ORF_ID e_value Gene_name EC_number CAZy COGs Description
PIGPPANF_00001 3.4e-56 S Phage derived protein Gp49-like (DUF891)
PIGPPANF_00002 1e-42 K Helix-turn-helix domain
PIGPPANF_00003 9.9e-302 hsdM 2.1.1.72 V type I restriction-modification system
PIGPPANF_00004 5.8e-134 S double-stranded DNA endodeoxyribonuclease activity
PIGPPANF_00005 0.0 2.4.1.21 GT5 M Right handed beta helix region
PIGPPANF_00006 2.2e-166 spd F DNA RNA non-specific endonuclease
PIGPPANF_00007 2.2e-91 lemA S LemA family
PIGPPANF_00008 1.3e-133 htpX O Belongs to the peptidase M48B family
PIGPPANF_00009 2.6e-115 sirR K iron dependent repressor
PIGPPANF_00010 9.5e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
PIGPPANF_00011 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
PIGPPANF_00012 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
PIGPPANF_00013 4.7e-74 S Psort location CytoplasmicMembrane, score
PIGPPANF_00014 8.1e-64 S Domain of unknown function (DUF4430)
PIGPPANF_00015 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PIGPPANF_00016 1.6e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
PIGPPANF_00017 2.7e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
PIGPPANF_00018 6e-170 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
PIGPPANF_00019 8.1e-101 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
PIGPPANF_00020 9e-79 dps P Belongs to the Dps family
PIGPPANF_00021 3.4e-79 perR P Belongs to the Fur family
PIGPPANF_00022 4.2e-27 yqgQ S protein conserved in bacteria
PIGPPANF_00023 1.1e-175 glk 2.7.1.2 G Glucokinase
PIGPPANF_00024 0.0 typA T GTP-binding protein TypA
PIGPPANF_00026 4.8e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PIGPPANF_00027 1.3e-196 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PIGPPANF_00028 2.7e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PIGPPANF_00029 1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PIGPPANF_00030 3.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PIGPPANF_00031 8.1e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PIGPPANF_00032 5e-94 sepF D cell septum assembly
PIGPPANF_00033 1.7e-30 yggT D integral membrane protein
PIGPPANF_00034 6.5e-137 ylmH S conserved protein, contains S4-like domain
PIGPPANF_00035 2.1e-136 divIVA D Cell division initiation protein
PIGPPANF_00036 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PIGPPANF_00037 8.5e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIGPPANF_00038 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIGPPANF_00039 6.5e-34 nrdH O Glutaredoxin
PIGPPANF_00040 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PIGPPANF_00041 3.4e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
PIGPPANF_00042 9.1e-220 icd 1.1.1.42 C Isocitrate dehydrogenase
PIGPPANF_00043 5.1e-38 ptsH G phosphocarrier protein Hpr
PIGPPANF_00044 4.8e-120 liaI S membrane
PIGPPANF_00045 3.4e-74 XK27_02470 K LytTr DNA-binding domain
PIGPPANF_00046 1.3e-302 KT response to antibiotic
PIGPPANF_00047 4.2e-111 yebC M Membrane
PIGPPANF_00048 2.4e-256 XK27_03190 S hydrolases of the HAD superfamily
PIGPPANF_00049 4.4e-169 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PIGPPANF_00051 1.4e-156 K Helix-turn-helix XRE-family like proteins
PIGPPANF_00052 2.8e-280 V ABC transporter transmembrane region
PIGPPANF_00053 2.9e-31 yozG K Transcriptional regulator
PIGPPANF_00057 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PIGPPANF_00058 1.2e-181 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PIGPPANF_00059 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PIGPPANF_00060 2.1e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PIGPPANF_00061 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PIGPPANF_00062 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIGPPANF_00064 6.5e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
PIGPPANF_00065 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
PIGPPANF_00066 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PIGPPANF_00067 7.6e-285 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
PIGPPANF_00068 3.7e-179 scrR K Transcriptional regulator
PIGPPANF_00069 1.3e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PIGPPANF_00070 1.7e-61 yqhY S protein conserved in bacteria
PIGPPANF_00071 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIGPPANF_00072 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
PIGPPANF_00073 9.1e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
PIGPPANF_00075 2.1e-32 blpT
PIGPPANF_00079 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PIGPPANF_00080 1.9e-167 corA P COG0598 Mg2 and Co2 transporters
PIGPPANF_00081 5e-122 XK27_01040 S Protein of unknown function (DUF1129)
PIGPPANF_00083 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PIGPPANF_00084 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIGPPANF_00085 6.1e-31 rpsF J Binds together with S18 to 16S ribosomal RNA
PIGPPANF_00086 2e-104 thiJ-2 3.5.1.124 S DJ-1/PfpI family
PIGPPANF_00087 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PIGPPANF_00088 5e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PIGPPANF_00089 2.6e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
PIGPPANF_00090 7.4e-80 hmpT S cog cog4720
PIGPPANF_00091 7.5e-49 3.2.2.21 S YCII-related domain
PIGPPANF_00092 2.4e-50 K regulation of RNA biosynthetic process
PIGPPANF_00093 1.2e-152 cylA V abc transporter atp-binding protein
PIGPPANF_00094 3e-132 cylB V ABC-2 type transporter
PIGPPANF_00095 1.1e-72 K COG3279 Response regulator of the LytR AlgR family
PIGPPANF_00096 1.7e-30 S Protein of unknown function (DUF3021)
PIGPPANF_00097 3.4e-121 mta K Transcriptional
PIGPPANF_00098 8.1e-120 yhcA V abc transporter atp-binding protein
PIGPPANF_00099 1.7e-205 macB_2 V FtsX-like permease family
PIGPPANF_00100 3.9e-273 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PIGPPANF_00101 7.6e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PIGPPANF_00102 3.1e-72 yhaI S Protein of unknown function (DUF805)
PIGPPANF_00103 1.9e-253 pepC 3.4.22.40 E aminopeptidase
PIGPPANF_00104 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PIGPPANF_00105 2.1e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PIGPPANF_00106 1.1e-92 ypsA S Belongs to the UPF0398 family
PIGPPANF_00107 3.6e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PIGPPANF_00108 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PIGPPANF_00109 9.5e-278 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
PIGPPANF_00110 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
PIGPPANF_00111 4.8e-22
PIGPPANF_00112 5.2e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PIGPPANF_00113 8e-85 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
PIGPPANF_00114 6.7e-292 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PIGPPANF_00115 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIGPPANF_00116 1.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIGPPANF_00117 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PIGPPANF_00118 8.7e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIGPPANF_00119 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
PIGPPANF_00120 3.2e-100 ybhL S Belongs to the BI1 family
PIGPPANF_00121 4.2e-12 ycdA S Domain of unknown function (DUF4352)
PIGPPANF_00122 3.1e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PIGPPANF_00123 4.5e-89 K transcriptional regulator
PIGPPANF_00124 1.6e-36 yneF S UPF0154 protein
PIGPPANF_00125 7.6e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PIGPPANF_00126 5.3e-181 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PIGPPANF_00127 3.3e-97 XK27_09740 S Phosphoesterase
PIGPPANF_00128 7.1e-86 ykuL S CBS domain
PIGPPANF_00129 9.1e-128 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
PIGPPANF_00130 3.4e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PIGPPANF_00131 6.9e-96 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PIGPPANF_00132 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PIGPPANF_00133 1.8e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
PIGPPANF_00134 6e-258 trkH P Cation transport protein
PIGPPANF_00135 9.3e-245 trkA P Potassium transporter peripheral membrane component
PIGPPANF_00136 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PIGPPANF_00137 7.4e-87 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PIGPPANF_00138 1.1e-89 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
PIGPPANF_00139 2.1e-155 K sequence-specific DNA binding
PIGPPANF_00140 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PIGPPANF_00141 3.2e-53 yhaI L Membrane
PIGPPANF_00142 4e-243 S Domain of unknown function (DUF4173)
PIGPPANF_00143 6.8e-95 ureI S AmiS/UreI family transporter
PIGPPANF_00144 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PIGPPANF_00145 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PIGPPANF_00146 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PIGPPANF_00147 6.6e-78 ureE O enzyme active site formation
PIGPPANF_00148 1.1e-127 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PIGPPANF_00149 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PIGPPANF_00150 1.1e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PIGPPANF_00151 2.1e-177 cbiM P PDGLE domain
PIGPPANF_00152 2.4e-136 P cobalt transport protein
PIGPPANF_00153 1.3e-128 cbiO P ABC transporter
PIGPPANF_00154 1.8e-137 ET ABC transporter substrate-binding protein
PIGPPANF_00155 7.8e-163 metQ M Belongs to the NlpA lipoprotein family
PIGPPANF_00156 5.5e-261 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
PIGPPANF_00157 1.5e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PIGPPANF_00158 1.2e-99 metI P ABC transporter (Permease
PIGPPANF_00159 2.2e-208 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PIGPPANF_00160 3.5e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
PIGPPANF_00161 2.3e-93 S UPF0397 protein
PIGPPANF_00162 2.9e-304 ykoD P abc transporter atp-binding protein
PIGPPANF_00163 2.1e-146 cbiQ P cobalt transport
PIGPPANF_00164 1.8e-116 ktrA P COG0569 K transport systems, NAD-binding component
PIGPPANF_00165 9.8e-234 P COG0168 Trk-type K transport systems, membrane components
PIGPPANF_00166 3.2e-127 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
PIGPPANF_00167 3.1e-90 yceD K metal-binding, possibly nucleic acid-binding protein
PIGPPANF_00168 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIGPPANF_00169 7.3e-278 T PhoQ Sensor
PIGPPANF_00170 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PIGPPANF_00171 2.1e-208 dnaB L Replication initiation and membrane attachment
PIGPPANF_00172 2.2e-165 dnaI L Primosomal protein DnaI
PIGPPANF_00173 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PIGPPANF_00174 8e-106
PIGPPANF_00175 2.2e-227 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PIGPPANF_00176 7.2e-62 manO S protein conserved in bacteria
PIGPPANF_00177 1.6e-168 manN G PTS system mannose fructose sorbose family IID component
PIGPPANF_00178 1.2e-117 manM G pts system
PIGPPANF_00179 5.2e-176 manL 2.7.1.191 G pts system
PIGPPANF_00180 1e-66 manO S Protein conserved in bacteria
PIGPPANF_00181 3.6e-163 manN G PTS system mannose fructose sorbose family IID component
PIGPPANF_00182 4.7e-135 manY G pts system
PIGPPANF_00183 6.2e-169 manL 2.7.1.191 G pts system
PIGPPANF_00184 7.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
PIGPPANF_00185 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
PIGPPANF_00186 6.2e-247 pbuO S permease
PIGPPANF_00187 1.2e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
PIGPPANF_00188 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
PIGPPANF_00189 7.7e-193 brpA K Transcriptional
PIGPPANF_00190 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
PIGPPANF_00191 7.1e-196 nusA K Participates in both transcription termination and antitermination
PIGPPANF_00192 1.4e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
PIGPPANF_00193 8e-42 ylxQ J ribosomal protein
PIGPPANF_00194 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PIGPPANF_00195 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PIGPPANF_00196 2.5e-98 yvdD 3.2.2.10 S Belongs to the LOG family
PIGPPANF_00197 5.5e-191 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
PIGPPANF_00198 1.3e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PIGPPANF_00199 2.2e-277 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
PIGPPANF_00200 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
PIGPPANF_00201 3e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
PIGPPANF_00202 3.1e-220 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PIGPPANF_00203 3e-304 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
PIGPPANF_00204 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
PIGPPANF_00205 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PIGPPANF_00206 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PIGPPANF_00207 6.4e-73 ylbF S Belongs to the UPF0342 family
PIGPPANF_00208 1.9e-46 ylbG S UPF0298 protein
PIGPPANF_00209 8.5e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
PIGPPANF_00210 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
PIGPPANF_00211 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
PIGPPANF_00212 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
PIGPPANF_00213 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
PIGPPANF_00214 6.6e-111 acuB S CBS domain
PIGPPANF_00215 1.6e-166 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PIGPPANF_00216 2.2e-108 yvyE 3.4.13.9 S YigZ family
PIGPPANF_00217 4.9e-238 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PIGPPANF_00218 2e-99 comFC K competence protein
PIGPPANF_00219 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PIGPPANF_00221 5.4e-189 nss M transferase activity, transferring glycosyl groups
PIGPPANF_00222 3.6e-16 S Accessory secretory protein Sec, Asp5
PIGPPANF_00223 2.6e-17 S Accessory secretory protein Sec Asp4
PIGPPANF_00224 3.1e-240 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PIGPPANF_00225 5.5e-278 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PIGPPANF_00226 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIGPPANF_00227 6.5e-78 asp3 S Accessory Sec system protein Asp3
PIGPPANF_00228 2.7e-288 asp2 3.4.11.5 S Accessory Sec system protein Asp2
PIGPPANF_00229 3.8e-290 asp1 S Accessory Sec system protein Asp1
PIGPPANF_00230 2.3e-210 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
PIGPPANF_00231 0.0 M family 8
PIGPPANF_00232 0.0 sbcC L ATPase involved in DNA repair
PIGPPANF_00233 5.5e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PIGPPANF_00234 0.0 GM domain, Protein
PIGPPANF_00235 0.0 zmpB M signal peptide protein, YSIRK family
PIGPPANF_00236 8.7e-27 L Transposase (IS116 IS110 IS902 family)
PIGPPANF_00237 8.1e-32 L PFAM transposase IS116 IS110 IS902 family
PIGPPANF_00238 2.4e-90 L Helix-turn-helix domain of transposase family ISL3
PIGPPANF_00239 4.2e-32 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
PIGPPANF_00241 3.6e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIGPPANF_00242 1e-34
PIGPPANF_00243 2.6e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PIGPPANF_00244 9.2e-159 yxeN P ABC transporter (Permease
PIGPPANF_00245 6.1e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
PIGPPANF_00246 5e-10 S Protein of unknown function (DUF4059)
PIGPPANF_00247 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PIGPPANF_00248 2.8e-91 rsmD 2.1.1.171 L Methyltransferase
PIGPPANF_00249 3.9e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PIGPPANF_00250 1.2e-186 ylbL T Belongs to the peptidase S16 family
PIGPPANF_00251 3.9e-181 yhcC S radical SAM protein
PIGPPANF_00252 6.1e-94 ytqB 2.1.1.176 J (SAM)-dependent
PIGPPANF_00254 0.0 yjcE P NhaP-type Na H and K H antiporters
PIGPPANF_00255 6e-25
PIGPPANF_00257 3.9e-142 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
PIGPPANF_00258 1.9e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
PIGPPANF_00259 1.4e-08 MU outer membrane autotransporter barrel domain protein
PIGPPANF_00260 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PIGPPANF_00262 9e-75 XK27_03180 T universal stress protein
PIGPPANF_00263 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
PIGPPANF_00264 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PIGPPANF_00265 2.2e-99 pncA Q isochorismatase
PIGPPANF_00266 1.3e-289 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PIGPPANF_00267 1.3e-216 M lipopolysaccharide 3-alpha-galactosyltransferase activity
PIGPPANF_00268 1.6e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
PIGPPANF_00269 8.3e-190 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PIGPPANF_00270 8.1e-234 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PIGPPANF_00271 1.1e-250 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIGPPANF_00272 1.2e-64
PIGPPANF_00273 1.5e-145 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PIGPPANF_00274 6.7e-98 yqeG S hydrolase of the HAD superfamily
PIGPPANF_00275 1.7e-212 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PIGPPANF_00276 7.7e-49 yhbY J RNA-binding protein
PIGPPANF_00277 1e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PIGPPANF_00278 1.1e-104 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PIGPPANF_00279 3e-87 entB 3.5.1.19 Q Isochorismatase family
PIGPPANF_00280 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PIGPPANF_00281 2.9e-139 yqeM Q Methyltransferase domain protein
PIGPPANF_00282 1.3e-196 ylbM S Belongs to the UPF0348 family
PIGPPANF_00283 1.7e-38 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PIGPPANF_00284 1.6e-44 yoeB S Addiction module toxin, Txe YoeB family
PIGPPANF_00286 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
PIGPPANF_00288 1.6e-103
PIGPPANF_00291 1.1e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PIGPPANF_00292 2.2e-131 ecsA V abc transporter atp-binding protein
PIGPPANF_00293 3.2e-176 ecsB U Bacterial ABC transporter protein EcsB
PIGPPANF_00294 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
PIGPPANF_00295 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PIGPPANF_00297 2.3e-223 ytfP S Flavoprotein
PIGPPANF_00298 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PIGPPANF_00299 9.6e-64 XK27_02560 S cog cog2151
PIGPPANF_00300 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
PIGPPANF_00301 2e-103 dnaQ 2.7.7.7 L DNA polymerase III
PIGPPANF_00302 8.1e-126 K transcriptional regulator, MerR family
PIGPPANF_00303 0.0 V ABC transporter (Permease
PIGPPANF_00304 9.5e-124 V abc transporter atp-binding protein
PIGPPANF_00306 3.9e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PIGPPANF_00307 2e-43
PIGPPANF_00308 2.9e-50
PIGPPANF_00309 3.3e-128 S CAAX amino terminal protease family
PIGPPANF_00310 4.9e-111 cutC P Participates in the control of copper homeostasis
PIGPPANF_00312 2.7e-20 S Domain of unknown function (DUF4767)
PIGPPANF_00313 1.5e-147 S Domain of unknown function (DUF4300)
PIGPPANF_00314 7.7e-116 V CAAX protease self-immunity
PIGPPANF_00315 3.3e-157 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PIGPPANF_00316 4.9e-134 fecE 3.6.3.34 HP ABC transporter
PIGPPANF_00317 6.5e-174 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PIGPPANF_00318 3.7e-120 ybbA S Putative esterase
PIGPPANF_00319 8.2e-157 yegS 2.7.1.107 I Diacylglycerol kinase
PIGPPANF_00320 1.8e-171 S Domain of unknown function (DUF389)
PIGPPANF_00321 5.5e-31 S Membrane
PIGPPANF_00322 7.8e-10 S CsbD-like
PIGPPANF_00323 1.6e-172 pdhD 1.8.1.4 C Dehydrogenase
PIGPPANF_00324 2.8e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
PIGPPANF_00325 4.6e-175 acoB C dehydrogenase E1 component
PIGPPANF_00326 3.8e-144 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PIGPPANF_00327 3.2e-80 Q Methyltransferase domain
PIGPPANF_00328 1.2e-63 K TetR family transcriptional regulator
PIGPPANF_00329 1.2e-46
PIGPPANF_00330 2.8e-126 V CAAX protease self-immunity
PIGPPANF_00331 7.5e-10
PIGPPANF_00332 3.1e-21 M Bacterial lipoprotein
PIGPPANF_00333 1.1e-60 S Protein of unknown function (DUF1722)
PIGPPANF_00334 5.7e-64 yqeB S Pyrimidine dimer DNA glycosylase
PIGPPANF_00336 6.1e-50
PIGPPANF_00337 3.5e-90 S CAAX protease self-immunity
PIGPPANF_00338 3.1e-113 estA E GDSL-like Lipase/Acylhydrolase
PIGPPANF_00339 4.9e-100
PIGPPANF_00340 2.1e-275 sulP P Sulfate permease and related transporters (MFS superfamily)
PIGPPANF_00341 8.4e-148 ycgQ S TIGR03943 family
PIGPPANF_00342 2.3e-154 XK27_03015 S permease
PIGPPANF_00344 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
PIGPPANF_00345 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PIGPPANF_00346 5.3e-226 cinA 3.5.1.42 S Belongs to the CinA family
PIGPPANF_00347 5.1e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
PIGPPANF_00348 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PIGPPANF_00350 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PIGPPANF_00352 1.6e-68 K LytTr DNA-binding domain
PIGPPANF_00353 1.3e-76 S Protein of unknown function (DUF3021)
PIGPPANF_00354 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PIGPPANF_00355 5.3e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PIGPPANF_00356 3.4e-68 argR K Regulates arginine biosynthesis genes
PIGPPANF_00357 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PIGPPANF_00358 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PIGPPANF_00359 6.7e-83
PIGPPANF_00361 1.2e-32
PIGPPANF_00362 4.7e-174 1.1.1.169 H Ketopantoate reductase
PIGPPANF_00363 2.5e-200 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PIGPPANF_00364 1.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PIGPPANF_00365 2.7e-238 purD 6.3.4.13 F Belongs to the GARS family
PIGPPANF_00366 3.9e-156 S CHAP domain
PIGPPANF_00367 2.4e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PIGPPANF_00368 8.3e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PIGPPANF_00369 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PIGPPANF_00370 4.1e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PIGPPANF_00371 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PIGPPANF_00372 2.1e-154 pflB 2.3.1.54 C formate acetyltransferase'
PIGPPANF_00373 6e-143 cah 4.2.1.1 P carbonic anhydrase
PIGPPANF_00374 5.4e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIGPPANF_00376 1.3e-168 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
PIGPPANF_00377 1.1e-136 cppA E CppA N-terminal
PIGPPANF_00378 5.5e-97 V CAAX protease self-immunity
PIGPPANF_00379 2.5e-158 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
PIGPPANF_00380 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PIGPPANF_00381 3.1e-44 spiA K sequence-specific DNA binding
PIGPPANF_00387 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
PIGPPANF_00388 0.0 mdlB V abc transporter atp-binding protein
PIGPPANF_00389 0.0 mdlA V abc transporter atp-binding protein
PIGPPANF_00391 9.7e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
PIGPPANF_00392 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PIGPPANF_00393 9.1e-61 yutD J protein conserved in bacteria
PIGPPANF_00394 1.6e-252 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PIGPPANF_00396 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PIGPPANF_00397 2.4e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PIGPPANF_00398 0.0 ftsI 3.4.16.4 M penicillin-binding protein
PIGPPANF_00399 4e-45 ftsL D cell division protein FtsL
PIGPPANF_00400 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PIGPPANF_00401 6.7e-97
PIGPPANF_00403 2.7e-43 yhaI J Protein of unknown function (DUF805)
PIGPPANF_00404 1.3e-61 yhaI J Protein of unknown function (DUF805)
PIGPPANF_00405 7.3e-15 yhaI J Protein of unknown function (DUF805)
PIGPPANF_00406 9.4e-10 yhaI S Protein of unknown function (DUF805)
PIGPPANF_00407 1.3e-223 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PIGPPANF_00408 3.4e-14 rpmH J Ribosomal protein L34
PIGPPANF_00409 3.8e-99 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
PIGPPANF_00410 1.3e-97 K Transcriptional regulator
PIGPPANF_00411 8.4e-169 jag S RNA-binding protein
PIGPPANF_00412 1.1e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIGPPANF_00413 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PIGPPANF_00414 4.6e-263 argH 4.3.2.1 E Argininosuccinate lyase
PIGPPANF_00415 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PIGPPANF_00416 1.6e-129 fasA KT Response regulator of the LytR AlgR family
PIGPPANF_00417 2.1e-225 fasC T protein histidine kinase activity
PIGPPANF_00418 3.6e-206 hpk9 2.7.13.3 T protein histidine kinase activity
PIGPPANF_00419 2.7e-152 hpk9 2.7.13.3 T protein histidine kinase activity
PIGPPANF_00420 2e-228 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
PIGPPANF_00421 3.7e-271 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PIGPPANF_00422 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PIGPPANF_00423 5.3e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PIGPPANF_00424 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PIGPPANF_00425 1.2e-50 S Protein of unknown function (DUF3397)
PIGPPANF_00426 1e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
PIGPPANF_00427 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
PIGPPANF_00428 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PIGPPANF_00429 4.2e-75 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PIGPPANF_00430 2.1e-76 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PIGPPANF_00431 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
PIGPPANF_00432 1.3e-229 XK27_09615 C reductase
PIGPPANF_00433 1.1e-139 fnt P Formate nitrite transporter
PIGPPANF_00434 6.7e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
PIGPPANF_00435 9.1e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PIGPPANF_00436 1.9e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PIGPPANF_00437 1.8e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
PIGPPANF_00438 5.3e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PIGPPANF_00439 9.7e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PIGPPANF_00440 1.5e-57 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PIGPPANF_00441 1.6e-129 S HAD hydrolase, family IA, variant
PIGPPANF_00442 2e-157 rrmA 2.1.1.187 Q methyltransferase
PIGPPANF_00446 5.1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PIGPPANF_00447 1.9e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIGPPANF_00448 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIGPPANF_00449 1.5e-09 S NTF2 fold immunity protein
PIGPPANF_00450 7.9e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PIGPPANF_00451 2.7e-08 XK27_10305 S Domain of unknown function (DUF4651)
PIGPPANF_00452 3.1e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PIGPPANF_00453 5.2e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PIGPPANF_00454 4e-100 S CAAX amino terminal protease family protein
PIGPPANF_00456 5.8e-107 V CAAX protease self-immunity
PIGPPANF_00457 1.5e-26 lanR K sequence-specific DNA binding
PIGPPANF_00458 2.2e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIGPPANF_00459 2.5e-175 ytxK 2.1.1.72 L DNA methylase
PIGPPANF_00460 1.2e-12 comGF U Putative Competence protein ComGF
PIGPPANF_00461 1.3e-70 comGF U Competence protein ComGF
PIGPPANF_00462 1.1e-15 NU Type II secretory pathway pseudopilin
PIGPPANF_00463 3.5e-68 cglD NU Competence protein
PIGPPANF_00464 2.2e-43 comGC U Required for transformation and DNA binding
PIGPPANF_00465 6.3e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PIGPPANF_00466 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PIGPPANF_00467 1.7e-68 S cog cog4699
PIGPPANF_00468 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIGPPANF_00469 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIGPPANF_00470 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PIGPPANF_00471 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PIGPPANF_00472 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PIGPPANF_00473 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
PIGPPANF_00474 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
PIGPPANF_00475 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PIGPPANF_00476 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
PIGPPANF_00477 1.4e-57 asp S cog cog1302
PIGPPANF_00478 1.6e-225 norN V Mate efflux family protein
PIGPPANF_00479 2.7e-277 thrC 4.2.3.1 E Threonine synthase
PIGPPANF_00482 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PIGPPANF_00483 0.0 pepO 3.4.24.71 O Peptidase family M13
PIGPPANF_00484 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PIGPPANF_00485 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PIGPPANF_00486 2.1e-126 treR K trehalose operon
PIGPPANF_00487 5.1e-96 ywlG S Belongs to the UPF0340 family
PIGPPANF_00490 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
PIGPPANF_00492 4.6e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
PIGPPANF_00493 4.4e-62 rplQ J ribosomal protein l17
PIGPPANF_00494 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIGPPANF_00495 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PIGPPANF_00496 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PIGPPANF_00497 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PIGPPANF_00498 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PIGPPANF_00499 7.3e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PIGPPANF_00500 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PIGPPANF_00501 5.7e-58 rplO J binds to the 23S rRNA
PIGPPANF_00502 1.9e-23 rpmD J ribosomal protein l30
PIGPPANF_00503 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PIGPPANF_00504 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PIGPPANF_00505 2.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PIGPPANF_00506 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PIGPPANF_00507 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIGPPANF_00508 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PIGPPANF_00509 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PIGPPANF_00510 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PIGPPANF_00511 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PIGPPANF_00512 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
PIGPPANF_00513 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PIGPPANF_00514 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PIGPPANF_00515 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PIGPPANF_00516 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PIGPPANF_00517 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PIGPPANF_00518 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PIGPPANF_00519 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
PIGPPANF_00520 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PIGPPANF_00521 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
PIGPPANF_00522 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PIGPPANF_00523 0.0 XK27_09800 I Acyltransferase
PIGPPANF_00524 2.8e-35 XK27_09805 S MORN repeat protein
PIGPPANF_00525 2.6e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIGPPANF_00526 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PIGPPANF_00527 7.2e-89 adk 2.7.4.3 F topology modulation protein
PIGPPANF_00529 4.1e-87 yeiH S membrane
PIGPPANF_00530 2e-42 mccF V LD-carboxypeptidase
PIGPPANF_00531 8.5e-163 L High confidence in function and specificity
PIGPPANF_00532 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PIGPPANF_00533 8.7e-225 rodA D Belongs to the SEDS family
PIGPPANF_00534 6e-244 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PIGPPANF_00535 1.7e-111 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PIGPPANF_00536 1.3e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PIGPPANF_00537 2.2e-134 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PIGPPANF_00538 2.6e-21 Q Methyltransferase domain
PIGPPANF_00539 1.3e-64 GnaT 2.5.1.16 K acetyltransferase
PIGPPANF_00540 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
PIGPPANF_00541 4.9e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PIGPPANF_00542 3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PIGPPANF_00543 6.5e-125 dnaD
PIGPPANF_00544 3.8e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PIGPPANF_00546 2.8e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIGPPANF_00547 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIGPPANF_00548 4e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PIGPPANF_00549 2.5e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PIGPPANF_00550 2.8e-73 argR K Regulates arginine biosynthesis genes
PIGPPANF_00551 8.7e-301 recN L May be involved in recombinational repair of damaged DNA
PIGPPANF_00552 2.6e-144 DegV S DegV family
PIGPPANF_00553 1.2e-155 ypmR E COG2755 Lysophospholipase L1 and related esterases
PIGPPANF_00554 3.4e-95 ypmS S Protein conserved in bacteria
PIGPPANF_00555 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PIGPPANF_00557 2.3e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
PIGPPANF_00561 3e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PIGPPANF_00562 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PIGPPANF_00563 2.9e-10 uvrX 2.7.7.7 L impB/mucB/samB family
PIGPPANF_00564 1.4e-251 cycA E permease
PIGPPANF_00565 1.3e-38 ynzC S UPF0291 protein
PIGPPANF_00566 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PIGPPANF_00567 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PIGPPANF_00568 8.7e-221 S membrane
PIGPPANF_00569 7.5e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PIGPPANF_00570 5.9e-294 nptA P COG1283 Na phosphate symporter
PIGPPANF_00571 5.2e-113 3.4.17.14, 3.5.1.28 NU amidase activity
PIGPPANF_00572 1.5e-73 S Bacterial inner membrane protein
PIGPPANF_00573 1.3e-140 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
PIGPPANF_00574 2.3e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
PIGPPANF_00575 7.3e-53 glnB K Belongs to the P(II) protein family
PIGPPANF_00576 6.8e-226 amt P Ammonium Transporter
PIGPPANF_00577 3.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PIGPPANF_00578 1.2e-54 yabA L Involved in initiation control of chromosome replication
PIGPPANF_00579 7.5e-133 yaaT S stage 0 sporulation protein
PIGPPANF_00580 1.7e-159 holB 2.7.7.7 L dna polymerase iii
PIGPPANF_00581 5.9e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PIGPPANF_00583 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PIGPPANF_00584 3.2e-89 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PIGPPANF_00585 6e-91 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PIGPPANF_00586 2.5e-86 S Fusaric acid resistance protein-like
PIGPPANF_00587 8.5e-63 glnR K Transcriptional regulator
PIGPPANF_00588 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
PIGPPANF_00589 5.6e-115 pscB M CHAP domain protein
PIGPPANF_00590 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIGPPANF_00591 1.5e-33 ykzG S Belongs to the UPF0356 family
PIGPPANF_00592 8.4e-117 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
PIGPPANF_00593 2.6e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PIGPPANF_00594 1.3e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PIGPPANF_00595 3.9e-114 azlC E AzlC protein
PIGPPANF_00596 4.4e-47 azlD S branched-chain amino acid
PIGPPANF_00597 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PIGPPANF_00598 6.1e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PIGPPANF_00599 1.1e-153 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIGPPANF_00600 1.4e-26 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PIGPPANF_00601 1.8e-90 cvpA S toxin biosynthetic process
PIGPPANF_00602 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PIGPPANF_00603 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PIGPPANF_00605 1.7e-37
PIGPPANF_00606 1.3e-09
PIGPPANF_00608 3.2e-217 mutY L A G-specific adenine glycosylase
PIGPPANF_00609 7.2e-42 XK27_05745
PIGPPANF_00610 2.7e-46 rpsB J Belongs to the universal ribosomal protein uS2 family
PIGPPANF_00611 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PIGPPANF_00612 8.7e-81 S Putative small multi-drug export protein
PIGPPANF_00613 2e-74 ctsR K Belongs to the CtsR family
PIGPPANF_00614 0.0 clpC O Belongs to the ClpA ClpB family
PIGPPANF_00615 2.1e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PIGPPANF_00616 2.1e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PIGPPANF_00617 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PIGPPANF_00618 4.7e-140 S SseB protein N-terminal domain
PIGPPANF_00619 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
PIGPPANF_00621 3.1e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PIGPPANF_00622 3.6e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PIGPPANF_00624 1.1e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIGPPANF_00625 2.7e-91 yacP S RNA-binding protein containing a PIN domain
PIGPPANF_00626 1.1e-150 degV S DegV family
PIGPPANF_00628 5.1e-22 K Transcriptional
PIGPPANF_00629 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PIGPPANF_00630 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
PIGPPANF_00631 3e-194 int L Belongs to the 'phage' integrase family
PIGPPANF_00632 1.2e-42 S Helix-turn-helix domain
PIGPPANF_00633 8.2e-29 S Protein conserved in bacteria
PIGPPANF_00634 6.7e-89 H Methyltransferase
PIGPPANF_00635 4.6e-94 L Transposase
PIGPPANF_00636 5.7e-129 mccF V LD-carboxypeptidase
PIGPPANF_00637 6.6e-298 O MreB/Mbl protein
PIGPPANF_00639 5.8e-146 V Psort location CytoplasmicMembrane, score
PIGPPANF_00642 2.6e-13
PIGPPANF_00643 6.5e-227 dcuS 2.7.13.3 T protein histidine kinase activity
PIGPPANF_00644 1.1e-232 2.7.13.3 T protein histidine kinase activity
PIGPPANF_00645 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
PIGPPANF_00646 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PIGPPANF_00647 4.7e-126 S Protein of unknown function (DUF554)
PIGPPANF_00648 8.1e-134 ecsA_2 V abc transporter atp-binding protein
PIGPPANF_00649 1e-282 XK27_00765
PIGPPANF_00650 3.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PIGPPANF_00651 2.5e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PIGPPANF_00652 2.8e-64 yhaI J Membrane
PIGPPANF_00653 3.6e-208 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PIGPPANF_00654 2.8e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PIGPPANF_00656 7e-303 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIGPPANF_00657 1.4e-84 ytsP 1.8.4.14 T GAF domain-containing protein
PIGPPANF_00658 1.3e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PIGPPANF_00659 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
PIGPPANF_00662 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PIGPPANF_00663 1e-213 XK27_05110 P Chloride transporter ClC family
PIGPPANF_00664 1.9e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
PIGPPANF_00665 2.8e-277 clcA P Chloride transporter, ClC family
PIGPPANF_00666 1e-75 fld C Flavodoxin
PIGPPANF_00667 1.4e-17 XK27_08880
PIGPPANF_00668 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
PIGPPANF_00669 9.5e-149 estA CE1 S Esterase
PIGPPANF_00670 6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIGPPANF_00671 8.9e-136 XK27_08845 S abc transporter atp-binding protein
PIGPPANF_00672 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
PIGPPANF_00673 3.1e-176 XK27_08835 S ABC transporter substrate binding protein
PIGPPANF_00674 3.8e-18 S Domain of unknown function (DUF4649)
PIGPPANF_00675 9.5e-192 Q the current gene model (or a revised gene model) may contain a frame shift
PIGPPANF_00676 2.5e-81 lytC 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PIGPPANF_00677 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PIGPPANF_00678 6.4e-146 ycdO P periplasmic lipoprotein involved in iron transport
PIGPPANF_00679 5.8e-230 ycdB P peroxidase
PIGPPANF_00680 1.7e-291 ywbL P COG0672 High-affinity Fe2 Pb2 permease
PIGPPANF_00681 1.4e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PIGPPANF_00682 1.9e-23 tatA U protein secretion
PIGPPANF_00683 1.8e-212 msmX P Belongs to the ABC transporter superfamily
PIGPPANF_00684 3.7e-151 malG P ABC transporter (Permease
PIGPPANF_00685 2.2e-249 malF P ABC transporter (Permease
PIGPPANF_00686 4.3e-228 malX G ABC transporter
PIGPPANF_00687 1.6e-172 malR K Transcriptional regulator
PIGPPANF_00688 4.7e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
PIGPPANF_00689 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PIGPPANF_00690 2.6e-38
PIGPPANF_00691 6.1e-185 lplA 6.3.1.20 H Lipoate-protein ligase
PIGPPANF_00692 1.1e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
PIGPPANF_00693 0.0 pepN 3.4.11.2 E aminopeptidase
PIGPPANF_00694 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
PIGPPANF_00695 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIGPPANF_00696 1.5e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIGPPANF_00697 9.1e-156 pstA P phosphate transport system permease
PIGPPANF_00698 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
PIGPPANF_00699 2.6e-155 pstS P phosphate
PIGPPANF_00700 2.4e-245 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PIGPPANF_00701 7.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PIGPPANF_00702 4.3e-43 yktA S Belongs to the UPF0223 family
PIGPPANF_00703 4e-44 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PIGPPANF_00704 3.3e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PIGPPANF_00705 1.5e-147 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PIGPPANF_00706 2.1e-236 XK27_04775 S hemerythrin HHE cation binding domain
PIGPPANF_00707 8e-35 M1-755 P Hemerythrin HHE cation binding domain protein
PIGPPANF_00708 4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
PIGPPANF_00709 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PIGPPANF_00710 3.3e-138 S haloacid dehalogenase-like hydrolase
PIGPPANF_00711 6.6e-240 metY 2.5.1.49 E o-acetylhomoserine
PIGPPANF_00712 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PIGPPANF_00713 5.3e-240 agcS E (Alanine) symporter
PIGPPANF_00714 7.5e-242 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PIGPPANF_00715 4.9e-171 bglC K Transcriptional regulator
PIGPPANF_00716 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
PIGPPANF_00717 9.3e-81 yecS P ABC transporter (Permease
PIGPPANF_00718 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
PIGPPANF_00719 2.5e-235 nylA 3.5.1.4 J Belongs to the amidase family
PIGPPANF_00720 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PIGPPANF_00721 1e-122 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PIGPPANF_00722 1.5e-126 csm6 S Psort location Cytoplasmic, score
PIGPPANF_00723 6.4e-109 csm6 S Psort location Cytoplasmic, score
PIGPPANF_00724 1.7e-201 csm5 L CRISPR-associated RAMP protein, Csm5 family
PIGPPANF_00725 1.5e-161 csm4 L CRISPR-associated RAMP protein, Csm4 family
PIGPPANF_00726 3.2e-113 csm3 L RAMP superfamily
PIGPPANF_00727 2.2e-58 csm2 L Pfam:DUF310
PIGPPANF_00728 0.0 csm1 S CRISPR-associated protein Csm1 family
PIGPPANF_00729 6.6e-128 cas6 S Pfam:DUF2276
PIGPPANF_00731 5.4e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PIGPPANF_00732 3.5e-67 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PIGPPANF_00733 3.2e-75 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PIGPPANF_00734 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PIGPPANF_00735 1.6e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PIGPPANF_00736 1.4e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
PIGPPANF_00737 9.8e-133 S TraX protein
PIGPPANF_00738 1.2e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PIGPPANF_00739 0.0 ypuA S secreted protein
PIGPPANF_00740 9.6e-282 yhaI L Membrane
PIGPPANF_00744 4.2e-172 mutR K Helix-turn-helix XRE-family like proteins
PIGPPANF_00745 5.6e-278 S Psort location CytoplasmicMembrane, score
PIGPPANF_00746 5.3e-232 dinF V Mate efflux family protein
PIGPPANF_00747 6.6e-176 yclQ P ABC-type enterochelin transport system, periplasmic component
PIGPPANF_00748 0.0 V Type III restriction enzyme, res subunit
PIGPPANF_00749 7.1e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
PIGPPANF_00750 1.2e-140 2.4.2.3 F Phosphorylase superfamily
PIGPPANF_00751 1.5e-109 K Bacterial regulatory proteins, tetR family
PIGPPANF_00752 5.1e-177 ybhR V ABC-2 family transporter protein
PIGPPANF_00753 1.6e-126 ybhF_2 V abc transporter atp-binding protein
PIGPPANF_00756 1.2e-39 S Alpha/beta hydrolase of unknown function (DUF915)
PIGPPANF_00757 5.3e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIGPPANF_00758 9.8e-86 pat 2.3.1.183 M acetyltransferase
PIGPPANF_00759 9.6e-264 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIGPPANF_00760 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PIGPPANF_00761 4.2e-124 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
PIGPPANF_00762 1.4e-119 sdaAB 4.3.1.17 E L-serine dehydratase
PIGPPANF_00763 2e-147 sdaAA 4.3.1.17 E L-serine dehydratase
PIGPPANF_00764 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
PIGPPANF_00765 1e-162 yjlA EG membrane
PIGPPANF_00766 1.8e-79 3.4.21.89 S RDD family
PIGPPANF_00767 2.2e-48
PIGPPANF_00768 1.3e-85
PIGPPANF_00769 1.7e-21
PIGPPANF_00771 2.1e-140 S ABC-2 family transporter protein
PIGPPANF_00772 4.5e-59 S ABC-2 family transporter protein
PIGPPANF_00773 0.0 3.5.1.28 NU amidase activity
PIGPPANF_00774 2.4e-311 lpdA 1.8.1.4 C Dehydrogenase
PIGPPANF_00775 6e-207 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PIGPPANF_00776 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PIGPPANF_00777 1.5e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PIGPPANF_00778 5.7e-204 hpk9 2.7.13.3 T protein histidine kinase activity
PIGPPANF_00779 1.2e-225 2.7.13.3 T protein histidine kinase activity
PIGPPANF_00780 2.1e-306 S the current gene model (or a revised gene model) may contain a frame shift
PIGPPANF_00781 2e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PIGPPANF_00782 4.1e-121 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PIGPPANF_00783 8.4e-213 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PIGPPANF_00784 2e-247 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PIGPPANF_00785 4.5e-152 rssA S Phospholipase, patatin family
PIGPPANF_00786 6.5e-100 estA E Lysophospholipase L1 and related esterases
PIGPPANF_00787 5.2e-279 S unusual protein kinase
PIGPPANF_00788 4.1e-38 S granule-associated protein
PIGPPANF_00789 5.4e-283 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PIGPPANF_00790 1.2e-195 S hmm pf01594
PIGPPANF_00791 6.9e-107 G Belongs to the phosphoglycerate mutase family
PIGPPANF_00792 1.7e-108 G Belongs to the phosphoglycerate mutase family
PIGPPANF_00793 4.8e-108 pgm G Belongs to the phosphoglycerate mutase family
PIGPPANF_00794 3.7e-94 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PIGPPANF_00795 2.4e-30 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PIGPPANF_00797 1.1e-179 wbbI M transferase activity, transferring glycosyl groups
PIGPPANF_00798 3.4e-183 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
PIGPPANF_00799 8.2e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
PIGPPANF_00800 2.2e-244 epsU S Polysaccharide biosynthesis protein
PIGPPANF_00801 1e-130 cps3F
PIGPPANF_00802 4.9e-156 M Glycosyltransferase like family 2
PIGPPANF_00803 2.9e-147
PIGPPANF_00804 4.3e-22 Z012_10770 M Domain of unknown function (DUF1919)
PIGPPANF_00805 4.1e-209 wcoF M Glycosyltransferase, group 1 family protein
PIGPPANF_00806 3.4e-219 rgpAc GT4 M group 1 family protein
PIGPPANF_00807 8e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PIGPPANF_00808 1.2e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
PIGPPANF_00809 1.2e-110 cps4C M biosynthesis protein
PIGPPANF_00810 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
PIGPPANF_00811 1.5e-248 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
PIGPPANF_00812 6.4e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
PIGPPANF_00813 1.3e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
PIGPPANF_00814 2.4e-162 clcA_2 P chloride
PIGPPANF_00815 2.4e-50 S LemA family
PIGPPANF_00816 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PIGPPANF_00817 2e-84 S Protein of unknown function (DUF1697)
PIGPPANF_00818 2.7e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PIGPPANF_00819 9.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PIGPPANF_00820 2.4e-251 V Glucan-binding protein C
PIGPPANF_00821 3.6e-225 V Glucan-binding protein C
PIGPPANF_00822 2e-106 ung2 3.2.2.27 L Uracil-DNA glycosylase
PIGPPANF_00823 1.3e-270 pepV 3.5.1.18 E Dipeptidase
PIGPPANF_00824 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PIGPPANF_00825 2.5e-89 yybC
PIGPPANF_00826 1.6e-74 XK27_03610 K Gnat family
PIGPPANF_00827 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PIGPPANF_00828 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PIGPPANF_00829 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PIGPPANF_00830 5.6e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PIGPPANF_00831 5.5e-17 M LysM domain
PIGPPANF_00832 9.6e-86 ebsA S Family of unknown function (DUF5322)
PIGPPANF_00833 8.5e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PIGPPANF_00834 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PIGPPANF_00835 1.6e-94 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PIGPPANF_00836 4.5e-222 G COG0457 FOG TPR repeat
PIGPPANF_00837 4e-175 yubA S permease
PIGPPANF_00838 7.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
PIGPPANF_00839 1.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PIGPPANF_00840 3.2e-124 ftsE D cell division ATP-binding protein FtsE
PIGPPANF_00841 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PIGPPANF_00842 3.5e-205 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PIGPPANF_00843 4.4e-152 yjjH S Calcineurin-like phosphoesterase
PIGPPANF_00844 8e-129 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PIGPPANF_00845 0.0 pacL 3.6.3.8 P cation transport ATPase
PIGPPANF_00846 6.5e-66 ywiB S Domain of unknown function (DUF1934)
PIGPPANF_00847 6.5e-143 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
PIGPPANF_00848 7.8e-146 yidA S hydrolases of the HAD superfamily
PIGPPANF_00849 1.9e-225 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
PIGPPANF_00850 1.5e-56 S Protein of unknown function (DUF454)
PIGPPANF_00851 2.7e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
PIGPPANF_00852 6.2e-233 vicK 2.7.13.3 T Histidine kinase
PIGPPANF_00853 6.4e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIGPPANF_00854 6e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PIGPPANF_00855 3.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PIGPPANF_00856 0.0 dnaE 2.7.7.7 L DNA polymerase
PIGPPANF_00857 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PIGPPANF_00858 4.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PIGPPANF_00859 2.5e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PIGPPANF_00860 4.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PIGPPANF_00861 1.5e-36 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIGPPANF_00862 2e-70 S SnoaL-like polyketide cyclase
PIGPPANF_00863 1.2e-52 hxlR K HxlR-like helix-turn-helix
PIGPPANF_00864 6e-217 ftsW D Belongs to the SEDS family
PIGPPANF_00865 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PIGPPANF_00866 6.7e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PIGPPANF_00867 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PIGPPANF_00868 6.5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PIGPPANF_00869 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIGPPANF_00870 5.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PIGPPANF_00871 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
PIGPPANF_00872 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIGPPANF_00873 4.6e-20 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
PIGPPANF_00875 1.2e-75 desK 2.7.13.3 T Histidine kinase
PIGPPANF_00876 9.5e-35 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIGPPANF_00877 0.0 S AAA ATPase domain
PIGPPANF_00878 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PIGPPANF_00879 5.5e-136 S Phenazine biosynthesis protein
PIGPPANF_00880 2.3e-255 proWX P ABC transporter
PIGPPANF_00881 9.9e-124 proV E abc transporter atp-binding protein
PIGPPANF_00882 8.1e-150 C alcohol dehydrogenase
PIGPPANF_00883 8.4e-65 mgrA K Transcriptional regulator, MarR family
PIGPPANF_00884 3.1e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PIGPPANF_00885 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PIGPPANF_00888 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PIGPPANF_00890 8.2e-137 IQ Acetoin reductase
PIGPPANF_00891 3.1e-44 pspE P Rhodanese-like protein
PIGPPANF_00892 8.8e-72 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PIGPPANF_00893 3.5e-224 XK27_05470 E Methionine synthase
PIGPPANF_00894 1.9e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PIGPPANF_00895 3.9e-230 T PhoQ Sensor
PIGPPANF_00896 2.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIGPPANF_00897 5.5e-147 S TraX protein
PIGPPANF_00899 5.9e-52 V ABC-2 family transporter protein
PIGPPANF_00900 4.9e-85 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
PIGPPANF_00901 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PIGPPANF_00902 1.7e-156 dprA LU DNA protecting protein DprA
PIGPPANF_00903 1.9e-164 GK ROK family
PIGPPANF_00904 4.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIGPPANF_00905 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PIGPPANF_00906 1.6e-128 K DNA-binding helix-turn-helix protein
PIGPPANF_00907 4.6e-91 niaR S small molecule binding protein (contains 3H domain)
PIGPPANF_00908 5.3e-87
PIGPPANF_00909 3.8e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PIGPPANF_00910 3.9e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PIGPPANF_00911 2.2e-125 gntR1 K transcriptional
PIGPPANF_00912 6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PIGPPANF_00913 7.9e-188 adhP 1.1.1.1 C alcohol dehydrogenase
PIGPPANF_00914 1.3e-44
PIGPPANF_00915 2.9e-50
PIGPPANF_00916 1.2e-266 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIGPPANF_00917 1.9e-155 aatB ET ABC transporter substrate-binding protein
PIGPPANF_00918 9.8e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
PIGPPANF_00919 1.4e-105 artQ P ABC transporter (Permease
PIGPPANF_00920 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
PIGPPANF_00921 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PIGPPANF_00922 7.6e-166 cpsY K Transcriptional regulator
PIGPPANF_00923 1.3e-123 mur1 3.4.17.14, 3.5.1.28 NU muramidase
PIGPPANF_00924 7.6e-167 yeiH S Membrane
PIGPPANF_00926 2.6e-09
PIGPPANF_00927 4.9e-282 adcA P Belongs to the bacterial solute-binding protein 9 family
PIGPPANF_00928 1.5e-141 XK27_10720 D peptidase activity
PIGPPANF_00929 4e-275 pepD E Dipeptidase
PIGPPANF_00930 8.2e-160 whiA K May be required for sporulation
PIGPPANF_00931 1.8e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PIGPPANF_00932 5.5e-161 rapZ S Displays ATPase and GTPase activities
PIGPPANF_00933 2.9e-134 yejC S cyclic nucleotide-binding protein
PIGPPANF_00934 6.7e-202 D nuclear chromosome segregation
PIGPPANF_00935 7.2e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
PIGPPANF_00936 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PIGPPANF_00937 8.8e-83 queD 4.1.2.50, 4.2.3.12 H synthase
PIGPPANF_00938 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PIGPPANF_00939 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
PIGPPANF_00940 3.7e-19
PIGPPANF_00941 1.9e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PIGPPANF_00942 2.8e-213 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PIGPPANF_00943 1.1e-81 ypmB S Protein conserved in bacteria
PIGPPANF_00944 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PIGPPANF_00945 5.2e-113 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PIGPPANF_00946 8.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
PIGPPANF_00947 2.3e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
PIGPPANF_00948 1.7e-279 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PIGPPANF_00949 3.1e-190 tcsA S membrane
PIGPPANF_00950 7.4e-65 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PIGPPANF_00951 7.9e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PIGPPANF_00952 2.3e-229 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PIGPPANF_00953 7.8e-103 rsmC 2.1.1.172 J Methyltransferase small domain protein
PIGPPANF_00954 4.4e-169 coaA 2.7.1.33 F Pantothenic acid kinase
PIGPPANF_00955 2.3e-29 rpsT J Binds directly to 16S ribosomal RNA
PIGPPANF_00956 9.8e-237 T PhoQ Sensor
PIGPPANF_00957 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIGPPANF_00958 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PIGPPANF_00959 6.9e-111 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
PIGPPANF_00960 4.8e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PIGPPANF_00961 1.5e-90 panT S ECF transporter, substrate-specific component
PIGPPANF_00962 2.8e-131 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
PIGPPANF_00963 2.3e-75 S Protein of unknown function (DUF1524)
PIGPPANF_00964 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PIGPPANF_00966 2.9e-134 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PIGPPANF_00967 1.6e-192 MA20_36090 S Protein of unknown function (DUF2974)
PIGPPANF_00968 1.8e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIGPPANF_00969 1.2e-154 5.2.1.8 G hydrolase
PIGPPANF_00970 7.8e-27 P Hemerythrin HHE cation binding domain protein
PIGPPANF_00971 9.4e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
PIGPPANF_00972 3.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PIGPPANF_00973 9.6e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
PIGPPANF_00975 2e-174 S hydrolase
PIGPPANF_00976 8.4e-23
PIGPPANF_00977 5e-142 M LysM domain
PIGPPANF_00978 2.6e-131 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
PIGPPANF_00979 3.6e-140 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PIGPPANF_00980 4.4e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
PIGPPANF_00981 4.5e-183 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PIGPPANF_00982 7.8e-219 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PIGPPANF_00983 1.6e-121 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PIGPPANF_00984 1.4e-204 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PIGPPANF_00985 7.2e-129 yxkH G deacetylase
PIGPPANF_00986 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PIGPPANF_00987 5.9e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PIGPPANF_00988 3.7e-149 rarD S Transporter
PIGPPANF_00989 5.2e-17 T peptidase
PIGPPANF_00990 2.3e-14 coiA 3.6.4.12 S Competence protein
PIGPPANF_00991 1.7e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PIGPPANF_00992 3.7e-94 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PIGPPANF_00993 6.6e-09
PIGPPANF_00996 3.5e-228 2.7.13.3 T GHKL domain
PIGPPANF_00997 9e-133 agrA KT phosphorelay signal transduction system
PIGPPANF_00998 4e-07
PIGPPANF_00999 2.9e-134 agrA KT response regulator
PIGPPANF_01000 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PIGPPANF_01003 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PIGPPANF_01004 3.5e-85 yxjI S LURP-one-related
PIGPPANF_01005 2.1e-165 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
PIGPPANF_01006 3e-119 yrrM 2.1.1.104 S O-Methyltransferase
PIGPPANF_01007 1.2e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
PIGPPANF_01008 0.0 pepF E oligoendopeptidase F
PIGPPANF_01009 1.9e-162 coiA 3.6.4.12 S Competence protein
PIGPPANF_01010 2.1e-258 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PIGPPANF_01011 4.4e-111 S CAAX amino terminal protease family protein
PIGPPANF_01012 4.7e-168 K transcriptional regulator (lysR family)
PIGPPANF_01013 5.8e-160 S reductase
PIGPPANF_01014 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PIGPPANF_01019 2.4e-187 phoH T phosphate starvation-inducible protein PhoH
PIGPPANF_01020 1.4e-128 sip M LysM domain protein
PIGPPANF_01021 3.7e-34 yozE S Belongs to the UPF0346 family
PIGPPANF_01022 1.3e-159 cvfB S Protein conserved in bacteria
PIGPPANF_01023 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PIGPPANF_01024 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PIGPPANF_01025 8.8e-210 sptS 2.7.13.3 T Histidine kinase
PIGPPANF_01026 1.7e-114 T response regulator
PIGPPANF_01027 1.5e-109 2.7.6.5 S Region found in RelA / SpoT proteins
PIGPPANF_01028 9.1e-110 K Acetyltransferase (GNAT) family
PIGPPANF_01029 0.0 lmrA2 V abc transporter atp-binding protein
PIGPPANF_01030 2.5e-309 lmrA1 V abc transporter atp-binding protein
PIGPPANF_01031 2.3e-75 K DNA-binding transcription factor activity
PIGPPANF_01032 1.9e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PIGPPANF_01033 6.9e-266 S Psort location CytoplasmicMembrane, score
PIGPPANF_01034 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PIGPPANF_01035 1e-209 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
PIGPPANF_01036 3.7e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
PIGPPANF_01037 1.7e-26 U response to pH
PIGPPANF_01038 0.0 yfmR S abc transporter atp-binding protein
PIGPPANF_01039 8.7e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PIGPPANF_01040 1.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PIGPPANF_01041 1.8e-145 XK27_08360 S EDD domain protein, DegV family
PIGPPANF_01042 5e-63 WQ51_03320 S cog cog4835
PIGPPANF_01043 4.7e-131 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PIGPPANF_01044 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PIGPPANF_01045 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PIGPPANF_01046 1.4e-82 2.3.1.128 K acetyltransferase
PIGPPANF_01047 1.7e-254 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PIGPPANF_01048 1.4e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PIGPPANF_01049 4.8e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PIGPPANF_01050 1.1e-209 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
PIGPPANF_01052 6.5e-224 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PIGPPANF_01053 3.1e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PIGPPANF_01054 0.0 fruA 2.7.1.202 G phosphotransferase system
PIGPPANF_01055 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PIGPPANF_01056 2.3e-112 fruR K transcriptional
PIGPPANF_01057 1.2e-206 rny D Endoribonuclease that initiates mRNA decay
PIGPPANF_01058 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PIGPPANF_01059 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PIGPPANF_01060 1e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PIGPPANF_01061 1.8e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PIGPPANF_01062 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PIGPPANF_01063 1.5e-51 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PIGPPANF_01064 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PIGPPANF_01065 6.2e-126 IQ reductase
PIGPPANF_01066 4.7e-163 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PIGPPANF_01067 1.5e-298 V abc transporter atp-binding protein
PIGPPANF_01068 0.0 V abc transporter atp-binding protein
PIGPPANF_01069 3.8e-186 XK27_10075 S abc transporter atp-binding protein
PIGPPANF_01070 4.4e-11
PIGPPANF_01073 1.6e-49 bta 1.8.1.8 CO cell redox homeostasis
PIGPPANF_01074 1.4e-58 L thioesterase
PIGPPANF_01075 3.3e-141 S Macro domain protein
PIGPPANF_01076 2.4e-50 trxA O Belongs to the thioredoxin family
PIGPPANF_01077 4.9e-70 yccU S CoA-binding protein
PIGPPANF_01078 1.5e-141 tatD L Hydrolase, tatd
PIGPPANF_01079 1.8e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PIGPPANF_01080 2.4e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PIGPPANF_01082 3.5e-160 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PIGPPANF_01083 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PIGPPANF_01084 1.2e-112 thiN 2.7.6.2 H thiamine pyrophosphokinase
PIGPPANF_01085 2.1e-166 rmuC S RmuC domain protein
PIGPPANF_01086 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
PIGPPANF_01087 6.9e-142 purR 2.4.2.7 F operon repressor
PIGPPANF_01088 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PIGPPANF_01089 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PIGPPANF_01090 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PIGPPANF_01094 3.8e-11
PIGPPANF_01095 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PIGPPANF_01096 0.0 3.5.1.28 M domain protein
PIGPPANF_01097 0.0 S dextransucrase activity
PIGPPANF_01098 4.7e-88 M Putative cell wall binding repeat
PIGPPANF_01099 0.0 S dextransucrase activity
PIGPPANF_01100 1.9e-101 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PIGPPANF_01101 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PIGPPANF_01102 4.9e-295 S dextransucrase activity
PIGPPANF_01103 2.1e-70 yhgF K Transcriptional accessory protein
PIGPPANF_01104 2.2e-41 pspC KT PspC domain
PIGPPANF_01105 4.1e-167 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PIGPPANF_01106 4.9e-145 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PIGPPANF_01107 3.1e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PIGPPANF_01108 9.7e-66 ytxH S General stress protein
PIGPPANF_01110 8.9e-178 yegQ O Peptidase U32
PIGPPANF_01111 7.5e-252 yegQ O Peptidase U32
PIGPPANF_01112 1.3e-85 bioY S biotin synthase
PIGPPANF_01114 1.1e-33 XK27_12190 S protein conserved in bacteria
PIGPPANF_01115 6.2e-233 mntH P H( )-stimulated, divalent metal cation uptake system
PIGPPANF_01117 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PIGPPANF_01118 6e-303 dnaK O Heat shock 70 kDa protein
PIGPPANF_01119 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PIGPPANF_01120 4.9e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PIGPPANF_01121 5.5e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
PIGPPANF_01122 8.2e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PIGPPANF_01123 8.6e-133 ais G Phosphoglycerate mutase
PIGPPANF_01124 2.8e-241 XK27_08635 S UPF0210 protein
PIGPPANF_01125 2.3e-38 gcvR T UPF0237 protein
PIGPPANF_01126 3.7e-232 capA M Bacterial capsule synthesis protein
PIGPPANF_01127 8.6e-148 srtB 3.4.22.70 S Sortase family
PIGPPANF_01129 4.5e-29 K Helix-turn-helix domain
PIGPPANF_01130 1.1e-19
PIGPPANF_01132 1.9e-86 sigH K DNA-templated transcription, initiation
PIGPPANF_01133 5.8e-138 ykuT M mechanosensitive ion channel
PIGPPANF_01134 7.6e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PIGPPANF_01135 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PIGPPANF_01136 3.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PIGPPANF_01137 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
PIGPPANF_01138 2.1e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
PIGPPANF_01139 4.2e-175 prmA J Ribosomal protein L11 methyltransferase
PIGPPANF_01140 3.8e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PIGPPANF_01141 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PIGPPANF_01142 9.1e-83 nrdI F Belongs to the NrdI family
PIGPPANF_01143 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PIGPPANF_01144 1.3e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PIGPPANF_01145 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PIGPPANF_01146 1.9e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PIGPPANF_01147 1.9e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PIGPPANF_01148 1.8e-105 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PIGPPANF_01149 8.2e-181 yhjX P Major Facilitator
PIGPPANF_01150 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PIGPPANF_01151 1.3e-81 V VanZ like family
PIGPPANF_01152 6.2e-181 D nuclear chromosome segregation
PIGPPANF_01153 2.2e-123 glnQ E abc transporter atp-binding protein
PIGPPANF_01154 1.3e-271 glnP P ABC transporter
PIGPPANF_01155 4.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PIGPPANF_01156 2.4e-17 S Protein of unknown function (DUF3021)
PIGPPANF_01157 5.9e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PIGPPANF_01158 1.9e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
PIGPPANF_01159 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PIGPPANF_01160 5.9e-233 sufD O assembly protein SufD
PIGPPANF_01161 3.4e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PIGPPANF_01162 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
PIGPPANF_01163 3.2e-272 sufB O assembly protein SufB
PIGPPANF_01164 5.5e-27
PIGPPANF_01165 1.2e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PIGPPANF_01166 1.8e-181 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PIGPPANF_01167 5e-70 adcR K transcriptional
PIGPPANF_01168 7.1e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
PIGPPANF_01169 5.6e-128 adcB P ABC transporter (Permease
PIGPPANF_01170 5.5e-159 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PIGPPANF_01171 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PIGPPANF_01172 7.6e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
PIGPPANF_01173 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
PIGPPANF_01174 1e-125 yeeN K transcriptional regulatory protein
PIGPPANF_01175 5.9e-47 yajC U protein transport
PIGPPANF_01176 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PIGPPANF_01177 4.6e-143 cdsA 2.7.7.41 S Belongs to the CDS family
PIGPPANF_01178 6.7e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PIGPPANF_01179 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PIGPPANF_01180 0.0 WQ51_06230 S ABC transporter
PIGPPANF_01181 1.4e-142 cmpC S abc transporter atp-binding protein
PIGPPANF_01182 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PIGPPANF_01183 3.4e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PIGPPANF_01185 1.5e-44
PIGPPANF_01186 7.6e-55 S TM2 domain
PIGPPANF_01187 3.5e-160 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PIGPPANF_01188 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PIGPPANF_01189 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
PIGPPANF_01190 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
PIGPPANF_01191 6.8e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
PIGPPANF_01192 3.6e-143 cof S Sucrose-6F-phosphate phosphohydrolase
PIGPPANF_01193 3.6e-132 glcR K transcriptional regulator (DeoR family)
PIGPPANF_01194 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PIGPPANF_01195 4.2e-72 K transcriptional
PIGPPANF_01196 5.7e-225 S COG1073 Hydrolases of the alpha beta superfamily
PIGPPANF_01197 7.7e-114 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PIGPPANF_01198 3e-120 yaaA S Belongs to the UPF0246 family
PIGPPANF_01199 9.3e-167 XK27_01785 S cog cog1284
PIGPPANF_01200 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PIGPPANF_01202 1.8e-237 hisS 6.1.1.21 J histidyl-tRNA synthetase
PIGPPANF_01203 8e-73 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PIGPPANF_01204 8.9e-51 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PIGPPANF_01205 2.9e-10 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PIGPPANF_01206 3.6e-218 metE 2.1.1.14 E Methionine synthase
PIGPPANF_01207 3.4e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PIGPPANF_01208 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PIGPPANF_01209 2.3e-130
PIGPPANF_01211 1.3e-77 S EcsC protein family
PIGPPANF_01212 0.0 S Protein of unknown function DUF262
PIGPPANF_01216 3.8e-113 nudL L hydrolase
PIGPPANF_01217 8.5e-51 K transcriptional regulator, PadR family
PIGPPANF_01218 1.6e-60 XK27_06920 S Protein of unknown function (DUF1700)
PIGPPANF_01219 7e-105 S Putative adhesin
PIGPPANF_01220 1.8e-158 XK27_06930 V domain protein
PIGPPANF_01221 7.9e-94 XK27_06935 K transcriptional regulator
PIGPPANF_01222 2.2e-52 ypaA M Membrane
PIGPPANF_01223 1.1e-10
PIGPPANF_01224 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PIGPPANF_01225 1.8e-47 veg S Biofilm formation stimulator VEG
PIGPPANF_01226 6.5e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PIGPPANF_01227 2.2e-73 rplI J binds to the 23S rRNA
PIGPPANF_01228 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PIGPPANF_01229 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PIGPPANF_01230 1e-97 yvbG U UPF0056 membrane protein
PIGPPANF_01231 4.7e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PIGPPANF_01232 6e-305 S Bacterial membrane protein, YfhO
PIGPPANF_01233 1.5e-65 isaA GH23 M Immunodominant staphylococcal antigen A
PIGPPANF_01234 2.5e-61 lytE M LysM domain protein
PIGPPANF_01235 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIGPPANF_01236 5.4e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIGPPANF_01237 2.7e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIGPPANF_01238 2e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PIGPPANF_01239 1.7e-127 S sequence-specific DNA binding
PIGPPANF_01240 1.4e-234 ymfH S Peptidase M16
PIGPPANF_01241 6.7e-229 ymfF S Peptidase M16
PIGPPANF_01242 4.9e-58 yaaA S S4 domain protein YaaA
PIGPPANF_01243 5.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PIGPPANF_01244 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PIGPPANF_01245 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PIGPPANF_01246 7.8e-152 yvjA S membrane
PIGPPANF_01247 1.1e-305 ybiT S abc transporter atp-binding protein
PIGPPANF_01248 0.0 XK27_10405 S Bacterial membrane protein YfhO
PIGPPANF_01252 2.4e-119 yoaK S Protein of unknown function (DUF1275)
PIGPPANF_01253 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PIGPPANF_01254 1e-205 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
PIGPPANF_01255 7.7e-135 parB K Belongs to the ParB family
PIGPPANF_01256 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PIGPPANF_01257 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PIGPPANF_01258 3.2e-29 yyzM S Protein conserved in bacteria
PIGPPANF_01259 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PIGPPANF_01260 1.5e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PIGPPANF_01261 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PIGPPANF_01262 6.3e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PIGPPANF_01263 3e-60 divIC D Septum formation initiator
PIGPPANF_01265 1.3e-232 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
PIGPPANF_01266 3.7e-227 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PIGPPANF_01267 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PIGPPANF_01268 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PIGPPANF_01269 7.5e-14
PIGPPANF_01270 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PIGPPANF_01271 2.2e-288 ccs S the current gene model (or a revised gene model) may contain a frame shift
PIGPPANF_01272 3.2e-44 yrzB S Belongs to the UPF0473 family
PIGPPANF_01273 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PIGPPANF_01274 6.3e-44 yrzL S Belongs to the UPF0297 family
PIGPPANF_01275 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PIGPPANF_01276 1.8e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
PIGPPANF_01278 1.5e-214 int L Belongs to the 'phage' integrase family
PIGPPANF_01279 1.9e-18 S Domain of unknown function (DUF3173)
PIGPPANF_01280 1.2e-156 L Replication initiation factor
PIGPPANF_01281 5.5e-89 K sequence-specific DNA binding
PIGPPANF_01282 6.2e-97 K WHG domain
PIGPPANF_01283 1.6e-171 ydhF S Aldo keto reductase
PIGPPANF_01284 1.4e-06 S Protein of unknown function (DUF3169)
PIGPPANF_01285 9.4e-27 XK27_07105 K transcriptional
PIGPPANF_01286 7.2e-31
PIGPPANF_01287 5.1e-110 XK27_02070 S nitroreductase
PIGPPANF_01288 2.9e-151 1.13.11.2 S glyoxalase
PIGPPANF_01289 1.5e-74 ywnA K Transcriptional regulator
PIGPPANF_01290 7e-153 E Alpha/beta hydrolase of unknown function (DUF915)
PIGPPANF_01291 1.1e-226 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIGPPANF_01292 3.7e-168 bcrA V abc transporter atp-binding protein
PIGPPANF_01293 2.4e-125 S ABC-2 family transporter protein
PIGPPANF_01294 5.9e-131 T PhoQ Sensor
PIGPPANF_01295 2.1e-123 T Xre family transcriptional regulator
PIGPPANF_01296 4.1e-110 drgA C nitroreductase
PIGPPANF_01297 2.5e-108 yoaK S Protein of unknown function (DUF1275)
PIGPPANF_01298 7.6e-39 DJ nuclease activity
PIGPPANF_01299 3.2e-30 XK27_10490
PIGPPANF_01300 2.7e-157 yvgN C reductase
PIGPPANF_01301 4.2e-209 S Tetratricopeptide repeat
PIGPPANF_01302 0.0 lacL 3.2.1.23 G -beta-galactosidase
PIGPPANF_01303 0.0 lacS G transporter
PIGPPANF_01304 5.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PIGPPANF_01305 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PIGPPANF_01306 2.2e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PIGPPANF_01307 2.5e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PIGPPANF_01308 1.4e-181 galR K Transcriptional regulator
PIGPPANF_01309 5.4e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
PIGPPANF_01310 2.2e-227 vncS 2.7.13.3 T Histidine kinase
PIGPPANF_01311 9.8e-115 K Response regulator receiver domain protein
PIGPPANF_01312 2.9e-233 vex3 V Efflux ABC transporter, permease protein
PIGPPANF_01313 1.3e-108 vex2 V abc transporter atp-binding protein
PIGPPANF_01314 6.2e-182 vex1 V Efflux ABC transporter, permease protein
PIGPPANF_01315 1.1e-283 XK27_07020 S Belongs to the UPF0371 family
PIGPPANF_01317 4.3e-200 gldA 1.1.1.6 C glycerol dehydrogenase
PIGPPANF_01318 3.1e-181 XK27_10475 S oxidoreductase
PIGPPANF_01319 2.2e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
PIGPPANF_01320 2.6e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
PIGPPANF_01321 1e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
PIGPPANF_01322 1.6e-225 thrE K Psort location CytoplasmicMembrane, score
PIGPPANF_01323 0.0 M Putative cell wall binding repeat
PIGPPANF_01324 4e-08 S Enterocin A Immunity
PIGPPANF_01325 2.8e-49 S ParE toxin of type II toxin-antitoxin system, parDE
PIGPPANF_01326 1.3e-45 L RelB antitoxin
PIGPPANF_01327 9e-08 K Acetyltransferase (GNAT) domain
PIGPPANF_01329 2.7e-13 S Protein of unknown function (DUF1648)
PIGPPANF_01330 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
PIGPPANF_01331 1.5e-111 yhfC S Putative membrane peptidase family (DUF2324)
PIGPPANF_01332 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PIGPPANF_01334 4e-252 S dextransucrase activity
PIGPPANF_01335 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PIGPPANF_01336 2.3e-13 M Putative cell wall binding repeat
PIGPPANF_01337 1.4e-65 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
PIGPPANF_01339 6.3e-282 S Protein of unknown function (DUF3114)
PIGPPANF_01340 1.8e-101 2.3.1.128 K Acetyltransferase GNAT Family
PIGPPANF_01341 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PIGPPANF_01342 7e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
PIGPPANF_01343 2.3e-180 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
PIGPPANF_01344 1.3e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PIGPPANF_01345 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PIGPPANF_01346 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PIGPPANF_01347 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PIGPPANF_01348 1.6e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PIGPPANF_01349 2.1e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PIGPPANF_01350 4.9e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PIGPPANF_01353 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIGPPANF_01354 9.7e-170 vraS 2.7.13.3 T Histidine kinase
PIGPPANF_01355 7.2e-116 yvqF S Membrane
PIGPPANF_01356 6.5e-94 kcsA P Ion transport protein
PIGPPANF_01357 7e-291 prkC 2.7.11.1 KLT serine threonine protein kinase
PIGPPANF_01358 1e-134 stp 3.1.3.16 T phosphatase
PIGPPANF_01359 1.1e-242 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PIGPPANF_01360 1.5e-169 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PIGPPANF_01361 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PIGPPANF_01362 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
PIGPPANF_01363 4.4e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PIGPPANF_01364 1.2e-194 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PIGPPANF_01365 4e-142 XK27_02985 S overlaps another CDS with the same product name
PIGPPANF_01366 3.8e-145 supH S overlaps another CDS with the same product name
PIGPPANF_01367 1.9e-62 yvoA_1 K Transcriptional
PIGPPANF_01368 5.4e-119 skfE V abc transporter atp-binding protein
PIGPPANF_01369 1.7e-129 V Psort location CytoplasmicMembrane, score
PIGPPANF_01370 3.1e-170 oppF P Belongs to the ABC transporter superfamily
PIGPPANF_01371 1.3e-201 oppD P Belongs to the ABC transporter superfamily
PIGPPANF_01372 3.5e-166 amiD P ABC transporter (Permease
PIGPPANF_01373 2.1e-277 amiC P ABC transporter (Permease
PIGPPANF_01374 8.2e-311 amiA E ABC transporter, substrate-binding protein, family 5
PIGPPANF_01375 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PIGPPANF_01376 2.6e-175 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PIGPPANF_01377 1e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PIGPPANF_01378 3.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PIGPPANF_01379 6.7e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
PIGPPANF_01380 5.4e-101 yjbK S Adenylate cyclase
PIGPPANF_01381 5.1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIGPPANF_01382 8.9e-209 iscS 2.8.1.7 E Cysteine desulfurase
PIGPPANF_01383 8.2e-60 XK27_04120 S Putative amino acid metabolism
PIGPPANF_01384 1.4e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PIGPPANF_01385 1.7e-128 puuD T peptidase C26
PIGPPANF_01386 2.6e-118 radC E Belongs to the UPF0758 family
PIGPPANF_01387 1.2e-278 rgpF M Rhamnan synthesis protein F
PIGPPANF_01388 2.4e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PIGPPANF_01389 6.8e-142 rgpC GM Transport permease protein
PIGPPANF_01390 1.6e-171 rgpB GT2 M Glycosyltransferase, group 2 family protein
PIGPPANF_01391 7e-225 rgpA GT4 M Domain of unknown function (DUF1972)
PIGPPANF_01392 2.4e-223 GT4 M transferase activity, transferring glycosyl groups
PIGPPANF_01393 3.6e-219 M Psort location CytoplasmicMembrane, score
PIGPPANF_01394 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
PIGPPANF_01395 1.2e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
PIGPPANF_01396 8.4e-44 S Uncharacterized conserved protein (DUF2304)
PIGPPANF_01397 7e-127 arnC M group 2 family protein
PIGPPANF_01398 6.4e-142 M Glycosyl transferase family 8
PIGPPANF_01399 1.1e-165 amrA S polysaccharide biosynthetic process
PIGPPANF_01400 7.3e-61 S Psort location CytoplasmicMembrane, score
PIGPPANF_01401 4.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PIGPPANF_01402 2.7e-217 S Predicted membrane protein (DUF2142)
PIGPPANF_01403 1.5e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PIGPPANF_01404 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
PIGPPANF_01405 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PIGPPANF_01406 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PIGPPANF_01407 9.9e-51 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PIGPPANF_01408 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PIGPPANF_01409 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
PIGPPANF_01410 4e-201 arcT 2.6.1.1 E Aminotransferase
PIGPPANF_01411 1.2e-135 ET Belongs to the bacterial solute-binding protein 3 family
PIGPPANF_01412 3.2e-139 ET ABC transporter
PIGPPANF_01413 1.2e-82 mutT 3.6.1.55 F Nudix family
PIGPPANF_01414 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PIGPPANF_01416 1.1e-164 S CAAX amino terminal protease family protein
PIGPPANF_01417 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
PIGPPANF_01418 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
PIGPPANF_01419 1.7e-17 XK27_00735
PIGPPANF_01420 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PIGPPANF_01422 1.5e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PIGPPANF_01423 9.8e-10 O ADP-ribosylglycohydrolase
PIGPPANF_01424 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
PIGPPANF_01425 3.9e-60 ycaO O OsmC-like protein
PIGPPANF_01427 9.8e-150 EG Permeases of the drug metabolite transporter (DMT) superfamily
PIGPPANF_01428 8.5e-08 N PFAM Uncharacterised protein family UPF0150
PIGPPANF_01429 6.5e-111 serB 3.1.3.3 E phosphoserine phosphatase
PIGPPANF_01430 2.9e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PIGPPANF_01431 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIGPPANF_01432 1.9e-95 3.1.3.18 S IA, variant 1
PIGPPANF_01433 9.4e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PIGPPANF_01434 5.9e-56 lrgA S Effector of murein hydrolase LrgA
PIGPPANF_01436 1.6e-58 arsC 1.20.4.1 P Belongs to the ArsC family
PIGPPANF_01437 5.9e-72 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
PIGPPANF_01438 5.3e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIGPPANF_01439 1.7e-104 wecD M Acetyltransferase (GNAT) domain
PIGPPANF_01440 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PIGPPANF_01441 2.6e-150 GK ROK family
PIGPPANF_01442 2e-70 gloA 4.4.1.5 E Lactoylglutathione lyase
PIGPPANF_01443 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
PIGPPANF_01444 2.4e-203 potD P spermidine putrescine ABC transporter
PIGPPANF_01445 1.5e-130 potC P ABC-type spermidine putrescine transport system, permease component II
PIGPPANF_01446 1.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
PIGPPANF_01447 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PIGPPANF_01448 5.8e-166 murB 1.3.1.98 M cell wall formation
PIGPPANF_01449 1.4e-76 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PIGPPANF_01450 5e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PIGPPANF_01451 3.1e-294 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
PIGPPANF_01452 4.2e-144 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PIGPPANF_01453 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
PIGPPANF_01454 0.0 ydaO E amino acid
PIGPPANF_01455 3.1e-234 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PIGPPANF_01456 1.5e-36 ylqC L Belongs to the UPF0109 family
PIGPPANF_01457 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PIGPPANF_01459 1.7e-211 2.7.13.3 T protein histidine kinase activity
PIGPPANF_01460 4.2e-122 agrA KT phosphorelay signal transduction system
PIGPPANF_01461 7.4e-162 O protein import
PIGPPANF_01462 6.2e-165 tehB 2.1.1.265 PQ tellurite resistance protein tehb
PIGPPANF_01463 2.9e-17 yjdB S Domain of unknown function (DUF4767)
PIGPPANF_01464 1.5e-61 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PIGPPANF_01466 9.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
PIGPPANF_01467 3.7e-71 S QueT transporter
PIGPPANF_01469 3.2e-170 yfjR K regulation of single-species biofilm formation
PIGPPANF_01471 4.8e-185 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PIGPPANF_01472 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PIGPPANF_01473 4.8e-85 ccl S cog cog4708
PIGPPANF_01474 6.5e-160 rbn E Belongs to the UPF0761 family
PIGPPANF_01475 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
PIGPPANF_01476 3e-232 ytoI K transcriptional regulator containing CBS domains
PIGPPANF_01477 3.1e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
PIGPPANF_01478 2.1e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIGPPANF_01479 0.0 comEC S Competence protein ComEC
PIGPPANF_01480 5.8e-89 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PIGPPANF_01481 2.4e-141 plsC 2.3.1.51 I Acyltransferase
PIGPPANF_01482 4.6e-142 nodB3 G deacetylase
PIGPPANF_01483 7.9e-140 yabB 2.1.1.223 L Methyltransferase
PIGPPANF_01484 3e-41 yazA L endonuclease containing a URI domain
PIGPPANF_01485 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PIGPPANF_01486 7.6e-150 corA P CorA-like protein
PIGPPANF_01487 9.6e-62 yjqA S Bacterial PH domain
PIGPPANF_01488 5.8e-95 thiT S Thiamine transporter
PIGPPANF_01489 9.5e-150 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PIGPPANF_01490 1.8e-196 yjbB G Permeases of the major facilitator superfamily
PIGPPANF_01491 5.2e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PIGPPANF_01492 9.6e-118 ywaF S Integral membrane protein (intg_mem_TP0381)
PIGPPANF_01493 1e-251 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PIGPPANF_01496 1.7e-154 cjaA ET ABC transporter substrate-binding protein
PIGPPANF_01497 2e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
PIGPPANF_01498 3e-106 P ABC transporter (Permease
PIGPPANF_01499 3.9e-114 papP P ABC transporter (Permease
PIGPPANF_01501 5.4e-192 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PIGPPANF_01502 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
PIGPPANF_01503 0.0 copA 3.6.3.54 P P-type ATPase
PIGPPANF_01504 2.1e-73 copY K negative regulation of transcription, DNA-templated
PIGPPANF_01507 6.6e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PIGPPANF_01508 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PIGPPANF_01509 1.7e-97 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
PIGPPANF_01510 1.2e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PIGPPANF_01511 8.7e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PIGPPANF_01512 3e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
PIGPPANF_01513 3.1e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PIGPPANF_01514 1.2e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
PIGPPANF_01515 3.5e-120 yujD V lipoprotein transporter activity
PIGPPANF_01516 0.0 S bacteriocin-associated integral membrane protein
PIGPPANF_01517 2.1e-19 S Bacteriocin (Lactococcin_972)
PIGPPANF_01518 1.1e-57
PIGPPANF_01519 0.0 ctpE P E1-E2 ATPase
PIGPPANF_01520 8.9e-47
PIGPPANF_01521 9.3e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
PIGPPANF_01522 1.9e-286 ahpF O alkyl hydroperoxide reductase
PIGPPANF_01524 4.2e-95 S reductase
PIGPPANF_01525 3.9e-72 badR K Transcriptional regulator, marr family
PIGPPANF_01526 7.9e-35 XK27_02060 S Transglycosylase associated protein
PIGPPANF_01527 1.1e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PIGPPANF_01528 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIGPPANF_01533 4.9e-111 mreC M Involved in formation and maintenance of cell shape
PIGPPANF_01534 1.1e-81 mreD M rod shape-determining protein MreD
PIGPPANF_01535 9.7e-86 usp 3.5.1.28 CBM50 S CHAP domain
PIGPPANF_01536 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIGPPANF_01537 4.4e-214 araT 2.6.1.1 E Aminotransferase
PIGPPANF_01538 1.7e-137 recO L Involved in DNA repair and RecF pathway recombination
PIGPPANF_01539 1.3e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PIGPPANF_01540 3.1e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIGPPANF_01541 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PIGPPANF_01542 4.3e-87 V abc transporter atp-binding protein
PIGPPANF_01543 1.4e-14
PIGPPANF_01545 1.1e-73 K Transcriptional regulatory protein, C terminal
PIGPPANF_01546 8.9e-65 2.7.13.3 T Histidine kinase
PIGPPANF_01547 3.8e-91 maa 2.3.1.79 GK Maltose O-acetyltransferase
PIGPPANF_01548 6.5e-64 rmaI K Transcriptional regulator, MarR family
PIGPPANF_01549 2.6e-234 EGP Major facilitator Superfamily
PIGPPANF_01550 9.9e-127 XK27_00785 S CAAX protease self-immunity
PIGPPANF_01551 3e-119 mleR K malolactic fermentation system
PIGPPANF_01552 1.8e-46 K Helix-turn-helix
PIGPPANF_01553 1e-122 V abc transporter atp-binding protein
PIGPPANF_01554 2e-203 P FtsX-like permease family
PIGPPANF_01555 7.5e-42 S Sugar efflux transporter for intercellular exchange
PIGPPANF_01556 4.6e-85 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PIGPPANF_01557 5.2e-176 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
PIGPPANF_01558 1.8e-164 ET ABC transporter substrate-binding protein
PIGPPANF_01559 1.3e-109 ytmL P ABC transporter (Permease
PIGPPANF_01560 2.1e-112 yxeN P ABC transporter, permease protein
PIGPPANF_01561 2.1e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
PIGPPANF_01562 0.0 S dextransucrase activity
PIGPPANF_01563 3.3e-213 yfnA E amino acid
PIGPPANF_01564 5.7e-50 XK27_01300 P Protein conserved in bacteria
PIGPPANF_01565 3.7e-47 S Carbohydrate-binding domain-containing protein Cthe_2159
PIGPPANF_01566 2.4e-45 S Carbohydrate-binding domain-containing protein Cthe_2159
PIGPPANF_01567 1.1e-16 csbD S CsbD-like
PIGPPANF_01568 3.4e-104 S Protein of unknown function (DUF421)
PIGPPANF_01569 1.8e-59 S Protein of unknown function (DUF3290)
PIGPPANF_01570 5.1e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
PIGPPANF_01571 2.8e-233 brnQ E Component of the transport system for branched-chain amino acids
PIGPPANF_01572 8.8e-181 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PIGPPANF_01574 7.1e-245 norM V Multidrug efflux pump
PIGPPANF_01575 3.7e-143 K sequence-specific DNA binding
PIGPPANF_01576 3e-274 V (ABC) transporter
PIGPPANF_01577 1.1e-223 pbuX F xanthine permease
PIGPPANF_01578 9.7e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PIGPPANF_01579 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PIGPPANF_01580 7.6e-164 T Histidine kinase
PIGPPANF_01581 6.4e-134 macB2 V ABC transporter, ATP-binding protein
PIGPPANF_01582 0.0 V ABC transporter (permease)
PIGPPANF_01583 1.8e-92 XK27_05000 S metal cluster binding
PIGPPANF_01584 2e-30 liaI KT membrane
PIGPPANF_01585 5.4e-15 liaI KT membrane
PIGPPANF_01586 1.5e-155 XK27_09825 V abc transporter atp-binding protein
PIGPPANF_01587 3.4e-132 yvfS V Transporter
PIGPPANF_01588 1.5e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
PIGPPANF_01589 1.5e-164 yocS S Transporter
PIGPPANF_01590 0.0 hscC O Belongs to the heat shock protein 70 family
PIGPPANF_01591 3.8e-230 anK3 G response to abiotic stimulus
PIGPPANF_01593 3.1e-213 2.4.1.276 GT1 CG transferase activity, transferring hexosyl groups
PIGPPANF_01594 8.8e-108
PIGPPANF_01595 1.6e-197 ugcG 2.4.1.80 GT21 M transferase activity, transferring glycosyl groups
PIGPPANF_01596 3.5e-103 1.1.1.105 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PIGPPANF_01597 3.5e-233 2.4.1.276 GT1 CG Glycosyltransferase family 28 C-terminal domain
PIGPPANF_01598 1.2e-180 ybjS 1.1.1.133, 5.1.3.13 M NAD dependent epimerase dehydratase family protein
PIGPPANF_01599 5.1e-153 gumP S Metallo-beta-lactamase superfamily
PIGPPANF_01600 7.2e-239 6.2.1.30 H Coenzyme F390 synthetase
PIGPPANF_01601 1.3e-171 fabH 2.3.1.180 I synthase III
PIGPPANF_01604 1.5e-158 XK27_09825 V abc transporter atp-binding protein
PIGPPANF_01605 2.9e-131 yvfS V ABC-2 type transporter
PIGPPANF_01606 1.1e-190 desK 2.7.13.3 T Histidine kinase
PIGPPANF_01607 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PIGPPANF_01608 3.2e-201 S Protein of unknown function DUF262
PIGPPANF_01609 7.9e-126 S Protein of unknown function DUF262
PIGPPANF_01610 4.3e-85 yfjR K regulation of single-species biofilm formation
PIGPPANF_01613 1.5e-183 S AAA domain, putative AbiEii toxin, Type IV TA system
PIGPPANF_01614 0.0 M domain protein
PIGPPANF_01615 3.6e-12
PIGPPANF_01617 1.3e-57 pnuC H nicotinamide mononucleotide transporter
PIGPPANF_01618 8.6e-67 K Transcriptional regulator
PIGPPANF_01619 1.1e-176 1.1.1.1 C nadph quinone reductase
PIGPPANF_01620 5.2e-153 I Alpha/beta hydrolase family
PIGPPANF_01621 9.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PIGPPANF_01622 7.6e-39
PIGPPANF_01623 3e-57 S Protein of unknown function with HXXEE motif
PIGPPANF_01624 1.5e-92 K Transcriptional regulator, TetR family
PIGPPANF_01625 5.6e-153 czcD P cation diffusion facilitator family transporter
PIGPPANF_01626 2.8e-191 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PIGPPANF_01627 1.9e-161 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
PIGPPANF_01628 1.2e-310 S dextransucrase activity
PIGPPANF_01629 0.0 M Putative cell wall binding repeat
PIGPPANF_01630 6.7e-228 S dextransucrase activity
PIGPPANF_01631 1.8e-96
PIGPPANF_01633 9e-167 fhuR K transcriptional regulator (lysR family)
PIGPPANF_01634 2.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PIGPPANF_01635 2.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PIGPPANF_01636 1.8e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIGPPANF_01637 3.1e-221 pyrP F uracil Permease
PIGPPANF_01638 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PIGPPANF_01639 4.6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
PIGPPANF_01640 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
PIGPPANF_01641 2.7e-124 2.1.1.223 S Putative SAM-dependent methyltransferase
PIGPPANF_01642 1.3e-179 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PIGPPANF_01643 5.8e-121 macB V ABC transporter, ATP-binding protein
PIGPPANF_01644 1.2e-211 V permease protein
PIGPPANF_01645 0.0 L SNF2 family N-terminal domain
PIGPPANF_01646 1.4e-71 S Domain of unknown function (DUF4391)
PIGPPANF_01647 8.2e-234 mod 2.1.1.72 L DNA methylase
PIGPPANF_01649 0.0 res 3.1.21.5 L restriction endonuclease
PIGPPANF_01650 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PIGPPANF_01651 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PIGPPANF_01653 1.3e-65 traG U COG3505 Type IV secretory pathway, VirD4 components
PIGPPANF_01654 2.5e-104 XK27_00530 M CHAP domain protein
PIGPPANF_01655 8.5e-102 abiGI K Transcriptional regulator, AbiEi antitoxin
PIGPPANF_01656 1.1e-270 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
PIGPPANF_01657 8.7e-28 K DNA-binding transcription factor activity
PIGPPANF_01658 0.0 mdlB V abc transporter atp-binding protein
PIGPPANF_01659 0.0 lmrA V abc transporter atp-binding protein
PIGPPANF_01660 2.1e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PIGPPANF_01661 1.8e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PIGPPANF_01662 2.8e-214 T signal transduction protein with a C-terminal ATPase domain
PIGPPANF_01663 4.5e-129 rr02 KT response regulator
PIGPPANF_01664 2.5e-164 V ABC transporter
PIGPPANF_01665 7.7e-121 sagI S ABC-2 type transporter
PIGPPANF_01666 6.9e-197 yceA S Belongs to the UPF0176 family
PIGPPANF_01667 1.6e-28 XK27_00085 K Transcriptional
PIGPPANF_01668 7.4e-22
PIGPPANF_01669 4.7e-132 deoD_1 2.4.2.3 F Phosphorylase superfamily
PIGPPANF_01670 8.7e-114 S VIT family
PIGPPANF_01671 2.5e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PIGPPANF_01672 6.5e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PIGPPANF_01673 2.5e-195 ald 1.4.1.1 C Belongs to the AlaDH PNT family
PIGPPANF_01675 2.8e-124 E alpha/beta hydrolase fold
PIGPPANF_01676 5.5e-50 T peptidase
PIGPPANF_01677 1.3e-109 T Response regulator receiver domain protein
PIGPPANF_01678 3e-179 ybdK T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PIGPPANF_01679 1.7e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PIGPPANF_01680 1.6e-19 ytjP 3.5.1.18 E Dipeptidase
PIGPPANF_01681 1.1e-97 ET Bacterial extracellular solute-binding proteins, family 3
PIGPPANF_01682 2.5e-59 K Acetyltransferase (GNAT) domain
PIGPPANF_01684 3e-152 1.8.5.7 O Glutathione S-transferase
PIGPPANF_01685 4.3e-173 1.8.5.7 O Glutathione S-transferase, C-terminal domain
PIGPPANF_01686 5.1e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PIGPPANF_01687 1.5e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PIGPPANF_01688 3.4e-167 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PIGPPANF_01689 3.6e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PIGPPANF_01690 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
PIGPPANF_01691 1.1e-227 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PIGPPANF_01692 6.5e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
PIGPPANF_01693 7.8e-23
PIGPPANF_01694 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PIGPPANF_01695 0.0 U protein secretion
PIGPPANF_01696 4.4e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
PIGPPANF_01697 4.5e-244 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PIGPPANF_01698 5.6e-55 XK27_13030
PIGPPANF_01699 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PIGPPANF_01700 9e-146 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PIGPPANF_01701 8e-191 S Protein of unknown function (DUF3114)
PIGPPANF_01702 4.1e-29 pspC KT PspC domain protein
PIGPPANF_01703 2.6e-118 yqfA K protein, Hemolysin III
PIGPPANF_01704 3e-78 K hmm pf08876
PIGPPANF_01705 2.3e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PIGPPANF_01706 1e-210 mvaS 2.3.3.10 I synthase
PIGPPANF_01707 3.2e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PIGPPANF_01708 1.3e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PIGPPANF_01709 9.7e-22
PIGPPANF_01710 9.8e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PIGPPANF_01711 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PIGPPANF_01712 1.7e-249 mmuP E amino acid
PIGPPANF_01713 3.9e-165 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
PIGPPANF_01714 2.2e-30 S Domain of unknown function (DUF1912)
PIGPPANF_01715 3.7e-13 L Helix-hairpin-helix DNA-binding motif class 1
PIGPPANF_01716 5.6e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIGPPANF_01717 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIGPPANF_01719 5.6e-12
PIGPPANF_01720 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIGPPANF_01721 1.7e-198 ilvE 2.6.1.42 E Aminotransferase
PIGPPANF_01722 2.2e-16 S Protein of unknown function (DUF2969)
PIGPPANF_01725 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
PIGPPANF_01728 2.1e-106 S Domain of Unknown Function with PDB structure (DUF3862)
PIGPPANF_01729 1.4e-116 M Pfam SNARE associated Golgi protein
PIGPPANF_01730 7.3e-228 murN 2.3.2.16 V FemAB family
PIGPPANF_01731 7.5e-172 S oxidoreductase
PIGPPANF_01732 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
PIGPPANF_01733 2.2e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PIGPPANF_01734 0.0 clpE O Belongs to the ClpA ClpB family
PIGPPANF_01735 1.7e-179 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PIGPPANF_01736 1e-34 ykuJ S protein conserved in bacteria
PIGPPANF_01737 1.7e-117 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
PIGPPANF_01738 9.3e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
PIGPPANF_01739 1e-76 feoA P FeoA domain protein
PIGPPANF_01740 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PIGPPANF_01741 6.6e-08
PIGPPANF_01742 8.8e-147 I Alpha/beta hydrolase family
PIGPPANF_01743 1.7e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PIGPPANF_01744 2.6e-144 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PIGPPANF_01745 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
PIGPPANF_01746 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PIGPPANF_01747 1.7e-143 licT K antiterminator
PIGPPANF_01748 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PIGPPANF_01749 6.4e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PIGPPANF_01750 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PIGPPANF_01751 3.9e-145 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PIGPPANF_01752 1.5e-93 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PIGPPANF_01753 3.8e-221 mdtG EGP Major facilitator Superfamily
PIGPPANF_01754 2e-33 secG U Preprotein translocase subunit SecG
PIGPPANF_01755 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PIGPPANF_01756 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PIGPPANF_01757 7.6e-274 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PIGPPANF_01758 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
PIGPPANF_01759 1.1e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
PIGPPANF_01760 1.9e-181 ccpA K Catabolite control protein A
PIGPPANF_01761 4.9e-196 yyaQ S YjbR
PIGPPANF_01762 6.8e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PIGPPANF_01763 8.7e-78 yueI S Protein of unknown function (DUF1694)
PIGPPANF_01764 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PIGPPANF_01765 4.6e-25 WQ51_00785
PIGPPANF_01766 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PIGPPANF_01767 8.1e-213 ywbD 2.1.1.191 J Methyltransferase
PIGPPANF_01768 1.4e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PIGPPANF_01769 3.3e-155 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PIGPPANF_01770 3.3e-200 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PIGPPANF_01771 1.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PIGPPANF_01772 5.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PIGPPANF_01773 4.2e-53 yheA S Belongs to the UPF0342 family
PIGPPANF_01774 2.4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PIGPPANF_01775 3.5e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PIGPPANF_01776 5.5e-78 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PIGPPANF_01777 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
PIGPPANF_01778 1.3e-244 msrR K Transcriptional regulator
PIGPPANF_01779 6.5e-152 ydiA P C4-dicarboxylate transporter malic acid transport protein
PIGPPANF_01780 2.5e-200 I acyl-CoA dehydrogenase
PIGPPANF_01781 2e-97 mip S hydroperoxide reductase activity
PIGPPANF_01782 7.9e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIGPPANF_01783 2.6e-52 K TfoX N-terminal domain
PIGPPANF_01784 1.2e-18 S alpha beta
PIGPPANF_01785 4.8e-65 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
PIGPPANF_01786 4e-96
PIGPPANF_01788 7.3e-104 K Transcriptional regulator
PIGPPANF_01789 3.1e-130 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
PIGPPANF_01790 1.4e-260 6.1.1.6 S Psort location CytoplasmicMembrane, score
PIGPPANF_01791 8.9e-28 S Protein of unknown function (DUF1648)
PIGPPANF_01792 2.3e-51 K Transcriptional regulator
PIGPPANF_01793 1.8e-120 S CAAX amino terminal protease family protein
PIGPPANF_01795 6.4e-24 L PFAM Integrase catalytic region
PIGPPANF_01796 2.4e-82 3.1.3.16 S Protein of unknown function (DUF1643)
PIGPPANF_01797 1.1e-117
PIGPPANF_01798 6.1e-132 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PIGPPANF_01799 1.3e-131 S Domain of unknown function (DUF4336)
PIGPPANF_01800 1.3e-202 yeaN P transporter
PIGPPANF_01801 4.2e-150 yitS S EDD domain protein, DegV family
PIGPPANF_01802 1.4e-93 XK27_08140 K Bacterial regulatory proteins, tetR family
PIGPPANF_01803 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PIGPPANF_01804 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PIGPPANF_01805 4.5e-175 XK27_08075 M glycosyl transferase family 2
PIGPPANF_01806 1.1e-96 S Carbohydrate-binding domain-containing protein Cthe_2159
PIGPPANF_01807 6.3e-145 P molecular chaperone
PIGPPANF_01808 9.3e-92 XK27_05505 S Psort location CytoplasmicMembrane, score
PIGPPANF_01810 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PIGPPANF_01811 1.1e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PIGPPANF_01812 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PIGPPANF_01813 2.2e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PIGPPANF_01814 2.8e-108 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PIGPPANF_01815 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PIGPPANF_01816 2.3e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PIGPPANF_01817 8e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PIGPPANF_01818 1.2e-180 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PIGPPANF_01819 1.4e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PIGPPANF_01820 8.7e-58 XK27_08085
PIGPPANF_01821 4e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PIGPPANF_01822 8.7e-136 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
PIGPPANF_01823 4.3e-115 ylfI S tigr01906
PIGPPANF_01824 1e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PIGPPANF_01825 3.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
PIGPPANF_01826 2.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
PIGPPANF_01827 8.4e-30 KT response to antibiotic
PIGPPANF_01829 9.6e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PIGPPANF_01830 5.4e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PIGPPANF_01831 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PIGPPANF_01832 1.3e-254 S phospholipase Carboxylesterase
PIGPPANF_01833 1e-193 yurR 1.4.5.1 E oxidoreductase
PIGPPANF_01834 8.2e-143 zupT P Mediates zinc uptake. May also transport other divalent cations
PIGPPANF_01835 5.4e-144 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PIGPPANF_01836 2.8e-120 trmK 2.1.1.217 S SAM-dependent methyltransferase
PIGPPANF_01837 1.3e-64 gtrA S GtrA-like protein
PIGPPANF_01838 3.7e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PIGPPANF_01839 1.1e-162 ybbR S Protein conserved in bacteria
PIGPPANF_01840 7.9e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PIGPPANF_01841 3.8e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
PIGPPANF_01842 1.2e-146 cobQ S glutamine amidotransferase
PIGPPANF_01843 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PIGPPANF_01844 3.3e-132 pip 1.11.1.10 S Alpha beta hydrolase
PIGPPANF_01845 2.7e-39 MA20_06245 S yiaA/B two helix domain
PIGPPANF_01846 0.0 uup S abc transporter atp-binding protein
PIGPPANF_01847 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
PIGPPANF_01848 4.3e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
PIGPPANF_01849 2.3e-223 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
PIGPPANF_01850 2.7e-153 XK27_05675 S Esterase
PIGPPANF_01851 3.9e-161 XK27_05670 S Putative esterase
PIGPPANF_01852 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
PIGPPANF_01853 5.5e-270 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PIGPPANF_01854 2.2e-162 metF 1.5.1.20 E reductase
PIGPPANF_01855 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PIGPPANF_01857 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
PIGPPANF_01858 0.0 3.6.3.8 P cation transport ATPase
PIGPPANF_01859 6.3e-243 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PIGPPANF_01860 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIGPPANF_01861 5.6e-236 dltB M Membrane protein involved in D-alanine export
PIGPPANF_01862 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIGPPANF_01863 0.0 XK27_10035 V abc transporter atp-binding protein
PIGPPANF_01864 3.5e-292 yfiB1 V abc transporter atp-binding protein
PIGPPANF_01865 1.4e-99 pvaA M lytic transglycosylase activity
PIGPPANF_01866 4.2e-178 ndpA S 37-kD nucleoid-associated bacterial protein
PIGPPANF_01867 1.1e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PIGPPANF_01868 2.7e-103 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PIGPPANF_01869 2.7e-141 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PIGPPANF_01870 2.4e-187 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PIGPPANF_01871 3.9e-110 tdk 2.7.1.21 F thymidine kinase
PIGPPANF_01872 7.1e-181 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PIGPPANF_01873 1.3e-150 gst O Glutathione S-transferase
PIGPPANF_01874 8.4e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
PIGPPANF_01875 2.9e-168 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PIGPPANF_01876 4.4e-45 rpmE2 J 50S ribosomal protein L31
PIGPPANF_01877 6.9e-201 mntH P Mn2 and Fe2 transporters of the NRAMP family
PIGPPANF_01878 1.8e-07 mntH P Mn2 and Fe2 transporters of the NRAMP family
PIGPPANF_01879 7.9e-161 ypuA S secreted protein
PIGPPANF_01880 8.2e-72 yaeR E COG0346 Lactoylglutathione lyase and related lyases
PIGPPANF_01881 3.9e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
PIGPPANF_01882 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIGPPANF_01883 2.2e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PIGPPANF_01884 3.9e-254 noxE P NADH oxidase
PIGPPANF_01885 4.3e-294 yfmM S abc transporter atp-binding protein
PIGPPANF_01886 4.1e-79 XK27_01265 S ECF-type riboflavin transporter, S component
PIGPPANF_01887 5.3e-145 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
PIGPPANF_01888 1.6e-83 S ECF-type riboflavin transporter, S component
PIGPPANF_01890 2.8e-235 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PIGPPANF_01891 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
PIGPPANF_01893 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIGPPANF_01894 7.8e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIGPPANF_01895 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PIGPPANF_01896 1e-22 WQ51_00220 K Helix-turn-helix domain
PIGPPANF_01897 5.2e-85 S Protein of unknown function (DUF3278)
PIGPPANF_01898 0.0 smc D Required for chromosome condensation and partitioning
PIGPPANF_01899 7.1e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PIGPPANF_01900 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PIGPPANF_01901 6.2e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PIGPPANF_01902 1.7e-75 alkD L DNA alkylation repair enzyme
PIGPPANF_01903 2.5e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PIGPPANF_01904 2.1e-132
PIGPPANF_01906 1.7e-246 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
PIGPPANF_01907 1e-193 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
PIGPPANF_01908 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIGPPANF_01909 9.3e-26 epuA S DNA-directed RNA polymerase subunit beta
PIGPPANF_01910 8.5e-154 endA F DNA RNA non-specific endonuclease

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)