ORF_ID e_value Gene_name EC_number CAZy COGs Description
NAPPIDPI_00001 1e-13 rpmH J Ribosomal protein L34
NAPPIDPI_00002 2e-186 jag S RNA-binding protein
NAPPIDPI_00003 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NAPPIDPI_00004 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NAPPIDPI_00005 5.4e-264 argH 4.3.2.1 E Argininosuccinate lyase
NAPPIDPI_00006 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NAPPIDPI_00007 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NAPPIDPI_00008 6.7e-81 amiA E transmembrane transport
NAPPIDPI_00009 7.3e-69 amiA E transmembrane transport
NAPPIDPI_00010 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NAPPIDPI_00011 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NAPPIDPI_00012 9.2e-51 S Protein of unknown function (DUF3397)
NAPPIDPI_00013 2.3e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NAPPIDPI_00014 1.1e-57 WQ51_05710 S Mitochondrial biogenesis AIM24
NAPPIDPI_00015 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
NAPPIDPI_00016 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NAPPIDPI_00017 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NAPPIDPI_00018 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
NAPPIDPI_00019 4.3e-77 XK27_09620 S reductase
NAPPIDPI_00020 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
NAPPIDPI_00021 3.1e-115 XK27_09615 C reductase
NAPPIDPI_00022 3.2e-62 fnt P Formate nitrite transporter
NAPPIDPI_00023 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
NAPPIDPI_00024 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NAPPIDPI_00025 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NAPPIDPI_00026 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NAPPIDPI_00027 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NAPPIDPI_00028 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NAPPIDPI_00029 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NAPPIDPI_00030 2.7e-48 S glycolate biosynthetic process
NAPPIDPI_00031 3.4e-64 S phosphatase activity
NAPPIDPI_00032 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
NAPPIDPI_00035 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NAPPIDPI_00036 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NAPPIDPI_00037 4.1e-36 yeeD O sulfur carrier activity
NAPPIDPI_00038 4e-187 yeeE S Sulphur transport
NAPPIDPI_00039 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NAPPIDPI_00040 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NAPPIDPI_00041 4.1e-09 S Domain of unknown function (DUF4651)
NAPPIDPI_00042 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NAPPIDPI_00043 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NAPPIDPI_00044 1.8e-111 S CAAX amino terminal protease family protein
NAPPIDPI_00046 5e-67 V CAAX protease self-immunity
NAPPIDPI_00047 1.4e-33 V CAAX protease self-immunity
NAPPIDPI_00048 8.8e-27 lanR K sequence-specific DNA binding
NAPPIDPI_00049 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NAPPIDPI_00050 5.9e-177 ytxK 2.1.1.72 L DNA methylase
NAPPIDPI_00051 2e-12 comGF U Putative Competence protein ComGF
NAPPIDPI_00052 1.5e-71 comGF U Competence protein ComGF
NAPPIDPI_00053 1.4e-15 NU Type II secretory pathway pseudopilin
NAPPIDPI_00054 1.8e-57 cglD NU Competence protein
NAPPIDPI_00055 8.5e-43 comGC U Required for transformation and DNA binding
NAPPIDPI_00056 3e-145 cglB NU type II secretion system
NAPPIDPI_00057 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NAPPIDPI_00058 2.9e-68 S cog cog4699
NAPPIDPI_00059 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAPPIDPI_00060 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAPPIDPI_00061 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NAPPIDPI_00062 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NAPPIDPI_00063 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NAPPIDPI_00064 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
NAPPIDPI_00065 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
NAPPIDPI_00066 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NAPPIDPI_00067 3.3e-11 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NAPPIDPI_00068 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
NAPPIDPI_00069 1.4e-57 asp S cog cog1302
NAPPIDPI_00070 9.3e-226 norN V Mate efflux family protein
NAPPIDPI_00071 2.4e-278 thrC 4.2.3.1 E Threonine synthase
NAPPIDPI_00072 5.5e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NAPPIDPI_00073 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
NAPPIDPI_00074 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NAPPIDPI_00075 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NAPPIDPI_00076 3.1e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
NAPPIDPI_00077 0.0 pepO 3.4.24.71 O Peptidase family M13
NAPPIDPI_00078 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NAPPIDPI_00079 2.5e-64 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NAPPIDPI_00080 2.9e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NAPPIDPI_00081 4.1e-54 treB 2.7.1.201 G PTS System
NAPPIDPI_00082 2.9e-112 treR K trehalose operon
NAPPIDPI_00083 5.7e-95 ywlG S Belongs to the UPF0340 family
NAPPIDPI_00086 3.2e-33 L PFAM Integrase, catalytic core
NAPPIDPI_00087 1.6e-77 sigH K DNA-templated transcription, initiation
NAPPIDPI_00088 3.5e-149 ykuT M mechanosensitive ion channel
NAPPIDPI_00089 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NAPPIDPI_00090 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NAPPIDPI_00091 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NAPPIDPI_00092 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
NAPPIDPI_00093 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
NAPPIDPI_00094 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
NAPPIDPI_00095 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NAPPIDPI_00096 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NAPPIDPI_00097 2.4e-83 nrdI F Belongs to the NrdI family
NAPPIDPI_00098 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NAPPIDPI_00099 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NAPPIDPI_00100 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NAPPIDPI_00101 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NAPPIDPI_00102 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NAPPIDPI_00103 1.9e-45 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NAPPIDPI_00104 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NAPPIDPI_00105 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NAPPIDPI_00106 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NAPPIDPI_00107 6.5e-202 yhjX P Major Facilitator
NAPPIDPI_00108 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NAPPIDPI_00109 5e-94 V VanZ like family
NAPPIDPI_00112 1e-123 glnQ E abc transporter atp-binding protein
NAPPIDPI_00113 1.8e-276 glnP P ABC transporter
NAPPIDPI_00114 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NAPPIDPI_00115 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NAPPIDPI_00116 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
NAPPIDPI_00117 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NAPPIDPI_00118 6.3e-235 sufD O assembly protein SufD
NAPPIDPI_00119 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NAPPIDPI_00120 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
NAPPIDPI_00121 3.5e-274 sufB O assembly protein SufB
NAPPIDPI_00122 7e-10 oppA E ABC transporter substrate-binding protein
NAPPIDPI_00123 2e-138 oppA E ABC transporter substrate-binding protein
NAPPIDPI_00124 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NAPPIDPI_00125 5.3e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NAPPIDPI_00126 1.6e-73 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NAPPIDPI_00127 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NAPPIDPI_00128 3e-27 oppD P Belongs to the ABC transporter superfamily
NAPPIDPI_00129 2.5e-32 oppD P Belongs to the ABC transporter superfamily
NAPPIDPI_00130 1.2e-62 oppD P Belongs to the ABC transporter superfamily
NAPPIDPI_00131 3.1e-43 oppD P Belongs to the ABC transporter superfamily
NAPPIDPI_00132 5.8e-169 oppF P Belongs to the ABC transporter superfamily
NAPPIDPI_00135 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NAPPIDPI_00136 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NAPPIDPI_00137 1.9e-223 EGP Major facilitator Superfamily
NAPPIDPI_00138 3.1e-72 adcR K transcriptional
NAPPIDPI_00139 6.4e-136 adcC P ABC transporter, ATP-binding protein
NAPPIDPI_00140 2.5e-128 adcB P ABC transporter (Permease
NAPPIDPI_00141 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NAPPIDPI_00142 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
NAPPIDPI_00143 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
NAPPIDPI_00144 1.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NAPPIDPI_00145 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
NAPPIDPI_00146 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
NAPPIDPI_00147 1.9e-127 yeeN K transcriptional regulatory protein
NAPPIDPI_00148 9.8e-50 yajC U protein transport
NAPPIDPI_00149 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NAPPIDPI_00150 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
NAPPIDPI_00151 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NAPPIDPI_00152 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NAPPIDPI_00153 0.0 WQ51_06230 S ABC transporter substrate binding protein
NAPPIDPI_00154 5.2e-142 cmpC S abc transporter atp-binding protein
NAPPIDPI_00155 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NAPPIDPI_00156 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NAPPIDPI_00157 1.2e-123 tnp L DDE domain
NAPPIDPI_00158 1.9e-90 L Phage integrase family
NAPPIDPI_00159 2.2e-97 S Stage II sporulation protein M
NAPPIDPI_00160 6.3e-33
NAPPIDPI_00161 7.1e-123 3.1.21.3 V type I restriction modification DNA specificity domain protein
NAPPIDPI_00162 5.1e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
NAPPIDPI_00163 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
NAPPIDPI_00164 5.5e-84 glcU U Glucose uptake
NAPPIDPI_00165 4e-41 glcU U Glucose uptake
NAPPIDPI_00166 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
NAPPIDPI_00167 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
NAPPIDPI_00168 1.6e-77 XK27_10720 D peptidase activity
NAPPIDPI_00169 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
NAPPIDPI_00170 1.7e-08
NAPPIDPI_00172 2.1e-172 yeiH S Membrane
NAPPIDPI_00173 1.6e-118 mur1 NU muramidase
NAPPIDPI_00174 4.5e-166 cpsY K Transcriptional regulator
NAPPIDPI_00175 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NAPPIDPI_00176 1.2e-57 phnA P Alkylphosphonate utilization operon protein PhnA
NAPPIDPI_00177 2e-104 artQ P ABC transporter (Permease
NAPPIDPI_00178 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
NAPPIDPI_00179 1.1e-158 aatB ET ABC transporter substrate-binding protein
NAPPIDPI_00180 1.7e-40 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NAPPIDPI_00181 1.1e-31 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NAPPIDPI_00182 1.6e-65 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NAPPIDPI_00183 2.1e-07
NAPPIDPI_00184 2.3e-62 adhP 1.1.1.1 C alcohol dehydrogenase
NAPPIDPI_00185 1.2e-70 adhP 1.1.1.1 C alcohol dehydrogenase
NAPPIDPI_00186 8.8e-21
NAPPIDPI_00187 0.0 res_1 3.1.21.5 S Type III restriction
NAPPIDPI_00188 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
NAPPIDPI_00189 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NAPPIDPI_00190 2e-126 gntR1 K transcriptional
NAPPIDPI_00191 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NAPPIDPI_00192 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NAPPIDPI_00193 2.4e-87 niaX
NAPPIDPI_00194 7.8e-91 niaR S small molecule binding protein (contains 3H domain)
NAPPIDPI_00195 1.6e-128 K DNA-binding helix-turn-helix protein
NAPPIDPI_00196 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NAPPIDPI_00197 2e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NAPPIDPI_00198 4.1e-167 GK ROK family
NAPPIDPI_00199 8.3e-159 dprA LU DNA protecting protein DprA
NAPPIDPI_00200 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NAPPIDPI_00201 1.4e-150 S TraX protein
NAPPIDPI_00202 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NAPPIDPI_00203 1.3e-252 T PhoQ Sensor
NAPPIDPI_00204 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NAPPIDPI_00205 4.2e-152 XK27_05470 E Methionine synthase
NAPPIDPI_00206 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NAPPIDPI_00207 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NAPPIDPI_00208 6e-43 IQ Acetoin reductase
NAPPIDPI_00209 3.9e-19 IQ Acetoin reductase
NAPPIDPI_00210 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NAPPIDPI_00211 5.2e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NAPPIDPI_00214 1.1e-212 pqqE C radical SAM domain protein
NAPPIDPI_00215 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
NAPPIDPI_00216 6.6e-61 EGP Major facilitator Superfamily
NAPPIDPI_00217 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NAPPIDPI_00218 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NAPPIDPI_00219 2.2e-111 L Transposase
NAPPIDPI_00220 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
NAPPIDPI_00221 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NAPPIDPI_00224 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NAPPIDPI_00225 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NAPPIDPI_00226 1.1e-83 S Putative small multi-drug export protein
NAPPIDPI_00227 6.2e-76 ctsR K Belongs to the CtsR family
NAPPIDPI_00228 0.0 clpC O Belongs to the ClpA ClpB family
NAPPIDPI_00229 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NAPPIDPI_00230 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NAPPIDPI_00231 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NAPPIDPI_00232 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NAPPIDPI_00233 8.7e-105 S SseB protein N-terminal domain
NAPPIDPI_00234 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
NAPPIDPI_00235 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NAPPIDPI_00236 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NAPPIDPI_00239 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NAPPIDPI_00240 3.5e-91 yacP S RNA-binding protein containing a PIN domain
NAPPIDPI_00241 3.4e-155 degV S DegV family
NAPPIDPI_00242 1.8e-31 K helix-turn-helix
NAPPIDPI_00243 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NAPPIDPI_00244 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NAPPIDPI_00245 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NAPPIDPI_00246 1.5e-35 K sequence-specific DNA binding
NAPPIDPI_00248 0.0 S Lantibiotic dehydratase, C terminus
NAPPIDPI_00249 2.4e-231 spaC2 V Lanthionine synthetase C family protein
NAPPIDPI_00250 4.3e-183 EGP Major facilitator Superfamily
NAPPIDPI_00251 5.9e-24 3.6.4.12
NAPPIDPI_00252 5.9e-91 3.6.4.12 K Divergent AAA domain protein
NAPPIDPI_00253 7.4e-225 int L Belongs to the 'phage' integrase family
NAPPIDPI_00254 1.8e-38 S Helix-turn-helix domain
NAPPIDPI_00255 4.9e-173
NAPPIDPI_00257 3.4e-75 isp2 S pathogenesis
NAPPIDPI_00258 5.7e-91 tnp L Transposase
NAPPIDPI_00259 3.3e-225 capA M Bacterial capsule synthesis protein
NAPPIDPI_00260 3.6e-39 gcvR T UPF0237 protein
NAPPIDPI_00261 1.9e-242 XK27_08635 S UPF0210 protein
NAPPIDPI_00262 2e-38 ais G alpha-ribazole phosphatase activity
NAPPIDPI_00263 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NAPPIDPI_00264 1.3e-102 acmA 3.2.1.17 NU amidase activity
NAPPIDPI_00265 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NAPPIDPI_00266 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NAPPIDPI_00267 9.8e-298 dnaK O Heat shock 70 kDa protein
NAPPIDPI_00268 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NAPPIDPI_00269 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NAPPIDPI_00270 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NAPPIDPI_00271 1.7e-60 hmpT S membrane
NAPPIDPI_00272 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NAPPIDPI_00273 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NAPPIDPI_00274 0.0 dnaE 2.7.7.7 L DNA polymerase
NAPPIDPI_00275 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
NAPPIDPI_00276 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NAPPIDPI_00277 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NAPPIDPI_00278 2.5e-43 ysdA L Membrane
NAPPIDPI_00279 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NAPPIDPI_00280 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NAPPIDPI_00281 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NAPPIDPI_00282 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
NAPPIDPI_00284 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NAPPIDPI_00285 2.1e-84 ypmS S Protein conserved in bacteria
NAPPIDPI_00286 6e-144 ypmR E lipolytic protein G-D-S-L family
NAPPIDPI_00287 1e-148 DegV S DegV family
NAPPIDPI_00288 2.6e-217 recN L May be involved in recombinational repair of damaged DNA
NAPPIDPI_00289 1.6e-80 recN L May be involved in recombinational repair of damaged DNA
NAPPIDPI_00290 1.8e-72 argR K Regulates arginine biosynthesis genes
NAPPIDPI_00291 4.3e-158 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NAPPIDPI_00292 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NAPPIDPI_00293 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
NAPPIDPI_00294 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NAPPIDPI_00297 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NAPPIDPI_00298 2.9e-125 dnaD
NAPPIDPI_00299 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NAPPIDPI_00300 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NAPPIDPI_00301 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NAPPIDPI_00302 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NAPPIDPI_00303 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NAPPIDPI_00304 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NAPPIDPI_00305 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NAPPIDPI_00306 5.6e-240 rodA D Belongs to the SEDS family
NAPPIDPI_00307 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
NAPPIDPI_00308 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NAPPIDPI_00309 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NAPPIDPI_00310 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NAPPIDPI_00311 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NAPPIDPI_00312 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NAPPIDPI_00313 1.2e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NAPPIDPI_00314 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NAPPIDPI_00315 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NAPPIDPI_00316 4.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NAPPIDPI_00318 6.6e-31 L Integrase core domain protein
NAPPIDPI_00326 5.3e-11
NAPPIDPI_00332 5.5e-139 mreC M Involved in formation and maintenance of cell shape
NAPPIDPI_00333 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NAPPIDPI_00334 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
NAPPIDPI_00335 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NAPPIDPI_00336 2.9e-218 araT 2.6.1.1 E Aminotransferase
NAPPIDPI_00337 2.4e-124 recO L Involved in DNA repair and RecF pathway recombination
NAPPIDPI_00338 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NAPPIDPI_00339 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NAPPIDPI_00340 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NAPPIDPI_00341 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NAPPIDPI_00342 3.8e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NAPPIDPI_00343 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NAPPIDPI_00344 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NAPPIDPI_00345 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NAPPIDPI_00346 2.3e-90 L transposase activity
NAPPIDPI_00347 3.5e-50 L transposition
NAPPIDPI_00348 2e-32 L Integrase core domain protein
NAPPIDPI_00349 2.3e-161 S CHAP domain
NAPPIDPI_00350 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
NAPPIDPI_00351 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NAPPIDPI_00352 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NAPPIDPI_00353 9.2e-141 1.1.1.169 H Ketopantoate reductase
NAPPIDPI_00354 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NAPPIDPI_00355 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NAPPIDPI_00356 8.2e-70 argR K Regulates arginine biosynthesis genes
NAPPIDPI_00357 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NAPPIDPI_00358 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NAPPIDPI_00359 1.9e-80 S Protein of unknown function (DUF3021)
NAPPIDPI_00360 6.5e-63 KT phosphorelay signal transduction system
NAPPIDPI_00362 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NAPPIDPI_00364 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NAPPIDPI_00365 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
NAPPIDPI_00366 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
NAPPIDPI_00367 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NAPPIDPI_00368 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
NAPPIDPI_00369 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NAPPIDPI_00370 7.9e-39 ptsH G phosphocarrier protein Hpr
NAPPIDPI_00371 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
NAPPIDPI_00372 4.3e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
NAPPIDPI_00373 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NAPPIDPI_00374 2.2e-34 nrdH O Glutaredoxin
NAPPIDPI_00375 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NAPPIDPI_00376 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NAPPIDPI_00378 4.2e-71 L Transposase (IS116 IS110 IS902 family)
NAPPIDPI_00379 5.1e-27 L Transposase (IS116 IS110 IS902 family)
NAPPIDPI_00380 5.8e-164 ypuA S secreted protein
NAPPIDPI_00381 3.4e-70 yaeR E COG0346 Lactoylglutathione lyase and related lyases
NAPPIDPI_00382 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
NAPPIDPI_00383 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NAPPIDPI_00384 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NAPPIDPI_00385 3.4e-258 noxE P NADH oxidase
NAPPIDPI_00386 1.9e-294 yfmM S abc transporter atp-binding protein
NAPPIDPI_00387 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
NAPPIDPI_00388 3.3e-84 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NAPPIDPI_00389 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NAPPIDPI_00390 2e-86 S ECF-type riboflavin transporter, S component
NAPPIDPI_00392 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NAPPIDPI_00393 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
NAPPIDPI_00396 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NAPPIDPI_00397 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NAPPIDPI_00398 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NAPPIDPI_00399 0.0 smc D Required for chromosome condensation and partitioning
NAPPIDPI_00400 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NAPPIDPI_00401 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NAPPIDPI_00402 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NAPPIDPI_00403 2.4e-92 pat 2.3.1.183 M acetyltransferase
NAPPIDPI_00404 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NAPPIDPI_00405 4.4e-123 comFC S Competence protein
NAPPIDPI_00406 1.8e-253 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NAPPIDPI_00407 6.3e-111 yvyE 3.4.13.9 S YigZ family
NAPPIDPI_00408 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NAPPIDPI_00409 3.3e-43 acuB S IMP dehydrogenase activity
NAPPIDPI_00410 2.8e-70 acuB S IMP dehydrogenase activity
NAPPIDPI_00411 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NAPPIDPI_00412 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NAPPIDPI_00413 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
NAPPIDPI_00414 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
NAPPIDPI_00415 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NAPPIDPI_00416 7.1e-46 ylbG S UPF0298 protein
NAPPIDPI_00417 3.4e-74 ylbF S Belongs to the UPF0342 family
NAPPIDPI_00418 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NAPPIDPI_00419 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NAPPIDPI_00422 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NAPPIDPI_00423 1e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
NAPPIDPI_00424 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
NAPPIDPI_00425 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
NAPPIDPI_00426 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NAPPIDPI_00427 8e-213 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NAPPIDPI_00428 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
NAPPIDPI_00429 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
NAPPIDPI_00430 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NAPPIDPI_00431 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NAPPIDPI_00432 1.4e-41 ylxQ J ribosomal protein
NAPPIDPI_00433 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
NAPPIDPI_00434 3.1e-212 nusA K Participates in both transcription termination and antitermination
NAPPIDPI_00435 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
NAPPIDPI_00436 2.5e-220 brpA K Transcriptional
NAPPIDPI_00437 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
NAPPIDPI_00438 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
NAPPIDPI_00439 1.2e-247 pbuO S permease
NAPPIDPI_00440 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NAPPIDPI_00441 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
NAPPIDPI_00442 1.1e-181 manL 2.7.1.191 G pts system
NAPPIDPI_00443 1.7e-116 manM G pts system
NAPPIDPI_00444 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
NAPPIDPI_00445 6.5e-63 manO S protein conserved in bacteria
NAPPIDPI_00446 1.1e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NAPPIDPI_00447 4.5e-36 L transposase activity
NAPPIDPI_00448 3.6e-88 T PhoQ Sensor
NAPPIDPI_00449 2.2e-43 T PhoQ Sensor
NAPPIDPI_00450 2.8e-40 T PhoQ Sensor
NAPPIDPI_00451 2.6e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NAPPIDPI_00452 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NAPPIDPI_00453 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
NAPPIDPI_00454 5.7e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NAPPIDPI_00455 1.7e-94 panT S ECF transporter, substrate-specific component
NAPPIDPI_00456 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NAPPIDPI_00457 7.3e-166 metF 1.5.1.20 C reductase
NAPPIDPI_00458 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NAPPIDPI_00460 2.9e-218 sip L Belongs to the 'phage' integrase family
NAPPIDPI_00461 2.9e-21 xre K transcriptional
NAPPIDPI_00462 1.8e-19 K Cro/C1-type HTH DNA-binding domain
NAPPIDPI_00466 1.4e-13
NAPPIDPI_00467 6.9e-22
NAPPIDPI_00468 3e-164 KL Phage plasmid primase P4 family
NAPPIDPI_00469 2e-296 S DNA primase
NAPPIDPI_00471 2.3e-12
NAPPIDPI_00473 2e-103
NAPPIDPI_00474 1.4e-66 S tRNA_anti-like
NAPPIDPI_00475 4e-22 L Belongs to the 'phage' integrase family
NAPPIDPI_00476 3e-44 ymbI L transposase activity
NAPPIDPI_00477 2.6e-72 hpaIIR 3.1.21.4 L HpaII restriction endonuclease
NAPPIDPI_00478 1.7e-146 2.1.1.37 H cytosine-specific methyltransferase
NAPPIDPI_00479 4.7e-71 V Abi-like protein
NAPPIDPI_00480 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
NAPPIDPI_00481 0.0 3.6.3.8 P cation transport ATPase
NAPPIDPI_00482 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
NAPPIDPI_00483 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NAPPIDPI_00484 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
NAPPIDPI_00485 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NAPPIDPI_00486 0.0 uup S abc transporter atp-binding protein
NAPPIDPI_00488 1.4e-130 pip 1.11.1.10 S Alpha beta hydrolase
NAPPIDPI_00489 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NAPPIDPI_00490 1.5e-100 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NAPPIDPI_00491 8.7e-150 cobQ S glutamine amidotransferase
NAPPIDPI_00492 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
NAPPIDPI_00493 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NAPPIDPI_00494 6e-169 ybbR S Protein conserved in bacteria
NAPPIDPI_00495 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NAPPIDPI_00496 1.7e-70 gtrA S GtrA-like protein
NAPPIDPI_00497 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NAPPIDPI_00498 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NAPPIDPI_00499 6.3e-101 zupT P Mediates zinc uptake. May also transport other divalent cations
NAPPIDPI_00500 1.1e-206 yurR 1.4.5.1 E oxidoreductase
NAPPIDPI_00501 4.1e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NAPPIDPI_00502 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NAPPIDPI_00503 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NAPPIDPI_00506 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
NAPPIDPI_00507 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
NAPPIDPI_00508 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NAPPIDPI_00509 1.1e-121 ylfI S tigr01906
NAPPIDPI_00510 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NAPPIDPI_00511 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NAPPIDPI_00512 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NAPPIDPI_00513 1.3e-22 XK27_08085
NAPPIDPI_00514 1.2e-32 L Integrase core domain protein
NAPPIDPI_00515 1.4e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NAPPIDPI_00516 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NAPPIDPI_00517 3.9e-237 dltB M Membrane protein involved in D-alanine export
NAPPIDPI_00518 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NAPPIDPI_00519 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
NAPPIDPI_00520 0.0 XK27_10035 V abc transporter atp-binding protein
NAPPIDPI_00521 0.0 yfiB1 V abc transporter atp-binding protein
NAPPIDPI_00522 6.6e-105 pvaA M lytic transglycosylase activity
NAPPIDPI_00523 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
NAPPIDPI_00524 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NAPPIDPI_00525 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NAPPIDPI_00526 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NAPPIDPI_00527 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NAPPIDPI_00528 2.4e-112 tdk 2.7.1.21 F thymidine kinase
NAPPIDPI_00529 2.1e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NAPPIDPI_00530 3.1e-155 gst O Glutathione S-transferase
NAPPIDPI_00531 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
NAPPIDPI_00532 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NAPPIDPI_00533 2e-45 rpmE2 J 50S ribosomal protein L31
NAPPIDPI_00534 7.9e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
NAPPIDPI_00535 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NAPPIDPI_00536 1.8e-135 divIVA D Cell division protein DivIVA
NAPPIDPI_00537 6.1e-143 ylmH T S4 RNA-binding domain
NAPPIDPI_00538 2e-34 yggT D integral membrane protein
NAPPIDPI_00539 1.4e-96 sepF D cell septum assembly
NAPPIDPI_00540 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NAPPIDPI_00541 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NAPPIDPI_00542 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NAPPIDPI_00543 2.8e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NAPPIDPI_00544 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NAPPIDPI_00545 4.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NAPPIDPI_00547 6.3e-154 typA T GTP-binding protein TypA
NAPPIDPI_00548 1.5e-178 typA T GTP-binding protein TypA
NAPPIDPI_00549 2.2e-179 glk 2.7.1.2 G Glucokinase
NAPPIDPI_00550 8.4e-28 yqgQ S protein conserved in bacteria
NAPPIDPI_00551 1.1e-80 perR P Belongs to the Fur family
NAPPIDPI_00552 3.5e-91 dps P Belongs to the Dps family
NAPPIDPI_00553 2.2e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NAPPIDPI_00554 2e-186 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
NAPPIDPI_00555 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
NAPPIDPI_00556 1.3e-134 holA 2.7.7.7 L DNA polymerase III delta subunit
NAPPIDPI_00557 1.5e-37 holA 2.7.7.7 L DNA polymerase III delta subunit
NAPPIDPI_00558 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NAPPIDPI_00559 6.2e-56 S Domain of unknown function (DUF4430)
NAPPIDPI_00560 4.2e-75 S Psort location CytoplasmicMembrane, score
NAPPIDPI_00561 4.2e-132 htpX O Belongs to the peptidase M48B family
NAPPIDPI_00562 1.5e-92 lemA S LemA family
NAPPIDPI_00563 3.4e-175 spd F DNA RNA non-specific endonuclease
NAPPIDPI_00564 1.1e-190 higA K Pfam:DUF955
NAPPIDPI_00565 1.2e-33
NAPPIDPI_00566 1.4e-10 endA F DNA/RNA non-specific endonuclease
NAPPIDPI_00567 2.6e-92 pcrA1 3.6.4.12 L UvrD/REP helicase N-terminal domain
NAPPIDPI_00568 9.5e-149 L Protein of unknown function (DUF2813)
NAPPIDPI_00569 1e-146 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
NAPPIDPI_00570 5.6e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
NAPPIDPI_00571 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
NAPPIDPI_00572 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
NAPPIDPI_00573 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
NAPPIDPI_00574 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NAPPIDPI_00575 2.1e-27 P Hemerythrin HHE cation binding domain protein
NAPPIDPI_00576 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
NAPPIDPI_00577 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NAPPIDPI_00578 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NAPPIDPI_00579 7.5e-174 S hydrolase
NAPPIDPI_00580 7.6e-16
NAPPIDPI_00581 1e-163 M LysM domain
NAPPIDPI_00582 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NAPPIDPI_00583 0.0 L helicase
NAPPIDPI_00584 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
NAPPIDPI_00585 2.1e-11
NAPPIDPI_00586 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
NAPPIDPI_00587 1.1e-33 XK27_12190 S protein conserved in bacteria
NAPPIDPI_00589 8.4e-88 bioY S biotin synthase
NAPPIDPI_00590 8.1e-46 S CHY zinc finger
NAPPIDPI_00591 7.5e-252 yegQ O Peptidase U32
NAPPIDPI_00592 2e-177 yegQ O Peptidase U32
NAPPIDPI_00594 5.5e-69 ytxH S General stress protein
NAPPIDPI_00596 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NAPPIDPI_00597 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NAPPIDPI_00598 9.9e-42 pspC KT PspC domain
NAPPIDPI_00599 0.0 yhgF K Transcriptional accessory protein
NAPPIDPI_00601 1.2e-155 XK27_03015 S permease
NAPPIDPI_00602 2.7e-146 ycgQ S TIGR03943 family
NAPPIDPI_00603 1e-185 S CRISPR-associated protein Csn2 subfamily St
NAPPIDPI_00604 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAPPIDPI_00605 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAPPIDPI_00606 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NAPPIDPI_00607 1.1e-94
NAPPIDPI_00608 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
NAPPIDPI_00609 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
NAPPIDPI_00610 1e-31 K Cro/C1-type HTH DNA-binding domain
NAPPIDPI_00611 4.7e-106
NAPPIDPI_00612 1.3e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NAPPIDPI_00613 4.5e-97 mip S hydroperoxide reductase activity
NAPPIDPI_00614 2.4e-203 I acyl-CoA dehydrogenase
NAPPIDPI_00615 4.3e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
NAPPIDPI_00616 9e-238 msrR K Transcriptional regulator
NAPPIDPI_00617 2.5e-152 pheA 4.2.1.51 E Prephenate dehydratase
NAPPIDPI_00618 2.5e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NAPPIDPI_00619 8.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NAPPIDPI_00620 8.8e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NAPPIDPI_00621 3.2e-53 yheA S Belongs to the UPF0342 family
NAPPIDPI_00622 1.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NAPPIDPI_00623 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NAPPIDPI_00624 2.9e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NAPPIDPI_00625 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NAPPIDPI_00626 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NAPPIDPI_00627 2e-219 ywbD 2.1.1.191 J Methyltransferase
NAPPIDPI_00628 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NAPPIDPI_00630 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NAPPIDPI_00631 1e-78 yueI S Protein of unknown function (DUF1694)
NAPPIDPI_00632 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NAPPIDPI_00633 6.6e-101 yyaQ V Protein conserved in bacteria
NAPPIDPI_00634 2.8e-28 yyaQ S YjbR
NAPPIDPI_00635 4.4e-183 ccpA K Catabolite control protein A
NAPPIDPI_00636 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
NAPPIDPI_00637 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
NAPPIDPI_00638 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NAPPIDPI_00639 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NAPPIDPI_00640 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NAPPIDPI_00641 2e-33 secG U Preprotein translocase subunit SecG
NAPPIDPI_00642 9.5e-74 mdtG EGP Major facilitator Superfamily
NAPPIDPI_00643 6e-133 mdtG EGP Major facilitator Superfamily
NAPPIDPI_00644 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NAPPIDPI_00645 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NAPPIDPI_00646 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NAPPIDPI_00647 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NAPPIDPI_00648 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NAPPIDPI_00649 6.8e-53 licT K transcriptional antiterminator
NAPPIDPI_00650 9.2e-43 licT K transcriptional antiterminator
NAPPIDPI_00652 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NAPPIDPI_00653 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
NAPPIDPI_00654 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NAPPIDPI_00655 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NAPPIDPI_00656 7.5e-23 I Alpha/beta hydrolase family
NAPPIDPI_00657 1.5e-35 yugF I carboxylic ester hydrolase activity
NAPPIDPI_00658 1.5e-07
NAPPIDPI_00659 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NAPPIDPI_00660 1.1e-78 feoA P FeoA domain protein
NAPPIDPI_00661 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
NAPPIDPI_00662 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
NAPPIDPI_00664 1.3e-34 ykuJ S protein conserved in bacteria
NAPPIDPI_00665 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NAPPIDPI_00666 2.6e-221 clpE O Belongs to the ClpA ClpB family
NAPPIDPI_00667 2e-135 clpE O Belongs to the ClpA ClpB family
NAPPIDPI_00668 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NAPPIDPI_00669 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
NAPPIDPI_00670 9.7e-66 S oxidoreductase
NAPPIDPI_00671 9.3e-59 S oxidoreductase
NAPPIDPI_00672 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
NAPPIDPI_00673 6.1e-70 M Pfam SNARE associated Golgi protein
NAPPIDPI_00674 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
NAPPIDPI_00677 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
NAPPIDPI_00680 4.8e-16 S Protein of unknown function (DUF2969)
NAPPIDPI_00681 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
NAPPIDPI_00682 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NAPPIDPI_00683 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NAPPIDPI_00684 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NAPPIDPI_00685 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
NAPPIDPI_00686 1.4e-29 S Domain of unknown function (DUF1912)
NAPPIDPI_00687 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
NAPPIDPI_00688 3.2e-248 mmuP E amino acid
NAPPIDPI_00689 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NAPPIDPI_00690 9.8e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NAPPIDPI_00691 9.7e-22
NAPPIDPI_00692 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NAPPIDPI_00693 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NAPPIDPI_00694 5e-218 mvaS 2.3.3.10 I synthase
NAPPIDPI_00695 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NAPPIDPI_00696 1e-25 K hmm pf08876
NAPPIDPI_00697 5.4e-116 yqfA K protein, Hemolysin III
NAPPIDPI_00698 3.6e-22 S Protein of unknown function (DUF3114)
NAPPIDPI_00699 2.3e-164 S Protein of unknown function (DUF3114)
NAPPIDPI_00700 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NAPPIDPI_00701 8.9e-57 S hydrolase activity, acting on ester bonds
NAPPIDPI_00702 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NAPPIDPI_00703 4.9e-21 XK27_13030
NAPPIDPI_00704 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NAPPIDPI_00705 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
NAPPIDPI_00706 4.8e-07 U protein secretion
NAPPIDPI_00707 2.7e-50 U protein secretion
NAPPIDPI_00708 3.5e-07 U protein secretion
NAPPIDPI_00710 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NAPPIDPI_00711 2.5e-21
NAPPIDPI_00712 8.5e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
NAPPIDPI_00713 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NAPPIDPI_00714 3.4e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NAPPIDPI_00715 5e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
NAPPIDPI_00716 5.1e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NAPPIDPI_00717 5.3e-140 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NAPPIDPI_00718 1.4e-104 GBS0088 J protein conserved in bacteria
NAPPIDPI_00719 3e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NAPPIDPI_00720 2e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NAPPIDPI_00721 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
NAPPIDPI_00722 8e-221 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NAPPIDPI_00723 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NAPPIDPI_00724 9.6e-113 S VIT family
NAPPIDPI_00725 1.2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
NAPPIDPI_00726 4.3e-22
NAPPIDPI_00727 1e-195 yceA S Belongs to the UPF0176 family
NAPPIDPI_00728 5.4e-122 sagI S ABC-2 type transporter
NAPPIDPI_00729 4.8e-168 V ABC transporter
NAPPIDPI_00730 1.1e-217 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NAPPIDPI_00731 2.1e-131 rr02 KT response regulator
NAPPIDPI_00732 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NAPPIDPI_00733 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NAPPIDPI_00734 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NAPPIDPI_00735 0.0 lmrA V abc transporter atp-binding protein
NAPPIDPI_00736 0.0 mdlB V abc transporter atp-binding protein
NAPPIDPI_00738 1.7e-142 M the current gene model (or a revised gene model) may contain a
NAPPIDPI_00739 2.5e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
NAPPIDPI_00740 3.1e-172 yxaM EGP Major facilitator Superfamily
NAPPIDPI_00741 1.5e-89 adk 2.7.4.3 F topology modulation protein
NAPPIDPI_00742 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NAPPIDPI_00743 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NAPPIDPI_00744 1.7e-35 XK27_09805 S MORN repeat protein
NAPPIDPI_00745 0.0 XK27_09800 I Acyltransferase
NAPPIDPI_00746 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NAPPIDPI_00747 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NAPPIDPI_00748 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NAPPIDPI_00749 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
NAPPIDPI_00750 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NAPPIDPI_00751 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NAPPIDPI_00752 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NAPPIDPI_00753 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NAPPIDPI_00754 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NAPPIDPI_00755 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NAPPIDPI_00756 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
NAPPIDPI_00757 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NAPPIDPI_00758 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NAPPIDPI_00759 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NAPPIDPI_00760 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NAPPIDPI_00761 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NAPPIDPI_00762 1.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NAPPIDPI_00763 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NAPPIDPI_00764 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NAPPIDPI_00765 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NAPPIDPI_00766 2.5e-23 rpmD J ribosomal protein l30
NAPPIDPI_00767 1.3e-57 rplO J binds to the 23S rRNA
NAPPIDPI_00768 5.1e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NAPPIDPI_00769 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NAPPIDPI_00770 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NAPPIDPI_00771 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NAPPIDPI_00772 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NAPPIDPI_00773 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NAPPIDPI_00774 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAPPIDPI_00775 3.3e-62 rplQ J ribosomal protein l17
NAPPIDPI_00776 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NAPPIDPI_00777 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NAPPIDPI_00778 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NAPPIDPI_00779 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NAPPIDPI_00780 1.1e-142 purR 2.4.2.7 F operon repressor
NAPPIDPI_00781 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
NAPPIDPI_00782 4.3e-59 rmuC S RmuC domain protein
NAPPIDPI_00783 1.4e-88 rmuC S RmuC domain protein
NAPPIDPI_00784 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
NAPPIDPI_00785 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NAPPIDPI_00786 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NAPPIDPI_00788 1.7e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NAPPIDPI_00789 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NAPPIDPI_00790 4.1e-144 tatD L Hydrolase, tatd
NAPPIDPI_00791 1.9e-74 yccU S CoA-binding protein
NAPPIDPI_00792 4.8e-51 trxA O Belongs to the thioredoxin family
NAPPIDPI_00793 1.9e-141 S Macro domain protein
NAPPIDPI_00794 2e-09 L thioesterase
NAPPIDPI_00795 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
NAPPIDPI_00797 1.5e-07
NAPPIDPI_00798 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NAPPIDPI_00799 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NAPPIDPI_00800 3.1e-81 ypmB S Protein conserved in bacteria
NAPPIDPI_00801 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NAPPIDPI_00802 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NAPPIDPI_00803 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
NAPPIDPI_00804 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
NAPPIDPI_00805 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NAPPIDPI_00806 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NAPPIDPI_00807 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NAPPIDPI_00808 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NAPPIDPI_00809 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NAPPIDPI_00810 6e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NAPPIDPI_00811 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NAPPIDPI_00812 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
NAPPIDPI_00813 4e-104 coaA 2.7.1.33 F Pantothenic acid kinase
NAPPIDPI_00814 2.1e-30 rpsT J rRNA binding
NAPPIDPI_00815 9.8e-163 L Integrase core domain protein
NAPPIDPI_00816 2.3e-106 L Helix-turn-helix domain
NAPPIDPI_00817 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
NAPPIDPI_00818 3.1e-268 clcA P Chloride transporter, ClC family
NAPPIDPI_00819 8.9e-206 potD P spermidine putrescine ABC transporter
NAPPIDPI_00820 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
NAPPIDPI_00821 1.1e-220 L Transposase
NAPPIDPI_00822 3e-13
NAPPIDPI_00823 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
NAPPIDPI_00824 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NAPPIDPI_00825 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NAPPIDPI_00826 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NAPPIDPI_00827 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NAPPIDPI_00828 2.2e-19 D nuclear chromosome segregation
NAPPIDPI_00829 2.8e-137 yejC S cyclic nucleotide-binding protein
NAPPIDPI_00830 1.2e-163 rapZ S Displays ATPase and GTPase activities
NAPPIDPI_00831 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NAPPIDPI_00832 8.7e-162 whiA K May be required for sporulation
NAPPIDPI_00833 6.4e-168 pepD E Dipeptidase
NAPPIDPI_00834 5.4e-32 cspD K Cold shock protein domain
NAPPIDPI_00835 8e-42 K Cold-Shock Protein
NAPPIDPI_00836 2.3e-31 L Integrase core domain protein
NAPPIDPI_00837 1e-96 S reductase
NAPPIDPI_00838 1.7e-54 badR K DNA-binding transcription factor activity
NAPPIDPI_00839 5.5e-36 XK27_02060 S Transglycosylase associated protein
NAPPIDPI_00840 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NAPPIDPI_00841 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NAPPIDPI_00846 1.9e-07
NAPPIDPI_00849 2.6e-10
NAPPIDPI_00854 8.7e-51 M YSIRK type signal peptide
NAPPIDPI_00855 1.1e-40 S MucBP domain
NAPPIDPI_00856 3.2e-19 L COG COG2801 Transposase and inactivated derivatives
NAPPIDPI_00857 1.1e-32 L Integrase core domain
NAPPIDPI_00858 1.7e-35 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NAPPIDPI_00859 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NAPPIDPI_00860 2.4e-27 ytrF V efflux transmembrane transporter activity
NAPPIDPI_00861 1.3e-10 V permease protein
NAPPIDPI_00862 1.3e-25 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NAPPIDPI_00863 2.5e-53 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
NAPPIDPI_00864 3.2e-300 hsdM 2.1.1.72 V HsdM N-terminal domain
NAPPIDPI_00865 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NAPPIDPI_00866 2.4e-26
NAPPIDPI_00867 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NAPPIDPI_00868 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NAPPIDPI_00869 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NAPPIDPI_00870 2.6e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
NAPPIDPI_00871 3.3e-09 L PFAM Integrase, catalytic core
NAPPIDPI_00872 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
NAPPIDPI_00873 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
NAPPIDPI_00874 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
NAPPIDPI_00876 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
NAPPIDPI_00877 1.2e-137 L DNA integration
NAPPIDPI_00878 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NAPPIDPI_00879 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NAPPIDPI_00880 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NAPPIDPI_00881 1.2e-62 bioY S biotin transmembrane transporter activity
NAPPIDPI_00882 2e-88 proW P Binding-protein-dependent transport system inner membrane component
NAPPIDPI_00883 1.6e-137 proV E abc transporter atp-binding protein
NAPPIDPI_00884 1.1e-124 proX M ABC transporter, substrate-binding protein, QAT family
NAPPIDPI_00885 2.3e-103 proWZ P ABC transporter (Permease
NAPPIDPI_00886 7.7e-43 hutH 4.3.1.3 E Histidine ammonia-lyase
NAPPIDPI_00887 1.1e-223 hutH 4.3.1.3 E Histidine ammonia-lyase
NAPPIDPI_00888 1.6e-205 S Protein of unknown function (DUF917)
NAPPIDPI_00889 2.5e-308 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NAPPIDPI_00890 4.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
NAPPIDPI_00891 1.3e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NAPPIDPI_00892 6e-186 desK 2.7.13.3 T Histidine kinase
NAPPIDPI_00893 2.4e-133 yvfS V ABC-2 type transporter
NAPPIDPI_00894 9.7e-158 XK27_09825 V abc transporter atp-binding protein
NAPPIDPI_00898 6.6e-213 EGP Major facilitator Superfamily
NAPPIDPI_00899 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
NAPPIDPI_00900 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
NAPPIDPI_00901 4.6e-42 3.6.1.55 F NUDIX domain
NAPPIDPI_00903 3.7e-122 S An automated process has identified a potential problem with this gene model
NAPPIDPI_00904 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
NAPPIDPI_00905 1.4e-15 liaI KT membrane
NAPPIDPI_00906 2.6e-30 liaI KT membrane
NAPPIDPI_00907 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
NAPPIDPI_00908 0.0 V ABC transporter (permease)
NAPPIDPI_00909 1.9e-133 macB2 V ABC transporter, ATP-binding protein
NAPPIDPI_00910 9e-165 T Histidine kinase
NAPPIDPI_00911 2e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NAPPIDPI_00912 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NAPPIDPI_00913 3.3e-69 pbuX F xanthine permease
NAPPIDPI_00914 9.2e-119 pbuX F xanthine permease
NAPPIDPI_00915 5.6e-26 norM V Multidrug efflux pump
NAPPIDPI_00916 4.8e-213 norM V Multidrug efflux pump
NAPPIDPI_00917 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NAPPIDPI_00918 1.7e-235 brnQ E Component of the transport system for branched-chain amino acids
NAPPIDPI_00919 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
NAPPIDPI_00920 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
NAPPIDPI_00921 4.8e-25 csbD K CsbD-like
NAPPIDPI_00922 8.2e-228 yfnA E amino acid
NAPPIDPI_00923 5.1e-110 XK27_02070 S nitroreductase
NAPPIDPI_00924 9.5e-150 1.13.11.2 S glyoxalase
NAPPIDPI_00925 5.6e-77 ywnA K Transcriptional regulator
NAPPIDPI_00926 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
NAPPIDPI_00927 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NAPPIDPI_00928 1.4e-110 drgA C Nitroreductase
NAPPIDPI_00929 3e-102 yoaK S Protein of unknown function (DUF1275)
NAPPIDPI_00931 6.8e-161 yvgN C reductase
NAPPIDPI_00932 5.7e-180 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NAPPIDPI_00933 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
NAPPIDPI_00935 4.8e-55 K response regulator
NAPPIDPI_00936 2.7e-71 S Signal peptide protein, YSIRK family
NAPPIDPI_00938 3.2e-59
NAPPIDPI_00939 1.7e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NAPPIDPI_00940 1.9e-35
NAPPIDPI_00941 4e-20
NAPPIDPI_00942 3.3e-24 IQ PFAM AMP-dependent synthetase and ligase
NAPPIDPI_00943 2.7e-26 IQ PFAM AMP-dependent synthetase and ligase
NAPPIDPI_00944 5.8e-109 MA20_06410 E LysE type translocator
NAPPIDPI_00945 5.6e-08
NAPPIDPI_00946 2.7e-09
NAPPIDPI_00947 0.0 M family 8
NAPPIDPI_00949 1.5e-162 hrtB V MacB-like periplasmic core domain
NAPPIDPI_00950 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
NAPPIDPI_00951 1.1e-151 V MatE
NAPPIDPI_00953 3.9e-110 C Fe-S oxidoreductases
NAPPIDPI_00954 1.2e-176 EGP Major Facilitator Superfamily
NAPPIDPI_00955 5.5e-258 I radical SAM domain protein
NAPPIDPI_00957 1.7e-81 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NAPPIDPI_00958 4e-66 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NAPPIDPI_00959 1.4e-150 L Integrase core domain protein
NAPPIDPI_00960 1.8e-87 L transposase activity
NAPPIDPI_00962 2.8e-85
NAPPIDPI_00963 0.0 sbcC L ATPase involved in DNA repair
NAPPIDPI_00964 3.8e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NAPPIDPI_00965 0.0 lacL 3.2.1.23 G -beta-galactosidase
NAPPIDPI_00966 0.0 lacS G transporter
NAPPIDPI_00967 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NAPPIDPI_00968 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NAPPIDPI_00969 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NAPPIDPI_00970 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NAPPIDPI_00971 2.3e-184 galR K Transcriptional regulator
NAPPIDPI_00972 2.7e-08 L Integrase core domain protein
NAPPIDPI_00973 1.2e-25 L transposition
NAPPIDPI_00974 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NAPPIDPI_00975 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NAPPIDPI_00976 2.5e-101 V abc transporter atp-binding protein
NAPPIDPI_00977 4.3e-40 V abc transporter atp-binding protein
NAPPIDPI_00978 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NAPPIDPI_00979 6.4e-62 L Transposase
NAPPIDPI_00980 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAPPIDPI_00981 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAPPIDPI_00982 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAPPIDPI_00983 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NAPPIDPI_00984 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NAPPIDPI_00985 7.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NAPPIDPI_00986 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NAPPIDPI_00989 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NAPPIDPI_00990 5.8e-175 vraS 2.7.13.3 T Histidine kinase
NAPPIDPI_00991 3.7e-120 yvqF KT membrane
NAPPIDPI_00992 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NAPPIDPI_00993 2e-132 stp 3.1.3.16 T phosphatase
NAPPIDPI_00994 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NAPPIDPI_00995 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NAPPIDPI_00996 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NAPPIDPI_00997 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
NAPPIDPI_00998 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NAPPIDPI_00999 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NAPPIDPI_01000 6.9e-150 XK27_02985 S overlaps another CDS with the same product name
NAPPIDPI_01001 2.1e-148 supH S overlaps another CDS with the same product name
NAPPIDPI_01002 8.6e-63 yvoA_1 K Transcriptional
NAPPIDPI_01003 2.8e-120 skfE V abc transporter atp-binding protein
NAPPIDPI_01004 5.6e-133 V ATPase activity
NAPPIDPI_01005 1.2e-171 oppF P Belongs to the ABC transporter superfamily
NAPPIDPI_01006 1.4e-203 oppD P Belongs to the ABC transporter superfamily
NAPPIDPI_01007 3.1e-167 amiD P ABC transporter (Permease
NAPPIDPI_01008 1.1e-270 amiC P ABC transporter (Permease
NAPPIDPI_01009 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NAPPIDPI_01010 1.2e-24 oppF P Belongs to the ABC transporter superfamily
NAPPIDPI_01011 1.1e-44 oppF P Belongs to the ABC transporter superfamily
NAPPIDPI_01012 1.4e-40 tatD L Hydrolase, tatd
NAPPIDPI_01013 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
NAPPIDPI_01014 2.1e-85 L Integrase core domain protein
NAPPIDPI_01015 6.6e-79 L Transposase
NAPPIDPI_01016 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NAPPIDPI_01017 8.3e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NAPPIDPI_01018 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NAPPIDPI_01019 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
NAPPIDPI_01020 1.5e-103 yjbK S Adenylate cyclase
NAPPIDPI_01021 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NAPPIDPI_01022 1.2e-205 iscS 2.8.1.7 E Cysteine desulfurase
NAPPIDPI_01023 3.1e-59 XK27_04120 S Putative amino acid metabolism
NAPPIDPI_01024 1.1e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NAPPIDPI_01025 4.8e-128 puuD T peptidase C26
NAPPIDPI_01026 1.2e-115 radC E Belongs to the UPF0758 family
NAPPIDPI_01027 1.7e-268 M Psort location CytoplasmicMembrane, score
NAPPIDPI_01028 0.0 rgpF M Rhamnan synthesis protein F
NAPPIDPI_01029 4.5e-305 GT4 M transferase activity, transferring glycosyl groups
NAPPIDPI_01030 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NAPPIDPI_01031 1.8e-142 rgpC GM Transport permease protein
NAPPIDPI_01032 6.4e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
NAPPIDPI_01033 2.3e-228 rgpA GT4 M Domain of unknown function (DUF1972)
NAPPIDPI_01034 2.4e-152 2.4.1.60 S Glycosyltransferase group 2 family protein
NAPPIDPI_01035 4.6e-42 S Uncharacterized conserved protein (DUF2304)
NAPPIDPI_01036 6.9e-130 arnC M group 2 family protein
NAPPIDPI_01037 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
NAPPIDPI_01038 1e-184 S Glycosyltransferase like family 2
NAPPIDPI_01039 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
NAPPIDPI_01040 2.6e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NAPPIDPI_01041 2e-236 S Predicted membrane protein (DUF2142)
NAPPIDPI_01042 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NAPPIDPI_01043 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
NAPPIDPI_01044 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NAPPIDPI_01045 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NAPPIDPI_01046 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NAPPIDPI_01047 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
NAPPIDPI_01048 2.1e-202 arcT 2.6.1.1 E Aminotransferase
NAPPIDPI_01049 9.4e-136 ET ABC transporter
NAPPIDPI_01050 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
NAPPIDPI_01051 2.9e-84 mutT 3.6.1.55 F Nudix family
NAPPIDPI_01052 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NAPPIDPI_01054 6.9e-79 S CAAX amino terminal protease family protein
NAPPIDPI_01055 7.6e-32 S CAAX amino terminal protease family protein
NAPPIDPI_01056 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NAPPIDPI_01057 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
NAPPIDPI_01058 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NAPPIDPI_01059 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NAPPIDPI_01060 9.9e-19 S Domain of unknown function (DUF4649)
NAPPIDPI_01061 1.1e-36 L Transposase
NAPPIDPI_01063 0.0 copB 3.6.3.4 P P-type ATPase
NAPPIDPI_01064 5e-84 L Transposase
NAPPIDPI_01065 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NAPPIDPI_01067 6.5e-74
NAPPIDPI_01068 3.7e-140 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NAPPIDPI_01069 9.2e-71 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NAPPIDPI_01070 3.6e-165 L integrase core domain
NAPPIDPI_01071 3.9e-122 L Transposase
NAPPIDPI_01072 1.6e-249 L Transposase
NAPPIDPI_01073 4.2e-29 L transposition
NAPPIDPI_01074 1.8e-56 L transposition
NAPPIDPI_01075 9.1e-83 L Integrase core domain protein
NAPPIDPI_01076 3.1e-92 blpT
NAPPIDPI_01077 2.9e-28 blpT
NAPPIDPI_01078 3e-47 spiA K sequence-specific DNA binding
NAPPIDPI_01081 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NAPPIDPI_01082 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NAPPIDPI_01083 5e-44 V CAAX protease self-immunity
NAPPIDPI_01084 4.6e-140 cppA E CppA N-terminal
NAPPIDPI_01085 9.4e-183 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
NAPPIDPI_01086 3.6e-117 ybbL S abc transporter atp-binding protein
NAPPIDPI_01087 1.5e-127 ybbM S transport system, permease component
NAPPIDPI_01088 2.9e-87 D nuclear chromosome segregation
NAPPIDPI_01089 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
NAPPIDPI_01090 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NAPPIDPI_01091 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
NAPPIDPI_01092 0.0 pflB 2.3.1.54 C formate acetyltransferase'
NAPPIDPI_01093 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NAPPIDPI_01095 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NAPPIDPI_01096 4.7e-163 yxeN P ABC transporter (Permease
NAPPIDPI_01097 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
NAPPIDPI_01098 3.2e-09 S Protein of unknown function (DUF4059)
NAPPIDPI_01099 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NAPPIDPI_01100 4.3e-92 rsmD 2.1.1.171 L Methyltransferase
NAPPIDPI_01101 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NAPPIDPI_01102 1.3e-151 ylbL T Belongs to the peptidase S16 family
NAPPIDPI_01103 2.8e-28 ylbL T Belongs to the peptidase S16 family
NAPPIDPI_01104 1.3e-184 yhcC S radical SAM protein
NAPPIDPI_01105 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
NAPPIDPI_01107 0.0 yjcE P NhaP-type Na H and K H antiporters
NAPPIDPI_01108 1.2e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
NAPPIDPI_01109 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
NAPPIDPI_01110 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NAPPIDPI_01113 5.3e-75 XK27_03180 T universal stress protein
NAPPIDPI_01114 4.8e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
NAPPIDPI_01115 2.8e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NAPPIDPI_01116 6.8e-101 pncA Q isochorismatase
NAPPIDPI_01117 4.8e-154 hlpA M Belongs to the NlpA lipoprotein family
NAPPIDPI_01118 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NAPPIDPI_01119 3.6e-257 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NAPPIDPI_01120 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NAPPIDPI_01121 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NAPPIDPI_01122 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NAPPIDPI_01123 1.3e-57
NAPPIDPI_01124 2.1e-89 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NAPPIDPI_01125 5.4e-48 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NAPPIDPI_01126 1.8e-98 yqeG S hydrolase of the HAD superfamily
NAPPIDPI_01127 2.4e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NAPPIDPI_01128 3.5e-49 yhbY J RNA-binding protein
NAPPIDPI_01129 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NAPPIDPI_01130 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NAPPIDPI_01131 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NAPPIDPI_01132 2e-140 yqeM Q Methyltransferase domain protein
NAPPIDPI_01133 1.5e-205 ylbM S Belongs to the UPF0348 family
NAPPIDPI_01134 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
NAPPIDPI_01135 9.2e-110
NAPPIDPI_01136 1.8e-56 S CD20-like family
NAPPIDPI_01137 2.3e-10
NAPPIDPI_01138 1.9e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NAPPIDPI_01139 2.3e-133 ecsA V abc transporter atp-binding protein
NAPPIDPI_01140 1.1e-181 ecsB U ABC transporter
NAPPIDPI_01141 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
NAPPIDPI_01142 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NAPPIDPI_01144 6.1e-57 ytfP S Flavoprotein
NAPPIDPI_01145 2.2e-134 ytfP S Flavoprotein
NAPPIDPI_01146 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NAPPIDPI_01147 1.6e-63 XK27_02560 S cog cog2151
NAPPIDPI_01148 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
NAPPIDPI_01149 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
NAPPIDPI_01150 1.4e-81 K transcriptional regulator, MerR family
NAPPIDPI_01151 5.1e-47 L transposase activity
NAPPIDPI_01152 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NAPPIDPI_01153 3.9e-26
NAPPIDPI_01154 0.0 ctpE P E1-E2 ATPase
NAPPIDPI_01155 1.7e-51
NAPPIDPI_01156 8.1e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
NAPPIDPI_01157 6.9e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NAPPIDPI_01158 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
NAPPIDPI_01159 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NAPPIDPI_01160 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NAPPIDPI_01161 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
NAPPIDPI_01162 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NAPPIDPI_01163 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NAPPIDPI_01164 2.7e-73 copY K Copper transport repressor, CopY TcrY family
NAPPIDPI_01165 0.0 copA 3.6.3.54 P P-type ATPase
NAPPIDPI_01166 2e-29 copZ 2.7.7.77 P Heavy metal-associated domain protein
NAPPIDPI_01167 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NAPPIDPI_01168 1e-114 papP P ABC transporter (Permease
NAPPIDPI_01169 4.6e-115 P ABC transporter (Permease
NAPPIDPI_01170 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
NAPPIDPI_01171 1.1e-155 cjaA ET ABC transporter substrate-binding protein
NAPPIDPI_01175 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NAPPIDPI_01176 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
NAPPIDPI_01177 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NAPPIDPI_01178 6e-175 yjbB G Permeases of the major facilitator superfamily
NAPPIDPI_01179 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NAPPIDPI_01180 7.8e-100 thiT S Thiamine transporter
NAPPIDPI_01181 1.9e-62 yjqA S Bacterial PH domain
NAPPIDPI_01182 2.3e-154 corA P CorA-like protein
NAPPIDPI_01183 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NAPPIDPI_01184 1e-41 yazA L endonuclease containing a URI domain
NAPPIDPI_01185 7.1e-141 yabB 2.1.1.223 L Methyltransferase
NAPPIDPI_01186 1.5e-61 nodB3 G deacetylase
NAPPIDPI_01187 4.4e-73 nodB3 G polysaccharide deacetylase
NAPPIDPI_01188 1.3e-142 plsC 2.3.1.51 I Acyltransferase
NAPPIDPI_01189 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NAPPIDPI_01190 0.0 comEC S Competence protein ComEC
NAPPIDPI_01191 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NAPPIDPI_01192 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NAPPIDPI_01193 3.3e-231 ytoI K transcriptional regulator containing CBS domains
NAPPIDPI_01194 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NAPPIDPI_01195 7.4e-164 rbn E Belongs to the UPF0761 family
NAPPIDPI_01196 3.7e-85 ccl S cog cog4708
NAPPIDPI_01197 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NAPPIDPI_01198 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NAPPIDPI_01199 1.9e-55 L Transposase
NAPPIDPI_01200 2.1e-74 S QueT transporter
NAPPIDPI_01201 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
NAPPIDPI_01202 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
NAPPIDPI_01203 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NAPPIDPI_01204 4.1e-37 ylqC L Belongs to the UPF0109 family
NAPPIDPI_01205 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NAPPIDPI_01206 0.0 ydaO E amino acid
NAPPIDPI_01207 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
NAPPIDPI_01208 4.2e-65 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NAPPIDPI_01209 1.9e-52 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NAPPIDPI_01210 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
NAPPIDPI_01211 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NAPPIDPI_01212 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NAPPIDPI_01213 7.8e-171 murB 1.3.1.98 M cell wall formation
NAPPIDPI_01214 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NAPPIDPI_01215 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
NAPPIDPI_01216 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
NAPPIDPI_01217 2.3e-206 potD P spermidine putrescine ABC transporter
NAPPIDPI_01218 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
NAPPIDPI_01219 9.6e-26 XK27_08050 O HflC and HflK could regulate a protease
NAPPIDPI_01220 6.6e-62 XK27_08050 O stress-induced mitochondrial fusion
NAPPIDPI_01221 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
NAPPIDPI_01222 5.1e-96 GK ROK family
NAPPIDPI_01223 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NAPPIDPI_01224 1.3e-104 wecD M Acetyltransferase (GNAT) domain
NAPPIDPI_01225 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NAPPIDPI_01226 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NAPPIDPI_01227 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
NAPPIDPI_01229 7.7e-56 lrgA S Effector of murein hydrolase LrgA
NAPPIDPI_01230 2.2e-117 lrgB M effector of murein hydrolase
NAPPIDPI_01231 2.6e-109 3.1.3.18 S IA, variant 1
NAPPIDPI_01232 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NAPPIDPI_01233 7.4e-303 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NAPPIDPI_01234 8.2e-114 serB 3.1.3.3 E phosphoserine phosphatase
NAPPIDPI_01235 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NAPPIDPI_01236 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAPPIDPI_01237 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAPPIDPI_01238 9.6e-79 csn2 S CRISPR-associated protein (Cas_Csn2)
NAPPIDPI_01240 1.5e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
NAPPIDPI_01242 6.6e-30 ycaO O OsmC-like protein
NAPPIDPI_01243 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
NAPPIDPI_01246 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NAPPIDPI_01248 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NAPPIDPI_01249 1.1e-16 XK27_00735
NAPPIDPI_01251 5.2e-38 L Transposase
NAPPIDPI_01252 8.3e-18 L transposase activity
NAPPIDPI_01253 1.7e-12
NAPPIDPI_01256 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
NAPPIDPI_01257 6.4e-108 S Domain of unknown function (DUF1803)
NAPPIDPI_01258 7.8e-102 ygaC J Belongs to the UPF0374 family
NAPPIDPI_01259 2.8e-132 recX 2.4.1.337 GT4 S Regulatory protein RecX
NAPPIDPI_01260 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NAPPIDPI_01261 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
NAPPIDPI_01262 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
NAPPIDPI_01263 1.9e-115 S Haloacid dehalogenase-like hydrolase
NAPPIDPI_01264 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
NAPPIDPI_01265 5.8e-71 marR K Transcriptional regulator, MarR family
NAPPIDPI_01266 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NAPPIDPI_01267 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NAPPIDPI_01268 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
NAPPIDPI_01269 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NAPPIDPI_01270 1.6e-126 IQ reductase
NAPPIDPI_01271 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NAPPIDPI_01272 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NAPPIDPI_01273 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NAPPIDPI_01274 4.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NAPPIDPI_01275 4.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NAPPIDPI_01276 1.7e-137 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NAPPIDPI_01277 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NAPPIDPI_01278 5.2e-65 tnp L Transposase
NAPPIDPI_01279 8.1e-203 rny D Endoribonuclease that initiates mRNA decay
NAPPIDPI_01280 1.8e-84 L Transposase
NAPPIDPI_01281 5.6e-114 fruR K transcriptional
NAPPIDPI_01282 5.5e-164 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NAPPIDPI_01283 3.9e-54 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
NAPPIDPI_01284 2.2e-49 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
NAPPIDPI_01285 2.7e-126 fruA 2.7.1.202 G phosphotransferase system
NAPPIDPI_01286 1.2e-34 fruA 2.7.1.202 G phosphotransferase system
NAPPIDPI_01287 2.1e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NAPPIDPI_01288 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NAPPIDPI_01290 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NAPPIDPI_01291 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NAPPIDPI_01292 3.2e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NAPPIDPI_01293 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NAPPIDPI_01294 6.4e-29 2.3.1.128 K acetyltransferase
NAPPIDPI_01295 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NAPPIDPI_01296 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NAPPIDPI_01297 2e-126 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NAPPIDPI_01298 2.6e-64 WQ51_03320 S cog cog4835
NAPPIDPI_01299 5.8e-144 XK27_08360 S EDD domain protein, DegV family
NAPPIDPI_01300 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NAPPIDPI_01301 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NAPPIDPI_01302 0.0 yfmR S abc transporter atp-binding protein
NAPPIDPI_01303 1.6e-24 U response to pH
NAPPIDPI_01304 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
NAPPIDPI_01305 3.8e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
NAPPIDPI_01306 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NAPPIDPI_01307 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NAPPIDPI_01308 1.9e-77 K DNA-binding transcription factor activity
NAPPIDPI_01309 0.0 lmrA1 V abc transporter atp-binding protein
NAPPIDPI_01310 0.0 lmrA2 V abc transporter atp-binding protein
NAPPIDPI_01311 5.4e-45 K Acetyltransferase (GNAT) family
NAPPIDPI_01312 3.2e-78 sptS 2.7.13.3 T Histidine kinase
NAPPIDPI_01313 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NAPPIDPI_01314 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NAPPIDPI_01315 5.3e-161 cvfB S Protein conserved in bacteria
NAPPIDPI_01316 7.4e-35 yozE S Belongs to the UPF0346 family
NAPPIDPI_01317 4.5e-131 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
NAPPIDPI_01318 2.3e-61 rlpA M LysM domain protein
NAPPIDPI_01319 8e-191 phoH T phosphate starvation-inducible protein PhoH
NAPPIDPI_01323 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NAPPIDPI_01324 9.2e-164 K transcriptional regulator (lysR family)
NAPPIDPI_01325 1.4e-186 coiA 3.6.4.12 S Competence protein
NAPPIDPI_01326 0.0 pepF E oligoendopeptidase F
NAPPIDPI_01327 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
NAPPIDPI_01328 4.6e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
NAPPIDPI_01329 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NAPPIDPI_01330 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NAPPIDPI_01331 1.5e-152 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NAPPIDPI_01332 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
NAPPIDPI_01333 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
NAPPIDPI_01334 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NAPPIDPI_01335 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NAPPIDPI_01336 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NAPPIDPI_01337 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NAPPIDPI_01338 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NAPPIDPI_01339 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NAPPIDPI_01340 4.1e-132 yxkH G deacetylase
NAPPIDPI_01341 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NAPPIDPI_01342 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NAPPIDPI_01343 5.5e-153 rarD S Transporter
NAPPIDPI_01344 2.6e-16 T peptidase
NAPPIDPI_01345 8.9e-14 coiA 3.6.4.12 S Competence protein
NAPPIDPI_01346 5.7e-106 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NAPPIDPI_01347 5.3e-74 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NAPPIDPI_01348 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NAPPIDPI_01349 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NAPPIDPI_01350 3.1e-122 atpB C it plays a direct role in the translocation of protons across the membrane
NAPPIDPI_01351 3.3e-78 atpF C ATP synthase F(0) sector subunit b
NAPPIDPI_01352 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NAPPIDPI_01353 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NAPPIDPI_01354 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NAPPIDPI_01355 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NAPPIDPI_01356 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NAPPIDPI_01357 2.8e-230 ftsW D Belongs to the SEDS family
NAPPIDPI_01358 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NAPPIDPI_01359 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NAPPIDPI_01360 1.1e-110 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NAPPIDPI_01361 6.4e-162 holB 2.7.7.7 L dna polymerase iii
NAPPIDPI_01362 1.2e-135 yaaT S stage 0 sporulation protein
NAPPIDPI_01363 9.5e-55 yabA L Involved in initiation control of chromosome replication
NAPPIDPI_01364 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NAPPIDPI_01365 5.2e-226 amt P Ammonium Transporter
NAPPIDPI_01366 1.1e-53 glnB K Belongs to the P(II) protein family
NAPPIDPI_01367 4.9e-106 mur1 NU mannosyl-glycoprotein
NAPPIDPI_01368 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
NAPPIDPI_01369 3.8e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
NAPPIDPI_01370 3.6e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NAPPIDPI_01371 1.8e-53
NAPPIDPI_01372 7.5e-26
NAPPIDPI_01373 1.5e-59
NAPPIDPI_01374 6.1e-63 S membrane
NAPPIDPI_01375 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NAPPIDPI_01376 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NAPPIDPI_01377 4.5e-39 ynzC S UPF0291 protein
NAPPIDPI_01378 5.1e-246 cycA E permease
NAPPIDPI_01380 1.6e-24 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NAPPIDPI_01381 1.4e-47 pts33BCA G pts system
NAPPIDPI_01382 4.2e-119 pts33BCA G pts system
NAPPIDPI_01383 3.3e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
NAPPIDPI_01384 1.6e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NAPPIDPI_01389 1.8e-167 fhuR K transcriptional regulator (lysR family)
NAPPIDPI_01390 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NAPPIDPI_01391 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NAPPIDPI_01392 4e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NAPPIDPI_01393 4.9e-227 pyrP F uracil Permease
NAPPIDPI_01394 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NAPPIDPI_01395 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
NAPPIDPI_01396 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
NAPPIDPI_01397 1.2e-132 2.1.1.223 S Putative SAM-dependent methyltransferase
NAPPIDPI_01398 6.9e-18 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NAPPIDPI_01399 3.8e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NAPPIDPI_01400 4.1e-23 L COG2826 Transposase and inactivated derivatives, IS30 family
NAPPIDPI_01401 1.2e-08 S Antitoxin component of a toxin-antitoxin (TA) module
NAPPIDPI_01406 5.8e-95 V VanZ like family
NAPPIDPI_01407 6.8e-88 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NAPPIDPI_01408 1.1e-87 G Belongs to the phosphoglycerate mutase family
NAPPIDPI_01409 1.3e-199 S hmm pf01594
NAPPIDPI_01410 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NAPPIDPI_01411 8.3e-117 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NAPPIDPI_01412 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NAPPIDPI_01413 4.9e-39 S granule-associated protein
NAPPIDPI_01414 8.2e-293 S unusual protein kinase
NAPPIDPI_01415 3.4e-29 estA E Lysophospholipase L1 and related esterases
NAPPIDPI_01416 1.8e-69 estA E GDSL-like protein
NAPPIDPI_01417 1.2e-157 rssA S Phospholipase, patatin family
NAPPIDPI_01418 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
NAPPIDPI_01419 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
NAPPIDPI_01420 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
NAPPIDPI_01421 5.9e-22 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NAPPIDPI_01422 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NAPPIDPI_01423 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NAPPIDPI_01424 2.4e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NAPPIDPI_01425 0.0 S the current gene model (or a revised gene model) may contain a frame shift
NAPPIDPI_01426 3.5e-241 cas3 L CRISPR-associated helicase, Cas3
NAPPIDPI_01427 3.6e-46 hpk9 2.7.13.3 T protein histidine kinase activity
NAPPIDPI_01428 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NAPPIDPI_01429 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NAPPIDPI_01430 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NAPPIDPI_01431 0.0 lpdA 1.8.1.4 C Dehydrogenase
NAPPIDPI_01432 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NAPPIDPI_01433 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NAPPIDPI_01434 1.9e-186 3.5.1.28 M GBS Bsp-like repeat
NAPPIDPI_01435 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAPPIDPI_01436 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAPPIDPI_01437 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAPPIDPI_01438 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAPPIDPI_01439 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NAPPIDPI_01440 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NAPPIDPI_01441 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
NAPPIDPI_01442 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
NAPPIDPI_01443 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
NAPPIDPI_01444 5.6e-233 ycdB P peroxidase
NAPPIDPI_01445 1.1e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
NAPPIDPI_01446 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NAPPIDPI_01447 4.6e-25 tatA U protein secretion
NAPPIDPI_01448 2.3e-23 L Transposase
NAPPIDPI_01449 1.3e-48 malR K Transcriptional regulator
NAPPIDPI_01450 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NAPPIDPI_01451 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NAPPIDPI_01452 3.7e-09
NAPPIDPI_01453 1.1e-17
NAPPIDPI_01454 8.5e-187 lplA 6.3.1.20 H Lipoate-protein ligase
NAPPIDPI_01455 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NAPPIDPI_01456 0.0 pepN 3.4.11.2 E aminopeptidase
NAPPIDPI_01457 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
NAPPIDPI_01458 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NAPPIDPI_01459 1.4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NAPPIDPI_01460 1.2e-155 pstA P phosphate transport system permease
NAPPIDPI_01461 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
NAPPIDPI_01462 3.3e-158 pstS P phosphate
NAPPIDPI_01463 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NAPPIDPI_01464 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NAPPIDPI_01465 1.9e-43 yktA S Belongs to the UPF0223 family
NAPPIDPI_01466 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NAPPIDPI_01467 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NAPPIDPI_01468 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NAPPIDPI_01469 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
NAPPIDPI_01470 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
NAPPIDPI_01471 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
NAPPIDPI_01472 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NAPPIDPI_01473 9.3e-62 S haloacid dehalogenase-like hydrolase
NAPPIDPI_01474 1.8e-59 Q phosphatase activity
NAPPIDPI_01475 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
NAPPIDPI_01476 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NAPPIDPI_01477 1.8e-240 agcS E (Alanine) symporter
NAPPIDPI_01478 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NAPPIDPI_01479 1.4e-104 yfiF3 K sequence-specific DNA binding
NAPPIDPI_01480 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
NAPPIDPI_01481 4.4e-272 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NAPPIDPI_01483 2.3e-20 yecS P amino acid transport
NAPPIDPI_01484 1.6e-266 dtpT E transporter
NAPPIDPI_01486 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NAPPIDPI_01487 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NAPPIDPI_01488 5.2e-74 csm6 S Psort location Cytoplasmic, score
NAPPIDPI_01489 2.1e-14 csm6 S Psort location Cytoplasmic, score
NAPPIDPI_01490 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
NAPPIDPI_01491 2.9e-165 csm4 L CRISPR-associated RAMP protein, Csm4 family
NAPPIDPI_01492 1.1e-116 csm3 L RAMP superfamily
NAPPIDPI_01493 5.6e-62 csm2 L Pfam:DUF310
NAPPIDPI_01494 0.0 csm1 S CRISPR-associated protein Csm1 family
NAPPIDPI_01495 6.8e-133 cas6 S Pfam:DUF2276
NAPPIDPI_01496 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAPPIDPI_01497 1.2e-180 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAPPIDPI_01498 9.3e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NAPPIDPI_01499 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NAPPIDPI_01500 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
NAPPIDPI_01501 4.3e-118 S TraX protein
NAPPIDPI_01503 3.5e-28 3.4.13.21 I Protein conserved in bacteria
NAPPIDPI_01504 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
NAPPIDPI_01505 3.7e-190
NAPPIDPI_01506 2.3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NAPPIDPI_01508 3.9e-15 dinF V Mate efflux family protein
NAPPIDPI_01509 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
NAPPIDPI_01510 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
NAPPIDPI_01511 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
NAPPIDPI_01512 2.6e-143 2.4.2.3 F Phosphorylase superfamily
NAPPIDPI_01515 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
NAPPIDPI_01516 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
NAPPIDPI_01517 6e-08 S Hydrolases of the alpha beta superfamily
NAPPIDPI_01518 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NAPPIDPI_01519 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NAPPIDPI_01520 1.8e-159 czcD P cation diffusion facilitator family transporter
NAPPIDPI_01521 9e-98 K Transcriptional regulator, TetR family
NAPPIDPI_01522 1.6e-10
NAPPIDPI_01523 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NAPPIDPI_01524 6.4e-104 V ABC transporter (Permease
NAPPIDPI_01525 2.5e-23 L Transposase
NAPPIDPI_01526 1e-08 L transposition
NAPPIDPI_01527 1.1e-12
NAPPIDPI_01528 1.3e-87 S Fusaric acid resistance protein-like
NAPPIDPI_01529 8.5e-63 glnR K Transcriptional regulator
NAPPIDPI_01530 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
NAPPIDPI_01531 2.7e-40 pscB M CHAP domain protein
NAPPIDPI_01532 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NAPPIDPI_01533 2.5e-33 ykzG S Belongs to the UPF0356 family
NAPPIDPI_01534 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
NAPPIDPI_01535 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NAPPIDPI_01536 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NAPPIDPI_01537 3.8e-117 azlC E AzlC protein
NAPPIDPI_01538 8.8e-48 azlD E branched-chain amino acid
NAPPIDPI_01539 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NAPPIDPI_01540 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NAPPIDPI_01541 1.8e-159 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NAPPIDPI_01542 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NAPPIDPI_01543 1e-93 cvpA S toxin biosynthetic process
NAPPIDPI_01544 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NAPPIDPI_01545 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NAPPIDPI_01550 2.5e-230 mutY L A G-specific adenine glycosylase
NAPPIDPI_01551 3.6e-41 XK27_05745
NAPPIDPI_01552 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
NAPPIDPI_01553 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NAPPIDPI_01554 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NAPPIDPI_01556 2.6e-123 XK27_01040 S Pfam PF06570
NAPPIDPI_01557 2e-169 corA P COG0598 Mg2 and Co2 transporters
NAPPIDPI_01558 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NAPPIDPI_01561 2.4e-60 V 'abc transporter, ATP-binding protein
NAPPIDPI_01562 1.6e-19 V 'abc transporter, ATP-binding protein
NAPPIDPI_01563 1.3e-08 V 'abc transporter, ATP-binding protein
NAPPIDPI_01565 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
NAPPIDPI_01566 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
NAPPIDPI_01567 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NAPPIDPI_01568 3.4e-62 yqhY S protein conserved in bacteria
NAPPIDPI_01569 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NAPPIDPI_01570 2.2e-179 scrR K Transcriptional
NAPPIDPI_01571 5.4e-291 scrB 3.2.1.26 GH32 G invertase
NAPPIDPI_01572 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
NAPPIDPI_01573 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
NAPPIDPI_01574 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NAPPIDPI_01576 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NAPPIDPI_01577 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NAPPIDPI_01578 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NAPPIDPI_01579 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NAPPIDPI_01580 1.7e-183 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NAPPIDPI_01581 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NAPPIDPI_01583 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NAPPIDPI_01584 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
NAPPIDPI_01585 2.9e-18 yebC M Membrane
NAPPIDPI_01586 1.5e-80 yebC M Membrane
NAPPIDPI_01587 3.6e-66 KT response to antibiotic
NAPPIDPI_01588 5.2e-75 XK27_02470 K LytTr DNA-binding domain
NAPPIDPI_01589 2.6e-121 liaI S membrane
NAPPIDPI_01590 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NAPPIDPI_01591 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NAPPIDPI_01592 5.2e-125 S Protein of unknown function (DUF554)
NAPPIDPI_01593 8.1e-134 ecsA_2 V abc transporter atp-binding protein
NAPPIDPI_01594 1.4e-284 XK27_00765
NAPPIDPI_01595 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NAPPIDPI_01596 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NAPPIDPI_01597 4.5e-18 D nuclear chromosome segregation
NAPPIDPI_01598 8.7e-33 yhaI J Protein of unknown function (DUF805)
NAPPIDPI_01600 7.5e-30
NAPPIDPI_01601 7.4e-27
NAPPIDPI_01602 1.6e-65
NAPPIDPI_01603 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NAPPIDPI_01604 4.3e-47 ftsL D cell division protein FtsL
NAPPIDPI_01605 0.0 ftsI 3.4.16.4 M penicillin-binding protein
NAPPIDPI_01606 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NAPPIDPI_01607 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NAPPIDPI_01609 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NAPPIDPI_01610 2.3e-72 yutD J protein conserved in bacteria
NAPPIDPI_01611 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NAPPIDPI_01612 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
NAPPIDPI_01614 5.4e-81 mdlA V abc transporter atp-binding protein
NAPPIDPI_01615 4.5e-233 mdlA V abc transporter atp-binding protein
NAPPIDPI_01616 0.0 mdlB V abc transporter atp-binding protein
NAPPIDPI_01617 2.4e-139 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NAPPIDPI_01618 6.3e-252 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NAPPIDPI_01619 1.6e-236 mesE M Transport protein ComB
NAPPIDPI_01621 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
NAPPIDPI_01622 4e-133 agrA KT phosphorelay signal transduction system
NAPPIDPI_01625 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
NAPPIDPI_01634 4.7e-43
NAPPIDPI_01635 6.8e-56 S TM2 domain
NAPPIDPI_01636 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NAPPIDPI_01637 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NAPPIDPI_01638 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
NAPPIDPI_01639 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
NAPPIDPI_01640 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
NAPPIDPI_01641 6e-55 cof Q phosphatase activity
NAPPIDPI_01642 1.1e-34 cof Q phosphatase activity
NAPPIDPI_01643 3.1e-136 glcR K transcriptional regulator (DeoR family)
NAPPIDPI_01644 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NAPPIDPI_01645 3.8e-40 K transcriptional
NAPPIDPI_01647 2.6e-76 S thiolester hydrolase activity
NAPPIDPI_01648 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
NAPPIDPI_01649 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NAPPIDPI_01650 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NAPPIDPI_01651 1.9e-77 yhaI L Membrane
NAPPIDPI_01652 4.6e-260 pepC 3.4.22.40 E aminopeptidase
NAPPIDPI_01653 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NAPPIDPI_01654 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NAPPIDPI_01655 3.1e-95 ypsA S Belongs to the UPF0398 family
NAPPIDPI_01656 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NAPPIDPI_01657 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NAPPIDPI_01658 1.4e-172 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NAPPIDPI_01659 1.3e-106 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NAPPIDPI_01660 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
NAPPIDPI_01661 2.5e-23
NAPPIDPI_01662 7.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NAPPIDPI_01663 7.3e-80 XK27_09675 K -acetyltransferase
NAPPIDPI_01664 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NAPPIDPI_01665 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NAPPIDPI_01666 5.2e-59 L Integrase core domain protein
NAPPIDPI_01667 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NAPPIDPI_01668 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NAPPIDPI_01669 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NAPPIDPI_01670 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
NAPPIDPI_01671 2.6e-97 ybhL S Belongs to the BI1 family
NAPPIDPI_01674 1.6e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NAPPIDPI_01675 3.7e-91 K transcriptional regulator
NAPPIDPI_01676 7.6e-36 yneF S UPF0154 protein
NAPPIDPI_01677 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NAPPIDPI_01678 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NAPPIDPI_01679 3.5e-99 XK27_09740 S Phosphoesterase
NAPPIDPI_01680 7.8e-85 ykuL S CBS domain
NAPPIDPI_01681 1.1e-136 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NAPPIDPI_01682 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NAPPIDPI_01683 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NAPPIDPI_01684 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NAPPIDPI_01685 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NAPPIDPI_01686 1.2e-258 trkH P Cation transport protein
NAPPIDPI_01687 1.5e-247 trkA P Potassium transporter peripheral membrane component
NAPPIDPI_01688 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NAPPIDPI_01689 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NAPPIDPI_01690 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
NAPPIDPI_01691 9.5e-161 K sequence-specific DNA binding
NAPPIDPI_01692 1.2e-32 V protein secretion by the type I secretion system
NAPPIDPI_01693 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NAPPIDPI_01694 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NAPPIDPI_01695 1.6e-25 V protein secretion by the type I secretion system
NAPPIDPI_01696 1.8e-27 comA V protein secretion by the type I secretion system
NAPPIDPI_01697 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NAPPIDPI_01698 3.7e-51 yhaI L Membrane
NAPPIDPI_01699 6.7e-36 S Domain of unknown function (DUF4173)
NAPPIDPI_01700 9.2e-132 S Domain of unknown function (DUF4173)
NAPPIDPI_01701 6.8e-95 ureI S AmiS/UreI family transporter
NAPPIDPI_01702 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NAPPIDPI_01703 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NAPPIDPI_01704 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NAPPIDPI_01705 2.5e-77 ureE O enzyme active site formation
NAPPIDPI_01706 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NAPPIDPI_01707 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NAPPIDPI_01708 4.9e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NAPPIDPI_01709 2.7e-177 cbiM P PDGLE domain
NAPPIDPI_01710 1.1e-136 P cobalt transport protein
NAPPIDPI_01711 1.6e-131 cbiO P ABC transporter
NAPPIDPI_01712 4.5e-152 ET amino acid transport
NAPPIDPI_01713 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NAPPIDPI_01714 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
NAPPIDPI_01715 3.8e-205 EGP Transmembrane secretion effector
NAPPIDPI_01716 4e-153 ET amino acid transport
NAPPIDPI_01717 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
NAPPIDPI_01718 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NAPPIDPI_01719 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
NAPPIDPI_01720 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
NAPPIDPI_01721 5.8e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NAPPIDPI_01722 5.2e-98 metI P ABC transporter (Permease
NAPPIDPI_01723 5.1e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NAPPIDPI_01724 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
NAPPIDPI_01725 8e-94 S UPF0397 protein
NAPPIDPI_01726 0.0 ykoD P abc transporter atp-binding protein
NAPPIDPI_01727 1.2e-149 cbiQ P cobalt transport
NAPPIDPI_01728 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NAPPIDPI_01729 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
NAPPIDPI_01730 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NAPPIDPI_01731 3.4e-242 P COG0168 Trk-type K transport systems, membrane components
NAPPIDPI_01732 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
NAPPIDPI_01733 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
NAPPIDPI_01734 8.7e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NAPPIDPI_01735 2.8e-282 T PhoQ Sensor
NAPPIDPI_01736 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NAPPIDPI_01737 6.5e-218 dnaB L Replication initiation and membrane attachment
NAPPIDPI_01738 5.2e-167 dnaI L Primosomal protein DnaI
NAPPIDPI_01739 1.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NAPPIDPI_01740 1.2e-34
NAPPIDPI_01741 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
NAPPIDPI_01742 3e-27 L Integrase core domain protein
NAPPIDPI_01743 1.9e-46 L transposase activity
NAPPIDPI_01744 4e-50 L Transposase
NAPPIDPI_01745 8.7e-84 L Transposase
NAPPIDPI_01746 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NAPPIDPI_01747 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NAPPIDPI_01748 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NAPPIDPI_01749 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
NAPPIDPI_01751 3.5e-61 divIC D Septum formation initiator
NAPPIDPI_01752 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NAPPIDPI_01753 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NAPPIDPI_01754 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NAPPIDPI_01755 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NAPPIDPI_01756 1.1e-29 yyzM S Protein conserved in bacteria
NAPPIDPI_01757 7.7e-200 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NAPPIDPI_01758 5.3e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NAPPIDPI_01759 1e-134 parB K Belongs to the ParB family
NAPPIDPI_01760 5.3e-194 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NAPPIDPI_01761 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NAPPIDPI_01762 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
NAPPIDPI_01766 0.0 XK27_10405 S Bacterial membrane protein YfhO
NAPPIDPI_01767 6.7e-306 ybiT S abc transporter atp-binding protein
NAPPIDPI_01768 5.4e-153 yvjA S membrane
NAPPIDPI_01769 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NAPPIDPI_01770 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NAPPIDPI_01771 1.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NAPPIDPI_01772 2.3e-44 yaaA S S4 domain protein YaaA
NAPPIDPI_01773 4.8e-235 ymfF S Peptidase M16
NAPPIDPI_01774 7.1e-228 ymfH S Peptidase M16
NAPPIDPI_01775 6.3e-138 ymfM S sequence-specific DNA binding
NAPPIDPI_01776 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NAPPIDPI_01777 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NAPPIDPI_01778 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NAPPIDPI_01779 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NAPPIDPI_01780 5.3e-85 lytE M LysM domain protein
NAPPIDPI_01781 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
NAPPIDPI_01782 0.0 S Bacterial membrane protein, YfhO
NAPPIDPI_01783 6.7e-11 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NAPPIDPI_01784 1.3e-198 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NAPPIDPI_01785 1.5e-77 F NUDIX domain
NAPPIDPI_01786 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NAPPIDPI_01787 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NAPPIDPI_01788 3.9e-70 rplI J binds to the 23S rRNA
NAPPIDPI_01789 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NAPPIDPI_01790 8.2e-48 veg S Biofilm formation stimulator VEG
NAPPIDPI_01791 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NAPPIDPI_01792 2.7e-08
NAPPIDPI_01793 4.8e-55 ypaA M Membrane
NAPPIDPI_01794 1.9e-95 XK27_06935 K transcriptional regulator
NAPPIDPI_01795 3.9e-161 XK27_06930 V domain protein
NAPPIDPI_01796 1.8e-88 S Putative adhesin
NAPPIDPI_01797 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
NAPPIDPI_01799 1.7e-23 K negative regulation of transcription, DNA-templated
NAPPIDPI_01800 4e-19 K negative regulation of transcription, DNA-templated
NAPPIDPI_01801 3.4e-13 nudL L hydrolase
NAPPIDPI_01802 3.5e-97 nudL L hydrolase
NAPPIDPI_01803 4.9e-12 K CsbD-like
NAPPIDPI_01804 1.1e-71 M Protein conserved in bacteria
NAPPIDPI_01805 1.8e-23 S Small integral membrane protein
NAPPIDPI_01806 3.1e-101
NAPPIDPI_01807 3.7e-27 S Membrane
NAPPIDPI_01809 2.7e-95 S Hydrophobic domain protein
NAPPIDPI_01810 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
NAPPIDPI_01812 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NAPPIDPI_01813 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NAPPIDPI_01814 9.2e-36 metE 2.1.1.14 E Methionine synthase
NAPPIDPI_01815 7.6e-64 metE 2.1.1.14 E Methionine synthase
NAPPIDPI_01816 5.7e-52 metE 2.1.1.14 E Methionine synthase
NAPPIDPI_01817 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
NAPPIDPI_01819 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NAPPIDPI_01820 9.9e-169 XK27_01785 S cog cog1284
NAPPIDPI_01821 1.8e-147 yaaA S Belongs to the UPF0246 family
NAPPIDPI_01822 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NAPPIDPI_01823 2.6e-91 XK27_10930 K acetyltransferase
NAPPIDPI_01824 7.5e-14
NAPPIDPI_01825 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NAPPIDPI_01826 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
NAPPIDPI_01827 4.2e-44 yrzB S Belongs to the UPF0473 family
NAPPIDPI_01828 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NAPPIDPI_01829 2.8e-44 yrzL S Belongs to the UPF0297 family
NAPPIDPI_01830 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NAPPIDPI_01831 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NAPPIDPI_01833 3.5e-216 int L Belongs to the 'phage' integrase family
NAPPIDPI_01834 1.9e-18 S Domain of unknown function (DUF3173)
NAPPIDPI_01835 1.4e-107 L Replication initiation factor
NAPPIDPI_01836 1e-36 L Replication initiation factor
NAPPIDPI_01837 2.5e-89 K sequence-specific DNA binding
NAPPIDPI_01838 3.9e-287 V ABC transporter transmembrane region
NAPPIDPI_01839 3.4e-191 C Radical SAM
NAPPIDPI_01840 6.3e-16 C Radical SAM
NAPPIDPI_01842 7e-127 Z012_04635 K sequence-specific DNA binding
NAPPIDPI_01843 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NAPPIDPI_01844 2.1e-280 V ABC transporter
NAPPIDPI_01845 0.0 KLT serine threonine protein kinase
NAPPIDPI_01846 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NAPPIDPI_01849 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
NAPPIDPI_01850 2.7e-26 Q the current gene model (or a revised gene model) may contain a frame shift
NAPPIDPI_01851 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
NAPPIDPI_01853 3.2e-17 S Domain of unknown function (DUF4649)
NAPPIDPI_01854 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
NAPPIDPI_01855 2e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
NAPPIDPI_01856 4.4e-135 XK27_08845 S abc transporter atp-binding protein
NAPPIDPI_01857 1.1e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NAPPIDPI_01858 2e-151 estA CE1 S Putative esterase
NAPPIDPI_01859 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
NAPPIDPI_01860 5.5e-14 XK27_08880
NAPPIDPI_01861 1e-75 fld C Flavodoxin
NAPPIDPI_01862 9.8e-283 clcA P Chloride transporter, ClC family
NAPPIDPI_01863 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
NAPPIDPI_01864 2.1e-219 XK27_05110 P chloride
NAPPIDPI_01865 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NAPPIDPI_01867 7.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
NAPPIDPI_01868 3e-162 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NAPPIDPI_01869 2.7e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NAPPIDPI_01870 7.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NAPPIDPI_01871 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NAPPIDPI_01872 2.7e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NAPPIDPI_01873 3.5e-26 G Domain of unknown function (DUF4832)
NAPPIDPI_01874 1.9e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NAPPIDPI_01876 9.4e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NAPPIDPI_01877 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
NAPPIDPI_01878 3.5e-123 endA F DNA RNA non-specific endonuclease
NAPPIDPI_01879 2.5e-110 tcyB_2 P ABC transporter (permease)
NAPPIDPI_01880 8e-115 gltJ P ABC transporter (Permease
NAPPIDPI_01881 9.2e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NAPPIDPI_01882 3.3e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
NAPPIDPI_01883 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NAPPIDPI_01884 1.4e-245 vicK 2.7.13.3 T Histidine kinase
NAPPIDPI_01885 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
NAPPIDPI_01886 5e-35 F Protein of unknown function (DUF454)
NAPPIDPI_01887 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
NAPPIDPI_01888 9.2e-147 yidA S hydrolases of the HAD superfamily
NAPPIDPI_01889 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
NAPPIDPI_01890 2.6e-67 ywiB S Domain of unknown function (DUF1934)
NAPPIDPI_01891 0.0 pacL 3.6.3.8 P cation transport ATPase
NAPPIDPI_01892 1.5e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NAPPIDPI_01893 1.3e-181 yjjH S Calcineurin-like phosphoesterase
NAPPIDPI_01894 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NAPPIDPI_01895 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NAPPIDPI_01896 2.5e-124 ftsE D cell division ATP-binding protein FtsE
NAPPIDPI_01897 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NAPPIDPI_01898 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
NAPPIDPI_01899 6.2e-176 yubA S permease
NAPPIDPI_01900 2.4e-223 G COG0457 FOG TPR repeat
NAPPIDPI_01901 1.8e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NAPPIDPI_01902 1.1e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NAPPIDPI_01903 2e-61 ebsA S Family of unknown function (DUF5322)
NAPPIDPI_01904 2.8e-18 M LysM domain
NAPPIDPI_01905 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NAPPIDPI_01906 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NAPPIDPI_01907 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NAPPIDPI_01908 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NAPPIDPI_01909 2.9e-84 L Transposase
NAPPIDPI_01910 6.9e-86 XK27_03610 K Gnat family
NAPPIDPI_01911 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NAPPIDPI_01912 2.4e-275 pepV 3.5.1.18 E Dipeptidase
NAPPIDPI_01913 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
NAPPIDPI_01914 6.1e-22 V Glucan-binding protein C
NAPPIDPI_01916 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NAPPIDPI_01917 7.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NAPPIDPI_01918 8.1e-41 S Protein of unknown function (DUF1697)
NAPPIDPI_01919 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NAPPIDPI_01920 4e-64 clcA_2 P chloride
NAPPIDPI_01921 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
NAPPIDPI_01922 7e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
NAPPIDPI_01923 1.9e-127 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
NAPPIDPI_01924 2.9e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
NAPPIDPI_01925 5.6e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
NAPPIDPI_01926 1.7e-109 cps4C M biosynthesis protein
NAPPIDPI_01927 2e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
NAPPIDPI_01928 2.7e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NAPPIDPI_01929 7.2e-217 rgpAc GT4 M group 1 family protein
NAPPIDPI_01930 2.3e-207 wcoF M Glycosyltransferase, group 1 family protein
NAPPIDPI_01931 2.2e-84 Z012_10770 M Domain of unknown function (DUF1919)
NAPPIDPI_01932 2.3e-168 M Glycosyltransferase, group 2 family protein
NAPPIDPI_01933 6.6e-96 sacB GT2,GT4 M transferase activity, transferring glycosyl groups
NAPPIDPI_01934 2.5e-176 cps1B GT2,GT4 M Glycosyl transferases group 1
NAPPIDPI_01935 2.6e-11 cps3F
NAPPIDPI_01936 1.4e-246 cps1C S Polysaccharide biosynthesis protein
NAPPIDPI_01937 2.7e-160 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NAPPIDPI_01938 3.8e-20 rmlC 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
NAPPIDPI_01939 1.4e-53 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)