ORF_ID e_value Gene_name EC_number CAZy COGs Description
HOCPNFDN_00001 2.5e-68 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HOCPNFDN_00002 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOCPNFDN_00003 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
HOCPNFDN_00004 0.0 tcaA S response to antibiotic
HOCPNFDN_00005 4.2e-124 exoY M Membrane
HOCPNFDN_00006 8.6e-113 yvbH S YvbH-like oligomerisation region
HOCPNFDN_00007 6.4e-103 yvbG U UPF0056 membrane protein
HOCPNFDN_00008 1.4e-98 yvbF K Belongs to the GbsR family
HOCPNFDN_00009 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HOCPNFDN_00010 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HOCPNFDN_00011 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HOCPNFDN_00012 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HOCPNFDN_00013 4.5e-45 sdpR K transcriptional
HOCPNFDN_00014 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HOCPNFDN_00015 4.4e-08
HOCPNFDN_00016 7.6e-172
HOCPNFDN_00017 7.9e-13 S Sporulation delaying protein SdpA
HOCPNFDN_00018 8.7e-61 yvbF K Belongs to the GbsR family
HOCPNFDN_00019 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HOCPNFDN_00020 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HOCPNFDN_00021 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HOCPNFDN_00022 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HOCPNFDN_00023 4.2e-226 NT chemotaxis protein
HOCPNFDN_00024 2.2e-54 yodB K transcriptional
HOCPNFDN_00025 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
HOCPNFDN_00026 4e-69 K transcriptional
HOCPNFDN_00027 7.5e-36 yvzC K Transcriptional
HOCPNFDN_00028 3.7e-153 yvaM S Serine aminopeptidase, S33
HOCPNFDN_00029 2.4e-23 secG U Preprotein translocase subunit SecG
HOCPNFDN_00030 5.6e-143 est 3.1.1.1 S Carboxylesterase
HOCPNFDN_00031 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HOCPNFDN_00032 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HOCPNFDN_00034 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_00035 4.1e-101 K Bacterial regulatory proteins, tetR family
HOCPNFDN_00036 2.8e-55 yvaE P Small Multidrug Resistance protein
HOCPNFDN_00037 5.7e-73 yvaD S Family of unknown function (DUF5360)
HOCPNFDN_00038 0.0 yvaC S Fusaric acid resistance protein-like
HOCPNFDN_00039 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HOCPNFDN_00040 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
HOCPNFDN_00041 2.2e-48 csoR S transcriptional
HOCPNFDN_00042 1.5e-29 copZ P Copper resistance protein CopZ
HOCPNFDN_00043 0.0 copA 3.6.3.54 P P-type ATPase
HOCPNFDN_00044 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HOCPNFDN_00045 1.6e-104 bdbD O Thioredoxin
HOCPNFDN_00046 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HOCPNFDN_00047 4.1e-107 yvgT S membrane
HOCPNFDN_00048 0.0 helD 3.6.4.12 L DNA helicase
HOCPNFDN_00049 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HOCPNFDN_00050 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HOCPNFDN_00051 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HOCPNFDN_00052 5.4e-86 yvgO
HOCPNFDN_00053 9.1e-158 yvgN S reductase
HOCPNFDN_00054 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
HOCPNFDN_00055 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HOCPNFDN_00056 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HOCPNFDN_00057 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HOCPNFDN_00058 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HOCPNFDN_00059 6.5e-16 S Small spore protein J (Spore_SspJ)
HOCPNFDN_00060 2.6e-237 yvsH E Arginine ornithine antiporter
HOCPNFDN_00062 2.1e-179 fhuD P ABC transporter
HOCPNFDN_00063 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_00064 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_00065 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HOCPNFDN_00066 4.8e-176 M Efflux transporter rnd family, mfp subunit
HOCPNFDN_00067 7.1e-124 macB V ABC transporter, ATP-binding protein
HOCPNFDN_00068 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HOCPNFDN_00069 1.3e-64 yvrL S Regulatory protein YrvL
HOCPNFDN_00070 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
HOCPNFDN_00071 2.4e-19 S YvrJ protein family
HOCPNFDN_00072 1.8e-96 yvrI K RNA polymerase
HOCPNFDN_00073 3.6e-22
HOCPNFDN_00074 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_00075 0.0 T PhoQ Sensor
HOCPNFDN_00076 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HOCPNFDN_00077 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_00078 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HOCPNFDN_00079 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_00080 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HOCPNFDN_00081 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
HOCPNFDN_00082 4.8e-227 yvqJ EGP Major facilitator Superfamily
HOCPNFDN_00083 5.6e-62 liaI S membrane
HOCPNFDN_00084 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HOCPNFDN_00085 9.3e-129 liaG S Putative adhesin
HOCPNFDN_00086 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HOCPNFDN_00087 5.5e-187 vraS 2.7.13.3 T Histidine kinase
HOCPNFDN_00088 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOCPNFDN_00089 4.6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
HOCPNFDN_00090 9.1e-198 gerAB E Spore germination protein
HOCPNFDN_00091 2.2e-247 gerAA EG Spore germination protein
HOCPNFDN_00092 2.3e-24 S Protein of unknown function (DUF3970)
HOCPNFDN_00093 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HOCPNFDN_00094 4.3e-158 yuxN K Transcriptional regulator
HOCPNFDN_00095 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HOCPNFDN_00096 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_00097 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HOCPNFDN_00098 1.2e-79 dps P Ferritin-like domain
HOCPNFDN_00099 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_00100 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
HOCPNFDN_00101 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
HOCPNFDN_00102 5.6e-66 S YusW-like protein
HOCPNFDN_00103 1e-153 yusV 3.6.3.34 HP ABC transporter
HOCPNFDN_00104 3.8e-47 yusU S Protein of unknown function (DUF2573)
HOCPNFDN_00105 2.7e-160 yusT K LysR substrate binding domain
HOCPNFDN_00106 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_00107 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_00108 8.4e-66 yusQ S Tautomerase enzyme
HOCPNFDN_00109 3.8e-293 yusP P Major facilitator superfamily
HOCPNFDN_00110 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
HOCPNFDN_00111 3.2e-53 yusN M Coat F domain
HOCPNFDN_00112 5.1e-40
HOCPNFDN_00113 2.2e-165 fadM E Proline dehydrogenase
HOCPNFDN_00114 4.7e-09 S YuzL-like protein
HOCPNFDN_00115 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HOCPNFDN_00116 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HOCPNFDN_00117 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HOCPNFDN_00118 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HOCPNFDN_00119 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HOCPNFDN_00120 1.1e-39 yusG S Protein of unknown function (DUF2553)
HOCPNFDN_00121 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HOCPNFDN_00122 5.6e-55 traF CO Thioredoxin
HOCPNFDN_00123 2.4e-56 yusD S SCP-2 sterol transfer family
HOCPNFDN_00124 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOCPNFDN_00125 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HOCPNFDN_00126 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
HOCPNFDN_00127 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HOCPNFDN_00128 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HOCPNFDN_00129 1.4e-245 sufD O assembly protein SufD
HOCPNFDN_00130 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HOCPNFDN_00131 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HOCPNFDN_00132 3.5e-271 sufB O FeS cluster assembly
HOCPNFDN_00134 1.1e-16 ydhU P Manganese containing catalase
HOCPNFDN_00135 8.7e-78 ydhU P Catalase
HOCPNFDN_00136 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HOCPNFDN_00137 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HOCPNFDN_00138 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HOCPNFDN_00139 3.9e-133 ydhQ K UTRA
HOCPNFDN_00140 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HOCPNFDN_00141 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOCPNFDN_00142 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HOCPNFDN_00143 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HOCPNFDN_00144 4.6e-200 pbuE EGP Major facilitator Superfamily
HOCPNFDN_00145 1.7e-99 ydhK M Protein of unknown function (DUF1541)
HOCPNFDN_00146 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HOCPNFDN_00147 4.1e-86 K Acetyltransferase (GNAT) domain
HOCPNFDN_00149 4.6e-69 frataxin S Domain of unknown function (DU1801)
HOCPNFDN_00150 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HOCPNFDN_00151 1.9e-127
HOCPNFDN_00152 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HOCPNFDN_00153 3.3e-244 ydhD M Glycosyl hydrolase
HOCPNFDN_00154 6.5e-122 ydhC K FCD
HOCPNFDN_00155 1.2e-121 ydhB S membrane transporter protein
HOCPNFDN_00156 2.5e-209 tcaB EGP Major facilitator Superfamily
HOCPNFDN_00157 1.1e-69 ydgJ K Winged helix DNA-binding domain
HOCPNFDN_00158 1e-113 drgA C nitroreductase
HOCPNFDN_00159 0.0 ydgH S drug exporters of the RND superfamily
HOCPNFDN_00160 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
HOCPNFDN_00161 4.6e-91 dinB S DinB family
HOCPNFDN_00162 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HOCPNFDN_00163 4.2e-308 expZ S ABC transporter
HOCPNFDN_00164 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
HOCPNFDN_00165 1.9e-53 S DoxX-like family
HOCPNFDN_00166 1.5e-101 K Bacterial regulatory proteins, tetR family
HOCPNFDN_00167 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HOCPNFDN_00168 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HOCPNFDN_00169 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
HOCPNFDN_00170 5.2e-122 ydfS S Protein of unknown function (DUF421)
HOCPNFDN_00171 4.4e-118 ydfR S Protein of unknown function (DUF421)
HOCPNFDN_00173 6.3e-29
HOCPNFDN_00174 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HOCPNFDN_00175 1.3e-57 traF CO Thioredoxin
HOCPNFDN_00176 8.8e-63 mhqP S DoxX
HOCPNFDN_00177 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HOCPNFDN_00178 9.6e-112 ydfN C nitroreductase
HOCPNFDN_00179 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOCPNFDN_00180 3.2e-147 K Bacterial transcription activator, effector binding domain
HOCPNFDN_00181 5.9e-118 S Protein of unknown function (DUF554)
HOCPNFDN_00182 1.9e-177 S Alpha/beta hydrolase family
HOCPNFDN_00183 0.0 ydfJ S drug exporters of the RND superfamily
HOCPNFDN_00184 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOCPNFDN_00185 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
HOCPNFDN_00187 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HOCPNFDN_00188 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HOCPNFDN_00189 5.9e-117 ydfE S Flavin reductase like domain
HOCPNFDN_00190 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOCPNFDN_00191 1e-162 ydfC EG EamA-like transporter family
HOCPNFDN_00192 7.2e-149 ydfB J GNAT acetyltransferase
HOCPNFDN_00193 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HOCPNFDN_00194 1.3e-57 arsR K transcriptional
HOCPNFDN_00195 8.4e-105 ydeS K Transcriptional regulator
HOCPNFDN_00196 1.2e-195 ydeR EGP Major facilitator Superfamily
HOCPNFDN_00197 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HOCPNFDN_00198 4.8e-69 ydeP K Transcriptional regulator
HOCPNFDN_00199 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HOCPNFDN_00200 1.1e-58 K HxlR-like helix-turn-helix
HOCPNFDN_00201 8.6e-107 ydeN S Serine hydrolase
HOCPNFDN_00202 4.2e-74 maoC I N-terminal half of MaoC dehydratase
HOCPNFDN_00203 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOCPNFDN_00204 1.8e-153 ydeK EG -transporter
HOCPNFDN_00205 4e-116
HOCPNFDN_00206 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HOCPNFDN_00207 2.9e-47 ydeH
HOCPNFDN_00208 3.4e-220 ydeG EGP Major facilitator superfamily
HOCPNFDN_00209 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOCPNFDN_00210 2.5e-166 ydeE K AraC family transcriptional regulator
HOCPNFDN_00211 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HOCPNFDN_00212 1.1e-166 rhaS5 K AraC-like ligand binding domain
HOCPNFDN_00213 4.6e-35 ydzE EG spore germination
HOCPNFDN_00214 6.1e-79 carD K Transcription factor
HOCPNFDN_00215 8.7e-30 cspL K Cold shock
HOCPNFDN_00216 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HOCPNFDN_00218 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOCPNFDN_00219 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOCPNFDN_00220 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HOCPNFDN_00221 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HOCPNFDN_00223 1.9e-15 yycC K YycC-like protein
HOCPNFDN_00224 8.4e-221 yeaN P COG2807 Cyanate permease
HOCPNFDN_00225 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOCPNFDN_00226 2.2e-73 rplI J binds to the 23S rRNA
HOCPNFDN_00227 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HOCPNFDN_00228 2.9e-160 yybS S membrane
HOCPNFDN_00230 3.9e-84 cotF M Spore coat protein
HOCPNFDN_00231 1.4e-68 ydeP3 K Transcriptional regulator
HOCPNFDN_00232 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HOCPNFDN_00233 1.3e-70
HOCPNFDN_00235 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HOCPNFDN_00236 1e-16
HOCPNFDN_00237 1.3e-78 yybN S Protein of unknown function (DUF2712)
HOCPNFDN_00238 4.1e-125
HOCPNFDN_00239 9e-122
HOCPNFDN_00240 2e-127 S Protein of unknown function (DUF2705)
HOCPNFDN_00241 2.6e-115 V ATPases associated with a variety of cellular activities
HOCPNFDN_00242 6.2e-132
HOCPNFDN_00243 5.9e-67 yybH S SnoaL-like domain
HOCPNFDN_00244 3e-124 yybG S Pentapeptide repeat-containing protein
HOCPNFDN_00245 3.2e-220 ynfM EGP Major facilitator Superfamily
HOCPNFDN_00246 2.1e-165 yybE K Transcriptional regulator
HOCPNFDN_00247 2e-79 yjcF S Acetyltransferase (GNAT) domain
HOCPNFDN_00248 2.7e-77 yybC
HOCPNFDN_00249 3e-127 S Metallo-beta-lactamase superfamily
HOCPNFDN_00250 5.6e-77 yybA 2.3.1.57 K transcriptional
HOCPNFDN_00251 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
HOCPNFDN_00252 1.5e-101 yyaS S Membrane
HOCPNFDN_00253 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
HOCPNFDN_00254 5.4e-67 yyaQ S YjbR
HOCPNFDN_00255 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
HOCPNFDN_00256 1.7e-249 tetL EGP Major facilitator Superfamily
HOCPNFDN_00257 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
HOCPNFDN_00258 5.1e-61 yyaN K MerR HTH family regulatory protein
HOCPNFDN_00259 3.3e-161 yyaM EG EamA-like transporter family
HOCPNFDN_00260 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HOCPNFDN_00261 9.5e-169 yyaK S CAAX protease self-immunity
HOCPNFDN_00262 3.8e-246 EGP Major facilitator superfamily
HOCPNFDN_00263 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HOCPNFDN_00264 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOCPNFDN_00265 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HOCPNFDN_00266 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
HOCPNFDN_00267 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HOCPNFDN_00268 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HOCPNFDN_00269 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HOCPNFDN_00270 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HOCPNFDN_00271 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HOCPNFDN_00272 2.3e-33 yyzM S protein conserved in bacteria
HOCPNFDN_00273 8.1e-177 yyaD S Membrane
HOCPNFDN_00274 1.6e-111 yyaC S Sporulation protein YyaC
HOCPNFDN_00275 2.1e-149 spo0J K Belongs to the ParB family
HOCPNFDN_00276 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HOCPNFDN_00277 1.5e-74 S Bacterial PH domain
HOCPNFDN_00278 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HOCPNFDN_00279 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HOCPNFDN_00280 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HOCPNFDN_00281 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HOCPNFDN_00282 6.5e-108 jag S single-stranded nucleic acid binding R3H
HOCPNFDN_00283 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOCPNFDN_00284 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HOCPNFDN_00285 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HOCPNFDN_00286 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HOCPNFDN_00287 2.4e-33 yaaA S S4 domain
HOCPNFDN_00288 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOCPNFDN_00289 1.8e-37 yaaB S Domain of unknown function (DUF370)
HOCPNFDN_00290 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOCPNFDN_00291 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOCPNFDN_00292 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HOCPNFDN_00293 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HOCPNFDN_00294 1.2e-84 gerD
HOCPNFDN_00295 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HOCPNFDN_00296 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HOCPNFDN_00297 9.7e-66 ybaK S Protein of unknown function (DUF2521)
HOCPNFDN_00298 8.2e-145 ybaJ Q Methyltransferase domain
HOCPNFDN_00299 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HOCPNFDN_00300 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HOCPNFDN_00301 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HOCPNFDN_00302 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOCPNFDN_00303 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOCPNFDN_00304 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOCPNFDN_00305 3.6e-58 rplQ J Ribosomal protein L17
HOCPNFDN_00306 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOCPNFDN_00307 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOCPNFDN_00308 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOCPNFDN_00309 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HOCPNFDN_00310 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOCPNFDN_00311 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HOCPNFDN_00312 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HOCPNFDN_00313 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HOCPNFDN_00314 1.8e-72 rplO J binds to the 23S rRNA
HOCPNFDN_00315 1.9e-23 rpmD J Ribosomal protein L30
HOCPNFDN_00316 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HOCPNFDN_00317 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HOCPNFDN_00318 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOCPNFDN_00319 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HOCPNFDN_00320 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOCPNFDN_00321 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOCPNFDN_00322 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HOCPNFDN_00323 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HOCPNFDN_00324 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOCPNFDN_00325 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HOCPNFDN_00326 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HOCPNFDN_00327 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOCPNFDN_00328 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOCPNFDN_00329 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOCPNFDN_00330 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOCPNFDN_00331 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HOCPNFDN_00332 3e-105 rplD J Forms part of the polypeptide exit tunnel
HOCPNFDN_00333 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOCPNFDN_00334 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HOCPNFDN_00335 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HOCPNFDN_00336 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOCPNFDN_00337 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOCPNFDN_00338 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HOCPNFDN_00339 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HOCPNFDN_00340 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HOCPNFDN_00341 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOCPNFDN_00342 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOCPNFDN_00343 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HOCPNFDN_00344 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HOCPNFDN_00345 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOCPNFDN_00346 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HOCPNFDN_00347 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HOCPNFDN_00348 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HOCPNFDN_00349 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HOCPNFDN_00350 4.4e-115 sigH K Belongs to the sigma-70 factor family
HOCPNFDN_00351 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HOCPNFDN_00352 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOCPNFDN_00353 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HOCPNFDN_00354 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOCPNFDN_00355 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HOCPNFDN_00356 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOCPNFDN_00357 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HOCPNFDN_00358 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HOCPNFDN_00359 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HOCPNFDN_00360 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HOCPNFDN_00361 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOCPNFDN_00362 0.0 clpC O Belongs to the ClpA ClpB family
HOCPNFDN_00363 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HOCPNFDN_00364 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HOCPNFDN_00365 2.9e-76 ctsR K Belongs to the CtsR family
HOCPNFDN_00366 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_00367 0.0 vicK 2.7.13.3 T Histidine kinase
HOCPNFDN_00368 3.6e-260 yycH S protein conserved in bacteria
HOCPNFDN_00369 7.3e-155 yycI S protein conserved in bacteria
HOCPNFDN_00370 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HOCPNFDN_00371 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HOCPNFDN_00372 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HOCPNFDN_00373 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HOCPNFDN_00374 9.7e-261 rocE E amino acid
HOCPNFDN_00375 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HOCPNFDN_00377 5e-188 S aspartate phosphatase
HOCPNFDN_00378 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
HOCPNFDN_00379 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HOCPNFDN_00380 1.6e-221 yycP
HOCPNFDN_00381 2.1e-33 yycQ S Protein of unknown function (DUF2651)
HOCPNFDN_00383 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HOCPNFDN_00384 4.2e-71
HOCPNFDN_00385 1.1e-09 S YyzF-like protein
HOCPNFDN_00386 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOCPNFDN_00387 7.3e-280 S Calcineurin-like phosphoesterase
HOCPNFDN_00388 3.5e-65
HOCPNFDN_00389 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
HOCPNFDN_00390 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HOCPNFDN_00391 8e-12
HOCPNFDN_00392 7.7e-185 S Radical SAM superfamily
HOCPNFDN_00393 8.4e-134 yydH O Peptidase M50
HOCPNFDN_00394 1.8e-110 prrC P ABC transporter
HOCPNFDN_00395 3.3e-119 S ABC-2 family transporter protein
HOCPNFDN_00396 7.6e-13
HOCPNFDN_00397 1.3e-128 yydK K Transcriptional regulator
HOCPNFDN_00398 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HOCPNFDN_00399 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HOCPNFDN_00400 3.8e-287 ahpF O Alkyl hydroperoxide reductase
HOCPNFDN_00401 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HOCPNFDN_00402 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOCPNFDN_00403 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HOCPNFDN_00404 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HOCPNFDN_00405 7.3e-127 gntR K transcriptional
HOCPNFDN_00406 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HOCPNFDN_00407 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
HOCPNFDN_00408 2.6e-118 yxaC M effector of murein hydrolase
HOCPNFDN_00409 5.2e-50 S LrgA family
HOCPNFDN_00410 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HOCPNFDN_00411 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_00412 7.1e-101 yxaF K Transcriptional regulator
HOCPNFDN_00413 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
HOCPNFDN_00414 1.4e-228 P Protein of unknown function (DUF418)
HOCPNFDN_00415 1.1e-75 yxaI S membrane protein domain
HOCPNFDN_00416 3.5e-65 S Family of unknown function (DUF5391)
HOCPNFDN_00417 6.8e-93 S PQQ-like domain
HOCPNFDN_00418 7.6e-214 yxaM U MFS_1 like family
HOCPNFDN_00419 0.0 asnB 6.3.5.4 E Asparagine synthase
HOCPNFDN_00420 1.1e-86 yxnB
HOCPNFDN_00421 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
HOCPNFDN_00422 3.3e-127 yxbB Q Met-10+ like-protein
HOCPNFDN_00423 3.4e-31 csfB S Inhibitor of sigma-G Gin
HOCPNFDN_00424 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HOCPNFDN_00425 4.5e-203 yaaN P Belongs to the TelA family
HOCPNFDN_00426 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HOCPNFDN_00427 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HOCPNFDN_00428 2.2e-54 yaaQ S protein conserved in bacteria
HOCPNFDN_00429 1.5e-71 yaaR S protein conserved in bacteria
HOCPNFDN_00430 2.2e-182 holB 2.7.7.7 L DNA polymerase III
HOCPNFDN_00431 2.1e-146 yaaT S stage 0 sporulation protein
HOCPNFDN_00432 4.8e-31 yabA L Involved in initiation control of chromosome replication
HOCPNFDN_00433 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HOCPNFDN_00434 1.5e-49 yazA L endonuclease containing a URI domain
HOCPNFDN_00435 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOCPNFDN_00436 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HOCPNFDN_00437 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOCPNFDN_00438 1.8e-144 tatD L hydrolase, TatD
HOCPNFDN_00439 4.3e-194 rpfB GH23 T protein conserved in bacteria
HOCPNFDN_00440 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HOCPNFDN_00441 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HOCPNFDN_00442 3.3e-137 yabG S peptidase
HOCPNFDN_00443 7.8e-39 veg S protein conserved in bacteria
HOCPNFDN_00444 8.3e-27 sspF S DNA topological change
HOCPNFDN_00445 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HOCPNFDN_00446 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HOCPNFDN_00447 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HOCPNFDN_00448 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HOCPNFDN_00449 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOCPNFDN_00450 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOCPNFDN_00451 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HOCPNFDN_00452 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HOCPNFDN_00453 2.4e-39 yabK S Peptide ABC transporter permease
HOCPNFDN_00454 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOCPNFDN_00455 1.5e-92 spoVT K stage V sporulation protein
HOCPNFDN_00456 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOCPNFDN_00457 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HOCPNFDN_00458 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HOCPNFDN_00459 1.5e-49 yabP S Sporulation protein YabP
HOCPNFDN_00460 3.9e-108 yabQ S spore cortex biosynthesis protein
HOCPNFDN_00461 1.1e-44 divIC D Septum formation initiator
HOCPNFDN_00462 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HOCPNFDN_00465 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HOCPNFDN_00466 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HOCPNFDN_00467 6.7e-187 KLT serine threonine protein kinase
HOCPNFDN_00468 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HOCPNFDN_00469 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HOCPNFDN_00470 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOCPNFDN_00471 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HOCPNFDN_00472 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HOCPNFDN_00473 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HOCPNFDN_00474 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HOCPNFDN_00475 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOCPNFDN_00476 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HOCPNFDN_00477 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HOCPNFDN_00478 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HOCPNFDN_00479 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HOCPNFDN_00480 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HOCPNFDN_00481 4.1e-30 yazB K transcriptional
HOCPNFDN_00482 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOCPNFDN_00483 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HOCPNFDN_00486 1.9e-211 L Belongs to the 'phage' integrase family
HOCPNFDN_00487 1.3e-90 immA E IrrE N-terminal-like domain
HOCPNFDN_00488 4.3e-62 yvaO K Transcriptional
HOCPNFDN_00489 1.1e-16
HOCPNFDN_00490 8.3e-41
HOCPNFDN_00492 5.1e-63 S Bacterial protein of unknown function (DUF961)
HOCPNFDN_00493 1e-273 ydcQ D Ftsk spoiiie family protein
HOCPNFDN_00494 1.5e-205 nicK L Replication initiation factor
HOCPNFDN_00497 1.2e-32 yddA
HOCPNFDN_00498 1.5e-173 yddB S Conjugative transposon protein TcpC
HOCPNFDN_00499 3e-40 yddC
HOCPNFDN_00500 2.4e-95 yddD S TcpE family
HOCPNFDN_00501 0.0 yddE S AAA-like domain
HOCPNFDN_00502 2e-55 S Domain of unknown function (DUF1874)
HOCPNFDN_00503 0.0 yddG S maturation of SSU-rRNA
HOCPNFDN_00504 2.4e-189 yddH CBM50 M Lysozyme-like
HOCPNFDN_00505 8.7e-87 yddI
HOCPNFDN_00506 4.1e-65 S Domain of unknown function with cystatin-like fold (DUF4467)
HOCPNFDN_00507 9.5e-128 S TIR domain
HOCPNFDN_00508 1.4e-74 S response regulator aspartate phosphatase
HOCPNFDN_00510 3.4e-161
HOCPNFDN_00511 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOCPNFDN_00512 2.4e-71 lrpA K transcriptional
HOCPNFDN_00513 3.9e-78 lrpB K transcriptional
HOCPNFDN_00514 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
HOCPNFDN_00515 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HOCPNFDN_00516 5e-227 ydeG EGP Major facilitator Superfamily
HOCPNFDN_00518 2.7e-182 yaaC S YaaC-like Protein
HOCPNFDN_00519 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HOCPNFDN_00520 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HOCPNFDN_00521 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HOCPNFDN_00522 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HOCPNFDN_00523 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOCPNFDN_00524 1.3e-09
HOCPNFDN_00525 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HOCPNFDN_00526 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HOCPNFDN_00527 5.6e-215 yaaH M Glycoside Hydrolase Family
HOCPNFDN_00528 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
HOCPNFDN_00529 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HOCPNFDN_00530 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOCPNFDN_00531 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HOCPNFDN_00532 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOCPNFDN_00533 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HOCPNFDN_00534 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HOCPNFDN_00535 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCPNFDN_00536 2e-08
HOCPNFDN_00540 2.7e-143 spo0M S COG4326 Sporulation control protein
HOCPNFDN_00541 3e-27
HOCPNFDN_00542 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HOCPNFDN_00543 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HOCPNFDN_00544 1.9e-266 ygaK C Berberine and berberine like
HOCPNFDN_00546 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HOCPNFDN_00547 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HOCPNFDN_00548 1.7e-171 ssuA M Sulfonate ABC transporter
HOCPNFDN_00549 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HOCPNFDN_00550 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HOCPNFDN_00552 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOCPNFDN_00553 4.1e-78 ygaO
HOCPNFDN_00554 4.4e-29 K Transcriptional regulator
HOCPNFDN_00556 7.9e-114 yhzB S B3/4 domain
HOCPNFDN_00557 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HOCPNFDN_00558 4.4e-177 yhbB S Putative amidase domain
HOCPNFDN_00559 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HOCPNFDN_00560 1.2e-109 yhbD K Protein of unknown function (DUF4004)
HOCPNFDN_00561 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HOCPNFDN_00562 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HOCPNFDN_00563 0.0 prkA T Ser protein kinase
HOCPNFDN_00564 2.5e-225 yhbH S Belongs to the UPF0229 family
HOCPNFDN_00565 2.2e-76 yhbI K DNA-binding transcription factor activity
HOCPNFDN_00566 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HOCPNFDN_00567 3.1e-271 yhcA EGP Major facilitator Superfamily
HOCPNFDN_00568 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HOCPNFDN_00569 2.8e-37 yhcC
HOCPNFDN_00570 7.8e-55
HOCPNFDN_00571 6.6e-60 yhcF K Transcriptional regulator
HOCPNFDN_00572 1.6e-123 yhcG V ABC transporter, ATP-binding protein
HOCPNFDN_00573 2.6e-166 yhcH V ABC transporter, ATP-binding protein
HOCPNFDN_00574 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HOCPNFDN_00575 1e-30 cspB K Cold-shock protein
HOCPNFDN_00576 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
HOCPNFDN_00577 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HOCPNFDN_00578 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOCPNFDN_00579 3.7e-44 yhcM
HOCPNFDN_00580 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HOCPNFDN_00581 2.5e-167 yhcP
HOCPNFDN_00582 5.2e-100 yhcQ M Spore coat protein
HOCPNFDN_00583 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HOCPNFDN_00584 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HOCPNFDN_00585 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HOCPNFDN_00586 9.3e-68 yhcU S Family of unknown function (DUF5365)
HOCPNFDN_00587 9.9e-68 yhcV S COG0517 FOG CBS domain
HOCPNFDN_00588 4.6e-120 yhcW 5.4.2.6 S hydrolase
HOCPNFDN_00589 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HOCPNFDN_00590 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOCPNFDN_00591 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HOCPNFDN_00592 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HOCPNFDN_00593 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HOCPNFDN_00594 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HOCPNFDN_00595 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HOCPNFDN_00596 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
HOCPNFDN_00597 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOCPNFDN_00598 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HOCPNFDN_00599 1.2e-38 yhdB S YhdB-like protein
HOCPNFDN_00600 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HOCPNFDN_00601 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HOCPNFDN_00602 3.5e-76 nsrR K Transcriptional regulator
HOCPNFDN_00603 8.7e-239 ygxB M Conserved TM helix
HOCPNFDN_00604 2.1e-276 ycgB S Stage V sporulation protein R
HOCPNFDN_00605 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HOCPNFDN_00606 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HOCPNFDN_00607 3.8e-162 citR K Transcriptional regulator
HOCPNFDN_00608 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
HOCPNFDN_00609 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOCPNFDN_00610 3.4e-250 yhdG E amino acid
HOCPNFDN_00611 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HOCPNFDN_00612 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOCPNFDN_00613 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOCPNFDN_00614 8.1e-45 yhdK S Sigma-M inhibitor protein
HOCPNFDN_00615 6.6e-201 yhdL S Sigma factor regulator N-terminal
HOCPNFDN_00616 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HOCPNFDN_00617 1.5e-191 yhdN C Aldo keto reductase
HOCPNFDN_00618 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HOCPNFDN_00619 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HOCPNFDN_00620 4.1e-74 cueR K transcriptional
HOCPNFDN_00621 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
HOCPNFDN_00622 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HOCPNFDN_00623 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOCPNFDN_00624 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOCPNFDN_00625 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HOCPNFDN_00627 6.6e-204 yhdY M Mechanosensitive ion channel
HOCPNFDN_00628 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HOCPNFDN_00629 1.7e-151 yheN G deacetylase
HOCPNFDN_00630 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HOCPNFDN_00631 2.2e-233 nhaC C Na H antiporter
HOCPNFDN_00632 3.4e-84 nhaX T Belongs to the universal stress protein A family
HOCPNFDN_00633 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HOCPNFDN_00634 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HOCPNFDN_00635 3.7e-111 yheG GM NAD(P)H-binding
HOCPNFDN_00636 6.3e-28 sspB S spore protein
HOCPNFDN_00637 1.3e-36 yheE S Family of unknown function (DUF5342)
HOCPNFDN_00638 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HOCPNFDN_00639 4.3e-216 yheC HJ YheC/D like ATP-grasp
HOCPNFDN_00640 6.7e-204 yheB S Belongs to the UPF0754 family
HOCPNFDN_00641 9.5e-48 yheA S Belongs to the UPF0342 family
HOCPNFDN_00642 3.1e-206 yhaZ L DNA alkylation repair enzyme
HOCPNFDN_00643 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HOCPNFDN_00644 7.1e-294 hemZ H coproporphyrinogen III oxidase
HOCPNFDN_00645 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HOCPNFDN_00646 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HOCPNFDN_00648 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HOCPNFDN_00649 1.1e-26 S YhzD-like protein
HOCPNFDN_00650 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HOCPNFDN_00651 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HOCPNFDN_00652 3.6e-227 yhaO L DNA repair exonuclease
HOCPNFDN_00653 0.0 yhaN L AAA domain
HOCPNFDN_00654 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HOCPNFDN_00655 1.6e-21 yhaL S Sporulation protein YhaL
HOCPNFDN_00656 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HOCPNFDN_00657 8.7e-90 yhaK S Putative zincin peptidase
HOCPNFDN_00658 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HOCPNFDN_00659 1e-113 hpr K Negative regulator of protease production and sporulation
HOCPNFDN_00660 7e-39 yhaH S YtxH-like protein
HOCPNFDN_00661 3.6e-80 trpP S Tryptophan transporter TrpP
HOCPNFDN_00662 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HOCPNFDN_00663 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HOCPNFDN_00664 4.6e-137 ecsA V transporter (ATP-binding protein)
HOCPNFDN_00665 1.8e-215 ecsB U ABC transporter
HOCPNFDN_00666 4.8e-115 ecsC S EcsC protein family
HOCPNFDN_00667 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HOCPNFDN_00668 4.2e-248 yhfA C membrane
HOCPNFDN_00669 7.5e-17 1.15.1.2 C Rubrerythrin
HOCPNFDN_00670 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HOCPNFDN_00671 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HOCPNFDN_00672 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HOCPNFDN_00673 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HOCPNFDN_00674 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HOCPNFDN_00675 1.4e-101 yhgD K Transcriptional regulator
HOCPNFDN_00676 1e-238 yhgE S YhgE Pip N-terminal domain protein
HOCPNFDN_00677 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOCPNFDN_00678 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
HOCPNFDN_00679 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HOCPNFDN_00680 1.7e-72 3.4.13.21 S ASCH
HOCPNFDN_00681 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOCPNFDN_00682 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HOCPNFDN_00683 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
HOCPNFDN_00684 2.6e-112 yhfK GM NmrA-like family
HOCPNFDN_00685 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HOCPNFDN_00686 1.9e-65 yhfM
HOCPNFDN_00687 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
HOCPNFDN_00688 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HOCPNFDN_00689 9.2e-80 VY92_01935 K acetyltransferase
HOCPNFDN_00690 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HOCPNFDN_00691 4.3e-159 yfmC M Periplasmic binding protein
HOCPNFDN_00692 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HOCPNFDN_00693 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
HOCPNFDN_00694 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HOCPNFDN_00695 5e-91 bioY S BioY family
HOCPNFDN_00696 1.7e-182 hemAT NT chemotaxis protein
HOCPNFDN_00697 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HOCPNFDN_00698 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOCPNFDN_00699 1.3e-32 yhzC S IDEAL
HOCPNFDN_00700 4.2e-109 comK K Competence transcription factor
HOCPNFDN_00701 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
HOCPNFDN_00702 7.8e-42 yhjA S Excalibur calcium-binding domain
HOCPNFDN_00703 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOCPNFDN_00704 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HOCPNFDN_00705 5e-60 yhjD
HOCPNFDN_00706 9.1e-110 yhjE S SNARE associated Golgi protein
HOCPNFDN_00707 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HOCPNFDN_00708 1.1e-286 yhjG CH FAD binding domain
HOCPNFDN_00709 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HOCPNFDN_00710 6.9e-215 glcP G Major Facilitator Superfamily
HOCPNFDN_00711 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HOCPNFDN_00712 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HOCPNFDN_00713 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HOCPNFDN_00714 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
HOCPNFDN_00715 3.8e-202 abrB S membrane
HOCPNFDN_00716 3.1e-215 EGP Transmembrane secretion effector
HOCPNFDN_00717 0.0 S Sugar transport-related sRNA regulator N-term
HOCPNFDN_00718 2e-36 yhjQ C COG1145 Ferredoxin
HOCPNFDN_00719 2.2e-78 yhjR S Rubrerythrin
HOCPNFDN_00720 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HOCPNFDN_00721 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HOCPNFDN_00722 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HOCPNFDN_00723 0.0 sbcC L COG0419 ATPase involved in DNA repair
HOCPNFDN_00724 6e-51 yisB V COG1403 Restriction endonuclease
HOCPNFDN_00725 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HOCPNFDN_00726 3e-66 gerPE S Spore germination protein GerPE
HOCPNFDN_00727 6.3e-24 gerPD S Spore germination protein
HOCPNFDN_00728 1.8e-54 gerPC S Spore germination protein
HOCPNFDN_00729 4e-34 gerPB S cell differentiation
HOCPNFDN_00730 1.9e-33 gerPA S Spore germination protein
HOCPNFDN_00731 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HOCPNFDN_00732 1.7e-176 cotH M Spore Coat
HOCPNFDN_00733 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HOCPNFDN_00734 3e-57 yisL S UPF0344 protein
HOCPNFDN_00735 0.0 wprA O Belongs to the peptidase S8 family
HOCPNFDN_00736 7.2e-106 yisN S Protein of unknown function (DUF2777)
HOCPNFDN_00737 0.0 asnO 6.3.5.4 E Asparagine synthase
HOCPNFDN_00738 2.1e-88 yizA S Damage-inducible protein DinB
HOCPNFDN_00739 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HOCPNFDN_00740 4e-243 yisQ V Mate efflux family protein
HOCPNFDN_00741 1.2e-160 yisR K Transcriptional regulator
HOCPNFDN_00742 2.4e-184 purR K helix_turn _helix lactose operon repressor
HOCPNFDN_00743 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HOCPNFDN_00744 1.3e-93 yisT S DinB family
HOCPNFDN_00745 6.4e-108 argO S Lysine exporter protein LysE YggA
HOCPNFDN_00746 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOCPNFDN_00747 4e-36 mcbG S Pentapeptide repeats (9 copies)
HOCPNFDN_00748 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HOCPNFDN_00749 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HOCPNFDN_00750 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HOCPNFDN_00751 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HOCPNFDN_00752 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
HOCPNFDN_00753 1.9e-141 yitD 4.4.1.19 S synthase
HOCPNFDN_00754 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOCPNFDN_00755 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HOCPNFDN_00756 4e-229 yitG EGP Major facilitator Superfamily
HOCPNFDN_00757 1.8e-161 yitH K Acetyltransferase (GNAT) domain
HOCPNFDN_00758 2e-82 yjcF S Acetyltransferase (GNAT) domain
HOCPNFDN_00759 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HOCPNFDN_00760 8.6e-55 yajQ S Belongs to the UPF0234 family
HOCPNFDN_00761 4e-161 cvfB S protein conserved in bacteria
HOCPNFDN_00762 8.5e-94
HOCPNFDN_00763 2.8e-171
HOCPNFDN_00764 1.5e-97 S Sporulation delaying protein SdpA
HOCPNFDN_00765 1.5e-58 K Transcriptional regulator PadR-like family
HOCPNFDN_00766 2e-95
HOCPNFDN_00767 1.4e-44 yitR S Domain of unknown function (DUF3784)
HOCPNFDN_00768 2.2e-311 nprB 3.4.24.28 E Peptidase M4
HOCPNFDN_00769 8.4e-159 yitS S protein conserved in bacteria
HOCPNFDN_00770 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HOCPNFDN_00771 1.9e-72 ipi S Intracellular proteinase inhibitor
HOCPNFDN_00772 1.2e-17 S Protein of unknown function (DUF3813)
HOCPNFDN_00773 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HOCPNFDN_00774 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HOCPNFDN_00775 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HOCPNFDN_00776 1.5e-22 pilT S Proteolipid membrane potential modulator
HOCPNFDN_00777 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
HOCPNFDN_00778 1.7e-88 norB G Major Facilitator Superfamily
HOCPNFDN_00779 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HOCPNFDN_00780 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HOCPNFDN_00781 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HOCPNFDN_00782 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HOCPNFDN_00783 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HOCPNFDN_00784 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HOCPNFDN_00785 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HOCPNFDN_00786 9.5e-28 yjzC S YjzC-like protein
HOCPNFDN_00787 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HOCPNFDN_00788 6.2e-142 yjaU I carboxylic ester hydrolase activity
HOCPNFDN_00789 7.3e-103 yjaV
HOCPNFDN_00790 1.1e-183 med S Transcriptional activator protein med
HOCPNFDN_00791 7.3e-26 comZ S ComZ
HOCPNFDN_00792 2.7e-22 yjzB
HOCPNFDN_00793 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOCPNFDN_00794 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HOCPNFDN_00795 7.8e-151 yjaZ O Zn-dependent protease
HOCPNFDN_00796 1.8e-184 appD P Belongs to the ABC transporter superfamily
HOCPNFDN_00797 6.5e-187 appF E Belongs to the ABC transporter superfamily
HOCPNFDN_00798 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HOCPNFDN_00799 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCPNFDN_00800 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCPNFDN_00801 5e-147 yjbA S Belongs to the UPF0736 family
HOCPNFDN_00802 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HOCPNFDN_00803 0.0 oppA E ABC transporter substrate-binding protein
HOCPNFDN_00804 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCPNFDN_00805 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCPNFDN_00806 3e-198 oppD P Belongs to the ABC transporter superfamily
HOCPNFDN_00807 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HOCPNFDN_00808 8.6e-196 yjbB EGP Major Facilitator Superfamily
HOCPNFDN_00809 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOCPNFDN_00810 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HOCPNFDN_00811 6e-112 yjbE P Integral membrane protein TerC family
HOCPNFDN_00812 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HOCPNFDN_00813 2.3e-223 yjbF S Competence protein
HOCPNFDN_00814 0.0 pepF E oligoendopeptidase F
HOCPNFDN_00815 1.8e-20
HOCPNFDN_00817 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HOCPNFDN_00818 3.7e-72 yjbI S Bacterial-like globin
HOCPNFDN_00819 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HOCPNFDN_00820 2.4e-101 yjbK S protein conserved in bacteria
HOCPNFDN_00821 7.1e-62 yjbL S Belongs to the UPF0738 family
HOCPNFDN_00822 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HOCPNFDN_00823 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOCPNFDN_00824 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HOCPNFDN_00825 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HOCPNFDN_00826 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HOCPNFDN_00827 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HOCPNFDN_00828 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HOCPNFDN_00829 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
HOCPNFDN_00830 3e-30 thiS H thiamine diphosphate biosynthetic process
HOCPNFDN_00831 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HOCPNFDN_00832 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HOCPNFDN_00833 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HOCPNFDN_00834 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HOCPNFDN_00835 5.9e-54 yjbX S Spore coat protein
HOCPNFDN_00836 5.2e-83 cotZ S Spore coat protein
HOCPNFDN_00837 3.4e-96 cotY S Spore coat protein Z
HOCPNFDN_00838 6.4e-77 cotX S Spore Coat Protein X and V domain
HOCPNFDN_00839 3e-32 cotW
HOCPNFDN_00840 2.3e-55 cotV S Spore Coat Protein X and V domain
HOCPNFDN_00841 8.7e-57 yjcA S Protein of unknown function (DUF1360)
HOCPNFDN_00844 2.9e-38 spoVIF S Stage VI sporulation protein F
HOCPNFDN_00845 0.0 yjcD 3.6.4.12 L DNA helicase
HOCPNFDN_00846 1.7e-38
HOCPNFDN_00847 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOCPNFDN_00848 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HOCPNFDN_00849 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
HOCPNFDN_00850 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HOCPNFDN_00851 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HOCPNFDN_00852 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
HOCPNFDN_00853 1.1e-212 yjcL S Protein of unknown function (DUF819)
HOCPNFDN_00856 2.1e-190 S Putative amidase domain
HOCPNFDN_00857 2.6e-44 yjcN
HOCPNFDN_00860 8.5e-81 L Transposase
HOCPNFDN_00861 1.6e-72 yjcP
HOCPNFDN_00862 4.1e-49 S YjcQ protein
HOCPNFDN_00863 1.1e-92 yqaS L DNA packaging
HOCPNFDN_00864 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
HOCPNFDN_00865 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
HOCPNFDN_00867 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HOCPNFDN_00868 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HOCPNFDN_00869 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HOCPNFDN_00870 4.8e-51 yjdF S Protein of unknown function (DUF2992)
HOCPNFDN_00871 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HOCPNFDN_00873 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOCPNFDN_00874 4.2e-29 S Domain of unknown function (DUF4177)
HOCPNFDN_00875 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HOCPNFDN_00876 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HOCPNFDN_00878 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HOCPNFDN_00879 5.5e-83 S Protein of unknown function (DUF2690)
HOCPNFDN_00880 3.6e-21 yjfB S Putative motility protein
HOCPNFDN_00881 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
HOCPNFDN_00882 1.2e-45 T PhoQ Sensor
HOCPNFDN_00883 8.9e-104 yjgB S Domain of unknown function (DUF4309)
HOCPNFDN_00884 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HOCPNFDN_00885 4.3e-95 yjgD S Protein of unknown function (DUF1641)
HOCPNFDN_00886 8.7e-07 S Domain of unknown function (DUF4352)
HOCPNFDN_00887 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HOCPNFDN_00889 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HOCPNFDN_00890 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HOCPNFDN_00891 8.2e-30
HOCPNFDN_00892 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HOCPNFDN_00893 1.9e-122 ybbM S transport system, permease component
HOCPNFDN_00894 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HOCPNFDN_00895 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
HOCPNFDN_00896 2.8e-93 yjlB S Cupin domain
HOCPNFDN_00897 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HOCPNFDN_00898 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HOCPNFDN_00899 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
HOCPNFDN_00900 5.8e-250 yjmB G symporter YjmB
HOCPNFDN_00901 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HOCPNFDN_00902 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HOCPNFDN_00903 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HOCPNFDN_00904 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_00905 3.7e-227 exuT G Sugar (and other) transporter
HOCPNFDN_00906 2.3e-184 exuR K transcriptional
HOCPNFDN_00907 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HOCPNFDN_00908 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HOCPNFDN_00909 4.3e-130 MA20_18170 S membrane transporter protein
HOCPNFDN_00910 3.3e-80 yjoA S DinB family
HOCPNFDN_00911 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HOCPNFDN_00912 2.1e-213 S response regulator aspartate phosphatase
HOCPNFDN_00914 6.3e-41 S YCII-related domain
HOCPNFDN_00915 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HOCPNFDN_00916 2.1e-61 yjqA S Bacterial PH domain
HOCPNFDN_00917 4.2e-112 yjqB S Pfam:DUF867
HOCPNFDN_00918 4.4e-160 ydbD P Catalase
HOCPNFDN_00919 1.6e-111 xkdA E IrrE N-terminal-like domain
HOCPNFDN_00920 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HOCPNFDN_00922 5.9e-157 xkdB K sequence-specific DNA binding
HOCPNFDN_00923 6.4e-119 xkdC L Bacterial dnaA protein
HOCPNFDN_00926 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HOCPNFDN_00927 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HOCPNFDN_00928 4.8e-140 xtmA L phage terminase small subunit
HOCPNFDN_00929 9.6e-255 xtmB S phage terminase, large subunit
HOCPNFDN_00930 5.4e-286 yqbA S portal protein
HOCPNFDN_00931 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HOCPNFDN_00932 5.8e-169 xkdG S Phage capsid family
HOCPNFDN_00933 5.5e-65 yqbG S Protein of unknown function (DUF3199)
HOCPNFDN_00934 8.7e-65 yqbH S Domain of unknown function (DUF3599)
HOCPNFDN_00935 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HOCPNFDN_00936 1.9e-77 xkdJ
HOCPNFDN_00937 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HOCPNFDN_00938 6.1e-76 xkdM S Phage tail tube protein
HOCPNFDN_00939 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HOCPNFDN_00940 0.0 xkdO L Transglycosylase SLT domain
HOCPNFDN_00941 3.7e-122 xkdP S Lysin motif
HOCPNFDN_00942 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HOCPNFDN_00943 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HOCPNFDN_00944 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HOCPNFDN_00945 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HOCPNFDN_00946 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HOCPNFDN_00947 6.7e-41
HOCPNFDN_00948 0.0
HOCPNFDN_00949 2.6e-55 xkdW S XkdW protein
HOCPNFDN_00950 1.7e-23 xkdX
HOCPNFDN_00951 1.2e-154 xepA
HOCPNFDN_00952 2.8e-39 xhlA S Haemolysin XhlA
HOCPNFDN_00953 9.3e-40 xhlB S SPP1 phage holin
HOCPNFDN_00954 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HOCPNFDN_00955 6.7e-23 spoIISB S Stage II sporulation protein SB
HOCPNFDN_00956 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HOCPNFDN_00957 5.8e-175 pit P phosphate transporter
HOCPNFDN_00958 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HOCPNFDN_00959 9.4e-242 steT E amino acid
HOCPNFDN_00960 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HOCPNFDN_00962 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOCPNFDN_00963 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HOCPNFDN_00965 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HOCPNFDN_00966 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HOCPNFDN_00967 7.9e-154 dppA E D-aminopeptidase
HOCPNFDN_00968 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCPNFDN_00969 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOCPNFDN_00970 3.4e-191 dppD P Belongs to the ABC transporter superfamily
HOCPNFDN_00971 0.0 dppE E ABC transporter substrate-binding protein
HOCPNFDN_00973 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HOCPNFDN_00974 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HOCPNFDN_00975 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HOCPNFDN_00976 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
HOCPNFDN_00977 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
HOCPNFDN_00978 5.3e-161 ykgA E Amidinotransferase
HOCPNFDN_00979 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HOCPNFDN_00980 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HOCPNFDN_00981 1e-07
HOCPNFDN_00982 5.4e-130 ykjA S Protein of unknown function (DUF421)
HOCPNFDN_00983 1e-98 ykkA S Protein of unknown function (DUF664)
HOCPNFDN_00984 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HOCPNFDN_00985 3.5e-55 ykkC P Multidrug resistance protein
HOCPNFDN_00986 1.1e-50 ykkD P Multidrug resistance protein
HOCPNFDN_00987 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HOCPNFDN_00988 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOCPNFDN_00989 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HOCPNFDN_00990 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HOCPNFDN_00991 3.9e-75 ohrR K COG1846 Transcriptional regulators
HOCPNFDN_00992 8.4e-72 ohrB O Organic hydroperoxide resistance protein
HOCPNFDN_00994 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HOCPNFDN_00995 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HOCPNFDN_00996 1.7e-176 isp O Belongs to the peptidase S8 family
HOCPNFDN_00997 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HOCPNFDN_00998 1.8e-136 ykoC P Cobalt transport protein
HOCPNFDN_00999 4.6e-311 P ABC transporter, ATP-binding protein
HOCPNFDN_01000 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HOCPNFDN_01001 7.9e-111 ykoF S YKOF-related Family
HOCPNFDN_01002 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_01003 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
HOCPNFDN_01004 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
HOCPNFDN_01005 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
HOCPNFDN_01008 2.2e-222 mgtE P Acts as a magnesium transporter
HOCPNFDN_01009 1.4e-53 tnrA K transcriptional
HOCPNFDN_01010 5.9e-18
HOCPNFDN_01011 6.9e-26 ykoL
HOCPNFDN_01012 1.3e-81 mhqR K transcriptional
HOCPNFDN_01013 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HOCPNFDN_01014 3.7e-99 ykoP G polysaccharide deacetylase
HOCPNFDN_01015 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HOCPNFDN_01016 0.0 ykoS
HOCPNFDN_01017 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HOCPNFDN_01018 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HOCPNFDN_01019 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HOCPNFDN_01020 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HOCPNFDN_01021 1.4e-116 ykoX S membrane-associated protein
HOCPNFDN_01022 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HOCPNFDN_01023 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOCPNFDN_01024 8.2e-117 rsgI S Anti-sigma factor N-terminus
HOCPNFDN_01025 1.9e-26 sspD S small acid-soluble spore protein
HOCPNFDN_01026 1.5e-124 ykrK S Domain of unknown function (DUF1836)
HOCPNFDN_01027 7e-156 htpX O Belongs to the peptidase M48B family
HOCPNFDN_01028 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HOCPNFDN_01029 1.2e-10 ydfR S Protein of unknown function (DUF421)
HOCPNFDN_01030 4.5e-22 ykzE
HOCPNFDN_01031 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HOCPNFDN_01032 0.0 kinE 2.7.13.3 T Histidine kinase
HOCPNFDN_01033 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HOCPNFDN_01035 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HOCPNFDN_01036 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HOCPNFDN_01037 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HOCPNFDN_01038 8e-232 mtnE 2.6.1.83 E Aminotransferase
HOCPNFDN_01039 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HOCPNFDN_01040 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HOCPNFDN_01041 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HOCPNFDN_01042 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HOCPNFDN_01043 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HOCPNFDN_01044 6.4e-09 S Spo0E like sporulation regulatory protein
HOCPNFDN_01045 1.4e-64 eag
HOCPNFDN_01046 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HOCPNFDN_01047 1.3e-75 ykvE K transcriptional
HOCPNFDN_01048 2.5e-125 motB N Flagellar motor protein
HOCPNFDN_01049 2.7e-138 motA N flagellar motor
HOCPNFDN_01050 0.0 clpE O Belongs to the ClpA ClpB family
HOCPNFDN_01051 8.7e-182 ykvI S membrane
HOCPNFDN_01052 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HOCPNFDN_01053 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HOCPNFDN_01054 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HOCPNFDN_01055 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HOCPNFDN_01056 2e-61 ykvN K Transcriptional regulator
HOCPNFDN_01057 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
HOCPNFDN_01058 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
HOCPNFDN_01059 1.2e-35 3.5.1.104 M LysM domain
HOCPNFDN_01060 8.5e-133 G Glycosyl hydrolases family 18
HOCPNFDN_01061 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HOCPNFDN_01062 6e-25 ykvS S protein conserved in bacteria
HOCPNFDN_01063 2.8e-28
HOCPNFDN_01064 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
HOCPNFDN_01065 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOCPNFDN_01066 4.9e-90 stoA CO thiol-disulfide
HOCPNFDN_01067 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HOCPNFDN_01068 3.8e-09
HOCPNFDN_01069 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HOCPNFDN_01071 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
HOCPNFDN_01073 4.5e-128 glcT K antiterminator
HOCPNFDN_01074 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOCPNFDN_01075 2.1e-39 ptsH G phosphocarrier protein HPr
HOCPNFDN_01076 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOCPNFDN_01077 7.2e-39 splA S Transcriptional regulator
HOCPNFDN_01078 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
HOCPNFDN_01079 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOCPNFDN_01080 2e-264 mcpC NT chemotaxis protein
HOCPNFDN_01081 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HOCPNFDN_01082 8e-124 ykwD J protein with SCP PR1 domains
HOCPNFDN_01083 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HOCPNFDN_01084 0.0 pilS 2.7.13.3 T Histidine kinase
HOCPNFDN_01085 8e-224 patA 2.6.1.1 E Aminotransferase
HOCPNFDN_01086 2.2e-15
HOCPNFDN_01087 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HOCPNFDN_01088 1.7e-84 ykyB S YkyB-like protein
HOCPNFDN_01089 1.6e-238 ykuC EGP Major facilitator Superfamily
HOCPNFDN_01090 4.6e-88 ykuD S protein conserved in bacteria
HOCPNFDN_01091 9.4e-166 ykuE S Metallophosphoesterase
HOCPNFDN_01092 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOCPNFDN_01093 0.0 3.2.1.132 M Putative peptidoglycan binding domain
HOCPNFDN_01094 1.7e-93 M Peptidoglycan-binding domain 1 protein
HOCPNFDN_01096 5.2e-234 ykuI T Diguanylate phosphodiesterase
HOCPNFDN_01097 3.9e-37 ykuJ S protein conserved in bacteria
HOCPNFDN_01098 4.4e-94 ykuK S Ribonuclease H-like
HOCPNFDN_01099 3.9e-27 ykzF S Antirepressor AbbA
HOCPNFDN_01100 1.6e-76 ykuL S CBS domain
HOCPNFDN_01101 3.5e-168 ccpC K Transcriptional regulator
HOCPNFDN_01102 5.7e-88 fld C Flavodoxin domain
HOCPNFDN_01103 3.2e-177 ykuO
HOCPNFDN_01104 3.2e-80 fld C Flavodoxin
HOCPNFDN_01105 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HOCPNFDN_01106 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HOCPNFDN_01107 9e-37 ykuS S Belongs to the UPF0180 family
HOCPNFDN_01108 8.8e-142 ykuT M Mechanosensitive ion channel
HOCPNFDN_01109 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HOCPNFDN_01110 4.4e-82 ykuV CO thiol-disulfide
HOCPNFDN_01111 5.8e-95 rok K Repressor of ComK
HOCPNFDN_01112 2.9e-147 yknT
HOCPNFDN_01113 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HOCPNFDN_01114 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HOCPNFDN_01115 8.1e-246 moeA 2.10.1.1 H molybdopterin
HOCPNFDN_01116 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HOCPNFDN_01117 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HOCPNFDN_01118 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HOCPNFDN_01119 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HOCPNFDN_01120 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HOCPNFDN_01121 1e-117 yknW S Yip1 domain
HOCPNFDN_01122 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOCPNFDN_01123 2.5e-124 macB V ABC transporter, ATP-binding protein
HOCPNFDN_01124 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HOCPNFDN_01125 3.1e-136 fruR K Transcriptional regulator
HOCPNFDN_01126 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HOCPNFDN_01127 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HOCPNFDN_01128 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HOCPNFDN_01129 8.1e-39 ykoA
HOCPNFDN_01130 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HOCPNFDN_01131 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HOCPNFDN_01132 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HOCPNFDN_01133 1.1e-12 S Uncharacterized protein YkpC
HOCPNFDN_01134 7.7e-183 mreB D Rod-share determining protein MreBH
HOCPNFDN_01135 1.5e-43 abrB K of stationary sporulation gene expression
HOCPNFDN_01136 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HOCPNFDN_01137 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HOCPNFDN_01138 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HOCPNFDN_01139 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HOCPNFDN_01140 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOCPNFDN_01141 8.2e-31 ykzG S Belongs to the UPF0356 family
HOCPNFDN_01142 1.4e-147 ykrA S hydrolases of the HAD superfamily
HOCPNFDN_01143 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOCPNFDN_01145 2e-115 recN L Putative cell-wall binding lipoprotein
HOCPNFDN_01146 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HOCPNFDN_01147 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HOCPNFDN_01148 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HOCPNFDN_01149 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HOCPNFDN_01150 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HOCPNFDN_01151 3.5e-277 speA 4.1.1.19 E Arginine
HOCPNFDN_01152 1.6e-42 yktA S Belongs to the UPF0223 family
HOCPNFDN_01153 7.1e-118 yktB S Belongs to the UPF0637 family
HOCPNFDN_01154 7.1e-26 ykzI
HOCPNFDN_01155 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HOCPNFDN_01156 6.9e-78 ykzC S Acetyltransferase (GNAT) family
HOCPNFDN_01157 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HOCPNFDN_01158 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HOCPNFDN_01159 0.0 ylaA
HOCPNFDN_01160 2.7e-42 ylaB
HOCPNFDN_01161 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HOCPNFDN_01162 1.2e-11 sigC S Putative zinc-finger
HOCPNFDN_01163 1.8e-38 ylaE
HOCPNFDN_01164 8.2e-22 S Family of unknown function (DUF5325)
HOCPNFDN_01165 0.0 typA T GTP-binding protein TypA
HOCPNFDN_01166 4.2e-47 ylaH S YlaH-like protein
HOCPNFDN_01167 2.5e-32 ylaI S protein conserved in bacteria
HOCPNFDN_01168 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HOCPNFDN_01169 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HOCPNFDN_01170 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HOCPNFDN_01171 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HOCPNFDN_01172 8.7e-44 ylaN S Belongs to the UPF0358 family
HOCPNFDN_01173 4.5e-214 ftsW D Belongs to the SEDS family
HOCPNFDN_01174 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HOCPNFDN_01175 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HOCPNFDN_01176 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HOCPNFDN_01177 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HOCPNFDN_01178 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HOCPNFDN_01179 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HOCPNFDN_01180 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HOCPNFDN_01181 3e-167 ctaG S cytochrome c oxidase
HOCPNFDN_01182 7e-62 ylbA S YugN-like family
HOCPNFDN_01183 2.6e-74 ylbB T COG0517 FOG CBS domain
HOCPNFDN_01184 3e-201 ylbC S protein with SCP PR1 domains
HOCPNFDN_01185 4.1e-63 ylbD S Putative coat protein
HOCPNFDN_01186 6.7e-37 ylbE S YlbE-like protein
HOCPNFDN_01187 1.8e-75 ylbF S Belongs to the UPF0342 family
HOCPNFDN_01188 7.5e-39 ylbG S UPF0298 protein
HOCPNFDN_01189 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
HOCPNFDN_01190 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOCPNFDN_01191 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
HOCPNFDN_01192 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HOCPNFDN_01193 6.8e-187 ylbL T Belongs to the peptidase S16 family
HOCPNFDN_01194 2.8e-235 ylbM S Belongs to the UPF0348 family
HOCPNFDN_01196 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HOCPNFDN_01197 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HOCPNFDN_01198 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HOCPNFDN_01199 4e-89 ylbP K n-acetyltransferase
HOCPNFDN_01200 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HOCPNFDN_01201 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HOCPNFDN_01202 2.9e-78 mraZ K Belongs to the MraZ family
HOCPNFDN_01203 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HOCPNFDN_01204 3.7e-44 ftsL D Essential cell division protein
HOCPNFDN_01205 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HOCPNFDN_01206 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HOCPNFDN_01207 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOCPNFDN_01208 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOCPNFDN_01209 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HOCPNFDN_01210 5.7e-186 spoVE D Belongs to the SEDS family
HOCPNFDN_01211 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HOCPNFDN_01212 5.3e-167 murB 1.3.1.98 M cell wall formation
HOCPNFDN_01213 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HOCPNFDN_01214 2.4e-103 ylxW S protein conserved in bacteria
HOCPNFDN_01215 1e-102 ylxX S protein conserved in bacteria
HOCPNFDN_01216 6.2e-58 sbp S small basic protein
HOCPNFDN_01217 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HOCPNFDN_01218 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOCPNFDN_01219 0.0 bpr O COG1404 Subtilisin-like serine proteases
HOCPNFDN_01220 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HOCPNFDN_01221 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOCPNFDN_01222 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOCPNFDN_01223 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HOCPNFDN_01224 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
HOCPNFDN_01225 2.4e-37 ylmC S sporulation protein
HOCPNFDN_01226 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HOCPNFDN_01227 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HOCPNFDN_01228 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HOCPNFDN_01229 1.3e-39 yggT S membrane
HOCPNFDN_01230 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HOCPNFDN_01231 2.6e-67 divIVA D Cell division initiation protein
HOCPNFDN_01232 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HOCPNFDN_01233 1.3e-63 dksA T COG1734 DnaK suppressor protein
HOCPNFDN_01234 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HOCPNFDN_01235 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HOCPNFDN_01236 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HOCPNFDN_01237 9e-232 pyrP F Xanthine uracil
HOCPNFDN_01238 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HOCPNFDN_01239 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HOCPNFDN_01240 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HOCPNFDN_01241 0.0 carB 6.3.5.5 F Belongs to the CarB family
HOCPNFDN_01242 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HOCPNFDN_01243 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HOCPNFDN_01244 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HOCPNFDN_01245 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOCPNFDN_01247 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HOCPNFDN_01248 1.1e-179 cysP P phosphate transporter
HOCPNFDN_01249 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HOCPNFDN_01250 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HOCPNFDN_01251 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HOCPNFDN_01252 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HOCPNFDN_01253 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HOCPNFDN_01254 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HOCPNFDN_01255 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HOCPNFDN_01256 2.4e-156 yloC S stress-induced protein
HOCPNFDN_01257 1.5e-40 ylzA S Belongs to the UPF0296 family
HOCPNFDN_01258 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HOCPNFDN_01259 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HOCPNFDN_01260 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HOCPNFDN_01261 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOCPNFDN_01262 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOCPNFDN_01263 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOCPNFDN_01264 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HOCPNFDN_01265 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HOCPNFDN_01266 2.4e-141 stp 3.1.3.16 T phosphatase
HOCPNFDN_01267 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HOCPNFDN_01268 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HOCPNFDN_01269 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HOCPNFDN_01270 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HOCPNFDN_01271 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HOCPNFDN_01272 5.5e-59 asp S protein conserved in bacteria
HOCPNFDN_01273 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
HOCPNFDN_01274 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HOCPNFDN_01275 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HOCPNFDN_01276 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HOCPNFDN_01277 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HOCPNFDN_01278 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HOCPNFDN_01279 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HOCPNFDN_01280 6.1e-129 IQ reductase
HOCPNFDN_01281 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOCPNFDN_01282 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HOCPNFDN_01283 0.0 smc D Required for chromosome condensation and partitioning
HOCPNFDN_01284 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HOCPNFDN_01285 2.9e-87
HOCPNFDN_01286 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HOCPNFDN_01287 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOCPNFDN_01288 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HOCPNFDN_01289 1.2e-36 ylqC S Belongs to the UPF0109 family
HOCPNFDN_01290 1.3e-61 ylqD S YlqD protein
HOCPNFDN_01291 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOCPNFDN_01292 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HOCPNFDN_01293 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HOCPNFDN_01294 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HOCPNFDN_01295 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOCPNFDN_01296 8.5e-291 ylqG
HOCPNFDN_01297 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HOCPNFDN_01298 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HOCPNFDN_01299 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HOCPNFDN_01300 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HOCPNFDN_01301 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOCPNFDN_01302 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HOCPNFDN_01303 2.5e-169 xerC L tyrosine recombinase XerC
HOCPNFDN_01304 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HOCPNFDN_01305 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HOCPNFDN_01306 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HOCPNFDN_01307 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HOCPNFDN_01308 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
HOCPNFDN_01309 1.9e-31 fliE N Flagellar hook-basal body
HOCPNFDN_01310 7.2e-29 fliF N The M ring may be actively involved in energy transduction
HOCPNFDN_01311 8.5e-217 fliF N The M ring may be actively involved in energy transduction
HOCPNFDN_01312 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HOCPNFDN_01313 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HOCPNFDN_01314 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HOCPNFDN_01315 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HOCPNFDN_01316 7.7e-37 ylxF S MgtE intracellular N domain
HOCPNFDN_01317 1.2e-221 fliK N Flagellar hook-length control protein
HOCPNFDN_01318 1.7e-72 flgD N Flagellar basal body rod modification protein
HOCPNFDN_01319 8.2e-140 flgG N Flagellar basal body rod
HOCPNFDN_01320 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HOCPNFDN_01321 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HOCPNFDN_01322 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HOCPNFDN_01323 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HOCPNFDN_01324 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
HOCPNFDN_01325 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HOCPNFDN_01326 2.2e-36 fliQ N Role in flagellar biosynthesis
HOCPNFDN_01327 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HOCPNFDN_01328 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HOCPNFDN_01329 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HOCPNFDN_01330 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
HOCPNFDN_01331 7.5e-158 flhG D Belongs to the ParA family
HOCPNFDN_01332 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HOCPNFDN_01333 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HOCPNFDN_01334 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HOCPNFDN_01335 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HOCPNFDN_01336 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HOCPNFDN_01337 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOCPNFDN_01338 4.3e-78 ylxL
HOCPNFDN_01339 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HOCPNFDN_01340 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HOCPNFDN_01341 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HOCPNFDN_01342 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HOCPNFDN_01343 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOCPNFDN_01344 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HOCPNFDN_01345 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HOCPNFDN_01346 7.7e-233 rasP M zinc metalloprotease
HOCPNFDN_01347 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HOCPNFDN_01348 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOCPNFDN_01349 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HOCPNFDN_01350 1.1e-203 nusA K Participates in both transcription termination and antitermination
HOCPNFDN_01351 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HOCPNFDN_01352 3.1e-47 ylxQ J ribosomal protein
HOCPNFDN_01353 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HOCPNFDN_01354 3e-44 ylxP S protein conserved in bacteria
HOCPNFDN_01355 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HOCPNFDN_01356 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HOCPNFDN_01357 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HOCPNFDN_01358 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HOCPNFDN_01359 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HOCPNFDN_01360 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HOCPNFDN_01361 4.4e-233 pepR S Belongs to the peptidase M16 family
HOCPNFDN_01362 2.6e-42 ymxH S YlmC YmxH family
HOCPNFDN_01363 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HOCPNFDN_01364 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HOCPNFDN_01365 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOCPNFDN_01366 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HOCPNFDN_01367 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOCPNFDN_01368 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOCPNFDN_01369 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HOCPNFDN_01370 4.4e-32 S YlzJ-like protein
HOCPNFDN_01371 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HOCPNFDN_01372 1.4e-133 ymfC K Transcriptional regulator
HOCPNFDN_01373 1.5e-206 ymfD EGP Major facilitator Superfamily
HOCPNFDN_01374 2.6e-236 ymfF S Peptidase M16
HOCPNFDN_01375 1.4e-242 ymfH S zinc protease
HOCPNFDN_01376 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HOCPNFDN_01377 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HOCPNFDN_01378 1.8e-142 ymfK S Protein of unknown function (DUF3388)
HOCPNFDN_01379 1.9e-124 ymfM S protein conserved in bacteria
HOCPNFDN_01380 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOCPNFDN_01381 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
HOCPNFDN_01382 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOCPNFDN_01383 1e-215 pbpX V Beta-lactamase
HOCPNFDN_01384 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HOCPNFDN_01385 1.9e-152 ymdB S protein conserved in bacteria
HOCPNFDN_01386 1.2e-36 spoVS S Stage V sporulation protein S
HOCPNFDN_01387 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HOCPNFDN_01388 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HOCPNFDN_01389 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HOCPNFDN_01390 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HOCPNFDN_01391 2.2e-88 cotE S Spore coat protein
HOCPNFDN_01392 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HOCPNFDN_01393 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HOCPNFDN_01394 2.3e-70 S Regulatory protein YrvL
HOCPNFDN_01396 1.2e-97 ymcC S Membrane
HOCPNFDN_01397 4.4e-109 pksA K Transcriptional regulator
HOCPNFDN_01398 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HOCPNFDN_01399 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HOCPNFDN_01400 2.4e-186 pksD Q Acyl transferase domain
HOCPNFDN_01401 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HOCPNFDN_01402 1.4e-37 acpK IQ Phosphopantetheine attachment site
HOCPNFDN_01403 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HOCPNFDN_01404 1.3e-245 pksG 2.3.3.10 I synthase
HOCPNFDN_01405 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
HOCPNFDN_01406 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HOCPNFDN_01407 0.0 rhiB IQ polyketide synthase
HOCPNFDN_01408 0.0 pfaA Q Polyketide synthase of type I
HOCPNFDN_01409 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HOCPNFDN_01410 0.0 dhbF IQ polyketide synthase
HOCPNFDN_01411 0.0 pks13 HQ Beta-ketoacyl synthase
HOCPNFDN_01412 2.5e-233 cypA C Cytochrome P450
HOCPNFDN_01413 1.2e-61 ymzB
HOCPNFDN_01414 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
HOCPNFDN_01415 4.6e-252 aprX O Belongs to the peptidase S8 family
HOCPNFDN_01416 2.1e-126 ymaC S Replication protein
HOCPNFDN_01417 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
HOCPNFDN_01418 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HOCPNFDN_01419 4.9e-51 ebrA P Small Multidrug Resistance protein
HOCPNFDN_01421 2.1e-46 ymaF S YmaF family
HOCPNFDN_01422 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HOCPNFDN_01423 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HOCPNFDN_01424 6.3e-23
HOCPNFDN_01425 4.5e-22 ymzA
HOCPNFDN_01426 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HOCPNFDN_01427 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOCPNFDN_01428 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOCPNFDN_01429 2e-109 ymaB
HOCPNFDN_01430 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HOCPNFDN_01431 1.7e-176 spoVK O stage V sporulation protein K
HOCPNFDN_01432 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HOCPNFDN_01433 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HOCPNFDN_01434 1.1e-68 glnR K transcriptional
HOCPNFDN_01435 7e-261 glnA 6.3.1.2 E glutamine synthetase
HOCPNFDN_01436 5e-10
HOCPNFDN_01437 2.5e-32
HOCPNFDN_01438 5.8e-39
HOCPNFDN_01439 6.8e-80 G regulation of fungal-type cell wall biogenesis
HOCPNFDN_01440 4.9e-145 ynaC
HOCPNFDN_01441 2e-99 ynaD J Acetyltransferase (GNAT) domain
HOCPNFDN_01442 1.9e-123 ynaE S Domain of unknown function (DUF3885)
HOCPNFDN_01443 6.4e-60 ynaF
HOCPNFDN_01446 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HOCPNFDN_01447 2.7e-255 xynT G MFS/sugar transport protein
HOCPNFDN_01448 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HOCPNFDN_01449 1e-215 xylR GK ROK family
HOCPNFDN_01450 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HOCPNFDN_01451 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HOCPNFDN_01452 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
HOCPNFDN_01453 3.5e-247 iolT EGP Major facilitator Superfamily
HOCPNFDN_01454 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOCPNFDN_01455 6.3e-84 yncE S Protein of unknown function (DUF2691)
HOCPNFDN_01456 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HOCPNFDN_01457 5.2e-15
HOCPNFDN_01460 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOCPNFDN_01462 1.3e-134 S Domain of unknown function, YrpD
HOCPNFDN_01465 7.9e-25 tatA U protein secretion
HOCPNFDN_01466 1.8e-71
HOCPNFDN_01467 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HOCPNFDN_01470 5.7e-286 gerAA EG Spore germination protein
HOCPNFDN_01471 4.5e-197 gerAB U Spore germination
HOCPNFDN_01472 4.2e-220 gerLC S Spore germination protein
HOCPNFDN_01473 7.7e-154 yndG S DoxX-like family
HOCPNFDN_01474 2.6e-117 yndH S Domain of unknown function (DUF4166)
HOCPNFDN_01475 0.0 yndJ S YndJ-like protein
HOCPNFDN_01477 8.6e-139 yndL S Replication protein
HOCPNFDN_01478 5.8e-74 yndM S Protein of unknown function (DUF2512)
HOCPNFDN_01479 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HOCPNFDN_01481 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HOCPNFDN_01482 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HOCPNFDN_01483 9.2e-113 yneB L resolvase
HOCPNFDN_01484 1.3e-32 ynzC S UPF0291 protein
HOCPNFDN_01485 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HOCPNFDN_01486 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HOCPNFDN_01487 1.8e-28 yneF S UPF0154 protein
HOCPNFDN_01488 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HOCPNFDN_01489 7.1e-127 ccdA O cytochrome c biogenesis protein
HOCPNFDN_01490 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HOCPNFDN_01491 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HOCPNFDN_01492 4.2e-74 yneK S Protein of unknown function (DUF2621)
HOCPNFDN_01493 4.1e-65 hspX O Spore coat protein
HOCPNFDN_01494 3.9e-19 sspP S Belongs to the SspP family
HOCPNFDN_01495 2.2e-14 sspO S Belongs to the SspO family
HOCPNFDN_01496 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HOCPNFDN_01497 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HOCPNFDN_01499 3.1e-08 sspN S Small acid-soluble spore protein N family
HOCPNFDN_01500 3.9e-35 tlp S Belongs to the Tlp family
HOCPNFDN_01501 1.2e-73 yneP S Thioesterase-like superfamily
HOCPNFDN_01502 1.3e-53 yneQ
HOCPNFDN_01503 4.1e-49 yneR S Belongs to the HesB IscA family
HOCPNFDN_01504 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HOCPNFDN_01505 6.6e-69 yccU S CoA-binding protein
HOCPNFDN_01506 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOCPNFDN_01507 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOCPNFDN_01508 2.3e-12
HOCPNFDN_01509 1.3e-57 ynfC
HOCPNFDN_01510 8.2e-252 agcS E Sodium alanine symporter
HOCPNFDN_01511 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HOCPNFDN_01513 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HOCPNFDN_01514 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HOCPNFDN_01515 2.4e-80 yngA S membrane
HOCPNFDN_01516 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HOCPNFDN_01517 5.5e-104 yngC S membrane-associated protein
HOCPNFDN_01518 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
HOCPNFDN_01519 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HOCPNFDN_01520 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HOCPNFDN_01521 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HOCPNFDN_01522 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HOCPNFDN_01523 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HOCPNFDN_01524 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HOCPNFDN_01525 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HOCPNFDN_01526 1.8e-31 S Family of unknown function (DUF5367)
HOCPNFDN_01527 1.3e-306 yngK T Glycosyl hydrolase-like 10
HOCPNFDN_01528 2.8e-64 yngL S Protein of unknown function (DUF1360)
HOCPNFDN_01529 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HOCPNFDN_01530 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCPNFDN_01531 1.4e-83 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HOCPNFDN_01532 2.1e-67 yqhY S protein conserved in bacteria
HOCPNFDN_01533 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOCPNFDN_01534 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HOCPNFDN_01535 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOCPNFDN_01536 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOCPNFDN_01537 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HOCPNFDN_01538 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOCPNFDN_01539 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HOCPNFDN_01540 1.7e-78 argR K Regulates arginine biosynthesis genes
HOCPNFDN_01541 0.0 recN L May be involved in recombinational repair of damaged DNA
HOCPNFDN_01542 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HOCPNFDN_01543 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HOCPNFDN_01545 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HOCPNFDN_01546 5.9e-27
HOCPNFDN_01547 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HOCPNFDN_01548 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HOCPNFDN_01549 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
HOCPNFDN_01550 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
HOCPNFDN_01551 1.8e-212 mmgC I acyl-CoA dehydrogenase
HOCPNFDN_01552 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HOCPNFDN_01553 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HOCPNFDN_01554 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HOCPNFDN_01555 4e-34 yqzF S Protein of unknown function (DUF2627)
HOCPNFDN_01556 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HOCPNFDN_01557 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HOCPNFDN_01558 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HOCPNFDN_01559 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HOCPNFDN_01560 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HOCPNFDN_01561 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HOCPNFDN_01562 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HOCPNFDN_01563 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HOCPNFDN_01564 2.6e-152 bmrR K helix_turn_helix, mercury resistance
HOCPNFDN_01565 7.9e-208 norA EGP Major facilitator Superfamily
HOCPNFDN_01566 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HOCPNFDN_01567 9.3e-77 yqiW S Belongs to the UPF0403 family
HOCPNFDN_01568 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HOCPNFDN_01569 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HOCPNFDN_01570 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HOCPNFDN_01571 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
HOCPNFDN_01572 1.4e-98 yqjB S protein conserved in bacteria
HOCPNFDN_01574 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HOCPNFDN_01575 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HOCPNFDN_01576 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HOCPNFDN_01577 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
HOCPNFDN_01578 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOCPNFDN_01579 4.5e-24 yqzJ
HOCPNFDN_01580 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOCPNFDN_01581 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOCPNFDN_01582 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HOCPNFDN_01583 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HOCPNFDN_01584 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HOCPNFDN_01585 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HOCPNFDN_01586 0.0 rocB E arginine degradation protein
HOCPNFDN_01587 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOCPNFDN_01588 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HOCPNFDN_01589 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_01590 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HOCPNFDN_01591 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HOCPNFDN_01592 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOCPNFDN_01594 5.2e-226 yqjV G Major Facilitator Superfamily
HOCPNFDN_01596 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOCPNFDN_01597 2.2e-49 S YolD-like protein
HOCPNFDN_01598 3.6e-87 yqjY K acetyltransferase
HOCPNFDN_01599 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HOCPNFDN_01600 4.7e-196 yqkA K GrpB protein
HOCPNFDN_01601 2.8e-54 yqkB S Belongs to the HesB IscA family
HOCPNFDN_01602 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HOCPNFDN_01603 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HOCPNFDN_01604 4e-14 yqkE S Protein of unknown function (DUF3886)
HOCPNFDN_01605 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HOCPNFDN_01607 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HOCPNFDN_01608 3e-223 yqxK 3.6.4.12 L DNA helicase
HOCPNFDN_01609 4.5e-58 ansR K Transcriptional regulator
HOCPNFDN_01610 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HOCPNFDN_01611 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HOCPNFDN_01612 3.1e-235 mleN C Na H antiporter
HOCPNFDN_01613 5.5e-242 mleA 1.1.1.38 C malic enzyme
HOCPNFDN_01614 2e-32 yqkK
HOCPNFDN_01615 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HOCPNFDN_01616 2.4e-80 fur P Belongs to the Fur family
HOCPNFDN_01617 3.7e-37 S Protein of unknown function (DUF4227)
HOCPNFDN_01618 2.6e-166 xerD L recombinase XerD
HOCPNFDN_01619 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HOCPNFDN_01620 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HOCPNFDN_01621 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HOCPNFDN_01622 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HOCPNFDN_01623 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HOCPNFDN_01624 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOCPNFDN_01625 7.4e-112 spoVAA S Stage V sporulation protein AA
HOCPNFDN_01626 1e-67 spoVAB S Stage V sporulation protein AB
HOCPNFDN_01627 2.3e-78 spoVAC S stage V sporulation protein AC
HOCPNFDN_01628 9e-192 spoVAD I Stage V sporulation protein AD
HOCPNFDN_01629 2.2e-57 spoVAEB S stage V sporulation protein
HOCPNFDN_01630 1.4e-110 spoVAEA S stage V sporulation protein
HOCPNFDN_01631 1.4e-273 spoVAF EG Stage V sporulation protein AF
HOCPNFDN_01632 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HOCPNFDN_01633 1.3e-149 ypuA S Secreted protein
HOCPNFDN_01634 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOCPNFDN_01637 1.5e-17 S SNARE associated Golgi protein
HOCPNFDN_01638 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HOCPNFDN_01639 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HOCPNFDN_01640 6e-55 ypuD
HOCPNFDN_01641 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOCPNFDN_01642 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
HOCPNFDN_01643 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HOCPNFDN_01644 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HOCPNFDN_01645 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOCPNFDN_01646 4.1e-70 ypuF S Domain of unknown function (DUF309)
HOCPNFDN_01647 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HOCPNFDN_01648 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HOCPNFDN_01649 4e-98 ypuI S Protein of unknown function (DUF3907)
HOCPNFDN_01650 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HOCPNFDN_01651 3.5e-103 spmA S Spore maturation protein
HOCPNFDN_01652 1.9e-87 spmB S Spore maturation protein
HOCPNFDN_01653 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HOCPNFDN_01654 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HOCPNFDN_01655 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HOCPNFDN_01656 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HOCPNFDN_01657 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_01658 0.0 resE 2.7.13.3 T Histidine kinase
HOCPNFDN_01659 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HOCPNFDN_01660 6.8e-201 rsiX
HOCPNFDN_01661 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HOCPNFDN_01662 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOCPNFDN_01663 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HOCPNFDN_01664 4.7e-41 fer C Ferredoxin
HOCPNFDN_01665 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
HOCPNFDN_01666 3.2e-286 recQ 3.6.4.12 L DNA helicase
HOCPNFDN_01667 2.2e-100 ypbD S metal-dependent membrane protease
HOCPNFDN_01668 4.6e-81 ypbE M Lysin motif
HOCPNFDN_01669 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HOCPNFDN_01670 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HOCPNFDN_01671 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HOCPNFDN_01672 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HOCPNFDN_01673 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HOCPNFDN_01674 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HOCPNFDN_01675 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HOCPNFDN_01676 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HOCPNFDN_01677 9.2e-113 ypfA M Flagellar protein YcgR
HOCPNFDN_01678 1.8e-23 S Family of unknown function (DUF5359)
HOCPNFDN_01679 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HOCPNFDN_01680 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HOCPNFDN_01681 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HOCPNFDN_01682 1e-07 S YpzI-like protein
HOCPNFDN_01683 1.3e-102 yphA
HOCPNFDN_01684 2.5e-161 seaA S YIEGIA protein
HOCPNFDN_01685 1.6e-28 ypzH
HOCPNFDN_01686 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HOCPNFDN_01687 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HOCPNFDN_01688 1.6e-18 yphE S Protein of unknown function (DUF2768)
HOCPNFDN_01689 5.4e-138 yphF
HOCPNFDN_01690 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HOCPNFDN_01691 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HOCPNFDN_01692 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HOCPNFDN_01693 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HOCPNFDN_01694 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HOCPNFDN_01695 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HOCPNFDN_01696 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HOCPNFDN_01697 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HOCPNFDN_01698 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HOCPNFDN_01699 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HOCPNFDN_01700 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HOCPNFDN_01701 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HOCPNFDN_01702 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOCPNFDN_01703 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOCPNFDN_01704 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HOCPNFDN_01705 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HOCPNFDN_01706 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HOCPNFDN_01707 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HOCPNFDN_01708 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOCPNFDN_01709 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HOCPNFDN_01710 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HOCPNFDN_01711 4.1e-234 S COG0457 FOG TPR repeat
HOCPNFDN_01712 2.8e-99 ypiB S Belongs to the UPF0302 family
HOCPNFDN_01713 8.5e-78 ypiF S Protein of unknown function (DUF2487)
HOCPNFDN_01714 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HOCPNFDN_01715 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HOCPNFDN_01716 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HOCPNFDN_01717 4.4e-98 ypjA S membrane
HOCPNFDN_01718 6.1e-143 ypjB S sporulation protein
HOCPNFDN_01719 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HOCPNFDN_01720 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HOCPNFDN_01721 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HOCPNFDN_01722 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HOCPNFDN_01723 6.9e-130 bshB1 S proteins, LmbE homologs
HOCPNFDN_01724 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HOCPNFDN_01725 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HOCPNFDN_01726 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HOCPNFDN_01727 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HOCPNFDN_01728 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HOCPNFDN_01729 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HOCPNFDN_01730 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HOCPNFDN_01731 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HOCPNFDN_01732 3.4e-80 ypmB S protein conserved in bacteria
HOCPNFDN_01733 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HOCPNFDN_01734 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HOCPNFDN_01735 5.7e-129 dnaD L DNA replication protein DnaD
HOCPNFDN_01736 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HOCPNFDN_01737 4.7e-93 ypoC
HOCPNFDN_01738 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HOCPNFDN_01739 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HOCPNFDN_01740 2.6e-188 yppC S Protein of unknown function (DUF2515)
HOCPNFDN_01743 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HOCPNFDN_01745 1.2e-48 yppG S YppG-like protein
HOCPNFDN_01746 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HOCPNFDN_01747 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HOCPNFDN_01748 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HOCPNFDN_01749 1.3e-237 yprB L RNase_H superfamily
HOCPNFDN_01750 3.3e-92 ypsA S Belongs to the UPF0398 family
HOCPNFDN_01751 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HOCPNFDN_01752 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HOCPNFDN_01754 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HOCPNFDN_01755 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOCPNFDN_01756 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HOCPNFDN_01757 3.9e-187 ptxS K transcriptional
HOCPNFDN_01758 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HOCPNFDN_01759 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HOCPNFDN_01760 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HOCPNFDN_01761 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HOCPNFDN_01762 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HOCPNFDN_01763 1.6e-228 pbuX F xanthine
HOCPNFDN_01764 4.4e-208 bcsA Q Naringenin-chalcone synthase
HOCPNFDN_01765 5.1e-87 ypbQ S protein conserved in bacteria
HOCPNFDN_01766 0.0 ypbR S Dynamin family
HOCPNFDN_01767 1e-38 ypbS S Protein of unknown function (DUF2533)
HOCPNFDN_01768 2e-07
HOCPNFDN_01769 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HOCPNFDN_01771 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
HOCPNFDN_01772 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HOCPNFDN_01773 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HOCPNFDN_01774 2.6e-27 ypeQ S Zinc-finger
HOCPNFDN_01775 8.1e-31 S Protein of unknown function (DUF2564)
HOCPNFDN_01776 3.8e-16 degR
HOCPNFDN_01777 7.9e-31 cspD K Cold-shock protein
HOCPNFDN_01778 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HOCPNFDN_01779 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HOCPNFDN_01780 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HOCPNFDN_01781 3.1e-110 ypgQ S phosphohydrolase
HOCPNFDN_01782 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
HOCPNFDN_01783 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HOCPNFDN_01784 1.7e-75 yphP S Belongs to the UPF0403 family
HOCPNFDN_01785 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HOCPNFDN_01786 7.8e-114 ypjP S YpjP-like protein
HOCPNFDN_01787 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HOCPNFDN_01788 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOCPNFDN_01789 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HOCPNFDN_01790 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HOCPNFDN_01791 4.2e-110 hlyIII S protein, Hemolysin III
HOCPNFDN_01792 1.6e-185 pspF K Transcriptional regulator
HOCPNFDN_01793 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HOCPNFDN_01794 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HOCPNFDN_01795 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HOCPNFDN_01796 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HOCPNFDN_01797 5e-99 ypmS S protein conserved in bacteria
HOCPNFDN_01798 5.5e-29 ypmT S Uncharacterized ympT
HOCPNFDN_01799 2.6e-223 mepA V MATE efflux family protein
HOCPNFDN_01800 1.6e-70 ypoP K transcriptional
HOCPNFDN_01801 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOCPNFDN_01802 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HOCPNFDN_01803 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
HOCPNFDN_01804 2.7e-307 yokA L Recombinase
HOCPNFDN_01805 1.6e-107
HOCPNFDN_01806 8.9e-95
HOCPNFDN_01809 8.4e-156 aacC 2.3.1.81 V aminoglycoside
HOCPNFDN_01810 1.1e-83 S Bacterial PH domain
HOCPNFDN_01811 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
HOCPNFDN_01812 4.1e-203
HOCPNFDN_01813 6.7e-92 yokH G SMI1 / KNR4 family
HOCPNFDN_01814 1.2e-302 UW nuclease activity
HOCPNFDN_01815 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
HOCPNFDN_01816 3.2e-109 yokK S SMI1 / KNR4 family
HOCPNFDN_01817 2.8e-99 J Acetyltransferase (GNAT) domain
HOCPNFDN_01819 6.8e-09 S Domain of unknown function (DUF4879)
HOCPNFDN_01821 1.3e-37
HOCPNFDN_01822 5.8e-55 S YolD-like protein
HOCPNFDN_01823 1.9e-239 S impB/mucB/samB family C-terminal domain
HOCPNFDN_01826 0.0 V Peptidase C39 family
HOCPNFDN_01827 1.2e-70 CO cell redox homeostasis
HOCPNFDN_01828 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HOCPNFDN_01829 3.4e-74 O protein disulfide oxidoreductase activity
HOCPNFDN_01830 5.5e-40 S SPP1 phage holin
HOCPNFDN_01831 4.4e-32 bhlA S BhlA holin family
HOCPNFDN_01832 1.6e-186 3.5.1.28 M Ami_2
HOCPNFDN_01834 6.5e-164
HOCPNFDN_01835 0.0 G Exopolysaccharide biosynthesis protein
HOCPNFDN_01836 6.4e-115
HOCPNFDN_01837 0.0 S Pfam Transposase IS66
HOCPNFDN_01838 6.2e-145 S Phage tail protein
HOCPNFDN_01839 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HOCPNFDN_01840 9.3e-116
HOCPNFDN_01845 2.1e-193 xerH A Belongs to the 'phage' integrase family
HOCPNFDN_01846 6.3e-70
HOCPNFDN_01847 2.5e-86
HOCPNFDN_01848 2.5e-10 xkdX
HOCPNFDN_01849 8.1e-07
HOCPNFDN_01850 1.1e-172
HOCPNFDN_01851 1e-57
HOCPNFDN_01854 1.6e-90
HOCPNFDN_01855 8.1e-131
HOCPNFDN_01856 2.6e-91
HOCPNFDN_01857 1.4e-121
HOCPNFDN_01859 1.1e-68
HOCPNFDN_01860 5.1e-81
HOCPNFDN_01861 5.7e-186
HOCPNFDN_01862 1.6e-94
HOCPNFDN_01863 2.1e-266
HOCPNFDN_01864 6.3e-282
HOCPNFDN_01865 0.0 gp17a S Terminase-like family
HOCPNFDN_01866 1.8e-175
HOCPNFDN_01869 2.6e-230
HOCPNFDN_01871 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HOCPNFDN_01872 0.0
HOCPNFDN_01875 5.7e-55 bldD K domain, Protein
HOCPNFDN_01876 4e-17
HOCPNFDN_01878 5.9e-238
HOCPNFDN_01880 1.4e-256
HOCPNFDN_01881 4.6e-35 K Cro/C1-type HTH DNA-binding domain
HOCPNFDN_01882 3.8e-259
HOCPNFDN_01883 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
HOCPNFDN_01888 1.1e-96 S Super-infection exclusion protein B
HOCPNFDN_01889 1.2e-86
HOCPNFDN_01891 6.6e-106
HOCPNFDN_01896 6.8e-198 L Belongs to the 'phage' integrase family
HOCPNFDN_01897 6e-263 S DNA-sulfur modification-associated
HOCPNFDN_01898 2.1e-177
HOCPNFDN_01899 1.1e-33 K Transcriptional regulator
HOCPNFDN_01910 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
HOCPNFDN_01911 8.8e-12 S Protein of unknown function (DUF2815)
HOCPNFDN_01914 3e-78 yoqH M LysM domain
HOCPNFDN_01916 1.5e-97 S Protein of unknown function (DUF1273)
HOCPNFDN_01918 1e-44
HOCPNFDN_01925 2.3e-77
HOCPNFDN_01926 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HOCPNFDN_01927 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
HOCPNFDN_01930 7.7e-149 S Pfam:DUF867
HOCPNFDN_01931 0.0 M Parallel beta-helix repeats
HOCPNFDN_01936 1.3e-170
HOCPNFDN_01937 7.6e-180 L AAA domain
HOCPNFDN_01938 1.4e-86
HOCPNFDN_01939 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
HOCPNFDN_01940 1.2e-224 L DNA primase activity
HOCPNFDN_01941 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HOCPNFDN_01942 0.0 2.7.7.7 L DNA polymerase
HOCPNFDN_01943 9.9e-115 DR0488 S protein conserved in bacteria
HOCPNFDN_01948 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
HOCPNFDN_01949 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HOCPNFDN_01951 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HOCPNFDN_01968 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HOCPNFDN_01969 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOCPNFDN_01970 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOCPNFDN_01971 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOCPNFDN_01972 3.3e-97 L HNH endonuclease
HOCPNFDN_01973 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOCPNFDN_01974 6.1e-38 O Glutaredoxin
HOCPNFDN_01975 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HOCPNFDN_01976 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
HOCPNFDN_01981 2.5e-30 sspB S spore protein
HOCPNFDN_01982 1.9e-168 S Calcineurin-like phosphoesterase
HOCPNFDN_01990 1.4e-10 K Cro/C1-type HTH DNA-binding domain
HOCPNFDN_01991 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HOCPNFDN_01993 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
HOCPNFDN_01994 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HOCPNFDN_01995 3.3e-188 cgeB S Spore maturation protein
HOCPNFDN_01996 1.2e-65 cgeA
HOCPNFDN_01997 3.5e-38 cgeC
HOCPNFDN_01998 1e-256 cgeD M maturation of the outermost layer of the spore
HOCPNFDN_01999 2.9e-145 yiiD K acetyltransferase
HOCPNFDN_02002 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOCPNFDN_02003 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HOCPNFDN_02004 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HOCPNFDN_02005 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
HOCPNFDN_02006 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HOCPNFDN_02007 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HOCPNFDN_02008 2.9e-47 yokU S YokU-like protein, putative antitoxin
HOCPNFDN_02009 1.4e-36 yozE S Belongs to the UPF0346 family
HOCPNFDN_02010 1.4e-124 yodN
HOCPNFDN_02012 2.8e-24 yozD S YozD-like protein
HOCPNFDN_02013 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
HOCPNFDN_02014 3.6e-54 yodL S YodL-like
HOCPNFDN_02015 5.3e-09
HOCPNFDN_02016 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HOCPNFDN_02017 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HOCPNFDN_02018 5.2e-24 yodI
HOCPNFDN_02019 1.7e-128 yodH Q Methyltransferase
HOCPNFDN_02020 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HOCPNFDN_02021 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOCPNFDN_02022 6.2e-28 S Protein of unknown function (DUF3311)
HOCPNFDN_02023 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
HOCPNFDN_02024 3.8e-113 mhqD S Carboxylesterase
HOCPNFDN_02025 4.8e-108 yodC C nitroreductase
HOCPNFDN_02026 1.7e-57 yodB K transcriptional
HOCPNFDN_02027 3.8e-66 yodA S tautomerase
HOCPNFDN_02028 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
HOCPNFDN_02029 3.4e-09
HOCPNFDN_02030 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
HOCPNFDN_02031 3.5e-163 rarD S -transporter
HOCPNFDN_02032 1.5e-43
HOCPNFDN_02033 2.2e-60 yojF S Protein of unknown function (DUF1806)
HOCPNFDN_02034 2.1e-125 yojG S deacetylase
HOCPNFDN_02035 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HOCPNFDN_02036 4.2e-245 norM V Multidrug efflux pump
HOCPNFDN_02038 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HOCPNFDN_02039 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HOCPNFDN_02040 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HOCPNFDN_02041 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HOCPNFDN_02042 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
HOCPNFDN_02043 0.0 yojO P Von Willebrand factor
HOCPNFDN_02044 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HOCPNFDN_02045 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HOCPNFDN_02046 1.1e-167 yocS S -transporter
HOCPNFDN_02047 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HOCPNFDN_02048 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
HOCPNFDN_02049 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HOCPNFDN_02050 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HOCPNFDN_02051 2.7e-31 yozC
HOCPNFDN_02052 4.2e-56 yozO S Bacterial PH domain
HOCPNFDN_02053 1.9e-36 yocN
HOCPNFDN_02054 1.1e-40 yozN
HOCPNFDN_02055 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HOCPNFDN_02056 6.6e-34
HOCPNFDN_02057 6.4e-54 yocL
HOCPNFDN_02058 3.3e-83 dksA T general stress protein
HOCPNFDN_02059 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HOCPNFDN_02060 0.0 recQ 3.6.4.12 L DNA helicase
HOCPNFDN_02061 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HOCPNFDN_02062 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOCPNFDN_02063 3.2e-198 desK 2.7.13.3 T Histidine kinase
HOCPNFDN_02064 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HOCPNFDN_02065 6.9e-189 yocD 3.4.17.13 V peptidase S66
HOCPNFDN_02066 1.9e-94 yocC
HOCPNFDN_02067 2.2e-145
HOCPNFDN_02068 1.5e-92 yozB S membrane
HOCPNFDN_02069 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HOCPNFDN_02070 1e-51 czrA K transcriptional
HOCPNFDN_02071 2.5e-95 yobW
HOCPNFDN_02072 9e-178 yobV K WYL domain
HOCPNFDN_02073 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
HOCPNFDN_02074 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HOCPNFDN_02075 3e-99 yobS K Transcriptional regulator
HOCPNFDN_02076 2.5e-143 yobR 2.3.1.1 J FR47-like protein
HOCPNFDN_02077 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
HOCPNFDN_02078 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HOCPNFDN_02079 0.0 yobO M Pectate lyase superfamily protein
HOCPNFDN_02080 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HOCPNFDN_02081 7.9e-105 yokH G SMI1 / KNR4 family
HOCPNFDN_02082 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HOCPNFDN_02083 3e-86 S SMI1-KNR4 cell-wall
HOCPNFDN_02084 2.7e-157 yobJ
HOCPNFDN_02085 0.0 K Psort location Cytoplasmic, score
HOCPNFDN_02086 1.2e-49
HOCPNFDN_02087 2.6e-38 S YolD-like protein
HOCPNFDN_02088 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOCPNFDN_02089 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOCPNFDN_02091 1.7e-207 S aspartate phosphatase
HOCPNFDN_02096 1.8e-178 yobF
HOCPNFDN_02097 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
HOCPNFDN_02098 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
HOCPNFDN_02100 5.7e-58 K Helix-turn-helix
HOCPNFDN_02101 1.4e-37 S TM2 domain
HOCPNFDN_02102 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HOCPNFDN_02103 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HOCPNFDN_02107 2.3e-170 bla 3.5.2.6 V beta-lactamase
HOCPNFDN_02108 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HOCPNFDN_02109 3.7e-78 yoaW
HOCPNFDN_02110 6e-160 yijE EG EamA-like transporter family
HOCPNFDN_02111 8.6e-159 yoaU K LysR substrate binding domain
HOCPNFDN_02112 1.1e-149 yoaT S Protein of unknown function (DUF817)
HOCPNFDN_02113 4.2e-37 yozG K Transcriptional regulator
HOCPNFDN_02114 4.3e-75 yoaS S Protein of unknown function (DUF2975)
HOCPNFDN_02115 2.4e-172 yoaR V vancomycin resistance protein
HOCPNFDN_02116 4.1e-89
HOCPNFDN_02117 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
HOCPNFDN_02118 1.5e-146 yoaP 3.1.3.18 K YoaP-like
HOCPNFDN_02120 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
HOCPNFDN_02122 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
HOCPNFDN_02123 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HOCPNFDN_02124 2.3e-111 yoaK S Membrane
HOCPNFDN_02125 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HOCPNFDN_02126 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HOCPNFDN_02127 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
HOCPNFDN_02128 1.5e-38 S Protein of unknown function (DUF4025)
HOCPNFDN_02129 7e-14
HOCPNFDN_02130 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
HOCPNFDN_02131 1.9e-33 yoaF
HOCPNFDN_02132 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HOCPNFDN_02133 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOCPNFDN_02134 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HOCPNFDN_02135 6.2e-235 yoaB EGP Major facilitator Superfamily
HOCPNFDN_02136 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HOCPNFDN_02137 3.1e-144 yoxB
HOCPNFDN_02138 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
HOCPNFDN_02139 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_02140 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HOCPNFDN_02141 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOCPNFDN_02142 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOCPNFDN_02143 7.8e-155 gltC K Transcriptional regulator
HOCPNFDN_02144 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HOCPNFDN_02145 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HOCPNFDN_02146 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HOCPNFDN_02147 2.5e-158 gltR1 K Transcriptional regulator
HOCPNFDN_02148 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HOCPNFDN_02149 3e-34 yoeD G Helix-turn-helix domain
HOCPNFDN_02150 2.2e-96 L Integrase
HOCPNFDN_02152 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HOCPNFDN_02153 2.3e-246 yoeA V MATE efflux family protein
HOCPNFDN_02154 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
HOCPNFDN_02155 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HOCPNFDN_02156 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCPNFDN_02157 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCPNFDN_02158 8.3e-96 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCPNFDN_02159 7.8e-08
HOCPNFDN_02168 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HOCPNFDN_02169 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HOCPNFDN_02170 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HOCPNFDN_02171 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HOCPNFDN_02172 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HOCPNFDN_02173 9.9e-77 tspO T membrane
HOCPNFDN_02174 1.8e-206 cotI S Spore coat protein
HOCPNFDN_02175 1.8e-217 cotSA M Glycosyl transferases group 1
HOCPNFDN_02176 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
HOCPNFDN_02178 3.6e-235 ytcC M Glycosyltransferase Family 4
HOCPNFDN_02179 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HOCPNFDN_02180 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HOCPNFDN_02181 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
HOCPNFDN_02182 2.6e-132 dksA T COG1734 DnaK suppressor protein
HOCPNFDN_02183 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
HOCPNFDN_02184 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HOCPNFDN_02185 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HOCPNFDN_02186 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HOCPNFDN_02187 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HOCPNFDN_02188 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HOCPNFDN_02189 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
HOCPNFDN_02190 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HOCPNFDN_02191 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HOCPNFDN_02192 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HOCPNFDN_02193 1.1e-24 S Domain of Unknown Function (DUF1540)
HOCPNFDN_02194 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HOCPNFDN_02195 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
HOCPNFDN_02196 3.6e-41 rpmE2 J Ribosomal protein L31
HOCPNFDN_02197 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HOCPNFDN_02198 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HOCPNFDN_02199 3.6e-73 ytkA S YtkA-like
HOCPNFDN_02201 2.1e-76 dps P Belongs to the Dps family
HOCPNFDN_02202 5.4e-63 ytkC S Bacteriophage holin family
HOCPNFDN_02203 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HOCPNFDN_02204 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HOCPNFDN_02205 1.4e-144 ytlC P ABC transporter
HOCPNFDN_02206 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HOCPNFDN_02207 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HOCPNFDN_02208 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HOCPNFDN_02209 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HOCPNFDN_02210 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOCPNFDN_02211 0.0 asnB 6.3.5.4 E Asparagine synthase
HOCPNFDN_02212 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HOCPNFDN_02213 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HOCPNFDN_02214 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HOCPNFDN_02215 5.7e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HOCPNFDN_02216 3.3e-106 ytqB J Putative rRNA methylase
HOCPNFDN_02217 2.1e-190 yhcC S Fe-S oxidoreductase
HOCPNFDN_02218 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HOCPNFDN_02220 5.1e-66 ytrA K GntR family transcriptional regulator
HOCPNFDN_02221 1.1e-161 ytrB P abc transporter atp-binding protein
HOCPNFDN_02222 6.1e-169 P ABC-2 family transporter protein
HOCPNFDN_02223 5.9e-148
HOCPNFDN_02224 3.1e-127 ytrE V ABC transporter, ATP-binding protein
HOCPNFDN_02225 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HOCPNFDN_02226 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_02227 5.6e-186 T PhoQ Sensor
HOCPNFDN_02228 1.1e-138 bceA V ABC transporter, ATP-binding protein
HOCPNFDN_02229 0.0 bceB V ABC transporter (permease)
HOCPNFDN_02230 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HOCPNFDN_02231 2.1e-211 yttB EGP Major facilitator Superfamily
HOCPNFDN_02232 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HOCPNFDN_02233 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HOCPNFDN_02234 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOCPNFDN_02235 2.1e-51 ytwF P Sulfurtransferase
HOCPNFDN_02236 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HOCPNFDN_02237 1.5e-144 amyC P ABC transporter (permease)
HOCPNFDN_02238 3.7e-168 amyD P ABC transporter
HOCPNFDN_02239 2.3e-248 msmE G Bacterial extracellular solute-binding protein
HOCPNFDN_02240 2.3e-190 msmR K Transcriptional regulator
HOCPNFDN_02241 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
HOCPNFDN_02242 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HOCPNFDN_02243 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HOCPNFDN_02244 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HOCPNFDN_02245 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HOCPNFDN_02246 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HOCPNFDN_02247 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
HOCPNFDN_02248 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HOCPNFDN_02249 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HOCPNFDN_02250 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HOCPNFDN_02251 0.0 ytdP K Transcriptional regulator
HOCPNFDN_02252 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HOCPNFDN_02253 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HOCPNFDN_02254 4.6e-73 yteS G transport
HOCPNFDN_02255 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HOCPNFDN_02256 4.8e-117 yteU S Integral membrane protein
HOCPNFDN_02257 3.1e-26 yteV S Sporulation protein Cse60
HOCPNFDN_02258 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HOCPNFDN_02259 8.2e-232 ytfP S HI0933-like protein
HOCPNFDN_02260 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOCPNFDN_02261 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HOCPNFDN_02262 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HOCPNFDN_02263 4.3e-132 ythP V ABC transporter
HOCPNFDN_02264 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
HOCPNFDN_02265 7.2e-226 pbuO S permease
HOCPNFDN_02266 7.1e-272 pepV 3.5.1.18 E Dipeptidase
HOCPNFDN_02267 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HOCPNFDN_02268 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HOCPNFDN_02269 1.3e-165 ytlQ
HOCPNFDN_02270 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HOCPNFDN_02271 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HOCPNFDN_02272 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HOCPNFDN_02273 2e-45 ytzH S YtzH-like protein
HOCPNFDN_02274 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HOCPNFDN_02275 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HOCPNFDN_02276 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HOCPNFDN_02277 9.8e-52 ytzB S small secreted protein
HOCPNFDN_02278 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HOCPNFDN_02279 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HOCPNFDN_02280 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HOCPNFDN_02281 9.8e-149 ytpQ S Belongs to the UPF0354 family
HOCPNFDN_02282 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOCPNFDN_02283 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HOCPNFDN_02284 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HOCPNFDN_02285 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HOCPNFDN_02286 6.6e-17 ytxH S COG4980 Gas vesicle protein
HOCPNFDN_02287 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
HOCPNFDN_02288 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HOCPNFDN_02289 1.7e-182 ccpA K catabolite control protein A
HOCPNFDN_02290 7.1e-147 motA N flagellar motor
HOCPNFDN_02291 1.4e-125 motS N Flagellar motor protein
HOCPNFDN_02292 1.9e-225 acuC BQ histone deacetylase
HOCPNFDN_02293 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HOCPNFDN_02294 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HOCPNFDN_02295 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HOCPNFDN_02296 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOCPNFDN_02298 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HOCPNFDN_02299 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HOCPNFDN_02300 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HOCPNFDN_02301 3.4e-109 yttP K Transcriptional regulator
HOCPNFDN_02302 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HOCPNFDN_02303 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HOCPNFDN_02304 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HOCPNFDN_02305 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
HOCPNFDN_02306 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOCPNFDN_02307 2e-29 sspB S spore protein
HOCPNFDN_02308 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HOCPNFDN_02309 0.0 ytcJ S amidohydrolase
HOCPNFDN_02310 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOCPNFDN_02311 2.4e-181 sppA OU signal peptide peptidase SppA
HOCPNFDN_02312 1.3e-87 yteJ S RDD family
HOCPNFDN_02313 5.6e-116 ytfI S Protein of unknown function (DUF2953)
HOCPNFDN_02314 8.7e-70 ytfJ S Sporulation protein YtfJ
HOCPNFDN_02315 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HOCPNFDN_02316 7e-165 ytxK 2.1.1.72 L DNA methylase
HOCPNFDN_02317 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOCPNFDN_02318 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HOCPNFDN_02319 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HOCPNFDN_02320 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
HOCPNFDN_02322 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOCPNFDN_02323 1.7e-130 ytkL S Belongs to the UPF0173 family
HOCPNFDN_02324 2.9e-173 ytlI K LysR substrate binding domain
HOCPNFDN_02325 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
HOCPNFDN_02326 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
HOCPNFDN_02327 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
HOCPNFDN_02328 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
HOCPNFDN_02329 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
HOCPNFDN_02330 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HOCPNFDN_02331 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOCPNFDN_02332 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
HOCPNFDN_02333 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOCPNFDN_02334 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HOCPNFDN_02335 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
HOCPNFDN_02336 1.2e-158 ytnM S membrane transporter protein
HOCPNFDN_02337 8e-241 ytoI K transcriptional regulator containing CBS domains
HOCPNFDN_02338 2.4e-47 ytpI S YtpI-like protein
HOCPNFDN_02339 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HOCPNFDN_02340 9.2e-29
HOCPNFDN_02341 8.2e-69 ytrI
HOCPNFDN_02342 3.2e-56 ytrH S Sporulation protein YtrH
HOCPNFDN_02343 0.0 dnaE 2.7.7.7 L DNA polymerase
HOCPNFDN_02344 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HOCPNFDN_02345 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HOCPNFDN_02346 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HOCPNFDN_02347 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HOCPNFDN_02348 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HOCPNFDN_02349 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HOCPNFDN_02350 2.6e-192 ytvI S sporulation integral membrane protein YtvI
HOCPNFDN_02351 4.7e-71 yeaL S membrane
HOCPNFDN_02352 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HOCPNFDN_02353 1.8e-242 icd 1.1.1.42 C isocitrate
HOCPNFDN_02354 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HOCPNFDN_02355 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_02356 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HOCPNFDN_02357 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOCPNFDN_02358 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HOCPNFDN_02359 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HOCPNFDN_02360 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HOCPNFDN_02361 8.9e-161 ytbE S reductase
HOCPNFDN_02362 4.9e-205 ytbD EGP Major facilitator Superfamily
HOCPNFDN_02363 9.9e-67 ytcD K Transcriptional regulator
HOCPNFDN_02364 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOCPNFDN_02365 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HOCPNFDN_02366 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOCPNFDN_02367 3.5e-266 dnaB L Membrane attachment protein
HOCPNFDN_02368 3e-173 dnaI L Primosomal protein DnaI
HOCPNFDN_02369 4.9e-111 ytxB S SNARE associated Golgi protein
HOCPNFDN_02370 3.8e-159 ytxC S YtxC-like family
HOCPNFDN_02371 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOCPNFDN_02372 1.5e-149 ysaA S HAD-hyrolase-like
HOCPNFDN_02373 0.0 lytS 2.7.13.3 T Histidine kinase
HOCPNFDN_02374 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
HOCPNFDN_02375 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HOCPNFDN_02376 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HOCPNFDN_02378 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HOCPNFDN_02379 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HOCPNFDN_02380 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HOCPNFDN_02381 7.5e-45 ysdA S Membrane
HOCPNFDN_02382 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HOCPNFDN_02383 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HOCPNFDN_02384 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HOCPNFDN_02385 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HOCPNFDN_02386 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HOCPNFDN_02387 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HOCPNFDN_02388 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HOCPNFDN_02389 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HOCPNFDN_02390 2.8e-254 araN G carbohydrate transport
HOCPNFDN_02391 1.4e-167 araP G carbohydrate transport
HOCPNFDN_02392 3.4e-144 araQ G transport system permease
HOCPNFDN_02393 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HOCPNFDN_02394 0.0 cstA T Carbon starvation protein
HOCPNFDN_02396 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
HOCPNFDN_02397 5.6e-258 glcF C Glycolate oxidase
HOCPNFDN_02398 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
HOCPNFDN_02399 4.4e-208 ysfB KT regulator
HOCPNFDN_02400 2.6e-32 sspI S Belongs to the SspI family
HOCPNFDN_02401 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOCPNFDN_02402 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HOCPNFDN_02403 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOCPNFDN_02404 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOCPNFDN_02405 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HOCPNFDN_02406 1.3e-85 cvpA S membrane protein, required for colicin V production
HOCPNFDN_02407 0.0 polX L COG1796 DNA polymerase IV (family X)
HOCPNFDN_02408 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HOCPNFDN_02409 7.3e-68 yshE S membrane
HOCPNFDN_02410 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HOCPNFDN_02411 2.7e-100 fadR K Transcriptional regulator
HOCPNFDN_02412 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HOCPNFDN_02413 1.2e-135 etfB C Electron transfer flavoprotein
HOCPNFDN_02414 4.2e-178 etfA C Electron transfer flavoprotein
HOCPNFDN_02416 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HOCPNFDN_02417 2e-52 trxA O Belongs to the thioredoxin family
HOCPNFDN_02418 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HOCPNFDN_02419 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HOCPNFDN_02420 1.2e-79 yslB S Protein of unknown function (DUF2507)
HOCPNFDN_02421 2.4e-107 sdhC C succinate dehydrogenase
HOCPNFDN_02422 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HOCPNFDN_02423 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HOCPNFDN_02424 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HOCPNFDN_02425 3.3e-30 gerE K Transcriptional regulator
HOCPNFDN_02426 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HOCPNFDN_02427 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HOCPNFDN_02428 2.9e-196 gerM S COG5401 Spore germination protein
HOCPNFDN_02429 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HOCPNFDN_02430 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOCPNFDN_02431 1.4e-92 ysnB S Phosphoesterase
HOCPNFDN_02433 9.1e-134 ysnF S protein conserved in bacteria
HOCPNFDN_02434 7.6e-82 ysnE K acetyltransferase
HOCPNFDN_02436 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HOCPNFDN_02437 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HOCPNFDN_02438 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOCPNFDN_02439 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOCPNFDN_02440 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HOCPNFDN_02441 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOCPNFDN_02442 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOCPNFDN_02443 2.3e-187 ysoA H Tetratricopeptide repeat
HOCPNFDN_02444 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HOCPNFDN_02445 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HOCPNFDN_02446 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HOCPNFDN_02447 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HOCPNFDN_02448 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HOCPNFDN_02449 1.4e-89 ysxD
HOCPNFDN_02450 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HOCPNFDN_02451 3.6e-146 hemX O cytochrome C
HOCPNFDN_02452 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HOCPNFDN_02453 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HOCPNFDN_02454 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
HOCPNFDN_02455 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HOCPNFDN_02456 1.9e-226 spoVID M stage VI sporulation protein D
HOCPNFDN_02457 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HOCPNFDN_02458 1.6e-25
HOCPNFDN_02459 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HOCPNFDN_02460 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HOCPNFDN_02461 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HOCPNFDN_02462 1.1e-168 spoIIB S Sporulation related domain
HOCPNFDN_02463 2.8e-102 maf D septum formation protein Maf
HOCPNFDN_02464 5.9e-126 radC E Belongs to the UPF0758 family
HOCPNFDN_02465 1.8e-184 mreB D Rod shape-determining protein MreB
HOCPNFDN_02466 2.8e-157 mreC M Involved in formation and maintenance of cell shape
HOCPNFDN_02467 1.4e-84 mreD M shape-determining protein
HOCPNFDN_02468 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HOCPNFDN_02469 2.5e-144 minD D Belongs to the ParA family
HOCPNFDN_02470 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HOCPNFDN_02471 9.2e-161 spoIVFB S Stage IV sporulation protein
HOCPNFDN_02472 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HOCPNFDN_02473 4.1e-56 ysxB J ribosomal protein
HOCPNFDN_02474 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HOCPNFDN_02475 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HOCPNFDN_02476 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOCPNFDN_02477 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HOCPNFDN_02478 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
HOCPNFDN_02479 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HOCPNFDN_02480 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
HOCPNFDN_02481 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HOCPNFDN_02482 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HOCPNFDN_02483 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HOCPNFDN_02484 9.8e-158 safA M spore coat assembly protein SafA
HOCPNFDN_02485 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HOCPNFDN_02486 1.9e-127 yebC K transcriptional regulatory protein
HOCPNFDN_02487 1.8e-262 alsT E Sodium alanine symporter
HOCPNFDN_02488 2.6e-35 S Family of unknown function (DUF5412)
HOCPNFDN_02490 6.5e-119 yrzF T serine threonine protein kinase
HOCPNFDN_02491 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HOCPNFDN_02492 5.3e-253 csbX EGP Major facilitator Superfamily
HOCPNFDN_02493 4.8e-93 bofC S BofC C-terminal domain
HOCPNFDN_02494 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HOCPNFDN_02495 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HOCPNFDN_02496 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HOCPNFDN_02497 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HOCPNFDN_02498 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HOCPNFDN_02499 1.1e-38 yajC U Preprotein translocase subunit YajC
HOCPNFDN_02500 1.2e-74 yrzE S Protein of unknown function (DUF3792)
HOCPNFDN_02501 2.2e-114 yrbG S membrane
HOCPNFDN_02502 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOCPNFDN_02503 9.4e-49 yrzD S Post-transcriptional regulator
HOCPNFDN_02504 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HOCPNFDN_02505 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HOCPNFDN_02506 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HOCPNFDN_02507 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HOCPNFDN_02508 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOCPNFDN_02509 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOCPNFDN_02510 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HOCPNFDN_02511 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
HOCPNFDN_02513 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HOCPNFDN_02514 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HOCPNFDN_02515 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HOCPNFDN_02516 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HOCPNFDN_02517 1.2e-70 cymR K Transcriptional regulator
HOCPNFDN_02518 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
HOCPNFDN_02519 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HOCPNFDN_02520 1.4e-15 S COG0457 FOG TPR repeat
HOCPNFDN_02521 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HOCPNFDN_02522 1.8e-83 yrrD S protein conserved in bacteria
HOCPNFDN_02523 9.8e-31 yrzR
HOCPNFDN_02524 8e-08 S Protein of unknown function (DUF3918)
HOCPNFDN_02525 7.6e-107 glnP P ABC transporter
HOCPNFDN_02526 3.6e-109 gluC P ABC transporter
HOCPNFDN_02527 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
HOCPNFDN_02528 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HOCPNFDN_02529 2.7e-170 yrrI S AI-2E family transporter
HOCPNFDN_02530 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOCPNFDN_02531 1.7e-41 yrzL S Belongs to the UPF0297 family
HOCPNFDN_02532 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOCPNFDN_02533 1.2e-45 yrzB S Belongs to the UPF0473 family
HOCPNFDN_02534 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HOCPNFDN_02535 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
HOCPNFDN_02536 7.8e-174 yegQ O Peptidase U32
HOCPNFDN_02537 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HOCPNFDN_02538 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HOCPNFDN_02539 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOCPNFDN_02540 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HOCPNFDN_02541 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HOCPNFDN_02542 7e-27 yrzA S Protein of unknown function (DUF2536)
HOCPNFDN_02543 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HOCPNFDN_02544 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOCPNFDN_02545 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HOCPNFDN_02546 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HOCPNFDN_02547 4.6e-35 yrhC S YrhC-like protein
HOCPNFDN_02548 1.4e-78 yrhD S Protein of unknown function (DUF1641)
HOCPNFDN_02549 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HOCPNFDN_02550 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HOCPNFDN_02551 1.8e-142 focA P Formate nitrite
HOCPNFDN_02554 4.5e-97 yrhH Q methyltransferase
HOCPNFDN_02555 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HOCPNFDN_02556 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HOCPNFDN_02557 1.5e-46 yrhK S YrhK-like protein
HOCPNFDN_02558 0.0 yrhL I Acyltransferase family
HOCPNFDN_02559 1.7e-151 rsiV S Protein of unknown function (DUF3298)
HOCPNFDN_02560 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HOCPNFDN_02561 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
HOCPNFDN_02562 3.6e-106 yrhP E LysE type translocator
HOCPNFDN_02563 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HOCPNFDN_02564 0.0 levR K PTS system fructose IIA component
HOCPNFDN_02565 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
HOCPNFDN_02566 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HOCPNFDN_02567 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HOCPNFDN_02568 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HOCPNFDN_02569 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HOCPNFDN_02570 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HOCPNFDN_02571 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
HOCPNFDN_02572 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
HOCPNFDN_02573 4.3e-47 yraB K helix_turn_helix, mercury resistance
HOCPNFDN_02574 1.1e-49 yraD M Spore coat protein
HOCPNFDN_02575 2.6e-26 yraE
HOCPNFDN_02576 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HOCPNFDN_02577 6.4e-63 yraF M Spore coat protein
HOCPNFDN_02578 5.3e-37 yraG
HOCPNFDN_02579 1.3e-66 E Glyoxalase-like domain
HOCPNFDN_02580 2.4e-61 T sh3 domain protein
HOCPNFDN_02581 1.7e-60 T sh3 domain protein
HOCPNFDN_02582 3.2e-155 S Alpha beta hydrolase
HOCPNFDN_02583 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOCPNFDN_02584 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HOCPNFDN_02586 2.4e-206 yraM S PrpF protein
HOCPNFDN_02587 1.2e-163 yraN K Transcriptional regulator
HOCPNFDN_02588 9.5e-226 yraO C Citrate transporter
HOCPNFDN_02589 4.5e-188 yrpG C Aldo/keto reductase family
HOCPNFDN_02590 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HOCPNFDN_02591 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HOCPNFDN_02593 3e-125 yrpD S Domain of unknown function, YrpD
HOCPNFDN_02594 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HOCPNFDN_02595 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HOCPNFDN_02596 7.6e-168 aadK G Streptomycin adenylyltransferase
HOCPNFDN_02597 1.2e-91 yrdA S DinB family
HOCPNFDN_02598 1.9e-57 S Protein of unknown function (DUF2568)
HOCPNFDN_02599 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
HOCPNFDN_02600 4.1e-231 cypA C Cytochrome P450
HOCPNFDN_02601 4.1e-46 yrdF K ribonuclease inhibitor
HOCPNFDN_02602 2.2e-79 bkdR K helix_turn_helix ASNC type
HOCPNFDN_02603 3.3e-138 azlC E AzlC protein
HOCPNFDN_02604 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HOCPNFDN_02605 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
HOCPNFDN_02607 7.7e-163 gltR K LysR substrate binding domain
HOCPNFDN_02608 1.3e-66 yodA S tautomerase
HOCPNFDN_02609 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
HOCPNFDN_02610 2e-199 trkA P Oxidoreductase
HOCPNFDN_02611 5.9e-160 yrdQ K Transcriptional regulator
HOCPNFDN_02612 1.7e-171 yrdR EG EamA-like transporter family
HOCPNFDN_02613 2.1e-17 S YrzO-like protein
HOCPNFDN_02614 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HOCPNFDN_02615 1.4e-83 bltD 2.3.1.57 K FR47-like protein
HOCPNFDN_02616 3.5e-211 blt EGP Major facilitator Superfamily
HOCPNFDN_02617 4.8e-151 bltR K helix_turn_helix, mercury resistance
HOCPNFDN_02618 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOCPNFDN_02619 3.3e-71 ywhA K Transcriptional regulator
HOCPNFDN_02620 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HOCPNFDN_02621 5.1e-119 ywhC S Peptidase family M50
HOCPNFDN_02622 5.2e-95 ywhD S YwhD family
HOCPNFDN_02623 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HOCPNFDN_02624 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HOCPNFDN_02625 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HOCPNFDN_02626 1e-84 ywhH S Aminoacyl-tRNA editing domain
HOCPNFDN_02628 2.3e-79 S aspartate phosphatase
HOCPNFDN_02629 2.5e-205 ywhK CO amine dehydrogenase activity
HOCPNFDN_02630 2.9e-249 ywhL CO amine dehydrogenase activity
HOCPNFDN_02632 1.2e-249 L Peptidase, M16
HOCPNFDN_02633 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
HOCPNFDN_02634 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HOCPNFDN_02635 3.3e-132 cbiO V ABC transporter
HOCPNFDN_02637 2.6e-271 C Fe-S oxidoreductases
HOCPNFDN_02638 1e-07 S Bacteriocin subtilosin A
HOCPNFDN_02639 4.7e-73 ywiB S protein conserved in bacteria
HOCPNFDN_02640 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HOCPNFDN_02641 9.8e-214 narK P COG2223 Nitrate nitrite transporter
HOCPNFDN_02642 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
HOCPNFDN_02643 4.3e-140 ywiC S YwiC-like protein
HOCPNFDN_02644 7e-86 arfM T cyclic nucleotide binding
HOCPNFDN_02645 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HOCPNFDN_02646 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
HOCPNFDN_02647 2.4e-98 narJ 1.7.5.1 C nitrate reductase
HOCPNFDN_02648 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
HOCPNFDN_02649 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOCPNFDN_02650 0.0 ywjA V ABC transporter
HOCPNFDN_02651 4.8e-96 ywjB H RibD C-terminal domain
HOCPNFDN_02652 2.7e-42 ywjC
HOCPNFDN_02653 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HOCPNFDN_02654 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HOCPNFDN_02655 0.0 fadF C COG0247 Fe-S oxidoreductase
HOCPNFDN_02656 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HOCPNFDN_02657 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HOCPNFDN_02658 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HOCPNFDN_02659 2.4e-92 ywjG S Domain of unknown function (DUF2529)
HOCPNFDN_02660 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HOCPNFDN_02661 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HOCPNFDN_02662 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HOCPNFDN_02663 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOCPNFDN_02664 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HOCPNFDN_02665 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HOCPNFDN_02666 1.1e-32 rpmE J Binds the 23S rRNA
HOCPNFDN_02667 2.4e-104 tdk 2.7.1.21 F thymidine kinase
HOCPNFDN_02668 0.0 sfcA 1.1.1.38 C malic enzyme
HOCPNFDN_02669 8.6e-160 ywkB S Membrane transport protein
HOCPNFDN_02670 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HOCPNFDN_02671 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOCPNFDN_02672 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HOCPNFDN_02673 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HOCPNFDN_02675 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
HOCPNFDN_02676 6.1e-112 spoIIR S stage II sporulation protein R
HOCPNFDN_02677 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HOCPNFDN_02678 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HOCPNFDN_02679 1.7e-91 mntP P Probably functions as a manganese efflux pump
HOCPNFDN_02680 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOCPNFDN_02681 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HOCPNFDN_02682 7.2e-95 ywlG S Belongs to the UPF0340 family
HOCPNFDN_02683 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOCPNFDN_02684 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HOCPNFDN_02685 2.5e-62 atpI S ATP synthase
HOCPNFDN_02686 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HOCPNFDN_02687 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOCPNFDN_02688 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HOCPNFDN_02689 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOCPNFDN_02690 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HOCPNFDN_02691 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HOCPNFDN_02692 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HOCPNFDN_02693 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HOCPNFDN_02694 4.3e-88 ywmA
HOCPNFDN_02695 1.3e-32 ywzB S membrane
HOCPNFDN_02696 1.6e-134 ywmB S TATA-box binding
HOCPNFDN_02697 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOCPNFDN_02698 2e-178 spoIID D Stage II sporulation protein D
HOCPNFDN_02699 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HOCPNFDN_02700 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HOCPNFDN_02702 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HOCPNFDN_02703 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HOCPNFDN_02704 1.3e-103 S response regulator aspartate phosphatase
HOCPNFDN_02705 3e-84 ywmF S Peptidase M50
HOCPNFDN_02706 3.8e-11 csbD K CsbD-like
HOCPNFDN_02708 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HOCPNFDN_02709 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HOCPNFDN_02710 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HOCPNFDN_02711 1.7e-64 ywnA K Transcriptional regulator
HOCPNFDN_02712 1.6e-114 ywnB S NAD(P)H-binding
HOCPNFDN_02713 2.6e-59 ywnC S Family of unknown function (DUF5362)
HOCPNFDN_02714 4.1e-144 mta K transcriptional
HOCPNFDN_02715 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOCPNFDN_02716 2.2e-70 ywnF S Family of unknown function (DUF5392)
HOCPNFDN_02717 2.7e-14 ywnC S Family of unknown function (DUF5362)
HOCPNFDN_02718 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HOCPNFDN_02719 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HOCPNFDN_02720 3.5e-73 ywnJ S VanZ like family
HOCPNFDN_02721 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HOCPNFDN_02722 1.6e-58 nrgB K Belongs to the P(II) protein family
HOCPNFDN_02723 2.5e-225 amt P Ammonium transporter
HOCPNFDN_02724 1.2e-77
HOCPNFDN_02725 4e-104 phzA Q Isochorismatase family
HOCPNFDN_02726 4.4e-242 ywoD EGP Major facilitator superfamily
HOCPNFDN_02727 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HOCPNFDN_02728 1.2e-231 ywoF P Right handed beta helix region
HOCPNFDN_02729 2.7e-211 ywoG EGP Major facilitator Superfamily
HOCPNFDN_02730 2.1e-70 ywoH K COG1846 Transcriptional regulators
HOCPNFDN_02731 3e-44 spoIIID K Stage III sporulation protein D
HOCPNFDN_02732 3.5e-180 mbl D Rod shape-determining protein
HOCPNFDN_02733 6.9e-126 flhO N flagellar basal body
HOCPNFDN_02734 1.5e-141 flhP N flagellar basal body
HOCPNFDN_02735 2.1e-199 S aspartate phosphatase
HOCPNFDN_02736 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HOCPNFDN_02737 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HOCPNFDN_02738 1.9e-153 ywpD T Histidine kinase
HOCPNFDN_02739 8e-51 srtA 3.4.22.70 M Sortase family
HOCPNFDN_02740 1.1e-66 ywpF S YwpF-like protein
HOCPNFDN_02741 1.3e-66 ywpG
HOCPNFDN_02742 9.8e-58 ssbB L Single-stranded DNA-binding protein
HOCPNFDN_02743 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HOCPNFDN_02744 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HOCPNFDN_02745 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HOCPNFDN_02746 3.8e-309 ywqB S SWIM zinc finger
HOCPNFDN_02747 1.2e-17
HOCPNFDN_02748 2e-116 ywqC M biosynthesis protein
HOCPNFDN_02749 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HOCPNFDN_02750 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HOCPNFDN_02751 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HOCPNFDN_02752 3.4e-154 ywqG S Domain of unknown function (DUF1963)
HOCPNFDN_02753 3.3e-15 S Domain of unknown function (DUF5082)
HOCPNFDN_02754 1.3e-38 ywqI S Family of unknown function (DUF5344)
HOCPNFDN_02755 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
HOCPNFDN_02756 1.7e-52 S MORN repeat variant
HOCPNFDN_02757 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HOCPNFDN_02758 2.9e-162 K Transcriptional regulator
HOCPNFDN_02759 2.7e-102 ywqN S NAD(P)H-dependent
HOCPNFDN_02761 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
HOCPNFDN_02762 2.4e-104 ywrB P Chromate transporter
HOCPNFDN_02763 2.1e-82 ywrC K Transcriptional regulator
HOCPNFDN_02764 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HOCPNFDN_02765 2.9e-54 S Domain of unknown function (DUF4181)
HOCPNFDN_02766 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HOCPNFDN_02767 3.7e-12
HOCPNFDN_02768 1.2e-210 cotH M Spore Coat
HOCPNFDN_02769 7.6e-131 cotB
HOCPNFDN_02770 7.5e-126 ywrJ
HOCPNFDN_02771 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HOCPNFDN_02772 1.1e-169 alsR K LysR substrate binding domain
HOCPNFDN_02773 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HOCPNFDN_02774 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HOCPNFDN_02775 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HOCPNFDN_02776 3.6e-48 ywsA S Protein of unknown function (DUF3892)
HOCPNFDN_02777 4.6e-94 batE T Sh3 type 3 domain protein
HOCPNFDN_02778 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HOCPNFDN_02779 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HOCPNFDN_02780 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HOCPNFDN_02781 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HOCPNFDN_02782 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOCPNFDN_02783 1.9e-178 rbsR K transcriptional
HOCPNFDN_02784 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HOCPNFDN_02785 8.6e-70 pgsC S biosynthesis protein
HOCPNFDN_02786 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HOCPNFDN_02787 3.6e-21 ywtC
HOCPNFDN_02788 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HOCPNFDN_02789 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HOCPNFDN_02790 8.4e-171 ywtF K Transcriptional regulator
HOCPNFDN_02791 1.9e-248 ywtG EGP Major facilitator Superfamily
HOCPNFDN_02792 7.6e-216 gerAC S Spore germination protein
HOCPNFDN_02793 7.5e-200 gerBB E Spore germination protein
HOCPNFDN_02794 3.5e-266 gerBA EG Spore germination protein
HOCPNFDN_02795 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HOCPNFDN_02796 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HOCPNFDN_02797 1.2e-260
HOCPNFDN_02798 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HOCPNFDN_02799 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HOCPNFDN_02800 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HOCPNFDN_02801 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HOCPNFDN_02802 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HOCPNFDN_02803 1.1e-150 tagG GM Transport permease protein
HOCPNFDN_02804 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HOCPNFDN_02805 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HOCPNFDN_02807 8.1e-257 ggaA M Glycosyltransferase like family 2
HOCPNFDN_02808 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOCPNFDN_02809 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HOCPNFDN_02810 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HOCPNFDN_02811 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HOCPNFDN_02812 6e-38
HOCPNFDN_02813 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HOCPNFDN_02814 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HOCPNFDN_02815 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HOCPNFDN_02816 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOCPNFDN_02817 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HOCPNFDN_02818 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HOCPNFDN_02819 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
HOCPNFDN_02820 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
HOCPNFDN_02821 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HOCPNFDN_02822 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HOCPNFDN_02823 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HOCPNFDN_02824 6e-163 yvhJ K Transcriptional regulator
HOCPNFDN_02825 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HOCPNFDN_02826 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HOCPNFDN_02827 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOCPNFDN_02828 7.3e-155 degV S protein conserved in bacteria
HOCPNFDN_02829 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HOCPNFDN_02830 5.7e-46 comFB S Late competence development protein ComFB
HOCPNFDN_02831 2.7e-129 comFC S Phosphoribosyl transferase domain
HOCPNFDN_02832 7e-74 yvyF S flagellar protein
HOCPNFDN_02833 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
HOCPNFDN_02834 2.4e-78 flgN NOU FlgN protein
HOCPNFDN_02835 1.2e-264 flgK N flagellar hook-associated protein
HOCPNFDN_02836 1.1e-156 flgL N Belongs to the bacterial flagellin family
HOCPNFDN_02837 2.6e-50 yviE
HOCPNFDN_02838 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HOCPNFDN_02839 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HOCPNFDN_02840 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HOCPNFDN_02841 6.1e-57 flaG N flagellar protein FlaG
HOCPNFDN_02842 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HOCPNFDN_02843 2.9e-69 fliS N flagellar protein FliS
HOCPNFDN_02844 1.9e-08 fliT S bacterial-type flagellum organization
HOCPNFDN_02845 2.8e-66
HOCPNFDN_02846 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOCPNFDN_02847 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HOCPNFDN_02848 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HOCPNFDN_02849 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HOCPNFDN_02850 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HOCPNFDN_02851 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HOCPNFDN_02852 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HOCPNFDN_02853 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HOCPNFDN_02854 5.3e-56 swrA S Swarming motility protein
HOCPNFDN_02855 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HOCPNFDN_02856 7.9e-228 yvkA EGP Major facilitator Superfamily
HOCPNFDN_02857 7e-101 yvkB K Transcriptional regulator
HOCPNFDN_02858 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HOCPNFDN_02859 1.2e-30 csbA S protein conserved in bacteria
HOCPNFDN_02860 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HOCPNFDN_02861 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HOCPNFDN_02862 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HOCPNFDN_02863 6.7e-34 yvkN
HOCPNFDN_02864 8e-49 yvlA
HOCPNFDN_02865 3.4e-168 yvlB S Putative adhesin
HOCPNFDN_02866 2.6e-26 pspB KT PspC domain
HOCPNFDN_02867 1.2e-50 yvlD S Membrane
HOCPNFDN_02868 2.7e-203 yvmA EGP Major facilitator Superfamily
HOCPNFDN_02869 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
HOCPNFDN_02870 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HOCPNFDN_02871 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
HOCPNFDN_02872 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
HOCPNFDN_02873 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HOCPNFDN_02874 3.6e-134 yvoA K transcriptional
HOCPNFDN_02875 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HOCPNFDN_02876 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HOCPNFDN_02877 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HOCPNFDN_02878 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HOCPNFDN_02879 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
HOCPNFDN_02880 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HOCPNFDN_02881 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HOCPNFDN_02882 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HOCPNFDN_02883 4.5e-140 yvpB NU protein conserved in bacteria
HOCPNFDN_02884 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HOCPNFDN_02885 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HOCPNFDN_02886 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HOCPNFDN_02887 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HOCPNFDN_02888 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOCPNFDN_02889 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HOCPNFDN_02890 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HOCPNFDN_02891 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HOCPNFDN_02892 4.6e-121
HOCPNFDN_02893 0.0
HOCPNFDN_02895 0.0 msbA2 3.6.3.44 V ABC transporter
HOCPNFDN_02896 2.4e-278 S COG0457 FOG TPR repeat
HOCPNFDN_02897 1.4e-102 usp CBM50 M protein conserved in bacteria
HOCPNFDN_02898 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HOCPNFDN_02899 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HOCPNFDN_02900 5.7e-166 rapZ S Displays ATPase and GTPase activities
HOCPNFDN_02901 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HOCPNFDN_02902 1.4e-170 whiA K May be required for sporulation
HOCPNFDN_02903 1.6e-36 crh G Phosphocarrier protein Chr
HOCPNFDN_02904 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HOCPNFDN_02905 1.8e-33
HOCPNFDN_02906 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_02907 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HOCPNFDN_02908 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HOCPNFDN_02909 0.0 yxdM V ABC transporter (permease)
HOCPNFDN_02910 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOCPNFDN_02911 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HOCPNFDN_02912 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HOCPNFDN_02913 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HOCPNFDN_02914 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HOCPNFDN_02915 3.6e-174 yvdE K Transcriptional regulator
HOCPNFDN_02916 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HOCPNFDN_02917 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HOCPNFDN_02918 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
HOCPNFDN_02919 7.8e-149 malD P transport
HOCPNFDN_02920 1.2e-158 malA S Protein of unknown function (DUF1189)
HOCPNFDN_02921 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HOCPNFDN_02922 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HOCPNFDN_02923 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HOCPNFDN_02924 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOCPNFDN_02926 1.5e-183 S Patatin-like phospholipase
HOCPNFDN_02927 9.2e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
HOCPNFDN_02928 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
HOCPNFDN_02929 4.1e-50 sugE P Small Multidrug Resistance protein
HOCPNFDN_02930 6.7e-51 ykkC P Small Multidrug Resistance protein
HOCPNFDN_02931 2.6e-106 yvdT K Transcriptional regulator
HOCPNFDN_02932 1.8e-295 yveA E amino acid
HOCPNFDN_02933 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HOCPNFDN_02934 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HOCPNFDN_02935 9.6e-266 pbpE V Beta-lactamase
HOCPNFDN_02936 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HOCPNFDN_02937 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
HOCPNFDN_02938 4.6e-93 padC Q Phenolic acid decarboxylase
HOCPNFDN_02940 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HOCPNFDN_02941 5.7e-77 slr K transcriptional
HOCPNFDN_02942 4e-122 ywqC M biosynthesis protein
HOCPNFDN_02943 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HOCPNFDN_02944 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HOCPNFDN_02945 2e-224 epsD GT4 M Glycosyl transferase 4-like
HOCPNFDN_02946 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HOCPNFDN_02947 5.3e-220 epsF GT4 M Glycosyl transferases group 1
HOCPNFDN_02948 4.8e-207 epsG S EpsG family
HOCPNFDN_02949 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
HOCPNFDN_02950 3.6e-207 epsI GM pyruvyl transferase
HOCPNFDN_02951 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HOCPNFDN_02952 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOCPNFDN_02953 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HOCPNFDN_02954 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HOCPNFDN_02955 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HOCPNFDN_02956 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
HOCPNFDN_02957 1e-31 yvfG S YvfG protein
HOCPNFDN_02958 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HOCPNFDN_02959 1.4e-309 yvfH C L-lactate permease
HOCPNFDN_02960 6.6e-111 yvfI K COG2186 Transcriptional regulators
HOCPNFDN_02961 1.8e-184 lacR K Transcriptional regulator
HOCPNFDN_02962 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
HOCPNFDN_02963 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HOCPNFDN_02964 3.2e-150 ganQ P transport
HOCPNFDN_02965 0.0 lacA 3.2.1.23 G beta-galactosidase
HOCPNFDN_02966 2.6e-252 galA 3.2.1.89 G arabinogalactan
HOCPNFDN_02967 1.4e-199 rsbU 3.1.3.3 T response regulator
HOCPNFDN_02968 2.6e-157 rsbQ S Alpha/beta hydrolase family
HOCPNFDN_02969 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HOCPNFDN_02970 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
HOCPNFDN_02971 8.9e-201 desK 2.7.13.3 T Histidine kinase
HOCPNFDN_02972 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOCPNFDN_02973 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HOCPNFDN_02974 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HOCPNFDN_02975 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HOCPNFDN_02976 4.3e-197 yvbX S Glycosyl hydrolase
HOCPNFDN_02977 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HOCPNFDN_02978 8.5e-157 yvbV EG EamA-like transporter family
HOCPNFDN_02979 3.9e-159 yvbU K Transcriptional regulator
HOCPNFDN_02980 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOCPNFDN_02981 5.5e-203 araR K transcriptional
HOCPNFDN_02982 1.6e-252 araE EGP Major facilitator Superfamily
HOCPNFDN_02983 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HOCPNFDN_02984 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOCPNFDN_02985 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HOCPNFDN_02986 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HOCPNFDN_02987 1.6e-84 ydcK S Belongs to the SprT family
HOCPNFDN_02988 0.0 yhgF K COG2183 Transcriptional accessory protein
HOCPNFDN_02989 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
HOCPNFDN_02990 1.5e-82 ydcG S EVE domain
HOCPNFDN_02994 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HOCPNFDN_02995 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOCPNFDN_02996 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HOCPNFDN_02997 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HOCPNFDN_02998 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HOCPNFDN_02999 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HOCPNFDN_03000 5.2e-57 rsbS T antagonist
HOCPNFDN_03001 1.3e-143 rsbR T Positive regulator of sigma-B
HOCPNFDN_03002 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HOCPNFDN_03003 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HOCPNFDN_03004 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOCPNFDN_03005 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HOCPNFDN_03006 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HOCPNFDN_03007 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HOCPNFDN_03008 2.2e-263 ydbT S Membrane
HOCPNFDN_03009 2.1e-82 ydbS S Bacterial PH domain
HOCPNFDN_03010 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HOCPNFDN_03011 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HOCPNFDN_03012 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HOCPNFDN_03013 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HOCPNFDN_03014 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOCPNFDN_03015 2.2e-07 S Fur-regulated basic protein A
HOCPNFDN_03016 1.1e-18 S Fur-regulated basic protein B
HOCPNFDN_03017 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HOCPNFDN_03018 2.7e-52 ydbL
HOCPNFDN_03019 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HOCPNFDN_03020 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
HOCPNFDN_03021 4.4e-181 ydbI S AI-2E family transporter
HOCPNFDN_03022 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOCPNFDN_03023 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
HOCPNFDN_03024 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HOCPNFDN_03025 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HOCPNFDN_03026 3.2e-155 ydbD P Catalase
HOCPNFDN_03027 2.8e-63 ydbC S Domain of unknown function (DUF4937
HOCPNFDN_03028 8.9e-59 ydbB G Cupin domain
HOCPNFDN_03030 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HOCPNFDN_03031 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HOCPNFDN_03033 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HOCPNFDN_03034 9.4e-40
HOCPNFDN_03035 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HOCPNFDN_03036 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HOCPNFDN_03037 0.0 ydaO E amino acid
HOCPNFDN_03038 0.0 ydaN S Bacterial cellulose synthase subunit
HOCPNFDN_03039 4.5e-233 ydaM M Glycosyl transferase family group 2
HOCPNFDN_03040 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HOCPNFDN_03041 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
HOCPNFDN_03042 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HOCPNFDN_03043 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOCPNFDN_03044 2.5e-74 lrpC K Transcriptional regulator
HOCPNFDN_03045 5.1e-47 ydzA EGP Major facilitator Superfamily
HOCPNFDN_03046 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HOCPNFDN_03047 6.8e-77 ydaG 1.4.3.5 S general stress protein
HOCPNFDN_03048 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HOCPNFDN_03049 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HOCPNFDN_03050 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOCPNFDN_03051 1.1e-99 ydaC Q Methyltransferase domain
HOCPNFDN_03052 1.4e-294 ydaB IQ acyl-CoA ligase
HOCPNFDN_03053 0.0 mtlR K transcriptional regulator, MtlR
HOCPNFDN_03054 2.8e-176 ydhF S Oxidoreductase
HOCPNFDN_03055 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HOCPNFDN_03056 1.4e-49 yczJ S biosynthesis
HOCPNFDN_03058 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
HOCPNFDN_03059 1.2e-132 kipR K Transcriptional regulator
HOCPNFDN_03060 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HOCPNFDN_03061 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HOCPNFDN_03062 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
HOCPNFDN_03063 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HOCPNFDN_03064 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
HOCPNFDN_03065 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HOCPNFDN_03067 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HOCPNFDN_03068 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HOCPNFDN_03069 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HOCPNFDN_03070 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HOCPNFDN_03071 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HOCPNFDN_03072 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HOCPNFDN_03073 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HOCPNFDN_03074 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HOCPNFDN_03075 7.3e-56
HOCPNFDN_03076 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HOCPNFDN_03077 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
HOCPNFDN_03078 1.3e-100 ycnI S protein conserved in bacteria
HOCPNFDN_03079 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOCPNFDN_03080 6.1e-149 glcU U Glucose uptake
HOCPNFDN_03081 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HOCPNFDN_03082 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOCPNFDN_03083 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOCPNFDN_03084 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HOCPNFDN_03085 1.6e-45 ycnE S Monooxygenase
HOCPNFDN_03086 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HOCPNFDN_03087 6.5e-154 ycnC K Transcriptional regulator
HOCPNFDN_03088 1.4e-251 ycnB EGP Major facilitator Superfamily
HOCPNFDN_03089 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HOCPNFDN_03090 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HOCPNFDN_03091 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_03092 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_03093 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
HOCPNFDN_03096 5.2e-71 S aspartate phosphatase
HOCPNFDN_03097 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HOCPNFDN_03098 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_03099 1.7e-204 yclI V ABC transporter (permease) YclI
HOCPNFDN_03100 3.9e-122 yclH P ABC transporter
HOCPNFDN_03101 9.9e-200 gerKB F Spore germination protein
HOCPNFDN_03102 1.3e-232 gerKC S spore germination
HOCPNFDN_03103 6.8e-282 gerKA EG Spore germination protein
HOCPNFDN_03105 2.9e-310 yclG M Pectate lyase superfamily protein
HOCPNFDN_03106 1.5e-267 dtpT E amino acid peptide transporter
HOCPNFDN_03107 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
HOCPNFDN_03108 1.1e-83 yclD
HOCPNFDN_03109 4e-39 bsdD 4.1.1.61 S response to toxic substance
HOCPNFDN_03110 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HOCPNFDN_03111 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HOCPNFDN_03112 4.9e-162 bsdA K LysR substrate binding domain
HOCPNFDN_03113 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HOCPNFDN_03114 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HOCPNFDN_03115 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HOCPNFDN_03116 4.4e-115 yczE S membrane
HOCPNFDN_03117 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HOCPNFDN_03118 4.4e-255 ycxD K GntR family transcriptional regulator
HOCPNFDN_03119 7.4e-164 ycxC EG EamA-like transporter family
HOCPNFDN_03120 4.9e-91 S YcxB-like protein
HOCPNFDN_03121 4.2e-228 EGP Major Facilitator Superfamily
HOCPNFDN_03122 5.7e-140 srfAD Q thioesterase
HOCPNFDN_03123 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HOCPNFDN_03124 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCPNFDN_03125 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCPNFDN_03126 1.3e-63 hxlR K transcriptional
HOCPNFDN_03127 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HOCPNFDN_03128 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HOCPNFDN_03129 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
HOCPNFDN_03130 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
HOCPNFDN_03131 3.4e-70 nin S Competence protein J (ComJ)
HOCPNFDN_03132 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HOCPNFDN_03133 3.5e-52 yckD S Protein of unknown function (DUF2680)
HOCPNFDN_03134 3.3e-77 yckC S membrane
HOCPNFDN_03137 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HOCPNFDN_03138 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
HOCPNFDN_03139 1.4e-228 yciC S GTPases (G3E family)
HOCPNFDN_03140 5.5e-109 yciB M ErfK YbiS YcfS YnhG
HOCPNFDN_03141 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HOCPNFDN_03142 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
HOCPNFDN_03143 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HOCPNFDN_03144 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HOCPNFDN_03145 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HOCPNFDN_03146 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HOCPNFDN_03147 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HOCPNFDN_03148 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HOCPNFDN_03149 5.7e-163 I alpha/beta hydrolase fold
HOCPNFDN_03150 1.2e-139 ycgR S permeases
HOCPNFDN_03151 2.6e-147 ycgQ S membrane
HOCPNFDN_03152 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HOCPNFDN_03153 1.3e-76 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOCPNFDN_03154 5.1e-149 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOCPNFDN_03155 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HOCPNFDN_03156 5.1e-170 ycgM E Proline dehydrogenase
HOCPNFDN_03157 2.9e-145 ycgL S Predicted nucleotidyltransferase
HOCPNFDN_03158 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HOCPNFDN_03159 2.2e-179 oxyR3 K LysR substrate binding domain
HOCPNFDN_03160 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
HOCPNFDN_03161 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HOCPNFDN_03162 2.5e-109 tmrB S AAA domain
HOCPNFDN_03163 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HOCPNFDN_03164 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HOCPNFDN_03165 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HOCPNFDN_03166 1.2e-151 yqcI S YqcI/YcgG family
HOCPNFDN_03167 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HOCPNFDN_03168 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HOCPNFDN_03169 6.2e-269 mdr EGP Major facilitator Superfamily
HOCPNFDN_03170 6.5e-293 lctP C L-lactate permease
HOCPNFDN_03171 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HOCPNFDN_03172 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HOCPNFDN_03173 1.1e-98 ycgB
HOCPNFDN_03174 1e-257 ycgA S Membrane
HOCPNFDN_03175 1.2e-219 amhX S amidohydrolase
HOCPNFDN_03176 5.3e-164 opuAC E glycine betaine
HOCPNFDN_03177 1.3e-127 opuAB P glycine betaine
HOCPNFDN_03178 5.1e-229 proV 3.6.3.32 E glycine betaine
HOCPNFDN_03179 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HOCPNFDN_03180 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
HOCPNFDN_03181 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
HOCPNFDN_03182 2e-192 yceH P Belongs to the TelA family
HOCPNFDN_03183 0.0 yceG S Putative component of 'biosynthetic module'
HOCPNFDN_03184 6.3e-137 terC P Protein of unknown function (DUF475)
HOCPNFDN_03185 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HOCPNFDN_03186 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HOCPNFDN_03187 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HOCPNFDN_03188 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOCPNFDN_03189 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HOCPNFDN_03190 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HOCPNFDN_03191 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
HOCPNFDN_03192 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HOCPNFDN_03193 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
HOCPNFDN_03194 5.5e-174 S response regulator aspartate phosphatase
HOCPNFDN_03195 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
HOCPNFDN_03196 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HOCPNFDN_03197 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HOCPNFDN_03198 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HOCPNFDN_03199 1.6e-174 yccK C Aldo keto reductase
HOCPNFDN_03200 4.5e-203 natB CP ABC-2 family transporter protein
HOCPNFDN_03201 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HOCPNFDN_03202 1.2e-126 lytR_2 T LytTr DNA-binding domain
HOCPNFDN_03203 2e-161 2.7.13.3 T GHKL domain
HOCPNFDN_03204 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
HOCPNFDN_03205 2e-59 S RDD family
HOCPNFDN_03206 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HOCPNFDN_03207 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HOCPNFDN_03208 4.8e-102 yxaF K Transcriptional regulator
HOCPNFDN_03209 5.8e-229 lmrB EGP the major facilitator superfamily
HOCPNFDN_03210 6.2e-210 ycbU E Selenocysteine lyase
HOCPNFDN_03211 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HOCPNFDN_03212 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HOCPNFDN_03213 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HOCPNFDN_03214 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HOCPNFDN_03215 6.6e-136 ycbR T vWA found in TerF C terminus
HOCPNFDN_03216 1.3e-78 sleB 3.5.1.28 M Cell wall
HOCPNFDN_03217 8.2e-53 ycbP S Protein of unknown function (DUF2512)
HOCPNFDN_03218 2.1e-115 S ABC-2 family transporter protein
HOCPNFDN_03219 4.8e-168 ycbN V ABC transporter, ATP-binding protein
HOCPNFDN_03220 2.4e-170 T PhoQ Sensor
HOCPNFDN_03221 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_03222 7.3e-172 eamA1 EG spore germination
HOCPNFDN_03223 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HOCPNFDN_03224 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
HOCPNFDN_03225 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
HOCPNFDN_03226 1.5e-124 ycbG K FCD
HOCPNFDN_03227 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HOCPNFDN_03228 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HOCPNFDN_03229 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HOCPNFDN_03230 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HOCPNFDN_03231 9e-170 glnL T Regulator
HOCPNFDN_03232 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
HOCPNFDN_03233 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
HOCPNFDN_03234 2.3e-257 agcS E Sodium alanine symporter
HOCPNFDN_03235 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HOCPNFDN_03236 6.7e-262 mmuP E amino acid
HOCPNFDN_03237 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HOCPNFDN_03239 4.9e-128 K UTRA
HOCPNFDN_03240 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HOCPNFDN_03241 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOCPNFDN_03242 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOCPNFDN_03243 3.9e-192 yceA S Belongs to the UPF0176 family
HOCPNFDN_03244 6.7e-167 ybfP K Transcriptional regulator
HOCPNFDN_03245 4.3e-258 S Erythromycin esterase
HOCPNFDN_03246 3.2e-46 ybfN
HOCPNFDN_03247 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HOCPNFDN_03248 2.7e-85 ybfM S SNARE associated Golgi protein
HOCPNFDN_03249 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOCPNFDN_03250 2.5e-169 S Alpha/beta hydrolase family
HOCPNFDN_03252 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HOCPNFDN_03253 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HOCPNFDN_03254 2.3e-145 msmR K AraC-like ligand binding domain
HOCPNFDN_03255 8.8e-162 ybfH EG EamA-like transporter family
HOCPNFDN_03256 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HOCPNFDN_03258 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
HOCPNFDN_03259 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
HOCPNFDN_03260 2.9e-35 S Protein of unknown function (DUF2651)
HOCPNFDN_03261 7.3e-258 glpT G -transporter
HOCPNFDN_03262 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HOCPNFDN_03263 1.8e-290 ybeC E amino acid
HOCPNFDN_03264 4.9e-41 ybyB
HOCPNFDN_03265 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HOCPNFDN_03266 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
HOCPNFDN_03267 4.9e-30 ybxH S Family of unknown function (DUF5370)
HOCPNFDN_03268 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HOCPNFDN_03269 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HOCPNFDN_03270 1.5e-217 ybdO S Domain of unknown function (DUF4885)
HOCPNFDN_03271 4.8e-154 ybdN
HOCPNFDN_03272 1.6e-140 KLT Protein tyrosine kinase
HOCPNFDN_03274 1.8e-173 T His Kinase A (phospho-acceptor) domain
HOCPNFDN_03275 1.5e-123 T Transcriptional regulatory protein, C terminal
HOCPNFDN_03276 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HOCPNFDN_03277 9.6e-79 txn CO Thioredoxin-like
HOCPNFDN_03278 7.8e-91 C HEAT repeats
HOCPNFDN_03279 4e-248 skfF S ABC transporter
HOCPNFDN_03280 1.9e-135 skfE V ABC transporter
HOCPNFDN_03281 1.6e-277 V CAAX protease self-immunity
HOCPNFDN_03282 9.1e-239 J 4Fe-4S single cluster domain
HOCPNFDN_03284 2e-203 ybcL EGP Major facilitator Superfamily
HOCPNFDN_03285 5.1e-50 ybzH K Helix-turn-helix domain
HOCPNFDN_03286 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HOCPNFDN_03287 3.9e-47
HOCPNFDN_03288 3.7e-96 can 4.2.1.1 P carbonic anhydrase
HOCPNFDN_03289 0.0 ybcC S Belongs to the UPF0753 family
HOCPNFDN_03290 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HOCPNFDN_03291 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HOCPNFDN_03292 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
HOCPNFDN_03293 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HOCPNFDN_03294 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HOCPNFDN_03295 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOCPNFDN_03296 3e-225 ybbR S protein conserved in bacteria
HOCPNFDN_03297 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HOCPNFDN_03298 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HOCPNFDN_03299 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HOCPNFDN_03305 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HOCPNFDN_03306 6.4e-87 ybbJ J acetyltransferase
HOCPNFDN_03307 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HOCPNFDN_03308 1.1e-150 ybbH K transcriptional
HOCPNFDN_03309 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOCPNFDN_03310 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HOCPNFDN_03311 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HOCPNFDN_03312 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
HOCPNFDN_03313 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HOCPNFDN_03314 7.2e-167 feuA P Iron-uptake system-binding protein
HOCPNFDN_03315 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_03316 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_03317 2.2e-142 ybbA S Putative esterase
HOCPNFDN_03318 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
HOCPNFDN_03320 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HOCPNFDN_03321 6.7e-167 ygxA S Nucleotidyltransferase-like
HOCPNFDN_03322 1.5e-56 ygzB S UPF0295 protein
HOCPNFDN_03323 4e-80 perR P Belongs to the Fur family
HOCPNFDN_03324 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
HOCPNFDN_03325 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HOCPNFDN_03326 8.7e-180 ygaE S Membrane
HOCPNFDN_03327 1.8e-301 ygaD V ABC transporter
HOCPNFDN_03328 1.3e-104 ygaC J Belongs to the UPF0374 family
HOCPNFDN_03329 4.9e-48 ygaB S YgaB-like protein
HOCPNFDN_03330 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HOCPNFDN_03331 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOCPNFDN_03332 6.9e-36 yfhS
HOCPNFDN_03333 7.8e-212 mutY L A G-specific
HOCPNFDN_03334 5.5e-186 yfhP S membrane-bound metal-dependent
HOCPNFDN_03335 0.0 yfhO S Bacterial membrane protein YfhO
HOCPNFDN_03336 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HOCPNFDN_03337 6.7e-172 yfhM S Alpha beta hydrolase
HOCPNFDN_03338 3.5e-51 yfhL S SdpI/YhfL protein family
HOCPNFDN_03339 9.2e-92 batE T Bacterial SH3 domain homologues
HOCPNFDN_03340 1.3e-44 yfhJ S WVELL protein
HOCPNFDN_03341 6.2e-20 sspK S reproduction
HOCPNFDN_03342 1.1e-209 yfhI EGP Major facilitator Superfamily
HOCPNFDN_03344 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HOCPNFDN_03345 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HOCPNFDN_03346 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
HOCPNFDN_03348 2.1e-25 yfhD S YfhD-like protein
HOCPNFDN_03349 3.9e-107 yfhC C nitroreductase
HOCPNFDN_03350 1.8e-167 yfhB 5.3.3.17 S PhzF family
HOCPNFDN_03351 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_03352 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_03353 6.2e-182 yfiY P ABC transporter substrate-binding protein
HOCPNFDN_03354 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HOCPNFDN_03355 3.1e-81 yfiV K transcriptional
HOCPNFDN_03356 8.7e-287 yfiU EGP Major facilitator Superfamily
HOCPNFDN_03357 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
HOCPNFDN_03358 5.1e-221 yfiS EGP Major facilitator Superfamily
HOCPNFDN_03359 2e-109 yfiR K Transcriptional regulator
HOCPNFDN_03360 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HOCPNFDN_03361 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HOCPNFDN_03362 8.3e-99 padR K transcriptional
HOCPNFDN_03363 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
HOCPNFDN_03364 9.8e-214 V ABC-2 family transporter protein
HOCPNFDN_03365 6.2e-171 V ABC transporter, ATP-binding protein
HOCPNFDN_03366 3.2e-113 KT LuxR family transcriptional regulator
HOCPNFDN_03367 1.1e-214 yxjM T Histidine kinase
HOCPNFDN_03369 1.1e-233 S Oxidoreductase
HOCPNFDN_03370 8.4e-184 G Xylose isomerase
HOCPNFDN_03371 1.8e-262 iolT EGP Major facilitator Superfamily
HOCPNFDN_03372 1.5e-177 K AraC-like ligand binding domain
HOCPNFDN_03373 5.7e-163 yfiE 1.13.11.2 S glyoxalase
HOCPNFDN_03374 9.8e-65 mhqP S DoxX
HOCPNFDN_03375 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HOCPNFDN_03376 2.1e-310 yfiB3 V ABC transporter
HOCPNFDN_03377 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOCPNFDN_03378 2.1e-140 glvR K Helix-turn-helix domain, rpiR family
HOCPNFDN_03379 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HOCPNFDN_03380 1.1e-44 yfjA S Belongs to the WXG100 family
HOCPNFDN_03381 9.2e-191 yfjB
HOCPNFDN_03382 4.1e-144 yfjC
HOCPNFDN_03383 1.8e-101 yfjD S Family of unknown function (DUF5381)
HOCPNFDN_03384 1.3e-80 S Family of unknown function (DUF5381)
HOCPNFDN_03385 4e-56 yfjF S UPF0060 membrane protein
HOCPNFDN_03386 1.2e-25 sspH S Belongs to the SspH family
HOCPNFDN_03387 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HOCPNFDN_03388 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HOCPNFDN_03389 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HOCPNFDN_03390 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HOCPNFDN_03391 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HOCPNFDN_03392 3e-29 yfjL
HOCPNFDN_03393 3.9e-86 yfjM S Psort location Cytoplasmic, score
HOCPNFDN_03394 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOCPNFDN_03395 1.6e-39 S YfzA-like protein
HOCPNFDN_03396 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOCPNFDN_03397 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HOCPNFDN_03398 1.7e-184 corA P Mediates influx of magnesium ions
HOCPNFDN_03399 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HOCPNFDN_03400 2.6e-154 pdaA G deacetylase
HOCPNFDN_03401 1.1e-26 yfjT
HOCPNFDN_03402 5.4e-222 yfkA S YfkB-like domain
HOCPNFDN_03403 6e-149 yfkC M Mechanosensitive ion channel
HOCPNFDN_03404 1.2e-146 yfkD S YfkD-like protein
HOCPNFDN_03405 6.1e-183 cax P COG0387 Ca2 H antiporter
HOCPNFDN_03406 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HOCPNFDN_03407 5e-08
HOCPNFDN_03408 9.7e-144 yihY S Belongs to the UPF0761 family
HOCPNFDN_03409 8.4e-51 yfkI S gas vesicle protein
HOCPNFDN_03410 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOCPNFDN_03411 2.1e-29 yfkK S Belongs to the UPF0435 family
HOCPNFDN_03412 6.8e-207 ydiM EGP Major facilitator Superfamily
HOCPNFDN_03413 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HOCPNFDN_03414 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HOCPNFDN_03415 1.6e-125 yfkO C nitroreductase
HOCPNFDN_03416 1.8e-133 treR K transcriptional
HOCPNFDN_03417 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HOCPNFDN_03418 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOCPNFDN_03419 1.5e-283 yfkQ EG Spore germination protein
HOCPNFDN_03420 5.1e-207 yfkR S spore germination
HOCPNFDN_03422 1.6e-194 E Spore germination protein
HOCPNFDN_03423 3.2e-256 agcS_1 E Sodium alanine symporter
HOCPNFDN_03424 6e-67 yhdN S Domain of unknown function (DUF1992)
HOCPNFDN_03425 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HOCPNFDN_03426 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HOCPNFDN_03427 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HOCPNFDN_03428 2.4e-50 yflH S Protein of unknown function (DUF3243)
HOCPNFDN_03429 4.1e-19 yflI
HOCPNFDN_03430 4e-18 yflJ S Protein of unknown function (DUF2639)
HOCPNFDN_03431 9e-124 yflK S protein conserved in bacteria
HOCPNFDN_03432 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HOCPNFDN_03433 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HOCPNFDN_03434 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HOCPNFDN_03435 8.5e-227 citM C Citrate transporter
HOCPNFDN_03437 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
HOCPNFDN_03438 8.9e-119 citT T response regulator
HOCPNFDN_03439 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HOCPNFDN_03440 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
HOCPNFDN_03441 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HOCPNFDN_03442 7.6e-58 yflT S Heat induced stress protein YflT
HOCPNFDN_03443 2.9e-24 S Protein of unknown function (DUF3212)
HOCPNFDN_03444 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HOCPNFDN_03445 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_03446 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOCPNFDN_03447 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HOCPNFDN_03448 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
HOCPNFDN_03449 7.7e-214 G Major Facilitator Superfamily
HOCPNFDN_03450 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
HOCPNFDN_03451 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
HOCPNFDN_03452 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HOCPNFDN_03453 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HOCPNFDN_03454 1.5e-209 yfmO EGP Major facilitator Superfamily
HOCPNFDN_03455 2.8e-70 yfmP K transcriptional
HOCPNFDN_03456 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
HOCPNFDN_03457 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HOCPNFDN_03458 1.1e-113 yfmS NT chemotaxis protein
HOCPNFDN_03459 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HOCPNFDN_03460 1.3e-241 yfnA E amino acid
HOCPNFDN_03461 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HOCPNFDN_03462 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
HOCPNFDN_03463 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
HOCPNFDN_03464 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HOCPNFDN_03465 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
HOCPNFDN_03466 1.9e-172 yfnG 4.2.1.45 M dehydratase
HOCPNFDN_03467 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
HOCPNFDN_03468 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HOCPNFDN_03469 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HOCPNFDN_03470 3.6e-199 yetN S Protein of unknown function (DUF3900)
HOCPNFDN_03471 7.8e-213 yetM CH FAD binding domain
HOCPNFDN_03472 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HOCPNFDN_03473 5.4e-159 yetK EG EamA-like transporter family
HOCPNFDN_03474 5.3e-105 yetJ S Belongs to the BI1 family
HOCPNFDN_03475 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HOCPNFDN_03476 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HOCPNFDN_03477 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HOCPNFDN_03478 2.2e-34
HOCPNFDN_03479 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOCPNFDN_03480 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HOCPNFDN_03481 6.1e-123 yetF S membrane
HOCPNFDN_03482 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HOCPNFDN_03483 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HOCPNFDN_03484 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HOCPNFDN_03485 9.6e-291 lplA G Bacterial extracellular solute-binding protein
HOCPNFDN_03486 0.0 yetA
HOCPNFDN_03487 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HOCPNFDN_03488 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
HOCPNFDN_03489 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HOCPNFDN_03490 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HOCPNFDN_03491 1e-113 yesV S Protein of unknown function, DUF624
HOCPNFDN_03492 8.9e-132 yesU S Domain of unknown function (DUF1961)
HOCPNFDN_03493 3.8e-133 E GDSL-like Lipase/Acylhydrolase
HOCPNFDN_03494 0.0 yesS K Transcriptional regulator
HOCPNFDN_03495 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HOCPNFDN_03496 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
HOCPNFDN_03497 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HOCPNFDN_03498 5e-248 yesO G Bacterial extracellular solute-binding protein
HOCPNFDN_03499 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
HOCPNFDN_03500 0.0 yesM 2.7.13.3 T Histidine kinase
HOCPNFDN_03501 4.4e-104 yesL S Protein of unknown function, DUF624
HOCPNFDN_03503 4.2e-103 yesJ K Acetyltransferase (GNAT) family
HOCPNFDN_03504 5.2e-104 cotJC P Spore Coat
HOCPNFDN_03505 1.5e-45 cotJB S CotJB protein
HOCPNFDN_03506 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HOCPNFDN_03507 2.2e-159 yesF GM NAD(P)H-binding
HOCPNFDN_03508 9.7e-82 yesE S SnoaL-like domain
HOCPNFDN_03509 1.2e-103 dhaR3 K Transcriptional regulator
HOCPNFDN_03511 9.4e-127 yeeN K transcriptional regulatory protein
HOCPNFDN_03513 5.5e-214 S Tetratricopeptide repeat
HOCPNFDN_03514 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
HOCPNFDN_03515 0.0 L nucleic acid phosphodiester bond hydrolysis
HOCPNFDN_03516 5.5e-83 S Protein of unknown function, DUF600
HOCPNFDN_03517 6.2e-31 S Colicin immunity protein / pyocin immunity protein
HOCPNFDN_03519 1.8e-212 pstS P T5orf172
HOCPNFDN_03520 0.0 yeeB L DEAD-like helicases superfamily
HOCPNFDN_03521 0.0 yeeA V Type II restriction enzyme, methylase subunits
HOCPNFDN_03522 3.2e-53 L Resolvase, N terminal domain
HOCPNFDN_03523 3.2e-98 L Recombinase
HOCPNFDN_03524 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOCPNFDN_03525 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HOCPNFDN_03526 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HOCPNFDN_03527 4e-156 yerO K Transcriptional regulator
HOCPNFDN_03528 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOCPNFDN_03529 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HOCPNFDN_03530 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOCPNFDN_03531 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOCPNFDN_03532 1.6e-123 sapB S MgtC SapB transporter
HOCPNFDN_03533 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
HOCPNFDN_03534 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HOCPNFDN_03535 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOCPNFDN_03536 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HOCPNFDN_03537 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HOCPNFDN_03539 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HOCPNFDN_03540 4.8e-51 yerC S protein conserved in bacteria
HOCPNFDN_03541 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
HOCPNFDN_03542 0.0 yerA 3.5.4.2 F adenine deaminase
HOCPNFDN_03543 2.7e-27 S Protein of unknown function (DUF2892)
HOCPNFDN_03544 2.3e-232 yjeH E Amino acid permease
HOCPNFDN_03545 3.5e-73 K helix_turn_helix ASNC type
HOCPNFDN_03546 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
HOCPNFDN_03547 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HOCPNFDN_03548 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HOCPNFDN_03549 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HOCPNFDN_03550 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOCPNFDN_03551 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOCPNFDN_03552 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOCPNFDN_03553 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOCPNFDN_03554 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HOCPNFDN_03555 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HOCPNFDN_03556 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HOCPNFDN_03557 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HOCPNFDN_03558 8e-28 yebG S NETI protein
HOCPNFDN_03559 4e-93 yebE S UPF0316 protein
HOCPNFDN_03561 1.1e-118 yebC M Membrane
HOCPNFDN_03562 6e-212 pbuG S permease
HOCPNFDN_03563 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HOCPNFDN_03564 0.0 yebA E COG1305 Transglutaminase-like enzymes
HOCPNFDN_03565 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HOCPNFDN_03566 1.6e-177 yeaC S COG0714 MoxR-like ATPases
HOCPNFDN_03567 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOCPNFDN_03568 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HOCPNFDN_03569 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HOCPNFDN_03570 2.4e-181 yeaA S Protein of unknown function (DUF4003)
HOCPNFDN_03571 9.5e-160 ydjP I Alpha/beta hydrolase family
HOCPNFDN_03572 1.4e-34 ydjO S Cold-inducible protein YdjO
HOCPNFDN_03574 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
HOCPNFDN_03575 4.5e-64 ydjM M Lytic transglycolase
HOCPNFDN_03576 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HOCPNFDN_03577 2.7e-258 iolT EGP Major facilitator Superfamily
HOCPNFDN_03578 4.7e-196 S Ion transport 2 domain protein
HOCPNFDN_03579 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
HOCPNFDN_03580 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HOCPNFDN_03581 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOCPNFDN_03582 5.1e-114 pspA KT Phage shock protein A
HOCPNFDN_03583 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HOCPNFDN_03584 2.7e-255 gutA G MFS/sugar transport protein
HOCPNFDN_03585 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
HOCPNFDN_03586 0.0 K NB-ARC domain
HOCPNFDN_03587 1.1e-08 ydjC S Abhydrolase domain containing 18
HOCPNFDN_03588 4.9e-257 J LlaJI restriction endonuclease
HOCPNFDN_03589 1.2e-199 V AAA domain (dynein-related subfamily)
HOCPNFDN_03591 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HOCPNFDN_03592 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HOCPNFDN_03593 6.4e-66 KL Phage plasmid primase P4 family
HOCPNFDN_03595 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HOCPNFDN_03596 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HOCPNFDN_03597 7.9e-129 ydiL S CAAX protease self-immunity
HOCPNFDN_03598 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HOCPNFDN_03599 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HOCPNFDN_03600 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HOCPNFDN_03601 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HOCPNFDN_03602 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HOCPNFDN_03603 0.0 ydiF S ABC transporter
HOCPNFDN_03604 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOCPNFDN_03605 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HOCPNFDN_03606 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HOCPNFDN_03607 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HOCPNFDN_03608 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HOCPNFDN_03611 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
HOCPNFDN_03612 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
HOCPNFDN_03613 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HOCPNFDN_03614 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
HOCPNFDN_03615 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
HOCPNFDN_03617 0.0 htpG O Molecular chaperone. Has ATPase activity
HOCPNFDN_03618 2.3e-246 csbC EGP Major facilitator Superfamily
HOCPNFDN_03619 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HOCPNFDN_03621 3.7e-176 iolS C Aldo keto reductase
HOCPNFDN_03622 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HOCPNFDN_03623 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HOCPNFDN_03624 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HOCPNFDN_03625 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HOCPNFDN_03626 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HOCPNFDN_03627 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HOCPNFDN_03628 1.3e-235 iolF EGP Major facilitator Superfamily
HOCPNFDN_03629 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HOCPNFDN_03630 2.3e-167 iolH G Xylose isomerase-like TIM barrel
HOCPNFDN_03631 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HOCPNFDN_03632 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HOCPNFDN_03633 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOCPNFDN_03634 1.3e-182 T PhoQ Sensor
HOCPNFDN_03635 9.4e-141 yxdL V ABC transporter, ATP-binding protein
HOCPNFDN_03636 0.0 yxdM V ABC transporter (permease)
HOCPNFDN_03637 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HOCPNFDN_03638 6e-177 fhuD P ABC transporter
HOCPNFDN_03639 8.5e-69
HOCPNFDN_03640 1.9e-16 yxeD
HOCPNFDN_03641 1.3e-20 yxeE
HOCPNFDN_03644 6.2e-151 yidA S hydrolases of the HAD superfamily
HOCPNFDN_03645 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HOCPNFDN_03647 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOCPNFDN_03648 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOCPNFDN_03649 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HOCPNFDN_03650 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
HOCPNFDN_03651 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HOCPNFDN_03652 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
HOCPNFDN_03653 2e-255 yxeQ S MmgE/PrpD family
HOCPNFDN_03654 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
HOCPNFDN_03655 3e-153 yxxB S Domain of Unknown Function (DUF1206)
HOCPNFDN_03656 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HOCPNFDN_03657 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HOCPNFDN_03658 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HOCPNFDN_03659 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HOCPNFDN_03660 6.1e-252 lysP E amino acid
HOCPNFDN_03661 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HOCPNFDN_03662 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HOCPNFDN_03663 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HOCPNFDN_03664 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
HOCPNFDN_03665 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HOCPNFDN_03666 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HOCPNFDN_03667 2.1e-21 S Domain of unknown function (DUF5082)
HOCPNFDN_03668 3.6e-39 yxiC S Family of unknown function (DUF5344)
HOCPNFDN_03669 0.0 S nuclease activity
HOCPNFDN_03670 2.2e-78 S SMI1 / KNR4 family
HOCPNFDN_03671 3.6e-51
HOCPNFDN_03672 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOCPNFDN_03673 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HOCPNFDN_03674 1.1e-72 yxiE T Belongs to the universal stress protein A family
HOCPNFDN_03675 2.9e-168 yxxF EG EamA-like transporter family
HOCPNFDN_03676 0.0 wapA M COG3209 Rhs family protein
HOCPNFDN_03677 1.5e-71 yxxG
HOCPNFDN_03678 1.7e-84
HOCPNFDN_03679 6.4e-63
HOCPNFDN_03680 3.7e-75 yxiG
HOCPNFDN_03681 4.9e-46
HOCPNFDN_03682 3.8e-81
HOCPNFDN_03683 1.2e-96 yxiI S Protein of unknown function (DUF2716)
HOCPNFDN_03684 1.6e-48 yxiJ S YxiJ-like protein
HOCPNFDN_03687 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HOCPNFDN_03688 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HOCPNFDN_03689 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
HOCPNFDN_03690 6.6e-114
HOCPNFDN_03691 8.3e-151 licT K transcriptional antiterminator
HOCPNFDN_03692 5e-144 exoK GH16 M licheninase activity
HOCPNFDN_03693 6.6e-224 citH C Citrate transporter
HOCPNFDN_03694 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HOCPNFDN_03695 2.7e-48 yxiS
HOCPNFDN_03696 1.2e-22 T Domain of unknown function (DUF4163)
HOCPNFDN_03697 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HOCPNFDN_03698 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
HOCPNFDN_03699 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HOCPNFDN_03700 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HOCPNFDN_03701 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HOCPNFDN_03702 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HOCPNFDN_03703 1e-220 yxjG 2.1.1.14 E Methionine synthase
HOCPNFDN_03704 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
HOCPNFDN_03705 1e-87 yxjI S LURP-one-related
HOCPNFDN_03708 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HOCPNFDN_03709 8.9e-116 K helix_turn_helix, Lux Regulon
HOCPNFDN_03710 1.5e-193 yxjM T Signal transduction histidine kinase
HOCPNFDN_03711 2.4e-78 S Protein of unknown function (DUF1453)
HOCPNFDN_03712 1.9e-166 yxjO K LysR substrate binding domain
HOCPNFDN_03713 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
HOCPNFDN_03714 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HOCPNFDN_03715 4.1e-73 yxkC S Domain of unknown function (DUF4352)
HOCPNFDN_03716 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOCPNFDN_03717 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HOCPNFDN_03718 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
HOCPNFDN_03719 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HOCPNFDN_03720 3e-156 yxkH G Polysaccharide deacetylase
HOCPNFDN_03722 0.0 3.4.24.84 O Peptidase family M48
HOCPNFDN_03723 1.5e-229 cimH C COG3493 Na citrate symporter
HOCPNFDN_03724 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
HOCPNFDN_03725 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HOCPNFDN_03726 0.0 cydD V ATP-binding
HOCPNFDN_03727 0.0 cydD V ATP-binding protein
HOCPNFDN_03728 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOCPNFDN_03729 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HOCPNFDN_03730 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HOCPNFDN_03731 3.9e-48 yxlC S Family of unknown function (DUF5345)
HOCPNFDN_03732 1.2e-31
HOCPNFDN_03733 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HOCPNFDN_03734 5.1e-167 yxlF V ABC transporter, ATP-binding protein
HOCPNFDN_03735 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HOCPNFDN_03736 2.1e-216 yxlH EGP Major facilitator Superfamily
HOCPNFDN_03737 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HOCPNFDN_03738 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HOCPNFDN_03739 1.1e-19 yxzF
HOCPNFDN_03740 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HOCPNFDN_03741 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HOCPNFDN_03742 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOCPNFDN_03743 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HOCPNFDN_03744 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HOCPNFDN_03745 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HOCPNFDN_03746 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_03747 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HOCPNFDN_03748 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCPNFDN_03749 1.2e-232 dltB M membrane protein involved in D-alanine export
HOCPNFDN_03750 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCPNFDN_03751 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HOCPNFDN_03752 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HOCPNFDN_03753 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HOCPNFDN_03754 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOCPNFDN_03755 8.1e-88 ywaE K Transcriptional regulator
HOCPNFDN_03756 1.7e-128 ywaF S Integral membrane protein
HOCPNFDN_03757 7e-169 gspA M General stress
HOCPNFDN_03758 4e-153 sacY K transcriptional antiterminator
HOCPNFDN_03759 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOCPNFDN_03760 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
HOCPNFDN_03761 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOCPNFDN_03762 1.8e-127 ywbB S Protein of unknown function (DUF2711)
HOCPNFDN_03763 4.4e-67 ywbC 4.4.1.5 E glyoxalase
HOCPNFDN_03764 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
HOCPNFDN_03765 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
HOCPNFDN_03766 1.9e-209 ywbF EGP Major facilitator Superfamily
HOCPNFDN_03767 2.3e-111 ywbG M effector of murein hydrolase
HOCPNFDN_03768 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HOCPNFDN_03769 4.3e-153 ywbI K Transcriptional regulator
HOCPNFDN_03770 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HOCPNFDN_03771 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HOCPNFDN_03772 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
HOCPNFDN_03773 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
HOCPNFDN_03774 2.6e-225 ywbN P Dyp-type peroxidase family protein
HOCPNFDN_03775 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HOCPNFDN_03776 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOCPNFDN_03777 9.8e-49 ywcB S Protein of unknown function, DUF485
HOCPNFDN_03779 2.2e-122 ywcC K transcriptional regulator
HOCPNFDN_03780 9.5e-60 gtcA S GtrA-like protein
HOCPNFDN_03781 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HOCPNFDN_03782 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HOCPNFDN_03783 1e-35 ywzA S membrane
HOCPNFDN_03784 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HOCPNFDN_03785 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HOCPNFDN_03786 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HOCPNFDN_03787 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HOCPNFDN_03788 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HOCPNFDN_03789 2.9e-202 rodA D Belongs to the SEDS family
HOCPNFDN_03790 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HOCPNFDN_03791 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOCPNFDN_03792 0.0 vpr O Belongs to the peptidase S8 family
HOCPNFDN_03794 2.4e-150 sacT K transcriptional antiterminator
HOCPNFDN_03795 1e-139 focA P Formate/nitrite transporter
HOCPNFDN_03796 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOCPNFDN_03797 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HOCPNFDN_03798 2e-28 ywdA
HOCPNFDN_03799 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HOCPNFDN_03800 1.3e-57 pex K Transcriptional regulator PadR-like family
HOCPNFDN_03801 1.4e-113 ywdD
HOCPNFDN_03803 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HOCPNFDN_03804 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HOCPNFDN_03805 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HOCPNFDN_03806 7.7e-49 ywdI S Family of unknown function (DUF5327)
HOCPNFDN_03807 1.3e-238 ywdJ F Xanthine uracil
HOCPNFDN_03808 4.3e-59 ywdK S small membrane protein
HOCPNFDN_03809 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HOCPNFDN_03810 2.8e-145 spsA M Spore Coat
HOCPNFDN_03811 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
HOCPNFDN_03812 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
HOCPNFDN_03813 4e-164 spsD 2.3.1.210 K Spore Coat
HOCPNFDN_03814 3.2e-214 spsE 2.5.1.56 M acid synthase
HOCPNFDN_03815 9.7e-132 spsF M Spore Coat
HOCPNFDN_03816 1.7e-190 spsG M Spore Coat
HOCPNFDN_03817 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HOCPNFDN_03818 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOCPNFDN_03819 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HOCPNFDN_03820 3.5e-87 spsL 5.1.3.13 M Spore Coat
HOCPNFDN_03821 1.8e-78
HOCPNFDN_03822 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HOCPNFDN_03823 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HOCPNFDN_03824 0.0 rocB E arginine degradation protein
HOCPNFDN_03825 4e-262 lysP E amino acid
HOCPNFDN_03826 4.6e-206 ywfA EGP Major facilitator Superfamily
HOCPNFDN_03827 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HOCPNFDN_03828 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HOCPNFDN_03829 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOCPNFDN_03830 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HOCPNFDN_03831 2.9e-210 bacE EGP Major facilitator Superfamily
HOCPNFDN_03832 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HOCPNFDN_03833 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
HOCPNFDN_03834 1.1e-146 ywfI C May function as heme-dependent peroxidase
HOCPNFDN_03835 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HOCPNFDN_03836 9.2e-164 cysL K Transcriptional regulator
HOCPNFDN_03837 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HOCPNFDN_03838 5.2e-159 ywfM EG EamA-like transporter family
HOCPNFDN_03839 1.6e-111 rsfA_1
HOCPNFDN_03840 3.1e-36 ywzC S Belongs to the UPF0741 family
HOCPNFDN_03841 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HOCPNFDN_03842 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HOCPNFDN_03843 2.8e-79 yffB K Transcriptional regulator
HOCPNFDN_03844 2.6e-242 mmr U Major Facilitator Superfamily
HOCPNFDN_03850 1.9e-45 yrkC G Cupin domain
HOCPNFDN_03851 7.8e-39 yrkD S protein conserved in bacteria
HOCPNFDN_03852 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
HOCPNFDN_03853 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
HOCPNFDN_03854 2.3e-212 yrkH P Rhodanese Homology Domain
HOCPNFDN_03855 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HOCPNFDN_03856 4.3e-117 yrkJ S membrane transporter protein
HOCPNFDN_03857 2.8e-79 S Protein of unknown function with HXXEE motif
HOCPNFDN_03858 1.5e-97 ywrO S Flavodoxin-like fold
HOCPNFDN_03859 6e-105 yrkN K Acetyltransferase (GNAT) family
HOCPNFDN_03860 8.2e-224 yrkO P Protein of unknown function (DUF418)
HOCPNFDN_03861 1.1e-127 T Transcriptional regulator
HOCPNFDN_03862 9e-237 yrkQ T Histidine kinase
HOCPNFDN_03863 2e-68 psiE S Protein PsiE homolog
HOCPNFDN_03864 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOCPNFDN_03865 1.4e-100 yqaB E IrrE N-terminal-like domain
HOCPNFDN_03866 1e-101 adk 2.7.4.3 F adenylate kinase activity
HOCPNFDN_03868 1.1e-56 K sequence-specific DNA binding
HOCPNFDN_03869 6.5e-37 K Helix-turn-helix XRE-family like proteins
HOCPNFDN_03871 1.2e-103
HOCPNFDN_03875 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
HOCPNFDN_03876 2.5e-155 recT L RecT family
HOCPNFDN_03877 4.7e-123 3.1.3.16 L DnaD domain protein
HOCPNFDN_03878 5.9e-168 xkdC L IstB-like ATP binding protein
HOCPNFDN_03880 7.2e-74 rusA L Endodeoxyribonuclease RusA
HOCPNFDN_03881 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
HOCPNFDN_03882 1.6e-166
HOCPNFDN_03883 6.5e-81 L Transposase
HOCPNFDN_03885 6.3e-107 yqaS L DNA packaging
HOCPNFDN_03886 2.4e-253 S phage terminase, large subunit
HOCPNFDN_03887 5.9e-296 yqbA S portal protein
HOCPNFDN_03888 5.7e-169 S Phage Mu protein F like protein
HOCPNFDN_03889 2e-115
HOCPNFDN_03890 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HOCPNFDN_03891 1.9e-167 xkdG S Phage capsid family
HOCPNFDN_03892 3.6e-51 S YqbF, hypothetical protein domain
HOCPNFDN_03893 2.1e-67 S Protein of unknown function (DUF3199)
HOCPNFDN_03894 6.7e-65 yqbH S Domain of unknown function (DUF3599)
HOCPNFDN_03895 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
HOCPNFDN_03896 1.4e-77
HOCPNFDN_03897 3.2e-26
HOCPNFDN_03898 5.5e-256 xkdK S Phage tail sheath C-terminal domain
HOCPNFDN_03899 3.6e-76 xkdM S Phage tail tube protein
HOCPNFDN_03901 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
HOCPNFDN_03902 0.0 xkdO L Transglycosylase SLT domain
HOCPNFDN_03903 9e-114 xkdP S Lysin motif
HOCPNFDN_03904 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
HOCPNFDN_03905 1.8e-38 xkdR S Protein of unknown function (DUF2577)
HOCPNFDN_03906 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HOCPNFDN_03907 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HOCPNFDN_03908 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HOCPNFDN_03909 9.6e-40
HOCPNFDN_03910 2e-221
HOCPNFDN_03911 4.1e-56 xkdW S XkdW protein
HOCPNFDN_03912 1.3e-23
HOCPNFDN_03913 4.8e-165 xepA
HOCPNFDN_03914 2.6e-68 S Bacteriophage holin family
HOCPNFDN_03915 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HOCPNFDN_03917 5e-60
HOCPNFDN_03919 1.1e-104 S Suppressor of fused protein (SUFU)
HOCPNFDN_03920 3.8e-277 A Pre-toxin TG
HOCPNFDN_03923 1.6e-96 S Tetratricopeptide repeat
HOCPNFDN_03924 1.1e-152 yqcI S YqcI/YcgG family
HOCPNFDN_03925 1.6e-54 arsR K ArsR family transcriptional regulator
HOCPNFDN_03926 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOCPNFDN_03927 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
HOCPNFDN_03928 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HOCPNFDN_03929 1.4e-281 cisA2 L Recombinase
HOCPNFDN_03930 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOCPNFDN_03931 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HOCPNFDN_03932 2.3e-133 yqeB
HOCPNFDN_03933 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HOCPNFDN_03934 4.7e-106 yqeD S SNARE associated Golgi protein
HOCPNFDN_03935 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HOCPNFDN_03936 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HOCPNFDN_03938 5.3e-95 yqeG S hydrolase of the HAD superfamily
HOCPNFDN_03939 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HOCPNFDN_03940 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HOCPNFDN_03941 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HOCPNFDN_03942 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOCPNFDN_03943 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HOCPNFDN_03944 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HOCPNFDN_03945 2.9e-139 yqeM Q Methyltransferase
HOCPNFDN_03946 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOCPNFDN_03947 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HOCPNFDN_03948 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HOCPNFDN_03949 0.0 comEC S Competence protein ComEC
HOCPNFDN_03950 4.1e-15 S YqzM-like protein
HOCPNFDN_03951 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HOCPNFDN_03952 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HOCPNFDN_03953 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HOCPNFDN_03954 6.9e-223 spoIIP M stage II sporulation protein P
HOCPNFDN_03955 1e-54 yqxA S Protein of unknown function (DUF3679)
HOCPNFDN_03956 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HOCPNFDN_03957 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
HOCPNFDN_03958 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HOCPNFDN_03959 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOCPNFDN_03960 0.0 dnaK O Heat shock 70 kDa protein
HOCPNFDN_03961 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HOCPNFDN_03962 5.4e-175 prmA J Methylates ribosomal protein L11
HOCPNFDN_03963 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HOCPNFDN_03964 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HOCPNFDN_03965 1.6e-158 yqeW P COG1283 Na phosphate symporter
HOCPNFDN_03966 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HOCPNFDN_03967 2.5e-61 yqeY S Yqey-like protein
HOCPNFDN_03968 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HOCPNFDN_03969 4.3e-122 yqfA S UPF0365 protein
HOCPNFDN_03970 6e-25 yqfB
HOCPNFDN_03971 2.7e-45 yqfC S sporulation protein YqfC
HOCPNFDN_03972 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HOCPNFDN_03973 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
HOCPNFDN_03975 0.0 yqfF S membrane-associated HD superfamily hydrolase
HOCPNFDN_03976 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOCPNFDN_03977 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HOCPNFDN_03978 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HOCPNFDN_03979 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOCPNFDN_03980 8.4e-19 S YqzL-like protein
HOCPNFDN_03981 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
HOCPNFDN_03982 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HOCPNFDN_03983 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HOCPNFDN_03984 4.5e-112 ccpN K CBS domain
HOCPNFDN_03985 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HOCPNFDN_03986 4.5e-88 yaiI S Belongs to the UPF0178 family
HOCPNFDN_03987 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HOCPNFDN_03988 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HOCPNFDN_03989 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HOCPNFDN_03990 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
HOCPNFDN_03991 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HOCPNFDN_03992 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HOCPNFDN_03993 2.9e-14 yqfQ S YqfQ-like protein
HOCPNFDN_03994 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HOCPNFDN_03995 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HOCPNFDN_03996 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HOCPNFDN_03997 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HOCPNFDN_03998 1.9e-77 zur P Belongs to the Fur family
HOCPNFDN_03999 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HOCPNFDN_04000 4.3e-62 yqfX S membrane
HOCPNFDN_04001 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HOCPNFDN_04002 5.2e-47 yqfZ M LysM domain
HOCPNFDN_04003 2.2e-75 yqgA
HOCPNFDN_04004 8.5e-134 yqgB S Protein of unknown function (DUF1189)
HOCPNFDN_04005 4e-73 yqgC S protein conserved in bacteria
HOCPNFDN_04006 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HOCPNFDN_04007 2.5e-231 yqgE EGP Major facilitator superfamily
HOCPNFDN_04008 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HOCPNFDN_04009 5.3e-151 pstS P Phosphate
HOCPNFDN_04010 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
HOCPNFDN_04011 4.4e-158 pstA P Phosphate transport system permease
HOCPNFDN_04012 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOCPNFDN_04013 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOCPNFDN_04014 1.9e-75 yqzC S YceG-like family
HOCPNFDN_04015 9.2e-51 yqzD
HOCPNFDN_04017 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HOCPNFDN_04018 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HOCPNFDN_04019 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HOCPNFDN_04020 2.5e-09 yqgO
HOCPNFDN_04021 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HOCPNFDN_04022 3.1e-33 yqgQ S Protein conserved in bacteria
HOCPNFDN_04023 5.2e-181 glcK 2.7.1.2 G Glucokinase
HOCPNFDN_04024 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HOCPNFDN_04025 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HOCPNFDN_04026 2.7e-199 yqgU
HOCPNFDN_04027 6.9e-50 yqgV S Thiamine-binding protein
HOCPNFDN_04028 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HOCPNFDN_04029 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HOCPNFDN_04030 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HOCPNFDN_04031 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HOCPNFDN_04033 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HOCPNFDN_04034 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HOCPNFDN_04035 7.2e-175 corA P Mg2 transporter protein
HOCPNFDN_04037 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HOCPNFDN_04038 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
HOCPNFDN_04039 1.4e-47 comGC U Required for transformation and DNA binding
HOCPNFDN_04040 4.4e-71 gspH NU protein transport across the cell outer membrane
HOCPNFDN_04041 1.1e-59 comGE
HOCPNFDN_04042 5.5e-49 comGF U Putative Competence protein ComGF
HOCPNFDN_04043 3.7e-42 S ComG operon protein 7
HOCPNFDN_04044 1.4e-26 yqzE S YqzE-like protein
HOCPNFDN_04045 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HOCPNFDN_04046 2.1e-116 yqxM
HOCPNFDN_04047 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HOCPNFDN_04048 2.3e-142 tasA S Cell division protein FtsN
HOCPNFDN_04049 1e-54 sinR K transcriptional
HOCPNFDN_04050 1.2e-24 sinI S Anti-repressor SinI
HOCPNFDN_04051 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HOCPNFDN_04052 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HOCPNFDN_04053 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HOCPNFDN_04054 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HOCPNFDN_04055 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HOCPNFDN_04056 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HOCPNFDN_04057 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HOCPNFDN_04058 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HOCPNFDN_04059 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
HOCPNFDN_04060 2.2e-61 yqhP
HOCPNFDN_04061 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
HOCPNFDN_04062 2.3e-93 yqhR S Conserved membrane protein YqhR
HOCPNFDN_04063 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HOCPNFDN_04064 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HOCPNFDN_04065 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOCPNFDN_04066 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HOCPNFDN_04067 1.2e-171 spoIIIAA S stage III sporulation protein AA
HOCPNFDN_04068 2.9e-85 spoIIIAB S Stage III sporulation protein
HOCPNFDN_04069 7.6e-29 spoIIIAC S stage III sporulation protein AC
HOCPNFDN_04070 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HOCPNFDN_04071 1.3e-197 spoIIIAE S stage III sporulation protein AE
HOCPNFDN_04072 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HOCPNFDN_04073 6.9e-103 spoIIIAG S stage III sporulation protein AG
HOCPNFDN_04074 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HOCPNFDN_04075 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HOCPNFDN_04078 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HOCPNFDN_04079 3.4e-94 M1-753 M FR47-like protein
HOCPNFDN_04080 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HOCPNFDN_04081 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HOCPNFDN_04082 3.9e-84 yuaE S DinB superfamily
HOCPNFDN_04083 7.9e-108 yuaD
HOCPNFDN_04084 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HOCPNFDN_04085 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HOCPNFDN_04086 1.1e-95 yuaC K Belongs to the GbsR family
HOCPNFDN_04087 2.2e-91 yuaB
HOCPNFDN_04088 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
HOCPNFDN_04089 5.4e-237 ktrB P Potassium
HOCPNFDN_04090 1e-38 yiaA S yiaA/B two helix domain
HOCPNFDN_04091 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HOCPNFDN_04092 6.2e-277 yubD P Major Facilitator Superfamily
HOCPNFDN_04093 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HOCPNFDN_04095 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HOCPNFDN_04096 6.3e-197 yubA S transporter activity
HOCPNFDN_04097 3.3e-183 ygjR S Oxidoreductase
HOCPNFDN_04098 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HOCPNFDN_04099 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HOCPNFDN_04100 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HOCPNFDN_04101 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HOCPNFDN_04102 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HOCPNFDN_04103 5.1e-239 mcpA NT chemotaxis protein
HOCPNFDN_04104 2.2e-295 mcpA NT chemotaxis protein
HOCPNFDN_04105 1.5e-222 mcpA NT chemotaxis protein
HOCPNFDN_04106 3.2e-225 mcpA NT chemotaxis protein
HOCPNFDN_04107 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HOCPNFDN_04108 1e-35
HOCPNFDN_04109 2.1e-72 yugU S Uncharacterised protein family UPF0047
HOCPNFDN_04110 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HOCPNFDN_04111 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HOCPNFDN_04112 1.4e-116 yugP S Zn-dependent protease
HOCPNFDN_04113 4.6e-39
HOCPNFDN_04114 1.1e-53 mstX S Membrane-integrating protein Mistic
HOCPNFDN_04115 1.7e-182 yugO P COG1226 Kef-type K transport systems
HOCPNFDN_04116 1.3e-72 yugN S YugN-like family
HOCPNFDN_04118 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HOCPNFDN_04119 2.8e-229 yugK C Dehydrogenase
HOCPNFDN_04120 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HOCPNFDN_04121 1.1e-34 yuzA S Domain of unknown function (DUF378)
HOCPNFDN_04122 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HOCPNFDN_04123 4.3e-200 yugH 2.6.1.1 E Aminotransferase
HOCPNFDN_04124 1.6e-85 alaR K Transcriptional regulator
HOCPNFDN_04125 1e-156 yugF I Hydrolase
HOCPNFDN_04126 9.8e-42 yugE S Domain of unknown function (DUF1871)
HOCPNFDN_04127 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HOCPNFDN_04128 4.6e-233 T PhoQ Sensor
HOCPNFDN_04129 2e-70 kapB G Kinase associated protein B
HOCPNFDN_04130 1.9e-115 kapD L the KinA pathway to sporulation
HOCPNFDN_04132 3.5e-186 yuxJ EGP Major facilitator Superfamily
HOCPNFDN_04133 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HOCPNFDN_04134 6.3e-75 yuxK S protein conserved in bacteria
HOCPNFDN_04135 6.3e-78 yufK S Family of unknown function (DUF5366)
HOCPNFDN_04136 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HOCPNFDN_04137 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HOCPNFDN_04138 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HOCPNFDN_04139 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HOCPNFDN_04140 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
HOCPNFDN_04141 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HOCPNFDN_04142 1.3e-233 maeN C COG3493 Na citrate symporter
HOCPNFDN_04143 1.9e-14
HOCPNFDN_04144 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HOCPNFDN_04145 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HOCPNFDN_04146 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HOCPNFDN_04147 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HOCPNFDN_04148 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HOCPNFDN_04149 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HOCPNFDN_04150 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HOCPNFDN_04151 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
HOCPNFDN_04152 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOCPNFDN_04153 8.2e-221 comP 2.7.13.3 T Histidine kinase
HOCPNFDN_04154 1.9e-193 comP 2.7.13.3 T Histidine kinase
HOCPNFDN_04156 2.5e-162 comQ H Polyprenyl synthetase
HOCPNFDN_04158 1.1e-22 yuzC
HOCPNFDN_04159 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HOCPNFDN_04160 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOCPNFDN_04161 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
HOCPNFDN_04162 1.6e-67 yueI S Protein of unknown function (DUF1694)
HOCPNFDN_04163 7.4e-39 yueH S YueH-like protein
HOCPNFDN_04164 2.1e-32 yueG S Spore germination protein gerPA/gerPF
HOCPNFDN_04165 1.9e-190 yueF S transporter activity
HOCPNFDN_04166 6.1e-72 S Protein of unknown function (DUF2283)
HOCPNFDN_04167 2.9e-24 S Protein of unknown function (DUF2642)
HOCPNFDN_04168 4.8e-96 yueE S phosphohydrolase
HOCPNFDN_04169 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOCPNFDN_04170 6.6e-65 yueC S Family of unknown function (DUF5383)
HOCPNFDN_04171 0.0 esaA S type VII secretion protein EsaA
HOCPNFDN_04172 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HOCPNFDN_04173 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HOCPNFDN_04174 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HOCPNFDN_04175 2.8e-45 esxA S Belongs to the WXG100 family
HOCPNFDN_04176 6.5e-229 yukF QT Transcriptional regulator
HOCPNFDN_04177 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HOCPNFDN_04178 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HOCPNFDN_04179 3.8e-36 mbtH S MbtH-like protein
HOCPNFDN_04180 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOCPNFDN_04181 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HOCPNFDN_04182 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HOCPNFDN_04183 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
HOCPNFDN_04184 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOCPNFDN_04185 1.3e-167 besA S Putative esterase
HOCPNFDN_04186 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HOCPNFDN_04187 1.1e-93 bioY S Biotin biosynthesis protein
HOCPNFDN_04188 3.9e-211 yuiF S antiporter
HOCPNFDN_04189 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HOCPNFDN_04190 1.2e-77 yuiD S protein conserved in bacteria
HOCPNFDN_04191 5.6e-118 yuiC S protein conserved in bacteria
HOCPNFDN_04192 8.4e-27 yuiB S Putative membrane protein
HOCPNFDN_04193 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HOCPNFDN_04194 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HOCPNFDN_04196 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HOCPNFDN_04197 9e-118 paiB K Putative FMN-binding domain
HOCPNFDN_04198 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOCPNFDN_04199 3.7e-63 erpA S Belongs to the HesB IscA family
HOCPNFDN_04200 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HOCPNFDN_04201 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HOCPNFDN_04202 3.2e-39 yuzB S Belongs to the UPF0349 family
HOCPNFDN_04203 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HOCPNFDN_04204 3.5e-57 yuzD S protein conserved in bacteria
HOCPNFDN_04205 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HOCPNFDN_04206 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HOCPNFDN_04207 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HOCPNFDN_04208 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HOCPNFDN_04209 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
HOCPNFDN_04210 2e-199 yutH S Spore coat protein
HOCPNFDN_04211 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HOCPNFDN_04212 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HOCPNFDN_04213 1e-75 yutE S Protein of unknown function DUF86
HOCPNFDN_04214 9.7e-48 yutD S protein conserved in bacteria
HOCPNFDN_04215 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HOCPNFDN_04216 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HOCPNFDN_04217 4.5e-196 lytH M Peptidase, M23
HOCPNFDN_04218 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
HOCPNFDN_04219 4.8e-48 yunC S Domain of unknown function (DUF1805)
HOCPNFDN_04220 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HOCPNFDN_04221 2e-141 yunE S membrane transporter protein
HOCPNFDN_04222 4.3e-171 yunF S Protein of unknown function DUF72
HOCPNFDN_04223 3e-62 yunG
HOCPNFDN_04224 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HOCPNFDN_04225 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
HOCPNFDN_04226 2.1e-236 pbuX F Permease family
HOCPNFDN_04227 1.3e-224 pbuX F xanthine
HOCPNFDN_04228 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HOCPNFDN_04229 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HOCPNFDN_04230 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HOCPNFDN_04231 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HOCPNFDN_04232 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HOCPNFDN_04233 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HOCPNFDN_04234 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HOCPNFDN_04236 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HOCPNFDN_04237 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HOCPNFDN_04238 2.4e-169 bsn L Ribonuclease
HOCPNFDN_04239 1.2e-205 msmX P Belongs to the ABC transporter superfamily
HOCPNFDN_04240 1.1e-135 yurK K UTRA
HOCPNFDN_04241 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HOCPNFDN_04242 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
HOCPNFDN_04243 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
HOCPNFDN_04244 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HOCPNFDN_04245 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HOCPNFDN_04246 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HOCPNFDN_04247 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HOCPNFDN_04249 1e-41
HOCPNFDN_04250 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)