHCO_01235 9.3e-155 dnaC L IstB-like ATP binding protein
DGMANHCO_01237 2.1e-70
DGMANHCO_01238 1.5e-132
DGMANHCO_01241 1.5e-155 mleR K LysR family
DGMANHCO_01242 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
DGMANHCO_01243 3.2e-170 mleP S Sodium Bile acid symporter family
DGMANHCO_01244 1.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DGMANHCO_01245 5.5e-86 C FMN binding
DGMANHCO_01246 1.7e-171 K Helix-turn-helix XRE-family like proteins
DGMANHCO_01247 9.3e-226 V ABC transporter transmembrane region
DGMANHCO_01248 3.2e-49 V ABC transporter transmembrane region
DGMANHCO_01249 0.0 pepF E Oligopeptidase F
DGMANHCO_01250 4.1e-59
DGMANHCO_01251 6.3e-154 S Uncharacterised protein, DegV family COG1307
DGMANHCO_01252 1.2e-103 desR K helix_turn_helix, Lux Regulon
DGMANHCO_01253 9.6e-203 desK 2.7.13.3 T Histidine kinase
DGMANHCO_01254 6.5e-134 yvfS V ABC-2 type transporter
DGMANHCO_01255 4.4e-158 yvfR V ABC transporter
DGMANHCO_01256 1.4e-208
DGMANHCO_01257 1e-66 K helix_turn_helix, mercury resistance
DGMANHCO_01258 4.8e-46 S Protein of unknown function (DUF2568)
DGMANHCO_01259 8.5e-231
DGMANHCO_01260 2.3e-139
DGMANHCO_01261 0.0 D Putative exonuclease SbcCD, C subunit
DGMANHCO_01262 3e-129 S Protein of unknown function C-terminus (DUF2399)
DGMANHCO_01263 4.9e-11
DGMANHCO_01264 0.0 yhgF K Tex-like protein N-terminal domain protein
DGMANHCO_01265 2.4e-69 K Cro/C1-type HTH DNA-binding domain
DGMANHCO_01266 6.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DGMANHCO_01267 5.1e-84 ytsP 1.8.4.14 T GAF domain-containing protein
DGMANHCO_01268 2.5e-271 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DGMANHCO_01269 9.6e-214 iscS2 2.8.1.7 E Aminotransferase class V
DGMANHCO_01270 1.1e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DGMANHCO_01271 6.3e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DGMANHCO_01272 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DGMANHCO_01273 2.3e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DGMANHCO_01274 1.1e-113 S Haloacid dehalogenase-like hydrolase
DGMANHCO_01275 2e-118 radC L DNA repair protein
DGMANHCO_01276 1e-179 mreB D cell shape determining protein MreB
DGMANHCO_01277 2.1e-149 mreC M Involved in formation and maintenance of cell shape
DGMANHCO_01278 2.3e-85 mreD M rod shape-determining protein MreD
DGMANHCO_01279 2.2e-114 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
DGMANHCO_01280 2.6e-141 minD D Belongs to the ParA family
DGMANHCO_01281 1.2e-109 artQ P ABC transporter permease
DGMANHCO_01282 1.5e-112 glnQ 3.6.3.21 E ABC transporter
DGMANHCO_01283 1.2e-151 aatB ET ABC transporter substrate-binding protein
DGMANHCO_01284 3.1e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DGMANHCO_01285 4.2e-45
DGMANHCO_01286 9.8e-79 mraZ K Belongs to the MraZ family
DGMANHCO_01287 2.4e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DGMANHCO_01288 3.1e-49 ftsL D cell division protein FtsL
DGMANHCO_01289 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
DGMANHCO_01290 7.5e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DGMANHCO_01291 6e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DGMANHCO_01292 2.5e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DGMANHCO_01293 5.7e-155 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DGMANHCO_01294 2.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DGMANHCO_01295 3.1e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DGMANHCO_01296 8.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DGMANHCO_01297 2.4e-44 yggT S integral membrane protein
DGMANHCO_01298 5.7e-146 ylmH S S4 domain protein
DGMANHCO_01299 5.7e-85 divIVA D DivIVA protein
DGMANHCO_01300 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DGMANHCO_01301 6.9e-36 cspA K Cold shock protein
DGMANHCO_01302 6.7e-154 pstS P Phosphate
DGMANHCO_01303 2.4e-262 ydiC1 EGP Major facilitator Superfamily
DGMANHCO_01304 6.7e-210 yaaN P Toxic anion resistance protein (TelA)
DGMANHCO_01305 2e-115 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
DGMANHCO_01306 1.4e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
DGMANHCO_01307 4.3e-29
DGMANHCO_01308 4.8e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DGMANHCO_01309 1.3e-218 iscS 2.8.1.7 E Aminotransferase class V
DGMANHCO_01310 8.3e-57 XK27_04120 S Putative amino acid metabolism
DGMANHCO_01311 0.0 uvrA2 L ABC transporter
DGMANHCO_01312 1.5e-245 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DGMANHCO_01313 9.9e-123 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
DGMANHCO_01314 5.3e-116 S Repeat protein
DGMANHCO_01315 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DGMANHCO_01316 1.4e-244 els S Sterol carrier protein domain
DGMANHCO_01317 6.1e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
DGMANHCO_01318 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DGMANHCO_01319 2.9e-31 ykzG S Belongs to the UPF0356 family
DGMANHCO_01320 9.5e-69
DGMANHCO_01321 1.3e-45
DGMANHCO_01322 2.9e-99 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DGMANHCO_01323 5.2e-89 S E1-E2 ATPase
DGMANHCO_01324 2.5e-211 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
DGMANHCO_01325 1.4e-181 pdhB 1.2.4.1, 1.2.4.4 C Transketolase, C-terminal domain protein
DGMANHCO_01326 1.2e-265 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DGMANHCO_01327 2.4e-259 lpdA 1.8.1.4 C Dehydrogenase
DGMANHCO_01328 1.1e-156 1.1.1.27 C L-malate dehydrogenase activity
DGMANHCO_01329 2.4e-46 yktA S Belongs to the UPF0223 family
DGMANHCO_01330 1.3e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
DGMANHCO_01331 0.0 typA T GTP-binding protein TypA
DGMANHCO_01332 2.2e-210 ftsW D Belongs to the SEDS family
DGMANHCO_01333 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DGMANHCO_01334 2.5e-62 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
DGMANHCO_01335 5.9e-100 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
DGMANHCO_01336 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DGMANHCO_01337 1.4e-181 ylbL T Belongs to the peptidase S16 family
DGMANHCO_01338 1.1e-111 comEA L Competence protein ComEA
DGMANHCO_01339 0.0 comEC S Competence protein ComEC
DGMANHCO_01340 1e-169 holA 2.7.7.7 L DNA polymerase III delta subunit
DGMANHCO_01341 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
DGMANHCO_01342 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DGMANHCO_01343 1.8e-50
DGMANHCO_01344 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DGMANHCO_01345 1.4e-164 S Tetratricopeptide repeat
DGMANHCO_01346 2.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DGMANHCO_01347 1.2e-55
DGMANHCO_01348 1.9e-147 levD G PTS system mannose/fructose/sorbose family IID component
DGMANHCO_01349 1.6e-152 M PTS system sorbose-specific iic component
DGMANHCO_01350 4.8e-90 2.7.1.191 G PTS system sorbose subfamily IIB component
DGMANHCO_01351 5.3e-72 levA G PTS system fructose IIA component
DGMANHCO_01352 0.0 K Sigma-54 interaction domain
DGMANHCO_01354 8.8e-27
DGMANHCO_01355 1.2e-86
DGMANHCO_01356 1.8e-135 mga K M protein trans-acting positive regulator
DGMANHCO_01357 1.7e-149 ugpB G Bacterial extracellular solute-binding protein
DGMANHCO_01358 3.4e-149 ugpE G ABC transporter permease
DGMANHCO_01359 3.3e-80 ugpA P ABC-type sugar transport systems, permease components
DGMANHCO_01360 1.9e-64 ugpA P ABC-type sugar transport systems, permease components
DGMANHCO_01361 1.5e-211 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
DGMANHCO_01362 2.4e-267 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DGMANHCO_01363 9.9e-108 pncA Q Isochorismatase family
DGMANHCO_01364 9.5e-135 3.6.1.13, 3.6.1.55 F NUDIX domain
DGMANHCO_01365 7.3e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DGMANHCO_01366 3.5e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DGMANHCO_01367 5e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DGMANHCO_01368 3e-162 S WxL domain surface cell wall-binding
DGMANHCO_01369 5e-185 S Bacterial protein of unknown function (DUF916)
DGMANHCO_01370 1e-156 S Protein of unknown function C-terminal (DUF3324)
DGMANHCO_01371 0.0 S Leucine-rich repeat (LRR) protein
DGMANHCO_01372 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DGMANHCO_01373 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DGMANHCO_01374 3e-240 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DGMANHCO_01375 9.3e-70 yabR J RNA binding
DGMANHCO_01376 1.1e-66 divIC D cell cycle
DGMANHCO_01377 2.7e-39 yabO J S4 domain protein
DGMANHCO_01378 9.5e-281 yabM S Polysaccharide biosynthesis protein
DGMANHCO_01379 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DGMANHCO_01380 1.1e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DGMANHCO_01381 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DGMANHCO_01382 1.5e-261 S Putative peptidoglycan binding domain
DGMANHCO_01383 2.3e-119 S (CBS) domain
DGMANHCO_01384 1.8e-99 yciB M ErfK YbiS YcfS YnhG
DGMANHCO_01386 3e-119 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DGMANHCO_01387 9.5e-132 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DGMANHCO_01388 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
DGMANHCO_01389 3.3e-68 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
DGMANHCO_01390 1.1e-84 S QueT transporter
DGMANHCO_01391 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
DGMANHCO_01392 5.2e-32
DGMANHCO_01393 9.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DGMANHCO_01394 8.5e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DGMANHCO_01395 7e-265 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DGMANHCO_01397 8.7e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DGMANHCO_01398 1.1e-144
DGMANHCO_01399 9.6e-123 S Tetratricopeptide repeat
DGMANHCO_01400 4.1e-124
DGMANHCO_01401 1.2e-65
DGMANHCO_01402 2.5e-42 rpmE2 J Ribosomal protein L31
DGMANHCO_01403 1.6e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DGMANHCO_01404 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DGMANHCO_01405 1.3e-157 S Protein of unknown function (DUF1211)
DGMANHCO_01406 1.7e-53 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DGMANHCO_01407 1e-78 ywiB S Domain of unknown function (DUF1934)
DGMANHCO_01408 4.3e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
DGMANHCO_01409 7.9e-268 ywfO S HD domain protein
DGMANHCO_01410 2.4e-80 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
DGMANHCO_01411 1.8e-179 S DUF218 domain
DGMANHCO_01412 2.1e-53 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DGMANHCO_01413 7.2e-209 Q Imidazolonepropionase and related amidohydrolases
DGMANHCO_01414 1.7e-233 dapE 3.5.1.18 E Peptidase dimerisation domain
DGMANHCO_01415 9.6e-193 E glutamate:sodium symporter activity
DGMANHCO_01416 2.6e-55 nudA S ASCH
DGMANHCO_01417 1.3e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DGMANHCO_01418 6.5e-217 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DGMANHCO_01419 5.4e-220 ysaA V RDD family
DGMANHCO_01420 1e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
DGMANHCO_01421 7.7e-120 ybbL S ABC transporter, ATP-binding protein
DGMANHCO_01422 9e-120 ybbM S Uncharacterised protein family (UPF0014)
DGMANHCO_01423 1.3e-159 czcD P cation diffusion facilitator family transporter
DGMANHCO_01424 6.7e-181 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DGMANHCO_01425 1.1e-37 veg S Biofilm formation stimulator VEG
DGMANHCO_01426 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DGMANHCO_01427 7.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DGMANHCO_01428 1.8e-147 tatD L hydrolase, TatD family
DGMANHCO_01429 5.8e-80 manR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
DGMANHCO_01430 5.6e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
DGMANHCO_01431 2.4e-172 yqhA G Aldose 1-epimerase
DGMANHCO_01432 4.7e-123 T LytTr DNA-binding domain
DGMANHCO_01433 3.6e-139 2.7.13.3 T GHKL domain
DGMANHCO_01434 0.0 V ABC transporter
DGMANHCO_01435 0.0 V ABC transporter
DGMANHCO_01436 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DGMANHCO_01437 4.3e-174 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
DGMANHCO_01438 7.3e-152 yunF F Protein of unknown function DUF72
DGMANHCO_01439 1.2e-90 3.6.1.55 F NUDIX domain
DGMANHCO_01440 6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DGMANHCO_01441 1.6e-106 yiiE S Protein of unknown function (DUF1211)
DGMANHCO_01442 2.4e-127 cobB K Sir2 family
DGMANHCO_01443 1.4e-16
DGMANHCO_01444 6.1e-171
DGMANHCO_01445 9.4e-97 yxkA S Phosphatidylethanolamine-binding protein
DGMANHCO_01446 1.6e-18
DGMANHCO_01447 1.1e-149 ypuA S Protein of unknown function (DUF1002)
DGMANHCO_01448 2.7e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
DGMANHCO_01449 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DGMANHCO_01450 2.1e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
DGMANHCO_01451 2.9e-176 S Aldo keto reductase
DGMANHCO_01452 1.4e-153 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
DGMANHCO_01453 8.1e-93 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
DGMANHCO_01454 0.0 S Bacterial membrane protein YfhO
DGMANHCO_01455 4.1e-150 licT2 K CAT RNA binding domain
DGMANHCO_01456 0.0 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
DGMANHCO_01457 2.2e-284 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DGMANHCO_01458 1e-115 ywqD 2.7.10.1 D Capsular exopolysaccharide family
DGMANHCO_01459 4.6e-134 epsB M biosynthesis protein
DGMANHCO_01460 2.8e-131 E lipolytic protein G-D-S-L family
DGMANHCO_01461 1.4e-81 ccl S QueT transporter
DGMANHCO_01462 1.3e-125 IQ Enoyl-(Acyl carrier protein) reductase
DGMANHCO_01463 3.7e-37 XK27_01315 S Protein of unknown function (DUF2829)
DGMANHCO_01464 7.5e-47 K sequence-specific DNA binding
DGMANHCO_01465 1.7e-116 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
DGMANHCO_01466 1.3e-179 oppF P Belongs to the ABC transporter superfamily
DGMANHCO_01467 1.1e-197 oppD P Belongs to the ABC transporter superfamily
DGMANHCO_01468 2.5e-178 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
DGMANHCO_01469 8e-163 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
DGMANHCO_01470 5.9e-302 oppA E ABC transporter, substratebinding protein
DGMANHCO_01471 9.9e-253 EGP Major facilitator Superfamily
DGMANHCO_01472 1.3e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DGMANHCO_01473 7.3e-132 yrjD S LUD domain
DGMANHCO_01474 1.7e-287 lutB C 4Fe-4S dicluster domain
DGMANHCO_01475 1.2e-148 lutA C Cysteine-rich domain
DGMANHCO_01476 4.5e-84
DGMANHCO_01477 5.1e-51 chbA 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
DGMANHCO_01478 7.2e-211 S Bacterial protein of unknown function (DUF871)
DGMANHCO_01479 4.3e-68 S Domain of unknown function (DUF3284)
DGMANHCO_01480 4.8e-07
DGMANHCO_01481 6.6e-265 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DGMANHCO_01483 0.0 rafA 3.2.1.22 G alpha-galactosidase
DGMANHCO_01484 7.7e-132 S Belongs to the UPF0246 family
DGMANHCO_01485 3.2e-130 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
DGMANHCO_01486 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
DGMANHCO_01487 1.4e-80
DGMANHCO_01488 2.4e-59 S WxL domain surface cell wall-binding
DGMANHCO_01489 3e-145 frlD 2.7.1.218 G pfkB family carbohydrate kinase
DGMANHCO_01490 4.3e-104 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
DGMANHCO_01491 3.2e-139
DGMANHCO_01492 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
DGMANHCO_01493 0.0 S PglZ domain
DGMANHCO_01494 4.5e-281 2.1.1.72 V Eco57I restriction-modification methylase
DGMANHCO_01495 2.2e-175 L Belongs to the 'phage' integrase family
DGMANHCO_01496 0.0 2.1.1.72 V Eco57I restriction-modification methylase
DGMANHCO_01497 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
DGMANHCO_01498 5.9e-95 S Domain of unknown function (DUF1788)
DGMANHCO_01499 7.2e-72 S Putative inner membrane protein (DUF1819)
DGMANHCO_01500 2.4e-212 ykiI
DGMANHCO_01501 0.0 scrA 2.7.1.211 G phosphotransferase system
DGMANHCO_01502 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
DGMANHCO_01503 3.2e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
DGMANHCO_01504 6.3e-303 scrB 3.2.1.26 GH32 G invertase
DGMANHCO_01505 7.1e-164 azoB GM NmrA-like family
DGMANHCO_01506 8.5e-234 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
DGMANHCO_01507 2.2e-142 accA 2.1.3.15, 6.4.1.2 I alpha subunit
DGMANHCO_01508 2e-149 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DGMANHCO_01509 9.1e-256 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
DGMANHCO_01510 8.7e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DGMANHCO_01511 5.1e-62 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DGMANHCO_01512 1.2e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DGMANHCO_01513 4.7e-126 IQ reductase
DGMANHCO_01514 4.7e-163 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
DGMANHCO_01515 8.2e-174 fabK 1.3.1.9 S Nitronate monooxygenase
DGMANHCO_01516 1.2e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DGMANHCO_01517 5.9e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DGMANHCO_01518 6.2e-76 marR K Winged helix DNA-binding domain
DGMANHCO_01519 3.1e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
DGMANHCO_01520 1e-192 bioH 2.1.1.197, 3.1.1.85, 3.7.1.13, 3.7.1.9, 4.2.99.20 E Alpha/beta hydrolase family
DGMANHCO_01521 2.3e-226 bdhA C Iron-containing alcohol dehydrogenase
DGMANHCO_01522 1.4e-47 S Uncharacterized protein conserved in bacteria (DUF2316)
DGMANHCO_01523 9.1e-66 K MarR family
DGMANHCO_01524 1.3e-12 S response to antibiotic
DGMANHCO_01525 1.3e-110 S Putative esterase
DGMANHCO_01526 5.3e-198
DGMANHCO_01527 2.4e-104 rmaB K Transcriptional regulator, MarR family
DGMANHCO_01528 0.0 lmrA 3.6.3.44 V ABC transporter
DGMANHCO_01529 3.8e-84 F NUDIX domain
DGMANHCO_01530 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DGMANHCO_01531 3.8e-20
DGMANHCO_01532 1.8e-118 S zinc-ribbon domain
DGMANHCO_01533 4.4e-200 pbpX1 V Beta-lactamase
DGMANHCO_01534 1.2e-186 K AI-2E family transporter
DGMANHCO_01535 1.3e-128 srtA 3.4.22.70 M Sortase family
DGMANHCO_01537 7.6e-65 gtcA S Teichoic acid glycosylation protein
DGMANHCO_01538 6e-174 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
DGMANHCO_01539 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
DGMANHCO_01540 4.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DGMANHCO_01541 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DGMANHCO_01542 6.5e-45 ylxQ J ribosomal protein
DGMANHCO_01543 1.7e-45 ylxR K Protein of unknown function (DUF448)
DGMANHCO_01544 1.7e-195 nusA K Participates in both transcription termination and antitermination
DGMANHCO_01545 1.7e-84 rimP J Required for maturation of 30S ribosomal subunits
DGMANHCO_01546 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DGMANHCO_01547 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DGMANHCO_01548 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
DGMANHCO_01549 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
DGMANHCO_01550 2.7e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DGMANHCO_01551 1.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DGMANHCO_01552 5.9e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DGMANHCO_01553 1.5e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DGMANHCO_01554 1e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
DGMANHCO_01555 5.2e-46 yazA L GIY-YIG catalytic domain protein
DGMANHCO_01556 4.2e-130 yabB 2.1.1.223 L Methyltransferase small domain
DGMANHCO_01557 2.6e-123 plsC 2.3.1.51 I Acyltransferase
DGMANHCO_01558 4e-214 yfnA E Amino Acid
DGMANHCO_01559 6.7e-142 yejC S Protein of unknown function (DUF1003)
DGMANHCO_01560 0.0 mdlB V ABC transporter
DGMANHCO_01561 0.0 mdlA V ABC transporter
DGMANHCO_01562 4.8e-29 yneF S UPF0154 protein
DGMANHCO_01563 4e-37 ynzC S UPF0291 protein
DGMANHCO_01564 2.1e-19
DGMANHCO_01565 2.9e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DGMANHCO_01566 1.1e-144 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DGMANHCO_01567 2.2e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DGMANHCO_01568 2.2e-38 ylqC S Belongs to the UPF0109 family
DGMANHCO_01569 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DGMANHCO_01570 6.3e-231 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DGMANHCO_01571 3.8e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DGMANHCO_01573 8.8e-53
DGMANHCO_01574 1.4e-181 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DGMANHCO_01575 0.0 smc D Required for chromosome condensation and partitioning
DGMANHCO_01576 1.7e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DGMANHCO_01577 0.0 oppA1 E ABC transporter substrate-binding protein
DGMANHCO_01578 1.5e-137 oppC EP Binding-protein-dependent transport system inner membrane component
DGMANHCO_01579 9.2e-170 oppB P ABC transporter permease
DGMANHCO_01580 1.4e-178 oppF P Belongs to the ABC transporter superfamily
DGMANHCO_01581 5.7e-194 oppD P Belongs to the ABC transporter superfamily
DGMANHCO_01582 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DGMANHCO_01583 2.3e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DGMANHCO_01584 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DGMANHCO_01585 9.3e-311 yloV S DAK2 domain fusion protein YloV
DGMANHCO_01586 2.3e-57 asp S Asp23 family, cell envelope-related function
DGMANHCO_01587 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DGMANHCO_01588 2.1e-128 thiN 2.7.6.2 H thiamine pyrophosphokinase
DGMANHCO_01589 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DGMANHCO_01590 7.6e-174 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DGMANHCO_01591 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
DGMANHCO_01592 9.7e-135 stp 3.1.3.16 T phosphatase
DGMANHCO_01593 8.9e-256 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DGMANHCO_01594 2.2e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DGMANHCO_01595 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DGMANHCO_01596 2.1e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DGMANHCO_01597 1.3e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DGMANHCO_01598 1.9e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
DGMANHCO_01599 1.6e-91 rssA S Patatin-like phospholipase
DGMANHCO_01600 1.9e-49
DGMANHCO_01602 0.0 recN L May be involved in recombinational repair of damaged DNA
DGMANHCO_01603 2e-74 argR K Regulates arginine biosynthesis genes
DGMANHCO_01604 1e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DGMANHCO_01605 4.6e-149 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DGMANHCO_01606 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DGMANHCO_01607 7.7e-199 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DGMANHCO_01608 4.6e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DGMANHCO_01609 4.7e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DGMANHCO_01610 2.2e-76 yqhY S Asp23 family, cell envelope-related function
DGMANHCO_01611 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DGMANHCO_01613 2.7e-202 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DGMANHCO_01614 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DGMANHCO_01615 5.5e-56 ysxB J Cysteine protease Prp
DGMANHCO_01616 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
DGMANHCO_01617 3.2e-11
DGMANHCO_01618 1e-16
DGMANHCO_01620 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DGMANHCO_01621 5.4e-261 glnA 6.3.1.2 E glutamine synthetase
DGMANHCO_01622 1e-60 glnR K Transcriptional regulator
DGMANHCO_01623 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
DGMANHCO_01624 1.4e-239 ynbB 4.4.1.1 P aluminum resistance
DGMANHCO_01625 2.9e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DGMANHCO_01626 1.5e-25 WQ51_02665 S Protein of unknown function (DUF3042)
DGMANHCO_01627 2.6e-73 yqhL P Rhodanese-like protein
DGMANHCO_01628 5.4e-178 glk 2.7.1.2 G Glucokinase
DGMANHCO_01629 2.4e-40 yqgQ S Bacterial protein of unknown function (DUF910)
DGMANHCO_01630 7.3e-121 gluP 3.4.21.105 S Peptidase, S54 family
DGMANHCO_01631 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
DGMANHCO_01632 0.0 S Bacterial membrane protein YfhO
DGMANHCO_01633 2.1e-54 yneR S Belongs to the HesB IscA family
DGMANHCO_01634 6.9e-116 vraR K helix_turn_helix, Lux Regulon
DGMANHCO_01635 1.4e-179 vraS 2.7.13.3 T Histidine kinase
DGMANHCO_01636 3.2e-119 yvqF S Cell wall-active antibiotics response 4TMS YvqF
DGMANHCO_01637 6.9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DGMANHCO_01638 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
DGMANHCO_01639 5.2e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DGMANHCO_01640 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DGMANHCO_01641 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DGMANHCO_01642 6.3e-66 yodB K Transcriptional regulator, HxlR family
DGMANHCO_01643 7.3e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
DGMANHCO_01644 5.1e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DGMANHCO_01645 1.9e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DGMANHCO_01646 1.9e-173 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DGMANHCO_01647 1.5e-289 arlS 2.7.13.3 T Histidine kinase
DGMANHCO_01648 7.9e-123 K response regulator
DGMANHCO_01649 3.7e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DGMANHCO_01650 8e-38 yhcX S Psort location Cytoplasmic, score
DGMANHCO_01651 4.5e-97 yceD S Uncharacterized ACR, COG1399
DGMANHCO_01652 1.2e-208 ylbM S Belongs to the UPF0348 family
DGMANHCO_01653 3.2e-138 yccK Q ubiE/COQ5 methyltransferase family
DGMANHCO_01654 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DGMANHCO_01655 5.6e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
DGMANHCO_01656 5.7e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DGMANHCO_01657 3.8e-48 yhbY J RNA-binding protein
DGMANHCO_01658 2.1e-205 yqeH S Ribosome biogenesis GTPase YqeH
DGMANHCO_01659 2.9e-96 yqeG S HAD phosphatase, family IIIA
DGMANHCO_01660 1.6e-171 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DGMANHCO_01661 1.2e-190 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DGMANHCO_01662 3.6e-122 mhqD S Dienelactone hydrolase family
DGMANHCO_01663 1.3e-179 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
DGMANHCO_01664 1.2e-97 yvdD 3.2.2.10 S Belongs to the LOG family
DGMANHCO_01665 8.7e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DGMANHCO_01666 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DGMANHCO_01667 1.5e-77 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DGMANHCO_01668 8.2e-128 S SseB protein N-terminal domain
DGMANHCO_01669 1.6e-53
DGMANHCO_01670 2e-103 yrgI 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
DGMANHCO_01671 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DGMANHCO_01672 1.2e-171 dnaI L Primosomal protein DnaI
DGMANHCO_01673 1.5e-250 dnaB L replication initiation and membrane attachment
DGMANHCO_01674 7.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DGMANHCO_01675 2e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DGMANHCO_01676 7.9e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DGMANHCO_01677 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DGMANHCO_01678 4.2e-119 ybhL S Inhibitor of apoptosis-promoting Bax1
DGMANHCO_01679 2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DGMANHCO_01680 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
DGMANHCO_01681 7.4e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DGMANHCO_01682 1.5e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DGMANHCO_01684 1.8e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DGMANHCO_01685 1e-147 ytmP 2.7.1.89 M Choline/ethanolamine kinase
DGMANHCO_01687 1.7e-213 ecsB U ABC transporter
DGMANHCO_01688 3.1e-133 ecsA V ABC transporter, ATP-binding protein
DGMANHCO_01689 1e-75 hit FG histidine triad
DGMANHCO_01690 2.7e-61 yhaH S YtxH-like protein
DGMANHCO_01691 8.1e-160 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DGMANHCO_01692 4e-181 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
DGMANHCO_01693 3.9e-54 yheA S Control of competence regulator ComK, YlbF/YmcA
DGMANHCO_01694 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DGMANHCO_01695 1.8e-153 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DGMANHCO_01696 5.3e-75 argR K Regulates arginine biosynthesis genes
DGMANHCO_01697 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DGMANHCO_01699 1.2e-67
DGMANHCO_01700 2.1e-22
DGMANHCO_01701 1.3e-176 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
DGMANHCO_01702 0.0 glpQ 3.1.4.46 C phosphodiesterase
DGMANHCO_01703 1.1e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DGMANHCO_01704 3.2e-68 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DGMANHCO_01705 3.3e-135 yhfI S Metallo-beta-lactamase superfamily
DGMANHCO_01706 1.1e-92 traP 1.14.99.57, 6.2.1.3 S heme oxygenase (decyclizing) activity
DGMANHCO_01707 0.0 V ABC transporter (permease)
DGMANHCO_01708 9.7e-138 bceA V ABC transporter
DGMANHCO_01709 5.9e-123 K response regulator
DGMANHCO_01710 5.9e-205 T PhoQ Sensor
DGMANHCO_01711 1.6e-108 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DGMANHCO_01712 0.0 copB 3.6.3.4 P P-type ATPase
DGMANHCO_01713 5.1e-75 copR K Copper transport repressor CopY TcrY
DGMANHCO_01714 3.4e-233 purD 6.3.4.13 F Belongs to the GARS family
DGMANHCO_01715 1.1e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DGMANHCO_01716 7.8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DGMANHCO_01717 1.3e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DGMANHCO_01718 2.9e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DGMANHCO_01719 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DGMANHCO_01720 1.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DGMANHCO_01721 1.9e-40 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DGMANHCO_01722 5.8e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DGMANHCO_01723 2.5e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DGMANHCO_01724 3.2e-78 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DGMANHCO_01725 4.7e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
DGMANHCO_01726 1.1e-256 iolT EGP Major facilitator Superfamily
DGMANHCO_01727 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DGMANHCO_01728 2.7e-39 ptsH G phosphocarrier protein HPR
DGMANHCO_01729 2e-28
DGMANHCO_01730 0.0 clpE O Belongs to the ClpA ClpB family
DGMANHCO_01731 1.4e-44 XK27_09445 S Domain of unknown function (DUF1827)
DGMANHCO_01733 6.5e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DGMANHCO_01734 6.7e-243 hlyX S Transporter associated domain
DGMANHCO_01735 2.7e-195 yueF S AI-2E family transporter
DGMANHCO_01736 4e-72 S Acetyltransferase (GNAT) domain
DGMANHCO_01737 1.2e-94
DGMANHCO_01738 6.4e-104 ygaC J Belongs to the UPF0374 family
DGMANHCO_01739 8.7e-142 recX 2.4.1.337 GT4 S Regulatory protein RecX
DGMANHCO_01740 2.3e-292 frvR K transcriptional antiterminator
DGMANHCO_01741 2.9e-63
DGMANHCO_01742 9.8e-250 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DGMANHCO_01743 8.2e-79 F Nucleoside 2-deoxyribosyltransferase
DGMANHCO_01744 1.8e-133 K UTRA
DGMANHCO_01745 3.5e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DGMANHCO_01746 9.4e-253 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DGMANHCO_01747 3e-84
DGMANHCO_01748 2e-49 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
DGMANHCO_01749 6.9e-50 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
DGMANHCO_01750 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
DGMANHCO_01751 9.9e-219 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
DGMANHCO_01752 1.6e-201 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
DGMANHCO_01753 4.2e-209 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
DGMANHCO_01754 1.6e-48
DGMANHCO_01755 2.6e-160 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
DGMANHCO_01756 5.7e-103 V Restriction endonuclease
DGMANHCO_01757 5.8e-157 5.1.3.3 G converts alpha-aldose to the beta-anomer
DGMANHCO_01758 5.2e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
DGMANHCO_01759 1e-102 S ECF transporter, substrate-specific component
DGMANHCO_01761 2.1e-79 yodP 2.3.1.264 K Acetyltransferase GNAT Family
DGMANHCO_01762 8.1e-84 ydcK S Belongs to the SprT family
DGMANHCO_01763 1.9e-130 XK27_08845 S ABC transporter, ATP-binding protein
DGMANHCO_01764 4.2e-140 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
DGMANHCO_01765 3.3e-154 XK27_08835 S ABC transporter
DGMANHCO_01767 2.6e-71
DGMANHCO_01768 0.0 pacL 3.6.3.8 P P-type ATPase
DGMANHCO_01769 9.2e-217 V Beta-lactamase
DGMANHCO_01770 1.3e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DGMANHCO_01771 1e-196 V Beta-lactamase
DGMANHCO_01772 7.2e-275 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DGMANHCO_01773 5e-125 gntR1 K UbiC transcription regulator-associated domain protein
DGMANHCO_01774 2.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
DGMANHCO_01775 1.1e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DGMANHCO_01776 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
DGMANHCO_01779 2.4e-158 yjjH S Calcineurin-like phosphoesterase
DGMANHCO_01780 4.6e-266 dtpT U amino acid peptide transporter
DGMANHCO_01781 0.0 macB_3 V ABC transporter, ATP-binding protein
DGMANHCO_01782 3.1e-65
DGMANHCO_01783 3.4e-76 S function, without similarity to other proteins
DGMANHCO_01784 1.2e-263 G MFS/sugar transport protein
DGMANHCO_01785 3.2e-230 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
DGMANHCO_01786 1.6e-57
DGMANHCO_01787 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
DGMANHCO_01788 1.4e-17 S Virus attachment protein p12 family
DGMANHCO_01789 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
DGMANHCO_01790 1.5e-223 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DGMANHCO_01791 4.7e-304 frvR K Mga helix-turn-helix domain
DGMANHCO_01792 5.9e-296 frvR K Mga helix-turn-helix domain
DGMANHCO_01793 1.3e-263 lysP E amino acid
DGMANHCO_01794 6.3e-241 dinF V MatE
DGMANHCO_01795 7.3e-110 S TPM domain
DGMANHCO_01796 1e-102 lemA S LemA family
DGMANHCO_01797 1.6e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DGMANHCO_01798 1.5e-50 V efflux transmembrane transporter activity
DGMANHCO_01799 1.6e-142 V efflux transmembrane transporter activity
DGMANHCO_01800 1.4e-27 V ATPases associated with a variety of cellular activities
DGMANHCO_01801 5.3e-14
DGMANHCO_01802 3.6e-75 yhbS S acetyltransferase
DGMANHCO_01803 2.9e-271 T PhoQ Sensor
DGMANHCO_01804 2.1e-134 K response regulator
DGMANHCO_01805 5.8e-70 S SdpI/YhfL protein family
DGMANHCO_01808 0.0 rafA 3.2.1.22 G alpha-galactosidase
DGMANHCO_01809 2.8e-165 arbZ I Phosphate acyltransferases
DGMANHCO_01810 3.6e-182 arbY M family 8
DGMANHCO_01811 2.5e-163 arbx M Glycosyl transferase family 8
DGMANHCO_01812 6.7e-147 arbV 2.3.1.51 I Phosphate acyltransferases
DGMANHCO_01813 2.4e-256 cycA E Amino acid permease
DGMANHCO_01814 5.4e-51
DGMANHCO_01815 8.1e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
DGMANHCO_01816 9.7e-10
DGMANHCO_01817 1.9e-19
DGMANHCO_01818 2.5e-23
DGMANHCO_01820 2.5e-26
DGMANHCO_01821 6.9e-170 comGB NU type II secretion system
DGMANHCO_01822 2.7e-152 comGA NU Type II IV secretion system protein
DGMANHCO_01823 7.6e-132 yebC K Transcriptional regulatory protein
DGMANHCO_01824 1.5e-78 S VanZ like family
DGMANHCO_01825 0.0 pepF2 E Oligopeptidase F
DGMANHCO_01827 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DGMANHCO_01828 2.6e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DGMANHCO_01829 2.2e-164 ybbR S YbbR-like protein
DGMANHCO_01830 2.2e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DGMANHCO_01831 2.3e-128 V AAA domain, putative AbiEii toxin, Type IV TA system
DGMANHCO_01832 2.5e-182 V ABC transporter
DGMANHCO_01833 7.2e-110 K Transcriptional regulator
DGMANHCO_01834 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
DGMANHCO_01836 2.3e-206 potD P ABC transporter
DGMANHCO_01837 1.2e-141 potC P ABC transporter permease
DGMANHCO_01838 5.5e-147 potB P ABC transporter permease
DGMANHCO_01839 1e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DGMANHCO_01840 2.9e-96 puuR K Cupin domain
DGMANHCO_01841 0.0 yjcE P Sodium proton antiporter
DGMANHCO_01842 2.4e-167 murB 1.3.1.98 M Cell wall formation
DGMANHCO_01843 7.5e-151 xth 3.1.11.2 L exodeoxyribonuclease III
DGMANHCO_01844 2.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
DGMANHCO_01845 3.6e-214 ysdA CP ABC-2 family transporter protein
DGMANHCO_01846 1.8e-167 natA S ABC transporter, ATP-binding protein
DGMANHCO_01848 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
DGMANHCO_01849 6.7e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DGMANHCO_01850 7.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DGMANHCO_01851 3.1e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
DGMANHCO_01852 9e-92 yxjI
DGMANHCO_01853 3.1e-104 3.2.2.20 K Acetyltransferase (GNAT) domain
DGMANHCO_01854 3.5e-194 malK P ATPases associated with a variety of cellular activities
DGMANHCO_01855 1.7e-165 malG P ABC-type sugar transport systems, permease components
DGMANHCO_01856 1.9e-147 malF G Binding-protein-dependent transport system inner membrane component
DGMANHCO_01857 9.8e-231 malE G Bacterial extracellular solute-binding protein
DGMANHCO_01858 7.8e-238 YSH1 S Metallo-beta-lactamase superfamily
DGMANHCO_01859 1.6e-22 ydcG K Helix-turn-helix XRE-family like proteins
DGMANHCO_01860 1.7e-21
DGMANHCO_01861 5.5e-150 malG P ABC transporter permease
DGMANHCO_01862 1.5e-242 malF P Binding-protein-dependent transport system inner membrane component
DGMANHCO_01863 3.2e-223 malE G Bacterial extracellular solute-binding protein
DGMANHCO_01864 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
DGMANHCO_01865 4.3e-211 msmX P Belongs to the ABC transporter superfamily
DGMANHCO_01866 3.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
DGMANHCO_01867 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
DGMANHCO_01868 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
DGMANHCO_01869 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
DGMANHCO_01870 1.3e-176 yvdE K helix_turn _helix lactose operon repressor
DGMANHCO_01871 9.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DGMANHCO_01872 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DGMANHCO_01873 3.8e-139 est 3.1.1.1 S Serine aminopeptidase, S33
DGMANHCO_01874 2.4e-31 secG U Preprotein translocase
DGMANHCO_01875 1.4e-292 clcA P chloride
DGMANHCO_01876 1.1e-47
DGMANHCO_01877 6.7e-229 mdt(A) EGP Major facilitator Superfamily
DGMANHCO_01878 9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DGMANHCO_01879 7.8e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DGMANHCO_01880 4.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DGMANHCO_01881 2.8e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DGMANHCO_01882 1.2e-186 cggR K Putative sugar-binding domain
DGMANHCO_01883 5.5e-63 ligA 2.7.7.7, 6.5.1.2 L EXOIII
DGMANHCO_01885 3.1e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DGMANHCO_01886 6.9e-35 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
DGMANHCO_01887 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
DGMANHCO_01888 6e-239 ydiC1 EGP Major facilitator Superfamily
DGMANHCO_01889 4.7e-73 K helix_turn_helix multiple antibiotic resistance protein
DGMANHCO_01890 2.8e-102
DGMANHCO_01891 2.6e-24
DGMANHCO_01892 3e-240 rarA L recombination factor protein RarA
DGMANHCO_01894 1.1e-38
DGMANHCO_01895 2.9e-82 usp6 T universal stress protein
DGMANHCO_01896 6.1e-152 2.3.1.19 K Helix-turn-helix XRE-family like proteins
DGMANHCO_01897 3.4e-115 yhfA S HAD hydrolase, family IA, variant 3
DGMANHCO_01898 5.8e-180 S Protein of unknown function (DUF2785)
DGMANHCO_01899 2.9e-66 yueI S Protein of unknown function (DUF1694)
DGMANHCO_01900 2.7e-22
DGMANHCO_01901 1.1e-280 sufB O assembly protein SufB
DGMANHCO_01902 1e-78 nifU C SUF system FeS assembly protein, NifU family
DGMANHCO_01903 1e-218 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DGMANHCO_01904 1.1e-189 sufD O FeS assembly protein SufD
DGMANHCO_01905 2.9e-142 sufC O FeS assembly ATPase SufC
DGMANHCO_01906 3.7e-104 metI P ABC transporter permease
DGMANHCO_01907 2.3e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DGMANHCO_01908 2e-149 P Belongs to the nlpA lipoprotein family
DGMANHCO_01909 4e-137 P Belongs to the nlpA lipoprotein family
DGMANHCO_01910 7.5e-222 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
DGMANHCO_01911 9.5e-49 gcvH E glycine cleavage
DGMANHCO_01912 5.3e-223 rodA D Belongs to the SEDS family
DGMANHCO_01913 1.1e-30 S Protein of unknown function (DUF2969)
DGMANHCO_01914 9.1e-55 yidD S Could be involved in insertion of integral membrane proteins into the membrane
DGMANHCO_01915 2.2e-18 epuA S DNA-directed RNA polymerase subunit beta
DGMANHCO_01916 9.4e-178 mbl D Cell shape determining protein MreB Mrl
DGMANHCO_01917 4.2e-31 ywzB S Protein of unknown function (DUF1146)
DGMANHCO_01918 8.3e-70 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DGMANHCO_01919 1.3e-244 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DGMANHCO_01920 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DGMANHCO_01921 9.5e-286 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DGMANHCO_01922 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DGMANHCO_01923 8.6e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DGMANHCO_01924 3.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DGMANHCO_01925 7.9e-126 atpB C it plays a direct role in the translocation of protons across the membrane
DGMANHCO_01926 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DGMANHCO_01927 4.4e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DGMANHCO_01928 3.1e-184 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DGMANHCO_01929 5.7e-152 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DGMANHCO_01930 5.6e-176 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DGMANHCO_01931 1.3e-110 tdk 2.7.1.21 F thymidine kinase
DGMANHCO_01932 2.5e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
DGMANHCO_01933 3.5e-196 ampC V Beta-lactamase
DGMANHCO_01934 2e-163 1.13.11.2 S glyoxalase
DGMANHCO_01935 3.9e-139 S NADPH-dependent FMN reductase
DGMANHCO_01936 0.0 yfiC V ABC transporter
DGMANHCO_01937 0.0 ycfI V ABC transporter, ATP-binding protein
DGMANHCO_01938 2.2e-119 K Bacterial regulatory proteins, tetR family
DGMANHCO_01939 7.2e-127 G Phosphoglycerate mutase family
DGMANHCO_01940 1.6e-07
DGMANHCO_01942 1.2e-285 pipD E Dipeptidase
DGMANHCO_01943 1.4e-104 S Protein of unknown function (DUF1211)
DGMANHCO_01944 3.9e-210 yttB EGP Major facilitator Superfamily
DGMANHCO_01945 3.2e-13
DGMANHCO_01946 1.1e-78 tspO T TspO/MBR family
DGMANHCO_01949 2.9e-78 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
DGMANHCO_01950 1e-173 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
DGMANHCO_01951 6.6e-231 wbbX GT2,GT4 M Glycosyl transferases group 1
DGMANHCO_01952 3e-43 yttA 2.7.13.3 S Pfam Transposase IS66
DGMANHCO_01953 1.6e-149 F DNA/RNA non-specific endonuclease
DGMANHCO_01955 8.6e-47 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
DGMANHCO_01956 1.3e-134 S Domain of unknown function DUF1829
DGMANHCO_01957 5.6e-258 pgi 5.3.1.9 G Belongs to the GPI family
DGMANHCO_01958 5.9e-152 glcU U sugar transport
DGMANHCO_01959 1.4e-110 vanZ V VanZ like family
DGMANHCO_01960 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DGMANHCO_01961 5.2e-104
DGMANHCO_01962 8e-105
DGMANHCO_01963 1.8e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DGMANHCO_01964 1.9e-203 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DGMANHCO_01965 8.9e-240 pbuX F xanthine permease
DGMANHCO_01966 1.4e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DGMANHCO_01967 1.9e-115 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
DGMANHCO_01968 1.2e-82 yvbK 3.1.3.25 K GNAT family
DGMANHCO_01969 7.9e-31 cspC K Cold shock protein
DGMANHCO_01970 6.6e-168 yqjA S Putative aromatic acid exporter C-terminal domain
DGMANHCO_01971 2.7e-77
DGMANHCO_01972 6.2e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
DGMANHCO_01973 0.0 S Psort location CytoplasmicMembrane, score
DGMANHCO_01974 2.6e-65 nrp 1.20.4.1 P ArsC family
DGMANHCO_01975 0.0 clpL O associated with various cellular activities
DGMANHCO_01976 3.1e-144 ywqE 3.1.3.48 GM PHP domain protein
DGMANHCO_01977 5.4e-156 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DGMANHCO_01978 0.0 kup P Transport of potassium into the cell
DGMANHCO_01979 8.7e-167 V ATPases associated with a variety of cellular activities
DGMANHCO_01980 1.9e-217 S ABC-2 family transporter protein
DGMANHCO_01981 1.7e-196
DGMANHCO_01983 9e-130 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
DGMANHCO_01984 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
DGMANHCO_01985 2e-97
DGMANHCO_01986 2.3e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
DGMANHCO_01987 1.8e-55 K Helix-turn-helix XRE-family like proteins
DGMANHCO_01988 4.3e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
DGMANHCO_01989 3.1e-225 queG 1.17.99.6 C Domain of unknown function (DUF1730)
DGMANHCO_01990 1.4e-62
DGMANHCO_01991 7.1e-87 bioY S BioY family
DGMANHCO_01992 3.5e-70 adhR K helix_turn_helix, mercury resistance
DGMANHCO_01993 2.3e-125 WQ51_05710 S Mitochondrial biogenesis AIM24
DGMANHCO_01994 3e-71 FG Scavenger mRNA decapping enzyme C-term binding
DGMANHCO_01995 0.0 asnB 6.3.5.4 E Asparagine synthase
DGMANHCO_01997 5e-134 S ABC-2 family transporter protein
DGMANHCO_01998 1.4e-133 S ABC transporter
DGMANHCO_01999 3.9e-26 S Protein of unknown function (DUF2785)
DGMANHCO_02000 7.7e-100
DGMANHCO_02001 1.6e-52
DGMANHCO_02002 0.0 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
DGMANHCO_02003 4.4e-104 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
DGMANHCO_02004 1e-182 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
DGMANHCO_02005 2e-238 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
DGMANHCO_02006 1.5e-17
DGMANHCO_02008 1.6e-126 K Transcriptional regulatory protein, C terminal
DGMANHCO_02009 1e-238 T PhoQ Sensor
DGMANHCO_02010 8e-117 dedA S SNARE-like domain protein
DGMANHCO_02011 1.4e-119 lssY 3.6.1.27 I phosphatase
DGMANHCO_02012 1.2e-169 ykoT GT2 M Glycosyl transferase family 2
DGMANHCO_02013 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DGMANHCO_02014 3.4e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DGMANHCO_02015 3.5e-117 alkD L DNA alkylation repair enzyme
DGMANHCO_02016 1.5e-194 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
DGMANHCO_02017 1.8e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
DGMANHCO_02018 4.8e-151 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DGMANHCO_02019 7.3e-163 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DGMANHCO_02020 5.1e-139 K Bacterial transcriptional regulator
DGMANHCO_02021 4.5e-157 Z012_03480 S Psort location Cytoplasmic, score
DGMANHCO_02022 2e-235 ugl 3.2.1.180 GH88 S Glycosyl Hydrolase Family 88
DGMANHCO_02023 1.2e-88 agaV 2.7.1.191 G PTS system sorbose subfamily IIB component
DGMANHCO_02024 4.3e-144 G PTS system sorbose-specific iic component
DGMANHCO_02025 5.6e-144 agaD G PTS system mannose/fructose/sorbose family IID component
DGMANHCO_02026 5.1e-81 G PTS system fructose IIA component
DGMANHCO_02028 0.0 M Heparinase II/III N-terminus
DGMANHCO_02029 8.5e-62
DGMANHCO_02030 1.1e-293 plyA3 M Right handed beta helix region
DGMANHCO_02032 1.9e-132 L Transposase, IS116 IS110 IS902 family
DGMANHCO_02033 1.2e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DGMANHCO_02034 2.8e-129 rpl K Helix-turn-helix domain, rpiR family
DGMANHCO_02035 3.3e-172 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
DGMANHCO_02036 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DGMANHCO_02037 2.5e-88
DGMANHCO_02038 2e-118 ydfK S Protein of unknown function (DUF554)
DGMANHCO_02039 4.9e-181 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DGMANHCO_02040 1.3e-226 EK Aminotransferase, class I
DGMANHCO_02041 1.7e-165 K LysR substrate binding domain
DGMANHCO_02042 9.8e-88 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DGMANHCO_02043 4.3e-152 yitU 3.1.3.104 S hydrolase
DGMANHCO_02044 6.4e-125 yjhF G Phosphoglycerate mutase family
DGMANHCO_02045 6.2e-104 yoaK S Protein of unknown function (DUF1275)
DGMANHCO_02046 4.1e-11
DGMANHCO_02047 8.1e-60
DGMANHCO_02048 7.3e-144 S hydrolase
DGMANHCO_02049 8.1e-193 yghZ C Aldo keto reductase family protein
DGMANHCO_02050 0.0 uvrA3 L excinuclease ABC
DGMANHCO_02051 4e-69 K MarR family
DGMANHCO_02052 1.1e-115 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
DGMANHCO_02054 2.8e-114 S CAAX protease self-immunity
DGMANHCO_02055 4.5e-172 shetA P Voltage-dependent anion channel
DGMANHCO_02056 8.6e-148 rlrG K Transcriptional regulator
DGMANHCO_02057 0.0 helD 3.6.4.12 L DNA helicase
DGMANHCO_02060 1.2e-62
DGMANHCO_02061 9.9e-62 S MucBP domain
DGMANHCO_02062 2.1e-102 ywnB S NAD(P)H-binding
DGMANHCO_02065 1.1e-122 E lipolytic protein G-D-S-L family
DGMANHCO_02066 9.4e-70 feoA P FeoA
DGMANHCO_02067 9.5e-22 feoB P transporter of a GTP-driven Fe(2 ) uptake system
DGMANHCO_02068 6.2e-103
DGMANHCO_02069 3.1e-105 S Membrane
DGMANHCO_02070 1.3e-284 pipD E Dipeptidase
DGMANHCO_02072 2.3e-102 yncA 2.3.1.79 S Maltose acetyltransferase
DGMANHCO_02073 3.8e-54 S Enterocin A Immunity
DGMANHCO_02075 2.9e-54
DGMANHCO_02077 1e-142 S CAAX protease self-immunity
DGMANHCO_02078 3.6e-82 C Flavodoxin
DGMANHCO_02079 8.1e-196 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
DGMANHCO_02080 4.9e-114 GM NmrA-like family
DGMANHCO_02082 5.8e-100 Q methyltransferase
DGMANHCO_02083 3.4e-90 T Sh3 type 3 domain protein
DGMANHCO_02084 6.2e-119 yfeJ 6.3.5.2 F glutamine amidotransferase
DGMANHCO_02085 1.2e-132 S Uncharacterized protein conserved in bacteria (DUF2263)
DGMANHCO_02086 5.3e-259 yhdP S Transporter associated domain
DGMANHCO_02087 1e-257 lmrB EGP Major facilitator Superfamily
DGMANHCO_02088 2.8e-61 S Domain of unknown function (DUF4811)
DGMANHCO_02089 1.1e-98 maf D nucleoside-triphosphate diphosphatase activity
DGMANHCO_02090 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DGMANHCO_02091 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DGMANHCO_02092 0.0 ydaO E amino acid
DGMANHCO_02093 2.4e-56 S Domain of unknown function (DUF1827)
DGMANHCO_02094 1e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DGMANHCO_02095 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DGMANHCO_02096 1.9e-110 S CAAX protease self-immunity
DGMANHCO_02097 2.4e-195 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DGMANHCO_02098 1.8e-184
DGMANHCO_02099 2.6e-158 ytrB V ABC transporter
DGMANHCO_02100 2.7e-61 ytrA K helix_turn_helix gluconate operon transcriptional repressor
DGMANHCO_02101 7.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DGMANHCO_02102 0.0 uup S ABC transporter, ATP-binding protein
DGMANHCO_02103 3.9e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
DGMANHCO_02104 4.2e-189 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DGMANHCO_02105 3.6e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
DGMANHCO_02106 5.3e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
DGMANHCO_02107 4.6e-74
DGMANHCO_02108 3.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
DGMANHCO_02109 2e-180 ansA 3.5.1.1 EJ Asparaginase
DGMANHCO_02110 8.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
DGMANHCO_02111 2.2e-143 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DGMANHCO_02112 2.2e-57 yabA L Involved in initiation control of chromosome replication
DGMANHCO_02113 5.8e-172 holB 2.7.7.7 L DNA polymerase III
DGMANHCO_02114 4.6e-52 yaaQ S Cyclic-di-AMP receptor
DGMANHCO_02115 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DGMANHCO_02116 5.8e-34 S Protein of unknown function (DUF2508)
DGMANHCO_02117 4.8e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DGMANHCO_02118 8.4e-32 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DGMANHCO_02119 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DGMANHCO_02120 2.5e-89 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DGMANHCO_02121 5.6e-50
DGMANHCO_02122 5.3e-107 rsmC 2.1.1.172 J Methyltransferase
DGMANHCO_02123 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DGMANHCO_02124 1.8e-45
DGMANHCO_02125 2.2e-176 ccpB 5.1.1.1 K lacI family
DGMANHCO_02126 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
DGMANHCO_02127 1.6e-155 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DGMANHCO_02128 3.1e-133 glnQ E ABC transporter, ATP-binding protein
DGMANHCO_02129 9e-287 glnP P ABC transporter permease
DGMANHCO_02131 9.6e-158 K Helix-turn-helix XRE-family like proteins
DGMANHCO_02132 2.5e-150 K Helix-turn-helix XRE-family like proteins
DGMANHCO_02133 6.7e-187 K Helix-turn-helix XRE-family like proteins
DGMANHCO_02134 4.5e-217 EGP Major facilitator Superfamily
DGMANHCO_02135 1.4e-181 manL 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
DGMANHCO_02136 1.9e-120 manY G PTS system
DGMANHCO_02137 9.6e-169 manN G system, mannose fructose sorbose family IID component
DGMANHCO_02138 3.4e-64 manO S Domain of unknown function (DUF956)
DGMANHCO_02139 1.6e-171 iolS C Aldo keto reductase
DGMANHCO_02140 2.2e-213 yeaN P Transporter, major facilitator family protein
DGMANHCO_02141 7.8e-242 ydiC1 EGP Major Facilitator Superfamily
DGMANHCO_02142 2.3e-113 ycaC Q Isochorismatase family
DGMANHCO_02143 1.9e-89 S AAA domain
DGMANHCO_02144 1.7e-84 F NUDIX domain
DGMANHCO_02145 1.2e-105 speG J Acetyltransferase (GNAT) domain
DGMANHCO_02146 2.4e-53 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
DGMANHCO_02147 2.3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
DGMANHCO_02148 1.5e-129 K UTRA
DGMANHCO_02149 3.6e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DGMANHCO_02150 4.6e-73 S Domain of unknown function (DUF3284)
DGMANHCO_02151 3.1e-214 S Bacterial protein of unknown function (DUF871)
DGMANHCO_02152 2.4e-264 argH 4.3.2.1 E argininosuccinate lyase
DGMANHCO_02153 3.7e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DGMANHCO_02154 3.5e-258 arpJ P ABC transporter permease
DGMANHCO_02155 1.5e-121 3.1.1.24 S Alpha/beta hydrolase family
DGMANHCO_02156 8.1e-131 K response regulator
DGMANHCO_02157 0.0 vicK 2.7.13.3 T Histidine kinase
DGMANHCO_02158 1.1e-254 yycH S YycH protein
DGMANHCO_02159 3.1e-139 yycI S YycH protein
DGMANHCO_02160 1.2e-154 vicX 3.1.26.11 S domain protein
DGMANHCO_02161 4.3e-210 htrA 3.4.21.107 O serine protease
DGMANHCO_02162 4.1e-71 S Iron-sulphur cluster biosynthesis
DGMANHCO_02163 2.3e-75 hsp3 O Belongs to the small heat shock protein (HSP20) family
DGMANHCO_02164 0.0 cadA P P-type ATPase
DGMANHCO_02165 1e-101
DGMANHCO_02166 1.3e-298 E ABC transporter, substratebinding protein
DGMANHCO_02167 7.6e-255 E Peptidase dimerisation domain
DGMANHCO_02168 2.1e-69
DGMANHCO_02169 4.1e-198 ybiR P Citrate transporter
DGMANHCO_02170 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DGMANHCO_02171 1.2e-74 2.3.1.82 K Acetyltransferase (GNAT) domain
DGMANHCO_02172 9e-83 yiaC K Acetyltransferase (GNAT) domain
DGMANHCO_02173 4.5e-86 K Acetyltransferase (GNAT) domain
DGMANHCO_02174 8.6e-139 wzb 3.1.3.48 T Tyrosine phosphatase family
DGMANHCO_02175 1.7e-54 1.1.1.1 C nadph quinone reductase
DGMANHCO_02176 2.3e-125 1.1.1.1 C nadph quinone reductase
DGMANHCO_02177 6.4e-93 hisB 2.7.7.71, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 5.3.1.28, 6.3.2.10 GT9 E HAD-hyrolase-like
DGMANHCO_02178 4.7e-93 MA20_25245 K FR47-like protein
DGMANHCO_02179 9.5e-135 S -acetyltransferase
DGMANHCO_02180 4.4e-52 sugE U Multidrug resistance protein
DGMANHCO_02181 2e-88 Q Methyltransferase
DGMANHCO_02182 1.2e-68 lctO C IMP dehydrogenase / GMP reductase domain
DGMANHCO_02183 1.1e-121 drgA C Nitroreductase family
DGMANHCO_02184 1.4e-158 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
DGMANHCO_02185 1.4e-161 ptlF S KR domain
DGMANHCO_02186 1.4e-165 QT PucR C-terminal helix-turn-helix domain
DGMANHCO_02187 1.4e-92 QT PucR C-terminal helix-turn-helix domain
DGMANHCO_02188 3.1e-68 yqkB S Belongs to the HesB IscA family
DGMANHCO_02189 2.7e-241 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
DGMANHCO_02190 5.3e-124 K cheY-homologous receiver domain
DGMANHCO_02191 4.1e-71 S GtrA-like protein
DGMANHCO_02192 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
DGMANHCO_02193 6.2e-182 ykcC GT2 M Glycosyl transferase family 2
DGMANHCO_02194 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
DGMANHCO_02195 8e-174 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
DGMANHCO_02196 8.8e-142 cmpC S ABC transporter, ATP-binding protein
DGMANHCO_02197 1.9e-154 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
DGMANHCO_02198 3.1e-165 XK27_00670 S ABC transporter
DGMANHCO_02199 6.1e-166 XK27_00670 S ABC transporter substrate binding protein
DGMANHCO_02200 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
DGMANHCO_02201 1.5e-115 ywnB S NAD(P)H-binding
DGMANHCO_02202 3.9e-07
DGMANHCO_02203 1.4e-195
DGMANHCO_02204 1.6e-154 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DGMANHCO_02205 4.1e-118 S Psort location Cytoplasmic, score
DGMANHCO_02206 1.5e-86 S Short repeat of unknown function (DUF308)
DGMANHCO_02208 2.1e-120 yrkL S Flavodoxin-like fold
DGMANHCO_02209 2.5e-149 cytC6 I alpha/beta hydrolase fold
DGMANHCO_02210 9.6e-208 mutY L A G-specific adenine glycosylase
DGMANHCO_02212 2.2e-76 hsp1 O Belongs to the small heat shock protein (HSP20) family
DGMANHCO_02213 2.1e-14
DGMANHCO_02214 0.0 sbcC L Putative exonuclease SbcCD, C subunit
DGMANHCO_02215 6.2e-210 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DGMANHCO_02216 3.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
DGMANHCO_02217 4.2e-141 lacR K DeoR C terminal sensor domain
DGMANHCO_02218 2.7e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
DGMANHCO_02219 2.9e-93 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
DGMANHCO_02220 2.5e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
DGMANHCO_02221 4.9e-176 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
DGMANHCO_02222 4.6e-123 S Domain of unknown function (DUF4867)
DGMANHCO_02223 5.6e-26
DGMANHCO_02224 1.6e-266 gatC G PTS system sugar-specific permease component
DGMANHCO_02225 1.4e-50 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
DGMANHCO_02226 2.1e-85 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DGMANHCO_02229 7.6e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
DGMANHCO_02230 8.6e-163 K Transcriptional regulator
DGMANHCO_02231 2.5e-280 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DGMANHCO_02232 3.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DGMANHCO_02233 2.8e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DGMANHCO_02234 2.6e-92 ccpN K Domain in cystathionine beta-synthase and other proteins.
DGMANHCO_02235 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
DGMANHCO_02236 9.3e-261 pepC 3.4.22.40 E Peptidase C1-like family
DGMANHCO_02237 3.6e-257 pepC 3.4.22.40 E aminopeptidase
DGMANHCO_02238 9.5e-70 S Protein of unknown function (DUF805)
DGMANHCO_02239 2.9e-50 HA62_12640 S GCN5-related N-acetyl-transferase
DGMANHCO_02240 9.6e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
DGMANHCO_02241 6.5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DGMANHCO_02242 1.2e-202 yacL S domain protein
DGMANHCO_02243 1.7e-216 inlJ M MucBP domain
DGMANHCO_02244 8e-61 K helix_turn_helix gluconate operon transcriptional repressor
DGMANHCO_02245 6.9e-176 S Membrane
DGMANHCO_02246 6.9e-113 yhfC S Putative membrane peptidase family (DUF2324)
DGMANHCO_02247 9.1e-142 K SIS domain
DGMANHCO_02248 2.3e-76 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
DGMANHCO_02249 4.3e-183 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
DGMANHCO_02250 6.2e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DGMANHCO_02252 2.3e-107
DGMANHCO_02253 1.6e-260 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
DGMANHCO_02254 1.4e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DGMANHCO_02255 8.5e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DGMANHCO_02256 1.4e-139 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DGMANHCO_02257 2.4e-98 yacP S YacP-like NYN domain
DGMANHCO_02259 5.7e-189 XK27_00915 C Luciferase-like monooxygenase
DGMANHCO_02260 7e-93 1.5.1.40 S Rossmann-like domain
DGMANHCO_02263 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DGMANHCO_02264 1.2e-98 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
DGMANHCO_02265 1.2e-79 ynhH S NusG domain II
DGMANHCO_02266 0.0 ndh 1.6.99.3 C NADH dehydrogenase
DGMANHCO_02267 1.2e-137 cad S FMN_bind
DGMANHCO_02268 4.4e-197 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DGMANHCO_02269 1.1e-167 menA 2.5.1.74 M UbiA prenyltransferase family
DGMANHCO_02270 2e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
DGMANHCO_02271 1.6e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DGMANHCO_02272 3.4e-100 nusG K Participates in transcription elongation, termination and antitermination
DGMANHCO_02273 3.8e-159 S Alpha/beta hydrolase of unknown function (DUF915)
DGMANHCO_02274 1.4e-77 F Nucleoside 2-deoxyribosyltransferase
DGMANHCO_02275 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
DGMANHCO_02276 2e-62 S Domain of unknown function (DUF4430)
DGMANHCO_02277 3.2e-93 S ECF transporter, substrate-specific component
DGMANHCO_02278 1.5e-92 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
DGMANHCO_02279 1.1e-65 frataxin S Domain of unknown function (DU1801)
DGMANHCO_02280 7.7e-269 nylA 3.5.1.4 J Belongs to the amidase family
DGMANHCO_02281 0.0 mgtA 3.6.3.2, 3.6.3.6 P COG0474 Cation transport ATPase
DGMANHCO_02282 8.2e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DGMANHCO_02283 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DGMANHCO_02284 2.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
DGMANHCO_02285 1.9e-217 yceI G Sugar (and other) transporter
DGMANHCO_02286 3.1e-66
DGMANHCO_02287 1.6e-154 K acetyltransferase
DGMANHCO_02288 5e-221 mdtG EGP Major facilitator Superfamily
DGMANHCO_02289 6.5e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DGMANHCO_02290 1.1e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DGMANHCO_02291 7.5e-169 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
DGMANHCO_02292 1.5e-98 S ABC-2 family transporter protein
DGMANHCO_02293 4.8e-157 K Transcriptional regulator
DGMANHCO_02294 1.8e-77 yphH S Cupin domain
DGMANHCO_02295 3.2e-55 yphJ 4.1.1.44 S decarboxylase
DGMANHCO_02296 1.4e-58 P ABC-2 family transporter protein
DGMANHCO_02297 1.5e-10 V ABC-2 type transporter
DGMANHCO_02298 7.7e-60 V ABC-2 type transporter
DGMANHCO_02299 4e-68 K Tetracyclin repressor, C-terminal all-alpha domain
DGMANHCO_02301 1.9e-47 V ATPases associated with a variety of cellular activities
DGMANHCO_02302 9.2e-253 gshR 1.8.1.7 C Glutathione reductase
DGMANHCO_02303 1.7e-176 proV E ABC transporter, ATP-binding protein
DGMANHCO_02304 6.5e-179 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
DGMANHCO_02305 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
DGMANHCO_02306 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DGMANHCO_02307 1.9e-107 K Bacterial regulatory proteins, tetR family
DGMANHCO_02308 2.1e-183 yxeA V FtsX-like permease family
DGMANHCO_02309 4.6e-126 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
DGMANHCO_02310 1.1e-33
DGMANHCO_02311 1.3e-110 tipA K TipAS antibiotic-recognition domain
DGMANHCO_02312 1.1e-20 M1-1017
DGMANHCO_02313 8.2e-33 K Transcriptional regulator PadR-like family
DGMANHCO_02314 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DGMANHCO_02315 8.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DGMANHCO_02316 6e-157 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DGMANHCO_02317 1.6e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DGMANHCO_02318 4.5e-115
DGMANHCO_02319 4.8e-61 rplQ J Ribosomal protein L17
DGMANHCO_02320 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DGMANHCO_02321 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DGMANHCO_02322 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DGMANHCO_02323 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DGMANHCO_02324 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DGMANHCO_02325 4.6e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DGMANHCO_02326 2e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DGMANHCO_02327 6.5e-62 rplO J Binds to the 23S rRNA
DGMANHCO_02328 3.9e-24 rpmD J Ribosomal protein L30
DGMANHCO_02329 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DGMANHCO_02330 1.8e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DGMANHCO_02331 1.7e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DGMANHCO_02332 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DGMANHCO_02333 8.5e-96 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DGMANHCO_02334 6.9e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DGMANHCO_02335 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DGMANHCO_02336 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DGMANHCO_02337 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
DGMANHCO_02338 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DGMANHCO_02339 6.2e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DGMANHCO_02340 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DGMANHCO_02341 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DGMANHCO_02342 2.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DGMANHCO_02343 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DGMANHCO_02344 1.7e-108 rplD J Forms part of the polypeptide exit tunnel
DGMANHCO_02345 4e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DGMANHCO_02346 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
DGMANHCO_02347 3.5e-68 psiE S Phosphate-starvation-inducible E
DGMANHCO_02348 1.9e-106 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
DGMANHCO_02349 1e-198 yfjR K WYL domain
DGMANHCO_02350 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DGMANHCO_02351 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DGMANHCO_02352 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DGMANHCO_02353 0.0 M domain protein
DGMANHCO_02354 0.0 M domain protein
DGMANHCO_02355 3.1e-36 3.4.23.43
DGMANHCO_02356 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DGMANHCO_02357 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DGMANHCO_02358 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DGMANHCO_02359 4.3e-80 ctsR K Belongs to the CtsR family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)