ORF_ID e_value Gene_name EC_number CAZy COGs Description
PKNEJCON_00002 1.1e-158 S CHAP domain
PKNEJCON_00003 2.8e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PKNEJCON_00004 2.2e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PKNEJCON_00005 2.1e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PKNEJCON_00006 5.1e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PKNEJCON_00007 2.8e-44 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PKNEJCON_00008 1.2e-103 magIII L Base excision DNA repair protein, HhH-GPD family
PKNEJCON_00009 2.1e-261 proWX P ABC transporter
PKNEJCON_00010 6.6e-128 proV E abc transporter atp-binding protein
PKNEJCON_00011 7e-145 1.6.5.2 GM epimerase
PKNEJCON_00012 2.1e-68 mgrA K Transcriptional regulator, MarR family
PKNEJCON_00013 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PKNEJCON_00014 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PKNEJCON_00017 0.0 mdlB V abc transporter atp-binding protein
PKNEJCON_00018 0.0 mdlA V abc transporter atp-binding protein
PKNEJCON_00021 3.8e-85 XK27_09885 V Glycopeptide antibiotics resistance protein
PKNEJCON_00022 6.7e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PKNEJCON_00023 1.8e-61 yutD J protein conserved in bacteria
PKNEJCON_00024 5.9e-258 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PKNEJCON_00025 1.1e-34 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PKNEJCON_00026 2.9e-51 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PKNEJCON_00027 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PKNEJCON_00028 2.9e-22 WQ51_00220 K Helix-turn-helix domain
PKNEJCON_00029 2.2e-91 S Protein of unknown function (DUF3278)
PKNEJCON_00030 2.8e-130 smc D Required for chromosome condensation and partitioning
PKNEJCON_00031 7.6e-266 smc D Required for chromosome condensation and partitioning
PKNEJCON_00032 1.1e-80 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PKNEJCON_00033 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PKNEJCON_00035 1.2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
PKNEJCON_00036 1.4e-237 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PKNEJCON_00038 6.3e-85 S ECF-type riboflavin transporter, S component
PKNEJCON_00039 2.6e-152 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
PKNEJCON_00040 3.4e-81 XK27_01265 S ECF-type riboflavin transporter, S component
PKNEJCON_00041 3.5e-230 S COG1073 Hydrolases of the alpha beta superfamily
PKNEJCON_00042 6.5e-73 K transcriptional
PKNEJCON_00043 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PKNEJCON_00044 4.2e-133 glcR K transcriptional regulator (DeoR family)
PKNEJCON_00045 1.7e-145 cof S Sucrose-6F-phosphate phosphohydrolase
PKNEJCON_00046 9e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
PKNEJCON_00047 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
PKNEJCON_00048 0.0 casA L An automated process has identified a potential problem with this gene model
PKNEJCON_00049 0.0 cas3 L CRISPR-associated helicase cas3
PKNEJCON_00050 0.0 S the current gene model (or a revised gene model) may contain a frame shift
PKNEJCON_00051 1.1e-77 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PKNEJCON_00052 0.0 3.5.1.28 NU amidase activity
PKNEJCON_00053 8e-288 lpdA 1.8.1.4 C Dehydrogenase
PKNEJCON_00054 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PKNEJCON_00056 8.2e-137 IQ Acetoin reductase
PKNEJCON_00057 1.2e-43 pspE P Rhodanese-like protein
PKNEJCON_00058 8.5e-72 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PKNEJCON_00059 2.9e-223 XK27_05470 E Methionine synthase
PKNEJCON_00060 4e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PKNEJCON_00061 6.3e-48 T PhoQ Sensor
PKNEJCON_00062 7.8e-35 rpsF J Binds together with S18 to 16S ribosomal RNA
PKNEJCON_00063 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PKNEJCON_00064 1.8e-34 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PKNEJCON_00066 1.9e-121 XK27_01040 S Protein of unknown function (DUF1129)
PKNEJCON_00067 2.2e-168 corA P COG0598 Mg2 and Co2 transporters
PKNEJCON_00068 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PKNEJCON_00072 2.8e-32 blpT
PKNEJCON_00073 5.9e-186 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
PKNEJCON_00074 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
PKNEJCON_00075 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PKNEJCON_00076 1.7e-61 yqhY S protein conserved in bacteria
PKNEJCON_00077 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PKNEJCON_00078 9.2e-178 scrR K Transcriptional regulator
PKNEJCON_00079 7.8e-290 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
PKNEJCON_00080 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PKNEJCON_00081 1.6e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
PKNEJCON_00082 1.9e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
PKNEJCON_00084 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PKNEJCON_00085 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PKNEJCON_00086 1.4e-195 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PKNEJCON_00087 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PKNEJCON_00088 3.5e-181 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PKNEJCON_00089 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PKNEJCON_00093 2.9e-31 yozG K Transcriptional regulator
PKNEJCON_00095 4e-170 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PKNEJCON_00096 3.2e-256 XK27_03190 S hydrolases of the HAD superfamily
PKNEJCON_00097 7.7e-110 yebC M Membrane
PKNEJCON_00098 1.8e-309 KT response to antibiotic
PKNEJCON_00099 1.5e-74 XK27_02470 K LytTr DNA-binding domain
PKNEJCON_00100 1.1e-119 liaI S membrane
PKNEJCON_00106 7.9e-59
PKNEJCON_00110 7.2e-246 S DNA primase
PKNEJCON_00111 4.9e-138 KL Phage plasmid primase P4 family
PKNEJCON_00112 2.6e-13
PKNEJCON_00114 2.7e-23
PKNEJCON_00115 4.3e-07
PKNEJCON_00116 2.3e-13
PKNEJCON_00117 4.7e-72 K transcriptional
PKNEJCON_00118 1.6e-197 sip L Belongs to the 'phage' integrase family
PKNEJCON_00119 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PKNEJCON_00120 3.1e-75 yueI S Protein of unknown function (DUF1694)
PKNEJCON_00121 9.3e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PKNEJCON_00122 3.6e-199 yyaQ S YjbR
PKNEJCON_00123 2.4e-181 ccpA K Catabolite control protein A
PKNEJCON_00124 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
PKNEJCON_00125 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
PKNEJCON_00126 8.2e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PKNEJCON_00127 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PKNEJCON_00128 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PKNEJCON_00129 2e-33 secG U Preprotein translocase subunit SecG
PKNEJCON_00130 1.3e-221 mdtG EGP Major facilitator Superfamily
PKNEJCON_00131 3.4e-90 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PKNEJCON_00132 3.7e-151 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PKNEJCON_00133 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PKNEJCON_00134 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PKNEJCON_00135 3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PKNEJCON_00136 2.1e-149 licT K antiterminator
PKNEJCON_00137 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PKNEJCON_00138 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
PKNEJCON_00139 1.2e-146 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PKNEJCON_00140 6.9e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PKNEJCON_00141 1.3e-150 I Alpha/beta hydrolase family
PKNEJCON_00142 6.6e-08
PKNEJCON_00143 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PKNEJCON_00144 9.1e-78 feoA P FeoA domain protein
PKNEJCON_00145 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
PKNEJCON_00146 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
PKNEJCON_00147 1e-34 ykuJ S protein conserved in bacteria
PKNEJCON_00148 3.7e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PKNEJCON_00149 0.0 clpE O Belongs to the ClpA ClpB family
PKNEJCON_00150 7.4e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PKNEJCON_00151 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
PKNEJCON_00152 2.6e-172 S oxidoreductase
PKNEJCON_00153 5e-229 murN 2.3.2.16 V FemAB family
PKNEJCON_00154 1.4e-116 M Pfam SNARE associated Golgi protein
PKNEJCON_00155 2.5e-107 S Domain of Unknown Function with PDB structure (DUF3862)
PKNEJCON_00158 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
PKNEJCON_00161 4.8e-16 S Protein of unknown function (DUF2969)
PKNEJCON_00162 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
PKNEJCON_00163 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PKNEJCON_00164 3.1e-10
PKNEJCON_00166 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PKNEJCON_00167 2.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PKNEJCON_00168 2.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
PKNEJCON_00169 2.2e-30 S Domain of unknown function (DUF1912)
PKNEJCON_00170 4.7e-166 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
PKNEJCON_00171 5.4e-248 mmuP E amino acid
PKNEJCON_00172 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PKNEJCON_00173 4.4e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PKNEJCON_00174 9.7e-22
PKNEJCON_00175 1.3e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PKNEJCON_00176 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PKNEJCON_00177 1.9e-209 mvaS 2.3.3.10 I synthase
PKNEJCON_00178 4.5e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PKNEJCON_00179 4.7e-76 K hmm pf08876
PKNEJCON_00180 1.2e-118 yqfA K protein, Hemolysin III
PKNEJCON_00181 4.1e-29 pspC KT PspC domain protein
PKNEJCON_00182 1.4e-190 S Protein of unknown function (DUF3114)
PKNEJCON_00183 9.6e-148 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PKNEJCON_00184 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PKNEJCON_00185 4.4e-07
PKNEJCON_00186 9.8e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PKNEJCON_00187 1.5e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
PKNEJCON_00188 0.0 U protein secretion
PKNEJCON_00189 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PKNEJCON_00190 1.9e-24
PKNEJCON_00191 5.9e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
PKNEJCON_00192 3.2e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PKNEJCON_00193 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
PKNEJCON_00194 2.8e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
PKNEJCON_00195 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PKNEJCON_00196 5.9e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PKNEJCON_00197 5.9e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PKNEJCON_00198 7.2e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
PKNEJCON_00199 8.3e-87 ykuL S CBS domain
PKNEJCON_00200 5.1e-98 XK27_09740 S Phosphoesterase
PKNEJCON_00201 3.6e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PKNEJCON_00202 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PKNEJCON_00203 1.6e-36 yneF S UPF0154 protein
PKNEJCON_00204 1.8e-90 K transcriptional regulator
PKNEJCON_00205 8.9e-176 XK27_08835 S ABC transporter substrate binding protein
PKNEJCON_00206 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
PKNEJCON_00207 3.1e-136 XK27_08845 S abc transporter atp-binding protein
PKNEJCON_00208 4.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PKNEJCON_00209 2.8e-148 estA CE1 S Esterase
PKNEJCON_00210 1.5e-124 XK27_08875 O Zinc-dependent metalloprotease
PKNEJCON_00211 9.5e-186 nss M transferase activity, transferring glycosyl groups
PKNEJCON_00212 1.4e-15 S Accessory secretory protein Sec, Asp5
PKNEJCON_00213 2.6e-17 S Accessory secretory protein Sec Asp4
PKNEJCON_00214 3.9e-243 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PKNEJCON_00215 4.1e-153 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PKNEJCON_00216 3.2e-223 thrE K Psort location CytoplasmicMembrane, score
PKNEJCON_00217 3.6e-177 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
PKNEJCON_00218 2.6e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
PKNEJCON_00219 6.3e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
PKNEJCON_00220 4.7e-177 XK27_10475 S oxidoreductase
PKNEJCON_00221 3.2e-195 gldA 1.1.1.6 C glycerol dehydrogenase
PKNEJCON_00223 8.6e-284 XK27_07020 S Belongs to the UPF0371 family
PKNEJCON_00224 3.3e-212 vex1 V Efflux ABC transporter, permease protein
PKNEJCON_00225 1.9e-107 vex2 V abc transporter atp-binding protein
PKNEJCON_00226 4.6e-239 vex3 V Efflux ABC transporter, permease protein
PKNEJCON_00227 4.4e-115 K Response regulator receiver domain protein
PKNEJCON_00228 2.6e-220 vncS 2.7.13.3 T Histidine kinase
PKNEJCON_00229 8.4e-301 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
PKNEJCON_00230 3.9e-150 galR K Transcriptional regulator
PKNEJCON_00231 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PKNEJCON_00232 1.5e-283 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PKNEJCON_00233 5.6e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PKNEJCON_00234 1.9e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PKNEJCON_00235 0.0 lacS G transporter
PKNEJCON_00236 0.0 lacL 3.2.1.23 G -beta-galactosidase
PKNEJCON_00237 7.1e-209 S Tetratricopeptide repeat
PKNEJCON_00238 9.2e-158 yvgN C reductase
PKNEJCON_00239 6.7e-114 yoaK S Protein of unknown function (DUF1275)
PKNEJCON_00240 7.8e-109 drgA C nitroreductase
PKNEJCON_00241 5.5e-226 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKNEJCON_00242 2.6e-155 E Alpha/beta hydrolase of unknown function (DUF915)
PKNEJCON_00243 2.5e-77 ywnA K Transcriptional regulator
PKNEJCON_00244 4.5e-152 1.13.11.2 S glyoxalase
PKNEJCON_00245 2.4e-107 XK27_02070 S nitroreductase
PKNEJCON_00246 1.7e-29
PKNEJCON_00247 3.2e-27 XK27_07105 K transcriptional
PKNEJCON_00248 3.5e-142 K sequence-specific DNA binding
PKNEJCON_00249 1.7e-148 V ABC transporter, ATP-binding protein
PKNEJCON_00250 8e-94 S ABC-2 family transporter protein
PKNEJCON_00251 2.1e-147 K sequence-specific DNA binding
PKNEJCON_00252 1.3e-85
PKNEJCON_00253 3e-78 yfiQ K Acetyltransferase (GNAT) domain
PKNEJCON_00254 9.6e-141 S ABC-2 family transporter protein
PKNEJCON_00255 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PKNEJCON_00256 1.1e-108 L Transposase IS116 IS110 IS902
PKNEJCON_00257 9.2e-59 L MULE transposase domain
PKNEJCON_00258 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
PKNEJCON_00259 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
PKNEJCON_00260 7.8e-51 srlA G PTS system glucitol sorbitol-specific
PKNEJCON_00261 3.3e-32 L COG1943 Transposase and inactivated derivatives
PKNEJCON_00262 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PKNEJCON_00263 2.4e-234 dltB M Membrane protein involved in D-alanine export
PKNEJCON_00264 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PKNEJCON_00265 7e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PKNEJCON_00266 4.9e-92 G Citrate lyase beta subunit
PKNEJCON_00267 2.8e-27 3.1.3.12 S hydrolases of the HAD superfamily
PKNEJCON_00268 1.2e-291 ccs S the current gene model (or a revised gene model) may contain a frame shift
PKNEJCON_00269 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PKNEJCON_00270 1.7e-13
PKNEJCON_00271 1.6e-88 XK27_10930 K acetyltransferase
PKNEJCON_00272 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PKNEJCON_00273 7.2e-124 yaaA S Belongs to the UPF0246 family
PKNEJCON_00274 1.9e-167 XK27_01785 S cog cog1284
PKNEJCON_00275 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PKNEJCON_00277 7.3e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
PKNEJCON_00278 9e-31 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PKNEJCON_00279 4.6e-118 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PKNEJCON_00280 4.3e-53 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PKNEJCON_00281 4.7e-218 metE 2.1.1.14 E Methionine synthase
PKNEJCON_00282 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PKNEJCON_00283 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PKNEJCON_00284 7.5e-219 KLT Protein tyrosine kinase
PKNEJCON_00285 3.4e-94 tnp* L An automated process has identified a potential problem with this gene model
PKNEJCON_00286 4.9e-131 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
PKNEJCON_00287 3.8e-60 fruR K transcriptional
PKNEJCON_00288 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PKNEJCON_00289 5.8e-162 T Diguanylate cyclase
PKNEJCON_00291 2.2e-148 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PKNEJCON_00292 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
PKNEJCON_00293 0.0
PKNEJCON_00294 7.4e-07
PKNEJCON_00297 1.1e-115 nudL L hydrolase
PKNEJCON_00298 6.3e-54 K transcriptional regulator, PadR family
PKNEJCON_00299 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
PKNEJCON_00300 4.4e-107 S Putative adhesin
PKNEJCON_00301 2.8e-159 XK27_06930 V domain protein
PKNEJCON_00302 3.8e-96 XK27_06935 K transcriptional regulator
PKNEJCON_00303 4.1e-54 ypaA M Membrane
PKNEJCON_00304 1.4e-10
PKNEJCON_00305 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PKNEJCON_00306 1.8e-47 veg S Biofilm formation stimulator VEG
PKNEJCON_00307 3.8e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PKNEJCON_00308 2.2e-73 rplI J binds to the 23S rRNA
PKNEJCON_00309 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PKNEJCON_00310 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PKNEJCON_00311 2.5e-69 F NUDIX domain
PKNEJCON_00312 4.2e-99 yvbG U UPF0056 membrane protein
PKNEJCON_00313 1.9e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PKNEJCON_00314 7.8e-305 S Bacterial membrane protein, YfhO
PKNEJCON_00315 6.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
PKNEJCON_00316 6.6e-70 lytE M LysM domain protein
PKNEJCON_00317 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKNEJCON_00318 8.4e-151 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKNEJCON_00319 2.7e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PKNEJCON_00320 3.4e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PKNEJCON_00321 9.8e-131 S sequence-specific DNA binding
PKNEJCON_00322 1e-232 ymfH S Peptidase M16
PKNEJCON_00323 6.4e-232 ymfF S Peptidase M16
PKNEJCON_00324 8.3e-58 yaaA S S4 domain protein YaaA
PKNEJCON_00325 8.5e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PKNEJCON_00326 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PKNEJCON_00327 3.5e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PKNEJCON_00328 7.1e-153 yvjA S membrane
PKNEJCON_00329 1.1e-305 ybiT S abc transporter atp-binding protein
PKNEJCON_00330 0.0 XK27_10405 S Bacterial membrane protein YfhO
PKNEJCON_00334 2.4e-119 yoaK S Protein of unknown function (DUF1275)
PKNEJCON_00335 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PKNEJCON_00336 2.7e-206 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
PKNEJCON_00337 2.9e-134 parB K Belongs to the ParB family
PKNEJCON_00338 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PKNEJCON_00339 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PKNEJCON_00340 1.1e-29 yyzM S Protein conserved in bacteria
PKNEJCON_00341 4.3e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PKNEJCON_00342 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PKNEJCON_00343 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PKNEJCON_00344 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PKNEJCON_00345 3e-60 divIC D Septum formation initiator
PKNEJCON_00347 2.1e-233 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
PKNEJCON_00348 6.7e-237 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PKNEJCON_00349 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PKNEJCON_00350 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PKNEJCON_00351 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PKNEJCON_00352 1.1e-92 yybC
PKNEJCON_00353 3.2e-83 XK27_03610 K Gnat family
PKNEJCON_00354 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PKNEJCON_00355 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PKNEJCON_00356 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PKNEJCON_00357 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PKNEJCON_00358 2.5e-17 M LysM domain
PKNEJCON_00359 1.5e-86 ebsA S Family of unknown function (DUF5322)
PKNEJCON_00360 6.3e-232 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PKNEJCON_00361 3.5e-90 U ABC-2 type transporter
PKNEJCON_00362 7.8e-275 V ABC transporter transmembrane region
PKNEJCON_00365 4.5e-228 2.7.13.3 T GHKL domain
PKNEJCON_00366 1e-78 agrA KT Response regulator of the LytR AlgR family
PKNEJCON_00367 9e-75 XK27_03180 T universal stress protein
PKNEJCON_00369 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PKNEJCON_00370 2.5e-10 MU outer membrane autotransporter barrel domain protein
PKNEJCON_00371 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
PKNEJCON_00372 5.6e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
PKNEJCON_00373 0.0 yjcE P NhaP-type Na H and K H antiporters
PKNEJCON_00375 5.9e-97 ytqB J (SAM)-dependent
PKNEJCON_00376 3.5e-182 yhcC S radical SAM protein
PKNEJCON_00377 3.3e-184 ylbL T Belongs to the peptidase S16 family
PKNEJCON_00378 9.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PKNEJCON_00379 4.3e-92 rsmD 2.1.1.171 L Methyltransferase
PKNEJCON_00380 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PKNEJCON_00381 5e-10 S Protein of unknown function (DUF4059)
PKNEJCON_00382 1.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
PKNEJCON_00383 1.4e-162 yxeN P ABC transporter (Permease
PKNEJCON_00384 2.5e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PKNEJCON_00385 7.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PKNEJCON_00386 4.7e-35
PKNEJCON_00387 1.1e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PKNEJCON_00388 0.0 pflB 2.3.1.54 C formate acetyltransferase'
PKNEJCON_00389 1.7e-142 cah 4.2.1.1 P carbonic anhydrase
PKNEJCON_00390 6.2e-76 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PKNEJCON_00392 1.8e-170 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
PKNEJCON_00393 7e-141 cppA E CppA N-terminal
PKNEJCON_00394 7e-108 V CAAX protease self-immunity
PKNEJCON_00395 2.7e-193 L PFAM Integrase, catalytic core
PKNEJCON_00396 1.2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
PKNEJCON_00397 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PKNEJCON_00398 5.4e-44 spiA K sequence-specific DNA binding
PKNEJCON_00399 4.9e-136 blpT
PKNEJCON_00402 1e-216 ftsW D Belongs to the SEDS family
PKNEJCON_00403 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PKNEJCON_00404 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PKNEJCON_00405 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PKNEJCON_00406 1.5e-144 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PKNEJCON_00407 5.3e-44
PKNEJCON_00408 1.1e-56 S ParE toxin of type II toxin-antitoxin system, parDE
PKNEJCON_00409 1.1e-139 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PKNEJCON_00410 1.9e-77 P Mediates zinc uptake. May also transport other divalent cations
PKNEJCON_00411 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
PKNEJCON_00412 1.6e-61 smtB K Transcriptional regulator
PKNEJCON_00413 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PKNEJCON_00415 3.9e-116 Z012_10770 M Domain of unknown function (DUF1919)
PKNEJCON_00416 1.6e-188 sacB GT2,GT4 M Stealth protein CR3, conserved region 3
PKNEJCON_00417 1.3e-210 wcoF M Glycosyltransferase, group 1 family protein
PKNEJCON_00418 2.5e-222 rgpAc GT4 M group 1 family protein
PKNEJCON_00419 2.1e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PKNEJCON_00421 1.1e-219 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PKNEJCON_00422 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PKNEJCON_00423 0.0 ftsI 3.4.16.4 M penicillin-binding protein
PKNEJCON_00424 2.4e-45 ftsL D cell division protein FtsL
PKNEJCON_00425 2.6e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PKNEJCON_00426 5.4e-99
PKNEJCON_00429 4.5e-38 yhaI J Protein of unknown function (DUF805)
PKNEJCON_00430 1.4e-60 yhaI J Protein of unknown function (DUF805)
PKNEJCON_00431 5.4e-34 yhaI J Protein of unknown function (DUF805)
PKNEJCON_00432 3e-58 yhaI J Membrane
PKNEJCON_00433 1.6e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PKNEJCON_00434 1.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PKNEJCON_00435 4e-279 XK27_00765
PKNEJCON_00436 1.5e-132 ecsA_2 V abc transporter atp-binding protein
PKNEJCON_00437 1.4e-125 S Protein of unknown function (DUF554)
PKNEJCON_00438 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PKNEJCON_00439 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
PKNEJCON_00440 4e-243 2.7.13.3 T protein histidine kinase activity
PKNEJCON_00441 2.3e-232 dcuS 2.7.13.3 T protein histidine kinase activity
PKNEJCON_00442 1.5e-13
PKNEJCON_00445 1.7e-145 V Psort location CytoplasmicMembrane, score
PKNEJCON_00447 2.5e-297 O MreB/Mbl protein
PKNEJCON_00448 4.3e-49 mccF V LD-carboxypeptidase
PKNEJCON_00449 1.5e-220 M Psort location CytoplasmicMembrane, score
PKNEJCON_00450 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
PKNEJCON_00451 1e-22 S Psort location CytoplasmicMembrane, score
PKNEJCON_00452 7.1e-131 yaaT S stage 0 sporulation protein
PKNEJCON_00453 1.3e-159 holB 2.7.7.7 L dna polymerase iii
PKNEJCON_00454 1.5e-107 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PKNEJCON_00456 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PKNEJCON_00457 3.6e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PKNEJCON_00458 7.1e-12 ycdA S Domain of unknown function (DUF4352)
PKNEJCON_00459 2.2e-101 ybhL S Belongs to the BI1 family
PKNEJCON_00460 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
PKNEJCON_00461 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PKNEJCON_00462 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PKNEJCON_00463 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PKNEJCON_00464 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PKNEJCON_00465 5.1e-300 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PKNEJCON_00466 2.2e-87 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
PKNEJCON_00467 1.2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PKNEJCON_00468 8.2e-22
PKNEJCON_00469 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
PKNEJCON_00470 8.9e-276 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
PKNEJCON_00471 1.6e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PKNEJCON_00472 9.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PKNEJCON_00473 6.8e-95 ypsA S Belongs to the UPF0398 family
PKNEJCON_00474 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PKNEJCON_00475 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PKNEJCON_00476 5.8e-255 pepC 3.4.22.40 E aminopeptidase
PKNEJCON_00477 5.5e-53 yhaI L Membrane
PKNEJCON_00478 9e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PKNEJCON_00479 7.4e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PKNEJCON_00480 4.7e-217 macB_2 V FtsX-like permease family
PKNEJCON_00481 1.1e-119 yhcA V abc transporter atp-binding protein
PKNEJCON_00482 2.5e-124 mta K Transcriptional
PKNEJCON_00483 2.2e-30 S Protein of unknown function (DUF3021)
PKNEJCON_00484 9e-75 K COG3279 Response regulator of the LytR AlgR family
PKNEJCON_00485 1.2e-133 cylB V ABC-2 type transporter
PKNEJCON_00486 3.9e-151 cylA V abc transporter atp-binding protein
PKNEJCON_00487 9.6e-222 pepV 3.5.1.18 E Dipeptidase
PKNEJCON_00488 1.2e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
PKNEJCON_00490 1.8e-15 S Domain of unknown function (DUF3173)
PKNEJCON_00491 2.8e-182 L Belongs to the 'phage' integrase family
PKNEJCON_00492 4.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
PKNEJCON_00493 2.1e-45
PKNEJCON_00494 6.4e-50
PKNEJCON_00495 4.9e-148 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PKNEJCON_00496 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
PKNEJCON_00497 5e-85 yjlA EG membrane
PKNEJCON_00498 1.5e-34 copA 3.6.3.54 P P-type ATPase
PKNEJCON_00499 3.1e-12 spxB 1.2.3.3, 1.2.5.1 C Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg
PKNEJCON_00500 6.1e-146 G protein with an alpha beta hydrolase fold
PKNEJCON_00501 2.7e-126 ybhF_2 V abc transporter atp-binding protein
PKNEJCON_00502 1.8e-177 ybhR V ABC transporter
PKNEJCON_00503 5.7e-104 K Bacterial regulatory proteins, tetR family
PKNEJCON_00506 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PKNEJCON_00507 3.9e-171 vraS 2.7.13.3 T Histidine kinase
PKNEJCON_00508 6.6e-117 yvqF S Membrane
PKNEJCON_00509 3.4e-103 kcsA P Ion transport protein
PKNEJCON_00510 1.2e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
PKNEJCON_00511 1.3e-134 stp 3.1.3.16 T phosphatase
PKNEJCON_00512 2.4e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PKNEJCON_00513 4e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PKNEJCON_00514 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PKNEJCON_00515 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
PKNEJCON_00516 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PKNEJCON_00517 1.1e-192 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PKNEJCON_00518 7.9e-146 XK27_02985 S overlaps another CDS with the same product name
PKNEJCON_00519 1.4e-144 supH S overlaps another CDS with the same product name
PKNEJCON_00520 2.5e-62 yvoA_1 K Transcriptional
PKNEJCON_00521 5.4e-119 skfE V abc transporter atp-binding protein
PKNEJCON_00522 6.4e-129 V Psort location CytoplasmicMembrane, score
PKNEJCON_00523 1.2e-171 oppF P Belongs to the ABC transporter superfamily
PKNEJCON_00524 4.2e-203 oppD P Belongs to the ABC transporter superfamily
PKNEJCON_00525 1.4e-167 amiD P ABC transporter (Permease
PKNEJCON_00526 2.8e-274 amiC P ABC transporter (Permease
PKNEJCON_00527 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
PKNEJCON_00528 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PKNEJCON_00529 1.8e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PKNEJCON_00530 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PKNEJCON_00531 3.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PKNEJCON_00532 4.6e-120 yjbM 2.7.6.5 S Gtp pyrophosphokinase
PKNEJCON_00533 2.4e-101 yjbK S Adenylate cyclase
PKNEJCON_00534 1.9e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PKNEJCON_00535 2.9e-47
PKNEJCON_00536 2.7e-100 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
PKNEJCON_00537 9e-104 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PKNEJCON_00538 3e-14 coiA 3.6.4.12 S Competence protein
PKNEJCON_00539 2.2e-15 T peptidase
PKNEJCON_00540 3.4e-153 L PFAM Integrase catalytic region
PKNEJCON_00541 2.7e-183 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
PKNEJCON_00542 4.8e-199 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PKNEJCON_00543 3.4e-71 czcD P cation diffusion facilitator family transporter
PKNEJCON_00544 7.5e-145
PKNEJCON_00545 7.1e-277 5.1.3.2 GM Psort location CytoplasmicMembrane, score
PKNEJCON_00546 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
PKNEJCON_00547 7.9e-121 yhfC S Putative membrane peptidase family (DUF2324)
PKNEJCON_00548 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PKNEJCON_00549 4.3e-141 S Phenazine biosynthesis protein
PKNEJCON_00550 7.7e-89 tetR K transcriptional regulator
PKNEJCON_00551 4.3e-124 V abc transporter atp-binding protein
PKNEJCON_00552 1.2e-214 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PKNEJCON_00553 5e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PKNEJCON_00554 3.8e-153 gst O Glutathione S-transferase
PKNEJCON_00555 6.5e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
PKNEJCON_00556 3.5e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PKNEJCON_00557 0.0 fruA 2.7.1.202 G phosphotransferase system
PKNEJCON_00558 1.7e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PKNEJCON_00559 2.7e-124 fruR K transcriptional
PKNEJCON_00560 1.9e-107 S unusual protein kinase
PKNEJCON_00561 2e-101 estA E Lysophospholipase L1 and related esterases
PKNEJCON_00562 5.3e-153 rssA S Phospholipase, patatin family
PKNEJCON_00563 6.5e-182 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PKNEJCON_00564 1.1e-31 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PKNEJCON_00565 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
PKNEJCON_00566 4.8e-122 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PKNEJCON_00567 8.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
PKNEJCON_00568 1.5e-132 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PKNEJCON_00569 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
PKNEJCON_00570 1.2e-161 ylbM S Belongs to the UPF0348 family
PKNEJCON_00571 3.4e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PKNEJCON_00572 1.6e-44 yoeB S Addiction module toxin, Txe YoeB family
PKNEJCON_00574 1.3e-146 sdaAA 4.3.1.17 E L-serine dehydratase
PKNEJCON_00575 2.5e-121 sdaAB 4.3.1.17 E L-serine dehydratase
PKNEJCON_00576 1.6e-103
PKNEJCON_00578 4.3e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PKNEJCON_00579 3.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PKNEJCON_00580 1.4e-65 alkD L Dna alkylation repair
PKNEJCON_00581 1.4e-48
PKNEJCON_00582 1.3e-33 L Transposase
PKNEJCON_00583 1.5e-23 L An automated process has identified a potential problem with this gene model
PKNEJCON_00584 1.6e-27 bipA S protein secretion
PKNEJCON_00585 1.3e-23 L the current gene model (or a revised gene model) may contain a frame shift
PKNEJCON_00586 7.4e-95 L Transposase
PKNEJCON_00587 1.5e-30 L PFAM transposase IS116 IS110 IS902 family
PKNEJCON_00588 0.0 zmpB M signal peptide protein, YSIRK family
PKNEJCON_00589 0.0 GM domain, Protein
PKNEJCON_00590 4.2e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PKNEJCON_00591 0.0 sbcC L ATPase involved in DNA repair
PKNEJCON_00592 0.0 M family 8
PKNEJCON_00593 2.8e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
PKNEJCON_00594 9.4e-289 asp1 S Accessory Sec system protein Asp1
PKNEJCON_00595 4.1e-289 asp2 3.4.11.5 S Accessory Sec system protein Asp2
PKNEJCON_00596 1e-78 asp3 S Accessory Sec system protein Asp3
PKNEJCON_00597 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PKNEJCON_00598 1.1e-129 dprA LU DNA protecting protein DprA
PKNEJCON_00599 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PKNEJCON_00600 2.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PKNEJCON_00601 3.4e-14 rpmH J Ribosomal protein L34
PKNEJCON_00602 1.2e-97 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
PKNEJCON_00603 1.7e-97 K Transcriptional regulator
PKNEJCON_00604 5.8e-170 jag S RNA-binding protein
PKNEJCON_00605 3.2e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PKNEJCON_00606 1.3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PKNEJCON_00607 1.6e-263 argH 4.3.2.1 E Argininosuccinate lyase
PKNEJCON_00608 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PKNEJCON_00609 7.2e-130 fasA KT Response regulator of the LytR AlgR family
PKNEJCON_00610 8e-225 fasC 2.7.13.3 T protein histidine kinase activity
PKNEJCON_00611 4.2e-210 hpk9 2.7.13.3 T protein histidine kinase activity
PKNEJCON_00612 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
PKNEJCON_00613 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
PKNEJCON_00614 5.7e-272 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PKNEJCON_00615 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PKNEJCON_00616 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PKNEJCON_00617 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PKNEJCON_00618 1.2e-50 S Protein of unknown function (DUF3397)
PKNEJCON_00619 7.3e-86 cah 4.2.1.1 P Reversible hydration of carbon dioxide
PKNEJCON_00620 2.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
PKNEJCON_00621 4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PKNEJCON_00622 4.6e-75 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PKNEJCON_00623 2.7e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PKNEJCON_00624 8.2e-108 XK27_09620 S FMN reductase (NADPH) activity
PKNEJCON_00625 1.8e-229 XK27_09615 C reductase
PKNEJCON_00626 2e-138 fnt P Formate nitrite transporter
PKNEJCON_00627 3.3e-95 XK27_08585 S Psort location CytoplasmicMembrane, score
PKNEJCON_00628 2.2e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PKNEJCON_00629 1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PKNEJCON_00630 4.4e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
PKNEJCON_00631 2.2e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PKNEJCON_00632 1.5e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PKNEJCON_00633 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PKNEJCON_00634 8.6e-139 S HAD hydrolase, family IA, variant
PKNEJCON_00635 8.3e-159 rrmA 2.1.1.187 Q methyltransferase
PKNEJCON_00639 5.6e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PKNEJCON_00640 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PKNEJCON_00641 8.3e-37 yeeD O sulfur carrier activity
PKNEJCON_00642 2.6e-186 yeeE S Sulphur transport
PKNEJCON_00643 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PKNEJCON_00645 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PKNEJCON_00646 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
PKNEJCON_00647 1.4e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PKNEJCON_00648 1.8e-128 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PKNEJCON_00649 1.4e-100 S CAAX amino terminal protease family protein
PKNEJCON_00651 2.2e-106 V CAAX protease self-immunity
PKNEJCON_00652 8.8e-27 lanR K sequence-specific DNA binding
PKNEJCON_00653 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PKNEJCON_00654 3.8e-176 ytxK 2.1.1.72 L DNA methylase
PKNEJCON_00655 2e-12 comGF U Putative Competence protein ComGF
PKNEJCON_00656 1.3e-70 comGF U Competence protein ComGF
PKNEJCON_00657 5.3e-15 NU Type II secretory pathway pseudopilin
PKNEJCON_00658 1.4e-69 cglD NU Competence protein
PKNEJCON_00659 2.2e-43 comGC U Required for transformation and DNA binding
PKNEJCON_00660 7.4e-144 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PKNEJCON_00661 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PKNEJCON_00662 1e-68 S cog cog4699
PKNEJCON_00663 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKNEJCON_00664 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKNEJCON_00665 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PKNEJCON_00666 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PKNEJCON_00667 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PKNEJCON_00668 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
PKNEJCON_00669 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
PKNEJCON_00670 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PKNEJCON_00671 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
PKNEJCON_00672 1.4e-57 asp S cog cog1302
PKNEJCON_00673 2.1e-225 norN V Mate efflux family protein
PKNEJCON_00674 1e-276 thrC 4.2.3.1 E Threonine synthase
PKNEJCON_00677 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PKNEJCON_00678 0.0 pepO 3.4.24.71 O Peptidase family M13
PKNEJCON_00679 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PKNEJCON_00680 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PKNEJCON_00681 6e-126 treR K trehalose operon
PKNEJCON_00682 3.7e-94 ywlG S Belongs to the UPF0340 family
PKNEJCON_00684 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
PKNEJCON_00686 1.6e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
PKNEJCON_00687 4.4e-62 rplQ J ribosomal protein l17
PKNEJCON_00688 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PKNEJCON_00689 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PKNEJCON_00690 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PKNEJCON_00691 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PKNEJCON_00692 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PKNEJCON_00693 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PKNEJCON_00694 3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PKNEJCON_00695 5.7e-58 rplO J binds to the 23S rRNA
PKNEJCON_00696 1.9e-23 rpmD J ribosomal protein l30
PKNEJCON_00697 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PKNEJCON_00698 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PKNEJCON_00699 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PKNEJCON_00700 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PKNEJCON_00701 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PKNEJCON_00702 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PKNEJCON_00703 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PKNEJCON_00704 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PKNEJCON_00705 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PKNEJCON_00706 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
PKNEJCON_00707 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PKNEJCON_00708 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PKNEJCON_00709 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PKNEJCON_00710 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PKNEJCON_00711 7.5e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PKNEJCON_00712 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PKNEJCON_00713 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
PKNEJCON_00714 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PKNEJCON_00715 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
PKNEJCON_00716 1.1e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PKNEJCON_00717 0.0 XK27_09800 I Acyltransferase
PKNEJCON_00718 9.7e-36 XK27_09805 S MORN repeat protein
PKNEJCON_00719 3.4e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PKNEJCON_00720 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PKNEJCON_00721 5.9e-91 adk 2.7.4.3 F topology modulation protein
PKNEJCON_00723 1.1e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
PKNEJCON_00724 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PKNEJCON_00725 6.3e-44 yrzL S Belongs to the UPF0297 family
PKNEJCON_00726 4e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PKNEJCON_00727 3.2e-44 yrzB S Belongs to the UPF0473 family
PKNEJCON_00728 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PKNEJCON_00729 5.4e-115 pgi 5.3.1.9 G Belongs to the GPI family
PKNEJCON_00730 2.6e-158 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
PKNEJCON_00731 5.1e-117
PKNEJCON_00732 1.9e-141 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PKNEJCON_00733 2.2e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PKNEJCON_00734 1.7e-160 GK ROK family
PKNEJCON_00735 5.7e-283 pstB11 P ABC transporter transmembrane region
PKNEJCON_00736 2e-189 agcS E (Alanine) symporter
PKNEJCON_00737 3.3e-245 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PKNEJCON_00738 1.3e-170 bglC K Transcriptional regulator
PKNEJCON_00739 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
PKNEJCON_00740 2.4e-81 yecS P ABC transporter (Permease
PKNEJCON_00741 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
PKNEJCON_00742 2.3e-241 nylA 3.5.1.4 J Belongs to the amidase family
PKNEJCON_00743 9.8e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PKNEJCON_00744 2.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PKNEJCON_00745 2.7e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PKNEJCON_00746 7.7e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PKNEJCON_00747 6.8e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
PKNEJCON_00748 2e-133 S TraX protein
PKNEJCON_00749 6.2e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PKNEJCON_00750 3e-271 S Psort location CytoplasmicMembrane, score
PKNEJCON_00751 4.4e-88 V ABC transporter, ATP-binding protein
PKNEJCON_00752 1.9e-47
PKNEJCON_00753 1e-224 dinF V Mate efflux family protein
PKNEJCON_00754 1.3e-179 yclQ P ABC-type enterochelin transport system, periplasmic component
PKNEJCON_00755 3.4e-149 S von Willebrand factor (vWF) type A domain
PKNEJCON_00756 0.0 V Type III restriction enzyme, res subunit
PKNEJCON_00757 4.3e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
PKNEJCON_00758 1.1e-23 udp 2.4.2.3 F phosphorylase
PKNEJCON_00759 6.4e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PKNEJCON_00760 1.8e-87 pat 2.3.1.183 M acetyltransferase
PKNEJCON_00761 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PKNEJCON_00762 8.4e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PKNEJCON_00763 1.2e-192 yhjX P Major Facilitator
PKNEJCON_00764 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PKNEJCON_00765 1.2e-84 V VanZ like family
PKNEJCON_00766 2.1e-184 D nuclear chromosome segregation
PKNEJCON_00767 2.2e-123 glnQ E abc transporter atp-binding protein
PKNEJCON_00768 7.9e-272 glnP P ABC transporter
PKNEJCON_00769 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PKNEJCON_00770 4.8e-18 S Protein of unknown function (DUF3021)
PKNEJCON_00771 2e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PKNEJCON_00772 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
PKNEJCON_00773 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PKNEJCON_00774 9.1e-234 sufD O assembly protein SufD
PKNEJCON_00775 2.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PKNEJCON_00776 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
PKNEJCON_00777 2.9e-273 sufB O assembly protein SufB
PKNEJCON_00778 1.8e-25
PKNEJCON_00779 1.8e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PKNEJCON_00780 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PKNEJCON_00781 1e-70 adcR K transcriptional
PKNEJCON_00782 8.3e-136 adcC P ABC transporter, ATP-binding protein
PKNEJCON_00783 1.9e-128 adcB P ABC transporter (Permease
PKNEJCON_00784 5.5e-159 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PKNEJCON_00785 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PKNEJCON_00786 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
PKNEJCON_00789 2.7e-228 2.7.13.3 T GHKL domain
PKNEJCON_00790 9.9e-132 agrA KT phosphorelay signal transduction system
PKNEJCON_00791 2.4e-07
PKNEJCON_00792 3.6e-114 agrA KT response regulator
PKNEJCON_00793 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PKNEJCON_00795 5.3e-10
PKNEJCON_00796 0.0 cbpD 3.5.1.28 NU GBS Bsp-like repeat
PKNEJCON_00797 1.5e-164 K sequence-specific DNA binding
PKNEJCON_00798 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PKNEJCON_00799 3e-84 yxjI S LURP-one-related
PKNEJCON_00800 5.1e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
PKNEJCON_00801 1.5e-118 yrrM 2.1.1.104 S O-Methyltransferase
PKNEJCON_00802 1.3e-205 oxlT P COG0477 Permeases of the major facilitator superfamily
PKNEJCON_00803 0.0 pepF E oligoendopeptidase F
PKNEJCON_00804 4.5e-177 coiA 3.6.4.12 S Competence protein
PKNEJCON_00805 4e-273 S Glucan-binding protein C
PKNEJCON_00806 1.3e-107 S CAAX amino terminal protease family protein
PKNEJCON_00807 4.7e-168 K transcriptional regulator (lysR family)
PKNEJCON_00808 2e-160 S reductase
PKNEJCON_00809 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PKNEJCON_00815 3.4e-189 phoH T phosphate starvation-inducible protein PhoH
PKNEJCON_00816 2.2e-126 sip M LysM domain protein
PKNEJCON_00817 3.7e-34 yozE S Belongs to the UPF0346 family
PKNEJCON_00818 8.5e-159 cvfB S Protein conserved in bacteria
PKNEJCON_00819 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PKNEJCON_00820 8.4e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PKNEJCON_00821 6.8e-210 sptS 2.7.13.3 T Histidine kinase
PKNEJCON_00822 2.9e-117 T response regulator
PKNEJCON_00823 3.3e-112 2.7.6.5 S Region found in RelA / SpoT proteins
PKNEJCON_00824 1.5e-112 K Acetyltransferase (GNAT) family
PKNEJCON_00825 0.0 lmrA2 V abc transporter atp-binding protein
PKNEJCON_00826 2.5e-311 lmrA1 V abc transporter atp-binding protein
PKNEJCON_00827 8.8e-75 K DNA-binding transcription factor activity
PKNEJCON_00828 2.3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PKNEJCON_00829 6.2e-283 S Psort location CytoplasmicMembrane, score
PKNEJCON_00830 1.5e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PKNEJCON_00832 3e-209 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
PKNEJCON_00833 3.1e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
PKNEJCON_00834 1.3e-26 U response to pH
PKNEJCON_00835 0.0 yfmR S abc transporter atp-binding protein
PKNEJCON_00836 6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PKNEJCON_00837 2.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PKNEJCON_00838 6.2e-146 XK27_08360 S EDD domain protein, DegV family
PKNEJCON_00839 5e-63 WQ51_03320 S cog cog4835
PKNEJCON_00840 2.5e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PKNEJCON_00841 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PKNEJCON_00842 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PKNEJCON_00843 2.5e-84 2.3.1.128 K acetyltransferase
PKNEJCON_00844 1.2e-252 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PKNEJCON_00845 1.8e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PKNEJCON_00846 2.8e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PKNEJCON_00847 4.4e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
PKNEJCON_00849 1.6e-230 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PKNEJCON_00850 7.9e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PKNEJCON_00852 1.9e-24 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
PKNEJCON_00853 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PKNEJCON_00854 2.8e-37
PKNEJCON_00855 1.9e-186 lplA 6.3.1.20 H Lipoate-protein ligase
PKNEJCON_00856 3.5e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
PKNEJCON_00857 0.0 pepN 3.4.11.2 E aminopeptidase
PKNEJCON_00858 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
PKNEJCON_00859 5.1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PKNEJCON_00860 1.2e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PKNEJCON_00861 9.1e-156 pstA P phosphate transport system permease
PKNEJCON_00862 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
PKNEJCON_00863 2.6e-155 pstS P phosphate
PKNEJCON_00864 1.3e-246 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PKNEJCON_00865 2.9e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PKNEJCON_00866 1e-44 yktA S Belongs to the UPF0223 family
PKNEJCON_00867 7.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PKNEJCON_00868 3.9e-170 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PKNEJCON_00869 9.6e-147 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PKNEJCON_00870 2.8e-241 XK27_04775 S hemerythrin HHE cation binding domain
PKNEJCON_00871 1e-34 M1-755 P Hemerythrin HHE cation binding domain protein
PKNEJCON_00872 4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
PKNEJCON_00873 3.6e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PKNEJCON_00874 6.9e-30 S haloacid dehalogenase-like hydrolase
PKNEJCON_00875 2.3e-99 S haloacid dehalogenase-like hydrolase
PKNEJCON_00876 1.5e-239 metY 2.5.1.49 E o-acetylhomoserine
PKNEJCON_00877 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PKNEJCON_00878 4.8e-255 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PKNEJCON_00879 3.8e-111 serB 3.1.3.3 E phosphoserine phosphatase
PKNEJCON_00880 8.5e-08 N PFAM Uncharacterised protein family UPF0150
PKNEJCON_00881 2.6e-150 EG Permeases of the drug metabolite transporter (DMT) superfamily
PKNEJCON_00883 7e-62 ycaO O OsmC-like protein
PKNEJCON_00884 1.1e-62 paaI Q protein possibly involved in aromatic compounds catabolism
PKNEJCON_00885 4.4e-10 O ADP-ribosylglycohydrolase
PKNEJCON_00886 4.9e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PKNEJCON_00888 1.5e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PKNEJCON_00889 1.7e-17 XK27_00735
PKNEJCON_00890 8.7e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
PKNEJCON_00891 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
PKNEJCON_00892 4e-162 S CAAX amino terminal protease family protein
PKNEJCON_00894 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PKNEJCON_00895 2.3e-78 mutT 3.6.1.55 F Nudix family
PKNEJCON_00896 3.8e-140 ET ABC transporter
PKNEJCON_00897 3.2e-136 ET Belongs to the bacterial solute-binding protein 3 family
PKNEJCON_00898 3.3e-211 arcT 2.6.1.1 E Aminotransferase
PKNEJCON_00899 4.4e-133 gltS ET Belongs to the bacterial solute-binding protein 3 family
PKNEJCON_00900 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PKNEJCON_00901 8.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PKNEJCON_00902 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PKNEJCON_00903 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PKNEJCON_00904 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
PKNEJCON_00905 1e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PKNEJCON_00906 7.4e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PKNEJCON_00907 1.3e-199 metB 2.5.1.48, 4.4.1.8 E cystathionine
PKNEJCON_00908 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
PKNEJCON_00909 7.8e-289 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
PKNEJCON_00910 9e-270 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PKNEJCON_00911 3.5e-190 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
PKNEJCON_00912 1.1e-98 yvdD 3.2.2.10 S Belongs to the LOG family
PKNEJCON_00913 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PKNEJCON_00914 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PKNEJCON_00915 1.4e-41 ylxQ J ribosomal protein
PKNEJCON_00916 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
PKNEJCON_00917 2.4e-196 nusA K Participates in both transcription termination and antitermination
PKNEJCON_00918 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
PKNEJCON_00919 1.2e-185 brpA K Transcriptional
PKNEJCON_00920 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
PKNEJCON_00921 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
PKNEJCON_00922 1.6e-247 pbuO S permease
PKNEJCON_00923 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
PKNEJCON_00924 1.3e-136 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
PKNEJCON_00925 8.1e-169 manL 2.7.1.191 G pts system
PKNEJCON_00926 4.7e-135 manY G pts system
PKNEJCON_00927 4.6e-163 manN G PTS system mannose fructose sorbose family IID component
PKNEJCON_00928 7.7e-67 manO S Protein conserved in bacteria
PKNEJCON_00929 8.9e-176 manL 2.7.1.191 G pts system
PKNEJCON_00930 4.2e-115 manM G pts system
PKNEJCON_00931 4e-167 manN G PTS system mannose fructose sorbose family IID component
PKNEJCON_00932 7.2e-62 manO S protein conserved in bacteria
PKNEJCON_00933 1.5e-228 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PKNEJCON_00934 8.5e-111
PKNEJCON_00935 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PKNEJCON_00936 1.3e-165 dnaI L Primosomal protein DnaI
PKNEJCON_00937 5.9e-211 dnaB L Replication initiation and membrane attachment
PKNEJCON_00938 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PKNEJCON_00939 4e-276 T PhoQ Sensor
PKNEJCON_00940 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PKNEJCON_00941 3.1e-90 yceD K metal-binding, possibly nucleic acid-binding protein
PKNEJCON_00942 2.5e-127 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
PKNEJCON_00943 1.1e-237 P COG0168 Trk-type K transport systems, membrane components
PKNEJCON_00944 8e-120 ktrA P COG0569 K transport systems, NAD-binding component
PKNEJCON_00945 2e-149 cbiQ P cobalt transport
PKNEJCON_00946 8.7e-309 ykoD P abc transporter atp-binding protein
PKNEJCON_00947 2e-92 S UPF0397 protein
PKNEJCON_00948 2.5e-155 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
PKNEJCON_00949 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PKNEJCON_00950 8e-99 metI P ABC transporter (Permease
PKNEJCON_00951 1.4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PKNEJCON_00952 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
PKNEJCON_00953 1.9e-164 metQ M Belongs to the NlpA lipoprotein family
PKNEJCON_00954 6.3e-138 ET ABC transporter substrate-binding protein
PKNEJCON_00955 6.3e-131 cbiO P ABC transporter
PKNEJCON_00956 6e-135 P cobalt transport protein
PKNEJCON_00957 1.1e-175 cbiM P PDGLE domain
PKNEJCON_00958 4e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PKNEJCON_00959 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PKNEJCON_00960 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PKNEJCON_00961 6.6e-78 ureE O enzyme active site formation
PKNEJCON_00962 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PKNEJCON_00963 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PKNEJCON_00964 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PKNEJCON_00965 6.8e-95 ureI S AmiS/UreI family transporter
PKNEJCON_00966 8.7e-254 S Domain of unknown function (DUF4173)
PKNEJCON_00967 1.3e-54 yhaI L Membrane
PKNEJCON_00968 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PKNEJCON_00969 1.2e-152 K sequence-specific DNA binding
PKNEJCON_00970 4.4e-107 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
PKNEJCON_00971 1.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PKNEJCON_00972 4.4e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PKNEJCON_00973 1e-246 trkA P Potassium transporter peripheral membrane component
PKNEJCON_00974 9.3e-259 trkH P Cation transport protein
PKNEJCON_00975 5.9e-25 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PKNEJCON_00976 3e-87 S Fusaric acid resistance protein-like
PKNEJCON_00977 2.5e-62 glnR K Transcriptional regulator
PKNEJCON_00978 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
PKNEJCON_00979 3.6e-114 pscB M CHAP domain protein
PKNEJCON_00980 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PKNEJCON_00981 1.5e-33 ykzG S Belongs to the UPF0356 family
PKNEJCON_00982 1.8e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
PKNEJCON_00983 9e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PKNEJCON_00984 4.3e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PKNEJCON_00985 3e-114 azlC E AzlC protein
PKNEJCON_00986 1.3e-46 azlD S branched-chain amino acid
PKNEJCON_00987 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PKNEJCON_00988 5.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PKNEJCON_00989 3.8e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PKNEJCON_00990 1.4e-26 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PKNEJCON_00991 6.9e-90 cvpA S toxin biosynthetic process
PKNEJCON_00992 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PKNEJCON_00993 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PKNEJCON_00995 4.2e-33
PKNEJCON_00997 1.5e-222 mutY L A G-specific adenine glycosylase
PKNEJCON_00998 1.3e-43 XK27_05745
PKNEJCON_01000 9.6e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
PKNEJCON_01001 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PKNEJCON_01002 7.1e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
PKNEJCON_01003 1.3e-26 P Hemerythrin HHE cation binding domain protein
PKNEJCON_01004 4.1e-158 5.2.1.8 G hydrolase
PKNEJCON_01005 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PKNEJCON_01006 5.2e-212 MA20_36090 S Protein of unknown function (DUF2974)
PKNEJCON_01007 2.1e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PKNEJCON_01008 5.5e-44 K Helix-turn-helix domain
PKNEJCON_01009 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PKNEJCON_01010 1.8e-75 S Protein of unknown function (DUF1524)
PKNEJCON_01011 9.8e-121 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PKNEJCON_01012 7e-28
PKNEJCON_01013 9.2e-126
PKNEJCON_01014 5.6e-305 hsdM 2.1.1.72 V type I restriction-modification system
PKNEJCON_01015 1.3e-136 S double-stranded DNA endodeoxyribonuclease activity
PKNEJCON_01016 0.0 2.4.1.21 GT5 M Right handed beta helix region
PKNEJCON_01017 9.9e-175 spd F DNA RNA non-specific endonuclease
PKNEJCON_01018 1e-91 lemA S LemA family
PKNEJCON_01019 4e-135 htpX O Belongs to the peptidase M48B family
PKNEJCON_01020 5e-119 sirR K iron dependent repressor
PKNEJCON_01021 2.8e-171 sitA P Belongs to the bacterial solute-binding protein 9 family
PKNEJCON_01022 1.6e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
PKNEJCON_01023 8.1e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
PKNEJCON_01024 7.6e-75 S Psort location CytoplasmicMembrane, score
PKNEJCON_01025 5.6e-65 S Domain of unknown function (DUF4430)
PKNEJCON_01026 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PKNEJCON_01027 4.1e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
PKNEJCON_01028 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
PKNEJCON_01029 1.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
PKNEJCON_01030 2.4e-105 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
PKNEJCON_01031 1.1e-89 dps P Belongs to the Dps family
PKNEJCON_01032 3.4e-79 perR P Belongs to the Fur family
PKNEJCON_01033 7.1e-27 yqgQ S protein conserved in bacteria
PKNEJCON_01034 1.7e-176 glk 2.7.1.2 G Glucokinase
PKNEJCON_01035 0.0 typA T GTP-binding protein TypA
PKNEJCON_01037 7.4e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PKNEJCON_01038 4.7e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PKNEJCON_01039 2.6e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PKNEJCON_01040 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PKNEJCON_01041 1.6e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PKNEJCON_01042 3.9e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PKNEJCON_01043 2.2e-86 sepF D cell septum assembly
PKNEJCON_01044 7.7e-31 yggT D integral membrane protein
PKNEJCON_01045 9.5e-144 ylmH S conserved protein, contains S4-like domain
PKNEJCON_01046 8.4e-138 divIVA D Cell division initiation protein
PKNEJCON_01047 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PKNEJCON_01048 5.5e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PKNEJCON_01049 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PKNEJCON_01050 2.2e-34 nrdH O Glutaredoxin
PKNEJCON_01051 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PKNEJCON_01052 2.1e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
PKNEJCON_01053 1.7e-221 icd 1.1.1.42 C Isocitrate dehydrogenase
PKNEJCON_01054 3e-38 ptsH G phosphocarrier protein Hpr
PKNEJCON_01055 4.9e-202 P FtsX-like permease family
PKNEJCON_01056 1.5e-42 S Sugar efflux transporter for intercellular exchange
PKNEJCON_01057 1.4e-62 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PKNEJCON_01058 0.0 S dextransucrase activity
PKNEJCON_01059 7.2e-216 yfnA E amino acid
PKNEJCON_01060 1.5e-50 XK27_01300 P Protein conserved in bacteria
PKNEJCON_01061 1.3e-101 S Carbohydrate-binding domain-containing protein Cthe_2159
PKNEJCON_01062 1.1e-16 csbD S CsbD-like
PKNEJCON_01063 1.5e-107 S Protein of unknown function (DUF421)
PKNEJCON_01064 3.1e-59 S Protein of unknown function (DUF3290)
PKNEJCON_01065 7.8e-182 manA 5.3.1.8 G mannose-6-phosphate isomerase
PKNEJCON_01066 6.8e-232 brnQ E Component of the transport system for branched-chain amino acids
PKNEJCON_01067 1.7e-179 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PKNEJCON_01069 4.6e-244 norM V Multidrug efflux pump
PKNEJCON_01070 3.7e-143 K sequence-specific DNA binding
PKNEJCON_01071 1.1e-273 V (ABC) transporter
PKNEJCON_01072 3.8e-224 pbuX F xanthine permease
PKNEJCON_01073 1.8e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PKNEJCON_01074 9.5e-177 EGP Major facilitator Superfamily
PKNEJCON_01075 1.4e-72 copY K negative regulation of transcription, DNA-templated
PKNEJCON_01076 0.0 copA 3.6.3.54 P P-type ATPase
PKNEJCON_01077 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
PKNEJCON_01078 1.5e-34 K Transcriptional regulator C-terminal region
PKNEJCON_01079 2.2e-83 V ABC transporter
PKNEJCON_01080 2.5e-56
PKNEJCON_01081 6.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PKNEJCON_01082 3.9e-114 papP P ABC transporter (Permease
PKNEJCON_01083 1.3e-106 P ABC transporter (Permease
PKNEJCON_01084 1.5e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
PKNEJCON_01085 3.3e-155 cjaA ET ABC transporter substrate-binding protein
PKNEJCON_01089 7.8e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PKNEJCON_01090 2.2e-114 ywaF S Integral membrane protein (intg_mem_TP0381)
PKNEJCON_01091 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PKNEJCON_01092 1.7e-99 thiT S Thiamine transporter
PKNEJCON_01093 3.3e-62 yjqA S Bacterial PH domain
PKNEJCON_01094 1.6e-152 corA P CorA-like protein
PKNEJCON_01095 1.6e-243 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PKNEJCON_01096 7.2e-160 S Hydrophobic domain protein
PKNEJCON_01097 1.1e-40 yazA L endonuclease containing a URI domain
PKNEJCON_01098 5.1e-139 yabB 2.1.1.223 L Methyltransferase
PKNEJCON_01099 2.3e-141 nodB3 G deacetylase
PKNEJCON_01100 1.1e-141 plsC 2.3.1.51 I Acyltransferase
PKNEJCON_01101 2.4e-95 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PKNEJCON_01102 0.0 comEC S Competence protein ComEC
PKNEJCON_01103 2.1e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PKNEJCON_01104 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
PKNEJCON_01105 3e-232 ytoI K transcriptional regulator containing CBS domains
PKNEJCON_01106 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
PKNEJCON_01107 4.8e-163 rbn E Belongs to the UPF0761 family
PKNEJCON_01108 1.7e-85 ccl S cog cog4708
PKNEJCON_01109 1.9e-271 L Domain of unknown function (DUF4368)
PKNEJCON_01111 8.8e-115 S Replication-relaxation
PKNEJCON_01112 0.0 yukA S Type IV secretion-system coupling protein DNA-binding domain
PKNEJCON_01113 8.9e-102 KT MT-A70
PKNEJCON_01115 4.2e-24
PKNEJCON_01116 1.3e-127
PKNEJCON_01117 5.2e-193 sthIM 2.1.1.72 L DNA methylase
PKNEJCON_01118 0.0 res_1 3.1.21.5 S DEAD-like helicases superfamily
PKNEJCON_01119 2.9e-130 S AAA ATPase domain
PKNEJCON_01120 3.2e-167 S cog cog0433
PKNEJCON_01121 5e-101 S SIR2-like domain
PKNEJCON_01122 6.9e-63 L Helix-turn-helix domain
PKNEJCON_01123 3.2e-94 L HTH-like domain
PKNEJCON_01124 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PKNEJCON_01125 3.8e-182 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PKNEJCON_01127 4e-168 yfjR K regulation of single-species biofilm formation
PKNEJCON_01130 5.6e-85 yfjR K regulation of single-species biofilm formation
PKNEJCON_01131 1.2e-129 S Protein of unknown function DUF262
PKNEJCON_01132 1.2e-203 S Protein of unknown function DUF262
PKNEJCON_01133 2.8e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PKNEJCON_01134 1.5e-189 desK 2.7.13.3 T Histidine kinase
PKNEJCON_01135 2e-132 yvfS V ABC-2 type transporter
PKNEJCON_01136 9.7e-158 XK27_09825 V 'abc transporter, ATP-binding protein
PKNEJCON_01140 7.3e-205 anK3 G response to abiotic stimulus
PKNEJCON_01141 0.0 hscC O Belongs to the heat shock protein 70 family
PKNEJCON_01142 5.7e-147 yocS S Transporter
PKNEJCON_01143 1.4e-80 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
PKNEJCON_01144 3.1e-117 yvfS V Transporter
PKNEJCON_01145 3.1e-156 XK27_09825 V abc transporter atp-binding protein
PKNEJCON_01146 3.3e-16 liaI KT membrane
PKNEJCON_01147 6.8e-31 liaI KT membrane
PKNEJCON_01148 6.1e-93 XK27_05000 S metal cluster binding
PKNEJCON_01149 0.0 V ABC transporter (permease)
PKNEJCON_01150 1.4e-133 macB2 V ABC transporter, ATP-binding protein
PKNEJCON_01151 1.3e-150 T Histidine kinase
PKNEJCON_01152 2e-138 potB P ABC-type spermidine putrescine transport system, permease component I
PKNEJCON_01153 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PKNEJCON_01154 2.1e-168 murB 1.3.1.98 M cell wall formation
PKNEJCON_01155 2.2e-79 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PKNEJCON_01156 1.3e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PKNEJCON_01157 4.6e-290 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
PKNEJCON_01158 5.9e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PKNEJCON_01159 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
PKNEJCON_01160 0.0 ydaO E amino acid
PKNEJCON_01161 1.2e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PKNEJCON_01162 1.5e-36 ylqC L Belongs to the UPF0109 family
PKNEJCON_01163 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PKNEJCON_01165 4.8e-201 2.7.13.3 T protein histidine kinase activity
PKNEJCON_01166 2.6e-124 agrA KT phosphorelay signal transduction system
PKNEJCON_01167 2.7e-164 O protein import
PKNEJCON_01168 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
PKNEJCON_01169 2.2e-17 yjdB S Domain of unknown function (DUF4767)
PKNEJCON_01170 1.4e-90 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PKNEJCON_01172 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
PKNEJCON_01173 8.2e-151 purD 6.3.4.13 F Belongs to the GARS family
PKNEJCON_01174 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PKNEJCON_01175 1.1e-198 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PKNEJCON_01176 4.2e-175 1.1.1.169 H Ketopantoate reductase
PKNEJCON_01177 3.3e-33
PKNEJCON_01178 2.1e-134 J Domain of unknown function (DUF4041)
PKNEJCON_01180 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PKNEJCON_01181 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PKNEJCON_01182 3.1e-69 argR K Regulates arginine biosynthesis genes
PKNEJCON_01183 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PKNEJCON_01184 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PKNEJCON_01185 3.5e-79 S Protein of unknown function (DUF3021)
PKNEJCON_01186 1.1e-69 K LytTr DNA-binding domain
PKNEJCON_01188 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PKNEJCON_01190 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PKNEJCON_01191 8.6e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
PKNEJCON_01192 1.3e-224 cinA 3.5.1.42 S Belongs to the CinA family
PKNEJCON_01193 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PKNEJCON_01194 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
PKNEJCON_01195 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PKNEJCON_01196 3.2e-220 vicK 2.7.13.3 T Histidine kinase
PKNEJCON_01197 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
PKNEJCON_01198 1.3e-57 S Protein of unknown function (DUF454)
PKNEJCON_01199 6.7e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
PKNEJCON_01200 6.6e-145 yidA S hydrolases of the HAD superfamily
PKNEJCON_01201 1.5e-142 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
PKNEJCON_01202 2.2e-66 ywiB S Domain of unknown function (DUF1934)
PKNEJCON_01203 0.0 pacL 3.6.3.8 P cation transport ATPase
PKNEJCON_01204 1.6e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PKNEJCON_01205 4.7e-154 yjjH S Calcineurin-like phosphoesterase
PKNEJCON_01206 1e-204 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PKNEJCON_01207 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PKNEJCON_01208 3.2e-124 ftsE D cell division ATP-binding protein FtsE
PKNEJCON_01209 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PKNEJCON_01210 7.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
PKNEJCON_01211 1.8e-175 yubA S permease
PKNEJCON_01212 7e-223 G COG0457 FOG TPR repeat
PKNEJCON_01213 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PKNEJCON_01215 1.9e-86 sigH K DNA-templated transcription, initiation
PKNEJCON_01216 5.8e-138 ykuT M mechanosensitive ion channel
PKNEJCON_01217 1.5e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PKNEJCON_01218 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PKNEJCON_01219 1.4e-308 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PKNEJCON_01220 3.8e-84 XK27_03960 S Protein of unknown function (DUF3013)
PKNEJCON_01221 4.9e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
PKNEJCON_01222 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
PKNEJCON_01223 1.9e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PKNEJCON_01224 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PKNEJCON_01225 9.1e-83 nrdI F Belongs to the NrdI family
PKNEJCON_01226 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PKNEJCON_01227 1.8e-72 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PKNEJCON_01228 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PKNEJCON_01229 4.3e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PKNEJCON_01230 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
PKNEJCON_01231 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PKNEJCON_01232 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PKNEJCON_01233 3.1e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PKNEJCON_01234 5.8e-55 S TM2 domain
PKNEJCON_01235 2.7e-43
PKNEJCON_01237 2.4e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PKNEJCON_01238 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PKNEJCON_01239 1.4e-142 cmpC S abc transporter atp-binding protein
PKNEJCON_01240 0.0 WQ51_06230 S ABC transporter
PKNEJCON_01241 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PKNEJCON_01242 5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PKNEJCON_01243 9.3e-144 cdsA 2.7.7.41 S Belongs to the CDS family
PKNEJCON_01244 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PKNEJCON_01245 5.9e-47 yajC U protein transport
PKNEJCON_01246 6.1e-126 yeeN K transcriptional regulatory protein
PKNEJCON_01247 2.8e-280 V ABC transporter
PKNEJCON_01248 1.4e-153 Z012_04635 K sequence-specific DNA binding
PKNEJCON_01249 2.6e-97 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
PKNEJCON_01251 1.7e-287 S Protein of unknown function (DUF3114)
PKNEJCON_01252 2.5e-98 2.3.1.128 K Acetyltransferase GNAT Family
PKNEJCON_01253 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PKNEJCON_01254 1.8e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
PKNEJCON_01255 6.4e-178 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
PKNEJCON_01256 1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PKNEJCON_01257 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PKNEJCON_01258 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PKNEJCON_01259 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PKNEJCON_01260 3.5e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PKNEJCON_01261 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PKNEJCON_01262 1.7e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PKNEJCON_01263 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PKNEJCON_01264 1.4e-217 ywbD 2.1.1.191 J Methyltransferase
PKNEJCON_01265 6.8e-119 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PKNEJCON_01266 4.2e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PKNEJCON_01267 2.9e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PKNEJCON_01268 9.9e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PKNEJCON_01269 7.7e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PKNEJCON_01270 4.2e-53 yheA S Belongs to the UPF0342 family
PKNEJCON_01271 3.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PKNEJCON_01272 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PKNEJCON_01273 6.1e-77 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PKNEJCON_01274 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
PKNEJCON_01275 2.5e-248 msrR K Transcriptional regulator
PKNEJCON_01276 2.7e-150 ydiA P C4-dicarboxylate transporter malic acid transport
PKNEJCON_01277 4.5e-202 I acyl-CoA dehydrogenase
PKNEJCON_01278 2e-97 mip S hydroperoxide reductase activity
PKNEJCON_01279 1.6e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PKNEJCON_01280 7.6e-168 D nuclear chromosome segregation
PKNEJCON_01281 2.6e-135 yejC S cyclic nucleotide-binding protein
PKNEJCON_01282 3.8e-162 rapZ S Displays ATPase and GTPase activities
PKNEJCON_01283 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PKNEJCON_01284 2.2e-160 whiA K May be required for sporulation
PKNEJCON_01285 2.6e-274 pepD E Dipeptidase
PKNEJCON_01286 2.8e-143 XK27_10720 D peptidase activity
PKNEJCON_01287 5.2e-284 adcA P Belongs to the bacterial solute-binding protein 9 family
PKNEJCON_01288 2.6e-09
PKNEJCON_01290 2.5e-170 yeiH S Membrane
PKNEJCON_01291 3.5e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
PKNEJCON_01292 8.4e-165 cpsY K Transcriptional regulator
PKNEJCON_01293 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PKNEJCON_01294 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
PKNEJCON_01295 3.1e-105 artQ P ABC transporter (Permease
PKNEJCON_01296 1.7e-111 glnQ 3.6.3.21 E abc transporter atp-binding protein
PKNEJCON_01297 4.6e-157 aatB ET ABC transporter substrate-binding protein
PKNEJCON_01298 1.9e-158 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PKNEJCON_01299 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PKNEJCON_01300 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PKNEJCON_01301 1.9e-232 rodA D Belongs to the SEDS family
PKNEJCON_01302 4.2e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PKNEJCON_01303 1.8e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PKNEJCON_01304 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PKNEJCON_01305 2.8e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PKNEJCON_01306 3.3e-124 Q Methyltransferase domain
PKNEJCON_01307 1.2e-65 GnaT 2.5.1.16 K acetyltransferase
PKNEJCON_01308 2.3e-16 M Putative cell wall binding repeat
PKNEJCON_01309 0.0 S dextransucrase activity
PKNEJCON_01310 0.0 S dextransucrase activity
PKNEJCON_01311 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PKNEJCON_01312 1.4e-241 S dextransucrase activity
PKNEJCON_01313 2.1e-95 L Transposase
PKNEJCON_01314 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
PKNEJCON_01315 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
PKNEJCON_01316 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PKNEJCON_01317 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PKNEJCON_01318 3.7e-73 ylbF S Belongs to the UPF0342 family
PKNEJCON_01319 4.2e-46 ylbG S UPF0298 protein
PKNEJCON_01320 2.6e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
PKNEJCON_01321 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
PKNEJCON_01322 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
PKNEJCON_01323 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
PKNEJCON_01324 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
PKNEJCON_01325 3.5e-112 acuB S CBS domain
PKNEJCON_01326 2.4e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PKNEJCON_01327 4.2e-107 yvyE 3.4.13.9 S YigZ family
PKNEJCON_01328 9.4e-250 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PKNEJCON_01329 1.1e-81 comFC K competence protein
PKNEJCON_01330 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PKNEJCON_01331 4e-84 2.7.13.3 T Histidine kinase
PKNEJCON_01332 5.9e-36 K Helix-turn-helix
PKNEJCON_01333 1.7e-39 D LPXTG cell wall anchor motif
PKNEJCON_01335 7e-93 amiB 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
PKNEJCON_01337 3.5e-69
PKNEJCON_01338 7.8e-73 S AAA domain, putative AbiEii toxin, Type IV TA system
PKNEJCON_01339 9.1e-37 S Psort location Cytoplasmic, score
PKNEJCON_01340 6.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PKNEJCON_01341 2.9e-125 gntR1 K transcriptional
PKNEJCON_01342 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PKNEJCON_01343 6.5e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PKNEJCON_01344 1.3e-85
PKNEJCON_01345 6.6e-90 niaR S small molecule binding protein (contains 3H domain)
PKNEJCON_01346 4e-127 K DNA-binding helix-turn-helix protein
PKNEJCON_01347 6.8e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
PKNEJCON_01349 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PKNEJCON_01350 2.6e-95 ypmS S Protein conserved in bacteria
PKNEJCON_01351 3.4e-155 ypmR E COG2755 Lysophospholipase L1 and related esterases
PKNEJCON_01352 1.7e-148 DegV S DegV family
PKNEJCON_01353 1.8e-301 recN L May be involved in recombinational repair of damaged DNA
PKNEJCON_01354 8.3e-73 argR K Regulates arginine biosynthesis genes
PKNEJCON_01355 1.9e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PKNEJCON_01356 4.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PKNEJCON_01357 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PKNEJCON_01358 1.1e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PKNEJCON_01360 1.7e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PKNEJCON_01361 1.3e-125 dnaD
PKNEJCON_01362 6.7e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PKNEJCON_01363 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PKNEJCON_01364 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
PKNEJCON_01365 3.2e-95 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
PKNEJCON_01366 1.4e-161 XK27_05670 S Putative esterase
PKNEJCON_01367 2.7e-153 XK27_05675 S Esterase
PKNEJCON_01368 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
PKNEJCON_01369 3e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
PKNEJCON_01370 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
PKNEJCON_01371 0.0 uup S abc transporter atp-binding protein
PKNEJCON_01372 1.6e-39 MA20_06245 S yiaA/B two helix domain
PKNEJCON_01373 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
PKNEJCON_01374 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PKNEJCON_01375 2.3e-150 cobQ S glutamine amidotransferase
PKNEJCON_01376 1.2e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
PKNEJCON_01377 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PKNEJCON_01378 3.8e-163 ybbR S Protein conserved in bacteria
PKNEJCON_01379 2.2e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PKNEJCON_01380 1.3e-64 gtrA S GtrA-like protein
PKNEJCON_01381 6.9e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
PKNEJCON_01382 4.9e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PKNEJCON_01383 3.7e-143 zupT P Mediates zinc uptake. May also transport other divalent cations
PKNEJCON_01384 3.5e-202 yurR 1.4.5.1 E oxidoreductase
PKNEJCON_01385 1.8e-256 S phospholipase Carboxylesterase
PKNEJCON_01386 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PKNEJCON_01387 3.5e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PKNEJCON_01388 2.8e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PKNEJCON_01390 5.8e-31 KT response to antibiotic
PKNEJCON_01391 6.5e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
PKNEJCON_01392 1.8e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
PKNEJCON_01393 2.3e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PKNEJCON_01394 1.5e-115 ylfI S tigr01906
PKNEJCON_01395 3.5e-137 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
PKNEJCON_01396 4e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PKNEJCON_01397 1.4e-38 XK27_08085
PKNEJCON_01398 3.2e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PKNEJCON_01399 2.4e-181 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PKNEJCON_01400 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PKNEJCON_01401 1.3e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PKNEJCON_01402 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PKNEJCON_01403 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PKNEJCON_01404 1e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PKNEJCON_01405 1.5e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PKNEJCON_01406 1.4e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PKNEJCON_01407 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PKNEJCON_01409 7.6e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
PKNEJCON_01410 6.6e-142 P molecular chaperone
PKNEJCON_01411 1.5e-95 S Carbohydrate-binding domain-containing protein Cthe_2159
PKNEJCON_01412 1e-179 XK27_08075 M glycosyl transferase family 2
PKNEJCON_01414 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PKNEJCON_01416 1.9e-124 V abc transporter atp-binding protein
PKNEJCON_01417 0.0 V ABC transporter (Permease
PKNEJCON_01418 1.2e-124 K transcriptional regulator, MerR family
PKNEJCON_01419 4.9e-105 dnaQ 2.7.7.7 L DNA polymerase III
PKNEJCON_01420 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
PKNEJCON_01421 9.6e-64 XK27_02560 S cog cog2151
PKNEJCON_01422 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PKNEJCON_01423 8.8e-223 ytfP S Flavoprotein
PKNEJCON_01425 7.6e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PKNEJCON_01426 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
PKNEJCON_01427 3.2e-176 ecsB U Bacterial ABC transporter protein EcsB
PKNEJCON_01428 2.2e-131 ecsA V abc transporter atp-binding protein
PKNEJCON_01429 1.1e-264 M Putative cell wall binding repeat
PKNEJCON_01430 1.6e-237 tcdB S dextransucrase activity
PKNEJCON_01431 0.0 S dextransucrase activity
PKNEJCON_01432 6.4e-105 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PKNEJCON_01433 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PKNEJCON_01434 0.0 M Putative cell wall binding repeat
PKNEJCON_01435 0.0 S dextransucrase activity
PKNEJCON_01436 2.1e-19 S dextransucrase activity
PKNEJCON_01437 1e-12 S dextransucrase activity
PKNEJCON_01439 2.3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PKNEJCON_01440 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PKNEJCON_01441 6.1e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
PKNEJCON_01442 1.4e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PKNEJCON_01443 3.9e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PKNEJCON_01444 1.8e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
PKNEJCON_01445 3.1e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PKNEJCON_01446 4.4e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
PKNEJCON_01447 3.5e-120 yujD V lipoprotein transporter activity
PKNEJCON_01448 0.0 S bacteriocin-associated integral membrane protein
PKNEJCON_01449 2.1e-19 S Bacteriocin (Lactococcin_972)
PKNEJCON_01450 1.7e-57
PKNEJCON_01451 0.0 ctpE P E1-E2 ATPase
PKNEJCON_01452 4.7e-48
PKNEJCON_01453 1.2e-110 cps4C M biosynthesis protein
PKNEJCON_01454 1.4e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
PKNEJCON_01455 6.1e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
PKNEJCON_01456 7.6e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
PKNEJCON_01457 2.3e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
PKNEJCON_01458 1.6e-174 clcA_2 P Chloride transporter, ClC family
PKNEJCON_01459 1.1e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PKNEJCON_01460 2.9e-96 S Protein of unknown function (DUF1697)
PKNEJCON_01461 2.7e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PKNEJCON_01462 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PKNEJCON_01463 9.7e-253 V Glucan-binding protein C
PKNEJCON_01464 1.6e-12 V Glucan-binding protein C
PKNEJCON_01465 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PKNEJCON_01466 2.2e-146 ycdO P periplasmic lipoprotein involved in iron transport
PKNEJCON_01467 6.2e-232 ycdB P peroxidase
PKNEJCON_01468 2.2e-288 ywbL P COG0672 High-affinity Fe2 Pb2 permease
PKNEJCON_01469 6e-118 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PKNEJCON_01470 9.5e-23 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PKNEJCON_01471 4.7e-213 msmX P Belongs to the ABC transporter superfamily
PKNEJCON_01472 9.8e-152 malG P ABC transporter (Permease
PKNEJCON_01473 4.4e-250 malF P ABC transporter (Permease
PKNEJCON_01474 3.9e-229 malX G ABC transporter
PKNEJCON_01475 4.1e-38 S granule-associated protein
PKNEJCON_01476 2.3e-286 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PKNEJCON_01477 7.2e-198 S hmm pf01594
PKNEJCON_01478 1.1e-107 G Belongs to the phosphoglycerate mutase family
PKNEJCON_01479 2.8e-108 G Belongs to the phosphoglycerate mutase family
PKNEJCON_01480 6.3e-108 pgm G Belongs to the phosphoglycerate mutase family
PKNEJCON_01481 1.1e-150 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PKNEJCON_01483 4.8e-180 wbbI M transferase activity, transferring glycosyl groups
PKNEJCON_01484 3.7e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
PKNEJCON_01485 7.5e-245 epsU S Polysaccharide biosynthesis protein
PKNEJCON_01486 1.1e-105 cps3F
PKNEJCON_01487 3.2e-141 M Glycosyltransferase like family 2
PKNEJCON_01488 4.4e-60 M Glycosyltransferase, group 2 family protein
PKNEJCON_01489 3.6e-297 V abc transporter atp-binding protein
PKNEJCON_01490 0.0 V abc transporter atp-binding protein
PKNEJCON_01491 6.1e-192 XK27_10075 S abc transporter atp-binding protein
PKNEJCON_01492 1.1e-09
PKNEJCON_01494 1.9e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PKNEJCON_01495 2.1e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PKNEJCON_01496 4.8e-171 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PKNEJCON_01497 3.8e-154 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PKNEJCON_01498 2.4e-101 GBS0088 J protein conserved in bacteria
PKNEJCON_01499 1.2e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PKNEJCON_01500 3e-126 E Alpha beta hydrolase
PKNEJCON_01502 1.2e-194 ald 1.4.1.1 C Belongs to the AlaDH PNT family
PKNEJCON_01503 1.3e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PKNEJCON_01504 2.6e-138 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PKNEJCON_01505 3.9e-114 S VIT family
PKNEJCON_01506 7.4e-138 deoD_1 2.4.2.3 F Phosphorylase superfamily
PKNEJCON_01513 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PKNEJCON_01514 1.9e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PKNEJCON_01515 5.5e-36 XK27_02060 S Transglycosylase associated protein
PKNEJCON_01516 2.6e-71 badR K Transcriptional regulator, marr family
PKNEJCON_01517 3.2e-95 S reductase
PKNEJCON_01519 2e-288 ahpF O alkyl hydroperoxide reductase
PKNEJCON_01520 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
PKNEJCON_01521 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
PKNEJCON_01522 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PKNEJCON_01523 1.6e-82 S Putative small multi-drug export protein
PKNEJCON_01524 1.8e-75 ctsR K Belongs to the CtsR family
PKNEJCON_01525 0.0 clpC O Belongs to the ClpA ClpB family
PKNEJCON_01526 1.3e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PKNEJCON_01527 1.6e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PKNEJCON_01528 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PKNEJCON_01529 1.4e-139 S SseB protein N-terminal domain
PKNEJCON_01530 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
PKNEJCON_01532 1.2e-255 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PKNEJCON_01533 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PKNEJCON_01535 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PKNEJCON_01536 6e-91 yacP S RNA-binding protein containing a PIN domain
PKNEJCON_01537 1.2e-152 degV S DegV family
PKNEJCON_01539 5.1e-22 K Transcriptional
PKNEJCON_01540 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PKNEJCON_01541 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
PKNEJCON_01542 2.4e-19
PKNEJCON_01543 3.4e-29 K Helix-turn-helix domain
PKNEJCON_01545 2e-149 srtB 3.4.22.70 S Sortase family
PKNEJCON_01546 1.1e-233 capA M Bacterial capsule synthesis protein
PKNEJCON_01547 6.1e-39 gcvR T UPF0237 protein
PKNEJCON_01548 2.3e-243 XK27_08635 S UPF0210 protein
PKNEJCON_01549 1.2e-131 ais G Phosphoglycerate mutase
PKNEJCON_01550 1.4e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PKNEJCON_01551 3.6e-100 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
PKNEJCON_01552 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PKNEJCON_01553 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PKNEJCON_01554 6e-303 dnaK O Heat shock 70 kDa protein
PKNEJCON_01555 4.9e-103 thiJ-2 3.5.1.124 S DJ-1/PfpI family
PKNEJCON_01556 1.8e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PKNEJCON_01557 3.8e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PKNEJCON_01558 3.1e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
PKNEJCON_01559 7.4e-80 hmpT S cog cog4720
PKNEJCON_01561 4.1e-283 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PKNEJCON_01562 5.5e-31 S PQ loop repeat
PKNEJCON_01563 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
PKNEJCON_01564 1.9e-278 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
PKNEJCON_01565 1e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
PKNEJCON_01566 1.1e-57
PKNEJCON_01567 1.2e-215 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PKNEJCON_01568 2.7e-64
PKNEJCON_01569 2.3e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PKNEJCON_01570 1.4e-98 yqeG S hydrolase of the HAD superfamily
PKNEJCON_01571 1.3e-212 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PKNEJCON_01572 7.7e-49 yhbY J RNA-binding protein
PKNEJCON_01573 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PKNEJCON_01574 5.9e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PKNEJCON_01575 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PKNEJCON_01576 4.2e-138 yqeM Q Methyltransferase domain protein
PKNEJCON_01577 5.2e-08 sraP UW domain, Protein
PKNEJCON_01578 8.3e-25
PKNEJCON_01579 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PKNEJCON_01580 0.0 3.5.1.28 M domain protein
PKNEJCON_01581 2.3e-136 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
PKNEJCON_01582 5.1e-66 gltJ P ABC transporter (Permease
PKNEJCON_01583 2.9e-111 tcyB_2 P ABC transporter (permease)
PKNEJCON_01584 1.4e-153 endA F DNA RNA non-specific endonuclease
PKNEJCON_01585 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
PKNEJCON_01586 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PKNEJCON_01588 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PKNEJCON_01589 2.2e-135 G Domain of unknown function (DUF4832)
PKNEJCON_01590 9.2e-84 S membrane
PKNEJCON_01591 6.7e-96 P VTC domain
PKNEJCON_01592 1.3e-222 cotH M CotH kinase protein
PKNEJCON_01593 5.4e-182 pelG M Putative exopolysaccharide Exporter (EPS-E)
PKNEJCON_01594 1.1e-269 pelF GT4 M Domain of unknown function (DUF3492)
PKNEJCON_01595 3.8e-122 S Uncharacterised protein conserved in bacteria (DUF2194)
PKNEJCON_01596 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PKNEJCON_01597 1.5e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PKNEJCON_01598 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PKNEJCON_01599 4e-142 purR 2.4.2.7 F operon repressor
PKNEJCON_01600 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
PKNEJCON_01601 2.5e-170 rmuC S RmuC domain protein
PKNEJCON_01602 1.2e-114 thiN 2.7.6.2 H thiamine pyrophosphokinase
PKNEJCON_01603 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PKNEJCON_01604 2.4e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PKNEJCON_01606 1.1e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PKNEJCON_01607 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PKNEJCON_01608 1.2e-143 tatD L Hydrolase, tatd
PKNEJCON_01609 2.7e-73 yccU S CoA-binding protein
PKNEJCON_01610 2.4e-50 trxA O Belongs to the thioredoxin family
PKNEJCON_01611 5.2e-175 S hydrolase
PKNEJCON_01612 8.4e-23
PKNEJCON_01613 1.4e-141 M LysM domain
PKNEJCON_01614 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PKNEJCON_01615 2.2e-11
PKNEJCON_01616 0.0 L helicase
PKNEJCON_01617 2.1e-64 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
PKNEJCON_01618 4.3e-12
PKNEJCON_01619 1.1e-232 mntH P H( )-stimulated, divalent metal cation uptake system
PKNEJCON_01620 1.1e-33 XK27_12190 S protein conserved in bacteria
PKNEJCON_01622 3.2e-87 bioY S biotin synthase
PKNEJCON_01623 8.3e-251 yegQ O Peptidase U32
PKNEJCON_01624 1.5e-177 yegQ O Peptidase U32
PKNEJCON_01626 3e-67 ytxH S General stress protein
PKNEJCON_01627 3.1e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PKNEJCON_01628 5.3e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PKNEJCON_01629 2e-166 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PKNEJCON_01630 8.4e-41 pspC KT PspC domain
PKNEJCON_01631 0.0 yhgF K Transcriptional accessory protein
PKNEJCON_01633 4.2e-156 XK27_03015 S permease
PKNEJCON_01634 9.9e-149 ycgQ S TIGR03943 family
PKNEJCON_01635 3.2e-287 sulP P Sulfate permease and related transporters (MFS superfamily)
PKNEJCON_01636 1.2e-103
PKNEJCON_01637 2.4e-118 estA E GDSL-like Lipase/Acylhydrolase
PKNEJCON_01638 4.4e-93 S CAAX protease self-immunity
PKNEJCON_01639 5.5e-51
PKNEJCON_01641 3.7e-63 yqeB S Pyrimidine dimer DNA glycosylase
PKNEJCON_01642 8.3e-61 S Protein of unknown function (DUF1722)
PKNEJCON_01643 1e-19 S Bacterial lipoprotein
PKNEJCON_01644 4.4e-10
PKNEJCON_01645 4.1e-125 V CAAX protease self-immunity
PKNEJCON_01646 1.7e-48
PKNEJCON_01647 3.5e-123 ybbA S Putative esterase
PKNEJCON_01648 5.5e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PKNEJCON_01649 5.4e-133 fecE 3.6.3.34 HP ABC transporter
PKNEJCON_01650 2.7e-159 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PKNEJCON_01651 1.9e-122 V CAAX protease self-immunity
PKNEJCON_01652 3.1e-153 S Domain of unknown function (DUF4300)
PKNEJCON_01653 1.2e-94 tetR K transcriptional regulator
PKNEJCON_01654 6.8e-296 norB P Major facilitator superfamily
PKNEJCON_01655 7.8e-20 S Domain of unknown function (DUF4767)
PKNEJCON_01657 1e-108 cutC P Participates in the control of copper homeostasis
PKNEJCON_01658 5.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
PKNEJCON_01659 5.1e-148 yitS S EDD domain protein, DegV family
PKNEJCON_01660 3.7e-205 yeaN P transporter
PKNEJCON_01661 5.8e-132 S Domain of unknown function (DUF4336)
PKNEJCON_01662 1.2e-130 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PKNEJCON_01663 1.1e-56 potC P ABC-type spermidine putrescine transport system, permease component II
PKNEJCON_01664 4.4e-205 potD P spermidine putrescine ABC transporter
PKNEJCON_01665 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
PKNEJCON_01666 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
PKNEJCON_01667 9.8e-158 GK ROK family
PKNEJCON_01668 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PKNEJCON_01669 3.1e-101 wecD M Acetyltransferase (GNAT) domain
PKNEJCON_01670 4.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PKNEJCON_01671 1.6e-72 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
PKNEJCON_01672 1.6e-58 arsC 1.20.4.1 P Belongs to the ArsC family
PKNEJCON_01674 1e-55 lrgA S Effector of murein hydrolase LrgA
PKNEJCON_01675 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PKNEJCON_01676 1.3e-94 3.1.3.18 S IA, variant 1
PKNEJCON_01677 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PKNEJCON_01678 8e-191 tcsA S membrane
PKNEJCON_01679 1.1e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PKNEJCON_01680 7.9e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PKNEJCON_01681 1e-229 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PKNEJCON_01682 5.4e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
PKNEJCON_01683 1e-170 coaA 2.7.1.33 F Pantothenic acid kinase
PKNEJCON_01684 1e-29 rpsT J Binds directly to 16S ribosomal RNA
PKNEJCON_01685 2.3e-241 T PhoQ Sensor
PKNEJCON_01686 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PKNEJCON_01687 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PKNEJCON_01688 1e-114 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
PKNEJCON_01689 2e-89 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PKNEJCON_01690 8.3e-37 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PKNEJCON_01691 1.6e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PKNEJCON_01692 7.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PKNEJCON_01693 2.7e-37 ysdA L Membrane
PKNEJCON_01694 5.6e-277 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PKNEJCON_01695 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PKNEJCON_01696 0.0 dnaE 2.7.7.7 L DNA polymerase
PKNEJCON_01697 2.1e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PKNEJCON_01698 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PKNEJCON_01699 5.8e-83 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PKNEJCON_01700 2.6e-305 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PKNEJCON_01701 1.5e-86 ytsP 1.8.4.14 T GAF domain-containing protein
PKNEJCON_01702 1.6e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PKNEJCON_01703 6.5e-21 WQ51_02665 S Protein of unknown function (DUF3042)
PKNEJCON_01704 6.6e-08
PKNEJCON_01705 5.6e-132 K cell adhesion
PKNEJCON_01706 5.6e-77 S Phage integrase family
PKNEJCON_01708 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PKNEJCON_01709 1.7e-216 XK27_05110 P Chloride transporter ClC family
PKNEJCON_01710 4.2e-38 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
PKNEJCON_01711 1.3e-279 clcA P Chloride transporter, ClC family
PKNEJCON_01712 1e-75 fld C Flavodoxin
PKNEJCON_01713 2.6e-150 rarD S Transporter
PKNEJCON_01714 7e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PKNEJCON_01715 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PKNEJCON_01716 1.6e-128 yxkH G deacetylase
PKNEJCON_01717 1.3e-207 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PKNEJCON_01718 7.4e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PKNEJCON_01719 8.6e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PKNEJCON_01720 9.7e-186 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PKNEJCON_01721 3.3e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
PKNEJCON_01722 1.2e-143 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PKNEJCON_01723 2.9e-84 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
PKNEJCON_01724 9.7e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PKNEJCON_01725 1.4e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PKNEJCON_01726 5.2e-72 marR K Transcriptional regulator, MarR family
PKNEJCON_01727 8.2e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
PKNEJCON_01728 2.8e-114 S HAD hydrolase, family IA, variant 3
PKNEJCON_01729 1.8e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
PKNEJCON_01730 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
PKNEJCON_01731 1.4e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PKNEJCON_01732 1.4e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
PKNEJCON_01733 7.8e-102 ygaC J Belongs to the UPF0374 family
PKNEJCON_01734 1.9e-104 S Domain of unknown function (DUF1803)
PKNEJCON_01735 3.9e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
PKNEJCON_01738 3.3e-220 S membrane
PKNEJCON_01739 8.3e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PKNEJCON_01740 1.1e-292 nptA P COG1283 Na phosphate symporter
PKNEJCON_01741 4.7e-114 3.4.17.14, 3.5.1.28 NU amidase activity
PKNEJCON_01742 1.2e-81 S Bacterial inner membrane protein
PKNEJCON_01743 3.7e-143 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
PKNEJCON_01744 3.5e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
PKNEJCON_01745 1.9e-53 glnB K Belongs to the P(II) protein family
PKNEJCON_01746 3.1e-226 amt P Ammonium Transporter
PKNEJCON_01747 1.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PKNEJCON_01748 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PKNEJCON_01749 4.3e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PKNEJCON_01750 2.9e-208 hpk9 2.7.13.3 T protein histidine kinase activity
PKNEJCON_01751 2.4e-226 2.7.13.3 T protein histidine kinase activity
PKNEJCON_01752 1.8e-119 cas2 2.7.7.7 L CRISPR-associated endoribonuclease Cas2
PKNEJCON_01753 5.5e-17 cas2 2.7.7.7 L CRISPR-associated endoribonuclease Cas2
PKNEJCON_01754 1.4e-78 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PKNEJCON_01755 1.6e-70 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PKNEJCON_01756 6.4e-111 casE S CRISPR system CASCADE complex protein CasE
PKNEJCON_01757 1.5e-132 casD S CRISPR system CASCADE complex protein CasD
PKNEJCON_01758 2.1e-183 casC L CT1975-like protein
PKNEJCON_01759 3.4e-194 iscS 2.8.1.7 E Cysteine desulfurase
PKNEJCON_01760 8.2e-60 XK27_04120 S Putative amino acid metabolism
PKNEJCON_01761 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PKNEJCON_01762 8.2e-128 puuD T peptidase C26
PKNEJCON_01763 1.3e-114 radC E Belongs to the UPF0758 family
PKNEJCON_01764 1.5e-305 rgpF M Rhamnan synthesis protein F
PKNEJCON_01765 2.1e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PKNEJCON_01766 7.5e-141 rgpC GM Transport permease protein
PKNEJCON_01767 1.6e-171 rgpB GT2 M Glycosyltransferase, group 2 family protein
PKNEJCON_01768 3.3e-222 rgpA GT4 M Domain of unknown function (DUF1972)
PKNEJCON_01769 5.1e-98 GT4 M transferase activity, transferring glycosyl groups
PKNEJCON_01770 6.3e-227 mntH P Mn2 and Fe2 transporters of the NRAMP family
PKNEJCON_01771 2.1e-161 ypuA S secreted protein
PKNEJCON_01772 1.1e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
PKNEJCON_01773 3e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
PKNEJCON_01774 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PKNEJCON_01775 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PKNEJCON_01776 1.4e-256 noxE P NADH oxidase
PKNEJCON_01777 2.8e-182 yfmM S abc transporter atp-binding protein
PKNEJCON_01778 3.9e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PKNEJCON_01779 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PKNEJCON_01780 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
PKNEJCON_01781 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PKNEJCON_01782 4.5e-291
PKNEJCON_01783 5.4e-215 dcm 2.1.1.37 H cytosine-specific methyltransferase
PKNEJCON_01786 6.3e-48
PKNEJCON_01787 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PKNEJCON_01788 1.1e-23 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PKNEJCON_01789 3.5e-39 ynzC S UPF0291 protein
PKNEJCON_01790 1.5e-250 cycA E permease
PKNEJCON_01791 1.9e-09 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PKNEJCON_01792 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PKNEJCON_01793 3e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PKNEJCON_01796 1.2e-66 K Helix-turn-helix
PKNEJCON_01798 1.2e-166 fhuR K transcriptional regulator (lysR family)
PKNEJCON_01799 1.3e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PKNEJCON_01800 9.4e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PKNEJCON_01801 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PKNEJCON_01802 8.1e-222 pyrP F uracil Permease
PKNEJCON_01803 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PKNEJCON_01804 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
PKNEJCON_01805 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
PKNEJCON_01806 1.5e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
PKNEJCON_01807 6.8e-181 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PKNEJCON_01808 2.6e-121 macB V ABC transporter, ATP-binding protein
PKNEJCON_01809 1.6e-211 V permease protein
PKNEJCON_01810 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PKNEJCON_01811 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PKNEJCON_01812 7.5e-19
PKNEJCON_01813 7.9e-63 traG U COG3505 Type IV secretory pathway, VirD4 components
PKNEJCON_01814 3.2e-104 XK27_00530 M CHAP domain protein
PKNEJCON_01815 1e-102 abiGI K Transcriptional regulator, AbiEi antitoxin
PKNEJCON_01816 2.1e-272 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
PKNEJCON_01817 0.0 mdlB V abc transporter atp-binding protein
PKNEJCON_01818 0.0 lmrA V abc transporter atp-binding protein
PKNEJCON_01819 1.7e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PKNEJCON_01820 1.4e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PKNEJCON_01821 1.9e-210 T signal transduction protein with a C-terminal ATPase domain
PKNEJCON_01822 2e-129 rr02 KT response regulator
PKNEJCON_01823 1.4e-164 V ABC transporter
PKNEJCON_01824 3.8e-120 sagI S ABC-2 type transporter
PKNEJCON_01825 6.9e-197 yceA S Belongs to the UPF0176 family
PKNEJCON_01826 1.6e-28 XK27_00085 K Transcriptional
PKNEJCON_01827 0.0 XK27_10035 V abc transporter atp-binding protein
PKNEJCON_01828 1.8e-288 yfiB1 V abc transporter atp-binding protein
PKNEJCON_01829 3.2e-99 pvaA M lytic transglycosylase activity
PKNEJCON_01830 2.7e-177 ndpA S 37-kD nucleoid-associated bacterial protein
PKNEJCON_01831 3.9e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PKNEJCON_01832 1.1e-104 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PKNEJCON_01833 2.9e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PKNEJCON_01834 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PKNEJCON_01835 8.8e-68 tdk 2.7.1.21 F thymidine kinase
PKNEJCON_01836 2.2e-19
PKNEJCON_01837 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PKNEJCON_01838 3.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PKNEJCON_01839 2.3e-81 ypmB S Protein conserved in bacteria
PKNEJCON_01840 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PKNEJCON_01841 8.3e-119 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PKNEJCON_01842 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
PKNEJCON_01843 8.6e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
PKNEJCON_01844 1.6e-61 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PKNEJCON_01845 1.6e-165 metF 1.5.1.20 E reductase
PKNEJCON_01846 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PKNEJCON_01848 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
PKNEJCON_01849 0.0 3.6.3.8 P cation transport ATPase
PKNEJCON_01850 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
PKNEJCON_01851 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PKNEJCON_01852 3.9e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PKNEJCON_01853 6.6e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PKNEJCON_01854 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PKNEJCON_01855 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PKNEJCON_01856 1.2e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PKNEJCON_01857 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PKNEJCON_01858 1.8e-125 IQ reductase
PKNEJCON_01859 3e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PKNEJCON_01860 7.5e-120 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
PKNEJCON_01861 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PKNEJCON_01862 7e-98 pncA Q isochorismatase
PKNEJCON_01863 8.9e-294 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PKNEJCON_01864 2.8e-216 M lipopolysaccharide 3-alpha-galactosyltransferase activity
PKNEJCON_01865 1.6e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
PKNEJCON_01866 4.4e-191 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PKNEJCON_01867 9.6e-235 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PKNEJCON_01868 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PKNEJCON_01869 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PKNEJCON_01870 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PKNEJCON_01871 2.3e-139 recO L Involved in DNA repair and RecF pathway recombination
PKNEJCON_01872 1.1e-217 araT 2.6.1.1 E Aminotransferase
PKNEJCON_01873 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PKNEJCON_01874 2.1e-83 usp 3.5.1.28 CBM50 S CHAP domain
PKNEJCON_01875 4.8e-80 mreD M rod shape-determining protein MreD
PKNEJCON_01876 1.5e-107 mreC M Involved in formation and maintenance of cell shape

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)