ORF_ID e_value Gene_name EC_number CAZy COGs Description
MIIMCIKM_00001 1.9e-71 S NMT1-like family
MIIMCIKM_00002 0.0 S Tripartite ATP-independent periplasmic transporter, DctM component
MIIMCIKM_00003 7.6e-121 K FCD
MIIMCIKM_00004 1.1e-122 K COG2186 Transcriptional regulators
MIIMCIKM_00005 2.6e-266 glcD 1.1.3.15 C Glycolate oxidase subunit
MIIMCIKM_00006 3.3e-222 glcF C Glycolate oxidase
MIIMCIKM_00007 2e-227 lhgO 1.1.99.2 S FAD dependent oxidoreductase
MIIMCIKM_00008 8.4e-301 QT COG2508 Regulator of polyketide synthase expression
MIIMCIKM_00010 1.1e-223 codB F cytosine purines uracil thiamine allantoin
MIIMCIKM_00011 2.3e-245 codA 3.5.4.1 F Amidohydrolase family
MIIMCIKM_00013 1.2e-246 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MIIMCIKM_00014 9.2e-118 idi I COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MIIMCIKM_00015 1.7e-176 rihB 3.2.2.1 F nucleoside hydrolase
MIIMCIKM_00016 2e-61 S CHY zinc finger
MIIMCIKM_00017 2e-236 braB E Component of the transport system for branched-chain amino acids
MIIMCIKM_00018 4.7e-88 sdpI S integral membrane protein
MIIMCIKM_00019 4.5e-225 EGP Major facilitator Superfamily
MIIMCIKM_00020 3.2e-106 GBS0088 S protein conserved in bacteria
MIIMCIKM_00021 5.2e-147 ubiE Q Methyltransferase type 11
MIIMCIKM_00022 3.4e-239 S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MIIMCIKM_00023 3.1e-46 phhB 3.5.4.33, 4.2.1.96 H pterin-4-alpha-carbinolamine dehydratase
MIIMCIKM_00024 2.3e-66 eaeH M LysM domain
MIIMCIKM_00025 4.4e-71 S YtkA-like
MIIMCIKM_00026 2.4e-259 T Histidine kinase
MIIMCIKM_00027 2.3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_00028 2.1e-177 S amine dehydrogenase activity
MIIMCIKM_00029 5.2e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIIMCIKM_00030 8.1e-73 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIIMCIKM_00031 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MIIMCIKM_00033 6.2e-96 yqeG S hydrolase of the HAD superfamily
MIIMCIKM_00034 1.8e-217 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MIIMCIKM_00035 3.6e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MIIMCIKM_00036 3e-47 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MIIMCIKM_00037 2.3e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MIIMCIKM_00038 3.6e-108 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MIIMCIKM_00039 9.8e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MIIMCIKM_00040 6.7e-164 cvfB S protein conserved in bacteria
MIIMCIKM_00041 5.3e-141 cmoA S Methyltransferase domain
MIIMCIKM_00042 7.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIIMCIKM_00043 1.9e-107 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MIIMCIKM_00044 2.5e-109 comEB 3.5.4.12 F ComE operon protein 2
MIIMCIKM_00045 2.3e-187 G Bacterial extracellular solute-binding protein, family 7
MIIMCIKM_00046 2.2e-82 G Tripartite ATP-independent periplasmic transporters, DctQ component
MIIMCIKM_00047 7.5e-207 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MIIMCIKM_00048 2.9e-130 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MIIMCIKM_00049 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MIIMCIKM_00051 1.4e-91 S Peptidase propeptide and YPEB domain
MIIMCIKM_00052 4.3e-286 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MIIMCIKM_00053 5.6e-163 yueF S transporter activity
MIIMCIKM_00054 9.4e-86 ftnA 1.16.3.2 P Iron-storage protein
MIIMCIKM_00056 1.5e-97 adk 2.7.4.3 F topology modulation protein
MIIMCIKM_00057 1.9e-212 F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MIIMCIKM_00058 3.8e-56 I alpha/beta hydrolase fold
MIIMCIKM_00059 4.4e-183 pld1 1.1.1.122 C Aldo/keto reductase family
MIIMCIKM_00060 9.4e-71 H RibD C-terminal domain
MIIMCIKM_00061 3.5e-58 S YjbR
MIIMCIKM_00062 5.9e-55 S Glyoxalase-like domain
MIIMCIKM_00063 2.4e-108 K helix_turn_helix, arabinose operon control protein
MIIMCIKM_00064 4.9e-96 K Winged helix DNA-binding domain
MIIMCIKM_00065 1.2e-151 pldB 3.1.1.5 I Alpha beta hydrolase
MIIMCIKM_00066 4.3e-177 rocF 3.5.3.1, 3.5.3.11 E Arginase family
MIIMCIKM_00067 3.4e-58 ydzF K HxlR-like helix-turn-helix
MIIMCIKM_00068 7.5e-244 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MIIMCIKM_00069 1.1e-130 L DNA alkylation repair enzyme
MIIMCIKM_00070 5.7e-58 S AAA domain
MIIMCIKM_00071 2.2e-99 5.4.2.11 G Phosphoglycerate mutase family
MIIMCIKM_00072 4.2e-198 yxjM T Signal transduction histidine kinase
MIIMCIKM_00073 6.4e-111 KT LuxR family transcriptional regulator
MIIMCIKM_00074 3.9e-190 ypbB 5.1.3.1 S protein conserved in bacteria
MIIMCIKM_00075 5.9e-44 fer C Ferredoxin
MIIMCIKM_00076 8.4e-301 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIIMCIKM_00077 1.1e-261 nox 1.6.3.4 P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MIIMCIKM_00078 2.6e-135 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MIIMCIKM_00080 1.4e-98 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
MIIMCIKM_00081 1.1e-141 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MIIMCIKM_00082 1.4e-190 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIIMCIKM_00084 0.0 resE 2.7.13.3 T Histidine kinase
MIIMCIKM_00085 9e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_00086 2e-222 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MIIMCIKM_00087 1.1e-275 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MIIMCIKM_00089 1.1e-187 V COG0842 ABC-type multidrug transport system, permease component
MIIMCIKM_00090 5.5e-220 V COG0842 ABC-type multidrug transport system, permease component
MIIMCIKM_00091 8e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
MIIMCIKM_00092 1.1e-107 KT LuxR family transcriptional regulator
MIIMCIKM_00093 6.8e-201 yxjM T Signal transduction histidine kinase
MIIMCIKM_00094 1.2e-91 ttr K GCN5 family acetyltransferase
MIIMCIKM_00095 1.2e-153 fhuD P Periplasmic binding protein
MIIMCIKM_00096 1.6e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_00097 6.3e-233 gntT EG COG2610 H gluconate symporter and related permeases
MIIMCIKM_00098 9.2e-200 gutB 1.1.1.14 E Dehydrogenase
MIIMCIKM_00099 1.6e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_00100 2.7e-188 K helix_turn _helix lactose operon repressor
MIIMCIKM_00101 3.3e-203 cpg2 3.4.17.11 E Peptidase dimerisation domain
MIIMCIKM_00102 6.7e-173 E Proline dehydrogenase
MIIMCIKM_00104 8.6e-256 2.7.1.163 S Aminoglycoside phosphotransferase
MIIMCIKM_00105 3.6e-73 K SpoVT / AbrB like domain
MIIMCIKM_00106 4.3e-222 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MIIMCIKM_00107 1.3e-142 V ABC transporter, ATP-binding protein
MIIMCIKM_00108 0.0 V FtsX-like permease family
MIIMCIKM_00109 1.7e-122 T Transcriptional regulatory protein, C terminal
MIIMCIKM_00110 3.4e-194 T Histidine kinase-like ATPases
MIIMCIKM_00111 4.8e-114 K Bacterial regulatory proteins, tetR family
MIIMCIKM_00112 1.2e-228 mefE EGP Transmembrane secretion effector
MIIMCIKM_00117 1.2e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MIIMCIKM_00118 2.9e-48 comGC U Required for transformation and DNA binding
MIIMCIKM_00119 1.5e-74 mshD NU general secretion pathway protein
MIIMCIKM_00121 1.4e-80
MIIMCIKM_00124 2e-36 yqgY S Protein of unknown function (DUF2626)
MIIMCIKM_00125 3e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MIIMCIKM_00126 6.6e-08 S Protein of unknown function (DUF2759)
MIIMCIKM_00127 3.8e-153 yqhG S Bacterial protein YqhG of unknown function
MIIMCIKM_00128 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MIIMCIKM_00129 4.1e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MIIMCIKM_00130 2.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIIMCIKM_00131 6.3e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIIMCIKM_00132 3.9e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MIIMCIKM_00133 9.5e-155 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MIIMCIKM_00134 1.8e-173 ftsK D Belongs to the FtsK SpoIIIE SftA family
MIIMCIKM_00135 4.5e-129 ymfC K Transcriptional regulator
MIIMCIKM_00136 3.6e-238 ymfF S Peptidase M16
MIIMCIKM_00137 9.2e-250 ymfH S zinc protease
MIIMCIKM_00138 8.7e-125 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_00139 5.1e-40 ymfJ S Protein of unknown function (DUF3243)
MIIMCIKM_00140 4.6e-140 ymfK S Protein of unknown function (DUF3388)
MIIMCIKM_00141 2.1e-128 ymfM S protein conserved in bacteria
MIIMCIKM_00142 8.7e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIIMCIKM_00143 5.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
MIIMCIKM_00144 1e-290 deaD 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MIIMCIKM_00145 2.3e-190 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MIIMCIKM_00146 1.6e-188 L Calcineurin-like phosphoesterase superfamily domain
MIIMCIKM_00147 1.1e-47
MIIMCIKM_00148 2.9e-111 S Integral membrane protein
MIIMCIKM_00149 2.2e-218 S Winged helix DNA-binding domain
MIIMCIKM_00150 6.9e-141 G Xylose isomerase-like TIM barrel
MIIMCIKM_00151 8.3e-193 S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_00152 3.5e-193 G Xylose isomerase
MIIMCIKM_00153 1.1e-161 S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
MIIMCIKM_00154 5.4e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MIIMCIKM_00155 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIIMCIKM_00156 1.7e-85 mrpE P Na+/H+ ion antiporter subunit
MIIMCIKM_00157 7.6e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIIMCIKM_00158 4.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIIMCIKM_00159 9.3e-66 mnhB2 P antiporter activity
MIIMCIKM_00160 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MIIMCIKM_00161 1.7e-130 T PhoQ Sensor
MIIMCIKM_00162 7.1e-112 S Nitroreductase family
MIIMCIKM_00163 3.1e-59 hxlR K transcriptional
MIIMCIKM_00164 1.9e-186 ykfD E Belongs to the ABC transporter superfamily
MIIMCIKM_00165 1.5e-174 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MIIMCIKM_00166 6.8e-178 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MIIMCIKM_00167 0.0 dppE E ABC transporter substrate-binding protein
MIIMCIKM_00168 1.8e-184 dppD P Belongs to the ABC transporter superfamily
MIIMCIKM_00169 3.3e-172 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_00170 9.4e-164 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_00171 1.8e-150 dppA E D-aminopeptidase
MIIMCIKM_00172 5.7e-236 2.7.13.3 T Histidine kinase-like ATPases
MIIMCIKM_00173 3.3e-158 ycbB1 T YcbB domain
MIIMCIKM_00174 1.5e-107 glnP P ABC transporter
MIIMCIKM_00175 7.1e-110 gluC P ABC transporter
MIIMCIKM_00176 1e-148 glnH ET Belongs to the bacterial solute-binding protein 3 family
MIIMCIKM_00177 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIIMCIKM_00178 8.1e-160 rarD S -transporter
MIIMCIKM_00179 4.5e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
MIIMCIKM_00180 9e-201 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MIIMCIKM_00181 1.8e-234 QT Transcriptional regulator
MIIMCIKM_00182 2.5e-163 sseA 2.8.1.1, 2.8.1.2 P sulfurtransferase
MIIMCIKM_00183 1.2e-250 yeeF E Amino acid permease
MIIMCIKM_00184 1.4e-112 cwlK M Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin
MIIMCIKM_00185 1.1e-231 K Helix-turn-helix XRE-family like proteins
MIIMCIKM_00186 7e-201 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MIIMCIKM_00188 1.6e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIIMCIKM_00189 1.1e-172 yfhM S Alpha beta hydrolase
MIIMCIKM_00190 7.5e-141 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MIIMCIKM_00191 7.4e-178 S Phosphotransferase system, EIIC
MIIMCIKM_00192 6.3e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MIIMCIKM_00193 1.6e-94 tag 3.2.2.20 L Methyladenine glycosylase
MIIMCIKM_00194 2.8e-128
MIIMCIKM_00195 6e-95 3.4.21.89 U Signal peptidase
MIIMCIKM_00196 0.0 vpr O Belongs to the peptidase S8 family
MIIMCIKM_00197 6.4e-156 hisJ3 3.1.3.15 E PHP domain
MIIMCIKM_00198 1e-187 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MIIMCIKM_00199 1.8e-113 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIIMCIKM_00200 3.2e-120
MIIMCIKM_00201 1.7e-196 yetN S Protein of unknown function (DUF3900)
MIIMCIKM_00202 5.7e-200 cdaR KT Sugar diacid utilization regulator
MIIMCIKM_00203 9.2e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MIIMCIKM_00204 4.2e-80 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIIMCIKM_00205 2.8e-145 map 3.4.11.18 E Methionine aminopeptidase
MIIMCIKM_00206 4.9e-72 yvbK 3.1.3.25 K acetyltransferase
MIIMCIKM_00207 4.1e-92 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIIMCIKM_00208 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MIIMCIKM_00209 1.8e-39 yrvD S Lipopolysaccharide assembly protein A domain
MIIMCIKM_00210 1.2e-145 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIIMCIKM_00211 3e-232 secD U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIIMCIKM_00212 5.7e-22 yrzD S Post-transcriptional regulator
MIIMCIKM_00213 3.3e-262 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIIMCIKM_00214 4.8e-27 yodI
MIIMCIKM_00215 8e-79 ycaP S membrane
MIIMCIKM_00216 1.6e-61 yrzE S Protein of unknown function (DUF3792)
MIIMCIKM_00217 3.9e-38 yajC U Preprotein translocase subunit YajC
MIIMCIKM_00218 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MIIMCIKM_00219 2e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MIIMCIKM_00220 6.3e-28 yrzS S Protein of unknown function (DUF2905)
MIIMCIKM_00221 1.6e-123 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MIIMCIKM_00222 7.8e-115 V FtsX-like permease family
MIIMCIKM_00223 2.5e-138 V ABC transporter
MIIMCIKM_00224 4.1e-57 ytrA K GntR family transcriptional regulator
MIIMCIKM_00225 1.1e-43 V ABC transporter, ATP-binding protein
MIIMCIKM_00226 2.2e-102 V ABC transporter, ATP-binding protein
MIIMCIKM_00227 1.3e-97 S ABC-2 family transporter protein
MIIMCIKM_00228 1.1e-178 gluQ 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIIMCIKM_00230 4.3e-153 bla 3.5.2.6 V beta-lactamase
MIIMCIKM_00231 0.0 blaR 3.5.2.6 KTV BlaR1 peptidase M56
MIIMCIKM_00232 3.9e-63 blaI K Penicillinase repressor
MIIMCIKM_00233 1.8e-144 aadD H KNTase C-terminal domain
MIIMCIKM_00234 1.1e-57 cadC K transcriptional
MIIMCIKM_00235 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MIIMCIKM_00236 1.7e-213 fadA 2.3.1.16 I Belongs to the thiolase family
MIIMCIKM_00237 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MIIMCIKM_00238 1.2e-225 EGP Major facilitator Superfamily
MIIMCIKM_00239 0.0 S Sugar transport-related sRNA regulator N-term
MIIMCIKM_00240 4.6e-128 S Glycosyltransferase like family
MIIMCIKM_00241 5.7e-139 3.5.1.104 G Polysaccharide deacetylase
MIIMCIKM_00243 6.4e-108 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MIIMCIKM_00244 2.4e-250 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MIIMCIKM_00245 3.8e-221 S protein conserved in bacteria
MIIMCIKM_00246 2.7e-21
MIIMCIKM_00247 2.5e-71 yugN S YugN-like family
MIIMCIKM_00248 3.5e-260 pgi 5.3.1.9 G Belongs to the GPI family
MIIMCIKM_00249 8.3e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MIIMCIKM_00250 3.1e-228 yugK C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MIIMCIKM_00251 1.2e-33 yuzA S Domain of unknown function (DUF378)
MIIMCIKM_00252 3.3e-52 J RNA binding protein (contains ribosomal protein S1 domain)
MIIMCIKM_00253 1.6e-205 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MIIMCIKM_00254 1.7e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MIIMCIKM_00255 3.9e-223 yugH 2.6.1.1 E Aminotransferase
MIIMCIKM_00256 3.1e-84 alaR K Transcriptional regulator
MIIMCIKM_00257 1.1e-86 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MIIMCIKM_00258 6.1e-146 yihY S Belongs to the UPF0761 family
MIIMCIKM_00259 1.9e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MIIMCIKM_00260 4e-232 S antiporter
MIIMCIKM_00261 1.9e-289 E COG0747 ABC-type dipeptide transport system, periplasmic component
MIIMCIKM_00264 3.4e-07
MIIMCIKM_00266 1.5e-07
MIIMCIKM_00271 5.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MIIMCIKM_00272 1.9e-121 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MIIMCIKM_00273 6.1e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MIIMCIKM_00274 7.7e-222 ybbR S protein conserved in bacteria
MIIMCIKM_00275 1.6e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIIMCIKM_00277 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MIIMCIKM_00278 4.2e-155 ybfI K AraC-like ligand binding domain
MIIMCIKM_00279 1.1e-40 S Protein of unknown function, DUF485
MIIMCIKM_00280 1.7e-263 actP S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIIMCIKM_00281 1.3e-64 ysdB S Sigma-w pathway protein YsdB
MIIMCIKM_00282 9.8e-205 ysdC G COG1363 Cellulase M and related proteins
MIIMCIKM_00283 2.1e-16
MIIMCIKM_00285 1.4e-30 sspI S Belongs to the SspI family
MIIMCIKM_00286 5.7e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIIMCIKM_00287 2e-194 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MIIMCIKM_00288 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MIIMCIKM_00289 3.1e-34 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MIIMCIKM_00290 6e-86 cvpA S membrane protein, required for colicin V production
MIIMCIKM_00291 0.0 polX L COG1796 DNA polymerase IV (family X)
MIIMCIKM_00292 1.5e-18 bofA S Sigma-K factor-processing regulatory protein BofA
MIIMCIKM_00293 5.2e-31 S Protein of unknown function (DUF2508)
MIIMCIKM_00294 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIIMCIKM_00295 1.8e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MIIMCIKM_00296 1.2e-310 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIIMCIKM_00297 6.2e-117 K Sigma-70, region 4
MIIMCIKM_00298 4.8e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIIMCIKM_00299 3.6e-85 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MIIMCIKM_00300 3e-09
MIIMCIKM_00301 3e-298 gsiB_4 E COG0747 ABC-type dipeptide transport system, periplasmic component
MIIMCIKM_00302 1.4e-159 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_00303 5.9e-169 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_00304 7.4e-194 oppD P Belongs to the ABC transporter superfamily
MIIMCIKM_00305 1.1e-84 spoIIIAB S Stage III sporulation protein
MIIMCIKM_00306 1.2e-169 spoIIIAA S stage III sporulation protein AA
MIIMCIKM_00307 1.3e-35 yqhV S Protein of unknown function (DUF2619)
MIIMCIKM_00308 1e-50 S YfzA-like protein
MIIMCIKM_00309 1.1e-98 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MIIMCIKM_00310 3.2e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIIMCIKM_00311 2.4e-195 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MIIMCIKM_00312 1.8e-89 yqhR S Conserved membrane protein YqhR
MIIMCIKM_00313 2.7e-59
MIIMCIKM_00314 3.6e-168 yqhO S esterase of the alpha-beta hydrolase superfamily
MIIMCIKM_00315 1e-75 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MIIMCIKM_00316 3.1e-200 splB 4.1.99.14 L Spore photoproduct lyase
MIIMCIKM_00317 8.5e-159 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MIIMCIKM_00318 0.0 helD 3.6.4.12 L DNA helicase
MIIMCIKM_00319 6.2e-21 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
MIIMCIKM_00320 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIIMCIKM_00321 2.5e-85 M1-431 S Protein of unknown function (DUF1706)
MIIMCIKM_00322 5.1e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
MIIMCIKM_00323 5.8e-109 dhaL 2.7.1.121 S Dak2
MIIMCIKM_00324 1.1e-65 dhaM 2.7.1.121 S PTS system fructose IIA component
MIIMCIKM_00325 1.8e-24 S YfhD-like protein
MIIMCIKM_00326 4.8e-219 G Transmembrane secretion effector
MIIMCIKM_00327 2.9e-181 aph 2.7.11.1 S Phosphotransferase enzyme family
MIIMCIKM_00328 3.3e-70
MIIMCIKM_00329 2.2e-211 pbuG S permease
MIIMCIKM_00331 2.8e-257 S proteins of the AP superfamily
MIIMCIKM_00332 1.7e-120 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
MIIMCIKM_00333 1.8e-75 fruD 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MIIMCIKM_00334 3.6e-157 kbaY 4.1.2.13, 4.1.2.40 G in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
MIIMCIKM_00335 4.5e-39
MIIMCIKM_00336 4.7e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MIIMCIKM_00340 2.4e-161 K LysR substrate binding domain
MIIMCIKM_00341 1.7e-104 ywqN S NAD(P)H-dependent
MIIMCIKM_00342 1.8e-72 fabH 2.3.1.180 I Chalcone and stilbene synthases, N-terminal domain
MIIMCIKM_00343 4.9e-117 K Transcriptional regulator
MIIMCIKM_00344 3e-199 V COG0842 ABC-type multidrug transport system, permease component
MIIMCIKM_00345 1.7e-142 V COG1131 ABC-type multidrug transport system, ATPase component
MIIMCIKM_00346 4e-80 M PFAM secretion protein HlyD family protein
MIIMCIKM_00347 6.3e-120 azlC E AzlC protein
MIIMCIKM_00348 1.1e-50 S Branched-chain amino acid transport protein (AzlD)
MIIMCIKM_00349 3.1e-245 araN G ABC transporter substrate-binding protein
MIIMCIKM_00350 3.9e-162 lacF G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_00351 4.9e-148 araQ P PFAM binding-protein-dependent transport systems inner membrane component
MIIMCIKM_00352 2.9e-26 mcbG S Pentapeptide repeats (9 copies)
MIIMCIKM_00353 2.5e-156 htpX O Belongs to the peptidase M48B family
MIIMCIKM_00354 1.5e-166 yjfC O Predicted Zn-dependent protease (DUF2268)
MIIMCIKM_00356 1.8e-156 3.5.1.28 M COG3103 SH3 domain protein
MIIMCIKM_00357 2.9e-69 E lactoylglutathione lyase activity
MIIMCIKM_00358 0.0 ltaS 2.7.8.20 M Sulfatase
MIIMCIKM_00359 2.2e-311 2.6.1.52 E Aminotransferase class-V
MIIMCIKM_00360 4.4e-92 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MIIMCIKM_00361 9.9e-106 V Beta-lactamase
MIIMCIKM_00362 1.8e-151 yfhB 5.3.3.17 S PhzF family
MIIMCIKM_00363 3.1e-65 S Protein of unknown function, DUF393
MIIMCIKM_00364 7.6e-191 S Oxidoreductase family, NAD-binding Rossmann fold
MIIMCIKM_00365 7.2e-172 3.2.2.21 K Cupin domain
MIIMCIKM_00366 2e-140 G Xylose isomerase-like TIM barrel
MIIMCIKM_00367 1.2e-210 S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_00368 5.6e-255 G Bacterial extracellular solute-binding protein
MIIMCIKM_00369 2.8e-171 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_00370 7.3e-155 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_00371 8.9e-144 G Xylose isomerase-like TIM barrel
MIIMCIKM_00372 2.8e-101 3.2.2.21 K AraC-like ligand binding domain
MIIMCIKM_00373 1.1e-211 S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_00374 4.7e-229 S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_00375 4.5e-171 3.2.2.21 K AraC-like ligand binding domain
MIIMCIKM_00376 5.2e-217 3.2.1.180 GH88 O Glycosyl Hydrolase Family 88
MIIMCIKM_00377 1.6e-163 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_00378 4.6e-149 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_00379 1.6e-257 G Bacterial extracellular solute-binding protein
MIIMCIKM_00381 6.9e-114 M Peptidase family M23
MIIMCIKM_00382 3.9e-62 S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIIMCIKM_00383 2.4e-19
MIIMCIKM_00384 1.5e-97 mutT 3.6.1.13, 3.6.1.55 L nUDIX hydrolase
MIIMCIKM_00385 8.7e-254 ywoF P Right handed beta helix region
MIIMCIKM_00386 2.9e-165 EG EamA-like transporter family
MIIMCIKM_00387 8.3e-105 K Bacterial regulatory proteins, tetR family
MIIMCIKM_00388 5.5e-57 S Family of unknown function (DUF5367)
MIIMCIKM_00389 9.4e-127 S KR domain
MIIMCIKM_00390 5e-10 K Transcriptional regulator
MIIMCIKM_00391 2.8e-88
MIIMCIKM_00392 9.7e-302 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MIIMCIKM_00394 5.6e-183 manA 5.3.1.8 G mannose-6-phosphate isomerase
MIIMCIKM_00395 3.3e-155 S Tetratricopeptide repeat
MIIMCIKM_00396 1.2e-141 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MIIMCIKM_00397 1.2e-233 yxiO S COG2270 Permeases of the major facilitator superfamily
MIIMCIKM_00398 1.1e-206 ysfB KT regulator
MIIMCIKM_00399 5.3e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
MIIMCIKM_00400 5.2e-256 glcF C Glycolate oxidase
MIIMCIKM_00401 2.3e-156 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MIIMCIKM_00402 1.2e-103 ssuC P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_00403 1.1e-175 ssuA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MIIMCIKM_00404 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIIMCIKM_00405 4.6e-79 yybA 2.3.1.57 K transcriptional
MIIMCIKM_00406 1.6e-07 S VanZ like family
MIIMCIKM_00407 1.8e-107 mrr V Restriction endonuclease
MIIMCIKM_00408 8.2e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MIIMCIKM_00409 1.1e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MIIMCIKM_00410 1.3e-223 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MIIMCIKM_00412 7.9e-85 ywpF S YwpF-like protein
MIIMCIKM_00413 3.7e-224 ymfD EGP Major facilitator Superfamily
MIIMCIKM_00414 5.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MIIMCIKM_00415 5.9e-138 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MIIMCIKM_00416 2.1e-137 ytlC P ABC transporter
MIIMCIKM_00417 7e-181 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MIIMCIKM_00418 8.3e-153 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MIIMCIKM_00419 6.6e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MIIMCIKM_00420 1.9e-253 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MIIMCIKM_00421 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIIMCIKM_00422 2.3e-56 nirD 1.7.1.15 P Nitrite reductase
MIIMCIKM_00423 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIIMCIKM_00424 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MIIMCIKM_00425 1.3e-221 nasA P COG2223 Nitrate nitrite transporter
MIIMCIKM_00426 6.2e-226 M Belongs to the BCCT transporter (TC 2.A.15) family
MIIMCIKM_00427 1.8e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MIIMCIKM_00428 1.3e-298 K Propionate catabolism activator
MIIMCIKM_00430 2.9e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MIIMCIKM_00431 5.5e-242 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
MIIMCIKM_00432 4.4e-183 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
MIIMCIKM_00433 2.5e-147 ybbH_2 K Transcriptional regulator
MIIMCIKM_00434 0.0 msbA2 3.6.3.44 V ABC transporter
MIIMCIKM_00435 9.4e-141 K helix_turn_helix, mercury resistance
MIIMCIKM_00436 2.3e-122 K helix_turn _helix lactose operon repressor
MIIMCIKM_00437 1.2e-49 yerC S protein conserved in bacteria
MIIMCIKM_00438 0.0 3.5.4.2 F adenine deaminase
MIIMCIKM_00439 7.1e-200 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MIIMCIKM_00441 1.4e-159 opuAC E glycine betaine
MIIMCIKM_00442 1e-148 proW P glycine betaine
MIIMCIKM_00443 9.4e-220 gbuA 3.6.3.32 E glycine betaine
MIIMCIKM_00444 2.2e-96 K Belongs to the GbsR family
MIIMCIKM_00446 3.8e-18
MIIMCIKM_00447 6.2e-21
MIIMCIKM_00448 5e-78 M nuclease activity
MIIMCIKM_00449 8.1e-227 pepR S Belongs to the peptidase M16 family
MIIMCIKM_00450 3.3e-36 ymxH S YlmC YmxH family
MIIMCIKM_00451 6.1e-160 spoVFA E subunit a
MIIMCIKM_00452 6.7e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MIIMCIKM_00453 3.6e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MIIMCIKM_00454 2.5e-220 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MIIMCIKM_00455 4.5e-163 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIIMCIKM_00456 4.6e-311 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MIIMCIKM_00457 3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MIIMCIKM_00458 1.9e-09 S YlzJ-like protein
MIIMCIKM_00459 9.3e-82 ftsK D Belongs to the FtsK SpoIIIE SftA family
MIIMCIKM_00460 1e-176 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MIIMCIKM_00461 4.5e-149 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MIIMCIKM_00462 1.4e-154 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIIMCIKM_00463 4.8e-163 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIIMCIKM_00464 1.2e-106 pgpB3 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MIIMCIKM_00465 5.1e-238 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIIMCIKM_00466 1.5e-77 S Putative small multi-drug export protein
MIIMCIKM_00467 2.6e-82 S DinB superfamily
MIIMCIKM_00468 2.9e-58 S Protein of unknown function (DUF1516)
MIIMCIKM_00469 8.9e-84 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MIIMCIKM_00470 8.7e-165 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MIIMCIKM_00471 3.8e-168 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MIIMCIKM_00472 3.1e-07 yeaO S Protein of unknown function, DUF488
MIIMCIKM_00474 6.3e-163 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MIIMCIKM_00475 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
MIIMCIKM_00476 1.2e-64 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MIIMCIKM_00477 2e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIIMCIKM_00478 2e-115 metI P COG2011 ABC-type metal ion transport system, permease component
MIIMCIKM_00479 9.7e-155 metQ P Belongs to the NlpA lipoprotein family
MIIMCIKM_00480 8.5e-96 S Cobalamin adenosyltransferase
MIIMCIKM_00481 1.5e-169 btuF P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MIIMCIKM_00482 6.4e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIIMCIKM_00483 7.1e-144 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MIIMCIKM_00484 1.2e-244 O assembly protein SufD
MIIMCIKM_00485 1.6e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MIIMCIKM_00486 4.5e-161 yvoD P COG0370 Fe2 transport system protein B
MIIMCIKM_00487 2.1e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MIIMCIKM_00488 1.8e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MIIMCIKM_00489 2.4e-48 yvlD S Membrane
MIIMCIKM_00491 1.9e-152 yvlB S Putative adhesin
MIIMCIKM_00492 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MIIMCIKM_00493 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MIIMCIKM_00494 4e-63 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MIIMCIKM_00495 8.4e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MIIMCIKM_00496 1.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MIIMCIKM_00497 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MIIMCIKM_00498 1.5e-172 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIIMCIKM_00499 3.3e-121 yjaU I carboxylic ester hydrolase activity
MIIMCIKM_00500 1.9e-158 5.1.3.2 GM RmlD substrate binding domain
MIIMCIKM_00501 1.1e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MIIMCIKM_00502 3e-13 comZ S ComZ
MIIMCIKM_00503 1.6e-149 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MIIMCIKM_00504 7.3e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIIMCIKM_00505 1.4e-10 S YrhC-like protein
MIIMCIKM_00506 1.3e-78 M1-460
MIIMCIKM_00507 1.8e-292 E Bacterial extracellular solute-binding proteins, family 5 Middle
MIIMCIKM_00508 5.9e-149 appF P ATPases associated with a variety of cellular activities
MIIMCIKM_00509 2.7e-143 oppD P Oligopeptide/dipeptide transporter, C-terminal region
MIIMCIKM_00510 1.1e-156 EP N-terminal TM domain of oligopeptide transport permease C
MIIMCIKM_00511 4.4e-153 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_00512 2.6e-109 arpR K Bacterial regulatory proteins, tetR family
MIIMCIKM_00513 0.0 pbp1A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MIIMCIKM_00514 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MIIMCIKM_00515 2.5e-169 yppC S Protein of unknown function (DUF2515)
MIIMCIKM_00517 9.2e-92 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MIIMCIKM_00518 2.7e-61 yppE S Bacterial domain of unknown function (DUF1798)
MIIMCIKM_00519 6e-15
MIIMCIKM_00520 5.6e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MIIMCIKM_00521 1.8e-98 pfpI 3.5.1.124 S DJ-1/PfpI family
MIIMCIKM_00522 2.1e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MIIMCIKM_00523 2.8e-54 yusE CO cell redox homeostasis
MIIMCIKM_00524 4.2e-77 yphP S Belongs to the UPF0403 family
MIIMCIKM_00525 1.1e-74 CO Thioredoxin-like
MIIMCIKM_00526 2.4e-138 T Calcineurin-like phosphoesterase superfamily domain
MIIMCIKM_00527 8.8e-148 ypgR C COG0694 Thioredoxin-like proteins and domains
MIIMCIKM_00528 5.5e-30
MIIMCIKM_00529 2.1e-85 ydbS S Bacterial PH domain
MIIMCIKM_00530 3.3e-259 ydbT S Membrane
MIIMCIKM_00531 4.7e-193 S Protein of unknown function (DUF2777)
MIIMCIKM_00532 3.4e-169
MIIMCIKM_00533 7e-128 telA P Belongs to the TelA family
MIIMCIKM_00534 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MIIMCIKM_00535 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MIIMCIKM_00536 5e-113 ypjP S YpjP-like protein
MIIMCIKM_00537 4.5e-39
MIIMCIKM_00538 4e-65 kapB G Kinase associated protein B
MIIMCIKM_00539 4.3e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIIMCIKM_00541 3.6e-88
MIIMCIKM_00542 3.2e-153 ycsE S hydrolases of the HAD superfamily
MIIMCIKM_00543 1.3e-20
MIIMCIKM_00544 1.4e-186 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MIIMCIKM_00545 8.4e-116 mhqD S Carboxylesterase
MIIMCIKM_00546 4.4e-92
MIIMCIKM_00547 3.4e-208 gerAC S Spore germination B3/ GerAC like, C-terminal
MIIMCIKM_00548 1.2e-189 gerAB E Spore germination protein
MIIMCIKM_00549 1.9e-259 gerAA EG Spore germination protein
MIIMCIKM_00550 0.0 pepF E oligoendopeptidase F
MIIMCIKM_00551 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MIIMCIKM_00552 1.4e-228 yprB L RNase_H superfamily
MIIMCIKM_00554 4.4e-95 ypsA S Belongs to the UPF0398 family
MIIMCIKM_00555 7.7e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MIIMCIKM_00556 1.7e-69 rnhA 3.1.26.4 L An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
MIIMCIKM_00557 1e-212 L Transposase
MIIMCIKM_00558 4.6e-39
MIIMCIKM_00559 2.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MIIMCIKM_00560 1e-187 S Oxidoreductase
MIIMCIKM_00561 0.0 2.2.1.6 EH Thiamine pyrophosphate enzyme, central domain
MIIMCIKM_00562 1e-63 pcaC 3.1.1.24, 4.1.1.44 S Carboxymuconolactone decarboxylase family
MIIMCIKM_00563 5e-63
MIIMCIKM_00564 6.2e-163 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MIIMCIKM_00566 2.7e-202 S Spore germination B3/ GerAC like, C-terminal
MIIMCIKM_00567 1.4e-201 E Spore germination protein
MIIMCIKM_00568 1.8e-273 P Spore gernimation protein GerA
MIIMCIKM_00569 2.6e-67 S Src homology 3 domains
MIIMCIKM_00570 4.8e-96 ogt 1.17.99.6, 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIIMCIKM_00571 8.6e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MIIMCIKM_00572 2e-100 S B3/4 domain
MIIMCIKM_00573 1.3e-81 dps P Belongs to the Dps family
MIIMCIKM_00574 1.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MIIMCIKM_00575 7e-125
MIIMCIKM_00576 8e-123 V ATPases associated with a variety of cellular activities
MIIMCIKM_00577 2.1e-61 yhcF K Transcriptional regulator
MIIMCIKM_00578 8.7e-131 S ABC-2 family transporter protein
MIIMCIKM_00579 2.8e-168 yhcH V ABC transporter, ATP-binding protein
MIIMCIKM_00580 8.2e-93 mepB S MepB protein
MIIMCIKM_00581 4e-150 rhaR2 K helix_turn_helix, arabinose operon control protein
MIIMCIKM_00582 1.5e-33 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
MIIMCIKM_00584 1.6e-102 3.5.1.124 S DJ-1/PfpI family
MIIMCIKM_00585 6.7e-156 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MIIMCIKM_00586 1.7e-208 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
MIIMCIKM_00587 8.4e-45 ptxB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
MIIMCIKM_00588 5.2e-184 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MIIMCIKM_00589 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
MIIMCIKM_00591 2.1e-63 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIIMCIKM_00592 1.5e-269 S Chlorophyllase enzyme
MIIMCIKM_00593 1.1e-124 G COG0395 ABC-type sugar transport system, permease component
MIIMCIKM_00594 1.8e-39 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIIMCIKM_00595 3.4e-252 ywfO S COG1078 HD superfamily phosphohydrolases
MIIMCIKM_00596 1.5e-91 ywgA 2.1.1.72, 3.1.21.3
MIIMCIKM_00598 5.6e-26 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MIIMCIKM_00599 6.4e-125 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MIIMCIKM_00600 9.4e-198 F S-adenosylhomocysteine deaminase activity
MIIMCIKM_00601 2.4e-98 ywhD S YwhD family
MIIMCIKM_00602 0.0 pepF E oligoendopeptidase F
MIIMCIKM_00603 1.7e-156 vipF 2.3.1.128 K Acetyltransferase (GNAT) domain
MIIMCIKM_00604 1.1e-264 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MIIMCIKM_00605 5.2e-54
MIIMCIKM_00607 5.5e-25
MIIMCIKM_00608 2.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIIMCIKM_00609 4.6e-169 ybaS 1.1.1.58 S Na -dependent transporter
MIIMCIKM_00610 4.6e-224 hipO3 3.5.1.47 S amidohydrolase
MIIMCIKM_00611 2.8e-252 S Membrane
MIIMCIKM_00612 1.2e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
MIIMCIKM_00613 3.9e-113 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MIIMCIKM_00614 0.0 malS 3.2.1.1 GH13 G Carbohydrate binding domain
MIIMCIKM_00615 1.4e-139 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
MIIMCIKM_00616 2.2e-57 S Dinitrogenase iron-molybdenum cofactor
MIIMCIKM_00617 1.4e-245 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIIMCIKM_00618 1.5e-92 ssuE 1.5.1.38 S FMN reductase
MIIMCIKM_00619 2.7e-163 ytlI K LysR substrate binding domain
MIIMCIKM_00620 1.4e-86 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MIIMCIKM_00621 1.2e-115 S membrane
MIIMCIKM_00622 1.8e-27 sspB S spore protein
MIIMCIKM_00623 1.3e-28 sspB S spore protein
MIIMCIKM_00624 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIIMCIKM_00626 4.7e-131
MIIMCIKM_00627 0.0
MIIMCIKM_00628 7.2e-53
MIIMCIKM_00629 1.7e-185 uxuA 4.2.1.8 G mannonate dehydratase activity
MIIMCIKM_00630 4.2e-189 S Tripartite tricarboxylate transporter family receptor
MIIMCIKM_00631 6.4e-263 S Tripartite tricarboxylate transporter TctA family
MIIMCIKM_00632 8.8e-82 S Tripartite tricarboxylate transporter TctB family
MIIMCIKM_00633 3.2e-259 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIIMCIKM_00634 4.5e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MIIMCIKM_00635 5e-90 2.3.1.128 J Acetyltransferase (GNAT) domain
MIIMCIKM_00636 7.7e-91
MIIMCIKM_00637 3.8e-145 Q ubiE/COQ5 methyltransferase family
MIIMCIKM_00638 1e-184 trpS 6.1.1.2 J Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MIIMCIKM_00639 1.7e-120 Q SAM-dependent methyltransferase
MIIMCIKM_00640 1.2e-144 ydfC EG EamA-like transporter family
MIIMCIKM_00641 2e-136 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIIMCIKM_00642 6e-114 panZ K Acetyltransferase (GNAT) domain
MIIMCIKM_00643 1.6e-66
MIIMCIKM_00644 1.2e-71 S Protein of unknown function (DUF2512)
MIIMCIKM_00645 4.1e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MIIMCIKM_00646 1.2e-85 2.3.1.128 J Acetyltransferase (GNAT) domain
MIIMCIKM_00647 1.5e-52 S PFAM Uncharacterised protein family UPF0150
MIIMCIKM_00648 5.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_00649 8.8e-164 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MIIMCIKM_00650 7.6e-154 ytmP 2.7.1.89 M Phosphotransferase
MIIMCIKM_00651 6.3e-14 S YtzH-like protein
MIIMCIKM_00652 6.9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MIIMCIKM_00653 5.7e-49 ytzB
MIIMCIKM_00654 3.6e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MIIMCIKM_00655 3.5e-91 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MIIMCIKM_00656 1.9e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MIIMCIKM_00657 3.8e-118 S Phosphotransferase system, EIIC
MIIMCIKM_00658 1e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MIIMCIKM_00659 2.5e-50 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
MIIMCIKM_00660 7.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIIMCIKM_00661 1.5e-44 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MIIMCIKM_00662 3.2e-123 yybG S Pentapeptide repeat-containing protein
MIIMCIKM_00663 1.4e-84 3.4.16.4 V Beta-lactamase
MIIMCIKM_00664 2.9e-66 cdd_2 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
MIIMCIKM_00665 1.1e-215 yeaN P COG2807 Cyanate permease
MIIMCIKM_00666 2.8e-120 K FCD
MIIMCIKM_00667 4.4e-121 ycbG K FCD
MIIMCIKM_00668 1.1e-104 K helix_turn_helix, Lux Regulon
MIIMCIKM_00669 7.2e-195 desK 2.7.13.3 T Histidine kinase
MIIMCIKM_00670 4e-221 G Transmembrane secretion effector
MIIMCIKM_00671 2.8e-282 T COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
MIIMCIKM_00672 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MIIMCIKM_00673 6.2e-249 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MIIMCIKM_00674 1.6e-185 pelB 4.2.2.2 G Amb_all
MIIMCIKM_00676 1.6e-283 S ABC transporter
MIIMCIKM_00677 5.9e-120 T protein histidine kinase activity
MIIMCIKM_00678 2.8e-270 S Protein of unknown function (DUF3298)
MIIMCIKM_00679 1.6e-148 tatD L hydrolase, TatD
MIIMCIKM_00680 2.3e-216 rpfB GH23 T protein conserved in bacteria
MIIMCIKM_00681 1.2e-115 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MIIMCIKM_00682 5.7e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MIIMCIKM_00683 1.3e-162 yabG S peptidase
MIIMCIKM_00684 1.2e-39 veg S protein conserved in bacteria
MIIMCIKM_00685 3.3e-25 sspF S DNA topological change
MIIMCIKM_00686 4.8e-165 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIIMCIKM_00687 1.7e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MIIMCIKM_00688 4.2e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MIIMCIKM_00689 1.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MIIMCIKM_00690 1.7e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MIIMCIKM_00691 5.3e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIIMCIKM_00692 2.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MIIMCIKM_00693 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MIIMCIKM_00694 3.1e-39 yabK S Peptide ABC transporter permease
MIIMCIKM_00695 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIIMCIKM_00696 1.2e-94 spoVT K stage V sporulation protein
MIIMCIKM_00697 1.3e-90 S Yip1 domain
MIIMCIKM_00698 7.2e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MIIMCIKM_00699 5.2e-89 S Yip1 domain
MIIMCIKM_00700 2.5e-273 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIIMCIKM_00701 7.7e-277 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MIIMCIKM_00702 9e-24 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MIIMCIKM_00703 5.1e-119 S hydrolase
MIIMCIKM_00704 7.8e-177 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIIMCIKM_00705 3e-87 2.3.1.128 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIIMCIKM_00706 2.4e-200 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MIIMCIKM_00707 6.9e-104 MA20_20865 3.6.1.27 S SNARE associated Golgi protein
MIIMCIKM_00708 6.7e-53 yabP S Sporulation protein YabP
MIIMCIKM_00709 1.7e-67 yabQ S spore cortex biosynthesis protein
MIIMCIKM_00710 1.6e-61 divIC D Septum formation initiator
MIIMCIKM_00711 3.3e-71 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MIIMCIKM_00713 3.1e-224 citM C Citrate transporter
MIIMCIKM_00714 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MIIMCIKM_00715 4.6e-129 yabS S protein containing a von Willebrand factor type A (vWA) domain
MIIMCIKM_00716 3.4e-177 KLT serine threonine protein kinase
MIIMCIKM_00717 5.7e-269 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MIIMCIKM_00718 1.8e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MIIMCIKM_00719 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIIMCIKM_00720 6.5e-142 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIIMCIKM_00721 1.7e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MIIMCIKM_00722 8.7e-173 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MIIMCIKM_00723 8.9e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIIMCIKM_00724 5.6e-109 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MIIMCIKM_00725 2.5e-155 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MIIMCIKM_00726 1e-148 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MIIMCIKM_00727 7.1e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MIIMCIKM_00728 1.3e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MIIMCIKM_00729 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIIMCIKM_00730 1.7e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MIIMCIKM_00731 3.3e-167 eutC 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
MIIMCIKM_00733 2.5e-115 yhcQ M Spore coat protein
MIIMCIKM_00734 2.3e-243 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MIIMCIKM_00735 3.8e-108 E Lysine exporter protein LysE YggA
MIIMCIKM_00736 1.1e-147 yjqC P Catalase
MIIMCIKM_00737 5.5e-25 S Domain of unknown function (DUF5082)
MIIMCIKM_00738 1.3e-36 S Family of unknown function (DUF5344)
MIIMCIKM_00739 0.0 S LXG domain of WXG superfamily
MIIMCIKM_00740 1.1e-59
MIIMCIKM_00741 9.2e-192 4.2.1.103 K DJ-1/PfpI family
MIIMCIKM_00742 1.6e-114 S Predicted membrane protein (DUF2306)
MIIMCIKM_00743 4e-209 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MIIMCIKM_00744 3e-78 S VanZ like family
MIIMCIKM_00745 8.1e-111 wrbA 1.6.5.2 S Belongs to the WrbA family
MIIMCIKM_00746 8.3e-93 2.3.1.128 K Acetyltransferase (GNAT) family
MIIMCIKM_00747 8.2e-137 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MIIMCIKM_00748 0.0 V SNF2 family N-terminal domain
MIIMCIKM_00749 3.5e-140 est 3.1.1.1 S Carboxylesterase
MIIMCIKM_00750 3.8e-138 S COG1647 Esterase lipase
MIIMCIKM_00751 1.6e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIIMCIKM_00752 7.1e-28 secG U Preprotein translocase subunit SecG
MIIMCIKM_00753 1.2e-79 yclD
MIIMCIKM_00754 4e-265 S Tripartite tricarboxylate transporter TctA family
MIIMCIKM_00755 1.3e-76 S Tripartite tricarboxylate transporter TctB family
MIIMCIKM_00756 5.8e-164 S Tripartite tricarboxylate transporter family receptor
MIIMCIKM_00757 1.7e-81 4.2.1.158 M Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
MIIMCIKM_00758 8e-39 yabA L Involved in initiation control of chromosome replication
MIIMCIKM_00759 4.4e-144 yaaT S stage 0 sporulation protein
MIIMCIKM_00760 9.7e-183 holB 2.7.7.7 L DNA polymerase III
MIIMCIKM_00761 1.1e-53 yaaQ S protein conserved in bacteria
MIIMCIKM_00762 1.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MIIMCIKM_00763 4.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MIIMCIKM_00765 9.2e-186 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MIIMCIKM_00766 6e-277 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MIIMCIKM_00767 2e-166 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MIIMCIKM_00768 4.8e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MIIMCIKM_00769 1.9e-231 S COG0457 FOG TPR repeat
MIIMCIKM_00770 1.2e-97 ypiB S Belongs to the UPF0302 family
MIIMCIKM_00771 1.2e-82 ypiF S Protein of unknown function (DUF2487)
MIIMCIKM_00772 7.4e-91 qcrA C Menaquinol-cytochrome c reductase
MIIMCIKM_00773 7.7e-123 petB C COG1290 Cytochrome b subunit of the bc complex
MIIMCIKM_00774 4.2e-149 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MIIMCIKM_00775 3.1e-110 ypjA S membrane
MIIMCIKM_00776 5.9e-182 argE 3.5.1.16 E Acetylornithine deacetylase
MIIMCIKM_00777 1.3e-125 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MIIMCIKM_00778 9.1e-195 pslL G Acyltransferase family
MIIMCIKM_00779 3.3e-161 3.13.1.3 P YhfZ C-terminal domain
MIIMCIKM_00780 4.2e-56 S PRD domain
MIIMCIKM_00781 1.2e-58 yhfU S Protein of unknown function DUF2620
MIIMCIKM_00782 1.6e-222 yhfT S Protein of unknown function
MIIMCIKM_00783 5e-173 php S Phosphotriesterase family
MIIMCIKM_00784 1e-204 2.9.1.1 E Cys/Met metabolism PLP-dependent enzyme
MIIMCIKM_00785 2.3e-65 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MIIMCIKM_00786 1.1e-197 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MIIMCIKM_00787 5.5e-150 rfbD 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MIIMCIKM_00788 2e-40 exoZ I Acyltransferase family
MIIMCIKM_00789 4.3e-32 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MIIMCIKM_00790 7.9e-30 S Domain of unknown function (DUF3784)
MIIMCIKM_00792 5.2e-110 K intracellular protease amidase
MIIMCIKM_00793 4e-112 1.6.5.2 S NADPH-dependent FMN reductase
MIIMCIKM_00794 4e-65 ytcD5 K Transcriptional regulator
MIIMCIKM_00797 9.7e-39
MIIMCIKM_00799 1.5e-52 K Transcriptional regulator
MIIMCIKM_00800 1.8e-125
MIIMCIKM_00801 6.1e-96
MIIMCIKM_00802 7.5e-58
MIIMCIKM_00803 2.6e-299 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MIIMCIKM_00804 1.6e-154 licT K antiterminator
MIIMCIKM_00805 3.5e-269 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MIIMCIKM_00806 3.7e-176 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MIIMCIKM_00807 1.5e-87 M Protein of unknown function (DUF1541)
MIIMCIKM_00808 7.3e-71
MIIMCIKM_00809 2.8e-296 expZ S ABC transporter
MIIMCIKM_00810 2.3e-43 yabB 2.1.1.223 S Conserved hypothetical protein 95
MIIMCIKM_00811 1.5e-42 yazA L endonuclease containing a URI domain
MIIMCIKM_00812 7e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MIIMCIKM_00813 1.1e-43 abrB K COG2002 Regulators of stationary sporulation gene expression
MIIMCIKM_00814 1.9e-175 S NurA
MIIMCIKM_00815 0.0 S Domain of unknown function DUF87
MIIMCIKM_00816 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIIMCIKM_00817 2e-82 K DNA-binding transcription factor activity
MIIMCIKM_00818 2e-92 yfkM 3.5.1.124 S protease
MIIMCIKM_00819 1.3e-73 moaC 4.6.1.17 H MoaC family
MIIMCIKM_00820 6.3e-94 bioY S BioY family
MIIMCIKM_00821 1e-170 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MIIMCIKM_00822 7e-130 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MIIMCIKM_00823 1.2e-152 spoIVFB S Stage IV sporulation protein
MIIMCIKM_00824 2.2e-271 rng J ribonuclease, Rne Rng family
MIIMCIKM_00825 2.2e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
MIIMCIKM_00826 1.8e-56 ysxB J ribosomal protein
MIIMCIKM_00827 1.7e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MIIMCIKM_00828 4e-44 abrB K SpoVT / AbrB like domain
MIIMCIKM_00829 1.2e-213 Q COG1228 Imidazolonepropionase and related amidohydrolases
MIIMCIKM_00831 1.1e-118 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
MIIMCIKM_00832 1.9e-214 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MIIMCIKM_00833 5.1e-133 S Peptidase C26
MIIMCIKM_00834 8e-274 nylA 3.5.1.4 J Belongs to the amidase family
MIIMCIKM_00835 2.1e-82 S DinB family
MIIMCIKM_00836 7.4e-169 pstS P Phosphate
MIIMCIKM_00837 6.4e-160 pstC P probably responsible for the translocation of the substrate across the membrane
MIIMCIKM_00838 9.4e-161 pstA P Phosphate transport system permease
MIIMCIKM_00839 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MIIMCIKM_00840 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MIIMCIKM_00841 6.5e-111 phoU P Plays a role in the regulation of phosphate uptake
MIIMCIKM_00842 7.1e-62
MIIMCIKM_00843 0.0 addB 3.6.4.12 L exonuclease activity
MIIMCIKM_00844 0.0 recB 3.1.11.5, 3.1.12.1, 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MIIMCIKM_00845 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MIIMCIKM_00846 8e-73 cheW NT chemotaxis
MIIMCIKM_00847 0.0 asnB 6.3.5.4 E Asparagine synthase
MIIMCIKM_00848 2.3e-47 S IDEAL
MIIMCIKM_00849 0.0 wapA M COG3209 Rhs family protein
MIIMCIKM_00851 1.7e-91 wapA M COG3209 Rhs family protein
MIIMCIKM_00852 2.2e-70 yxxG
MIIMCIKM_00854 1.5e-155 ykgA E Amidinotransferase
MIIMCIKM_00855 7.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MIIMCIKM_00856 7.5e-92
MIIMCIKM_00857 9.9e-64 ytwF P Sulfurtransferase
MIIMCIKM_00858 2.3e-41
MIIMCIKM_00859 5.6e-149 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MIIMCIKM_00860 2.8e-146 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MIIMCIKM_00861 1.9e-30 ipi S Intracellular proteinase inhibitor
MIIMCIKM_00863 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MIIMCIKM_00864 9.2e-231 ywqB S zinc ion binding
MIIMCIKM_00865 2.2e-108
MIIMCIKM_00866 1.8e-78 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) domain
MIIMCIKM_00867 9.5e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MIIMCIKM_00868 7.4e-166 ctaG S cytochrome c oxidase
MIIMCIKM_00869 2.7e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MIIMCIKM_00870 2.1e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MIIMCIKM_00871 0.0 fadF C COG0247 Fe-S oxidoreductase
MIIMCIKM_00872 2.7e-216 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
MIIMCIKM_00873 3.3e-155 hbdA 1.1.1.157 I Dehydrogenase
MIIMCIKM_00874 2.9e-207 mmgC I acyl-CoA dehydrogenase
MIIMCIKM_00875 1.7e-108 kstR2_2 K Transcriptional regulator
MIIMCIKM_00876 1.4e-63 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MIIMCIKM_00878 2.9e-187 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MIIMCIKM_00879 4.9e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MIIMCIKM_00880 1.1e-130 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MIIMCIKM_00881 4.9e-87 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MIIMCIKM_00882 3.2e-181 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MIIMCIKM_00883 2.7e-311 ydiF S ABC transporter
MIIMCIKM_00884 2.3e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MIIMCIKM_00885 1.4e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MIIMCIKM_00887 8.1e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MIIMCIKM_00888 5.4e-289 prdR KT Transcriptional regulator
MIIMCIKM_00889 1.2e-171 putA E Proline dehydrogenase
MIIMCIKM_00890 1.1e-150 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MIIMCIKM_00891 2.2e-74 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIIMCIKM_00892 5.8e-121 spo0J K Belongs to the ParB family
MIIMCIKM_00893 3.7e-218 sufS 2.8.1.7, 4.4.1.16 E Aminotransferase class-V
MIIMCIKM_00894 1.1e-115 yyaC S Sporulation protein YyaC
MIIMCIKM_00895 7.6e-175 yyaD S Membrane
MIIMCIKM_00896 1.8e-27 yyzM S protein conserved in bacteria
MIIMCIKM_00897 1e-193 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MIIMCIKM_00898 6.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
MIIMCIKM_00899 1.6e-58 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MIIMCIKM_00900 8.7e-281 lipA1 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MIIMCIKM_00901 1e-284 K transcriptional antiterminator
MIIMCIKM_00902 1.2e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MIIMCIKM_00903 0.0 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MIIMCIKM_00904 4.3e-277 S LXG domain of WXG superfamily
MIIMCIKM_00907 2.8e-07
MIIMCIKM_00908 4.8e-07
MIIMCIKM_00909 9.3e-121 lolD V ABC transporter
MIIMCIKM_00910 1.6e-307 sdcS P Sodium:sulfate symporter transmembrane region
MIIMCIKM_00911 3e-122 T COG4565 Response regulator of citrate malate metabolism
MIIMCIKM_00912 6.7e-181 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MIIMCIKM_00913 3.8e-10
MIIMCIKM_00914 4e-40 S Protein of unknown function (DUF2642)
MIIMCIKM_00915 3.5e-153 manA3 3.2.1.78 GH26 G Endoglucanase
MIIMCIKM_00916 2.4e-250 G Bacterial extracellular solute-binding protein
MIIMCIKM_00917 2.6e-169 P COG0395 ABC-type sugar transport system, permease component
MIIMCIKM_00918 8.1e-144 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_00919 1.4e-110 ypbG 2.7.1.2 GK ROK family
MIIMCIKM_00920 2e-83
MIIMCIKM_00921 2.1e-67 yueI S Protein of unknown function (DUF1694)
MIIMCIKM_00922 1.3e-268 spoVAF EG Bacillus/Clostridium GerA spore germination protein
MIIMCIKM_00923 9.4e-297 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MIIMCIKM_00925 3.9e-168 nhaC C Na H antiporter
MIIMCIKM_00926 6.4e-58 K MerR, DNA binding
MIIMCIKM_00927 5.2e-55 2.7.1.48, 3.1.3.18 F uridine kinase
MIIMCIKM_00928 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
MIIMCIKM_00929 1.6e-42 ulaB_1 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MIIMCIKM_00930 5.1e-209 gatD 1.1.1.14 C Alcohol dehydrogenase GroES-like domain
MIIMCIKM_00931 7.3e-21
MIIMCIKM_00932 7.5e-194 gutB 1.1.1.1, 1.1.1.14 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MIIMCIKM_00933 9.4e-215 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
MIIMCIKM_00934 1.3e-42 gatB_1 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MIIMCIKM_00935 4e-81 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MIIMCIKM_00936 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
MIIMCIKM_00937 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MIIMCIKM_00938 2.1e-199
MIIMCIKM_00939 7.7e-109 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MIIMCIKM_00940 5e-176 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MIIMCIKM_00941 4.6e-107 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MIIMCIKM_00942 5.6e-95 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
MIIMCIKM_00943 3e-200 MA20_17100 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MIIMCIKM_00944 1.6e-85 G Tripartite ATP-independent periplasmic transporters, DctQ component
MIIMCIKM_00945 1.3e-182 dctP_1 G Bacterial extracellular solute-binding protein, family 7
MIIMCIKM_00946 2.9e-182 kdgR K transcriptional
MIIMCIKM_00947 1.5e-52 K Transcriptional regulator PadR-like family
MIIMCIKM_00948 1.1e-74
MIIMCIKM_00949 6.2e-76
MIIMCIKM_00950 1.2e-199 frvX 3.2.1.4 GH5,GH9 G M42 glutamyl aminopeptidase
MIIMCIKM_00951 3.9e-44 S Membrane
MIIMCIKM_00952 3.4e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
MIIMCIKM_00953 9.1e-166 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MIIMCIKM_00954 5e-145 tagG GM Transport permease protein
MIIMCIKM_00955 6.9e-147 S GNAT acetyltransferase
MIIMCIKM_00956 0.0 3.6.3.8 P COG0474 Cation transport ATPase
MIIMCIKM_00957 1.2e-296 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MIIMCIKM_00958 1.4e-24
MIIMCIKM_00959 2.1e-306 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MIIMCIKM_00960 3.1e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MIIMCIKM_00961 5.1e-111 modB P COG4149 ABC-type molybdate transport system, permease component
MIIMCIKM_00962 2.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIIMCIKM_00963 1.8e-190 vraS 2.7.13.3 T Histidine kinase
MIIMCIKM_00964 5.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MIIMCIKM_00965 1.4e-105
MIIMCIKM_00967 1.9e-30
MIIMCIKM_00968 9.7e-117 4.4.1.3, 5.3.1.15 S Cupin
MIIMCIKM_00969 0.0 DSE4 M glycoside hydrolase family 81
MIIMCIKM_00970 4.4e-194 purR11 K helix_turn _helix lactose operon repressor
MIIMCIKM_00971 4.1e-127 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MIIMCIKM_00972 1.3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MIIMCIKM_00973 1.7e-173 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_00974 1.7e-179 K WYL domain
MIIMCIKM_00975 1.8e-113 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIIMCIKM_00976 3.9e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MIIMCIKM_00977 7.8e-150 czcD P COG1230 Co Zn Cd efflux system component
MIIMCIKM_00978 5.7e-49 czrA K transcriptional
MIIMCIKM_00979 1.7e-165 gltC K Transcriptional regulator
MIIMCIKM_00980 3.2e-264 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MIIMCIKM_00981 8.8e-139 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MIIMCIKM_00982 3.5e-177 P ABC transporter substrate-binding protein
MIIMCIKM_00983 3.2e-203 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MIIMCIKM_00984 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MIIMCIKM_00985 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MIIMCIKM_00986 1e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MIIMCIKM_00987 3.4e-94 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIIMCIKM_00988 1.2e-199 adhA 1.1.1.1 C alcohol dehydrogenase
MIIMCIKM_00989 6e-274 T Sigma-54 interaction domain
MIIMCIKM_00990 3.2e-278 cckA 2.7.13.3 T GAF domain
MIIMCIKM_00991 1.7e-12
MIIMCIKM_00992 1.2e-149 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
MIIMCIKM_00993 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIIMCIKM_00994 1.2e-185 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_00995 4.3e-93 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
MIIMCIKM_00996 1.1e-86 L RAMP superfamily
MIIMCIKM_00997 4e-19
MIIMCIKM_00998 1.8e-78 L RAMP superfamily
MIIMCIKM_00999 1.1e-22 L RAMP superfamily
MIIMCIKM_01000 8.6e-125
MIIMCIKM_01001 8.3e-38 ptsH G PTS HPr component phosphorylation site
MIIMCIKM_01002 9.6e-236 thrA E SAF
MIIMCIKM_01003 9.8e-68 K Glucitol operon activator protein (GutM)
MIIMCIKM_01004 5.6e-89 srlA G PTS system enzyme II sorbitol-specific factor
MIIMCIKM_01005 1.2e-183 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
MIIMCIKM_01006 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MIIMCIKM_01008 1.2e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MIIMCIKM_01009 5.9e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MIIMCIKM_01010 8.3e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIIMCIKM_01011 3e-07 lig1
MIIMCIKM_01012 1.3e-132 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
MIIMCIKM_01013 4.8e-233 legA 3.5.1.2 O Peptidase family M48
MIIMCIKM_01014 3.4e-247 speA 4.1.1.19 E Arginine
MIIMCIKM_01015 5.3e-33 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01016 9.2e-158 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01017 4.9e-303 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MIIMCIKM_01018 3.7e-243 G Bacterial extracellular solute-binding protein
MIIMCIKM_01019 1.6e-117 ktrA P COG0569 K transport systems, NAD-binding component
MIIMCIKM_01020 0.0 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MIIMCIKM_01021 1.8e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MIIMCIKM_01022 3.9e-187 purR15 K Bacterial regulatory proteins, lacI family
MIIMCIKM_01023 2.9e-201 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MIIMCIKM_01024 4.9e-77 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIIMCIKM_01025 5.8e-146 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MIIMCIKM_01026 5.4e-92 ywjG S Domain of unknown function (DUF2529)
MIIMCIKM_01027 2.5e-59 spo0F T response regulator
MIIMCIKM_01028 2.7e-160 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MIIMCIKM_01029 1.7e-114 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MIIMCIKM_01030 3.5e-209 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIIMCIKM_01031 7e-178 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MIIMCIKM_01032 1.3e-235 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIIMCIKM_01033 3.8e-40 rpmE2 J Ribosomal protein L31
MIIMCIKM_01034 2.9e-110 tdk 2.7.1.21 F thymidine kinase
MIIMCIKM_01035 1.9e-74
MIIMCIKM_01036 1.7e-259 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MIIMCIKM_01037 8.6e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MIIMCIKM_01038 7.8e-160 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MIIMCIKM_01039 1.4e-113 spoIIR S stage II sporulation protein R
MIIMCIKM_01040 4.4e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MIIMCIKM_01041 2.3e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MIIMCIKM_01042 1.6e-61 S Regulator of ribonuclease activity B
MIIMCIKM_01043 8.7e-93 mntP P Probably functions as a manganese efflux pump
MIIMCIKM_01044 3.1e-63 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIIMCIKM_01045 7.6e-151 mcpA NT Chemotaxis
MIIMCIKM_01046 4.9e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MIIMCIKM_01047 5.9e-97 ywlG S Belongs to the UPF0340 family
MIIMCIKM_01048 6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MIIMCIKM_01049 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIIMCIKM_01050 4.6e-90 panZ K -acetyltransferase
MIIMCIKM_01051 0.0 vpr O Belongs to the peptidase S8 family
MIIMCIKM_01052 1.4e-23 atpI S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
MIIMCIKM_01053 7.3e-12 S ATP synthase I chain
MIIMCIKM_01054 2.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
MIIMCIKM_01055 1.4e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIIMCIKM_01056 1.3e-31 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MIIMCIKM_01057 6.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIIMCIKM_01058 1.7e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MIIMCIKM_01059 9.2e-153 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MIIMCIKM_01060 4.2e-264 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MIIMCIKM_01061 7e-55 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MIIMCIKM_01062 1.5e-21 ywmB S TATA-box binding
MIIMCIKM_01063 2.6e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIIMCIKM_01064 4.3e-189 spoIID D Stage II sporulation protein D
MIIMCIKM_01065 3.4e-131 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MIIMCIKM_01066 1.1e-53 sugE P Multidrug resistance protein
MIIMCIKM_01067 1.9e-47 ykkD P Multidrug resistance protein
MIIMCIKM_01068 3.6e-45 spoIIID K Stage III sporulation protein D
MIIMCIKM_01069 1.6e-180 mbl D Rod shape-determining protein
MIIMCIKM_01070 1.5e-141 flhO N flagellar basal body
MIIMCIKM_01071 8.7e-142 flhP N flagellar basal body
MIIMCIKM_01072 1.2e-61 epuA S DNA-directed RNA polymerase subunit beta
MIIMCIKM_01073 7.7e-275 P Spore gernimation protein GerA
MIIMCIKM_01074 2.7e-197 E Spore germination protein
MIIMCIKM_01075 1.4e-195 S Spore germination B3/ GerAC like, C-terminal
MIIMCIKM_01076 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MIIMCIKM_01077 6.6e-147 estA S Putative esterase
MIIMCIKM_01078 2.7e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MIIMCIKM_01079 4.7e-272 pip S YhgE Pip N-terminal domain protein
MIIMCIKM_01080 1.7e-96 speG_2 2.3.1.57 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MIIMCIKM_01081 2.5e-86 yisT S DinB family
MIIMCIKM_01082 7.2e-74 Q N-acetyltransferase
MIIMCIKM_01083 7.7e-55 rplI J binds to the 23S rRNA
MIIMCIKM_01084 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MIIMCIKM_01085 1.7e-149 yybS S membrane
MIIMCIKM_01087 1.2e-213 megL 2.5.1.48, 2.5.1.49, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
MIIMCIKM_01088 6.9e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIIMCIKM_01089 6e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIIMCIKM_01090 1.3e-120 sapB S MgtC SapB transporter
MIIMCIKM_01092 6.1e-194 T Histidine kinase
MIIMCIKM_01093 3.5e-106 KT LuxR family transcriptional regulator
MIIMCIKM_01094 9.5e-12 KT LuxR family transcriptional regulator
MIIMCIKM_01095 1.7e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MIIMCIKM_01096 1e-125 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MIIMCIKM_01097 2.8e-78 queD 4.1.2.50, 4.2.3.12 H synthase
MIIMCIKM_01098 3.5e-128 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MIIMCIKM_01099 9e-89 Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MIIMCIKM_01100 6.8e-138 ygaJ E Belongs to the peptidase S51 family
MIIMCIKM_01101 1.1e-163 S Alpha beta hydrolase
MIIMCIKM_01102 3.6e-177 yjiA S Cobalamin biosynthesis protein CobW
MIIMCIKM_01103 9.5e-297 ywjA V ABC transporter
MIIMCIKM_01104 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MIIMCIKM_01105 7e-98 S DinB superfamily
MIIMCIKM_01106 4.8e-159 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MIIMCIKM_01107 6e-168 speB 3.5.3.11 E Belongs to the arginase family
MIIMCIKM_01108 1e-75 ywiB S protein conserved in bacteria
MIIMCIKM_01110 4.4e-152 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MIIMCIKM_01111 1.4e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MIIMCIKM_01112 6.4e-67 phaG P Na+/H+ antiporter subunit
MIIMCIKM_01113 3.1e-38 phaF P Multiple resistance and pH regulation protein F (MrpF / PhaF)
MIIMCIKM_01114 2.8e-82 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIIMCIKM_01115 5.3e-41 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MIIMCIKM_01116 3.9e-99 mreB D Rod shape-determining protein MreB
MIIMCIKM_01117 2.1e-160 mreC M Involved in formation and maintenance of cell shape
MIIMCIKM_01118 8.8e-74 mreD M shape-determining protein
MIIMCIKM_01119 2.3e-122 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MIIMCIKM_01120 1.6e-140 minD D Belongs to the ParA family
MIIMCIKM_01121 1.4e-203 argS 6.1.1.19 J Arginyl-tRNA synthetase
MIIMCIKM_01122 2.3e-73 yqgC S protein conserved in bacteria
MIIMCIKM_01123 2.8e-224 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MIIMCIKM_01124 2.5e-97 yrkC G Cupin domain
MIIMCIKM_01125 5e-60 Q ubiE/COQ5 methyltransferase family
MIIMCIKM_01126 8e-94 yokH G SMI1 / KNR4 family
MIIMCIKM_01127 1.8e-32 ydfJ S drug exporters of the RND superfamily
MIIMCIKM_01128 5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MIIMCIKM_01129 7.4e-269 sufB O FeS cluster assembly
MIIMCIKM_01130 3.5e-241 aceA 4.1.3.1 C Isocitrate lyase
MIIMCIKM_01131 5.8e-17 S YhfH-like protein
MIIMCIKM_01132 1e-51 licT K transcriptional antiterminator
MIIMCIKM_01133 5.9e-41 3.2.1.86 GT1 G beta-glucosidase activity
MIIMCIKM_01134 6.4e-139 bioC_2 Q Methyltransferase domain
MIIMCIKM_01135 3.5e-188 gpr C Aldo/keto reductase family
MIIMCIKM_01136 9.3e-147 K AraC family transcriptional regulator
MIIMCIKM_01137 1.1e-181 P Periplasmic binding protein
MIIMCIKM_01138 3.4e-168 kka S Phosphotransferase enzyme family
MIIMCIKM_01139 4e-41 S Family of unknown function (DUF5344)
MIIMCIKM_01140 4.6e-232 S LXG domain of WXG superfamily
MIIMCIKM_01141 1.6e-46
MIIMCIKM_01142 3.6e-148
MIIMCIKM_01143 7.2e-48
MIIMCIKM_01144 1.2e-64 S Domain of unknown function (DUF5082)
MIIMCIKM_01145 1.7e-167 yunF S Protein of unknown function DUF72
MIIMCIKM_01146 1e-140 yunE S membrane transporter protein
MIIMCIKM_01147 1.1e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MIIMCIKM_01148 1.2e-49 yunC S Domain of unknown function (DUF1805)
MIIMCIKM_01149 1.5e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MIIMCIKM_01150 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MIIMCIKM_01151 4.6e-140 yunB S Sporulation protein YunB (Spo_YunB)
MIIMCIKM_01152 3.4e-295 nhaC C Na+/H+ antiporter family
MIIMCIKM_01153 5.5e-205 lytH M Peptidase, M23
MIIMCIKM_01154 1.6e-174 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MIIMCIKM_01155 1e-93 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIIMCIKM_01156 3.7e-50 yutD S protein conserved in bacteria
MIIMCIKM_01157 6e-44
MIIMCIKM_01158 1.9e-77 yutE S Protein of unknown function DUF86
MIIMCIKM_01159 1.2e-135 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MIIMCIKM_01160 4.6e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MIIMCIKM_01161 7.5e-210 yutH S Spore coat protein
MIIMCIKM_01162 1.9e-237 hom 1.1.1.3 E homoserine dehydrogenase
MIIMCIKM_01163 8.9e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MIIMCIKM_01164 7e-164 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MIIMCIKM_01165 9.7e-36 yutI O COG0694 Thioredoxin-like proteins and domains
MIIMCIKM_01166 1.7e-51 yuzD S protein conserved in bacteria
MIIMCIKM_01167 0.0 yutJ 1.6.99.3 C NADH dehydrogenase
MIIMCIKM_01168 7.6e-41 yuzB S Belongs to the UPF0349 family
MIIMCIKM_01169 1.4e-42
MIIMCIKM_01170 8.7e-164 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MIIMCIKM_01171 6.7e-209 mqnE 1.21.98.1, 2.5.1.120, 2.5.1.77 H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MIIMCIKM_01172 7.6e-09 S Spo0E like sporulation regulatory protein
MIIMCIKM_01173 2.9e-60 erpA S Belongs to the HesB IscA family
MIIMCIKM_01174 3.3e-110 yecS P COG0765 ABC-type amino acid transport system, permease component
MIIMCIKM_01175 1.6e-154 yckB ET Belongs to the bacterial solute-binding protein 3 family
MIIMCIKM_01176 1.5e-308 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MIIMCIKM_01177 0.0 mtlR K transcriptional regulator, MtlR
MIIMCIKM_01178 3e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MIIMCIKM_01179 1.7e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MIIMCIKM_01180 2.1e-185 ycgT 1.18.1.2, 1.19.1.1 C reductase
MIIMCIKM_01181 4.4e-230 yumB 1.6.99.3 C NADH dehydrogenase
MIIMCIKM_01182 1.5e-47 yuiB S Putative membrane protein
MIIMCIKM_01183 2.5e-112 yuiC S protein conserved in bacteria
MIIMCIKM_01184 7e-79 yuiD S protein conserved in bacteria
MIIMCIKM_01185 3.6e-282 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MIIMCIKM_01186 2.7e-45
MIIMCIKM_01187 3.8e-268 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIIMCIKM_01188 8.8e-170 dapAf2 4.3.3.7 EM Dihydrodipicolinate synthetase family
MIIMCIKM_01189 6.6e-79 MA20_15070 K FCD
MIIMCIKM_01190 1.3e-145 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MIIMCIKM_01191 5.1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MIIMCIKM_01192 5e-295 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Belongs to the FGGY kinase family
MIIMCIKM_01193 7.8e-21 S Protein of unknown function (DUF2564)
MIIMCIKM_01195 1.4e-53 hmoB 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MIIMCIKM_01196 6e-89 yufK S Family of unknown function (DUF5366)
MIIMCIKM_01197 1.1e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MIIMCIKM_01198 5.5e-169 yhbB S Putative amidase domain
MIIMCIKM_01199 5e-81 K Acetyltransferase (GNAT) domain
MIIMCIKM_01200 5.6e-64 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIIMCIKM_01202 5.1e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MIIMCIKM_01203 7.1e-60 mhqP S DoxX
MIIMCIKM_01204 1.1e-133 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MIIMCIKM_01205 3.1e-281 comEC S Competence protein ComEC
MIIMCIKM_01206 2.4e-07 S YqzM-like protein
MIIMCIKM_01207 5.1e-162 hgd 1.1.1.31, 1.1.1.60 I 3-hydroxyisobutyrate dehydrogenase
MIIMCIKM_01208 3.8e-41 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MIIMCIKM_01209 6e-73 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIIMCIKM_01210 3.9e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MIIMCIKM_01211 1.7e-187 cytR 5.1.1.1 K LacI family transcriptional regulator
MIIMCIKM_01212 2.9e-232 preA 1.3.1.1 CF dihydroorotate dehydrogenase
MIIMCIKM_01213 9.9e-166 gltD 1.3.1.1 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MIIMCIKM_01215 4.2e-121 msmF3 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01216 1.8e-234 msmE7 G Bacterial extracellular solute-binding protein
MIIMCIKM_01217 5.2e-136 bceA V ABC transporter, ATP-binding protein
MIIMCIKM_01218 0.0 bceB V ABC transporter (permease)
MIIMCIKM_01219 9.9e-208 gerKC S Spore germination B3/ GerAC like, C-terminal
MIIMCIKM_01220 1.8e-193 gerKB E Spore germination protein
MIIMCIKM_01221 9.6e-256 gerKA EG Spore germination protein
MIIMCIKM_01222 5e-199
MIIMCIKM_01223 8.1e-179 ectD 1.14.11.55 Q Phytanoyl-CoA dioxygenase (PhyH)
MIIMCIKM_01224 5.7e-299 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MIIMCIKM_01225 2.3e-176 feuA P Iron-uptake system-binding protein
MIIMCIKM_01226 1.1e-181 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIIMCIKM_01227 1.8e-184 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIIMCIKM_01228 1.8e-158 besA S Putative esterase
MIIMCIKM_01229 1.6e-246 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MIIMCIKM_01230 3.4e-126 tcpP 2.7.11.1 KT Forkhead associated domain
MIIMCIKM_01231 1.7e-159 3.5.2.6 V beta-lactamase
MIIMCIKM_01232 2.5e-139 S Nucleotidyltransferase domain
MIIMCIKM_01233 3.9e-243 hemAT NT chemotaxis protein
MIIMCIKM_01234 1e-187 K helix_turn _helix lactose operon repressor
MIIMCIKM_01235 7.2e-155 dkgB S Aldo/keto reductase family
MIIMCIKM_01236 9.3e-178 fhuD P ABC transporter
MIIMCIKM_01237 1.1e-144 K Helix-turn-helix domain
MIIMCIKM_01238 4.2e-59 S Ketosteroid isomerase-related protein
MIIMCIKM_01239 1.8e-187 MA20_22185 K Transcriptional regulator, LacI family
MIIMCIKM_01240 6e-185 S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_01241 1.8e-234 cycB_1 G Bacterial extracellular solute-binding protein
MIIMCIKM_01242 1.1e-164 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01243 2.9e-143 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01244 2.1e-190 G Xylose isomerase
MIIMCIKM_01245 9.5e-156 S Membrane transport protein
MIIMCIKM_01247 9e-97 K response regulator
MIIMCIKM_01248 6.4e-58
MIIMCIKM_01249 8.5e-21
MIIMCIKM_01250 7.4e-86 M1-1022 1.8.5.2 S DoxX
MIIMCIKM_01251 7.7e-269 murE 6.3.2.13 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIIMCIKM_01252 2.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MIIMCIKM_01253 1.6e-103 K Bacterial regulatory proteins, tetR family
MIIMCIKM_01254 1.8e-122 yqeB
MIIMCIKM_01255 4.2e-46 K PadR family transcriptional regulator
MIIMCIKM_01256 1.8e-75 V (ABC) transporter
MIIMCIKM_01257 1.6e-165 V VanW like protein
MIIMCIKM_01260 5.4e-126 yoqW S Belongs to the SOS response-associated peptidase family
MIIMCIKM_01261 5.8e-180 isp O Belongs to the peptidase S8 family
MIIMCIKM_01262 2.9e-171 yjlA EG Putative multidrug resistance efflux transporter
MIIMCIKM_01263 1e-268
MIIMCIKM_01264 4.6e-200 sstT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIIMCIKM_01265 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
MIIMCIKM_01266 2.6e-61 ytpQ S Belongs to the UPF0354 family
MIIMCIKM_01267 7.7e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MIIMCIKM_01268 7e-33
MIIMCIKM_01270 2.5e-135 yphF
MIIMCIKM_01272 2.8e-17 S Stage VI sporulation protein F
MIIMCIKM_01273 2.3e-287 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIIMCIKM_01274 1.1e-167 mviM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MIIMCIKM_01275 2.5e-23 C 4Fe-4S binding domain
MIIMCIKM_01276 4.4e-71 argH 4.3.2.1 E argininosuccinate lyase
MIIMCIKM_01278 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_01279 5.4e-65
MIIMCIKM_01280 8e-210 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MIIMCIKM_01281 5.6e-129 ytkL S Belongs to the UPF0173 family
MIIMCIKM_01283 6.7e-240 ytoI K transcriptional regulator containing CBS domains
MIIMCIKM_01284 4.6e-08 ytpI S YtpI-like protein
MIIMCIKM_01285 8.6e-173 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MIIMCIKM_01286 4.2e-89 ytrI
MIIMCIKM_01287 7.2e-53 ytrH S Sporulation protein YtrH
MIIMCIKM_01288 0.0 dnaE 2.7.7.7 L DNA polymerase
MIIMCIKM_01289 1.2e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MIIMCIKM_01290 9e-116 lutR_1 K helix_turn_helix gluconate operon transcriptional repressor
MIIMCIKM_01291 1.1e-153 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MIIMCIKM_01292 1.2e-180 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MIIMCIKM_01293 9.8e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MIIMCIKM_01294 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MIIMCIKM_01295 1.4e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MIIMCIKM_01296 6.7e-73 yeaL S UPF0756 membrane protein
MIIMCIKM_01297 5.2e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
MIIMCIKM_01298 2.6e-241 icd 1.1.1.42 C isocitrate
MIIMCIKM_01299 8.2e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MIIMCIKM_01300 8.9e-75 lrpC K helix_turn_helix ASNC type
MIIMCIKM_01301 4.4e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_01302 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MIIMCIKM_01303 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIIMCIKM_01304 9.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MIIMCIKM_01305 1.4e-105 ytaF P Probably functions as a manganese efflux pump
MIIMCIKM_01306 5.4e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MIIMCIKM_01307 6.8e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MIIMCIKM_01308 1.4e-68 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MIIMCIKM_01309 3e-66
MIIMCIKM_01310 1.8e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MIIMCIKM_01311 7.9e-250 dnaB L Membrane attachment protein
MIIMCIKM_01312 1.7e-173 dnaI L Primosomal protein DnaI
MIIMCIKM_01313 4.2e-225 mqnC 1.21.98.1, 2.5.1.120, 2.5.1.77 H Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)
MIIMCIKM_01314 6.2e-162 ytxC S YtxC-like family
MIIMCIKM_01315 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIIMCIKM_01316 5e-187 S Oxidoreductase family, NAD-binding Rossmann fold
MIIMCIKM_01317 1e-178 strT C Aldo/keto reductase family
MIIMCIKM_01318 1.2e-274 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MIIMCIKM_01319 8.6e-123
MIIMCIKM_01320 4.9e-238 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIIMCIKM_01321 1.2e-118 macB V ABC transporter, ATP-binding protein
MIIMCIKM_01322 2.3e-210 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MIIMCIKM_01323 4.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIIMCIKM_01324 4.4e-29 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MIIMCIKM_01325 2.3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MIIMCIKM_01326 3.8e-41 yktA S Belongs to the UPF0223 family
MIIMCIKM_01327 5.4e-118 yktB S Belongs to the UPF0637 family
MIIMCIKM_01328 3.5e-154 suhB 3.1.3.25 G Inositol monophosphatase
MIIMCIKM_01329 1.1e-164 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MIIMCIKM_01330 3.4e-11 S Family of unknown function (DUF5325)
MIIMCIKM_01331 0.0 typA T GTP-binding protein TypA
MIIMCIKM_01332 7.2e-53 ylaH S YlaH-like protein
MIIMCIKM_01333 3.2e-32 ylaI S protein conserved in bacteria
MIIMCIKM_01334 2.7e-252 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MIIMCIKM_01335 5.7e-94 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MIIMCIKM_01336 9e-41 ylaN S Belongs to the UPF0358 family
MIIMCIKM_01337 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MIIMCIKM_01338 4.1e-159 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MIIMCIKM_01339 1.1e-200 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MIIMCIKM_01340 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIIMCIKM_01341 9.7e-104 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MIIMCIKM_01342 1.1e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MIIMCIKM_01343 3.9e-93 yozB S membrane
MIIMCIKM_01344 4.6e-85
MIIMCIKM_01345 9.5e-64 ylbA S YugN-like family
MIIMCIKM_01346 9.5e-214 ylbC S protein with SCP PR1 domains
MIIMCIKM_01347 4.6e-85 yiiD Q protein, possibly involved in aromatic compounds catabolism
MIIMCIKM_01348 3.5e-73 ylbD S Putative coat protein
MIIMCIKM_01349 1.2e-31 ylbE S YlbE-like protein
MIIMCIKM_01350 1.3e-142 rimK1 HJ Prokaryotic glutathione synthetase, ATP-grasp domain
MIIMCIKM_01351 7.9e-60 ylbF S Belongs to the UPF0342 family
MIIMCIKM_01352 1.1e-46 ylbG S UPF0298 protein
MIIMCIKM_01353 4.1e-65 S Methylthioribose kinase
MIIMCIKM_01354 3.7e-99 rsmD 2.1.1.171 L Methyltransferase
MIIMCIKM_01355 7.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MIIMCIKM_01356 8.5e-221 ylbJ S Sporulation integral membrane protein YlbJ
MIIMCIKM_01357 4e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
MIIMCIKM_01358 3.4e-194 ylbL T Belongs to the peptidase S16 family
MIIMCIKM_01359 1.4e-231 ylbM S Belongs to the UPF0348 family
MIIMCIKM_01360 4.4e-94 yceD S metal-binding, possibly nucleic acid-binding protein
MIIMCIKM_01361 1.3e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MIIMCIKM_01362 6.4e-67 S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MIIMCIKM_01363 3.6e-93 ylbP K n-acetyltransferase
MIIMCIKM_01364 1.7e-162 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIIMCIKM_01365 6.5e-10 S Protein of unknown function (DUF3397)
MIIMCIKM_01366 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MIIMCIKM_01367 2.6e-79 mraZ K Belongs to the MraZ family
MIIMCIKM_01368 2.1e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MIIMCIKM_01369 2.3e-54 ftsL D cell division protein FtsL
MIIMCIKM_01370 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MIIMCIKM_01371 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MIIMCIKM_01372 1e-273 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIIMCIKM_01373 2.6e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MIIMCIKM_01374 2.5e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIIMCIKM_01375 1.1e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIIMCIKM_01376 2.3e-185 spoVE D Belongs to the SEDS family
MIIMCIKM_01377 8.5e-126 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MIIMCIKM_01379 1.3e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MIIMCIKM_01380 1.1e-185 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MIIMCIKM_01381 6.6e-162 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MIIMCIKM_01382 1.1e-124 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIIMCIKM_01383 2.1e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIIMCIKM_01384 9.8e-46 ylmC S sporulation protein
MIIMCIKM_01385 7.7e-149 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MIIMCIKM_01386 2e-118 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIIMCIKM_01387 3.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MIIMCIKM_01388 2e-43 yggT S membrane
MIIMCIKM_01389 3e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MIIMCIKM_01390 4.8e-64 divIVA D Cell division initiation protein
MIIMCIKM_01391 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIIMCIKM_01392 5.5e-115 dksA T COG1734 DnaK suppressor protein
MIIMCIKM_01393 1.8e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MIIMCIKM_01394 8.8e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MIIMCIKM_01395 3.2e-104 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MIIMCIKM_01396 1.5e-231 pyrP F Xanthine uracil
MIIMCIKM_01397 1.1e-164 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MIIMCIKM_01398 2.3e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MIIMCIKM_01399 3.8e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MIIMCIKM_01400 0.0 carB 6.3.5.5 F Belongs to the CarB family
MIIMCIKM_01401 1.5e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MIIMCIKM_01402 7.4e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MIIMCIKM_01403 1e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MIIMCIKM_01404 2.2e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIIMCIKM_01405 7.2e-121 Q ubiE/COQ5 methyltransferase family
MIIMCIKM_01407 0.0 yfhO S Bacterial membrane protein YfhO
MIIMCIKM_01408 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MIIMCIKM_01409 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MIIMCIKM_01410 3.5e-39 ylzA S Belongs to the UPF0296 family
MIIMCIKM_01411 3.7e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MIIMCIKM_01412 9.2e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MIIMCIKM_01413 1.9e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIIMCIKM_01414 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIIMCIKM_01415 9.9e-169 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIIMCIKM_01416 2.2e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MIIMCIKM_01417 9.1e-131 stp 3.1.3.16 T phosphatase
MIIMCIKM_01418 0.0 KLT serine threonine protein kinase
MIIMCIKM_01419 7.4e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MIIMCIKM_01420 2.7e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MIIMCIKM_01422 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MIIMCIKM_01423 2.5e-59 asp S protein conserved in bacteria
MIIMCIKM_01424 2.8e-307 yloV S kinase related to dihydroxyacetone kinase
MIIMCIKM_01425 8.5e-151 degV3 S protein conserved in bacteria
MIIMCIKM_01426 3.2e-121 sdaAB 4.3.1.17 E L-serine dehydratase
MIIMCIKM_01427 7.7e-147 sdaAA 4.3.1.17 E L-serine dehydratase
MIIMCIKM_01428 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MIIMCIKM_01429 1.3e-97 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MIIMCIKM_01430 1.1e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MIIMCIKM_01431 4.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MIIMCIKM_01432 2.3e-128 IQ reductase
MIIMCIKM_01433 5.4e-31 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MIIMCIKM_01434 4.4e-138 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MIIMCIKM_01435 3.2e-09 yfkK S Belongs to the UPF0435 family
MIIMCIKM_01436 0.0 smc D Required for chromosome condensation and partitioning
MIIMCIKM_01437 2.6e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MIIMCIKM_01438 2.3e-51 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MIIMCIKM_01439 1.1e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIIMCIKM_01440 6.4e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MIIMCIKM_01441 2.5e-33 ylqC S Belongs to the UPF0109 family
MIIMCIKM_01442 9e-69 ylqD S YlqD protein
MIIMCIKM_01443 4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIIMCIKM_01444 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MIIMCIKM_01445 0.0 argS 6.1.1.19 J Arginyl tRNA synthetase N terminal dom
MIIMCIKM_01447 5e-27 celF 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MIIMCIKM_01448 4.3e-08 ywbA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIIMCIKM_01449 5.1e-30 cspL K Cold shock
MIIMCIKM_01450 1.1e-192 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MIIMCIKM_01451 5.6e-257 adcA P Zinc-uptake complex component A periplasmic
MIIMCIKM_01452 2.1e-134 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MIIMCIKM_01453 8.5e-132 adcB P ABC 3 transport family
MIIMCIKM_01454 4e-265 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIIMCIKM_01455 5.3e-167 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
MIIMCIKM_01456 8.9e-164 MA20_14845 4.2.1.141 S Fumarylacetoacetate (FAA) hydrolase family
MIIMCIKM_01457 3e-139 K helix_turn_helix isocitrate lyase regulation
MIIMCIKM_01458 0.0 yjhG 4.2.1.82 EG Dehydratase family
MIIMCIKM_01459 2.1e-242 yjhF EG COG2610 H gluconate symporter and related permeases
MIIMCIKM_01460 5.9e-32 K MerR family transcriptional regulator
MIIMCIKM_01461 7.9e-140 IQ Enoyl-(Acyl carrier protein) reductase
MIIMCIKM_01462 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIIMCIKM_01463 1.7e-209 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
MIIMCIKM_01464 4.4e-43 ulaB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
MIIMCIKM_01465 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
MIIMCIKM_01466 1.5e-40
MIIMCIKM_01467 3.6e-52
MIIMCIKM_01468 5.2e-267 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIIMCIKM_01469 3.2e-80 fld C Flavodoxin
MIIMCIKM_01470 7.1e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MIIMCIKM_01471 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIIMCIKM_01472 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MIIMCIKM_01473 1.8e-44 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIIMCIKM_01474 5.6e-91 yizA S DinB family
MIIMCIKM_01475 9.9e-180
MIIMCIKM_01477 1.4e-157 yufQ S Belongs to the binding-protein-dependent transport system permease family
MIIMCIKM_01478 1.5e-189 yufP S Belongs to the binding-protein-dependent transport system permease family
MIIMCIKM_01479 3.4e-283 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MIIMCIKM_01480 5e-204 bmpA S ABC-type transport system, periplasmic component surface lipoprotein
MIIMCIKM_01481 1.5e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
MIIMCIKM_01482 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIIMCIKM_01483 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MIIMCIKM_01484 8.3e-131 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MIIMCIKM_01485 6.7e-153 fhuC 3.6.3.34 HP ABC transporter
MIIMCIKM_01486 3.8e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIIMCIKM_01487 5.9e-178 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIIMCIKM_01489 2.3e-26 mepA V MATE efflux family protein
MIIMCIKM_01490 7.6e-171 lacX G Aldose 1-epimerase
MIIMCIKM_01491 0.0 acyII 3.5.1.11, 3.5.1.97 S Penicillin amidase
MIIMCIKM_01492 5.8e-183 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MIIMCIKM_01493 4e-81 glnQ2 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIIMCIKM_01494 2.6e-88
MIIMCIKM_01496 2e-86 4.1.2.14 S KDGP aldolase
MIIMCIKM_01497 5.8e-82 L Transposase IS200 like
MIIMCIKM_01498 3.1e-18
MIIMCIKM_01500 8.4e-75 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MIIMCIKM_01501 4.6e-210 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MIIMCIKM_01502 2.4e-54 yhaH D gas vesicle protein
MIIMCIKM_01503 1.2e-108 hpr K Negative regulator of protease production and sporulation
MIIMCIKM_01504 1.7e-108 S Protein conserved in bacteria
MIIMCIKM_01506 1.4e-160 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MIIMCIKM_01507 6.2e-45 yhaL S Sporulation protein YhaL
MIIMCIKM_01508 8e-182 yhaM L Shows a 3'-5' exoribonuclease activity
MIIMCIKM_01509 3.3e-261 T PhoQ Sensor
MIIMCIKM_01510 1.3e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_01511 4.2e-42
MIIMCIKM_01513 1.4e-158 yhaX S hydrolases of the HAD superfamily
MIIMCIKM_01514 1.4e-54 yheA S Belongs to the UPF0342 family
MIIMCIKM_01515 7e-209 yheB S Belongs to the UPF0754 family
MIIMCIKM_01516 4.2e-17 yheE S Family of unknown function (DUF5342)
MIIMCIKM_01517 4.1e-22
MIIMCIKM_01518 1.7e-162 lrp QT PucR C-terminal helix-turn-helix domain
MIIMCIKM_01519 2.6e-205 msmK P Belongs to the ABC transporter superfamily
MIIMCIKM_01520 1.8e-78 K Sigma-70, region 4
MIIMCIKM_01521 4.3e-217
MIIMCIKM_01523 3.6e-285 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MIIMCIKM_01524 1.2e-135 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MIIMCIKM_01525 1.9e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MIIMCIKM_01526 2.8e-257 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MIIMCIKM_01527 8.5e-218 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MIIMCIKM_01528 7.2e-95 lemA S LemA family
MIIMCIKM_01529 9.6e-150 htpX O Peptidase family M48
MIIMCIKM_01530 9.6e-233 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIIMCIKM_01531 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIIMCIKM_01532 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIIMCIKM_01533 4.4e-274 ycgB S Stage V sporulation protein R
MIIMCIKM_01534 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MIIMCIKM_01535 4.3e-305 glpD 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
MIIMCIKM_01536 2.5e-124 sfsA S Sugar fermentation stimulation protein
MIIMCIKM_01537 5.4e-305 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MIIMCIKM_01539 1.4e-71
MIIMCIKM_01540 1.1e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MIIMCIKM_01541 2.4e-118 ycgM Q Fumarylacetoacetate (FAA) hydrolase family
MIIMCIKM_01542 2.2e-226 mtnE 2.6.1.83 E Aminotransferase
MIIMCIKM_01543 1e-131 frp 1.5.1.39 C Oxidoreductase
MIIMCIKM_01544 1.8e-136 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MIIMCIKM_01545 2.2e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MIIMCIKM_01546 3.3e-132 yvoA K transcriptional
MIIMCIKM_01547 1.1e-275 4.3.2.1 E argininosuccinate lyase
MIIMCIKM_01548 2.1e-126 K UTRA
MIIMCIKM_01551 1.7e-07
MIIMCIKM_01556 3.6e-58 ygzB S UPF0295 protein
MIIMCIKM_01557 1.5e-79 perR P Belongs to the Fur family
MIIMCIKM_01558 2.7e-48 S Cyclic-di-AMP receptor
MIIMCIKM_01559 3.4e-180 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIIMCIKM_01560 1.6e-87 bcp 1.11.1.15 O Peroxiredoxin
MIIMCIKM_01561 1.9e-247 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MIIMCIKM_01562 3.8e-185 ygaE S Membrane
MIIMCIKM_01563 0.0 ygaD V ABC transporter
MIIMCIKM_01564 1.5e-102 ygaC J Belongs to the UPF0374 family
MIIMCIKM_01565 5.4e-16 S Small, acid-soluble spore protein, gamma-type
MIIMCIKM_01566 1.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_01567 6.9e-19 yfhS
MIIMCIKM_01568 4.1e-59
MIIMCIKM_01569 1.2e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_01570 3e-209 mutY L A G-specific
MIIMCIKM_01571 2.8e-190 yfhP S membrane-bound metal-dependent
MIIMCIKM_01573 1.2e-21 S YpzG-like protein
MIIMCIKM_01574 1.4e-53 yfhH S Protein of unknown function (DUF1811)
MIIMCIKM_01575 3.9e-145 recX 2.4.1.337 GT4 S Modulates RecA activity
MIIMCIKM_01576 2.5e-169 yfhF S nucleoside-diphosphate sugar epimerase
MIIMCIKM_01577 5.5e-49
MIIMCIKM_01578 1.3e-206 mccF 3.4.17.13 V LD-carboxypeptidase
MIIMCIKM_01579 7.2e-272 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIIMCIKM_01580 1.6e-61
MIIMCIKM_01582 1.5e-71 ywgB K Transcriptional regulator
MIIMCIKM_01583 1.1e-172 ahpF 1.8.1.9 O Pyridine nucleotide-disulphide oxidoreductase
MIIMCIKM_01584 2.9e-150 pdaA G deacetylase
MIIMCIKM_01585 1.9e-144 S Domain of unknown function (DUF368)
MIIMCIKM_01586 2.5e-245 yhdP S COG1253 Hemolysins and related proteins containing CBS domains
MIIMCIKM_01587 3.8e-119 gpmB 5.4.2.11 G Belongs to the phosphoglycerate mutase family
MIIMCIKM_01588 3.8e-220 yfkA S YfkB-like domain
MIIMCIKM_01589 1.8e-147 yfkD S YfkD-like protein
MIIMCIKM_01592 2.2e-21 S Fur-regulated basic protein B
MIIMCIKM_01593 5.8e-247 cydA 1.10.3.14 C oxidase, subunit
MIIMCIKM_01594 2.5e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MIIMCIKM_01595 5.9e-146
MIIMCIKM_01596 0.0 pepF2 E COG1164 Oligoendopeptidase F
MIIMCIKM_01597 4.3e-296 katB 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MIIMCIKM_01598 3.8e-251 iucD_1 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
MIIMCIKM_01599 1.5e-258 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MIIMCIKM_01600 3.2e-112 rnhA 3.1.26.4 L Caulimovirus viroplasmin
MIIMCIKM_01601 1.4e-40
MIIMCIKM_01602 2e-46 abrB K SpoVT / AbrB like domain
MIIMCIKM_01603 1e-56
MIIMCIKM_01604 2.9e-238 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MIIMCIKM_01605 2.2e-182 mreB D Rod-share determining protein MreBH
MIIMCIKM_01606 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MIIMCIKM_01607 1.1e-164 fruB 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MIIMCIKM_01608 7.2e-77 fruR K Transcriptional regulator
MIIMCIKM_01609 6.6e-82
MIIMCIKM_01610 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MIIMCIKM_01611 2.2e-139 K helix_turn_helix, mercury resistance
MIIMCIKM_01612 1.6e-160 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01613 1.6e-171 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01614 3e-264 G Bacterial extracellular solute-binding protein
MIIMCIKM_01615 2.2e-139 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MIIMCIKM_01616 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MIIMCIKM_01617 3e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MIIMCIKM_01618 4.8e-137 ycsF S Belongs to the UPF0271 (lamB) family
MIIMCIKM_01619 1.7e-60 K helix_turn_helix, mercury resistance
MIIMCIKM_01620 1.9e-115 drgA C nitroreductase
MIIMCIKM_01621 9e-184 scrR K helix_turn _helix lactose operon repressor
MIIMCIKM_01622 9.8e-304 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
MIIMCIKM_01623 1.4e-256 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIIMCIKM_01624 7.7e-182 K Transcriptional regulator
MIIMCIKM_01625 3.9e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MIIMCIKM_01626 1.1e-242 G Tripartite ATP-independent periplasmic transporter, DctM component
MIIMCIKM_01627 8.3e-32
MIIMCIKM_01628 1.7e-116 H Methyltransferase
MIIMCIKM_01629 2.2e-154 K Helix-turn-helix domain, rpiR family
MIIMCIKM_01630 1.1e-153 fldX 1.1.1.31 I Domain of unknown function (DUF1932)
MIIMCIKM_01631 0.0 uidA G Belongs to the glycosyl hydrolase 2 family
MIIMCIKM_01632 1.2e-82 6.3.3.2 S ASCH
MIIMCIKM_01633 7.7e-82 nsrR K Transcriptional regulator
MIIMCIKM_01634 2e-70 hit FG Scavenger mRNA decapping enzyme C-term binding
MIIMCIKM_01635 5.5e-186 cbrA5 P Ferrichrome ABC transporter substrate-binding protein
MIIMCIKM_01636 0.0 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIIMCIKM_01637 4.3e-138 P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MIIMCIKM_01638 2.7e-144 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01639 3.3e-189 P NMT1-like family
MIIMCIKM_01640 8.2e-140 P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MIIMCIKM_01641 6.4e-146 MA20_40340 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01642 9.3e-186 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MIIMCIKM_01643 2.8e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MIIMCIKM_01644 1.7e-105 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MIIMCIKM_01645 1.4e-164 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MIIMCIKM_01646 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MIIMCIKM_01647 3.7e-91 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MIIMCIKM_01648 2.3e-242 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MIIMCIKM_01649 1.8e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MIIMCIKM_01650 6.6e-309 pucR QT COG2508 Regulator of polyketide synthase expression
MIIMCIKM_01651 1e-90 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 S OHCU decarboxylase
MIIMCIKM_01652 8.7e-47 S Sporulation protein YpjB (SpoYpjB)
MIIMCIKM_01653 5.9e-118 yugP S Zn-dependent protease
MIIMCIKM_01654 1.7e-213 tcaB EGP Major facilitator Superfamily
MIIMCIKM_01655 9.6e-158 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MIIMCIKM_01656 2.4e-59 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MIIMCIKM_01657 2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MIIMCIKM_01658 5e-75 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MIIMCIKM_01659 4.6e-88 M Acetyltransferase (GNAT) domain
MIIMCIKM_01660 4.8e-240 rtcB 6.5.1.3 S tRNA-splicing ligase RtcB
MIIMCIKM_01661 1.4e-37
MIIMCIKM_01662 3.5e-76 yjcF S Acetyltransferase (GNAT) domain
MIIMCIKM_01663 2.6e-143 Q Methyltransferase domain
MIIMCIKM_01664 1.2e-51
MIIMCIKM_01666 1.2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MIIMCIKM_01667 1.7e-96 S Protein of unknown function (DUF1706)
MIIMCIKM_01668 1.5e-269 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MIIMCIKM_01669 2.3e-133 yodH Q Methyltransferase
MIIMCIKM_01670 6.8e-137 M 3D domain
MIIMCIKM_01671 6.8e-174 M 3D domain
MIIMCIKM_01672 1.9e-158 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIIMCIKM_01673 5.3e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MIIMCIKM_01674 2.5e-152 ysaA S HAD-hyrolase-like
MIIMCIKM_01675 1.8e-102 ykoE S ABC-type cobalt transport system, permease component
MIIMCIKM_01676 1.5e-272 ykoD 3.6.3.24 P ABC transporter
MIIMCIKM_01677 2.1e-143 ykoC P Cobalt transport protein
MIIMCIKM_01678 1.3e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MIIMCIKM_01679 4e-107 yvdD_1 3.2.2.10 S Belongs to the LOG family
MIIMCIKM_01680 1.3e-88 lytE2 M COG1388 FOG LysM repeat
MIIMCIKM_01681 5.4e-236 els S Acetyltransferase
MIIMCIKM_01682 3.1e-104 yvdT K Transcriptional regulator
MIIMCIKM_01683 2.5e-186 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIIMCIKM_01684 4.7e-137 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MIIMCIKM_01685 2.5e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIIMCIKM_01686 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MIIMCIKM_01687 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
MIIMCIKM_01688 5.8e-58 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MIIMCIKM_01689 0.0 iucA 6.3.2.38 Q Siderophore biosynthesis protein
MIIMCIKM_01690 0.0 asbB Q IucA / IucC family
MIIMCIKM_01691 5.6e-236 asbC 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MIIMCIKM_01692 1.7e-41 asbD IQ Phosphopantetheine attachment site
MIIMCIKM_01693 1.2e-190 asbE IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MIIMCIKM_01694 2.7e-162 asbF 4.2.1.118 G Xylose isomerase-like TIM barrel
MIIMCIKM_01695 2.2e-99 gmhB 3.1.3.82, 3.1.3.83 E D,D-heptose 1,7-bisphosphate phosphatase
MIIMCIKM_01696 6.1e-249 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MIIMCIKM_01697 1.2e-154 xth 3.1.11.2 L exodeoxyribonuclease III
MIIMCIKM_01698 7.9e-126 yeeN K transcriptional regulatory protein
MIIMCIKM_01699 9.3e-189 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MIIMCIKM_01700 4e-142 S Integral membrane protein DUF92
MIIMCIKM_01701 7.7e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MIIMCIKM_01702 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MIIMCIKM_01703 2e-126 G PFAM Glycoside hydrolase 15-related
MIIMCIKM_01704 3.7e-61
MIIMCIKM_01705 9.1e-78 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIIMCIKM_01706 0.0 mrdA 3.4.16.4 M penicillin-binding protein
MIIMCIKM_01707 3.2e-234 yqgE EGP Major facilitator superfamily
MIIMCIKM_01708 1.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MIIMCIKM_01709 8.4e-09
MIIMCIKM_01714 2.1e-275 nptA P COG1283 Na phosphate symporter
MIIMCIKM_01715 5.6e-197 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIIMCIKM_01716 2.2e-117 O NfeD-like C-terminal, partner-binding
MIIMCIKM_01717 4.7e-152 ypuA S Secreted protein
MIIMCIKM_01718 1.7e-186 EGP Major facilitator Superfamily
MIIMCIKM_01719 3.4e-61 fimV NU translation initiation factor activity
MIIMCIKM_01720 1.2e-200 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MIIMCIKM_01721 6.4e-67 yqfX S membrane
MIIMCIKM_01722 2e-111 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MIIMCIKM_01723 7.4e-38 S Domain of Unknown Function (DUF1540)
MIIMCIKM_01724 1.4e-77 zur P Belongs to the Fur family
MIIMCIKM_01725 4e-140 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MIIMCIKM_01726 1.1e-144 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MIIMCIKM_01727 2.2e-131 GH23 M Transglycosylase SLT domain
MIIMCIKM_01728 2.5e-214 pilS 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MIIMCIKM_01729 1.1e-08 yqfT S Protein of unknown function (DUF2624)
MIIMCIKM_01730 8.1e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MIIMCIKM_01731 8e-252 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MIIMCIKM_01732 4.2e-49 yqfQ S YqfQ-like protein
MIIMCIKM_01733 1.4e-84 carD K Transcription factor
MIIMCIKM_01734 1.4e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MIIMCIKM_01735 1.9e-195 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MIIMCIKM_01736 6.2e-140 trmK 2.1.1.217 S SAM-dependent methyltransferase
MIIMCIKM_01737 6e-64 C COG2010 Cytochrome c, mono- and diheme variants
MIIMCIKM_01738 1.9e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MIIMCIKM_01739 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MIIMCIKM_01740 9.5e-80 yaiI S Belongs to the UPF0178 family
MIIMCIKM_01741 1.6e-143 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MIIMCIKM_01742 2.6e-112 ccpN K CBS domain
MIIMCIKM_01743 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MIIMCIKM_01744 2.4e-172 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MIIMCIKM_01746 1.3e-142 recO L Involved in DNA repair and RecF pathway recombination
MIIMCIKM_01747 1.6e-17 S YqzL-like protein
MIIMCIKM_01748 1.6e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MIIMCIKM_01749 1e-72 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MIIMCIKM_01750 1.3e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MIIMCIKM_01751 5.1e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MIIMCIKM_01752 3.1e-150 yqfF S membrane-associated HD superfamily hydrolase
MIIMCIKM_01753 9.7e-73 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MIIMCIKM_01754 3.3e-28 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MIIMCIKM_01757 6e-15 S Phage-like element PBSX protein XtrA
MIIMCIKM_01758 8.6e-41 K BRO family, N-terminal domain
MIIMCIKM_01759 7.1e-115 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
MIIMCIKM_01760 1.9e-39 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MIIMCIKM_01763 5.8e-55 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MIIMCIKM_01767 7.3e-41 xkdB K sequence-specific DNA binding
MIIMCIKM_01769 1.2e-31
MIIMCIKM_01773 7.1e-62
MIIMCIKM_01774 1.7e-33 K sequence-specific DNA binding
MIIMCIKM_01775 1.5e-11
MIIMCIKM_01776 4.7e-53 KLT serine threonine protein kinase
MIIMCIKM_01777 3e-42 E IrrE N-terminal-like domain
MIIMCIKM_01778 3.1e-25
MIIMCIKM_01779 1.5e-107 S recombinase activity
MIIMCIKM_01781 1.1e-168 S membrane
MIIMCIKM_01782 2.4e-242 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MIIMCIKM_01784 3.5e-70 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MIIMCIKM_01785 1.8e-115 mucD 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIIMCIKM_01786 2e-61 yojF S Protein of unknown function (DUF1806)
MIIMCIKM_01787 8.2e-125 bshB2 S deacetylase
MIIMCIKM_01788 2.5e-169 polA 2.7.7.7 L Helix-hairpin-helix class 2 (Pol1 family) motifs
MIIMCIKM_01789 5.8e-105 speG J Acetyltransferase (GNAT) domain
MIIMCIKM_01790 1.6e-90 yocC
MIIMCIKM_01791 6.4e-58 ytxJ O Protein of unknown function (DUF2847)
MIIMCIKM_01792 0.0 recQ 3.6.4.12 L DNA helicase
MIIMCIKM_01793 6.3e-159 S reductase
MIIMCIKM_01794 4e-303 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MIIMCIKM_01795 5.4e-32 yozC
MIIMCIKM_01796 5.2e-189 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MIIMCIKM_01797 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MIIMCIKM_01799 2.5e-208 2.1.1.163, 2.1.1.201 Q O-methyltransferase
MIIMCIKM_01800 6.3e-119 M lytic transglycosylase activity
MIIMCIKM_01802 3.6e-76 osmC O redox protein, regulator of disulfide bond formation
MIIMCIKM_01803 0.0 topB1 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIIMCIKM_01805 2.3e-173 V COG1131 ABC-type multidrug transport system, ATPase component
MIIMCIKM_01806 1.6e-126 V ABC-2 type transporter
MIIMCIKM_01807 1.6e-120 S ABC-2 type transporter
MIIMCIKM_01808 7.3e-203 selA 2.9.1.1, 4.3.1.29 E L-seryl-tRNA selenium transferase
MIIMCIKM_01809 2.5e-113 S Domain of unknown function (DUF4310)
MIIMCIKM_01810 6.2e-140 S Domain of unknown function (DUF4311)
MIIMCIKM_01811 3.5e-58 S Domain of unknown function (DUF4312)
MIIMCIKM_01812 7.7e-61 S Glycine-rich SFCGS
MIIMCIKM_01813 4.9e-51 S PRD domain
MIIMCIKM_01814 2.9e-218 dho 3.5.2.3 S amidohydrolase
MIIMCIKM_01815 0.0 K Mga helix-turn-helix domain
MIIMCIKM_01816 0.0 pbg 3.2.1.23 G beta-galactosidase
MIIMCIKM_01817 1e-164 K AraC-like ligand binding domain
MIIMCIKM_01818 7.3e-132 L AAA domain
MIIMCIKM_01820 4.5e-108 S Domain of unknown function (DUF4297)
MIIMCIKM_01821 7.1e-203 S homoserine kinase type II (protein kinase fold)
MIIMCIKM_01822 2.4e-32 yjcS S Antibiotic biosynthesis monooxygenase
MIIMCIKM_01823 1.3e-44 ykvN K HxlR-like helix-turn-helix
MIIMCIKM_01824 3.1e-275 pbpE V Beta-lactamase
MIIMCIKM_01825 1.7e-140 K helix_turn_helix, mercury resistance
MIIMCIKM_01826 2.2e-93 2.7.1.48, 3.1.3.18 F uridine kinase
MIIMCIKM_01827 1.5e-66
MIIMCIKM_01828 6.6e-257 ypfE EGP Fungal trichothecene efflux pump (TRI12)
MIIMCIKM_01829 4.2e-77 nsrR3 K Transcriptional regulator
MIIMCIKM_01830 1.6e-106 K Bacterial transcriptional repressor C-terminal
MIIMCIKM_01831 8.5e-251 npr 1.11.1.1 P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MIIMCIKM_01832 2.6e-10 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MIIMCIKM_01833 1.4e-228 eph 3.3.2.9 S Epoxide hydrolase N terminus
MIIMCIKM_01834 2.7e-171 S thiolester hydrolase activity
MIIMCIKM_01835 3.2e-83 yvmB1 K helix_turn_helix multiple antibiotic resistance protein
MIIMCIKM_01836 5.2e-66 J oxidation-reduction process
MIIMCIKM_01837 1.1e-281 yhjG CH FAD binding domain
MIIMCIKM_01838 3.9e-202 ybcL EGP Major facilitator Superfamily
MIIMCIKM_01839 1.1e-49 ybzH K Helix-turn-helix domain
MIIMCIKM_01840 3e-48 yxcB K Transcriptional regulator C-terminal region
MIIMCIKM_01841 1.1e-36 S Protein of unknown function (DUF3021)
MIIMCIKM_01843 0.0 yobO M Pectate lyase superfamily protein
MIIMCIKM_01851 1.5e-07
MIIMCIKM_01860 7.3e-172 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
MIIMCIKM_01861 3.3e-141 rpl K Helix-turn-helix domain, rpiR family
MIIMCIKM_01862 1.3e-165 T Belongs to the universal stress protein A family
MIIMCIKM_01864 1.6e-51
MIIMCIKM_01865 2.4e-56
MIIMCIKM_01866 7.3e-197 potD2 E COG0687 Spermidine putrescine-binding periplasmic protein
MIIMCIKM_01867 4.1e-175 iunH3 3.2.2.1 F nucleoside hydrolase
MIIMCIKM_01868 2.1e-138 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
MIIMCIKM_01869 7.4e-133 potC3 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01870 1.3e-196 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MIIMCIKM_01871 0.0 ade 3.5.4.2 F Adenine deaminase C-terminal domain
MIIMCIKM_01872 1.9e-308 M1-554 G Endonuclease Exonuclease Phosphatase
MIIMCIKM_01873 4.1e-13 S Inner spore coat protein D
MIIMCIKM_01874 3.3e-61 Z012_01525 FJ tRNA wobble adenosine to inosine editing
MIIMCIKM_01875 1.4e-156 P PFAM binding-protein-dependent transport systems inner membrane component
MIIMCIKM_01876 1.1e-161 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01877 3.1e-242 G ABC transporter substrate-binding protein
MIIMCIKM_01878 5.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MIIMCIKM_01879 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MIIMCIKM_01880 6.8e-136 lacR K DeoR C terminal sensor domain
MIIMCIKM_01881 9.4e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MIIMCIKM_01882 8e-293 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MIIMCIKM_01883 8.4e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MIIMCIKM_01884 4.4e-275 mdr EGP Major facilitator Superfamily
MIIMCIKM_01885 0.0 rocB E arginine degradation protein
MIIMCIKM_01886 9.4e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MIIMCIKM_01887 2.5e-49
MIIMCIKM_01888 7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_01889 1.5e-194 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MIIMCIKM_01890 3.9e-142 yvcR V ABC transporter, ATP-binding protein
MIIMCIKM_01891 0.0 V ABC transporter (permease)
MIIMCIKM_01893 0.0 copA 3.6.3.54 P P-type ATPase
MIIMCIKM_01894 4.7e-160 S CAAX amino terminal protease family protein
MIIMCIKM_01895 5.6e-172 K Putative sugar-binding domain
MIIMCIKM_01896 4.9e-60 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MIIMCIKM_01897 1.7e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MIIMCIKM_01898 1.2e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MIIMCIKM_01899 0.0
MIIMCIKM_01900 0.0 cca 2.7.7.19, 2.7.7.72, 3.1.13.3, 3.1.3.7 J Poly A polymerase head domain
MIIMCIKM_01902 9.2e-104 3.5.1.28 M Cell Wall Hydrolase
MIIMCIKM_01903 2.3e-107 J protein with SCP PR1 domains
MIIMCIKM_01904 3.7e-179 coaA 2.7.1.33 F Pantothenic acid kinase
MIIMCIKM_01905 8.1e-137 ywaC 2.7.6.5 S protein conserved in bacteria
MIIMCIKM_01906 4.9e-156 yjaZ O Zn-dependent protease
MIIMCIKM_01907 1.3e-142 yjbA S Belongs to the UPF0736 family
MIIMCIKM_01908 2.7e-10
MIIMCIKM_01909 1.5e-183 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MIIMCIKM_01911 3.3e-106 stoA CO Redoxin
MIIMCIKM_01912 2.1e-99 yueE S phosphohydrolase
MIIMCIKM_01913 3.5e-112 yplQ S protein, Hemolysin III
MIIMCIKM_01914 2.9e-13 yoeD G Helix-turn-helix domain
MIIMCIKM_01915 2.9e-237 S Putative glycosyl hydrolase domain
MIIMCIKM_01916 9.1e-98 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIIMCIKM_01918 1.3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MIIMCIKM_01919 2.1e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MIIMCIKM_01920 1.7e-237 yjbF S Competence protein
MIIMCIKM_01922 1.9e-172 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MIIMCIKM_01923 5.6e-73 yjbI S COG2346 Truncated hemoglobins
MIIMCIKM_01924 1.3e-96 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MIIMCIKM_01925 4.2e-98 yjbK S protein conserved in bacteria
MIIMCIKM_01926 5.5e-62 yjbL S Belongs to the UPF0738 family
MIIMCIKM_01927 2e-109 yjbM 2.7.6.5 S GTP pyrophosphokinase
MIIMCIKM_01928 6.8e-150 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIIMCIKM_01929 9.2e-172 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MIIMCIKM_01930 2e-138 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MIIMCIKM_01931 1.3e-60 yngL S Protein of unknown function (DUF1360)
MIIMCIKM_01932 3e-144 Q ubiE/COQ5 methyltransferase family
MIIMCIKM_01933 7.1e-127
MIIMCIKM_01934 3.4e-137
MIIMCIKM_01937 2.1e-68 cotX S Spore Coat Protein X and V domain
MIIMCIKM_01938 7e-72
MIIMCIKM_01939 0.0 yjcD 3.6.4.12 L DNA helicase
MIIMCIKM_01940 3e-187 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MIIMCIKM_01941 5.6e-189 comGB NU COG1459 Type II secretory pathway, component PulF
MIIMCIKM_01943 6.7e-09
MIIMCIKM_01947 2.4e-12 S Domain of unknown function (DUF5082)
MIIMCIKM_01948 2.5e-08 S Family of unknown function (DUF5344)
MIIMCIKM_01949 2.3e-255 S LXG domain of WXG superfamily
MIIMCIKM_01950 1.3e-108
MIIMCIKM_01951 6.7e-97
MIIMCIKM_01952 1.1e-149
MIIMCIKM_01953 3.4e-283 E Sodium:solute symporter family
MIIMCIKM_01954 4.6e-23
MIIMCIKM_01955 4.5e-230 2.8.3.16, 2.8.3.20 C acyl-CoA transferases carnitine dehydratase
MIIMCIKM_01956 2.7e-117 K FCD domain
MIIMCIKM_01957 8.3e-165 4.1.3.4, 4.1.3.46 E Hydroxymethylglutaryl-CoA lyase
MIIMCIKM_01958 1.3e-213 1.4.1.9 G Transmembrane secretion effector
MIIMCIKM_01960 3.2e-102 gntR K RpiR family transcriptional regulator
MIIMCIKM_01961 7.4e-181 EG COG2610 H gluconate symporter and related permeases
MIIMCIKM_01962 9.1e-127 garR 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MIIMCIKM_01963 1.1e-187 S Putative nucleotide-binding of sugar-metabolising enzyme
MIIMCIKM_01964 1.6e-224 abgB 3.5.1.47 S amidohydrolase
MIIMCIKM_01965 8e-157 metQ M Belongs to the nlpA lipoprotein family
MIIMCIKM_01966 3.3e-113 P COG2011 ABC-type metal ion transport system, permease component
MIIMCIKM_01967 3e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIIMCIKM_01968 1.9e-172 K helix_turn_helix, arabinose operon control protein
MIIMCIKM_01970 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MIIMCIKM_01971 0.0 aguA 3.2.1.139 G Belongs to the glycosyl hydrolase 67 family
MIIMCIKM_01972 3.9e-176 lplB G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_01973 1.7e-154 lplC G COG0395 ABC-type sugar transport system, permease component
MIIMCIKM_01974 0.0 G Bacterial extracellular solute-binding protein
MIIMCIKM_01975 2.4e-122 S Protein of unknown function, DUF624
MIIMCIKM_01976 6.8e-201 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
MIIMCIKM_01977 3e-15 D nuclear chromosome segregation
MIIMCIKM_01978 3.1e-220 hutI Q COG1228 Imidazolonepropionase and related amidohydrolases
MIIMCIKM_01979 1.2e-205 Q COG1228 Imidazolonepropionase and related amidohydrolases
MIIMCIKM_01980 1.9e-305 E COG0747 ABC-type dipeptide transport system, periplasmic component
MIIMCIKM_01981 9.9e-172 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_01982 3.5e-155 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_01983 7.6e-191 oppD P Belongs to the ABC transporter superfamily
MIIMCIKM_01984 3.7e-190 ddpF E Belongs to the ABC transporter superfamily
MIIMCIKM_01985 1e-176 S Protein of unknown function (DUF1177)
MIIMCIKM_01986 1.3e-243 3.5.1.18 E Acetylornithine deacetylase
MIIMCIKM_01987 3.6e-137 K Transcriptional regulator
MIIMCIKM_01988 1.6e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MIIMCIKM_01989 7.6e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G xylulose kinase
MIIMCIKM_01990 9.5e-205 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
MIIMCIKM_01991 1.1e-220 xylR GK ROK family
MIIMCIKM_01992 6.1e-125 MA20_14010 S Trehalose utilisation
MIIMCIKM_01993 1.1e-222 yrbE S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_01994 2.3e-284 KT PucR C-terminal helix-turn-helix domain
MIIMCIKM_01995 1.2e-109 hyuE 5.1.99.3 E Asp/Glu/Hydantoin racemase
MIIMCIKM_01996 2.6e-286 S OPT oligopeptide transporter protein
MIIMCIKM_01997 1.1e-187 S Protein of unknown function (DUF917)
MIIMCIKM_01998 2.1e-163 S Protein of unknown function (DUF1177)
MIIMCIKM_01999 7.5e-115 aroM E AroM protein
MIIMCIKM_02000 1.3e-176 E Thermophilic metalloprotease (M29)
MIIMCIKM_02001 9.6e-225 EGP Major facilitator Superfamily
MIIMCIKM_02002 3.1e-30 dmpI 5.3.2.6 S Tautomerase enzyme
MIIMCIKM_02003 7.3e-46 chrA P chromate transporter, chromate ion transporter
MIIMCIKM_02004 2.4e-156 chrA P chromate transporter, chromate ion transporter
MIIMCIKM_02006 1.8e-44 M1-594 S Thiamine-binding protein
MIIMCIKM_02007 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MIIMCIKM_02008 2.6e-242
MIIMCIKM_02010 6.6e-238 gntT EG gluconate transmembrane transporter activity
MIIMCIKM_02011 1.4e-167 2.7.1.196, 2.7.1.205 K sequence-specific DNA binding
MIIMCIKM_02012 4e-124 S protein conserved in bacteria
MIIMCIKM_02013 6e-54
MIIMCIKM_02015 3.9e-93 ssuE 1.5.1.38 S FMN reductase
MIIMCIKM_02016 1.5e-180 P ABC transporter substrate-binding protein
MIIMCIKM_02017 1.9e-211 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MIIMCIKM_02018 4.4e-135 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MIIMCIKM_02019 8.2e-134 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
MIIMCIKM_02020 2.1e-94 K Transcriptional regulator PadR-like family
MIIMCIKM_02021 1.4e-161 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
MIIMCIKM_02022 5.2e-123 K FCD
MIIMCIKM_02023 1.7e-223 S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_02024 3.9e-201 S oxidoreductase
MIIMCIKM_02025 6.2e-185 G Bacterial extracellular solute-binding protein, family 7
MIIMCIKM_02026 2.8e-77 G Tripartite ATP-independent periplasmic transporters, DctQ component
MIIMCIKM_02027 2.7e-212 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MIIMCIKM_02028 2.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MIIMCIKM_02029 1.9e-219 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MIIMCIKM_02030 7.1e-187 cysP P phosphate transporter
MIIMCIKM_02031 5.5e-112 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MIIMCIKM_02032 1.7e-276 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MIIMCIKM_02033 1.3e-142 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 C CbiX
MIIMCIKM_02034 8.3e-111 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MIIMCIKM_02035 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MIIMCIKM_02036 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MIIMCIKM_02037 7.4e-20
MIIMCIKM_02038 1e-159 V ABC transporter
MIIMCIKM_02039 1.8e-60 gntR1 K GntR family transcriptional regulator
MIIMCIKM_02040 1.7e-218 mii 5.3.3.6 S PrpF protein
MIIMCIKM_02041 6.1e-68 S Tripartite tricarboxylate transporter TctB family
MIIMCIKM_02042 1.4e-262 S Tripartite tricarboxylate transporter TctA family
MIIMCIKM_02043 3.9e-212 S Tripartite tricarboxylate transporter family receptor
MIIMCIKM_02044 1.3e-167 yraN K Transcriptional regulator
MIIMCIKM_02045 4.3e-200 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
MIIMCIKM_02046 3e-292 C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
MIIMCIKM_02047 3.6e-196 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MIIMCIKM_02048 1.1e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MIIMCIKM_02049 4.8e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIIMCIKM_02050 5.3e-104 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MIIMCIKM_02051 7e-104 tetR K Bacterial regulatory proteins, tetR family
MIIMCIKM_02052 3.8e-181 ybcL EGP Major facilitator Superfamily
MIIMCIKM_02053 8.1e-166 arsB P Arsenic resistance protein
MIIMCIKM_02054 6e-97
MIIMCIKM_02055 1.6e-131 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MIIMCIKM_02056 6.3e-45 2.7.1.196, 2.7.1.205 G phosphotransferase system
MIIMCIKM_02057 3.5e-52 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
MIIMCIKM_02058 1.8e-93 ywbA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIIMCIKM_02059 2.7e-32 ccmF O cytochrome C
MIIMCIKM_02060 2.9e-171 yoaV3 EG EamA-like transporter family
MIIMCIKM_02061 5.7e-206 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIIMCIKM_02062 1.4e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MIIMCIKM_02063 2.6e-101 D peptidase
MIIMCIKM_02064 2.7e-152 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MIIMCIKM_02065 1.4e-124 ftsE D cell division ATP-binding protein FtsE
MIIMCIKM_02066 2.5e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MIIMCIKM_02067 5.1e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIIMCIKM_02068 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MIIMCIKM_02069 7.1e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIIMCIKM_02070 2.9e-30 cspB K cold-shock protein
MIIMCIKM_02071 2.6e-152
MIIMCIKM_02073 1.3e-66 fliS N flagellar protein FliS
MIIMCIKM_02074 0.0 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MIIMCIKM_02075 1.2e-49 flaG N flagellar protein FlaG
MIIMCIKM_02076 1.2e-33 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MIIMCIKM_02077 1.1e-77 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MIIMCIKM_02078 3.2e-192 flgL N Belongs to the bacterial flagellin family
MIIMCIKM_02079 5.5e-297 flgK N flagellar hook-associated protein
MIIMCIKM_02081 1.2e-39 N Anti-sigma-28 factor, FlgM
MIIMCIKM_02082 4.5e-76 yvyF S flagellar protein
MIIMCIKM_02083 2.6e-129 comFC S Phosphoribosyl transferase domain
MIIMCIKM_02084 2.3e-187 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MIIMCIKM_02085 7.6e-152 degV S protein conserved in bacteria
MIIMCIKM_02086 1.1e-122 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIIMCIKM_02087 4.1e-201 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MIIMCIKM_02088 6.6e-116 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MIIMCIKM_02089 6.2e-108 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MIIMCIKM_02090 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
MIIMCIKM_02091 4e-151 oppC EP binding-protein-dependent transport systems inner membrane component
MIIMCIKM_02092 1.5e-175 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_02093 3.7e-147 oppF P Belongs to the ABC transporter superfamily
MIIMCIKM_02094 1.3e-193 oppD P Belongs to the ABC transporter superfamily
MIIMCIKM_02095 1.4e-80 asnC K helix_turn_helix ASNC type
MIIMCIKM_02096 1.4e-187 ywtF K Transcriptional regulator
MIIMCIKM_02097 3.9e-92 K Bacterial transcription activator, effector binding domain
MIIMCIKM_02098 2.2e-87
MIIMCIKM_02100 1.9e-30 GK ROK family
MIIMCIKM_02101 2.2e-97 yocH 3.5.1.28 M 3D domain
MIIMCIKM_02102 2e-215 2.3.1.157, 2.7.7.23 JM Bacterial transferase hexapeptide (six repeats)
MIIMCIKM_02103 2.6e-129 K transcriptional
MIIMCIKM_02104 1.7e-139 S carbohydrate derivative metabolic process
MIIMCIKM_02105 2.1e-83 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_02106 6.1e-244 ykoH T Histidine kinase
MIIMCIKM_02107 1.4e-125 ykoI S Peptidase propeptide and YPEB domain
MIIMCIKM_02108 1.1e-85 ykoJ S Peptidase propeptide and YPEB domain
MIIMCIKM_02109 5.4e-19 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MIIMCIKM_02112 3.2e-250 I radical SAM domain protein
MIIMCIKM_02113 5.8e-285 H Involved in the biosynthesis of porphyrin-containing compound
MIIMCIKM_02114 4.3e-12
MIIMCIKM_02115 2.7e-140 yafE Q methyltransferase
MIIMCIKM_02116 6.9e-14 1.2.7.12 S Uncharacterised protein family UPF0066
MIIMCIKM_02117 2.3e-89 1.2.7.12 S Uncharacterised protein family UPF0066
MIIMCIKM_02118 1.9e-223 EGP Major facilitator Superfamily
MIIMCIKM_02119 1e-101 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIIMCIKM_02120 6e-174 wbpP 5.1.3.2, 5.1.3.7 M GDP-mannose 4,6 dehydratase
MIIMCIKM_02121 1.3e-190 M Glycosyl transferases group 1
MIIMCIKM_02122 1.2e-157
MIIMCIKM_02123 1.7e-133 GT2,GT4 M transferase activity, transferring glycosyl groups
MIIMCIKM_02124 9e-175 M transferase activity, transferring glycosyl groups
MIIMCIKM_02125 3.5e-131 M Glycosyl transferase family 2
MIIMCIKM_02126 1.4e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MIIMCIKM_02127 1.5e-25 ybbJ K acetyltransferase
MIIMCIKM_02128 1.7e-251 M Glycosyltransferase like family 2
MIIMCIKM_02129 2.4e-41 S Protein of unknown function (DUF2642)
MIIMCIKM_02130 4.5e-26
MIIMCIKM_02131 1.1e-242 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MIIMCIKM_02132 1.5e-112 ycsK E anatomical structure formation involved in morphogenesis
MIIMCIKM_02133 2.9e-131 K helix_turn_helix isocitrate lyase regulation
MIIMCIKM_02134 2.9e-176 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MIIMCIKM_02135 1.7e-111 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MIIMCIKM_02136 5.7e-227 dgoD 4.2.1.6 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MIIMCIKM_02137 1.1e-155 S Metallo-beta-lactamase superfamily
MIIMCIKM_02138 5.6e-88 S Predicted membrane protein (DUF2243)
MIIMCIKM_02139 5.1e-121 S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
MIIMCIKM_02140 6.5e-243 T COG0642 Signal transduction histidine kinase
MIIMCIKM_02141 1.1e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_02142 9.2e-98 S DinB superfamily
MIIMCIKM_02143 5.4e-62
MIIMCIKM_02144 5.8e-140 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MIIMCIKM_02145 3e-287 malX 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIIMCIKM_02146 2.6e-258 4.3.2.2, 5.5.1.2 F Adenylosuccinate lyase C-terminus
MIIMCIKM_02147 1.6e-118 glvR K Helix-turn-helix domain, rpiR family
MIIMCIKM_02149 2.3e-72 K helix_turn_helix multiple antibiotic resistance protein
MIIMCIKM_02150 4.8e-16
MIIMCIKM_02151 4.5e-16
MIIMCIKM_02153 7.2e-256 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MIIMCIKM_02154 7.7e-140 celG 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
MIIMCIKM_02155 2.2e-254 pagL 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MIIMCIKM_02156 4.2e-127 mngR K UTRA
MIIMCIKM_02157 8.1e-114 S CAAX protease self-immunity
MIIMCIKM_02158 1.8e-193 3.5.1.28 M COG3103 SH3 domain protein
MIIMCIKM_02159 3.2e-166 ydhU P Catalase
MIIMCIKM_02160 1e-150 S Nucleotidyltransferase domain
MIIMCIKM_02161 7.9e-27
MIIMCIKM_02162 5.7e-129 bshB1 S proteins, LmbE homologs
MIIMCIKM_02163 8.7e-201 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MIIMCIKM_02164 1.8e-209 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MIIMCIKM_02165 3.5e-177 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MIIMCIKM_02166 4.9e-151 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MIIMCIKM_02167 3.5e-171 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MIIMCIKM_02168 2.7e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MIIMCIKM_02169 6.2e-179 S Tetratricopeptide repeat
MIIMCIKM_02170 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MIIMCIKM_02171 1.9e-247 mtaD 3.5.4.28, 3.5.4.31 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
MIIMCIKM_02172 7.8e-14
MIIMCIKM_02173 4.2e-22 ypmA S Protein of unknown function (DUF4264)
MIIMCIKM_02174 1.8e-84 ypmB S protein conserved in bacteria
MIIMCIKM_02175 3.4e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MIIMCIKM_02176 1.3e-128 dnaD L DNA replication protein DnaD
MIIMCIKM_02177 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIIMCIKM_02178 0.0 ypbR S Dynamin family
MIIMCIKM_02179 3.4e-160 K AraC-like ligand binding domain
MIIMCIKM_02180 2e-194 dctP G Bacterial extracellular solute-binding protein, family 7
MIIMCIKM_02181 7.8e-91 G Tripartite ATP-independent periplasmic transporters, DctQ component
MIIMCIKM_02182 3.2e-20 G Tripartite ATP-independent periplasmic transporter, DctM component
MIIMCIKM_02183 3.1e-168 G Tripartite ATP-independent periplasmic transporter, DctM component
MIIMCIKM_02184 4.6e-48 uxaA 4.2.1.7 G SAF
MIIMCIKM_02185 7.1e-217 uxaA 4.2.1.7 G D-galactarate dehydratase / Altronate hydrolase, C terminus
MIIMCIKM_02186 1.7e-279 M1-1044 S Belongs to the UPF0061 (SELO) family
MIIMCIKM_02187 5.2e-192 xylR3 2.7.1.2 GK ROK family
MIIMCIKM_02188 3.8e-205 glcP G Major Facilitator Superfamily
MIIMCIKM_02189 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
MIIMCIKM_02190 0.0 2.7.13.3 T Histidine kinase
MIIMCIKM_02191 2.3e-276 araC7 T helix_turn_helix, arabinose operon control protein
MIIMCIKM_02192 3.1e-173 lplB P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02193 8.2e-168 lplC1 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02194 0.0 lplA7 G Bacterial extracellular solute-binding protein
MIIMCIKM_02195 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
MIIMCIKM_02196 2.9e-131 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MIIMCIKM_02197 5.6e-109 J Acetyltransferase (GNAT) domain
MIIMCIKM_02198 1.8e-200 pelE 3.4.11.10, 3.4.11.6, 4.2.2.2 M Pectic acid lyase
MIIMCIKM_02199 7.1e-161 3.2.2.21 K AraC-like ligand binding domain
MIIMCIKM_02200 0.0 K Transcriptional regulator
MIIMCIKM_02201 8.2e-298 G ABC transporter substrate-binding protein
MIIMCIKM_02202 5.7e-180 G COG4209 ABC-type polysaccharide transport system, permease component
MIIMCIKM_02203 1.2e-155 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02204 1.5e-169 E Abhydrolase family
MIIMCIKM_02205 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
MIIMCIKM_02206 3.7e-223 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MIIMCIKM_02207 2.6e-83 G carbohydrate transport
MIIMCIKM_02208 5.1e-125 S Integral membrane protein
MIIMCIKM_02209 4.2e-214 MA20_04465 4.2.3.1 E Pyridoxal-phosphate dependent enzyme
MIIMCIKM_02210 3.9e-142 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
MIIMCIKM_02211 1.1e-242 KT transcriptional regulatory protein
MIIMCIKM_02212 4.2e-275 abgB 3.5.1.47 S amidohydrolase
MIIMCIKM_02213 1.3e-279 abgT H AbgT putative transporter family
MIIMCIKM_02214 9.4e-247 3.5.1.47 S Peptidase dimerisation domain
MIIMCIKM_02215 2.5e-23 C 4Fe-4S binding domain
MIIMCIKM_02216 5.7e-39 S Protein of unknown function (DUF1450)
MIIMCIKM_02217 5.5e-115 sodA 1.15.1.1 P Iron/manganese superoxide dismutases, C-terminal domain
MIIMCIKM_02218 1.2e-117 sufR K Transcriptional regulator
MIIMCIKM_02219 6.7e-257 S Polysaccharide biosynthesis protein
MIIMCIKM_02220 1.2e-151 exoM S Glycosyl transferase family 2
MIIMCIKM_02221 1.8e-201 M Glycosyl transferases group 1
MIIMCIKM_02222 1.2e-55
MIIMCIKM_02223 2.5e-248 M -O-antigen
MIIMCIKM_02224 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MIIMCIKM_02225 7.8e-70
MIIMCIKM_02226 2.7e-140 tuaG GT2 M Glycosyltransferase like family 2
MIIMCIKM_02227 2e-173 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MIIMCIKM_02228 1e-176 S Oxidoreductase family, NAD-binding Rossmann fold
MIIMCIKM_02231 1.1e-17
MIIMCIKM_02234 5.4e-200 UW nuclease activity
MIIMCIKM_02248 3e-40
MIIMCIKM_02249 1.5e-92 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIIMCIKM_02250 4e-110 adaA 3.2.2.21 K Transcriptional regulator
MIIMCIKM_02251 7.4e-177 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MIIMCIKM_02252 2.9e-212 S Oxidoreductase family, NAD-binding Rossmann fold
MIIMCIKM_02253 6.1e-227 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MIIMCIKM_02254 2e-68 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MIIMCIKM_02255 1.7e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
MIIMCIKM_02256 2.6e-106 4.2.1.1 P Reversible hydration of carbon dioxide
MIIMCIKM_02257 3.5e-103 ytqB J Putative rRNA methylase
MIIMCIKM_02259 8.1e-192 yttB EGP Major facilitator Superfamily
MIIMCIKM_02260 1.3e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MIIMCIKM_02261 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MIIMCIKM_02262 1.6e-241 3.5.1.47 S amidohydrolase
MIIMCIKM_02263 4.8e-132 S Protein of unknown function (DUF3100)
MIIMCIKM_02264 6.1e-77 S An automated process has identified a potential problem with this gene model
MIIMCIKM_02265 7.2e-66
MIIMCIKM_02266 3e-208 ytfP S HI0933-like protein
MIIMCIKM_02267 8.2e-229 yhaA1 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MIIMCIKM_02268 4.1e-71 yugU S Uncharacterised protein family UPF0047
MIIMCIKM_02269 1e-167 yvrE G SMP-30/Gluconolaconase/LRE-like region
MIIMCIKM_02270 1.5e-286 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIIMCIKM_02271 9.5e-198 ftsW D Belongs to the SEDS family
MIIMCIKM_02272 6.9e-212 rodA D Belongs to the SEDS family
MIIMCIKM_02273 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MIIMCIKM_02274 1.5e-30 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MIIMCIKM_02275 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MIIMCIKM_02276 4.3e-152 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MIIMCIKM_02277 4.3e-49 K helix_turn_helix, mercury resistance
MIIMCIKM_02278 4.3e-166 ydeE K AraC family transcriptional regulator
MIIMCIKM_02279 3.3e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MIIMCIKM_02280 1.5e-108 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MIIMCIKM_02281 2.9e-64 cidA S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MIIMCIKM_02282 7.3e-100 lrgB M effector of murein hydrolase
MIIMCIKM_02283 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MIIMCIKM_02284 5.2e-219 1.8.1.4 C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MIIMCIKM_02285 1.4e-178 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MIIMCIKM_02286 9.9e-194 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MIIMCIKM_02287 6.6e-213 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MIIMCIKM_02288 4.7e-88 2.7.7.19 J crispr-associated protein
MIIMCIKM_02289 1e-62
MIIMCIKM_02290 1.2e-78 S CRISPR-associated endoribonuclease Cas6
MIIMCIKM_02291 1.4e-263 yeaV M Belongs to the BCCT transporter (TC 2.A.15) family
MIIMCIKM_02293 2.8e-79 yiaB S yiaA/B two helix domain
MIIMCIKM_02296 2.4e-181 K Periplasmic binding protein domain
MIIMCIKM_02297 3.8e-148 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIIMCIKM_02298 1.5e-264 S Tripartite tricarboxylate transporter TctA family
MIIMCIKM_02300 9.3e-178 S Tripartite tricarboxylate transporter family receptor
MIIMCIKM_02301 4.4e-166 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
MIIMCIKM_02302 4e-173 glpX 2.2.1.1, 3.1.3.11, 3.1.3.37 G Bacterial fructose-1,6-bisphosphatase, glpX-encoded
MIIMCIKM_02303 5.2e-113 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dak2
MIIMCIKM_02304 7.9e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MIIMCIKM_02305 9.4e-80 rpiB 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
MIIMCIKM_02306 2.3e-134 K DeoR C terminal sensor domain
MIIMCIKM_02307 5.5e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_02308 1.9e-211 1.1.1.14 E Dehydrogenase
MIIMCIKM_02309 7.2e-239 yoaB EGP Major facilitator Superfamily
MIIMCIKM_02310 4.9e-56 S DUF35 OB-fold domain, acyl-CoA-associated
MIIMCIKM_02311 6.1e-205 2.3.1.16, 2.3.1.9 I Thiolase, C-terminal domain
MIIMCIKM_02312 1.5e-283 MA20_41335 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MIIMCIKM_02313 1.3e-92 S DNA-binding protein with PD1-like DNA-binding motif
MIIMCIKM_02314 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
MIIMCIKM_02315 1.1e-218 siaT_2 G Tripartite ATP-independent periplasmic transporter, DctM component
MIIMCIKM_02316 2.2e-85 dctQ1 G Tripartite ATP-independent periplasmic transporters, DctQ component
MIIMCIKM_02317 5.9e-191 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MIIMCIKM_02318 9.2e-133 K Transcriptional regulator
MIIMCIKM_02319 2.2e-204 S response regulator aspartate phosphatase
MIIMCIKM_02321 2.8e-41 S Protein of unknown function (DUF2642)
MIIMCIKM_02322 1.4e-175 cat P Catalase
MIIMCIKM_02323 2.2e-170 aadK G Streptomycin adenylyltransferase
MIIMCIKM_02324 7e-29
MIIMCIKM_02326 4.9e-134 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIIMCIKM_02327 8.6e-84 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MIIMCIKM_02328 8.3e-108 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MIIMCIKM_02329 1.2e-171 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MIIMCIKM_02330 1.1e-96
MIIMCIKM_02331 3.1e-181 flhF N Flagellar biosynthesis regulator FlhF
MIIMCIKM_02332 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MIIMCIKM_02333 1.6e-191 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MIIMCIKM_02334 1.1e-131 fliR N Flagellar biosynthetic protein FliR
MIIMCIKM_02335 3.6e-39 fliQ N Role in flagellar biosynthesis
MIIMCIKM_02336 9.6e-113 fliP N Plays a role in the flagellum-specific transport system
MIIMCIKM_02337 4.6e-104 fliZ N Flagellar biosynthesis protein, FliO
MIIMCIKM_02338 4.2e-59 cheY T cheY-homologous receiver domain
MIIMCIKM_02339 5.4e-212 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MIIMCIKM_02340 3.6e-177 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MIIMCIKM_02341 6.3e-70 fliL N Controls the rotational direction of flagella during chemotaxis
MIIMCIKM_02342 4.9e-28 flbD N protein, possibly involved in motility
MIIMCIKM_02343 1.6e-146 flgG N Flagellar basal body rod
MIIMCIKM_02344 6.2e-73 flgD N Flagellar basal body rod modification protein
MIIMCIKM_02345 1.3e-269 N Flagellar hook-length control protein FliK
MIIMCIKM_02347 8.2e-65 fliJ N bacterial-type flagellum organization
MIIMCIKM_02348 6.8e-248 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MIIMCIKM_02349 2.3e-78 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MIIMCIKM_02350 1.5e-175 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MIIMCIKM_02351 3.4e-246 fliF N The M ring may be actively involved in energy transduction
MIIMCIKM_02352 1.7e-42 fliE N Flagellar hook-basal body
MIIMCIKM_02353 8.8e-75 flgC N Belongs to the flagella basal body rod proteins family
MIIMCIKM_02354 1.7e-66 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MIIMCIKM_02355 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MIIMCIKM_02356 1.8e-227 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MIIMCIKM_02357 1.4e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MIIMCIKM_02358 4e-167 xerC L tyrosine recombinase XerC
MIIMCIKM_02359 7.2e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MIIMCIKM_02360 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIIMCIKM_02361 5.6e-166 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MIIMCIKM_02362 9.7e-169 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MIIMCIKM_02363 1.1e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MIIMCIKM_02364 1.5e-22 ylqH S FlhB HrpN YscU SpaS Family
MIIMCIKM_02366 2.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MIIMCIKM_02367 1.8e-102 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MIIMCIKM_02368 6.1e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MIIMCIKM_02369 3.3e-11 yphA
MIIMCIKM_02370 2.6e-203 rpsA 1.17.7.4 J Ribosomal protein S1
MIIMCIKM_02371 2.3e-107 plsC 2.3.1.51, 2.7.4.25 I 1-acyl-sn-glycerol-3-phosphate acyltransferase
MIIMCIKM_02372 2.4e-131 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MIIMCIKM_02373 5.5e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MIIMCIKM_02374 3e-167 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MIIMCIKM_02375 0.0 metH 2.1.1.13 E Methionine synthase
MIIMCIKM_02376 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MIIMCIKM_02377 8.8e-209 metB 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
MIIMCIKM_02378 2.4e-25
MIIMCIKM_02379 2.6e-112 prsW S Involved in the degradation of specific anti-sigma factors
MIIMCIKM_02380 7.5e-180 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MIIMCIKM_02381 5e-182 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MIIMCIKM_02382 5.5e-239 gdhA 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MIIMCIKM_02383 6.9e-192
MIIMCIKM_02384 9.6e-272 T PhoQ Sensor
MIIMCIKM_02385 5.3e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_02386 1.5e-109 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MIIMCIKM_02387 7.1e-172 merR K MerR family transcriptional regulator
MIIMCIKM_02388 2e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
MIIMCIKM_02389 4.2e-225 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MIIMCIKM_02391 3.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MIIMCIKM_02392 5.6e-197 cpoA GT4 M Glycosyl transferases group 1
MIIMCIKM_02393 1.2e-227 mgs 2.4.1.337 GT4 M Glycosyl Transferase
MIIMCIKM_02395 7e-40 sinR K Helix-turn-helix XRE-family like proteins
MIIMCIKM_02396 4.4e-52 K Helix-turn-helix XRE-family like proteins
MIIMCIKM_02397 3e-08 ypbF S Protein of unknown function (DUF2663)
MIIMCIKM_02399 6.8e-104 ypbD S metal-dependent membrane protease
MIIMCIKM_02400 4.8e-274 recQ 3.6.4.12 L DNA helicase
MIIMCIKM_02401 7.5e-61 V HNH endonuclease
MIIMCIKM_02402 6.6e-88 yokH G SMI1 / KNR4 family
MIIMCIKM_02403 3.5e-07 S Protein of unknown function (DUF3006)
MIIMCIKM_02404 1.3e-68 L Metallo-beta-lactamase superfamily
MIIMCIKM_02406 3.4e-30
MIIMCIKM_02407 3.5e-39 gepA S Protein of unknown function (DUF4065)
MIIMCIKM_02408 6e-60
MIIMCIKM_02410 3.9e-55 MV Ami_2
MIIMCIKM_02411 1.1e-22 S Bacteriophage A118-like holin, Hol118
MIIMCIKM_02412 6.2e-106 S response regulator aspartate phosphatase
MIIMCIKM_02414 1.8e-196 UW nuclease activity
MIIMCIKM_02416 2.6e-84 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIIMCIKM_02417 3.6e-23 S Bacteriophage A118-like holin, Hol118
MIIMCIKM_02418 4.6e-20 xhlA S Haemolysin XhlA
MIIMCIKM_02419 2.7e-16
MIIMCIKM_02420 4.8e-130 S outer membrane
MIIMCIKM_02423 3.1e-42 S peptidoglycan catabolic process
MIIMCIKM_02424 4.2e-31 S Phage tail protein
MIIMCIKM_02425 8.1e-82 D Phage tail tape measure protein TP901
MIIMCIKM_02426 9e-22 S Phage tail assembly chaperone protein, TAC
MIIMCIKM_02427 2.2e-38 N domain, Protein
MIIMCIKM_02428 9.1e-18 S Protein of unknown function (DUF3168)
MIIMCIKM_02429 2.6e-28 S Bacteriophage HK97-gp10, putative tail-component
MIIMCIKM_02430 4.2e-08
MIIMCIKM_02431 2e-20 S Phage gp6-like head-tail connector protein
MIIMCIKM_02433 1.3e-137 S Phage major capsid protein E
MIIMCIKM_02434 2.1e-37
MIIMCIKM_02435 7.9e-50 S Domain of unknown function (DUF4355)
MIIMCIKM_02437 2.2e-59 S Phage Mu protein F like protein
MIIMCIKM_02438 3.5e-146 S Phage portal protein, SPP1 Gp6-like
MIIMCIKM_02439 8.7e-186 ps334 S Terminase-like family
MIIMCIKM_02440 1.5e-75 xtmA L Terminase small subunit
MIIMCIKM_02441 6.2e-99 S Protein of unknown function (DUF3800)
MIIMCIKM_02442 1e-59
MIIMCIKM_02443 2.1e-22
MIIMCIKM_02445 3.6e-57
MIIMCIKM_02446 9.6e-80 S SMI1-KNR4 cell-wall
MIIMCIKM_02447 6.9e-49
MIIMCIKM_02448 2.6e-64
MIIMCIKM_02449 1.2e-55
MIIMCIKM_02451 2.2e-78
MIIMCIKM_02452 3.1e-36 S DNA/RNA non-specific endonuclease
MIIMCIKM_02453 8.3e-26 S DNA/RNA non-specific endonuclease
MIIMCIKM_02454 1.9e-67 S Protein of unknown function, DUF600
MIIMCIKM_02455 2.8e-79
MIIMCIKM_02456 2.8e-84 S Protein of unknown function (DUF1569)
MIIMCIKM_02457 1.5e-76 yuxK S protein conserved in bacteria
MIIMCIKM_02458 8.9e-95 ykkA S Protein of unknown function (DUF664)
MIIMCIKM_02459 5.5e-272 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIIMCIKM_02460 3e-105 argO S Lysine exporter protein LysE YggA
MIIMCIKM_02461 7.2e-74 lrpC K helix_turn_helix ASNC type
MIIMCIKM_02462 7.1e-74 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIIMCIKM_02463 3.8e-257 T His Kinase A (phosphoacceptor) domain
MIIMCIKM_02464 3.1e-124 K Transcriptional regulatory protein, C terminal
MIIMCIKM_02465 1.2e-135 mutG S ABC-2 family transporter protein
MIIMCIKM_02466 2.4e-125 spaE S ABC-2 family transporter protein
MIIMCIKM_02467 3.9e-125 mutF V ABC transporter, ATP-binding protein
MIIMCIKM_02468 1.1e-172 yisR1 K AraC-like ligand binding domain
MIIMCIKM_02469 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
MIIMCIKM_02470 1.8e-272 G Bacterial extracellular solute-binding protein
MIIMCIKM_02471 1.5e-172 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02472 5.1e-153 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02473 2.2e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
MIIMCIKM_02474 4.3e-68 K Helix-turn-helix XRE-family like proteins
MIIMCIKM_02475 5.5e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MIIMCIKM_02476 2.1e-299 E COG0747 ABC-type dipeptide transport system, periplasmic component
MIIMCIKM_02477 2.5e-161 nhaR K LysR substrate binding domain
MIIMCIKM_02478 8.9e-256 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MIIMCIKM_02479 3.2e-162 yocS S -transporter
MIIMCIKM_02480 4.6e-263 dld 1.1.1.303, 1.1.1.4, 1.1.2.4, 1.1.3.15 C Glycolate oxidase subunit
MIIMCIKM_02481 7.9e-307 T COG0642 Signal transduction histidine kinase
MIIMCIKM_02482 2.7e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MIIMCIKM_02483 1.8e-195 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
MIIMCIKM_02484 1.2e-133 cysT O COG0555 ABC-type sulfate transport system, permease component
MIIMCIKM_02485 2.9e-134 cysW P COG4208 ABC-type sulfate transport system, permease component
MIIMCIKM_02486 6.6e-201 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MIIMCIKM_02487 4.6e-196
MIIMCIKM_02488 7.4e-141 S transport system, ATPase component
MIIMCIKM_02489 2.7e-172 S Belongs to the binding-protein-dependent transport system permease family
MIIMCIKM_02490 2.1e-177 S transport system, periplasmic component
MIIMCIKM_02491 1.8e-229 S Sulphur transport
MIIMCIKM_02492 1.8e-103 ynaD J Acetyltransferase (GNAT) domain
MIIMCIKM_02493 4.1e-65 XK27_04860 S Domain of unknown function (DUF4440)
MIIMCIKM_02494 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
MIIMCIKM_02495 1.2e-183 dppD P Belongs to the ABC transporter superfamily
MIIMCIKM_02496 4.9e-190 appF E Belongs to the ABC transporter superfamily
MIIMCIKM_02497 3.2e-303 E COG0747 ABC-type dipeptide transport system, periplasmic component
MIIMCIKM_02498 2.6e-183 dppB EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_02499 2.2e-160 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_02500 2.7e-165 3.4.11.5 I Alpha/beta hydrolase family
MIIMCIKM_02501 1.8e-65 gpm5 3.1.3.3, 5.4.2.11 G alpha-ribazole phosphatase activity
MIIMCIKM_02502 1.2e-106 tetR K Bacterial regulatory proteins, tetR family
MIIMCIKM_02503 1.3e-246 matE V MatE
MIIMCIKM_02504 3.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIIMCIKM_02505 2.3e-142 phnE 3.6.1.63 P ABC transporter
MIIMCIKM_02506 2.9e-137 phnE 3.6.1.63 P ABC transporter
MIIMCIKM_02507 7.5e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MIIMCIKM_02508 1.6e-171 phnD P Phosphonate ABC transporter
MIIMCIKM_02509 0.0 uvrD 3.6.4.12 L DNA helicase
MIIMCIKM_02510 2e-308 yfiB3 V ABC transporter
MIIMCIKM_02511 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIIMCIKM_02512 2e-233 pilS 2.7.13.3 T Histidine kinase
MIIMCIKM_02513 1e-179 sftA D Belongs to the FtsK SpoIIIE SftA family
MIIMCIKM_02514 6.9e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MIIMCIKM_02515 4.3e-63 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MIIMCIKM_02516 3.9e-16 XK27_07760 S COG4980 Gas vesicle protein
MIIMCIKM_02517 4.1e-198 aroA 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MIIMCIKM_02518 2.3e-185 ccpA K catabolite control protein A
MIIMCIKM_02519 1.2e-238 acuC BQ histone deacetylase
MIIMCIKM_02520 4e-116 acuB S Acetoin utilization protein AcuB
MIIMCIKM_02521 8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MIIMCIKM_02522 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MIIMCIKM_02523 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M COG0744 Membrane carboxypeptidase (penicillin-binding protein)
MIIMCIKM_02524 1.1e-234 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIIMCIKM_02525 1.3e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MIIMCIKM_02526 2.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MIIMCIKM_02527 3.6e-114 yttP K Transcriptional regulator
MIIMCIKM_02528 1.6e-148 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MIIMCIKM_02529 1.3e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MIIMCIKM_02530 5.3e-209 iscS2 2.8.1.7 E Cysteine desulfurase
MIIMCIKM_02531 1.5e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIIMCIKM_02532 8.1e-28 sspB S spore protein
MIIMCIKM_02533 3.5e-180 sppA OU signal peptide peptidase SppA
MIIMCIKM_02534 1.7e-99 yteJ S RDD family
MIIMCIKM_02535 5.4e-124 ytfI S Protein of unknown function (DUF2953)
MIIMCIKM_02536 8.4e-75 ytfJ S Sporulation protein YtfJ
MIIMCIKM_02537 2.4e-196 ywoG EGP Major facilitator Superfamily
MIIMCIKM_02538 2.7e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MIIMCIKM_02539 1.4e-181 ytxK 2.1.1.72 L DNA methylase
MIIMCIKM_02540 2.3e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MIIMCIKM_02541 8.1e-171 yhaM S 3'-5' exoribonuclease yhaM
MIIMCIKM_02542 2.2e-12 S EcsC protein family
MIIMCIKM_02543 4.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MIIMCIKM_02544 2.2e-238 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MIIMCIKM_02545 1.3e-87 K Acetyltransferase (GNAT) domain
MIIMCIKM_02546 2.6e-77 S Protein of unknown function (DUF4064)
MIIMCIKM_02547 9e-264 6.3.1.2 E Glutamine synthetase, catalytic domain
MIIMCIKM_02548 7.9e-193 I Fatty acid desaturase
MIIMCIKM_02549 7.1e-236 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E methionine gamma-lyase
MIIMCIKM_02550 2.4e-130 S B3/4 domain
MIIMCIKM_02551 4.1e-278 gntR9 K Alanine-glyoxylate amino-transferase
MIIMCIKM_02552 3.4e-124 azlC E AzlC protein
MIIMCIKM_02553 3.4e-47 S Branched-chain amino acid transport protein (AzlD)
MIIMCIKM_02554 1.4e-278 hutH 4.3.1.3 E Histidine ammonia-lyase
MIIMCIKM_02555 8.9e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MIIMCIKM_02556 1.7e-233 BH2250 S protein conserved in bacteria
MIIMCIKM_02557 3e-138 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIIMCIKM_02558 1.4e-179 abrB S Pfam:AmoA
MIIMCIKM_02559 1.3e-229 amtB P Ammonium transporter
MIIMCIKM_02560 6.1e-171 2.7.7.7 T Putative nucleotidyltransferase substrate binding domain
MIIMCIKM_02561 3.2e-135 dnaQ2 2.7.7.7 L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
MIIMCIKM_02562 5.2e-47 S Family of unknown function (DUF5327)
MIIMCIKM_02563 8.4e-271 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIIMCIKM_02564 2.5e-112 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIIMCIKM_02565 1.3e-58 ywdK S small membrane protein
MIIMCIKM_02566 6.1e-79 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MIIMCIKM_02567 1.3e-78 cwlJ 3.5.1.28 M Cell wall
MIIMCIKM_02568 8.4e-131
MIIMCIKM_02569 1.2e-62 K helix_turn_helix gluconate operon transcriptional repressor
MIIMCIKM_02570 1.4e-161 natA1 V ABC transporter
MIIMCIKM_02571 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
MIIMCIKM_02572 1.3e-184 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MIIMCIKM_02573 5.8e-48
MIIMCIKM_02574 2e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MIIMCIKM_02575 1.2e-145 ywfI C May function as heme-dependent peroxidase
MIIMCIKM_02576 3e-142 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
MIIMCIKM_02577 2.9e-182 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MIIMCIKM_02578 4.8e-151 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MIIMCIKM_02579 1.2e-62 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MIIMCIKM_02580 1.7e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIIMCIKM_02581 1.6e-112 metI P COG2011 ABC-type metal ion transport system, permease component
MIIMCIKM_02582 3.3e-152 P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
MIIMCIKM_02583 9.7e-208 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
MIIMCIKM_02585 9.5e-119 ydiL S CAAX protease self-immunity
MIIMCIKM_02586 5.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MIIMCIKM_02587 2.6e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MIIMCIKM_02588 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
MIIMCIKM_02589 4.8e-73 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MIIMCIKM_02590 1.4e-41 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
MIIMCIKM_02591 5e-224 ulaA S PTS system ascorbate-specific transporter subunit IIC
MIIMCIKM_02592 1.9e-130 S carbohydrate derivative metabolic process
MIIMCIKM_02593 3.9e-122 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MIIMCIKM_02594 3.2e-152 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MIIMCIKM_02595 6.6e-273 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MIIMCIKM_02596 9.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MIIMCIKM_02597 1.4e-104 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MIIMCIKM_02598 6.7e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MIIMCIKM_02599 6.7e-187 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MIIMCIKM_02600 1.2e-241 moeA 2.10.1.1 H molybdopterin
MIIMCIKM_02601 1.7e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MIIMCIKM_02602 1.1e-74 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MIIMCIKM_02603 5.7e-36 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MIIMCIKM_02604 9.9e-141 focA P Formate/nitrite transporter
MIIMCIKM_02605 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MIIMCIKM_02606 1.2e-109 yjgD S Protein of unknown function (DUF1641)
MIIMCIKM_02607 1.2e-137 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MIIMCIKM_02608 1.1e-86 MA20_19235 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MIIMCIKM_02611 0.0 yfhO S Bacterial membrane protein YfhO
MIIMCIKM_02612 6.2e-70 wxcN GT2 S GtrA-like protein
MIIMCIKM_02613 3.6e-182 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MIIMCIKM_02614 1.6e-154 S Haloacid dehalogenase-like hydrolase
MIIMCIKM_02615 5.2e-145
MIIMCIKM_02616 3.3e-239 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MIIMCIKM_02617 5.2e-300 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MIIMCIKM_02618 9.1e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MIIMCIKM_02619 4.1e-220 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MIIMCIKM_02620 1e-187 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MIIMCIKM_02621 4.2e-181 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MIIMCIKM_02622 6.9e-206 S response regulator aspartate phosphatase
MIIMCIKM_02624 2.3e-40 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIIMCIKM_02625 1e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MIIMCIKM_02626 7e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MIIMCIKM_02627 6.6e-234 E Peptidase dimerisation domain
MIIMCIKM_02628 1.5e-56 S Domain of unknown function (DUF4870)
MIIMCIKM_02629 5.4e-217 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MIIMCIKM_02630 8.7e-108 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MIIMCIKM_02631 3.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MIIMCIKM_02632 8.7e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MIIMCIKM_02633 5e-38 crh G Phosphocarrier protein Chr
MIIMCIKM_02634 4.3e-178 whiA K May be required for sporulation
MIIMCIKM_02635 1.9e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MIIMCIKM_02636 5.2e-167 rapZ S Displays ATPase and GTPase activities
MIIMCIKM_02637 5.7e-91 yvcI 3.6.1.55 F Nudix hydrolase
MIIMCIKM_02638 5.9e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MIIMCIKM_02639 3e-198 S COG0457 FOG TPR repeat
MIIMCIKM_02640 5.3e-242 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MIIMCIKM_02641 1.5e-146 yobR 2.3.1.1 K FR47-like protein
MIIMCIKM_02642 3.3e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MIIMCIKM_02643 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MIIMCIKM_02644 2.7e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MIIMCIKM_02645 2.2e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MIIMCIKM_02646 4.2e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MIIMCIKM_02647 6.2e-230 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIIMCIKM_02648 2.1e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MIIMCIKM_02649 3.5e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MIIMCIKM_02650 2.9e-240 pepF E oligoendopeptidase
MIIMCIKM_02651 0.0 clpE O Belongs to the ClpA ClpB family
MIIMCIKM_02652 1e-81 cwlM 3.5.1.28 M COG3103 SH3 domain protein
MIIMCIKM_02653 4e-47
MIIMCIKM_02654 5.6e-294 K Mga helix-turn-helix domain
MIIMCIKM_02657 2.6e-66 S YolD-like protein
MIIMCIKM_02658 1e-221 P Protein of unknown function (DUF418)
MIIMCIKM_02659 1e-226 GK ROK family
MIIMCIKM_02660 1.1e-242 cycB_2 G Bacterial extracellular solute-binding protein
MIIMCIKM_02661 4.1e-170 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02662 2.1e-146 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02663 7.2e-189 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_02664 2.8e-185 S Oxidoreductase family, NAD-binding Rossmann fold
MIIMCIKM_02665 1.7e-156 5.1.3.22, 5.3.1.5 G Xylose isomerase-like TIM barrel
MIIMCIKM_02666 9.9e-182 S Alpha/beta hydrolase family
MIIMCIKM_02667 1.2e-154 K LysR substrate binding domain
MIIMCIKM_02668 8.9e-123 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MIIMCIKM_02669 2.3e-229 EGP Major facilitator Superfamily
MIIMCIKM_02670 4e-249 EGP Major facilitator Superfamily
MIIMCIKM_02671 2.2e-111 K Bacterial transcriptional repressor C-terminal
MIIMCIKM_02672 8.1e-148 2.1.1.144, 2.1.1.197 S Methyltransferase domain
MIIMCIKM_02673 2.2e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MIIMCIKM_02674 7.4e-172 fhuD P Periplasmic binding protein
MIIMCIKM_02675 2.1e-172 fhuG 3.6.3.34 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIIMCIKM_02676 8.1e-54 isdG 1.14.99.48, 1.14.99.57 C Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
MIIMCIKM_02677 1.8e-111 isdC M NEAr Transporter domain
MIIMCIKM_02678 0.0 M Cell surface protein
MIIMCIKM_02679 9.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MIIMCIKM_02680 4.4e-291 M Glycosyltransferase like family 2
MIIMCIKM_02681 0.0 tagF 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MIIMCIKM_02682 9e-71 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MIIMCIKM_02683 6.1e-137 2.7.8.34 I CDP-alcohol phosphatidyltransferase
MIIMCIKM_02684 5.4e-236 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MIIMCIKM_02685 1.8e-251 wcaJ M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MIIMCIKM_02686 2.7e-199 exoA M Glycosyltransferase like family 2
MIIMCIKM_02687 3.3e-138 E lipolytic protein G-D-S-L family
MIIMCIKM_02688 4.2e-65 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MIIMCIKM_02689 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIIMCIKM_02690 1.2e-191 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MIIMCIKM_02691 3e-113 ymaB S MutT family
MIIMCIKM_02692 3e-101 pncA Q COG1335 Amidases related to nicotinamidase
MIIMCIKM_02693 1.2e-26
MIIMCIKM_02694 1.1e-218 yaaH M Glycoside Hydrolase Family
MIIMCIKM_02695 5.8e-135 IQ Enoyl-(Acyl carrier protein) reductase
MIIMCIKM_02696 2.4e-302 cscA 3.2.1.26, 3.2.1.80 GH32 G invertase
MIIMCIKM_02697 0.0 sacC 3.2.1.26, 3.2.1.80 GH32 G invertase
MIIMCIKM_02698 0.0 lplA5 G Bacterial extracellular solute-binding protein
MIIMCIKM_02699 5e-162 lplC7 G COG0395 ABC-type sugar transport system, permease component
MIIMCIKM_02700 1.1e-175 lplB7 G COG4209 ABC-type polysaccharide transport system, permease component
MIIMCIKM_02702 2e-183 scrR K transcriptional
MIIMCIKM_02704 1.3e-114
MIIMCIKM_02705 5.3e-206 msmX E ABC transporter
MIIMCIKM_02706 1.3e-157 araQ P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02707 8.4e-165 araP G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02708 1.1e-172 XK27_06795 K sequence-specific DNA binding
MIIMCIKM_02710 0.0 spaB S Lantibiotic dehydratase, C terminus
MIIMCIKM_02711 1.9e-261 spaC1 V Lanthionine synthetase C-like protein
MIIMCIKM_02712 2.6e-103 4.1.1.36, 6.3.2.5 H Flavoprotein
MIIMCIKM_02713 2e-129 V AAA domain, putative AbiEii toxin, Type IV TA system
MIIMCIKM_02714 4.4e-136 S ABC-2 family transporter protein
MIIMCIKM_02715 1.8e-131
MIIMCIKM_02716 1.8e-124 T Transcriptional regulatory protein, C terminal
MIIMCIKM_02717 1.6e-255 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MIIMCIKM_02718 5e-55 comEA L Helix-hairpin-helix motif
MIIMCIKM_02719 5e-103 2.7.7.7 L Domain of unknown function (DUF4357)
MIIMCIKM_02720 5.7e-31
MIIMCIKM_02721 3.5e-26 K Cro/C1-type HTH DNA-binding domain
MIIMCIKM_02722 1.5e-39 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
MIIMCIKM_02723 3e-31 fic S Fic/DOC family
MIIMCIKM_02727 6.9e-173 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MIIMCIKM_02728 2.8e-182 rbsR K transcriptional
MIIMCIKM_02729 2.2e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIIMCIKM_02730 6.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MIIMCIKM_02731 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MIIMCIKM_02732 1.7e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
MIIMCIKM_02733 1.7e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MIIMCIKM_02734 5.7e-77
MIIMCIKM_02735 1.8e-71 K Transcriptional regulator
MIIMCIKM_02736 4.1e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIIMCIKM_02737 2.7e-61 K MerR, DNA binding
MIIMCIKM_02738 3.9e-104
MIIMCIKM_02740 1.3e-54 K Helix-turn-helix XRE-family like proteins
MIIMCIKM_02741 1e-102 3.4.22.70 M Sortase family
MIIMCIKM_02742 0.0 M1-568 M cell wall anchor domain
MIIMCIKM_02743 2.1e-80 T Bacterial transcriptional activator domain
MIIMCIKM_02744 5.3e-216 M1-573 T PhoQ Sensor
MIIMCIKM_02745 8.8e-15
MIIMCIKM_02746 4.4e-186 G phosphotransferase system
MIIMCIKM_02747 2.6e-198 rspA 4.2.1.8 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MIIMCIKM_02748 5.7e-92 K Helix-turn-helix domain
MIIMCIKM_02749 5.3e-24 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIIMCIKM_02750 7.1e-297 ramA 3.2.1.40 G Alpha-L-rhamnosidase
MIIMCIKM_02751 2.3e-98 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02752 5.2e-119 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02753 2.2e-134 G Bacterial extracellular solute-binding protein
MIIMCIKM_02755 8.9e-40 FT AraC family transcriptional regulator
MIIMCIKM_02756 6.1e-124 2.7.13.3 T Histidine kinase
MIIMCIKM_02757 3.1e-86 S Sulfite exporter TauE/SafE
MIIMCIKM_02758 2.4e-119 K Transcriptional regulator
MIIMCIKM_02759 0.0 bglX 3.2.1.21 GH3 G Belongs to the glycosyl hydrolase 3 family
MIIMCIKM_02760 1.7e-257 scrA5 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIIMCIKM_02761 6.7e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIIMCIKM_02762 5.1e-95
MIIMCIKM_02763 9.4e-292 cstA T Carbon starvation protein
MIIMCIKM_02764 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MIIMCIKM_02765 1.6e-258 sdcS P Sodium:sulfate symporter transmembrane region
MIIMCIKM_02766 1.3e-185 yccF K SEC-C motif
MIIMCIKM_02767 4.2e-53 S Regulatory protein YrvL
MIIMCIKM_02768 0.0 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 F Belongs to the 5'-nucleotidase family
MIIMCIKM_02769 6.9e-273 MA20_17540 P secondary active sulfate transmembrane transporter activity
MIIMCIKM_02770 3.8e-105 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MIIMCIKM_02771 4.9e-48
MIIMCIKM_02772 6.1e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
MIIMCIKM_02773 2.9e-110 M Peptidoglycan-binding domain 1 protein
MIIMCIKM_02775 4e-102 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MIIMCIKM_02776 1e-142 adcA P Belongs to the bacterial solute-binding protein 9 family
MIIMCIKM_02777 7.7e-56 yxjI S LURP-one-related
MIIMCIKM_02778 5.6e-144 gspA M Glycosyl transferase family 8
MIIMCIKM_02779 1.5e-184 V ABC-2 type transporter
MIIMCIKM_02780 5.5e-231 V ABC-2 family transporter protein
MIIMCIKM_02781 3.5e-129 V COG1131 ABC-type multidrug transport system, ATPase component
MIIMCIKM_02782 3e-86 thuA G Trehalose utilisation
MIIMCIKM_02783 2.4e-192 S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_02784 1.3e-220 V Belongs to the UPF0214 family
MIIMCIKM_02786 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MIIMCIKM_02787 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIIMCIKM_02788 3.8e-221 1.1.1.3 E homoserine dehydrogenase
MIIMCIKM_02789 4e-50
MIIMCIKM_02790 3.6e-218 yxjG 2.1.1.14 E Methionine synthase
MIIMCIKM_02791 6.3e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MIIMCIKM_02792 1.5e-107 rsfA S Transcriptional regulator
MIIMCIKM_02793 1.2e-233 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MIIMCIKM_02794 1.6e-70 cymR K Transcriptional regulator
MIIMCIKM_02795 1.7e-215 iscS 2.8.1.7 E Cysteine desulfurase
MIIMCIKM_02796 3.9e-217 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MIIMCIKM_02797 2.3e-39 S COG0457 FOG TPR repeat
MIIMCIKM_02798 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MIIMCIKM_02799 9.3e-83 yrrD S protein conserved in bacteria
MIIMCIKM_02800 2.1e-30 yrzR
MIIMCIKM_02801 2.2e-188 yrrI S AI-2E family transporter
MIIMCIKM_02802 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIIMCIKM_02803 1.9e-43 yrzL S Belongs to the UPF0297 family
MIIMCIKM_02804 6.1e-73 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MIIMCIKM_02805 4.1e-25 yrzB S Belongs to the UPF0473 family
MIIMCIKM_02806 2.6e-211 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIIMCIKM_02807 3.6e-117 yrrM 2.1.1.104 S O-methyltransferase
MIIMCIKM_02808 1.4e-113 udk 2.7.1.48 F Cytidine monophosphokinase
MIIMCIKM_02809 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MIIMCIKM_02810 8.7e-12 S Protein of unknown function (DUF1510)
MIIMCIKM_02811 1.7e-212 ligD 6.5.1.1 L ATP-dependent DNA ligase
MIIMCIKM_02812 2.1e-88 amyD G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02813 4e-153 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02814 3.8e-108 S Protein of unknown function, DUF624
MIIMCIKM_02815 2.4e-175 M1-640 K Transcriptional regulator
MIIMCIKM_02816 1.1e-169 rhaR1 K AraC-like ligand binding domain
MIIMCIKM_02817 1.3e-140 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MIIMCIKM_02818 3.6e-216 egsA 1.1.1.261 C Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MIIMCIKM_02819 7.5e-137 araD 4.1.2.17, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MIIMCIKM_02820 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MIIMCIKM_02821 2.2e-287 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MIIMCIKM_02822 1.2e-197 chvE G ABC transporter
MIIMCIKM_02823 4.8e-285 araG 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MIIMCIKM_02824 1.1e-198 gguB G Belongs to the binding-protein-dependent transport system permease family
MIIMCIKM_02825 2e-299 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MIIMCIKM_02826 2.7e-51 V ATPases associated with a variety of cellular activities
MIIMCIKM_02827 3.7e-27
MIIMCIKM_02828 2.4e-81 S Putative small multi-drug export protein
MIIMCIKM_02829 2.1e-115 V Transport permease protein
MIIMCIKM_02830 2.5e-186 KTV LytTr DNA-binding domain
MIIMCIKM_02831 3.8e-48 sugE P Small Multidrug Resistance protein
MIIMCIKM_02832 3.2e-59 sugE P Small Multidrug Resistance protein
MIIMCIKM_02833 2.3e-99 yvdT K Transcriptional regulator
MIIMCIKM_02834 5.7e-245 EGP Major Facilitator Superfamily
MIIMCIKM_02835 2.2e-137 iolR K COG1349 Transcriptional regulators of sugar metabolism
MIIMCIKM_02836 4.7e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIIMCIKM_02837 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MIIMCIKM_02838 3.4e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MIIMCIKM_02839 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MIIMCIKM_02840 2.7e-179 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MIIMCIKM_02841 3.6e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MIIMCIKM_02842 1.3e-162 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MIIMCIKM_02843 1.7e-190 yisS 1.1.1.370 S Oxidoreductase family, NAD-binding Rossmann fold
MIIMCIKM_02844 4e-271 yidK S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIIMCIKM_02845 3.3e-104 S Protein of unknown function (DUF421)
MIIMCIKM_02846 8.1e-246 metY 2.5.1.49 E O-acetylhomoserine
MIIMCIKM_02847 1.4e-64 S Putative zinc- or iron-chelating domain
MIIMCIKM_02848 1.2e-141 bxlB G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02849 2.9e-165 bxlC G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_02850 7.1e-250 bxlD G Bacterial extracellular solute-binding protein
MIIMCIKM_02851 1.1e-161 K AraC-like ligand binding domain
MIIMCIKM_02852 4.3e-194 yjjN E Alcohol dehydrogenase GroES-like domain
MIIMCIKM_02853 4.2e-189 dctP G Bacterial extracellular solute-binding protein, family 7
MIIMCIKM_02854 1.6e-82 G Tripartite ATP-independent periplasmic transporters, DctQ component
MIIMCIKM_02855 3.3e-223 G Tripartite ATP-independent periplasmic transporter, DctM component
MIIMCIKM_02856 5.6e-291 uxaA 4.2.1.7 G Altronate
MIIMCIKM_02857 3.8e-295 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MIIMCIKM_02858 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 K transcriptional regulator, MtlR
MIIMCIKM_02859 2.3e-159 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MIIMCIKM_02860 5.2e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MIIMCIKM_02861 1.1e-47 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
MIIMCIKM_02862 3.3e-168 fruA2 G Phosphotransferase System
MIIMCIKM_02863 1.6e-96 5.3.1.15 S Cupin 2, conserved barrel domain protein
MIIMCIKM_02865 2.8e-268 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MIIMCIKM_02866 3e-159 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MIIMCIKM_02867 3.1e-104 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MIIMCIKM_02868 1.4e-256 KT Transcriptional regulator
MIIMCIKM_02869 8.4e-238 E Acyclic terpene utilisation family protein AtuA
MIIMCIKM_02870 3e-53
MIIMCIKM_02871 5.8e-228 C Citrate transporter
MIIMCIKM_02872 1.7e-254 NT chemotaxis protein
MIIMCIKM_02873 1.6e-239 V MatE
MIIMCIKM_02874 4.7e-12
MIIMCIKM_02875 7e-98 S Tetratricopeptide repeat
MIIMCIKM_02876 1e-49 3.6.1.55 F NUDIX domain
MIIMCIKM_02877 3.5e-97
MIIMCIKM_02878 2.2e-293 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MIIMCIKM_02879 2.4e-130 T Response regulator receiver domain
MIIMCIKM_02880 2.4e-229 citH C Citrate transporter
MIIMCIKM_02882 7.1e-231 lacE3 G PFAM extracellular solute-binding protein family 1
MIIMCIKM_02883 1.4e-159 cebF P PFAM binding-protein-dependent transport systems inner membrane component
MIIMCIKM_02884 6.7e-153 araQ5 P PFAM binding-protein-dependent transport systems inner membrane component
MIIMCIKM_02885 1.5e-218 gntP EG GntP family permease
MIIMCIKM_02886 2.5e-186 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
MIIMCIKM_02887 6.8e-237 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
MIIMCIKM_02888 7.5e-135 ygbI K DeoR C terminal sensor domain
MIIMCIKM_02889 4.8e-282 gerKA EG Spore germination protein
MIIMCIKM_02890 1.5e-222 gerKC S spore germination
MIIMCIKM_02892 2.2e-210 E Spore germination protein
MIIMCIKM_02893 9.5e-53 S Domain of unknown function (DUF4352)
MIIMCIKM_02894 1.5e-160 kynA 1.13.11.11 E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
MIIMCIKM_02895 2.4e-118 kynB 3.5.1.9 S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MIIMCIKM_02896 1.8e-250 kynU 3.7.1.3 E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
MIIMCIKM_02897 5.7e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MIIMCIKM_02898 1e-226 ybfB G COG0477 Permeases of the major facilitator superfamily
MIIMCIKM_02899 9.3e-56 S Protein of unknown function (DUF1093)
MIIMCIKM_02900 5.1e-42 S Family of unknown function (DUF5391)
MIIMCIKM_02901 0.0 chiA 3.2.1.14 GH18 G Glycoside Hydrolase Family 18
MIIMCIKM_02902 6.1e-137 K UTRA
MIIMCIKM_02903 1.1e-138 chbG 2.7.1.196, 2.7.1.205, 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
MIIMCIKM_02904 3e-51 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIIMCIKM_02905 6e-108 C nitroreductase
MIIMCIKM_02906 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MIIMCIKM_02909 2.6e-185 3.1.4.53 Q Calcineurin-like phosphoesterase
MIIMCIKM_02910 5.3e-101 CO Thioredoxin
MIIMCIKM_02911 2e-172 yeaC S COG0714 MoxR-like ATPases
MIIMCIKM_02912 5.9e-219 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MIIMCIKM_02913 0.0 yebA E COG1305 Transglutaminase-like enzymes
MIIMCIKM_02914 2.9e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MIIMCIKM_02915 4.1e-77 S glyoxalase bleomycin resistance protein dioxygenase
MIIMCIKM_02916 5.5e-240 C Na+/H+ antiporter family
MIIMCIKM_02917 2.3e-187 ord 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
MIIMCIKM_02918 1.2e-169 K LysR substrate binding domain
MIIMCIKM_02919 2.1e-210 S Erythromycin esterase
MIIMCIKM_02920 1.1e-84 K Bacterial regulatory proteins, tetR family
MIIMCIKM_02921 6.9e-116 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
MIIMCIKM_02922 6.6e-185 yxeA V FtsX-like permease family
MIIMCIKM_02923 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
MIIMCIKM_02924 1.5e-71 3.1.21.3 L Type I restriction modification DNA specificity domain
MIIMCIKM_02925 0.0 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
MIIMCIKM_02926 2.2e-123 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MIIMCIKM_02927 1.3e-54 arsR K transcriptional
MIIMCIKM_02928 5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MIIMCIKM_02931 1e-239 oxdD 4.1.1.2 G Oxalate decarboxylase
MIIMCIKM_02933 1.7e-167 catE 1.13.11.2 S glyoxalase
MIIMCIKM_02934 1.6e-117 ydhC K FCD
MIIMCIKM_02935 2.7e-199 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MIIMCIKM_02936 3.9e-65 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIIMCIKM_02937 7.8e-199 K ArsR family transcriptional regulator
MIIMCIKM_02938 4.9e-224 EGP Major facilitator Superfamily
MIIMCIKM_02939 2.6e-129 1.14.12.17 C Oxidoreductase NAD-binding domain
MIIMCIKM_02940 0.0 L ABC transporter
MIIMCIKM_02941 3.9e-74 yndB K Activator of Hsp90 ATPase homolog 1-like protein
MIIMCIKM_02942 3e-56 smtB K helix_turn_helix, Arsenical Resistance Operon Repressor
MIIMCIKM_02944 3.4e-64 frataxin S Domain of unknown function (DU1801)
MIIMCIKM_02945 2.7e-49 azlD E Branched-chain amino acid transport protein (AzlD)
MIIMCIKM_02946 2.7e-126 azlC E AzlC protein
MIIMCIKM_02947 1.5e-74 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIIMCIKM_02948 8.1e-72 phnB5 S 3-demethylubiquinone-9 3-methyltransferase
MIIMCIKM_02949 3.6e-235 3.1.3.41, 3.6.1.55 F Belongs to the Nudix hydrolase family
MIIMCIKM_02950 1.2e-67 2.3.1.128 J L-PSP family endoribonuclease
MIIMCIKM_02951 0.0 K transcriptional regulator, MtlR
MIIMCIKM_02952 4.7e-157 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MIIMCIKM_02953 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MIIMCIKM_02954 8.4e-167 aadK G Streptomycin adenylyltransferase
MIIMCIKM_02955 4.7e-99
MIIMCIKM_02957 1.2e-26
MIIMCIKM_02962 1.8e-215 yxlH EGP Major facilitator Superfamily
MIIMCIKM_02963 0.0 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MIIMCIKM_02964 8.1e-205 NT chemotaxis protein
MIIMCIKM_02965 1.3e-226 S Acetyltransferase
MIIMCIKM_02966 1.7e-254 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
MIIMCIKM_02967 5.3e-147 ycsE 3.1.3.104 S hydrolases of the HAD superfamily
MIIMCIKM_02968 3.2e-175 troA P Belongs to the bacterial solute-binding protein 9 family
MIIMCIKM_02969 3.2e-141 troB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MIIMCIKM_02970 2.2e-160 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MIIMCIKM_02971 2.3e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MIIMCIKM_02972 7.5e-100 S UPF0302 domain
MIIMCIKM_02973 6e-55 yflT S Heat induced stress protein YflT
MIIMCIKM_02974 2.6e-43 ydzA EGP Major facilitator Superfamily
MIIMCIKM_02975 1.5e-230 ywbD 2.1.1.191 J Methyltransferase
MIIMCIKM_02976 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MIIMCIKM_02977 4.3e-250 3.1.3.1 P Belongs to the alkaline phosphatase family
MIIMCIKM_02978 5.7e-120 ydbC G Domain of unknown function (DUF4937
MIIMCIKM_02979 2.3e-136 map 3.4.11.18 E Methionine aminopeptidase
MIIMCIKM_02980 1.5e-155 yuaG 3.4.21.72 S protein conserved in bacteria
MIIMCIKM_02981 1.7e-82 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MIIMCIKM_02983 1.3e-290 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MIIMCIKM_02984 1.9e-71 bdbC O Required for disulfide bond formation in some proteins
MIIMCIKM_02985 3.2e-75 bdbA CO Thioredoxin
MIIMCIKM_02986 4e-93 holA 2.7.7.7 L DNA polymerase III delta subunit
MIIMCIKM_02987 4.8e-36 rpsT J Binds directly to 16S ribosomal RNA
MIIMCIKM_02988 8.4e-207 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MIIMCIKM_02989 5.3e-204 spoIIP M stage II sporulation protein P
MIIMCIKM_02990 4.3e-53
MIIMCIKM_02991 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MIIMCIKM_02992 1.6e-221 hemN H Involved in the biosynthesis of porphyrin-containing compound
MIIMCIKM_02993 1.2e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MIIMCIKM_02994 1.4e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIIMCIKM_02995 9.9e-298 dnaK O Heat shock 70 kDa protein
MIIMCIKM_02996 4.3e-195 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MIIMCIKM_02997 9.3e-175 prmA J Methylates ribosomal protein L11
MIIMCIKM_02998 1.3e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MIIMCIKM_02999 3.8e-254 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MIIMCIKM_03000 9.6e-138 ycgJ_1 Q ubiE/COQ5 methyltransferase family
MIIMCIKM_03001 7.4e-220 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MIIMCIKM_03002 1.3e-114 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MIIMCIKM_03003 1.3e-176 iolS C Aldo keto reductase
MIIMCIKM_03004 6.4e-160 yqeW P COG1283 Na phosphate symporter
MIIMCIKM_03005 2.1e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MIIMCIKM_03006 9.4e-56 yqeY S Yqey-like protein
MIIMCIKM_03007 7.8e-223 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MIIMCIKM_03008 3.4e-98 yqfA S UPF0365 protein
MIIMCIKM_03009 1.6e-73
MIIMCIKM_03010 1.8e-47 yqfC S sporulation protein YqfC
MIIMCIKM_03011 1.2e-222 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MIIMCIKM_03012 6.8e-173 phoH T Phosphate starvation-inducible protein PhoH
MIIMCIKM_03013 1.6e-105 K Transcriptional regulator
MIIMCIKM_03014 0.0 ydfJ S MMPL family
MIIMCIKM_03015 9.8e-189 S domain protein
MIIMCIKM_03016 2.7e-185 oppF3 E Belongs to the ABC transporter superfamily
MIIMCIKM_03017 1.1e-181 oppD3 P Belongs to the ABC transporter superfamily
MIIMCIKM_03018 4.1e-167 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_03019 1.5e-172 appB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_03020 0.0 oppA5 E Bacterial extracellular solute-binding proteins, family 5 Middle
MIIMCIKM_03022 1.5e-133 Z012_10580 S Sulfite exporter TauE/SafE
MIIMCIKM_03025 4.6e-112 S ABC-2 family transporter protein
MIIMCIKM_03026 4.5e-152 V ABC transporter
MIIMCIKM_03027 1.4e-71 2.7.1.191 G PTS system fructose IIA component
MIIMCIKM_03028 2.6e-80 2.7.1.191 G PTS system mannose fructose sorbose family
MIIMCIKM_03029 4.6e-115 G PTS system sorbose-specific iic component
MIIMCIKM_03030 6.9e-137 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
MIIMCIKM_03031 8.8e-201 M SIS domain
MIIMCIKM_03032 0.0 pspF K PTS system fructose IIA component
MIIMCIKM_03033 2e-123 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
MIIMCIKM_03034 3.2e-210 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MIIMCIKM_03035 5e-74 siaT_3 G Tripartite ATP-independent periplasmic transporters, DctQ component
MIIMCIKM_03036 6.7e-184 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MIIMCIKM_03037 3.5e-191 1.1.1.14 E Dehydrogenase
MIIMCIKM_03038 5.3e-110 K FCD domain
MIIMCIKM_03039 1.4e-175 uox 1.7.3.3, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MIIMCIKM_03040 1e-59 pucM 3.5.2.17 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MIIMCIKM_03041 2e-253 S Membrane
MIIMCIKM_03042 6e-260 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MIIMCIKM_03043 2.3e-215 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
MIIMCIKM_03045 7.9e-145 yqjF S Uncharacterized conserved protein (COG2071)
MIIMCIKM_03046 9.5e-46 ycbP S Protein of unknown function (DUF2512)
MIIMCIKM_03047 3.5e-91 yvdQ S Protein of unknown function (DUF3231)
MIIMCIKM_03048 2.4e-231 S Putative esterase
MIIMCIKM_03050 0.0 otrA J Elongation factor G, domain IV
MIIMCIKM_03052 5.5e-102 4.2.1.46, 5.1.3.2 GM NAD dependent epimerase/dehydratase family
MIIMCIKM_03053 1e-139 S Alpha/beta hydrolase family
MIIMCIKM_03054 3e-95 2.3.1.59 K Acetyltransferase (GNAT) domain
MIIMCIKM_03055 2.8e-151 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MIIMCIKM_03056 2.6e-156 yobV9 K transcriptional regulator
MIIMCIKM_03057 1.2e-117 yoaZ 3.5.1.124 S DJ-1/PfpI family
MIIMCIKM_03059 6.1e-129 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
MIIMCIKM_03060 5.1e-139 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MIIMCIKM_03061 8e-185 P ABC transporter substrate-binding protein
MIIMCIKM_03062 1.6e-162 E Glyoxalase-like domain
MIIMCIKM_03063 4.8e-143 MA20_35565 4.1.3.30 G Phosphoenolpyruvate phosphomutase
MIIMCIKM_03064 8.1e-114 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MIIMCIKM_03065 9.9e-45 sdpR K transcriptional
MIIMCIKM_03066 2.4e-164 K LysR substrate binding domain
MIIMCIKM_03067 6.4e-122 mdmC 2.1.1.104 S O-methyltransferase
MIIMCIKM_03068 3.6e-266 alsT E Sodium alanine symporter
MIIMCIKM_03069 1.2e-246 G Bacterial extracellular solute-binding protein
MIIMCIKM_03070 0.0 E cell wall organization
MIIMCIKM_03072 1.4e-127 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
MIIMCIKM_03073 1.1e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_03074 1.2e-239 arlS T His Kinase A (phosphoacceptor) domain
MIIMCIKM_03075 1.5e-197 I Acyltransferase family
MIIMCIKM_03076 1.6e-154 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03077 4.2e-175 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03078 1.3e-251 G Bacterial extracellular solute-binding protein
MIIMCIKM_03079 1.8e-206 T helix_turn_helix, arabinose operon control protein
MIIMCIKM_03080 0.0 2.7.13.3 T Histidine kinase
MIIMCIKM_03081 1.8e-225 S Oxidoreductase family, NAD-binding Rossmann fold
MIIMCIKM_03082 6.2e-159 MA20_16875 G Xylose isomerase-like TIM barrel
MIIMCIKM_03083 2e-222 MA20_16880 EM Protein of unknown function (DUF993)
MIIMCIKM_03084 1.1e-230 MA20_16885 S Oxidoreductase family, NAD-binding Rossmann fold
MIIMCIKM_03085 7e-150 K AraC-like ligand binding domain
MIIMCIKM_03086 1.7e-227 iolF EGP Major facilitator Superfamily
MIIMCIKM_03087 6.1e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MIIMCIKM_03088 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MIIMCIKM_03089 1.6e-238 purD 6.3.4.13 F Belongs to the GARS family
MIIMCIKM_03090 1.1e-284 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MIIMCIKM_03091 8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MIIMCIKM_03092 1.9e-192 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MIIMCIKM_03093 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MIIMCIKM_03094 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIIMCIKM_03095 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIIMCIKM_03096 1.4e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIIMCIKM_03097 6.5e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MIIMCIKM_03098 9.3e-250 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MIIMCIKM_03099 6.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIIMCIKM_03100 3.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIIMCIKM_03101 1.8e-128 S CAAX protease self-immunity
MIIMCIKM_03102 5.6e-103 rimL 1.1.1.25 J Acetyltransferase (GNAT) domain
MIIMCIKM_03103 1.6e-122 S PFAM AIG2 family protein
MIIMCIKM_03104 3.1e-110
MIIMCIKM_03105 8.6e-68 S Calcium/calmodulin dependent protein kinase II association domain
MIIMCIKM_03106 1.1e-30 yebG S NETI protein
MIIMCIKM_03107 2.2e-20 repB L Initiator Replication protein
MIIMCIKM_03108 2.7e-261 tctA S Tripartite tricarboxylate transporter TctA family
MIIMCIKM_03109 9.1e-75 S Tripartite tricarboxylate transporter TctB family
MIIMCIKM_03110 7.6e-191 S Tripartite tricarboxylate transporter family receptor
MIIMCIKM_03111 3.6e-120 citT T response regulator
MIIMCIKM_03112 8.3e-293 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MIIMCIKM_03113 2.9e-31 yjcE P COG0025 NhaP-type Na H and K H antiporters
MIIMCIKM_03115 7.4e-269 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MIIMCIKM_03116 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MIIMCIKM_03118 1.1e-195 3.6.3.20 P Belongs to the ABC transporter superfamily
MIIMCIKM_03119 8.3e-148 ugpE P PFAM binding-protein-dependent transport systems inner membrane component
MIIMCIKM_03120 1.3e-165 G ABC transporter (permease)
MIIMCIKM_03121 2.9e-153 G Xylose isomerase-like TIM barrel
MIIMCIKM_03122 1.3e-251 G Glycerol-3-phosphate ABC transporter substrate-binding protein
MIIMCIKM_03123 6.1e-75 ectC 4.2.1.108 S Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
MIIMCIKM_03124 2.3e-248 ectB 2.6.1.76 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MIIMCIKM_03125 4.1e-89 ectA 2.3.1.178 K L-2,4-diaminobutyric acid acetyltransferase
MIIMCIKM_03126 1.3e-53
MIIMCIKM_03127 1.8e-270 EG Bacillus/Clostridium GerA spore germination protein
MIIMCIKM_03128 1.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIIMCIKM_03129 7.8e-208 eutG C alcohol dehydrogenase
MIIMCIKM_03130 2.4e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
MIIMCIKM_03131 3.3e-234 EG COG2610 H gluconate symporter and related permeases
MIIMCIKM_03132 7e-220 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
MIIMCIKM_03133 0.0 KT Transcriptional regulator
MIIMCIKM_03134 4.5e-20
MIIMCIKM_03135 4.8e-54 fdx5 C 2Fe-2S iron-sulfur cluster binding domain
MIIMCIKM_03136 6.7e-98 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MIIMCIKM_03137 1.4e-34
MIIMCIKM_03138 4e-144 pdaB 3.5.1.104 G Polysaccharide deacetylase
MIIMCIKM_03139 4.1e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MIIMCIKM_03140 1.5e-58 gerD S Spore gernimation protein
MIIMCIKM_03141 1.7e-102
MIIMCIKM_03142 1.1e-175
MIIMCIKM_03143 3.9e-101 S Sporulation delaying protein SdpA
MIIMCIKM_03144 7.1e-77 S Bacterial PH domain
MIIMCIKM_03145 4.1e-195 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MIIMCIKM_03146 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIIMCIKM_03147 1.7e-151 glcT K antiterminator
MIIMCIKM_03148 8.9e-133 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MIIMCIKM_03149 1.4e-80 ybaK S Protein of unknown function (DUF2521)
MIIMCIKM_03152 6.6e-14
MIIMCIKM_03153 2.1e-115 S Rubrerythrin
MIIMCIKM_03156 1.9e-30 yozG K Transcriptional regulator
MIIMCIKM_03157 8.9e-82 S Protein of unknown function (DUF2975)
MIIMCIKM_03158 1.7e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
MIIMCIKM_03159 4.4e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MIIMCIKM_03160 1.1e-147 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MIIMCIKM_03161 1.2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MIIMCIKM_03162 6.9e-153 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MIIMCIKM_03163 8.4e-162 ecfA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MIIMCIKM_03164 9.4e-59 rplQ J Ribosomal protein L17
MIIMCIKM_03165 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIIMCIKM_03166 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MIIMCIKM_03167 1.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MIIMCIKM_03168 1.4e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MIIMCIKM_03169 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIIMCIKM_03170 1.4e-141 map 3.4.11.18 E Methionine aminopeptidase
MIIMCIKM_03171 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MIIMCIKM_03172 2.2e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MIIMCIKM_03173 3.3e-74 rplO J binds to the 23S rRNA
MIIMCIKM_03174 2.7e-25 rpmD J Ribosomal protein L30
MIIMCIKM_03175 4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MIIMCIKM_03176 1.3e-60 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIIMCIKM_03177 1.3e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MIIMCIKM_03178 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MIIMCIKM_03179 2.3e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MIIMCIKM_03180 6.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MIIMCIKM_03181 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MIIMCIKM_03182 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIIMCIKM_03183 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
MIIMCIKM_03184 4.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIIMCIKM_03185 8.7e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIIMCIKM_03186 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MIIMCIKM_03187 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MIIMCIKM_03188 1.7e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MIIMCIKM_03189 1.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MIIMCIKM_03190 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
MIIMCIKM_03191 1.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MIIMCIKM_03192 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MIIMCIKM_03193 6.6e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIIMCIKM_03194 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIIMCIKM_03195 3.5e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MIIMCIKM_03196 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIIMCIKM_03197 1e-35 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
MIIMCIKM_03198 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIIMCIKM_03199 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIIMCIKM_03200 1.3e-122 rsmC 2.1.1.172 J Methyltransferase
MIIMCIKM_03201 3.2e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MIIMCIKM_03202 3.5e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIIMCIKM_03203 9.4e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MIIMCIKM_03204 6.3e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIIMCIKM_03205 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
MIIMCIKM_03206 6.1e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MIIMCIKM_03207 5.6e-118 sigH K Belongs to the sigma-70 factor family
MIIMCIKM_03208 3e-87 yacP S RNA-binding protein containing a PIN domain
MIIMCIKM_03209 4.9e-145 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIIMCIKM_03210 5.1e-69 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MIIMCIKM_03211 2.5e-269 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MIIMCIKM_03212 2.5e-121 cysE 2.3.1.30 E Serine acetyltransferase
MIIMCIKM_03213 1.8e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIIMCIKM_03214 8.6e-84 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MIIMCIKM_03215 7.6e-118 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MIIMCIKM_03216 1.4e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MIIMCIKM_03217 2.7e-194 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MIIMCIKM_03218 2.1e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MIIMCIKM_03219 0.0 clpC O Belongs to the ClpA ClpB family
MIIMCIKM_03220 1.1e-195 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MIIMCIKM_03221 2.3e-95 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MIIMCIKM_03222 1.5e-72 ctsR K Belongs to the CtsR family
MIIMCIKM_03223 1.2e-285 G Bacterial extracellular solute-binding protein
MIIMCIKM_03224 7.4e-214 yceL EGP Major Facilitator Superfamily
MIIMCIKM_03225 8.3e-142 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MIIMCIKM_03226 1.8e-232 ugpB G Glycerol-3-phosphate ABC transporter substrate-binding protein
MIIMCIKM_03227 6.2e-143 ugpE P Glycerol-3-phosphate ABC transporter permease
MIIMCIKM_03228 1e-165 ugpA G ABC transporter (permease)
MIIMCIKM_03229 3.5e-205 ugpC 3.6.3.20 P Belongs to the ABC transporter superfamily
MIIMCIKM_03230 0.0 glpQ1 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MIIMCIKM_03231 2e-241 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIIMCIKM_03232 1.2e-76 nsrR K Transcriptional regulator
MIIMCIKM_03233 2.1e-196 araC2 K Arabinose-binding domain of AraC transcription regulator, N-term
MIIMCIKM_03234 4.2e-144 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIIMCIKM_03236 3.9e-45
MIIMCIKM_03237 2.4e-237 S LXG domain of WXG superfamily
MIIMCIKM_03238 2.8e-36 S Family of unknown function (DUF5344)
MIIMCIKM_03240 1.9e-33 S response regulator aspartate phosphatase
MIIMCIKM_03241 1.2e-163 vraB 2.3.1.9 I Belongs to the thiolase family
MIIMCIKM_03242 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MIIMCIKM_03243 8.4e-93 bofC S BofC C-terminal domain
MIIMCIKM_03244 2.9e-63 1.9.3.1 C cytochrome c oxidase subunit II
MIIMCIKM_03245 5.6e-22 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIIMCIKM_03246 7.7e-121 safA M spore coat assembly protein SafA
MIIMCIKM_03247 5.2e-25 safA M spore coat assembly protein SafA
MIIMCIKM_03248 3.6e-210 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MIIMCIKM_03249 7.1e-150 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MIIMCIKM_03250 3.1e-289 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MIIMCIKM_03251 4.4e-208 nifS 2.8.1.7 E Cysteine desulfurase
MIIMCIKM_03252 1.5e-90 niaR S small molecule binding protein (contains 3H domain)
MIIMCIKM_03253 1.3e-162 pheA 4.2.1.51 E Prephenate dehydratase
MIIMCIKM_03254 1.8e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
MIIMCIKM_03255 1.1e-223 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MIIMCIKM_03256 1.8e-101 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MIIMCIKM_03258 1.1e-264 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MIIMCIKM_03259 1.3e-181 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MIIMCIKM_03260 2.1e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MIIMCIKM_03261 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MIIMCIKM_03262 1.1e-122 ccdA O cytochrome c biogenesis protein
MIIMCIKM_03263 9.9e-129 ecsC S EcsC protein family
MIIMCIKM_03264 3.1e-215 ecsB U ABC transporter
MIIMCIKM_03265 1.3e-51 ecsA V transporter (ATP-binding protein)
MIIMCIKM_03266 1.2e-269 ydbT S Bacterial PH domain
MIIMCIKM_03267 1.9e-86 S Bacterial PH domain
MIIMCIKM_03268 1.1e-139 S CAAX protease self-immunity
MIIMCIKM_03269 6.5e-251 celF 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MIIMCIKM_03270 1.7e-45
MIIMCIKM_03271 6.5e-224 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MIIMCIKM_03272 4.7e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MIIMCIKM_03273 8.8e-51 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MIIMCIKM_03274 7.1e-211 ybhE S Bacterial protein of unknown function (DUF871)
MIIMCIKM_03275 7.5e-161 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
MIIMCIKM_03276 5.6e-166 K Transcriptional regulator
MIIMCIKM_03278 1.4e-292 E Bacterial extracellular solute-binding proteins, family 5 Middle
MIIMCIKM_03279 1e-157 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03280 4.1e-167 EP N-terminal TM domain of oligopeptide transport permease C
MIIMCIKM_03281 5.5e-186 oppD P Belongs to the ABC transporter superfamily
MIIMCIKM_03282 5.2e-195 E Belongs to the ABC transporter superfamily
MIIMCIKM_03283 1.5e-225 E Peptidase family M28
MIIMCIKM_03284 2.9e-241 P Sodium:sulfate symporter transmembrane region
MIIMCIKM_03285 1.9e-225 3.5.1.47 S Peptidase dimerisation domain
MIIMCIKM_03286 2.7e-227 3.5.1.47 S Peptidase dimerisation domain
MIIMCIKM_03287 1.4e-75 lytE M NlpC/P60 family
MIIMCIKM_03288 3.6e-132 lytE M NlpC/P60 family
MIIMCIKM_03289 1.5e-241 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIIMCIKM_03290 1.4e-231
MIIMCIKM_03291 9e-46 HA62_12640 S GCN5-related N-acetyl-transferase
MIIMCIKM_03292 6.9e-167 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MIIMCIKM_03293 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MIIMCIKM_03294 2.8e-227 rodA D Belongs to the SEDS family
MIIMCIKM_03295 3.8e-78 FG Scavenger mRNA decapping enzyme C-term binding
MIIMCIKM_03296 2.4e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MIIMCIKM_03297 3.3e-83 S Tetratrico peptide repeat
MIIMCIKM_03298 1.6e-171 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MIIMCIKM_03299 1.1e-116 ywqC M biosynthesis protein
MIIMCIKM_03300 2.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MIIMCIKM_03301 4.2e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MIIMCIKM_03302 1.9e-72 S An automated process has identified a potential problem with this gene model
MIIMCIKM_03303 4.5e-130 S Protein of unknown function (DUF3100)
MIIMCIKM_03304 1e-156 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MIIMCIKM_03305 4.3e-272 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIIMCIKM_03306 4.1e-289 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 T Domain present in phytochromes and cGMP-specific phosphodiesterases.
MIIMCIKM_03307 1.6e-165 S Tetratricopeptide repeat
MIIMCIKM_03310 1.9e-110 glnP E Polar amino acid ABC transporter, inner membrane subunit
MIIMCIKM_03311 1.1e-144 glnH ET Ligated ion channel L-glutamate- and glycine-binding site
MIIMCIKM_03312 1.2e-63 S Bacterial PH domain
MIIMCIKM_03313 5.8e-269 gabD_2 1.2.1.9 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIIMCIKM_03314 7.7e-194 hom2 1.1.1.3 E Homoserine dehydrogenase
MIIMCIKM_03315 2.7e-227 amaA 3.5.1.47 E Peptidase dimerisation domain
MIIMCIKM_03316 2.4e-228 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
MIIMCIKM_03317 1.2e-235 eutD 3.4.13.9, 3.5.4.44 E Creatinase/Prolidase N-terminal domain
MIIMCIKM_03318 5.4e-251 nhaC C Na H antiporter
MIIMCIKM_03320 3.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MIIMCIKM_03321 2.2e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MIIMCIKM_03322 0.0 QT COG2508 Regulator of polyketide synthase expression
MIIMCIKM_03323 7.4e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MIIMCIKM_03324 9.2e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MIIMCIKM_03325 1.5e-239 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MIIMCIKM_03326 3.3e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MIIMCIKM_03327 3.6e-150 yaaC S YaaC-like Protein
MIIMCIKM_03329 4.2e-64
MIIMCIKM_03331 0.0 2.7.13.3 T Histidine kinase
MIIMCIKM_03333 5.7e-200 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIIMCIKM_03334 2.6e-140 S GNAT acetyltransferase
MIIMCIKM_03335 3.9e-69
MIIMCIKM_03336 4.1e-68
MIIMCIKM_03337 0.0
MIIMCIKM_03338 4e-124
MIIMCIKM_03339 1.2e-88
MIIMCIKM_03340 5.2e-75 yosT L Bacterial transcription activator, effector binding domain
MIIMCIKM_03341 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIIMCIKM_03342 1.9e-89 K GrpB protein
MIIMCIKM_03343 4.8e-176 O Predicted Zn-dependent protease (DUF2268)
MIIMCIKM_03344 2e-143 mta K TipAS antibiotic-recognition domain
MIIMCIKM_03346 1.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MIIMCIKM_03347 1e-111 yrbG3 S membrane
MIIMCIKM_03348 2.2e-108 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIIMCIKM_03349 3.5e-174 murB 1.3.1.98 M cell wall formation
MIIMCIKM_03350 3.9e-173
MIIMCIKM_03351 2.5e-53
MIIMCIKM_03352 4.5e-177 S Choline/ethanolamine kinase
MIIMCIKM_03353 2.2e-90 ykuD S protein conserved in bacteria
MIIMCIKM_03354 5.6e-225 S Erythromycin esterase
MIIMCIKM_03355 2.9e-169 NT chemotaxis protein
MIIMCIKM_03356 2.1e-137 IQ Enoyl-(Acyl carrier protein) reductase
MIIMCIKM_03357 4.4e-256 putP E Sodium:solute symporter family
MIIMCIKM_03358 7.4e-191 3.5.3.6 E Amidinotransferase
MIIMCIKM_03359 1.7e-184 K Transcriptional regulator
MIIMCIKM_03360 2.2e-154 V ABC transporter
MIIMCIKM_03361 1.3e-111 S ABC-2 family transporter protein
MIIMCIKM_03362 1.3e-148 K Transcriptional regulator
MIIMCIKM_03363 9.2e-153 yxxF EG EamA-like transporter family
MIIMCIKM_03364 1.2e-100
MIIMCIKM_03365 0.0
MIIMCIKM_03366 2.9e-276
MIIMCIKM_03368 3.2e-158 proX E Substrate binding domain of ABC-type glycine betaine transport system
MIIMCIKM_03369 2e-100 K Belongs to the GbsR family
MIIMCIKM_03370 5.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MIIMCIKM_03371 5.4e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
MIIMCIKM_03372 1.2e-138 yvfI K COG2186 Transcriptional regulators
MIIMCIKM_03373 2.6e-126 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MIIMCIKM_03374 9.2e-275 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MIIMCIKM_03375 5.9e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MIIMCIKM_03376 0.0 lldP C L-lactate permease
MIIMCIKM_03377 4.8e-15
MIIMCIKM_03378 5.8e-230 cypA C Cytochrome P450
MIIMCIKM_03379 3.4e-275 ydaH H AbgT putative transporter family
MIIMCIKM_03380 0.0 htpG O Molecular chaperone. Has ATPase activity
MIIMCIKM_03381 2.1e-102 yaaI Q Isochorismatase family
MIIMCIKM_03382 7e-75 ygaO
MIIMCIKM_03383 5.4e-27 K Transcriptional regulator
MIIMCIKM_03384 0.0 sasH 3.1.3.5, 3.6.1.45 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MIIMCIKM_03385 4.4e-121 radC E Belongs to the UPF0758 family
MIIMCIKM_03386 2.4e-104 maf D septum formation protein Maf
MIIMCIKM_03387 0.0 yuxL 3.4.19.1 EU peptidase
MIIMCIKM_03388 9.1e-198
MIIMCIKM_03389 7.7e-121 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MIIMCIKM_03390 3.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MIIMCIKM_03391 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MIIMCIKM_03392 4.9e-31
MIIMCIKM_03393 4.3e-106
MIIMCIKM_03394 1.5e-191 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MIIMCIKM_03395 1.2e-165
MIIMCIKM_03396 2.2e-162 spoVID M stage VI sporulation protein D
MIIMCIKM_03397 1.1e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MIIMCIKM_03398 3.7e-182 hemB 4.2.1.24 H Belongs to the ALAD family
MIIMCIKM_03399 8.6e-139 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MIIMCIKM_03400 3.4e-169 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MIIMCIKM_03401 2.4e-147 hemX O cytochrome C
MIIMCIKM_03402 1.4e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MIIMCIKM_03403 6.3e-66 engB D Necessary for normal cell division and for the maintenance of normal septation
MIIMCIKM_03404 7.7e-184 gerM S COG5401 Spore germination protein
MIIMCIKM_03405 8e-137 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MIIMCIKM_03406 1.6e-108 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIIMCIKM_03407 9.4e-97 ysnB S Phosphoesterase
MIIMCIKM_03410 3.3e-307 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MIIMCIKM_03411 8.1e-274 M Glycosyl transferase family group 2
MIIMCIKM_03412 3.1e-74
MIIMCIKM_03413 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MIIMCIKM_03414 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MIIMCIKM_03415 1.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
MIIMCIKM_03416 1.2e-178 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIIMCIKM_03417 1.4e-284 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIIMCIKM_03418 5.3e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MIIMCIKM_03419 6.1e-271 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIIMCIKM_03420 9.2e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIIMCIKM_03421 2.2e-196 trxA2 O COG0457 FOG TPR repeat
MIIMCIKM_03422 3.9e-232 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MIIMCIKM_03423 1.7e-273 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MIIMCIKM_03424 6.9e-209 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MIIMCIKM_03426 1.7e-196 S Psort location CytoplasmicMembrane, score
MIIMCIKM_03427 1.1e-161 ccpC K Transcriptional regulator
MIIMCIKM_03428 1.4e-80 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MIIMCIKM_03429 8e-257 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MIIMCIKM_03430 4.8e-271 spoVAF EG Stage V sporulation protein AF
MIIMCIKM_03431 2.6e-106 spoVAEA S Stage V sporulation protein AE
MIIMCIKM_03432 5.1e-57 spoVAEB S Pfam:SpoVA
MIIMCIKM_03433 4e-184 spoVAD I Stage V sporulation protein AD
MIIMCIKM_03434 2.2e-79 S Pfam:SpoVA
MIIMCIKM_03435 4.8e-137 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIIMCIKM_03436 4.3e-74 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MIIMCIKM_03437 3.9e-54 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MIIMCIKM_03438 1.3e-215 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MIIMCIKM_03439 5.8e-143 3.5.1.104 G Polysaccharide deacetylase
MIIMCIKM_03440 2.5e-83 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MIIMCIKM_03441 3.3e-56
MIIMCIKM_03442 2.8e-20 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MIIMCIKM_03443 1.2e-242 emrB_1 EGP Major facilitator Superfamily
MIIMCIKM_03444 2.5e-120 yocB J translation release factor activity
MIIMCIKM_03445 1.8e-69 ohrB O Organic hydroperoxide resistance protein
MIIMCIKM_03446 1e-235 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MIIMCIKM_03447 5.9e-227 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MIIMCIKM_03448 1.9e-169 xerD L recombinase XerD
MIIMCIKM_03449 9.6e-14 S Protein of unknown function (DUF4227)
MIIMCIKM_03450 5e-87 fur P Belongs to the Fur family
MIIMCIKM_03451 5.5e-102 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MIIMCIKM_03452 1.8e-93 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MIIMCIKM_03454 1.2e-88 CO Thioredoxin-like
MIIMCIKM_03455 1.8e-142 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MIIMCIKM_03456 3.9e-212 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MIIMCIKM_03457 6.9e-93 S UPF0316 protein
MIIMCIKM_03458 7.8e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MIIMCIKM_03459 7e-98 yvbF K Belongs to the GbsR family
MIIMCIKM_03460 6e-54 ybaZ 2.1.1.63 L Methyltransferase
MIIMCIKM_03461 2.9e-84 V COG4767 Glycopeptide antibiotics resistance protein
MIIMCIKM_03462 3.3e-188 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MIIMCIKM_03463 0.0 asnO 6.3.5.4 E Asparagine synthase
MIIMCIKM_03464 1.3e-207 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIIMCIKM_03465 4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIIMCIKM_03466 1.1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MIIMCIKM_03467 3.3e-125 P Polycystin cation channel
MIIMCIKM_03468 1.1e-248 lysC 2.7.2.4 E Belongs to the aspartokinase family
MIIMCIKM_03470 2.5e-49
MIIMCIKM_03471 3.4e-46 tnrA K transcriptional
MIIMCIKM_03472 3.3e-149 yibQ S protein conserved in bacteria
MIIMCIKM_03473 0.0 apr O Belongs to the peptidase S8 family
MIIMCIKM_03474 5.5e-42
MIIMCIKM_03475 2e-74 ykuL S CBS domain
MIIMCIKM_03476 4.5e-82 3.6.1.55 S Pfam Polyketide cyclase dehydrase and lipid transport
MIIMCIKM_03477 2.2e-70 yaaR S protein conserved in bacteria
MIIMCIKM_03480 2e-200 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MIIMCIKM_03481 2e-73 5.1.99.1 E COG0346 Lactoylglutathione lyase and related lyases
MIIMCIKM_03483 1.2e-94 yqjB S protein conserved in bacteria
MIIMCIKM_03484 8.5e-171 yqjA S Putative aromatic acid exporter C-terminal domain
MIIMCIKM_03485 2.4e-178 pilS 2.7.13.3 F GHKL domain
MIIMCIKM_03486 1.9e-92 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIIMCIKM_03487 3.1e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MIIMCIKM_03488 2.3e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MIIMCIKM_03489 7.4e-30 K Cro/C1-type HTH DNA-binding domain
MIIMCIKM_03490 1.8e-50 ansR K Helix-turn-helix XRE-family like proteins
MIIMCIKM_03491 1.7e-30
MIIMCIKM_03492 4.9e-139 yjcH P COG2382 Enterochelin esterase and related enzymes
MIIMCIKM_03493 8.9e-95 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MIIMCIKM_03494 5.1e-78 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MIIMCIKM_03495 1.1e-195 dglA S Thiamine-binding protein
MIIMCIKM_03496 4.2e-98
MIIMCIKM_03497 1.1e-142 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MIIMCIKM_03498 2.9e-212 thiO 1.4.3.19 E Glycine oxidase
MIIMCIKM_03499 4.8e-140 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MIIMCIKM_03500 4e-27 thiS H ThiS family
MIIMCIKM_03501 2e-109 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MIIMCIKM_03502 2.5e-264 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MIIMCIKM_03503 2.4e-181 glcK 2.7.1.2 G Glucokinase
MIIMCIKM_03504 3.4e-132 IQ Short-chain dehydrogenase reductase sdr
MIIMCIKM_03505 6.7e-81 S Bacterial PH domain
MIIMCIKM_03506 1.5e-101 K Bacterial regulatory proteins, tetR family
MIIMCIKM_03507 2.6e-202 C NADH:flavin oxidoreductase / NADH oxidase family
MIIMCIKM_03508 1.9e-248 gerAA EG Spore germination protein
MIIMCIKM_03509 1.5e-192 gerAB E Spore germination protein
MIIMCIKM_03510 1.8e-212 gerAC S Spore germination B3/ GerAC like, C-terminal
MIIMCIKM_03511 3.7e-199 S response regulator aspartate phosphatase
MIIMCIKM_03514 1.4e-148 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MIIMCIKM_03515 1.5e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MIIMCIKM_03516 3.1e-87 cpsE M Bacterial sugar transferase
MIIMCIKM_03517 8e-41 wzx S Polysaccharide biosynthesis protein
MIIMCIKM_03518 5.3e-23 S Glycosyl transferase family 2
MIIMCIKM_03520 7.1e-37 GT2 V Glycosyl transferase, family 2
MIIMCIKM_03521 1e-122 wcoF M Glycosyltransferase Family 4
MIIMCIKM_03522 3.4e-57 M Psort location CytoplasmicMembrane, score 7.88
MIIMCIKM_03523 1e-138 rgpAc GT4 M Domain of unknown function (DUF1972)
MIIMCIKM_03524 3.6e-168 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MIIMCIKM_03525 1.3e-153 yidA S hydrolases of the HAD superfamily
MIIMCIKM_03526 9.9e-91 S DinB family
MIIMCIKM_03527 1.4e-167 K WYL domain
MIIMCIKM_03528 3.3e-103 S Bacteriocin-protection, YdeI or OmpD-Associated
MIIMCIKM_03529 2.6e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MIIMCIKM_03530 6.4e-190 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MIIMCIKM_03532 2.1e-117 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIIMCIKM_03533 1.6e-210 yhcY 2.7.13.3 T Histidine kinase
MIIMCIKM_03534 1.9e-39
MIIMCIKM_03535 1.1e-11 KLT serine threonine protein kinase
MIIMCIKM_03536 4.1e-118 KLT serine threonine protein kinase
MIIMCIKM_03537 5.7e-86 K Transcriptional regulator
MIIMCIKM_03538 2.3e-141 3.1.26.11 S Metallo-beta-lactamase superfamily
MIIMCIKM_03539 2.1e-109 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MIIMCIKM_03540 5.4e-10
MIIMCIKM_03541 2.9e-140
MIIMCIKM_03542 2.1e-123 yhcG V ABC transporter, ATP-binding protein
MIIMCIKM_03543 8.6e-63 K helix_turn_helix gluconate operon transcriptional repressor
MIIMCIKM_03545 1.7e-135
MIIMCIKM_03546 1.3e-159 S NYN domain
MIIMCIKM_03547 1.6e-52 K sequence-specific DNA binding
MIIMCIKM_03548 3.4e-299 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MIIMCIKM_03549 6.2e-257 G Bacterial extracellular solute-binding protein
MIIMCIKM_03550 1.3e-139 P Bacterial extracellular solute-binding protein
MIIMCIKM_03551 6.7e-201 fbpC2 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MIIMCIKM_03552 4.3e-292 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03553 9.5e-308 2.7.13.3 T Histidine kinase
MIIMCIKM_03554 8.6e-139 T helix_turn_helix, arabinose operon control protein
MIIMCIKM_03555 1.1e-203 S response regulator aspartate phosphatase
MIIMCIKM_03556 4.5e-129 puuD 4.1.3.27 S Peptidase C26
MIIMCIKM_03557 5.8e-155 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIIMCIKM_03558 1.5e-192 T PhoQ Sensor
MIIMCIKM_03559 1.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_03560 1.6e-166 V ABC transporter, ATP-binding protein
MIIMCIKM_03561 5.2e-122 S ABC-2 family transporter protein
MIIMCIKM_03562 2.8e-93 S Putative adhesin
MIIMCIKM_03563 1.3e-34
MIIMCIKM_03565 1.3e-73
MIIMCIKM_03566 1.4e-30 S response regulator aspartate phosphatase
MIIMCIKM_03567 2.3e-207 S Protein of unknown function (DUF418)
MIIMCIKM_03568 1.3e-154 K Transcriptional regulator
MIIMCIKM_03569 8e-165 S Belongs to the pirin family
MIIMCIKM_03570 3.1e-59 hxlR K HxlR-like helix-turn-helix
MIIMCIKM_03571 1.4e-248 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
MIIMCIKM_03572 2.6e-133 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MIIMCIKM_03573 3.4e-255 3.5.4.28, 3.5.4.31 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
MIIMCIKM_03574 3.2e-237 S protein conserved in bacteria
MIIMCIKM_03575 1.6e-182 S COG1073 Hydrolases of the alpha beta superfamily
MIIMCIKM_03577 5.9e-94
MIIMCIKM_03578 4.8e-99 S Histidine kinase
MIIMCIKM_03579 1.1e-183 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MIIMCIKM_03580 1.2e-57 FG HIT domain
MIIMCIKM_03581 5.5e-166 KLT Protein kinase domain
MIIMCIKM_03582 1.2e-80 S Stage II sporulation protein P (SpoIIP)
MIIMCIKM_03583 7.6e-144 K acetyltransferase
MIIMCIKM_03584 1.1e-104 K Bacterial regulatory proteins, tetR family
MIIMCIKM_03585 6e-217 codB_1 F cytosine purines uracil thiamine allantoin
MIIMCIKM_03586 1.4e-206 S Protein of unknown function (DUF917)
MIIMCIKM_03587 2.1e-288 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
MIIMCIKM_03588 1.4e-27
MIIMCIKM_03589 4.2e-118 ypgQ S phosphohydrolase
MIIMCIKM_03590 4.1e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
MIIMCIKM_03591 7.2e-95 S Peptidase M50
MIIMCIKM_03592 1e-35 S membrane
MIIMCIKM_03594 2.5e-142 rrmA 2.1.1.187 Q Methyltransferase domain
MIIMCIKM_03595 7.7e-91 M FR47-like protein
MIIMCIKM_03596 1.1e-59 ydcN K Helix-turn-helix XRE-family like proteins
MIIMCIKM_03597 1.7e-237 hyuA 3.5.2.2 F Amidohydrolase family
MIIMCIKM_03598 2.6e-07
MIIMCIKM_03599 1.7e-237 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MIIMCIKM_03600 1.1e-261 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MIIMCIKM_03601 4e-77 F PFAM AIG2 family protein
MIIMCIKM_03602 7.4e-115 ywnB S NAD(P)H-binding
MIIMCIKM_03603 5.7e-71 ywnA K Transcriptional regulator
MIIMCIKM_03605 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIIMCIKM_03606 6e-67 licT K transcriptional antiterminator
MIIMCIKM_03607 1.5e-70 licT K transcriptional antiterminator
MIIMCIKM_03608 2.5e-288 bglH7 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MIIMCIKM_03609 3.2e-56 L Transposase and inactivated derivatives
MIIMCIKM_03610 2.1e-68 L transposase activity
MIIMCIKM_03611 4e-53
MIIMCIKM_03612 2.9e-75 S Protein of unknown function, DUF600
MIIMCIKM_03613 1.8e-80 S SMI1-KNR4 cell-wall
MIIMCIKM_03614 8.2e-37
MIIMCIKM_03615 1.6e-93
MIIMCIKM_03616 7.5e-76 S Immunity protein 70
MIIMCIKM_03617 3.3e-119 U Belongs to the WXG100 family
MIIMCIKM_03618 5.8e-61
MIIMCIKM_03619 6.2e-54
MIIMCIKM_03620 0.0 M nuclease activity
MIIMCIKM_03621 4.6e-39 S Family of unknown function (DUF5344)
MIIMCIKM_03622 1e-47 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MIIMCIKM_03623 2e-194 echA9 1.1.1.31, 3.1.2.4, 4.2.1.17 I 3-hydroxyisobutyryl-CoA hydrolase
MIIMCIKM_03624 2e-112 ribE 2.5.1.9 H Riboflavin synthase
MIIMCIKM_03625 3e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MIIMCIKM_03626 1.6e-82 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MIIMCIKM_03627 2.6e-85 ypuF S Domain of unknown function (DUF309)
MIIMCIKM_03628 2.2e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MIIMCIKM_03629 1.6e-97 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIIMCIKM_03630 8e-105 K Uncharacterized protein conserved in bacteria (DUF2087)
MIIMCIKM_03631 2.7e-296 aldA C Belongs to the aldehyde dehydrogenase family
MIIMCIKM_03632 1.4e-169 sodA 1.15.1.1 P Superoxide dismutase
MIIMCIKM_03633 2.6e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIIMCIKM_03634 1.1e-308 ubiB S ABC1 family
MIIMCIKM_03635 6.8e-45 S ATP synthase, subunit b
MIIMCIKM_03636 4.2e-124 S membrane
MIIMCIKM_03637 7.1e-45 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MIIMCIKM_03638 8.1e-79 spoVAC S stage V sporulation protein AC
MIIMCIKM_03639 1.1e-192 spoVAD I Stage V sporulation protein AD
MIIMCIKM_03640 1.2e-55 spoVAE S stage V sporulation protein
MIIMCIKM_03641 5.5e-214 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MIIMCIKM_03642 1.9e-101 spmA S Spore maturation protein
MIIMCIKM_03643 1.4e-74 spmB S Spore maturation protein
MIIMCIKM_03644 3.7e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MIIMCIKM_03645 3.4e-97 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MIIMCIKM_03646 2.9e-284 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MIIMCIKM_03647 2.4e-66 yshE S membrane
MIIMCIKM_03648 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MIIMCIKM_03649 4.6e-103 fadR K Transcriptional regulator
MIIMCIKM_03650 4.4e-138 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MIIMCIKM_03651 1.1e-133 etfB C Electron transfer flavoprotein
MIIMCIKM_03652 1.1e-175 etfA C Electron transfer flavoprotein
MIIMCIKM_03653 1.8e-53 trxA O Belongs to the thioredoxin family
MIIMCIKM_03654 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MIIMCIKM_03655 1.3e-75 yslB S Protein of unknown function (DUF2507)
MIIMCIKM_03656 7.2e-229 ktrB P COG0168 Trk-type K transport systems, membrane components
MIIMCIKM_03657 2.7e-111 sdhC C succinate dehydrogenase
MIIMCIKM_03658 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MIIMCIKM_03659 9.5e-146 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MIIMCIKM_03660 2.5e-80 fcbC S thioesterase
MIIMCIKM_03661 1.6e-32 gerE K Transcriptional regulator
MIIMCIKM_03662 1.3e-38 ptsH G phosphocarrier protein HPr
MIIMCIKM_03663 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIIMCIKM_03664 1.9e-80 ysmB 2.4.2.28 K transcriptional
MIIMCIKM_03665 2.4e-150 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MIIMCIKM_03666 1.5e-106 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MIIMCIKM_03667 4e-36 K COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit
MIIMCIKM_03668 5.6e-113 S Golgi phosphoprotein 3 (GPP34)
MIIMCIKM_03669 1.7e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MIIMCIKM_03670 5.8e-141 motA N flagellar motor
MIIMCIKM_03671 2e-135 motB N Flagellar motor protein
MIIMCIKM_03672 7.4e-203 ytvI S sporulation integral membrane protein YtvI
MIIMCIKM_03673 9.1e-87 dksA T general stress protein
MIIMCIKM_03674 4.1e-59 S Uncharacterized protein conserved in bacteria (DUF2200)
MIIMCIKM_03675 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MIIMCIKM_03676 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MIIMCIKM_03677 7.8e-70 yccU S CoA-binding protein
MIIMCIKM_03678 1.4e-287 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
MIIMCIKM_03679 5.4e-192 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MIIMCIKM_03680 8.1e-148 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_03681 2.8e-100 IV02_12955 U MarC family integral membrane protein
MIIMCIKM_03682 2.7e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MIIMCIKM_03683 4.3e-52 S Belongs to the HesB IscA family
MIIMCIKM_03684 2.5e-95 Q ubiE/COQ5 methyltransferase family
MIIMCIKM_03685 1.9e-84 G Transmembrane secretion effector
MIIMCIKM_03686 9.3e-153 yjcE P COG0025 NhaP-type Na H and K H antiporters
MIIMCIKM_03687 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIIMCIKM_03688 4.9e-310 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIIMCIKM_03690 3.8e-235 G Major facilitator Superfamily
MIIMCIKM_03691 1.2e-21
MIIMCIKM_03693 2e-97 ypbQ S protein conserved in bacteria
MIIMCIKM_03694 9.4e-211 bcsA Q Naringenin-chalcone synthase
MIIMCIKM_03695 8.1e-129 mta K transcriptional
MIIMCIKM_03696 2.5e-115 rimJ2 J Acetyltransferase (GNAT) domain
MIIMCIKM_03697 5.5e-280 uxaC 5.3.1.12 G glucuronate isomerase
MIIMCIKM_03698 1.5e-160 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MIIMCIKM_03699 2e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_03700 1.7e-134 xytR K DeoR C terminal sensor domain
MIIMCIKM_03701 4.5e-89 ywrA P COG2059 Chromate transport protein ChrA
MIIMCIKM_03702 5.2e-107 ywrB P COG2059 Chromate transport protein ChrA
MIIMCIKM_03703 4.4e-160 mqnD S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MIIMCIKM_03704 8.2e-94 mqnB 2.4.2.1, 3.2.2.26, 3.2.2.9 F Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MIIMCIKM_03705 9.4e-89 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MIIMCIKM_03706 7.6e-244 G COG2182 Maltose-binding periplasmic proteins domains
MIIMCIKM_03707 2.1e-249 malC P COG1175 ABC-type sugar transport systems, permease components
MIIMCIKM_03708 3.5e-149 malG P transport
MIIMCIKM_03709 2.8e-188 malR 5.1.1.1 K Transcriptional regulator
MIIMCIKM_03710 1.2e-241 atoE I Short chain fatty acid transporter
MIIMCIKM_03711 5.6e-132 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MIIMCIKM_03712 2.8e-114 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MIIMCIKM_03713 0.0 ubiD 4.1.1.98 H Belongs to the UbiD family
MIIMCIKM_03714 6.9e-189 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MIIMCIKM_03715 1.4e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MIIMCIKM_03716 2.2e-229 yciC S GTPases (G3E family)
MIIMCIKM_03717 2.5e-40 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIIMCIKM_03718 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MIIMCIKM_03719 7.9e-149 degV S protein conserved in bacteria
MIIMCIKM_03720 2e-109 S DUF218 domain
MIIMCIKM_03722 2.8e-57 K Transcriptional regulator
MIIMCIKM_03723 9.9e-118 M1-1017 S Protein of unknown function (DUF1129)
MIIMCIKM_03724 2.3e-09
MIIMCIKM_03725 8e-231 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MIIMCIKM_03726 1.5e-67 CO cell redox homeostasis
MIIMCIKM_03727 4.2e-164 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_03728 1.4e-173 P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIIMCIKM_03729 0.0 appA_2 E COG0747 ABC-type dipeptide transport system, periplasmic component
MIIMCIKM_03730 5e-187 E Belongs to the ABC transporter superfamily
MIIMCIKM_03731 1.8e-187 oppD P Belongs to the ABC transporter superfamily
MIIMCIKM_03732 2.2e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MIIMCIKM_03733 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MIIMCIKM_03734 1.7e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MIIMCIKM_03735 3e-201 bkdA1 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MIIMCIKM_03736 1.1e-68 recN L Putative cell-wall binding lipoprotein
MIIMCIKM_03737 5.3e-17 S Protein of unknown function (Tiny_TM_bacill)
MIIMCIKM_03738 3e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MIIMCIKM_03739 2.4e-30 ykzG S Belongs to the UPF0356 family
MIIMCIKM_03740 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MIIMCIKM_03741 5.8e-115 ktrA P COG0569 K transport systems, NAD-binding component
MIIMCIKM_03742 9.1e-83 ykuV CO thiol-disulfide
MIIMCIKM_03743 4.7e-102 ykuU O Alkyl hydroperoxide reductase
MIIMCIKM_03744 7.8e-135 ykuT M Mechanosensitive ion channel
MIIMCIKM_03745 2.4e-37 ykuS S Belongs to the UPF0180 family
MIIMCIKM_03746 2.9e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MIIMCIKM_03747 7.1e-228 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
MIIMCIKM_03748 7.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MIIMCIKM_03749 6e-147 S Membrane transport protein
MIIMCIKM_03750 1.8e-192 T Metal dependent phosphohydrolases with conserved 'HD' motif.
MIIMCIKM_03751 9.8e-200 yhdY M Mechanosensitive ion channel
MIIMCIKM_03753 2.8e-97 copC S CopC domain
MIIMCIKM_03754 2e-184 ytvI S AI-2E family transporter
MIIMCIKM_03755 3.4e-112 GM NmrA-like family
MIIMCIKM_03756 1.2e-225 E Peptidase family M28
MIIMCIKM_03757 8.2e-193 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MIIMCIKM_03759 1.4e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
MIIMCIKM_03760 3.8e-28 copP P Heavy-metal-associated domain
MIIMCIKM_03761 2e-46 csoR S transcriptional
MIIMCIKM_03762 1e-30
MIIMCIKM_03763 7.4e-146 ykrA S hydrolases of the HAD superfamily
MIIMCIKM_03765 3.1e-59
MIIMCIKM_03766 2.9e-75 yqiW S Belongs to the UPF0403 family
MIIMCIKM_03767 6.7e-229 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MIIMCIKM_03768 5.7e-183 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MIIMCIKM_03769 1e-187 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MIIMCIKM_03770 8e-263 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MIIMCIKM_03771 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MIIMCIKM_03772 0.0 bkdR KT Transcriptional regulator
MIIMCIKM_03773 9.4e-36 yqzF S Protein of unknown function (DUF2627)
MIIMCIKM_03774 4.5e-119 2.7.8.33, 2.7.8.35 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIIMCIKM_03775 7.1e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MIIMCIKM_03776 2.2e-240 rseP 3.4.21.116 M Stage IV sporulation protein B
MIIMCIKM_03777 3.8e-296 recN L May be involved in recombinational repair of damaged DNA
MIIMCIKM_03778 4.6e-79 argR K Regulates arginine biosynthesis genes
MIIMCIKM_03779 1.4e-150 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MIIMCIKM_03780 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MIIMCIKM_03781 3.3e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MIIMCIKM_03782 9.7e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIIMCIKM_03783 1.5e-253 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MIIMCIKM_03784 1.1e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIIMCIKM_03785 3.1e-66 yqhY S protein conserved in bacteria
MIIMCIKM_03786 1.1e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MIIMCIKM_03787 2.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MIIMCIKM_03788 1.1e-56
MIIMCIKM_03789 1.2e-89 spoIIIAH S SpoIIIAH-like protein
MIIMCIKM_03790 6.4e-114 spoIIIAG S stage III sporulation protein AG
MIIMCIKM_03791 9.2e-96 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MIIMCIKM_03792 3.8e-205 spoIIIAE S stage III sporulation protein AE
MIIMCIKM_03793 1.6e-40 spoIIIAD S Stage III sporulation protein AD
MIIMCIKM_03794 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MIIMCIKM_03795 4.5e-54 yqjY K Acetyltransferase (GNAT) domain
MIIMCIKM_03796 7.1e-136 yoaT S Protein of unknown function (DUF817)
MIIMCIKM_03797 7.4e-30 K Transcriptional regulator
MIIMCIKM_03798 5.4e-62 yoaS S Protein of unknown function (DUF2975)
MIIMCIKM_03800 1.1e-121 S response regulator aspartate phosphatase
MIIMCIKM_03801 2.8e-157 kbaY 4.1.2.13, 4.1.2.40 G in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
MIIMCIKM_03802 1.8e-195 gatD 1.1.1.14, 1.1.1.251 C Alcohol dehydrogenase GroES-like domain
MIIMCIKM_03803 5.9e-239 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
MIIMCIKM_03804 1e-41 gatB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
MIIMCIKM_03805 1.7e-79 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MIIMCIKM_03806 5.6e-141 K COG1349 Transcriptional regulators of sugar metabolism
MIIMCIKM_03807 1.3e-179 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MIIMCIKM_03808 3.6e-91 S Protein of unknown function with HXXEE motif
MIIMCIKM_03809 2.4e-08
MIIMCIKM_03810 2.4e-78
MIIMCIKM_03811 1e-84 S Protein of unknown function (DUF1648)
MIIMCIKM_03812 3e-90 glvR K Helix-turn-helix domain, rpiR family
MIIMCIKM_03813 2.7e-09 K transcriptional regulator
MIIMCIKM_03821 4.7e-87 ydcK S Belongs to the SprT family
MIIMCIKM_03822 3.9e-08
MIIMCIKM_03823 0.0 yhgF K COG2183 Transcriptional accessory protein
MIIMCIKM_03824 3.1e-118 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MIIMCIKM_03825 4.3e-141 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIIMCIKM_03826 3.3e-83 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MIIMCIKM_03827 3.7e-54 rsbV T Belongs to the anti-sigma-factor antagonist family
MIIMCIKM_03828 2.3e-187 rsbU 3.1.3.3 KT phosphatase
MIIMCIKM_03829 7.2e-74 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MIIMCIKM_03830 1.5e-53 rsbS T antagonist
MIIMCIKM_03831 3e-145 rsbR T Positive regulator of sigma-B
MIIMCIKM_03832 4.4e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MIIMCIKM_03833 8e-25 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MIIMCIKM_03834 1.4e-231 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIIMCIKM_03835 1.8e-187 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MIIMCIKM_03836 2e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MIIMCIKM_03837 1.6e-132 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MIIMCIKM_03838 1.2e-101 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MIIMCIKM_03839 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MIIMCIKM_03840 3.2e-77 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MIIMCIKM_03841 5.9e-149 ehuB ET Bacterial periplasmic substrate-binding proteins
MIIMCIKM_03842 5.5e-113 ehuC E Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03843 4e-119 ehuD E Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03844 1.3e-148 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MIIMCIKM_03845 4.6e-73 wecC 1.1.1.336 M ArpU family transcriptional regulator
MIIMCIKM_03846 2.2e-261 malK 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MIIMCIKM_03847 8.4e-112 dcuR T COG4565 Response regulator of citrate malate metabolism
MIIMCIKM_03848 6.1e-244 maeN C COG3493 Na citrate symporter
MIIMCIKM_03849 1.4e-212 mez_1 1.1.1.38 C Malate dehydrogenase
MIIMCIKM_03850 1.4e-150 S Short C-terminal domain
MIIMCIKM_03851 3.3e-71
MIIMCIKM_03852 1.5e-77
MIIMCIKM_03853 8.5e-161 D Phage tail tape measure protein, TP901 family
MIIMCIKM_03854 9.1e-138 S Phage tail protein
MIIMCIKM_03855 0.0 L Phage minor structural protein
MIIMCIKM_03857 2.9e-76 S Bacteriophage holin family
MIIMCIKM_03858 0.0 G Bacterial extracellular solute-binding protein
MIIMCIKM_03859 3.7e-307 2.7.13.3 T Histidine kinase
MIIMCIKM_03860 9.4e-228 T cheY-homologous receiver domain
MIIMCIKM_03861 2e-172 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03862 3.5e-160 U Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03863 7.4e-39
MIIMCIKM_03864 8.4e-102 yvrI K RNA polymerase
MIIMCIKM_03865 8.9e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
MIIMCIKM_03866 2.4e-250 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MIIMCIKM_03867 1.3e-170 agpT K AraC-like ligand binding domain
MIIMCIKM_03868 9.4e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MIIMCIKM_03869 1.9e-206 desK 2.7.13.3 T Histidine kinase
MIIMCIKM_03870 9e-107 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIIMCIKM_03871 5.6e-189 mgtE P Acts as a magnesium transporter
MIIMCIKM_03872 4.6e-76 K transcriptional
MIIMCIKM_03873 5.5e-56
MIIMCIKM_03874 2.5e-89 3.1.1.29 K -acetyltransferase
MIIMCIKM_03875 8e-246 aspT EK Alanine-glyoxylate amino-transferase
MIIMCIKM_03876 1.9e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MIIMCIKM_03877 2.3e-41 ylxP S protein conserved in bacteria
MIIMCIKM_03878 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MIIMCIKM_03879 1.9e-47 ylxQ J ribosomal protein
MIIMCIKM_03880 9.4e-43 ylxR K nucleic-acid-binding protein implicated in transcription termination
MIIMCIKM_03881 5.2e-201 nusA K Participates in both transcription termination and antitermination
MIIMCIKM_03882 5.6e-80 rimP S Required for maturation of 30S ribosomal subunits
MIIMCIKM_03883 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MIIMCIKM_03884 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MIIMCIKM_03885 3.1e-234 rasP M zinc metalloprotease
MIIMCIKM_03886 7e-209 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MIIMCIKM_03887 1.6e-130 cdsA 2.7.7.41 S Belongs to the CDS family
MIIMCIKM_03888 9.7e-146 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIIMCIKM_03889 7.1e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MIIMCIKM_03890 7.4e-124 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MIIMCIKM_03891 4.4e-150 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MIIMCIKM_03892 1.6e-79 rpsB J Belongs to the universal ribosomal protein uS2 family
MIIMCIKM_03893 1.6e-144 ywfM EG EamA-like transporter family
MIIMCIKM_03895 5.3e-56 yitW S metal-sulfur cluster biosynthetic enzyme
MIIMCIKM_03897 1.8e-281 metP S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MIIMCIKM_03898 7.7e-160 ydeE K AraC family transcriptional regulator
MIIMCIKM_03899 1.1e-97 padR K Virulence activator alpha C-term
MIIMCIKM_03900 4e-86 S Domain of unknown function (DUF4188)
MIIMCIKM_03901 4.8e-216 blt9 EGP Major facilitator Superfamily
MIIMCIKM_03902 1.7e-139
MIIMCIKM_03903 6.4e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
MIIMCIKM_03904 5.9e-10 yxlE S Phospholipase_D-nuclease N-terminal
MIIMCIKM_03905 1.3e-168 yxlF V ABC transporter, ATP-binding protein
MIIMCIKM_03906 1.4e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MIIMCIKM_03907 1.1e-95 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MIIMCIKM_03908 6.7e-07 S Family of unknown function (DUF5345)
MIIMCIKM_03909 3.1e-12
MIIMCIKM_03910 1.2e-30 mutT 3.6.1.55 F NUDIX domain
MIIMCIKM_03911 5.9e-185 3.4.11.5 I Alpha beta hydrolase
MIIMCIKM_03912 1.6e-71 S Bacterial PH domain
MIIMCIKM_03913 1.9e-44 CP_0264 3.2.2.10 S Belongs to the LOG family
MIIMCIKM_03914 2.8e-88 C HEAT repeats
MIIMCIKM_03915 1.4e-124 catB 2.3.1.28 V This enzyme is an effector of chloramphenicol resistance in bacteria
MIIMCIKM_03916 6.4e-295 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MIIMCIKM_03917 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MIIMCIKM_03918 1.6e-94 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MIIMCIKM_03919 1.9e-245 agcS E Sodium alanine symporter
MIIMCIKM_03920 4.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MIIMCIKM_03921 4.2e-310 yngK T Glycosyl hydrolase-like 10
MIIMCIKM_03922 0.0 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MIIMCIKM_03923 1.1e-267 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIIMCIKM_03924 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MIIMCIKM_03925 1e-125 treR K transcriptional
MIIMCIKM_03926 1.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MIIMCIKM_03927 1.9e-211 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MIIMCIKM_03928 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MIIMCIKM_03929 0.0 rhaA 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MIIMCIKM_03930 6.9e-181 K AraC-like ligand binding domain
MIIMCIKM_03931 9.8e-261 yhdG E amino acid
MIIMCIKM_03932 3.2e-172 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MIIMCIKM_03933 3e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MIIMCIKM_03934 5.5e-121 K helix_turn_helix, arabinose operon control protein
MIIMCIKM_03935 4.6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_03936 6.5e-186
MIIMCIKM_03937 3.7e-105 ykoP G polysaccharide deacetylase
MIIMCIKM_03938 5.1e-198 S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_03939 2.9e-181 G Xylose isomerase-like TIM barrel
MIIMCIKM_03940 6.3e-128 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MIIMCIKM_03941 4.3e-158 G COG0395 ABC-type sugar transport system, permease component
MIIMCIKM_03942 1.1e-175 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03943 6.5e-93 K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MIIMCIKM_03944 1.4e-152 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MIIMCIKM_03945 4.8e-232 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MIIMCIKM_03946 7e-101 folE 3.5.4.16 H GTP cyclohydrolase
MIIMCIKM_03947 1.6e-35 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MIIMCIKM_03948 4.3e-58 hepS 2.5.1.30 H heptaprenyl diphosphate synthase
MIIMCIKM_03949 3.3e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MIIMCIKM_03950 3.9e-159 ubiA 2.5.1.39 H UbiA prenyltransferase family
MIIMCIKM_03951 3.7e-162 mqnA 1.21.98.1, 4.2.1.151 S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MIIMCIKM_03952 8.6e-184 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MIIMCIKM_03953 1.4e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MIIMCIKM_03954 8.4e-145 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MIIMCIKM_03955 4.1e-220 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MIIMCIKM_03956 1.5e-197 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIIMCIKM_03957 3.3e-59 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MIIMCIKM_03958 1.3e-284 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIIMCIKM_03959 1e-187 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIIMCIKM_03960 3.6e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MIIMCIKM_03961 2.9e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MIIMCIKM_03962 2.3e-226 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MIIMCIKM_03963 2.4e-147 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MIIMCIKM_03964 3.4e-208 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIIMCIKM_03967 1.7e-173 L Endonuclease/Exonuclease/phosphatase family
MIIMCIKM_03968 2.3e-136 2.1.1.301 Q Methyltransferase domain
MIIMCIKM_03969 4.3e-141 K helix_turn_helix, mercury resistance
MIIMCIKM_03970 3.8e-162 aacA-aphD 2.7.1.190 S Protein of unknown function (DUF1679)
MIIMCIKM_03971 1.1e-116 O Sap, sulfolipid-1-addressing protein
MIIMCIKM_03972 1.2e-71
MIIMCIKM_03973 6.1e-143 K MerR family transcriptional regulator
MIIMCIKM_03974 2.1e-165 K Acetyltransferase (GNAT) family
MIIMCIKM_03975 1.1e-190 MA20_01110 4.2.1.81 M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
MIIMCIKM_03976 3.2e-134 KT Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding
MIIMCIKM_03978 2.7e-113 S Protein of unknown function (DUF2812)
MIIMCIKM_03979 1e-48 padR K Transcriptional regulator PadR-like family
MIIMCIKM_03980 2.6e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MIIMCIKM_03981 8.3e-24 K Helix-turn-helix domain
MIIMCIKM_03982 1.6e-71
MIIMCIKM_03983 5.2e-77 rimL 2.3.1.128 J Acetyltransferase (GNAT) domain
MIIMCIKM_03984 1.3e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MIIMCIKM_03985 1.4e-189 yhfX E Alanine racemase, N-terminal domain
MIIMCIKM_03986 4.9e-229 yhfW G Metalloenzyme superfamily
MIIMCIKM_03988 0.0 O DnaJ molecular chaperone homology domain
MIIMCIKM_03989 0.0 hscC O Hsp70 protein
MIIMCIKM_03990 1.9e-141 IQ Enoyl-(Acyl carrier protein) reductase
MIIMCIKM_03991 2.1e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MIIMCIKM_03992 7.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MIIMCIKM_03993 3e-175 agpT K AraC-like ligand binding domain
MIIMCIKM_03994 7e-250 ugpB1 G Bacterial extracellular solute-binding protein
MIIMCIKM_03995 2.4e-148 M1-465 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03996 2.3e-159 P Binding-protein-dependent transport system inner membrane component
MIIMCIKM_03997 1.2e-48 esxA S Belongs to the WXG100 family
MIIMCIKM_03998 7.2e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
MIIMCIKM_03999 4.1e-213 essB S WXG100 protein secretion system (Wss), protein YukC
MIIMCIKM_04000 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MIIMCIKM_04001 0.0 esaA S domain protein
MIIMCIKM_04002 7.9e-71 S Family of unknown function (DUF5383)
MIIMCIKM_04003 2.4e-44
MIIMCIKM_04004 4.3e-47
MIIMCIKM_04005 9.9e-46
MIIMCIKM_04006 1.5e-283 S nuclease activity
MIIMCIKM_04007 2.3e-07
MIIMCIKM_04008 4.6e-88
MIIMCIKM_04009 4.4e-09
MIIMCIKM_04012 8.9e-07
MIIMCIKM_04013 2.7e-47
MIIMCIKM_04014 5.4e-10 S nuclease activity
MIIMCIKM_04018 3.5e-51
MIIMCIKM_04020 3.2e-49
MIIMCIKM_04022 3.3e-171 glcA G Glycoside hydrolase family 16
MIIMCIKM_04023 7.1e-17
MIIMCIKM_04028 3.1e-130 lolD-2 V COG1136 ABC-type antimicrobial peptide transport system, ATPase component
MIIMCIKM_04029 0.0 Q FtsX-like permease family
MIIMCIKM_04030 3.2e-89 K Transcriptional regulator PadR-like family
MIIMCIKM_04031 3.3e-80 2.3.1.128 K Acetyltransferase (GNAT) domain
MIIMCIKM_04032 1.7e-140 K Helix-turn-helix domain, rpiR family
MIIMCIKM_04033 7.6e-118 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MIIMCIKM_04034 4e-284 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIIMCIKM_04035 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MIIMCIKM_04036 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MIIMCIKM_04037 0.0 narH 1.7.5.1 C Nitrate reductase, beta
MIIMCIKM_04038 1.3e-116 narJ C Nitrate reductase delta subunit
MIIMCIKM_04039 2e-126 narI 1.7.5.1 C nitrate reductase, gamma subunit
MIIMCIKM_04040 2.4e-83 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
MIIMCIKM_04041 3.6e-199 nreB 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MIIMCIKM_04042 1.7e-114 nreC T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MIIMCIKM_04043 2.9e-279 narK P COG2223 Nitrate nitrite transporter
MIIMCIKM_04044 6.8e-26 M COG3209 Rhs family protein
MIIMCIKM_04045 5.7e-89 S Domain of unknown function (DUF1837)
MIIMCIKM_04046 1e-252 L Dead deah box helicase domain protein
MIIMCIKM_04047 7e-78 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIIMCIKM_04048 7.1e-08 S YyzF-like protein
MIIMCIKM_04049 5e-197 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIIMCIKM_04050 1.1e-147 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MIIMCIKM_04051 2.9e-157 yycI S protein conserved in bacteria
MIIMCIKM_04052 1e-251 yycH S protein conserved in bacteria
MIIMCIKM_04053 0.0 vicK 2.7.13.3 T Histidine kinase
MIIMCIKM_04054 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_04060 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MIIMCIKM_04061 2.1e-114 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MIIMCIKM_04062 4.3e-170 E Sodium:solute symporter family
MIIMCIKM_04063 3.5e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MIIMCIKM_04064 1.2e-252 3.2.1.51, 4.2.2.23 GH95,PL11 G Right handed beta helix region
MIIMCIKM_04065 5.7e-88 S Protein of unknown function (DUF664)
MIIMCIKM_04067 1.7e-148 drrB V Transport permease protein
MIIMCIKM_04068 2.7e-177 drrA V COG1131 ABC-type multidrug transport system, ATPase component
MIIMCIKM_04069 5.1e-268 EGP Major facilitator Superfamily
MIIMCIKM_04070 1e-165 K Bacterial regulatory proteins, tetR family
MIIMCIKM_04072 2.7e-216 yhbH S Belongs to the UPF0229 family
MIIMCIKM_04073 3.4e-140 cysA1 S AAA domain
MIIMCIKM_04074 1.4e-104 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MIIMCIKM_04075 0.0 prkA T Ser protein kinase
MIIMCIKM_04076 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MIIMCIKM_04077 2.2e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MIIMCIKM_04078 3.4e-255 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MIIMCIKM_04080 3.3e-258 C FAD dependent oxidoreductase
MIIMCIKM_04081 1.5e-147 G Binding-protein-dependent transport system inner membrane component
MIIMCIKM_04082 8e-171 U Binding-protein-dependent transport system inner membrane component
MIIMCIKM_04083 1.6e-246 G Bacterial extracellular solute-binding protein
MIIMCIKM_04084 0.0 2.7.13.3 T Histidine kinase
MIIMCIKM_04085 4.2e-138 T helix_turn_helix, arabinose operon control protein
MIIMCIKM_04086 2.8e-265 G beta-fructofuranosidase activity
MIIMCIKM_04088 3.7e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MIIMCIKM_04089 4.4e-58 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MIIMCIKM_04090 8.4e-287 uxaA 4.2.1.7 G Altronate
MIIMCIKM_04091 2e-288 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MIIMCIKM_04092 9.1e-173 sorC K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MIIMCIKM_04093 8.9e-75 gutM K Glucitol operon activator
MIIMCIKM_04094 4.3e-98 srlA G PTS system enzyme II sorbitol-specific factor
MIIMCIKM_04095 1.4e-176 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
MIIMCIKM_04096 1.3e-55 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MIIMCIKM_04097 1.7e-142 C KR domain
MIIMCIKM_04098 6.6e-158 chiA 3.2.1.14, 3.2.1.17 AA10,CBM15,CBM73,GH18 D Lytic polysaccharide mono-oxygenase, cellulose-degrading
MIIMCIKM_04099 9.6e-32 S Sporulation inhibitor A
MIIMCIKM_04100 1.5e-100 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MIIMCIKM_04101 9.2e-210 siaM G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MIIMCIKM_04102 1.3e-76 G Tripartite ATP-independent periplasmic transporters, DctQ component
MIIMCIKM_04103 3.1e-184 G Bacterial extracellular solute-binding protein, family 7
MIIMCIKM_04104 1.6e-115 K FCD
MIIMCIKM_04105 1.5e-194 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MIIMCIKM_04106 3e-263 NT chemotaxis protein
MIIMCIKM_04107 1.1e-89 paiA K Acetyltransferase (GNAT) domain
MIIMCIKM_04108 9.9e-97 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MIIMCIKM_04109 1.1e-184 S Domain of unknown function (DUF4179)
MIIMCIKM_04110 3.8e-75 S Domain of unknown function (DU1801)
MIIMCIKM_04111 8.5e-116 S CGNR zinc finger
MIIMCIKM_04113 2.8e-84
MIIMCIKM_04114 4.5e-269 cstA T Carbon starvation protein
MIIMCIKM_04115 3.6e-134 T COG3279 Response regulator of the LytR AlgR family
MIIMCIKM_04116 0.0 lytS 2.7.13.3 T Histidine kinase
MIIMCIKM_04117 2.1e-85 isdE P ABC transporter substrate-binding protein
MIIMCIKM_04118 2.2e-171 fhuB11 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIIMCIKM_04119 1.8e-136 fhuC 3.6.3.28, 3.6.3.34 HP ABC transporter, ATP-binding protein
MIIMCIKM_04120 2e-143 srtB 3.4.22.70 S Sortase family
MIIMCIKM_04121 1.1e-242 yhdP S COG1253 Hemolysins and related proteins containing CBS domains
MIIMCIKM_04122 4.8e-162 opuAC E Glycine betaine ABC transporter
MIIMCIKM_04123 2.5e-261 S Predicted membrane protein (DUF2254)
MIIMCIKM_04124 3.4e-174 P Catalase
MIIMCIKM_04125 3.1e-169 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MIIMCIKM_04126 1e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MIIMCIKM_04128 2.1e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MIIMCIKM_04129 3.9e-113 Q Methyltransferase domain
MIIMCIKM_04130 1.3e-60 gntR1 K helix_turn_helix gluconate operon transcriptional repressor
MIIMCIKM_04131 5.3e-164 V ATPases associated with a variety of cellular activities
MIIMCIKM_04132 2.9e-128
MIIMCIKM_04133 3.6e-157 acrR_2 K Transcriptional regulator
MIIMCIKM_04134 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MIIMCIKM_04135 1.1e-09 yaaB S Domain of unknown function (DUF370)
MIIMCIKM_04136 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MIIMCIKM_04137 9.1e-33 yaaA S S4 domain
MIIMCIKM_04138 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MIIMCIKM_04139 1.3e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIIMCIKM_04140 1.9e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MIIMCIKM_04141 6e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MIIMCIKM_04142 3.9e-127 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MIIMCIKM_04143 2.6e-112 jag S single-stranded nucleic acid binding R3H
MIIMCIKM_04145 3.2e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MIIMCIKM_04146 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MIIMCIKM_04147 3.8e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MIIMCIKM_04148 7.9e-149 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MIIMCIKM_04149 2e-135 soj D COG1192 ATPases involved in chromosome partitioning
MIIMCIKM_04150 4.2e-141 J Putative SAM-dependent methyltransferase
MIIMCIKM_04151 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MIIMCIKM_04152 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MIIMCIKM_04153 2.6e-103 cotE S Spore coat protein
MIIMCIKM_04154 8.9e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MIIMCIKM_04155 4.7e-304 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MIIMCIKM_04156 7e-155 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MIIMCIKM_04157 6.7e-38 spoVS S Stage V sporulation protein S
MIIMCIKM_04158 3.4e-154 ymdB S protein conserved in bacteria
MIIMCIKM_04159 1.8e-218 rny S Endoribonuclease that initiates mRNA decay
MIIMCIKM_04160 4e-116 L DNA recombination
MIIMCIKM_04162 8.7e-265 sbcC L AAA domain
MIIMCIKM_04163 1.5e-133 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MIIMCIKM_04164 4.2e-207 mntH P H( )-stimulated, divalent metal cation uptake system
MIIMCIKM_04165 2.4e-113 S HTH domain
MIIMCIKM_04166 1.1e-188 speB 3.5.3.11 E Arginase family
MIIMCIKM_04167 1.1e-127 T Transcriptional regulator
MIIMCIKM_04168 1.5e-203 T PhoQ Sensor
MIIMCIKM_04169 2.2e-165 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MIIMCIKM_04170 4.2e-124 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MIIMCIKM_04171 7.6e-117 ydfE S Flavin reductase like domain
MIIMCIKM_04172 8.1e-115 S ABC-2 family transporter protein
MIIMCIKM_04173 8.3e-168 ycbN V ABC transporter, ATP-binding protein
MIIMCIKM_04174 5.1e-165 T PhoQ Sensor
MIIMCIKM_04175 1.2e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MIIMCIKM_04176 0.0 M Domain of unknown function DUF11
MIIMCIKM_04177 6.1e-238 cycB G COG2182 Maltose-binding periplasmic proteins domains
MIIMCIKM_04178 1.1e-245 malC P COG1175 ABC-type sugar transport systems, permease components
MIIMCIKM_04179 9.3e-150 ganQ P transport
MIIMCIKM_04180 4.4e-238 ganB 3.2.1.89 G arabinogalactan
MIIMCIKM_04181 0.0 lacA 3.2.1.23 G beta-galactosidase
MIIMCIKM_04182 6.8e-129 S response regulator aspartate phosphatase
MIIMCIKM_04184 2.2e-101 S DinB superfamily
MIIMCIKM_04185 8.4e-212 dapE 3.5.1.18 E Peptidase dimerisation domain
MIIMCIKM_04186 1.5e-202 6.3.5.5 S ATP-grasp domain
MIIMCIKM_04187 2.4e-69 K helix_turn_helix, mercury resistance
MIIMCIKM_04188 3.5e-58 S Domain of unknown function (DUF4260)
MIIMCIKM_04189 6.4e-159 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylases
MIIMCIKM_04190 2.2e-229 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MIIMCIKM_04191 1.4e-251 agcS E Sodium alanine symporter
MIIMCIKM_04192 7.2e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MIIMCIKM_04193 2.5e-43 ywcE S Required for proper spore morphogenesis. Important for spore germination
MIIMCIKM_04194 4.8e-51 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MIIMCIKM_04195 4.7e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MIIMCIKM_04196 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIIMCIKM_04197 1.7e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MIIMCIKM_04198 7.8e-44 S DNA alkylation repair protein
MIIMCIKM_04199 4e-220 I COG0657 Esterase lipase
MIIMCIKM_04200 1.5e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIIMCIKM_04201 5.1e-53 yneR S Belongs to the HesB IscA family
MIIMCIKM_04203 3.8e-162 cheV 2.7.13.3 T Chemotaxis protein CheV
MIIMCIKM_04204 4.4e-177 3.4.13.19 E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
MIIMCIKM_04205 3.9e-72 hspX O Belongs to the small heat shock protein (HSP20) family
MIIMCIKM_04206 2.3e-29 S YppG-like protein
MIIMCIKM_04207 7.9e-23
MIIMCIKM_04208 6.1e-235 ykuI T Diguanylate phosphodiesterase
MIIMCIKM_04209 3.6e-154 I Hydrolase
MIIMCIKM_04210 7.9e-179 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIIMCIKM_04211 2e-80 S Domain of unknown function (DUF4352)
MIIMCIKM_04212 1.5e-155 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MIIMCIKM_04213 1.7e-75 S thioesterase
MIIMCIKM_04214 0.0 spoVK O stage V sporulation protein K
MIIMCIKM_04215 5.6e-143 P Copper resistance protein D
MIIMCIKM_04216 1.2e-11 sspN S Small acid-soluble spore protein N family
MIIMCIKM_04218 7.9e-282 L COG3666 Transposase and inactivated derivatives
MIIMCIKM_04219 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIIMCIKM_04221 4.9e-13
MIIMCIKM_04222 3.9e-81 yneK S Protein of unknown function (DUF2621)
MIIMCIKM_04223 0.0 mdlB V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIIMCIKM_04224 0.0 mdlA V COG1132 ABC-type multidrug transport system, ATPase and permease components
MIIMCIKM_04225 7.9e-29 yneF S UPF0154 protein
MIIMCIKM_04226 4.2e-74 yneE S Sporulation inhibitor of replication protein sirA
MIIMCIKM_04227 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIIMCIKM_04228 4.2e-34 ynzC S UPF0291 protein
MIIMCIKM_04229 6.6e-119 yneB L resolvase
MIIMCIKM_04231 2.6e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MIIMCIKM_04232 3.2e-220 yuxJ EGP Major facilitator Superfamily
MIIMCIKM_04234 4.2e-214 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIIMCIKM_04235 4e-98 MA20_21960 FG Domain of unknown function (DUF4269)
MIIMCIKM_04236 6.7e-90
MIIMCIKM_04237 1.2e-137 K helix_turn_helix isocitrate lyase regulation
MIIMCIKM_04238 7.6e-143 Q Domain of unknown function (DUF2437)
MIIMCIKM_04239 0.0 glcB 2.3.3.9 C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MIIMCIKM_04240 1.1e-280 glcD 1.1.2.4, 1.1.3.15 C FAD linked oxidases, C-terminal domain
MIIMCIKM_04241 2.3e-267 glcF C Glycolate oxidase
MIIMCIKM_04242 4.5e-252 glcE C FAD binding domain
MIIMCIKM_04243 1.3e-75 M Acetyltransferase (GNAT) domain
MIIMCIKM_04244 2.1e-265 glnA 6.3.1.2 E glutamine synthetase
MIIMCIKM_04245 9.6e-247 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MIIMCIKM_04246 7.6e-169 spoVK O stage V sporulation protein K
MIIMCIKM_04247 2.9e-190 xerD L Belongs to the 'phage' integrase family
MIIMCIKM_04248 2.7e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MIIMCIKM_04249 9.2e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)