ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMPJKFDJ_00001 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMPJKFDJ_00002 3.9e-159 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMPJKFDJ_00003 2e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMPJKFDJ_00004 3.8e-106 csn2 S CRISPR-associated protein (Cas_Csn2)
HMPJKFDJ_00005 3.2e-07 N PFAM Uncharacterised protein family UPF0150
HMPJKFDJ_00006 1.8e-151 EG Permeases of the drug metabolite transporter (DMT) superfamily
HMPJKFDJ_00008 9.2e-62 ycaO O OsmC-like protein
HMPJKFDJ_00009 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
HMPJKFDJ_00010 9.8e-10 O ADP-ribosylglycohydrolase
HMPJKFDJ_00011 4.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMPJKFDJ_00013 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMPJKFDJ_00014 1.7e-17 XK27_00735
HMPJKFDJ_00015 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPJKFDJ_00016 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HMPJKFDJ_00017 4.8e-163 S CAAX amino terminal protease family protein
HMPJKFDJ_00019 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMPJKFDJ_00020 1.3e-84 mutT 3.6.1.55 F Nudix family
HMPJKFDJ_00021 9.3e-139 ET ABC transporter
HMPJKFDJ_00022 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
HMPJKFDJ_00023 2.3e-209 arcT 2.6.1.1 E Aminotransferase
HMPJKFDJ_00024 1.9e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
HMPJKFDJ_00025 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMPJKFDJ_00026 9.8e-51 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMPJKFDJ_00027 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMPJKFDJ_00028 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMPJKFDJ_00029 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HMPJKFDJ_00030 4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HMPJKFDJ_00031 3.8e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMPJKFDJ_00032 7.4e-220 amrA S membrane protein involved in the export of O-antigen and teichoic acid
HMPJKFDJ_00033 3.2e-178 M Glycosyltransferase group 2 family protein
HMPJKFDJ_00034 7.8e-126 arnC M group 2 family protein
HMPJKFDJ_00035 4.9e-44 S Uncharacterized conserved protein (DUF2304)
HMPJKFDJ_00036 2e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
HMPJKFDJ_00037 3.1e-217 rgpA GT4 M Domain of unknown function (DUF1972)
HMPJKFDJ_00038 1.3e-168 rgpB GT2 M Glycosyltransferase, group 2 family protein
HMPJKFDJ_00039 1.2e-141 rgpC GM Transport permease protein
HMPJKFDJ_00040 3.1e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMPJKFDJ_00041 5.1e-277 GT4 M transferase activity, transferring glycosyl groups
HMPJKFDJ_00042 0.0 rgpF M Rhamnan synthesis protein F
HMPJKFDJ_00043 7.6e-256 M Psort location CytoplasmicMembrane, score
HMPJKFDJ_00044 4.5e-118 radC E Belongs to the UPF0758 family
HMPJKFDJ_00045 1.1e-127 puuD T peptidase C26
HMPJKFDJ_00046 2.1e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMPJKFDJ_00047 8.2e-60 XK27_04120 S Putative amino acid metabolism
HMPJKFDJ_00048 3.4e-208 iscS 2.8.1.7 E Cysteine desulfurase
HMPJKFDJ_00049 5.1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMPJKFDJ_00050 7.1e-101 yjbK S Adenylate cyclase
HMPJKFDJ_00051 6.7e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HMPJKFDJ_00052 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMPJKFDJ_00053 4.5e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HMPJKFDJ_00054 1.5e-172 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HMPJKFDJ_00055 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HMPJKFDJ_00056 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HMPJKFDJ_00057 2.7e-277 amiC P ABC transporter (Permease
HMPJKFDJ_00058 1.3e-165 amiD P ABC transporter (Permease
HMPJKFDJ_00059 2.1e-202 oppD P Belongs to the ABC transporter superfamily
HMPJKFDJ_00060 1.2e-171 oppF P Belongs to the ABC transporter superfamily
HMPJKFDJ_00061 8.1e-124 V Psort location CytoplasmicMembrane, score
HMPJKFDJ_00062 5.4e-119 skfE V abc transporter atp-binding protein
HMPJKFDJ_00063 5.6e-62 yvoA_1 K Transcriptional
HMPJKFDJ_00064 1.4e-147 supH S overlaps another CDS with the same product name
HMPJKFDJ_00065 4.9e-148 XK27_02985 S overlaps another CDS with the same product name
HMPJKFDJ_00066 6.4e-196 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMPJKFDJ_00067 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HMPJKFDJ_00068 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HMPJKFDJ_00069 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMPJKFDJ_00070 8.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMPJKFDJ_00071 1.6e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMPJKFDJ_00072 4.8e-137 stp 3.1.3.16 T phosphatase
HMPJKFDJ_00073 8.9e-302 prkC 2.7.11.1 KLT serine threonine protein kinase
HMPJKFDJ_00074 9e-104 kcsA P Ion transport protein
HMPJKFDJ_00075 4.2e-116 yvqF S Membrane
HMPJKFDJ_00076 3.9e-171 vraS 2.7.13.3 T Histidine kinase
HMPJKFDJ_00077 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMPJKFDJ_00080 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMPJKFDJ_00081 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMPJKFDJ_00082 4.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HMPJKFDJ_00083 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMPJKFDJ_00084 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMPJKFDJ_00085 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMPJKFDJ_00086 8.3e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMPJKFDJ_00087 2e-179 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
HMPJKFDJ_00088 2.2e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMPJKFDJ_00089 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMPJKFDJ_00090 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
HMPJKFDJ_00091 5.7e-291 S Protein of unknown function (DUF3114)
HMPJKFDJ_00093 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HMPJKFDJ_00094 2.1e-297 V abc transporter atp-binding protein
HMPJKFDJ_00095 0.0 V abc transporter atp-binding protein
HMPJKFDJ_00096 1.4e-188 XK27_10075 S abc transporter atp-binding protein
HMPJKFDJ_00097 0.0 glgE 2.3.1.12, 2.4.99.16, 3.2.1.1, 3.2.1.14 GH13,GH18 M Pilin isopeptide linkage domain protein
HMPJKFDJ_00098 0.0 M Pilin isopeptide linkage domain protein
HMPJKFDJ_00099 0.0 zmpB M signal peptide protein, YSIRK family
HMPJKFDJ_00100 0.0 GM domain, Protein
HMPJKFDJ_00101 4.8e-216 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMPJKFDJ_00102 0.0 sbcC L ATPase involved in DNA repair
HMPJKFDJ_00103 3.5e-30 1.3.5.4 C reductase
HMPJKFDJ_00104 3.4e-155 cat 2.3.1.28 S acetyltransferase'
HMPJKFDJ_00105 0.0 M family 8
HMPJKFDJ_00106 6.4e-146 epsH S acetyltransferase'
HMPJKFDJ_00107 3.6e-232 M Glycosyltransferase, family 8
HMPJKFDJ_00108 4.3e-291 tagE 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HMPJKFDJ_00109 5.2e-194 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HMPJKFDJ_00110 3.3e-186 nss M transferase activity, transferring glycosyl groups
HMPJKFDJ_00111 6e-235 M Glycosyltransferase, family 8
HMPJKFDJ_00112 1.3e-167 cpsJ M Glycosyltransferase group 2 family protein
HMPJKFDJ_00113 0.0 M cog cog1442
HMPJKFDJ_00114 1.1e-242 M family 8
HMPJKFDJ_00115 2.3e-165 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HMPJKFDJ_00116 2.8e-309 asp1 S Accessory Sec system protein Asp1
HMPJKFDJ_00117 1.9e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
HMPJKFDJ_00118 4.5e-45 asp3 S Accessory Sec system protein Asp3
HMPJKFDJ_00119 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMPJKFDJ_00120 1.1e-12 S Accessory secretory protein Sec Asp4
HMPJKFDJ_00121 7e-12 S Accessory secretory protein Sec, Asp5
HMPJKFDJ_00126 3.6e-18 3.2.1.51 GH95 U LPXTG cell wall anchor motif
HMPJKFDJ_00127 5.1e-119 K Helix-turn-helix domain, rpiR family
HMPJKFDJ_00128 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMPJKFDJ_00129 0.0 3.5.1.28 M domain protein
HMPJKFDJ_00130 3.2e-90 maa 2.3.1.79 GK Maltose O-acetyltransferase
HMPJKFDJ_00131 3.3e-68 rmaI K Transcriptional regulator, MarR family
HMPJKFDJ_00132 3.5e-239 EGP Major facilitator Superfamily
HMPJKFDJ_00133 6.2e-129 XK27_00785 S CAAX protease self-immunity
HMPJKFDJ_00135 0.0 S dextransucrase activity
HMPJKFDJ_00136 0.0 S dextransucrase activity
HMPJKFDJ_00137 9e-289 S dextransucrase activity
HMPJKFDJ_00138 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HMPJKFDJ_00139 1.6e-100 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HMPJKFDJ_00140 1.6e-62
HMPJKFDJ_00141 0.0 S dextransucrase activity
HMPJKFDJ_00142 6.6e-239 tcdB S dextransucrase activity
HMPJKFDJ_00143 1.6e-91 M Putative cell wall binding repeat
HMPJKFDJ_00144 2.3e-152 S dextransucrase activity
HMPJKFDJ_00145 0.0 S dextransucrase activity
HMPJKFDJ_00146 0.0 S dextransucrase activity
HMPJKFDJ_00147 0.0 S dextransucrase activity
HMPJKFDJ_00148 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMPJKFDJ_00149 1.9e-246 S dextransucrase activity
HMPJKFDJ_00150 4.2e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HMPJKFDJ_00152 1.8e-256 I radical SAM domain protein
HMPJKFDJ_00153 1.2e-176 EGP Major Facilitator Superfamily
HMPJKFDJ_00154 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMPJKFDJ_00155 1.3e-118 yhfC S Putative membrane peptidase family (DUF2324)
HMPJKFDJ_00156 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
HMPJKFDJ_00157 3.6e-15 S integral membrane protein
HMPJKFDJ_00158 9.8e-194 mccF V LD-carboxypeptidase
HMPJKFDJ_00159 9e-08 S Enterocin A Immunity
HMPJKFDJ_00160 0.0 pepO 3.4.24.71 O Peptidase family M13
HMPJKFDJ_00161 5.4e-34 S Immunity protein 41
HMPJKFDJ_00162 1.2e-122 T Ser Thr phosphatase family protein
HMPJKFDJ_00163 1.2e-225 thrE K Psort location CytoplasmicMembrane, score
HMPJKFDJ_00164 1.1e-178 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
HMPJKFDJ_00165 2.4e-96 dhaL 2.7.1.121 S Dihydroxyacetone kinase
HMPJKFDJ_00166 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
HMPJKFDJ_00167 1.6e-177 XK27_10475 S oxidoreductase
HMPJKFDJ_00168 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
HMPJKFDJ_00170 1.1e-281 XK27_07020 S Belongs to the UPF0371 family
HMPJKFDJ_00171 5.7e-212 vex1 V Efflux ABC transporter, permease protein
HMPJKFDJ_00172 1.9e-107 vex2 V abc transporter atp-binding protein
HMPJKFDJ_00173 8.1e-236 vex3 V Efflux ABC transporter, permease protein
HMPJKFDJ_00174 5.7e-115 K Response regulator receiver domain protein
HMPJKFDJ_00175 3.6e-225 vncS 2.7.13.3 T Histidine kinase
HMPJKFDJ_00176 2.4e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
HMPJKFDJ_00177 1.2e-151 galR K Transcriptional regulator
HMPJKFDJ_00178 5.3e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMPJKFDJ_00179 5.5e-286 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HMPJKFDJ_00180 2.1e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMPJKFDJ_00181 1.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMPJKFDJ_00182 0.0 lacS G transporter
HMPJKFDJ_00183 0.0 lacL 3.2.1.23 G -beta-galactosidase
HMPJKFDJ_00184 2.2e-210 S Tetratricopeptide repeat
HMPJKFDJ_00185 5.4e-158 yvgN C reductase
HMPJKFDJ_00186 1.9e-30 XK27_10490
HMPJKFDJ_00187 1.1e-40 DJ nuclease activity
HMPJKFDJ_00188 1.6e-104 yoaK S Protein of unknown function (DUF1275)
HMPJKFDJ_00189 9.2e-110 drgA C nitroreductase
HMPJKFDJ_00190 1.9e-124 T Xre family transcriptional regulator
HMPJKFDJ_00191 6.9e-148 T PhoQ Sensor
HMPJKFDJ_00192 9.1e-92 S Psort location Cytoplasmic, score
HMPJKFDJ_00193 6.4e-126 S ABC-2 family transporter protein
HMPJKFDJ_00194 1.6e-166 bcrA V abc transporter atp-binding protein
HMPJKFDJ_00195 8.4e-227 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMPJKFDJ_00196 3.7e-154 E Alpha/beta hydrolase of unknown function (DUF915)
HMPJKFDJ_00197 2.5e-77 ywnA K Transcriptional regulator
HMPJKFDJ_00198 2.7e-149 1.13.11.2 S glyoxalase
HMPJKFDJ_00199 1.1e-107 XK27_02070 S nitroreductase
HMPJKFDJ_00200 2.7e-27
HMPJKFDJ_00201 2.5e-27 XK27_07105 K transcriptional
HMPJKFDJ_00202 1.1e-06 S Protein of unknown function (DUF3169)
HMPJKFDJ_00203 2.2e-168 ydhF S Aldo keto reductase
HMPJKFDJ_00204 8.1e-97 K WHG domain
HMPJKFDJ_00205 3.4e-24 V abc transporter atp-binding protein
HMPJKFDJ_00206 3e-81 V abc transporter atp-binding protein
HMPJKFDJ_00207 2.1e-205 P FtsX-like permease family
HMPJKFDJ_00208 1.5e-42 S Sugar efflux transporter for intercellular exchange
HMPJKFDJ_00209 1.5e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HMPJKFDJ_00210 1.8e-176 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
HMPJKFDJ_00211 4.7e-165 ET ABC transporter substrate-binding protein
HMPJKFDJ_00212 1.6e-110 ytmL P ABC transporter (Permease
HMPJKFDJ_00213 3e-114 yxeN P ABC transporter, permease protein
HMPJKFDJ_00214 8.2e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
HMPJKFDJ_00215 0.0 S dextransucrase activity
HMPJKFDJ_00216 5e-217 yfnA E amino acid
HMPJKFDJ_00217 3.3e-137 S Carbohydrate-binding domain-containing protein Cthe_2159
HMPJKFDJ_00218 2.6e-15 csbD S CsbD-like
HMPJKFDJ_00219 6.2e-106 S Protein of unknown function (DUF421)
HMPJKFDJ_00220 1.8e-59 S Protein of unknown function (DUF3290)
HMPJKFDJ_00221 5.1e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMPJKFDJ_00222 2.9e-230 brnQ E Component of the transport system for branched-chain amino acids
HMPJKFDJ_00223 7.9e-182 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMPJKFDJ_00225 4.3e-242 norM V Multidrug efflux pump
HMPJKFDJ_00226 2.8e-59 pdxH S pyridoxamine 5'-phosphate oxidase
HMPJKFDJ_00227 5.3e-74 L Transposase
HMPJKFDJ_00228 2.1e-141 L Transposase and inactivated derivatives
HMPJKFDJ_00229 7.2e-223 pbuX F xanthine permease
HMPJKFDJ_00230 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMPJKFDJ_00231 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMPJKFDJ_00232 9.7e-151 T Histidine kinase
HMPJKFDJ_00233 1.1e-133 macB2 V ABC transporter, ATP-binding protein
HMPJKFDJ_00234 0.0 V ABC transporter (permease)
HMPJKFDJ_00235 6.1e-93 XK27_05000 S metal cluster binding
HMPJKFDJ_00236 2.6e-30 liaI KT membrane
HMPJKFDJ_00237 1.2e-14 liaI KT membrane
HMPJKFDJ_00238 4.8e-157 XK27_09825 V abc transporter atp-binding protein
HMPJKFDJ_00239 4e-133 yvfS V Transporter
HMPJKFDJ_00240 2.3e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
HMPJKFDJ_00241 2.3e-165 yocS S Transporter
HMPJKFDJ_00244 1.1e-158 XK27_09825 V 'abc transporter, ATP-binding protein
HMPJKFDJ_00245 1.7e-131 yvfS V ABC-2 type transporter
HMPJKFDJ_00246 2e-189 desK 2.7.13.3 T Histidine kinase
HMPJKFDJ_00247 3.3e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMPJKFDJ_00248 4e-184 S abc transporter atp-binding protein
HMPJKFDJ_00249 4e-142 S ABC-2 family transporter protein
HMPJKFDJ_00250 8.1e-140 S ABC-2 family transporter protein
HMPJKFDJ_00251 2e-77 K Acetyltransferase (GNAT) domain
HMPJKFDJ_00252 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
HMPJKFDJ_00253 1e-50 ywrO S general stress protein
HMPJKFDJ_00254 2e-150 K sequence-specific DNA binding
HMPJKFDJ_00255 7.8e-97 S ABC-2 family transporter protein
HMPJKFDJ_00256 2.6e-152 V ABC transporter, ATP-binding protein
HMPJKFDJ_00257 2.1e-163 K sequence-specific DNA binding
HMPJKFDJ_00258 5.7e-41 3.4.21.89 S RDD family
HMPJKFDJ_00259 3.8e-78 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HMPJKFDJ_00260 2.1e-151 S Protein of unknown function DUF262
HMPJKFDJ_00261 2e-202 S Protein of unknown function DUF262
HMPJKFDJ_00262 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
HMPJKFDJ_00264 8.6e-287 ahpF O alkyl hydroperoxide reductase
HMPJKFDJ_00265 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
HMPJKFDJ_00266 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
HMPJKFDJ_00267 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMPJKFDJ_00268 1.2e-82 S Putative small multi-drug export protein
HMPJKFDJ_00269 2.4e-75 ctsR K Belongs to the CtsR family
HMPJKFDJ_00270 0.0 clpC O Belongs to the ClpA ClpB family
HMPJKFDJ_00271 3.4e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMPJKFDJ_00272 1.1e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMPJKFDJ_00273 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HMPJKFDJ_00274 1.5e-138 S SseB protein N-terminal domain
HMPJKFDJ_00275 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
HMPJKFDJ_00277 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMPJKFDJ_00278 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMPJKFDJ_00280 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMPJKFDJ_00281 2.7e-91 yacP S RNA-binding protein containing a PIN domain
HMPJKFDJ_00282 4.1e-153 degV S DegV family
HMPJKFDJ_00284 5.1e-22 K Transcriptional
HMPJKFDJ_00285 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMPJKFDJ_00286 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HMPJKFDJ_00287 2.5e-180 L Belongs to the 'phage' integrase family
HMPJKFDJ_00288 7.3e-29 S Helix-turn-helix domain
HMPJKFDJ_00289 2.1e-73 S Psort location Cytoplasmic, score 8.87
HMPJKFDJ_00290 1.7e-36 D FtsK/SpoIIIE family
HMPJKFDJ_00293 1.6e-10 K Helix-turn-helix XRE-family like proteins
HMPJKFDJ_00295 2.6e-18
HMPJKFDJ_00296 1.5e-29 K Helix-turn-helix domain
HMPJKFDJ_00297 6e-85
HMPJKFDJ_00298 8.5e-140 srtB 3.4.22.70 S sortase, SrtB family
HMPJKFDJ_00299 1.1e-233 capA M Bacterial capsule synthesis protein
HMPJKFDJ_00300 2.6e-10
HMPJKFDJ_00303 7.8e-102 ygaC J Belongs to the UPF0374 family
HMPJKFDJ_00304 1.3e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMPJKFDJ_00305 3.8e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMPJKFDJ_00306 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
HMPJKFDJ_00307 1.8e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMPJKFDJ_00308 2.8e-114 S HAD hydrolase, family IA, variant 3
HMPJKFDJ_00309 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HMPJKFDJ_00310 5.2e-72 marR K Transcriptional regulator, MarR family
HMPJKFDJ_00311 1.7e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMPJKFDJ_00312 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMPJKFDJ_00313 2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HMPJKFDJ_00314 6.7e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HMPJKFDJ_00315 1.8e-125 IQ reductase
HMPJKFDJ_00316 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMPJKFDJ_00317 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMPJKFDJ_00318 4.3e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMPJKFDJ_00319 4.1e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HMPJKFDJ_00320 3.3e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMPJKFDJ_00321 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HMPJKFDJ_00322 6.2e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMPJKFDJ_00323 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
HMPJKFDJ_00324 1.7e-126 fruR K transcriptional
HMPJKFDJ_00325 1.4e-164 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMPJKFDJ_00326 0.0 fruA 2.7.1.202 G phosphotransferase system
HMPJKFDJ_00327 1.2e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMPJKFDJ_00328 3e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMPJKFDJ_00330 5.2e-212 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HMPJKFDJ_00331 6.3e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMPJKFDJ_00332 2.3e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HMPJKFDJ_00333 2.8e-254 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HMPJKFDJ_00334 7.1e-95 2.3.1.128 K acetyltransferase
HMPJKFDJ_00335 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMPJKFDJ_00336 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMPJKFDJ_00337 2.9e-133 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMPJKFDJ_00338 5e-63 WQ51_03320 S cog cog4835
HMPJKFDJ_00339 2.9e-151 XK27_08360 S EDD domain protein, DegV family
HMPJKFDJ_00340 1.3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMPJKFDJ_00341 2e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMPJKFDJ_00342 0.0 yfmR S abc transporter atp-binding protein
HMPJKFDJ_00343 1e-26 U response to pH
HMPJKFDJ_00344 8.1e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HMPJKFDJ_00345 2.9e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HMPJKFDJ_00346 4.1e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HMPJKFDJ_00347 4e-282 S Psort location CytoplasmicMembrane, score
HMPJKFDJ_00348 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMPJKFDJ_00349 3.3e-74 K DNA-binding transcription factor activity
HMPJKFDJ_00350 0.0 lmrA1 V abc transporter atp-binding protein
HMPJKFDJ_00351 0.0 lmrA2 V abc transporter atp-binding protein
HMPJKFDJ_00352 3.3e-112 K Acetyltransferase (GNAT) family
HMPJKFDJ_00353 5.1e-113 2.7.6.5 S Region found in RelA / SpoT proteins
HMPJKFDJ_00354 1.7e-117 T response regulator
HMPJKFDJ_00355 8.5e-213 sptS 2.7.13.3 T Histidine kinase
HMPJKFDJ_00356 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMPJKFDJ_00357 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMPJKFDJ_00358 4.5e-160 cvfB S Protein conserved in bacteria
HMPJKFDJ_00359 3.7e-34 yozE S Belongs to the UPF0346 family
HMPJKFDJ_00360 8.3e-136 sip M LysM domain protein
HMPJKFDJ_00361 2.8e-191 phoH T phosphate starvation-inducible protein PhoH
HMPJKFDJ_00366 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMPJKFDJ_00367 9.6e-163 S reductase
HMPJKFDJ_00368 4.7e-168 K transcriptional regulator (lysR family)
HMPJKFDJ_00369 2.7e-105 S CAAX amino terminal protease family protein
HMPJKFDJ_00370 2.5e-307 S Glucan-binding protein C
HMPJKFDJ_00371 7.3e-163 S CHAP domain
HMPJKFDJ_00372 3.7e-54 insK L Integrase core domain protein
HMPJKFDJ_00373 5.2e-78 L transposition
HMPJKFDJ_00374 3.5e-185 coiA 3.6.4.12 S Competence protein
HMPJKFDJ_00375 0.0 pepF E oligoendopeptidase F
HMPJKFDJ_00376 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
HMPJKFDJ_00377 1.9e-127 yrrM 2.1.1.104 S O-Methyltransferase
HMPJKFDJ_00378 7.8e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HMPJKFDJ_00379 3.3e-83 yxjI S LURP-one-related
HMPJKFDJ_00380 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMPJKFDJ_00381 5e-13 L COG1943 Transposase and inactivated derivatives
HMPJKFDJ_00382 2.8e-134 fasA KT Response regulator of the LytR AlgR family
HMPJKFDJ_00383 1e-243 fasC 2.7.13.3 T protein histidine kinase activity
HMPJKFDJ_00384 4.6e-209 hpk9 2.7.13.3 T protein histidine kinase activity
HMPJKFDJ_00385 2e-155 hpk9 2.7.13.3 T protein histidine kinase activity
HMPJKFDJ_00386 6.7e-232 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HMPJKFDJ_00387 3.5e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMPJKFDJ_00388 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HMPJKFDJ_00389 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMPJKFDJ_00390 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMPJKFDJ_00391 1.2e-50 S Protein of unknown function (DUF3397)
HMPJKFDJ_00392 3e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HMPJKFDJ_00393 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
HMPJKFDJ_00394 1.5e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMPJKFDJ_00395 3e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
HMPJKFDJ_00396 1.2e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HMPJKFDJ_00397 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
HMPJKFDJ_00398 7.9e-230 XK27_09615 C reductase
HMPJKFDJ_00399 4e-139 fnt P Formate nitrite transporter
HMPJKFDJ_00400 1.1e-98 XK27_08585 S Psort location CytoplasmicMembrane, score
HMPJKFDJ_00401 9.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMPJKFDJ_00402 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMPJKFDJ_00403 2e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HMPJKFDJ_00404 2.8e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMPJKFDJ_00405 7.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMPJKFDJ_00406 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMPJKFDJ_00407 6.1e-137 S HAD hydrolase, family IA, variant
HMPJKFDJ_00408 7.3e-155 rrmA 2.1.1.187 Q methyltransferase
HMPJKFDJ_00412 3.9e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMPJKFDJ_00413 1.9e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMPJKFDJ_00414 8.3e-37 yeeD O sulfur carrier activity
HMPJKFDJ_00415 2e-186 yeeE S Sulphur transport
HMPJKFDJ_00416 1.1e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMPJKFDJ_00417 3.9e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMPJKFDJ_00418 5.9e-08 S Domain of unknown function (DUF4651)
HMPJKFDJ_00419 1.3e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HMPJKFDJ_00420 3.7e-129 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMPJKFDJ_00421 4.8e-101 S CAAX amino terminal protease family protein
HMPJKFDJ_00423 5.4e-105 V CAAX protease self-immunity
HMPJKFDJ_00424 1.5e-26 lanR K sequence-specific DNA binding
HMPJKFDJ_00425 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMPJKFDJ_00426 7.7e-177 ytxK 2.1.1.72 L DNA methylase
HMPJKFDJ_00427 1.7e-11 comGF U Putative Competence protein ComGF
HMPJKFDJ_00428 5.3e-72 comGF U Competence protein ComGF
HMPJKFDJ_00429 2.4e-15 NU Type II secretory pathway pseudopilin
HMPJKFDJ_00430 6.4e-70 cglD NU Competence protein
HMPJKFDJ_00431 2.2e-43 comGC U Required for transformation and DNA binding
HMPJKFDJ_00432 9.7e-144 cglB U protein transport across the cell outer membrane
HMPJKFDJ_00433 1.6e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HMPJKFDJ_00434 1e-68 S cog cog4699
HMPJKFDJ_00435 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMPJKFDJ_00436 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMPJKFDJ_00437 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMPJKFDJ_00438 6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMPJKFDJ_00439 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMPJKFDJ_00440 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
HMPJKFDJ_00441 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HMPJKFDJ_00442 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HMPJKFDJ_00443 3.8e-304 yloV S kinase related to dihydroxyacetone kinase
HMPJKFDJ_00444 1.4e-57 asp S cog cog1302
HMPJKFDJ_00445 5.4e-226 norN V Mate efflux family protein
HMPJKFDJ_00446 1.6e-277 thrC 4.2.3.1 E Threonine synthase
HMPJKFDJ_00449 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMPJKFDJ_00450 0.0 pepO 3.4.24.71 O Peptidase family M13
HMPJKFDJ_00451 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HMPJKFDJ_00452 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMPJKFDJ_00453 6.7e-125 treR K trehalose operon
HMPJKFDJ_00454 6.3e-94 ywlG S Belongs to the UPF0340 family
HMPJKFDJ_00456 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
HMPJKFDJ_00458 1.1e-240 6.3.2.2 H gamma-glutamylcysteine synthetase
HMPJKFDJ_00459 4.4e-62 rplQ J ribosomal protein l17
HMPJKFDJ_00460 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMPJKFDJ_00461 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMPJKFDJ_00462 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMPJKFDJ_00463 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMPJKFDJ_00464 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMPJKFDJ_00465 6.9e-113 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMPJKFDJ_00466 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMPJKFDJ_00467 1.7e-57 rplO J binds to the 23S rRNA
HMPJKFDJ_00468 1.9e-23 rpmD J ribosomal protein l30
HMPJKFDJ_00469 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMPJKFDJ_00470 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMPJKFDJ_00471 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMPJKFDJ_00472 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMPJKFDJ_00473 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMPJKFDJ_00474 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMPJKFDJ_00475 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMPJKFDJ_00476 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMPJKFDJ_00477 1.7e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMPJKFDJ_00478 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HMPJKFDJ_00479 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMPJKFDJ_00480 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMPJKFDJ_00481 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMPJKFDJ_00482 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMPJKFDJ_00483 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMPJKFDJ_00484 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMPJKFDJ_00485 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
HMPJKFDJ_00486 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMPJKFDJ_00487 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HMPJKFDJ_00488 3.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMPJKFDJ_00489 0.0 XK27_09800 I Acyltransferase
HMPJKFDJ_00490 9.7e-36 XK27_09805 S MORN repeat protein
HMPJKFDJ_00491 9.8e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMPJKFDJ_00492 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMPJKFDJ_00493 2.4e-92 adk 2.7.4.3 F topology modulation protein
HMPJKFDJ_00495 4.7e-197 ltrA S Low temperature requirement protein
HMPJKFDJ_00496 2.5e-173 yeiH S membrane
HMPJKFDJ_00497 8e-88 K sequence-specific DNA binding
HMPJKFDJ_00498 1.5e-156 L Replication initiation factor
HMPJKFDJ_00499 1.4e-18 S Domain of unknown function (DUF3173)
HMPJKFDJ_00500 1.6e-213 int L Belongs to the 'phage' integrase family
HMPJKFDJ_00502 1.3e-232 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HMPJKFDJ_00503 1.9e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMPJKFDJ_00504 6.3e-44 yrzL S Belongs to the UPF0297 family
HMPJKFDJ_00505 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMPJKFDJ_00506 3.2e-44 yrzB S Belongs to the UPF0473 family
HMPJKFDJ_00507 4.7e-291 ccs S the current gene model (or a revised gene model) may contain a frame shift
HMPJKFDJ_00508 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMPJKFDJ_00509 7.5e-14
HMPJKFDJ_00510 5.4e-89 XK27_10930 K acetyltransferase
HMPJKFDJ_00511 2.4e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMPJKFDJ_00512 7.5e-121 yaaA S Belongs to the UPF0246 family
HMPJKFDJ_00513 1.1e-167 XK27_01785 S cog cog1284
HMPJKFDJ_00514 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMPJKFDJ_00516 9.5e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMPJKFDJ_00517 4.1e-75 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMPJKFDJ_00518 2.1e-152 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMPJKFDJ_00519 1.9e-219 metE 2.1.1.14 E Methionine synthase
HMPJKFDJ_00520 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMPJKFDJ_00521 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMPJKFDJ_00522 1e-27 ybaJ Q Methyltransferase domain
HMPJKFDJ_00523 7.2e-31 S Membrane
HMPJKFDJ_00524 3.2e-90
HMPJKFDJ_00525 2.2e-21 S Small integral membrane protein
HMPJKFDJ_00526 3.8e-86 S Asp23 family, cell envelope-related function
HMPJKFDJ_00527 8.3e-12 S CsbD-like
HMPJKFDJ_00528 5.2e-265 L DNA integration
HMPJKFDJ_00530 3.7e-193 L Replication initiation factor
HMPJKFDJ_00531 6.4e-62
HMPJKFDJ_00532 6.2e-15
HMPJKFDJ_00533 9.1e-66
HMPJKFDJ_00536 0.0 clpE O Belongs to the ClpA ClpB family
HMPJKFDJ_00537 1.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMPJKFDJ_00538 1e-34 ykuJ S protein conserved in bacteria
HMPJKFDJ_00539 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HMPJKFDJ_00540 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPJKFDJ_00541 7e-78 feoA P FeoA domain protein
HMPJKFDJ_00542 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HMPJKFDJ_00543 6.6e-08
HMPJKFDJ_00544 6.1e-148 I Alpha/beta hydrolase family
HMPJKFDJ_00545 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMPJKFDJ_00546 1.1e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMPJKFDJ_00547 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HMPJKFDJ_00548 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMPJKFDJ_00549 4.6e-149 licT K antiterminator
HMPJKFDJ_00550 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMPJKFDJ_00551 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HMPJKFDJ_00552 2.2e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMPJKFDJ_00553 1.3e-148 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMPJKFDJ_00554 5.1e-102 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMPJKFDJ_00555 1.1e-220 mdtG EGP Major facilitator Superfamily
HMPJKFDJ_00556 2e-33 secG U Preprotein translocase subunit SecG
HMPJKFDJ_00557 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMPJKFDJ_00558 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMPJKFDJ_00559 5.7e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMPJKFDJ_00560 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HMPJKFDJ_00561 1.2e-194 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HMPJKFDJ_00562 2.4e-181 ccpA K Catabolite control protein A
HMPJKFDJ_00563 2.5e-200 yyaQ S YjbR
HMPJKFDJ_00564 4.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMPJKFDJ_00565 7.9e-79 yueI S Protein of unknown function (DUF1694)
HMPJKFDJ_00566 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMPJKFDJ_00567 2.6e-203 S Phage integrase family
HMPJKFDJ_00568 5.2e-13 S Short C-terminal domain
HMPJKFDJ_00569 9e-25 E Zn peptidase
HMPJKFDJ_00571 4.6e-38
HMPJKFDJ_00572 5.5e-48 S sequence-specific DNA binding
HMPJKFDJ_00573 7.7e-30 S sequence-specific DNA binding
HMPJKFDJ_00577 1e-109
HMPJKFDJ_00578 6.1e-09 S ORF6C domain
HMPJKFDJ_00581 2.7e-80 M Pilin isopeptide linkage domain protein
HMPJKFDJ_00582 4.8e-71 S Siphovirus Gp157
HMPJKFDJ_00583 5.6e-124 S AAA domain
HMPJKFDJ_00584 2.5e-223 S helicase activity
HMPJKFDJ_00585 6.3e-68 S Protein of unknown function (DUF669)
HMPJKFDJ_00586 6.1e-106 S Bifunctional DNA primase/polymerase, N-terminal
HMPJKFDJ_00587 4.6e-200 S DNA primase
HMPJKFDJ_00588 1e-48 S hydrolase activity, acting on ester bonds
HMPJKFDJ_00595 2.8e-12 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HMPJKFDJ_00597 2.3e-18 S YopX protein
HMPJKFDJ_00599 3.3e-31
HMPJKFDJ_00600 1.7e-32 L DNA packaging
HMPJKFDJ_00601 1.7e-232 S Terminase-like family
HMPJKFDJ_00602 6.4e-91 S Phage portal protein, SPP1 Gp6-like
HMPJKFDJ_00603 6.4e-96 S Phage portal protein, SPP1 Gp6-like
HMPJKFDJ_00604 1.3e-134 S Phage Mu protein F like protein
HMPJKFDJ_00606 1.6e-23 S Domain of unknown function (DUF4355)
HMPJKFDJ_00607 1e-15
HMPJKFDJ_00608 9.1e-147 S Phage major capsid protein E
HMPJKFDJ_00610 3.8e-36 S Phage gp6-like head-tail connector protein
HMPJKFDJ_00612 9.5e-37 S exonuclease activity
HMPJKFDJ_00613 2.9e-53
HMPJKFDJ_00614 6.5e-74 S Phage major tail protein 2
HMPJKFDJ_00615 3.3e-40 S Pfam:Phage_TAC_12
HMPJKFDJ_00617 3.1e-170 S peptidoglycan catabolic process
HMPJKFDJ_00618 3.3e-177 S Phage tail protein
HMPJKFDJ_00619 0.0 S peptidoglycan catabolic process
HMPJKFDJ_00620 6.8e-263
HMPJKFDJ_00621 6.4e-12
HMPJKFDJ_00622 7e-61 S Pfam:Phage_holin_4_1
HMPJKFDJ_00623 1.1e-23 S COG5546 Small integral membrane protein
HMPJKFDJ_00624 2.9e-104 M lysozyme activity
HMPJKFDJ_00629 1.2e-25 WQ51_00785
HMPJKFDJ_00630 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMPJKFDJ_00631 2.6e-219 ywbD 2.1.1.191 J Methyltransferase
HMPJKFDJ_00632 1.8e-119 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMPJKFDJ_00633 1.3e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMPJKFDJ_00634 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMPJKFDJ_00635 9.9e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMPJKFDJ_00636 1.8e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HMPJKFDJ_00637 4.2e-53 yheA S Belongs to the UPF0342 family
HMPJKFDJ_00638 2.9e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMPJKFDJ_00639 2.2e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMPJKFDJ_00640 2.9e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMPJKFDJ_00641 3.9e-153 pheA 4.2.1.51 E Prephenate dehydratase
HMPJKFDJ_00642 9.8e-245 msrR K Transcriptional regulator
HMPJKFDJ_00643 1.3e-152 ydiA P C4-dicarboxylate transporter malic acid transport
HMPJKFDJ_00644 1.5e-200 I acyl-CoA dehydrogenase
HMPJKFDJ_00645 2e-97 mip S hydroperoxide reductase activity
HMPJKFDJ_00646 1.4e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMPJKFDJ_00647 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
HMPJKFDJ_00648 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
HMPJKFDJ_00649 1.6e-61 smtB K Transcriptional regulator
HMPJKFDJ_00650 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HMPJKFDJ_00652 5.5e-141 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMPJKFDJ_00653 3.7e-73 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
HMPJKFDJ_00654 4.5e-203 yeaN P transporter
HMPJKFDJ_00655 1.4e-150 yitS S EDD domain protein, DegV family
HMPJKFDJ_00656 6.8e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
HMPJKFDJ_00657 1.2e-95 ypgQ F HD superfamily hydrolase
HMPJKFDJ_00658 7.5e-128 S CAAX amino terminal protease family
HMPJKFDJ_00659 1.2e-112 cutC P Participates in the control of copper homeostasis
HMPJKFDJ_00660 4e-09 M family 8
HMPJKFDJ_00661 0.0 M family 8
HMPJKFDJ_00662 3.3e-60 L thioesterase
HMPJKFDJ_00663 4.2e-53 bta 1.8.1.8 CO cell redox homeostasis
HMPJKFDJ_00664 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMPJKFDJ_00665 3.4e-14 rpmH J Ribosomal protein L34
HMPJKFDJ_00666 5.9e-100 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HMPJKFDJ_00667 2.4e-104 K Transcriptional regulator
HMPJKFDJ_00668 3.5e-175 jag S RNA-binding protein
HMPJKFDJ_00669 6.3e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMPJKFDJ_00670 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMPJKFDJ_00671 3.3e-269 argH 4.3.2.1 E Argininosuccinate lyase
HMPJKFDJ_00672 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMPJKFDJ_00676 2.6e-10
HMPJKFDJ_00681 9.2e-110 mreC M Involved in formation and maintenance of cell shape
HMPJKFDJ_00682 4.2e-84 mreD M rod shape-determining protein MreD
HMPJKFDJ_00683 1.1e-89 usp 3.5.1.28 CBM50 S CHAP domain
HMPJKFDJ_00688 2.6e-10
HMPJKFDJ_00691 1.9e-07
HMPJKFDJ_00696 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMPJKFDJ_00697 2.1e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HMPJKFDJ_00698 5.5e-36 XK27_02060 S Transglycosylase associated protein
HMPJKFDJ_00699 3.9e-72 badR K Transcriptional regulator, marr family
HMPJKFDJ_00700 5.5e-95 S reductase
HMPJKFDJ_00701 1.5e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMPJKFDJ_00702 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMPJKFDJ_00703 6.6e-237 dltB M Membrane protein involved in D-alanine export
HMPJKFDJ_00704 1.3e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMPJKFDJ_00705 0.0 XK27_10035 V abc transporter atp-binding protein
HMPJKFDJ_00706 1.2e-281 yfiB1 V abc transporter atp-binding protein
HMPJKFDJ_00707 1.9e-99 pvaA M lytic transglycosylase activity
HMPJKFDJ_00708 5.5e-178 ndpA S 37-kD nucleoid-associated bacterial protein
HMPJKFDJ_00709 1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMPJKFDJ_00710 1.3e-62 XK27_05710 K Acetyltransferase (GNAT) domain
HMPJKFDJ_00711 1.2e-95 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMPJKFDJ_00712 5.2e-145 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMPJKFDJ_00713 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMPJKFDJ_00714 1.1e-107 tdk 2.7.1.21 F thymidine kinase
HMPJKFDJ_00715 2.1e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HMPJKFDJ_00716 1.5e-154 gst O Glutathione S-transferase
HMPJKFDJ_00717 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HMPJKFDJ_00718 3.4e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMPJKFDJ_00719 4.4e-45 rpmE2 J 50S ribosomal protein L31
HMPJKFDJ_00720 2.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
HMPJKFDJ_00721 5.8e-164 ypuA S secreted protein
HMPJKFDJ_00722 2.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
HMPJKFDJ_00723 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HMPJKFDJ_00724 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMPJKFDJ_00725 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMPJKFDJ_00726 1.4e-256 noxE P NADH oxidase
HMPJKFDJ_00727 1.1e-294 yfmM S abc transporter atp-binding protein
HMPJKFDJ_00728 8.9e-82 XK27_01265 S ECF-type riboflavin transporter, S component
HMPJKFDJ_00729 7.2e-150 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HMPJKFDJ_00730 3.3e-86 S ECF-type riboflavin transporter, S component
HMPJKFDJ_00732 4.5e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMPJKFDJ_00733 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HMPJKFDJ_00735 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMPJKFDJ_00736 6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMPJKFDJ_00737 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMPJKFDJ_00738 2.9e-22 WQ51_00220 K Helix-turn-helix domain
HMPJKFDJ_00739 3.7e-91 S Protein of unknown function (DUF3278)
HMPJKFDJ_00740 0.0 smc D Required for chromosome condensation and partitioning
HMPJKFDJ_00741 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMPJKFDJ_00742 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMPJKFDJ_00743 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMPJKFDJ_00745 2.9e-290 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMPJKFDJ_00746 2.7e-91 pat 2.3.1.183 M acetyltransferase
HMPJKFDJ_00747 1.3e-273 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMPJKFDJ_00748 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMPJKFDJ_00749 1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HMPJKFDJ_00750 8.5e-122 sdaAB 4.3.1.17 E L-serine dehydratase
HMPJKFDJ_00751 2.8e-149 sdaAA 4.3.1.17 E L-serine dehydratase
HMPJKFDJ_00753 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HMPJKFDJ_00754 8e-148 cah 4.2.1.1 P carbonic anhydrase
HMPJKFDJ_00755 5.3e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMPJKFDJ_00757 1.3e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HMPJKFDJ_00758 3.2e-141 cppA E CppA N-terminal
HMPJKFDJ_00759 5.9e-99 V CAAX protease self-immunity
HMPJKFDJ_00760 9.8e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HMPJKFDJ_00761 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMPJKFDJ_00767 4e-10 S Bacteriocin class II with double-glycine leader peptide
HMPJKFDJ_00768 0.0 mdlB V abc transporter atp-binding protein
HMPJKFDJ_00769 0.0 mdlA V abc transporter atp-binding protein
HMPJKFDJ_00772 9.7e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
HMPJKFDJ_00773 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HMPJKFDJ_00774 5.6e-63 yutD J protein conserved in bacteria
HMPJKFDJ_00775 3.1e-259 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMPJKFDJ_00777 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMPJKFDJ_00778 1.7e-182 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMPJKFDJ_00779 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HMPJKFDJ_00780 2.4e-45 ftsL D cell division protein FtsL
HMPJKFDJ_00781 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMPJKFDJ_00784 5e-69 yhaI J Protein of unknown function (DUF805)
HMPJKFDJ_00785 3.1e-63 yhaI S Protein of unknown function (DUF805)
HMPJKFDJ_00786 1.6e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMPJKFDJ_00787 6.3e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMPJKFDJ_00788 5.1e-274 XK27_00765
HMPJKFDJ_00789 3.1e-133 ecsA_2 V abc transporter atp-binding protein
HMPJKFDJ_00790 4.7e-126 S Protein of unknown function (DUF554)
HMPJKFDJ_00791 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMPJKFDJ_00792 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HMPJKFDJ_00793 9.2e-240 2.7.13.3 T protein histidine kinase activity
HMPJKFDJ_00794 2.7e-241 dcuS 2.7.13.3 T protein histidine kinase activity
HMPJKFDJ_00795 8.9e-14
HMPJKFDJ_00798 5.8e-146 V Psort location CytoplasmicMembrane, score
HMPJKFDJ_00800 9.2e-300 O MreB/Mbl protein
HMPJKFDJ_00801 6.3e-112 liaI S membrane
HMPJKFDJ_00802 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
HMPJKFDJ_00803 2.3e-296 KT response to antibiotic
HMPJKFDJ_00804 1.2e-113 yebC M Membrane
HMPJKFDJ_00805 4e-259 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
HMPJKFDJ_00806 2.6e-169 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HMPJKFDJ_00808 2.9e-31 yozG K Transcriptional regulator
HMPJKFDJ_00812 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMPJKFDJ_00813 3.2e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMPJKFDJ_00814 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMPJKFDJ_00815 1.8e-195 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMPJKFDJ_00816 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMPJKFDJ_00817 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMPJKFDJ_00819 1.6e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMPJKFDJ_00820 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HMPJKFDJ_00821 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMPJKFDJ_00822 4.4e-285 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
HMPJKFDJ_00823 6e-177 scrR K purine nucleotide biosynthetic process
HMPJKFDJ_00824 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMPJKFDJ_00825 1.7e-61 yqhY S protein conserved in bacteria
HMPJKFDJ_00826 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMPJKFDJ_00827 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
HMPJKFDJ_00828 2.4e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HMPJKFDJ_00829 1.5e-141 S Macro domain protein
HMPJKFDJ_00830 2.4e-50 trxA O Belongs to the thioredoxin family
HMPJKFDJ_00831 7.2e-74 yccU S CoA-binding protein
HMPJKFDJ_00832 1.4e-142 tatD L Hydrolase, tatd
HMPJKFDJ_00833 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMPJKFDJ_00834 7.6e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMPJKFDJ_00836 4e-164 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMPJKFDJ_00837 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMPJKFDJ_00838 1.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMPJKFDJ_00839 1.4e-170 rmuC S RmuC domain protein
HMPJKFDJ_00840 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
HMPJKFDJ_00841 5.3e-142 purR 2.4.2.7 F operon repressor
HMPJKFDJ_00842 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMPJKFDJ_00843 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMPJKFDJ_00844 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMPJKFDJ_00845 6.2e-185 gap 1.2.1.12 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMPJKFDJ_00846 2.1e-123
HMPJKFDJ_00847 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMPJKFDJ_00848 3e-87 S Fusaric acid resistance protein-like
HMPJKFDJ_00849 2.5e-62 glnR K Transcriptional regulator
HMPJKFDJ_00850 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
HMPJKFDJ_00851 6.6e-116 pscB M CHAP domain protein
HMPJKFDJ_00852 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMPJKFDJ_00853 1.5e-33 ykzG S Belongs to the UPF0356 family
HMPJKFDJ_00854 1.8e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HMPJKFDJ_00855 9e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HMPJKFDJ_00856 4.3e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMPJKFDJ_00857 4.8e-112 azlC E AzlC protein
HMPJKFDJ_00858 3.1e-45 azlD S branched-chain amino acid
HMPJKFDJ_00859 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMPJKFDJ_00860 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMPJKFDJ_00861 4.5e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMPJKFDJ_00862 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMPJKFDJ_00863 3e-93 cvpA S toxin biosynthetic process
HMPJKFDJ_00864 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMPJKFDJ_00865 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMPJKFDJ_00867 6e-38
HMPJKFDJ_00868 7.6e-10
HMPJKFDJ_00870 1.8e-220 mutY L A G-specific adenine glycosylase
HMPJKFDJ_00871 1.1e-42 XK27_05745
HMPJKFDJ_00872 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HMPJKFDJ_00873 1.6e-80 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMPJKFDJ_00874 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMPJKFDJ_00876 2.5e-121 XK27_01040 S Protein of unknown function (DUF1129)
HMPJKFDJ_00877 5.8e-169 corA P COG0598 Mg2 and Co2 transporters
HMPJKFDJ_00878 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HMPJKFDJ_00879 4.9e-190 V PFAM secretion protein HlyD family protein
HMPJKFDJ_00880 4.7e-72 L COG1943 Transposase and inactivated derivatives
HMPJKFDJ_00882 3.4e-30 blpT
HMPJKFDJ_00883 1e-29 rpsT J Binds directly to 16S ribosomal RNA
HMPJKFDJ_00884 1.2e-169 coaA 2.7.1.33 F Pantothenic acid kinase
HMPJKFDJ_00885 1.1e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
HMPJKFDJ_00886 5.6e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HMPJKFDJ_00887 6e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMPJKFDJ_00888 4.8e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HMPJKFDJ_00889 2.5e-192 tcsA S membrane
HMPJKFDJ_00890 2.9e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HMPJKFDJ_00891 3.9e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
HMPJKFDJ_00892 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HMPJKFDJ_00893 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HMPJKFDJ_00894 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMPJKFDJ_00895 6.8e-81 ypmB S Protein conserved in bacteria
HMPJKFDJ_00896 1.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HMPJKFDJ_00897 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HMPJKFDJ_00898 4.1e-18
HMPJKFDJ_00899 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
HMPJKFDJ_00900 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HMPJKFDJ_00901 3.9e-83 queD 4.1.2.50, 4.2.3.12 H synthase
HMPJKFDJ_00902 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HMPJKFDJ_00903 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HMPJKFDJ_00904 3e-197 D nuclear chromosome segregation
HMPJKFDJ_00905 3.7e-137 yejC S cyclic nucleotide-binding protein
HMPJKFDJ_00906 7e-164 rapZ S Displays ATPase and GTPase activities
HMPJKFDJ_00907 5.3e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMPJKFDJ_00908 5.7e-161 whiA K May be required for sporulation
HMPJKFDJ_00909 1.5e-274 pepD E Dipeptidase
HMPJKFDJ_00910 4.6e-146 XK27_10720 D peptidase activity
HMPJKFDJ_00911 1.2e-291 adcA P Belongs to the bacterial solute-binding protein 9 family
HMPJKFDJ_00912 2.6e-09
HMPJKFDJ_00914 7.4e-170 yeiH S Membrane
HMPJKFDJ_00915 1.3e-128 mur1 3.4.17.14, 3.5.1.28 NU muramidase
HMPJKFDJ_00916 1.5e-284 sulP P Sulfate permease and related transporters (MFS superfamily)
HMPJKFDJ_00917 1.2e-103
HMPJKFDJ_00918 1.4e-118 estA E GDSL-like Lipase/Acylhydrolase
HMPJKFDJ_00919 8.1e-95 S CAAX protease self-immunity
HMPJKFDJ_00920 5e-52
HMPJKFDJ_00922 1.7e-63 yqeB S Pyrimidine dimer DNA glycosylase
HMPJKFDJ_00923 1.2e-59 S Protein of unknown function (DUF1722)
HMPJKFDJ_00924 1.7e-19 S Bacterial lipoprotein
HMPJKFDJ_00925 7.5e-10
HMPJKFDJ_00926 1e-45
HMPJKFDJ_00927 2.3e-75 K TetR family transcriptional regulator
HMPJKFDJ_00928 8.4e-81 Q Methyltransferase domain
HMPJKFDJ_00929 2.1e-131 ybbA S Putative esterase
HMPJKFDJ_00930 5.1e-171 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HMPJKFDJ_00931 5.8e-135 fecE 3.6.3.34 HP ABC transporter
HMPJKFDJ_00932 5.5e-160 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMPJKFDJ_00933 3.6e-129 V CAAX protease self-immunity
HMPJKFDJ_00934 2.3e-153 S Domain of unknown function (DUF4300)
HMPJKFDJ_00935 2.2e-141 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
HMPJKFDJ_00936 1.6e-26 P Hemerythrin HHE cation binding domain protein
HMPJKFDJ_00937 8.9e-161 5.2.1.8 G hydrolase
HMPJKFDJ_00938 1.6e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMPJKFDJ_00939 1.3e-210 MA20_36090 S Protein of unknown function (DUF2974)
HMPJKFDJ_00940 1.4e-133 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMPJKFDJ_00941 4.2e-32 S Phage derived protein Gp49-like (DUF891)
HMPJKFDJ_00942 1.7e-45 K Helix-turn-helix domain
HMPJKFDJ_00943 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HMPJKFDJ_00944 3.5e-178 S SIR2-like domain
HMPJKFDJ_00945 6e-295 S Domain of unknown function DUF87
HMPJKFDJ_00946 3.5e-17 endA S DNA/RNA non-specific endonuclease
HMPJKFDJ_00947 6.7e-128 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HMPJKFDJ_00948 1.5e-261 S KAP family P-loop domain
HMPJKFDJ_00949 1.1e-130 S Protein conserved in bacteria
HMPJKFDJ_00950 6.2e-304 hsdM 2.1.1.72 V type I restriction-modification system
HMPJKFDJ_00951 6.1e-52
HMPJKFDJ_00952 8.7e-193 higA K Pfam:DUF955
HMPJKFDJ_00953 3.9e-148 S double-stranded DNA endodeoxyribonuclease activity
HMPJKFDJ_00954 0.0 2.4.1.21 GT5 M Right handed beta helix region
HMPJKFDJ_00955 6e-172 spd F DNA RNA non-specific endonuclease
HMPJKFDJ_00956 7.7e-92 lemA S LemA family
HMPJKFDJ_00957 4e-135 htpX O Belongs to the peptidase M48B family
HMPJKFDJ_00958 2.6e-115 sirR K iron dependent repressor
HMPJKFDJ_00959 3.3e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
HMPJKFDJ_00960 8.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
HMPJKFDJ_00961 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
HMPJKFDJ_00962 4.7e-74 S Psort location CytoplasmicMembrane, score
HMPJKFDJ_00963 6.2e-64 S Domain of unknown function (DUF4430)
HMPJKFDJ_00964 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HMPJKFDJ_00965 7.1e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HMPJKFDJ_00966 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HMPJKFDJ_00967 3.6e-172 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HMPJKFDJ_00968 1.7e-114 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HMPJKFDJ_00969 9.3e-92 dps P Belongs to the Dps family
HMPJKFDJ_00970 5.2e-83 perR P Belongs to the Fur family
HMPJKFDJ_00971 2.4e-27 yqgQ S protein conserved in bacteria
HMPJKFDJ_00972 1.9e-178 glk 2.7.1.2 G Glucokinase
HMPJKFDJ_00973 0.0 typA T GTP-binding protein TypA
HMPJKFDJ_00975 1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMPJKFDJ_00976 8.6e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMPJKFDJ_00977 2.2e-133 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMPJKFDJ_00978 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMPJKFDJ_00979 1.7e-238 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMPJKFDJ_00980 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HMPJKFDJ_00981 3.2e-101 sepF D cell septum assembly
HMPJKFDJ_00982 6.5e-30 yggT D integral membrane protein
HMPJKFDJ_00983 5e-145 ylmH S conserved protein, contains S4-like domain
HMPJKFDJ_00984 8.4e-138 divIVA D Cell division initiation protein
HMPJKFDJ_00985 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMPJKFDJ_00986 7.4e-236 L Transposase
HMPJKFDJ_00987 2.5e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMPJKFDJ_00988 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMPJKFDJ_00989 6.5e-34 nrdH O Glutaredoxin
HMPJKFDJ_00990 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HMPJKFDJ_00991 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
HMPJKFDJ_00992 6.5e-218 icd 1.1.1.42 C Isocitrate dehydrogenase
HMPJKFDJ_00993 3e-38 ptsH G phosphocarrier protein Hpr
HMPJKFDJ_00994 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMPJKFDJ_00995 1.9e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HMPJKFDJ_00996 6.1e-162 XK27_05670 S Putative esterase
HMPJKFDJ_00997 9.6e-151 XK27_05675 S Esterase
HMPJKFDJ_00998 6.6e-223 XK27_05680 6.3.2.4 M carbamoylphosphate synthase large subunit
HMPJKFDJ_00999 5.7e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
HMPJKFDJ_01000 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HMPJKFDJ_01001 0.0 uup S abc transporter atp-binding protein
HMPJKFDJ_01002 2.7e-39 MA20_06245 S yiaA/B two helix domain
HMPJKFDJ_01003 7.4e-132 pip 1.11.1.10 S Alpha beta hydrolase
HMPJKFDJ_01004 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMPJKFDJ_01005 5.3e-147 cobQ S glutamine amidotransferase
HMPJKFDJ_01006 3.8e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HMPJKFDJ_01007 3.9e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMPJKFDJ_01008 9.9e-164 ybbR S Protein conserved in bacteria
HMPJKFDJ_01009 7.4e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMPJKFDJ_01010 4.5e-65 gtrA S GtrA-like protein
HMPJKFDJ_01011 1.7e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMPJKFDJ_01012 7.1e-144 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMPJKFDJ_01013 4e-145 zupT P Mediates zinc uptake. May also transport other divalent cations
HMPJKFDJ_01014 1.3e-199 yurR 1.4.5.1 E oxidoreductase
HMPJKFDJ_01015 1.9e-258 S phospholipase Carboxylesterase
HMPJKFDJ_01016 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMPJKFDJ_01017 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HMPJKFDJ_01018 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMPJKFDJ_01020 1.7e-30 KT response to antibiotic
HMPJKFDJ_01021 2.2e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
HMPJKFDJ_01022 5.3e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
HMPJKFDJ_01023 1.4e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMPJKFDJ_01024 1.8e-116 ylfI S tigr01906
HMPJKFDJ_01025 9.3e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HMPJKFDJ_01026 6.3e-219 V MatE
HMPJKFDJ_01027 1e-33
HMPJKFDJ_01028 6.2e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HMPJKFDJ_01029 7.5e-62 XK27_08085
HMPJKFDJ_01030 1.8e-190 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMPJKFDJ_01031 1.3e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMPJKFDJ_01032 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMPJKFDJ_01033 7.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMPJKFDJ_01034 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HMPJKFDJ_01035 2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMPJKFDJ_01036 4.8e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMPJKFDJ_01037 2.1e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMPJKFDJ_01038 4e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMPJKFDJ_01039 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HMPJKFDJ_01042 4.2e-92 XK27_05505 S Psort location CytoplasmicMembrane, score
HMPJKFDJ_01043 2.2e-145 P molecular chaperone
HMPJKFDJ_01044 2.1e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
HMPJKFDJ_01045 1.1e-176 XK27_08075 M glycosyl transferase family 2
HMPJKFDJ_01046 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMPJKFDJ_01047 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMPJKFDJ_01048 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HMPJKFDJ_01049 1.9e-227 rodA D Belongs to the SEDS family
HMPJKFDJ_01050 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HMPJKFDJ_01051 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HMPJKFDJ_01054 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMPJKFDJ_01056 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
HMPJKFDJ_01057 5.3e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HMPJKFDJ_01058 5.8e-137 yfeJ 6.3.5.2 F glutamine amidotransferase
HMPJKFDJ_01059 2.3e-181 clcA_2 P Chloride transporter, ClC family
HMPJKFDJ_01060 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HMPJKFDJ_01061 1.2e-94 S Protein of unknown function (DUF1697)
HMPJKFDJ_01062 8e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMPJKFDJ_01063 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMPJKFDJ_01064 1.3e-249 V Glucan-binding protein C
HMPJKFDJ_01065 9.4e-74 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HMPJKFDJ_01066 6.8e-220 XK27_05470 E Methionine synthase
HMPJKFDJ_01067 1.8e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMPJKFDJ_01068 4.2e-232 T PhoQ Sensor
HMPJKFDJ_01069 1.6e-120 KT Transcriptional regulatory protein, C terminal
HMPJKFDJ_01070 2.5e-147 S TraX protein
HMPJKFDJ_01071 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMPJKFDJ_01072 1.1e-150 dprA LU DNA protecting protein DprA
HMPJKFDJ_01073 4e-138 GK ROK family
HMPJKFDJ_01074 1.6e-124 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMPJKFDJ_01075 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMPJKFDJ_01076 4e-127 K DNA-binding helix-turn-helix protein
HMPJKFDJ_01077 7.5e-86 niaR S small molecule binding protein (contains 3H domain)
HMPJKFDJ_01078 5.3e-87
HMPJKFDJ_01079 8.5e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMPJKFDJ_01080 4.9e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMPJKFDJ_01081 8.5e-125 gntR1 K transcriptional
HMPJKFDJ_01082 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMPJKFDJ_01083 7.6e-95
HMPJKFDJ_01084 1.8e-56 V ABC-2 type transporter
HMPJKFDJ_01085 2e-155 V AAA domain, putative AbiEii toxin, Type IV TA system
HMPJKFDJ_01086 7.9e-188 adhP 1.1.1.1 C alcohol dehydrogenase
HMPJKFDJ_01087 2.1e-42
HMPJKFDJ_01088 2e-51
HMPJKFDJ_01089 2.6e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMPJKFDJ_01090 6.7e-156 aatB ET ABC transporter substrate-binding protein
HMPJKFDJ_01091 3.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPJKFDJ_01092 1.4e-105 artQ P ABC transporter (Permease
HMPJKFDJ_01093 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
HMPJKFDJ_01094 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMPJKFDJ_01095 2.2e-165 cpsY K Transcriptional regulator
HMPJKFDJ_01096 3.9e-87 L Transposase
HMPJKFDJ_01097 1.3e-113 nudL L hydrolase
HMPJKFDJ_01098 6.3e-54 K transcriptional regulator, PadR family
HMPJKFDJ_01099 6.8e-59 XK27_06920 S Protein of unknown function (DUF1700)
HMPJKFDJ_01100 7.4e-107 S Putative adhesin
HMPJKFDJ_01101 1.6e-159 XK27_06930 V domain protein
HMPJKFDJ_01102 9.9e-97 XK27_06935 K transcriptional regulator
HMPJKFDJ_01103 4.1e-54 ypaA M Membrane
HMPJKFDJ_01104 1.9e-10
HMPJKFDJ_01106 1.4e-149 V Abi-like protein
HMPJKFDJ_01108 8.5e-26
HMPJKFDJ_01109 3e-12 arpU S Transcriptional regulator, ArpU family
HMPJKFDJ_01110 4.6e-13
HMPJKFDJ_01112 9.4e-47 S Virulence-associated protein E
HMPJKFDJ_01113 2.4e-129 KL Phage plasmid primase P4 family
HMPJKFDJ_01114 9e-22
HMPJKFDJ_01115 7.2e-15
HMPJKFDJ_01120 7.5e-21 K TRANSCRIPTIONal
HMPJKFDJ_01121 3.2e-40 K Helix-turn-helix
HMPJKFDJ_01122 1.2e-184 sip L Belongs to the 'phage' integrase family
HMPJKFDJ_01123 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMPJKFDJ_01124 1.8e-47 veg S Biofilm formation stimulator VEG
HMPJKFDJ_01125 1.7e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMPJKFDJ_01126 2.2e-73 rplI J binds to the 23S rRNA
HMPJKFDJ_01127 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMPJKFDJ_01128 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMPJKFDJ_01129 4.2e-99 yvbG U UPF0056 membrane protein
HMPJKFDJ_01130 5.6e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMPJKFDJ_01131 0.0 S Bacterial membrane protein, YfhO
HMPJKFDJ_01132 1.3e-31 isaA GH23 M Immunodominant staphylococcal antigen A
HMPJKFDJ_01133 1.5e-19 isaA GH23 M Immunodominant staphylococcal antigen A
HMPJKFDJ_01134 9.8e-63 lytE M LysM domain protein
HMPJKFDJ_01135 8.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMPJKFDJ_01136 1.6e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMPJKFDJ_01137 2.4e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMPJKFDJ_01138 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMPJKFDJ_01139 1.2e-131 S sequence-specific DNA binding
HMPJKFDJ_01140 2.2e-235 ymfH S Peptidase M16
HMPJKFDJ_01141 2.9e-232 ymfF S Peptidase M16
HMPJKFDJ_01142 8.9e-60 yaaA S S4 domain protein YaaA
HMPJKFDJ_01143 1e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMPJKFDJ_01144 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HMPJKFDJ_01145 2.5e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HMPJKFDJ_01146 1.6e-152 yvjA S membrane
HMPJKFDJ_01147 1.1e-305 ybiT S abc transporter atp-binding protein
HMPJKFDJ_01148 0.0 XK27_10405 S Bacterial membrane protein YfhO
HMPJKFDJ_01152 2.2e-117 yoaK S Protein of unknown function (DUF1275)
HMPJKFDJ_01153 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMPJKFDJ_01154 1.5e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HMPJKFDJ_01155 3.2e-133 parB K Belongs to the ParB family
HMPJKFDJ_01156 8.5e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMPJKFDJ_01157 1.6e-197 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMPJKFDJ_01158 1.1e-29 yyzM S Protein conserved in bacteria
HMPJKFDJ_01159 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMPJKFDJ_01160 5.7e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMPJKFDJ_01161 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMPJKFDJ_01162 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HMPJKFDJ_01163 3e-60 divIC D Septum formation initiator
HMPJKFDJ_01165 1.3e-238 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HMPJKFDJ_01166 5.3e-234 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMPJKFDJ_01167 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMPJKFDJ_01168 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMPJKFDJ_01169 1e-38 gcvR T UPF0237 protein
HMPJKFDJ_01170 2.3e-243 XK27_08635 S UPF0210 protein
HMPJKFDJ_01171 1.4e-130 ais G Phosphoglycerate mutase
HMPJKFDJ_01172 2.3e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HMPJKFDJ_01173 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
HMPJKFDJ_01174 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMPJKFDJ_01175 1.3e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMPJKFDJ_01176 6e-303 dnaK O Heat shock 70 kDa protein
HMPJKFDJ_01178 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMPJKFDJ_01179 1.3e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMPJKFDJ_01180 5.8e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HMPJKFDJ_01181 1.7e-79 hmpT S cog cog4720
HMPJKFDJ_01182 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMPJKFDJ_01183 3.2e-272 pepV 3.5.1.18 E Dipeptidase
HMPJKFDJ_01184 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMPJKFDJ_01185 3.9e-90 yybC
HMPJKFDJ_01186 6.1e-82 XK27_03610 K Gnat family
HMPJKFDJ_01187 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMPJKFDJ_01188 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMPJKFDJ_01189 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMPJKFDJ_01190 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMPJKFDJ_01191 9.4e-17 M LysM domain
HMPJKFDJ_01192 1.5e-86 ebsA S Family of unknown function (DUF5322)
HMPJKFDJ_01193 1.3e-232 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMPJKFDJ_01194 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HMPJKFDJ_01195 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMPJKFDJ_01196 2.8e-224 G COG0457 FOG TPR repeat
HMPJKFDJ_01197 4.3e-177 yubA S permease
HMPJKFDJ_01198 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HMPJKFDJ_01199 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HMPJKFDJ_01200 9.6e-23
HMPJKFDJ_01201 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMPJKFDJ_01202 4.1e-89 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
HMPJKFDJ_01203 1.6e-298 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMPJKFDJ_01204 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMPJKFDJ_01205 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMPJKFDJ_01206 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMPJKFDJ_01207 4.6e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMPJKFDJ_01208 2.8e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HMPJKFDJ_01209 6.9e-103 ybhL S Belongs to the BI1 family
HMPJKFDJ_01210 2.4e-12 ycdA S Domain of unknown function (DUF4352)
HMPJKFDJ_01211 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMPJKFDJ_01212 1.4e-90 K transcriptional regulator
HMPJKFDJ_01213 1.6e-36 yneF S UPF0154 protein
HMPJKFDJ_01214 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMPJKFDJ_01215 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMPJKFDJ_01216 3.9e-98 XK27_09740 S Phosphoesterase
HMPJKFDJ_01217 8.3e-87 ykuL S CBS domain
HMPJKFDJ_01218 7.2e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HMPJKFDJ_01219 2.6e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMPJKFDJ_01220 3.8e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMPJKFDJ_01221 4.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMPJKFDJ_01222 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
HMPJKFDJ_01223 4.2e-259 trkH P Cation transport protein
HMPJKFDJ_01224 2.6e-247 trkA P Potassium transporter peripheral membrane component
HMPJKFDJ_01225 6.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMPJKFDJ_01226 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMPJKFDJ_01227 3.7e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HMPJKFDJ_01228 7.1e-156 K sequence-specific DNA binding
HMPJKFDJ_01229 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMPJKFDJ_01230 3.2e-53 yhaI L Membrane
HMPJKFDJ_01231 8.7e-40 S Domain of unknown function (DUF4173)
HMPJKFDJ_01232 6.8e-95 ureI S AmiS/UreI family transporter
HMPJKFDJ_01233 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HMPJKFDJ_01234 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HMPJKFDJ_01235 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HMPJKFDJ_01236 4.3e-77 ureE O enzyme active site formation
HMPJKFDJ_01237 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HMPJKFDJ_01238 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HMPJKFDJ_01239 2.6e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HMPJKFDJ_01240 1.3e-176 cbiM P biosynthesis protein CbiM
HMPJKFDJ_01241 1.4e-136 P cobalt transport protein
HMPJKFDJ_01242 5.3e-130 cbiO P ABC transporter
HMPJKFDJ_01243 6.3e-138 ET ABC transporter substrate-binding protein
HMPJKFDJ_01244 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
HMPJKFDJ_01245 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HMPJKFDJ_01246 1.9e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMPJKFDJ_01247 8e-99 metI P ABC transporter (Permease
HMPJKFDJ_01248 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HMPJKFDJ_01249 6.1e-120 ktrA P COG0569 K transport systems, NAD-binding component
HMPJKFDJ_01250 1.9e-237 P COG0168 Trk-type K transport systems, membrane components
HMPJKFDJ_01251 2.6e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HMPJKFDJ_01252 1.8e-90 yceD K metal-binding, possibly nucleic acid-binding protein
HMPJKFDJ_01253 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMPJKFDJ_01254 3.7e-282 T PhoQ Sensor
HMPJKFDJ_01255 1.4e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMPJKFDJ_01256 1.6e-216 dnaB L Replication initiation and membrane attachment
HMPJKFDJ_01257 1.5e-166 dnaI L Primosomal protein DnaI
HMPJKFDJ_01258 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMPJKFDJ_01259 1.1e-102
HMPJKFDJ_01260 2e-228 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMPJKFDJ_01261 2.5e-62 manO S protein conserved in bacteria
HMPJKFDJ_01262 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
HMPJKFDJ_01263 2.6e-117 manM G pts system
HMPJKFDJ_01264 4.9e-174 manL 2.7.1.191 G pts system
HMPJKFDJ_01265 2e-67 manO S Protein conserved in bacteria
HMPJKFDJ_01266 1.9e-164 manN G PTS system mannose fructose sorbose family IID component
HMPJKFDJ_01267 4.7e-135 manY G pts system
HMPJKFDJ_01268 1.6e-169 manL 2.7.1.191 G pts system
HMPJKFDJ_01269 1.2e-126 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HMPJKFDJ_01270 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HMPJKFDJ_01271 1.6e-247 pbuO S permease
HMPJKFDJ_01272 4.2e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HMPJKFDJ_01273 1.9e-89 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
HMPJKFDJ_01274 2e-212 brpA K Transcriptional
HMPJKFDJ_01275 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
HMPJKFDJ_01276 2.4e-196 nusA K Participates in both transcription termination and antitermination
HMPJKFDJ_01277 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HMPJKFDJ_01278 8e-42 ylxQ J ribosomal protein
HMPJKFDJ_01279 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMPJKFDJ_01280 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMPJKFDJ_01281 8.5e-99 yvdD 3.2.2.10 S Belongs to the LOG family
HMPJKFDJ_01282 1.9e-272 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMPJKFDJ_01283 2.7e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HMPJKFDJ_01284 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HMPJKFDJ_01285 9.7e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
HMPJKFDJ_01286 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HMPJKFDJ_01287 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HMPJKFDJ_01288 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
HMPJKFDJ_01289 1.3e-111 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMPJKFDJ_01290 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMPJKFDJ_01291 6.2e-76 ylbF S Belongs to the UPF0342 family
HMPJKFDJ_01292 1.9e-46 ylbG S UPF0298 protein
HMPJKFDJ_01293 2.8e-213 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HMPJKFDJ_01294 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
HMPJKFDJ_01295 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
HMPJKFDJ_01296 3.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HMPJKFDJ_01297 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HMPJKFDJ_01298 5.4e-113 acuB S CBS domain
HMPJKFDJ_01299 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMPJKFDJ_01300 2.4e-110 yvyE 3.4.13.9 S YigZ family
HMPJKFDJ_01301 6.5e-251 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HMPJKFDJ_01302 7.7e-83 comFC K competence protein
HMPJKFDJ_01303 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMPJKFDJ_01304 0.0 3.6.3.8 P cation transport ATPase
HMPJKFDJ_01305 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HMPJKFDJ_01307 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMPJKFDJ_01308 1.6e-165 metF 1.5.1.20 E reductase
HMPJKFDJ_01309 1e-105 S Domain of unknown function (DUF1803)
HMPJKFDJ_01310 6e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
HMPJKFDJ_01313 1.9e-240 T PhoQ Sensor
HMPJKFDJ_01314 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMPJKFDJ_01315 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMPJKFDJ_01316 2.1e-112 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HMPJKFDJ_01317 1.8e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMPJKFDJ_01318 6.4e-94 panT S ECF transporter, substrate-specific component
HMPJKFDJ_01319 3.8e-91 panT S Psort location CytoplasmicMembrane, score
HMPJKFDJ_01320 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HMPJKFDJ_01326 7.2e-65 L Transposase (IS116 IS110 IS902 family)
HMPJKFDJ_01332 1.2e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMPJKFDJ_01333 7.1e-178 bglC K Transcriptional regulator
HMPJKFDJ_01334 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HMPJKFDJ_01335 3.2e-81 yecS P ABC transporter (Permease
HMPJKFDJ_01336 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
HMPJKFDJ_01337 3.3e-240 nylA 3.5.1.4 J Belongs to the amidase family
HMPJKFDJ_01338 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMPJKFDJ_01339 5.3e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMPJKFDJ_01340 4.5e-177 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMPJKFDJ_01341 3.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HMPJKFDJ_01342 2e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HMPJKFDJ_01343 1.8e-142 S TraX protein
HMPJKFDJ_01344 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HMPJKFDJ_01345 3.3e-270 S Psort location CytoplasmicMembrane, score
HMPJKFDJ_01346 4.3e-234 dinF V Mate efflux family protein
HMPJKFDJ_01347 8.1e-182 yclQ P ABC-type enterochelin transport system, periplasmic component
HMPJKFDJ_01348 4e-170 S von Willebrand factor (vWF) type A domain
HMPJKFDJ_01349 5.8e-112 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HMPJKFDJ_01350 2.1e-132 2.4.2.3 F Phosphorylase superfamily
HMPJKFDJ_01351 5.3e-145 G protein with an alpha beta hydrolase fold
HMPJKFDJ_01352 1.5e-180 S Hydrolases of the alpha beta superfamily
HMPJKFDJ_01353 1.6e-157 K Transcriptional regulator
HMPJKFDJ_01354 3.8e-111 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HMPJKFDJ_01355 8.1e-32 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
HMPJKFDJ_01356 6.7e-201 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HMPJKFDJ_01357 3.3e-161 czcD P cation diffusion facilitator family transporter
HMPJKFDJ_01358 1.7e-96 K Transcriptional regulator, TetR family
HMPJKFDJ_01359 7.2e-67 S Protein of unknown function with HXXEE motif
HMPJKFDJ_01360 4.9e-12
HMPJKFDJ_01361 2.9e-33 pnuC H nicotinamide mononucleotide transporter
HMPJKFDJ_01362 4.4e-112 tnp L DDE domain
HMPJKFDJ_01363 3.3e-149 cbiO2 P ABC transporter, ATP-binding protein
HMPJKFDJ_01364 2e-157 P ATPase activity
HMPJKFDJ_01365 3.7e-132 cbiQ P Cobalt transport protein
HMPJKFDJ_01366 4.1e-91 2.7.7.65 T Psort location CytoplasmicMembrane, score
HMPJKFDJ_01367 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HMPJKFDJ_01368 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMPJKFDJ_01369 3.6e-230 cinA 3.5.1.42 S Belongs to the CinA family
HMPJKFDJ_01370 1.1e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HMPJKFDJ_01371 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMPJKFDJ_01373 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMPJKFDJ_01375 4.9e-70 K LytTr DNA-binding domain
HMPJKFDJ_01376 1e-78 S Protein of unknown function (DUF3021)
HMPJKFDJ_01377 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMPJKFDJ_01378 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HMPJKFDJ_01379 4.5e-68 argR K Regulates arginine biosynthesis genes
HMPJKFDJ_01380 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HMPJKFDJ_01381 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMPJKFDJ_01383 7.3e-135 J Domain of unknown function (DUF4041)
HMPJKFDJ_01384 2.5e-33
HMPJKFDJ_01385 1.8e-173 1.1.1.169 H Ketopantoate reductase
HMPJKFDJ_01386 2.7e-202 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMPJKFDJ_01387 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMPJKFDJ_01388 6.1e-238 purD 6.3.4.13 F Belongs to the GARS family
HMPJKFDJ_01389 1.6e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HMPJKFDJ_01391 7.6e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMPJKFDJ_01392 6.1e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HMPJKFDJ_01393 2.1e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMPJKFDJ_01394 5.9e-175
HMPJKFDJ_01395 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMPJKFDJ_01396 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HMPJKFDJ_01397 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMPJKFDJ_01398 1.2e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMPJKFDJ_01399 5.5e-141 recO L Involved in DNA repair and RecF pathway recombination
HMPJKFDJ_01400 1.1e-217 araT 2.6.1.1 E Aminotransferase
HMPJKFDJ_01401 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMPJKFDJ_01403 3e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HMPJKFDJ_01404 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
HMPJKFDJ_01405 1e-176 S oxidoreductase
HMPJKFDJ_01406 2.8e-187 murN 2.3.2.16 V FemAB family
HMPJKFDJ_01407 3.8e-117 M Pfam SNARE associated Golgi protein
HMPJKFDJ_01408 4.2e-107 S Domain of Unknown Function with PDB structure (DUF3862)
HMPJKFDJ_01411 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
HMPJKFDJ_01414 4.8e-16 S Protein of unknown function (DUF2969)
HMPJKFDJ_01415 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
HMPJKFDJ_01416 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMPJKFDJ_01417 4.9e-11
HMPJKFDJ_01419 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMPJKFDJ_01420 2.1e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMPJKFDJ_01421 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
HMPJKFDJ_01422 2.2e-30 S Domain of unknown function (DUF1912)
HMPJKFDJ_01423 3.3e-172 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HMPJKFDJ_01424 4.9e-249 mmuP E amino acid
HMPJKFDJ_01425 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HMPJKFDJ_01426 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMPJKFDJ_01427 9.7e-22
HMPJKFDJ_01428 5.8e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMPJKFDJ_01429 3.8e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMPJKFDJ_01430 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HMPJKFDJ_01431 6.8e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMPJKFDJ_01432 2.8e-35
HMPJKFDJ_01433 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMPJKFDJ_01434 1e-162 yxeN P ABC transporter (Permease
HMPJKFDJ_01435 2.1e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
HMPJKFDJ_01436 5e-10 S Protein of unknown function (DUF4059)
HMPJKFDJ_01437 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMPJKFDJ_01438 1.3e-91 rsmD 2.1.1.171 L Methyltransferase
HMPJKFDJ_01439 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMPJKFDJ_01440 3.2e-187 ylbL T Belongs to the peptidase S16 family
HMPJKFDJ_01441 5.4e-183 yhcC S radical SAM protein
HMPJKFDJ_01442 2.7e-97 ytqB J (SAM)-dependent
HMPJKFDJ_01444 0.0 yjcE P NhaP-type Na H and K H antiporters
HMPJKFDJ_01445 5.6e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HMPJKFDJ_01446 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HMPJKFDJ_01447 1.5e-10 MU outer membrane autotransporter barrel domain protein
HMPJKFDJ_01448 3.9e-158 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMPJKFDJ_01450 9e-75 XK27_03180 T universal stress protein
HMPJKFDJ_01451 3.1e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HMPJKFDJ_01452 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HMPJKFDJ_01453 6.8e-101 pncA Q isochorismatase
HMPJKFDJ_01454 1e-294 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMPJKFDJ_01455 2.9e-57 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
HMPJKFDJ_01456 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMPJKFDJ_01457 2.2e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMPJKFDJ_01458 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMPJKFDJ_01459 1.4e-65
HMPJKFDJ_01460 1.6e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HMPJKFDJ_01461 1.4e-98 yqeG S hydrolase of the HAD superfamily
HMPJKFDJ_01462 5.4e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HMPJKFDJ_01463 7.7e-49 yhbY J RNA-binding protein
HMPJKFDJ_01464 3.5e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMPJKFDJ_01465 1.8e-104 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HMPJKFDJ_01466 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMPJKFDJ_01467 1.2e-137 yqeM Q Methyltransferase domain protein
HMPJKFDJ_01468 1.4e-195 ylbM S Belongs to the UPF0348 family
HMPJKFDJ_01469 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
HMPJKFDJ_01471 1.6e-103
HMPJKFDJ_01473 4.1e-07
HMPJKFDJ_01474 8.6e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HMPJKFDJ_01475 2.4e-130 ecsA V abc transporter atp-binding protein
HMPJKFDJ_01476 3e-174 ecsB U Bacterial ABC transporter protein EcsB
HMPJKFDJ_01477 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
HMPJKFDJ_01478 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMPJKFDJ_01480 2.6e-222 ytfP S Flavoprotein
HMPJKFDJ_01481 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HMPJKFDJ_01482 9e-62 XK27_02560 S cog cog2151
HMPJKFDJ_01483 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
HMPJKFDJ_01484 1e-102 dnaQ 2.7.7.7 L DNA polymerase III
HMPJKFDJ_01485 7.8e-121 K transcriptional regulator, MerR family
HMPJKFDJ_01486 1.6e-235 L Transposase
HMPJKFDJ_01487 0.0 V ABC transporter (Permease
HMPJKFDJ_01488 1.6e-123 V abc transporter atp-binding protein
HMPJKFDJ_01490 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMPJKFDJ_01491 4.1e-44
HMPJKFDJ_01492 0.0 ctpE P E1-E2 ATPase
HMPJKFDJ_01493 3.4e-59
HMPJKFDJ_01494 3.4e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
HMPJKFDJ_01495 6.9e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMPJKFDJ_01496 2.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HMPJKFDJ_01497 2.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMPJKFDJ_01498 3.6e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HMPJKFDJ_01499 1.1e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HMPJKFDJ_01500 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMPJKFDJ_01501 2.3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMPJKFDJ_01502 1.2e-73 copY K negative regulation of transcription, DNA-templated
HMPJKFDJ_01503 0.0 copA 3.6.3.54 P P-type ATPase
HMPJKFDJ_01504 1.4e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
HMPJKFDJ_01505 3.5e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMPJKFDJ_01506 6.6e-114 papP P ABC transporter (Permease
HMPJKFDJ_01507 1.3e-109 P ABC transporter (Permease
HMPJKFDJ_01508 3.4e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPJKFDJ_01509 3.7e-154 cjaA ET ABC transporter substrate-binding protein
HMPJKFDJ_01512 4.9e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMPJKFDJ_01513 1e-106 ywaF S integral membrane protein
HMPJKFDJ_01514 1.5e-299 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMPJKFDJ_01515 3.3e-98 thiT S Thiamine transporter
HMPJKFDJ_01516 3.3e-62 yjqA S Bacterial PH domain
HMPJKFDJ_01517 1.3e-152 corA P CorA-like protein
HMPJKFDJ_01518 5.4e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMPJKFDJ_01519 1.1e-40 yazA L endonuclease containing a URI domain
HMPJKFDJ_01520 3.3e-138 yabB 2.1.1.223 L Methyltransferase
HMPJKFDJ_01521 4.5e-137 nodB3 G deacetylase
HMPJKFDJ_01522 1.7e-142 plsC 2.3.1.51 I Acyltransferase
HMPJKFDJ_01523 3.7e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HMPJKFDJ_01524 0.0 comEC S Competence protein ComEC
HMPJKFDJ_01525 1.6e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMPJKFDJ_01526 1.8e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HMPJKFDJ_01527 3e-232 ytoI K transcriptional regulator containing CBS domains
HMPJKFDJ_01528 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HMPJKFDJ_01529 3.7e-163 rbn E Belongs to the UPF0761 family
HMPJKFDJ_01530 2.2e-85 ccl S cog cog4708
HMPJKFDJ_01531 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMPJKFDJ_01532 1.1e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HMPJKFDJ_01533 1.8e-173 yfjR K regulation of single-species biofilm formation
HMPJKFDJ_01535 4.9e-71 S QueT transporter
HMPJKFDJ_01536 9.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HMPJKFDJ_01538 1.1e-197 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMPJKFDJ_01539 2.2e-17 yjdB S Domain of unknown function (DUF4767)
HMPJKFDJ_01540 2.8e-165 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HMPJKFDJ_01541 7.6e-188 O protein import
HMPJKFDJ_01542 2.1e-129 agrA KT phosphorelay signal transduction system
HMPJKFDJ_01543 3.9e-197 2.7.13.3 T GHKL domain
HMPJKFDJ_01545 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMPJKFDJ_01546 1.5e-36 ylqC L Belongs to the UPF0109 family
HMPJKFDJ_01547 5.7e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMPJKFDJ_01548 0.0 ydaO E amino acid
HMPJKFDJ_01549 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
HMPJKFDJ_01550 3.2e-144 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HMPJKFDJ_01551 5.4e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HMPJKFDJ_01552 4.1e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMPJKFDJ_01553 1.7e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HMPJKFDJ_01554 9.5e-169 murB 1.3.1.98 M cell wall formation
HMPJKFDJ_01555 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMPJKFDJ_01556 1.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
HMPJKFDJ_01557 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
HMPJKFDJ_01558 4.8e-204 potD P spermidine putrescine ABC transporter
HMPJKFDJ_01559 7.3e-145 XK27_08050 O HflC and HflK could regulate a protease
HMPJKFDJ_01560 6.9e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
HMPJKFDJ_01561 1.7e-157 GK ROK family
HMPJKFDJ_01562 1.9e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMPJKFDJ_01563 1e-104 wecD M Acetyltransferase (GNAT) domain
HMPJKFDJ_01564 1.7e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMPJKFDJ_01565 2.7e-72 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HMPJKFDJ_01566 1e-57 arsC 1.20.4.1 P Belongs to the ArsC family
HMPJKFDJ_01568 1.6e-184 femA 2.3.2.10, 2.3.2.16 V FemAB family
HMPJKFDJ_01569 5.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMPJKFDJ_01570 2.8e-123 atpB C it plays a direct role in the translocation of protons across the membrane
HMPJKFDJ_01571 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMPJKFDJ_01572 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMPJKFDJ_01573 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMPJKFDJ_01574 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMPJKFDJ_01575 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMPJKFDJ_01576 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMPJKFDJ_01577 3.9e-216 ftsW D Belongs to the SEDS family
HMPJKFDJ_01578 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMPJKFDJ_01579 4.9e-134 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMPJKFDJ_01580 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMPJKFDJ_01582 2.4e-110 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMPJKFDJ_01583 1.7e-159 holB 2.7.7.7 L dna polymerase iii
HMPJKFDJ_01584 7.5e-133 yaaT S stage 0 sporulation protein
HMPJKFDJ_01585 1.2e-54 yabA L Involved in initiation control of chromosome replication
HMPJKFDJ_01586 3.6e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMPJKFDJ_01587 1.9e-228 amt P Ammonium Transporter
HMPJKFDJ_01588 1.9e-53 glnB K Belongs to the P(II) protein family
HMPJKFDJ_01589 7.8e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
HMPJKFDJ_01590 1.4e-142 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HMPJKFDJ_01591 5.2e-82 S Bacterial inner membrane protein
HMPJKFDJ_01592 1.8e-107 3.4.17.14, 3.5.1.28 NU amidase activity
HMPJKFDJ_01593 1.3e-293 nptA P COG1283 Na phosphate symporter
HMPJKFDJ_01594 8e-213 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMPJKFDJ_01595 5.3e-218 S membrane
HMPJKFDJ_01596 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMPJKFDJ_01597 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMPJKFDJ_01598 1.3e-38 ynzC S UPF0291 protein
HMPJKFDJ_01599 6.7e-254 cycA E permease
HMPJKFDJ_01600 4.6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
HMPJKFDJ_01601 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMPJKFDJ_01602 4.6e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMPJKFDJ_01606 2.6e-69 K Helix-turn-helix
HMPJKFDJ_01607 3.9e-43
HMPJKFDJ_01609 4e-167 fhuR K transcriptional regulator (lysR family)
HMPJKFDJ_01610 4.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMPJKFDJ_01611 7.2e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMPJKFDJ_01612 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMPJKFDJ_01613 1.6e-222 pyrP F uracil Permease
HMPJKFDJ_01614 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMPJKFDJ_01615 4.6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HMPJKFDJ_01616 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HMPJKFDJ_01617 1.9e-122 rsmJ 2.1.1.242 J Putative SAM-dependent methyltransferase
HMPJKFDJ_01618 8.8e-181 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMPJKFDJ_01619 2.9e-120 macB V ABC transporter, ATP-binding protein
HMPJKFDJ_01620 2.3e-210 V permease protein
HMPJKFDJ_01621 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMPJKFDJ_01622 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMPJKFDJ_01624 2.2e-274 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HMPJKFDJ_01625 0.0 mdlB V abc transporter atp-binding protein
HMPJKFDJ_01626 0.0 lmrA V abc transporter atp-binding protein
HMPJKFDJ_01627 1.9e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMPJKFDJ_01628 5.2e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMPJKFDJ_01629 1.5e-196 yceA S Belongs to the UPF0176 family
HMPJKFDJ_01630 3.9e-114 S VIT family
HMPJKFDJ_01631 3.6e-140 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMPJKFDJ_01632 2.8e-218 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HMPJKFDJ_01633 9.9e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HMPJKFDJ_01635 1e-145 E Alpha beta hydrolase
HMPJKFDJ_01636 1.3e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMPJKFDJ_01637 4.2e-153 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HMPJKFDJ_01638 5.1e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HMPJKFDJ_01639 3.9e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HMPJKFDJ_01640 2.3e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMPJKFDJ_01641 4e-241 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HMPJKFDJ_01642 3.6e-134 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HMPJKFDJ_01643 7.2e-116 cps4C M biosynthesis protein
HMPJKFDJ_01644 6.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
HMPJKFDJ_01645 2.8e-257 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HMPJKFDJ_01646 1.3e-126 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMPJKFDJ_01647 5.1e-161 licD M LICD family
HMPJKFDJ_01648 2e-163 S Glycosyl transferase family 2
HMPJKFDJ_01649 1.3e-204 M glycosyl transferase group 1
HMPJKFDJ_01650 3.4e-84
HMPJKFDJ_01651 1e-170 S glycosyl transferase family 2
HMPJKFDJ_01652 5.3e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMPJKFDJ_01653 0.0 M Polysaccharide biosynthesis protein
HMPJKFDJ_01654 1.7e-244 S Polysaccharide biosynthesis protein
HMPJKFDJ_01655 1.9e-65 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HMPJKFDJ_01656 3.5e-73 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HMPJKFDJ_01657 1.1e-107 pgm G Belongs to the phosphoglycerate mutase family
HMPJKFDJ_01658 1.1e-107 G Belongs to the phosphoglycerate mutase family
HMPJKFDJ_01659 6.2e-108 G Belongs to the phosphoglycerate mutase family
HMPJKFDJ_01660 3.6e-197 S hmm pf01594
HMPJKFDJ_01661 6.2e-287 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMPJKFDJ_01662 4.9e-39 S granule-associated protein
HMPJKFDJ_01663 2.4e-284 S unusual protein kinase
HMPJKFDJ_01664 2e-101 estA E Lysophospholipase L1 and related esterases
HMPJKFDJ_01665 5.1e-156 rssA S Phospholipase, patatin family
HMPJKFDJ_01666 5.2e-182 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HMPJKFDJ_01667 3.4e-247 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HMPJKFDJ_01668 3.3e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMPJKFDJ_01669 3.8e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMPJKFDJ_01670 7.5e-236 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMPJKFDJ_01671 0.0 S the current gene model (or a revised gene model) may contain a frame shift
HMPJKFDJ_01672 1.9e-234 2.7.13.3 T protein histidine kinase activity
HMPJKFDJ_01673 1.1e-215 hpk9 2.7.13.3 T protein histidine kinase activity
HMPJKFDJ_01674 7.8e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HMPJKFDJ_01675 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMPJKFDJ_01676 6e-215 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMPJKFDJ_01677 0.0 lpdA 1.8.1.4 C Dehydrogenase
HMPJKFDJ_01680 1.7e-111 serB 3.1.3.3 E phosphoserine phosphatase
HMPJKFDJ_01681 4.3e-303 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMPJKFDJ_01682 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMPJKFDJ_01683 1.4e-98 3.1.3.18 S IA, variant 1
HMPJKFDJ_01684 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HMPJKFDJ_01685 3.5e-56 lrgA S Effector of murein hydrolase LrgA
HMPJKFDJ_01686 2.2e-77 S AIPR protein
HMPJKFDJ_01687 1.5e-174 S hydrolase
HMPJKFDJ_01688 8.4e-23
HMPJKFDJ_01689 3e-136 M LysM domain
HMPJKFDJ_01690 7.5e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMPJKFDJ_01691 4.6e-09
HMPJKFDJ_01692 0.0 L helicase
HMPJKFDJ_01693 1.2e-64 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
HMPJKFDJ_01694 8.1e-11
HMPJKFDJ_01695 5.6e-234 mntH P H( )-stimulated, divalent metal cation uptake system
HMPJKFDJ_01696 3.1e-33 XK27_12190 S protein conserved in bacteria
HMPJKFDJ_01698 5.5e-87 bioY S biotin synthase
HMPJKFDJ_01699 7.5e-252 yegQ O Peptidase U32
HMPJKFDJ_01700 1.5e-177 yegQ O Peptidase U32
HMPJKFDJ_01702 3e-67 ytxH S General stress protein
HMPJKFDJ_01703 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMPJKFDJ_01704 6.2e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMPJKFDJ_01705 2e-166 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMPJKFDJ_01706 2.2e-41 pspC KT PspC domain
HMPJKFDJ_01707 0.0 yhgF K Transcriptional accessory protein
HMPJKFDJ_01709 2.4e-156 XK27_03015 S permease
HMPJKFDJ_01710 9.9e-149 ycgQ S TIGR03943 family
HMPJKFDJ_01711 1.2e-120 L Helix-turn-helix domain
HMPJKFDJ_01712 3.4e-33 3.4.24.40 U Large extracellular alpha-helical protein
HMPJKFDJ_01716 4.3e-242 agcS E (Alanine) symporter
HMPJKFDJ_01717 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMPJKFDJ_01718 4.3e-239 metY 2.5.1.49 E o-acetylhomoserine
HMPJKFDJ_01719 8.6e-139 S haloacid dehalogenase-like hydrolase
HMPJKFDJ_01720 3.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMPJKFDJ_01721 6.2e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HMPJKFDJ_01722 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
HMPJKFDJ_01723 4.2e-237 XK27_04775 S hemerythrin HHE cation binding domain
HMPJKFDJ_01724 1.5e-144 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMPJKFDJ_01725 1.1e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMPJKFDJ_01726 1.6e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMPJKFDJ_01727 1e-44 yktA S Belongs to the UPF0223 family
HMPJKFDJ_01728 1.9e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HMPJKFDJ_01729 1.5e-252 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HMPJKFDJ_01730 9e-156 pstS P phosphate
HMPJKFDJ_01731 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HMPJKFDJ_01732 1.2e-155 pstA P phosphate transport system permease
HMPJKFDJ_01733 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMPJKFDJ_01734 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMPJKFDJ_01735 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
HMPJKFDJ_01736 0.0 pepN 3.4.11.2 E aminopeptidase
HMPJKFDJ_01737 1.2e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HMPJKFDJ_01738 3.2e-186 lplA 6.3.1.20 H Lipoate-protein ligase
HMPJKFDJ_01739 7.5e-38
HMPJKFDJ_01740 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMPJKFDJ_01741 1.5e-299 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
HMPJKFDJ_01742 5.4e-165 malR K Transcriptional regulator
HMPJKFDJ_01743 3.9e-229 malX G ABC transporter
HMPJKFDJ_01744 1.6e-252 malF P ABC transporter (Permease
HMPJKFDJ_01745 1.3e-151 malG P ABC transporter (Permease
HMPJKFDJ_01746 4.7e-213 msmX P Belongs to the ABC transporter superfamily
HMPJKFDJ_01747 1.8e-24 tatA U protein secretion
HMPJKFDJ_01748 3.4e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMPJKFDJ_01749 4e-293 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HMPJKFDJ_01750 8.1e-232 ycdB P peroxidase
HMPJKFDJ_01751 2.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
HMPJKFDJ_01752 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMPJKFDJ_01753 4.4e-283 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
HMPJKFDJ_01754 1e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMPJKFDJ_01755 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
HMPJKFDJ_01756 4.4e-283 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HMPJKFDJ_01757 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMPJKFDJ_01758 2.6e-39 gpsB D regulation of cell shape
HMPJKFDJ_01759 8.9e-95 ypsA S Belongs to the UPF0398 family
HMPJKFDJ_01760 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMPJKFDJ_01761 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMPJKFDJ_01762 7.6e-255 pepC 3.4.22.40 E aminopeptidase
HMPJKFDJ_01763 1.1e-77 yhaI S Protein of unknown function (DUF805)
HMPJKFDJ_01764 4.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMPJKFDJ_01765 1.9e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMPJKFDJ_01766 1.3e-219 macB_2 V FtsX-like permease family
HMPJKFDJ_01767 8.7e-122 yhcA V abc transporter atp-binding protein
HMPJKFDJ_01768 4.5e-121 mta K Transcriptional
HMPJKFDJ_01769 1.8e-32 S Protein of unknown function (DUF3021)
HMPJKFDJ_01770 9e-75 K COG3279 Response regulator of the LytR AlgR family
HMPJKFDJ_01771 3.7e-122 cylB V ABC-2 type transporter
HMPJKFDJ_01772 8.9e-148 cylA V abc transporter atp-binding protein
HMPJKFDJ_01773 1.3e-35 yjdF S Protein of unknown function (DUF2992)
HMPJKFDJ_01774 3.7e-224 S COG1073 Hydrolases of the alpha beta superfamily
HMPJKFDJ_01775 7.9e-71 K transcriptional
HMPJKFDJ_01776 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMPJKFDJ_01777 3.6e-132 glcR K transcriptional regulator (DeoR family)
HMPJKFDJ_01778 7e-147 cof S Sucrose-6F-phosphate phosphohydrolase
HMPJKFDJ_01779 2.4e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HMPJKFDJ_01780 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HMPJKFDJ_01781 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
HMPJKFDJ_01782 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMPJKFDJ_01783 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMPJKFDJ_01784 2.6e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMPJKFDJ_01785 1.7e-54 S TM2 domain
HMPJKFDJ_01786 3.8e-48
HMPJKFDJ_01788 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMPJKFDJ_01789 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMPJKFDJ_01790 1.5e-141 cmpC S abc transporter atp-binding protein
HMPJKFDJ_01791 0.0 WQ51_06230 S ABC transporter
HMPJKFDJ_01792 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMPJKFDJ_01793 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMPJKFDJ_01794 5.5e-144 cdsA 2.7.7.41 S Belongs to the CDS family
HMPJKFDJ_01795 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMPJKFDJ_01796 2e-47 yajC U protein transport
HMPJKFDJ_01797 7.9e-126 yeeN K transcriptional regulatory protein
HMPJKFDJ_01798 4e-279 V ABC transporter
HMPJKFDJ_01799 1.1e-148 Z012_04635 K sequence-specific DNA binding
HMPJKFDJ_01800 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
HMPJKFDJ_01801 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
HMPJKFDJ_01802 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HMPJKFDJ_01803 5.3e-162 mleP2 S Membrane transport protein
HMPJKFDJ_01804 5.1e-129 adcB P ABC transporter (Permease
HMPJKFDJ_01805 2.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
HMPJKFDJ_01806 5.9e-71 adcR K transcriptional
HMPJKFDJ_01807 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMPJKFDJ_01808 6.2e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMPJKFDJ_01809 2.7e-26
HMPJKFDJ_01810 4.1e-167 oppF P Belongs to the ABC transporter superfamily
HMPJKFDJ_01811 6.6e-198 oppD P Belongs to the ABC transporter superfamily
HMPJKFDJ_01812 1.2e-164 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMPJKFDJ_01813 9.7e-161 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMPJKFDJ_01814 2.3e-311 oppA E ABC transporter substrate-binding protein
HMPJKFDJ_01815 1e-273 sufB O assembly protein SufB
HMPJKFDJ_01816 6.8e-72 nifU C SUF system FeS assembly protein, NifU family
HMPJKFDJ_01817 5.9e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMPJKFDJ_01818 6.3e-235 sufD O assembly protein SufD
HMPJKFDJ_01819 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HMPJKFDJ_01820 1.9e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
HMPJKFDJ_01821 2.7e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMPJKFDJ_01822 4.8e-18 S Protein of unknown function (DUF3021)
HMPJKFDJ_01823 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMPJKFDJ_01824 6.9e-276 glnP P ABC transporter
HMPJKFDJ_01825 2.2e-123 glnQ E abc transporter atp-binding protein
HMPJKFDJ_01826 2.3e-183 D nuclear chromosome segregation
HMPJKFDJ_01827 9.5e-85 V VanZ like family
HMPJKFDJ_01828 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMPJKFDJ_01829 7.1e-193 yhjX P Major Facilitator
HMPJKFDJ_01830 1.4e-110 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HMPJKFDJ_01831 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMPJKFDJ_01832 4.3e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HMPJKFDJ_01833 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HMPJKFDJ_01834 2.6e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMPJKFDJ_01835 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMPJKFDJ_01836 9.1e-83 nrdI F Belongs to the NrdI family
HMPJKFDJ_01837 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMPJKFDJ_01838 1e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMPJKFDJ_01839 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
HMPJKFDJ_01840 2.4e-75 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HMPJKFDJ_01841 2.4e-83 XK27_03960 S Protein of unknown function (DUF3013)
HMPJKFDJ_01842 1.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMPJKFDJ_01843 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMPJKFDJ_01844 1.8e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMPJKFDJ_01845 2.8e-140 ykuT M mechanosensitive ion channel
HMPJKFDJ_01846 5.9e-88 sigH K DNA-templated transcription, initiation
HMPJKFDJ_01847 3.5e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMPJKFDJ_01848 4.8e-114 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HMPJKFDJ_01849 5.9e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMPJKFDJ_01850 4.8e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMPJKFDJ_01851 2.1e-67 GnaT 2.5.1.16 K acetyltransferase
HMPJKFDJ_01852 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HMPJKFDJ_01853 9.9e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMPJKFDJ_01854 2.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HMPJKFDJ_01855 1.3e-125 dnaD
HMPJKFDJ_01856 2.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMPJKFDJ_01858 5.6e-07 KT response to antibiotic
HMPJKFDJ_01859 4.6e-236 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMPJKFDJ_01860 3.5e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMPJKFDJ_01861 1.7e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMPJKFDJ_01862 3.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HMPJKFDJ_01863 7e-72 argR K Regulates arginine biosynthesis genes
HMPJKFDJ_01864 4.6e-302 recN L May be involved in recombinational repair of damaged DNA
HMPJKFDJ_01865 9.3e-150 DegV S DegV family
HMPJKFDJ_01866 2.2e-162 ypmR E COG2755 Lysophospholipase L1 and related esterases
HMPJKFDJ_01867 6.2e-97 ypmS S Protein conserved in bacteria
HMPJKFDJ_01868 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMPJKFDJ_01870 6.2e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HMPJKFDJ_01871 2.3e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMPJKFDJ_01872 7.1e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMPJKFDJ_01873 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HMPJKFDJ_01874 3.5e-37 ysdA L Membrane
HMPJKFDJ_01875 5.6e-277 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMPJKFDJ_01876 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMPJKFDJ_01877 0.0 dnaE 2.7.7.7 L DNA polymerase
HMPJKFDJ_01878 1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMPJKFDJ_01879 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMPJKFDJ_01880 4.8e-31 L COG1943 Transposase and inactivated derivatives
HMPJKFDJ_01881 5.8e-19 S Domain of unknown function (DUF4649)
HMPJKFDJ_01882 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
HMPJKFDJ_01883 1.2e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HMPJKFDJ_01884 6.8e-136 XK27_08845 S abc transporter atp-binding protein
HMPJKFDJ_01885 9.2e-311 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMPJKFDJ_01886 1.3e-150 estA CE1 S Putative esterase
HMPJKFDJ_01887 2.1e-126 XK27_08875 O Zinc-dependent metalloprotease
HMPJKFDJ_01888 2.2e-18 XK27_08880
HMPJKFDJ_01889 1e-75 fld C Flavodoxin
HMPJKFDJ_01890 1e-271 clcA P Chloride transporter, ClC family
HMPJKFDJ_01891 1.8e-38 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HMPJKFDJ_01892 2.8e-211 XK27_05110 P Chloride transporter ClC family
HMPJKFDJ_01893 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMPJKFDJ_01895 3.9e-104 K cell adhesion
HMPJKFDJ_01896 6.9e-19 S YjcQ protein
HMPJKFDJ_01897 3.2e-15
HMPJKFDJ_01898 6.5e-21 WQ51_02665 S Protein of unknown function (DUF3042)
HMPJKFDJ_01899 1.6e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMPJKFDJ_01900 1.5e-86 ytsP 1.8.4.14 T GAF domain-containing protein
HMPJKFDJ_01901 3.7e-304 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMPJKFDJ_01902 8.1e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMPJKFDJ_01903 1.2e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMPJKFDJ_01904 1.7e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMPJKFDJ_01905 3.2e-136
HMPJKFDJ_01907 5.5e-250 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
HMPJKFDJ_01908 2e-208 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HMPJKFDJ_01910 1.3e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMPJKFDJ_01911 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
HMPJKFDJ_01912 6.5e-154 endA F DNA RNA non-specific endonuclease
HMPJKFDJ_01913 1.9e-116 gltJ P ABC transporter (Permease
HMPJKFDJ_01914 7.5e-144 peb1A ET Belongs to the bacterial solute-binding protein 3 family
HMPJKFDJ_01915 1e-128 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPJKFDJ_01916 5e-111 tcyB_2 P ABC transporter (permease)
HMPJKFDJ_01917 1.8e-85 gltJ P ABC transporter (Permease
HMPJKFDJ_01918 1.9e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMPJKFDJ_01919 2.7e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
HMPJKFDJ_01920 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMPJKFDJ_01921 2.4e-220 vicK 2.7.13.3 T Histidine kinase
HMPJKFDJ_01922 1.3e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HMPJKFDJ_01923 8.7e-57 S Protein of unknown function (DUF454)
HMPJKFDJ_01924 3.3e-16 L COG1943 Transposase and inactivated derivatives
HMPJKFDJ_01925 1.3e-205 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HMPJKFDJ_01926 2e-146 yidA S hydrolases of the HAD superfamily
HMPJKFDJ_01927 1.7e-159 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
HMPJKFDJ_01928 3.2e-141 XK27_00120 2.4.2.3 F Phosphorylase superfamily
HMPJKFDJ_01929 5.3e-68 ywiB S Domain of unknown function (DUF1934)
HMPJKFDJ_01930 0.0 pacL 3.6.3.8 P cation transport ATPase
HMPJKFDJ_01931 9.7e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMPJKFDJ_01932 6.4e-159 yjjH S Calcineurin-like phosphoesterase
HMPJKFDJ_01933 7.8e-205 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HMPJKFDJ_01934 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMPJKFDJ_01935 3.2e-124 ftsE D cell division ATP-binding protein FtsE
HMPJKFDJ_01936 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HMPJKFDJ_01937 2.3e-63 L Transposase (IS116 IS110 IS902 family)
HMPJKFDJ_01938 5.3e-212 mvaS 2.3.3.10 I synthase
HMPJKFDJ_01939 2.8e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HMPJKFDJ_01940 8.6e-78 K hmm pf08876
HMPJKFDJ_01941 5.2e-119 yqfA K protein, Hemolysin III
HMPJKFDJ_01942 4.1e-29 pspC KT PspC domain protein
HMPJKFDJ_01943 1.4e-198 S Protein of unknown function (DUF3114)
HMPJKFDJ_01944 3.2e-159 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMPJKFDJ_01945 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMPJKFDJ_01946 4e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HMPJKFDJ_01947 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HMPJKFDJ_01948 0.0 U protein secretion
HMPJKFDJ_01949 1.2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMPJKFDJ_01950 2e-26
HMPJKFDJ_01951 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HMPJKFDJ_01952 1.1e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMPJKFDJ_01953 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMPJKFDJ_01954 4.8e-54 S ABC-2 family transporter protein
HMPJKFDJ_01955 2.1e-149 V ABC transporter, ATP-binding protein
HMPJKFDJ_01956 2.1e-106 L Helix-turn-helix domain
HMPJKFDJ_01957 7.3e-61 S AIPR protein
HMPJKFDJ_01958 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMPJKFDJ_01959 1.1e-172 S Helix-hairpin-helix DNA-binding motif class 1
HMPJKFDJ_01960 1e-107 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMPJKFDJ_01961 4.3e-106 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HMPJKFDJ_01962 3e-14 coiA 3.6.4.12 S Competence protein
HMPJKFDJ_01963 2.6e-16 T peptidase
HMPJKFDJ_01964 3.7e-149 rarD S Transporter
HMPJKFDJ_01965 4.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMPJKFDJ_01966 9.9e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HMPJKFDJ_01967 1.6e-128 yxkH G deacetylase
HMPJKFDJ_01968 4.2e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HMPJKFDJ_01969 9.6e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HMPJKFDJ_01970 2.8e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMPJKFDJ_01971 8.5e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMPJKFDJ_01972 2.9e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HMPJKFDJ_01973 1.3e-142 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HMPJKFDJ_01974 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
HMPJKFDJ_01976 3e-232 2.7.13.3 T GHKL domain
HMPJKFDJ_01977 5.6e-135 agrA KT response regulator
HMPJKFDJ_01978 1.7e-07
HMPJKFDJ_01979 2.1e-67 agrA KT Response regulator of the LytR AlgR family
HMPJKFDJ_01980 3.9e-232 2.7.13.3 T GHKL domain
HMPJKFDJ_01981 3.2e-119
HMPJKFDJ_01982 1.2e-115 V ATPases associated with a variety of cellular activities
HMPJKFDJ_01984 3.6e-61 L PFAM transposase IS116 IS110 IS902 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)