ORF_ID e_value Gene_name EC_number CAZy COGs Description
HEJKOICF_00001 2.8e-55 tlpA2 L Transposase IS200 like
HEJKOICF_00002 8.4e-187 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEJKOICF_00003 2.9e-226 mtnE 2.6.1.83 E Aminotransferase
HEJKOICF_00004 2.3e-147 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HEJKOICF_00005 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEJKOICF_00006 2.6e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HEJKOICF_00007 9.6e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEJKOICF_00008 1e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEJKOICF_00009 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HEJKOICF_00010 4.1e-53 KT PspC domain protein
HEJKOICF_00011 5e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEJKOICF_00012 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEJKOICF_00013 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEJKOICF_00014 8e-128 comFC S Competence protein
HEJKOICF_00015 5.5e-250 comFA L Helicase C-terminal domain protein
HEJKOICF_00016 2.2e-111 yvyE 3.4.13.9 S YigZ family
HEJKOICF_00017 6.4e-38
HEJKOICF_00018 0.0 ydaO E amino acid
HEJKOICF_00019 9.8e-289 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEJKOICF_00020 7.4e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEJKOICF_00021 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEJKOICF_00022 0.0 uup S ABC transporter, ATP-binding protein
HEJKOICF_00023 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEJKOICF_00024 9.7e-92 bioY S BioY family
HEJKOICF_00025 5.8e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HEJKOICF_00026 1e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HEJKOICF_00027 1.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEJKOICF_00028 4.6e-263 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HEJKOICF_00029 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEJKOICF_00030 1.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEJKOICF_00031 6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEJKOICF_00032 2.7e-129 IQ reductase
HEJKOICF_00033 2.8e-171 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HEJKOICF_00034 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEJKOICF_00035 6.3e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEJKOICF_00036 8.7e-75 marR K Transcriptional regulator, MarR family
HEJKOICF_00037 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEJKOICF_00039 1.2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEJKOICF_00040 2.5e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HEJKOICF_00041 3.2e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HEJKOICF_00042 7.6e-216 arcT 2.6.1.1 E Aminotransferase
HEJKOICF_00043 3.9e-220 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HEJKOICF_00044 1.1e-259 E Arginine ornithine antiporter
HEJKOICF_00045 8.2e-240 arcA 3.5.3.6 E Arginine
HEJKOICF_00046 1.4e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HEJKOICF_00047 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEJKOICF_00048 1.8e-148 KT YcbB domain
HEJKOICF_00049 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEJKOICF_00050 2.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HEJKOICF_00051 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HEJKOICF_00052 3.1e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HEJKOICF_00053 3.3e-146 fat 3.1.2.21 I Acyl-ACP thioesterase
HEJKOICF_00054 8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEJKOICF_00055 7.6e-55 yabA L Involved in initiation control of chromosome replication
HEJKOICF_00056 4.9e-193 holB 2.7.7.7 L DNA polymerase III
HEJKOICF_00057 1.2e-52 yaaQ S Cyclic-di-AMP receptor
HEJKOICF_00058 6e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEJKOICF_00059 2.4e-21 S Protein of unknown function (DUF2508)
HEJKOICF_00060 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEJKOICF_00061 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEJKOICF_00062 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEJKOICF_00064 6.3e-80 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEJKOICF_00065 2e-35 nrdH O Glutaredoxin
HEJKOICF_00066 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEJKOICF_00067 8.6e-195 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEJKOICF_00068 4.6e-247 brnQ U Component of the transport system for branched-chain amino acids
HEJKOICF_00070 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HEJKOICF_00071 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HEJKOICF_00072 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HEJKOICF_00073 4.1e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HEJKOICF_00074 5.6e-272 cydA 1.10.3.14 C ubiquinol oxidase
HEJKOICF_00075 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEJKOICF_00076 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEJKOICF_00077 1.7e-243 steT E amino acid
HEJKOICF_00078 9.7e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEJKOICF_00079 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEJKOICF_00080 5.9e-97 nusG K Participates in transcription elongation, termination and antitermination
HEJKOICF_00081 2.4e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEJKOICF_00082 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEJKOICF_00083 1.1e-104 sigH K Belongs to the sigma-70 factor family
HEJKOICF_00084 5.2e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEJKOICF_00085 1.2e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEJKOICF_00086 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEJKOICF_00087 7.8e-100 ywlG S Belongs to the UPF0340 family
HEJKOICF_00088 2.8e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEJKOICF_00089 2.3e-204 yacL S domain protein
HEJKOICF_00090 5.6e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEJKOICF_00091 1.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HEJKOICF_00092 4.2e-55 HA62_12640 S GCN5-related N-acetyl-transferase
HEJKOICF_00093 1.3e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HEJKOICF_00094 1.1e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
HEJKOICF_00095 4.9e-262 pepC 3.4.22.40 E Peptidase C1-like family
HEJKOICF_00096 1.3e-167 I alpha/beta hydrolase fold
HEJKOICF_00097 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEJKOICF_00098 2.3e-168 mleP2 S Sodium Bile acid symporter family
HEJKOICF_00099 1.2e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HEJKOICF_00100 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HEJKOICF_00102 2.4e-83 ydcK S Belongs to the SprT family
HEJKOICF_00103 0.0 yhgF K Tex-like protein N-terminal domain protein
HEJKOICF_00104 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEJKOICF_00105 2.9e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEJKOICF_00106 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
HEJKOICF_00107 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HEJKOICF_00108 1.1e-115
HEJKOICF_00111 2.1e-165 yjjH S Calcineurin-like phosphoesterase
HEJKOICF_00112 3.7e-258 dtpT U amino acid peptide transporter
HEJKOICF_00113 1.2e-167 D nuclear chromosome segregation
HEJKOICF_00117 4e-22
HEJKOICF_00118 2.7e-247 cycA E Amino acid permease
HEJKOICF_00119 7.4e-85 perR P Belongs to the Fur family
HEJKOICF_00120 5.2e-254 EGP Major facilitator Superfamily
HEJKOICF_00121 1.8e-98 tag 3.2.2.20 L glycosylase
HEJKOICF_00122 1.3e-51
HEJKOICF_00123 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEJKOICF_00124 4.8e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEJKOICF_00125 3.4e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEJKOICF_00126 1.4e-127 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
HEJKOICF_00127 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEJKOICF_00128 2.6e-42
HEJKOICF_00129 3.6e-299 ytgP S Polysaccharide biosynthesis protein
HEJKOICF_00130 1.5e-62 3.2.1.23 S Domain of unknown function DUF302
HEJKOICF_00131 1.3e-157 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEJKOICF_00132 3.8e-273 pepV 3.5.1.18 E dipeptidase PepV
HEJKOICF_00133 5.1e-87 uspA T Belongs to the universal stress protein A family
HEJKOICF_00134 5.4e-256 S Putative peptidoglycan binding domain
HEJKOICF_00135 3.4e-160 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEJKOICF_00136 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
HEJKOICF_00137 2.3e-110
HEJKOICF_00138 9.9e-183 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HEJKOICF_00139 1.1e-119 S CAAX protease self-immunity
HEJKOICF_00140 2.5e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEJKOICF_00141 1.3e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HEJKOICF_00142 1.5e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HEJKOICF_00143 2.2e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HEJKOICF_00144 1.2e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HEJKOICF_00145 5.3e-201 folP 2.5.1.15 H dihydropteroate synthase
HEJKOICF_00147 1.7e-36
HEJKOICF_00149 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HEJKOICF_00150 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEJKOICF_00151 9.8e-56 yheA S Belongs to the UPF0342 family
HEJKOICF_00152 5.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HEJKOICF_00153 2.6e-151 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEJKOICF_00155 1.4e-77 hit FG histidine triad
HEJKOICF_00156 2.3e-133 ecsA V ABC transporter, ATP-binding protein
HEJKOICF_00157 8.6e-210 ecsB U ABC transporter
HEJKOICF_00158 2.3e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEJKOICF_00159 5.1e-59 ytzB S Small secreted protein
HEJKOICF_00160 3.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HEJKOICF_00161 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEJKOICF_00162 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HEJKOICF_00163 1.8e-114 ybhL S Belongs to the BI1 family
HEJKOICF_00164 1.8e-23 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HEJKOICF_00165 1.8e-56 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HEJKOICF_00167 2.1e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HEJKOICF_00168 1.3e-24 phaG GT1 I carboxylic ester hydrolase activity
HEJKOICF_00169 1.2e-62 K Transcriptional regulator
HEJKOICF_00170 1.2e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEJKOICF_00171 4.3e-155 metQ_4 P Belongs to the nlpA lipoprotein family
HEJKOICF_00172 9.5e-19 tnp L MULE transposase domain
HEJKOICF_00173 1.2e-263 npr 1.11.1.1 C NADH oxidase
HEJKOICF_00174 3.8e-19 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HEJKOICF_00175 1.5e-40 L PFAM transposase, IS4 family protein
HEJKOICF_00176 7.7e-85 L PFAM transposase, IS4 family protein
HEJKOICF_00177 7.6e-48 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HEJKOICF_00178 9.9e-100 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEJKOICF_00179 2.4e-118 L Integrase core domain
HEJKOICF_00180 4.7e-41 L Integrase core domain
HEJKOICF_00181 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HEJKOICF_00182 3.1e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
HEJKOICF_00183 2.9e-85 macB_3 V FtsX-like permease family
HEJKOICF_00184 3.8e-85 macB_3 V FtsX-like permease family
HEJKOICF_00185 7.6e-42 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEJKOICF_00186 1.5e-76 yphH S Cupin domain
HEJKOICF_00187 9.2e-23 L Helix-turn-helix domain
HEJKOICF_00188 4.8e-165 L PFAM Integrase catalytic region
HEJKOICF_00189 1.1e-289 L Transposase IS66 family
HEJKOICF_00190 4.4e-23 XK27_01125 L PFAM IS66 Orf2 family protein
HEJKOICF_00192 6.4e-179 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEJKOICF_00193 3.5e-48 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEJKOICF_00194 1.5e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HEJKOICF_00196 1.2e-54
HEJKOICF_00197 1.7e-176 prmA J Ribosomal protein L11 methyltransferase
HEJKOICF_00198 2.2e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEJKOICF_00199 4.4e-58
HEJKOICF_00200 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEJKOICF_00201 2.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEJKOICF_00202 3.5e-85 slyA K Transcriptional regulator
HEJKOICF_00203 1e-218 metC1 2.5.1.48, 4.4.1.8 E cystathionine
HEJKOICF_00204 4e-209 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HEJKOICF_00206 2.4e-67 yxeM ET Bacterial periplasmic substrate-binding proteins
HEJKOICF_00207 5.4e-47 yxeL K acetyltransferase
HEJKOICF_00208 2.2e-70 yxeN U ABC transporter, permease protein
HEJKOICF_00209 1.2e-78 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
HEJKOICF_00210 5e-146 3.5.1.47 E Peptidase dimerisation domain
HEJKOICF_00211 1.1e-171 pcaB 4.3.2.2 F Adenylosuccinate lyase C-terminus
HEJKOICF_00212 8.8e-91 yxeQ S MmgE/PrpD family
HEJKOICF_00214 1.2e-112 papP P ABC transporter, permease protein
HEJKOICF_00215 1.7e-93 P ABC transporter permease
HEJKOICF_00216 3.9e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HEJKOICF_00217 3.1e-153 cjaA ET ABC transporter substrate-binding protein
HEJKOICF_00218 2.7e-137 IQ KR domain
HEJKOICF_00219 1.5e-211 hom1 1.1.1.3 E Homoserine dehydrogenase
HEJKOICF_00220 6.9e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HEJKOICF_00221 1.7e-244 mmuP E amino acid
HEJKOICF_00222 1.3e-173 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HEJKOICF_00223 1.4e-169 yniA G Phosphotransferase enzyme family
HEJKOICF_00224 6.3e-174 lytH 3.5.1.28 M Ami_3
HEJKOICF_00225 2.1e-196 6.3.1.20 H Lipoate-protein ligase
HEJKOICF_00226 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
HEJKOICF_00227 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HEJKOICF_00228 5.1e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
HEJKOICF_00229 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HEJKOICF_00230 4.6e-71 yqeY S YqeY-like protein
HEJKOICF_00231 1.1e-178 phoH T phosphate starvation-inducible protein PhoH
HEJKOICF_00232 1.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEJKOICF_00233 2.5e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HEJKOICF_00234 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEJKOICF_00235 2.9e-156 recO L Involved in DNA repair and RecF pathway recombination
HEJKOICF_00236 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HEJKOICF_00237 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HEJKOICF_00238 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEJKOICF_00239 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEJKOICF_00240 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEJKOICF_00241 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
HEJKOICF_00242 1.6e-90 S PAS domain
HEJKOICF_00243 3.6e-71 macB_3 V FtsX-like permease family
HEJKOICF_00244 1.5e-39 L Transposase
HEJKOICF_00245 4.4e-138 IQ reductase
HEJKOICF_00246 2.7e-15 L Helix-turn-helix domain
HEJKOICF_00247 1.4e-107 tnp L MULE transposase domain
HEJKOICF_00248 1.1e-50 L Helix-turn-helix domain
HEJKOICF_00249 3.5e-23 tlpA2 L Transposase IS200 like
HEJKOICF_00251 2e-23 2.1.1.144, 2.1.1.197 S DREV methyltransferase
HEJKOICF_00254 1.2e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEJKOICF_00255 3.1e-187 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEJKOICF_00256 1.8e-104 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HEJKOICF_00257 5.4e-153 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEJKOICF_00258 4.5e-165 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
HEJKOICF_00259 3e-84 S Membrane protein involved in the export of O-antigen and teichoic acid
HEJKOICF_00260 1.6e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HEJKOICF_00261 9.8e-46 M Glycosyl transferase family 2
HEJKOICF_00262 1.3e-09
HEJKOICF_00263 4.6e-75 M Glycosyl transferase 4-like
HEJKOICF_00264 6e-79 wceM M Glycosyltransferase like family 2
HEJKOICF_00265 2.1e-16 lsgF M Glycosyl transferase family 2
HEJKOICF_00266 1.2e-94 tuaA M Bacterial sugar transferase
HEJKOICF_00267 7.4e-132 cps2D 5.1.3.2 M RmlD substrate binding domain
HEJKOICF_00268 5.1e-139 ywqE 3.1.3.48 GM PHP domain protein
HEJKOICF_00269 1.9e-114 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HEJKOICF_00270 1.8e-131 epsB M biosynthesis protein
HEJKOICF_00271 2.8e-169 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HEJKOICF_00272 6.5e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEJKOICF_00273 2.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
HEJKOICF_00274 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEJKOICF_00275 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
HEJKOICF_00276 1.6e-146 spo0J K Belongs to the ParB family
HEJKOICF_00277 3.9e-157 noc K Belongs to the ParB family
HEJKOICF_00278 1.7e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HEJKOICF_00279 2.2e-144 rihC 3.2.2.1 F Nucleoside
HEJKOICF_00280 8.4e-213 nupG F Nucleoside transporter
HEJKOICF_00281 4.2e-245 cycA E Amino acid permease
HEJKOICF_00282 1e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HEJKOICF_00283 2.8e-226 glnP P ABC transporter
HEJKOICF_00285 4.2e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEJKOICF_00287 5.7e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEJKOICF_00288 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HEJKOICF_00289 8.7e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEJKOICF_00291 8.3e-298 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEJKOICF_00292 1.2e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
HEJKOICF_00293 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEJKOICF_00294 1.6e-241 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEJKOICF_00295 8.3e-123 iolS C Aldo keto reductase
HEJKOICF_00296 7.1e-20 brnQ U Component of the transport system for branched-chain amino acids
HEJKOICF_00299 1e-19 L transposase, IS605 OrfB family
HEJKOICF_00300 4.7e-154 L COG2801 Transposase and inactivated derivatives
HEJKOICF_00301 1.3e-38 L Transposase and inactivated derivatives
HEJKOICF_00302 1.9e-46 L Transposase
HEJKOICF_00303 3.5e-129 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEJKOICF_00304 3.2e-24 S Protein of unknown function (DUF2813)
HEJKOICF_00305 1.9e-46 L Transposase
HEJKOICF_00306 8.8e-122 L transposase, IS605 OrfB family
HEJKOICF_00307 1.9e-46 L Transposase
HEJKOICF_00308 5e-122 L hmm pf00665
HEJKOICF_00309 1.9e-54 ydiI Q Thioesterase superfamily
HEJKOICF_00310 2.6e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEJKOICF_00311 4.4e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEJKOICF_00312 1.7e-218 G Transporter, major facilitator family protein
HEJKOICF_00313 1.6e-207 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HEJKOICF_00314 1.5e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEJKOICF_00315 1.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEJKOICF_00316 2.5e-40 gcvR T Belongs to the UPF0237 family
HEJKOICF_00317 6e-244 XK27_08635 S UPF0210 protein
HEJKOICF_00318 1.1e-178 yobV1 K WYL domain
HEJKOICF_00319 4.1e-68 S pyridoxamine 5-phosphate
HEJKOICF_00320 7.4e-35
HEJKOICF_00323 1.3e-63
HEJKOICF_00324 6.8e-114 yicL EG EamA-like transporter family
HEJKOICF_00325 2.6e-74 S Domain of unknown function (DUF4352)
HEJKOICF_00326 0.0 1.3.5.4 C FAD binding domain
HEJKOICF_00327 3.2e-77 K LysR substrate binding domain
HEJKOICF_00328 6.1e-52 K LysR substrate binding domain
HEJKOICF_00329 4.1e-161 rssA S Phospholipase, patatin family
HEJKOICF_00330 2.5e-214 phbA 2.3.1.9 I Belongs to the thiolase family
HEJKOICF_00331 5.6e-179 S AI-2E family transporter
HEJKOICF_00332 7.7e-124 S membrane transporter protein
HEJKOICF_00333 3.2e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HEJKOICF_00334 3.4e-194 V Beta-lactamase
HEJKOICF_00335 9.2e-228
HEJKOICF_00337 8.2e-154 S Alpha/beta hydrolase of unknown function (DUF915)
HEJKOICF_00338 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEJKOICF_00339 2.2e-165 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HEJKOICF_00340 1.2e-163 endA F DNA RNA non-specific endonuclease
HEJKOICF_00341 2.7e-268 pipD E Dipeptidase
HEJKOICF_00343 2.3e-254 yifK E Amino acid permease
HEJKOICF_00345 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEJKOICF_00346 1.7e-237 N Uncharacterized conserved protein (DUF2075)
HEJKOICF_00347 9.5e-43 S SNARE associated Golgi protein
HEJKOICF_00348 3.4e-79 ndk 2.7.4.6 F Belongs to the NDK family
HEJKOICF_00349 7e-98 padR K Virulence activator alpha C-term
HEJKOICF_00350 7.5e-32 L Transposase and inactivated derivatives IS30 family
HEJKOICF_00351 6e-44 L PFAM Integrase catalytic region
HEJKOICF_00352 2.9e-81 tlpA2 L Transposase IS200 like
HEJKOICF_00353 2.6e-31 L transposase, IS605 OrfB family
HEJKOICF_00354 1.5e-39 L Transposase
HEJKOICF_00355 8.7e-23 L Helix-turn-helix domain
HEJKOICF_00356 4.8e-190 L Helix-turn-helix domain
HEJKOICF_00357 6.2e-12 L Transposase
HEJKOICF_00358 6e-20 L transposase, IS605 OrfB family
HEJKOICF_00359 3e-148 L hmm pf00665
HEJKOICF_00360 8.8e-31 L Helix-turn-helix domain
HEJKOICF_00361 5.3e-79 mleR K LysR family
HEJKOICF_00362 4.2e-231 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HEJKOICF_00363 6.6e-182 XK27_09615 S reductase
HEJKOICF_00364 5.4e-91 XK27_09620 S NADPH-dependent FMN reductase
HEJKOICF_00365 6.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEJKOICF_00366 2.1e-215 frdC 1.3.5.4 C FAD binding domain
HEJKOICF_00367 1.9e-224 yflS P Sodium:sulfate symporter transmembrane region
HEJKOICF_00368 1e-162 mleR K LysR family transcriptional regulator
HEJKOICF_00369 1.6e-252 yjjP S Putative threonine/serine exporter
HEJKOICF_00370 2.1e-120 ung2 3.2.2.27 L Uracil-DNA glycosylase
HEJKOICF_00371 2.4e-189 I Alpha beta
HEJKOICF_00372 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HEJKOICF_00373 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEJKOICF_00375 2e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HEJKOICF_00376 8.5e-150 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HEJKOICF_00377 2.4e-114 S Domain of unknown function (DUF4811)
HEJKOICF_00378 6.6e-268 lmrB EGP Major facilitator Superfamily
HEJKOICF_00379 1.9e-74 merR K MerR HTH family regulatory protein
HEJKOICF_00380 2e-58
HEJKOICF_00381 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEJKOICF_00382 1.8e-215 S CAAX protease self-immunity
HEJKOICF_00383 8.1e-33 elaA S GNAT family
HEJKOICF_00384 1.7e-84 usp1 T Belongs to the universal stress protein A family
HEJKOICF_00385 3.8e-109 S VIT family
HEJKOICF_00386 7.2e-116 S membrane
HEJKOICF_00387 7.1e-164 czcD P cation diffusion facilitator family transporter
HEJKOICF_00388 4.5e-123 sirR K iron dependent repressor
HEJKOICF_00389 2.8e-28 cspA K Cold shock protein
HEJKOICF_00390 6.3e-126 thrE S Putative threonine/serine exporter
HEJKOICF_00391 2.8e-82 S Threonine/Serine exporter, ThrE
HEJKOICF_00392 9.1e-116 lssY 3.6.1.27 I phosphatase
HEJKOICF_00393 8.3e-156 I alpha/beta hydrolase fold
HEJKOICF_00395 3.9e-268 lysP E amino acid
HEJKOICF_00396 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HEJKOICF_00402 1.3e-61 L PFAM Integrase catalytic region
HEJKOICF_00403 3.7e-78 L Integrase core domain
HEJKOICF_00404 4e-22 tra L Transposase and inactivated derivatives, IS30 family
HEJKOICF_00405 1.5e-39 L Transposase
HEJKOICF_00406 4e-22 tra L Transposase and inactivated derivatives, IS30 family
HEJKOICF_00407 3.2e-23 L Helix-turn-helix domain
HEJKOICF_00408 3.5e-211 L transposase, IS605 OrfB family
HEJKOICF_00409 2.6e-184 S interspecies interaction between organisms
HEJKOICF_00410 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HEJKOICF_00411 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEJKOICF_00412 2.2e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEJKOICF_00413 1.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEJKOICF_00414 2e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEJKOICF_00415 1e-148 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEJKOICF_00416 2.8e-61 rplQ J Ribosomal protein L17
HEJKOICF_00417 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEJKOICF_00418 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEJKOICF_00419 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEJKOICF_00420 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HEJKOICF_00421 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEJKOICF_00422 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEJKOICF_00423 1e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEJKOICF_00424 2.1e-65 rplO J Binds to the 23S rRNA
HEJKOICF_00425 2.5e-23 rpmD J Ribosomal protein L30
HEJKOICF_00426 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEJKOICF_00427 5.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEJKOICF_00428 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEJKOICF_00429 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEJKOICF_00430 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEJKOICF_00431 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEJKOICF_00432 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEJKOICF_00433 3.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEJKOICF_00434 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEJKOICF_00435 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
HEJKOICF_00436 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEJKOICF_00437 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEJKOICF_00438 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEJKOICF_00439 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEJKOICF_00440 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEJKOICF_00441 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEJKOICF_00442 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
HEJKOICF_00443 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEJKOICF_00444 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HEJKOICF_00445 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEJKOICF_00446 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEJKOICF_00447 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEJKOICF_00448 2.1e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
HEJKOICF_00449 2.2e-213 ykiI
HEJKOICF_00450 5.6e-135 puuD S peptidase C26
HEJKOICF_00451 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEJKOICF_00452 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEJKOICF_00453 5.8e-106 K Bacterial regulatory proteins, tetR family
HEJKOICF_00454 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEJKOICF_00455 4.8e-79 ctsR K Belongs to the CtsR family
HEJKOICF_00456 9.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
HEJKOICF_00457 1.8e-98 tnp L MULE transposase domain
HEJKOICF_00458 1.4e-77 L Integrase core domain
HEJKOICF_00459 4.4e-49 tnp L MULE transposase domain
HEJKOICF_00460 7.1e-121 L transposase, IS605 OrfB family
HEJKOICF_00461 9.2e-21 L transposase, IS605 OrfB family
HEJKOICF_00462 2.7e-32 L Helix-turn-helix domain
HEJKOICF_00463 2.2e-30 E IrrE N-terminal-like domain
HEJKOICF_00464 4.8e-86 yrjD S LUD domain
HEJKOICF_00465 1.4e-244 lutB C 4Fe-4S dicluster domain
HEJKOICF_00466 5.6e-122 lutA C Cysteine-rich domain
HEJKOICF_00467 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HEJKOICF_00468 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEJKOICF_00469 2.4e-37 ynzC S UPF0291 protein
HEJKOICF_00470 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
HEJKOICF_00471 3.3e-115 plsC 2.3.1.51 I Acyltransferase
HEJKOICF_00472 8e-137 yabB 2.1.1.223 L Methyltransferase small domain
HEJKOICF_00473 2.3e-47 yazA L GIY-YIG catalytic domain protein
HEJKOICF_00474 5e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
HEJKOICF_00475 4.9e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEJKOICF_00476 1.6e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HEJKOICF_00477 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEJKOICF_00478 1.3e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEJKOICF_00479 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
HEJKOICF_00480 8.5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HEJKOICF_00481 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEJKOICF_00482 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEJKOICF_00483 1.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
HEJKOICF_00484 8e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HEJKOICF_00485 1.2e-206 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEJKOICF_00486 1.1e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEJKOICF_00487 2.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEJKOICF_00488 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HEJKOICF_00489 9.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HEJKOICF_00490 3.7e-224 nusA K Participates in both transcription termination and antitermination
HEJKOICF_00491 1.4e-47 ylxR K Protein of unknown function (DUF448)
HEJKOICF_00492 3.2e-50 ylxQ J ribosomal protein
HEJKOICF_00493 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEJKOICF_00494 3.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEJKOICF_00495 2e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEJKOICF_00496 1.6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HEJKOICF_00497 1.1e-248 EGP Major facilitator Superfamily
HEJKOICF_00498 1.8e-58 L Helix-turn-helix domain
HEJKOICF_00499 2.2e-122 L hmm pf00665
HEJKOICF_00500 9.1e-38 L Helix-turn-helix domain
HEJKOICF_00501 8.7e-38 L hmm pf00665
HEJKOICF_00502 1.3e-139 L COG2801 Transposase and inactivated derivatives
HEJKOICF_00503 7.5e-37 tra L Transposase and inactivated derivatives, IS30 family
HEJKOICF_00504 9.5e-19 tnp L MULE transposase domain
HEJKOICF_00507 6.8e-130 K response regulator
HEJKOICF_00508 0.0 vicK 2.7.13.3 T Histidine kinase
HEJKOICF_00509 6.7e-240 yycH S YycH protein
HEJKOICF_00510 9.4e-144 yycI S YycH protein
HEJKOICF_00511 3e-153 vicX 3.1.26.11 S domain protein
HEJKOICF_00512 3e-208 htrA 3.4.21.107 O serine protease
HEJKOICF_00513 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEJKOICF_00514 5.7e-71 K Transcriptional regulator
HEJKOICF_00515 3.2e-175 malR K Transcriptional regulator, LacI family
HEJKOICF_00516 3e-251 malT G Major Facilitator
HEJKOICF_00517 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HEJKOICF_00518 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HEJKOICF_00519 1.1e-110 ysdA CP transmembrane transport
HEJKOICF_00520 1.4e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEJKOICF_00521 1.4e-183 D Alpha beta
HEJKOICF_00522 4.1e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEJKOICF_00523 6.5e-218 patA 2.6.1.1 E Aminotransferase
HEJKOICF_00524 2.7e-35
HEJKOICF_00525 0.0 clpL O associated with various cellular activities
HEJKOICF_00526 1.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEJKOICF_00527 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HEJKOICF_00528 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HEJKOICF_00529 3.6e-148 yvgN C Aldo keto reductase
HEJKOICF_00530 1.1e-289 glpQ 3.1.4.46 C phosphodiesterase
HEJKOICF_00531 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
HEJKOICF_00532 6e-189 ybhR V ABC transporter
HEJKOICF_00533 1.9e-127 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HEJKOICF_00534 2.8e-42 K transcriptional regulator
HEJKOICF_00535 1.8e-107 tnp L MULE transposase domain
HEJKOICF_00536 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
HEJKOICF_00537 1.8e-78 K Winged helix DNA-binding domain
HEJKOICF_00538 0.0 lmrA V ABC transporter, ATP-binding protein
HEJKOICF_00539 0.0 yfiC V ABC transporter
HEJKOICF_00540 2.8e-193 ampC V Beta-lactamase
HEJKOICF_00541 6.4e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEJKOICF_00542 2.8e-48
HEJKOICF_00543 3.4e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HEJKOICF_00544 7.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HEJKOICF_00545 3.2e-109 tdk 2.7.1.21 F thymidine kinase
HEJKOICF_00546 4.2e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEJKOICF_00547 7.1e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEJKOICF_00548 3.4e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEJKOICF_00549 1.7e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEJKOICF_00550 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEJKOICF_00551 3.3e-187 yibE S overlaps another CDS with the same product name
HEJKOICF_00552 2.5e-125 yibF S overlaps another CDS with the same product name
HEJKOICF_00553 5.4e-218 pyrP F Permease
HEJKOICF_00554 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HEJKOICF_00555 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEJKOICF_00556 1.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEJKOICF_00557 7.4e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEJKOICF_00558 2.1e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEJKOICF_00559 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEJKOICF_00560 4.4e-253 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEJKOICF_00561 6.4e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HEJKOICF_00562 2.8e-29 S Protein of unknown function (DUF1146)
HEJKOICF_00563 1.2e-219 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HEJKOICF_00564 2.6e-183 mbl D Cell shape determining protein MreB Mrl
HEJKOICF_00565 7.9e-32 S Protein of unknown function (DUF2969)
HEJKOICF_00566 2.2e-221 rodA D Belongs to the SEDS family
HEJKOICF_00568 5.3e-181 S Protein of unknown function (DUF2785)
HEJKOICF_00569 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HEJKOICF_00570 3.5e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HEJKOICF_00571 6.8e-81 usp6 T universal stress protein
HEJKOICF_00573 2e-236 rarA L recombination factor protein RarA
HEJKOICF_00574 1.5e-85 yueI S Protein of unknown function (DUF1694)
HEJKOICF_00575 3.3e-76 4.4.1.5 E Glyoxalase
HEJKOICF_00576 9.5e-19 tnp L MULE transposase domain
HEJKOICF_00577 7e-43 L Helix-turn-helix domain
HEJKOICF_00578 1.5e-39 L Transposase
HEJKOICF_00579 4.1e-48 tra L Transposase and inactivated derivatives, IS30 family
HEJKOICF_00580 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
HEJKOICF_00583 2.8e-38
HEJKOICF_00588 2.6e-28 M CHAP domain
HEJKOICF_00590 8.2e-186 U type IV secretory pathway VirB4
HEJKOICF_00591 2.1e-22
HEJKOICF_00594 1.1e-49 srtA 3.4.22.70 M sortase family
HEJKOICF_00596 9.9e-67
HEJKOICF_00597 1.3e-222 U TraM recognition site of TraD and TraG
HEJKOICF_00601 3.6e-146 clpB O Belongs to the ClpA ClpB family
HEJKOICF_00604 1.2e-138 topA2 5.99.1.2 G Topoisomerase IA
HEJKOICF_00605 1.8e-55 L Protein of unknown function (DUF3991)
HEJKOICF_00606 7.6e-12 nrdH O COG0695 Glutaredoxin and related proteins
HEJKOICF_00611 3.5e-44 XK27_00515 D Glucan-binding protein C
HEJKOICF_00614 1.9e-46 L Transposase
HEJKOICF_00615 7.3e-46 L Transposase
HEJKOICF_00616 6.1e-111 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEJKOICF_00617 1.1e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEJKOICF_00618 9.6e-178 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEJKOICF_00619 4.5e-263 lysC 2.7.2.4 E Belongs to the aspartokinase family
HEJKOICF_00620 2.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEJKOICF_00621 8.6e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEJKOICF_00622 6.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEJKOICF_00623 6e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEJKOICF_00624 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEJKOICF_00625 1.7e-218 patA 2.6.1.1 E Aminotransferase
HEJKOICF_00626 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEJKOICF_00627 6.7e-227 ktrB P Potassium uptake protein
HEJKOICF_00628 2.8e-117 ktrA P domain protein
HEJKOICF_00629 1.2e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HEJKOICF_00630 4.5e-157 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEJKOICF_00631 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HEJKOICF_00633 0.0 dnaE 2.7.7.7 L DNA polymerase
HEJKOICF_00634 2.4e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HEJKOICF_00635 1.6e-168 cvfB S S1 domain
HEJKOICF_00636 8.2e-133 xerD D recombinase XerD
HEJKOICF_00637 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEJKOICF_00638 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEJKOICF_00639 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEJKOICF_00640 2.8e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEJKOICF_00641 1.4e-80 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEJKOICF_00642 1.3e-198 ypbB 5.1.3.1 S Helix-turn-helix domain
HEJKOICF_00643 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HEJKOICF_00644 9.7e-31 M Lysin motif
HEJKOICF_00645 2e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HEJKOICF_00646 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
HEJKOICF_00647 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HEJKOICF_00648 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEJKOICF_00649 1.8e-234 S Tetratricopeptide repeat protein
HEJKOICF_00650 1.8e-164 xerD L Phage integrase, N-terminal SAM-like domain
HEJKOICF_00651 1.1e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEJKOICF_00652 0.0 yfmR S ABC transporter, ATP-binding protein
HEJKOICF_00653 2.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEJKOICF_00654 4.3e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEJKOICF_00655 1.2e-109 hlyIII S protein, hemolysin III
HEJKOICF_00656 2.4e-153 DegV S EDD domain protein, DegV family
HEJKOICF_00657 1.5e-217 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
HEJKOICF_00658 3.2e-107 cat S Bacterial transferase hexapeptide (six repeats)
HEJKOICF_00659 1.1e-167 ypmR E lipolytic protein G-D-S-L family
HEJKOICF_00660 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HEJKOICF_00661 3.1e-36 yozE S Belongs to the UPF0346 family
HEJKOICF_00662 1.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEJKOICF_00663 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEJKOICF_00664 8.1e-165 dprA LU DNA protecting protein DprA
HEJKOICF_00665 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEJKOICF_00666 1.2e-154 D DNA integration
HEJKOICF_00667 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
HEJKOICF_00668 2.8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEJKOICF_00669 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEJKOICF_00670 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEJKOICF_00671 5.2e-95 S Protein of unknown function (DUF1440)
HEJKOICF_00672 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
HEJKOICF_00673 2.3e-71 yqkB S Belongs to the HesB IscA family
HEJKOICF_00674 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HEJKOICF_00675 2e-76 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HEJKOICF_00676 5.9e-82 yebR 1.8.4.14 T GAF domain-containing protein
HEJKOICF_00677 9.4e-245 U Belongs to the purine-cytosine permease (2.A.39) family
HEJKOICF_00678 2.6e-241 codA 3.5.4.1 F cytosine deaminase
HEJKOICF_00679 0.0 oppD EP Psort location Cytoplasmic, score
HEJKOICF_00681 2e-255 rarA L recombination factor protein RarA
HEJKOICF_00682 3.1e-119 S Protein of unknown function (DUF554)
HEJKOICF_00683 9.3e-245 yhjX P Major Facilitator Superfamily
HEJKOICF_00685 6.5e-18 lmrB EGP Major facilitator Superfamily
HEJKOICF_00686 2.6e-20 clcA P chloride
HEJKOICF_00687 1.4e-22 L PFAM Integrase catalytic region
HEJKOICF_00688 1e-15
HEJKOICF_00689 4.5e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEJKOICF_00690 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HEJKOICF_00691 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEJKOICF_00692 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEJKOICF_00693 1.5e-253 yifK E Amino acid permease
HEJKOICF_00694 6.4e-290 clcA P chloride
HEJKOICF_00695 4.5e-33 secG U Preprotein translocase
HEJKOICF_00696 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEJKOICF_00697 3.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HEJKOICF_00698 5.5e-109 yxjI
HEJKOICF_00699 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEJKOICF_00700 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HEJKOICF_00701 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HEJKOICF_00702 1.6e-88 K Acetyltransferase (GNAT) domain
HEJKOICF_00703 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
HEJKOICF_00704 5.7e-166 murB 1.3.1.98 M Cell wall formation
HEJKOICF_00705 3.9e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEJKOICF_00706 9.1e-116 ybbR S YbbR-like protein
HEJKOICF_00707 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEJKOICF_00708 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEJKOICF_00709 3.3e-52
HEJKOICF_00710 3.2e-211 oatA I Acyltransferase
HEJKOICF_00711 2.8e-151 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HEJKOICF_00712 2.4e-75 lytE M Lysin motif
HEJKOICF_00713 2.7e-159 MA20_14895 S Conserved hypothetical protein 698
HEJKOICF_00714 3.4e-166 K LysR substrate binding domain
HEJKOICF_00715 1.1e-130 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEJKOICF_00716 6.6e-148 yitS S EDD domain protein, DegV family
HEJKOICF_00717 6.5e-90 racA K Domain of unknown function (DUF1836)
HEJKOICF_00718 2.3e-181 yfeX P Peroxidase
HEJKOICF_00719 5.3e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HEJKOICF_00720 2.7e-122 manY G PTS system
HEJKOICF_00721 3e-170 manN G system, mannose fructose sorbose family IID component
HEJKOICF_00722 1.6e-57 S Domain of unknown function (DUF956)
HEJKOICF_00723 8e-108 tnp L MULE transposase domain
HEJKOICF_00724 8e-108 tnp L MULE transposase domain
HEJKOICF_00725 9.2e-21 L transposase, IS605 OrfB family
HEJKOICF_00726 2e-42 L Helix-turn-helix domain
HEJKOICF_00727 2.8e-44 L Transposase IS200 like
HEJKOICF_00728 3.2e-23 L Helix-turn-helix domain
HEJKOICF_00729 3e-41 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HEJKOICF_00730 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEJKOICF_00731 1.2e-163 S Tetratricopeptide repeat
HEJKOICF_00732 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEJKOICF_00733 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEJKOICF_00734 1.3e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEJKOICF_00735 2.8e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HEJKOICF_00736 4.1e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HEJKOICF_00738 3.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HEJKOICF_00739 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEJKOICF_00740 1.1e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEJKOICF_00741 8.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEJKOICF_00742 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEJKOICF_00743 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HEJKOICF_00744 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEJKOICF_00745 3.6e-61 S Domain of unknown function (DUF4440)
HEJKOICF_00746 8.6e-187 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEJKOICF_00747 1.1e-152 tesE Q hydratase
HEJKOICF_00748 2.9e-43 adhR K helix_turn_helix, mercury resistance
HEJKOICF_00749 8.9e-98 ywrO S Flavodoxin-like fold
HEJKOICF_00750 7.6e-21 S Protein conserved in bacteria
HEJKOICF_00751 3e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HEJKOICF_00752 6.2e-51 S Sugar efflux transporter for intercellular exchange
HEJKOICF_00753 5.9e-17 xre K Helix-turn-helix domain
HEJKOICF_00754 3.7e-199 gldA 1.1.1.6 C dehydrogenase
HEJKOICF_00755 2.3e-119 IQ Enoyl-(Acyl carrier protein) reductase
HEJKOICF_00756 1.5e-103 S Bacterial transferase hexapeptide (six repeats)
HEJKOICF_00758 3.1e-150 L PFAM Integrase catalytic region
HEJKOICF_00759 0.0 asnB 6.3.5.4 E Aluminium induced protein
HEJKOICF_00761 1.4e-12 S CHY zinc finger
HEJKOICF_00763 2.6e-10 M domain protein
HEJKOICF_00764 5e-52 L hmm pf00665
HEJKOICF_00765 9.5e-19 tnp L MULE transposase domain
HEJKOICF_00766 4e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
HEJKOICF_00767 5.4e-95 fhuC P ABC transporter
HEJKOICF_00768 3.2e-128 znuB U ABC 3 transport family
HEJKOICF_00769 2.2e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HEJKOICF_00770 7.3e-205 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEJKOICF_00771 3.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEJKOICF_00772 3e-32
HEJKOICF_00773 4.8e-143 yxeH S hydrolase
HEJKOICF_00774 1.5e-266 ywfO S HD domain protein
HEJKOICF_00775 3.2e-74 ywiB S Domain of unknown function (DUF1934)
HEJKOICF_00776 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEJKOICF_00777 4.4e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEJKOICF_00778 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEJKOICF_00779 6e-41 rpmE2 J Ribosomal protein L31
HEJKOICF_00780 1.6e-28 mdtG EGP Major facilitator Superfamily
HEJKOICF_00781 4.7e-123 srtA 3.4.22.70 M sortase family
HEJKOICF_00782 6.2e-47 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEJKOICF_00783 3.3e-87 lemA S LemA family
HEJKOICF_00784 4.9e-157 htpX O Belongs to the peptidase M48B family
HEJKOICF_00785 2.1e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEJKOICF_00786 1.9e-254 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEJKOICF_00787 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEJKOICF_00788 9.6e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEJKOICF_00789 1.9e-56 L Toxic component of a toxin-antitoxin (TA) module
HEJKOICF_00790 4e-113 S (CBS) domain
HEJKOICF_00791 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEJKOICF_00792 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEJKOICF_00793 1.6e-39 yabO J S4 domain protein
HEJKOICF_00794 1.5e-56 divIC D Septum formation initiator
HEJKOICF_00795 3e-87 yabR J RNA binding
HEJKOICF_00796 2.8e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEJKOICF_00797 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HEJKOICF_00798 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEJKOICF_00799 9.2e-23 L Helix-turn-helix domain
HEJKOICF_00800 3.6e-42 L Transposase
HEJKOICF_00801 5.8e-189 lacS G Transporter
HEJKOICF_00802 0.0 rafA 3.2.1.22 G alpha-galactosidase
HEJKOICF_00803 2.5e-178 galR K Transcriptional regulator
HEJKOICF_00804 3.1e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HEJKOICF_00805 2.1e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEJKOICF_00806 7.7e-185 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HEJKOICF_00807 1.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
HEJKOICF_00808 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
HEJKOICF_00809 2e-35
HEJKOICF_00810 6.6e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HEJKOICF_00811 5.3e-119 tcyB U Binding-protein-dependent transport system inner membrane component
HEJKOICF_00812 5.7e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HEJKOICF_00813 2e-52
HEJKOICF_00814 4e-170 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEJKOICF_00815 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEJKOICF_00816 6.9e-147 pnuC H nicotinamide mononucleotide transporter
HEJKOICF_00817 1.1e-92 ymdB S Macro domain protein
HEJKOICF_00818 0.0 pepO 3.4.24.71 O Peptidase family M13
HEJKOICF_00819 1.8e-229 pbuG S permease
HEJKOICF_00820 2.1e-45
HEJKOICF_00821 4.9e-213 S Putative metallopeptidase domain
HEJKOICF_00822 8e-205 3.1.3.1 S associated with various cellular activities
HEJKOICF_00823 1.3e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HEJKOICF_00824 6.8e-65 yeaO S Protein of unknown function, DUF488
HEJKOICF_00826 1.8e-124 yrkL S Flavodoxin-like fold
HEJKOICF_00827 3.3e-55
HEJKOICF_00828 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HEJKOICF_00829 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEJKOICF_00830 3.2e-102
HEJKOICF_00831 9.5e-26
HEJKOICF_00832 2.4e-170 scrR K Transcriptional regulator, LacI family
HEJKOICF_00833 2.7e-174 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEJKOICF_00834 2.6e-46 czrA K Transcriptional regulator, ArsR family
HEJKOICF_00835 1.1e-163 K AI-2E family transporter
HEJKOICF_00836 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HEJKOICF_00837 8.1e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEJKOICF_00838 2.6e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEJKOICF_00839 3.3e-255 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEJKOICF_00840 2.1e-172 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
HEJKOICF_00841 1.7e-245 S response to antibiotic
HEJKOICF_00842 2.3e-95 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
HEJKOICF_00843 2.1e-14 IQ Dehydrogenase
HEJKOICF_00844 1.4e-29 IQ Dehydrogenase
HEJKOICF_00847 6.5e-136 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HEJKOICF_00848 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEJKOICF_00849 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEJKOICF_00850 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEJKOICF_00851 5.7e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEJKOICF_00852 1.6e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HEJKOICF_00853 2.3e-107 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEJKOICF_00854 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HEJKOICF_00855 2.6e-241 purD 6.3.4.13 F Belongs to the GARS family
HEJKOICF_00856 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEJKOICF_00857 2.3e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HEJKOICF_00858 2.5e-178
HEJKOICF_00859 1.9e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HEJKOICF_00860 1.2e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HEJKOICF_00861 0.0 copA 3.6.3.54 P P-type ATPase
HEJKOICF_00862 4.9e-30 EGP Major facilitator Superfamily
HEJKOICF_00863 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
HEJKOICF_00864 2.4e-142 EG EamA-like transporter family
HEJKOICF_00865 4.3e-258 XK27_04775 S PAS domain
HEJKOICF_00866 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
HEJKOICF_00867 8e-54 yitW S Iron-sulfur cluster assembly protein
HEJKOICF_00868 2e-230 ndh 1.6.99.3 C NADH dehydrogenase
HEJKOICF_00869 2.2e-142 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HEJKOICF_00870 2.5e-170 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEJKOICF_00871 5.8e-58 S Flavodoxin
HEJKOICF_00872 2.2e-72 moaE 2.8.1.12 H MoaE protein
HEJKOICF_00873 6.4e-35 moaD 2.8.1.12 H ThiS family
HEJKOICF_00874 3.5e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEJKOICF_00875 3.6e-216 narK P Major Facilitator Superfamily
HEJKOICF_00876 9.7e-58 yitW S Iron-sulfur cluster assembly protein
HEJKOICF_00877 1e-162 hipB K Helix-turn-helix
HEJKOICF_00878 1e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEJKOICF_00880 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HEJKOICF_00881 8.8e-184
HEJKOICF_00882 1.2e-39
HEJKOICF_00883 4e-116 nreC K PFAM regulatory protein LuxR
HEJKOICF_00884 3.6e-183 comP 2.7.13.3 F Sensor histidine kinase
HEJKOICF_00885 1.4e-77 nreA T GAF domain
HEJKOICF_00886 4.2e-40
HEJKOICF_00887 1.8e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEJKOICF_00888 9.3e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEJKOICF_00889 1.2e-230 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HEJKOICF_00890 5.6e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HEJKOICF_00891 1.2e-188 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HEJKOICF_00892 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEJKOICF_00893 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
HEJKOICF_00894 3.1e-102 narJ C Nitrate reductase delta subunit
HEJKOICF_00895 4e-127 narI 1.7.5.1 C Nitrate reductase
HEJKOICF_00896 8.4e-81 tlpA2 L Transposase IS200 like
HEJKOICF_00897 3.8e-28 L Helix-turn-helix domain
HEJKOICF_00898 1.9e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HEJKOICF_00899 4.6e-23 D mRNA cleavage
HEJKOICF_00900 1.4e-185 S Phosphotransferase system, EIIC
HEJKOICF_00901 2e-194 nhaC C Na H antiporter NhaC
HEJKOICF_00903 3.1e-75 ddaH 3.5.3.18 E Amidinotransferase
HEJKOICF_00904 5.4e-89 S Aminoacyl-tRNA editing domain
HEJKOICF_00905 0.0 mco Q Multicopper oxidase
HEJKOICF_00906 2.8e-51 K 2 iron, 2 sulfur cluster binding
HEJKOICF_00907 8.6e-91 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HEJKOICF_00908 1.2e-118 Q Methyltransferase domain
HEJKOICF_00910 1.6e-100 S CAAX protease self-immunity
HEJKOICF_00911 2.3e-98 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEJKOICF_00912 2.8e-47 fsr EGP Major Facilitator Superfamily
HEJKOICF_00913 8.6e-64 fsr EGP Major Facilitator Superfamily
HEJKOICF_00914 1.4e-101 K helix_turn_helix multiple antibiotic resistance protein
HEJKOICF_00915 1.3e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HEJKOICF_00916 1.6e-105
HEJKOICF_00917 2e-85 dps P Belongs to the Dps family
HEJKOICF_00918 1.3e-304 ybiT S ABC transporter, ATP-binding protein
HEJKOICF_00919 2.3e-33 yneR S Belongs to the HesB IscA family
HEJKOICF_00920 3.6e-140 S NADPH-dependent FMN reductase
HEJKOICF_00921 6.2e-290 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HEJKOICF_00922 1.1e-159 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HEJKOICF_00923 1.4e-104 yvdD 3.2.2.10 S Belongs to the LOG family
HEJKOICF_00924 4.9e-63 S Domain of unknown function (DUF4828)
HEJKOICF_00925 1.3e-190 mocA S Oxidoreductase
HEJKOICF_00926 8.9e-232 yfmL 3.6.4.13 L DEAD DEAH box helicase
HEJKOICF_00928 3e-75 gtcA S Teichoic acid glycosylation protein
HEJKOICF_00929 8.5e-78 fld C Flavodoxin
HEJKOICF_00930 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
HEJKOICF_00931 2.1e-77 XK27_08315 M Sulfatase
HEJKOICF_00932 1.1e-19 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEJKOICF_00933 5.1e-66 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HEJKOICF_00934 1.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEJKOICF_00935 5.6e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HEJKOICF_00936 2.4e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HEJKOICF_00937 2.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HEJKOICF_00938 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HEJKOICF_00939 1.6e-88 ypmB S Protein conserved in bacteria
HEJKOICF_00940 2.1e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HEJKOICF_00941 4.7e-134 dnaD L DnaD domain protein
HEJKOICF_00942 1.3e-121 ypuA S Protein of unknown function (DUF1002)
HEJKOICF_00943 1.8e-192 C Aldo keto reductase family protein
HEJKOICF_00944 3.7e-160 EG EamA-like transporter family
HEJKOICF_00945 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HEJKOICF_00946 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEJKOICF_00947 1.3e-110 ypsA S Belongs to the UPF0398 family
HEJKOICF_00948 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEJKOICF_00949 0.0 tetP J elongation factor G
HEJKOICF_00950 6.8e-212 S Type IV secretion-system coupling protein DNA-binding domain
HEJKOICF_00951 8.9e-83 F Hydrolase, NUDIX family
HEJKOICF_00952 8.5e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HEJKOICF_00953 2.6e-15 arcD S C4-dicarboxylate anaerobic carrier
HEJKOICF_00954 9.8e-104 arcD S C4-dicarboxylate anaerobic carrier
HEJKOICF_00955 1.2e-272 nylA 3.5.1.4 J Belongs to the amidase family
HEJKOICF_00957 1.8e-77 L Integrase core domain
HEJKOICF_00958 0.0 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HEJKOICF_00959 6.3e-16 2.1.1.303 K DNA-binding transcription factor activity
HEJKOICF_00960 5.3e-300 L Recombinase
HEJKOICF_00961 0.0 L Recombinase zinc beta ribbon domain
HEJKOICF_00962 8e-35
HEJKOICF_00963 5.5e-145 M Glycosyl hydrolases family 25
HEJKOICF_00964 3.6e-70 S Bacteriophage holin family
HEJKOICF_00965 6.9e-68 S Phage head-tail joining protein
HEJKOICF_00966 2.8e-42 S Phage gp6-like head-tail connector protein
HEJKOICF_00967 9.7e-222 S Phage capsid family
HEJKOICF_00968 1.4e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HEJKOICF_00969 2.2e-243 S Phage portal protein
HEJKOICF_00970 4e-303 S overlaps another CDS with the same product name
HEJKOICF_00971 6.8e-30 S Domain of unknown function (DUF5049)
HEJKOICF_00972 7.2e-99 S Psort location Cytoplasmic, score
HEJKOICF_00973 8.8e-234 2.1.1.72 KL DNA methylase
HEJKOICF_00974 2.4e-71
HEJKOICF_00975 8.9e-86
HEJKOICF_00976 5e-254 L SNF2 family N-terminal domain
HEJKOICF_00977 8.4e-47 S VRR_NUC
HEJKOICF_00978 0.0 S Phage plasmid primase, P4
HEJKOICF_00979 2.8e-69 S Psort location Cytoplasmic, score
HEJKOICF_00980 0.0 polA_2 2.7.7.7 L DNA polymerase
HEJKOICF_00981 2.7e-97 S Protein of unknown function (DUF2815)
HEJKOICF_00982 1.2e-208 L Protein of unknown function (DUF2800)
HEJKOICF_00983 2.2e-40
HEJKOICF_00984 1e-22
HEJKOICF_00985 1e-70 K DNA-templated transcription, initiation
HEJKOICF_00986 1.4e-19 S Domain of unknown function (DUF1837)
HEJKOICF_00987 3.7e-116 L Dead deah box helicase domain protein
HEJKOICF_00988 1.5e-222 4.4.1.8 E Aminotransferase, class I
HEJKOICF_00989 3.2e-180 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEJKOICF_00990 3.2e-203 xerS L Belongs to the 'phage' integrase family
HEJKOICF_00991 1.2e-61 ywkB S Membrane transport protein
HEJKOICF_00992 9.6e-236 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
HEJKOICF_00993 1.4e-150 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HEJKOICF_00994 2.6e-80 hmpT S ECF-type riboflavin transporter, S component
HEJKOICF_00995 5.1e-167 1.1.1.346 C Aldo keto reductase
HEJKOICF_00996 2.4e-159 S DUF218 domain
HEJKOICF_00998 1.3e-96 K Acetyltransferase (GNAT) domain
HEJKOICF_00999 1.1e-163 I alpha/beta hydrolase fold
HEJKOICF_01000 2.6e-118 S Phage minor capsid protein 2
HEJKOICF_01003 1.3e-215 2.6.1.1 E Aminotransferase
HEJKOICF_01004 1.7e-123 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HEJKOICF_01005 1.7e-33 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HEJKOICF_01006 7.8e-247 EGP Sugar (and other) transporter
HEJKOICF_01007 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HEJKOICF_01008 2.8e-74 S Fic/DOC family
HEJKOICF_01009 8.9e-72 yncA 2.3.1.79 S Maltose acetyltransferase
HEJKOICF_01010 1.4e-105 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HEJKOICF_01011 4.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HEJKOICF_01012 1.7e-260 arcD E Amino acid permease
HEJKOICF_01013 8.5e-118 5.1.1.13 M racemase activity, acting on amino acids and derivatives
HEJKOICF_01014 6e-158 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
HEJKOICF_01015 1.7e-29 clcA P chloride
HEJKOICF_01016 3.1e-37 clcA P chloride
HEJKOICF_01017 5.3e-192 L Transposase and inactivated derivatives, IS30 family
HEJKOICF_01018 3.6e-46 tlpA2 L Transposase IS200 like
HEJKOICF_01019 2.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEJKOICF_01020 7.1e-217 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
HEJKOICF_01021 5e-70 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEJKOICF_01022 5.8e-197 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HEJKOICF_01023 3.3e-214 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEJKOICF_01024 1.3e-12 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
HEJKOICF_01025 2.4e-212 ydiN G Major Facilitator Superfamily
HEJKOICF_01027 9e-241 dtpT U amino acid peptide transporter
HEJKOICF_01030 2.5e-152 S Sucrose-6F-phosphate phosphohydrolase
HEJKOICF_01031 3.9e-119 1.6.5.2 GM NAD(P)H-binding
HEJKOICF_01032 1.6e-157 S Alpha beta hydrolase
HEJKOICF_01033 2.7e-237 lmrB EGP Major facilitator Superfamily
HEJKOICF_01035 0.0 S Bacterial membrane protein YfhO
HEJKOICF_01036 1.4e-50
HEJKOICF_01037 0.0 kup P Transport of potassium into the cell
HEJKOICF_01039 3.9e-284 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEJKOICF_01040 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HEJKOICF_01041 0.0 yjbQ P TrkA C-terminal domain protein
HEJKOICF_01042 1.1e-275 pipD E Dipeptidase
HEJKOICF_01043 1.7e-157 S Alpha/beta hydrolase of unknown function (DUF915)
HEJKOICF_01044 8.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEJKOICF_01045 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEJKOICF_01046 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
HEJKOICF_01047 2.1e-159 EGP Major facilitator Superfamily
HEJKOICF_01048 7.5e-201 mdtG EGP Major facilitator Superfamily
HEJKOICF_01049 1.3e-249 yhdP S Transporter associated domain
HEJKOICF_01050 1.7e-213 naiP EGP Major facilitator Superfamily
HEJKOICF_01051 1.7e-15 K LysR substrate binding domain protein
HEJKOICF_01052 7.2e-52 K Transcriptional regulator
HEJKOICF_01053 2.2e-215 E GDSL-like Lipase/Acylhydrolase family
HEJKOICF_01054 2.3e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HEJKOICF_01055 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
HEJKOICF_01056 1.5e-204 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEJKOICF_01057 1.3e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HEJKOICF_01058 1.8e-182 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HEJKOICF_01059 7.3e-55 yphJ 4.1.1.44 S decarboxylase
HEJKOICF_01060 2.8e-54 azlD E Branched-chain amino acid transport
HEJKOICF_01061 2.8e-123 azlC E azaleucine resistance protein AzlC
HEJKOICF_01062 1.9e-286 thrC 4.2.3.1 E Threonine synthase
HEJKOICF_01063 3.5e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HEJKOICF_01064 2.3e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEJKOICF_01065 3.5e-99 K Acetyltransferase (GNAT) domain
HEJKOICF_01066 1.2e-112 ylbE GM NAD(P)H-binding
HEJKOICF_01067 3.3e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HEJKOICF_01068 2.4e-126 S Belongs to the UPF0246 family
HEJKOICF_01069 1.9e-96
HEJKOICF_01070 3.2e-161 degV S EDD domain protein, DegV family
HEJKOICF_01071 0.0 FbpA K Fibronectin-binding protein
HEJKOICF_01072 2.1e-100 P nitric oxide dioxygenase activity
HEJKOICF_01073 1.5e-49 C Flavodoxin
HEJKOICF_01074 3.4e-44 S Bacterial transferase hexapeptide (six repeats)
HEJKOICF_01075 2.9e-49 akr5f 1.1.1.346 S reductase
HEJKOICF_01076 4e-10 akr5f S reductase
HEJKOICF_01077 5.4e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HEJKOICF_01078 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HEJKOICF_01079 1.8e-206 carA 6.3.5.5 F Belongs to the CarA family
HEJKOICF_01080 2.6e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEJKOICF_01081 3e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEJKOICF_01082 1.7e-70 esbA S Family of unknown function (DUF5322)
HEJKOICF_01083 3.1e-71 rnhA 3.1.26.4 L Ribonuclease HI
HEJKOICF_01084 5.7e-109 XK27_02070 S Nitroreductase family
HEJKOICF_01085 3.6e-157 yckB ET Belongs to the bacterial solute-binding protein 3 family
HEJKOICF_01086 1.2e-118 yecS E ABC transporter permease
HEJKOICF_01087 8.4e-22 M Glycosyltransferase like family 2
HEJKOICF_01088 1.9e-46 L Transposase
HEJKOICF_01089 3.3e-29 L Transposase
HEJKOICF_01090 3.1e-124 S Membrane
HEJKOICF_01091 3.2e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEJKOICF_01092 0.0 pepF E oligoendopeptidase F
HEJKOICF_01093 1.7e-179 K helix_turn _helix lactose operon repressor
HEJKOICF_01094 6.7e-139 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEJKOICF_01095 1.9e-77 K AsnC family
HEJKOICF_01096 1.4e-81 uspA T universal stress protein
HEJKOICF_01097 9.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEJKOICF_01098 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEJKOICF_01099 2.3e-207 yeaN P Transporter, major facilitator family protein
HEJKOICF_01100 4.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
HEJKOICF_01101 2.4e-83 nrdI F Belongs to the NrdI family
HEJKOICF_01102 3.6e-252 yhdP S Transporter associated domain
HEJKOICF_01103 5.2e-90 GM epimerase
HEJKOICF_01104 5.8e-86 M1-874 K Domain of unknown function (DUF1836)
HEJKOICF_01105 2.9e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HEJKOICF_01106 1.6e-266 pipD E Dipeptidase
HEJKOICF_01107 3.2e-130
HEJKOICF_01108 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEJKOICF_01109 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
HEJKOICF_01110 1.1e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HEJKOICF_01111 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HEJKOICF_01112 5.4e-62
HEJKOICF_01113 7.1e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEJKOICF_01114 2.2e-57 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEJKOICF_01115 0.0 dnaK O Heat shock 70 kDa protein
HEJKOICF_01116 1.1e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEJKOICF_01117 2.8e-54 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEJKOICF_01118 1.6e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEJKOICF_01119 5.5e-96 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEJKOICF_01120 8.5e-56 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HEJKOICF_01121 1.4e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HEJKOICF_01122 5.1e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEJKOICF_01123 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEJKOICF_01124 3.3e-09
HEJKOICF_01125 1.9e-112 3.1.3.73 G phosphoglycerate mutase
HEJKOICF_01126 3.2e-112 C aldo keto reductase
HEJKOICF_01127 9.2e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEJKOICF_01128 3.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEJKOICF_01129 7.1e-269 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HEJKOICF_01130 7.9e-79 K 2 iron, 2 sulfur cluster binding
HEJKOICF_01131 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEJKOICF_01132 1.2e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HEJKOICF_01133 9.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HEJKOICF_01134 9.1e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEJKOICF_01135 7.2e-54 C FMN binding
HEJKOICF_01136 1.6e-63 T His Kinase A (phosphoacceptor) domain
HEJKOICF_01137 4.6e-52 T Transcriptional regulatory protein, C terminal
HEJKOICF_01138 4.7e-28 S ABC-type transport system involved in multi-copper enzyme maturation permease component
HEJKOICF_01139 1.2e-20 U Preprotein translocase subunit SecB
HEJKOICF_01143 2.5e-50 ruvB 3.6.4.12 L four-way junction helicase activity
HEJKOICF_01144 1.6e-37 sigA K Sigma-70 factor, region 1.2
HEJKOICF_01147 3.1e-79 endA F DNA RNA non-specific endonuclease
HEJKOICF_01155 1.4e-08
HEJKOICF_01157 2.7e-17 1.20.4.1 P ArsC family
HEJKOICF_01166 1.5e-17
HEJKOICF_01169 8.5e-11 S Protein conserved in bacteria
HEJKOICF_01171 2.1e-11 3.4.21.88 K Peptidase S24-like
HEJKOICF_01172 6e-10 E Zn peptidase
HEJKOICF_01173 1.5e-91 L Belongs to the 'phage' integrase family
HEJKOICF_01176 2.1e-90
HEJKOICF_01177 1.3e-78 F Nucleoside 2-deoxyribosyltransferase
HEJKOICF_01178 9.7e-183 scrR3 K Transcriptional regulator, LacI family
HEJKOICF_01179 3e-14
HEJKOICF_01180 6.6e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HEJKOICF_01181 1.4e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEJKOICF_01182 2e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEJKOICF_01183 0.0 asnB 6.3.5.4 E Asparagine synthase
HEJKOICF_01184 6.6e-220 lysP E amino acid
HEJKOICF_01185 7e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEJKOICF_01186 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEJKOICF_01187 2.5e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEJKOICF_01188 2.4e-145 jag S R3H domain protein
HEJKOICF_01189 7.5e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEJKOICF_01190 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEJKOICF_01191 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HEJKOICF_01193 1.4e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEJKOICF_01194 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEJKOICF_01195 2.2e-34 yaaA S S4 domain protein YaaA
HEJKOICF_01196 5.6e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEJKOICF_01197 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEJKOICF_01198 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEJKOICF_01199 1.3e-100 P Cadmium resistance transporter
HEJKOICF_01200 3.2e-116 S Protein of unknown function (DUF554)
HEJKOICF_01201 8.4e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEJKOICF_01202 2.3e-156 P Belongs to the nlpA lipoprotein family
HEJKOICF_01203 3.9e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEJKOICF_01204 2.5e-37 V CAAX protease self-immunity
HEJKOICF_01205 1.7e-67 psiE S Phosphate-starvation-inducible E
HEJKOICF_01206 1.5e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HEJKOICF_01207 3.5e-109 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEJKOICF_01208 7.2e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HEJKOICF_01209 2.5e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEJKOICF_01210 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEJKOICF_01211 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HEJKOICF_01212 1.9e-92 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEJKOICF_01213 3.2e-34 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEJKOICF_01214 1.1e-36 S CRISPR-associated protein (Cas_Csn2)
HEJKOICF_01216 7.3e-34 aes I Hydrolase, alpha beta domain protein
HEJKOICF_01217 2.5e-56 L hmm pf00665
HEJKOICF_01218 1.8e-36 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HEJKOICF_01219 2.4e-216 G PTS system sugar-specific permease component
HEJKOICF_01220 3.8e-57 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEJKOICF_01221 1.7e-11 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HEJKOICF_01222 7.5e-155 manR K PRD domain
HEJKOICF_01223 1.2e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HEJKOICF_01224 0.0 L Helicase C-terminal domain protein
HEJKOICF_01225 1.6e-54 S MazG-like family
HEJKOICF_01226 1.8e-107 lssY 3.6.1.27 I Acid phosphatase homologues
HEJKOICF_01227 2.9e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HEJKOICF_01228 7.7e-97
HEJKOICF_01229 5.8e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HEJKOICF_01230 1.3e-168 ponA V Beta-lactamase enzyme family
HEJKOICF_01231 6.2e-266 yjeM E Amino Acid
HEJKOICF_01233 5.5e-112
HEJKOICF_01234 2e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HEJKOICF_01235 3.2e-164 K LysR substrate binding domain
HEJKOICF_01236 5.6e-183
HEJKOICF_01237 5.9e-76
HEJKOICF_01238 7.2e-66 yjcE P Sodium proton antiporter
HEJKOICF_01239 3.5e-48 ywnB S NAD(P)H-binding
HEJKOICF_01240 6.9e-289 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HEJKOICF_01241 2.2e-96 V VanZ like family
HEJKOICF_01242 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HEJKOICF_01243 2.5e-61 yneR
HEJKOICF_01244 1.4e-181 K Transcriptional regulator, LacI family
HEJKOICF_01245 9.4e-229 gntT EG Gluconate
HEJKOICF_01246 7.2e-286 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HEJKOICF_01247 6.2e-171 mutR K Transcriptional activator, Rgg GadR MutR family
HEJKOICF_01248 3.6e-08 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HEJKOICF_01249 1.6e-76 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HEJKOICF_01250 2.4e-192 yegU O ADP-ribosylglycohydrolase
HEJKOICF_01251 2.3e-251 F Belongs to the purine-cytosine permease (2.A.39) family
HEJKOICF_01252 7.2e-169 G Belongs to the carbohydrate kinase PfkB family
HEJKOICF_01253 1.3e-87 brnQ U Component of the transport system for branched-chain amino acids
HEJKOICF_01254 8.9e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEJKOICF_01255 3.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HEJKOICF_01256 1.2e-97 metI P ABC transporter permease
HEJKOICF_01257 8e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEJKOICF_01258 2.7e-149 metQ1 P Belongs to the nlpA lipoprotein family
HEJKOICF_01259 1.5e-259 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HEJKOICF_01260 3.2e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HEJKOICF_01261 6.9e-47
HEJKOICF_01262 1.8e-21 gntT EG gluconate transmembrane transporter activity
HEJKOICF_01263 1.1e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEJKOICF_01264 2.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEJKOICF_01265 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEJKOICF_01266 3.7e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HEJKOICF_01267 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEJKOICF_01268 7.4e-167 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEJKOICF_01269 3.8e-38 K transcriptional regulator
HEJKOICF_01270 8.3e-57 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEJKOICF_01271 1.7e-58 M repeat protein
HEJKOICF_01272 2.1e-09
HEJKOICF_01273 1.3e-168 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HEJKOICF_01274 1.6e-149 yueF S AI-2E family transporter
HEJKOICF_01275 3e-176 ykoT GT2 M Glycosyl transferase family 2
HEJKOICF_01276 0.0
HEJKOICF_01277 1.4e-178 rfbJ M Glycosyl transferase family 2
HEJKOICF_01278 1.3e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HEJKOICF_01279 1.9e-308 S Psort location CytoplasmicMembrane, score
HEJKOICF_01280 2.2e-179 cps3B S Glycosyltransferase like family 2
HEJKOICF_01281 1.8e-170 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEJKOICF_01282 7.8e-64 gntR1 K Transcriptional regulator, GntR family
HEJKOICF_01283 3.6e-157 V ABC transporter, ATP-binding protein
HEJKOICF_01284 3.6e-14
HEJKOICF_01285 2.8e-38 ykuJ S Protein of unknown function (DUF1797)
HEJKOICF_01286 6.5e-182 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEJKOICF_01287 1.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
HEJKOICF_01288 1.3e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HEJKOICF_01289 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEJKOICF_01290 4.7e-39 ptsH G phosphocarrier protein HPR
HEJKOICF_01292 0.0 clpE O Belongs to the ClpA ClpB family
HEJKOICF_01293 4.9e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
HEJKOICF_01294 6.4e-110 pncA Q Isochorismatase family
HEJKOICF_01295 2e-266 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEJKOICF_01296 1.7e-97 S Pfam:DUF3816
HEJKOICF_01297 3.6e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HEJKOICF_01298 2.1e-135 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEJKOICF_01299 1.9e-161 EG EamA-like transporter family
HEJKOICF_01300 1.2e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
HEJKOICF_01302 6.7e-47 L hmm pf00665
HEJKOICF_01305 4.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEJKOICF_01306 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEJKOICF_01307 1e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HEJKOICF_01308 2.5e-115 radC L DNA repair protein
HEJKOICF_01309 1.9e-181 mreB D cell shape determining protein MreB
HEJKOICF_01310 3.7e-146 mreC M Involved in formation and maintenance of cell shape
HEJKOICF_01311 1.9e-92 mreD M rod shape-determining protein MreD
HEJKOICF_01312 1.4e-108 glnP P ABC transporter permease
HEJKOICF_01313 7.4e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HEJKOICF_01314 7e-161 aatB ET ABC transporter substrate-binding protein
HEJKOICF_01315 4.3e-231 ymfF S Peptidase M16 inactive domain protein
HEJKOICF_01316 2.2e-251 ymfH S Peptidase M16
HEJKOICF_01317 1.8e-96 ymfM S Helix-turn-helix domain
HEJKOICF_01318 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEJKOICF_01319 1.9e-231 cinA 3.5.1.42 S Belongs to the CinA family
HEJKOICF_01320 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEJKOICF_01321 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
HEJKOICF_01322 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEJKOICF_01323 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEJKOICF_01324 1.1e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEJKOICF_01325 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEJKOICF_01326 7.5e-177 2.4.2.29 F queuine tRNA-ribosyltransferase activity
HEJKOICF_01327 5.5e-42 yajC U Preprotein translocase
HEJKOICF_01328 6.8e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HEJKOICF_01329 8.4e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEJKOICF_01330 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEJKOICF_01331 1.2e-42 yrzL S Belongs to the UPF0297 family
HEJKOICF_01332 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEJKOICF_01333 5.7e-33 yrzB S Belongs to the UPF0473 family
HEJKOICF_01334 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEJKOICF_01335 4.7e-91 cvpA S Colicin V production protein
HEJKOICF_01336 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEJKOICF_01337 1e-53 trxA O Belongs to the thioredoxin family
HEJKOICF_01338 1.2e-225 clcA_2 P Chloride transporter, ClC family
HEJKOICF_01339 3e-93 yslB S Protein of unknown function (DUF2507)
HEJKOICF_01340 1.8e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HEJKOICF_01341 3.6e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEJKOICF_01342 1.4e-95 S Phosphoesterase
HEJKOICF_01343 1.7e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HEJKOICF_01344 2e-155 ykuT M mechanosensitive ion channel
HEJKOICF_01345 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEJKOICF_01346 4.9e-70
HEJKOICF_01347 4.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HEJKOICF_01348 2.2e-185 ccpA K catabolite control protein A
HEJKOICF_01349 3.6e-85
HEJKOICF_01350 3.7e-134 yebC K Transcriptional regulatory protein
HEJKOICF_01351 3.2e-83 mltD CBM50 M PFAM NLP P60 protein
HEJKOICF_01352 7.5e-240 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HEJKOICF_01353 2.7e-61 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HEJKOICF_01354 2.7e-177 comGA NU Type II IV secretion system protein
HEJKOICF_01355 1.6e-159 comGB NU type II secretion system
HEJKOICF_01356 1.1e-47 comGC U competence protein ComGC
HEJKOICF_01357 2.3e-15 NU general secretion pathway protein
HEJKOICF_01359 1e-14
HEJKOICF_01361 8.6e-159 ytxK 2.1.1.72 L N-6 DNA Methylase
HEJKOICF_01362 9.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEJKOICF_01363 5.3e-110 S Calcineurin-like phosphoesterase
HEJKOICF_01364 1.2e-97 yutD S Protein of unknown function (DUF1027)
HEJKOICF_01365 6.6e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEJKOICF_01366 5.7e-25 S Protein of unknown function (DUF1461)
HEJKOICF_01367 2.9e-103 dedA S SNARE-like domain protein
HEJKOICF_01368 7.1e-167 whiA K May be required for sporulation
HEJKOICF_01369 1.7e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HEJKOICF_01370 2.1e-160 rapZ S Displays ATPase and GTPase activities
HEJKOICF_01371 2.2e-204
HEJKOICF_01372 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEJKOICF_01373 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEJKOICF_01375 1.4e-113 yfbR S HD containing hydrolase-like enzyme
HEJKOICF_01376 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEJKOICF_01377 2.8e-137 cof S haloacid dehalogenase-like hydrolase
HEJKOICF_01378 3.7e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HEJKOICF_01379 1.5e-197 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HEJKOICF_01380 5.2e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEJKOICF_01381 1.3e-153 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HEJKOICF_01382 9.7e-132 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEJKOICF_01383 1.4e-33 L PFAM Integrase catalytic region
HEJKOICF_01384 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HEJKOICF_01385 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
HEJKOICF_01386 3.9e-221 G Major Facilitator
HEJKOICF_01387 0.0 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HEJKOICF_01388 2.3e-84 3.2.1.37 GH43 K helix_turn_helix, arabinose operon control protein
HEJKOICF_01389 1.8e-297 xylB 2.7.1.12, 2.7.1.17 G Xylulose kinase
HEJKOICF_01390 6.4e-270 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HEJKOICF_01391 1.6e-252 xylT EGP Major facilitator Superfamily
HEJKOICF_01392 3.5e-216 xylR GK ROK family
HEJKOICF_01393 1.7e-151 glcU U sugar transport
HEJKOICF_01394 9.7e-251 yclK 2.7.13.3 T Histidine kinase
HEJKOICF_01395 9.7e-132 K response regulator
HEJKOICF_01398 3.7e-282 yjeM E Amino Acid
HEJKOICF_01399 1.7e-187 K helix_turn _helix lactose operon repressor
HEJKOICF_01400 9.8e-261 G PTS system Galactitol-specific IIC component
HEJKOICF_01401 2.7e-174 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEJKOICF_01402 6.9e-200 S Domain of unknown function (DUF4432)
HEJKOICF_01403 9.8e-115 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEJKOICF_01404 3.7e-171 deoR K sugar-binding domain protein
HEJKOICF_01405 2.2e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEJKOICF_01406 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEJKOICF_01407 2.7e-244 fucP G Major Facilitator Superfamily
HEJKOICF_01408 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEJKOICF_01409 7e-43 L Helix-turn-helix domain
HEJKOICF_01411 1.4e-133 XK27_08845 S ABC transporter, ATP-binding protein
HEJKOICF_01412 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HEJKOICF_01413 7e-181 ABC-SBP S ABC transporter
HEJKOICF_01414 3.4e-291 S ABC transporter, ATP-binding protein
HEJKOICF_01415 2e-205 nrnB S DHHA1 domain
HEJKOICF_01417 5.1e-110 M ErfK YbiS YcfS YnhG
HEJKOICF_01418 1.4e-83 nrdI F NrdI Flavodoxin like
HEJKOICF_01419 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEJKOICF_01420 2.6e-169 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
HEJKOICF_01421 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
HEJKOICF_01422 2.5e-274 S Uncharacterized protein conserved in bacteria (DUF2325)
HEJKOICF_01423 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HEJKOICF_01424 3.2e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEJKOICF_01425 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEJKOICF_01426 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HEJKOICF_01427 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEJKOICF_01428 2.8e-162 camS S sex pheromone
HEJKOICF_01429 1.5e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEJKOICF_01430 6.3e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEJKOICF_01431 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEJKOICF_01432 5.7e-186 yegS 2.7.1.107 G Lipid kinase
HEJKOICF_01433 4.1e-264 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEJKOICF_01434 1.3e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEJKOICF_01435 9.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEJKOICF_01436 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEJKOICF_01437 9e-147 tatD L hydrolase, TatD family
HEJKOICF_01438 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEJKOICF_01439 4e-161 yunF F Protein of unknown function DUF72
HEJKOICF_01440 5.3e-212 norA EGP Major facilitator Superfamily
HEJKOICF_01441 4.8e-128 cobB K SIR2 family
HEJKOICF_01442 2.2e-187
HEJKOICF_01443 6.2e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HEJKOICF_01444 6.6e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HEJKOICF_01445 0.0 helD 3.6.4.12 L DNA helicase
HEJKOICF_01446 2.7e-91 K Transcriptional regulator, TetR family
HEJKOICF_01447 1.1e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HEJKOICF_01448 6.2e-85 ykhA 3.1.2.20 I Thioesterase superfamily
HEJKOICF_01449 4.7e-66 lytE M LysM domain protein
HEJKOICF_01450 5.7e-197 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HEJKOICF_01451 4.6e-236 F Permease
HEJKOICF_01452 5.4e-161 sufD O Uncharacterized protein family (UPF0051)
HEJKOICF_01453 6.9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEJKOICF_01454 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HEJKOICF_01455 2e-110 XK27_05795 P ABC transporter permease
HEJKOICF_01456 9e-142 ET Bacterial periplasmic substrate-binding proteins
HEJKOICF_01457 1.3e-11 qacC P COG2076 Membrane transporters of cations and cationic drugs
HEJKOICF_01469 6.3e-196 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
HEJKOICF_01470 1e-181 C Zinc-binding dehydrogenase
HEJKOICF_01471 6.6e-100 proW P ABC transporter, permease protein
HEJKOICF_01472 4.2e-141 proV E ABC transporter, ATP-binding protein
HEJKOICF_01473 1.8e-108 proWZ P ABC transporter permease
HEJKOICF_01474 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
HEJKOICF_01475 1.6e-76 K Transcriptional regulator
HEJKOICF_01476 1.6e-73 O OsmC-like protein
HEJKOICF_01477 7.4e-76 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HEJKOICF_01478 2.2e-25 C Flavodoxin
HEJKOICF_01479 7.9e-67 GM NmrA-like family
HEJKOICF_01480 9.3e-30 GM NmrA-like family
HEJKOICF_01481 5.7e-45 K transcriptional regulator
HEJKOICF_01482 7.9e-108 L Integrase
HEJKOICF_01483 8.8e-70 ydjP I Alpha/beta hydrolase family
HEJKOICF_01484 3.9e-49 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HEJKOICF_01485 4.1e-75 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HEJKOICF_01486 9e-40 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HEJKOICF_01488 3e-12 L Transposase
HEJKOICF_01489 5.7e-56 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEJKOICF_01490 4.2e-37 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEJKOICF_01491 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEJKOICF_01499 7.3e-08
HEJKOICF_01500 8.7e-101 S D5 N terminal like
HEJKOICF_01501 2.5e-147 L DNA replication protein
HEJKOICF_01504 2.5e-07 S Helix-turn-helix domain
HEJKOICF_01505 1.2e-140 K Helix-turn-helix XRE-family like proteins
HEJKOICF_01506 8.6e-196 L Belongs to the 'phage' integrase family
HEJKOICF_01507 1.5e-124 L Transposase
HEJKOICF_01508 1e-91 P Cadmium resistance transporter
HEJKOICF_01509 1.3e-73 ydzE EG EamA-like transporter family
HEJKOICF_01510 2.3e-184 isdH M Iron Transport-associated domain
HEJKOICF_01511 2.3e-94 M Iron Transport-associated domain
HEJKOICF_01512 2.8e-149 isdE P Periplasmic binding protein
HEJKOICF_01513 7.5e-153 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEJKOICF_01514 5.4e-141 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
HEJKOICF_01515 2.6e-236 kgtP EGP Sugar (and other) transporter
HEJKOICF_01516 6.7e-30 M domain protein
HEJKOICF_01517 1.3e-27
HEJKOICF_01518 4.9e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HEJKOICF_01519 2.4e-121 L transposase, IS605 OrfB family
HEJKOICF_01520 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HEJKOICF_01521 1.1e-205 yfnA E Amino Acid
HEJKOICF_01522 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HEJKOICF_01523 1.7e-105 gmk2 2.7.4.8 F Guanylate kinase
HEJKOICF_01524 6.8e-83 zur P Belongs to the Fur family
HEJKOICF_01526 1.4e-167
HEJKOICF_01527 8.1e-188 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HEJKOICF_01528 1.9e-92 K Transcriptional regulator (TetR family)
HEJKOICF_01529 2.2e-205 V domain protein
HEJKOICF_01530 2e-80 K FR47-like protein
HEJKOICF_01531 7.8e-299 ybeC E amino acid
HEJKOICF_01532 8e-134 pnuC H nicotinamide mononucleotide transporter
HEJKOICF_01533 4e-209 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HEJKOICF_01534 5e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEJKOICF_01535 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HEJKOICF_01536 4.3e-118 dedA S SNARE associated Golgi protein
HEJKOICF_01537 0.0 helD 3.6.4.12 L DNA helicase
HEJKOICF_01538 7.3e-161 EG EamA-like transporter family
HEJKOICF_01539 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEJKOICF_01540 3.4e-135 IQ Dehydrogenase reductase
HEJKOICF_01541 1.1e-103 2.3.1.128 K acetyltransferase
HEJKOICF_01542 5.9e-174 coaA 2.7.1.33 F Pantothenic acid kinase
HEJKOICF_01543 3.8e-131 sptS 2.7.13.3 T Histidine kinase
HEJKOICF_01544 2.3e-79 K response regulator
HEJKOICF_01545 2e-114 2.7.6.5 T Region found in RelA / SpoT proteins
HEJKOICF_01546 5.7e-270 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HEJKOICF_01547 0.0 norZ 1.7.2.5 P Cytochrome C and Quinol oxidase polypeptide I
HEJKOICF_01548 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HEJKOICF_01549 1.4e-82
HEJKOICF_01550 8e-105 S Domain of unknown function (DUF4767)
HEJKOICF_01551 4.7e-54 K Helix-turn-helix domain
HEJKOICF_01552 5.1e-173 1.3.1.9 S Nitronate monooxygenase
HEJKOICF_01554 1.5e-79 rocF 3.5.3.1, 3.5.3.11 E Arginase family
HEJKOICF_01555 1.9e-53 ybjQ S Belongs to the UPF0145 family
HEJKOICF_01556 1.9e-223 dxs 2.2.1.7 HI 1-deoxy-D-xylulose-5-phosphate synthase
HEJKOICF_01557 6.1e-123 bm3R1 K Bacterial regulatory proteins, tetR family
HEJKOICF_01558 0.0 yhcA V ABC transporter, ATP-binding protein
HEJKOICF_01559 1.4e-54 S FMN_bind
HEJKOICF_01560 4e-159 M Membrane
HEJKOICF_01561 3.9e-22 XK27_06785 V ABC transporter
HEJKOICF_01562 2.2e-102 K Transcriptional regulator
HEJKOICF_01563 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEJKOICF_01564 2.1e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEJKOICF_01565 4.7e-260 argH 4.3.2.1 E argininosuccinate lyase
HEJKOICF_01566 1.1e-50 lacA S transferase hexapeptide repeat
HEJKOICF_01567 6.5e-156 L Thioesterase-like superfamily
HEJKOICF_01568 7.6e-11 S NADPH-dependent FMN reductase
HEJKOICF_01569 1.3e-09 S NADPH-dependent FMN reductase
HEJKOICF_01570 3.9e-40 S NADPH-dependent FMN reductase
HEJKOICF_01571 5.2e-241 yfnA E amino acid
HEJKOICF_01572 6.7e-243 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEJKOICF_01574 5.3e-17 mleP3 S Membrane transport protein
HEJKOICF_01575 9.5e-19 tnp L MULE transposase domain
HEJKOICF_01576 4.6e-123 L Belongs to the 'phage' integrase family
HEJKOICF_01578 7.9e-79 copY K Copper transport repressor CopY TcrY
HEJKOICF_01579 8.2e-39
HEJKOICF_01580 4.4e-169 GK ROK family
HEJKOICF_01581 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
HEJKOICF_01582 2.4e-311 ubiB S ABC1 family
HEJKOICF_01583 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
HEJKOICF_01584 4.9e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEJKOICF_01585 3.2e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEJKOICF_01586 2.9e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEJKOICF_01587 2.4e-43 repA S Replication initiator protein A
HEJKOICF_01588 8.3e-87 L Integrase core domain
HEJKOICF_01589 3.1e-210 M domain protein
HEJKOICF_01590 9.9e-45 K helix_turn_helix multiple antibiotic resistance protein
HEJKOICF_01591 5.8e-52 K DNA-templated transcription, initiation
HEJKOICF_01592 4.3e-17 K DNA-templated transcription, initiation
HEJKOICF_01594 0.0 V Type II restriction enzyme, methylase subunits
HEJKOICF_01595 0.0 L helicase superfamily c-terminal domain
HEJKOICF_01596 8.9e-39 yhjX P Major Facilitator Superfamily
HEJKOICF_01597 8.3e-35 S Protein of unknown function (DUF4256)
HEJKOICF_01598 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HEJKOICF_01599 7.9e-208 EGP Major facilitator Superfamily
HEJKOICF_01600 2.7e-211 ycsG P Natural resistance-associated macrophage protein
HEJKOICF_01601 1.6e-124 ycsF S LamB/YcsF family
HEJKOICF_01602 7.6e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HEJKOICF_01603 4.8e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEJKOICF_01604 2.2e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HEJKOICF_01605 1.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
HEJKOICF_01606 2.3e-72 K helix_turn_helix, mercury resistance
HEJKOICF_01607 5.9e-82 S Psort location Cytoplasmic, score
HEJKOICF_01608 1.6e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HEJKOICF_01609 3.4e-94 wecD K Acetyltransferase (GNAT) family
HEJKOICF_01610 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
HEJKOICF_01611 1e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
HEJKOICF_01612 2.5e-22 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HEJKOICF_01613 5e-38 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
HEJKOICF_01614 5.5e-87 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
HEJKOICF_01615 1.2e-64 pucR QT Purine catabolism regulatory protein-like family
HEJKOICF_01616 4.1e-134 allB 3.5.2.5 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEJKOICF_01617 1.7e-98 allC 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M20/M25/M40
HEJKOICF_01618 2.7e-202 allD 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HEJKOICF_01619 6e-19 sucD 6.2.1.5 C CoA-ligase
HEJKOICF_01620 1.7e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HEJKOICF_01621 3e-124 C nitroreductase
HEJKOICF_01622 4.6e-137 E GDSL-like Lipase/Acylhydrolase family
HEJKOICF_01623 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
HEJKOICF_01624 2.1e-196 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HEJKOICF_01625 0.0 pepN 3.4.11.2 E aminopeptidase
HEJKOICF_01626 5.5e-80 tlpA2 L Transposase IS200 like
HEJKOICF_01628 8e-235 G Polysaccharide deacetylase
HEJKOICF_01629 3e-145 XK26_04895
HEJKOICF_01630 1.8e-12 S Protein of unknown function (DUF3892)
HEJKOICF_01631 1.4e-77 3.1.21.3 V Type I restriction modification DNA specificity domain
HEJKOICF_01632 1.1e-305 hsdM 2.1.1.72 V type I restriction-modification system
HEJKOICF_01633 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HEJKOICF_01634 8.1e-150 prrC S AAA domain
HEJKOICF_01635 1.7e-42 tnpR L Resolvase, N terminal domain
HEJKOICF_01636 1.1e-21 aRA11 1.1.1.346 S Aldo/keto reductase family
HEJKOICF_01638 7.7e-89 tnpR L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HEJKOICF_01639 1.8e-51 2.7.13.3 T Histidine kinase
HEJKOICF_01640 5.2e-46 T regulator
HEJKOICF_01642 5.3e-99 cmk 2.7.4.25, 5.3.1.12 F AAA domain
HEJKOICF_01643 2.5e-84 V ABC transporter, ATP-binding protein
HEJKOICF_01644 6.8e-216 V ABC transporter (Permease)
HEJKOICF_01645 9.5e-236 L Transposase
HEJKOICF_01646 1.3e-54 S AAA ATPase domain
HEJKOICF_01647 4.6e-252 G Major Facilitator
HEJKOICF_01648 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HEJKOICF_01649 1.2e-177 K Transcriptional regulator, LacI family
HEJKOICF_01650 1.2e-156 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HEJKOICF_01651 4.6e-09
HEJKOICF_01652 6e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HEJKOICF_01654 1.1e-57 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HEJKOICF_01655 8.8e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEJKOICF_01657 6.1e-183 fecB P Periplasmic binding protein
HEJKOICF_01658 9.3e-272 sufB O assembly protein SufB
HEJKOICF_01659 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
HEJKOICF_01660 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEJKOICF_01661 4.5e-244 sufD O FeS assembly protein SufD
HEJKOICF_01662 8.5e-145 sufC O FeS assembly ATPase SufC
HEJKOICF_01663 1.4e-33 feoA P FeoA domain
HEJKOICF_01664 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HEJKOICF_01665 6.7e-23 S Virus attachment protein p12 family
HEJKOICF_01666 2.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HEJKOICF_01667 2.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HEJKOICF_01668 2.3e-56 ycsI S Protein of unknown function (DUF1445)
HEJKOICF_01669 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HEJKOICF_01670 9.5e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEJKOICF_01671 5.6e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEJKOICF_01672 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HEJKOICF_01673 1.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEJKOICF_01674 1.7e-153 yitU 3.1.3.104 S hydrolase
HEJKOICF_01675 9.7e-274 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HEJKOICF_01676 6.1e-57 tlpA2 L Transposase IS200 like
HEJKOICF_01677 1.8e-75 argR K Regulates arginine biosynthesis genes
HEJKOICF_01678 5.5e-124 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HEJKOICF_01679 7.3e-157 hrtB V ABC transporter permease
HEJKOICF_01680 1.1e-107 ygfC K Bacterial regulatory proteins, tetR family
HEJKOICF_01681 2.4e-189 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HEJKOICF_01682 1.4e-281 mntH P H( )-stimulated, divalent metal cation uptake system
HEJKOICF_01683 2.2e-22
HEJKOICF_01684 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEJKOICF_01685 2.4e-70 L nuclease
HEJKOICF_01686 8.4e-162 F DNA/RNA non-specific endonuclease
HEJKOICF_01687 1.7e-44 L Transposase IS200 like
HEJKOICF_01688 1.3e-307 recN L May be involved in recombinational repair of damaged DNA
HEJKOICF_01689 6.2e-76 argR K Regulates arginine biosynthesis genes
HEJKOICF_01690 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HEJKOICF_01691 9.6e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HEJKOICF_01692 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEJKOICF_01693 6.1e-258 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEJKOICF_01694 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEJKOICF_01695 4e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEJKOICF_01696 4.1e-72 yqhY S Asp23 family, cell envelope-related function
HEJKOICF_01697 4e-206 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HEJKOICF_01698 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HEJKOICF_01699 9e-53 ysxB J Cysteine protease Prp
HEJKOICF_01700 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HEJKOICF_01701 4.8e-114 K Transcriptional regulator
HEJKOICF_01703 6.6e-93 dut S Protein conserved in bacteria
HEJKOICF_01704 5.4e-178
HEJKOICF_01705 2.2e-149
HEJKOICF_01706 4.7e-13
HEJKOICF_01707 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
HEJKOICF_01708 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEJKOICF_01709 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
HEJKOICF_01710 1.5e-71 yqhL P Rhodanese-like protein
HEJKOICF_01711 5.7e-180 glk 2.7.1.2 G Glucokinase
HEJKOICF_01712 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HEJKOICF_01713 2e-115 gluP 3.4.21.105 S Peptidase, S54 family
HEJKOICF_01714 9.2e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEJKOICF_01715 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEJKOICF_01716 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HEJKOICF_01717 0.0 S membrane
HEJKOICF_01718 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEJKOICF_01719 1.4e-116 udk 2.7.1.48 F Cytidine monophosphokinase
HEJKOICF_01720 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEJKOICF_01721 5.1e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEJKOICF_01722 7.8e-60 yodB K Transcriptional regulator, HxlR family
HEJKOICF_01723 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HEJKOICF_01724 1.3e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEJKOICF_01725 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HEJKOICF_01726 1.6e-131 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEJKOICF_01727 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HEJKOICF_01728 1.6e-233 V MatE
HEJKOICF_01729 1.5e-280 arlS 2.7.13.3 T Histidine kinase
HEJKOICF_01730 5.6e-121 K response regulator
HEJKOICF_01731 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HEJKOICF_01732 4.6e-97 yceD S Uncharacterized ACR, COG1399
HEJKOICF_01733 1.4e-214 ylbM S Belongs to the UPF0348 family
HEJKOICF_01734 1.8e-141 yqeM Q Methyltransferase
HEJKOICF_01735 6.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEJKOICF_01736 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HEJKOICF_01737 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEJKOICF_01738 2.6e-49 yhbY J RNA-binding protein
HEJKOICF_01739 2.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
HEJKOICF_01740 8.4e-96 yqeG S HAD phosphatase, family IIIA
HEJKOICF_01741 1.4e-25 yoaK S Protein of unknown function (DUF1275)
HEJKOICF_01742 3.6e-18 yoaK S Protein of unknown function (DUF1275)
HEJKOICF_01743 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEJKOICF_01744 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HEJKOICF_01745 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEJKOICF_01746 2.5e-172 dnaI L Primosomal protein DnaI
HEJKOICF_01747 3e-251 dnaB L replication initiation and membrane attachment
HEJKOICF_01748 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEJKOICF_01749 3.5e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEJKOICF_01750 1.4e-161 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEJKOICF_01751 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEJKOICF_01752 5e-139 aroD S Serine hydrolase (FSH1)
HEJKOICF_01754 2.4e-149 recT L RecT family
HEJKOICF_01758 1.4e-10 S Domain of unknown function (DUF771)
HEJKOICF_01759 1.5e-33 S Uncharacterized protein conserved in bacteria (DUF2188)
HEJKOICF_01760 5e-24
HEJKOICF_01763 2.5e-117 K Phage regulatory protein
HEJKOICF_01764 1.6e-28 S sequence-specific DNA binding
HEJKOICF_01765 5.1e-17 3.4.21.88 K Helix-turn-helix XRE-family like proteins
HEJKOICF_01767 4.1e-101 kcsA P Ion transport protein
HEJKOICF_01768 1.5e-57
HEJKOICF_01769 4.1e-24 S Protein of unknown function (DUF4231)
HEJKOICF_01770 3.9e-67 S MTH538 TIR-like domain (DUF1863)
HEJKOICF_01771 4.8e-28
HEJKOICF_01772 7.6e-44 2.7.11.1 NU Domain of unknown function (DUF5067)
HEJKOICF_01776 7.8e-157 L hmm pf00665
HEJKOICF_01777 4.4e-49 tnp L MULE transposase domain
HEJKOICF_01779 1.5e-91 S Cupin superfamily (DUF985)
HEJKOICF_01780 1.8e-122 K response regulator
HEJKOICF_01781 5.9e-208 hpk31 2.7.13.3 T Histidine kinase
HEJKOICF_01782 1e-203 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HEJKOICF_01783 7.4e-147 azlC E AzlC protein
HEJKOICF_01784 8.9e-61 azlD S branched-chain amino acid
HEJKOICF_01785 2.6e-100 ydeN S Serine hydrolase
HEJKOICF_01786 9.8e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HEJKOICF_01787 1.2e-72 XK27_08315 M Sulfatase
HEJKOICF_01788 4e-190 XK27_08315 M Sulfatase
HEJKOICF_01789 2.7e-139 yihY S Belongs to the UPF0761 family
HEJKOICF_01790 3.8e-31 S Protein of unknown function (DUF2922)
HEJKOICF_01791 1.3e-07
HEJKOICF_01792 3.2e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
HEJKOICF_01793 1.1e-118 rfbP M Bacterial sugar transferase
HEJKOICF_01794 1.1e-146 cps1D M Domain of unknown function (DUF4422)
HEJKOICF_01795 2.4e-212 cps3F
HEJKOICF_01796 5.4e-41 ywqC M biosynthesis protein
HEJKOICF_01797 1.2e-130 S Membrane
HEJKOICF_01798 4.6e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEJKOICF_01799 1.3e-11 S YjcQ protein
HEJKOICF_01801 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEJKOICF_01802 6.4e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEJKOICF_01803 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
HEJKOICF_01804 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEJKOICF_01805 2.6e-126 tnp L DDE domain
HEJKOICF_01806 3.1e-248 S Uncharacterized protein conserved in bacteria (DUF2252)
HEJKOICF_01807 4.5e-301 scrB 3.2.1.26 GH32 G invertase
HEJKOICF_01808 1e-195 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HEJKOICF_01809 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HEJKOICF_01810 3.6e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEJKOICF_01811 1.1e-11 L hmm pf00665
HEJKOICF_01812 1.9e-65 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEJKOICF_01813 2.1e-292 norB EGP Major Facilitator
HEJKOICF_01814 7.3e-98 K Bacterial regulatory proteins, tetR family
HEJKOICF_01815 1e-51 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HEJKOICF_01816 2e-64
HEJKOICF_01817 1.4e-53
HEJKOICF_01818 1.7e-216 S Domain of unknown function (DUF389)
HEJKOICF_01819 1.5e-237 yagE E Amino acid permease
HEJKOICF_01820 8.3e-78 tnp L DDE domain
HEJKOICF_01821 6.2e-185 hoxN U High-affinity nickel-transport protein
HEJKOICF_01822 1.7e-148 larE S NAD synthase
HEJKOICF_01823 4.5e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HEJKOICF_01824 2.4e-216 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HEJKOICF_01825 1.7e-131 cpmA S AIR carboxylase
HEJKOICF_01826 3.6e-241 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HEJKOICF_01827 7e-124 K Crp-like helix-turn-helix domain
HEJKOICF_01828 1.4e-49
HEJKOICF_01829 1.4e-148 lmrP E Major Facilitator Superfamily
HEJKOICF_01830 1e-41 lmrP E Major Facilitator Superfamily
HEJKOICF_01831 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HEJKOICF_01832 1.2e-74 rplI J Binds to the 23S rRNA
HEJKOICF_01833 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HEJKOICF_01834 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEJKOICF_01835 6.4e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEJKOICF_01836 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HEJKOICF_01837 9.5e-19 tnp L MULE transposase domain
HEJKOICF_01838 4.6e-21 K Cro/C1-type HTH DNA-binding domain
HEJKOICF_01839 1.6e-44
HEJKOICF_01840 8e-58 L Type II restriction endonuclease, Alw26I Eco31I Esp3I family
HEJKOICF_01841 1.7e-89 2.1.1.37, 3.1.21.3 L C-5 cytosine-specific DNA methylase
HEJKOICF_01842 1.4e-49 K TRANSCRIPTIONal
HEJKOICF_01843 4.7e-20 tra L Transposase and inactivated derivatives, IS30 family
HEJKOICF_01844 9.5e-19 tnp L MULE transposase domain
HEJKOICF_01845 1.1e-37 L Transposase
HEJKOICF_01846 2.2e-204 waaB GT4 M Glycosyl transferases group 1
HEJKOICF_01847 7.8e-221 glf 5.4.99.9 M UDP-galactopyranose mutase
HEJKOICF_01848 2.5e-264 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HEJKOICF_01849 7.1e-189 GT2 M Glycosyltransferase like family 2
HEJKOICF_01850 7.4e-200 cps3I G Acyltransferase family
HEJKOICF_01867 2.9e-137 L Transposase and inactivated derivatives, IS30 family
HEJKOICF_01871 3.5e-16 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HEJKOICF_01872 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEJKOICF_01873 4.5e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HEJKOICF_01874 9.4e-205 coiA 3.6.4.12 S Competence protein
HEJKOICF_01875 1.8e-113 yjbH Q Thioredoxin
HEJKOICF_01876 1e-122 yjbM 2.7.6.5 S RelA SpoT domain protein
HEJKOICF_01877 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEJKOICF_01878 7e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HEJKOICF_01879 4e-195 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HEJKOICF_01880 3.3e-163 rrmA 2.1.1.187 H Methyltransferase
HEJKOICF_01881 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEJKOICF_01882 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HEJKOICF_01883 1.2e-07 S Protein of unknown function (DUF4044)
HEJKOICF_01884 5.8e-58
HEJKOICF_01885 5.6e-79 mraZ K Belongs to the MraZ family
HEJKOICF_01886 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEJKOICF_01887 3.5e-08 ftsL D Cell division protein FtsL
HEJKOICF_01888 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HEJKOICF_01889 9.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEJKOICF_01890 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEJKOICF_01891 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEJKOICF_01892 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEJKOICF_01893 3.2e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEJKOICF_01894 3.8e-219 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEJKOICF_01895 2.5e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEJKOICF_01896 6.8e-41 yggT S YGGT family
HEJKOICF_01897 4.9e-145 ylmH S S4 domain protein
HEJKOICF_01898 4.8e-112 divIVA D DivIVA domain protein
HEJKOICF_01900 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEJKOICF_01901 1.2e-32 cspB K Cold shock protein
HEJKOICF_01902 7.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HEJKOICF_01904 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEJKOICF_01905 3.4e-58 XK27_04120 S Putative amino acid metabolism
HEJKOICF_01906 6.5e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEJKOICF_01907 4.6e-307 S amidohydrolase
HEJKOICF_01908 4e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HEJKOICF_01909 4.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HEJKOICF_01910 7.1e-124 S Repeat protein
HEJKOICF_01911 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEJKOICF_01912 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEJKOICF_01913 4.2e-74 spx4 1.20.4.1 P ArsC family
HEJKOICF_01914 5.8e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HEJKOICF_01915 2.2e-31 ykzG S Belongs to the UPF0356 family
HEJKOICF_01916 1.2e-74
HEJKOICF_01917 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEJKOICF_01918 2.4e-49 yktA S Belongs to the UPF0223 family
HEJKOICF_01919 4e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HEJKOICF_01920 0.0 typA T GTP-binding protein TypA
HEJKOICF_01921 2.8e-216 ftsW D Belongs to the SEDS family
HEJKOICF_01922 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HEJKOICF_01923 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HEJKOICF_01924 9.6e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEJKOICF_01925 1.1e-197 ylbL T Belongs to the peptidase S16 family
HEJKOICF_01926 2.2e-81 tlpA2 L Transposase IS200 like
HEJKOICF_01927 2.7e-27 C Aldo/keto reductase family
HEJKOICF_01930 2.7e-85 C Aldo keto reductase
HEJKOICF_01931 9e-79 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEJKOICF_01933 3.6e-27 S Alpha/beta hydrolase family
HEJKOICF_01934 3e-55 S Alpha/beta hydrolase family
HEJKOICF_01935 7.8e-120 pnb C nitroreductase
HEJKOICF_01936 2.1e-22 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HEJKOICF_01937 2.7e-43 S Tautomerase enzyme
HEJKOICF_01938 3.6e-29 S Domain of unknown function (DUF4767)
HEJKOICF_01939 4.1e-37 L Helix-turn-helix domain
HEJKOICF_01940 9.5e-19 tnp L MULE transposase domain
HEJKOICF_01941 8.5e-96 K transcriptional regulator
HEJKOICF_01942 4.3e-139 lmrB EGP Major facilitator Superfamily
HEJKOICF_01944 4.4e-12 yfjR K Psort location Cytoplasmic, score
HEJKOICF_01945 3.5e-38 S Cytochrome B5
HEJKOICF_01946 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEJKOICF_01947 4.9e-215 2.1.1.14 E methionine synthase, vitamin-B12 independent
HEJKOICF_01948 1.2e-64
HEJKOICF_01949 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HEJKOICF_01950 5.6e-33 copZ P Heavy-metal-associated domain
HEJKOICF_01951 5.4e-46 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
HEJKOICF_01952 4.1e-113 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HEJKOICF_01953 6.4e-90 L Transposase
HEJKOICF_01954 6.9e-118 L Integrase core domain
HEJKOICF_01955 3.7e-96 pgi 5.3.1.9 G Belongs to the GPI family
HEJKOICF_01956 5.8e-171 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HEJKOICF_01957 2.5e-234 mepA V MATE efflux family protein
HEJKOICF_01958 9.7e-225 amtB P ammonium transporter
HEJKOICF_01959 6.3e-196 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEJKOICF_01960 4.3e-42 L hmm pf00665
HEJKOICF_01961 2.4e-130 L PFAM Integrase catalytic region
HEJKOICF_01962 9.1e-220 L Transposase
HEJKOICF_01963 4.9e-154 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HEJKOICF_01964 2.2e-146 cylB V ABC-2 type transporter
HEJKOICF_01965 5.5e-133 ybbM S Uncharacterised protein family (UPF0014)
HEJKOICF_01966 1.5e-112 ybbL S ABC transporter, ATP-binding protein
HEJKOICF_01967 4.3e-46 rmeB K transcriptional regulator, MerR family
HEJKOICF_01968 7.4e-36 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
HEJKOICF_01969 3.3e-76 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEJKOICF_01970 1e-56 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
HEJKOICF_01971 2.3e-54 tlpA2 L Transposase IS200 like
HEJKOICF_01972 1.3e-90 comEA L Competence protein ComEA
HEJKOICF_01973 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
HEJKOICF_01974 0.0 comEC S Competence protein ComEC
HEJKOICF_01975 4.1e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HEJKOICF_01976 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
HEJKOICF_01977 2.2e-22 L hmm pf00665
HEJKOICF_01978 2.4e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEJKOICF_01980 6.4e-90 L Transposase
HEJKOICF_01981 2.5e-12
HEJKOICF_01982 4.2e-47 M Acetyltransferase (Isoleucine patch superfamily)
HEJKOICF_01983 3.1e-125 tnp L MULE transposase domain
HEJKOICF_01984 2.7e-85 L PFAM Integrase catalytic region
HEJKOICF_01985 5.9e-79 L PFAM transposase, IS4 family protein
HEJKOICF_01986 1.9e-132 XK27_07210 6.1.1.6 S B3 4 domain
HEJKOICF_01987 2.7e-120 J 2'-5' RNA ligase superfamily
HEJKOICF_01989 4e-41 S ABC-type cobalt transport system, permease component
HEJKOICF_01990 2.5e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEJKOICF_01991 2.5e-44 IQ reductase
HEJKOICF_01992 2e-11 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEJKOICF_01993 1.4e-33 L PFAM Integrase catalytic region
HEJKOICF_01994 1.2e-51 L Transposase
HEJKOICF_01995 8e-91 L Transposase
HEJKOICF_01996 3.6e-80 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
HEJKOICF_01997 3.2e-127 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HEJKOICF_01998 2.1e-56 casE S CRISPR_assoc
HEJKOICF_01999 7e-66 casD S CRISPR-associated protein (Cas_Cas5)
HEJKOICF_02000 9e-129 casC L CT1975-like protein
HEJKOICF_02001 5.4e-40 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
HEJKOICF_02002 8.5e-155 casA L the current gene model (or a revised gene model) may contain a frame shift
HEJKOICF_02003 6.9e-295 cas3 L CRISPR-associated helicase cas3
HEJKOICF_02004 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEJKOICF_02005 3.7e-260 yfnA E Amino Acid
HEJKOICF_02006 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HEJKOICF_02007 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEJKOICF_02008 5.4e-40 ylqC S Belongs to the UPF0109 family
HEJKOICF_02009 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HEJKOICF_02010 3.1e-122 phoU P Plays a role in the regulation of phosphate uptake
HEJKOICF_02011 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEJKOICF_02012 1.6e-152 pstA P Phosphate transport system permease protein PstA
HEJKOICF_02013 4.7e-152 pstC P probably responsible for the translocation of the substrate across the membrane
HEJKOICF_02014 2.5e-158 pstS P Phosphate
HEJKOICF_02015 9.8e-129 K Transcriptional regulatory protein, C-terminal domain protein
HEJKOICF_02016 1e-30
HEJKOICF_02017 2.4e-26
HEJKOICF_02019 5.8e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEJKOICF_02020 8.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEJKOICF_02021 2.5e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEJKOICF_02022 0.0 smc D Required for chromosome condensation and partitioning
HEJKOICF_02023 4e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEJKOICF_02024 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEJKOICF_02025 2.8e-164 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEJKOICF_02026 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEJKOICF_02027 2.7e-305 yloV S DAK2 domain fusion protein YloV
HEJKOICF_02028 3.6e-58 asp S Asp23 family, cell envelope-related function
HEJKOICF_02029 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HEJKOICF_02030 2.5e-126 thiN 2.7.6.2 H thiamine pyrophosphokinase
HEJKOICF_02031 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HEJKOICF_02032 3.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEJKOICF_02033 0.0 KLT serine threonine protein kinase
HEJKOICF_02034 2.2e-131 stp 3.1.3.16 T phosphatase
HEJKOICF_02035 2e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEJKOICF_02036 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEJKOICF_02037 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEJKOICF_02038 5e-221 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEJKOICF_02039 1.2e-45 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEJKOICF_02040 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HEJKOICF_02041 3.3e-15
HEJKOICF_02042 0.0 copB 3.6.3.4 P P-type ATPase
HEJKOICF_02043 6.5e-75 K Copper transport repressor CopY TcrY
HEJKOICF_02045 9.5e-19 tnp L MULE transposase domain
HEJKOICF_02046 7.6e-42 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEJKOICF_02047 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEJKOICF_02048 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEJKOICF_02049 1.2e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HEJKOICF_02050 2e-46 L Transposase
HEJKOICF_02052 1.1e-253 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HEJKOICF_02053 4.4e-255 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HEJKOICF_02054 1.1e-52 trxA O Belongs to the thioredoxin family
HEJKOICF_02055 1e-120 mleP3 S Membrane transport protein
HEJKOICF_02056 4.4e-51 L transposase, IS605 OrfB family
HEJKOICF_02057 2.3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HEJKOICF_02058 6.1e-209 EG GntP family permease
HEJKOICF_02059 3.8e-105 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HEJKOICF_02060 1.9e-224 emrY EGP Major facilitator Superfamily
HEJKOICF_02061 1.1e-175 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HEJKOICF_02062 7.3e-71 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEJKOICF_02063 3.5e-85 2.5.1.105 P Cation efflux family
HEJKOICF_02064 9e-52 L Resolvase, N terminal domain
HEJKOICF_02065 4.2e-89 L Transposase
HEJKOICF_02066 7e-113 S EcsC protein family
HEJKOICF_02067 6.9e-195 tra L Transposase and inactivated derivatives, IS30 family
HEJKOICF_02068 1.2e-34 S Protein of unknown function (DUF3021)
HEJKOICF_02069 1.7e-30 K LytTr DNA-binding domain
HEJKOICF_02070 8.2e-140 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HEJKOICF_02071 2e-94 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEJKOICF_02072 1.4e-26 L Psort location Cytoplasmic, score
HEJKOICF_02075 7.6e-108 T Calcineurin-like phosphoesterase superfamily domain
HEJKOICF_02076 5.9e-212 G Major Facilitator Superfamily
HEJKOICF_02079 1e-56
HEJKOICF_02081 7.4e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HEJKOICF_02082 6.3e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEJKOICF_02083 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
HEJKOICF_02084 1.8e-122 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HEJKOICF_02085 1e-84 K GNAT family
HEJKOICF_02087 6.3e-257 pgi 5.3.1.9 G Belongs to the GPI family
HEJKOICF_02088 4.3e-183 fruR3 K Transcriptional regulator, LacI family
HEJKOICF_02089 2.5e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HEJKOICF_02090 2.6e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEJKOICF_02091 1e-56 trxA1 O Belongs to the thioredoxin family
HEJKOICF_02092 2.3e-142 terC P membrane
HEJKOICF_02093 9.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEJKOICF_02094 1.4e-170 corA P CorA-like Mg2+ transporter protein
HEJKOICF_02095 2.1e-228 pbuX F xanthine permease
HEJKOICF_02096 1.9e-150 qorB 1.6.5.2 GM NmrA-like family
HEJKOICF_02097 2.5e-126 pgm3 G phosphoglycerate mutase family
HEJKOICF_02098 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEJKOICF_02099 2e-85
HEJKOICF_02100 7.4e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HEJKOICF_02101 2e-100 dps P Belongs to the Dps family
HEJKOICF_02102 2.8e-32 copZ P Heavy-metal-associated domain
HEJKOICF_02103 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HEJKOICF_02104 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HEJKOICF_02105 2e-180 iunH2 3.2.2.1 F nucleoside hydrolase
HEJKOICF_02106 1.6e-100 S ABC-type cobalt transport system, permease component
HEJKOICF_02107 2.1e-255 cbiO1 S ABC transporter, ATP-binding protein
HEJKOICF_02108 5.7e-115 P Cobalt transport protein
HEJKOICF_02109 1.2e-16 yvlA
HEJKOICF_02110 0.0 yjcE P Sodium proton antiporter
HEJKOICF_02111 1.1e-192 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HEJKOICF_02112 1.6e-73 O OsmC-like protein
HEJKOICF_02113 2.8e-187 D Alpha beta
HEJKOICF_02114 8.4e-75 K Transcriptional regulator
HEJKOICF_02115 4.5e-160
HEJKOICF_02116 6.6e-20
HEJKOICF_02117 2.1e-59
HEJKOICF_02118 3.1e-75 uspA T universal stress protein
HEJKOICF_02120 9.7e-130 qmcA O prohibitin homologues
HEJKOICF_02121 5.5e-245 glpT G Major Facilitator Superfamily
HEJKOICF_02122 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEJKOICF_02123 2.3e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HEJKOICF_02124 6.4e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HEJKOICF_02125 1.8e-126 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEJKOICF_02126 4.3e-58 L hmm pf00665
HEJKOICF_02127 9.3e-79 D Cellulose biosynthesis protein BcsQ
HEJKOICF_02128 8.2e-61 xerC L Phage integrase, N-terminal SAM-like domain
HEJKOICF_02129 4.9e-52 ypaA S Protein of unknown function (DUF1304)
HEJKOICF_02130 5.5e-85 D Alpha beta
HEJKOICF_02131 1.8e-217 lacS G Transporter
HEJKOICF_02132 2.3e-83 lacR K Transcriptional regulator
HEJKOICF_02133 0.0 uvrA2 L ABC transporter
HEJKOICF_02134 1.3e-151 2.1.1.37 H C-5 cytosine-specific DNA methylase
HEJKOICF_02135 2.3e-117 L AlwI restriction endonuclease
HEJKOICF_02136 9.5e-19 tnp L MULE transposase domain
HEJKOICF_02137 3e-50 tnpR L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HEJKOICF_02138 1.3e-193 L Transposase and inactivated derivatives, IS30 family
HEJKOICF_02139 9.1e-76 S Short repeat of unknown function (DUF308)
HEJKOICF_02141 1.2e-43 L Protein of unknown function (DUF3991)
HEJKOICF_02142 1.9e-46 L Transposase
HEJKOICF_02143 9.7e-66 tnp L MULE transposase domain
HEJKOICF_02144 1.1e-65 S Fic/DOC family
HEJKOICF_02147 1.3e-218 iscS 2.8.1.7 E Aminotransferase class V
HEJKOICF_02148 1.3e-54 tlpA2 L Transposase IS200 like
HEJKOICF_02149 3.8e-16
HEJKOICF_02150 6e-12 S Transglycosylase associated protein
HEJKOICF_02151 1e-69 S Asp23 family, cell envelope-related function
HEJKOICF_02152 8.8e-88
HEJKOICF_02153 3.7e-38 L Transposase and inactivated derivatives
HEJKOICF_02154 9.8e-77

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)