ORF_ID e_value Gene_name EC_number CAZy COGs Description
GFNHDNMA_00001 5.7e-78 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GFNHDNMA_00002 3.8e-71 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GFNHDNMA_00004 5.5e-217 KQ helix_turn_helix, mercury resistance
GFNHDNMA_00005 5.4e-208 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GFNHDNMA_00006 2.2e-165 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GFNHDNMA_00007 5.7e-117 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GFNHDNMA_00008 4.1e-189 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GFNHDNMA_00009 8.9e-74 K Putative DNA-binding domain
GFNHDNMA_00010 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
GFNHDNMA_00011 2.3e-146 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GFNHDNMA_00012 3.1e-42 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GFNHDNMA_00013 1.2e-80 S CRISPR-associated protein (Cas_Csn2)
GFNHDNMA_00016 7.4e-09
GFNHDNMA_00018 2.4e-69 S HIRAN
GFNHDNMA_00019 2.9e-141 htpX O Peptidase family M48
GFNHDNMA_00021 2.8e-61
GFNHDNMA_00022 1.5e-79 mutT 3.6.1.55 F NUDIX domain
GFNHDNMA_00023 1.1e-33
GFNHDNMA_00024 8e-67
GFNHDNMA_00025 2.7e-64 S Domain of unknown function DUF1828
GFNHDNMA_00026 6.4e-90 S Rib/alpha-like repeat
GFNHDNMA_00028 2.1e-244 yagE E amino acid
GFNHDNMA_00029 5.1e-116 GM NmrA-like family
GFNHDNMA_00030 1.8e-150 xerD L Phage integrase, N-terminal SAM-like domain
GFNHDNMA_00031 4.6e-90 dedA 3.1.3.1 S SNARE associated Golgi protein
GFNHDNMA_00032 7e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
GFNHDNMA_00033 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GFNHDNMA_00034 1.7e-240 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GFNHDNMA_00035 0.0 oatA I Acyltransferase
GFNHDNMA_00036 3e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GFNHDNMA_00037 1.2e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GFNHDNMA_00038 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
GFNHDNMA_00039 6.6e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GFNHDNMA_00040 5.5e-305 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
GFNHDNMA_00041 2e-26 S Protein of unknown function (DUF2929)
GFNHDNMA_00042 0.0 dnaE 2.7.7.7 L DNA polymerase
GFNHDNMA_00043 3.6e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GFNHDNMA_00044 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GFNHDNMA_00045 1.2e-166 cvfB S S1 domain
GFNHDNMA_00046 2.2e-165 xerD D recombinase XerD
GFNHDNMA_00047 1.8e-62 ribT K acetyltransferase
GFNHDNMA_00048 1.7e-134 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GFNHDNMA_00049 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GFNHDNMA_00050 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GFNHDNMA_00051 7.4e-58 M Lysin motif
GFNHDNMA_00052 6.4e-97 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GFNHDNMA_00053 6.2e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GFNHDNMA_00054 6e-219 rpsA 1.17.7.4 J Ribosomal protein S1
GFNHDNMA_00055 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GFNHDNMA_00056 6.7e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GFNHDNMA_00057 5.1e-229 S Tetratricopeptide repeat protein
GFNHDNMA_00058 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
GFNHDNMA_00060 1.4e-251 hsdM 2.1.1.72 V type I restriction-modification system
GFNHDNMA_00061 2.9e-90 3.1.21.3 V Type I restriction modification DNA specificity domain
GFNHDNMA_00062 3e-150 S KAP family P-loop domain
GFNHDNMA_00063 2.4e-30 mrr L restriction endonuclease
GFNHDNMA_00064 1.9e-14 M LysM domain
GFNHDNMA_00065 4.1e-08 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GFNHDNMA_00066 7.2e-135 mrr L restriction endonuclease
GFNHDNMA_00068 3e-299 1.3.5.4 C FMN_bind
GFNHDNMA_00069 1.7e-80
GFNHDNMA_00070 2e-36 menA 2.5.1.74 H UbiA prenyltransferase family
GFNHDNMA_00071 9.9e-34 menA 2.5.1.74 H UbiA prenyltransferase family
GFNHDNMA_00072 2.5e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFNHDNMA_00073 6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GFNHDNMA_00074 5.8e-115 hlyIII S protein, hemolysin III
GFNHDNMA_00075 1.6e-149 DegV S Uncharacterised protein, DegV family COG1307
GFNHDNMA_00076 1.6e-35 yozE S Belongs to the UPF0346 family
GFNHDNMA_00077 1.3e-260 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
GFNHDNMA_00078 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GFNHDNMA_00079 2.7e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GFNHDNMA_00080 1.2e-152 dprA LU DNA protecting protein DprA
GFNHDNMA_00081 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GFNHDNMA_00082 1.2e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GFNHDNMA_00083 4.4e-169 xerC D Phage integrase, N-terminal SAM-like domain
GFNHDNMA_00084 4.3e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GFNHDNMA_00085 1.8e-251 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GFNHDNMA_00086 8.5e-178 lacX 5.1.3.3 G Aldose 1-epimerase
GFNHDNMA_00087 2.5e-96 K LysR substrate binding domain
GFNHDNMA_00088 1.2e-100 S LexA-binding, inner membrane-associated putative hydrolase
GFNHDNMA_00090 5.5e-72
GFNHDNMA_00091 3.5e-208 L Putative transposase DNA-binding domain
GFNHDNMA_00092 1.7e-52 MA20_14895 S Conserved hypothetical protein 698
GFNHDNMA_00093 5.6e-104 MA20_14895 S Conserved hypothetical protein 698
GFNHDNMA_00095 1.2e-272 lsa S ABC transporter
GFNHDNMA_00096 1e-81 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
GFNHDNMA_00097 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GFNHDNMA_00098 3.4e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
GFNHDNMA_00099 3.1e-66 S Protein of unknown function (DUF3021)
GFNHDNMA_00100 2.4e-69 K LytTr DNA-binding domain
GFNHDNMA_00101 1.5e-14 sprD D Domain of Unknown Function (DUF1542)
GFNHDNMA_00102 0.0 sprD D Domain of Unknown Function (DUF1542)
GFNHDNMA_00103 3.1e-111 S Protein of unknown function (DUF1211)
GFNHDNMA_00104 6e-12 S reductase
GFNHDNMA_00105 1e-59 S reductase
GFNHDNMA_00106 3.7e-108 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GFNHDNMA_00107 7.6e-117 3.6.1.55 F NUDIX domain
GFNHDNMA_00108 8.2e-128 T Transcriptional regulatory protein, C terminal
GFNHDNMA_00109 3.2e-237 T GHKL domain
GFNHDNMA_00110 1.3e-87 S Peptidase propeptide and YPEB domain
GFNHDNMA_00111 3.7e-104 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
GFNHDNMA_00112 1.7e-51 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
GFNHDNMA_00113 4.9e-70 S Putative adhesin
GFNHDNMA_00114 4.6e-247 brnQ U Component of the transport system for branched-chain amino acids
GFNHDNMA_00115 5.8e-34 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GFNHDNMA_00116 1.3e-182 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GFNHDNMA_00117 1.9e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
GFNHDNMA_00118 1.6e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GFNHDNMA_00119 4.4e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GFNHDNMA_00120 1.3e-191 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GFNHDNMA_00121 1.1e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFNHDNMA_00122 8.6e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GFNHDNMA_00123 1.1e-217 aspC 2.6.1.1 E Aminotransferase
GFNHDNMA_00124 3.5e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GFNHDNMA_00125 1e-142 sufC O FeS assembly ATPase SufC
GFNHDNMA_00126 1.7e-221 sufD O FeS assembly protein SufD
GFNHDNMA_00127 1.2e-230 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GFNHDNMA_00128 1e-78 nifU C SUF system FeS assembly protein, NifU family
GFNHDNMA_00129 1.1e-272 sufB O assembly protein SufB
GFNHDNMA_00130 2.1e-54 yitW S Iron-sulfur cluster assembly protein
GFNHDNMA_00131 3.9e-268 mntH P H( )-stimulated, divalent metal cation uptake system
GFNHDNMA_00132 4.2e-138 H Nodulation protein S (NodS)
GFNHDNMA_00134 4.9e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GFNHDNMA_00135 8.2e-34 S PFAM Archaeal ATPase
GFNHDNMA_00137 9.6e-139 S PFAM Archaeal ATPase
GFNHDNMA_00138 0.0 uvrA3 L excinuclease ABC, A subunit
GFNHDNMA_00140 2.6e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
GFNHDNMA_00141 2.5e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GFNHDNMA_00142 6.7e-77 yphH S Cupin domain
GFNHDNMA_00143 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
GFNHDNMA_00144 9e-72 K helix_turn_helix multiple antibiotic resistance protein
GFNHDNMA_00145 0.0 lmrA 3.6.3.44 V ABC transporter
GFNHDNMA_00146 1.5e-157 C Aldo keto reductase
GFNHDNMA_00147 2e-18 K Transcriptional regulator
GFNHDNMA_00148 3.3e-236 yrvN L AAA C-terminal domain
GFNHDNMA_00149 9.3e-172 4.1.1.45 S Amidohydrolase
GFNHDNMA_00150 1.3e-32
GFNHDNMA_00151 3.6e-110 ybhL S Belongs to the BI1 family
GFNHDNMA_00152 6.6e-196
GFNHDNMA_00153 2.3e-229 S ABC-2 family transporter protein
GFNHDNMA_00154 8.9e-156 V ATPases associated with a variety of cellular activities
GFNHDNMA_00155 2.5e-166 akr5f 1.1.1.346 S reductase
GFNHDNMA_00156 1.4e-107 lacA 2.3.1.79 S Transferase hexapeptide repeat
GFNHDNMA_00157 4.9e-114 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GFNHDNMA_00158 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GFNHDNMA_00159 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GFNHDNMA_00160 8.2e-179 K Transcriptional regulator
GFNHDNMA_00161 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
GFNHDNMA_00162 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
GFNHDNMA_00163 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GFNHDNMA_00164 8.8e-122 yoaK S Protein of unknown function (DUF1275)
GFNHDNMA_00165 4.5e-202 xerS L Belongs to the 'phage' integrase family
GFNHDNMA_00166 3.4e-124 K Transcriptional regulator
GFNHDNMA_00167 1.4e-148
GFNHDNMA_00168 1.4e-161 degV S EDD domain protein, DegV family
GFNHDNMA_00169 6e-62
GFNHDNMA_00170 0.0 FbpA K Fibronectin-binding protein
GFNHDNMA_00171 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
GFNHDNMA_00172 5.3e-195 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GFNHDNMA_00173 6.1e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GFNHDNMA_00174 3.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GFNHDNMA_00175 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GFNHDNMA_00176 7.8e-55
GFNHDNMA_00177 2e-174 degV S DegV family
GFNHDNMA_00178 1.9e-219 I transferase activity, transferring acyl groups other than amino-acyl groups
GFNHDNMA_00179 4.1e-239 cpdA S Calcineurin-like phosphoesterase
GFNHDNMA_00180 1.1e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GFNHDNMA_00181 4.5e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GFNHDNMA_00182 1.5e-103 ypsA S Belongs to the UPF0398 family
GFNHDNMA_00183 1.3e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GFNHDNMA_00184 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
GFNHDNMA_00185 8.8e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GFNHDNMA_00186 3.7e-114 dnaD L DnaD domain protein
GFNHDNMA_00187 2.7e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
GFNHDNMA_00188 5.3e-89 ypmB S Protein conserved in bacteria
GFNHDNMA_00189 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GFNHDNMA_00190 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GFNHDNMA_00191 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GFNHDNMA_00192 9.1e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
GFNHDNMA_00193 2.1e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GFNHDNMA_00194 2.7e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GFNHDNMA_00195 9.1e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GFNHDNMA_00196 3.1e-279 V ABC-type multidrug transport system, ATPase and permease components
GFNHDNMA_00197 2.1e-274 V ABC-type multidrug transport system, ATPase and permease components
GFNHDNMA_00198 1.8e-226 L COG3547 Transposase and inactivated derivatives
GFNHDNMA_00199 2.1e-09 rnhA 3.1.26.4 L Caulimovirus viroplasmin
GFNHDNMA_00200 2.5e-204 G Transmembrane secretion effector
GFNHDNMA_00201 3.4e-157 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
GFNHDNMA_00202 2.1e-160 rbsU U ribose uptake protein RbsU
GFNHDNMA_00203 5.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GFNHDNMA_00204 1.3e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GFNHDNMA_00205 6.2e-84 6.3.3.2 S ASCH
GFNHDNMA_00206 9.5e-149 2.4.2.3 F Phosphorylase superfamily
GFNHDNMA_00207 9.2e-144 2.4.2.3 F Phosphorylase superfamily
GFNHDNMA_00208 1.8e-115 2.4.2.3 F Phosphorylase superfamily
GFNHDNMA_00209 2.5e-80 3.6.1.55 F NUDIX domain
GFNHDNMA_00210 1.4e-164 yxaM EGP Major facilitator Superfamily
GFNHDNMA_00211 7.6e-54 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
GFNHDNMA_00212 1.3e-92 S Alpha/beta hydrolase family
GFNHDNMA_00213 8.4e-15 S Alpha/beta hydrolase family
GFNHDNMA_00214 2.6e-109 XK27_07525 3.6.1.55 F NUDIX domain
GFNHDNMA_00215 6.6e-87 2.3.1.57 K Acetyltransferase (GNAT) family
GFNHDNMA_00216 9e-90 rimL J Acetyltransferase (GNAT) domain
GFNHDNMA_00217 1.9e-138 aroD S Serine hydrolase (FSH1)
GFNHDNMA_00218 2.5e-255 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFNHDNMA_00219 5.9e-43
GFNHDNMA_00220 1e-121 3.1.3.48 T Tyrosine phosphatase family
GFNHDNMA_00221 1.2e-61
GFNHDNMA_00222 3.4e-46 S MazG-like family
GFNHDNMA_00223 1.2e-82 FG HIT domain
GFNHDNMA_00224 1.3e-42
GFNHDNMA_00226 3.8e-73 K Acetyltransferase (GNAT) domain
GFNHDNMA_00227 3.6e-79
GFNHDNMA_00228 3.7e-107 speG J Acetyltransferase (GNAT) domain
GFNHDNMA_00229 9.4e-43
GFNHDNMA_00230 1.2e-51 S endonuclease activity
GFNHDNMA_00231 3.5e-49
GFNHDNMA_00232 1.4e-279 V ABC transporter transmembrane region
GFNHDNMA_00233 7.1e-78 C nitroreductase
GFNHDNMA_00234 5e-202 yhjX P Major Facilitator Superfamily
GFNHDNMA_00235 9.8e-244 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GFNHDNMA_00237 8.3e-75 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
GFNHDNMA_00238 7.7e-63
GFNHDNMA_00239 3.7e-293 V ABC-type multidrug transport system, ATPase and permease components
GFNHDNMA_00240 7.5e-185 P ABC transporter
GFNHDNMA_00241 7.8e-136 qmcA O prohibitin homologues
GFNHDNMA_00242 5.7e-10 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GFNHDNMA_00243 2.5e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GFNHDNMA_00244 2.7e-168 C Oxidoreductase
GFNHDNMA_00245 5.3e-113 drgA C nitroreductase
GFNHDNMA_00246 0.0 pepO 3.4.24.71 O Peptidase family M13
GFNHDNMA_00247 0.0 XK27_06780 V ABC transporter permease
GFNHDNMA_00248 1.5e-113 XK27_06785 V ABC transporter, ATP-binding protein
GFNHDNMA_00249 4.5e-107 alkD L DNA alkylation repair enzyme
GFNHDNMA_00250 3.5e-205 M Glycosyl transferases group 1
GFNHDNMA_00251 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GFNHDNMA_00252 5.9e-105 pncA Q Isochorismatase family
GFNHDNMA_00253 6.2e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GFNHDNMA_00254 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
GFNHDNMA_00255 2.4e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GFNHDNMA_00256 2.3e-232 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GFNHDNMA_00257 1.1e-178 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GFNHDNMA_00258 1.9e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GFNHDNMA_00259 1.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GFNHDNMA_00260 1.1e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GFNHDNMA_00261 1.2e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GFNHDNMA_00262 1.3e-301 I Protein of unknown function (DUF2974)
GFNHDNMA_00263 8.4e-148 yxeH S hydrolase
GFNHDNMA_00264 1.5e-173 XK27_05540 S DUF218 domain
GFNHDNMA_00265 2.1e-49 ybjQ S Belongs to the UPF0145 family
GFNHDNMA_00266 8.4e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
GFNHDNMA_00267 1.4e-173
GFNHDNMA_00268 2.7e-129
GFNHDNMA_00269 9.8e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GFNHDNMA_00270 4.7e-22
GFNHDNMA_00271 3.1e-137
GFNHDNMA_00272 1.2e-141
GFNHDNMA_00273 2.1e-123 skfE V ATPases associated with a variety of cellular activities
GFNHDNMA_00274 3.6e-58 yvoA_1 K Transcriptional regulator, GntR family
GFNHDNMA_00275 9.2e-247 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GFNHDNMA_00276 7.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GFNHDNMA_00277 1.6e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
GFNHDNMA_00278 5e-143 cjaA ET ABC transporter substrate-binding protein
GFNHDNMA_00279 4.5e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GFNHDNMA_00280 1.3e-106 P ABC transporter permease
GFNHDNMA_00281 1.3e-114 papP P ABC transporter, permease protein
GFNHDNMA_00282 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GFNHDNMA_00283 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GFNHDNMA_00284 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GFNHDNMA_00285 2.7e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GFNHDNMA_00286 5.2e-136 recO L Involved in DNA repair and RecF pathway recombination
GFNHDNMA_00287 9.6e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GFNHDNMA_00288 1.4e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GFNHDNMA_00289 7.3e-175 phoH T phosphate starvation-inducible protein PhoH
GFNHDNMA_00290 2.9e-33 yqeY S YqeY-like protein
GFNHDNMA_00291 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GFNHDNMA_00292 2.5e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GFNHDNMA_00293 4.1e-50 S Iron-sulfur cluster assembly protein
GFNHDNMA_00294 1e-151 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GFNHDNMA_00295 7.1e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
GFNHDNMA_00296 4.5e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFNHDNMA_00297 1.1e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GFNHDNMA_00299 1.4e-141 E GDSL-like Lipase/Acylhydrolase family
GFNHDNMA_00300 1.7e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GFNHDNMA_00301 1.2e-222 patA 2.6.1.1 E Aminotransferase
GFNHDNMA_00303 9.8e-169 phnD P Phosphonate ABC transporter
GFNHDNMA_00304 1.9e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GFNHDNMA_00305 5.4e-131 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
GFNHDNMA_00306 7.1e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
GFNHDNMA_00307 1.9e-83
GFNHDNMA_00308 3.1e-275 S Calcineurin-like phosphoesterase
GFNHDNMA_00309 0.0 asnB 6.3.5.4 E Asparagine synthase
GFNHDNMA_00310 1.4e-264 yxbA 6.3.1.12 S ATP-grasp enzyme
GFNHDNMA_00311 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GFNHDNMA_00312 1.5e-129 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GFNHDNMA_00313 7e-104 S Iron-sulfur cluster assembly protein
GFNHDNMA_00314 5.4e-228 XK27_04775 S PAS domain
GFNHDNMA_00315 2.6e-225 yttB EGP Major facilitator Superfamily
GFNHDNMA_00316 7.5e-183 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
GFNHDNMA_00317 1.4e-148 D nuclear chromosome segregation
GFNHDNMA_00318 5.7e-46 D nuclear chromosome segregation
GFNHDNMA_00319 2.9e-134 rpl K Helix-turn-helix domain, rpiR family
GFNHDNMA_00320 7e-167 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
GFNHDNMA_00321 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GFNHDNMA_00322 0.0 pepO 3.4.24.71 O Peptidase family M13
GFNHDNMA_00323 2.4e-311 S Bacterial membrane protein, YfhO
GFNHDNMA_00324 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
GFNHDNMA_00325 0.0 kup P Transport of potassium into the cell
GFNHDNMA_00326 0.0 kup P Transport of potassium into the cell
GFNHDNMA_00327 1e-72
GFNHDNMA_00328 7.2e-115
GFNHDNMA_00329 4.2e-27
GFNHDNMA_00330 8.2e-35 S Protein of unknown function (DUF2922)
GFNHDNMA_00331 5.7e-214 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GFNHDNMA_00332 9.9e-224 lysA2 M Glycosyl hydrolases family 25
GFNHDNMA_00333 3.6e-143 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
GFNHDNMA_00334 0.0 yjbQ P TrkA C-terminal domain protein
GFNHDNMA_00335 1e-176 S Oxidoreductase family, NAD-binding Rossmann fold
GFNHDNMA_00336 4.4e-138
GFNHDNMA_00337 4.2e-147
GFNHDNMA_00338 3.5e-73 S PAS domain
GFNHDNMA_00339 1.1e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GFNHDNMA_00340 8.1e-48 S HicB_like antitoxin of bacterial toxin-antitoxin system
GFNHDNMA_00341 9.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GFNHDNMA_00342 3.8e-70 2.4.1.83 GT2 S GtrA-like protein
GFNHDNMA_00343 2e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
GFNHDNMA_00344 1e-117
GFNHDNMA_00345 1.2e-152 glcU U sugar transport
GFNHDNMA_00346 2.2e-170 yqhA G Aldose 1-epimerase
GFNHDNMA_00347 9.5e-195 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GFNHDNMA_00348 6.2e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GFNHDNMA_00349 0.0 XK27_08315 M Sulfatase
GFNHDNMA_00350 3.1e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GFNHDNMA_00352 2.9e-259 pepC 3.4.22.40 E aminopeptidase
GFNHDNMA_00353 2.9e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GFNHDNMA_00354 3.3e-255 pepC 3.4.22.40 E aminopeptidase
GFNHDNMA_00355 9e-33
GFNHDNMA_00356 1.1e-75 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GFNHDNMA_00357 2.7e-73 hsp O Belongs to the small heat shock protein (HSP20) family
GFNHDNMA_00358 9.9e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GFNHDNMA_00359 7.5e-83
GFNHDNMA_00360 1.9e-75 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GFNHDNMA_00361 1.3e-143 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GFNHDNMA_00362 5.2e-130 yydK K UTRA
GFNHDNMA_00363 4.9e-72 S Domain of unknown function (DUF3284)
GFNHDNMA_00364 1.3e-303 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GFNHDNMA_00365 4.7e-134 gmuR K UTRA
GFNHDNMA_00366 1.5e-50 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
GFNHDNMA_00367 1.6e-41
GFNHDNMA_00368 2.6e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
GFNHDNMA_00369 5.8e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GFNHDNMA_00370 2e-279 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GFNHDNMA_00371 1.9e-158 ypbG 2.7.1.2 GK ROK family
GFNHDNMA_00372 1.8e-116
GFNHDNMA_00374 3.5e-114 E Belongs to the SOS response-associated peptidase family
GFNHDNMA_00375 9.8e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
GFNHDNMA_00376 9.6e-91 comEB 3.5.4.12 F MafB19-like deaminase
GFNHDNMA_00377 4e-99 S TPM domain
GFNHDNMA_00378 1.2e-180 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
GFNHDNMA_00379 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFNHDNMA_00380 2.6e-146 tatD L hydrolase, TatD family
GFNHDNMA_00381 1.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GFNHDNMA_00382 6.1e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GFNHDNMA_00383 2.2e-35 veg S Biofilm formation stimulator VEG
GFNHDNMA_00384 1.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
GFNHDNMA_00385 7.2e-216 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFNHDNMA_00386 1.1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFNHDNMA_00387 1.2e-174 yvdE K helix_turn _helix lactose operon repressor
GFNHDNMA_00388 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
GFNHDNMA_00389 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
GFNHDNMA_00390 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
GFNHDNMA_00391 7.6e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
GFNHDNMA_00392 9.8e-208 msmX P Belongs to the ABC transporter superfamily
GFNHDNMA_00393 2.8e-216 malE G Bacterial extracellular solute-binding protein
GFNHDNMA_00394 3.6e-252 malF P Binding-protein-dependent transport system inner membrane component
GFNHDNMA_00395 1.6e-152 malG P ABC transporter permease
GFNHDNMA_00396 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
GFNHDNMA_00397 1.3e-265 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
GFNHDNMA_00398 6.2e-70 S Domain of unknown function (DUF1934)
GFNHDNMA_00399 5.5e-63 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GFNHDNMA_00400 2.2e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GFNHDNMA_00401 9.4e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFNHDNMA_00402 1.5e-231 pbuX F xanthine permease
GFNHDNMA_00403 2.6e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GFNHDNMA_00404 2.3e-123 K Psort location CytoplasmicMembrane, score
GFNHDNMA_00405 3.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GFNHDNMA_00406 0.0 2.1.1.72 V Type II restriction enzyme, methylase subunits
GFNHDNMA_00407 4.2e-12
GFNHDNMA_00408 6.2e-106 K transcriptional regulator
GFNHDNMA_00409 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
GFNHDNMA_00410 2.3e-109 K Helix-turn-helix
GFNHDNMA_00411 3.2e-112 1.6.5.2 S NADPH-dependent FMN reductase
GFNHDNMA_00412 7.3e-92 K Bacterial regulatory proteins, tetR family
GFNHDNMA_00413 8.8e-53 yjdF S Protein of unknown function (DUF2992)
GFNHDNMA_00414 1.8e-139 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GFNHDNMA_00415 5.5e-57 K PFAM helix-turn-helix- domain containing protein AraC type
GFNHDNMA_00416 4.7e-23 K Helix-turn-helix XRE-family like proteins
GFNHDNMA_00417 1.2e-08
GFNHDNMA_00418 9.7e-28 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFNHDNMA_00419 7.8e-200 ywhK S Membrane
GFNHDNMA_00420 2e-152 cylA V ABC transporter
GFNHDNMA_00421 1.4e-145 cylB V ABC-2 type transporter
GFNHDNMA_00422 1.6e-71 K LytTr DNA-binding domain
GFNHDNMA_00423 1.4e-63 S Protein of unknown function (DUF3021)
GFNHDNMA_00424 8.4e-82 XK27_09675 K Acetyltransferase (GNAT) domain
GFNHDNMA_00425 4.7e-177 1.1.1.1 C nadph quinone reductase
GFNHDNMA_00426 2.3e-78 K Transcriptional regulator
GFNHDNMA_00427 2.5e-83 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GFNHDNMA_00429 4e-95
GFNHDNMA_00430 4.1e-264 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GFNHDNMA_00431 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
GFNHDNMA_00432 2.6e-190 yfdV S Membrane transport protein
GFNHDNMA_00433 1.6e-39
GFNHDNMA_00435 2.2e-41 S Putative adhesin
GFNHDNMA_00436 2.1e-79
GFNHDNMA_00437 1.2e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GFNHDNMA_00438 5.3e-283 pipD E Dipeptidase
GFNHDNMA_00439 5.6e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GFNHDNMA_00440 1.9e-178 ABC-SBP S ABC transporter
GFNHDNMA_00441 3.5e-139 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
GFNHDNMA_00442 1.7e-134 XK27_08845 S ABC transporter, ATP-binding protein
GFNHDNMA_00443 3.5e-291 ybeC E amino acid
GFNHDNMA_00444 8e-41 rpmE2 J Ribosomal protein L31
GFNHDNMA_00445 7.2e-261 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GFNHDNMA_00446 5.5e-267 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GFNHDNMA_00447 5.9e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GFNHDNMA_00448 4.2e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GFNHDNMA_00449 3.5e-123 S (CBS) domain
GFNHDNMA_00450 3.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GFNHDNMA_00451 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GFNHDNMA_00452 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GFNHDNMA_00453 5.4e-34 yabO J S4 domain protein
GFNHDNMA_00454 4e-60 divIC D Septum formation initiator
GFNHDNMA_00455 1.2e-58 yabR J S1 RNA binding domain
GFNHDNMA_00456 2.7e-244 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GFNHDNMA_00457 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFNHDNMA_00458 0.0 S membrane
GFNHDNMA_00459 0.0 S membrane
GFNHDNMA_00460 2.7e-160 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GFNHDNMA_00461 3.4e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFNHDNMA_00462 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GFNHDNMA_00463 1.6e-08
GFNHDNMA_00465 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GFNHDNMA_00466 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GFNHDNMA_00467 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GFNHDNMA_00468 8e-96 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
GFNHDNMA_00469 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GFNHDNMA_00470 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GFNHDNMA_00471 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GFNHDNMA_00472 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
GFNHDNMA_00473 1.7e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GFNHDNMA_00474 1e-105 rplD J Forms part of the polypeptide exit tunnel
GFNHDNMA_00475 1.7e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GFNHDNMA_00476 1.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GFNHDNMA_00477 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GFNHDNMA_00478 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GFNHDNMA_00479 1.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GFNHDNMA_00480 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GFNHDNMA_00481 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
GFNHDNMA_00482 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GFNHDNMA_00483 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GFNHDNMA_00484 1.1e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GFNHDNMA_00485 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GFNHDNMA_00486 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GFNHDNMA_00487 2.1e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GFNHDNMA_00488 2.9e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GFNHDNMA_00489 1.5e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GFNHDNMA_00490 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GFNHDNMA_00491 1.4e-23 rpmD J Ribosomal protein L30
GFNHDNMA_00492 1.3e-70 rplO J Binds to the 23S rRNA
GFNHDNMA_00493 4.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GFNHDNMA_00494 4.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GFNHDNMA_00495 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GFNHDNMA_00496 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GFNHDNMA_00497 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GFNHDNMA_00498 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GFNHDNMA_00499 9.6e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GFNHDNMA_00500 7.4e-62 rplQ J Ribosomal protein L17
GFNHDNMA_00501 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GFNHDNMA_00502 9.8e-163 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GFNHDNMA_00503 1.8e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GFNHDNMA_00504 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GFNHDNMA_00505 5e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GFNHDNMA_00506 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
GFNHDNMA_00507 0.0 LV site-specific DNA-methyltransferase (adenine-specific) activity
GFNHDNMA_00508 1.1e-150 1.6.5.2 GM NmrA-like family
GFNHDNMA_00509 4.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
GFNHDNMA_00510 4.3e-129 pgm3 G Belongs to the phosphoglycerate mutase family
GFNHDNMA_00511 1e-51 K Transcriptional regulator, ArsR family
GFNHDNMA_00512 8.5e-154 czcD P cation diffusion facilitator family transporter
GFNHDNMA_00513 5.2e-35
GFNHDNMA_00514 9.9e-12
GFNHDNMA_00515 3.1e-124 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GFNHDNMA_00516 1.1e-183 S AAA domain
GFNHDNMA_00517 2.5e-15 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
GFNHDNMA_00522 2.4e-215 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GFNHDNMA_00523 2.7e-258 qacA EGP Major facilitator Superfamily
GFNHDNMA_00524 1.2e-115 3.6.1.27 I Acid phosphatase homologues
GFNHDNMA_00525 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GFNHDNMA_00526 5.6e-300 ytgP S Polysaccharide biosynthesis protein
GFNHDNMA_00527 1.4e-217 MA20_36090 S Protein of unknown function (DUF2974)
GFNHDNMA_00528 1e-136
GFNHDNMA_00529 8.7e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GFNHDNMA_00530 5.2e-170 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GFNHDNMA_00531 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GFNHDNMA_00532 1.9e-172 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
GFNHDNMA_00533 2.7e-46
GFNHDNMA_00534 2.1e-277 K Sigma-54 interaction domain
GFNHDNMA_00535 1.1e-76 K Sigma-54 interaction domain
GFNHDNMA_00536 2.5e-55 2.7.1.191 G PTS system fructose IIA component
GFNHDNMA_00537 7e-81 ptsB 2.7.1.191 G PTS system sorbose subfamily IIB component
GFNHDNMA_00538 6.2e-138 ptsC G PTS system sorbose-specific iic component
GFNHDNMA_00539 4.5e-149 ptsD G PTS system mannose/fructose/sorbose family IID component
GFNHDNMA_00540 2.6e-113 mgtC S MgtC family
GFNHDNMA_00541 1.3e-134 K Sigma-54 factor, core binding domain
GFNHDNMA_00543 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GFNHDNMA_00544 8.8e-119 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
GFNHDNMA_00545 1.1e-105 ylbE GM NAD(P)H-binding
GFNHDNMA_00546 4.2e-80 yebR 1.8.4.14 T GAF domain-containing protein
GFNHDNMA_00547 2.1e-219 yfeO P Voltage gated chloride channel
GFNHDNMA_00548 1.5e-191 S Bacteriocin helveticin-J
GFNHDNMA_00549 7e-101 tag 3.2.2.20 L glycosylase
GFNHDNMA_00550 1.1e-162 mleP3 S Membrane transport protein
GFNHDNMA_00551 2.4e-136 S CAAX amino terminal protease
GFNHDNMA_00552 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GFNHDNMA_00553 6e-253 emrY EGP Major facilitator Superfamily
GFNHDNMA_00554 1.4e-259 emrY EGP Major facilitator Superfamily
GFNHDNMA_00555 3.4e-76 2.3.1.128 K acetyltransferase
GFNHDNMA_00556 1.6e-208 L Putative transposase DNA-binding domain
GFNHDNMA_00557 8.4e-145 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GFNHDNMA_00558 1.3e-101 yagU S Protein of unknown function (DUF1440)
GFNHDNMA_00559 1.7e-145 S hydrolase
GFNHDNMA_00560 6.7e-43 K Transcriptional regulator
GFNHDNMA_00561 2.7e-103 K Transcriptional regulator
GFNHDNMA_00562 5.6e-242 pyrP F Permease
GFNHDNMA_00563 6e-132 lacR K DeoR C terminal sensor domain
GFNHDNMA_00564 5.1e-72 lacA 5.3.1.26 G Ribose/Galactose Isomerase
GFNHDNMA_00565 4.7e-105 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
GFNHDNMA_00566 4.3e-131 lacT K CAT RNA binding domain
GFNHDNMA_00567 6.9e-54 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
GFNHDNMA_00568 2.6e-300 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
GFNHDNMA_00569 4e-278 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
GFNHDNMA_00570 2.6e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
GFNHDNMA_00571 2.8e-111 3.6.1.27 I Acid phosphatase homologues
GFNHDNMA_00572 1.9e-282 E Phospholipase B
GFNHDNMA_00573 3.6e-265 pepC 3.4.22.40 E Peptidase C1-like family
GFNHDNMA_00574 9.7e-284 gadC E Contains amino acid permease domain
GFNHDNMA_00575 2e-274 pipD E Peptidase family C69
GFNHDNMA_00576 1.2e-263 pepC 3.4.22.40 E Peptidase C1-like family
GFNHDNMA_00577 3.3e-308 gadC E Contains amino acid permease domain
GFNHDNMA_00578 1.3e-249 yagE E amino acid
GFNHDNMA_00579 2.8e-216 mdtG EGP Major facilitator Superfamily
GFNHDNMA_00580 2.2e-31
GFNHDNMA_00581 5.1e-69 K helix_turn_helix multiple antibiotic resistance protein
GFNHDNMA_00582 1e-39
GFNHDNMA_00583 8.2e-76 K Bacterial regulatory proteins, tetR family
GFNHDNMA_00584 2.1e-185 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GFNHDNMA_00585 7.3e-126 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
GFNHDNMA_00586 5.1e-209 pepA E M42 glutamyl aminopeptidase
GFNHDNMA_00588 5e-111 ybbL S ABC transporter, ATP-binding protein
GFNHDNMA_00589 1.5e-127 ybbM S Uncharacterised protein family (UPF0014)
GFNHDNMA_00590 9.8e-260 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
GFNHDNMA_00591 3.7e-268 aaxC E Arginine ornithine antiporter
GFNHDNMA_00592 5.6e-255 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
GFNHDNMA_00593 0.0 lacA 3.2.1.23 G -beta-galactosidase
GFNHDNMA_00594 4.3e-283 dtpT U amino acid peptide transporter
GFNHDNMA_00595 1.6e-279 pipD E Peptidase family C69
GFNHDNMA_00596 1.1e-218 naiP EGP Major facilitator Superfamily
GFNHDNMA_00597 1.1e-155 S Alpha beta hydrolase
GFNHDNMA_00598 3.9e-67 K Transcriptional regulator, MarR family
GFNHDNMA_00599 2.9e-299 XK27_09600 V ABC transporter, ATP-binding protein
GFNHDNMA_00600 0.0 V ABC transporter transmembrane region
GFNHDNMA_00601 3.8e-148 glnH ET ABC transporter
GFNHDNMA_00602 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GFNHDNMA_00603 6.9e-150 glnH ET ABC transporter
GFNHDNMA_00604 2.4e-110 gluC P ABC transporter permease
GFNHDNMA_00605 5.7e-107 glnP P ABC transporter permease
GFNHDNMA_00606 1.9e-65
GFNHDNMA_00607 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
GFNHDNMA_00608 7e-130 treR K UTRA
GFNHDNMA_00609 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GFNHDNMA_00610 6.4e-76 S Putative adhesin
GFNHDNMA_00612 8.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
GFNHDNMA_00614 3.5e-225 2.7.13.3 T GHKL domain
GFNHDNMA_00615 2.6e-133 K LytTr DNA-binding domain
GFNHDNMA_00616 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GFNHDNMA_00617 4.9e-97 M Transport protein ComB
GFNHDNMA_00619 1.3e-45 S Enterocin A Immunity
GFNHDNMA_00623 1.8e-53 S Enterocin A Immunity
GFNHDNMA_00625 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
GFNHDNMA_00626 5.5e-158 rssA S Phospholipase, patatin family
GFNHDNMA_00627 2.5e-254 glnPH2 P ABC transporter permease
GFNHDNMA_00628 1.2e-129 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
GFNHDNMA_00629 2.8e-96 K Acetyltransferase (GNAT) domain
GFNHDNMA_00630 2.1e-160 pstS P Phosphate
GFNHDNMA_00631 1.2e-161 pstC P probably responsible for the translocation of the substrate across the membrane
GFNHDNMA_00632 2.4e-156 pstA P Phosphate transport system permease protein PstA
GFNHDNMA_00633 6.3e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GFNHDNMA_00634 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GFNHDNMA_00635 1.9e-108 phoU P Plays a role in the regulation of phosphate uptake
GFNHDNMA_00636 2.8e-60 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GFNHDNMA_00637 5.1e-279 S C4-dicarboxylate anaerobic carrier
GFNHDNMA_00638 2.6e-85 dps P Belongs to the Dps family
GFNHDNMA_00639 1.3e-157 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFNHDNMA_00640 4.1e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GFNHDNMA_00641 3.5e-53
GFNHDNMA_00642 1.1e-36 KLT Lanthionine synthetase C-like protein
GFNHDNMA_00643 3.5e-11 KLT Lanthionine synthetase C-like protein
GFNHDNMA_00645 1.9e-188 V ABC transporter transmembrane region
GFNHDNMA_00646 5.9e-174 rihB 3.2.2.1 F Nucleoside
GFNHDNMA_00647 8.9e-133 gntR K UbiC transcription regulator-associated domain protein
GFNHDNMA_00648 7e-53 S Enterocin A Immunity
GFNHDNMA_00649 1.1e-136 glcR K DeoR C terminal sensor domain
GFNHDNMA_00650 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
GFNHDNMA_00651 7.3e-118 C nitroreductase
GFNHDNMA_00652 3.9e-130
GFNHDNMA_00653 1.1e-237 yhdP S Transporter associated domain
GFNHDNMA_00654 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GFNHDNMA_00655 8e-233 potE E amino acid
GFNHDNMA_00656 5.8e-137 M Glycosyl hydrolases family 25
GFNHDNMA_00657 3.5e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
GFNHDNMA_00658 1.1e-250 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GFNHDNMA_00661 5.5e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GFNHDNMA_00662 4.2e-89 gtcA S Teichoic acid glycosylation protein
GFNHDNMA_00663 2.5e-77 fld C Flavodoxin
GFNHDNMA_00664 1.9e-160 map 3.4.11.18 E Methionine Aminopeptidase
GFNHDNMA_00665 1.1e-161 yihY S Belongs to the UPF0761 family
GFNHDNMA_00666 1.2e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GFNHDNMA_00667 4.4e-180 E ABC transporter, ATP-binding protein
GFNHDNMA_00668 1.3e-285 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GFNHDNMA_00669 1.1e-66 O OsmC-like protein
GFNHDNMA_00670 1.1e-112 2.7.6.5 T Region found in RelA / SpoT proteins
GFNHDNMA_00671 1.2e-115 K response regulator
GFNHDNMA_00672 3e-224 sptS 2.7.13.3 T Histidine kinase
GFNHDNMA_00673 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GFNHDNMA_00674 0.0 pepN 3.4.11.2 E aminopeptidase
GFNHDNMA_00675 1e-142 S haloacid dehalogenase-like hydrolase
GFNHDNMA_00677 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GFNHDNMA_00678 1.8e-69
GFNHDNMA_00679 3.2e-107 fic D Fic/DOC family
GFNHDNMA_00680 2.5e-141 ppm1 GT2 M Glycosyl transferase family 2
GFNHDNMA_00681 2.4e-93 S Domain of unknown function (DUF4811)
GFNHDNMA_00682 2.3e-265 lmrB EGP Major facilitator Superfamily
GFNHDNMA_00683 1.9e-77 K MerR HTH family regulatory protein
GFNHDNMA_00684 0.0 oppA E ABC transporter substrate-binding protein
GFNHDNMA_00685 6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
GFNHDNMA_00686 1.6e-295 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GFNHDNMA_00687 8.4e-162 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GFNHDNMA_00688 2.6e-30 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
GFNHDNMA_00689 3e-87 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
GFNHDNMA_00690 1e-220 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
GFNHDNMA_00691 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GFNHDNMA_00692 1.4e-195 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
GFNHDNMA_00693 2.1e-249 pepC 3.4.22.40 E Peptidase C1-like family
GFNHDNMA_00695 6.5e-19 K Transcriptional regulator, TetR family
GFNHDNMA_00696 3.5e-48 K Transcriptional regulator, TetR family
GFNHDNMA_00698 6.4e-69 3.4.22.70 M Sortase family
GFNHDNMA_00699 0.0 UW LPXTG-motif cell wall anchor domain protein
GFNHDNMA_00700 0.0 infB UW LPXTG-motif cell wall anchor domain protein
GFNHDNMA_00701 1.1e-150 M domain protein
GFNHDNMA_00702 5.1e-171 I Carboxylesterase family
GFNHDNMA_00703 5e-311 S Predicted membrane protein (DUF2207)
GFNHDNMA_00704 7.5e-123 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GFNHDNMA_00705 2e-52
GFNHDNMA_00706 1.2e-144 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
GFNHDNMA_00707 2.9e-91 S ECF-type riboflavin transporter, S component
GFNHDNMA_00708 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GFNHDNMA_00709 4.1e-63
GFNHDNMA_00710 3.5e-12
GFNHDNMA_00711 1.1e-213 S Uncharacterized protein conserved in bacteria (DUF2325)
GFNHDNMA_00712 6.4e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GFNHDNMA_00713 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
GFNHDNMA_00714 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
GFNHDNMA_00715 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GFNHDNMA_00716 6.4e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GFNHDNMA_00717 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GFNHDNMA_00718 8.2e-73 yqhY S Asp23 family, cell envelope-related function
GFNHDNMA_00719 3.6e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GFNHDNMA_00720 6.5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GFNHDNMA_00721 2.6e-250 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GFNHDNMA_00722 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GFNHDNMA_00723 1.6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GFNHDNMA_00724 1.1e-155 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GFNHDNMA_00725 1e-293 recN L May be involved in recombinational repair of damaged DNA
GFNHDNMA_00726 3.8e-36
GFNHDNMA_00728 1.1e-196 V ABC-type multidrug transport system, ATPase and permease components
GFNHDNMA_00729 2.4e-183 V ABC-type multidrug transport system, ATPase and permease components
GFNHDNMA_00730 1.1e-89 ymdB S Macro domain protein
GFNHDNMA_00731 1.3e-296 V ABC transporter transmembrane region
GFNHDNMA_00732 4.9e-125 puuD S peptidase C26
GFNHDNMA_00733 2.5e-217 mdtG EGP Major facilitator Superfamily
GFNHDNMA_00734 4.6e-152
GFNHDNMA_00735 4.3e-71 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
GFNHDNMA_00736 3e-155 2.7.7.12 C Domain of unknown function (DUF4931)
GFNHDNMA_00737 3.1e-153 ybbH_2 K Helix-turn-helix domain, rpiR family
GFNHDNMA_00738 3.6e-137 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
GFNHDNMA_00739 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
GFNHDNMA_00740 2.5e-95 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFNHDNMA_00741 8.7e-50 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GFNHDNMA_00742 3.1e-127
GFNHDNMA_00743 8.5e-52
GFNHDNMA_00744 3e-139 S Belongs to the UPF0246 family
GFNHDNMA_00745 2.3e-136 aroD S Alpha/beta hydrolase family
GFNHDNMA_00746 3.6e-114 G Phosphoglycerate mutase family
GFNHDNMA_00747 4.6e-111 G phosphoglycerate mutase
GFNHDNMA_00748 2.4e-92 ygfC K Bacterial regulatory proteins, tetR family
GFNHDNMA_00749 3.3e-181 hrtB V ABC transporter permease
GFNHDNMA_00750 5.2e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
GFNHDNMA_00751 1.7e-31 K CAT RNA binding domain
GFNHDNMA_00752 2.3e-110 K CAT RNA binding domain
GFNHDNMA_00753 0.0 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GFNHDNMA_00754 4.1e-294 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GFNHDNMA_00755 2.5e-272 pipD E Dipeptidase
GFNHDNMA_00756 1e-37
GFNHDNMA_00757 5e-108 K WHG domain
GFNHDNMA_00758 2.2e-96 nqr 1.5.1.36 S reductase
GFNHDNMA_00759 3.7e-99 azr 1.5.1.36 S NADPH-dependent FMN reductase
GFNHDNMA_00760 3.7e-201 4.2.1.126 S Bacterial protein of unknown function (DUF871)
GFNHDNMA_00761 1.3e-148 3.1.3.48 T Tyrosine phosphatase family
GFNHDNMA_00762 2.1e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GFNHDNMA_00763 6.4e-96 cvpA S Colicin V production protein
GFNHDNMA_00764 2.8e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
GFNHDNMA_00765 2.2e-154 noc K Belongs to the ParB family
GFNHDNMA_00766 3.3e-138 soj D Sporulation initiation inhibitor
GFNHDNMA_00767 6.5e-154 spo0J K Belongs to the ParB family
GFNHDNMA_00768 2.9e-43 yyzM S Bacterial protein of unknown function (DUF951)
GFNHDNMA_00769 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GFNHDNMA_00770 1.6e-149 XK27_01040 S Protein of unknown function (DUF1129)
GFNHDNMA_00771 7.1e-298 V ABC transporter, ATP-binding protein
GFNHDNMA_00772 0.0 V ABC transporter
GFNHDNMA_00773 7.4e-121 K response regulator
GFNHDNMA_00774 1.2e-200 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
GFNHDNMA_00775 7.7e-307 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GFNHDNMA_00776 1.3e-142 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GFNHDNMA_00777 3.7e-165 natA S ABC transporter, ATP-binding protein
GFNHDNMA_00778 1.5e-220 natB CP ABC-2 family transporter protein
GFNHDNMA_00779 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
GFNHDNMA_00780 2.4e-136 fruR K DeoR C terminal sensor domain
GFNHDNMA_00781 1.2e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GFNHDNMA_00782 0.0 fruA 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
GFNHDNMA_00783 0.0 2.7.7.7 M domain protein
GFNHDNMA_00784 4.7e-140 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
GFNHDNMA_00785 1.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
GFNHDNMA_00786 1.6e-152 psaA P Belongs to the bacterial solute-binding protein 9 family
GFNHDNMA_00787 1.4e-116 fhuC P ABC transporter
GFNHDNMA_00788 4.3e-133 znuB U ABC 3 transport family
GFNHDNMA_00789 7e-257 lctP C L-lactate permease
GFNHDNMA_00790 0.0 pepF E oligoendopeptidase F
GFNHDNMA_00791 1.4e-209 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GFNHDNMA_00792 4.8e-39
GFNHDNMA_00793 4.3e-62
GFNHDNMA_00794 9e-284 S ABC transporter
GFNHDNMA_00795 1.1e-136 thrE S Putative threonine/serine exporter
GFNHDNMA_00796 2.8e-79 S Threonine/Serine exporter, ThrE
GFNHDNMA_00797 8.9e-40
GFNHDNMA_00798 4.7e-60 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
GFNHDNMA_00799 2.6e-80
GFNHDNMA_00800 1.7e-96 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFNHDNMA_00801 1.5e-38 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFNHDNMA_00802 1.5e-80 nrdI F Belongs to the NrdI family
GFNHDNMA_00803 5.3e-110
GFNHDNMA_00804 2.1e-264 S O-antigen ligase like membrane protein
GFNHDNMA_00805 5.3e-44
GFNHDNMA_00806 1.4e-98 gmk2 2.7.4.8 F Guanylate kinase
GFNHDNMA_00807 6e-116 M NlpC P60 family protein
GFNHDNMA_00808 1.2e-230 S Putative peptidoglycan binding domain
GFNHDNMA_00809 9.8e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFNHDNMA_00810 8.4e-276 E amino acid
GFNHDNMA_00811 2.4e-133 cysA V ABC transporter, ATP-binding protein
GFNHDNMA_00812 0.0 V FtsX-like permease family
GFNHDNMA_00813 3.9e-124 pgm3 G Phosphoglycerate mutase family
GFNHDNMA_00814 1.6e-26
GFNHDNMA_00815 8.1e-52
GFNHDNMA_00816 1.9e-149 xth 3.1.11.2 L exodeoxyribonuclease III
GFNHDNMA_00817 9.4e-10 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
GFNHDNMA_00818 0.0 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
GFNHDNMA_00819 9e-127 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GFNHDNMA_00820 9.6e-144 rpiR1 K Helix-turn-helix domain, rpiR family
GFNHDNMA_00821 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
GFNHDNMA_00823 5.1e-116 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
GFNHDNMA_00824 0.0 helD 3.6.4.12 L DNA helicase
GFNHDNMA_00825 3.1e-122 yvpB S Peptidase_C39 like family
GFNHDNMA_00826 1.6e-105 E GDSL-like Lipase/Acylhydrolase
GFNHDNMA_00827 1.9e-163 coaA 2.7.1.33 F Pantothenic acid kinase
GFNHDNMA_00828 2.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GFNHDNMA_00829 0.0 fhaB M Rib/alpha-like repeat
GFNHDNMA_00830 0.0 fhaB M Rib/alpha-like repeat
GFNHDNMA_00831 2.4e-142 licT K CAT RNA binding domain
GFNHDNMA_00832 0.0 bglP 2.7.1.211 G phosphotransferase system
GFNHDNMA_00833 2.8e-271 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GFNHDNMA_00834 7.2e-156 EG EamA-like transporter family
GFNHDNMA_00835 0.0 oppA E ABC transporter substrate-binding protein
GFNHDNMA_00836 1.2e-166 2.7.1.191 G PTS system sorbose subfamily IIB component
GFNHDNMA_00837 4.1e-139 G PTS system sorbose-specific iic component
GFNHDNMA_00838 1.6e-143 G PTS system mannose/fructose/sorbose family IID component
GFNHDNMA_00839 3.4e-62
GFNHDNMA_00840 1.4e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GFNHDNMA_00841 8.6e-204 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
GFNHDNMA_00842 2.1e-236 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GFNHDNMA_00843 6.2e-134 S PAS domain
GFNHDNMA_00844 1.1e-272 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
GFNHDNMA_00845 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
GFNHDNMA_00846 8.6e-145 glvR K Helix-turn-helix domain, rpiR family
GFNHDNMA_00847 1.6e-80
GFNHDNMA_00848 1.2e-85 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GFNHDNMA_00849 9.8e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GFNHDNMA_00850 0.0 GM domain, Protein
GFNHDNMA_00851 5.3e-144 pnuC H nicotinamide mononucleotide transporter
GFNHDNMA_00852 2.1e-91 S PAS domain
GFNHDNMA_00853 3.1e-242 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GFNHDNMA_00854 2e-74 S Protein of unknown function (DUF3290)
GFNHDNMA_00855 5.8e-112 yviA S Protein of unknown function (DUF421)
GFNHDNMA_00856 3.3e-149 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GFNHDNMA_00857 2.5e-183 dnaQ 2.7.7.7 L EXOIII
GFNHDNMA_00858 2.7e-197 ltrA S Bacterial low temperature requirement A protein (LtrA)
GFNHDNMA_00859 7.6e-157 dkg S reductase
GFNHDNMA_00860 6e-157 endA F DNA RNA non-specific endonuclease
GFNHDNMA_00861 3.9e-281 pipD E Dipeptidase
GFNHDNMA_00862 3.8e-204 malK P ATPases associated with a variety of cellular activities
GFNHDNMA_00863 2.1e-157 gtsB P ABC-type sugar transport systems, permease components
GFNHDNMA_00864 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
GFNHDNMA_00865 3.3e-247 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
GFNHDNMA_00866 2.5e-239 G Bacterial extracellular solute-binding protein
GFNHDNMA_00867 2.9e-39 ypaA S Protein of unknown function (DUF1304)
GFNHDNMA_00868 1.7e-76 yybA 2.3.1.57 K Transcriptional regulator
GFNHDNMA_00869 4.1e-87 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
GFNHDNMA_00870 2.6e-79 yjcF S Acetyltransferase (GNAT) domain
GFNHDNMA_00871 2e-166 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
GFNHDNMA_00872 3.8e-160 3.5.2.6 V Beta-lactamase enzyme family
GFNHDNMA_00873 3.9e-96 yobS K Bacterial regulatory proteins, tetR family
GFNHDNMA_00874 0.0 ydgH S MMPL family
GFNHDNMA_00875 1.2e-141 cof S haloacid dehalogenase-like hydrolase
GFNHDNMA_00876 5.8e-126 S SNARE associated Golgi protein
GFNHDNMA_00877 1.9e-178
GFNHDNMA_00878 1.4e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
GFNHDNMA_00879 1.3e-156 hipB K Helix-turn-helix
GFNHDNMA_00880 6.3e-156 I alpha/beta hydrolase fold
GFNHDNMA_00881 5.3e-107 yjbF S SNARE associated Golgi protein
GFNHDNMA_00882 2.3e-101 J Acetyltransferase (GNAT) domain
GFNHDNMA_00883 2.5e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GFNHDNMA_00884 1.1e-281 manR K PRD domain
GFNHDNMA_00885 1.7e-61 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GFNHDNMA_00886 8.3e-76 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GFNHDNMA_00887 4.2e-245 G PTS system sugar-specific permease component
GFNHDNMA_00888 8e-45 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
GFNHDNMA_00889 2.6e-78 3.6.1.55 L NUDIX domain
GFNHDNMA_00890 1.6e-08 GH23 S M26 IgA1-specific Metallo-endopeptidase C-terminal region
GFNHDNMA_00891 0.0 GH23 S M26 IgA1-specific Metallo-endopeptidase C-terminal region
GFNHDNMA_00893 1e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GFNHDNMA_00894 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GFNHDNMA_00895 1.4e-46 yheA S Belongs to the UPF0342 family
GFNHDNMA_00896 9.8e-217 yhaO L Ser Thr phosphatase family protein
GFNHDNMA_00897 0.0 L AAA domain
GFNHDNMA_00898 3e-184 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
GFNHDNMA_00899 4.9e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GFNHDNMA_00900 9.5e-24 S YtxH-like protein
GFNHDNMA_00901 5.2e-52
GFNHDNMA_00902 9.2e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
GFNHDNMA_00903 1.7e-134 ecsA V ABC transporter, ATP-binding protein
GFNHDNMA_00904 2.1e-224 ecsB U ABC transporter
GFNHDNMA_00905 3.1e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GFNHDNMA_00906 2.1e-61
GFNHDNMA_00907 4.7e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GFNHDNMA_00908 4.1e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GFNHDNMA_00909 5.5e-86 cutC P Participates in the control of copper homeostasis
GFNHDNMA_00910 4.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GFNHDNMA_00911 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GFNHDNMA_00912 5.7e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GFNHDNMA_00913 5.6e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GFNHDNMA_00914 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GFNHDNMA_00915 2.5e-237 dnaB L Replication initiation and membrane attachment
GFNHDNMA_00916 5.4e-156 dnaI L Primosomal protein DnaI
GFNHDNMA_00917 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GFNHDNMA_00918 1.1e-74 K LytTr DNA-binding domain
GFNHDNMA_00919 1.6e-73 S Protein of unknown function (DUF3021)
GFNHDNMA_00920 8.1e-235 S CAAX protease self-immunity
GFNHDNMA_00921 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GFNHDNMA_00922 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GFNHDNMA_00923 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GFNHDNMA_00924 2.6e-167 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFNHDNMA_00925 7.3e-89 yqeG S HAD phosphatase, family IIIA
GFNHDNMA_00926 1.8e-209 yqeH S Ribosome biogenesis GTPase YqeH
GFNHDNMA_00927 5.3e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GFNHDNMA_00928 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
GFNHDNMA_00929 3.7e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GFNHDNMA_00930 1.5e-214 ylbM S Belongs to the UPF0348 family
GFNHDNMA_00931 1.3e-91 yceD S Uncharacterized ACR, COG1399
GFNHDNMA_00932 1.1e-130 K response regulator
GFNHDNMA_00933 1e-279 arlS 2.7.13.3 T Histidine kinase
GFNHDNMA_00934 4.7e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GFNHDNMA_00935 1.5e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GFNHDNMA_00936 4e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFNHDNMA_00937 6.2e-63 yodB K Transcriptional regulator, HxlR family
GFNHDNMA_00938 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GFNHDNMA_00939 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GFNHDNMA_00940 3.2e-203 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GFNHDNMA_00941 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GFNHDNMA_00942 0.0 S membrane
GFNHDNMA_00943 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
GFNHDNMA_00944 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GFNHDNMA_00945 4.9e-91 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GFNHDNMA_00946 4e-119 gluP 3.4.21.105 S Rhomboid family
GFNHDNMA_00947 7.9e-35 yqgQ S Bacterial protein of unknown function (DUF910)
GFNHDNMA_00948 5.1e-58 yqhL P Rhodanese-like protein
GFNHDNMA_00949 8.1e-19 S Protein of unknown function (DUF3042)
GFNHDNMA_00950 4.4e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GFNHDNMA_00951 7.1e-261 glnA 6.3.1.2 E glutamine synthetase
GFNHDNMA_00952 1.1e-206 EGP Major facilitator Superfamily
GFNHDNMA_00953 9.5e-152 S haloacid dehalogenase-like hydrolase
GFNHDNMA_00955 5.3e-178 D Alpha beta
GFNHDNMA_00956 3.2e-217 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
GFNHDNMA_00957 1.9e-220 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GFNHDNMA_00958 8.4e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
GFNHDNMA_00959 3.9e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFNHDNMA_00960 4.6e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
GFNHDNMA_00961 2.4e-112 ygaC J Belongs to the UPF0374 family
GFNHDNMA_00962 7e-89
GFNHDNMA_00963 8.8e-78
GFNHDNMA_00964 3.6e-157 hlyX S Transporter associated domain
GFNHDNMA_00965 3.3e-302 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GFNHDNMA_00966 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
GFNHDNMA_00967 0.0 clpE O Belongs to the ClpA ClpB family
GFNHDNMA_00968 5.9e-25
GFNHDNMA_00969 4.2e-40 ptsH G phosphocarrier protein HPR
GFNHDNMA_00970 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GFNHDNMA_00971 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GFNHDNMA_00972 2.1e-117 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GFNHDNMA_00973 2.7e-158 coiA 3.6.4.12 S Competence protein
GFNHDNMA_00974 1.4e-107 yjbH Q Thioredoxin
GFNHDNMA_00975 1.1e-110 yjbK S CYTH
GFNHDNMA_00976 5.2e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
GFNHDNMA_00977 2.5e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GFNHDNMA_00978 1.1e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GFNHDNMA_00979 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
GFNHDNMA_00980 7.9e-25 N Uncharacterized conserved protein (DUF2075)
GFNHDNMA_00981 2.1e-168 N Uncharacterized conserved protein (DUF2075)
GFNHDNMA_00982 1.2e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
GFNHDNMA_00983 4.9e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
GFNHDNMA_00984 1.5e-209 yubA S AI-2E family transporter
GFNHDNMA_00985 4.6e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GFNHDNMA_00986 1.7e-75 WQ51_03320 S Protein of unknown function (DUF1149)
GFNHDNMA_00987 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GFNHDNMA_00988 5e-229 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
GFNHDNMA_00989 1.8e-231 S Peptidase M16
GFNHDNMA_00990 1.1e-130 IQ Enoyl-(Acyl carrier protein) reductase
GFNHDNMA_00991 9.8e-125 ymfM S Helix-turn-helix domain
GFNHDNMA_00992 3e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFNHDNMA_00993 3.5e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GFNHDNMA_00994 6.9e-194 rny S Endoribonuclease that initiates mRNA decay
GFNHDNMA_00995 1.6e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
GFNHDNMA_00996 4.3e-118 yvyE 3.4.13.9 S YigZ family
GFNHDNMA_00997 1.6e-224 comFA L Helicase C-terminal domain protein
GFNHDNMA_00998 6.7e-127 comFC S Competence protein
GFNHDNMA_00999 1.3e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GFNHDNMA_01000 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GFNHDNMA_01001 3.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GFNHDNMA_01002 7.6e-24
GFNHDNMA_01003 4.7e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GFNHDNMA_01004 1.2e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GFNHDNMA_01005 1.3e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GFNHDNMA_01006 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GFNHDNMA_01007 1.7e-155 lacR K Transcriptional regulator
GFNHDNMA_01008 1.4e-201 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GFNHDNMA_01009 7e-254 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GFNHDNMA_01010 6.1e-161 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GFNHDNMA_01011 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GFNHDNMA_01012 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GFNHDNMA_01013 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GFNHDNMA_01014 8.1e-91 S Short repeat of unknown function (DUF308)
GFNHDNMA_01015 3.5e-160 rapZ S Displays ATPase and GTPase activities
GFNHDNMA_01016 1.7e-193 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GFNHDNMA_01017 6.2e-171 whiA K May be required for sporulation
GFNHDNMA_01018 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GFNHDNMA_01019 4.5e-277 ycaM E amino acid
GFNHDNMA_01021 1.4e-187 cggR K Putative sugar-binding domain
GFNHDNMA_01022 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GFNHDNMA_01023 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GFNHDNMA_01024 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GFNHDNMA_01025 4e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GFNHDNMA_01026 1.9e-28 secG U Preprotein translocase
GFNHDNMA_01027 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GFNHDNMA_01028 1.1e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GFNHDNMA_01029 2.3e-104 3.2.2.20 K acetyltransferase
GFNHDNMA_01030 9.2e-77
GFNHDNMA_01031 5.8e-94
GFNHDNMA_01032 7.5e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
GFNHDNMA_01033 2.4e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GFNHDNMA_01034 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GFNHDNMA_01035 2.2e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
GFNHDNMA_01036 1.2e-99 dnaQ 2.7.7.7 L DNA polymerase III
GFNHDNMA_01037 5.8e-166 murB 1.3.1.98 M Cell wall formation
GFNHDNMA_01038 2.1e-202 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GFNHDNMA_01039 2.3e-129 potB P ABC transporter permease
GFNHDNMA_01040 2.9e-137 potC P ABC transporter permease
GFNHDNMA_01041 1.3e-209 potD P ABC transporter
GFNHDNMA_01042 1.3e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GFNHDNMA_01043 4.9e-171 ybbR S YbbR-like protein
GFNHDNMA_01044 4.5e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFNHDNMA_01045 1.7e-148 S Sucrose-6F-phosphate phosphohydrolase
GFNHDNMA_01046 6.5e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GFNHDNMA_01047 7.6e-61 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GFNHDNMA_01048 3.6e-195 S Putative adhesin
GFNHDNMA_01049 2e-113
GFNHDNMA_01050 1.5e-146 yisY 1.11.1.10 S Alpha/beta hydrolase family
GFNHDNMA_01051 1.8e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
GFNHDNMA_01052 5.8e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GFNHDNMA_01053 4e-95 S VanZ like family
GFNHDNMA_01054 1.5e-132 yebC K Transcriptional regulatory protein
GFNHDNMA_01055 1.3e-179 comGA NU Type II IV secretion system protein
GFNHDNMA_01056 1.6e-172 comGB NU type II secretion system
GFNHDNMA_01057 1.2e-40 comGC U Required for transformation and DNA binding
GFNHDNMA_01058 1.4e-58
GFNHDNMA_01059 1.7e-10
GFNHDNMA_01060 4e-84 comGF U Putative Competence protein ComGF
GFNHDNMA_01061 5.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
GFNHDNMA_01062 1e-226 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GFNHDNMA_01064 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GFNHDNMA_01065 6.2e-246 hisS 6.1.1.21 J histidyl-tRNA synthetase
GFNHDNMA_01066 9.6e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GFNHDNMA_01067 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFNHDNMA_01068 2.4e-65
GFNHDNMA_01069 1.6e-171 prmA J Ribosomal protein L11 methyltransferase
GFNHDNMA_01070 5.3e-68 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GFNHDNMA_01071 2.4e-290 S Bacterial membrane protein, YfhO
GFNHDNMA_01072 2.6e-308 S Bacterial membrane protein, YfhO
GFNHDNMA_01073 0.0 aha1 P E1-E2 ATPase
GFNHDNMA_01074 1.1e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
GFNHDNMA_01075 1.1e-243 yjjP S Putative threonine/serine exporter
GFNHDNMA_01076 7.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GFNHDNMA_01077 6.1e-260 frdC 1.3.5.4 C FAD binding domain
GFNHDNMA_01078 4.5e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GFNHDNMA_01079 1.4e-66 metI P ABC transporter permease
GFNHDNMA_01080 8.4e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFNHDNMA_01081 6.7e-156 metQ1 P Belongs to the nlpA lipoprotein family
GFNHDNMA_01082 7.2e-55 L nuclease
GFNHDNMA_01083 9.7e-139 F DNA/RNA non-specific endonuclease
GFNHDNMA_01084 2.3e-48 K Helix-turn-helix domain
GFNHDNMA_01085 3.3e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GFNHDNMA_01086 1.5e-305 ybiT S ABC transporter, ATP-binding protein
GFNHDNMA_01087 3.1e-17 S Sugar efflux transporter for intercellular exchange
GFNHDNMA_01088 6.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GFNHDNMA_01089 2.2e-102 3.6.1.27 I Acid phosphatase homologues
GFNHDNMA_01090 1.1e-106 lysA2 M Glycosyl hydrolases family 25
GFNHDNMA_01092 4.1e-32
GFNHDNMA_01093 2e-57
GFNHDNMA_01094 4.9e-33
GFNHDNMA_01096 4.5e-212 GT2,GT4 LM gp58-like protein
GFNHDNMA_01097 2.4e-54 S Phage tail protein
GFNHDNMA_01098 1.2e-121 Z012_10445 D Phage tail tape measure protein
GFNHDNMA_01099 2.5e-24
GFNHDNMA_01100 4.2e-21 S Pfam:Phage_TAC_12
GFNHDNMA_01101 3.7e-73 S Phage major tail protein 2
GFNHDNMA_01102 6.8e-15 S Protein of unknown function (DUF3168)
GFNHDNMA_01103 2.5e-23 S Bacteriophage HK97-gp10, putative tail-component
GFNHDNMA_01104 1.6e-25
GFNHDNMA_01105 1.5e-29 S Phage gp6-like head-tail connector protein
GFNHDNMA_01106 4.4e-86
GFNHDNMA_01107 4.3e-26 S Domain of unknown function (DUF4355)
GFNHDNMA_01108 1.7e-24
GFNHDNMA_01109 4.7e-114 S head morphogenesis protein, SPP1 gp7 family
GFNHDNMA_01110 1.7e-108 S Phage portal protein, SPP1 Gp6-like
GFNHDNMA_01111 1.5e-212 S Phage terminase, large subunit
GFNHDNMA_01113 8.9e-56 L Terminase small subunit
GFNHDNMA_01115 3.4e-50 arpU S Phage transcriptional regulator, ArpU family
GFNHDNMA_01117 8.8e-51 S VRR_NUC
GFNHDNMA_01122 6e-188 S Virulence-associated protein E
GFNHDNMA_01123 8.9e-102 S Bifunctional DNA primase/polymerase, N-terminal
GFNHDNMA_01124 2.3e-13
GFNHDNMA_01125 9.3e-40
GFNHDNMA_01126 4.7e-108 L AAA domain
GFNHDNMA_01128 8.1e-08 K sequence-specific DNA binding
GFNHDNMA_01129 2.9e-211 res L Helicase C-terminal domain protein
GFNHDNMA_01132 8.6e-44 S Siphovirus Gp157
GFNHDNMA_01134 2.6e-15
GFNHDNMA_01135 2.4e-30
GFNHDNMA_01137 6e-17 ps115 K Helix-turn-helix XRE-family like proteins
GFNHDNMA_01138 1.6e-67 E Zn peptidase
GFNHDNMA_01139 1.2e-30 S Bacterial PH domain
GFNHDNMA_01140 2.4e-220 sip L Belongs to the 'phage' integrase family
GFNHDNMA_01142 4.3e-155 lysR5 K LysR substrate binding domain
GFNHDNMA_01143 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
GFNHDNMA_01144 6.6e-251 G Major Facilitator
GFNHDNMA_01145 2.5e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GFNHDNMA_01146 1.4e-186 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GFNHDNMA_01147 9.9e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFNHDNMA_01148 1.5e-275 yjeM E Amino Acid
GFNHDNMA_01149 4.8e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GFNHDNMA_01150 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
GFNHDNMA_01151 7.1e-124 srtA 3.4.22.70 M sortase family
GFNHDNMA_01152 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GFNHDNMA_01153 5.7e-174 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GFNHDNMA_01154 0.0 dnaK O Heat shock 70 kDa protein
GFNHDNMA_01155 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GFNHDNMA_01156 2.5e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GFNHDNMA_01157 4.8e-95 S GyrI-like small molecule binding domain
GFNHDNMA_01158 1.8e-281 lsa S ABC transporter
GFNHDNMA_01159 1.3e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GFNHDNMA_01160 9.8e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GFNHDNMA_01161 3.5e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GFNHDNMA_01162 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GFNHDNMA_01163 1.3e-45 rplGA J ribosomal protein
GFNHDNMA_01164 1.5e-46 ylxR K Protein of unknown function (DUF448)
GFNHDNMA_01165 9.4e-220 nusA K Participates in both transcription termination and antitermination
GFNHDNMA_01166 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
GFNHDNMA_01167 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GFNHDNMA_01168 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GFNHDNMA_01169 9.3e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GFNHDNMA_01170 1.5e-138 cdsA 2.7.7.41 S Belongs to the CDS family
GFNHDNMA_01171 8.5e-136 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GFNHDNMA_01172 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GFNHDNMA_01173 1.8e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GFNHDNMA_01174 3.5e-183 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GFNHDNMA_01175 5.8e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
GFNHDNMA_01176 8.8e-195 yabB 2.1.1.223 L Methyltransferase small domain
GFNHDNMA_01177 2.6e-117 plsC 2.3.1.51 I Acyltransferase
GFNHDNMA_01178 3e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
GFNHDNMA_01179 1e-283 mdlB V ABC transporter
GFNHDNMA_01180 0.0 mdlA V ABC transporter
GFNHDNMA_01181 3.3e-30 yneF S Uncharacterised protein family (UPF0154)
GFNHDNMA_01182 9.4e-34 ynzC S UPF0291 protein
GFNHDNMA_01183 1e-113 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GFNHDNMA_01184 3.5e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
GFNHDNMA_01185 3.1e-69 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
GFNHDNMA_01186 2.1e-117 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GFNHDNMA_01187 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GFNHDNMA_01188 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GFNHDNMA_01189 1.2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GFNHDNMA_01190 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GFNHDNMA_01191 3.8e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GFNHDNMA_01192 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GFNHDNMA_01193 7.5e-285 pipD E Dipeptidase
GFNHDNMA_01194 2.4e-165 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GFNHDNMA_01195 0.0 smc D Required for chromosome condensation and partitioning
GFNHDNMA_01196 2e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GFNHDNMA_01197 0.0 oppA E ABC transporter substrate-binding protein
GFNHDNMA_01198 0.0 oppA E ABC transporter substrate-binding protein
GFNHDNMA_01199 1.1e-161 oppC P Binding-protein-dependent transport system inner membrane component
GFNHDNMA_01200 5.6e-175 oppB P ABC transporter permease
GFNHDNMA_01201 9.9e-180 oppF P Belongs to the ABC transporter superfamily
GFNHDNMA_01202 9e-192 oppD P Belongs to the ABC transporter superfamily
GFNHDNMA_01203 4.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFNHDNMA_01204 7.1e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GFNHDNMA_01205 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GFNHDNMA_01206 3.1e-306 yloV S DAK2 domain fusion protein YloV
GFNHDNMA_01207 1.4e-57 asp S Asp23 family, cell envelope-related function
GFNHDNMA_01208 1.2e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GFNHDNMA_01209 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
GFNHDNMA_01210 4.1e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GFNHDNMA_01211 4.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GFNHDNMA_01212 0.0 KLT serine threonine protein kinase
GFNHDNMA_01213 7.8e-140 stp 3.1.3.16 T phosphatase
GFNHDNMA_01214 1.9e-242 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GFNHDNMA_01215 2.3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GFNHDNMA_01216 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GFNHDNMA_01217 2.3e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GFNHDNMA_01218 7.3e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
GFNHDNMA_01219 1e-47
GFNHDNMA_01220 0.0 3.1.31.1 M domain protein
GFNHDNMA_01221 0.0 infB UW LPXTG-motif cell wall anchor domain protein
GFNHDNMA_01222 0.0 S domain, Protein
GFNHDNMA_01223 1.5e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GFNHDNMA_01224 1.1e-98 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
GFNHDNMA_01225 1.2e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GFNHDNMA_01226 1.2e-252 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
GFNHDNMA_01227 2.4e-171 K AI-2E family transporter
GFNHDNMA_01228 4.1e-26
GFNHDNMA_01229 3.9e-208 EGP Major facilitator Superfamily
GFNHDNMA_01230 2.2e-154 ropB K Transcriptional regulator
GFNHDNMA_01233 4.8e-19 HJ RimK-like ATP-grasp domain
GFNHDNMA_01234 1e-85 V ABC-type multidrug transport system, ATPase and permease components
GFNHDNMA_01236 2.5e-09 S Protein of unknown function (DUF2922)
GFNHDNMA_01237 5.2e-40 L Single-strand binding protein family
GFNHDNMA_01238 1.1e-16
GFNHDNMA_01240 1.2e-29
GFNHDNMA_01241 1.7e-07
GFNHDNMA_01242 1.9e-137 S Alpha beta hydrolase
GFNHDNMA_01243 0.0 L Helicase C-terminal domain protein
GFNHDNMA_01244 2.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
GFNHDNMA_01245 4.2e-40 S Transglycosylase associated protein
GFNHDNMA_01247 1.1e-199 XK27_02480 EGP Major facilitator Superfamily
GFNHDNMA_01248 3.3e-142 ropB K Helix-turn-helix XRE-family like proteins
GFNHDNMA_01249 0.0 pepO 3.4.24.71 O Peptidase family M13
GFNHDNMA_01250 2.7e-236 clcA P chloride
GFNHDNMA_01251 0.0 tetP J elongation factor G
GFNHDNMA_01252 3.3e-144 ropB K Helix-turn-helix domain
GFNHDNMA_01253 3.3e-289 V ABC-type multidrug transport system, ATPase and permease components
GFNHDNMA_01254 3.5e-17
GFNHDNMA_01255 3.1e-153 yitS S EDD domain protein, DegV family
GFNHDNMA_01256 1.3e-136 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GFNHDNMA_01257 9e-127 S Protein of unknown function (DUF975)
GFNHDNMA_01258 6.4e-60 ywnB S NAD(P)H-binding
GFNHDNMA_01259 0.0 tetP J Elongation factor G, domain IV
GFNHDNMA_01260 1.1e-18 S Protein of unknown function (DUF975)
GFNHDNMA_01261 9.7e-115 ywnB S NAD(P)H-binding
GFNHDNMA_01262 1.7e-159 arbZ I Acyltransferase
GFNHDNMA_01263 7.6e-219 S Sterol carrier protein domain
GFNHDNMA_01265 5e-246 steT E amino acid
GFNHDNMA_01267 0.0
GFNHDNMA_01268 1.8e-217 I Protein of unknown function (DUF2974)
GFNHDNMA_01269 7.6e-171 scrK 2.7.1.2, 2.7.1.4 GK ROK family
GFNHDNMA_01270 1.6e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GFNHDNMA_01271 8.2e-76 rplI J Binds to the 23S rRNA
GFNHDNMA_01272 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GFNHDNMA_01273 3.5e-158 corA P CorA-like Mg2+ transporter protein
GFNHDNMA_01274 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GFNHDNMA_01275 1.3e-80 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GFNHDNMA_01276 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
GFNHDNMA_01277 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GFNHDNMA_01278 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GFNHDNMA_01279 7.6e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GFNHDNMA_01280 1.6e-20 yaaA S S4 domain
GFNHDNMA_01281 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GFNHDNMA_01282 4.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GFNHDNMA_01283 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GFNHDNMA_01284 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GFNHDNMA_01285 1.6e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GFNHDNMA_01286 1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GFNHDNMA_01287 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GFNHDNMA_01288 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
GFNHDNMA_01289 2.3e-270 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GFNHDNMA_01290 3.5e-288 clcA P chloride
GFNHDNMA_01291 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GFNHDNMA_01292 5.1e-12 S RelB antitoxin
GFNHDNMA_01293 5.1e-69 S Iron-sulphur cluster biosynthesis
GFNHDNMA_01294 5.6e-231 EGP Sugar (and other) transporter
GFNHDNMA_01295 2.1e-70 K Acetyltransferase (GNAT) domain
GFNHDNMA_01296 6.5e-248 ynbB 4.4.1.1 P aluminum resistance
GFNHDNMA_01297 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
GFNHDNMA_01298 1.3e-279 E Amino acid permease
GFNHDNMA_01299 0.0 copA 3.6.3.54 P P-type ATPase
GFNHDNMA_01300 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GFNHDNMA_01301 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
GFNHDNMA_01302 5e-75 atkY K Penicillinase repressor
GFNHDNMA_01303 3.2e-90
GFNHDNMA_01304 1.3e-75
GFNHDNMA_01305 3.9e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GFNHDNMA_01306 3.9e-76 K Bacteriophage CI repressor helix-turn-helix domain
GFNHDNMA_01307 1.1e-226 pbuG S permease
GFNHDNMA_01308 1.5e-231 pbuG S permease
GFNHDNMA_01309 3.8e-112 K helix_turn_helix, mercury resistance
GFNHDNMA_01310 6.7e-232 pbuG S permease
GFNHDNMA_01311 2.8e-235 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
GFNHDNMA_01312 6.3e-125 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GFNHDNMA_01313 1e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
GFNHDNMA_01314 7.9e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GFNHDNMA_01315 3.1e-161 yeaE S Aldo/keto reductase family
GFNHDNMA_01316 1.1e-130 S membrane transporter protein
GFNHDNMA_01317 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GFNHDNMA_01318 8.3e-149 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GFNHDNMA_01319 6.4e-164 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
GFNHDNMA_01320 1.3e-146 K Helix-turn-helix domain, rpiR family
GFNHDNMA_01321 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
GFNHDNMA_01322 2.1e-96 M Protein of unknown function (DUF3737)
GFNHDNMA_01323 5.1e-223 patB 4.4.1.8 E Aminotransferase, class I
GFNHDNMA_01324 1.2e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
GFNHDNMA_01325 6e-67 S SdpI/YhfL protein family
GFNHDNMA_01326 7.6e-129 K Transcriptional regulatory protein, C terminal
GFNHDNMA_01327 2.9e-268 T PhoQ Sensor
GFNHDNMA_01328 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GFNHDNMA_01329 1.3e-105 vanZ V VanZ like family
GFNHDNMA_01330 1.9e-261 pgi 5.3.1.9 G Belongs to the GPI family
GFNHDNMA_01331 3e-230 EGP Major facilitator Superfamily
GFNHDNMA_01332 3.2e-69
GFNHDNMA_01335 3.3e-194 ampC V Beta-lactamase
GFNHDNMA_01336 1.1e-261 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
GFNHDNMA_01337 2.7e-111 tdk 2.7.1.21 F thymidine kinase
GFNHDNMA_01338 2.9e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GFNHDNMA_01339 2.1e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GFNHDNMA_01340 2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GFNHDNMA_01341 1.5e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GFNHDNMA_01342 5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
GFNHDNMA_01343 4.7e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GFNHDNMA_01344 3.1e-52 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GFNHDNMA_01345 9.8e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GFNHDNMA_01346 6.7e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GFNHDNMA_01347 5.4e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GFNHDNMA_01348 9.6e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GFNHDNMA_01349 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GFNHDNMA_01350 2.4e-31 ywzB S Protein of unknown function (DUF1146)
GFNHDNMA_01351 1.7e-179 mbl D Cell shape determining protein MreB Mrl
GFNHDNMA_01352 6.8e-13 S DNA-directed RNA polymerase subunit beta
GFNHDNMA_01353 2.6e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
GFNHDNMA_01354 6.6e-34 S Protein of unknown function (DUF2969)
GFNHDNMA_01355 2.3e-223 rodA D Belongs to the SEDS family
GFNHDNMA_01356 5.2e-81 usp6 T universal stress protein
GFNHDNMA_01358 1.1e-239 rarA L recombination factor protein RarA
GFNHDNMA_01359 2.4e-83 yueI S Protein of unknown function (DUF1694)
GFNHDNMA_01360 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GFNHDNMA_01362 1.1e-290 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GFNHDNMA_01363 4.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
GFNHDNMA_01364 1.1e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFNHDNMA_01365 2.5e-124 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GFNHDNMA_01366 1.5e-179 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
GFNHDNMA_01367 0.0 3.6.3.8 P P-type ATPase
GFNHDNMA_01368 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GFNHDNMA_01369 8.2e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GFNHDNMA_01370 7.8e-123 S Haloacid dehalogenase-like hydrolase
GFNHDNMA_01371 2.1e-111 radC L DNA repair protein
GFNHDNMA_01372 2.7e-164 mreB D cell shape determining protein MreB
GFNHDNMA_01373 1.8e-140 mreC M Involved in formation and maintenance of cell shape
GFNHDNMA_01374 2.7e-94 mreD
GFNHDNMA_01375 3.6e-13 S Protein of unknown function (DUF4044)
GFNHDNMA_01376 2.7e-52 S Protein of unknown function (DUF3397)
GFNHDNMA_01377 4.1e-77 mraZ K Belongs to the MraZ family
GFNHDNMA_01378 1.1e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GFNHDNMA_01379 4.8e-55 ftsL D Cell division protein FtsL
GFNHDNMA_01380 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
GFNHDNMA_01381 1.2e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GFNHDNMA_01382 1.1e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GFNHDNMA_01383 1.8e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GFNHDNMA_01384 3.4e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GFNHDNMA_01385 6e-239 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GFNHDNMA_01386 1.1e-243 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GFNHDNMA_01387 1.3e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GFNHDNMA_01388 1.2e-27 yggT S YGGT family
GFNHDNMA_01389 3.8e-145 ylmH S S4 domain protein
GFNHDNMA_01390 4.2e-120 gpsB D DivIVA domain protein
GFNHDNMA_01391 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GFNHDNMA_01392 2.3e-33 cspA K 'Cold-shock' DNA-binding domain
GFNHDNMA_01393 1.7e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
GFNHDNMA_01394 4.9e-34
GFNHDNMA_01395 1.1e-127 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GFNHDNMA_01396 3e-215 iscS 2.8.1.7 E Aminotransferase class V
GFNHDNMA_01397 9.6e-58 XK27_04120 S Putative amino acid metabolism
GFNHDNMA_01398 2.8e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GFNHDNMA_01399 8.9e-124 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
GFNHDNMA_01400 1.5e-115 S Repeat protein
GFNHDNMA_01401 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GFNHDNMA_01402 7.8e-174 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
GFNHDNMA_01403 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GFNHDNMA_01404 2.3e-34 ykzG S Belongs to the UPF0356 family
GFNHDNMA_01405 5.2e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GFNHDNMA_01406 0.0 typA T GTP-binding protein TypA
GFNHDNMA_01407 1.7e-210 ftsW D Belongs to the SEDS family
GFNHDNMA_01408 7.4e-50 ylbG S UPF0298 protein
GFNHDNMA_01409 2.5e-95 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
GFNHDNMA_01410 2.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GFNHDNMA_01411 1.1e-184 ylbL T Belongs to the peptidase S16 family
GFNHDNMA_01412 4.2e-84 comEA L Competence protein ComEA
GFNHDNMA_01413 0.0 comEC S Competence protein ComEC
GFNHDNMA_01414 1.5e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
GFNHDNMA_01415 4.4e-34 rpsT J Binds directly to 16S ribosomal RNA
GFNHDNMA_01416 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GFNHDNMA_01417 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GFNHDNMA_01418 1.4e-158
GFNHDNMA_01419 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GFNHDNMA_01420 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GFNHDNMA_01421 2.6e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GFNHDNMA_01422 1.7e-102 engB D Necessary for normal cell division and for the maintenance of normal septation
GFNHDNMA_01423 2.2e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFNHDNMA_01424 5.1e-82
GFNHDNMA_01426 8e-117 frnE Q DSBA-like thioredoxin domain
GFNHDNMA_01427 4.2e-74 S Domain of unknown function (DUF4767)
GFNHDNMA_01428 1.3e-216
GFNHDNMA_01429 2.1e-120 frnE Q DSBA-like thioredoxin domain
GFNHDNMA_01430 2.1e-162
GFNHDNMA_01431 1.6e-77 K DNA-templated transcription, initiation
GFNHDNMA_01432 1.7e-150 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GFNHDNMA_01433 5.6e-142 epsB M biosynthesis protein
GFNHDNMA_01434 6.6e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
GFNHDNMA_01435 1.7e-142 ywqE 3.1.3.48 GM PHP domain protein
GFNHDNMA_01436 5.1e-119 rfbP M Bacterial sugar transferase
GFNHDNMA_01437 8.3e-56
GFNHDNMA_01438 8.1e-205 rgpAc GT4 M Domain of unknown function (DUF1972)
GFNHDNMA_01439 4e-111 wcoF M Glycosyl transferases group 1
GFNHDNMA_01440 3.3e-41 S Glycosyl transferase family 2
GFNHDNMA_01441 2.9e-76 cps1B GT2,GT4 M Glycosyl transferases group 1
GFNHDNMA_01442 3.1e-99 wbbI M transferase activity, transferring glycosyl groups
GFNHDNMA_01443 1.5e-208 glf 5.4.99.9 M UDP-galactopyranose mutase
GFNHDNMA_01444 2.9e-252 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
GFNHDNMA_01445 2.7e-32
GFNHDNMA_01446 1.5e-112 rsmC 2.1.1.172 J Methyltransferase
GFNHDNMA_01447 3.9e-21
GFNHDNMA_01448 9e-145
GFNHDNMA_01449 1.5e-39 S Protein conserved in bacteria
GFNHDNMA_01450 1e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GFNHDNMA_01451 1.1e-293 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GFNHDNMA_01452 1.7e-51 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GFNHDNMA_01453 8.1e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GFNHDNMA_01454 9e-26 S Protein of unknown function (DUF2508)
GFNHDNMA_01455 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GFNHDNMA_01456 5e-51 yaaQ S Cyclic-di-AMP receptor
GFNHDNMA_01457 3.1e-153 holB 2.7.7.7 L DNA polymerase III
GFNHDNMA_01458 4.4e-58 yabA L Involved in initiation control of chromosome replication
GFNHDNMA_01459 3.7e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GFNHDNMA_01460 6.4e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
GFNHDNMA_01461 1.3e-85 folT S ECF transporter, substrate-specific component
GFNHDNMA_01462 1.2e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
GFNHDNMA_01463 1.1e-95 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
GFNHDNMA_01464 3.6e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GFNHDNMA_01465 8.7e-166 D nuclear chromosome segregation
GFNHDNMA_01466 3.6e-152
GFNHDNMA_01467 7.2e-115
GFNHDNMA_01468 6.9e-248 clcA P chloride
GFNHDNMA_01469 2.4e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GFNHDNMA_01470 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GFNHDNMA_01471 6.4e-243 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GFNHDNMA_01472 6.1e-137 L oxidized base lesion DNA N-glycosylase activity
GFNHDNMA_01473 3.4e-74 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
GFNHDNMA_01474 5.7e-31
GFNHDNMA_01475 3.6e-39
GFNHDNMA_01476 5.7e-188 2.7.13.3 T GHKL domain
GFNHDNMA_01477 1.6e-137 K LytTr DNA-binding domain
GFNHDNMA_01478 7.8e-140 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GFNHDNMA_01479 2e-149 K Helix-turn-helix XRE-family like proteins
GFNHDNMA_01480 7.1e-83
GFNHDNMA_01481 4.6e-241 G Bacterial extracellular solute-binding protein
GFNHDNMA_01482 0.0 uup S ABC transporter, ATP-binding protein
GFNHDNMA_01483 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GFNHDNMA_01484 2e-103 yvdD 3.2.2.10 S Belongs to the LOG family
GFNHDNMA_01486 1.1e-127 K Psort location Cytoplasmic, score 8.87
GFNHDNMA_01487 2.9e-22 S Domain of unknown function (DUF3284)
GFNHDNMA_01488 5.4e-24 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
GFNHDNMA_01489 8.8e-21 pts15B 2.7.1.196, 2.7.1.205 G system, Lactose Cellobiose specific IIB subunit
GFNHDNMA_01490 1.1e-131 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GFNHDNMA_01491 1.5e-240 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GFNHDNMA_01492 6.1e-79 XK27_02470 K LytTr DNA-binding domain
GFNHDNMA_01493 1.2e-119 liaI S membrane
GFNHDNMA_01495 2e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GFNHDNMA_01496 1.8e-295 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GFNHDNMA_01497 2.4e-110
GFNHDNMA_01498 0.0 nisT V ABC transporter
GFNHDNMA_01499 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GFNHDNMA_01500 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GFNHDNMA_01501 9.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GFNHDNMA_01502 4.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GFNHDNMA_01503 1.2e-39 yajC U Preprotein translocase
GFNHDNMA_01504 1.2e-282 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GFNHDNMA_01505 4.9e-207 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFNHDNMA_01506 3.3e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
GFNHDNMA_01507 4e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GFNHDNMA_01508 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GFNHDNMA_01509 2.6e-42 yrzL S Belongs to the UPF0297 family
GFNHDNMA_01510 2.6e-71 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GFNHDNMA_01511 1.2e-38 yrzB S Belongs to the UPF0473 family
GFNHDNMA_01512 1.9e-92 cvpA S Colicin V production protein
GFNHDNMA_01513 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GFNHDNMA_01514 1.1e-52 trxA O Belongs to the thioredoxin family
GFNHDNMA_01515 3.2e-68 yslB S Protein of unknown function (DUF2507)
GFNHDNMA_01517 7.5e-42 L Replication initiation factor
GFNHDNMA_01518 1.7e-08
GFNHDNMA_01524 7.5e-13
GFNHDNMA_01525 1.4e-19 K sequence-specific DNA binding
GFNHDNMA_01526 4e-61 sip L Belongs to the 'phage' integrase family
GFNHDNMA_01527 5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GFNHDNMA_01528 1.5e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GFNHDNMA_01529 2.5e-96 UW LPXTG-motif cell wall anchor domain protein
GFNHDNMA_01530 0.0 UW LPXTG-motif cell wall anchor domain protein
GFNHDNMA_01531 3e-215 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GFNHDNMA_01532 6e-139 ykuT M mechanosensitive ion channel
GFNHDNMA_01533 1.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GFNHDNMA_01534 8.1e-49
GFNHDNMA_01535 5.5e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
GFNHDNMA_01536 9.8e-175 ccpA K catabolite control protein A
GFNHDNMA_01537 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
GFNHDNMA_01538 4e-275 pepV 3.5.1.18 E dipeptidase PepV
GFNHDNMA_01539 5.2e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GFNHDNMA_01540 3.7e-54
GFNHDNMA_01541 3.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
GFNHDNMA_01542 2.4e-95 yutD S Protein of unknown function (DUF1027)
GFNHDNMA_01543 1.2e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GFNHDNMA_01544 1.1e-102 S Protein of unknown function (DUF1461)
GFNHDNMA_01545 2.7e-117 dedA S SNARE-like domain protein
GFNHDNMA_01546 3.1e-178 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
GFNHDNMA_01547 4.2e-62 yugI 5.3.1.9 J general stress protein
GFNHDNMA_01548 3.7e-271 E amino acid
GFNHDNMA_01549 8.9e-170 K LysR substrate binding domain
GFNHDNMA_01550 0.0 1.3.5.4 C FAD binding domain
GFNHDNMA_01551 7.5e-226 brnQ U Component of the transport system for branched-chain amino acids
GFNHDNMA_01552 2.8e-134 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GFNHDNMA_01553 3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
GFNHDNMA_01554 5.9e-185 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
GFNHDNMA_01555 2.6e-247 yhjX_2 P Major Facilitator Superfamily
GFNHDNMA_01556 8.5e-246 yhjX_2 P Major Facilitator Superfamily
GFNHDNMA_01557 0.0 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
GFNHDNMA_01558 8.2e-162 arbZ I Phosphate acyltransferases
GFNHDNMA_01559 9.4e-183 arbY M Glycosyl transferase family 8
GFNHDNMA_01560 1.6e-182 arbY M Glycosyl transferase family 8
GFNHDNMA_01561 1.5e-152 arbx M Glycosyl transferase family 8
GFNHDNMA_01562 2e-143 arbV 2.3.1.51 I Acyl-transferase
GFNHDNMA_01565 1.3e-128 K response regulator
GFNHDNMA_01566 0.0 vicK 2.7.13.3 T Histidine kinase
GFNHDNMA_01567 8.9e-248 yycH S YycH protein
GFNHDNMA_01568 6.7e-145 yycI S YycH protein
GFNHDNMA_01569 3.7e-148 vicX 3.1.26.11 S domain protein
GFNHDNMA_01570 6.4e-176 htrA 3.4.21.107 O serine protease
GFNHDNMA_01571 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GFNHDNMA_01572 1.9e-110 P Cobalt transport protein
GFNHDNMA_01573 1.4e-245 cbiO1 S ABC transporter, ATP-binding protein
GFNHDNMA_01574 7.9e-97 S ABC-type cobalt transport system, permease component
GFNHDNMA_01575 2.8e-168 K helix_turn_helix, arabinose operon control protein
GFNHDNMA_01576 2.2e-162 htpX O Belongs to the peptidase M48B family
GFNHDNMA_01577 3.2e-90 lemA S LemA family
GFNHDNMA_01578 6.6e-180 ybiR P Citrate transporter
GFNHDNMA_01579 2.6e-65 S Iron-sulphur cluster biosynthesis
GFNHDNMA_01580 1.7e-16
GFNHDNMA_01581 8.8e-73
GFNHDNMA_01582 5.8e-54
GFNHDNMA_01584 3.3e-239 ydaM M Glycosyl transferase
GFNHDNMA_01585 4.5e-200 G Glycosyl hydrolases family 8
GFNHDNMA_01586 4.5e-120 yfbR S HD containing hydrolase-like enzyme
GFNHDNMA_01587 5.4e-175 L HNH nucleases
GFNHDNMA_01588 2e-45
GFNHDNMA_01589 1.8e-136 glnQ E ABC transporter, ATP-binding protein
GFNHDNMA_01590 7.4e-297 glnP P ABC transporter permease
GFNHDNMA_01591 6.5e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
GFNHDNMA_01592 4.4e-64 yeaO S Protein of unknown function, DUF488
GFNHDNMA_01593 3.6e-124 terC P Integral membrane protein TerC family
GFNHDNMA_01594 7.8e-86 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
GFNHDNMA_01595 5.5e-135 cobB K SIR2 family
GFNHDNMA_01596 2.6e-80
GFNHDNMA_01597 2.8e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFNHDNMA_01598 2.1e-123 yugP S Putative neutral zinc metallopeptidase
GFNHDNMA_01599 7.7e-174 S Alpha/beta hydrolase of unknown function (DUF915)
GFNHDNMA_01600 2.2e-69 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GFNHDNMA_01601 4.6e-54 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GFNHDNMA_01603 2.4e-157 ypuA S Protein of unknown function (DUF1002)
GFNHDNMA_01604 1.3e-151 epsV 2.7.8.12 S glycosyl transferase family 2
GFNHDNMA_01605 4e-124 S Alpha/beta hydrolase family
GFNHDNMA_01606 1.2e-61
GFNHDNMA_01607 4.5e-180 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFNHDNMA_01608 1.2e-239 cycA E Amino acid permease
GFNHDNMA_01609 2.3e-111 luxT K Bacterial regulatory proteins, tetR family
GFNHDNMA_01610 4e-121
GFNHDNMA_01611 3.7e-266 S Cysteine-rich secretory protein family
GFNHDNMA_01612 1.4e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GFNHDNMA_01613 6.8e-77
GFNHDNMA_01614 1.2e-272 yjcE P Sodium proton antiporter
GFNHDNMA_01615 8.9e-169 yibE S overlaps another CDS with the same product name
GFNHDNMA_01616 4.9e-118 yibF S overlaps another CDS with the same product name
GFNHDNMA_01617 6.7e-153 I alpha/beta hydrolase fold
GFNHDNMA_01618 0.0 G Belongs to the glycosyl hydrolase 31 family
GFNHDNMA_01619 3.2e-127 XK27_08435 K UTRA
GFNHDNMA_01620 1.4e-212 agaS G SIS domain
GFNHDNMA_01621 1.7e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GFNHDNMA_01622 1.3e-82 2.7.1.191 G PTS system sorbose subfamily IIB component
GFNHDNMA_01623 7.5e-129 XK27_08455 G PTS system sorbose-specific iic component
GFNHDNMA_01624 7.1e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
GFNHDNMA_01625 8.7e-66 2.7.1.191 G PTS system fructose IIA component
GFNHDNMA_01626 3.1e-215 S zinc-ribbon domain
GFNHDNMA_01627 4.8e-87 ntd 2.4.2.6 F Nucleoside
GFNHDNMA_01628 1e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GFNHDNMA_01629 5.4e-130 XK27_08440 K UTRA domain
GFNHDNMA_01630 3.4e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
GFNHDNMA_01631 1e-87 uspA T universal stress protein
GFNHDNMA_01633 6.2e-244 cycA E Amino acid permease
GFNHDNMA_01634 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GFNHDNMA_01635 2.5e-71
GFNHDNMA_01636 2.2e-104 4.1.1.44 S Carboxymuconolactone decarboxylase family
GFNHDNMA_01637 0.0 S TerB-C domain
GFNHDNMA_01638 3.2e-253 P P-loop Domain of unknown function (DUF2791)
GFNHDNMA_01639 0.0 lhr L DEAD DEAH box helicase
GFNHDNMA_01640 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GFNHDNMA_01641 3.1e-144 S Uncharacterized protein conserved in bacteria (DUF2263)
GFNHDNMA_01642 7.5e-247 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
GFNHDNMA_01643 9.7e-163 yvgN C Aldo keto reductase
GFNHDNMA_01645 1.9e-89 K acetyltransferase
GFNHDNMA_01646 1.5e-60 psiE S Phosphate-starvation-inducible E
GFNHDNMA_01647 6.7e-133 S Putative ABC-transporter type IV
GFNHDNMA_01648 4.6e-114 M LysM domain protein
GFNHDNMA_01649 1.1e-98 M LysM domain protein
GFNHDNMA_01651 2.5e-31 yjgN S Bacterial protein of unknown function (DUF898)
GFNHDNMA_01652 1.9e-36 K SIS domain
GFNHDNMA_01653 2.9e-165 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
GFNHDNMA_01656 5.5e-52 P Rhodanese Homology Domain
GFNHDNMA_01657 2.7e-189
GFNHDNMA_01658 3.6e-123 gntR1 K UTRA
GFNHDNMA_01659 7.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
GFNHDNMA_01660 1.8e-133 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GFNHDNMA_01661 2.8e-202 csaB M Glycosyl transferases group 1
GFNHDNMA_01662 0.0 S Glycosyltransferase like family 2
GFNHDNMA_01663 6.5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GFNHDNMA_01664 2.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GFNHDNMA_01665 0.0 spoVK O ATPase family associated with various cellular activities (AAA)
GFNHDNMA_01666 0.0 pacL 3.6.3.8 P P-type ATPase
GFNHDNMA_01667 1.1e-284 V ABC transporter transmembrane region
GFNHDNMA_01668 1.3e-132
GFNHDNMA_01669 1e-223 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GFNHDNMA_01670 6.7e-257 epsU S Polysaccharide biosynthesis protein
GFNHDNMA_01671 4.2e-132 M Glycosyltransferase sugar-binding region containing DXD motif
GFNHDNMA_01672 2.1e-79 ydcK S Belongs to the SprT family
GFNHDNMA_01674 5.3e-102 S ECF transporter, substrate-specific component
GFNHDNMA_01675 4.4e-112 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
GFNHDNMA_01676 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GFNHDNMA_01677 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GFNHDNMA_01678 6.5e-207 camS S sex pheromone
GFNHDNMA_01679 3.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GFNHDNMA_01680 1.8e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GFNHDNMA_01681 6e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GFNHDNMA_01682 1.2e-166 yegS 2.7.1.107 G Lipid kinase
GFNHDNMA_01684 2.9e-148 S hydrolase
GFNHDNMA_01686 2.9e-27 UW Tetratricopeptide repeat
GFNHDNMA_01687 1.9e-84 UW Tetratricopeptide repeat
GFNHDNMA_01688 4.3e-34 UW Tetratricopeptide repeat
GFNHDNMA_01689 1e-61 UW Tetratricopeptide repeat
GFNHDNMA_01690 6e-171 UW Tetratricopeptide repeat
GFNHDNMA_01691 0.0 GT2,GT4 M family 8
GFNHDNMA_01692 0.0 GT2,GT4 M family 8
GFNHDNMA_01693 2.7e-118 ybhL S Belongs to the BI1 family
GFNHDNMA_01694 6.3e-143 cbiQ P cobalt transport
GFNHDNMA_01695 0.0 ykoD P ABC transporter, ATP-binding protein
GFNHDNMA_01696 3.3e-95 S UPF0397 protein
GFNHDNMA_01697 1.9e-158 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
GFNHDNMA_01698 4.4e-242 nhaC C Na H antiporter NhaC
GFNHDNMA_01699 3.9e-125 mutF V ABC transporter, ATP-binding protein
GFNHDNMA_01700 5.8e-118 spaE S ABC-2 family transporter protein
GFNHDNMA_01701 2.8e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GFNHDNMA_01702 1.3e-196 tcsA S ABC transporter substrate-binding protein PnrA-like
GFNHDNMA_01703 3.7e-168 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
GFNHDNMA_01704 1.2e-236 G Bacterial extracellular solute-binding protein
GFNHDNMA_01705 2.8e-176 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
GFNHDNMA_01706 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GFNHDNMA_01707 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GFNHDNMA_01708 1.7e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
GFNHDNMA_01709 1.9e-269 cydA 1.10.3.14 C ubiquinol oxidase
GFNHDNMA_01710 0.0 macB_3 V ABC transporter, ATP-binding protein
GFNHDNMA_01711 1.8e-201 S DUF218 domain
GFNHDNMA_01712 3.5e-104 S CAAX protease self-immunity
GFNHDNMA_01713 1.4e-87 S Protein of unknown function (DUF1440)
GFNHDNMA_01714 8.4e-16
GFNHDNMA_01715 5.7e-07
GFNHDNMA_01716 4.9e-87 S Protein of unknown function (DUF805)
GFNHDNMA_01717 2.8e-112 S Protein of unknown function (DUF969)
GFNHDNMA_01718 1.9e-156 S Protein of unknown function (DUF979)
GFNHDNMA_01719 2.9e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GFNHDNMA_01720 2.3e-34
GFNHDNMA_01721 7e-153 mutR K Helix-turn-helix XRE-family like proteins
GFNHDNMA_01722 3.8e-274 V ABC transporter transmembrane region
GFNHDNMA_01723 1.9e-86 S Putative adhesin
GFNHDNMA_01724 2.4e-201 napA P Sodium/hydrogen exchanger family
GFNHDNMA_01725 0.0 cadA P P-type ATPase
GFNHDNMA_01726 5.7e-83 ykuL S (CBS) domain
GFNHDNMA_01727 1.7e-199 ywhK S Membrane
GFNHDNMA_01728 3.9e-39
GFNHDNMA_01730 7.4e-291 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GFNHDNMA_01731 6.1e-235 dltB M MBOAT, membrane-bound O-acyltransferase family
GFNHDNMA_01732 6.7e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GFNHDNMA_01733 1.2e-249 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GFNHDNMA_01734 2.9e-145 pbpX2 V Beta-lactamase
GFNHDNMA_01735 3.6e-216 lmrP E Major Facilitator Superfamily
GFNHDNMA_01736 7.8e-38
GFNHDNMA_01737 2.7e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GFNHDNMA_01738 6.6e-162 S Alpha/beta hydrolase of unknown function (DUF915)
GFNHDNMA_01739 0.0 clpE2 O AAA domain (Cdc48 subfamily)
GFNHDNMA_01740 5e-249 yfnA E Amino Acid
GFNHDNMA_01741 2.6e-35 L transposase activity
GFNHDNMA_01742 1.1e-109 L COG2963 Transposase and inactivated derivatives
GFNHDNMA_01743 2.6e-62 gadC E Contains amino acid permease domain
GFNHDNMA_01744 1.1e-264 pepC 3.4.22.40 E Peptidase C1-like family
GFNHDNMA_01745 2.3e-187 brpA K Cell envelope-like function transcriptional attenuator common domain protein
GFNHDNMA_01746 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
GFNHDNMA_01747 5.4e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GFNHDNMA_01748 1.5e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFNHDNMA_01749 7.9e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GFNHDNMA_01750 8.5e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GFNHDNMA_01751 2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFNHDNMA_01752 1e-88 yvrI K sigma factor activity
GFNHDNMA_01753 1.7e-34
GFNHDNMA_01754 2.6e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
GFNHDNMA_01755 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GFNHDNMA_01756 1.6e-227 G Major Facilitator Superfamily
GFNHDNMA_01757 2.8e-188 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GFNHDNMA_01758 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GFNHDNMA_01759 3.4e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GFNHDNMA_01760 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
GFNHDNMA_01761 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GFNHDNMA_01762 1.8e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GFNHDNMA_01763 1.4e-108 glnP P ABC transporter permease
GFNHDNMA_01764 2e-115 glnQ 3.6.3.21 E ABC transporter
GFNHDNMA_01765 4.9e-145 aatB ET ABC transporter substrate-binding protein
GFNHDNMA_01766 4.2e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GFNHDNMA_01767 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GFNHDNMA_01768 2.2e-101 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
GFNHDNMA_01770 4e-184 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
GFNHDNMA_01771 1.3e-124 manY G PTS system
GFNHDNMA_01772 1.1e-172 manN G system, mannose fructose sorbose family IID component
GFNHDNMA_01773 1.8e-65 manO S Domain of unknown function (DUF956)
GFNHDNMA_01774 2.5e-253 yifK E Amino acid permease
GFNHDNMA_01775 3.5e-231 yifK E Amino acid permease
GFNHDNMA_01776 9.5e-135 puuD S peptidase C26
GFNHDNMA_01777 1.2e-234 steT_1 E amino acid
GFNHDNMA_01778 9e-192 asnA 6.3.1.1 F aspartate--ammonia ligase
GFNHDNMA_01779 3.9e-162 EG EamA-like transporter family
GFNHDNMA_01780 4.6e-255 yfnA E Amino Acid
GFNHDNMA_01781 2.1e-131 cobQ S glutamine amidotransferase
GFNHDNMA_01782 4.4e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GFNHDNMA_01783 9.8e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
GFNHDNMA_01784 6.1e-185 scrR K Transcriptional regulator, LacI family
GFNHDNMA_01785 1.6e-298 scrB 3.2.1.26 GH32 G invertase
GFNHDNMA_01786 0.0 scrA 2.7.1.199, 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
GFNHDNMA_01787 6.5e-165 L Transposase
GFNHDNMA_01788 6.3e-30 2.7.1.191 G PTS system fructose IIA component
GFNHDNMA_01789 3e-147 agaS M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
GFNHDNMA_01790 3.4e-117 M SIS domain
GFNHDNMA_01791 7e-110 G PTS system mannose/fructose/sorbose family IID component
GFNHDNMA_01792 2.5e-110 G PTS system sorbose-specific iic component
GFNHDNMA_01793 4.1e-59 G PTS system sorbose subfamily IIB component
GFNHDNMA_01794 5.6e-60 K DNA-binding transcription factor activity
GFNHDNMA_01795 2.7e-41 K UTRA
GFNHDNMA_01796 2.4e-101 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GFNHDNMA_01797 4.3e-26 L Transposase
GFNHDNMA_01798 5.1e-120 L Transposase
GFNHDNMA_01799 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GFNHDNMA_01800 6.5e-182 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GFNHDNMA_01801 3.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
GFNHDNMA_01802 1.3e-218 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
GFNHDNMA_01814 5.9e-61
GFNHDNMA_01831 2.8e-25
GFNHDNMA_01832 1.1e-48 XK27_01125 L PFAM IS66 Orf2 family protein
GFNHDNMA_01833 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
GFNHDNMA_01834 5.1e-34 copZ C Heavy-metal-associated domain
GFNHDNMA_01835 1e-93 dps P Belongs to the Dps family
GFNHDNMA_01836 4e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
GFNHDNMA_01837 4.6e-24 ung2 3.2.2.27 L Uracil-DNA glycosylase
GFNHDNMA_01838 2.7e-191 V Beta-lactamase
GFNHDNMA_01839 3.2e-152 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
GFNHDNMA_01840 3e-156 3.6.4.12 S PD-(D/E)XK nuclease family transposase
GFNHDNMA_01841 5.2e-31
GFNHDNMA_01842 2.2e-41
GFNHDNMA_01845 2.7e-21 NU Mycoplasma protein of unknown function, DUF285
GFNHDNMA_01847 7.9e-278 L Transposase
GFNHDNMA_01848 2.6e-41 L Helix-turn-helix domain
GFNHDNMA_01849 3.1e-102 L PFAM Integrase catalytic region

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)