ORF_ID e_value Gene_name EC_number CAZy COGs Description
LEPNOIND_00001 1.7e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LEPNOIND_00002 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEPNOIND_00003 1.3e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LEPNOIND_00004 7.1e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LEPNOIND_00005 1e-148 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LEPNOIND_00006 2.5e-155 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
LEPNOIND_00007 5.6e-109 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
LEPNOIND_00008 8.9e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LEPNOIND_00009 8.7e-173 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LEPNOIND_00010 1.7e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEPNOIND_00011 6.5e-142 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LEPNOIND_00012 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEPNOIND_00013 1.8e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LEPNOIND_00014 5.7e-269 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEPNOIND_00015 3.4e-177 KLT serine threonine protein kinase
LEPNOIND_00016 4.6e-129 yabS S protein containing a von Willebrand factor type A (vWA) domain
LEPNOIND_00017 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
LEPNOIND_00018 3.1e-224 citM C Citrate transporter
LEPNOIND_00020 3.3e-71 yabR J RNA binding protein (contains ribosomal protein S1 domain)
LEPNOIND_00021 1.6e-61 divIC D Septum formation initiator
LEPNOIND_00022 1.7e-67 yabQ S spore cortex biosynthesis protein
LEPNOIND_00023 6.7e-53 yabP S Sporulation protein YabP
LEPNOIND_00024 6.9e-104 MA20_20865 3.6.1.27 S SNARE associated Golgi protein
LEPNOIND_00025 2.4e-200 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LEPNOIND_00026 3e-87 2.3.1.128 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEPNOIND_00027 7.8e-177 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEPNOIND_00028 5.1e-119 S hydrolase
LEPNOIND_00029 9e-24 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LEPNOIND_00030 7.7e-277 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LEPNOIND_00031 2.5e-273 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEPNOIND_00032 5.2e-89 S Yip1 domain
LEPNOIND_00033 7.2e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEPNOIND_00034 1.3e-90 S Yip1 domain
LEPNOIND_00035 1.2e-94 spoVT K stage V sporulation protein
LEPNOIND_00036 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEPNOIND_00037 3.1e-39 yabK S Peptide ABC transporter permease
LEPNOIND_00038 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEPNOIND_00039 2.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LEPNOIND_00040 5.3e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEPNOIND_00041 1.7e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEPNOIND_00042 1.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LEPNOIND_00043 4.2e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
LEPNOIND_00044 1.7e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LEPNOIND_00045 4.8e-165 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEPNOIND_00046 3.3e-25 sspF S DNA topological change
LEPNOIND_00047 1.2e-39 veg S protein conserved in bacteria
LEPNOIND_00048 1.3e-162 yabG S peptidase
LEPNOIND_00049 5.7e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEPNOIND_00050 1.2e-115 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEPNOIND_00051 2.3e-216 rpfB GH23 T protein conserved in bacteria
LEPNOIND_00052 1.6e-148 tatD L hydrolase, TatD
LEPNOIND_00053 2.8e-270 S Protein of unknown function (DUF3298)
LEPNOIND_00054 5.9e-120 T protein histidine kinase activity
LEPNOIND_00055 1.6e-283 S ABC transporter
LEPNOIND_00057 1.6e-185 pelB 4.2.2.2 G Amb_all
LEPNOIND_00058 2e-82 K DNA-binding transcription factor activity
LEPNOIND_00059 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEPNOIND_00060 0.0 S Domain of unknown function DUF87
LEPNOIND_00061 1.9e-175 S NurA
LEPNOIND_00062 1.1e-43 abrB K COG2002 Regulators of stationary sporulation gene expression
LEPNOIND_00063 7e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEPNOIND_00064 1.5e-42 yazA L endonuclease containing a URI domain
LEPNOIND_00065 1.9e-135 yabB 2.1.1.223 S Conserved hypothetical protein 95
LEPNOIND_00066 8e-39 yabA L Involved in initiation control of chromosome replication
LEPNOIND_00067 4.4e-144 yaaT S stage 0 sporulation protein
LEPNOIND_00068 9.7e-183 holB 2.7.7.7 L DNA polymerase III
LEPNOIND_00069 1.1e-53 yaaQ S protein conserved in bacteria
LEPNOIND_00070 1.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEPNOIND_00071 4.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
LEPNOIND_00073 9.2e-186 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEPNOIND_00074 6e-277 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
LEPNOIND_00075 1.2e-199 adhA 1.1.1.1 C alcohol dehydrogenase
LEPNOIND_00076 6e-274 T Sigma-54 interaction domain
LEPNOIND_00077 1.7e-279 cckA 2.7.13.3 T GAF domain
LEPNOIND_00078 1.7e-12
LEPNOIND_00079 3.7e-210 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
LEPNOIND_00080 1.4e-34
LEPNOIND_00081 4e-144 pdaB 3.5.1.104 G Polysaccharide deacetylase
LEPNOIND_00082 4.1e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
LEPNOIND_00083 1.5e-58 gerD S Spore gernimation protein
LEPNOIND_00084 1.7e-102
LEPNOIND_00085 1.1e-175
LEPNOIND_00086 3.9e-101 S Sporulation delaying protein SdpA
LEPNOIND_00087 7.1e-77 S Bacterial PH domain
LEPNOIND_00088 4.1e-195 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LEPNOIND_00089 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEPNOIND_00090 1.7e-151 glcT K antiterminator
LEPNOIND_00091 8.9e-133 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEPNOIND_00092 1.4e-80 ybaK S Protein of unknown function (DUF2521)
LEPNOIND_00095 6.6e-14
LEPNOIND_00096 2.1e-115 S Rubrerythrin
LEPNOIND_00099 1.9e-30 yozG K Transcriptional regulator
LEPNOIND_00100 8.9e-82 S Protein of unknown function (DUF2975)
LEPNOIND_00101 1.7e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
LEPNOIND_00102 4.4e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEPNOIND_00103 1.1e-147 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEPNOIND_00104 1.2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEPNOIND_00105 6.9e-153 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEPNOIND_00106 8.4e-162 ecfA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEPNOIND_00107 9.4e-59 rplQ J Ribosomal protein L17
LEPNOIND_00108 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEPNOIND_00109 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEPNOIND_00110 1.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEPNOIND_00111 1.4e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LEPNOIND_00112 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEPNOIND_00113 1.4e-141 map 3.4.11.18 E Methionine aminopeptidase
LEPNOIND_00114 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEPNOIND_00115 2.2e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEPNOIND_00116 3.3e-74 rplO J binds to the 23S rRNA
LEPNOIND_00117 2.7e-25 rpmD J Ribosomal protein L30
LEPNOIND_00118 4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEPNOIND_00119 1.3e-60 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEPNOIND_00120 1.3e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEPNOIND_00121 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEPNOIND_00122 2.3e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEPNOIND_00123 6.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEPNOIND_00124 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEPNOIND_00125 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEPNOIND_00126 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
LEPNOIND_00127 4.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEPNOIND_00128 8.7e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEPNOIND_00129 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEPNOIND_00130 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEPNOIND_00131 1.7e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEPNOIND_00132 1.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEPNOIND_00133 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
LEPNOIND_00134 1.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEPNOIND_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LEPNOIND_00136 6.6e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEPNOIND_00137 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEPNOIND_00138 3.5e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEPNOIND_00139 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEPNOIND_00140 1e-35 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
LEPNOIND_00141 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEPNOIND_00142 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEPNOIND_00143 1.3e-122 rsmC 2.1.1.172 J Methyltransferase
LEPNOIND_00144 3.2e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEPNOIND_00145 3.5e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEPNOIND_00146 9.4e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEPNOIND_00147 6.3e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEPNOIND_00148 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
LEPNOIND_00149 6.1e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEPNOIND_00150 5.6e-118 sigH K Belongs to the sigma-70 factor family
LEPNOIND_00151 3e-87 yacP S RNA-binding protein containing a PIN domain
LEPNOIND_00152 4.9e-145 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEPNOIND_00153 5.1e-69 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEPNOIND_00154 2.5e-269 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEPNOIND_00155 2.5e-121 cysE 2.3.1.30 E Serine acetyltransferase
LEPNOIND_00156 1.8e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEPNOIND_00157 8.6e-84 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LEPNOIND_00158 7.6e-118 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LEPNOIND_00159 1.4e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
LEPNOIND_00160 2.7e-194 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LEPNOIND_00161 2.1e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEPNOIND_00162 0.0 clpC O Belongs to the ClpA ClpB family
LEPNOIND_00163 1.1e-195 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LEPNOIND_00164 2.3e-95 mcsA 2.7.14.1 S protein with conserved CXXC pairs
LEPNOIND_00165 1.5e-72 ctsR K Belongs to the CtsR family
LEPNOIND_00166 1.2e-85 2.3.1.128 J Acetyltransferase (GNAT) domain
LEPNOIND_00167 4.1e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
LEPNOIND_00168 1.2e-71 S Protein of unknown function (DUF2512)
LEPNOIND_00169 1.6e-66
LEPNOIND_00170 6e-114 panZ K Acetyltransferase (GNAT) domain
LEPNOIND_00171 2e-136 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEPNOIND_00172 1.2e-144 ydfC EG EamA-like transporter family
LEPNOIND_00173 1.7e-120 Q SAM-dependent methyltransferase
LEPNOIND_00174 1e-184 trpS 6.1.1.2 J Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LEPNOIND_00175 3.8e-145 Q ubiE/COQ5 methyltransferase family
LEPNOIND_00176 7.7e-91
LEPNOIND_00177 5e-90 2.3.1.128 J Acetyltransferase (GNAT) domain
LEPNOIND_00178 5.7e-205 P Oxidoreductase
LEPNOIND_00179 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LEPNOIND_00180 1.1e-57 cadC K transcriptional
LEPNOIND_00181 1.8e-144 aadD H KNTase C-terminal domain
LEPNOIND_00182 3.9e-63 blaI K Penicillinase repressor
LEPNOIND_00183 0.0 blaR 3.5.2.6 KTV BlaR1 peptidase M56
LEPNOIND_00184 4.3e-153 bla 3.5.2.6 V beta-lactamase
LEPNOIND_00185 1.1e-178 gluQ 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEPNOIND_00186 1.3e-97 S ABC-2 family transporter protein
LEPNOIND_00187 1.1e-161 V ABC transporter, ATP-binding protein
LEPNOIND_00188 4.1e-57 ytrA K GntR family transcriptional regulator
LEPNOIND_00189 2.5e-138 V ABC transporter
LEPNOIND_00190 0.0 V FtsX-like permease family
LEPNOIND_00191 1.2e-228 mefE EGP Transmembrane secretion effector
LEPNOIND_00192 4.8e-114 K Bacterial regulatory proteins, tetR family
LEPNOIND_00193 3.4e-194 T Histidine kinase-like ATPases
LEPNOIND_00194 1.7e-122 T Transcriptional regulatory protein, C terminal
LEPNOIND_00195 0.0 V FtsX-like permease family
LEPNOIND_00196 1.3e-142 V ABC transporter, ATP-binding protein
LEPNOIND_00197 4.3e-222 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LEPNOIND_00198 3.6e-73 K SpoVT / AbrB like domain
LEPNOIND_00199 8.6e-256 2.7.1.163 S Aminoglycoside phosphotransferase
LEPNOIND_00201 6.7e-173 E Proline dehydrogenase
LEPNOIND_00202 4.2e-155 ybfI K AraC-like ligand binding domain
LEPNOIND_00203 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEPNOIND_00205 1.6e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEPNOIND_00206 7.7e-222 ybbR S protein conserved in bacteria
LEPNOIND_00207 6.1e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEPNOIND_00208 1.9e-121 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LEPNOIND_00209 5.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
LEPNOIND_00214 1.5e-07
LEPNOIND_00216 3.4e-07
LEPNOIND_00219 1.9e-289 E COG0747 ABC-type dipeptide transport system, periplasmic component
LEPNOIND_00220 6.4e-105 E GDSL-like Lipase/Acylhydrolase
LEPNOIND_00221 1.3e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
LEPNOIND_00222 5.2e-77 rimL 2.3.1.128 J Acetyltransferase (GNAT) domain
LEPNOIND_00223 1.6e-71
LEPNOIND_00224 8.3e-24 K Helix-turn-helix domain
LEPNOIND_00225 2.6e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
LEPNOIND_00226 1e-48 padR K Transcriptional regulator PadR-like family
LEPNOIND_00227 2.7e-113 S Protein of unknown function (DUF2812)
LEPNOIND_00229 3.2e-134 KT Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding
LEPNOIND_00230 1.1e-190 MA20_01110 4.2.1.81 M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
LEPNOIND_00231 2.1e-165 K Acetyltransferase (GNAT) family
LEPNOIND_00232 6.1e-143 K MerR family transcriptional regulator
LEPNOIND_00233 1.2e-71
LEPNOIND_00234 1.1e-116 O Sap, sulfolipid-1-addressing protein
LEPNOIND_00235 3.8e-162 aacA-aphD 2.7.1.190 S Protein of unknown function (DUF1679)
LEPNOIND_00236 4.3e-141 K helix_turn_helix, mercury resistance
LEPNOIND_00237 2.3e-136 2.1.1.301 Q Methyltransferase domain
LEPNOIND_00238 1.7e-173 L Endonuclease/Exonuclease/phosphatase family
LEPNOIND_00241 2.3e-134 K DeoR C terminal sensor domain
LEPNOIND_00242 5.5e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_00243 1.9e-211 1.1.1.14 E Dehydrogenase
LEPNOIND_00244 7.2e-239 yoaB EGP Major facilitator Superfamily
LEPNOIND_00245 4.9e-56 S DUF35 OB-fold domain, acyl-CoA-associated
LEPNOIND_00246 6.1e-205 2.3.1.16, 2.3.1.9 I Thiolase, C-terminal domain
LEPNOIND_00247 1.5e-283 MA20_41335 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEPNOIND_00248 1.3e-92 S DNA-binding protein with PD1-like DNA-binding motif
LEPNOIND_00249 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
LEPNOIND_00250 1.1e-218 siaT_2 G Tripartite ATP-independent periplasmic transporter, DctM component
LEPNOIND_00251 2.2e-85 dctQ1 G Tripartite ATP-independent periplasmic transporters, DctQ component
LEPNOIND_00252 5.9e-191 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LEPNOIND_00253 9.2e-133 K Transcriptional regulator
LEPNOIND_00254 2.2e-204 S response regulator aspartate phosphatase
LEPNOIND_00256 2.8e-41 S Protein of unknown function (DUF2642)
LEPNOIND_00257 1.4e-175 cat P Catalase
LEPNOIND_00258 2.2e-170 aadK G Streptomycin adenylyltransferase
LEPNOIND_00259 2.7e-31 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
LEPNOIND_00260 1.4e-248 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
LEPNOIND_00261 3.1e-59 hxlR K HxlR-like helix-turn-helix
LEPNOIND_00262 8e-165 S Belongs to the pirin family
LEPNOIND_00263 1.3e-154 K Transcriptional regulator
LEPNOIND_00264 2.3e-207 S Protein of unknown function (DUF418)
LEPNOIND_00265 1.4e-30 S response regulator aspartate phosphatase
LEPNOIND_00266 1.3e-73
LEPNOIND_00268 1.3e-34
LEPNOIND_00269 2.8e-93 S Putative adhesin
LEPNOIND_00270 5.2e-122 S ABC-2 family transporter protein
LEPNOIND_00271 1.6e-166 V ABC transporter, ATP-binding protein
LEPNOIND_00272 1.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_00273 1.5e-192 T PhoQ Sensor
LEPNOIND_00274 5.8e-155 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEPNOIND_00275 4.5e-129 puuD 4.1.3.27 S Peptidase C26
LEPNOIND_00276 1.1e-203 S response regulator aspartate phosphatase
LEPNOIND_00277 8.6e-139 T helix_turn_helix, arabinose operon control protein
LEPNOIND_00278 9.5e-308 2.7.13.3 T Histidine kinase
LEPNOIND_00279 4.3e-292 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_00280 6.7e-201 fbpC2 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LEPNOIND_00281 6.5e-190 P Bacterial extracellular solute-binding protein
LEPNOIND_00283 3.9e-87
LEPNOIND_00284 2.7e-227 3.5.1.47 S Peptidase dimerisation domain
LEPNOIND_00285 1.9e-225 3.5.1.47 S Peptidase dimerisation domain
LEPNOIND_00286 2.9e-241 P Sodium:sulfate symporter transmembrane region
LEPNOIND_00287 1.5e-225 E Peptidase family M28
LEPNOIND_00288 5.2e-195 E Belongs to the ABC transporter superfamily
LEPNOIND_00289 5.5e-186 oppD P Belongs to the ABC transporter superfamily
LEPNOIND_00290 4.1e-167 EP N-terminal TM domain of oligopeptide transport permease C
LEPNOIND_00291 1e-157 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_00292 1.4e-292 E Bacterial extracellular solute-binding proteins, family 5 Middle
LEPNOIND_00294 5.6e-166 K Transcriptional regulator
LEPNOIND_00295 7.5e-161 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
LEPNOIND_00296 7.1e-211 ybhE S Bacterial protein of unknown function (DUF871)
LEPNOIND_00297 8.8e-51 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
LEPNOIND_00298 4.7e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
LEPNOIND_00299 6.5e-224 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPNOIND_00300 1.7e-45
LEPNOIND_00301 6.5e-251 celF 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEPNOIND_00302 1.1e-139 S CAAX protease self-immunity
LEPNOIND_00303 1.9e-86 S Bacterial PH domain
LEPNOIND_00304 1.2e-269 ydbT S Bacterial PH domain
LEPNOIND_00305 0.0 pbp1A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEPNOIND_00306 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEPNOIND_00307 2.5e-169 yppC S Protein of unknown function (DUF2515)
LEPNOIND_00309 9.2e-92 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LEPNOIND_00310 2.7e-61 yppE S Bacterial domain of unknown function (DUF1798)
LEPNOIND_00311 6e-15
LEPNOIND_00312 5.6e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LEPNOIND_00313 1.8e-98 pfpI 3.5.1.124 S DJ-1/PfpI family
LEPNOIND_00314 2.1e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEPNOIND_00315 2.8e-54 yusE CO cell redox homeostasis
LEPNOIND_00316 4.2e-77 yphP S Belongs to the UPF0403 family
LEPNOIND_00317 1.1e-74 CO Thioredoxin-like
LEPNOIND_00318 2.4e-138 T Calcineurin-like phosphoesterase superfamily domain
LEPNOIND_00319 8.8e-148 ypgR C COG0694 Thioredoxin-like proteins and domains
LEPNOIND_00320 5.5e-30
LEPNOIND_00321 2.1e-85 ydbS S Bacterial PH domain
LEPNOIND_00322 3.3e-259 ydbT S Membrane
LEPNOIND_00323 4.7e-193 S Protein of unknown function (DUF2777)
LEPNOIND_00324 3.4e-169
LEPNOIND_00325 7e-128 telA P Belongs to the TelA family
LEPNOIND_00326 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
LEPNOIND_00327 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LEPNOIND_00328 5e-113 ypjP S YpjP-like protein
LEPNOIND_00329 4.5e-39
LEPNOIND_00330 4e-65 kapB G Kinase associated protein B
LEPNOIND_00331 4.3e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEPNOIND_00333 3.6e-88
LEPNOIND_00334 3.2e-153 ycsE S hydrolases of the HAD superfamily
LEPNOIND_00335 1.3e-20
LEPNOIND_00336 1.4e-186 mhqA E COG0346 Lactoylglutathione lyase and related lyases
LEPNOIND_00337 8.4e-116 mhqD S Carboxylesterase
LEPNOIND_00338 4.4e-92
LEPNOIND_00339 3.4e-208 gerAC S Spore germination B3/ GerAC like, C-terminal
LEPNOIND_00340 1.2e-189 gerAB E Spore germination protein
LEPNOIND_00341 1.9e-259 gerAA EG Spore germination protein
LEPNOIND_00342 0.0 pepF E oligoendopeptidase F
LEPNOIND_00343 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LEPNOIND_00344 1.4e-228 yprB L RNase_H superfamily
LEPNOIND_00346 4.4e-95 ypsA S Belongs to the UPF0398 family
LEPNOIND_00347 7.7e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEPNOIND_00348 1.7e-69 rnhA 3.1.26.4 L An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
LEPNOIND_00349 1.4e-85 S Spore germination B3/ GerAC like, C-terminal
LEPNOIND_00350 1.4e-201 E Spore germination protein
LEPNOIND_00351 1.8e-273 P Spore gernimation protein GerA
LEPNOIND_00352 2.6e-67 S Src homology 3 domains
LEPNOIND_00353 1.8e-52
LEPNOIND_00354 5e-295 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Belongs to the FGGY kinase family
LEPNOIND_00355 7.8e-21 S Protein of unknown function (DUF2564)
LEPNOIND_00357 1.6e-219 G Transmembrane secretion effector
LEPNOIND_00358 2.5e-95 Q ubiE/COQ5 methyltransferase family
LEPNOIND_00359 4.3e-52 S Belongs to the HesB IscA family
LEPNOIND_00360 2.7e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LEPNOIND_00361 2.8e-100 IV02_12955 U MarC family integral membrane protein
LEPNOIND_00362 8.1e-148 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_00363 5.4e-192 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LEPNOIND_00364 1.4e-287 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
LEPNOIND_00365 7.8e-70 yccU S CoA-binding protein
LEPNOIND_00366 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEPNOIND_00367 1.5e-18 bofA S Sigma-K factor-processing regulatory protein BofA
LEPNOIND_00368 5.2e-31 S Protein of unknown function (DUF2508)
LEPNOIND_00369 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEPNOIND_00370 1.8e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEPNOIND_00371 1.2e-310 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEPNOIND_00372 6.2e-117 K Sigma-70, region 4
LEPNOIND_00373 4.8e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEPNOIND_00374 3.6e-85 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEPNOIND_00375 3e-09
LEPNOIND_00376 3e-298 gsiB_4 E COG0747 ABC-type dipeptide transport system, periplasmic component
LEPNOIND_00377 1.4e-159 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_00378 5.9e-169 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_00379 7.4e-194 oppD P Belongs to the ABC transporter superfamily
LEPNOIND_00380 2.6e-191 E Belongs to the ABC transporter superfamily
LEPNOIND_00381 2.7e-129 glnQ2 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEPNOIND_00382 1.9e-110 glnP E Polar amino acid ABC transporter, inner membrane subunit
LEPNOIND_00383 1.1e-144 glnH ET Ligated ion channel L-glutamate- and glycine-binding site
LEPNOIND_00384 1.2e-63 S Bacterial PH domain
LEPNOIND_00385 5.8e-269 gabD_2 1.2.1.9 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEPNOIND_00386 7.7e-194 hom2 1.1.1.3 E Homoserine dehydrogenase
LEPNOIND_00387 2.7e-227 amaA 3.5.1.47 E Peptidase dimerisation domain
LEPNOIND_00388 2.4e-228 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
LEPNOIND_00389 1.2e-235 eutD 3.4.13.9, 3.5.4.44 E Creatinase/Prolidase N-terminal domain
LEPNOIND_00390 5.4e-251 nhaC C Na H antiporter
LEPNOIND_00392 3.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
LEPNOIND_00393 2.2e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LEPNOIND_00394 0.0 QT COG2508 Regulator of polyketide synthase expression
LEPNOIND_00395 7.4e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LEPNOIND_00396 9.2e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEPNOIND_00397 1.5e-239 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LEPNOIND_00398 3.3e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LEPNOIND_00399 3.6e-150 yaaC S YaaC-like Protein
LEPNOIND_00401 1.8e-78 L Resolvase, N terminal domain
LEPNOIND_00402 7.7e-142 M lytic transglycosylase activity
LEPNOIND_00403 3.8e-63
LEPNOIND_00404 4.8e-187 M Psort location CytoplasmicMembrane, score
LEPNOIND_00405 2.3e-30
LEPNOIND_00406 0.0 yddE S AAA-like domain
LEPNOIND_00407 7.7e-57 D TcpE family
LEPNOIND_00408 2.4e-25 S Psort location CytoplasmicMembrane, score
LEPNOIND_00409 6e-79 S Conjugative transposon protein TcpC
LEPNOIND_00411 5.3e-32
LEPNOIND_00412 5.1e-27 K Transcriptional
LEPNOIND_00413 3.7e-133 S Replication-relaxation
LEPNOIND_00414 0.0 yukA S COG0433 Predicted ATPase
LEPNOIND_00415 2.8e-143 repE K Primase C terminal 1 (PriCT-1)
LEPNOIND_00416 3e-183 ftsA D cell division
LEPNOIND_00417 5.6e-24
LEPNOIND_00418 2.6e-47 S MerR HTH family regulatory protein
LEPNOIND_00419 1.5e-204 topB2 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEPNOIND_00421 5.8e-66
LEPNOIND_00423 3.2e-18
LEPNOIND_00424 2.6e-50 radC L RadC-like JAB domain
LEPNOIND_00430 7.9e-53 S YolD-like protein
LEPNOIND_00433 7e-44 nucH 3.1.31.1 L COG1525 Micrococcal nuclease (thermonuclease) homologs
LEPNOIND_00439 4e-232 S antiporter
LEPNOIND_00440 1.9e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEPNOIND_00441 6.1e-146 yihY S Belongs to the UPF0761 family
LEPNOIND_00442 1.1e-86 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEPNOIND_00443 3.1e-84 alaR K Transcriptional regulator
LEPNOIND_00444 3.9e-223 yugH 2.6.1.1 E Aminotransferase
LEPNOIND_00445 1.7e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LEPNOIND_00446 1.6e-205 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
LEPNOIND_00447 3.3e-52 J RNA binding protein (contains ribosomal protein S1 domain)
LEPNOIND_00448 1.2e-33 yuzA S Domain of unknown function (DUF378)
LEPNOIND_00449 3.1e-228 yugK C oxidoreductases, Fe-dependent alcohol dehydrogenase family
LEPNOIND_00450 8.3e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LEPNOIND_00451 3.5e-260 pgi 5.3.1.9 G Belongs to the GPI family
LEPNOIND_00452 2.5e-71 yugN S YugN-like family
LEPNOIND_00453 2.7e-21
LEPNOIND_00455 3.1e-07 yeaO S Protein of unknown function, DUF488
LEPNOIND_00456 3.8e-168 ppaC 3.6.1.1 C Inorganic pyrophosphatase
LEPNOIND_00457 8.7e-165 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LEPNOIND_00458 8.9e-84 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
LEPNOIND_00459 2.9e-58 S Protein of unknown function (DUF1516)
LEPNOIND_00460 2.6e-82 S DinB superfamily
LEPNOIND_00461 1.5e-77 S Putative small multi-drug export protein
LEPNOIND_00462 5.1e-238 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEPNOIND_00463 1.2e-106 pgpB3 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
LEPNOIND_00464 4.8e-163 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPNOIND_00465 1.4e-154 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPNOIND_00466 4.5e-149 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
LEPNOIND_00467 1e-176 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
LEPNOIND_00468 1.4e-124 catB 2.3.1.28 V This enzyme is an effector of chloramphenicol resistance in bacteria
LEPNOIND_00469 5.2e-72 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
LEPNOIND_00470 4e-36 K COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit
LEPNOIND_00471 5.6e-113 S Golgi phosphoprotein 3 (GPP34)
LEPNOIND_00472 1.7e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LEPNOIND_00473 5.8e-141 motA N flagellar motor
LEPNOIND_00474 2e-135 motB N Flagellar motor protein
LEPNOIND_00475 7.4e-203 ytvI S sporulation integral membrane protein YtvI
LEPNOIND_00476 9.1e-87 dksA T general stress protein
LEPNOIND_00477 4.1e-59 S Uncharacterized protein conserved in bacteria (DUF2200)
LEPNOIND_00478 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEPNOIND_00479 0.0 ypbR S Dynamin family
LEPNOIND_00480 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEPNOIND_00481 1.3e-128 dnaD L DNA replication protein DnaD
LEPNOIND_00482 3.4e-252 asnS 6.1.1.22 J asparaginyl-tRNA
LEPNOIND_00483 1.8e-84 ypmB S protein conserved in bacteria
LEPNOIND_00484 4.2e-22 ypmA S Protein of unknown function (DUF4264)
LEPNOIND_00485 7.8e-14
LEPNOIND_00486 1.9e-247 mtaD 3.5.4.28, 3.5.4.31 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
LEPNOIND_00487 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LEPNOIND_00488 6.2e-179 S Tetratricopeptide repeat
LEPNOIND_00489 2.7e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LEPNOIND_00490 3.5e-171 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LEPNOIND_00491 4.9e-151 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LEPNOIND_00492 3.5e-177 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEPNOIND_00493 1.8e-209 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEPNOIND_00494 8.7e-201 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
LEPNOIND_00495 5.7e-129 bshB1 S proteins, LmbE homologs
LEPNOIND_00496 7.9e-27
LEPNOIND_00497 1e-150 S Nucleotidyltransferase domain
LEPNOIND_00498 3.2e-166 ydhU P Catalase
LEPNOIND_00499 1.8e-193 3.5.1.28 M COG3103 SH3 domain protein
LEPNOIND_00500 8.1e-114 S CAAX protease self-immunity
LEPNOIND_00501 4.2e-127 mngR K UTRA
LEPNOIND_00502 2.2e-254 pagL 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEPNOIND_00503 7.7e-140 celG 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
LEPNOIND_00504 7.2e-256 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LEPNOIND_00506 4.5e-16
LEPNOIND_00507 4.8e-16
LEPNOIND_00508 2.3e-72 K helix_turn_helix multiple antibiotic resistance protein
LEPNOIND_00510 1.6e-118 glvR K Helix-turn-helix domain, rpiR family
LEPNOIND_00511 2.6e-258 4.3.2.2, 5.5.1.2 F Adenylosuccinate lyase C-terminus
LEPNOIND_00512 3e-287 malX 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEPNOIND_00513 5.8e-140 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LEPNOIND_00514 5.4e-62
LEPNOIND_00515 9.2e-98 S DinB superfamily
LEPNOIND_00516 2.6e-299 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
LEPNOIND_00517 7.5e-58
LEPNOIND_00518 6.1e-96
LEPNOIND_00519 1.8e-125
LEPNOIND_00520 1.5e-52 K Transcriptional regulator
LEPNOIND_00522 9.7e-39
LEPNOIND_00524 2.7e-58 S membrane
LEPNOIND_00525 7.5e-61 V HNH endonuclease
LEPNOIND_00526 6.6e-88 yokH G SMI1 / KNR4 family
LEPNOIND_00527 3.5e-07 S Protein of unknown function (DUF3006)
LEPNOIND_00528 1.3e-68 L Metallo-beta-lactamase superfamily
LEPNOIND_00530 3.4e-30
LEPNOIND_00531 3.5e-39 gepA S Protein of unknown function (DUF4065)
LEPNOIND_00532 6e-60
LEPNOIND_00534 3.9e-55 MV Ami_2
LEPNOIND_00535 1.1e-22 S Bacteriophage A118-like holin, Hol118
LEPNOIND_00536 6.2e-106 S response regulator aspartate phosphatase
LEPNOIND_00538 1.8e-196 UW nuclease activity
LEPNOIND_00540 2.6e-84 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEPNOIND_00541 3.6e-23 S Bacteriophage A118-like holin, Hol118
LEPNOIND_00542 4.6e-20 xhlA S Haemolysin XhlA
LEPNOIND_00543 2.7e-16
LEPNOIND_00544 4.8e-130 S outer membrane
LEPNOIND_00547 3.1e-42 S peptidoglycan catabolic process
LEPNOIND_00548 4.2e-31 S Phage tail protein
LEPNOIND_00549 8.1e-82 D Phage tail tape measure protein TP901
LEPNOIND_00550 9e-22 S Phage tail assembly chaperone protein, TAC
LEPNOIND_00551 2.2e-38 N domain, Protein
LEPNOIND_00552 9.1e-18 S Protein of unknown function (DUF3168)
LEPNOIND_00553 2.6e-28 S Bacteriophage HK97-gp10, putative tail-component
LEPNOIND_00554 4.2e-08
LEPNOIND_00555 2e-20 S Phage gp6-like head-tail connector protein
LEPNOIND_00557 1.3e-137 S Phage major capsid protein E
LEPNOIND_00558 2.1e-37
LEPNOIND_00559 7.9e-50 S Domain of unknown function (DUF4355)
LEPNOIND_00561 2.2e-59 S Phage Mu protein F like protein
LEPNOIND_00562 3.5e-146 S Phage portal protein, SPP1 Gp6-like
LEPNOIND_00563 8.7e-186 ps334 S Terminase-like family
LEPNOIND_00564 1.5e-75 xtmA L Terminase small subunit
LEPNOIND_00565 6.2e-99 S Protein of unknown function (DUF3800)
LEPNOIND_00566 2.5e-49
LEPNOIND_00567 9.7e-73 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
LEPNOIND_00568 3.3e-28 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LEPNOIND_00571 6e-15 S Phage-like element PBSX protein XtrA
LEPNOIND_00572 8.6e-41 K BRO family, N-terminal domain
LEPNOIND_00573 7.1e-115 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
LEPNOIND_00574 1.9e-39 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEPNOIND_00577 5.8e-55 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEPNOIND_00581 7.3e-41 xkdB K sequence-specific DNA binding
LEPNOIND_00583 1.2e-31
LEPNOIND_00587 7.1e-62
LEPNOIND_00588 1.7e-33 K sequence-specific DNA binding
LEPNOIND_00589 1.5e-11
LEPNOIND_00590 4.7e-53 KLT serine threonine protein kinase
LEPNOIND_00591 3e-42 E IrrE N-terminal-like domain
LEPNOIND_00592 3.1e-25
LEPNOIND_00593 1.5e-107 S recombinase activity
LEPNOIND_00595 1.1e-168 S membrane
LEPNOIND_00596 2.4e-242 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
LEPNOIND_00598 3.5e-70 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
LEPNOIND_00599 1.8e-115 mucD 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEPNOIND_00600 2e-61 yojF S Protein of unknown function (DUF1806)
LEPNOIND_00601 8.2e-125 bshB2 S deacetylase
LEPNOIND_00602 2.5e-169 polA 2.7.7.7 L Helix-hairpin-helix class 2 (Pol1 family) motifs
LEPNOIND_00603 5.8e-105 speG J Acetyltransferase (GNAT) domain
LEPNOIND_00604 1.6e-90 yocC
LEPNOIND_00605 6.4e-58 ytxJ O Protein of unknown function (DUF2847)
LEPNOIND_00606 0.0 recQ 3.6.4.12 L DNA helicase
LEPNOIND_00607 6.3e-159 S reductase
LEPNOIND_00608 4e-303 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEPNOIND_00609 5.4e-32 yozC
LEPNOIND_00610 5.2e-189 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LEPNOIND_00611 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LEPNOIND_00613 2.5e-208 2.1.1.163, 2.1.1.201 Q O-methyltransferase
LEPNOIND_00614 6.3e-119 M lytic transglycosylase activity
LEPNOIND_00616 3.6e-76 osmC O redox protein, regulator of disulfide bond formation
LEPNOIND_00617 0.0 topB1 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEPNOIND_00619 2.3e-173 V COG1131 ABC-type multidrug transport system, ATPase component
LEPNOIND_00620 1.6e-126 V ABC-2 type transporter
LEPNOIND_00621 1.6e-120 S ABC-2 type transporter
LEPNOIND_00622 6.1e-194 T Histidine kinase
LEPNOIND_00623 3.5e-106 KT LuxR family transcriptional regulator
LEPNOIND_00624 9.5e-12 KT LuxR family transcriptional regulator
LEPNOIND_00625 1.7e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LEPNOIND_00626 1e-125 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LEPNOIND_00627 2.8e-78 queD 4.1.2.50, 4.2.3.12 H synthase
LEPNOIND_00628 3.5e-128 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LEPNOIND_00629 1.5e-236 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LEPNOIND_00630 1.4e-251 agcS E Sodium alanine symporter
LEPNOIND_00631 7.2e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LEPNOIND_00632 2.5e-43 ywcE S Required for proper spore morphogenesis. Important for spore germination
LEPNOIND_00633 4.8e-51 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LEPNOIND_00634 4.7e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LEPNOIND_00635 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEPNOIND_00636 1.7e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LEPNOIND_00637 7.8e-44 S DNA alkylation repair protein
LEPNOIND_00638 4e-220 I COG0657 Esterase lipase
LEPNOIND_00639 1.5e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEPNOIND_00640 5.1e-53 yneR S Belongs to the HesB IscA family
LEPNOIND_00642 3.8e-162 cheV 2.7.13.3 T Chemotaxis protein CheV
LEPNOIND_00643 4.4e-177 3.4.13.19 E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
LEPNOIND_00644 3.9e-72 hspX O Belongs to the small heat shock protein (HSP20) family
LEPNOIND_00645 2.3e-29 S YppG-like protein
LEPNOIND_00646 7.9e-23
LEPNOIND_00647 6.1e-235 ykuI T Diguanylate phosphodiesterase
LEPNOIND_00648 3.6e-154 I Hydrolase
LEPNOIND_00649 7.9e-179 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LEPNOIND_00650 2e-80 S Domain of unknown function (DUF4352)
LEPNOIND_00651 1.5e-155 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEPNOIND_00652 1.7e-75 S thioesterase
LEPNOIND_00653 0.0 spoVK O stage V sporulation protein K
LEPNOIND_00654 5.6e-143 P Copper resistance protein D
LEPNOIND_00655 1.2e-11 sspN S Small acid-soluble spore protein N family
LEPNOIND_00657 7.9e-282 L COG3666 Transposase and inactivated derivatives
LEPNOIND_00658 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LEPNOIND_00660 4.9e-13
LEPNOIND_00661 3.9e-81 yneK S Protein of unknown function (DUF2621)
LEPNOIND_00662 0.0 mdlB V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEPNOIND_00663 0.0 mdlA V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEPNOIND_00664 7.9e-29 yneF S UPF0154 protein
LEPNOIND_00665 4.2e-74 yneE S Sporulation inhibitor of replication protein sirA
LEPNOIND_00666 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEPNOIND_00667 4.2e-34 ynzC S UPF0291 protein
LEPNOIND_00668 6.6e-119 yneB L resolvase
LEPNOIND_00670 2.6e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEPNOIND_00671 3.2e-220 yuxJ EGP Major facilitator Superfamily
LEPNOIND_00673 4.2e-214 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEPNOIND_00674 4e-98 MA20_21960 FG Domain of unknown function (DUF4269)
LEPNOIND_00675 6.7e-90
LEPNOIND_00676 1.2e-137 K helix_turn_helix isocitrate lyase regulation
LEPNOIND_00677 7.6e-143 Q Domain of unknown function (DUF2437)
LEPNOIND_00678 0.0 glcB 2.3.3.9 C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LEPNOIND_00679 1.1e-280 glcD 1.1.2.4, 1.1.3.15 C FAD linked oxidases, C-terminal domain
LEPNOIND_00680 2.3e-267 glcF C Glycolate oxidase
LEPNOIND_00681 4.5e-252 glcE C FAD binding domain
LEPNOIND_00682 1.3e-75 M Acetyltransferase (GNAT) domain
LEPNOIND_00683 2.1e-265 glnA 6.3.1.2 E glutamine synthetase
LEPNOIND_00684 9.6e-247 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LEPNOIND_00685 7.6e-169 spoVK O stage V sporulation protein K
LEPNOIND_00686 2.9e-190 xerD L Belongs to the 'phage' integrase family
LEPNOIND_00687 2.7e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LEPNOIND_00688 9.2e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEPNOIND_00689 4.2e-141 J Putative SAM-dependent methyltransferase
LEPNOIND_00690 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEPNOIND_00691 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEPNOIND_00692 2.6e-103 cotE S Spore coat protein
LEPNOIND_00693 8.9e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LEPNOIND_00694 4.7e-304 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LEPNOIND_00695 7e-155 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
LEPNOIND_00696 6.7e-38 spoVS S Stage V sporulation protein S
LEPNOIND_00697 3.4e-154 ymdB S protein conserved in bacteria
LEPNOIND_00698 1.8e-218 rny S Endoribonuclease that initiates mRNA decay
LEPNOIND_00699 4e-116 L DNA recombination
LEPNOIND_00701 8.7e-265 sbcC L AAA domain
LEPNOIND_00702 1.6e-188 L Calcineurin-like phosphoesterase superfamily domain
LEPNOIND_00703 2.3e-190 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEPNOIND_00704 1e-290 deaD 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEPNOIND_00705 5.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
LEPNOIND_00706 8.7e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEPNOIND_00707 2.1e-128 ymfM S protein conserved in bacteria
LEPNOIND_00708 4.6e-140 ymfK S Protein of unknown function (DUF3388)
LEPNOIND_00709 5.1e-40 ymfJ S Protein of unknown function (DUF3243)
LEPNOIND_00710 8.7e-125 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_00711 9.2e-250 ymfH S zinc protease
LEPNOIND_00712 3.6e-238 ymfF S Peptidase M16
LEPNOIND_00713 4.5e-129 ymfC K Transcriptional regulator
LEPNOIND_00714 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LEPNOIND_00715 1.9e-09 S YlzJ-like protein
LEPNOIND_00716 3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
LEPNOIND_00717 4.6e-311 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEPNOIND_00718 4.5e-163 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEPNOIND_00719 2.5e-220 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LEPNOIND_00720 1.2e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEPNOIND_00721 6.7e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LEPNOIND_00722 6.1e-160 spoVFA E subunit a
LEPNOIND_00723 3.3e-36 ymxH S YlmC YmxH family
LEPNOIND_00724 8.1e-227 pepR S Belongs to the peptidase M16 family
LEPNOIND_00725 9.8e-191 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
LEPNOIND_00726 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LEPNOIND_00727 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEPNOIND_00728 1e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LEPNOIND_00729 6.9e-175 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEPNOIND_00730 1.9e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEPNOIND_00731 2.3e-41 ylxP S protein conserved in bacteria
LEPNOIND_00732 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEPNOIND_00733 1.9e-47 ylxQ J ribosomal protein
LEPNOIND_00734 9.4e-43 ylxR K nucleic-acid-binding protein implicated in transcription termination
LEPNOIND_00735 5.2e-201 nusA K Participates in both transcription termination and antitermination
LEPNOIND_00736 5.6e-80 rimP S Required for maturation of 30S ribosomal subunits
LEPNOIND_00737 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEPNOIND_00738 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEPNOIND_00739 3.1e-234 rasP M zinc metalloprotease
LEPNOIND_00740 7e-209 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LEPNOIND_00741 1.6e-130 cdsA 2.7.7.41 S Belongs to the CDS family
LEPNOIND_00742 9.7e-146 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEPNOIND_00743 7.1e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEPNOIND_00744 7.4e-124 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LEPNOIND_00745 4.4e-150 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEPNOIND_00746 5.2e-133 rpsB J Belongs to the universal ribosomal protein uS2 family
LEPNOIND_00748 4.9e-134 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEPNOIND_00749 8.6e-84 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LEPNOIND_00750 8.3e-108 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LEPNOIND_00751 1.2e-171 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LEPNOIND_00752 1.1e-96
LEPNOIND_00753 3.1e-181 flhF N Flagellar biosynthesis regulator FlhF
LEPNOIND_00754 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEPNOIND_00755 1.6e-191 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEPNOIND_00756 1.1e-131 fliR N Flagellar biosynthetic protein FliR
LEPNOIND_00757 3.6e-39 fliQ N Role in flagellar biosynthesis
LEPNOIND_00758 2.8e-112 fliP N Plays a role in the flagellum-specific transport system
LEPNOIND_00759 4.6e-104 fliZ N Flagellar biosynthesis protein, FliO
LEPNOIND_00760 4.2e-59 cheY T cheY-homologous receiver domain
LEPNOIND_00761 5.4e-212 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LEPNOIND_00762 3.6e-177 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LEPNOIND_00763 6.3e-70 fliL N Controls the rotational direction of flagella during chemotaxis
LEPNOIND_00764 4.9e-28 flbD N protein, possibly involved in motility
LEPNOIND_00765 1.6e-146 flgG N Flagellar basal body rod
LEPNOIND_00766 6.2e-73 flgD N Flagellar basal body rod modification protein
LEPNOIND_00767 1.3e-269 N Flagellar hook-length control protein FliK
LEPNOIND_00769 8.2e-65 fliJ N bacterial-type flagellum organization
LEPNOIND_00770 6.8e-248 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LEPNOIND_00771 2.3e-78 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
LEPNOIND_00772 1.5e-175 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LEPNOIND_00773 3.4e-246 fliF N The M ring may be actively involved in energy transduction
LEPNOIND_00774 1.7e-42 fliE N Flagellar hook-basal body
LEPNOIND_00775 8.8e-75 flgC N Belongs to the flagella basal body rod proteins family
LEPNOIND_00776 1.7e-66 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LEPNOIND_00777 4.1e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LEPNOIND_00778 1.8e-227 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEPNOIND_00779 1.4e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEPNOIND_00780 4e-167 xerC L tyrosine recombinase XerC
LEPNOIND_00781 7.2e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LEPNOIND_00782 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEPNOIND_00783 5.6e-166 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
LEPNOIND_00784 9.7e-169 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LEPNOIND_00785 1.1e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LEPNOIND_00786 1.3e-79 ylqH S FlhB HrpN YscU SpaS Family
LEPNOIND_00787 3e-07 lig1
LEPNOIND_00788 8.3e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEPNOIND_00789 5.9e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEPNOIND_00790 1.2e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LEPNOIND_00792 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEPNOIND_00793 0.0 argS 6.1.1.19 J Arginyl tRNA synthetase N terminal dom
LEPNOIND_00794 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LEPNOIND_00795 4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEPNOIND_00796 9e-69 ylqD S YlqD protein
LEPNOIND_00797 2.5e-33 ylqC S Belongs to the UPF0109 family
LEPNOIND_00798 6.4e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LEPNOIND_00799 1.1e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEPNOIND_00800 2.3e-51 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEPNOIND_00801 2.6e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEPNOIND_00802 0.0 smc D Required for chromosome condensation and partitioning
LEPNOIND_00803 3.2e-09 yfkK S Belongs to the UPF0435 family
LEPNOIND_00804 4.4e-138 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEPNOIND_00805 5.4e-31 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEPNOIND_00806 2.3e-128 IQ reductase
LEPNOIND_00807 4.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LEPNOIND_00808 1.1e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEPNOIND_00809 1.3e-97 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LEPNOIND_00810 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEPNOIND_00811 7.7e-147 sdaAA 4.3.1.17 E L-serine dehydratase
LEPNOIND_00812 3.2e-121 sdaAB 4.3.1.17 E L-serine dehydratase
LEPNOIND_00813 8.5e-151 degV3 S protein conserved in bacteria
LEPNOIND_00814 2.8e-307 yloV S kinase related to dihydroxyacetone kinase
LEPNOIND_00815 2.5e-59 asp S protein conserved in bacteria
LEPNOIND_00816 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LEPNOIND_00818 2.7e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LEPNOIND_00819 7.4e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEPNOIND_00820 0.0 KLT serine threonine protein kinase
LEPNOIND_00821 9.1e-131 stp 3.1.3.16 T phosphatase
LEPNOIND_00822 2.2e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEPNOIND_00823 9.9e-169 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEPNOIND_00824 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEPNOIND_00825 1.9e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEPNOIND_00826 9.2e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEPNOIND_00827 3.7e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LEPNOIND_00828 3.5e-39 ylzA S Belongs to the UPF0296 family
LEPNOIND_00829 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
LEPNOIND_00830 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LEPNOIND_00831 0.0 yfhO S Bacterial membrane protein YfhO
LEPNOIND_00833 7.2e-121 Q ubiE/COQ5 methyltransferase family
LEPNOIND_00834 2.2e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEPNOIND_00835 1e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEPNOIND_00836 7.4e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEPNOIND_00837 1.5e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LEPNOIND_00838 0.0 carB 6.3.5.5 F Belongs to the CarB family
LEPNOIND_00839 3.8e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEPNOIND_00840 2.3e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEPNOIND_00841 1.1e-164 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LEPNOIND_00842 1.5e-231 pyrP F Xanthine uracil
LEPNOIND_00843 3.2e-104 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEPNOIND_00844 2.9e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEPNOIND_00845 1.8e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEPNOIND_00846 5.5e-115 dksA T COG1734 DnaK suppressor protein
LEPNOIND_00847 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEPNOIND_00848 4.8e-64 divIVA D Cell division initiation protein
LEPNOIND_00849 3e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
LEPNOIND_00850 2e-43 yggT S membrane
LEPNOIND_00851 3.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEPNOIND_00852 2e-118 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LEPNOIND_00853 7.7e-149 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
LEPNOIND_00854 9.8e-46 ylmC S sporulation protein
LEPNOIND_00855 2.1e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEPNOIND_00856 1.1e-124 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEPNOIND_00857 6.6e-162 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LEPNOIND_00858 1.1e-185 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEPNOIND_00859 1.3e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEPNOIND_00861 8.5e-126 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEPNOIND_00862 2.3e-185 spoVE D Belongs to the SEDS family
LEPNOIND_00863 1.1e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEPNOIND_00864 2.5e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEPNOIND_00865 2.6e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEPNOIND_00866 1e-273 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEPNOIND_00867 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
LEPNOIND_00868 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LEPNOIND_00869 2.3e-54 ftsL D cell division protein FtsL
LEPNOIND_00870 2.1e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEPNOIND_00871 2.6e-79 mraZ K Belongs to the MraZ family
LEPNOIND_00872 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LEPNOIND_00873 6.5e-10 S Protein of unknown function (DUF3397)
LEPNOIND_00874 1.7e-162 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEPNOIND_00875 3.6e-93 ylbP K n-acetyltransferase
LEPNOIND_00876 6.4e-67 S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LEPNOIND_00877 1.3e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LEPNOIND_00878 4.4e-94 yceD S metal-binding, possibly nucleic acid-binding protein
LEPNOIND_00879 1.4e-231 ylbM S Belongs to the UPF0348 family
LEPNOIND_00880 3.4e-194 ylbL T Belongs to the peptidase S16 family
LEPNOIND_00881 4e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
LEPNOIND_00882 8.5e-221 ylbJ S Sporulation integral membrane protein YlbJ
LEPNOIND_00883 7.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEPNOIND_00884 3.7e-99 rsmD 2.1.1.171 L Methyltransferase
LEPNOIND_00885 4.1e-65 S Methylthioribose kinase
LEPNOIND_00886 1.1e-46 ylbG S UPF0298 protein
LEPNOIND_00887 7.9e-60 ylbF S Belongs to the UPF0342 family
LEPNOIND_00888 1.3e-142 rimK1 HJ Prokaryotic glutathione synthetase, ATP-grasp domain
LEPNOIND_00889 1.2e-31 ylbE S YlbE-like protein
LEPNOIND_00890 3.5e-73 ylbD S Putative coat protein
LEPNOIND_00891 4.6e-85 yiiD Q protein, possibly involved in aromatic compounds catabolism
LEPNOIND_00892 9.5e-214 ylbC S protein with SCP PR1 domains
LEPNOIND_00893 9.5e-64 ylbA S YugN-like family
LEPNOIND_00894 4.6e-85
LEPNOIND_00895 3.9e-93 yozB S membrane
LEPNOIND_00896 1.1e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LEPNOIND_00897 9.7e-104 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LEPNOIND_00898 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEPNOIND_00899 1.1e-200 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LEPNOIND_00900 4.1e-159 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LEPNOIND_00901 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LEPNOIND_00902 9e-41 ylaN S Belongs to the UPF0358 family
LEPNOIND_00903 5.7e-94 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LEPNOIND_00904 2.7e-252 phoH T ATPase related to phosphate starvation-inducible protein PhoH
LEPNOIND_00905 3.2e-32 ylaI S protein conserved in bacteria
LEPNOIND_00906 7.2e-53 ylaH S YlaH-like protein
LEPNOIND_00907 0.0 typA T GTP-binding protein TypA
LEPNOIND_00908 3.8e-11 S Family of unknown function (DUF5325)
LEPNOIND_00909 1.1e-164 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LEPNOIND_00910 3.5e-154 suhB 3.1.3.25 G Inositol monophosphatase
LEPNOIND_00911 5.4e-118 yktB S Belongs to the UPF0637 family
LEPNOIND_00912 3.8e-41 yktA S Belongs to the UPF0223 family
LEPNOIND_00913 2e-280 speA 4.1.1.19 E Arginine
LEPNOIND_00914 4.8e-233 legA 3.5.1.2 O Peptidase family M48
LEPNOIND_00915 1.3e-132 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
LEPNOIND_00916 7.6e-281 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LEPNOIND_00917 1.5e-67 CO cell redox homeostasis
LEPNOIND_00918 4.2e-164 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_00919 1.4e-173 P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_00920 0.0 appA_2 E COG0747 ABC-type dipeptide transport system, periplasmic component
LEPNOIND_00921 5e-187 E Belongs to the ABC transporter superfamily
LEPNOIND_00922 1.8e-187 oppD P Belongs to the ABC transporter superfamily
LEPNOIND_00923 2.2e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEPNOIND_00924 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEPNOIND_00925 1.7e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEPNOIND_00926 3e-201 bkdA1 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEPNOIND_00927 1.1e-68 recN L Putative cell-wall binding lipoprotein
LEPNOIND_00928 5.3e-17 S Protein of unknown function (Tiny_TM_bacill)
LEPNOIND_00929 3e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEPNOIND_00930 2.4e-30 ykzG S Belongs to the UPF0356 family
LEPNOIND_00931 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEPNOIND_00932 5.8e-115 ktrA P COG0569 K transport systems, NAD-binding component
LEPNOIND_00933 9.1e-83 ykuV CO thiol-disulfide
LEPNOIND_00934 4.7e-102 ykuU O Alkyl hydroperoxide reductase
LEPNOIND_00935 7.8e-135 ykuT M Mechanosensitive ion channel
LEPNOIND_00936 2.4e-37 ykuS S Belongs to the UPF0180 family
LEPNOIND_00937 2.9e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEPNOIND_00938 7.1e-228 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
LEPNOIND_00939 7.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEPNOIND_00940 6e-147 S Membrane transport protein
LEPNOIND_00941 1.8e-192 T Metal dependent phosphohydrolases with conserved 'HD' motif.
LEPNOIND_00942 9.8e-200 yhdY M Mechanosensitive ion channel
LEPNOIND_00944 2.8e-97 copC S CopC domain
LEPNOIND_00945 2e-184 ytvI S AI-2E family transporter
LEPNOIND_00946 3.4e-112 GM NmrA-like family
LEPNOIND_00947 1.2e-225 E Peptidase family M28
LEPNOIND_00948 8.2e-193 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LEPNOIND_00950 1.4e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
LEPNOIND_00951 3.8e-28 copP P Heavy-metal-associated domain
LEPNOIND_00952 2e-46 csoR S transcriptional
LEPNOIND_00953 1e-30
LEPNOIND_00954 7.4e-146 ykrA S hydrolases of the HAD superfamily
LEPNOIND_00956 3.1e-59
LEPNOIND_00957 2.9e-75 yqiW S Belongs to the UPF0403 family
LEPNOIND_00958 6.7e-229 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEPNOIND_00959 5.7e-183 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEPNOIND_00960 1e-187 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEPNOIND_00961 8e-263 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEPNOIND_00962 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
LEPNOIND_00963 0.0 bkdR KT Transcriptional regulator
LEPNOIND_00964 9.4e-36 yqzF S Protein of unknown function (DUF2627)
LEPNOIND_00965 4.5e-119 2.7.8.33, 2.7.8.35 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEPNOIND_00966 7.1e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LEPNOIND_00967 2.2e-240 rseP 3.4.21.116 M Stage IV sporulation protein B
LEPNOIND_00968 3.8e-296 recN L May be involved in recombinational repair of damaged DNA
LEPNOIND_00969 4.6e-79 argR K Regulates arginine biosynthesis genes
LEPNOIND_00970 1.4e-150 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
LEPNOIND_00971 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEPNOIND_00972 3.3e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEPNOIND_00973 9.7e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEPNOIND_00974 1.5e-253 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEPNOIND_00975 1.1e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEPNOIND_00976 3.1e-66 yqhY S protein conserved in bacteria
LEPNOIND_00977 1.1e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LEPNOIND_00978 2.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEPNOIND_00979 1.1e-56
LEPNOIND_00980 1.2e-89 spoIIIAH S SpoIIIAH-like protein
LEPNOIND_00981 6.4e-114 spoIIIAG S stage III sporulation protein AG
LEPNOIND_00982 9.2e-96 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
LEPNOIND_00983 3.8e-205 spoIIIAE S stage III sporulation protein AE
LEPNOIND_00984 1.6e-40 spoIIIAD S Stage III sporulation protein AD
LEPNOIND_00985 4.4e-29 spoIIIAC S stage III sporulation protein AC
LEPNOIND_00986 1.1e-84 spoIIIAB S Stage III sporulation protein
LEPNOIND_00987 1.2e-169 spoIIIAA S stage III sporulation protein AA
LEPNOIND_00988 1.3e-35 yqhV S Protein of unknown function (DUF2619)
LEPNOIND_00989 1e-50 S YfzA-like protein
LEPNOIND_00990 1.1e-98 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LEPNOIND_00991 3.2e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEPNOIND_00992 2.4e-195 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LEPNOIND_00993 1.8e-89 yqhR S Conserved membrane protein YqhR
LEPNOIND_00994 2.7e-59
LEPNOIND_00995 3.6e-168 yqhO S esterase of the alpha-beta hydrolase superfamily
LEPNOIND_00996 1e-75 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LEPNOIND_00997 3.1e-200 splB 4.1.99.14 L Spore photoproduct lyase
LEPNOIND_00998 8.5e-159 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LEPNOIND_00999 0.0 helD 3.6.4.12 L DNA helicase
LEPNOIND_01000 9.5e-155 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LEPNOIND_01001 3.9e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
LEPNOIND_01002 6.3e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEPNOIND_01003 2.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEPNOIND_01004 4.1e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
LEPNOIND_01005 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEPNOIND_01006 3.8e-153 yqhG S Bacterial protein YqhG of unknown function
LEPNOIND_01007 6.6e-08 S Protein of unknown function (DUF2759)
LEPNOIND_01008 3e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LEPNOIND_01009 2e-36 yqgY S Protein of unknown function (DUF2626)
LEPNOIND_01012 1.4e-80
LEPNOIND_01014 1.5e-74 mshD NU general secretion pathway protein
LEPNOIND_01015 2.9e-48 comGC U Required for transformation and DNA binding
LEPNOIND_01016 1.2e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LEPNOIND_01024 6.7e-09
LEPNOIND_01026 5.6e-189 comGB NU COG1459 Type II secretory pathway, component PulF
LEPNOIND_01027 3e-187 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LEPNOIND_01028 0.0 yjcD 3.6.4.12 L DNA helicase
LEPNOIND_01029 7e-72
LEPNOIND_01030 2.1e-68 cotX S Spore Coat Protein X and V domain
LEPNOIND_01033 3.4e-137
LEPNOIND_01034 7.1e-127
LEPNOIND_01035 3e-144 Q ubiE/COQ5 methyltransferase family
LEPNOIND_01036 1.3e-60 yngL S Protein of unknown function (DUF1360)
LEPNOIND_01037 2e-138 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LEPNOIND_01038 9.2e-172 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEPNOIND_01039 6.8e-150 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEPNOIND_01040 2e-109 yjbM 2.7.6.5 S GTP pyrophosphokinase
LEPNOIND_01041 5.5e-62 yjbL S Belongs to the UPF0738 family
LEPNOIND_01042 4.2e-98 yjbK S protein conserved in bacteria
LEPNOIND_01043 1.3e-96 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LEPNOIND_01044 5.6e-73 yjbI S COG2346 Truncated hemoglobins
LEPNOIND_01045 1.9e-172 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LEPNOIND_01047 1.7e-237 yjbF S Competence protein
LEPNOIND_01048 2.1e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LEPNOIND_01049 1.3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEPNOIND_01051 9.1e-98 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEPNOIND_01052 2.9e-237 S Putative glycosyl hydrolase domain
LEPNOIND_01053 2.9e-13 yoeD G Helix-turn-helix domain
LEPNOIND_01054 3.5e-112 yplQ S protein, Hemolysin III
LEPNOIND_01055 2.1e-99 yueE S phosphohydrolase
LEPNOIND_01056 3.3e-106 stoA CO Redoxin
LEPNOIND_01058 1.5e-183 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LEPNOIND_01059 2.7e-10
LEPNOIND_01060 1.3e-142 yjbA S Belongs to the UPF0736 family
LEPNOIND_01061 4.9e-156 yjaZ O Zn-dependent protease
LEPNOIND_01062 8.1e-137 ywaC 2.7.6.5 S protein conserved in bacteria
LEPNOIND_01063 3.7e-179 coaA 2.7.1.33 F Pantothenic acid kinase
LEPNOIND_01064 2.3e-107 J protein with SCP PR1 domains
LEPNOIND_01065 9.2e-104 3.5.1.28 M Cell Wall Hydrolase
LEPNOIND_01067 0.0 cca 2.7.7.19, 2.7.7.72, 3.1.13.3, 3.1.3.7 J Poly A polymerase head domain
LEPNOIND_01068 0.0
LEPNOIND_01069 1.2e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEPNOIND_01070 1.7e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEPNOIND_01072 3e-13 comZ S ComZ
LEPNOIND_01073 1.1e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LEPNOIND_01074 1.9e-158 5.1.3.2 GM RmlD substrate binding domain
LEPNOIND_01075 3.3e-121 yjaU I carboxylic ester hydrolase activity
LEPNOIND_01076 1.5e-172 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LEPNOIND_01077 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
LEPNOIND_01078 1.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEPNOIND_01079 8.4e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LEPNOIND_01080 2.2e-134 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LEPNOIND_01081 2.1e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LEPNOIND_01082 2.7e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LEPNOIND_01083 7.4e-166 ctaG S cytochrome c oxidase
LEPNOIND_01084 9.5e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LEPNOIND_01085 1.8e-78 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) domain
LEPNOIND_01086 2.2e-108
LEPNOIND_01087 9.2e-231 ywqB S zinc ion binding
LEPNOIND_01088 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEPNOIND_01090 1.9e-30 ipi S Intracellular proteinase inhibitor
LEPNOIND_01091 2.8e-146 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
LEPNOIND_01092 5.6e-149 yjfP S COG1073 Hydrolases of the alpha beta superfamily
LEPNOIND_01093 2.3e-41
LEPNOIND_01094 9.9e-64 ytwF P Sulfurtransferase
LEPNOIND_01095 7.5e-92
LEPNOIND_01096 7.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LEPNOIND_01097 1.5e-155 ykgA E Amidinotransferase
LEPNOIND_01099 2.2e-70 yxxG
LEPNOIND_01100 1.7e-91 wapA M COG3209 Rhs family protein
LEPNOIND_01102 0.0 wapA M COG3209 Rhs family protein
LEPNOIND_01103 2.3e-47 S IDEAL
LEPNOIND_01104 0.0 asnB 6.3.5.4 E Asparagine synthase
LEPNOIND_01105 8e-73 cheW NT chemotaxis
LEPNOIND_01106 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
LEPNOIND_01107 0.0 recB 3.1.11.5, 3.1.12.1, 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LEPNOIND_01108 0.0 addB 3.6.4.12 L exonuclease activity
LEPNOIND_01109 7.1e-62
LEPNOIND_01110 6.5e-111 phoU P Plays a role in the regulation of phosphate uptake
LEPNOIND_01111 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEPNOIND_01112 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEPNOIND_01113 9.4e-161 pstA P Phosphate transport system permease
LEPNOIND_01114 6.4e-160 pstC P probably responsible for the translocation of the substrate across the membrane
LEPNOIND_01115 7.4e-169 pstS P Phosphate
LEPNOIND_01116 2.1e-82 S DinB family
LEPNOIND_01117 8e-274 nylA 3.5.1.4 J Belongs to the amidase family
LEPNOIND_01118 5.1e-133 S Peptidase C26
LEPNOIND_01119 1.9e-214 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
LEPNOIND_01120 1.1e-118 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
LEPNOIND_01122 1.2e-213 Q COG1228 Imidazolonepropionase and related amidohydrolases
LEPNOIND_01123 4e-44 abrB K SpoVT / AbrB like domain
LEPNOIND_01124 1.7e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LEPNOIND_01125 1.8e-56 ysxB J ribosomal protein
LEPNOIND_01126 2.2e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
LEPNOIND_01127 2.2e-271 rng J ribonuclease, Rne Rng family
LEPNOIND_01128 1.2e-152 spoIVFB S Stage IV sporulation protein
LEPNOIND_01129 7e-130 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
LEPNOIND_01130 1e-170 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
LEPNOIND_01131 6.3e-94 bioY S BioY family
LEPNOIND_01132 1.3e-73 moaC 4.6.1.17 H MoaC family
LEPNOIND_01133 2e-92 yfkM 3.5.1.124 S protease
LEPNOIND_01134 1.6e-140 minD D Belongs to the ParA family
LEPNOIND_01135 2.3e-122 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LEPNOIND_01136 8.8e-74 mreD M shape-determining protein
LEPNOIND_01137 2.1e-160 mreC M Involved in formation and maintenance of cell shape
LEPNOIND_01138 8.9e-187 mreB D Rod shape-determining protein MreB
LEPNOIND_01139 4.4e-121 radC E Belongs to the UPF0758 family
LEPNOIND_01140 2.4e-104 maf D septum formation protein Maf
LEPNOIND_01141 0.0 yuxL 3.4.19.1 EU peptidase
LEPNOIND_01142 9.1e-198
LEPNOIND_01143 7.7e-121 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LEPNOIND_01144 3.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LEPNOIND_01145 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEPNOIND_01146 4.9e-31
LEPNOIND_01147 4.3e-106
LEPNOIND_01148 1.5e-191 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LEPNOIND_01149 1.2e-165
LEPNOIND_01150 2.2e-162 spoVID M stage VI sporulation protein D
LEPNOIND_01151 1.1e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LEPNOIND_01152 3.7e-182 hemB 4.2.1.24 H Belongs to the ALAD family
LEPNOIND_01153 8.6e-139 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LEPNOIND_01154 3.4e-169 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LEPNOIND_01155 2.4e-147 hemX O cytochrome C
LEPNOIND_01156 1.4e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LEPNOIND_01157 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
LEPNOIND_01158 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LEPNOIND_01159 5.1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
LEPNOIND_01160 1e-237 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEPNOIND_01161 3.9e-232 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEPNOIND_01162 4.5e-180 trxA2 O COG0457 FOG TPR repeat
LEPNOIND_01163 9.2e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEPNOIND_01164 6.1e-271 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEPNOIND_01165 5.3e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LEPNOIND_01166 1.4e-284 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LEPNOIND_01167 1.2e-178 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LEPNOIND_01168 1.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
LEPNOIND_01169 0.0 ilvB 2.2.1.6 E Acetolactate synthase
LEPNOIND_01170 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LEPNOIND_01171 3.1e-74
LEPNOIND_01172 8.1e-274 M Glycosyl transferase family group 2
LEPNOIND_01173 3.3e-307 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
LEPNOIND_01176 9.4e-97 ysnB S Phosphoesterase
LEPNOIND_01177 1.6e-108 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEPNOIND_01178 8e-137 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LEPNOIND_01179 7.7e-184 gerM S COG5401 Spore germination protein
LEPNOIND_01180 1.7e-195 yceA S Belongs to the UPF0176 family
LEPNOIND_01181 2.5e-23 C 4Fe-4S binding domain
LEPNOIND_01182 2.4e-150 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LEPNOIND_01183 1.9e-80 ysmB 2.4.2.28 K transcriptional
LEPNOIND_01184 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEPNOIND_01185 1.3e-38 ptsH G phosphocarrier protein HPr
LEPNOIND_01186 1.6e-32 gerE K Transcriptional regulator
LEPNOIND_01187 2.5e-80 fcbC S thioesterase
LEPNOIND_01188 9.5e-146 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LEPNOIND_01189 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LEPNOIND_01190 2.7e-111 sdhC C succinate dehydrogenase
LEPNOIND_01191 7.2e-229 ktrB P COG0168 Trk-type K transport systems, membrane components
LEPNOIND_01192 1.3e-75 yslB S Protein of unknown function (DUF2507)
LEPNOIND_01193 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEPNOIND_01194 1.8e-53 trxA O Belongs to the thioredoxin family
LEPNOIND_01195 1.1e-175 etfA C Electron transfer flavoprotein
LEPNOIND_01196 1.1e-133 etfB C Electron transfer flavoprotein
LEPNOIND_01197 4.4e-138 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LEPNOIND_01198 4.6e-103 fadR K Transcriptional regulator
LEPNOIND_01199 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEPNOIND_01200 2.4e-66 yshE S membrane
LEPNOIND_01201 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEPNOIND_01202 0.0 polX L COG1796 DNA polymerase IV (family X)
LEPNOIND_01203 6e-86 cvpA S membrane protein, required for colicin V production
LEPNOIND_01204 3.1e-34 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LEPNOIND_01205 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEPNOIND_01206 2e-194 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEPNOIND_01207 5.7e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEPNOIND_01208 1.4e-30 sspI S Belongs to the SspI family
LEPNOIND_01210 2.1e-16
LEPNOIND_01211 9.8e-205 ysdC G COG1363 Cellulase M and related proteins
LEPNOIND_01212 1.3e-64 ysdB S Sigma-w pathway protein YsdB
LEPNOIND_01213 1.7e-263 actP S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEPNOIND_01214 5.5e-53 S Protein of unknown function, DUF485
LEPNOIND_01215 2.3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEPNOIND_01216 4.4e-29 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LEPNOIND_01217 4.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEPNOIND_01218 2.3e-210 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
LEPNOIND_01219 1.2e-118 macB V ABC transporter, ATP-binding protein
LEPNOIND_01220 4.9e-238 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEPNOIND_01221 8.6e-123
LEPNOIND_01222 1.2e-274 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
LEPNOIND_01223 1e-178 strT C Aldo/keto reductase family
LEPNOIND_01224 5e-187 S Oxidoreductase family, NAD-binding Rossmann fold
LEPNOIND_01225 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEPNOIND_01226 6.2e-162 ytxC S YtxC-like family
LEPNOIND_01227 4.2e-225 mqnC 1.21.98.1, 2.5.1.120, 2.5.1.77 H Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)
LEPNOIND_01228 1.7e-173 dnaI L Primosomal protein DnaI
LEPNOIND_01229 7.9e-250 dnaB L Membrane attachment protein
LEPNOIND_01230 1.8e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEPNOIND_01231 3e-66
LEPNOIND_01232 1.4e-68 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LEPNOIND_01233 6.8e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEPNOIND_01234 5.4e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEPNOIND_01235 1.4e-105 ytaF P Probably functions as a manganese efflux pump
LEPNOIND_01236 9.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEPNOIND_01237 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEPNOIND_01238 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
LEPNOIND_01239 4.4e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_01240 8.9e-75 lrpC K helix_turn_helix ASNC type
LEPNOIND_01241 8.2e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
LEPNOIND_01242 2.6e-241 icd 1.1.1.42 C isocitrate
LEPNOIND_01243 5.2e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
LEPNOIND_01244 6.7e-73 yeaL S UPF0756 membrane protein
LEPNOIND_01245 1.4e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
LEPNOIND_01246 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LEPNOIND_01247 9.8e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEPNOIND_01248 1.2e-180 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LEPNOIND_01249 1.1e-153 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEPNOIND_01250 9e-116 lutR_1 K helix_turn_helix gluconate operon transcriptional repressor
LEPNOIND_01251 1.2e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
LEPNOIND_01252 0.0 dnaE 2.7.7.7 L DNA polymerase
LEPNOIND_01253 7.2e-53 ytrH S Sporulation protein YtrH
LEPNOIND_01254 4.2e-89 ytrI
LEPNOIND_01255 8.6e-173 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
LEPNOIND_01256 4.6e-08 ytpI S YtpI-like protein
LEPNOIND_01257 6.7e-240 ytoI K transcriptional regulator containing CBS domains
LEPNOIND_01259 5.6e-129 ytkL S Belongs to the UPF0173 family
LEPNOIND_01260 8e-210 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LEPNOIND_01261 5.4e-65
LEPNOIND_01262 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_01264 1.8e-259 argH 4.3.2.1 E argininosuccinate lyase
LEPNOIND_01265 4.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LEPNOIND_01266 2.2e-12 S EcsC protein family
LEPNOIND_01267 8.1e-171 yhaM S 3'-5' exoribonuclease yhaM
LEPNOIND_01268 2.3e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEPNOIND_01269 1.4e-181 ytxK 2.1.1.72 L DNA methylase
LEPNOIND_01270 2.7e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEPNOIND_01271 2.4e-196 ywoG EGP Major facilitator Superfamily
LEPNOIND_01272 8.4e-75 ytfJ S Sporulation protein YtfJ
LEPNOIND_01273 5.4e-124 ytfI S Protein of unknown function (DUF2953)
LEPNOIND_01274 1.7e-99 yteJ S RDD family
LEPNOIND_01275 3.5e-180 sppA OU signal peptide peptidase SppA
LEPNOIND_01276 8.1e-28 sspB S spore protein
LEPNOIND_01277 1.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEPNOIND_01278 5.3e-209 iscS2 2.8.1.7 E Cysteine desulfurase
LEPNOIND_01279 1.3e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEPNOIND_01280 1.6e-148 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LEPNOIND_01281 3.6e-114 yttP K Transcriptional regulator
LEPNOIND_01282 2.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
LEPNOIND_01283 1.3e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEPNOIND_01284 1.1e-234 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEPNOIND_01285 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M COG0744 Membrane carboxypeptidase (penicillin-binding protein)
LEPNOIND_01286 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LEPNOIND_01287 8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LEPNOIND_01288 4e-116 acuB S Acetoin utilization protein AcuB
LEPNOIND_01289 1.2e-238 acuC BQ histone deacetylase
LEPNOIND_01290 2.3e-185 ccpA K catabolite control protein A
LEPNOIND_01291 4.1e-198 aroA 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LEPNOIND_01292 3.9e-16 XK27_07760 S COG4980 Gas vesicle protein
LEPNOIND_01293 4.3e-63 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEPNOIND_01294 6.9e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LEPNOIND_01295 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
LEPNOIND_01296 7.7e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEPNOIND_01297 5.3e-147 ytpQ S Belongs to the UPF0354 family
LEPNOIND_01298 1e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LEPNOIND_01299 3.8e-118 S Phosphotransferase system, EIIC
LEPNOIND_01300 1.9e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
LEPNOIND_01301 3.5e-91 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LEPNOIND_01302 3.6e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LEPNOIND_01303 5.7e-49 ytzB
LEPNOIND_01304 6.9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEPNOIND_01305 6.3e-14 S YtzH-like protein
LEPNOIND_01306 7.6e-154 ytmP 2.7.1.89 M Phosphotransferase
LEPNOIND_01307 8.8e-164 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LEPNOIND_01308 5.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_01309 1.5e-52 S PFAM Uncharacterised protein family UPF0150
LEPNOIND_01310 6.6e-213 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEPNOIND_01311 9.9e-194 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEPNOIND_01312 1.4e-178 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEPNOIND_01313 5.2e-219 1.8.1.4 C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEPNOIND_01314 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
LEPNOIND_01315 7.3e-100 lrgB M effector of murein hydrolase
LEPNOIND_01316 2.9e-64 cidA S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LEPNOIND_01317 1.5e-108 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LEPNOIND_01318 3.3e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LEPNOIND_01319 4.3e-166 ydeE K AraC family transcriptional regulator
LEPNOIND_01320 4.3e-49 K helix_turn_helix, mercury resistance
LEPNOIND_01321 4.3e-152 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPNOIND_01322 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LEPNOIND_01323 1.5e-30 ytzE K COG1349 Transcriptional regulators of sugar metabolism
LEPNOIND_01324 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEPNOIND_01325 6.9e-212 rodA D Belongs to the SEDS family
LEPNOIND_01326 9.5e-198 ftsW D Belongs to the SEDS family
LEPNOIND_01327 1.5e-286 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEPNOIND_01328 1e-167 yvrE G SMP-30/Gluconolaconase/LRE-like region
LEPNOIND_01329 4.1e-71 yugU S Uncharacterised protein family UPF0047
LEPNOIND_01330 8.2e-229 yhaA1 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LEPNOIND_01331 3e-208 ytfP S HI0933-like protein
LEPNOIND_01332 7.2e-66
LEPNOIND_01333 6.1e-77 S An automated process has identified a potential problem with this gene model
LEPNOIND_01334 4.8e-132 S Protein of unknown function (DUF3100)
LEPNOIND_01335 1.6e-241 3.5.1.47 S amidohydrolase
LEPNOIND_01336 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEPNOIND_01337 1.3e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LEPNOIND_01338 8.1e-192 yttB EGP Major facilitator Superfamily
LEPNOIND_01340 3.5e-103 ytqB J Putative rRNA methylase
LEPNOIND_01341 2.6e-106 4.2.1.1 P Reversible hydration of carbon dioxide
LEPNOIND_01342 1.7e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
LEPNOIND_01343 2e-68 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LEPNOIND_01344 6.1e-227 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEPNOIND_01345 6.6e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LEPNOIND_01346 8.3e-153 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LEPNOIND_01347 7e-181 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LEPNOIND_01348 2.1e-137 ytlC P ABC transporter
LEPNOIND_01349 5.9e-138 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEPNOIND_01350 5.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
LEPNOIND_01351 3.7e-224 ymfD EGP Major facilitator Superfamily
LEPNOIND_01352 7.9e-85 ywpF S YwpF-like protein
LEPNOIND_01354 1.3e-223 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LEPNOIND_01355 1.1e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
LEPNOIND_01356 8.2e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
LEPNOIND_01357 1.8e-107 mrr V Restriction endonuclease
LEPNOIND_01358 5.8e-82 L Transposase IS200 like
LEPNOIND_01360 1.7e-07
LEPNOIND_01362 2.7e-45
LEPNOIND_01363 3.6e-282 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LEPNOIND_01364 7e-79 yuiD S protein conserved in bacteria
LEPNOIND_01365 2.5e-112 yuiC S protein conserved in bacteria
LEPNOIND_01366 1.5e-47 yuiB S Putative membrane protein
LEPNOIND_01367 4.4e-230 yumB 1.6.99.3 C NADH dehydrogenase
LEPNOIND_01368 2.1e-185 ycgT 1.18.1.2, 1.19.1.1 C reductase
LEPNOIND_01369 1.7e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
LEPNOIND_01370 3e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LEPNOIND_01371 0.0 mtlR K transcriptional regulator, MtlR
LEPNOIND_01372 1.5e-308 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
LEPNOIND_01373 1.6e-154 yckB ET Belongs to the bacterial solute-binding protein 3 family
LEPNOIND_01374 3.3e-110 yecS P COG0765 ABC-type amino acid transport system, permease component
LEPNOIND_01375 2.9e-60 erpA S Belongs to the HesB IscA family
LEPNOIND_01376 7.6e-09 S Spo0E like sporulation regulatory protein
LEPNOIND_01377 6.7e-209 mqnE 1.21.98.1, 2.5.1.120, 2.5.1.77 H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LEPNOIND_01378 8.7e-164 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEPNOIND_01379 1.4e-42
LEPNOIND_01380 7.6e-41 yuzB S Belongs to the UPF0349 family
LEPNOIND_01381 0.0 yutJ 1.6.99.3 C NADH dehydrogenase
LEPNOIND_01382 1.7e-51 yuzD S protein conserved in bacteria
LEPNOIND_01383 9.7e-36 yutI O COG0694 Thioredoxin-like proteins and domains
LEPNOIND_01384 7e-164 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEPNOIND_01385 8.9e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LEPNOIND_01386 1.8e-237 hom 1.1.1.3 E homoserine dehydrogenase
LEPNOIND_01387 7.5e-210 yutH S Spore coat protein
LEPNOIND_01388 4.6e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LEPNOIND_01389 1.2e-135 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEPNOIND_01390 1.9e-77 yutE S Protein of unknown function DUF86
LEPNOIND_01391 6e-44
LEPNOIND_01392 3.7e-50 yutD S protein conserved in bacteria
LEPNOIND_01393 1e-93 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEPNOIND_01394 1.6e-174 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LEPNOIND_01395 5.5e-205 lytH M Peptidase, M23
LEPNOIND_01396 3.4e-295 nhaC C Na+/H+ antiporter family
LEPNOIND_01397 4.6e-140 yunB S Sporulation protein YunB (Spo_YunB)
LEPNOIND_01398 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEPNOIND_01399 1.5e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEPNOIND_01400 1.2e-49 yunC S Domain of unknown function (DUF1805)
LEPNOIND_01401 1.1e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LEPNOIND_01402 1e-140 yunE S membrane transporter protein
LEPNOIND_01403 1.7e-167 yunF S Protein of unknown function DUF72
LEPNOIND_01404 1.2e-64 S Domain of unknown function (DUF5082)
LEPNOIND_01405 7.2e-48
LEPNOIND_01406 3.6e-148
LEPNOIND_01407 1.6e-46
LEPNOIND_01408 4.6e-232 S LXG domain of WXG superfamily
LEPNOIND_01409 4e-41 S Family of unknown function (DUF5344)
LEPNOIND_01410 3.4e-168 kka S Phosphotransferase enzyme family
LEPNOIND_01411 1.1e-181 P Periplasmic binding protein
LEPNOIND_01412 9.3e-147 K AraC family transcriptional regulator
LEPNOIND_01413 3.5e-188 gpr C Aldo/keto reductase family
LEPNOIND_01414 6.4e-139 bioC_2 Q Methyltransferase domain
LEPNOIND_01415 5.9e-41 3.2.1.86 GT1 G beta-glucosidase activity
LEPNOIND_01416 1e-51 licT K transcriptional antiterminator
LEPNOIND_01417 5.8e-17 S YhfH-like protein
LEPNOIND_01418 3.5e-241 aceA 4.1.3.1 C Isocitrate lyase
LEPNOIND_01419 7.4e-269 sufB O FeS cluster assembly
LEPNOIND_01420 5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
LEPNOIND_01421 6.5e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEPNOIND_01422 1.2e-244 O assembly protein SufD
LEPNOIND_01423 7.1e-144 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LEPNOIND_01424 6.4e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEPNOIND_01425 1.5e-169 btuF P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LEPNOIND_01426 8.5e-96 S Cobalamin adenosyltransferase
LEPNOIND_01427 9.7e-155 metQ P Belongs to the NlpA lipoprotein family
LEPNOIND_01428 2e-115 metI P COG2011 ABC-type metal ion transport system, permease component
LEPNOIND_01429 2e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEPNOIND_01430 1.2e-64 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LEPNOIND_01431 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
LEPNOIND_01432 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
LEPNOIND_01433 1.7e-213 fadA 2.3.1.16 I Belongs to the thiolase family
LEPNOIND_01434 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
LEPNOIND_01435 1.2e-225 EGP Major facilitator Superfamily
LEPNOIND_01436 0.0 S Sugar transport-related sRNA regulator N-term
LEPNOIND_01437 4.6e-128 S Glycosyltransferase like family
LEPNOIND_01438 5.7e-139 3.5.1.104 G Polysaccharide deacetylase
LEPNOIND_01440 6.4e-108 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LEPNOIND_01441 2.4e-250 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEPNOIND_01442 2.6e-250 S protein conserved in bacteria
LEPNOIND_01443 5.6e-64 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEPNOIND_01445 5.1e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LEPNOIND_01446 7.1e-60 mhqP S DoxX
LEPNOIND_01447 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEPNOIND_01448 3.5e-140 est 3.1.1.1 S Carboxylesterase
LEPNOIND_01449 3.8e-138 S COG1647 Esterase lipase
LEPNOIND_01450 1.6e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEPNOIND_01451 7.1e-28 secG U Preprotein translocase subunit SecG
LEPNOIND_01452 1.2e-79 yclD
LEPNOIND_01453 4e-265 S Tripartite tricarboxylate transporter TctA family
LEPNOIND_01454 1.3e-76 S Tripartite tricarboxylate transporter TctB family
LEPNOIND_01455 5.8e-164 S Tripartite tricarboxylate transporter family receptor
LEPNOIND_01456 4.6e-224 4.2.1.158 M Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
LEPNOIND_01457 3.8e-268 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEPNOIND_01458 8.8e-170 dapAf2 4.3.3.7 EM Dihydrodipicolinate synthetase family
LEPNOIND_01459 5.4e-119 MA20_15070 K FCD
LEPNOIND_01460 3.3e-239 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEPNOIND_01461 5.2e-300 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
LEPNOIND_01462 2.2e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEPNOIND_01463 4.1e-220 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LEPNOIND_01464 1e-187 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEPNOIND_01465 4.2e-181 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LEPNOIND_01466 6.9e-206 S response regulator aspartate phosphatase
LEPNOIND_01468 2.3e-40 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LEPNOIND_01469 1e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LEPNOIND_01470 7e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEPNOIND_01471 6.6e-234 E Peptidase dimerisation domain
LEPNOIND_01472 1.5e-56 S Domain of unknown function (DUF4870)
LEPNOIND_01473 5.4e-217 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LEPNOIND_01474 8.7e-108 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LEPNOIND_01475 3.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEPNOIND_01476 8.7e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LEPNOIND_01477 5e-38 crh G Phosphocarrier protein Chr
LEPNOIND_01478 4.3e-178 whiA K May be required for sporulation
LEPNOIND_01479 1.9e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LEPNOIND_01480 5.2e-167 rapZ S Displays ATPase and GTPase activities
LEPNOIND_01481 5.7e-91 yvcI 3.6.1.55 F Nudix hydrolase
LEPNOIND_01482 5.9e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEPNOIND_01483 3e-198 S COG0457 FOG TPR repeat
LEPNOIND_01484 5.3e-242 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
LEPNOIND_01485 1.5e-146 yobR 2.3.1.1 K FR47-like protein
LEPNOIND_01486 3.3e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
LEPNOIND_01487 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LEPNOIND_01488 2.7e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LEPNOIND_01489 2.2e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LEPNOIND_01490 4.2e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LEPNOIND_01491 6.2e-230 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LEPNOIND_01492 2.1e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LEPNOIND_01493 3.5e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LEPNOIND_01494 4.7e-74 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
LEPNOIND_01495 1.6e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LEPNOIND_01496 4.5e-161 yvoD P COG0370 Fe2 transport system protein B
LEPNOIND_01497 2.1e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEPNOIND_01498 1.8e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEPNOIND_01499 2.4e-48 yvlD S Membrane
LEPNOIND_01501 1.9e-152 yvlB S Putative adhesin
LEPNOIND_01502 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEPNOIND_01503 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEPNOIND_01504 2.9e-171 yoaV3 EG EamA-like transporter family
LEPNOIND_01505 5.7e-206 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEPNOIND_01506 1.4e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
LEPNOIND_01507 2.6e-101 D peptidase
LEPNOIND_01508 2.7e-152 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LEPNOIND_01509 1.4e-124 ftsE D cell division ATP-binding protein FtsE
LEPNOIND_01510 2.5e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
LEPNOIND_01511 5.1e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEPNOIND_01512 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEPNOIND_01513 7.1e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEPNOIND_01514 2.9e-30 cspB K cold-shock protein
LEPNOIND_01515 2.6e-152
LEPNOIND_01517 1.3e-66 fliS N flagellar protein FliS
LEPNOIND_01518 0.0 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LEPNOIND_01519 1.2e-49 flaG N flagellar protein FlaG
LEPNOIND_01520 1.2e-33 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LEPNOIND_01521 1.1e-77 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LEPNOIND_01522 3.2e-192 flgL N Belongs to the bacterial flagellin family
LEPNOIND_01523 5.5e-297 flgK N flagellar hook-associated protein
LEPNOIND_01525 1.2e-39 N Anti-sigma-28 factor, FlgM
LEPNOIND_01526 4.5e-76 yvyF S flagellar protein
LEPNOIND_01527 2.6e-129 comFC S Phosphoribosyl transferase domain
LEPNOIND_01528 2.3e-187 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LEPNOIND_01529 7.6e-152 degV S protein conserved in bacteria
LEPNOIND_01530 2.1e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEPNOIND_01531 4.1e-201 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LEPNOIND_01532 6.6e-116 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
LEPNOIND_01533 6.2e-108 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LEPNOIND_01534 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
LEPNOIND_01535 4e-151 oppC EP binding-protein-dependent transport systems inner membrane component
LEPNOIND_01536 1.5e-175 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_01537 3.7e-147 oppF P Belongs to the ABC transporter superfamily
LEPNOIND_01538 2e-194 oppD P Belongs to the ABC transporter superfamily
LEPNOIND_01539 1.4e-80 asnC K helix_turn_helix ASNC type
LEPNOIND_01540 1.4e-187 ywtF K Transcriptional regulator
LEPNOIND_01541 9.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEPNOIND_01542 4.4e-291 M Glycosyltransferase like family 2
LEPNOIND_01543 0.0 tagF 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEPNOIND_01544 9e-71 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
LEPNOIND_01545 6.1e-137 2.7.8.34 I CDP-alcohol phosphatidyltransferase
LEPNOIND_01546 5.4e-236 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LEPNOIND_01547 1.8e-251 wcaJ M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LEPNOIND_01548 2.7e-199 exoA M Glycosyltransferase like family 2
LEPNOIND_01549 3.3e-138 E lipolytic protein G-D-S-L family
LEPNOIND_01550 4.2e-65 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LEPNOIND_01551 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEPNOIND_01552 1.2e-191 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEPNOIND_01553 3e-113 ymaB S MutT family
LEPNOIND_01554 3e-101 pncA Q COG1335 Amidases related to nicotinamidase
LEPNOIND_01555 1.2e-26
LEPNOIND_01556 1.1e-218 yaaH M Glycoside Hydrolase Family
LEPNOIND_01557 5.8e-135 IQ Enoyl-(Acyl carrier protein) reductase
LEPNOIND_01558 2.4e-302 cscA 3.2.1.26, 3.2.1.80 GH32 G invertase
LEPNOIND_01559 0.0 sacC 3.2.1.26, 3.2.1.80 GH32 G invertase
LEPNOIND_01560 0.0 lplA5 G Bacterial extracellular solute-binding protein
LEPNOIND_01561 5e-162 lplC7 G COG0395 ABC-type sugar transport system, permease component
LEPNOIND_01562 1.1e-175 lplB7 G COG4209 ABC-type polysaccharide transport system, permease component
LEPNOIND_01564 2e-183 scrR K transcriptional
LEPNOIND_01566 1.3e-114
LEPNOIND_01567 5.3e-206 msmX E ABC transporter
LEPNOIND_01568 1.3e-157 araQ P Binding-protein-dependent transport system inner membrane component
LEPNOIND_01569 8.4e-165 araP G Binding-protein-dependent transport system inner membrane component
LEPNOIND_01570 6.2e-257 G Bacterial extracellular solute-binding protein
LEPNOIND_01571 3.4e-299 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
LEPNOIND_01572 1.6e-52 K sequence-specific DNA binding
LEPNOIND_01573 1.3e-159 S NYN domain
LEPNOIND_01574 1.7e-135
LEPNOIND_01576 8.6e-63 K helix_turn_helix gluconate operon transcriptional repressor
LEPNOIND_01577 2.1e-123 yhcG V ABC transporter, ATP-binding protein
LEPNOIND_01578 2.9e-140
LEPNOIND_01579 5.4e-10
LEPNOIND_01580 2.1e-109 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
LEPNOIND_01581 2.3e-141 3.1.26.11 S Metallo-beta-lactamase superfamily
LEPNOIND_01582 5.7e-86 K Transcriptional regulator
LEPNOIND_01583 4.1e-118 KLT serine threonine protein kinase
LEPNOIND_01584 1.1e-11 KLT serine threonine protein kinase
LEPNOIND_01585 1.9e-39
LEPNOIND_01586 1.6e-210 yhcY 2.7.13.3 T Histidine kinase
LEPNOIND_01587 2.1e-117 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEPNOIND_01589 6.4e-190 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEPNOIND_01590 2.6e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPNOIND_01591 3.3e-103 S Bacteriocin-protection, YdeI or OmpD-Associated
LEPNOIND_01592 1.4e-167 K WYL domain
LEPNOIND_01593 9.9e-91 S DinB family
LEPNOIND_01594 1.3e-153 yidA S hydrolases of the HAD superfamily
LEPNOIND_01595 1.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEPNOIND_01596 2.9e-212 S Oxidoreductase family, NAD-binding Rossmann fold
LEPNOIND_01597 7.4e-177 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LEPNOIND_01598 4e-110 adaA 3.2.2.21 K Transcriptional regulator
LEPNOIND_01599 1.5e-92 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEPNOIND_01600 3e-40
LEPNOIND_01614 6.2e-193 UW nuclease activity
LEPNOIND_01617 1.1e-17
LEPNOIND_01620 1e-176 S Oxidoreductase family, NAD-binding Rossmann fold
LEPNOIND_01621 2e-173 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LEPNOIND_01622 2.7e-140 tuaG GT2 M Glycosyltransferase like family 2
LEPNOIND_01623 7.8e-70
LEPNOIND_01624 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEPNOIND_01625 2.5e-248 M -O-antigen
LEPNOIND_01626 1.2e-55
LEPNOIND_01627 1.8e-201 M Glycosyl transferases group 1
LEPNOIND_01628 1.2e-151 exoM S Glycosyl transferase family 2
LEPNOIND_01629 6.7e-257 S Polysaccharide biosynthesis protein
LEPNOIND_01630 1.2e-117 sufR K Transcriptional regulator
LEPNOIND_01631 5.5e-115 sodA 1.15.1.1 P Iron/manganese superoxide dismutases, C-terminal domain
LEPNOIND_01632 5.7e-39 S Protein of unknown function (DUF1450)
LEPNOIND_01633 2.5e-23 C 4Fe-4S binding domain
LEPNOIND_01634 9.4e-247 3.5.1.47 S Peptidase dimerisation domain
LEPNOIND_01635 1.3e-279 abgT H AbgT putative transporter family
LEPNOIND_01636 4.2e-275 abgB 3.5.1.47 S amidohydrolase
LEPNOIND_01637 1.1e-242 KT transcriptional regulatory protein
LEPNOIND_01638 3.9e-142 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
LEPNOIND_01639 4.2e-214 MA20_04465 4.2.3.1 E Pyridoxal-phosphate dependent enzyme
LEPNOIND_01640 4e-80 M PFAM secretion protein HlyD family protein
LEPNOIND_01641 1.7e-142 V COG1131 ABC-type multidrug transport system, ATPase component
LEPNOIND_01642 3e-199 V COG0842 ABC-type multidrug transport system, permease component
LEPNOIND_01643 4.9e-117 K Transcriptional regulator
LEPNOIND_01644 1.8e-72 fabH 2.3.1.180 I Chalcone and stilbene synthases, N-terminal domain
LEPNOIND_01645 1.7e-104 ywqN S NAD(P)H-dependent
LEPNOIND_01646 2.4e-161 K LysR substrate binding domain
LEPNOIND_01650 4.7e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
LEPNOIND_01651 5.8e-72
LEPNOIND_01652 3.6e-157 kbaY 4.1.2.13, 4.1.2.40 G in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
LEPNOIND_01653 1.8e-75 fruD 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEPNOIND_01654 1.8e-230 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
LEPNOIND_01655 7.3e-172 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
LEPNOIND_01656 3.3e-141 rpl K Helix-turn-helix domain, rpiR family
LEPNOIND_01657 1.3e-165 T Belongs to the universal stress protein A family
LEPNOIND_01659 1.6e-51
LEPNOIND_01660 2.4e-56
LEPNOIND_01661 7.3e-197 potD2 E COG0687 Spermidine putrescine-binding periplasmic protein
LEPNOIND_01662 4.1e-175 iunH3 3.2.2.1 F nucleoside hydrolase
LEPNOIND_01663 2.1e-138 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
LEPNOIND_01664 7.4e-133 potC3 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_01665 1.3e-196 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LEPNOIND_01666 0.0 ade 3.5.4.2 F Adenine deaminase C-terminal domain
LEPNOIND_01667 1.9e-308 M1-554 G Endonuclease Exonuclease Phosphatase
LEPNOIND_01668 4.1e-13 S Inner spore coat protein D
LEPNOIND_01669 3.3e-61 Z012_01525 FJ tRNA wobble adenosine to inosine editing
LEPNOIND_01670 1.4e-156 P PFAM binding-protein-dependent transport systems inner membrane component
LEPNOIND_01671 1.1e-161 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_01672 3.1e-242 G ABC transporter substrate-binding protein
LEPNOIND_01673 5.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEPNOIND_01674 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LEPNOIND_01675 6.8e-136 lacR K DeoR C terminal sensor domain
LEPNOIND_01676 9.4e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEPNOIND_01677 8e-293 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LEPNOIND_01678 8.4e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LEPNOIND_01679 4.4e-275 mdr EGP Major facilitator Superfamily
LEPNOIND_01680 0.0 rocB E arginine degradation protein
LEPNOIND_01681 9.4e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
LEPNOIND_01682 2.5e-49
LEPNOIND_01683 7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_01684 1.5e-194 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
LEPNOIND_01685 3.9e-142 yvcR V ABC transporter, ATP-binding protein
LEPNOIND_01686 0.0 V ABC transporter (permease)
LEPNOIND_01688 0.0 copA 3.6.3.54 P P-type ATPase
LEPNOIND_01689 4.7e-160 S CAAX amino terminal protease family protein
LEPNOIND_01690 5.6e-172 K Putative sugar-binding domain
LEPNOIND_01691 4.9e-60 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
LEPNOIND_01692 1.2e-183 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
LEPNOIND_01693 5.6e-89 srlA G PTS system enzyme II sorbitol-specific factor
LEPNOIND_01694 9.8e-68 K Glucitol operon activator protein (GutM)
LEPNOIND_01695 9.6e-236 thrA E SAF
LEPNOIND_01696 8.3e-38 ptsH G PTS HPr component phosphorylation site
LEPNOIND_01697 8.6e-125
LEPNOIND_01698 1.3e-94 S VanZ like family
LEPNOIND_01699 4.6e-79 yybA 2.3.1.57 K transcriptional
LEPNOIND_01700 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEPNOIND_01701 1.1e-175 ssuA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LEPNOIND_01702 1.2e-103 ssuC P Binding-protein-dependent transport system inner membrane component
LEPNOIND_01703 2.3e-156 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LEPNOIND_01704 5.2e-256 glcF C Glycolate oxidase
LEPNOIND_01705 5.3e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
LEPNOIND_01706 1.1e-206 ysfB KT regulator
LEPNOIND_01707 1.2e-233 yxiO S COG2270 Permeases of the major facilitator superfamily
LEPNOIND_01708 1.2e-141 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LEPNOIND_01709 3.3e-155 S Tetratricopeptide repeat
LEPNOIND_01710 5.6e-183 manA 5.3.1.8 G mannose-6-phosphate isomerase
LEPNOIND_01712 9.7e-302 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LEPNOIND_01713 2.8e-88
LEPNOIND_01714 5e-10 K Transcriptional regulator
LEPNOIND_01715 9.4e-127 S KR domain
LEPNOIND_01716 5.5e-57 S Family of unknown function (DUF5367)
LEPNOIND_01717 8.3e-105 K Bacterial regulatory proteins, tetR family
LEPNOIND_01718 2.9e-165 EG EamA-like transporter family
LEPNOIND_01719 8.7e-254 ywoF P Right handed beta helix region
LEPNOIND_01720 1.5e-97 mutT 3.6.1.13, 3.6.1.55 L nUDIX hydrolase
LEPNOIND_01721 2.4e-19
LEPNOIND_01722 3.9e-62 S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEPNOIND_01723 6.9e-114 M Peptidase family M23
LEPNOIND_01725 1.6e-257 G Bacterial extracellular solute-binding protein
LEPNOIND_01726 4.6e-149 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_01727 1.6e-163 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_01728 5.2e-217 3.2.1.180 GH88 O Glycosyl Hydrolase Family 88
LEPNOIND_01729 4.5e-171 3.2.2.21 K AraC-like ligand binding domain
LEPNOIND_01730 4.7e-229 S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_01731 1.1e-211 S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_01732 2.8e-101 3.2.2.21 K AraC-like ligand binding domain
LEPNOIND_01733 8.9e-144 G Xylose isomerase-like TIM barrel
LEPNOIND_01734 7.3e-155 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_01735 2.8e-171 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_01736 5.6e-255 G Bacterial extracellular solute-binding protein
LEPNOIND_01737 1.2e-210 S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_01738 2e-140 G Xylose isomerase-like TIM barrel
LEPNOIND_01739 7.2e-172 3.2.2.21 K Cupin domain
LEPNOIND_01740 7.6e-191 S Oxidoreductase family, NAD-binding Rossmann fold
LEPNOIND_01741 3.1e-65 S Protein of unknown function, DUF393
LEPNOIND_01742 1.8e-151 yfhB 5.3.3.17 S PhzF family
LEPNOIND_01743 9.9e-106 V Beta-lactamase
LEPNOIND_01744 4.4e-92 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEPNOIND_01745 2.2e-311 2.6.1.52 E Aminotransferase class-V
LEPNOIND_01746 0.0 ltaS 2.7.8.20 M Sulfatase
LEPNOIND_01747 2.9e-69 E lactoylglutathione lyase activity
LEPNOIND_01748 1.8e-156 3.5.1.28 M COG3103 SH3 domain protein
LEPNOIND_01750 1.5e-166 yjfC O Predicted Zn-dependent protease (DUF2268)
LEPNOIND_01751 2.5e-156 htpX O Belongs to the peptidase M48B family
LEPNOIND_01752 2.9e-26 mcbG S Pentapeptide repeats (9 copies)
LEPNOIND_01753 4.9e-148 araQ P PFAM binding-protein-dependent transport systems inner membrane component
LEPNOIND_01754 3.9e-162 lacF G Binding-protein-dependent transport system inner membrane component
LEPNOIND_01755 3.1e-245 araN G ABC transporter substrate-binding protein
LEPNOIND_01756 1.1e-50 S Branched-chain amino acid transport protein (AzlD)
LEPNOIND_01757 6.3e-120 azlC E AzlC protein
LEPNOIND_01758 8.6e-99 ydcN K Helix-turn-helix XRE-family like proteins
LEPNOIND_01759 7.7e-91 M FR47-like protein
LEPNOIND_01760 2.5e-142 rrmA 2.1.1.187 Q Methyltransferase domain
LEPNOIND_01762 1e-35 S membrane
LEPNOIND_01763 7.2e-95 S Peptidase M50
LEPNOIND_01764 4.1e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
LEPNOIND_01765 4.2e-118 ypgQ S phosphohydrolase
LEPNOIND_01766 1.4e-27
LEPNOIND_01767 2.1e-288 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
LEPNOIND_01768 1.4e-206 S Protein of unknown function (DUF917)
LEPNOIND_01769 6e-217 codB_1 F cytosine purines uracil thiamine allantoin
LEPNOIND_01770 1.1e-104 K Bacterial regulatory proteins, tetR family
LEPNOIND_01771 7.6e-144 K acetyltransferase
LEPNOIND_01772 1.2e-80 S Stage II sporulation protein P (SpoIIP)
LEPNOIND_01773 5.5e-166 KLT Protein kinase domain
LEPNOIND_01774 1.2e-57 FG HIT domain
LEPNOIND_01775 1.1e-183 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEPNOIND_01776 4.8e-99 S Histidine kinase
LEPNOIND_01777 5.9e-94
LEPNOIND_01779 1.6e-182 S COG1073 Hydrolases of the alpha beta superfamily
LEPNOIND_01780 3.2e-237 S protein conserved in bacteria
LEPNOIND_01781 3.4e-255 3.5.4.28, 3.5.4.31 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
LEPNOIND_01782 1.1e-220 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LEPNOIND_01783 6.2e-249 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
LEPNOIND_01784 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LEPNOIND_01785 2.8e-282 T COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
LEPNOIND_01786 4e-221 G Transmembrane secretion effector
LEPNOIND_01787 7.2e-195 desK 2.7.13.3 T Histidine kinase
LEPNOIND_01788 1.1e-104 K helix_turn_helix, Lux Regulon
LEPNOIND_01789 4.2e-118
LEPNOIND_01790 1.6e-154 licT K antiterminator
LEPNOIND_01791 3.5e-269 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LEPNOIND_01792 3.7e-176 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LEPNOIND_01793 1.5e-87 M Protein of unknown function (DUF1541)
LEPNOIND_01794 7.3e-71
LEPNOIND_01795 2.8e-296 expZ S ABC transporter
LEPNOIND_01796 5.1e-209 gatD 1.1.1.14 C Alcohol dehydrogenase GroES-like domain
LEPNOIND_01797 7.3e-21
LEPNOIND_01798 7.5e-194 gutB 1.1.1.1, 1.1.1.14 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEPNOIND_01799 9.4e-215 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
LEPNOIND_01800 1.3e-42 gatB_1 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
LEPNOIND_01801 4e-81 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEPNOIND_01802 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
LEPNOIND_01803 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LEPNOIND_01804 2.1e-199
LEPNOIND_01805 7.7e-109 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
LEPNOIND_01806 5e-176 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
LEPNOIND_01807 4.6e-107 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LEPNOIND_01808 5.6e-95 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
LEPNOIND_01809 3e-200 MA20_17100 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
LEPNOIND_01810 1.6e-85 G Tripartite ATP-independent periplasmic transporters, DctQ component
LEPNOIND_01811 1.3e-182 dctP_1 G Bacterial extracellular solute-binding protein, family 7
LEPNOIND_01812 2.9e-182 kdgR K transcriptional
LEPNOIND_01813 1.5e-52 K Transcriptional regulator PadR-like family
LEPNOIND_01814 1.1e-74
LEPNOIND_01815 6.2e-76
LEPNOIND_01816 1.2e-199 frvX 3.2.1.4 GH5,GH9 G M42 glutamyl aminopeptidase
LEPNOIND_01817 3.9e-44 S Membrane
LEPNOIND_01818 3.4e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
LEPNOIND_01819 9.1e-166 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LEPNOIND_01820 5e-145 tagG GM Transport permease protein
LEPNOIND_01821 6.9e-147 S GNAT acetyltransferase
LEPNOIND_01822 0.0 3.6.3.8 P COG0474 Cation transport ATPase
LEPNOIND_01823 1.2e-296 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LEPNOIND_01824 1.4e-24
LEPNOIND_01825 2.1e-306 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
LEPNOIND_01826 3.1e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
LEPNOIND_01827 5.1e-111 modB P COG4149 ABC-type molybdate transport system, permease component
LEPNOIND_01828 2.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEPNOIND_01829 1.8e-190 vraS 2.7.13.3 T Histidine kinase
LEPNOIND_01830 5.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
LEPNOIND_01831 1.4e-105
LEPNOIND_01833 1.9e-30
LEPNOIND_01834 9.7e-117 4.4.1.3, 5.3.1.15 S Cupin
LEPNOIND_01835 0.0 DSE4 M glycoside hydrolase family 81
LEPNOIND_01836 4.4e-194 purR11 K helix_turn _helix lactose operon repressor
LEPNOIND_01837 4.1e-127 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
LEPNOIND_01838 1.3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEPNOIND_01839 1.7e-173 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_01840 1.7e-179 K WYL domain
LEPNOIND_01841 1.8e-113 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LEPNOIND_01842 3.9e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEPNOIND_01843 7.8e-150 czcD P COG1230 Co Zn Cd efflux system component
LEPNOIND_01844 5.7e-49 czrA K transcriptional
LEPNOIND_01845 1.7e-165 gltC K Transcriptional regulator
LEPNOIND_01846 3.2e-264 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
LEPNOIND_01847 8.8e-139 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEPNOIND_01848 3.5e-177 P ABC transporter substrate-binding protein
LEPNOIND_01849 3.2e-203 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
LEPNOIND_01850 1.4e-139 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
LEPNOIND_01851 2.2e-57 S Dinitrogenase iron-molybdenum cofactor
LEPNOIND_01852 1.4e-245 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEPNOIND_01853 1.5e-92 ssuE 1.5.1.38 S FMN reductase
LEPNOIND_01854 2.7e-163 ytlI K LysR substrate binding domain
LEPNOIND_01855 1.4e-86 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LEPNOIND_01856 1.2e-115 S membrane
LEPNOIND_01857 1.8e-27 sspB S spore protein
LEPNOIND_01858 1.3e-28 sspB S spore protein
LEPNOIND_01859 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEPNOIND_01861 3.6e-157 acrR_2 K Transcriptional regulator
LEPNOIND_01862 2.9e-128
LEPNOIND_01863 5.3e-164 V ATPases associated with a variety of cellular activities
LEPNOIND_01864 1.3e-60 gntR1 K helix_turn_helix gluconate operon transcriptional repressor
LEPNOIND_01865 3.9e-113 Q Methyltransferase domain
LEPNOIND_01866 2.1e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LEPNOIND_01868 1e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEPNOIND_01869 3.1e-169 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
LEPNOIND_01870 3.4e-174 P Catalase
LEPNOIND_01871 2.5e-261 S Predicted membrane protein (DUF2254)
LEPNOIND_01872 4.8e-162 opuAC E Glycine betaine ABC transporter
LEPNOIND_01873 1.1e-242 yhdP S COG1253 Hemolysins and related proteins containing CBS domains
LEPNOIND_01874 2e-143 srtB 3.4.22.70 S Sortase family
LEPNOIND_01875 1.8e-136 fhuC 3.6.3.28, 3.6.3.34 HP ABC transporter, ATP-binding protein
LEPNOIND_01876 2.2e-171 fhuB11 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPNOIND_01877 1.2e-163 isdE P ABC transporter substrate-binding protein
LEPNOIND_01878 0.0 M Cell surface protein
LEPNOIND_01879 1.8e-111 isdC M NEAr Transporter domain
LEPNOIND_01880 8.1e-54 isdG 1.14.99.48, 1.14.99.57 C Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
LEPNOIND_01881 2.1e-172 fhuG 3.6.3.34 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPNOIND_01882 7.4e-172 fhuD P Periplasmic binding protein
LEPNOIND_01883 2.2e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEPNOIND_01884 8.1e-148 2.1.1.144, 2.1.1.197 S Methyltransferase domain
LEPNOIND_01885 2.2e-111 K Bacterial transcriptional repressor C-terminal
LEPNOIND_01886 3e-249 EGP Major facilitator Superfamily
LEPNOIND_01887 2.3e-229 EGP Major facilitator Superfamily
LEPNOIND_01888 8.9e-123 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LEPNOIND_01889 1.2e-154 K LysR substrate binding domain
LEPNOIND_01890 9.9e-182 S Alpha/beta hydrolase family
LEPNOIND_01891 1.7e-156 5.1.3.22, 5.3.1.5 G Xylose isomerase-like TIM barrel
LEPNOIND_01892 2.8e-185 S Oxidoreductase family, NAD-binding Rossmann fold
LEPNOIND_01893 7.2e-189 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_01894 2.1e-146 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_01895 4.1e-170 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_01896 1.1e-242 cycB_2 G Bacterial extracellular solute-binding protein
LEPNOIND_01897 1e-226 GK ROK family
LEPNOIND_01898 1e-221 P Protein of unknown function (DUF418)
LEPNOIND_01899 2.6e-66 S YolD-like protein
LEPNOIND_01902 5.6e-294 K Mga helix-turn-helix domain
LEPNOIND_01903 4e-47
LEPNOIND_01904 1e-81 cwlM 3.5.1.28 M COG3103 SH3 domain protein
LEPNOIND_01905 0.0 clpE O Belongs to the ClpA ClpB family
LEPNOIND_01906 0.0 pepF E oligoendopeptidase
LEPNOIND_01907 4.6e-200 sstT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEPNOIND_01908 1e-268
LEPNOIND_01909 2.9e-171 yjlA EG Putative multidrug resistance efflux transporter
LEPNOIND_01910 5.8e-180 isp O Belongs to the peptidase S8 family
LEPNOIND_01911 5.4e-126 yoqW S Belongs to the SOS response-associated peptidase family
LEPNOIND_01914 1.6e-165 V VanW like protein
LEPNOIND_01915 1.8e-75 V (ABC) transporter
LEPNOIND_01916 4.2e-46 K PadR family transcriptional regulator
LEPNOIND_01917 1.8e-122 yqeB
LEPNOIND_01918 1.6e-103 K Bacterial regulatory proteins, tetR family
LEPNOIND_01919 2.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEPNOIND_01920 7.7e-269 murE 6.3.2.13 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEPNOIND_01921 7.4e-86 M1-1022 1.8.5.2 S DoxX
LEPNOIND_01922 8.5e-21
LEPNOIND_01923 6.4e-58
LEPNOIND_01924 9e-97 K response regulator
LEPNOIND_01926 9.5e-156 S Membrane transport protein
LEPNOIND_01927 2.1e-190 G Xylose isomerase
LEPNOIND_01928 2.9e-143 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_01929 1.1e-164 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_01930 1.8e-234 cycB_1 G Bacterial extracellular solute-binding protein
LEPNOIND_01931 6e-185 S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_01932 1.8e-187 MA20_22185 K Transcriptional regulator, LacI family
LEPNOIND_01933 4.2e-59 S Ketosteroid isomerase-related protein
LEPNOIND_01934 1.1e-144 K Helix-turn-helix domain
LEPNOIND_01935 9.3e-178 fhuD P ABC transporter
LEPNOIND_01936 7.2e-155 dkgB S Aldo/keto reductase family
LEPNOIND_01937 1e-187 K helix_turn _helix lactose operon repressor
LEPNOIND_01938 3.9e-243 hemAT NT chemotaxis protein
LEPNOIND_01939 2.5e-139 S Nucleotidyltransferase domain
LEPNOIND_01940 1.7e-159 3.5.2.6 V beta-lactamase
LEPNOIND_01941 3.4e-126 tcpP 2.7.11.1 KT Forkhead associated domain
LEPNOIND_01942 1.6e-246 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LEPNOIND_01943 1.8e-158 besA S Putative esterase
LEPNOIND_01944 1.8e-184 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPNOIND_01945 1.1e-181 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPNOIND_01946 2.3e-176 feuA P Iron-uptake system-binding protein
LEPNOIND_01947 5.7e-299 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
LEPNOIND_01948 8.1e-179 ectD 1.14.11.55 Q Phytanoyl-CoA dioxygenase (PhyH)
LEPNOIND_01949 5e-199
LEPNOIND_01950 9.6e-256 gerKA EG Spore germination protein
LEPNOIND_01951 1.8e-193 gerKB E Spore germination protein
LEPNOIND_01952 9.9e-208 gerKC S Spore germination B3/ GerAC like, C-terminal
LEPNOIND_01953 0.0 bceB V ABC transporter (permease)
LEPNOIND_01954 5.2e-136 bceA V ABC transporter, ATP-binding protein
LEPNOIND_01955 1.8e-234 msmE7 G Bacterial extracellular solute-binding protein
LEPNOIND_01956 4.2e-121 msmF3 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_01957 1.3e-145 G COG0395 ABC-type sugar transport system, permease component
LEPNOIND_01958 1.5e-269 S Chlorophyllase enzyme
LEPNOIND_01959 2.1e-63 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEPNOIND_01961 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
LEPNOIND_01962 5.2e-184 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEPNOIND_01963 8.4e-45 ptxB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
LEPNOIND_01964 1.7e-208 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
LEPNOIND_01965 6.7e-156 4.1.2.13 G Fructose-bisphosphate aldolase class-II
LEPNOIND_01966 1.6e-102 3.5.1.124 S DJ-1/PfpI family
LEPNOIND_01968 6.4e-159 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylases
LEPNOIND_01969 3.5e-58 S Domain of unknown function (DUF4260)
LEPNOIND_01970 2.4e-69 K helix_turn_helix, mercury resistance
LEPNOIND_01971 1.5e-202 6.3.5.5 S ATP-grasp domain
LEPNOIND_01972 8.4e-212 dapE 3.5.1.18 E Peptidase dimerisation domain
LEPNOIND_01973 2.2e-101 S DinB superfamily
LEPNOIND_01975 6.8e-129 S response regulator aspartate phosphatase
LEPNOIND_01976 0.0 lacA 3.2.1.23 G beta-galactosidase
LEPNOIND_01977 4.4e-238 ganB 3.2.1.89 G arabinogalactan
LEPNOIND_01978 9.3e-150 ganQ P transport
LEPNOIND_01979 1.1e-245 malC P COG1175 ABC-type sugar transport systems, permease components
LEPNOIND_01980 6.1e-238 cycB G COG2182 Maltose-binding periplasmic proteins domains
LEPNOIND_01981 1.6e-185 lacR K Transcriptional regulator
LEPNOIND_01982 2.9e-276
LEPNOIND_01983 0.0
LEPNOIND_01984 1.2e-100
LEPNOIND_01985 9.2e-153 yxxF EG EamA-like transporter family
LEPNOIND_01986 1.3e-148 K Transcriptional regulator
LEPNOIND_01987 1.3e-111 S ABC-2 family transporter protein
LEPNOIND_01988 2.2e-154 V ABC transporter
LEPNOIND_01989 1.7e-184 K Transcriptional regulator
LEPNOIND_01990 7.4e-191 3.5.3.6 E Amidinotransferase
LEPNOIND_01991 4.4e-256 putP E Sodium:solute symporter family
LEPNOIND_01992 2.1e-137 IQ Enoyl-(Acyl carrier protein) reductase
LEPNOIND_01993 2.9e-169 NT chemotaxis protein
LEPNOIND_01994 5.6e-225 S Erythromycin esterase
LEPNOIND_01995 2.2e-90 ykuD S protein conserved in bacteria
LEPNOIND_01996 4.5e-177 S Choline/ethanolamine kinase
LEPNOIND_01997 2.5e-53
LEPNOIND_01998 0.0
LEPNOIND_01999 3.9e-104
LEPNOIND_02000 2.7e-61 K MerR, DNA binding
LEPNOIND_02001 4.1e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPNOIND_02002 1.8e-71 K Transcriptional regulator
LEPNOIND_02003 5.7e-77
LEPNOIND_02004 1.7e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
LEPNOIND_02005 1.7e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
LEPNOIND_02006 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LEPNOIND_02007 6.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LEPNOIND_02008 2.2e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEPNOIND_02009 2.8e-182 rbsR K transcriptional
LEPNOIND_02010 6.9e-173 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
LEPNOIND_02014 3e-31 fic S Fic/DOC family
LEPNOIND_02015 1.5e-39 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
LEPNOIND_02016 3.5e-26 K Cro/C1-type HTH DNA-binding domain
LEPNOIND_02017 5.7e-31
LEPNOIND_02018 5e-103 2.7.7.7 L Domain of unknown function (DUF4357)
LEPNOIND_02019 5e-55 comEA L Helix-hairpin-helix motif
LEPNOIND_02020 1.6e-255 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LEPNOIND_02021 1.8e-124 T Transcriptional regulatory protein, C terminal
LEPNOIND_02022 1.8e-131
LEPNOIND_02023 4.4e-136 S ABC-2 family transporter protein
LEPNOIND_02024 2e-129 V AAA domain, putative AbiEii toxin, Type IV TA system
LEPNOIND_02025 2.6e-103 4.1.1.36, 6.3.2.5 H Flavoprotein
LEPNOIND_02026 1.9e-261 spaC1 V Lanthionine synthetase C-like protein
LEPNOIND_02027 0.0 spaB S Lantibiotic dehydratase, C terminus
LEPNOIND_02029 1.1e-172 XK27_06795 K sequence-specific DNA binding
LEPNOIND_02030 0.0 msbA2 3.6.3.44 V ABC transporter
LEPNOIND_02033 1.3e-54 K Helix-turn-helix XRE-family like proteins
LEPNOIND_02034 1e-102 3.4.22.70 M Sortase family
LEPNOIND_02035 0.0 M1-568 M cell wall anchor domain
LEPNOIND_02036 2.1e-80 T Bacterial transcriptional activator domain
LEPNOIND_02037 5.3e-216 M1-573 T PhoQ Sensor
LEPNOIND_02038 8.8e-15
LEPNOIND_02039 4.4e-186 G phosphotransferase system
LEPNOIND_02040 2.6e-198 rspA 4.2.1.8 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LEPNOIND_02041 5.7e-92 K Helix-turn-helix domain
LEPNOIND_02042 5.3e-24 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEPNOIND_02043 7.1e-297 ramA 3.2.1.40 G Alpha-L-rhamnosidase
LEPNOIND_02044 2.3e-98 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02045 5.2e-119 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02046 2.2e-134 G Bacterial extracellular solute-binding protein
LEPNOIND_02048 8.9e-40 FT AraC family transcriptional regulator
LEPNOIND_02049 6.1e-124 2.7.13.3 T Histidine kinase
LEPNOIND_02050 3.1e-86 S Sulfite exporter TauE/SafE
LEPNOIND_02051 2.4e-119 K Transcriptional regulator
LEPNOIND_02052 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
LEPNOIND_02053 4.5e-54 yqjY K Acetyltransferase (GNAT) domain
LEPNOIND_02054 7.1e-136 yoaT S Protein of unknown function (DUF817)
LEPNOIND_02055 7.4e-30 K Transcriptional regulator
LEPNOIND_02056 5.4e-62 yoaS S Protein of unknown function (DUF2975)
LEPNOIND_02058 1.1e-121 S response regulator aspartate phosphatase
LEPNOIND_02059 2.8e-157 kbaY 4.1.2.13, 4.1.2.40 G in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
LEPNOIND_02060 1.8e-195 gatD 1.1.1.14, 1.1.1.251 C Alcohol dehydrogenase GroES-like domain
LEPNOIND_02061 5.9e-239 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
LEPNOIND_02062 1e-41 gatB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
LEPNOIND_02063 1.7e-79 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEPNOIND_02064 5.6e-141 K COG1349 Transcriptional regulators of sugar metabolism
LEPNOIND_02065 1.3e-179 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
LEPNOIND_02066 3.6e-91 S Protein of unknown function with HXXEE motif
LEPNOIND_02067 2.4e-08
LEPNOIND_02068 2.4e-78
LEPNOIND_02069 1e-84 S Protein of unknown function (DUF1648)
LEPNOIND_02070 4.3e-138 glvR K Helix-turn-helix domain, rpiR family
LEPNOIND_02071 2.2e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEPNOIND_02072 3.4e-255 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEPNOIND_02074 3.3e-258 C FAD dependent oxidoreductase
LEPNOIND_02075 1.5e-147 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02076 8e-171 U Binding-protein-dependent transport system inner membrane component
LEPNOIND_02077 1.6e-246 G Bacterial extracellular solute-binding protein
LEPNOIND_02078 0.0 2.7.13.3 T Histidine kinase
LEPNOIND_02079 4.2e-138 T helix_turn_helix, arabinose operon control protein
LEPNOIND_02080 2.8e-265 G beta-fructofuranosidase activity
LEPNOIND_02082 3.7e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LEPNOIND_02083 1.1e-86 L RAMP superfamily
LEPNOIND_02084 4e-19
LEPNOIND_02085 1.8e-78 L RAMP superfamily
LEPNOIND_02086 5.3e-122 L RAMP superfamily
LEPNOIND_02087 4.7e-88 2.7.7.19 J crispr-associated protein
LEPNOIND_02088 1e-62
LEPNOIND_02089 1.2e-78 S CRISPR-associated endoribonuclease Cas6
LEPNOIND_02090 1.4e-263 yeaV M Belongs to the BCCT transporter (TC 2.A.15) family
LEPNOIND_02092 2.8e-79 yiaB S yiaA/B two helix domain
LEPNOIND_02095 2.4e-181 K Periplasmic binding protein domain
LEPNOIND_02096 3.8e-148 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEPNOIND_02097 1.5e-264 S Tripartite tricarboxylate transporter TctA family
LEPNOIND_02099 9.3e-178 S Tripartite tricarboxylate transporter family receptor
LEPNOIND_02100 4.4e-166 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
LEPNOIND_02101 4e-173 glpX 2.2.1.1, 3.1.3.11, 3.1.3.37 G Bacterial fructose-1,6-bisphosphatase, glpX-encoded
LEPNOIND_02102 5.2e-113 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dak2
LEPNOIND_02103 7.9e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
LEPNOIND_02104 6.9e-47 rpiB 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
LEPNOIND_02110 0.0 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LEPNOIND_02111 1.6e-117 ktrA P COG0569 K transport systems, NAD-binding component
LEPNOIND_02112 6.1e-165 I alpha/beta hydrolase fold
LEPNOIND_02113 1.9e-212 F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEPNOIND_02114 1.5e-97 adk 2.7.4.3 F topology modulation protein
LEPNOIND_02116 9.4e-86 ftnA 1.16.3.2 P Iron-storage protein
LEPNOIND_02117 5.6e-163 yueF S transporter activity
LEPNOIND_02118 4.3e-286 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEPNOIND_02119 1.4e-91 S Peptidase propeptide and YPEB domain
LEPNOIND_02121 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
LEPNOIND_02122 7.5e-207 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
LEPNOIND_02123 2.2e-82 G Tripartite ATP-independent periplasmic transporters, DctQ component
LEPNOIND_02124 2.3e-187 G Bacterial extracellular solute-binding protein, family 7
LEPNOIND_02125 2.1e-174 K helix_turn _helix lactose operon repressor
LEPNOIND_02126 9.4e-141 K helix_turn_helix, mercury resistance
LEPNOIND_02127 0.0 msbA2 3.6.3.44 V ABC transporter
LEPNOIND_02128 2.5e-147 ybbH_2 K Transcriptional regulator
LEPNOIND_02129 4.4e-183 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
LEPNOIND_02130 5.5e-242 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
LEPNOIND_02131 2.9e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
LEPNOIND_02133 1.3e-298 K Propionate catabolism activator
LEPNOIND_02134 1.8e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LEPNOIND_02135 7.2e-237 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEPNOIND_02136 2.9e-201 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
LEPNOIND_02137 3.9e-187 purR15 K Bacterial regulatory proteins, lacI family
LEPNOIND_02138 1.8e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEPNOIND_02139 1e-165 ypbG 2.7.1.2 GK ROK family
LEPNOIND_02140 8.1e-144 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02141 2.6e-169 P COG0395 ABC-type sugar transport system, permease component
LEPNOIND_02142 2.4e-250 G Bacterial extracellular solute-binding protein
LEPNOIND_02143 3.5e-153 manA3 3.2.1.78 GH26 G Endoglucanase
LEPNOIND_02144 4e-40 S Protein of unknown function (DUF2642)
LEPNOIND_02145 3.8e-10
LEPNOIND_02146 6.7e-98 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
LEPNOIND_02147 4.8e-54 fdx5 C 2Fe-2S iron-sulfur cluster binding domain
LEPNOIND_02148 4.5e-20
LEPNOIND_02149 0.0 KT Transcriptional regulator
LEPNOIND_02150 7e-220 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
LEPNOIND_02151 3.3e-234 EG COG2610 H gluconate symporter and related permeases
LEPNOIND_02152 2.4e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
LEPNOIND_02153 7.8e-208 eutG C alcohol dehydrogenase
LEPNOIND_02154 1.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEPNOIND_02155 1.8e-270 EG Bacillus/Clostridium GerA spore germination protein
LEPNOIND_02156 1.3e-53
LEPNOIND_02157 4.1e-89 ectA 2.3.1.178 K L-2,4-diaminobutyric acid acetyltransferase
LEPNOIND_02158 2.3e-248 ectB 2.6.1.76 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEPNOIND_02159 6.1e-75 ectC 4.2.1.108 S Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
LEPNOIND_02160 1.3e-251 G Glycerol-3-phosphate ABC transporter substrate-binding protein
LEPNOIND_02161 2.9e-153 G Xylose isomerase-like TIM barrel
LEPNOIND_02162 1.3e-165 G ABC transporter (permease)
LEPNOIND_02163 8.3e-148 ugpE P PFAM binding-protein-dependent transport systems inner membrane component
LEPNOIND_02164 1.1e-195 3.6.3.20 P Belongs to the ABC transporter superfamily
LEPNOIND_02166 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEPNOIND_02167 7.4e-269 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LEPNOIND_02168 8e-205 vraB 2.3.1.9 I Belongs to the thiolase family
LEPNOIND_02169 1.9e-33 S response regulator aspartate phosphatase
LEPNOIND_02171 2.8e-36 S Family of unknown function (DUF5344)
LEPNOIND_02172 2.4e-237 S LXG domain of WXG superfamily
LEPNOIND_02173 3.9e-45
LEPNOIND_02175 4.2e-144 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPNOIND_02176 2.1e-196 araC2 K Arabinose-binding domain of AraC transcription regulator, N-term
LEPNOIND_02177 1.2e-76 nsrR K Transcriptional regulator
LEPNOIND_02178 2e-241 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LEPNOIND_02179 0.0 glpQ1 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
LEPNOIND_02180 3.5e-205 ugpC 3.6.3.20 P Belongs to the ABC transporter superfamily
LEPNOIND_02181 1e-165 ugpA G ABC transporter (permease)
LEPNOIND_02182 6.2e-143 ugpE P Glycerol-3-phosphate ABC transporter permease
LEPNOIND_02183 1.8e-232 ugpB G Glycerol-3-phosphate ABC transporter substrate-binding protein
LEPNOIND_02184 8.3e-142 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEPNOIND_02185 7.4e-214 yceL EGP Major Facilitator Superfamily
LEPNOIND_02186 2.2e-311 G Bacterial extracellular solute-binding protein
LEPNOIND_02187 1.4e-152 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LEPNOIND_02188 6.5e-93 K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LEPNOIND_02189 1.1e-175 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02190 4.3e-158 G COG0395 ABC-type sugar transport system, permease component
LEPNOIND_02191 6.3e-128 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEPNOIND_02192 2.9e-181 G Xylose isomerase-like TIM barrel
LEPNOIND_02193 5.1e-198 S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_02194 3.7e-105 ykoP G polysaccharide deacetylase
LEPNOIND_02195 6.5e-186
LEPNOIND_02196 4.6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_02197 5.5e-121 K helix_turn_helix, arabinose operon control protein
LEPNOIND_02198 3e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEPNOIND_02199 3.2e-172 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LEPNOIND_02200 9.8e-261 yhdG E amino acid
LEPNOIND_02201 6.9e-181 K AraC-like ligand binding domain
LEPNOIND_02202 0.0 rhaA 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
LEPNOIND_02203 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
LEPNOIND_02204 6.1e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
LEPNOIND_02205 1.7e-227 iolF EGP Major facilitator Superfamily
LEPNOIND_02206 7e-150 K AraC-like ligand binding domain
LEPNOIND_02207 1.1e-230 MA20_16885 S Oxidoreductase family, NAD-binding Rossmann fold
LEPNOIND_02208 2e-222 MA20_16880 EM Protein of unknown function (DUF993)
LEPNOIND_02209 6.2e-159 MA20_16875 G Xylose isomerase-like TIM barrel
LEPNOIND_02210 1.8e-225 S Oxidoreductase family, NAD-binding Rossmann fold
LEPNOIND_02211 0.0 2.7.13.3 T Histidine kinase
LEPNOIND_02212 1.8e-206 T helix_turn_helix, arabinose operon control protein
LEPNOIND_02213 1.3e-251 G Bacterial extracellular solute-binding protein
LEPNOIND_02214 4.2e-175 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02215 1.6e-154 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_02216 1.5e-197 I Acyltransferase family
LEPNOIND_02217 1.2e-239 arlS T His Kinase A (phosphoacceptor) domain
LEPNOIND_02218 1.1e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_02219 1.4e-127 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
LEPNOIND_02221 0.0 E cell wall organization
LEPNOIND_02222 1.2e-246 G Bacterial extracellular solute-binding protein
LEPNOIND_02223 2.5e-148 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02224 9.2e-158 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_02225 4.9e-303 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
LEPNOIND_02226 3.7e-243 G Bacterial extracellular solute-binding protein
LEPNOIND_02227 3e-159 amyD G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02228 4e-153 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_02229 3.8e-108 S Protein of unknown function, DUF624
LEPNOIND_02230 2.4e-175 M1-640 K Transcriptional regulator
LEPNOIND_02231 1.1e-169 rhaR1 K AraC-like ligand binding domain
LEPNOIND_02232 1.3e-140 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LEPNOIND_02233 3.6e-216 egsA 1.1.1.261 C Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LEPNOIND_02234 7.5e-137 araD 4.1.2.17, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LEPNOIND_02235 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
LEPNOIND_02236 2.2e-287 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
LEPNOIND_02237 1.2e-197 chvE G ABC transporter
LEPNOIND_02238 4.8e-285 araG 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LEPNOIND_02239 1.1e-198 gguB G Belongs to the binding-protein-dependent transport system permease family
LEPNOIND_02240 2e-299 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LEPNOIND_02241 2e-51 V ATPases associated with a variety of cellular activities
LEPNOIND_02242 3.7e-27
LEPNOIND_02243 2.4e-81 S Putative small multi-drug export protein
LEPNOIND_02244 2.1e-115 V Transport permease protein
LEPNOIND_02245 2.5e-186 KTV LytTr DNA-binding domain
LEPNOIND_02246 3.8e-48 sugE P Small Multidrug Resistance protein
LEPNOIND_02247 3.2e-59 sugE P Small Multidrug Resistance protein
LEPNOIND_02248 2.3e-99 yvdT K Transcriptional regulator
LEPNOIND_02249 5.7e-245 EGP Major Facilitator Superfamily
LEPNOIND_02250 2.2e-137 iolR K COG1349 Transcriptional regulators of sugar metabolism
LEPNOIND_02251 4.7e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEPNOIND_02252 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LEPNOIND_02253 3.4e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LEPNOIND_02254 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LEPNOIND_02255 2.7e-179 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LEPNOIND_02256 3.6e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LEPNOIND_02257 1.3e-162 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LEPNOIND_02258 1.7e-190 yisS 1.1.1.370 S Oxidoreductase family, NAD-binding Rossmann fold
LEPNOIND_02259 4e-271 yidK S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEPNOIND_02260 3.3e-104 S Protein of unknown function (DUF421)
LEPNOIND_02261 8.1e-246 metY 2.5.1.49 E O-acetylhomoserine
LEPNOIND_02262 1.4e-64 S Putative zinc- or iron-chelating domain
LEPNOIND_02263 1.2e-141 bxlB G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02264 2.9e-165 bxlC G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02265 7.1e-250 bxlD G Bacterial extracellular solute-binding protein
LEPNOIND_02266 1.1e-161 K AraC-like ligand binding domain
LEPNOIND_02267 4.3e-194 yjjN E Alcohol dehydrogenase GroES-like domain
LEPNOIND_02268 4.2e-189 dctP G Bacterial extracellular solute-binding protein, family 7
LEPNOIND_02269 1.6e-82 G Tripartite ATP-independent periplasmic transporters, DctQ component
LEPNOIND_02270 3.3e-223 G Tripartite ATP-independent periplasmic transporter, DctM component
LEPNOIND_02271 5.6e-291 uxaA 4.2.1.7 G Altronate
LEPNOIND_02272 3.8e-295 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
LEPNOIND_02273 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 K transcriptional regulator, MtlR
LEPNOIND_02274 2.3e-159 4.1.2.13 G Fructose-bisphosphate aldolase class-II
LEPNOIND_02275 5.2e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEPNOIND_02276 1.1e-47 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
LEPNOIND_02277 3.3e-168 fruA2 G Phosphotransferase System
LEPNOIND_02278 1.6e-96 5.3.1.15 S Cupin 2, conserved barrel domain protein
LEPNOIND_02280 2.8e-268 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEPNOIND_02281 3e-159 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LEPNOIND_02282 3.1e-104 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LEPNOIND_02283 1.4e-256 KT Transcriptional regulator
LEPNOIND_02284 8.4e-238 E Acyclic terpene utilisation family protein AtuA
LEPNOIND_02285 3e-53
LEPNOIND_02286 5.8e-228 C Citrate transporter
LEPNOIND_02287 2e-83 NT chemotaxis protein
LEPNOIND_02288 1.9e-159 NT chemotaxis protein
LEPNOIND_02289 1.6e-239 V MatE
LEPNOIND_02290 4.7e-12
LEPNOIND_02291 7e-98 S Tetratricopeptide repeat
LEPNOIND_02292 1e-49 3.6.1.55 F NUDIX domain
LEPNOIND_02293 3.5e-97
LEPNOIND_02294 4.7e-131
LEPNOIND_02295 0.0
LEPNOIND_02296 7.2e-53
LEPNOIND_02297 1.7e-185 uxuA 4.2.1.8 G mannonate dehydratase activity
LEPNOIND_02298 4.2e-189 S Tripartite tricarboxylate transporter family receptor
LEPNOIND_02299 6.4e-263 S Tripartite tricarboxylate transporter TctA family
LEPNOIND_02300 8.8e-82 S Tripartite tricarboxylate transporter TctB family
LEPNOIND_02301 3.2e-259 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEPNOIND_02302 4.5e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
LEPNOIND_02303 4.4e-121 ycbG K FCD
LEPNOIND_02304 2.8e-120 K FCD
LEPNOIND_02305 1.1e-215 yeaN P COG2807 Cyanate permease
LEPNOIND_02306 2.9e-66 cdd_2 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
LEPNOIND_02307 1.4e-84 3.4.16.4 V Beta-lactamase
LEPNOIND_02308 3.2e-123 yybG S Pentapeptide repeat-containing protein
LEPNOIND_02309 1.5e-44 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
LEPNOIND_02310 7.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPNOIND_02311 2.5e-50 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
LEPNOIND_02312 2.3e-278 gmuD 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEPNOIND_02313 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
LEPNOIND_02314 3.9e-92 K Bacterial transcription activator, effector binding domain
LEPNOIND_02315 2.2e-87
LEPNOIND_02317 1.9e-30 GK ROK family
LEPNOIND_02318 2.2e-97 yocH 3.5.1.28 M 3D domain
LEPNOIND_02319 2e-215 2.3.1.157, 2.7.7.23 JM Bacterial transferase hexapeptide (six repeats)
LEPNOIND_02320 2.6e-129 K transcriptional
LEPNOIND_02321 1.7e-139 S carbohydrate derivative metabolic process
LEPNOIND_02322 2.1e-83 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_02323 6.1e-244 ykoH T Histidine kinase
LEPNOIND_02324 1.4e-125 ykoI S Peptidase propeptide and YPEB domain
LEPNOIND_02325 1.1e-85 ykoJ S Peptidase propeptide and YPEB domain
LEPNOIND_02326 5.4e-19 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LEPNOIND_02329 3.2e-250 I radical SAM domain protein
LEPNOIND_02330 5.8e-285 H Involved in the biosynthesis of porphyrin-containing compound
LEPNOIND_02331 4.3e-12
LEPNOIND_02332 2.7e-140 yafE Q methyltransferase
LEPNOIND_02333 6.9e-14 1.2.7.12 S Uncharacterised protein family UPF0066
LEPNOIND_02334 2.3e-89 1.2.7.12 S Uncharacterised protein family UPF0066
LEPNOIND_02335 1.9e-223 EGP Major facilitator Superfamily
LEPNOIND_02336 1e-101 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEPNOIND_02337 6e-174 wbpP 5.1.3.2, 5.1.3.7 M GDP-mannose 4,6 dehydratase
LEPNOIND_02338 1.3e-190 M Glycosyl transferases group 1
LEPNOIND_02339 1.2e-157
LEPNOIND_02340 1.7e-133 GT2,GT4 M transferase activity, transferring glycosyl groups
LEPNOIND_02341 9e-175 M transferase activity, transferring glycosyl groups
LEPNOIND_02342 3.5e-131 M Glycosyl transferase family 2
LEPNOIND_02343 1.4e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEPNOIND_02344 1.5e-25 ybbJ K acetyltransferase
LEPNOIND_02345 1.7e-251 M Glycosyltransferase like family 2
LEPNOIND_02346 2.4e-41 S Protein of unknown function (DUF2642)
LEPNOIND_02347 4.5e-26
LEPNOIND_02348 1.1e-242 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
LEPNOIND_02349 1.5e-112 ycsK E anatomical structure formation involved in morphogenesis
LEPNOIND_02350 2.9e-131 K helix_turn_helix isocitrate lyase regulation
LEPNOIND_02351 2.9e-176 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
LEPNOIND_02352 1.7e-111 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
LEPNOIND_02353 5.7e-227 dgoD 4.2.1.6 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LEPNOIND_02354 1.1e-155 S Metallo-beta-lactamase superfamily
LEPNOIND_02355 5.6e-88 S Predicted membrane protein (DUF2243)
LEPNOIND_02356 5.1e-121 S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
LEPNOIND_02357 6.5e-243 T COG0642 Signal transduction histidine kinase
LEPNOIND_02358 1.1e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_02359 9.2e-192 4.2.1.103 K DJ-1/PfpI family
LEPNOIND_02360 1.6e-114 S Predicted membrane protein (DUF2306)
LEPNOIND_02361 4e-209 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
LEPNOIND_02362 3e-78 S VanZ like family
LEPNOIND_02363 8.1e-111 wrbA 1.6.5.2 S Belongs to the WrbA family
LEPNOIND_02364 8.3e-93 2.3.1.128 K Acetyltransferase (GNAT) family
LEPNOIND_02365 8.2e-137 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LEPNOIND_02366 0.0 V SNF2 family N-terminal domain
LEPNOIND_02367 2.4e-12 S Domain of unknown function (DUF5082)
LEPNOIND_02368 2.5e-08 S Family of unknown function (DUF5344)
LEPNOIND_02369 2.3e-255 S LXG domain of WXG superfamily
LEPNOIND_02370 1.3e-108
LEPNOIND_02371 6.7e-97
LEPNOIND_02372 1.1e-149
LEPNOIND_02373 3.4e-283 E Sodium:solute symporter family
LEPNOIND_02374 4.6e-23
LEPNOIND_02375 4.5e-230 2.8.3.16, 2.8.3.20 C acyl-CoA transferases carnitine dehydratase
LEPNOIND_02376 2.7e-117 K FCD domain
LEPNOIND_02377 8.3e-165 4.1.3.4, 4.1.3.46 E Hydroxymethylglutaryl-CoA lyase
LEPNOIND_02378 1.3e-213 1.4.1.9 G Transmembrane secretion effector
LEPNOIND_02380 3.2e-102 gntR K RpiR family transcriptional regulator
LEPNOIND_02381 7.4e-181 EG COG2610 H gluconate symporter and related permeases
LEPNOIND_02382 9.1e-127 garR 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LEPNOIND_02383 1.1e-187 S Putative nucleotide-binding of sugar-metabolising enzyme
LEPNOIND_02384 1.6e-224 abgB 3.5.1.47 S amidohydrolase
LEPNOIND_02385 8e-157 metQ M Belongs to the nlpA lipoprotein family
LEPNOIND_02386 3.3e-113 P COG2011 ABC-type metal ion transport system, permease component
LEPNOIND_02387 3e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEPNOIND_02388 1.9e-172 K helix_turn_helix, arabinose operon control protein
LEPNOIND_02390 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
LEPNOIND_02391 0.0 aguA 3.2.1.139 G Belongs to the glycosyl hydrolase 67 family
LEPNOIND_02392 3.9e-176 lplB G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02393 1.7e-154 lplC G COG0395 ABC-type sugar transport system, permease component
LEPNOIND_02394 0.0 G Bacterial extracellular solute-binding protein
LEPNOIND_02395 2.4e-122 S Protein of unknown function, DUF624
LEPNOIND_02396 6.8e-201 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
LEPNOIND_02397 9.7e-29 D nuclear chromosome segregation
LEPNOIND_02398 3.1e-220 hutI Q COG1228 Imidazolonepropionase and related amidohydrolases
LEPNOIND_02399 1.2e-205 Q COG1228 Imidazolonepropionase and related amidohydrolases
LEPNOIND_02400 1.9e-305 E COG0747 ABC-type dipeptide transport system, periplasmic component
LEPNOIND_02401 9.9e-172 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_02402 3.5e-155 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_02403 7.6e-191 oppD P Belongs to the ABC transporter superfamily
LEPNOIND_02404 3.7e-190 ddpF E Belongs to the ABC transporter superfamily
LEPNOIND_02405 1e-176 S Protein of unknown function (DUF1177)
LEPNOIND_02406 1.3e-243 3.5.1.18 E Acetylornithine deacetylase
LEPNOIND_02407 3.6e-137 K Transcriptional regulator
LEPNOIND_02408 1.6e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
LEPNOIND_02409 7.6e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G xylulose kinase
LEPNOIND_02410 9.5e-205 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
LEPNOIND_02411 1.1e-220 xylR GK ROK family
LEPNOIND_02412 6.1e-125 MA20_14010 S Trehalose utilisation
LEPNOIND_02413 1.1e-222 yrbE S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_02414 2.3e-284 KT PucR C-terminal helix-turn-helix domain
LEPNOIND_02415 1.2e-109 hyuE 5.1.99.3 E Asp/Glu/Hydantoin racemase
LEPNOIND_02416 2.6e-286 S OPT oligopeptide transporter protein
LEPNOIND_02417 1.1e-187 S Protein of unknown function (DUF917)
LEPNOIND_02418 2.1e-163 S Protein of unknown function (DUF1177)
LEPNOIND_02419 7.5e-115 aroM E AroM protein
LEPNOIND_02420 1.3e-176 E Thermophilic metalloprotease (M29)
LEPNOIND_02421 9.6e-225 EGP Major facilitator Superfamily
LEPNOIND_02422 3.1e-30 dmpI 5.3.2.6 S Tautomerase enzyme
LEPNOIND_02423 7.3e-46 chrA P chromate transporter, chromate ion transporter
LEPNOIND_02424 2.4e-156 chrA P chromate transporter, chromate ion transporter
LEPNOIND_02426 1.8e-44 M1-594 S Thiamine-binding protein
LEPNOIND_02427 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEPNOIND_02428 2.6e-242
LEPNOIND_02430 6.6e-238 gntT EG gluconate transmembrane transporter activity
LEPNOIND_02431 1.4e-167 2.7.1.196, 2.7.1.205 K sequence-specific DNA binding
LEPNOIND_02432 4e-124 S protein conserved in bacteria
LEPNOIND_02433 6e-54
LEPNOIND_02435 3.9e-93 ssuE 1.5.1.38 S FMN reductase
LEPNOIND_02436 1.5e-180 P ABC transporter substrate-binding protein
LEPNOIND_02437 1.9e-211 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
LEPNOIND_02438 4.4e-135 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEPNOIND_02439 8.2e-134 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
LEPNOIND_02440 2.1e-94 K Transcriptional regulator PadR-like family
LEPNOIND_02441 1.4e-161 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
LEPNOIND_02442 5.2e-123 K FCD
LEPNOIND_02443 1.7e-223 S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_02444 3.9e-201 S oxidoreductase
LEPNOIND_02445 6.2e-185 G Bacterial extracellular solute-binding protein, family 7
LEPNOIND_02446 2.8e-77 G Tripartite ATP-independent periplasmic transporters, DctQ component
LEPNOIND_02447 2.7e-212 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
LEPNOIND_02448 2.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LEPNOIND_02449 1.9e-219 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LEPNOIND_02450 7.1e-187 cysP P phosphate transporter
LEPNOIND_02451 5.5e-112 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
LEPNOIND_02452 1.7e-276 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LEPNOIND_02453 1.3e-142 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 C CbiX
LEPNOIND_02454 8.3e-111 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
LEPNOIND_02455 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LEPNOIND_02456 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LEPNOIND_02457 7.4e-20
LEPNOIND_02458 1e-159 V ABC transporter
LEPNOIND_02459 1.8e-60 gntR1 K GntR family transcriptional regulator
LEPNOIND_02460 1.7e-218 mii 5.3.3.6 S PrpF protein
LEPNOIND_02461 6.1e-68 S Tripartite tricarboxylate transporter TctB family
LEPNOIND_02462 1.4e-262 S Tripartite tricarboxylate transporter TctA family
LEPNOIND_02463 3.9e-212 S Tripartite tricarboxylate transporter family receptor
LEPNOIND_02464 1.3e-167 yraN K Transcriptional regulator
LEPNOIND_02465 4.3e-200 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
LEPNOIND_02466 3e-292 C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
LEPNOIND_02467 3.6e-196 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
LEPNOIND_02468 1.1e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LEPNOIND_02469 4.8e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPNOIND_02470 5.3e-104 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LEPNOIND_02471 7e-104 tetR K Bacterial regulatory proteins, tetR family
LEPNOIND_02472 3.8e-181 ybcL EGP Major facilitator Superfamily
LEPNOIND_02473 8.1e-166 arsB P Arsenic resistance protein
LEPNOIND_02474 6e-97
LEPNOIND_02475 1.6e-131 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LEPNOIND_02476 6.3e-45 2.7.1.196, 2.7.1.205 G phosphotransferase system
LEPNOIND_02477 3.5e-52 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
LEPNOIND_02478 2.1e-241 ywbA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEPNOIND_02479 1.1e-253 celF 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEPNOIND_02480 1.1e-138 chbG 2.7.1.196, 2.7.1.205, 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
LEPNOIND_02481 6.1e-137 K UTRA
LEPNOIND_02482 0.0 chiA 3.2.1.14 GH18 G Glycoside Hydrolase Family 18
LEPNOIND_02483 5.1e-42 S Family of unknown function (DUF5391)
LEPNOIND_02484 9.3e-56 S Protein of unknown function (DUF1093)
LEPNOIND_02485 1e-226 ybfB G COG0477 Permeases of the major facilitator superfamily
LEPNOIND_02486 5.7e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LEPNOIND_02487 1.8e-250 kynU 3.7.1.3 E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
LEPNOIND_02488 2.4e-118 kynB 3.5.1.9 S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LEPNOIND_02489 1.5e-160 kynA 1.13.11.11 E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
LEPNOIND_02490 9.5e-53 S Domain of unknown function (DUF4352)
LEPNOIND_02491 2.2e-210 E Spore germination protein
LEPNOIND_02493 1.5e-222 gerKC S spore germination
LEPNOIND_02494 4.8e-282 gerKA EG Spore germination protein
LEPNOIND_02495 7.5e-135 ygbI K DeoR C terminal sensor domain
LEPNOIND_02496 6.8e-237 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
LEPNOIND_02497 2.5e-186 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
LEPNOIND_02498 1.5e-218 gntP EG GntP family permease
LEPNOIND_02499 6.7e-153 araQ5 P PFAM binding-protein-dependent transport systems inner membrane component
LEPNOIND_02500 1.4e-159 cebF P PFAM binding-protein-dependent transport systems inner membrane component
LEPNOIND_02501 7.1e-231 lacE3 G PFAM extracellular solute-binding protein family 1
LEPNOIND_02503 2.4e-229 citH C Citrate transporter
LEPNOIND_02504 2.4e-130 T Response regulator receiver domain
LEPNOIND_02505 2.2e-293 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LEPNOIND_02506 5.2e-253 argE 3.5.1.16 E Acetylornithine deacetylase
LEPNOIND_02507 1.3e-125 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LEPNOIND_02508 9.1e-195 pslL G Acyltransferase family
LEPNOIND_02509 3.3e-161 3.13.1.3 P YhfZ C-terminal domain
LEPNOIND_02510 4.2e-56 S PRD domain
LEPNOIND_02511 1.2e-58 yhfU S Protein of unknown function DUF2620
LEPNOIND_02512 1.6e-222 yhfT S Protein of unknown function
LEPNOIND_02513 5e-173 php S Phosphotriesterase family
LEPNOIND_02514 1e-204 2.9.1.1 E Cys/Met metabolism PLP-dependent enzyme
LEPNOIND_02515 4e-220 yhfX E Alanine racemase, N-terminal domain
LEPNOIND_02516 4.9e-229 yhfW G Metalloenzyme superfamily
LEPNOIND_02518 0.0 O DnaJ molecular chaperone homology domain
LEPNOIND_02519 0.0 hscC O Hsp70 protein
LEPNOIND_02520 1.9e-141 IQ Enoyl-(Acyl carrier protein) reductase
LEPNOIND_02521 2.1e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LEPNOIND_02522 7.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LEPNOIND_02523 3e-175 agpT K AraC-like ligand binding domain
LEPNOIND_02524 7e-250 ugpB1 G Bacterial extracellular solute-binding protein
LEPNOIND_02525 2.4e-148 M1-465 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_02526 2.3e-159 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_02527 1.2e-48 esxA S Belongs to the WXG100 family
LEPNOIND_02528 7.2e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
LEPNOIND_02529 4.1e-213 essB S WXG100 protein secretion system (Wss), protein YukC
LEPNOIND_02530 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LEPNOIND_02531 0.0 esaA S domain protein
LEPNOIND_02532 7.9e-71 S Family of unknown function (DUF5383)
LEPNOIND_02533 2.4e-44
LEPNOIND_02534 4.3e-47
LEPNOIND_02535 9.9e-46
LEPNOIND_02536 1.5e-283 S nuclease activity
LEPNOIND_02537 2.3e-07
LEPNOIND_02538 4.6e-88
LEPNOIND_02539 4.4e-09
LEPNOIND_02542 8.9e-07
LEPNOIND_02543 2.7e-47
LEPNOIND_02544 5.4e-10 S nuclease activity
LEPNOIND_02548 3.5e-51
LEPNOIND_02550 3.2e-49
LEPNOIND_02552 3.3e-171 glcA G Glycoside hydrolase family 16
LEPNOIND_02553 7.1e-17
LEPNOIND_02558 3.1e-130 lolD-2 V COG1136 ABC-type antimicrobial peptide transport system, ATPase component
LEPNOIND_02559 0.0 Q FtsX-like permease family
LEPNOIND_02560 3.2e-89 K Transcriptional regulator PadR-like family
LEPNOIND_02561 3.3e-80 2.3.1.128 K Acetyltransferase (GNAT) domain
LEPNOIND_02562 1.7e-140 K Helix-turn-helix domain, rpiR family
LEPNOIND_02563 7.6e-118 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LEPNOIND_02564 4e-284 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEPNOIND_02565 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LEPNOIND_02566 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEPNOIND_02567 0.0 narH 1.7.5.1 C Nitrate reductase, beta
LEPNOIND_02568 1.3e-116 narJ C Nitrate reductase delta subunit
LEPNOIND_02569 2e-126 narI 1.7.5.1 C nitrate reductase, gamma subunit
LEPNOIND_02570 2.4e-83 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
LEPNOIND_02571 3.6e-199 nreB 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LEPNOIND_02572 1.7e-114 nreC T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEPNOIND_02573 2.9e-279 narK P COG2223 Nitrate nitrite transporter
LEPNOIND_02574 2.1e-129 ywiC S YwiC-like protein
LEPNOIND_02575 0.0 G Bacterial extracellular solute-binding protein
LEPNOIND_02576 3.7e-307 2.7.13.3 T Histidine kinase
LEPNOIND_02577 9.4e-228 T cheY-homologous receiver domain
LEPNOIND_02578 2e-172 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_02579 3.5e-160 U Binding-protein-dependent transport system inner membrane component
LEPNOIND_02580 7.4e-39
LEPNOIND_02581 8.4e-102 yvrI K RNA polymerase
LEPNOIND_02582 8.9e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
LEPNOIND_02583 2.4e-250 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LEPNOIND_02584 1.3e-170 agpT K AraC-like ligand binding domain
LEPNOIND_02585 9.4e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
LEPNOIND_02586 1.9e-206 desK 2.7.13.3 T Histidine kinase
LEPNOIND_02587 9e-107 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEPNOIND_02588 5.6e-189 mgtE P Acts as a magnesium transporter
LEPNOIND_02589 4.6e-76 K transcriptional
LEPNOIND_02590 5.5e-56
LEPNOIND_02591 2.5e-89 3.1.1.29 K -acetyltransferase
LEPNOIND_02592 8e-246 aspT EK Alanine-glyoxylate amino-transferase
LEPNOIND_02593 2e-82 yvbK 3.1.3.25 K acetyltransferase
LEPNOIND_02594 2.8e-145 map 3.4.11.18 E Methionine aminopeptidase
LEPNOIND_02595 4.2e-80 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LEPNOIND_02596 9.2e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LEPNOIND_02597 5.7e-200 cdaR KT Sugar diacid utilization regulator
LEPNOIND_02598 1.7e-196 yetN S Protein of unknown function (DUF3900)
LEPNOIND_02599 3.2e-120
LEPNOIND_02600 1.8e-113 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEPNOIND_02601 1e-187 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LEPNOIND_02602 6.4e-156 hisJ3 3.1.3.15 E PHP domain
LEPNOIND_02603 0.0 vpr O Belongs to the peptidase S8 family
LEPNOIND_02604 6e-95 3.4.21.89 U Signal peptidase
LEPNOIND_02605 2.8e-128
LEPNOIND_02606 1.6e-94 tag 3.2.2.20 L Methyladenine glycosylase
LEPNOIND_02607 6.3e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LEPNOIND_02608 7.4e-178 S Phosphotransferase system, EIIC
LEPNOIND_02609 7.5e-141 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LEPNOIND_02610 1.1e-172 yfhM S Alpha beta hydrolase
LEPNOIND_02611 1.6e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEPNOIND_02613 7e-201 aprE 3.4.21.62 O Belongs to the peptidase S8 family
LEPNOIND_02614 2e-233 K Helix-turn-helix XRE-family like proteins
LEPNOIND_02615 1.4e-112 cwlK M Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin
LEPNOIND_02616 1.2e-250 yeeF E Amino acid permease
LEPNOIND_02617 2.5e-163 sseA 2.8.1.1, 2.8.1.2 P sulfurtransferase
LEPNOIND_02618 1.8e-234 QT Transcriptional regulator
LEPNOIND_02619 9e-201 ald 1.4.1.1 E Belongs to the AlaDH PNT family
LEPNOIND_02620 4.5e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
LEPNOIND_02621 8.1e-160 rarD S -transporter
LEPNOIND_02622 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEPNOIND_02623 1e-148 glnH ET Belongs to the bacterial solute-binding protein 3 family
LEPNOIND_02624 7.1e-110 gluC P ABC transporter
LEPNOIND_02625 1.5e-107 glnP P ABC transporter
LEPNOIND_02626 3.3e-158 ycbB1 T YcbB domain
LEPNOIND_02627 5.7e-236 2.7.13.3 T Histidine kinase-like ATPases
LEPNOIND_02628 1.8e-150 dppA E D-aminopeptidase
LEPNOIND_02629 9.4e-164 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_02630 3.3e-172 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_02631 1.8e-184 dppD P Belongs to the ABC transporter superfamily
LEPNOIND_02632 0.0 dppE E ABC transporter substrate-binding protein
LEPNOIND_02633 6.8e-178 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LEPNOIND_02634 1.5e-174 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LEPNOIND_02635 1.9e-186 ykfD E Belongs to the ABC transporter superfamily
LEPNOIND_02636 3.1e-59 hxlR K transcriptional
LEPNOIND_02637 7.1e-112 S Nitroreductase family
LEPNOIND_02638 1.7e-130 T PhoQ Sensor
LEPNOIND_02639 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LEPNOIND_02640 9.3e-66 mnhB2 P antiporter activity
LEPNOIND_02641 4.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEPNOIND_02642 7.6e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEPNOIND_02643 1.7e-85 mrpE P Na+/H+ ion antiporter subunit
LEPNOIND_02644 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEPNOIND_02645 5.4e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
LEPNOIND_02646 1.1e-161 S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
LEPNOIND_02647 3.5e-193 G Xylose isomerase
LEPNOIND_02648 8.3e-193 S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_02649 6.9e-141 G Xylose isomerase-like TIM barrel
LEPNOIND_02650 2.2e-218 S Winged helix DNA-binding domain
LEPNOIND_02651 2.9e-111 S Integral membrane protein
LEPNOIND_02652 1.1e-47
LEPNOIND_02653 2.8e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LEPNOIND_02654 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LEPNOIND_02655 1.2e-101 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEPNOIND_02656 1.6e-132 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
LEPNOIND_02657 2e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEPNOIND_02658 1.8e-187 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
LEPNOIND_02659 1.4e-231 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEPNOIND_02660 8e-25 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LEPNOIND_02661 4.4e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
LEPNOIND_02662 3e-145 rsbR T Positive regulator of sigma-B
LEPNOIND_02663 1.5e-53 rsbS T antagonist
LEPNOIND_02664 7.2e-74 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LEPNOIND_02665 2.3e-187 rsbU 3.1.3.3 KT phosphatase
LEPNOIND_02666 3.7e-54 rsbV T Belongs to the anti-sigma-factor antagonist family
LEPNOIND_02667 3.3e-83 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LEPNOIND_02668 4.3e-141 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEPNOIND_02669 3.1e-118 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
LEPNOIND_02670 0.0 yhgF K COG2183 Transcriptional accessory protein
LEPNOIND_02671 3.9e-08
LEPNOIND_02672 4.7e-87 ydcK S Belongs to the SprT family
LEPNOIND_02680 2.7e-09 K transcriptional regulator
LEPNOIND_02681 0.0 ydfJ S drug exporters of the RND superfamily
LEPNOIND_02682 8e-94 yokH G SMI1 / KNR4 family
LEPNOIND_02683 5e-60 Q ubiE/COQ5 methyltransferase family
LEPNOIND_02684 2.5e-97 yrkC G Cupin domain
LEPNOIND_02685 1.9e-141 S TraX protein
LEPNOIND_02686 1.6e-171 mviM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
LEPNOIND_02687 5.1e-30 cspL K Cold shock
LEPNOIND_02688 8e-79 carD K Transcription factor
LEPNOIND_02689 1.3e-54 arsR K transcriptional
LEPNOIND_02690 5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LEPNOIND_02693 1e-239 oxdD 4.1.1.2 G Oxalate decarboxylase
LEPNOIND_02695 1.7e-167 catE 1.13.11.2 S glyoxalase
LEPNOIND_02696 1.6e-117 ydhC K FCD
LEPNOIND_02697 2.7e-199 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
LEPNOIND_02698 3.9e-65 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEPNOIND_02699 7.8e-199 K ArsR family transcriptional regulator
LEPNOIND_02700 4.9e-224 EGP Major facilitator Superfamily
LEPNOIND_02701 2.6e-129 1.14.12.17 C Oxidoreductase NAD-binding domain
LEPNOIND_02702 0.0 L ABC transporter
LEPNOIND_02703 3.9e-74 yndB K Activator of Hsp90 ATPase homolog 1-like protein
LEPNOIND_02704 3e-56 smtB K helix_turn_helix, Arsenical Resistance Operon Repressor
LEPNOIND_02706 3.4e-64 frataxin S Domain of unknown function (DU1801)
LEPNOIND_02707 2.7e-49 azlD E Branched-chain amino acid transport protein (AzlD)
LEPNOIND_02708 2.7e-126 azlC E AzlC protein
LEPNOIND_02709 1.5e-74 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEPNOIND_02710 8.1e-72 phnB5 S 3-demethylubiquinone-9 3-methyltransferase
LEPNOIND_02711 3.6e-235 3.1.3.41, 3.6.1.55 F Belongs to the Nudix hydrolase family
LEPNOIND_02712 1.2e-67 2.3.1.128 J L-PSP family endoribonuclease
LEPNOIND_02713 0.0 K transcriptional regulator, MtlR
LEPNOIND_02714 4.7e-157 4.1.2.13 G Fructose-bisphosphate aldolase class-II
LEPNOIND_02715 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LEPNOIND_02716 8.4e-167 aadK G Streptomycin adenylyltransferase
LEPNOIND_02717 4.7e-99
LEPNOIND_02719 1.2e-26
LEPNOIND_02724 2.8e-88 C HEAT repeats
LEPNOIND_02725 1.9e-44 CP_0264 3.2.2.10 S Belongs to the LOG family
LEPNOIND_02726 1.6e-71 S Bacterial PH domain
LEPNOIND_02727 5.9e-185 3.4.11.5 I Alpha beta hydrolase
LEPNOIND_02728 1.2e-30 mutT 3.6.1.55 F NUDIX domain
LEPNOIND_02729 6.7e-07 S Family of unknown function (DUF5345)
LEPNOIND_02730 1.1e-95 sigY K Belongs to the sigma-70 factor family. ECF subfamily
LEPNOIND_02731 1.4e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LEPNOIND_02732 1.3e-168 yxlF V ABC transporter, ATP-binding protein
LEPNOIND_02733 5.9e-10 yxlE S Phospholipase_D-nuclease N-terminal
LEPNOIND_02734 6.4e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
LEPNOIND_02735 1.7e-139
LEPNOIND_02736 4.8e-216 blt9 EGP Major facilitator Superfamily
LEPNOIND_02737 4e-86 S Domain of unknown function (DUF4188)
LEPNOIND_02738 1.1e-97 padR K Virulence activator alpha C-term
LEPNOIND_02739 7.7e-160 ydeE K AraC family transcriptional regulator
LEPNOIND_02740 1.8e-281 metP S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LEPNOIND_02742 5.3e-56 yitW S metal-sulfur cluster biosynthetic enzyme
LEPNOIND_02744 1.6e-144 ywfM EG EamA-like transporter family
LEPNOIND_02746 7.9e-126 yeeN K transcriptional regulatory protein
LEPNOIND_02747 1.2e-154 xth 3.1.11.2 L exodeoxyribonuclease III
LEPNOIND_02748 6.1e-249 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
LEPNOIND_02749 2.2e-99 gmhB 3.1.3.82, 3.1.3.83 E D,D-heptose 1,7-bisphosphate phosphatase
LEPNOIND_02750 2.7e-162 asbF 4.2.1.118 G Xylose isomerase-like TIM barrel
LEPNOIND_02751 1.2e-190 asbE IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEPNOIND_02752 1.7e-41 asbD IQ Phosphopantetheine attachment site
LEPNOIND_02753 5.6e-236 asbC 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LEPNOIND_02754 0.0 asbB Q IucA / IucC family
LEPNOIND_02755 0.0 iucA 6.3.2.38 Q Siderophore biosynthesis protein
LEPNOIND_02756 5.8e-58 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LEPNOIND_02757 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
LEPNOIND_02758 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
LEPNOIND_02759 2.5e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEPNOIND_02760 4.7e-137 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
LEPNOIND_02761 2.5e-186 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEPNOIND_02762 3.1e-104 yvdT K Transcriptional regulator
LEPNOIND_02763 5.4e-236 els S Acetyltransferase
LEPNOIND_02764 1.3e-88 lytE2 M COG1388 FOG LysM repeat
LEPNOIND_02765 4e-107 yvdD_1 3.2.2.10 S Belongs to the LOG family
LEPNOIND_02766 1.3e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LEPNOIND_02767 2.1e-143 ykoC P Cobalt transport protein
LEPNOIND_02768 1.5e-272 ykoD 3.6.3.24 P ABC transporter
LEPNOIND_02769 1.8e-102 ykoE S ABC-type cobalt transport system, permease component
LEPNOIND_02770 2.5e-152 ysaA S HAD-hyrolase-like
LEPNOIND_02771 5.3e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LEPNOIND_02772 1.9e-158 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEPNOIND_02773 6.8e-174 M 3D domain
LEPNOIND_02774 6.8e-137 M 3D domain
LEPNOIND_02775 2.3e-133 yodH Q Methyltransferase
LEPNOIND_02776 1.5e-269 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEPNOIND_02777 1.7e-96 S Protein of unknown function (DUF1706)
LEPNOIND_02778 1.2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEPNOIND_02780 1.2e-51
LEPNOIND_02781 2.6e-143 Q Methyltransferase domain
LEPNOIND_02782 3.5e-76 yjcF S Acetyltransferase (GNAT) domain
LEPNOIND_02783 1.4e-37
LEPNOIND_02784 4.8e-240 rtcB 6.5.1.3 S tRNA-splicing ligase RtcB
LEPNOIND_02785 4.6e-88 M Acetyltransferase (GNAT) domain
LEPNOIND_02786 5e-75 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
LEPNOIND_02787 2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEPNOIND_02788 2.9e-60 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
LEPNOIND_02789 9.6e-158 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
LEPNOIND_02790 1.7e-213 tcaB EGP Major facilitator Superfamily
LEPNOIND_02791 5.9e-118 yugP S Zn-dependent protease
LEPNOIND_02792 2.7e-140 S Sporulation protein YpjB (SpoYpjB)
LEPNOIND_02793 3.1e-110 ypjA S membrane
LEPNOIND_02794 4.2e-149 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
LEPNOIND_02795 7.7e-123 petB C COG1290 Cytochrome b subunit of the bc complex
LEPNOIND_02796 7.4e-91 qcrA C Menaquinol-cytochrome c reductase
LEPNOIND_02797 1.2e-82 ypiF S Protein of unknown function (DUF2487)
LEPNOIND_02798 1.2e-97 ypiB S Belongs to the UPF0302 family
LEPNOIND_02799 1.9e-231 S COG0457 FOG TPR repeat
LEPNOIND_02800 4.8e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LEPNOIND_02801 1.1e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LEPNOIND_02802 3.4e-208 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LEPNOIND_02803 2.4e-147 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LEPNOIND_02804 2.3e-226 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LEPNOIND_02805 2.9e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E phosphoribosylanthranilate isomerase activity
LEPNOIND_02806 3.6e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LEPNOIND_02807 1e-187 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LEPNOIND_02808 1.3e-284 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LEPNOIND_02809 3.3e-59 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LEPNOIND_02810 1.5e-197 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LEPNOIND_02811 4.1e-220 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LEPNOIND_02812 8.4e-145 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
LEPNOIND_02813 1.4e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LEPNOIND_02814 8.6e-184 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEPNOIND_02815 3.7e-162 mqnA 1.21.98.1, 4.2.1.151 S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LEPNOIND_02816 3.9e-159 ubiA 2.5.1.39 H UbiA prenyltransferase family
LEPNOIND_02817 3.3e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LEPNOIND_02818 4.3e-58 hepS 2.5.1.30 H heptaprenyl diphosphate synthase
LEPNOIND_02819 1.6e-35 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LEPNOIND_02820 7e-101 folE 3.5.4.16 H GTP cyclohydrolase
LEPNOIND_02821 2e-280 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LEPNOIND_02822 2.5e-135 yphF
LEPNOIND_02824 9.4e-40 S Stage VI sporulation protein F
LEPNOIND_02825 2.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LEPNOIND_02826 1.8e-102 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEPNOIND_02827 6.1e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LEPNOIND_02828 3.3e-11 yphA
LEPNOIND_02829 2.6e-203 rpsA 1.17.7.4 J Ribosomal protein S1
LEPNOIND_02830 2.3e-107 plsC 2.3.1.51, 2.7.4.25 I 1-acyl-sn-glycerol-3-phosphate acyltransferase
LEPNOIND_02831 2.4e-131 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LEPNOIND_02832 5.5e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
LEPNOIND_02833 3e-167 sleB 3.5.1.28 M Spore cortex-lytic enzyme
LEPNOIND_02834 0.0 metH 2.1.1.13 E Methionine synthase
LEPNOIND_02835 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LEPNOIND_02836 8.8e-209 metB 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
LEPNOIND_02837 2.4e-25
LEPNOIND_02838 2.6e-112 prsW S Involved in the degradation of specific anti-sigma factors
LEPNOIND_02839 7.5e-180 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LEPNOIND_02840 1.1e-181 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
LEPNOIND_02841 5.5e-239 gdhA 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LEPNOIND_02842 6.9e-192
LEPNOIND_02843 9.6e-272 T PhoQ Sensor
LEPNOIND_02844 1.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_02845 1.5e-109 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LEPNOIND_02846 7.1e-172 merR K MerR family transcriptional regulator
LEPNOIND_02847 2e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
LEPNOIND_02848 4.2e-225 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LEPNOIND_02850 3.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEPNOIND_02851 5.6e-197 cpoA GT4 M Glycosyl transferases group 1
LEPNOIND_02852 1.2e-227 mgs 2.4.1.337 GT4 M Glycosyl Transferase
LEPNOIND_02854 7e-40 sinR K Helix-turn-helix XRE-family like proteins
LEPNOIND_02855 4.4e-52 K Helix-turn-helix XRE-family like proteins
LEPNOIND_02856 3e-08 ypbF S Protein of unknown function (DUF2663)
LEPNOIND_02858 6.8e-104 ypbD S metal-dependent membrane protease
LEPNOIND_02859 4.8e-274 recQ 3.6.4.12 L DNA helicase
LEPNOIND_02860 3.9e-190 ypbB 5.1.3.1 S protein conserved in bacteria
LEPNOIND_02861 5.9e-44 fer C Ferredoxin
LEPNOIND_02862 8.4e-301 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEPNOIND_02863 1.1e-261 nox 1.6.3.4 P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEPNOIND_02864 2.6e-135 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LEPNOIND_02866 1.4e-98 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
LEPNOIND_02867 1.1e-141 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LEPNOIND_02868 1.4e-190 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPNOIND_02870 0.0 resE 2.7.13.3 T Histidine kinase
LEPNOIND_02871 9e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_02872 2e-222 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LEPNOIND_02873 1.4e-303 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
LEPNOIND_02874 3.4e-97 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LEPNOIND_02875 3.7e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEPNOIND_02876 1.4e-74 spmB S Spore maturation protein
LEPNOIND_02877 1.9e-101 spmA S Spore maturation protein
LEPNOIND_02878 5.5e-214 dacB 3.4.16.4 M Belongs to the peptidase S11 family
LEPNOIND_02879 1.2e-55 spoVAE S stage V sporulation protein
LEPNOIND_02880 1.1e-192 spoVAD I Stage V sporulation protein AD
LEPNOIND_02881 8.1e-79 spoVAC S stage V sporulation protein AC
LEPNOIND_02882 7.1e-45 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEPNOIND_02883 4.2e-124 S membrane
LEPNOIND_02884 6.8e-45 S ATP synthase, subunit b
LEPNOIND_02885 1.1e-308 ubiB S ABC1 family
LEPNOIND_02886 2.6e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEPNOIND_02887 1.4e-169 sodA 1.15.1.1 P Superoxide dismutase
LEPNOIND_02888 2.7e-296 aldA C Belongs to the aldehyde dehydrogenase family
LEPNOIND_02889 8e-105 K Uncharacterized protein conserved in bacteria (DUF2087)
LEPNOIND_02890 1.6e-97 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEPNOIND_02891 2.7e-126 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEPNOIND_02892 2.6e-85 ypuF S Domain of unknown function (DUF309)
LEPNOIND_02893 1.6e-82 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LEPNOIND_02894 3e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LEPNOIND_02895 2e-112 ribE 2.5.1.9 H Riboflavin synthase
LEPNOIND_02896 2e-194 echA9 1.1.1.31, 3.1.2.4, 4.2.1.17 I 3-hydroxyisobutyryl-CoA hydrolase
LEPNOIND_02897 1.3e-276 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEPNOIND_02898 5.1e-162 hgd 1.1.1.31, 1.1.1.60 I 3-hydroxyisobutyrate dehydrogenase
LEPNOIND_02899 2.3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LEPNOIND_02900 1.7e-273 prpD 4.2.1.79 S 2-methylcitrate dehydratase
LEPNOIND_02901 6.9e-209 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
LEPNOIND_02903 1.7e-196 S Psort location CytoplasmicMembrane, score
LEPNOIND_02904 1.1e-161 ccpC K Transcriptional regulator
LEPNOIND_02905 1.4e-80 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEPNOIND_02906 8e-257 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEPNOIND_02907 4.8e-271 spoVAF EG Stage V sporulation protein AF
LEPNOIND_02908 2.6e-106 spoVAEA S Stage V sporulation protein AE
LEPNOIND_02909 5.1e-57 spoVAEB S Pfam:SpoVA
LEPNOIND_02910 4e-184 spoVAD I Stage V sporulation protein AD
LEPNOIND_02911 2.2e-79 S Pfam:SpoVA
LEPNOIND_02912 4.8e-137 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEPNOIND_02913 4.3e-74 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LEPNOIND_02914 3.9e-54 spoIIAA T Belongs to the anti-sigma-factor antagonist family
LEPNOIND_02915 1.3e-215 dacF 3.4.16.4 M Belongs to the peptidase S11 family
LEPNOIND_02916 5.8e-143 3.5.1.104 G Polysaccharide deacetylase
LEPNOIND_02917 2.5e-83 yvsG S LexA-binding, inner membrane-associated putative hydrolase
LEPNOIND_02918 3.3e-56
LEPNOIND_02919 2.8e-20 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
LEPNOIND_02920 1.2e-242 emrB_1 EGP Major facilitator Superfamily
LEPNOIND_02921 2.5e-120 yocB J translation release factor activity
LEPNOIND_02922 1.8e-69 ohrB O Organic hydroperoxide resistance protein
LEPNOIND_02923 1e-235 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
LEPNOIND_02924 5.9e-227 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LEPNOIND_02925 1.9e-169 xerD L recombinase XerD
LEPNOIND_02926 9.6e-14 S Protein of unknown function (DUF4227)
LEPNOIND_02927 5e-87 fur P Belongs to the Fur family
LEPNOIND_02928 5.5e-102 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LEPNOIND_02929 1.8e-93 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
LEPNOIND_02931 1.2e-88 CO Thioredoxin-like
LEPNOIND_02932 1.8e-142 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LEPNOIND_02933 3.9e-212 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LEPNOIND_02934 6.9e-93 S UPF0316 protein
LEPNOIND_02935 7.8e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
LEPNOIND_02936 7e-98 yvbF K Belongs to the GbsR family
LEPNOIND_02937 6e-54 ybaZ 2.1.1.63 L Methyltransferase
LEPNOIND_02938 2.9e-84 V COG4767 Glycopeptide antibiotics resistance protein
LEPNOIND_02939 3.3e-188 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
LEPNOIND_02940 0.0 asnO 6.3.5.4 E Asparagine synthase
LEPNOIND_02941 1.3e-207 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEPNOIND_02942 4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEPNOIND_02943 1.1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEPNOIND_02944 3.3e-125 P Polycystin cation channel
LEPNOIND_02945 1.1e-248 lysC 2.7.2.4 E Belongs to the aspartokinase family
LEPNOIND_02947 2.5e-49
LEPNOIND_02948 3.4e-46 tnrA K transcriptional
LEPNOIND_02949 3.3e-149 yibQ S protein conserved in bacteria
LEPNOIND_02950 0.0 apr O Belongs to the peptidase S8 family
LEPNOIND_02951 5.5e-42
LEPNOIND_02952 2e-74 ykuL S CBS domain
LEPNOIND_02953 4.5e-82 3.6.1.55 S Pfam Polyketide cyclase dehydrase and lipid transport
LEPNOIND_02954 2.2e-70 yaaR S protein conserved in bacteria
LEPNOIND_02957 2e-200 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
LEPNOIND_02958 2e-73 5.1.99.1 E COG0346 Lactoylglutathione lyase and related lyases
LEPNOIND_02960 1.2e-94 yqjB S protein conserved in bacteria
LEPNOIND_02961 8.5e-171 yqjA S Putative aromatic acid exporter C-terminal domain
LEPNOIND_02962 2.4e-178 pilS 2.7.13.3 F GHKL domain
LEPNOIND_02963 1.9e-92 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEPNOIND_02964 3.1e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LEPNOIND_02965 2.3e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEPNOIND_02966 7.4e-30 K Cro/C1-type HTH DNA-binding domain
LEPNOIND_02967 1.8e-50 ansR K Helix-turn-helix XRE-family like proteins
LEPNOIND_02968 1.7e-30
LEPNOIND_02969 4.9e-139 yjcH P COG2382 Enterochelin esterase and related enzymes
LEPNOIND_02970 8.9e-95 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
LEPNOIND_02971 5.1e-78 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEPNOIND_02972 1.1e-195 dglA S Thiamine-binding protein
LEPNOIND_02973 4.2e-98
LEPNOIND_02974 1.1e-142 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEPNOIND_02975 2.9e-212 thiO 1.4.3.19 E Glycine oxidase
LEPNOIND_02976 4.8e-140 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LEPNOIND_02977 4e-27 thiS H ThiS family
LEPNOIND_02978 2e-109 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LEPNOIND_02979 2.5e-264 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
LEPNOIND_02980 2.4e-181 glcK 2.7.1.2 G Glucokinase
LEPNOIND_02981 3.1e-09 yqgQ S protein conserved in bacteria
LEPNOIND_02982 2e-83
LEPNOIND_02983 2.1e-67 yueI S Protein of unknown function (DUF1694)
LEPNOIND_02984 1.3e-268 spoVAF EG Bacillus/Clostridium GerA spore germination protein
LEPNOIND_02985 9.4e-297 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
LEPNOIND_02987 2.2e-241 nhaC C Na H antiporter
LEPNOIND_02988 9.3e-189 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LEPNOIND_02989 4e-142 S Integral membrane protein DUF92
LEPNOIND_02990 7.7e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEPNOIND_02991 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LEPNOIND_02992 2e-126 G PFAM Glycoside hydrolase 15-related
LEPNOIND_02993 3.7e-61
LEPNOIND_02994 9.1e-78 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEPNOIND_02995 0.0 mrdA 3.4.16.4 M penicillin-binding protein
LEPNOIND_02996 3.2e-234 yqgE EGP Major facilitator superfamily
LEPNOIND_02997 1.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
LEPNOIND_02998 8.4e-09
LEPNOIND_03003 2.1e-275 nptA P COG1283 Na phosphate symporter
LEPNOIND_03004 5.6e-197 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEPNOIND_03005 2.2e-117 O NfeD-like C-terminal, partner-binding
LEPNOIND_03006 4.7e-152 ypuA S Secreted protein
LEPNOIND_03007 1.7e-186 EGP Major facilitator Superfamily
LEPNOIND_03008 3.4e-61 fimV NU translation initiation factor activity
LEPNOIND_03009 1.2e-200 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LEPNOIND_03010 6.4e-67 yqfX S membrane
LEPNOIND_03011 2e-111 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
LEPNOIND_03012 7.4e-38 S Domain of Unknown Function (DUF1540)
LEPNOIND_03013 1.4e-77 zur P Belongs to the Fur family
LEPNOIND_03014 4e-140 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LEPNOIND_03015 1.1e-144 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LEPNOIND_03016 2.2e-131 GH23 M Transglycosylase SLT domain
LEPNOIND_03017 2.5e-214 pilS 2.7.13.3 T His Kinase A (phosphoacceptor) domain
LEPNOIND_03018 1.1e-08 yqfT S Protein of unknown function (DUF2624)
LEPNOIND_03019 8.1e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LEPNOIND_03020 8e-252 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEPNOIND_03021 4.2e-49 yqfQ S YqfQ-like protein
LEPNOIND_03022 1.4e-84 carD K Transcription factor
LEPNOIND_03023 1.4e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LEPNOIND_03024 1.9e-195 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEPNOIND_03025 6.2e-140 trmK 2.1.1.217 S SAM-dependent methyltransferase
LEPNOIND_03026 6e-64 C COG2010 Cytochrome c, mono- and diheme variants
LEPNOIND_03027 1.9e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEPNOIND_03028 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEPNOIND_03029 9.5e-80 yaiI S Belongs to the UPF0178 family
LEPNOIND_03030 1.6e-143 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEPNOIND_03031 2.6e-112 ccpN K CBS domain
LEPNOIND_03032 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LEPNOIND_03033 2.4e-172 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LEPNOIND_03035 1.3e-142 recO L Involved in DNA repair and RecF pathway recombination
LEPNOIND_03036 1.6e-17 S YqzL-like protein
LEPNOIND_03037 1.6e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEPNOIND_03038 1e-72 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LEPNOIND_03039 1.3e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LEPNOIND_03040 5.1e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEPNOIND_03041 0.0 yqfF S membrane-associated HD superfamily hydrolase
LEPNOIND_03042 6.8e-173 phoH T Phosphate starvation-inducible protein PhoH
LEPNOIND_03043 1.2e-222 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
LEPNOIND_03044 1.8e-47 yqfC S sporulation protein YqfC
LEPNOIND_03045 1.6e-73
LEPNOIND_03046 3.4e-98 yqfA S UPF0365 protein
LEPNOIND_03047 7.8e-223 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
LEPNOIND_03048 9.4e-56 yqeY S Yqey-like protein
LEPNOIND_03049 2.1e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LEPNOIND_03050 6.4e-160 yqeW P COG1283 Na phosphate symporter
LEPNOIND_03051 1.3e-176 iolS C Aldo keto reductase
LEPNOIND_03052 1.3e-114 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LEPNOIND_03053 7.4e-220 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEPNOIND_03054 9.6e-138 ycgJ_1 Q ubiE/COQ5 methyltransferase family
LEPNOIND_03055 3.8e-254 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
LEPNOIND_03056 1.3e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LEPNOIND_03057 9.3e-175 prmA J Methylates ribosomal protein L11
LEPNOIND_03058 4.3e-195 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEPNOIND_03059 9.9e-298 dnaK O Heat shock 70 kDa protein
LEPNOIND_03060 1.4e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEPNOIND_03061 1.2e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEPNOIND_03062 1.6e-221 hemN H Involved in the biosynthesis of porphyrin-containing compound
LEPNOIND_03063 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEPNOIND_03064 4.3e-53
LEPNOIND_03065 5.3e-204 spoIIP M stage II sporulation protein P
LEPNOIND_03066 8.4e-207 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LEPNOIND_03067 4.8e-36 rpsT J Binds directly to 16S ribosomal RNA
LEPNOIND_03068 4.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
LEPNOIND_03069 2.4e-07 S YqzM-like protein
LEPNOIND_03070 0.0 comEC S Competence protein ComEC
LEPNOIND_03071 2.5e-109 comEB 3.5.4.12 F ComE operon protein 2
LEPNOIND_03072 1.9e-107 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
LEPNOIND_03073 7.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEPNOIND_03074 5.3e-141 cmoA S Methyltransferase domain
LEPNOIND_03075 6.7e-164 cvfB S protein conserved in bacteria
LEPNOIND_03076 9.8e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEPNOIND_03077 3.6e-108 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LEPNOIND_03078 2.3e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEPNOIND_03079 3e-47 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
LEPNOIND_03080 3.6e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEPNOIND_03081 1.8e-217 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LEPNOIND_03082 6.2e-96 yqeG S hydrolase of the HAD superfamily
LEPNOIND_03084 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LEPNOIND_03085 8.1e-73 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEPNOIND_03086 5.2e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEPNOIND_03087 3.9e-268 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEPNOIND_03088 2.8e-82 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEPNOIND_03089 3.1e-38 phaF P Multiple resistance and pH regulation protein F (MrpF / PhaF)
LEPNOIND_03090 6.4e-67 phaG P Na+/H+ antiporter subunit
LEPNOIND_03091 1.4e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEPNOIND_03092 4.4e-152 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEPNOIND_03094 2e-260 M Belongs to the BCCT transporter (TC 2.A.15) family
LEPNOIND_03095 1.3e-221 nasA P COG2223 Nitrate nitrite transporter
LEPNOIND_03096 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEPNOIND_03097 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LEPNOIND_03098 2.3e-56 nirD 1.7.1.15 P Nitrite reductase
LEPNOIND_03099 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LEPNOIND_03100 1.9e-253 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LEPNOIND_03102 4.3e-93 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
LEPNOIND_03103 1.2e-185 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_03104 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEPNOIND_03105 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEPNOIND_03106 1.1e-09 yaaB S Domain of unknown function (DUF370)
LEPNOIND_03107 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEPNOIND_03108 9.1e-33 yaaA S S4 domain
LEPNOIND_03109 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEPNOIND_03110 1.3e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEPNOIND_03111 1.9e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
LEPNOIND_03112 6e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEPNOIND_03113 3.9e-127 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEPNOIND_03114 2.6e-112 jag S single-stranded nucleic acid binding R3H
LEPNOIND_03116 3.2e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEPNOIND_03117 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEPNOIND_03118 5.8e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LEPNOIND_03119 7.9e-149 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LEPNOIND_03120 2e-135 soj D COG1192 ATPases involved in chromosome partitioning
LEPNOIND_03121 9.2e-153 spo0J K Belongs to the ParB family
LEPNOIND_03122 3.7e-218 sufS 2.8.1.7, 4.4.1.16 E Aminotransferase class-V
LEPNOIND_03123 1.1e-115 yyaC S Sporulation protein YyaC
LEPNOIND_03124 7.6e-175 yyaD S Membrane
LEPNOIND_03125 1.8e-27 yyzM S protein conserved in bacteria
LEPNOIND_03126 1e-193 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEPNOIND_03127 6.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
LEPNOIND_03128 1.6e-58 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEPNOIND_03129 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEPNOIND_03130 1.7e-149 yybS S membrane
LEPNOIND_03131 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LEPNOIND_03132 7.7e-55 rplI J binds to the 23S rRNA
LEPNOIND_03133 6.7e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LEPNOIND_03134 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEPNOIND_03140 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_03141 0.0 vicK 2.7.13.3 T Histidine kinase
LEPNOIND_03142 1e-251 yycH S protein conserved in bacteria
LEPNOIND_03143 2.9e-157 yycI S protein conserved in bacteria
LEPNOIND_03144 1.1e-147 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LEPNOIND_03145 5e-197 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEPNOIND_03146 7.1e-08 S YyzF-like protein
LEPNOIND_03147 7e-78 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEPNOIND_03148 1e-252 L Dead deah box helicase domain protein
LEPNOIND_03149 5.7e-89 S Domain of unknown function (DUF1837)
LEPNOIND_03150 6.8e-26 M COG3209 Rhs family protein
LEPNOIND_03151 8.6e-251 S Putative nucleotide-binding of sugar-metabolising enzyme
LEPNOIND_03152 5.3e-110 K FCD domain
LEPNOIND_03153 3.5e-191 1.1.1.14 E Dehydrogenase
LEPNOIND_03154 6.7e-184 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LEPNOIND_03155 5e-74 siaT_3 G Tripartite ATP-independent periplasmic transporters, DctQ component
LEPNOIND_03156 3.2e-210 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
LEPNOIND_03157 2e-123 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
LEPNOIND_03158 0.0 pspF K PTS system fructose IIA component
LEPNOIND_03159 8.8e-201 M SIS domain
LEPNOIND_03160 6.9e-137 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
LEPNOIND_03161 1.5e-101 G PTS system sorbose-specific iic component
LEPNOIND_03162 2.6e-80 2.7.1.191 G PTS system mannose fructose sorbose family
LEPNOIND_03163 1.4e-71 2.7.1.191 G PTS system fructose IIA component
LEPNOIND_03164 4.5e-152 V ABC transporter
LEPNOIND_03165 4.6e-112 S ABC-2 family transporter protein
LEPNOIND_03168 1.5e-133 Z012_10580 S Sulfite exporter TauE/SafE
LEPNOIND_03170 0.0 oppA5 E Bacterial extracellular solute-binding proteins, family 5 Middle
LEPNOIND_03171 1.5e-172 appB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_03172 4.1e-167 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_03173 1.1e-181 oppD3 P Belongs to the ABC transporter superfamily
LEPNOIND_03174 2.7e-185 oppF3 E Belongs to the ABC transporter superfamily
LEPNOIND_03175 9.8e-189 S domain protein
LEPNOIND_03176 0.0 ydfJ S MMPL family
LEPNOIND_03177 1.6e-105 K Transcriptional regulator
LEPNOIND_03178 0.0 lytS 2.7.13.3 T Histidine kinase
LEPNOIND_03179 3.6e-134 T COG3279 Response regulator of the LytR AlgR family
LEPNOIND_03180 4.5e-269 cstA T Carbon starvation protein
LEPNOIND_03181 2.8e-84
LEPNOIND_03183 8.5e-116 S CGNR zinc finger
LEPNOIND_03184 3.8e-75 S Domain of unknown function (DU1801)
LEPNOIND_03185 1.1e-184 S Domain of unknown function (DUF4179)
LEPNOIND_03186 9.9e-97 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LEPNOIND_03187 1.1e-89 paiA K Acetyltransferase (GNAT) domain
LEPNOIND_03188 3e-263 NT chemotaxis protein
LEPNOIND_03189 1.5e-194 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
LEPNOIND_03190 1.6e-115 K FCD
LEPNOIND_03191 3.1e-184 G Bacterial extracellular solute-binding protein, family 7
LEPNOIND_03192 1.3e-76 G Tripartite ATP-independent periplasmic transporters, DctQ component
LEPNOIND_03193 9.2e-210 siaM G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
LEPNOIND_03194 4.6e-202 citA 2.3.3.1 C Belongs to the citrate synthase family
LEPNOIND_03195 1.9e-161 K Transcriptional regulator
LEPNOIND_03196 1.2e-185 S NMT1-like family
LEPNOIND_03197 0.0 S Tripartite ATP-independent periplasmic transporter, DctM component
LEPNOIND_03198 7.6e-121 K FCD
LEPNOIND_03199 1.1e-122 K COG2186 Transcriptional regulators
LEPNOIND_03200 2.6e-266 glcD 1.1.3.15 C Glycolate oxidase subunit
LEPNOIND_03201 3.3e-222 glcF C Glycolate oxidase
LEPNOIND_03202 2e-227 lhgO 1.1.99.2 S FAD dependent oxidoreductase
LEPNOIND_03203 8.4e-301 QT COG2508 Regulator of polyketide synthase expression
LEPNOIND_03205 1.1e-223 codB F cytosine purines uracil thiamine allantoin
LEPNOIND_03206 2.3e-245 codA 3.5.4.1 F Amidohydrolase family
LEPNOIND_03208 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
LEPNOIND_03209 7.6e-244 G COG2182 Maltose-binding periplasmic proteins domains
LEPNOIND_03210 2.1e-249 malC P COG1175 ABC-type sugar transport systems, permease components
LEPNOIND_03211 3.5e-149 malG P transport
LEPNOIND_03212 2.8e-188 malR 5.1.1.1 K Transcriptional regulator
LEPNOIND_03213 1.2e-241 atoE I Short chain fatty acid transporter
LEPNOIND_03214 5.6e-132 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LEPNOIND_03215 2.8e-114 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LEPNOIND_03216 0.0 ubiD 4.1.1.98 H Belongs to the UbiD family
LEPNOIND_03217 6.9e-189 mhqA E COG0346 Lactoylglutathione lyase and related lyases
LEPNOIND_03218 1.4e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
LEPNOIND_03219 2.2e-229 yciC S GTPases (G3E family)
LEPNOIND_03220 2.5e-40 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEPNOIND_03221 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEPNOIND_03222 7.9e-149 degV S protein conserved in bacteria
LEPNOIND_03223 2e-109 S DUF218 domain
LEPNOIND_03225 2.8e-57 K Transcriptional regulator
LEPNOIND_03226 9.9e-118 M1-1017 S Protein of unknown function (DUF1129)
LEPNOIND_03227 2.3e-09
LEPNOIND_03228 7e-33
LEPNOIND_03230 4.4e-195 P COG2807 Cyanate permease
LEPNOIND_03231 2.1e-177 S amine dehydrogenase activity
LEPNOIND_03232 2.3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_03233 2.4e-259 T Histidine kinase
LEPNOIND_03234 4.4e-71 S YtkA-like
LEPNOIND_03235 2.3e-66 eaeH M LysM domain
LEPNOIND_03236 3.1e-46 phhB 3.5.4.33, 4.2.1.96 H pterin-4-alpha-carbinolamine dehydratase
LEPNOIND_03237 3.4e-239 S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LEPNOIND_03238 5.2e-147 ubiE Q Methyltransferase type 11
LEPNOIND_03239 3.2e-106 GBS0088 S protein conserved in bacteria
LEPNOIND_03240 4.5e-225 EGP Major facilitator Superfamily
LEPNOIND_03241 1.6e-79 sdpI S integral membrane protein
LEPNOIND_03242 2e-236 braB E Component of the transport system for branched-chain amino acids
LEPNOIND_03243 2e-61 S CHY zinc finger
LEPNOIND_03244 1.7e-176 rihB 3.2.2.1 F nucleoside hydrolase
LEPNOIND_03245 9.2e-118 idi I COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LEPNOIND_03246 6.2e-304 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LEPNOIND_03247 3e-122 T COG4565 Response regulator of citrate malate metabolism
LEPNOIND_03248 1.6e-307 sdcS P Sodium:sulfate symporter transmembrane region
LEPNOIND_03249 9.3e-121 lolD V ABC transporter
LEPNOIND_03250 0.0
LEPNOIND_03252 0.0 2.7.13.3 T Histidine kinase
LEPNOIND_03254 5.7e-200 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LEPNOIND_03255 2.6e-140 S GNAT acetyltransferase
LEPNOIND_03256 3.9e-69
LEPNOIND_03257 4.1e-68
LEPNOIND_03258 0.0
LEPNOIND_03259 4e-124
LEPNOIND_03260 4.8e-125
LEPNOIND_03261 2.2e-125
LEPNOIND_03262 5.2e-75 yosT L Bacterial transcription activator, effector binding domain
LEPNOIND_03263 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEPNOIND_03264 1.9e-89 K GrpB protein
LEPNOIND_03265 4.8e-176 O Predicted Zn-dependent protease (DUF2268)
LEPNOIND_03266 2e-143 mta K TipAS antibiotic-recognition domain
LEPNOIND_03268 1.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LEPNOIND_03269 1e-111 yrbG3 S membrane
LEPNOIND_03270 2.2e-108 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LEPNOIND_03271 3.5e-174 murB 1.3.1.98 M cell wall formation
LEPNOIND_03272 0.0 ywjA V ABC transporter
LEPNOIND_03273 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LEPNOIND_03274 7e-98 S DinB superfamily
LEPNOIND_03275 1.8e-215 yxlH EGP Major facilitator Superfamily
LEPNOIND_03276 0.0 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEPNOIND_03277 8.1e-205 NT chemotaxis protein
LEPNOIND_03278 1.3e-226 S Acetyltransferase
LEPNOIND_03279 1.7e-254 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
LEPNOIND_03280 5.3e-147 ycsE 3.1.3.104 S hydrolases of the HAD superfamily
LEPNOIND_03281 3.2e-175 troA P Belongs to the bacterial solute-binding protein 9 family
LEPNOIND_03282 3.2e-141 troB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LEPNOIND_03283 2.2e-160 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LEPNOIND_03284 2.3e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
LEPNOIND_03285 7.5e-100 S UPF0302 domain
LEPNOIND_03286 6e-55 yflT S Heat induced stress protein YflT
LEPNOIND_03287 2.6e-43 ydzA EGP Major facilitator Superfamily
LEPNOIND_03288 1.5e-230 ywbD 2.1.1.191 J Methyltransferase
LEPNOIND_03289 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEPNOIND_03290 4.3e-250 3.1.3.1 P Belongs to the alkaline phosphatase family
LEPNOIND_03291 5.7e-120 ydbC G Domain of unknown function (DUF4937
LEPNOIND_03292 2.3e-136 map 3.4.11.18 E Methionine aminopeptidase
LEPNOIND_03293 1.5e-155 yuaG 3.4.21.72 S protein conserved in bacteria
LEPNOIND_03294 1.7e-82 yuaF OU Membrane protein implicated in regulation of membrane protease activity
LEPNOIND_03296 1.3e-290 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LEPNOIND_03297 1.9e-71 bdbC O Required for disulfide bond formation in some proteins
LEPNOIND_03298 3.2e-75 bdbA CO Thioredoxin
LEPNOIND_03299 2.7e-261 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEPNOIND_03300 1.3e-87 K Acetyltransferase (GNAT) domain
LEPNOIND_03301 2.6e-77 S Protein of unknown function (DUF4064)
LEPNOIND_03302 9e-264 6.3.1.2 E Glutamine synthetase, catalytic domain
LEPNOIND_03303 7.9e-193 I Fatty acid desaturase
LEPNOIND_03304 7.1e-236 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E methionine gamma-lyase
LEPNOIND_03305 2.4e-130 S B3/4 domain
LEPNOIND_03306 4.1e-278 gntR9 K Alanine-glyoxylate amino-transferase
LEPNOIND_03307 3.4e-124 azlC E AzlC protein
LEPNOIND_03308 3.4e-47 S Branched-chain amino acid transport protein (AzlD)
LEPNOIND_03309 1.4e-278 hutH 4.3.1.3 E Histidine ammonia-lyase
LEPNOIND_03310 8.9e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEPNOIND_03311 1.7e-233 BH2250 S protein conserved in bacteria
LEPNOIND_03312 3e-138 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEPNOIND_03313 1.4e-179 abrB S Pfam:AmoA
LEPNOIND_03314 1.3e-229 amtB P Ammonium transporter
LEPNOIND_03315 6.1e-171 2.7.7.7 T Putative nucleotidyltransferase substrate binding domain
LEPNOIND_03316 3.2e-135 dnaQ2 2.7.7.7 L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
LEPNOIND_03317 5.2e-47 S Family of unknown function (DUF5327)
LEPNOIND_03318 8.4e-271 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEPNOIND_03319 2.5e-112 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEPNOIND_03320 1.3e-58 ywdK S small membrane protein
LEPNOIND_03321 6.1e-79 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LEPNOIND_03322 1.3e-78 cwlJ 3.5.1.28 M Cell wall
LEPNOIND_03323 8.4e-131
LEPNOIND_03324 1.2e-62 K helix_turn_helix gluconate operon transcriptional repressor
LEPNOIND_03325 1.4e-161 natA1 V ABC transporter
LEPNOIND_03326 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
LEPNOIND_03327 1.3e-184 yhaP CP COG1668 ABC-type Na efflux pump, permease component
LEPNOIND_03328 5.8e-48
LEPNOIND_03329 2e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEPNOIND_03330 1.2e-145 ywfI C May function as heme-dependent peroxidase
LEPNOIND_03331 3e-142 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
LEPNOIND_03332 2.9e-182 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
LEPNOIND_03333 4.8e-151 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LEPNOIND_03334 2.1e-198 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEPNOIND_03335 3.4e-252 ywfO S COG1078 HD superfamily phosphohydrolases
LEPNOIND_03336 1.5e-91 ywgA 2.1.1.72, 3.1.21.3
LEPNOIND_03338 5.6e-26 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
LEPNOIND_03339 6.4e-125 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LEPNOIND_03340 9.4e-198 F S-adenosylhomocysteine deaminase activity
LEPNOIND_03341 2.4e-98 ywhD S YwhD family
LEPNOIND_03342 0.0 pepF E oligoendopeptidase F
LEPNOIND_03343 1.7e-156 vipF 2.3.1.128 K Acetyltransferase (GNAT) domain
LEPNOIND_03344 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEPNOIND_03345 4.8e-159 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LEPNOIND_03346 6e-168 speB 3.5.3.11 E Belongs to the arginase family
LEPNOIND_03347 1e-75 ywiB S protein conserved in bacteria
LEPNOIND_03348 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LEPNOIND_03349 2.3e-73 yqgC S protein conserved in bacteria
LEPNOIND_03350 2.8e-224 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LEPNOIND_03351 0.0 fadF C COG0247 Fe-S oxidoreductase
LEPNOIND_03352 2.7e-216 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
LEPNOIND_03353 3.3e-155 hbdA 1.1.1.157 I Dehydrogenase
LEPNOIND_03354 2.9e-207 mmgC I acyl-CoA dehydrogenase
LEPNOIND_03355 1.7e-108 kstR2_2 K Transcriptional regulator
LEPNOIND_03356 6.1e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEPNOIND_03357 2.2e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEPNOIND_03358 5.4e-92 ywjG S Domain of unknown function (DUF2529)
LEPNOIND_03359 2.5e-59 spo0F T response regulator
LEPNOIND_03360 2.7e-160 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
LEPNOIND_03361 1.7e-114 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LEPNOIND_03362 3.5e-209 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEPNOIND_03363 7e-178 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
LEPNOIND_03364 1.3e-235 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEPNOIND_03365 3.8e-40 rpmE2 J Ribosomal protein L31
LEPNOIND_03366 2.9e-110 tdk 2.7.1.21 F thymidine kinase
LEPNOIND_03367 1.9e-74
LEPNOIND_03368 1.7e-259 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEPNOIND_03369 8.6e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEPNOIND_03370 7.8e-160 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEPNOIND_03371 1.4e-113 spoIIR S stage II sporulation protein R
LEPNOIND_03372 4.4e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
LEPNOIND_03373 2.3e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEPNOIND_03374 1.6e-61 S Regulator of ribonuclease activity B
LEPNOIND_03375 8.7e-93 mntP P Probably functions as a manganese efflux pump
LEPNOIND_03376 1e-72 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEPNOIND_03377 7.6e-151 mcpA NT Chemotaxis
LEPNOIND_03378 4.9e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
LEPNOIND_03379 5.9e-97 ywlG S Belongs to the UPF0340 family
LEPNOIND_03380 6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEPNOIND_03381 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEPNOIND_03382 4.6e-90 panZ K -acetyltransferase
LEPNOIND_03383 0.0 vpr O Belongs to the peptidase S8 family
LEPNOIND_03384 1.4e-23 atpI S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
LEPNOIND_03385 7.3e-12 S ATP synthase I chain
LEPNOIND_03386 2.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
LEPNOIND_03387 1.4e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEPNOIND_03388 1.3e-31 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEPNOIND_03389 6.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEPNOIND_03390 1.7e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEPNOIND_03391 9.2e-153 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEPNOIND_03392 4.2e-264 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEPNOIND_03393 7e-55 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LEPNOIND_03394 1.5e-21 ywmB S TATA-box binding
LEPNOIND_03395 3.8e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEPNOIND_03396 4.3e-189 spoIID D Stage II sporulation protein D
LEPNOIND_03397 3.4e-131 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
LEPNOIND_03398 1.1e-53 sugE P Multidrug resistance protein
LEPNOIND_03399 1.9e-47 ykkD P Multidrug resistance protein
LEPNOIND_03400 3.6e-45 spoIIID K Stage III sporulation protein D
LEPNOIND_03401 1.6e-180 mbl D Rod shape-determining protein
LEPNOIND_03402 1.5e-141 flhO N flagellar basal body
LEPNOIND_03403 8.7e-142 flhP N flagellar basal body
LEPNOIND_03404 1.2e-61 epuA S DNA-directed RNA polymerase subunit beta
LEPNOIND_03405 1.3e-274 P Spore gernimation protein GerA
LEPNOIND_03406 2.7e-197 E Spore germination protein
LEPNOIND_03407 1.4e-195 S Spore germination B3/ GerAC like, C-terminal
LEPNOIND_03408 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEPNOIND_03409 6.6e-147 estA S Putative esterase
LEPNOIND_03410 2.7e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEPNOIND_03411 4.7e-272 pip S YhgE Pip N-terminal domain protein
LEPNOIND_03412 1.7e-96 speG_2 2.3.1.57 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LEPNOIND_03413 2.5e-86 yisT S DinB family
LEPNOIND_03414 2.8e-151 Q N-acetyltransferase
LEPNOIND_03415 2e-225 lytE M NlpC/P60 family
LEPNOIND_03416 1.5e-241 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEPNOIND_03417 1.4e-231
LEPNOIND_03418 9e-46 HA62_12640 S GCN5-related N-acetyl-transferase
LEPNOIND_03419 6.9e-167 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LEPNOIND_03420 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LEPNOIND_03421 2.8e-227 rodA D Belongs to the SEDS family
LEPNOIND_03422 3.8e-78 FG Scavenger mRNA decapping enzyme C-term binding
LEPNOIND_03423 2.4e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
LEPNOIND_03424 3.3e-83 S Tetratrico peptide repeat
LEPNOIND_03425 1.6e-171 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LEPNOIND_03426 1.1e-116 ywqC M biosynthesis protein
LEPNOIND_03427 2.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
LEPNOIND_03428 4.2e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
LEPNOIND_03429 1.9e-72 S An automated process has identified a potential problem with this gene model
LEPNOIND_03430 4.5e-130 S Protein of unknown function (DUF3100)
LEPNOIND_03431 1e-156 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LEPNOIND_03432 4.3e-272 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEPNOIND_03433 4.1e-289 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 T Domain present in phytochromes and cGMP-specific phosphodiesterases.
LEPNOIND_03434 1.6e-165 S Tetratricopeptide repeat
LEPNOIND_03437 4.8e-07
LEPNOIND_03438 2.8e-07
LEPNOIND_03441 4.3e-277 S LXG domain of WXG superfamily
LEPNOIND_03444 4e-65 ytcD5 K Transcriptional regulator
LEPNOIND_03445 6.4e-104 1.6.5.2 S NADPH-dependent FMN reductase
LEPNOIND_03446 5.2e-110 K intracellular protease amidase
LEPNOIND_03448 7.9e-30 S Domain of unknown function (DUF3784)
LEPNOIND_03449 4.3e-32 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEPNOIND_03450 2e-40 exoZ I Acyltransferase family
LEPNOIND_03451 5.5e-150 rfbD 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEPNOIND_03452 1.1e-197 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEPNOIND_03453 2.7e-102 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LEPNOIND_03454 3.6e-168 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEPNOIND_03455 1e-138 rgpAc GT4 M Domain of unknown function (DUF1972)
LEPNOIND_03456 3.4e-57 M Psort location CytoplasmicMembrane, score 7.88
LEPNOIND_03457 1e-122 wcoF M Glycosyltransferase Family 4
LEPNOIND_03458 7.1e-37 GT2 V Glycosyl transferase, family 2
LEPNOIND_03460 5.3e-23 S Glycosyl transferase family 2
LEPNOIND_03461 8e-41 wzx S Polysaccharide biosynthesis protein
LEPNOIND_03462 3.1e-87 cpsE M Bacterial sugar transferase
LEPNOIND_03463 1.5e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEPNOIND_03464 1.4e-148 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LEPNOIND_03467 3.7e-199 S response regulator aspartate phosphatase
LEPNOIND_03468 1.8e-212 gerAC S Spore germination B3/ GerAC like, C-terminal
LEPNOIND_03469 1.5e-192 gerAB E Spore germination protein
LEPNOIND_03470 1.9e-248 gerAA EG Spore germination protein
LEPNOIND_03471 2.6e-202 C NADH:flavin oxidoreductase / NADH oxidase family
LEPNOIND_03472 1.5e-101 K Bacterial regulatory proteins, tetR family
LEPNOIND_03473 6.7e-81 S Bacterial PH domain
LEPNOIND_03474 3.4e-132 IQ Short-chain dehydrogenase reductase sdr
LEPNOIND_03475 3.6e-266 alsT E Sodium alanine symporter
LEPNOIND_03476 6.4e-122 mdmC 2.1.1.104 S O-methyltransferase
LEPNOIND_03477 2.4e-164 K LysR substrate binding domain
LEPNOIND_03478 9.9e-45 sdpR K transcriptional
LEPNOIND_03479 8.1e-114 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LEPNOIND_03480 4.8e-143 MA20_35565 4.1.3.30 G Phosphoenolpyruvate phosphomutase
LEPNOIND_03481 1.6e-162 E Glyoxalase-like domain
LEPNOIND_03482 8e-185 P ABC transporter substrate-binding protein
LEPNOIND_03483 5.1e-139 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEPNOIND_03484 6.1e-129 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
LEPNOIND_03486 1.2e-117 yoaZ 3.5.1.124 S DJ-1/PfpI family
LEPNOIND_03487 2.6e-156 yobV9 K transcriptional regulator
LEPNOIND_03488 2.8e-151 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LEPNOIND_03489 3e-95 2.3.1.59 K Acetyltransferase (GNAT) domain
LEPNOIND_03490 1e-139 S Alpha/beta hydrolase family
LEPNOIND_03491 5.5e-102 4.2.1.46, 5.1.3.2 GM NAD dependent epimerase/dehydratase family
LEPNOIND_03493 0.0 otrA J Elongation factor G, domain IV
LEPNOIND_03495 2.4e-231 S Putative esterase
LEPNOIND_03496 3.5e-91 yvdQ S Protein of unknown function (DUF3231)
LEPNOIND_03497 9.5e-46 ycbP S Protein of unknown function (DUF2512)
LEPNOIND_03498 7.9e-145 yqjF S Uncharacterized conserved protein (COG2071)
LEPNOIND_03500 2.3e-215 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
LEPNOIND_03501 6e-260 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LEPNOIND_03502 2e-253 S Membrane
LEPNOIND_03503 1e-59 pucM 3.5.2.17 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
LEPNOIND_03504 1.1e-183 uox 1.7.3.3, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
LEPNOIND_03505 1e-90 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 S OHCU decarboxylase
LEPNOIND_03506 6.6e-309 pucR QT COG2508 Regulator of polyketide synthase expression
LEPNOIND_03507 1.8e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LEPNOIND_03508 2.3e-242 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LEPNOIND_03509 3.7e-91 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LEPNOIND_03510 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LEPNOIND_03511 1.4e-164 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LEPNOIND_03512 1.7e-105 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
LEPNOIND_03513 2.8e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LEPNOIND_03514 9.3e-186 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LEPNOIND_03515 6.4e-146 MA20_40340 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_03516 8.2e-140 P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LEPNOIND_03517 3.3e-189 P NMT1-like family
LEPNOIND_03518 2.7e-144 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_03519 4.3e-138 P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LEPNOIND_03520 0.0 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPNOIND_03521 5.5e-186 cbrA5 P Ferrichrome ABC transporter substrate-binding protein
LEPNOIND_03522 2e-70 hit FG Scavenger mRNA decapping enzyme C-term binding
LEPNOIND_03523 7.7e-82 nsrR K Transcriptional regulator
LEPNOIND_03524 1.2e-82 6.3.3.2 S ASCH
LEPNOIND_03525 0.0 uidA G Belongs to the glycosyl hydrolase 2 family
LEPNOIND_03526 1.1e-153 fldX 1.1.1.31 I Domain of unknown function (DUF1932)
LEPNOIND_03527 2.2e-154 K Helix-turn-helix domain, rpiR family
LEPNOIND_03528 1.7e-116 H Methyltransferase
LEPNOIND_03529 8.3e-32
LEPNOIND_03530 1.1e-242 G Tripartite ATP-independent periplasmic transporter, DctM component
LEPNOIND_03531 3.9e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPNOIND_03532 7.7e-182 K Transcriptional regulator
LEPNOIND_03533 1.4e-256 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEPNOIND_03534 9.8e-304 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
LEPNOIND_03535 9e-184 scrR K helix_turn _helix lactose operon repressor
LEPNOIND_03536 1.9e-115 drgA C nitroreductase
LEPNOIND_03537 1.7e-60 K helix_turn_helix, mercury resistance
LEPNOIND_03538 4.8e-137 ycsF S Belongs to the UPF0271 (lamB) family
LEPNOIND_03539 3e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
LEPNOIND_03540 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
LEPNOIND_03541 2.2e-139 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
LEPNOIND_03542 3e-264 G Bacterial extracellular solute-binding protein
LEPNOIND_03543 1.6e-171 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_03544 1.6e-160 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_03545 2.2e-139 K helix_turn_helix, mercury resistance
LEPNOIND_03546 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LEPNOIND_03547 6.6e-82
LEPNOIND_03548 5.8e-255 gltD 1.3.1.1 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LEPNOIND_03549 2.9e-232 preA 1.3.1.1 CF dihydroorotate dehydrogenase
LEPNOIND_03550 4.1e-275 hyuA 3.5.2.2 F Amidohydrolase family
LEPNOIND_03551 2.6e-07
LEPNOIND_03552 1.7e-237 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LEPNOIND_03553 1.1e-261 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEPNOIND_03554 4e-77 F PFAM AIG2 family protein
LEPNOIND_03555 7.4e-115 ywnB S NAD(P)H-binding
LEPNOIND_03556 5.7e-71 ywnA K Transcriptional regulator
LEPNOIND_03558 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEPNOIND_03559 6e-67 licT K transcriptional antiterminator
LEPNOIND_03560 1.5e-70 licT K transcriptional antiterminator
LEPNOIND_03561 2.5e-288 bglH7 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEPNOIND_03562 3.2e-56 L Transposase and inactivated derivatives
LEPNOIND_03563 2.1e-68 L transposase activity
LEPNOIND_03564 4e-53
LEPNOIND_03565 2.9e-75 S Protein of unknown function, DUF600
LEPNOIND_03566 1.8e-80 S SMI1-KNR4 cell-wall
LEPNOIND_03567 8.2e-37
LEPNOIND_03568 1.6e-93
LEPNOIND_03569 7.5e-76 S Immunity protein 70
LEPNOIND_03570 3.3e-119 U Belongs to the WXG100 family
LEPNOIND_03571 5.8e-61
LEPNOIND_03572 6.2e-54
LEPNOIND_03573 0.0 M nuclease activity
LEPNOIND_03574 4.6e-39 S Family of unknown function (DUF5344)
LEPNOIND_03575 1.6e-24 S Domain of unknown function (DUF5082)
LEPNOIND_03576 1.1e-147 yjqC P Catalase
LEPNOIND_03577 3.8e-108 E Lysine exporter protein LysE YggA
LEPNOIND_03578 2.3e-243 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
LEPNOIND_03579 2.5e-115 yhcQ M Spore coat protein
LEPNOIND_03581 3.3e-167 eutC 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
LEPNOIND_03582 1.7e-168 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
LEPNOIND_03583 4.2e-207 mntH P H( )-stimulated, divalent metal cation uptake system
LEPNOIND_03584 2.4e-113 S HTH domain
LEPNOIND_03585 1.1e-188 speB 3.5.3.11 E Arginase family
LEPNOIND_03586 1.1e-127 T Transcriptional regulator
LEPNOIND_03587 1.5e-203 T PhoQ Sensor
LEPNOIND_03588 2.2e-165 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
LEPNOIND_03589 4.2e-124 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
LEPNOIND_03590 7.6e-117 ydfE S Flavin reductase like domain
LEPNOIND_03591 8.1e-115 S ABC-2 family transporter protein
LEPNOIND_03592 8.3e-168 ycbN V ABC transporter, ATP-binding protein
LEPNOIND_03593 5.1e-165 T PhoQ Sensor
LEPNOIND_03594 1.2e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_03595 0.0 M Domain of unknown function DUF11
LEPNOIND_03596 1.5e-100 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LEPNOIND_03597 9.6e-32 S Sporulation inhibitor A
LEPNOIND_03598 6.6e-158 chiA 3.2.1.14, 3.2.1.17 AA10,CBM15,CBM73,GH18 D Lytic polysaccharide mono-oxygenase, cellulose-degrading
LEPNOIND_03599 1.7e-142 C KR domain
LEPNOIND_03600 1.3e-55 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
LEPNOIND_03601 1.4e-176 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
LEPNOIND_03602 4.3e-98 srlA G PTS system enzyme II sorbitol-specific factor
LEPNOIND_03603 8.9e-75 gutM K Glucitol operon activator
LEPNOIND_03604 9.1e-173 sorC K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LEPNOIND_03605 2e-288 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
LEPNOIND_03606 8.4e-287 uxaA 4.2.1.7 G Altronate
LEPNOIND_03607 9.8e-252 yteT S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_03608 5.1e-125 S Integral membrane protein
LEPNOIND_03609 2.6e-83 G carbohydrate transport
LEPNOIND_03610 3.7e-223 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
LEPNOIND_03611 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
LEPNOIND_03612 1.5e-169 E Abhydrolase family
LEPNOIND_03613 1.2e-155 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_03614 5.7e-180 G COG4209 ABC-type polysaccharide transport system, permease component
LEPNOIND_03615 8.2e-298 G ABC transporter substrate-binding protein
LEPNOIND_03616 0.0 K Transcriptional regulator
LEPNOIND_03617 7.1e-161 3.2.2.21 K AraC-like ligand binding domain
LEPNOIND_03618 1.8e-200 pelE 3.4.11.10, 3.4.11.6, 4.2.2.2 M Pectic acid lyase
LEPNOIND_03619 5.6e-109 J Acetyltransferase (GNAT) domain
LEPNOIND_03620 2.9e-131 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
LEPNOIND_03621 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
LEPNOIND_03622 0.0 lplA7 G Bacterial extracellular solute-binding protein
LEPNOIND_03623 8.2e-168 lplC1 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_03624 3.1e-173 lplB P Binding-protein-dependent transport system inner membrane component
LEPNOIND_03625 2.3e-276 araC7 T helix_turn_helix, arabinose operon control protein
LEPNOIND_03626 0.0 2.7.13.3 T Histidine kinase
LEPNOIND_03627 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
LEPNOIND_03628 3.8e-205 glcP G Major Facilitator Superfamily
LEPNOIND_03629 5.2e-192 xylR3 2.7.1.2 GK ROK family
LEPNOIND_03630 1.7e-279 M1-1044 S Belongs to the UPF0061 (SELO) family
LEPNOIND_03631 7.1e-217 uxaA 4.2.1.7 G D-galactarate dehydratase / Altronate hydrolase, C terminus
LEPNOIND_03632 4.6e-48 uxaA 4.2.1.7 G SAF
LEPNOIND_03633 3.1e-168 G Tripartite ATP-independent periplasmic transporter, DctM component
LEPNOIND_03634 3.2e-20 G Tripartite ATP-independent periplasmic transporter, DctM component
LEPNOIND_03635 7.8e-91 G Tripartite ATP-independent periplasmic transporters, DctQ component
LEPNOIND_03636 2e-194 dctP G Bacterial extracellular solute-binding protein, family 7
LEPNOIND_03637 3.4e-160 K AraC-like ligand binding domain
LEPNOIND_03638 6e-168 Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LEPNOIND_03639 6.8e-138 ygaJ E Belongs to the peptidase S51 family
LEPNOIND_03640 1.1e-163 S Alpha beta hydrolase
LEPNOIND_03641 3.6e-177 yjiA S Cobalamin biosynthesis protein CobW
LEPNOIND_03642 1.1e-192 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
LEPNOIND_03643 5.6e-257 adcA P Zinc-uptake complex component A periplasmic
LEPNOIND_03644 2.1e-134 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LEPNOIND_03645 8.5e-132 adcB P ABC 3 transport family
LEPNOIND_03646 4e-265 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEPNOIND_03647 5.3e-167 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
LEPNOIND_03648 8.9e-164 MA20_14845 4.2.1.141 S Fumarylacetoacetate (FAA) hydrolase family
LEPNOIND_03649 3e-139 K helix_turn_helix isocitrate lyase regulation
LEPNOIND_03650 0.0 yjhG 4.2.1.82 EG Dehydratase family
LEPNOIND_03651 2.1e-242 yjhF EG COG2610 H gluconate symporter and related permeases
LEPNOIND_03652 5.9e-32 K MerR family transcriptional regulator
LEPNOIND_03653 7.9e-140 IQ Enoyl-(Acyl carrier protein) reductase
LEPNOIND_03654 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEPNOIND_03655 1.7e-209 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
LEPNOIND_03656 4.4e-43 ulaB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
LEPNOIND_03657 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
LEPNOIND_03658 1.5e-40
LEPNOIND_03659 3.6e-52
LEPNOIND_03660 5.2e-267 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEPNOIND_03661 3.2e-80 fld C Flavodoxin
LEPNOIND_03662 7.1e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LEPNOIND_03663 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEPNOIND_03664 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEPNOIND_03665 1.8e-44 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEPNOIND_03666 5.6e-91 yizA S DinB family
LEPNOIND_03667 9.9e-180
LEPNOIND_03669 1.4e-157 yufQ S Belongs to the binding-protein-dependent transport system permease family
LEPNOIND_03670 1.5e-189 yufP S Belongs to the binding-protein-dependent transport system permease family
LEPNOIND_03671 3.4e-283 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LEPNOIND_03672 5e-204 bmpA S ABC-type transport system, periplasmic component surface lipoprotein
LEPNOIND_03673 1.5e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
LEPNOIND_03674 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEPNOIND_03675 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LEPNOIND_03676 8.3e-131 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LEPNOIND_03677 6.7e-153 fhuC 3.6.3.34 HP ABC transporter
LEPNOIND_03678 3.8e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPNOIND_03679 5.9e-178 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEPNOIND_03681 2.3e-26 mepA V MATE efflux family protein
LEPNOIND_03682 7.6e-171 lacX G Aldose 1-epimerase
LEPNOIND_03683 0.0 acyII 3.5.1.11, 3.5.1.97 S Penicillin amidase
LEPNOIND_03684 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LEPNOIND_03685 1.2e-49 yerC S protein conserved in bacteria
LEPNOIND_03686 0.0 3.5.4.2 F adenine deaminase
LEPNOIND_03687 7.1e-200 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
LEPNOIND_03689 1.4e-159 opuAC E glycine betaine
LEPNOIND_03690 1e-148 proW P glycine betaine
LEPNOIND_03691 9.4e-220 gbuA 3.6.3.32 E glycine betaine
LEPNOIND_03692 2.2e-96 K Belongs to the GbsR family
LEPNOIND_03694 3.8e-18
LEPNOIND_03695 6.2e-21
LEPNOIND_03696 6.2e-44 M nuclease activity
LEPNOIND_03705 1.5e-07
LEPNOIND_03713 0.0 yobO M Pectate lyase superfamily protein
LEPNOIND_03715 1.1e-36 S Protein of unknown function (DUF3021)
LEPNOIND_03716 3e-48 yxcB K Transcriptional regulator C-terminal region
LEPNOIND_03717 1.1e-49 ybzH K Helix-turn-helix domain
LEPNOIND_03718 3.9e-202 ybcL EGP Major facilitator Superfamily
LEPNOIND_03719 1.1e-281 yhjG CH FAD binding domain
LEPNOIND_03720 5.2e-66 J oxidation-reduction process
LEPNOIND_03721 3.2e-83 yvmB1 K helix_turn_helix multiple antibiotic resistance protein
LEPNOIND_03722 2.7e-171 S thiolester hydrolase activity
LEPNOIND_03723 1.4e-228 eph 3.3.2.9 S Epoxide hydrolase N terminus
LEPNOIND_03724 2.6e-10 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPNOIND_03725 8.5e-251 npr 1.11.1.1 P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LEPNOIND_03726 1.6e-106 K Bacterial transcriptional repressor C-terminal
LEPNOIND_03727 4.2e-77 nsrR3 K Transcriptional regulator
LEPNOIND_03728 6.6e-257 ypfE EGP Fungal trichothecene efflux pump (TRI12)
LEPNOIND_03729 1.5e-66
LEPNOIND_03730 2.2e-93 2.7.1.48, 3.1.3.18 F uridine kinase
LEPNOIND_03731 1.7e-140 K helix_turn_helix, mercury resistance
LEPNOIND_03732 3.1e-275 pbpE V Beta-lactamase
LEPNOIND_03733 1.3e-44 ykvN K HxlR-like helix-turn-helix
LEPNOIND_03734 2.4e-32 yjcS S Antibiotic biosynthesis monooxygenase
LEPNOIND_03735 7.1e-203 S homoserine kinase type II (protein kinase fold)
LEPNOIND_03736 4.5e-108 S Domain of unknown function (DUF4297)
LEPNOIND_03738 7.3e-132 L AAA domain
LEPNOIND_03739 1e-164 K AraC-like ligand binding domain
LEPNOIND_03740 0.0 pbg 3.2.1.23 G beta-galactosidase
LEPNOIND_03741 0.0 K Mga helix-turn-helix domain
LEPNOIND_03742 2.9e-218 dho 3.5.2.3 S amidohydrolase
LEPNOIND_03743 4.9e-51 S PRD domain
LEPNOIND_03744 7.7e-61 S Glycine-rich SFCGS
LEPNOIND_03745 3.5e-58 S Domain of unknown function (DUF4312)
LEPNOIND_03746 6.2e-140 S Domain of unknown function (DUF4311)
LEPNOIND_03747 2.5e-113 S Domain of unknown function (DUF4310)
LEPNOIND_03748 7.3e-203 selA 2.9.1.1, 4.3.1.29 E L-seryl-tRNA selenium transferase
LEPNOIND_03749 7.4e-124 4.1.2.14 S KDGP aldolase
LEPNOIND_03751 4.4e-183 pld1 1.1.1.122 C Aldo/keto reductase family
LEPNOIND_03752 9.4e-71 H RibD C-terminal domain
LEPNOIND_03753 3.5e-58 S YjbR
LEPNOIND_03754 5.9e-55 S Glyoxalase-like domain
LEPNOIND_03755 1.7e-103 K helix_turn_helix, arabinose operon control protein
LEPNOIND_03756 4.9e-96 K Winged helix DNA-binding domain
LEPNOIND_03757 1.2e-151 pldB 3.1.1.5 I Alpha beta hydrolase
LEPNOIND_03758 4.3e-177 rocF 3.5.3.1, 3.5.3.11 E Arginase family
LEPNOIND_03759 3.4e-58 ydzF K HxlR-like helix-turn-helix
LEPNOIND_03760 7.5e-244 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEPNOIND_03761 1.1e-130 L DNA alkylation repair enzyme
LEPNOIND_03762 5.7e-58 S AAA domain
LEPNOIND_03763 2.2e-99 5.4.2.11 G Phosphoglycerate mutase family
LEPNOIND_03764 4.2e-198 yxjM T Signal transduction histidine kinase
LEPNOIND_03765 6.4e-111 KT LuxR family transcriptional regulator
LEPNOIND_03766 8.9e-170 V COG1131 ABC-type multidrug transport system, ATPase component
LEPNOIND_03767 5.5e-231 V ABC-2 family transporter protein
LEPNOIND_03768 1.5e-184 V ABC-2 type transporter
LEPNOIND_03769 5.6e-144 gspA M Glycosyl transferase family 8
LEPNOIND_03770 7.7e-56 yxjI S LURP-one-related
LEPNOIND_03771 1e-142 adcA P Belongs to the bacterial solute-binding protein 9 family
LEPNOIND_03772 4e-102 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEPNOIND_03774 2.9e-110 M Peptidoglycan-binding domain 1 protein
LEPNOIND_03775 6.1e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
LEPNOIND_03776 4.9e-48
LEPNOIND_03777 3.8e-105 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEPNOIND_03778 6.9e-273 MA20_17540 P secondary active sulfate transmembrane transporter activity
LEPNOIND_03779 0.0 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 F Belongs to the 5'-nucleotidase family
LEPNOIND_03780 4.2e-53 S Regulatory protein YrvL
LEPNOIND_03781 1.3e-185 yccF K SEC-C motif
LEPNOIND_03782 1.6e-258 sdcS P Sodium:sulfate symporter transmembrane region
LEPNOIND_03783 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LEPNOIND_03784 9.4e-292 cstA T Carbon starvation protein
LEPNOIND_03785 5.1e-95
LEPNOIND_03786 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEPNOIND_03787 1.7e-257 scrA5 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEPNOIND_03788 0.0 bglX 3.2.1.21 GH3 G Belongs to the glycosyl hydrolase 3 family
LEPNOIND_03789 4.5e-279 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
LEPNOIND_03790 4e-150 rhaR2 K helix_turn_helix, arabinose operon control protein
LEPNOIND_03791 8.2e-93 mepB S MepB protein
LEPNOIND_03792 2.8e-168 yhcH V ABC transporter, ATP-binding protein
LEPNOIND_03793 8.7e-131 S ABC-2 family transporter protein
LEPNOIND_03794 2.1e-61 yhcF K Transcriptional regulator
LEPNOIND_03795 8e-123 V ATPases associated with a variety of cellular activities
LEPNOIND_03796 7e-125
LEPNOIND_03797 1.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
LEPNOIND_03798 1.3e-81 dps P Belongs to the Dps family
LEPNOIND_03799 2e-100 S B3/4 domain
LEPNOIND_03800 8.6e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LEPNOIND_03801 4.8e-96 ogt 1.17.99.6, 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEPNOIND_03802 5e-81 K Acetyltransferase (GNAT) domain
LEPNOIND_03803 5.5e-169 yhbB S Putative amidase domain
LEPNOIND_03804 1.1e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEPNOIND_03805 6e-89 yufK S Family of unknown function (DUF5366)
LEPNOIND_03806 1.4e-53 hmoB 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LEPNOIND_03807 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
LEPNOIND_03808 0.0 prkA T Ser protein kinase
LEPNOIND_03809 1.4e-104 sipV 3.4.21.89 U Belongs to the peptidase S26 family
LEPNOIND_03810 3.4e-140 cysA1 S AAA domain
LEPNOIND_03811 2.7e-216 yhbH S Belongs to the UPF0229 family
LEPNOIND_03813 1e-165 K Bacterial regulatory proteins, tetR family
LEPNOIND_03814 5.1e-268 EGP Major facilitator Superfamily
LEPNOIND_03815 2.7e-177 drrA V COG1131 ABC-type multidrug transport system, ATPase component
LEPNOIND_03816 1.7e-148 drrB V Transport permease protein
LEPNOIND_03818 5.7e-88 S Protein of unknown function (DUF664)
LEPNOIND_03819 1.2e-252 3.2.1.51, 4.2.2.23 GH95,PL11 G Right handed beta helix region
LEPNOIND_03820 3.5e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_03821 2.6e-253 E Sodium:solute symporter family
LEPNOIND_03822 2.1e-126 K UTRA
LEPNOIND_03823 1.1e-275 4.3.2.1 E argininosuccinate lyase
LEPNOIND_03824 3.3e-132 yvoA K transcriptional
LEPNOIND_03825 2.2e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEPNOIND_03826 1.8e-136 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEPNOIND_03827 1e-131 frp 1.5.1.39 C Oxidoreductase
LEPNOIND_03828 2.2e-226 mtnE 2.6.1.83 E Aminotransferase
LEPNOIND_03829 2.4e-118 ycgM Q Fumarylacetoacetate (FAA) hydrolase family
LEPNOIND_03830 1.1e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEPNOIND_03831 1.4e-71
LEPNOIND_03833 5.4e-305 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LEPNOIND_03834 2.5e-124 sfsA S Sugar fermentation stimulation protein
LEPNOIND_03835 4.3e-305 glpD 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
LEPNOIND_03836 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LEPNOIND_03837 4.4e-274 ycgB S Stage V sporulation protein R
LEPNOIND_03838 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEPNOIND_03839 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEPNOIND_03840 9.6e-233 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEPNOIND_03841 9.6e-150 htpX O Peptidase family M48
LEPNOIND_03842 7.2e-95 lemA S LemA family
LEPNOIND_03843 8.5e-218 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
LEPNOIND_03844 2.8e-257 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
LEPNOIND_03845 1.9e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
LEPNOIND_03846 1.2e-135 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LEPNOIND_03847 3.6e-285 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LEPNOIND_03849 4.3e-217
LEPNOIND_03850 1.8e-78 K Sigma-70, region 4
LEPNOIND_03851 2.6e-205 msmK P Belongs to the ABC transporter superfamily
LEPNOIND_03852 1.7e-162 lrp QT PucR C-terminal helix-turn-helix domain
LEPNOIND_03853 4.1e-22
LEPNOIND_03854 4.2e-17 yheE S Family of unknown function (DUF5342)
LEPNOIND_03855 7e-209 yheB S Belongs to the UPF0754 family
LEPNOIND_03856 1.4e-54 yheA S Belongs to the UPF0342 family
LEPNOIND_03857 1.4e-158 yhaX S hydrolases of the HAD superfamily
LEPNOIND_03859 4.2e-42
LEPNOIND_03860 1.3e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEPNOIND_03861 3.3e-261 T PhoQ Sensor
LEPNOIND_03862 8e-182 yhaM L Shows a 3'-5' exoribonuclease activity
LEPNOIND_03863 6.2e-45 yhaL S Sporulation protein YhaL
LEPNOIND_03864 1.4e-160 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEPNOIND_03866 1.7e-108 S Protein conserved in bacteria
LEPNOIND_03867 1.2e-108 hpr K Negative regulator of protease production and sporulation
LEPNOIND_03868 2.4e-54 yhaH D gas vesicle protein
LEPNOIND_03869 4.6e-210 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LEPNOIND_03870 8.4e-75 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LEPNOIND_03871 7.1e-138 ecsA V transporter (ATP-binding protein)
LEPNOIND_03872 3.1e-215 ecsB U ABC transporter
LEPNOIND_03873 9.9e-129 ecsC S EcsC protein family
LEPNOIND_03874 1.1e-122 ccdA O cytochrome c biogenesis protein
LEPNOIND_03875 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEPNOIND_03876 2.1e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LEPNOIND_03877 1.3e-181 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LEPNOIND_03878 1.1e-264 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LEPNOIND_03880 1.8e-101 spo0B T Sporulation initiation phospho-transferase B, C-terminal
LEPNOIND_03881 1.1e-223 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEPNOIND_03882 1.8e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
LEPNOIND_03883 1.3e-162 pheA 4.2.1.51 E Prephenate dehydratase
LEPNOIND_03884 1.5e-90 niaR S small molecule binding protein (contains 3H domain)
LEPNOIND_03885 4.4e-208 nifS 2.8.1.7 E Cysteine desulfurase
LEPNOIND_03886 3.1e-289 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
LEPNOIND_03887 7.1e-150 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
LEPNOIND_03888 3.6e-210 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LEPNOIND_03889 1.5e-182 safA M spore coat assembly protein SafA
LEPNOIND_03890 5.6e-22 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEPNOIND_03891 2.9e-63 1.9.3.1 C cytochrome c oxidase subunit II
LEPNOIND_03892 8.4e-93 bofC S BofC C-terminal domain
LEPNOIND_03893 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEPNOIND_03894 6.8e-184 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEPNOIND_03895 6.3e-28 yrzS S Protein of unknown function (DUF2905)
LEPNOIND_03896 2e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEPNOIND_03897 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEPNOIND_03898 3.9e-38 yajC U Preprotein translocase subunit YajC
LEPNOIND_03899 1.6e-61 yrzE S Protein of unknown function (DUF3792)
LEPNOIND_03900 8e-79 ycaP S membrane
LEPNOIND_03901 4.8e-27 yodI
LEPNOIND_03902 3.3e-262 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEPNOIND_03903 5.7e-22 yrzD S Post-transcriptional regulator
LEPNOIND_03904 3e-232 secD U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LEPNOIND_03905 1.2e-145 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LEPNOIND_03906 1.8e-39 yrvD S Lipopolysaccharide assembly protein A domain
LEPNOIND_03907 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LEPNOIND_03908 4.1e-92 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEPNOIND_03909 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEPNOIND_03910 3.9e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEPNOIND_03911 1.7e-187 cytR 5.1.1.1 K LacI family transcriptional regulator
LEPNOIND_03912 1.4e-143 thuA G Trehalose utilisation
LEPNOIND_03913 2.4e-192 S Oxidoreductase family, C-terminal alpha/beta domain
LEPNOIND_03914 1.3e-220 V Belongs to the UPF0214 family
LEPNOIND_03916 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
LEPNOIND_03917 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LEPNOIND_03918 3.8e-221 1.1.1.3 E homoserine dehydrogenase
LEPNOIND_03919 4e-50
LEPNOIND_03920 3.6e-218 yxjG 2.1.1.14 E Methionine synthase
LEPNOIND_03921 6.3e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LEPNOIND_03922 1.5e-107 rsfA S Transcriptional regulator
LEPNOIND_03923 1.2e-233 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LEPNOIND_03924 1.6e-70 cymR K Transcriptional regulator
LEPNOIND_03925 1.7e-215 iscS 2.8.1.7 E Cysteine desulfurase
LEPNOIND_03926 3.9e-217 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEPNOIND_03927 2.3e-39 S COG0457 FOG TPR repeat
LEPNOIND_03928 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEPNOIND_03929 9.3e-83 yrrD S protein conserved in bacteria
LEPNOIND_03930 2.1e-30 yrzR
LEPNOIND_03931 2.2e-188 yrrI S AI-2E family transporter
LEPNOIND_03932 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEPNOIND_03933 1.9e-43 yrzL S Belongs to the UPF0297 family
LEPNOIND_03934 6.1e-73 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEPNOIND_03935 4.1e-25 yrzB S Belongs to the UPF0473 family
LEPNOIND_03936 2.6e-211 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEPNOIND_03937 3.6e-117 yrrM 2.1.1.104 S O-methyltransferase
LEPNOIND_03938 1.4e-113 udk 2.7.1.48 F Cytidine monophosphokinase
LEPNOIND_03939 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEPNOIND_03940 8.7e-12 S Protein of unknown function (DUF1510)
LEPNOIND_03941 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
LEPNOIND_03942 1.6e-149 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LEPNOIND_03943 7.3e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEPNOIND_03944 1.4e-10 S YrhC-like protein
LEPNOIND_03945 1.3e-78 M1-460
LEPNOIND_03946 1.8e-292 E Bacterial extracellular solute-binding proteins, family 5 Middle
LEPNOIND_03947 5.9e-149 appF P ATPases associated with a variety of cellular activities
LEPNOIND_03948 2.7e-143 oppD P Oligopeptide/dipeptide transporter, C-terminal region
LEPNOIND_03949 1.1e-156 EP N-terminal TM domain of oligopeptide transport permease C
LEPNOIND_03950 4.4e-153 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_03951 2.6e-109 arpR K Bacterial regulatory proteins, tetR family
LEPNOIND_03952 0.0 malS 3.2.1.1 GH13 G Carbohydrate binding domain
LEPNOIND_03953 3.9e-113 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LEPNOIND_03954 1.2e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
LEPNOIND_03955 2.8e-252 S Membrane
LEPNOIND_03956 4.6e-224 hipO3 3.5.1.47 S amidohydrolase
LEPNOIND_03957 4.6e-169 ybaS 1.1.1.58 S Na -dependent transporter
LEPNOIND_03958 2.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEPNOIND_03959 5.5e-25
LEPNOIND_03961 5.2e-54
LEPNOIND_03963 1.1e-187 V COG0842 ABC-type multidrug transport system, permease component
LEPNOIND_03964 5.5e-220 V COG0842 ABC-type multidrug transport system, permease component
LEPNOIND_03965 8e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
LEPNOIND_03966 1.1e-107 KT LuxR family transcriptional regulator
LEPNOIND_03967 6.8e-201 yxjM T Signal transduction histidine kinase
LEPNOIND_03968 1.2e-91 ttr K GCN5 family acetyltransferase
LEPNOIND_03969 1.2e-153 fhuD P Periplasmic binding protein
LEPNOIND_03970 1.6e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_03971 6.3e-233 gntT EG COG2610 H gluconate symporter and related permeases
LEPNOIND_03972 9.2e-200 gutB 1.1.1.14 E Dehydrogenase
LEPNOIND_03973 1.6e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_03974 2.7e-188 K helix_turn _helix lactose operon repressor
LEPNOIND_03975 3.3e-203 cpg2 3.4.17.11 E Peptidase dimerisation domain
LEPNOIND_03976 1.6e-238 purD 6.3.4.13 F Belongs to the GARS family
LEPNOIND_03977 1.1e-284 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LEPNOIND_03978 8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEPNOIND_03979 1.9e-192 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LEPNOIND_03980 5.5e-272 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEPNOIND_03981 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEPNOIND_03982 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEPNOIND_03983 1.4e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEPNOIND_03984 6.5e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LEPNOIND_03985 9.3e-250 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEPNOIND_03986 6.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEPNOIND_03987 3.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEPNOIND_03988 1.8e-128 S CAAX protease self-immunity
LEPNOIND_03989 5.6e-103 rimL 1.1.1.25 J Acetyltransferase (GNAT) domain
LEPNOIND_03990 1.6e-122 S PFAM AIG2 family protein
LEPNOIND_03991 3.1e-110
LEPNOIND_03992 8.6e-68 S Calcium/calmodulin dependent protein kinase II association domain
LEPNOIND_03993 1.1e-30 yebG S NETI protein
LEPNOIND_03994 2.2e-20 repB L Initiator Replication protein
LEPNOIND_03995 2.7e-261 tctA S Tripartite tricarboxylate transporter TctA family
LEPNOIND_03996 9.1e-75 S Tripartite tricarboxylate transporter TctB family
LEPNOIND_03997 7.6e-191 S Tripartite tricarboxylate transporter family receptor
LEPNOIND_03998 3.6e-120 citT T response regulator
LEPNOIND_03999 8.3e-293 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LEPNOIND_04000 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
LEPNOIND_04001 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEPNOIND_04002 4.9e-310 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEPNOIND_04004 3.8e-235 G Major facilitator Superfamily
LEPNOIND_04005 1.2e-21
LEPNOIND_04007 2e-97 ypbQ S protein conserved in bacteria
LEPNOIND_04008 9.4e-211 bcsA Q Naringenin-chalcone synthase
LEPNOIND_04009 8.1e-129 mta K transcriptional
LEPNOIND_04010 2.5e-115 rimJ2 J Acetyltransferase (GNAT) domain
LEPNOIND_04011 5.5e-280 uxaC 5.3.1.12 G glucuronate isomerase
LEPNOIND_04012 1.5e-160 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LEPNOIND_04013 2e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_04014 1.7e-134 xytR K DeoR C terminal sensor domain
LEPNOIND_04015 4.5e-89 ywrA P COG2059 Chromate transport protein ChrA
LEPNOIND_04016 5.2e-107 ywrB P COG2059 Chromate transport protein ChrA
LEPNOIND_04017 4.4e-160 mqnD S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LEPNOIND_04018 6.6e-114 mqnB 2.4.2.1, 3.2.2.26, 3.2.2.9 F Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LEPNOIND_04019 8.7e-281 lipA1 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LEPNOIND_04020 1e-284 K transcriptional antiterminator
LEPNOIND_04021 1.2e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LEPNOIND_04022 0.0 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LEPNOIND_04023 1.8e-166 Q calcium- and calmodulin-responsive adenylate cyclase activity
LEPNOIND_04024 3.2e-158 proX E Substrate binding domain of ABC-type glycine betaine transport system
LEPNOIND_04025 2e-100 K Belongs to the GbsR family
LEPNOIND_04026 5.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
LEPNOIND_04027 3.8e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
LEPNOIND_04028 1.2e-138 yvfI K COG2186 Transcriptional regulators
LEPNOIND_04029 2.6e-126 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LEPNOIND_04030 9.2e-275 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LEPNOIND_04031 5.9e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LEPNOIND_04032 0.0 lldP C L-lactate permease
LEPNOIND_04033 4.8e-15
LEPNOIND_04034 5.8e-230 cypA C Cytochrome P450
LEPNOIND_04035 3.4e-275 ydaH H AbgT putative transporter family
LEPNOIND_04036 0.0 htpG O Molecular chaperone. Has ATPase activity
LEPNOIND_04037 2.1e-102 yaaI Q Isochorismatase family
LEPNOIND_04038 7e-75 ygaO
LEPNOIND_04039 5.4e-27 K Transcriptional regulator
LEPNOIND_04040 0.0 sasH 3.1.3.5, 3.6.1.45 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
LEPNOIND_04042 8.1e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LEPNOIND_04043 5.4e-289 prdR KT Transcriptional regulator
LEPNOIND_04044 1.2e-171 putA E Proline dehydrogenase
LEPNOIND_04045 1.1e-150 ykoQ S Calcineurin-like phosphoesterase superfamily domain
LEPNOIND_04046 2.2e-74 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEPNOIND_04047 7.7e-307 S proteins of the AP superfamily
LEPNOIND_04049 2.2e-211 pbuG S permease
LEPNOIND_04050 3.3e-70
LEPNOIND_04051 2.9e-181 aph 2.7.11.1 S Phosphotransferase enzyme family
LEPNOIND_04052 4.8e-219 G Transmembrane secretion effector
LEPNOIND_04053 1.8e-24 S YfhD-like protein
LEPNOIND_04054 1.1e-65 dhaM 2.7.1.121 S PTS system fructose IIA component
LEPNOIND_04055 5.8e-109 dhaL 2.7.1.121 S Dak2
LEPNOIND_04056 5.1e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
LEPNOIND_04057 2.5e-85 M1-431 S Protein of unknown function (DUF1706)
LEPNOIND_04058 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEPNOIND_04059 5e-232 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
LEPNOIND_04060 1.6e-42 ulaB_1 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
LEPNOIND_04061 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
LEPNOIND_04062 5.2e-55 2.7.1.48, 3.1.3.18 F uridine kinase
LEPNOIND_04063 6.4e-58 K MerR, DNA binding
LEPNOIND_04064 2.2e-123 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LEPNOIND_04065 0.0 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
LEPNOIND_04066 1.5e-71 3.1.21.3 L Type I restriction modification DNA specificity domain
LEPNOIND_04067 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
LEPNOIND_04068 6.6e-185 yxeA V FtsX-like permease family
LEPNOIND_04069 6.9e-116 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
LEPNOIND_04070 1.1e-84 K Bacterial regulatory proteins, tetR family
LEPNOIND_04071 2.1e-210 S Erythromycin esterase
LEPNOIND_04072 1.2e-169 K LysR substrate binding domain
LEPNOIND_04073 2.3e-187 ord 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
LEPNOIND_04074 5.5e-240 C Na+/H+ antiporter family
LEPNOIND_04075 4.1e-77 S glyoxalase bleomycin resistance protein dioxygenase
LEPNOIND_04076 2.9e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LEPNOIND_04077 0.0 yebA E COG1305 Transglutaminase-like enzymes
LEPNOIND_04078 5.9e-219 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LEPNOIND_04079 2e-172 yeaC S COG0714 MoxR-like ATPases
LEPNOIND_04080 5.3e-101 CO Thioredoxin
LEPNOIND_04081 2.6e-185 3.1.4.53 Q Calcineurin-like phosphoesterase
LEPNOIND_04084 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
LEPNOIND_04085 6e-108 C nitroreductase
LEPNOIND_04086 1.9e-117 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEPNOIND_04087 2.9e-76 S Bacteriophage holin family
LEPNOIND_04089 0.0 L Phage minor structural protein
LEPNOIND_04090 9.1e-138 S Phage tail protein
LEPNOIND_04091 8.5e-161 D Phage tail tape measure protein, TP901 family
LEPNOIND_04092 1.5e-77
LEPNOIND_04093 3.3e-71
LEPNOIND_04094 1.4e-150 S Short C-terminal domain
LEPNOIND_04095 1.4e-212 mez_1 1.1.1.38 C Malate dehydrogenase
LEPNOIND_04096 6.1e-244 maeN C COG3493 Na citrate symporter
LEPNOIND_04097 8.4e-112 dcuR T COG4565 Response regulator of citrate malate metabolism
LEPNOIND_04098 2.2e-261 malK 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LEPNOIND_04099 4.6e-73 wecC 1.1.1.336 M ArpU family transcriptional regulator
LEPNOIND_04100 1.3e-148 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEPNOIND_04101 4e-119 ehuD E Binding-protein-dependent transport system inner membrane component
LEPNOIND_04102 5.5e-113 ehuC E Binding-protein-dependent transport system inner membrane component
LEPNOIND_04103 5.9e-149 ehuB ET Bacterial periplasmic substrate-binding proteins
LEPNOIND_04104 5.2e-145
LEPNOIND_04105 1.6e-154 S Haloacid dehalogenase-like hydrolase
LEPNOIND_04106 3.6e-182 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEPNOIND_04107 6.2e-70 wxcN GT2 S GtrA-like protein
LEPNOIND_04108 0.0 yfhO S Bacterial membrane protein YfhO
LEPNOIND_04111 1.1e-86 MA20_19235 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LEPNOIND_04112 1.2e-137 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LEPNOIND_04113 1.2e-109 yjgD S Protein of unknown function (DUF1641)
LEPNOIND_04114 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
LEPNOIND_04115 9.9e-141 focA P Formate/nitrite transporter
LEPNOIND_04116 5.7e-36 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LEPNOIND_04117 1.1e-74 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
LEPNOIND_04118 1.7e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
LEPNOIND_04119 1.2e-241 moeA 2.10.1.1 H molybdopterin
LEPNOIND_04120 6.7e-187 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LEPNOIND_04121 6.7e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
LEPNOIND_04122 1.4e-104 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LEPNOIND_04123 9.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LEPNOIND_04124 6.6e-273 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
LEPNOIND_04125 3.2e-152 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEPNOIND_04126 3.9e-122 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LEPNOIND_04127 1.9e-130 S carbohydrate derivative metabolic process
LEPNOIND_04128 5e-224 ulaA S PTS system ascorbate-specific transporter subunit IIC
LEPNOIND_04129 1.4e-41 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
LEPNOIND_04130 4.8e-73 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEPNOIND_04131 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
LEPNOIND_04132 2.6e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEPNOIND_04133 5.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEPNOIND_04134 9.5e-119 ydiL S CAAX protease self-immunity
LEPNOIND_04136 9.7e-208 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
LEPNOIND_04137 3.3e-152 P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
LEPNOIND_04138 1.6e-112 metI P COG2011 ABC-type metal ion transport system, permease component
LEPNOIND_04139 1.7e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEPNOIND_04140 3.6e-130 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEPNOIND_04141 1.4e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LEPNOIND_04142 2.3e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEPNOIND_04143 2.7e-311 ydiF S ABC transporter
LEPNOIND_04144 3.2e-181 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEPNOIND_04145 4.9e-87 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LEPNOIND_04146 1.1e-130 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
LEPNOIND_04147 4.9e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
LEPNOIND_04148 2.9e-187 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LEPNOIND_04151 1.2e-213 megL 2.5.1.48, 2.5.1.49, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
LEPNOIND_04152 6.9e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEPNOIND_04153 6e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEPNOIND_04154 1.3e-120 sapB S MgtC SapB transporter
LEPNOIND_04156 2.2e-56 S LXG domain of WXG superfamily
LEPNOIND_04157 1.1e-59
LEPNOIND_04158 1.6e-78 S LXG domain of WXG superfamily
LEPNOIND_04159 1e-59
LEPNOIND_04160 2.1e-22
LEPNOIND_04162 3.6e-57
LEPNOIND_04163 9.6e-80 S SMI1-KNR4 cell-wall
LEPNOIND_04164 6.9e-49
LEPNOIND_04165 2.6e-64
LEPNOIND_04166 1.2e-55
LEPNOIND_04168 2.2e-78
LEPNOIND_04169 4.9e-37 S DNA/RNA non-specific endonuclease
LEPNOIND_04170 8.3e-26 S DNA/RNA non-specific endonuclease
LEPNOIND_04171 1.9e-67 S Protein of unknown function, DUF600
LEPNOIND_04172 2.8e-79
LEPNOIND_04173 2.8e-84 S Protein of unknown function (DUF1569)
LEPNOIND_04174 1.5e-76 yuxK S protein conserved in bacteria
LEPNOIND_04175 8.9e-95 ykkA S Protein of unknown function (DUF664)
LEPNOIND_04176 5.5e-272 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEPNOIND_04177 3e-105 argO S Lysine exporter protein LysE YggA
LEPNOIND_04178 7.2e-74 lrpC K helix_turn_helix ASNC type
LEPNOIND_04179 7.1e-74 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEPNOIND_04180 3.8e-257 T His Kinase A (phosphoacceptor) domain
LEPNOIND_04181 3.1e-124 K Transcriptional regulatory protein, C terminal
LEPNOIND_04182 1.2e-135 mutG S ABC-2 family transporter protein
LEPNOIND_04183 2.4e-125 spaE S ABC-2 family transporter protein
LEPNOIND_04184 3.9e-125 mutF V ABC transporter, ATP-binding protein
LEPNOIND_04185 1.1e-172 yisR1 K AraC-like ligand binding domain
LEPNOIND_04186 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
LEPNOIND_04187 1.8e-272 G Bacterial extracellular solute-binding protein
LEPNOIND_04188 1.5e-172 P Binding-protein-dependent transport system inner membrane component
LEPNOIND_04189 5.1e-153 G Binding-protein-dependent transport system inner membrane component
LEPNOIND_04190 2.2e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
LEPNOIND_04191 4.3e-68 K Helix-turn-helix XRE-family like proteins
LEPNOIND_04192 5.5e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
LEPNOIND_04193 2.1e-299 E COG0747 ABC-type dipeptide transport system, periplasmic component
LEPNOIND_04194 2.5e-161 nhaR K LysR substrate binding domain
LEPNOIND_04195 8.9e-256 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LEPNOIND_04196 3.2e-162 yocS S -transporter
LEPNOIND_04197 4.6e-263 dld 1.1.1.303, 1.1.1.4, 1.1.2.4, 1.1.3.15 C Glycolate oxidase subunit
LEPNOIND_04198 7.9e-307 T COG0642 Signal transduction histidine kinase
LEPNOIND_04199 2.7e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LEPNOIND_04200 1.8e-195 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
LEPNOIND_04201 1.2e-133 cysT O COG0555 ABC-type sulfate transport system, permease component
LEPNOIND_04202 2.9e-134 cysW P COG4208 ABC-type sulfate transport system, permease component
LEPNOIND_04203 6.6e-201 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LEPNOIND_04204 4.6e-196
LEPNOIND_04205 7.4e-141 S transport system, ATPase component
LEPNOIND_04206 2.7e-172 S Belongs to the binding-protein-dependent transport system permease family
LEPNOIND_04207 2.1e-177 S transport system, periplasmic component
LEPNOIND_04208 1.8e-229 S Sulphur transport
LEPNOIND_04209 1.8e-103 ynaD J Acetyltransferase (GNAT) domain
LEPNOIND_04210 4.1e-65 XK27_04860 S Domain of unknown function (DUF4440)
LEPNOIND_04211 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
LEPNOIND_04212 1.2e-183 dppD P Belongs to the ABC transporter superfamily
LEPNOIND_04213 4.9e-190 appF E Belongs to the ABC transporter superfamily
LEPNOIND_04214 3.2e-303 E COG0747 ABC-type dipeptide transport system, periplasmic component
LEPNOIND_04215 2.6e-183 dppB EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_04216 2.2e-160 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEPNOIND_04217 2.7e-165 3.4.11.5 I Alpha/beta hydrolase family
LEPNOIND_04218 1.8e-65 gpm5 3.1.3.3, 5.4.2.11 G alpha-ribazole phosphatase activity
LEPNOIND_04219 1.2e-106 tetR K Bacterial regulatory proteins, tetR family
LEPNOIND_04220 1.3e-246 matE V MatE
LEPNOIND_04221 3.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEPNOIND_04222 2.3e-142 phnE 3.6.1.63 P ABC transporter
LEPNOIND_04223 2.9e-137 phnE 3.6.1.63 P ABC transporter
LEPNOIND_04224 7.5e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LEPNOIND_04225 1.6e-171 phnD P Phosphonate ABC transporter
LEPNOIND_04226 0.0 uvrD 3.6.4.12 L DNA helicase
LEPNOIND_04227 2e-308 yfiB3 V ABC transporter
LEPNOIND_04228 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEPNOIND_04229 2e-233 pilS 2.7.13.3 T Histidine kinase
LEPNOIND_04230 6.4e-295 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEPNOIND_04231 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LEPNOIND_04232 1.6e-94 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LEPNOIND_04233 1.9e-245 agcS E Sodium alanine symporter
LEPNOIND_04234 4.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEPNOIND_04235 4.2e-310 yngK T Glycosyl hydrolase-like 10
LEPNOIND_04236 0.0 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LEPNOIND_04237 1.1e-267 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEPNOIND_04238 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LEPNOIND_04239 1e-125 treR K transcriptional
LEPNOIND_04240 1.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LEPNOIND_04241 1.9e-211 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LEPNOIND_04242 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEPNOIND_04243 4.5e-135 fruR K Transcriptional regulator
LEPNOIND_04244 1.1e-164 fruB 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
LEPNOIND_04245 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LEPNOIND_04246 2.2e-182 mreB D Rod-share determining protein MreBH
LEPNOIND_04247 2.9e-238 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LEPNOIND_04248 1e-56
LEPNOIND_04249 2e-46 abrB K SpoVT / AbrB like domain
LEPNOIND_04250 1.4e-40
LEPNOIND_04251 3.2e-112 rnhA 3.1.26.4 L Caulimovirus viroplasmin
LEPNOIND_04252 1.5e-258 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LEPNOIND_04253 3.8e-251 iucD_1 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
LEPNOIND_04254 4.3e-296 katB 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LEPNOIND_04255 0.0 pepF2 E COG1164 Oligoendopeptidase F
LEPNOIND_04256 5.9e-146
LEPNOIND_04257 2.5e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LEPNOIND_04258 5.8e-247 cydA 1.10.3.14 C oxidase, subunit
LEPNOIND_04259 2.2e-21 S Fur-regulated basic protein B
LEPNOIND_04262 1.8e-147 yfkD S YfkD-like protein
LEPNOIND_04263 3.8e-220 yfkA S YfkB-like domain
LEPNOIND_04264 3.8e-119 gpmB 5.4.2.11 G Belongs to the phosphoglycerate mutase family
LEPNOIND_04265 2.5e-245 yhdP S COG1253 Hemolysins and related proteins containing CBS domains
LEPNOIND_04266 1.9e-144 S Domain of unknown function (DUF368)
LEPNOIND_04267 2.9e-150 pdaA G deacetylase
LEPNOIND_04268 1.1e-172 ahpF 1.8.1.9 O Pyridine nucleotide-disulphide oxidoreductase
LEPNOIND_04269 1.5e-71 ywgB K Transcriptional regulator
LEPNOIND_04271 1.6e-61
LEPNOIND_04272 7.2e-272 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEPNOIND_04273 1.3e-206 mccF 3.4.17.13 V LD-carboxypeptidase
LEPNOIND_04274 5.5e-49
LEPNOIND_04275 2.5e-169 yfhF S nucleoside-diphosphate sugar epimerase
LEPNOIND_04276 3.9e-145 recX 2.4.1.337 GT4 S Modulates RecA activity
LEPNOIND_04277 1.4e-53 yfhH S Protein of unknown function (DUF1811)
LEPNOIND_04278 1.2e-21 S YpzG-like protein
LEPNOIND_04280 2.8e-190 yfhP S membrane-bound metal-dependent
LEPNOIND_04281 3e-209 mutY L A G-specific
LEPNOIND_04282 1.2e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_04283 4.1e-59
LEPNOIND_04284 6.9e-19 yfhS
LEPNOIND_04285 1.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEPNOIND_04286 5.4e-16 S Small, acid-soluble spore protein, gamma-type
LEPNOIND_04287 1.5e-102 ygaC J Belongs to the UPF0374 family
LEPNOIND_04288 0.0 ygaD V ABC transporter
LEPNOIND_04289 7.5e-189 ygaE S Membrane
LEPNOIND_04290 1.9e-247 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LEPNOIND_04291 1.6e-87 bcp 1.11.1.15 O Peroxiredoxin
LEPNOIND_04292 3.4e-180 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEPNOIND_04293 2.7e-48 S Cyclic-di-AMP receptor
LEPNOIND_04294 1.5e-79 perR P Belongs to the Fur family
LEPNOIND_04295 3.6e-58 ygzB S UPF0295 protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)