ORF_ID e_value Gene_name EC_number CAZy COGs Description
FADFFPFK_00001 3.4e-39 S COG NOG14552 non supervised orthologous group
FADFFPFK_00002 1.3e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
FADFFPFK_00003 2.4e-92 M1-753 M FR47-like protein
FADFFPFK_00004 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
FADFFPFK_00005 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
FADFFPFK_00006 3.9e-84 yuaE S DinB superfamily
FADFFPFK_00007 7.4e-106 yuaD
FADFFPFK_00008 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
FADFFPFK_00009 5.2e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
FADFFPFK_00010 1.9e-92 yuaC K Belongs to the GbsR family
FADFFPFK_00011 2.2e-91 yuaB
FADFFPFK_00012 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
FADFFPFK_00013 1.8e-235 ktrB P Potassium
FADFFPFK_00014 1e-38 yiaA S yiaA/B two helix domain
FADFFPFK_00015 1.1e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FADFFPFK_00016 7.5e-275 yubD P Major Facilitator Superfamily
FADFFPFK_00017 2.2e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
FADFFPFK_00019 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
FADFFPFK_00020 5e-186 yubA S transporter activity
FADFFPFK_00021 3.7e-182 ygjR S Oxidoreductase
FADFFPFK_00022 1.1e-250 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
FADFFPFK_00023 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
FADFFPFK_00024 2.7e-274 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
FADFFPFK_00025 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
FADFFPFK_00026 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
FADFFPFK_00027 7.3e-238 mcpA NT chemotaxis protein
FADFFPFK_00028 5.5e-294 mcpA NT chemotaxis protein
FADFFPFK_00029 1.1e-220 mcpA NT chemotaxis protein
FADFFPFK_00030 1.3e-223 mcpA NT chemotaxis protein
FADFFPFK_00031 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
FADFFPFK_00032 1e-35
FADFFPFK_00033 3.1e-71 yugU S Uncharacterised protein family UPF0047
FADFFPFK_00034 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
FADFFPFK_00035 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
FADFFPFK_00036 1.4e-116 yugP S Zn-dependent protease
FADFFPFK_00037 2.3e-38
FADFFPFK_00038 1.1e-53 mstX S Membrane-integrating protein Mistic
FADFFPFK_00039 1.1e-181 yugO P COG1226 Kef-type K transport systems
FADFFPFK_00040 1.3e-72 yugN S YugN-like family
FADFFPFK_00042 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
FADFFPFK_00043 5.3e-228 yugK C Dehydrogenase
FADFFPFK_00044 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
FADFFPFK_00045 1.1e-34 yuzA S Domain of unknown function (DUF378)
FADFFPFK_00046 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
FADFFPFK_00047 2.1e-199 yugH 2.6.1.1 E Aminotransferase
FADFFPFK_00048 1.6e-85 alaR K Transcriptional regulator
FADFFPFK_00049 1.4e-155 yugF I Hydrolase
FADFFPFK_00050 2.7e-39 yugE S Domain of unknown function (DUF1871)
FADFFPFK_00051 1.1e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
FADFFPFK_00052 2.3e-232 T PhoQ Sensor
FADFFPFK_00053 6.3e-69 kapB G Kinase associated protein B
FADFFPFK_00054 4.2e-115 kapD L the KinA pathway to sporulation
FADFFPFK_00056 6.5e-185 yuxJ EGP Major facilitator Superfamily
FADFFPFK_00057 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
FADFFPFK_00058 6.3e-75 yuxK S protein conserved in bacteria
FADFFPFK_00059 6.3e-78 yufK S Family of unknown function (DUF5366)
FADFFPFK_00060 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
FADFFPFK_00061 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
FADFFPFK_00062 9.9e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
FADFFPFK_00063 7.8e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
FADFFPFK_00064 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
FADFFPFK_00065 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
FADFFPFK_00066 8.2e-233 maeN C COG3493 Na citrate symporter
FADFFPFK_00067 5e-15
FADFFPFK_00068 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
FADFFPFK_00069 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FADFFPFK_00070 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FADFFPFK_00071 2.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FADFFPFK_00072 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FADFFPFK_00073 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FADFFPFK_00074 2.8e-58 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
FADFFPFK_00075 6e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
FADFFPFK_00076 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FADFFPFK_00077 3.2e-269 comP 2.7.13.3 T Histidine kinase
FADFFPFK_00079 4.7e-142 comQ H Belongs to the FPP GGPP synthase family
FADFFPFK_00081 5e-23 yuzC
FADFFPFK_00082 1.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
FADFFPFK_00083 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FADFFPFK_00084 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
FADFFPFK_00085 7.9e-67 yueI S Protein of unknown function (DUF1694)
FADFFPFK_00086 7.4e-39 yueH S YueH-like protein
FADFFPFK_00087 6.6e-31 yueG S Spore germination protein gerPA/gerPF
FADFFPFK_00088 5.4e-190 yueF S transporter activity
FADFFPFK_00089 1e-17 S Protein of unknown function (DUF2283)
FADFFPFK_00090 2.9e-24 S Protein of unknown function (DUF2642)
FADFFPFK_00091 4.8e-96 yueE S phosphohydrolase
FADFFPFK_00092 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FADFFPFK_00093 3.3e-64 yueC S Family of unknown function (DUF5383)
FADFFPFK_00094 0.0 esaA S type VII secretion protein EsaA
FADFFPFK_00095 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
FADFFPFK_00096 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
FADFFPFK_00097 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
FADFFPFK_00098 2.8e-45 esxA S Belongs to the WXG100 family
FADFFPFK_00099 1.9e-228 yukF QT Transcriptional regulator
FADFFPFK_00100 5.2e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
FADFFPFK_00101 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
FADFFPFK_00102 8.5e-36 mbtH S MbtH-like protein
FADFFPFK_00103 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FADFFPFK_00104 4.9e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
FADFFPFK_00105 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
FADFFPFK_00106 5.6e-225 entC 5.4.4.2 HQ Isochorismate synthase
FADFFPFK_00107 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FADFFPFK_00108 5.6e-166 besA S Putative esterase
FADFFPFK_00109 1.9e-120 yuiH S Oxidoreductase molybdopterin binding domain
FADFFPFK_00110 9.7e-93 bioY S Biotin biosynthesis protein
FADFFPFK_00111 3.9e-211 yuiF S antiporter
FADFFPFK_00112 3.8e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FADFFPFK_00113 2e-77 yuiD S protein conserved in bacteria
FADFFPFK_00114 6.2e-117 yuiC S protein conserved in bacteria
FADFFPFK_00115 8.4e-27 yuiB S Putative membrane protein
FADFFPFK_00116 2.1e-235 yumB 1.6.99.3 C NADH dehydrogenase
FADFFPFK_00117 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
FADFFPFK_00119 1.1e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FADFFPFK_00120 6.5e-116 paiB K Putative FMN-binding domain
FADFFPFK_00121 1e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FADFFPFK_00122 3.7e-63 erpA S Belongs to the HesB IscA family
FADFFPFK_00123 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FADFFPFK_00124 4.5e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FADFFPFK_00125 3.2e-39 yuzB S Belongs to the UPF0349 family
FADFFPFK_00126 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
FADFFPFK_00127 1.1e-55 yuzD S protein conserved in bacteria
FADFFPFK_00128 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
FADFFPFK_00129 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
FADFFPFK_00130 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
FADFFPFK_00131 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FADFFPFK_00132 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
FADFFPFK_00133 2.9e-198 yutH S Spore coat protein
FADFFPFK_00134 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
FADFFPFK_00135 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
FADFFPFK_00136 8.6e-75 yutE S Protein of unknown function DUF86
FADFFPFK_00137 9.7e-48 yutD S protein conserved in bacteria
FADFFPFK_00138 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FADFFPFK_00139 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FADFFPFK_00140 1.3e-195 lytH M Peptidase, M23
FADFFPFK_00141 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
FADFFPFK_00142 3.1e-47 yunC S Domain of unknown function (DUF1805)
FADFFPFK_00143 5.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
FADFFPFK_00144 4.5e-141 yunE S membrane transporter protein
FADFFPFK_00145 4.3e-171 yunF S Protein of unknown function DUF72
FADFFPFK_00146 6.9e-59 yunG
FADFFPFK_00147 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
FADFFPFK_00148 2.4e-300 pucR QT COG2508 Regulator of polyketide synthase expression
FADFFPFK_00149 5.5e-229 pbuX F Permease family
FADFFPFK_00150 1.9e-223 pbuX F xanthine
FADFFPFK_00151 9.2e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
FADFFPFK_00152 3.2e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
FADFFPFK_00155 2.8e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
FADFFPFK_00156 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
FADFFPFK_00157 4e-145 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
FADFFPFK_00158 5.8e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
FADFFPFK_00159 3.4e-183 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FADFFPFK_00160 9.3e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
FADFFPFK_00161 1.7e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
FADFFPFK_00162 3.5e-168 bsn L Ribonuclease
FADFFPFK_00163 8.5e-204 msmX P Belongs to the ABC transporter superfamily
FADFFPFK_00164 1.4e-133 yurK K UTRA
FADFFPFK_00165 7.4e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
FADFFPFK_00166 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
FADFFPFK_00167 6.9e-156 yurN G Binding-protein-dependent transport system inner membrane component
FADFFPFK_00168 9.4e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
FADFFPFK_00169 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
FADFFPFK_00170 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
FADFFPFK_00171 2.3e-204 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
FADFFPFK_00173 1.4e-41
FADFFPFK_00174 7.1e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FADFFPFK_00175 3.5e-271 sufB O FeS cluster assembly
FADFFPFK_00176 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
FADFFPFK_00177 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FADFFPFK_00178 1.4e-245 sufD O assembly protein SufD
FADFFPFK_00179 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
FADFFPFK_00180 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FADFFPFK_00181 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
FADFFPFK_00182 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
FADFFPFK_00183 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FADFFPFK_00184 2.4e-56 yusD S SCP-2 sterol transfer family
FADFFPFK_00185 5.6e-55 traF CO Thioredoxin
FADFFPFK_00186 8.2e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
FADFFPFK_00187 4.1e-39 yusG S Protein of unknown function (DUF2553)
FADFFPFK_00188 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
FADFFPFK_00189 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
FADFFPFK_00190 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
FADFFPFK_00191 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
FADFFPFK_00192 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
FADFFPFK_00193 8.1e-09 S YuzL-like protein
FADFFPFK_00194 4.6e-163 fadM E Proline dehydrogenase
FADFFPFK_00195 5.1e-40
FADFFPFK_00196 5.4e-53 yusN M Coat F domain
FADFFPFK_00197 3e-73 yusO K Iron dependent repressor, N-terminal DNA binding domain
FADFFPFK_00198 8.5e-293 yusP P Major facilitator superfamily
FADFFPFK_00199 1.5e-62 yusQ S Tautomerase enzyme
FADFFPFK_00200 1.6e-105 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FADFFPFK_00201 5.7e-158 yusT K LysR substrate binding domain
FADFFPFK_00202 9.6e-39 yusU S Protein of unknown function (DUF2573)
FADFFPFK_00203 2.3e-153 yusV 3.6.3.34 HP ABC transporter
FADFFPFK_00204 7.4e-66 S YusW-like protein
FADFFPFK_00205 2.3e-299 pepF2 E COG1164 Oligoendopeptidase F
FADFFPFK_00206 3.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FADFFPFK_00207 2.7e-79 dps P Ferritin-like domain
FADFFPFK_00208 2e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FADFFPFK_00209 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_00210 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
FADFFPFK_00211 9.6e-158 yuxN K Transcriptional regulator
FADFFPFK_00212 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
FADFFPFK_00213 3.9e-24 S Protein of unknown function (DUF3970)
FADFFPFK_00214 7.2e-243 gerAA EG Spore germination protein
FADFFPFK_00215 6.1e-194 gerAB E Spore germination protein
FADFFPFK_00216 9.7e-179 gerAC S Spore germination B3/ GerAC like, C-terminal
FADFFPFK_00217 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FADFFPFK_00218 3.5e-186 vraS 2.7.13.3 T Histidine kinase
FADFFPFK_00219 6.1e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
FADFFPFK_00220 4.1e-124 liaG S Putative adhesin
FADFFPFK_00221 4e-103 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
FADFFPFK_00222 7.3e-62 liaI S membrane
FADFFPFK_00223 1.4e-226 yvqJ EGP Major facilitator Superfamily
FADFFPFK_00224 6.7e-99 yvqK 2.5.1.17 S Adenosyltransferase
FADFFPFK_00225 1.8e-240 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
FADFFPFK_00226 7.2e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_00227 1.5e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
FADFFPFK_00228 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FADFFPFK_00229 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
FADFFPFK_00230 0.0 T PhoQ Sensor
FADFFPFK_00231 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_00232 7.2e-23
FADFFPFK_00233 9.5e-98 yvrI K RNA polymerase
FADFFPFK_00234 2.4e-19 S YvrJ protein family
FADFFPFK_00235 2e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
FADFFPFK_00236 3.8e-64 yvrL S Regulatory protein YrvL
FADFFPFK_00237 1.5e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
FADFFPFK_00238 1.6e-123 macB V ABC transporter, ATP-binding protein
FADFFPFK_00239 2e-174 M Efflux transporter rnd family, mfp subunit
FADFFPFK_00240 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
FADFFPFK_00241 1.5e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_00242 7.4e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_00243 2.6e-177 fhuD P ABC transporter
FADFFPFK_00244 4.9e-236 yvsH E Arginine ornithine antiporter
FADFFPFK_00245 6.5e-16 S Small spore protein J (Spore_SspJ)
FADFFPFK_00246 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
FADFFPFK_00247 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FADFFPFK_00248 6.4e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
FADFFPFK_00249 3.9e-134 modA P COG0725 ABC-type molybdate transport system, periplasmic component
FADFFPFK_00250 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
FADFFPFK_00251 5.9e-157 yvgN S reductase
FADFFPFK_00252 2.1e-85 yvgO
FADFFPFK_00253 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
FADFFPFK_00254 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
FADFFPFK_00255 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FADFFPFK_00256 0.0 helD 3.6.4.12 L DNA helicase
FADFFPFK_00258 1.6e-106 yvgT S membrane
FADFFPFK_00259 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
FADFFPFK_00260 1.6e-104 bdbD O Thioredoxin
FADFFPFK_00261 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
FADFFPFK_00262 0.0 copA 3.6.3.54 P P-type ATPase
FADFFPFK_00263 1.5e-29 copZ P Copper resistance protein CopZ
FADFFPFK_00264 2.2e-48 csoR S transcriptional
FADFFPFK_00265 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
FADFFPFK_00266 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FADFFPFK_00267 0.0 yvaC S Fusaric acid resistance protein-like
FADFFPFK_00268 2.8e-72 yvaD S Family of unknown function (DUF5360)
FADFFPFK_00269 2e-53 yvaE P Small Multidrug Resistance protein
FADFFPFK_00270 4.3e-98 K Bacterial regulatory proteins, tetR family
FADFFPFK_00271 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FADFFPFK_00273 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FADFFPFK_00274 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FADFFPFK_00275 5.6e-143 est 3.1.1.1 S Carboxylesterase
FADFFPFK_00276 2.4e-23 secG U Preprotein translocase subunit SecG
FADFFPFK_00277 1.8e-152 yvaM S Serine aminopeptidase, S33
FADFFPFK_00278 7.5e-36 yvzC K Transcriptional
FADFFPFK_00279 4e-69 K transcriptional
FADFFPFK_00280 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
FADFFPFK_00281 1.4e-53 yodB K transcriptional
FADFFPFK_00283 6.2e-22 S Protein of unknown function (DUF2283)
FADFFPFK_00284 1.9e-15 M COG3209 Rhs family protein
FADFFPFK_00285 2e-42 aprE 3.4.21.62 O Belongs to the peptidase S8 family
FADFFPFK_00286 6.7e-100 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
FADFFPFK_00287 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
FADFFPFK_00288 4.7e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
FADFFPFK_00289 1.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
FADFFPFK_00290 1.9e-60 yvbF K Belongs to the GbsR family
FADFFPFK_00291 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
FADFFPFK_00292 1.8e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
FADFFPFK_00293 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
FADFFPFK_00294 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
FADFFPFK_00295 3.5e-97 yvbF K Belongs to the GbsR family
FADFFPFK_00296 2.3e-100 yvbG U UPF0056 membrane protein
FADFFPFK_00297 8.6e-113 yvbH S YvbH-like oligomerisation region
FADFFPFK_00298 4e-122 exoY M Membrane
FADFFPFK_00299 0.0 tcaA S response to antibiotic
FADFFPFK_00300 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
FADFFPFK_00301 1.6e-241 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FADFFPFK_00302 2.2e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
FADFFPFK_00303 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FADFFPFK_00304 8.5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
FADFFPFK_00305 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FADFFPFK_00306 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
FADFFPFK_00307 1.6e-252 araE EGP Major facilitator Superfamily
FADFFPFK_00308 5.5e-203 araR K transcriptional
FADFFPFK_00309 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FADFFPFK_00310 3.9e-159 yvbU K Transcriptional regulator
FADFFPFK_00311 9.4e-156 yvbV EG EamA-like transporter family
FADFFPFK_00312 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
FADFFPFK_00313 5.4e-192 yvbX S Glycosyl hydrolase
FADFFPFK_00314 4.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
FADFFPFK_00315 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
FADFFPFK_00316 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
FADFFPFK_00317 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FADFFPFK_00318 2.1e-197 desK 2.7.13.3 T Histidine kinase
FADFFPFK_00319 1.4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
FADFFPFK_00320 3.1e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
FADFFPFK_00321 2.6e-157 rsbQ S Alpha/beta hydrolase family
FADFFPFK_00322 2.9e-197 rsbU 3.1.3.3 T response regulator
FADFFPFK_00323 1.1e-250 galA 3.2.1.89 G arabinogalactan
FADFFPFK_00324 0.0 lacA 3.2.1.23 G beta-galactosidase
FADFFPFK_00325 7.2e-150 ganQ P transport
FADFFPFK_00326 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
FADFFPFK_00327 3.7e-227 cycB G COG2182 Maltose-binding periplasmic proteins domains
FADFFPFK_00328 1.8e-184 lacR K Transcriptional regulator
FADFFPFK_00329 1e-112 yvfI K COG2186 Transcriptional regulators
FADFFPFK_00330 2.6e-308 yvfH C L-lactate permease
FADFFPFK_00331 1.4e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
FADFFPFK_00332 1e-31 yvfG S YvfG protein
FADFFPFK_00333 1.7e-187 yvfF GM Exopolysaccharide biosynthesis protein
FADFFPFK_00334 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
FADFFPFK_00335 2.4e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
FADFFPFK_00336 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
FADFFPFK_00337 1.7e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FADFFPFK_00338 5.6e-189 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
FADFFPFK_00339 4e-206 epsI GM pyruvyl transferase
FADFFPFK_00340 2.2e-193 epsH GT2 S Glycosyltransferase like family 2
FADFFPFK_00341 1.1e-206 epsG S EpsG family
FADFFPFK_00342 1.4e-217 epsF GT4 M Glycosyl transferases group 1
FADFFPFK_00343 2.7e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FADFFPFK_00344 1.2e-219 epsD GT4 M Glycosyl transferase 4-like
FADFFPFK_00345 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
FADFFPFK_00346 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
FADFFPFK_00347 4e-122 ywqC M biosynthesis protein
FADFFPFK_00348 6.3e-76 slr K transcriptional
FADFFPFK_00349 2.9e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
FADFFPFK_00351 4.6e-93 padC Q Phenolic acid decarboxylase
FADFFPFK_00352 2.6e-47 MA20_18690 S Protein of unknown function (DUF3237)
FADFFPFK_00353 4.4e-126 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
FADFFPFK_00354 1.6e-260 pbpE V Beta-lactamase
FADFFPFK_00355 9.3e-66
FADFFPFK_00356 1.7e-273 sacB 2.4.1.10 GH68 M levansucrase activity
FADFFPFK_00357 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
FADFFPFK_00358 1.8e-295 yveA E amino acid
FADFFPFK_00359 7.4e-106 yvdT K Transcriptional regulator
FADFFPFK_00360 1.5e-50 ykkC P Small Multidrug Resistance protein
FADFFPFK_00361 7.1e-50 sugE P Small Multidrug Resistance protein
FADFFPFK_00362 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
FADFFPFK_00363 1.4e-173 S Patatin-like phospholipase
FADFFPFK_00365 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FADFFPFK_00366 2.3e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
FADFFPFK_00367 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
FADFFPFK_00368 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
FADFFPFK_00369 5e-154 malA S Protein of unknown function (DUF1189)
FADFFPFK_00370 1.1e-147 malD P transport
FADFFPFK_00371 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
FADFFPFK_00372 3.4e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
FADFFPFK_00373 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
FADFFPFK_00374 1.3e-171 yvdE K Transcriptional regulator
FADFFPFK_00375 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
FADFFPFK_00376 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
FADFFPFK_00377 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
FADFFPFK_00378 8.2e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
FADFFPFK_00379 1.1e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FADFFPFK_00380 0.0 yxdM V ABC transporter (permease)
FADFFPFK_00381 5.6e-141 yvcR V ABC transporter, ATP-binding protein
FADFFPFK_00382 3.4e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
FADFFPFK_00383 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_00384 9.7e-32
FADFFPFK_00385 2.1e-145 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
FADFFPFK_00386 1.6e-36 crh G Phosphocarrier protein Chr
FADFFPFK_00387 4.1e-170 whiA K May be required for sporulation
FADFFPFK_00388 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
FADFFPFK_00389 5.7e-166 rapZ S Displays ATPase and GTPase activities
FADFFPFK_00390 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
FADFFPFK_00391 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
FADFFPFK_00392 1.6e-98 usp CBM50 M protein conserved in bacteria
FADFFPFK_00393 2.2e-276 S COG0457 FOG TPR repeat
FADFFPFK_00394 0.0 msbA2 3.6.3.44 V ABC transporter
FADFFPFK_00396 0.0
FADFFPFK_00397 2.4e-77
FADFFPFK_00398 4.5e-109 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
FADFFPFK_00399 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FADFFPFK_00400 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FADFFPFK_00401 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FADFFPFK_00402 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
FADFFPFK_00403 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FADFFPFK_00404 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
FADFFPFK_00405 4.5e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FADFFPFK_00406 1e-139 yvpB NU protein conserved in bacteria
FADFFPFK_00407 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
FADFFPFK_00408 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
FADFFPFK_00409 1.9e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
FADFFPFK_00410 4.9e-160 yvoD P COG0370 Fe2 transport system protein B
FADFFPFK_00411 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FADFFPFK_00412 6.4e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FADFFPFK_00413 1.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
FADFFPFK_00414 2.3e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FADFFPFK_00415 1.2e-132 yvoA K transcriptional
FADFFPFK_00416 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
FADFFPFK_00417 1.2e-50 yvlD S Membrane
FADFFPFK_00418 2.6e-26 pspB KT PspC domain
FADFFPFK_00419 9.2e-166 yvlB S Putative adhesin
FADFFPFK_00420 8e-49 yvlA
FADFFPFK_00421 5.7e-33 yvkN
FADFFPFK_00422 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FADFFPFK_00423 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FADFFPFK_00424 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FADFFPFK_00425 1.2e-30 csbA S protein conserved in bacteria
FADFFPFK_00426 0.0 yvkC 2.7.9.2 GT Phosphotransferase
FADFFPFK_00427 1e-99 yvkB K Transcriptional regulator
FADFFPFK_00428 3.3e-226 yvkA EGP Major facilitator Superfamily
FADFFPFK_00429 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FADFFPFK_00430 5.3e-56 swrA S Swarming motility protein
FADFFPFK_00431 2.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
FADFFPFK_00432 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
FADFFPFK_00433 2.7e-123 ftsE D cell division ATP-binding protein FtsE
FADFFPFK_00434 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
FADFFPFK_00435 3.5e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
FADFFPFK_00436 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FADFFPFK_00437 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FADFFPFK_00438 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FADFFPFK_00439 4.6e-51
FADFFPFK_00440 1.9e-08 fliT S bacterial-type flagellum organization
FADFFPFK_00441 6.5e-69 fliS N flagellar protein FliS
FADFFPFK_00442 2e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FADFFPFK_00443 1.2e-55 flaG N flagellar protein FlaG
FADFFPFK_00444 1.4e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FADFFPFK_00445 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FADFFPFK_00446 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FADFFPFK_00447 1.3e-49 yviE
FADFFPFK_00448 7.8e-155 flgL N Belongs to the bacterial flagellin family
FADFFPFK_00449 1.2e-264 flgK N flagellar hook-associated protein
FADFFPFK_00450 3.9e-76 flgN NOU FlgN protein
FADFFPFK_00451 2.3e-38 flgM KNU Negative regulator of flagellin synthesis
FADFFPFK_00452 7e-74 yvyF S flagellar protein
FADFFPFK_00453 2.6e-80 comFC S Phosphoribosyl transferase domain
FADFFPFK_00454 3.7e-45 comFB S Late competence development protein ComFB
FADFFPFK_00455 3.8e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FADFFPFK_00456 2.1e-154 degV S protein conserved in bacteria
FADFFPFK_00457 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FADFFPFK_00458 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
FADFFPFK_00459 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
FADFFPFK_00460 5.9e-163 yvhJ K Transcriptional regulator
FADFFPFK_00461 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
FADFFPFK_00462 1.7e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
FADFFPFK_00463 6.2e-145 tuaG GT2 M Glycosyltransferase like family 2
FADFFPFK_00464 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
FADFFPFK_00465 1.8e-262 tuaE M Teichuronic acid biosynthesis protein
FADFFPFK_00466 9.9e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FADFFPFK_00467 4e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
FADFFPFK_00468 2.4e-246 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FADFFPFK_00469 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
FADFFPFK_00470 1.9e-94 M Glycosyltransferase like family 2
FADFFPFK_00471 1e-207 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FADFFPFK_00472 0.0 lytB 3.5.1.28 D Stage II sporulation protein
FADFFPFK_00473 1e-11
FADFFPFK_00474 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
FADFFPFK_00475 2.1e-213 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
FADFFPFK_00476 2.1e-88 M Glycosyltransferase like family 2
FADFFPFK_00477 2.7e-99 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
FADFFPFK_00478 3.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
FADFFPFK_00479 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FADFFPFK_00480 1.1e-273 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
FADFFPFK_00481 1e-132 tagG GM Transport permease protein
FADFFPFK_00482 2.7e-73
FADFFPFK_00484 2.7e-55
FADFFPFK_00485 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FADFFPFK_00486 2.9e-89 ggaA M Glycosyltransferase like family 2
FADFFPFK_00487 2.5e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FADFFPFK_00488 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
FADFFPFK_00489 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
FADFFPFK_00490 1.9e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FADFFPFK_00491 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
FADFFPFK_00492 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
FADFFPFK_00493 1.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FADFFPFK_00494 3.3e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FADFFPFK_00495 7.5e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FADFFPFK_00496 2.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
FADFFPFK_00497 5.7e-264 gerBA EG Spore germination protein
FADFFPFK_00498 8.1e-194 gerBB E Spore germination protein
FADFFPFK_00499 5.8e-208 gerAC S Spore germination protein
FADFFPFK_00500 7.8e-247 ywtG EGP Major facilitator Superfamily
FADFFPFK_00501 2.4e-170 ywtF K Transcriptional regulator
FADFFPFK_00502 9.1e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
FADFFPFK_00503 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
FADFFPFK_00504 3.6e-21 ywtC
FADFFPFK_00505 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
FADFFPFK_00506 8.6e-70 pgsC S biosynthesis protein
FADFFPFK_00507 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
FADFFPFK_00508 5.5e-178 rbsR K transcriptional
FADFFPFK_00509 1.6e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FADFFPFK_00510 1.1e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
FADFFPFK_00511 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
FADFFPFK_00512 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
FADFFPFK_00513 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
FADFFPFK_00514 7.3e-92 batE T Sh3 type 3 domain protein
FADFFPFK_00515 8e-48 ywsA S Protein of unknown function (DUF3892)
FADFFPFK_00516 2.8e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
FADFFPFK_00517 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
FADFFPFK_00518 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
FADFFPFK_00519 1.1e-169 alsR K LysR substrate binding domain
FADFFPFK_00520 1.8e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FADFFPFK_00521 1.1e-124 ywrJ
FADFFPFK_00522 2.8e-123 cotB
FADFFPFK_00523 6.2e-207 cotH M Spore Coat
FADFFPFK_00524 1.3e-12
FADFFPFK_00525 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FADFFPFK_00526 1.1e-53 S Domain of unknown function (DUF4181)
FADFFPFK_00527 3.1e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
FADFFPFK_00528 8e-82 ywrC K Transcriptional regulator
FADFFPFK_00529 7.1e-104 ywrB P Chromate transporter
FADFFPFK_00530 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
FADFFPFK_00532 2.4e-98 ywqN S NAD(P)H-dependent
FADFFPFK_00533 1.4e-161 K Transcriptional regulator
FADFFPFK_00534 6.7e-125 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
FADFFPFK_00535 8e-80
FADFFPFK_00536 7.3e-10
FADFFPFK_00538 2.1e-50
FADFFPFK_00539 6.5e-76
FADFFPFK_00540 4.8e-239 ywqJ S Pre-toxin TG
FADFFPFK_00541 3.9e-38 ywqI S Family of unknown function (DUF5344)
FADFFPFK_00542 5.9e-20 S Domain of unknown function (DUF5082)
FADFFPFK_00543 1.6e-151 ywqG S Domain of unknown function (DUF1963)
FADFFPFK_00544 1.2e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FADFFPFK_00545 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
FADFFPFK_00546 2.4e-116 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
FADFFPFK_00547 2e-116 ywqC M biosynthesis protein
FADFFPFK_00548 1.2e-17
FADFFPFK_00549 7.8e-307 ywqB S SWIM zinc finger
FADFFPFK_00550 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
FADFFPFK_00551 3.9e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
FADFFPFK_00552 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
FADFFPFK_00553 3.7e-57 ssbB L Single-stranded DNA-binding protein
FADFFPFK_00554 3.8e-66 ywpG
FADFFPFK_00555 1.1e-66 ywpF S YwpF-like protein
FADFFPFK_00556 3e-84 srtA 3.4.22.70 M Sortase family
FADFFPFK_00557 0.0 M1-568 M cell wall anchor domain
FADFFPFK_00558 5.3e-174 M1-574 T Transcriptional regulatory protein, C terminal
FADFFPFK_00559 0.0 ywpD T PhoQ Sensor
FADFFPFK_00560 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
FADFFPFK_00561 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FADFFPFK_00562 5.7e-197 S aspartate phosphatase
FADFFPFK_00563 8.3e-140 flhP N flagellar basal body
FADFFPFK_00564 5.8e-125 flhO N flagellar basal body
FADFFPFK_00565 3.5e-180 mbl D Rod shape-determining protein
FADFFPFK_00566 3e-44 spoIIID K Stage III sporulation protein D
FADFFPFK_00567 2.1e-70 ywoH K COG1846 Transcriptional regulators
FADFFPFK_00568 1.7e-210 ywoG EGP Major facilitator Superfamily
FADFFPFK_00570 2.3e-225 ywoF P Right handed beta helix region
FADFFPFK_00571 2.8e-279 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
FADFFPFK_00572 9.1e-240 ywoD EGP Major facilitator superfamily
FADFFPFK_00573 6.8e-104 phzA Q Isochorismatase family
FADFFPFK_00574 1.2e-77
FADFFPFK_00575 3.3e-225 amt P Ammonium transporter
FADFFPFK_00576 1.6e-58 nrgB K Belongs to the P(II) protein family
FADFFPFK_00577 1.3e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
FADFFPFK_00578 5.6e-71 ywnJ S VanZ like family
FADFFPFK_00579 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
FADFFPFK_00580 2.7e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
FADFFPFK_00581 3.4e-09 ywnC S Family of unknown function (DUF5362)
FADFFPFK_00582 2.9e-70 ywnF S Family of unknown function (DUF5392)
FADFFPFK_00583 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FADFFPFK_00584 2.2e-142 mta K transcriptional
FADFFPFK_00585 1.7e-58 ywnC S Family of unknown function (DUF5362)
FADFFPFK_00586 1.1e-113 ywnB S NAD(P)H-binding
FADFFPFK_00587 1.7e-64 ywnA K Transcriptional regulator
FADFFPFK_00588 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
FADFFPFK_00589 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
FADFFPFK_00590 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
FADFFPFK_00591 3.8e-11 csbD K CsbD-like
FADFFPFK_00592 3e-84 ywmF S Peptidase M50
FADFFPFK_00593 1.3e-103 S response regulator aspartate phosphatase
FADFFPFK_00594 5.9e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FADFFPFK_00595 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FADFFPFK_00597 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
FADFFPFK_00598 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
FADFFPFK_00599 1.2e-175 spoIID D Stage II sporulation protein D
FADFFPFK_00600 3.9e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FADFFPFK_00601 8.2e-134 ywmB S TATA-box binding
FADFFPFK_00602 1.3e-32 ywzB S membrane
FADFFPFK_00603 4.1e-86 ywmA
FADFFPFK_00604 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
FADFFPFK_00605 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FADFFPFK_00606 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FADFFPFK_00607 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FADFFPFK_00608 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FADFFPFK_00609 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FADFFPFK_00610 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FADFFPFK_00611 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
FADFFPFK_00612 7.4e-62 atpI S ATP synthase
FADFFPFK_00613 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FADFFPFK_00614 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FADFFPFK_00615 7.2e-95 ywlG S Belongs to the UPF0340 family
FADFFPFK_00616 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
FADFFPFK_00617 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FADFFPFK_00618 1.7e-91 mntP P Probably functions as a manganese efflux pump
FADFFPFK_00619 1.8e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FADFFPFK_00620 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
FADFFPFK_00621 6.1e-112 spoIIR S stage II sporulation protein R
FADFFPFK_00622 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
FADFFPFK_00624 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FADFFPFK_00625 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FADFFPFK_00626 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FADFFPFK_00627 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
FADFFPFK_00628 8.6e-160 ywkB S Membrane transport protein
FADFFPFK_00629 0.0 sfcA 1.1.1.38 C malic enzyme
FADFFPFK_00630 1.2e-103 tdk 2.7.1.21 F thymidine kinase
FADFFPFK_00631 1.1e-32 rpmE J Binds the 23S rRNA
FADFFPFK_00632 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FADFFPFK_00633 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
FADFFPFK_00634 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FADFFPFK_00635 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FADFFPFK_00636 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
FADFFPFK_00637 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
FADFFPFK_00638 1.8e-90 ywjG S Domain of unknown function (DUF2529)
FADFFPFK_00639 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
FADFFPFK_00640 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
FADFFPFK_00641 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
FADFFPFK_00642 0.0 fadF C COG0247 Fe-S oxidoreductase
FADFFPFK_00643 8.3e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
FADFFPFK_00644 3.6e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
FADFFPFK_00645 2.7e-42 ywjC
FADFFPFK_00646 2.5e-92 ywjB H RibD C-terminal domain
FADFFPFK_00647 0.0 ywjA V ABC transporter
FADFFPFK_00648 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FADFFPFK_00649 1.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
FADFFPFK_00650 1.2e-92 narJ 1.7.5.1 C nitrate reductase
FADFFPFK_00651 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
FADFFPFK_00652 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FADFFPFK_00653 4.5e-85 arfM T cyclic nucleotide binding
FADFFPFK_00654 8.2e-139 ywiC S YwiC-like protein
FADFFPFK_00655 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
FADFFPFK_00656 3.3e-212 narK P COG2223 Nitrate nitrite transporter
FADFFPFK_00657 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
FADFFPFK_00658 4.7e-73 ywiB S protein conserved in bacteria
FADFFPFK_00659 1e-07 S Bacteriocin subtilosin A
FADFFPFK_00660 3.8e-270 C Fe-S oxidoreductases
FADFFPFK_00662 2.8e-131 cbiO V ABC transporter
FADFFPFK_00663 9.4e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
FADFFPFK_00664 1.9e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
FADFFPFK_00665 6.1e-246 L Peptidase, M16
FADFFPFK_00667 4.3e-229 ywhL CO amine dehydrogenase activity
FADFFPFK_00668 5.6e-189 ywhK CO amine dehydrogenase activity
FADFFPFK_00669 3.1e-79 S aspartate phosphatase
FADFFPFK_00671 5.5e-61 ywhH S Aminoacyl-tRNA editing domain
FADFFPFK_00672 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
FADFFPFK_00673 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FADFFPFK_00674 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
FADFFPFK_00675 2.2e-93 ywhD S YwhD family
FADFFPFK_00676 5.1e-119 ywhC S Peptidase family M50
FADFFPFK_00677 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
FADFFPFK_00678 3.3e-71 ywhA K Transcriptional regulator
FADFFPFK_00679 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FADFFPFK_00681 3e-238 mmr U Major Facilitator Superfamily
FADFFPFK_00682 6.2e-79 yffB K Transcriptional regulator
FADFFPFK_00683 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
FADFFPFK_00684 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
FADFFPFK_00685 3.1e-36 ywzC S Belongs to the UPF0741 family
FADFFPFK_00686 1e-110 rsfA_1
FADFFPFK_00687 1.5e-158 ywfM EG EamA-like transporter family
FADFFPFK_00688 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
FADFFPFK_00689 1.1e-156 cysL K Transcriptional regulator
FADFFPFK_00690 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
FADFFPFK_00691 3.3e-146 ywfI C May function as heme-dependent peroxidase
FADFFPFK_00692 7.5e-138 IQ Enoyl-(Acyl carrier protein) reductase
FADFFPFK_00693 6e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
FADFFPFK_00694 1.9e-209 bacE EGP Major facilitator Superfamily
FADFFPFK_00695 1.8e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
FADFFPFK_00696 1.9e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FADFFPFK_00697 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
FADFFPFK_00698 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
FADFFPFK_00699 6e-206 ywfA EGP Major facilitator Superfamily
FADFFPFK_00700 7.4e-250 lysP E amino acid
FADFFPFK_00701 0.0 rocB E arginine degradation protein
FADFFPFK_00702 6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
FADFFPFK_00703 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
FADFFPFK_00704 5.8e-77
FADFFPFK_00705 1.3e-86 spsL 5.1.3.13 M Spore Coat
FADFFPFK_00706 1.9e-158 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
FADFFPFK_00707 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
FADFFPFK_00708 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FADFFPFK_00709 7.9e-188 spsG M Spore Coat
FADFFPFK_00710 9.7e-132 spsF M Spore Coat
FADFFPFK_00711 3.5e-213 spsE 2.5.1.56 M acid synthase
FADFFPFK_00712 2.2e-162 spsD 2.3.1.210 K Spore Coat
FADFFPFK_00713 2.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
FADFFPFK_00714 5.6e-269 spsB M Capsule polysaccharide biosynthesis protein
FADFFPFK_00715 2.6e-143 spsA M Spore Coat
FADFFPFK_00716 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
FADFFPFK_00717 4.3e-59 ywdK S small membrane protein
FADFFPFK_00718 3.7e-238 ywdJ F Xanthine uracil
FADFFPFK_00719 7.7e-49 ywdI S Family of unknown function (DUF5327)
FADFFPFK_00720 7.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
FADFFPFK_00721 1.5e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FADFFPFK_00722 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
FADFFPFK_00724 4.9e-111 ywdD
FADFFPFK_00725 1.3e-57 pex K Transcriptional regulator PadR-like family
FADFFPFK_00726 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
FADFFPFK_00727 2e-28 ywdA
FADFFPFK_00728 7e-291 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
FADFFPFK_00729 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FADFFPFK_00730 5.7e-138 focA P Formate/nitrite transporter
FADFFPFK_00731 7e-150 sacT K transcriptional antiterminator
FADFFPFK_00733 0.0 vpr O Belongs to the peptidase S8 family
FADFFPFK_00734 8.9e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FADFFPFK_00735 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
FADFFPFK_00736 8.6e-202 rodA D Belongs to the SEDS family
FADFFPFK_00737 3e-204 S Acetyltransferase
FADFFPFK_00738 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
FADFFPFK_00739 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
FADFFPFK_00740 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
FADFFPFK_00741 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FADFFPFK_00742 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
FADFFPFK_00743 1e-35 ywzA S membrane
FADFFPFK_00744 3.5e-296 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
FADFFPFK_00745 1.2e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FADFFPFK_00746 2.8e-59 gtcA S GtrA-like protein
FADFFPFK_00747 1.1e-121 ywcC K transcriptional regulator
FADFFPFK_00749 9.8e-49 ywcB S Protein of unknown function, DUF485
FADFFPFK_00750 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FADFFPFK_00751 1.3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
FADFFPFK_00752 9.3e-223 ywbN P Dyp-type peroxidase family protein
FADFFPFK_00753 3.5e-184 ycdO P periplasmic lipoprotein involved in iron transport
FADFFPFK_00754 5.1e-249 P COG0672 High-affinity Fe2 Pb2 permease
FADFFPFK_00755 1.4e-111 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
FADFFPFK_00756 2.6e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FADFFPFK_00757 1.6e-152 ywbI K Transcriptional regulator
FADFFPFK_00758 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
FADFFPFK_00759 2.3e-111 ywbG M effector of murein hydrolase
FADFFPFK_00760 3.1e-207 ywbF EGP Major facilitator Superfamily
FADFFPFK_00761 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
FADFFPFK_00762 5.4e-220 ywbD 2.1.1.191 J Methyltransferase
FADFFPFK_00763 9.9e-67 ywbC 4.4.1.5 E glyoxalase
FADFFPFK_00764 1.9e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FADFFPFK_00765 1.2e-242 epr 3.4.21.62 O Belongs to the peptidase S8 family
FADFFPFK_00766 2.6e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FADFFPFK_00767 1.3e-148 sacY K transcriptional antiterminator
FADFFPFK_00768 4.5e-168 gspA M General stress
FADFFPFK_00769 2.1e-123 ywaF S Integral membrane protein
FADFFPFK_00770 4e-87 ywaE K Transcriptional regulator
FADFFPFK_00771 5e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FADFFPFK_00772 1.3e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
FADFFPFK_00773 8.1e-93 K Helix-turn-helix XRE-family like proteins
FADFFPFK_00774 5.5e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
FADFFPFK_00775 6.8e-130 ynfM EGP Major facilitator Superfamily
FADFFPFK_00776 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
FADFFPFK_00777 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
FADFFPFK_00778 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
FADFFPFK_00779 8.7e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FADFFPFK_00780 1.2e-232 dltB M membrane protein involved in D-alanine export
FADFFPFK_00781 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FADFFPFK_00782 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FADFFPFK_00783 2.8e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
FADFFPFK_00784 6.9e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
FADFFPFK_00785 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
FADFFPFK_00786 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
FADFFPFK_00787 2e-247 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FADFFPFK_00788 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
FADFFPFK_00789 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
FADFFPFK_00790 1.1e-19 yxzF
FADFFPFK_00791 5e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
FADFFPFK_00792 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
FADFFPFK_00793 1.3e-208 yxlH EGP Major facilitator Superfamily
FADFFPFK_00794 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FADFFPFK_00795 5.3e-164 yxlF V ABC transporter, ATP-binding protein
FADFFPFK_00796 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
FADFFPFK_00797 1.4e-30
FADFFPFK_00798 3.9e-48 yxlC S Family of unknown function (DUF5345)
FADFFPFK_00799 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
FADFFPFK_00800 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
FADFFPFK_00801 7.7e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FADFFPFK_00802 0.0 cydD V ATP-binding protein
FADFFPFK_00803 1e-309 cydD V ATP-binding
FADFFPFK_00804 1.1e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
FADFFPFK_00805 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
FADFFPFK_00806 1.5e-229 cimH C COG3493 Na citrate symporter
FADFFPFK_00807 4.7e-310 3.4.24.84 O Peptidase family M48
FADFFPFK_00809 1.4e-153 yxkH G Polysaccharide deacetylase
FADFFPFK_00810 5.9e-205 msmK P Belongs to the ABC transporter superfamily
FADFFPFK_00811 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
FADFFPFK_00812 2.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FADFFPFK_00813 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FADFFPFK_00814 1.4e-73 yxkC S Domain of unknown function (DUF4352)
FADFFPFK_00815 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
FADFFPFK_00816 2e-77 S Protein of unknown function (DUF1453)
FADFFPFK_00817 9.2e-191 yxjM T Signal transduction histidine kinase
FADFFPFK_00818 8.3e-114 K helix_turn_helix, Lux Regulon
FADFFPFK_00819 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
FADFFPFK_00822 1.3e-84 yxjI S LURP-one-related
FADFFPFK_00823 1.9e-219 yxjG 2.1.1.14 E Methionine synthase
FADFFPFK_00824 1.1e-217 yxjG 2.1.1.14 E Methionine synthase
FADFFPFK_00825 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
FADFFPFK_00826 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
FADFFPFK_00827 2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FADFFPFK_00828 1.7e-252 yxjC EG COG2610 H gluconate symporter and related permeases
FADFFPFK_00829 3.2e-158 rlmA 2.1.1.187 Q Methyltransferase domain
FADFFPFK_00830 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FADFFPFK_00831 7.2e-105 T Domain of unknown function (DUF4163)
FADFFPFK_00832 8.7e-47 yxiS
FADFFPFK_00833 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
FADFFPFK_00834 6.6e-224 citH C Citrate transporter
FADFFPFK_00835 1.1e-143 exoK GH16 M licheninase activity
FADFFPFK_00836 8.3e-151 licT K transcriptional antiterminator
FADFFPFK_00837 2e-110
FADFFPFK_00838 1.9e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
FADFFPFK_00839 1.9e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
FADFFPFK_00840 4e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
FADFFPFK_00843 2.8e-45 yxiJ S YxiJ-like protein
FADFFPFK_00844 6.3e-54 yxiI S Protein of unknown function (DUF2716)
FADFFPFK_00845 7.4e-139
FADFFPFK_00846 5.1e-69 yxiG
FADFFPFK_00847 7.3e-59
FADFFPFK_00848 1.7e-84
FADFFPFK_00849 1.5e-71 yxxG
FADFFPFK_00850 0.0 wapA M COG3209 Rhs family protein
FADFFPFK_00851 1.9e-164 yxxF EG EamA-like transporter family
FADFFPFK_00852 5.4e-72 yxiE T Belongs to the universal stress protein A family
FADFFPFK_00853 2e-277 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FADFFPFK_00854 2.6e-306 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FADFFPFK_00855 5.5e-53
FADFFPFK_00856 6.4e-216 S nuclease activity
FADFFPFK_00857 1.4e-38 yxiC S Family of unknown function (DUF5344)
FADFFPFK_00858 2.3e-20 S Domain of unknown function (DUF5082)
FADFFPFK_00859 0.0 L HKD family nuclease
FADFFPFK_00861 1.1e-58 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
FADFFPFK_00862 2.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
FADFFPFK_00863 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
FADFFPFK_00864 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
FADFFPFK_00865 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FADFFPFK_00866 4.4e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
FADFFPFK_00867 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
FADFFPFK_00868 3.4e-250 lysP E amino acid
FADFFPFK_00869 8.7e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
FADFFPFK_00870 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FADFFPFK_00871 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FADFFPFK_00872 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
FADFFPFK_00873 2e-152 yxxB S Domain of Unknown Function (DUF1206)
FADFFPFK_00874 1.1e-195 eutH E Ethanolamine utilisation protein, EutH
FADFFPFK_00875 8.6e-251 yxeQ S MmgE/PrpD family
FADFFPFK_00876 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
FADFFPFK_00877 1.7e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
FADFFPFK_00878 1.2e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
FADFFPFK_00879 4.6e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
FADFFPFK_00880 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FADFFPFK_00881 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FADFFPFK_00882 1.4e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
FADFFPFK_00883 1.5e-149 yidA S hydrolases of the HAD superfamily
FADFFPFK_00886 1.3e-20 yxeE
FADFFPFK_00887 5.6e-16 yxeD
FADFFPFK_00888 8.5e-69
FADFFPFK_00889 1.1e-175 fhuD P ABC transporter
FADFFPFK_00890 1.3e-57 yxeA S Protein of unknown function (DUF1093)
FADFFPFK_00891 0.0 yxdM V ABC transporter (permease)
FADFFPFK_00892 3.7e-137 yxdL V ABC transporter, ATP-binding protein
FADFFPFK_00893 1e-179 T PhoQ Sensor
FADFFPFK_00894 9.3e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_00895 5.1e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
FADFFPFK_00896 5e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
FADFFPFK_00897 3e-167 iolH G Xylose isomerase-like TIM barrel
FADFFPFK_00898 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
FADFFPFK_00899 9.6e-234 iolF EGP Major facilitator Superfamily
FADFFPFK_00900 1e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
FADFFPFK_00901 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
FADFFPFK_00902 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
FADFFPFK_00903 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
FADFFPFK_00904 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FADFFPFK_00905 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
FADFFPFK_00906 4.1e-175 iolS C Aldo keto reductase
FADFFPFK_00908 8.3e-48 yxcD S Protein of unknown function (DUF2653)
FADFFPFK_00909 1.5e-245 csbC EGP Major facilitator Superfamily
FADFFPFK_00910 0.0 htpG O Molecular chaperone. Has ATPase activity
FADFFPFK_00912 3.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
FADFFPFK_00913 6.2e-197 yxbF K Bacterial regulatory proteins, tetR family
FADFFPFK_00914 1.5e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
FADFFPFK_00915 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
FADFFPFK_00916 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
FADFFPFK_00917 1.3e-126 yxbB Q Met-10+ like-protein
FADFFPFK_00918 1.9e-43 S Coenzyme PQQ synthesis protein D (PqqD)
FADFFPFK_00919 1.1e-86 yxnB
FADFFPFK_00920 0.0 asnB 6.3.5.4 E Asparagine synthase
FADFFPFK_00921 3.8e-213 yxaM U MFS_1 like family
FADFFPFK_00922 1.1e-90 S PQQ-like domain
FADFFPFK_00923 1.1e-63 S Family of unknown function (DUF5391)
FADFFPFK_00924 1.4e-75 yxaI S membrane protein domain
FADFFPFK_00925 2.5e-225 P Protein of unknown function (DUF418)
FADFFPFK_00926 8.4e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
FADFFPFK_00927 2.7e-100 yxaF K Transcriptional regulator
FADFFPFK_00928 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FADFFPFK_00929 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
FADFFPFK_00930 5.2e-50 S LrgA family
FADFFPFK_00931 2.6e-118 yxaC M effector of murein hydrolase
FADFFPFK_00932 5.9e-191 yxaB GM Polysaccharide pyruvyl transferase
FADFFPFK_00933 4.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
FADFFPFK_00934 7.3e-127 gntR K transcriptional
FADFFPFK_00935 8.6e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
FADFFPFK_00936 7.7e-231 gntP EG COG2610 H gluconate symporter and related permeases
FADFFPFK_00937 7.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FADFFPFK_00938 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
FADFFPFK_00939 1.2e-285 ahpF O Alkyl hydroperoxide reductase
FADFFPFK_00940 8.1e-188 wgaE S Polysaccharide pyruvyl transferase
FADFFPFK_00941 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FADFFPFK_00942 3.2e-25 bglF G phosphotransferase system
FADFFPFK_00943 2.4e-19 bglF G phosphotransferase system
FADFFPFK_00944 3.7e-123 yydK K Transcriptional regulator
FADFFPFK_00945 2.2e-12
FADFFPFK_00946 1.5e-116 S ABC-2 family transporter protein
FADFFPFK_00947 1.6e-109 prrC P ABC transporter
FADFFPFK_00948 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
FADFFPFK_00949 3.2e-189 2.7.7.49 L Reverse transcriptase (RNA-dependent DNA polymerase)
FADFFPFK_00950 4.4e-112 K competence protein
FADFFPFK_00951 4.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FADFFPFK_00952 1.1e-09 S YyzF-like protein
FADFFPFK_00953 8.2e-59
FADFFPFK_00954 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
FADFFPFK_00956 5.7e-31 yycQ S Protein of unknown function (DUF2651)
FADFFPFK_00957 3.9e-207 yycP
FADFFPFK_00958 1.2e-129 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FADFFPFK_00959 4.5e-85 yycN 2.3.1.128 K Acetyltransferase
FADFFPFK_00960 1.1e-187 S aspartate phosphatase
FADFFPFK_00962 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
FADFFPFK_00963 7.2e-256 rocE E amino acid
FADFFPFK_00964 9.6e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
FADFFPFK_00965 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
FADFFPFK_00966 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
FADFFPFK_00967 1.5e-94 K PFAM response regulator receiver
FADFFPFK_00968 4e-74 S Peptidase propeptide and YPEB domain
FADFFPFK_00969 1.1e-17 S Peptidase propeptide and YPEB domain
FADFFPFK_00970 4.3e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FADFFPFK_00971 3.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
FADFFPFK_00972 7.3e-155 yycI S protein conserved in bacteria
FADFFPFK_00973 3.2e-256 yycH S protein conserved in bacteria
FADFFPFK_00974 0.0 vicK 2.7.13.3 T Histidine kinase
FADFFPFK_00975 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_00980 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FADFFPFK_00981 2e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FADFFPFK_00982 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
FADFFPFK_00983 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
FADFFPFK_00985 1.9e-15 yycC K YycC-like protein
FADFFPFK_00986 2.5e-220 yeaN P COG2807 Cyanate permease
FADFFPFK_00987 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FADFFPFK_00988 2.2e-73 rplI J binds to the 23S rRNA
FADFFPFK_00989 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
FADFFPFK_00990 8.3e-160 yybS S membrane
FADFFPFK_00992 3.9e-84 cotF M Spore coat protein
FADFFPFK_00993 4.9e-66 ydeP3 K Transcriptional regulator
FADFFPFK_00994 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
FADFFPFK_00995 1.9e-61
FADFFPFK_00997 3.9e-240 yybO G COG0477 Permeases of the major facilitator superfamily
FADFFPFK_00998 4.3e-111 K TipAS antibiotic-recognition domain
FADFFPFK_00999 9e-123
FADFFPFK_01000 1e-66 yybH S SnoaL-like domain
FADFFPFK_01001 5.3e-121 yybG S Pentapeptide repeat-containing protein
FADFFPFK_01002 2.2e-216 ynfM EGP Major facilitator Superfamily
FADFFPFK_01003 2.6e-163 yybE K Transcriptional regulator
FADFFPFK_01004 2e-79 yjcF S Acetyltransferase (GNAT) domain
FADFFPFK_01005 2.3e-76 yybC
FADFFPFK_01006 3e-127 S Metallo-beta-lactamase superfamily
FADFFPFK_01007 5.6e-77 yybA 2.3.1.57 K transcriptional
FADFFPFK_01008 1.3e-70 yjcF S Acetyltransferase (GNAT) domain
FADFFPFK_01009 5.5e-96 yyaS S Membrane
FADFFPFK_01010 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
FADFFPFK_01011 7.8e-66 yyaQ S YjbR
FADFFPFK_01012 3.6e-105 yyaP 1.5.1.3 H RibD C-terminal domain
FADFFPFK_01013 6.6e-246 tetL EGP Major facilitator Superfamily
FADFFPFK_01014 1.2e-41 yyaL O Highly conserved protein containing a thioredoxin domain
FADFFPFK_01015 2.5e-60 yyaN K MerR HTH family regulatory protein
FADFFPFK_01016 6.3e-160 yyaM EG EamA-like transporter family
FADFFPFK_01017 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
FADFFPFK_01018 4.4e-166 yyaK S CAAX protease self-immunity
FADFFPFK_01019 1.8e-243 EGP Major facilitator superfamily
FADFFPFK_01020 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
FADFFPFK_01021 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FADFFPFK_01022 2.6e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
FADFFPFK_01023 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
FADFFPFK_01024 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FADFFPFK_01025 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FADFFPFK_01026 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
FADFFPFK_01027 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FADFFPFK_01028 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FADFFPFK_01029 2.3e-33 yyzM S protein conserved in bacteria
FADFFPFK_01030 2e-175 yyaD S Membrane
FADFFPFK_01031 1.6e-111 yyaC S Sporulation protein YyaC
FADFFPFK_01032 2.1e-149 spo0J K Belongs to the ParB family
FADFFPFK_01033 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
FADFFPFK_01034 1.3e-73 S Bacterial PH domain
FADFFPFK_01035 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
FADFFPFK_01036 2.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
FADFFPFK_01037 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
FADFFPFK_01038 5.4e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FADFFPFK_01039 1.5e-107 jag S single-stranded nucleic acid binding R3H
FADFFPFK_01040 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FADFFPFK_01041 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
FADFFPFK_01042 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FADFFPFK_01043 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FADFFPFK_01044 2.4e-33 yaaA S S4 domain
FADFFPFK_01045 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FADFFPFK_01046 1.8e-37 yaaB S Domain of unknown function (DUF370)
FADFFPFK_01047 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FADFFPFK_01048 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FADFFPFK_01049 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FADFFPFK_01050 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FADFFPFK_01051 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
FADFFPFK_01052 4e-63 yngL S Protein of unknown function (DUF1360)
FADFFPFK_01053 2.9e-303 yngK T Glycosyl hydrolase-like 10
FADFFPFK_01054 1.6e-11 K Bacterial regulatory proteins, tetR family
FADFFPFK_01056 6.3e-32 S Family of unknown function (DUF5367)
FADFFPFK_01057 9.8e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
FADFFPFK_01058 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
FADFFPFK_01059 1.4e-248 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
FADFFPFK_01060 6.6e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
FADFFPFK_01061 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
FADFFPFK_01062 2.3e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
FADFFPFK_01063 6.6e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
FADFFPFK_01064 3.6e-232 nrnB S phosphohydrolase (DHH superfamily)
FADFFPFK_01065 5.5e-104 yngC S membrane-associated protein
FADFFPFK_01066 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FADFFPFK_01067 1.6e-79 yngA S membrane
FADFFPFK_01068 4.4e-291 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
FADFFPFK_01069 7.2e-247 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
FADFFPFK_01070 2.6e-211 S Platelet-activating factor acetylhydrolase, isoform II
FADFFPFK_01072 1.4e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
FADFFPFK_01073 5.3e-251 agcS E Sodium alanine symporter
FADFFPFK_01074 1.3e-57 ynfC
FADFFPFK_01075 2.3e-12
FADFFPFK_01076 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FADFFPFK_01077 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FADFFPFK_01078 6.6e-69 yccU S CoA-binding protein
FADFFPFK_01079 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FADFFPFK_01080 4.1e-49 yneR S Belongs to the HesB IscA family
FADFFPFK_01081 2.2e-53 yneQ
FADFFPFK_01082 1.2e-73 yneP S Thioesterase-like superfamily
FADFFPFK_01083 3.9e-35 tlp S Belongs to the Tlp family
FADFFPFK_01084 3.1e-08 sspN S Small acid-soluble spore protein N family
FADFFPFK_01086 6.5e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FADFFPFK_01087 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FADFFPFK_01088 2.2e-14 sspO S Belongs to the SspO family
FADFFPFK_01089 3.9e-19 sspP S Belongs to the SspP family
FADFFPFK_01090 5.9e-64 hspX O Spore coat protein
FADFFPFK_01091 4.2e-74 yneK S Protein of unknown function (DUF2621)
FADFFPFK_01092 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
FADFFPFK_01093 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
FADFFPFK_01094 7.8e-126 ccdA O cytochrome c biogenesis protein
FADFFPFK_01095 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
FADFFPFK_01096 1.8e-28 yneF S UPF0154 protein
FADFFPFK_01097 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
FADFFPFK_01098 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FADFFPFK_01099 4.8e-32 ynzC S UPF0291 protein
FADFFPFK_01100 3.6e-109 yneB L resolvase
FADFFPFK_01101 7.6e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
FADFFPFK_01102 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FADFFPFK_01103 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
FADFFPFK_01104 5.8e-74 yndM S Protein of unknown function (DUF2512)
FADFFPFK_01105 4.7e-137 yndL S Replication protein
FADFFPFK_01107 2.7e-307 yndJ S YndJ-like protein
FADFFPFK_01108 7.1e-115 yndH S Domain of unknown function (DUF4166)
FADFFPFK_01109 1.2e-149 yndG S DoxX-like family
FADFFPFK_01110 4.1e-215 gerLC S Spore germination protein
FADFFPFK_01111 3.6e-194 gerAB U Spore germination
FADFFPFK_01112 3.2e-281 gerAA EG Spore germination protein
FADFFPFK_01115 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
FADFFPFK_01116 1.8e-71
FADFFPFK_01117 7.9e-25 tatA U protein secretion
FADFFPFK_01120 4.9e-134 S Domain of unknown function, YrpD
FADFFPFK_01122 3e-164 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FADFFPFK_01125 5.2e-15
FADFFPFK_01126 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
FADFFPFK_01127 5e-81 yncE S Protein of unknown function (DUF2691)
FADFFPFK_01129 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FADFFPFK_01130 2.2e-252 iolT EGP Major facilitator Superfamily
FADFFPFK_01131 3.4e-112 yokF 3.1.31.1 L RNA catabolic process
FADFFPFK_01132 3.6e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
FADFFPFK_01133 2.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
FADFFPFK_01134 8.1e-213 xylR GK ROK family
FADFFPFK_01135 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
FADFFPFK_01136 6e-255 xynT G MFS/sugar transport protein
FADFFPFK_01137 5.5e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
FADFFPFK_01140 1.3e-77 S CAAX protease self-immunity
FADFFPFK_01142 6.8e-98 ynaD J Acetyltransferase (GNAT) domain
FADFFPFK_01143 1.3e-08 S Protein of unknown function (DUF1433)
FADFFPFK_01144 2.1e-103 ynaC
FADFFPFK_01145 1.1e-10 ynaC
FADFFPFK_01146 9.8e-89 G SMI1-KNR4 cell-wall
FADFFPFK_01147 3.2e-37
FADFFPFK_01148 4.6e-31
FADFFPFK_01149 3.8e-10
FADFFPFK_01151 3.7e-77 M nucleic acid phosphodiester bond hydrolysis
FADFFPFK_01152 5.5e-124 M nucleic acid phosphodiester bond hydrolysis
FADFFPFK_01153 3e-31
FADFFPFK_01154 7e-261 glnA 6.3.1.2 E glutamine synthetase
FADFFPFK_01155 1.1e-68 glnR K transcriptional
FADFFPFK_01156 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
FADFFPFK_01157 7.9e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FADFFPFK_01158 1.7e-176 spoVK O stage V sporulation protein K
FADFFPFK_01159 8.8e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FADFFPFK_01160 2e-109 ymaB
FADFFPFK_01161 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FADFFPFK_01162 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FADFFPFK_01163 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
FADFFPFK_01164 4.5e-22 ymzA
FADFFPFK_01165 8.2e-23
FADFFPFK_01166 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
FADFFPFK_01167 2.3e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FADFFPFK_01168 2.1e-46 ymaF S YmaF family
FADFFPFK_01170 4.1e-50 ebrA P Small Multidrug Resistance protein
FADFFPFK_01171 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
FADFFPFK_01172 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
FADFFPFK_01173 2.1e-126 ymaC S Replication protein
FADFFPFK_01174 1.9e-07 K Transcriptional regulator
FADFFPFK_01175 8.6e-251 aprX O Belongs to the peptidase S8 family
FADFFPFK_01176 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
FADFFPFK_01177 6.4e-60 ymzB
FADFFPFK_01178 1.8e-231 cypA C Cytochrome P450
FADFFPFK_01179 0.0 pks13 HQ Beta-ketoacyl synthase
FADFFPFK_01180 0.0 dhbF IQ polyketide synthase
FADFFPFK_01181 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
FADFFPFK_01182 0.0 pfaA Q Polyketide synthase of type I
FADFFPFK_01183 0.0 rhiB IQ polyketide synthase
FADFFPFK_01184 6.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
FADFFPFK_01185 2.5e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
FADFFPFK_01186 1.5e-244 pksG 2.3.3.10 I synthase
FADFFPFK_01187 6.6e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FADFFPFK_01188 1.4e-37 acpK IQ Phosphopantetheine attachment site
FADFFPFK_01189 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
FADFFPFK_01190 1.7e-184 pksD Q Acyl transferase domain
FADFFPFK_01192 7.5e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
FADFFPFK_01193 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
FADFFPFK_01194 4.4e-109 pksA K Transcriptional regulator
FADFFPFK_01195 3.5e-97 ymcC S Membrane
FADFFPFK_01197 4.1e-67 S Regulatory protein YrvL
FADFFPFK_01198 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FADFFPFK_01199 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FADFFPFK_01200 2.2e-88 cotE S Spore coat protein
FADFFPFK_01201 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
FADFFPFK_01202 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FADFFPFK_01203 1.4e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
FADFFPFK_01204 3.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
FADFFPFK_01205 1.2e-36 spoVS S Stage V sporulation protein S
FADFFPFK_01206 1.9e-152 ymdB S protein conserved in bacteria
FADFFPFK_01207 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
FADFFPFK_01208 2.6e-214 pbpX V Beta-lactamase
FADFFPFK_01209 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FADFFPFK_01210 5.6e-236 cinA 3.5.1.42 S Belongs to the CinA family
FADFFPFK_01211 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FADFFPFK_01212 3.5e-118 ymfM S protein conserved in bacteria
FADFFPFK_01213 2.7e-143 ymfK S Protein of unknown function (DUF3388)
FADFFPFK_01214 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
FADFFPFK_01215 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
FADFFPFK_01216 1.1e-239 ymfH S zinc protease
FADFFPFK_01217 7.8e-233 ymfF S Peptidase M16
FADFFPFK_01218 1.5e-206 ymfD EGP Major facilitator Superfamily
FADFFPFK_01219 1.4e-133 ymfC K Transcriptional regulator
FADFFPFK_01220 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
FADFFPFK_01221 4.4e-32 S YlzJ-like protein
FADFFPFK_01222 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
FADFFPFK_01223 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FADFFPFK_01224 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FADFFPFK_01225 8.5e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
FADFFPFK_01226 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FADFFPFK_01227 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
FADFFPFK_01228 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
FADFFPFK_01229 2.6e-42 ymxH S YlmC YmxH family
FADFFPFK_01230 4.4e-233 pepR S Belongs to the peptidase M16 family
FADFFPFK_01231 2.8e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
FADFFPFK_01232 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
FADFFPFK_01233 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FADFFPFK_01234 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
FADFFPFK_01235 5.6e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FADFFPFK_01236 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FADFFPFK_01237 3e-44 ylxP S protein conserved in bacteria
FADFFPFK_01238 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FADFFPFK_01239 3.1e-47 ylxQ J ribosomal protein
FADFFPFK_01240 1.3e-31 ylxR K nucleic-acid-binding protein implicated in transcription termination
FADFFPFK_01241 1.1e-203 nusA K Participates in both transcription termination and antitermination
FADFFPFK_01242 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
FADFFPFK_01243 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FADFFPFK_01244 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
FADFFPFK_01245 1.7e-232 rasP M zinc metalloprotease
FADFFPFK_01246 1.3e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
FADFFPFK_01247 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
FADFFPFK_01248 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FADFFPFK_01249 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FADFFPFK_01250 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
FADFFPFK_01251 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FADFFPFK_01252 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
FADFFPFK_01253 3.1e-76 ylxL
FADFFPFK_01254 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FADFFPFK_01255 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
FADFFPFK_01256 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
FADFFPFK_01257 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
FADFFPFK_01258 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
FADFFPFK_01259 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
FADFFPFK_01260 8.3e-157 flhG D Belongs to the ParA family
FADFFPFK_01261 7.5e-200 flhF N Flagellar biosynthesis regulator FlhF
FADFFPFK_01262 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FADFFPFK_01263 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FADFFPFK_01264 3.6e-132 fliR N Flagellar biosynthetic protein FliR
FADFFPFK_01265 2.2e-36 fliQ N Role in flagellar biosynthesis
FADFFPFK_01266 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
FADFFPFK_01267 1.9e-94 fliZ N Flagellar biosynthesis protein, FliO
FADFFPFK_01268 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
FADFFPFK_01269 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FADFFPFK_01270 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
FADFFPFK_01271 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
FADFFPFK_01272 1.9e-136 flgG N Flagellar basal body rod
FADFFPFK_01273 2.3e-72 flgD N Flagellar basal body rod modification protein
FADFFPFK_01274 7.1e-214 fliK N Flagellar hook-length control protein
FADFFPFK_01275 7.7e-37 ylxF S MgtE intracellular N domain
FADFFPFK_01276 1.5e-69 fliJ N Flagellar biosynthesis chaperone
FADFFPFK_01277 1.8e-240 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
FADFFPFK_01278 7.4e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
FADFFPFK_01279 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
FADFFPFK_01280 2.9e-253 fliF N The M ring may be actively involved in energy transduction
FADFFPFK_01281 1.9e-31 fliE N Flagellar hook-basal body
FADFFPFK_01282 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
FADFFPFK_01283 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
FADFFPFK_01284 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FADFFPFK_01285 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FADFFPFK_01286 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FADFFPFK_01287 2.5e-169 xerC L tyrosine recombinase XerC
FADFFPFK_01288 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FADFFPFK_01289 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FADFFPFK_01290 3e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
FADFFPFK_01291 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FADFFPFK_01292 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
FADFFPFK_01293 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
FADFFPFK_01294 6.9e-285 ylqG
FADFFPFK_01295 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FADFFPFK_01296 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FADFFPFK_01297 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FADFFPFK_01298 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
FADFFPFK_01299 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FADFFPFK_01300 1.4e-60 ylqD S YlqD protein
FADFFPFK_01301 4.5e-36 ylqC S Belongs to the UPF0109 family
FADFFPFK_01302 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
FADFFPFK_01303 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FADFFPFK_01304 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FADFFPFK_01305 2.9e-87
FADFFPFK_01306 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FADFFPFK_01307 0.0 smc D Required for chromosome condensation and partitioning
FADFFPFK_01308 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FADFFPFK_01309 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
FADFFPFK_01310 5.1e-128 IQ reductase
FADFFPFK_01311 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
FADFFPFK_01312 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FADFFPFK_01313 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
FADFFPFK_01314 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FADFFPFK_01315 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
FADFFPFK_01316 5.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
FADFFPFK_01317 7.3e-300 yloV S kinase related to dihydroxyacetone kinase
FADFFPFK_01318 2.7e-58 asp S protein conserved in bacteria
FADFFPFK_01319 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
FADFFPFK_01320 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
FADFFPFK_01321 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
FADFFPFK_01322 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FADFFPFK_01323 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
FADFFPFK_01324 1.6e-140 stp 3.1.3.16 T phosphatase
FADFFPFK_01325 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FADFFPFK_01326 4.6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FADFFPFK_01327 5.5e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FADFFPFK_01328 7.3e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FADFFPFK_01329 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FADFFPFK_01330 2e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FADFFPFK_01331 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
FADFFPFK_01332 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
FADFFPFK_01333 1.5e-40 ylzA S Belongs to the UPF0296 family
FADFFPFK_01334 2.4e-156 yloC S stress-induced protein
FADFFPFK_01335 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
FADFFPFK_01336 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
FADFFPFK_01337 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
FADFFPFK_01338 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
FADFFPFK_01339 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
FADFFPFK_01340 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
FADFFPFK_01341 4.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
FADFFPFK_01342 2.7e-178 cysP P phosphate transporter
FADFFPFK_01343 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
FADFFPFK_01345 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FADFFPFK_01346 3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
FADFFPFK_01347 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FADFFPFK_01348 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
FADFFPFK_01349 0.0 carB 6.3.5.5 F Belongs to the CarB family
FADFFPFK_01350 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FADFFPFK_01351 2e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
FADFFPFK_01352 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
FADFFPFK_01353 7.6e-231 pyrP F Xanthine uracil
FADFFPFK_01354 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FADFFPFK_01355 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FADFFPFK_01356 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FADFFPFK_01357 1.3e-63 dksA T COG1734 DnaK suppressor protein
FADFFPFK_01358 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FADFFPFK_01359 2.6e-67 divIVA D Cell division initiation protein
FADFFPFK_01360 3.3e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
FADFFPFK_01361 1.3e-39 yggT S membrane
FADFFPFK_01362 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
FADFFPFK_01363 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FADFFPFK_01364 9.2e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
FADFFPFK_01365 2.4e-37 ylmC S sporulation protein
FADFFPFK_01366 7.5e-252 argE 3.5.1.16 E Acetylornithine deacetylase
FADFFPFK_01367 1.2e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
FADFFPFK_01368 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FADFFPFK_01369 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FADFFPFK_01370 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
FADFFPFK_01371 0.0 bpr O COG1404 Subtilisin-like serine proteases
FADFFPFK_01372 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FADFFPFK_01373 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FADFFPFK_01374 6.2e-58 sbp S small basic protein
FADFFPFK_01375 1e-102 ylxX S protein conserved in bacteria
FADFFPFK_01376 2.4e-103 ylxW S protein conserved in bacteria
FADFFPFK_01377 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
FADFFPFK_01378 5.3e-167 murB 1.3.1.98 M cell wall formation
FADFFPFK_01379 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FADFFPFK_01380 9.8e-186 spoVE D Belongs to the SEDS family
FADFFPFK_01381 4.5e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FADFFPFK_01382 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FADFFPFK_01383 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FADFFPFK_01384 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
FADFFPFK_01385 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
FADFFPFK_01386 3.7e-44 ftsL D Essential cell division protein
FADFFPFK_01387 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FADFFPFK_01388 2.9e-78 mraZ K Belongs to the MraZ family
FADFFPFK_01389 2.1e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FADFFPFK_01390 4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FADFFPFK_01391 4e-89 ylbP K n-acetyltransferase
FADFFPFK_01392 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
FADFFPFK_01393 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
FADFFPFK_01394 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
FADFFPFK_01396 2.1e-230 ylbM S Belongs to the UPF0348 family
FADFFPFK_01397 7.5e-186 ylbL T Belongs to the peptidase S16 family
FADFFPFK_01398 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
FADFFPFK_01399 1.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
FADFFPFK_01400 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FADFFPFK_01401 1e-96 rsmD 2.1.1.171 L Methyltransferase
FADFFPFK_01402 3.7e-38 ylbG S UPF0298 protein
FADFFPFK_01403 1.8e-75 ylbF S Belongs to the UPF0342 family
FADFFPFK_01404 6.7e-37 ylbE S YlbE-like protein
FADFFPFK_01405 2.9e-61 ylbD S Putative coat protein
FADFFPFK_01406 9.6e-200 ylbC S protein with SCP PR1 domains
FADFFPFK_01407 2.6e-74 ylbB T COG0517 FOG CBS domain
FADFFPFK_01408 7e-62 ylbA S YugN-like family
FADFFPFK_01409 9.8e-166 ctaG S cytochrome c oxidase
FADFFPFK_01410 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
FADFFPFK_01411 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
FADFFPFK_01412 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FADFFPFK_01413 5.2e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
FADFFPFK_01414 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
FADFFPFK_01415 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
FADFFPFK_01416 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FADFFPFK_01417 2.7e-211 ftsW D Belongs to the SEDS family
FADFFPFK_01418 8.7e-44 ylaN S Belongs to the UPF0358 family
FADFFPFK_01419 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
FADFFPFK_01420 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FADFFPFK_01421 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
FADFFPFK_01422 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FADFFPFK_01423 2.5e-32 ylaI S protein conserved in bacteria
FADFFPFK_01424 4.2e-47 ylaH S YlaH-like protein
FADFFPFK_01425 0.0 typA T GTP-binding protein TypA
FADFFPFK_01426 8.2e-22 S Family of unknown function (DUF5325)
FADFFPFK_01427 5.9e-37 ylaE
FADFFPFK_01428 9.1e-12 sigC S Putative zinc-finger
FADFFPFK_01429 2.8e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
FADFFPFK_01430 3e-41 ylaB
FADFFPFK_01431 0.0 ylaA
FADFFPFK_01432 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
FADFFPFK_01433 2.7e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FADFFPFK_01434 2e-77 ykzC S Acetyltransferase (GNAT) family
FADFFPFK_01435 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
FADFFPFK_01436 7.1e-26 ykzI
FADFFPFK_01437 2.1e-117 yktB S Belongs to the UPF0637 family
FADFFPFK_01438 1e-41 yktA S Belongs to the UPF0223 family
FADFFPFK_01439 1e-276 speA 4.1.1.19 E Arginine
FADFFPFK_01440 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
FADFFPFK_01441 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FADFFPFK_01442 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FADFFPFK_01443 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FADFFPFK_01444 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FADFFPFK_01445 6.1e-93 recN L Putative cell-wall binding lipoprotein
FADFFPFK_01447 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FADFFPFK_01448 5.5e-147 ykrA S hydrolases of the HAD superfamily
FADFFPFK_01449 8.2e-31 ykzG S Belongs to the UPF0356 family
FADFFPFK_01450 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FADFFPFK_01451 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FADFFPFK_01452 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
FADFFPFK_01453 2.2e-156 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
FADFFPFK_01454 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
FADFFPFK_01455 1.5e-43 abrB K of stationary sporulation gene expression
FADFFPFK_01456 1.7e-182 mreB D Rod-share determining protein MreBH
FADFFPFK_01457 1.1e-12 S Uncharacterized protein YkpC
FADFFPFK_01458 5.9e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
FADFFPFK_01459 1.2e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FADFFPFK_01460 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FADFFPFK_01461 8.1e-39 ykoA
FADFFPFK_01462 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
FADFFPFK_01463 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
FADFFPFK_01464 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
FADFFPFK_01465 3.1e-136 fruR K Transcriptional regulator
FADFFPFK_01466 2.8e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
FADFFPFK_01467 2.5e-124 macB V ABC transporter, ATP-binding protein
FADFFPFK_01468 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FADFFPFK_01469 3.6e-115 yknW S Yip1 domain
FADFFPFK_01470 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
FADFFPFK_01471 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
FADFFPFK_01472 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FADFFPFK_01473 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
FADFFPFK_01474 3.2e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
FADFFPFK_01475 2.9e-243 moeA 2.10.1.1 H molybdopterin
FADFFPFK_01476 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
FADFFPFK_01477 2.5e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
FADFFPFK_01478 4.2e-146 yknT
FADFFPFK_01479 5.8e-95 rok K Repressor of ComK
FADFFPFK_01480 7e-80 ykuV CO thiol-disulfide
FADFFPFK_01481 3.9e-101 ykuU O Alkyl hydroperoxide reductase
FADFFPFK_01482 8.8e-142 ykuT M Mechanosensitive ion channel
FADFFPFK_01483 9e-37 ykuS S Belongs to the UPF0180 family
FADFFPFK_01484 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
FADFFPFK_01485 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
FADFFPFK_01486 8.7e-78 fld C Flavodoxin
FADFFPFK_01487 1.7e-173 ykuO
FADFFPFK_01488 1.7e-84 fld C Flavodoxin domain
FADFFPFK_01489 3.5e-168 ccpC K Transcriptional regulator
FADFFPFK_01490 1.6e-76 ykuL S CBS domain
FADFFPFK_01491 3.9e-27 ykzF S Antirepressor AbbA
FADFFPFK_01492 1.3e-93 ykuK S Ribonuclease H-like
FADFFPFK_01493 3.9e-37 ykuJ S protein conserved in bacteria
FADFFPFK_01495 5.2e-234 ykuI T Diguanylate phosphodiesterase
FADFFPFK_01496 4.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FADFFPFK_01497 9.4e-166 ykuE S Metallophosphoesterase
FADFFPFK_01498 7.1e-86 ykuD S protein conserved in bacteria
FADFFPFK_01499 2.8e-238 ykuC EGP Major facilitator Superfamily
FADFFPFK_01500 1.7e-84 ykyB S YkyB-like protein
FADFFPFK_01501 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
FADFFPFK_01502 2.2e-15
FADFFPFK_01503 2.4e-220 patA 2.6.1.1 E Aminotransferase
FADFFPFK_01504 0.0 pilS 2.7.13.3 T Histidine kinase
FADFFPFK_01505 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
FADFFPFK_01506 1.8e-123 ykwD J protein with SCP PR1 domains
FADFFPFK_01507 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
FADFFPFK_01508 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
FADFFPFK_01509 9.7e-259 mcpC NT chemotaxis protein
FADFFPFK_01510 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FADFFPFK_01511 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
FADFFPFK_01512 7.2e-39 splA S Transcriptional regulator
FADFFPFK_01513 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FADFFPFK_01514 2.1e-39 ptsH G phosphocarrier protein HPr
FADFFPFK_01515 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FADFFPFK_01516 7.6e-128 glcT K antiterminator
FADFFPFK_01517 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
FADFFPFK_01518 2.8e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
FADFFPFK_01519 2.3e-09
FADFFPFK_01520 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
FADFFPFK_01521 1.6e-88 stoA CO thiol-disulfide
FADFFPFK_01522 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FADFFPFK_01523 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
FADFFPFK_01524 2.8e-28
FADFFPFK_01525 6e-25 ykvS S protein conserved in bacteria
FADFFPFK_01526 2.1e-45 ykvR S Protein of unknown function (DUF3219)
FADFFPFK_01527 1.5e-161 G Glycosyl hydrolases family 18
FADFFPFK_01528 2.3e-34 3.5.1.104 M LysM domain
FADFFPFK_01529 2.9e-215 ykvP 3.5.1.28 M Glycosyl transferases group 1
FADFFPFK_01530 4.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
FADFFPFK_01531 3.4e-61 ykvN K Transcriptional regulator
FADFFPFK_01532 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FADFFPFK_01533 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
FADFFPFK_01534 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
FADFFPFK_01535 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FADFFPFK_01536 3.3e-181 ykvI S membrane
FADFFPFK_01537 0.0 clpE O Belongs to the ClpA ClpB family
FADFFPFK_01538 1e-137 motA N flagellar motor
FADFFPFK_01539 2.5e-125 motB N Flagellar motor protein
FADFFPFK_01540 1.3e-75 ykvE K transcriptional
FADFFPFK_01541 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
FADFFPFK_01542 1.2e-63 eag
FADFFPFK_01543 7.5e-10 S Spo0E like sporulation regulatory protein
FADFFPFK_01544 2.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
FADFFPFK_01545 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FADFFPFK_01546 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
FADFFPFK_01547 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FADFFPFK_01548 4.2e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
FADFFPFK_01549 8.9e-231 mtnE 2.6.1.83 E Aminotransferase
FADFFPFK_01550 8.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
FADFFPFK_01551 1.8e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FADFFPFK_01552 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FADFFPFK_01554 1.6e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FADFFPFK_01555 0.0 kinE 2.7.13.3 T Histidine kinase
FADFFPFK_01556 1.4e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
FADFFPFK_01557 1.4e-18 ykzE
FADFFPFK_01558 1.2e-10 ydfR S Protein of unknown function (DUF421)
FADFFPFK_01559 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
FADFFPFK_01560 3.5e-155 htpX O Belongs to the peptidase M48B family
FADFFPFK_01561 5.6e-124 ykrK S Domain of unknown function (DUF1836)
FADFFPFK_01562 1.9e-26 sspD S small acid-soluble spore protein
FADFFPFK_01563 3.1e-108 rsgI S Anti-sigma factor N-terminus
FADFFPFK_01564 8.1e-129 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FADFFPFK_01565 7.9e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
FADFFPFK_01566 5.4e-110 ykoX S membrane-associated protein
FADFFPFK_01567 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
FADFFPFK_01568 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FADFFPFK_01569 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
FADFFPFK_01570 6.2e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FADFFPFK_01571 0.0 ykoS
FADFFPFK_01572 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
FADFFPFK_01573 1.1e-98 ykoP G polysaccharide deacetylase
FADFFPFK_01574 8.5e-212 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
FADFFPFK_01575 1.3e-81 mhqR K transcriptional
FADFFPFK_01576 6.9e-26 ykoL
FADFFPFK_01577 5.9e-18
FADFFPFK_01578 1.4e-53 tnrA K transcriptional
FADFFPFK_01579 2.2e-222 mgtE P Acts as a magnesium transporter
FADFFPFK_01582 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
FADFFPFK_01583 1.2e-110 ykoI S Peptidase propeptide and YPEB domain
FADFFPFK_01584 2.4e-240 ykoH 2.7.13.3 T Histidine kinase
FADFFPFK_01585 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_01586 1.8e-110 ykoF S YKOF-related Family
FADFFPFK_01587 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
FADFFPFK_01588 5.7e-305 P ABC transporter, ATP-binding protein
FADFFPFK_01589 1.5e-135 ykoC P Cobalt transport protein
FADFFPFK_01590 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FADFFPFK_01591 1.5e-175 isp O Belongs to the peptidase S8 family
FADFFPFK_01592 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FADFFPFK_01593 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
FADFFPFK_01594 8.4e-72 ohrB O Organic hydroperoxide resistance protein
FADFFPFK_01595 4.4e-74 ohrR K COG1846 Transcriptional regulators
FADFFPFK_01596 4.8e-70 ohrA O Organic hydroperoxide resistance protein
FADFFPFK_01597 4.5e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FADFFPFK_01598 7.4e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FADFFPFK_01599 5.6e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
FADFFPFK_01600 9.1e-50 ykkD P Multidrug resistance protein
FADFFPFK_01601 1.1e-53 ykkC P Multidrug resistance protein
FADFFPFK_01602 3.6e-96 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FADFFPFK_01603 1.3e-96 ykkA S Protein of unknown function (DUF664)
FADFFPFK_01604 3.9e-128 ykjA S Protein of unknown function (DUF421)
FADFFPFK_01605 1.5e-09
FADFFPFK_01606 2.8e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FADFFPFK_01607 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
FADFFPFK_01608 9.4e-158 ykgA E Amidinotransferase
FADFFPFK_01609 1.4e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
FADFFPFK_01610 1.6e-185 ykfD E Belongs to the ABC transporter superfamily
FADFFPFK_01611 2.5e-169 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
FADFFPFK_01612 4.8e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
FADFFPFK_01613 7.6e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
FADFFPFK_01615 0.0 dppE E ABC transporter substrate-binding protein
FADFFPFK_01616 2.4e-189 dppD P Belongs to the ABC transporter superfamily
FADFFPFK_01617 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FADFFPFK_01618 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FADFFPFK_01619 5.1e-153 dppA E D-aminopeptidase
FADFFPFK_01620 9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
FADFFPFK_01621 9.8e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FADFFPFK_01622 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FADFFPFK_01623 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FADFFPFK_01625 6.1e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
FADFFPFK_01626 6.1e-241 steT E amino acid
FADFFPFK_01627 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
FADFFPFK_01628 5.8e-175 pit P phosphate transporter
FADFFPFK_01629 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
FADFFPFK_01630 6.7e-23 spoIISB S Stage II sporulation protein SB
FADFFPFK_01631 1.3e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FADFFPFK_01632 9.3e-40 xhlB S SPP1 phage holin
FADFFPFK_01633 2.8e-39 xhlA S Haemolysin XhlA
FADFFPFK_01634 2.8e-154 xepA
FADFFPFK_01635 2.1e-21 xkdX
FADFFPFK_01636 2.2e-43 xkdW S XkdW protein
FADFFPFK_01637 8e-178
FADFFPFK_01638 8.7e-41
FADFFPFK_01639 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
FADFFPFK_01640 3e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
FADFFPFK_01641 9.6e-71 xkdS S Protein of unknown function (DUF2634)
FADFFPFK_01642 2.1e-39 xkdR S Protein of unknown function (DUF2577)
FADFFPFK_01643 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
FADFFPFK_01644 2.7e-118 xkdP S Lysin motif
FADFFPFK_01645 1.8e-264 xkdO L Transglycosylase SLT domain
FADFFPFK_01646 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
FADFFPFK_01647 1e-75 xkdM S Phage tail tube protein
FADFFPFK_01648 2.5e-256 xkdK S Phage tail sheath C-terminal domain
FADFFPFK_01649 9.3e-77 xkdJ
FADFFPFK_01650 1.1e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
FADFFPFK_01651 7.3e-64 yqbH S Domain of unknown function (DUF3599)
FADFFPFK_01652 3.3e-62 yqbG S Protein of unknown function (DUF3199)
FADFFPFK_01653 1.7e-168 xkdG S Phage capsid family
FADFFPFK_01654 7.7e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
FADFFPFK_01655 4.6e-285 yqbA S portal protein
FADFFPFK_01656 1.4e-253 xtmB S phage terminase, large subunit
FADFFPFK_01657 5.3e-139 xtmA L phage terminase small subunit
FADFFPFK_01658 3.5e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
FADFFPFK_01659 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
FADFFPFK_01662 4.1e-118 xkdC L Bacterial dnaA protein
FADFFPFK_01663 5e-156 xkdB K sequence-specific DNA binding
FADFFPFK_01665 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
FADFFPFK_01666 2.3e-110 xkdA E IrrE N-terminal-like domain
FADFFPFK_01667 4.4e-160 ydbD P Catalase
FADFFPFK_01668 2.1e-111 yjqB S Pfam:DUF867
FADFFPFK_01669 4e-60 yjqA S Bacterial PH domain
FADFFPFK_01670 2.9e-168 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
FADFFPFK_01671 5.3e-40 S YCII-related domain
FADFFPFK_01673 1e-212 S response regulator aspartate phosphatase
FADFFPFK_01674 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
FADFFPFK_01675 8e-79 yjoA S DinB family
FADFFPFK_01676 7.4e-130 MA20_18170 S membrane transporter protein
FADFFPFK_01677 5.6e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
FADFFPFK_01678 1.3e-281 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
FADFFPFK_01679 1.5e-183 exuR K transcriptional
FADFFPFK_01680 4.1e-226 exuT G Sugar (and other) transporter
FADFFPFK_01681 1.7e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FADFFPFK_01682 1.2e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
FADFFPFK_01683 6.5e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
FADFFPFK_01684 9.3e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
FADFFPFK_01685 1.2e-247 yjmB G symporter YjmB
FADFFPFK_01686 7.9e-279 uxaC 5.3.1.12 G glucuronate isomerase
FADFFPFK_01687 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
FADFFPFK_01688 7.1e-66 yjlC S Protein of unknown function (DUF1641)
FADFFPFK_01689 9.8e-91 yjlB S Cupin domain
FADFFPFK_01690 2.8e-53 yjlA EG Putative multidrug resistance efflux transporter
FADFFPFK_01691 1.7e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
FADFFPFK_01692 9.5e-122 ybbM S transport system, permease component
FADFFPFK_01693 2.9e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
FADFFPFK_01694 8.2e-30
FADFFPFK_01695 7.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
FADFFPFK_01696 1.7e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
FADFFPFK_01698 2.5e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
FADFFPFK_01699 2e-10 S Domain of unknown function (DUF4352)
FADFFPFK_01700 1.5e-92 yjgD S Protein of unknown function (DUF1641)
FADFFPFK_01701 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
FADFFPFK_01702 4.4e-103 yjgB S Domain of unknown function (DUF4309)
FADFFPFK_01703 4.9e-34 T PhoQ Sensor
FADFFPFK_01704 1.1e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
FADFFPFK_01705 2.3e-20 yjfB S Putative motility protein
FADFFPFK_01706 5.1e-81 S Protein of unknown function (DUF2690)
FADFFPFK_01707 5.5e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
FADFFPFK_01709 1.2e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
FADFFPFK_01710 7.8e-52 yjdJ S Domain of unknown function (DUF4306)
FADFFPFK_01711 7.1e-29 S Domain of unknown function (DUF4177)
FADFFPFK_01712 2.2e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FADFFPFK_01714 5.3e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
FADFFPFK_01715 3e-45 yjdF S Protein of unknown function (DUF2992)
FADFFPFK_01716 1.4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
FADFFPFK_01717 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
FADFFPFK_01718 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
FADFFPFK_01719 2.3e-45 yjcN
FADFFPFK_01720 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
FADFFPFK_01721 4.1e-180 S response regulator aspartate phosphatase
FADFFPFK_01724 8.3e-21
FADFFPFK_01725 3e-249 M nucleic acid phosphodiester bond hydrolysis
FADFFPFK_01726 1.1e-30
FADFFPFK_01727 8.8e-18
FADFFPFK_01729 5.6e-209 yjcL S Protein of unknown function (DUF819)
FADFFPFK_01730 3.6e-38 rimJ 2.3.1.128 J Alanine acetyltransferase
FADFFPFK_01731 1.8e-33 rimJ 2.3.1.128 J Alanine acetyltransferase
FADFFPFK_01732 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FADFFPFK_01733 8e-213 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FADFFPFK_01734 8.5e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
FADFFPFK_01735 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
FADFFPFK_01736 1.5e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FADFFPFK_01737 1.7e-38
FADFFPFK_01738 0.0 yjcD 3.6.4.12 L DNA helicase
FADFFPFK_01739 4.9e-38 spoVIF S Stage VI sporulation protein F
FADFFPFK_01742 1.3e-55 yjcA S Protein of unknown function (DUF1360)
FADFFPFK_01743 5.2e-55 cotV S Spore Coat Protein X and V domain
FADFFPFK_01744 8.5e-32 cotW
FADFFPFK_01745 6.4e-77 cotX S Spore Coat Protein X and V domain
FADFFPFK_01746 3.4e-96 cotY S Spore coat protein Z
FADFFPFK_01747 5.2e-83 cotZ S Spore coat protein
FADFFPFK_01748 5.9e-54 yjbX S Spore coat protein
FADFFPFK_01749 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
FADFFPFK_01750 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
FADFFPFK_01751 6.2e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
FADFFPFK_01752 5.8e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
FADFFPFK_01753 6.7e-30 thiS H thiamine diphosphate biosynthetic process
FADFFPFK_01754 8.3e-215 thiO 1.4.3.19 E Glycine oxidase
FADFFPFK_01755 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
FADFFPFK_01756 2.2e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FADFFPFK_01757 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
FADFFPFK_01758 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
FADFFPFK_01759 2.6e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FADFFPFK_01760 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FADFFPFK_01761 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
FADFFPFK_01762 2.7e-61 yjbL S Belongs to the UPF0738 family
FADFFPFK_01763 9.2e-101 yjbK S protein conserved in bacteria
FADFFPFK_01764 3.9e-88 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
FADFFPFK_01765 3.7e-72 yjbI S Bacterial-like globin
FADFFPFK_01766 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
FADFFPFK_01768 1.8e-20
FADFFPFK_01769 0.0 pepF E oligoendopeptidase F
FADFFPFK_01770 4.4e-219 yjbF S Competence protein
FADFFPFK_01771 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
FADFFPFK_01772 6e-112 yjbE P Integral membrane protein TerC family
FADFFPFK_01773 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
FADFFPFK_01774 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FADFFPFK_01775 4.5e-203 yjbB EGP Major Facilitator Superfamily
FADFFPFK_01776 5.5e-172 oppF E Belongs to the ABC transporter superfamily
FADFFPFK_01777 3.4e-197 oppD P Belongs to the ABC transporter superfamily
FADFFPFK_01778 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FADFFPFK_01779 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FADFFPFK_01780 9.4e-308 oppA E ABC transporter substrate-binding protein
FADFFPFK_01781 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
FADFFPFK_01782 5e-147 yjbA S Belongs to the UPF0736 family
FADFFPFK_01783 2.3e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FADFFPFK_01784 2.2e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FADFFPFK_01785 4.1e-279 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
FADFFPFK_01786 4.2e-186 appF E Belongs to the ABC transporter superfamily
FADFFPFK_01787 8.8e-184 appD P Belongs to the ABC transporter superfamily
FADFFPFK_01788 1.2e-148 yjaZ O Zn-dependent protease
FADFFPFK_01789 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FADFFPFK_01790 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FADFFPFK_01791 3.9e-10 yjzB
FADFFPFK_01792 7.3e-26 comZ S ComZ
FADFFPFK_01793 2.5e-183 med S Transcriptional activator protein med
FADFFPFK_01794 6.9e-101 yjaV
FADFFPFK_01795 1.8e-141 yjaU I carboxylic ester hydrolase activity
FADFFPFK_01796 2.3e-16 yjzD S Protein of unknown function (DUF2929)
FADFFPFK_01797 9.5e-28 yjzC S YjzC-like protein
FADFFPFK_01798 2.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FADFFPFK_01799 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
FADFFPFK_01800 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FADFFPFK_01801 3.9e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
FADFFPFK_01802 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
FADFFPFK_01803 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FADFFPFK_01804 4.7e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FADFFPFK_01805 1.7e-88 norB G Major Facilitator Superfamily
FADFFPFK_01806 1.7e-268 yitY C D-arabinono-1,4-lactone oxidase
FADFFPFK_01807 1.5e-22 pilT S Proteolipid membrane potential modulator
FADFFPFK_01808 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
FADFFPFK_01809 1.7e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
FADFFPFK_01810 5.4e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
FADFFPFK_01812 1.2e-17 S Protein of unknown function (DUF3813)
FADFFPFK_01813 5e-73 ipi S Intracellular proteinase inhibitor
FADFFPFK_01814 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
FADFFPFK_01815 9.3e-158 yitS S protein conserved in bacteria
FADFFPFK_01816 3.9e-306 nprB 3.4.24.28 E Peptidase M4
FADFFPFK_01817 1.4e-44 yitR S Domain of unknown function (DUF3784)
FADFFPFK_01818 1.3e-94
FADFFPFK_01819 1.5e-58 K Transcriptional regulator PadR-like family
FADFFPFK_01820 1.5e-97 S Sporulation delaying protein SdpA
FADFFPFK_01821 9.8e-164
FADFFPFK_01822 8.5e-94
FADFFPFK_01823 3.4e-160 cvfB S protein conserved in bacteria
FADFFPFK_01824 8.6e-55 yajQ S Belongs to the UPF0234 family
FADFFPFK_01825 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
FADFFPFK_01826 9.2e-72 yjcF S Acetyltransferase (GNAT) domain
FADFFPFK_01827 7.9e-157 yitH K Acetyltransferase (GNAT) domain
FADFFPFK_01828 1.3e-227 yitG EGP Major facilitator Superfamily
FADFFPFK_01829 3.5e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
FADFFPFK_01830 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FADFFPFK_01831 3.5e-140 yitD 4.4.1.19 S synthase
FADFFPFK_01832 1.2e-118 comB 3.1.3.71 H Belongs to the ComB family
FADFFPFK_01833 1.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
FADFFPFK_01834 3.3e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
FADFFPFK_01835 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
FADFFPFK_01836 1e-153 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FADFFPFK_01837 1.2e-35 mcbG S Pentapeptide repeats (9 copies)
FADFFPFK_01838 5.6e-272 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FADFFPFK_01839 6e-106 argO S Lysine exporter protein LysE YggA
FADFFPFK_01840 5.3e-92 yisT S DinB family
FADFFPFK_01841 2.3e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
FADFFPFK_01842 2e-183 purR K helix_turn _helix lactose operon repressor
FADFFPFK_01843 3.5e-160 yisR K Transcriptional regulator
FADFFPFK_01844 4e-243 yisQ V Mate efflux family protein
FADFFPFK_01845 2.1e-114 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
FADFFPFK_01846 0.0 asnO 6.3.5.4 E Asparagine synthase
FADFFPFK_01847 1.8e-101 yisN S Protein of unknown function (DUF2777)
FADFFPFK_01848 0.0 wprA O Belongs to the peptidase S8 family
FADFFPFK_01849 3.9e-57 yisL S UPF0344 protein
FADFFPFK_01850 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
FADFFPFK_01851 1.1e-172 cotH M Spore Coat
FADFFPFK_01852 1.5e-22 yisI S Spo0E like sporulation regulatory protein
FADFFPFK_01853 1.9e-33 gerPA S Spore germination protein
FADFFPFK_01854 4e-34 gerPB S cell differentiation
FADFFPFK_01855 5.3e-54 gerPC S Spore germination protein
FADFFPFK_01856 1.1e-23 gerPD S Spore germination protein
FADFFPFK_01857 5.3e-63 gerPE S Spore germination protein GerPE
FADFFPFK_01858 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
FADFFPFK_01859 2.5e-49 yisB V COG1403 Restriction endonuclease
FADFFPFK_01860 0.0 sbcC L COG0419 ATPase involved in DNA repair
FADFFPFK_01861 4.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
FADFFPFK_01862 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
FADFFPFK_01863 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
FADFFPFK_01864 6.4e-78 yhjR S Rubrerythrin
FADFFPFK_01865 1.7e-229 S Sugar transport-related sRNA regulator N-term
FADFFPFK_01866 3.9e-87 S Sugar transport-related sRNA regulator N-term
FADFFPFK_01867 4.9e-213 EGP Transmembrane secretion effector
FADFFPFK_01868 4.2e-201 abrB S membrane
FADFFPFK_01869 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
FADFFPFK_01870 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
FADFFPFK_01871 2.9e-159 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
FADFFPFK_01872 7.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
FADFFPFK_01873 1.1e-212 glcP G Major Facilitator Superfamily
FADFFPFK_01874 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
FADFFPFK_01875 2e-280 yhjG CH FAD binding domain
FADFFPFK_01876 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
FADFFPFK_01877 9.1e-110 yhjE S SNARE associated Golgi protein
FADFFPFK_01878 2.5e-59 yhjD
FADFFPFK_01879 6.9e-27 yhjC S Protein of unknown function (DUF3311)
FADFFPFK_01880 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FADFFPFK_01881 3.9e-41 yhjA S Excalibur calcium-binding domain
FADFFPFK_01882 1.4e-167 IQ Enoyl-(Acyl carrier protein) reductase
FADFFPFK_01883 4.2e-109 comK K Competence transcription factor
FADFFPFK_01884 1.3e-32 yhzC S IDEAL
FADFFPFK_01885 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FADFFPFK_01886 8e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
FADFFPFK_01887 3.1e-181 hemAT NT chemotaxis protein
FADFFPFK_01888 1.9e-90 bioY S BioY family
FADFFPFK_01889 1.9e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
FADFFPFK_01890 3.2e-195 vraB 2.3.1.9 I Belongs to the thiolase family
FADFFPFK_01891 5.5e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
FADFFPFK_01892 4.3e-159 yfmC M Periplasmic binding protein
FADFFPFK_01893 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
FADFFPFK_01894 1.6e-76 VY92_01935 K acetyltransferase
FADFFPFK_01895 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
FADFFPFK_01896 1.2e-241 yhfN 3.4.24.84 O Peptidase M48
FADFFPFK_01897 1.3e-64 yhfM
FADFFPFK_01898 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
FADFFPFK_01899 1.9e-110 yhfK GM NmrA-like family
FADFFPFK_01900 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
FADFFPFK_01901 5.2e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
FADFFPFK_01902 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FADFFPFK_01903 1.1e-71 3.4.13.21 S ASCH
FADFFPFK_01904 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
FADFFPFK_01905 2.2e-137 yhfC S Putative membrane peptidase family (DUF2324)
FADFFPFK_01906 8.7e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FADFFPFK_01907 1.7e-214 yhgE S YhgE Pip N-terminal domain protein
FADFFPFK_01908 4.6e-100 yhgD K Transcriptional regulator
FADFFPFK_01909 5e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FADFFPFK_01910 5.2e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
FADFFPFK_01911 2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FADFFPFK_01912 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
FADFFPFK_01913 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
FADFFPFK_01914 9.7e-29 1.15.1.2 C Rubrerythrin
FADFFPFK_01915 4.8e-244 yhfA C membrane
FADFFPFK_01916 1.2e-227 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
FADFFPFK_01917 6.9e-114 ecsC S EcsC protein family
FADFFPFK_01918 1.6e-214 ecsB U ABC transporter
FADFFPFK_01919 1.8e-136 ecsA V transporter (ATP-binding protein)
FADFFPFK_01920 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
FADFFPFK_01921 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FADFFPFK_01922 3.6e-80 trpP S Tryptophan transporter TrpP
FADFFPFK_01923 2.4e-21
FADFFPFK_01924 7e-39 yhaH S YtxH-like protein
FADFFPFK_01925 1e-113 hpr K Negative regulator of protease production and sporulation
FADFFPFK_01926 1.3e-54 yhaI S Protein of unknown function (DUF1878)
FADFFPFK_01927 1.1e-89 yhaK S Putative zincin peptidase
FADFFPFK_01928 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
FADFFPFK_01929 1.6e-21 yhaL S Sporulation protein YhaL
FADFFPFK_01930 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
FADFFPFK_01931 0.0 yhaN L AAA domain
FADFFPFK_01932 2.6e-225 yhaO L DNA repair exonuclease
FADFFPFK_01933 9.4e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
FADFFPFK_01934 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
FADFFPFK_01935 7e-26 S YhzD-like protein
FADFFPFK_01936 2.7e-130 yhaR 5.3.3.18 I enoyl-CoA hydratase
FADFFPFK_01938 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
FADFFPFK_01939 1.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
FADFFPFK_01940 2.5e-291 hemZ H coproporphyrinogen III oxidase
FADFFPFK_01941 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
FADFFPFK_01942 8.8e-170 yhaZ L DNA alkylation repair enzyme
FADFFPFK_01943 9.5e-48 yheA S Belongs to the UPF0342 family
FADFFPFK_01944 2.2e-202 yheB S Belongs to the UPF0754 family
FADFFPFK_01945 4.3e-216 yheC HJ YheC/D like ATP-grasp
FADFFPFK_01946 9.7e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
FADFFPFK_01947 1.3e-36 yheE S Family of unknown function (DUF5342)
FADFFPFK_01948 3.1e-27 sspB S spore protein
FADFFPFK_01949 1.2e-109 yheG GM NAD(P)H-binding
FADFFPFK_01950 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
FADFFPFK_01951 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
FADFFPFK_01952 3.8e-83 nhaX T Belongs to the universal stress protein A family
FADFFPFK_01953 3.3e-229 nhaC C Na H antiporter
FADFFPFK_01954 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
FADFFPFK_01955 2.1e-146 yheN G deacetylase
FADFFPFK_01956 4.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
FADFFPFK_01957 5.6e-203 yhdY M Mechanosensitive ion channel
FADFFPFK_01959 1.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FADFFPFK_01960 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FADFFPFK_01961 1.7e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FADFFPFK_01962 7.3e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
FADFFPFK_01963 1.7e-221 yhdR 2.6.1.1 E Aminotransferase
FADFFPFK_01964 4.7e-74 cueR K transcriptional
FADFFPFK_01965 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
FADFFPFK_01966 6.7e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
FADFFPFK_01967 4.4e-191 yhdN C Aldo keto reductase
FADFFPFK_01968 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
FADFFPFK_01969 6.6e-201 yhdL S Sigma factor regulator N-terminal
FADFFPFK_01970 8.1e-45 yhdK S Sigma-M inhibitor protein
FADFFPFK_01971 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FADFFPFK_01972 5.1e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FADFFPFK_01973 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
FADFFPFK_01974 3.4e-250 yhdG E amino acid
FADFFPFK_01975 4.6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FADFFPFK_01976 1.7e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
FADFFPFK_01977 1.9e-161 citR K Transcriptional regulator
FADFFPFK_01978 1.2e-140 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
FADFFPFK_01979 9.2e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
FADFFPFK_01980 2.1e-276 ycgB S Stage V sporulation protein R
FADFFPFK_01981 6.9e-236 ygxB M Conserved TM helix
FADFFPFK_01982 5.1e-75 nsrR K Transcriptional regulator
FADFFPFK_01983 1.9e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
FADFFPFK_01984 2e-52 yhdC S Protein of unknown function (DUF3889)
FADFFPFK_01985 1.2e-38 yhdB S YhdB-like protein
FADFFPFK_01986 2.7e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
FADFFPFK_01987 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FADFFPFK_01988 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
FADFFPFK_01989 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
FADFFPFK_01990 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FADFFPFK_01991 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FADFFPFK_01992 5.7e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
FADFFPFK_01993 9.9e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FADFFPFK_01994 6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FADFFPFK_01995 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
FADFFPFK_01996 1e-119 yhcW 5.4.2.6 S hydrolase
FADFFPFK_01997 9.9e-68 yhcV S COG0517 FOG CBS domain
FADFFPFK_01998 9.3e-68 yhcU S Family of unknown function (DUF5365)
FADFFPFK_01999 2.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FADFFPFK_02000 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
FADFFPFK_02001 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
FADFFPFK_02002 5.2e-100 yhcQ M Spore coat protein
FADFFPFK_02003 2.5e-167 yhcP
FADFFPFK_02004 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FADFFPFK_02005 1.1e-40 yhcM
FADFFPFK_02006 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FADFFPFK_02007 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
FADFFPFK_02008 8.3e-151 metQ M Belongs to the nlpA lipoprotein family
FADFFPFK_02009 1e-30 cspB K Cold-shock protein
FADFFPFK_02010 8.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FADFFPFK_02011 7.7e-166 yhcH V ABC transporter, ATP-binding protein
FADFFPFK_02012 4e-122 yhcG V ABC transporter, ATP-binding protein
FADFFPFK_02013 1.9e-59 yhcF K Transcriptional regulator
FADFFPFK_02014 3e-54
FADFFPFK_02015 2.8e-37 yhcC
FADFFPFK_02016 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
FADFFPFK_02017 3.1e-271 yhcA EGP Major facilitator Superfamily
FADFFPFK_02018 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
FADFFPFK_02019 2.2e-76 yhbI K DNA-binding transcription factor activity
FADFFPFK_02020 2.5e-225 yhbH S Belongs to the UPF0229 family
FADFFPFK_02021 0.0 prkA T Ser protein kinase
FADFFPFK_02022 3e-69 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
FADFFPFK_02023 1.1e-58 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
FADFFPFK_02024 7.9e-109 yhbD K Protein of unknown function (DUF4004)
FADFFPFK_02025 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FADFFPFK_02026 1.1e-175 yhbB S Putative amidase domain
FADFFPFK_02027 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FADFFPFK_02028 1.1e-112 yhzB S B3/4 domain
FADFFPFK_02030 4.4e-29 K Transcriptional regulator
FADFFPFK_02031 1.7e-76 ygaO
FADFFPFK_02032 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FADFFPFK_02034 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
FADFFPFK_02035 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
FADFFPFK_02036 8.1e-169 ssuA M Sulfonate ABC transporter
FADFFPFK_02037 1.5e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
FADFFPFK_02038 5.6e-288 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
FADFFPFK_02040 3.4e-263 ygaK C Berberine and berberine like
FADFFPFK_02041 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FADFFPFK_02043 4.2e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
FADFFPFK_02044 1.2e-26
FADFFPFK_02045 6.5e-142 spo0M S COG4326 Sporulation control protein
FADFFPFK_02049 2e-08
FADFFPFK_02057 7.8e-08
FADFFPFK_02062 8e-91 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FADFFPFK_02063 5.7e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
FADFFPFK_02064 8.4e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
FADFFPFK_02065 2.3e-246 yoeA V MATE efflux family protein
FADFFPFK_02066 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
FADFFPFK_02068 6.5e-96 L Integrase
FADFFPFK_02069 1.1e-33 yoeD G Helix-turn-helix domain
FADFFPFK_02070 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
FADFFPFK_02071 4.8e-154 gltR1 K Transcriptional regulator
FADFFPFK_02072 6.7e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
FADFFPFK_02073 5.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
FADFFPFK_02074 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
FADFFPFK_02075 7.8e-155 gltC K Transcriptional regulator
FADFFPFK_02076 6e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FADFFPFK_02077 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FADFFPFK_02078 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
FADFFPFK_02079 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
FADFFPFK_02080 1.3e-08 yoxC S Bacterial protein of unknown function (DUF948)
FADFFPFK_02081 3.5e-135 yoxB
FADFFPFK_02082 2.4e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FADFFPFK_02083 4.9e-126 V ABC-2 family transporter protein
FADFFPFK_02084 5.8e-95 V ABC-2 family transporter protein
FADFFPFK_02085 9.7e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
FADFFPFK_02086 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
FADFFPFK_02087 1.2e-233 yoaB EGP Major facilitator Superfamily
FADFFPFK_02088 1.2e-274 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
FADFFPFK_02089 1.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FADFFPFK_02090 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FADFFPFK_02091 3.2e-33 yoaF
FADFFPFK_02092 5e-08 ywlA S Uncharacterised protein family (UPF0715)
FADFFPFK_02093 2.6e-13
FADFFPFK_02094 8.2e-37 S Protein of unknown function (DUF4025)
FADFFPFK_02095 2.4e-181 mcpU NT methyl-accepting chemotaxis protein
FADFFPFK_02096 1.5e-277 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
FADFFPFK_02097 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
FADFFPFK_02098 2.9e-109 yoaK S Membrane
FADFFPFK_02099 8.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
FADFFPFK_02100 3.3e-129 yoqW S Belongs to the SOS response-associated peptidase family
FADFFPFK_02103 4.6e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
FADFFPFK_02106 5e-87
FADFFPFK_02107 7.1e-172 yoaR V vancomycin resistance protein
FADFFPFK_02108 3.6e-74 yoaS S Protein of unknown function (DUF2975)
FADFFPFK_02109 4.4e-30 yozG K Transcriptional regulator
FADFFPFK_02110 3.7e-148 yoaT S Protein of unknown function (DUF817)
FADFFPFK_02111 8.6e-159 yoaU K LysR substrate binding domain
FADFFPFK_02112 1.1e-156 yijE EG EamA-like transporter family
FADFFPFK_02113 5.9e-76 yoaW
FADFFPFK_02114 3.5e-166 bla 3.5.2.6 V beta-lactamase
FADFFPFK_02117 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
FADFFPFK_02118 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
FADFFPFK_02119 1.7e-12 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
FADFFPFK_02125 2.5e-116
FADFFPFK_02127 2.2e-63 yoaQ S Evidence 4 Homologs of previously reported genes of
FADFFPFK_02129 1.9e-35 S aspartate phosphatase
FADFFPFK_02130 2.1e-58 S response regulator aspartate phosphatase
FADFFPFK_02132 6.9e-19
FADFFPFK_02133 2.8e-33 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FADFFPFK_02134 2e-17 UW nuclease activity
FADFFPFK_02135 8.7e-65 yokH G SMI1 / KNR4 family
FADFFPFK_02136 5.5e-16 yokH G SMI1 / KNR4 family
FADFFPFK_02137 2.9e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
FADFFPFK_02138 3.5e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
FADFFPFK_02139 6.1e-134 yobQ K helix_turn_helix, arabinose operon control protein
FADFFPFK_02140 3.1e-141 yobR 2.3.1.1 J FR47-like protein
FADFFPFK_02141 6.9e-96 yobS K Transcriptional regulator
FADFFPFK_02142 7.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
FADFFPFK_02143 1.6e-82 yobU K Bacterial transcription activator, effector binding domain
FADFFPFK_02144 6e-174 yobV K WYL domain
FADFFPFK_02145 1.8e-90 yobW
FADFFPFK_02146 1e-51 czrA K transcriptional
FADFFPFK_02147 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
FADFFPFK_02148 1.5e-92 yozB S membrane
FADFFPFK_02149 3.2e-144
FADFFPFK_02150 1.5e-91 yocC
FADFFPFK_02151 7.1e-186 yocD 3.4.17.13 V peptidase S66
FADFFPFK_02152 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
FADFFPFK_02153 7.1e-198 desK 2.7.13.3 T Histidine kinase
FADFFPFK_02154 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FADFFPFK_02155 9.3e-113 yocH CBM50 M COG1388 FOG LysM repeat
FADFFPFK_02156 0.0 recQ 3.6.4.12 L DNA helicase
FADFFPFK_02157 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FADFFPFK_02158 3.3e-83 dksA T general stress protein
FADFFPFK_02159 5.4e-53 yocL
FADFFPFK_02160 1.4e-31
FADFFPFK_02161 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
FADFFPFK_02162 1.1e-40 yozN
FADFFPFK_02163 1.9e-36 yocN
FADFFPFK_02164 4.2e-56 yozO S Bacterial PH domain
FADFFPFK_02165 2.7e-31 yozC
FADFFPFK_02166 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
FADFFPFK_02167 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
FADFFPFK_02168 1.1e-163 sodA 1.15.1.1 P Superoxide dismutase
FADFFPFK_02169 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
FADFFPFK_02170 1.1e-167 yocS S -transporter
FADFFPFK_02171 9.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
FADFFPFK_02172 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
FADFFPFK_02173 0.0 yojO P Von Willebrand factor
FADFFPFK_02174 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
FADFFPFK_02175 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FADFFPFK_02176 1.8e-197 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
FADFFPFK_02177 9e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
FADFFPFK_02178 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FADFFPFK_02180 2.7e-244 norM V Multidrug efflux pump
FADFFPFK_02181 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FADFFPFK_02182 2.1e-125 yojG S deacetylase
FADFFPFK_02183 2.2e-60 yojF S Protein of unknown function (DUF1806)
FADFFPFK_02184 1.5e-43
FADFFPFK_02185 6.6e-162 rarD S -transporter
FADFFPFK_02186 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
FADFFPFK_02187 2e-09
FADFFPFK_02188 2.5e-205 gntP EG COG2610 H gluconate symporter and related permeases
FADFFPFK_02189 2.3e-63 yodA S tautomerase
FADFFPFK_02190 4.4e-55 yodB K transcriptional
FADFFPFK_02191 1.4e-107 yodC C nitroreductase
FADFFPFK_02192 2.1e-111 mhqD S Carboxylesterase
FADFFPFK_02193 9.3e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
FADFFPFK_02194 6.2e-28 S Protein of unknown function (DUF3311)
FADFFPFK_02195 7.8e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FADFFPFK_02196 8.2e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
FADFFPFK_02197 6.3e-128 yodH Q Methyltransferase
FADFFPFK_02198 1.5e-23 yodI
FADFFPFK_02199 1.6e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
FADFFPFK_02200 9.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
FADFFPFK_02201 5.3e-09
FADFFPFK_02202 3.6e-54 yodL S YodL-like
FADFFPFK_02203 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
FADFFPFK_02204 2.8e-24 yozD S YozD-like protein
FADFFPFK_02206 6e-123 yodN
FADFFPFK_02207 1.4e-36 yozE S Belongs to the UPF0346 family
FADFFPFK_02208 5.4e-46 yokU S YokU-like protein, putative antitoxin
FADFFPFK_02209 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
FADFFPFK_02210 2.3e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
FADFFPFK_02211 1.8e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
FADFFPFK_02212 3.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
FADFFPFK_02213 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FADFFPFK_02214 2.2e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FADFFPFK_02216 1.8e-144 yiiD K acetyltransferase
FADFFPFK_02217 4.2e-255 cgeD M maturation of the outermost layer of the spore
FADFFPFK_02218 1.2e-65 cgeA
FADFFPFK_02219 6.3e-187 cgeB S Spore maturation protein
FADFFPFK_02220 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
FADFFPFK_02221 4.3e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
FADFFPFK_02222 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
FADFFPFK_02223 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FADFFPFK_02224 1.6e-70 ypoP K transcriptional
FADFFPFK_02225 1.7e-222 mepA V MATE efflux family protein
FADFFPFK_02226 1.2e-28 ypmT S Uncharacterized ympT
FADFFPFK_02227 1.1e-98 ypmS S protein conserved in bacteria
FADFFPFK_02228 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
FADFFPFK_02229 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
FADFFPFK_02230 8.9e-40 ypmP S Protein of unknown function (DUF2535)
FADFFPFK_02231 2e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FADFFPFK_02232 6.1e-185 pspF K Transcriptional regulator
FADFFPFK_02233 4.2e-110 hlyIII S protein, Hemolysin III
FADFFPFK_02234 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
FADFFPFK_02235 1.5e-94 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FADFFPFK_02236 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FADFFPFK_02237 1.2e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
FADFFPFK_02238 2.5e-112 ypjP S YpjP-like protein
FADFFPFK_02239 1.7e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
FADFFPFK_02240 1.9e-74 yphP S Belongs to the UPF0403 family
FADFFPFK_02241 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
FADFFPFK_02242 1.5e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
FADFFPFK_02243 1.2e-106 ypgQ S phosphohydrolase
FADFFPFK_02244 6.8e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
FADFFPFK_02245 2.4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FADFFPFK_02247 1e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
FADFFPFK_02248 7.9e-31 cspD K Cold-shock protein
FADFFPFK_02249 3.8e-16 degR
FADFFPFK_02250 1.8e-30 S Protein of unknown function (DUF2564)
FADFFPFK_02251 2.5e-28 ypeQ S Zinc-finger
FADFFPFK_02252 4.7e-135 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
FADFFPFK_02253 1e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FADFFPFK_02254 2.1e-67 rnhA 3.1.26.4 L Ribonuclease
FADFFPFK_02256 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
FADFFPFK_02257 2e-07
FADFFPFK_02258 1e-38 ypbS S Protein of unknown function (DUF2533)
FADFFPFK_02259 0.0 ypbR S Dynamin family
FADFFPFK_02261 5.1e-87 ypbQ S protein conserved in bacteria
FADFFPFK_02262 3.5e-205 bcsA Q Naringenin-chalcone synthase
FADFFPFK_02263 9.5e-226 pbuX F xanthine
FADFFPFK_02264 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
FADFFPFK_02265 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FADFFPFK_02266 6.6e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
FADFFPFK_02267 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
FADFFPFK_02268 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
FADFFPFK_02269 2.2e-185 ptxS K transcriptional
FADFFPFK_02270 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FADFFPFK_02271 2.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FADFFPFK_02272 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
FADFFPFK_02274 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
FADFFPFK_02275 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
FADFFPFK_02276 2.8e-91 ypsA S Belongs to the UPF0398 family
FADFFPFK_02277 9.5e-236 yprB L RNase_H superfamily
FADFFPFK_02278 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
FADFFPFK_02279 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
FADFFPFK_02280 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
FADFFPFK_02281 1e-47 yppG S YppG-like protein
FADFFPFK_02283 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
FADFFPFK_02286 2.8e-187 yppC S Protein of unknown function (DUF2515)
FADFFPFK_02287 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FADFFPFK_02288 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
FADFFPFK_02289 4.7e-93 ypoC
FADFFPFK_02290 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FADFFPFK_02291 5.7e-129 dnaD L DNA replication protein DnaD
FADFFPFK_02292 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
FADFFPFK_02293 6.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
FADFFPFK_02294 2.2e-79 ypmB S protein conserved in bacteria
FADFFPFK_02295 6.7e-23 ypmA S Protein of unknown function (DUF4264)
FADFFPFK_02296 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
FADFFPFK_02297 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FADFFPFK_02298 1.4e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FADFFPFK_02299 5.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
FADFFPFK_02300 3.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FADFFPFK_02301 4.6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FADFFPFK_02302 7.7e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
FADFFPFK_02303 4.9e-128 bshB1 S proteins, LmbE homologs
FADFFPFK_02304 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
FADFFPFK_02305 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
FADFFPFK_02306 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
FADFFPFK_02307 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
FADFFPFK_02308 1.5e-141 ypjB S sporulation protein
FADFFPFK_02309 3.1e-99 ypjA S membrane
FADFFPFK_02310 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
FADFFPFK_02311 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
FADFFPFK_02312 1.1e-96 qcrA C Menaquinol-cytochrome c reductase
FADFFPFK_02313 1.2e-76 ypiF S Protein of unknown function (DUF2487)
FADFFPFK_02314 1.1e-98 ypiB S Belongs to the UPF0302 family
FADFFPFK_02315 2.9e-232 S COG0457 FOG TPR repeat
FADFFPFK_02316 1.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
FADFFPFK_02317 1.1e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
FADFFPFK_02318 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FADFFPFK_02319 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
FADFFPFK_02320 4.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FADFFPFK_02321 5.1e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
FADFFPFK_02322 4.3e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
FADFFPFK_02323 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FADFFPFK_02324 2.1e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FADFFPFK_02325 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
FADFFPFK_02326 1.7e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FADFFPFK_02327 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FADFFPFK_02328 4.2e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
FADFFPFK_02329 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
FADFFPFK_02330 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FADFFPFK_02331 7.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
FADFFPFK_02332 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
FADFFPFK_02333 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
FADFFPFK_02334 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
FADFFPFK_02335 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FADFFPFK_02336 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FADFFPFK_02337 6e-137 yphF
FADFFPFK_02338 1.2e-18 yphE S Protein of unknown function (DUF2768)
FADFFPFK_02339 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
FADFFPFK_02340 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
FADFFPFK_02341 2.1e-28 ypzH
FADFFPFK_02342 3.3e-161 seaA S YIEGIA protein
FADFFPFK_02343 3.9e-102 yphA
FADFFPFK_02344 1e-07 S YpzI-like protein
FADFFPFK_02345 3.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
FADFFPFK_02346 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
FADFFPFK_02347 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
FADFFPFK_02348 1.8e-23 S Family of unknown function (DUF5359)
FADFFPFK_02349 3.9e-111 ypfA M Flagellar protein YcgR
FADFFPFK_02350 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
FADFFPFK_02351 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
FADFFPFK_02352 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
FADFFPFK_02353 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
FADFFPFK_02354 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
FADFFPFK_02355 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
FADFFPFK_02356 2.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
FADFFPFK_02357 2.8e-81 ypbF S Protein of unknown function (DUF2663)
FADFFPFK_02358 1.7e-78 ypbE M Lysin motif
FADFFPFK_02359 1.1e-99 ypbD S metal-dependent membrane protease
FADFFPFK_02360 1.2e-285 recQ 3.6.4.12 L DNA helicase
FADFFPFK_02361 2.7e-199 ypbB 5.1.3.1 S protein conserved in bacteria
FADFFPFK_02362 4.7e-41 fer C Ferredoxin
FADFFPFK_02363 1e-83 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FADFFPFK_02364 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FADFFPFK_02365 2.7e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
FADFFPFK_02366 3.1e-190 rsiX
FADFFPFK_02367 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
FADFFPFK_02368 0.0 resE 2.7.13.3 T Histidine kinase
FADFFPFK_02369 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_02370 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
FADFFPFK_02371 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
FADFFPFK_02372 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
FADFFPFK_02373 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FADFFPFK_02374 1.9e-87 spmB S Spore maturation protein
FADFFPFK_02375 3.5e-103 spmA S Spore maturation protein
FADFFPFK_02376 3e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
FADFFPFK_02377 7.6e-97 ypuI S Protein of unknown function (DUF3907)
FADFFPFK_02378 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FADFFPFK_02379 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FADFFPFK_02380 1.2e-91 ypuF S Domain of unknown function (DUF309)
FADFFPFK_02381 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FADFFPFK_02382 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
FADFFPFK_02383 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FADFFPFK_02384 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
FADFFPFK_02385 7.1e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FADFFPFK_02386 7.8e-55 ypuD
FADFFPFK_02387 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
FADFFPFK_02388 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
FADFFPFK_02389 3.4e-13 S PAP2 superfamily
FADFFPFK_02391 1.2e-07 eaeH M Domain of Unknown Function (DUF1259)
FADFFPFK_02393 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FADFFPFK_02394 3.6e-149 ypuA S Secreted protein
FADFFPFK_02395 3.4e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
FADFFPFK_02396 1.4e-273 spoVAF EG Stage V sporulation protein AF
FADFFPFK_02397 1.4e-110 spoVAEA S stage V sporulation protein
FADFFPFK_02398 2.2e-57 spoVAEB S stage V sporulation protein
FADFFPFK_02399 9e-192 spoVAD I Stage V sporulation protein AD
FADFFPFK_02400 2.3e-78 spoVAC S stage V sporulation protein AC
FADFFPFK_02401 1e-67 spoVAB S Stage V sporulation protein AB
FADFFPFK_02402 9.6e-112 spoVAA S Stage V sporulation protein AA
FADFFPFK_02403 9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FADFFPFK_02404 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
FADFFPFK_02405 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
FADFFPFK_02406 1.3e-210 dacF 3.4.16.4 M Belongs to the peptidase S11 family
FADFFPFK_02407 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FADFFPFK_02408 3.3e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
FADFFPFK_02409 2.6e-166 xerD L recombinase XerD
FADFFPFK_02410 3.7e-37 S Protein of unknown function (DUF4227)
FADFFPFK_02411 2.4e-80 fur P Belongs to the Fur family
FADFFPFK_02412 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
FADFFPFK_02413 5.5e-30 yqkK
FADFFPFK_02414 8e-241 mleA 1.1.1.38 C malic enzyme
FADFFPFK_02415 9.1e-235 mleN C Na H antiporter
FADFFPFK_02416 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
FADFFPFK_02417 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
FADFFPFK_02418 4.5e-58 ansR K Transcriptional regulator
FADFFPFK_02419 9e-220 yqxK 3.6.4.12 L DNA helicase
FADFFPFK_02420 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
FADFFPFK_02422 1.8e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
FADFFPFK_02423 3.1e-12 yqkE S Protein of unknown function (DUF3886)
FADFFPFK_02424 2.5e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
FADFFPFK_02425 9.4e-39 yqkC S Protein of unknown function (DUF2552)
FADFFPFK_02426 2.8e-54 yqkB S Belongs to the HesB IscA family
FADFFPFK_02427 1.1e-192 yqkA K GrpB protein
FADFFPFK_02428 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
FADFFPFK_02429 2e-85 yqjY K acetyltransferase
FADFFPFK_02430 1.7e-49 S YolD-like protein
FADFFPFK_02431 1.7e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FADFFPFK_02433 3.7e-224 yqjV G Major Facilitator Superfamily
FADFFPFK_02435 2.1e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FADFFPFK_02436 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
FADFFPFK_02437 7.1e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
FADFFPFK_02438 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
FADFFPFK_02439 2.2e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
FADFFPFK_02440 1.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FADFFPFK_02441 0.0 rocB E arginine degradation protein
FADFFPFK_02442 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
FADFFPFK_02443 1.7e-142 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FADFFPFK_02444 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FADFFPFK_02445 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
FADFFPFK_02446 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FADFFPFK_02447 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FADFFPFK_02448 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FADFFPFK_02449 4.5e-24 yqzJ
FADFFPFK_02450 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FADFFPFK_02451 1.3e-139 yqjF S Uncharacterized conserved protein (COG2071)
FADFFPFK_02452 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
FADFFPFK_02453 1.8e-289 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
FADFFPFK_02454 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
FADFFPFK_02456 1.4e-98 yqjB S protein conserved in bacteria
FADFFPFK_02457 3.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
FADFFPFK_02458 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FADFFPFK_02459 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
FADFFPFK_02460 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
FADFFPFK_02461 9.3e-77 yqiW S Belongs to the UPF0403 family
FADFFPFK_02462 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
FADFFPFK_02463 1.4e-207 norA EGP Major facilitator Superfamily
FADFFPFK_02464 2.6e-152 bmrR K helix_turn_helix, mercury resistance
FADFFPFK_02465 7.5e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FADFFPFK_02466 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FADFFPFK_02467 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FADFFPFK_02468 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FADFFPFK_02469 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
FADFFPFK_02470 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
FADFFPFK_02471 5.1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
FADFFPFK_02472 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
FADFFPFK_02473 4e-34 yqzF S Protein of unknown function (DUF2627)
FADFFPFK_02474 1.5e-161 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FADFFPFK_02475 1.8e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
FADFFPFK_02476 3.5e-205 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
FADFFPFK_02477 4.8e-210 mmgC I acyl-CoA dehydrogenase
FADFFPFK_02478 2.2e-154 hbdA 1.1.1.157 I Dehydrogenase
FADFFPFK_02479 1.3e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
FADFFPFK_02480 1.1e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FADFFPFK_02481 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
FADFFPFK_02482 6e-27
FADFFPFK_02483 2.3e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
FADFFPFK_02485 1.2e-143 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
FADFFPFK_02486 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
FADFFPFK_02487 1.9e-306 recN L May be involved in recombinational repair of damaged DNA
FADFFPFK_02488 1.7e-78 argR K Regulates arginine biosynthesis genes
FADFFPFK_02489 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
FADFFPFK_02490 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FADFFPFK_02491 6.5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FADFFPFK_02492 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FADFFPFK_02493 8.4e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FADFFPFK_02494 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FADFFPFK_02495 7.4e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FADFFPFK_02496 1.8e-66 yqhY S protein conserved in bacteria
FADFFPFK_02497 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
FADFFPFK_02498 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FADFFPFK_02499 1.6e-85 spoIIIAH S SpoIIIAH-like protein
FADFFPFK_02500 6.9e-103 spoIIIAG S stage III sporulation protein AG
FADFFPFK_02501 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
FADFFPFK_02502 8.4e-197 spoIIIAE S stage III sporulation protein AE
FADFFPFK_02503 2.3e-58 spoIIIAD S Stage III sporulation protein AD
FADFFPFK_02504 7.6e-29 spoIIIAC S stage III sporulation protein AC
FADFFPFK_02505 3.2e-84 spoIIIAB S Stage III sporulation protein
FADFFPFK_02506 1e-170 spoIIIAA S stage III sporulation protein AA
FADFFPFK_02507 7.9e-37 yqhV S Protein of unknown function (DUF2619)
FADFFPFK_02508 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FADFFPFK_02509 1.7e-172 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
FADFFPFK_02510 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
FADFFPFK_02511 6.6e-93 yqhR S Conserved membrane protein YqhR
FADFFPFK_02512 3.4e-172 yqhQ S Protein of unknown function (DUF1385)
FADFFPFK_02513 2.2e-61 yqhP
FADFFPFK_02514 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
FADFFPFK_02515 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
FADFFPFK_02516 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
FADFFPFK_02517 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
FADFFPFK_02518 4.1e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FADFFPFK_02519 6.4e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FADFFPFK_02520 2.4e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
FADFFPFK_02521 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
FADFFPFK_02522 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
FADFFPFK_02523 1.2e-24 sinI S Anti-repressor SinI
FADFFPFK_02524 1e-54 sinR K transcriptional
FADFFPFK_02525 1.9e-141 tasA S Cell division protein FtsN
FADFFPFK_02526 7.4e-58 sipW 3.4.21.89 U Signal peptidase
FADFFPFK_02527 5.1e-115 yqxM
FADFFPFK_02528 2.1e-53 yqzG S Protein of unknown function (DUF3889)
FADFFPFK_02529 1.4e-26 yqzE S YqzE-like protein
FADFFPFK_02530 3e-44 S ComG operon protein 7
FADFFPFK_02531 1.7e-34 comGF U Putative Competence protein ComGF
FADFFPFK_02532 9e-59 comGE
FADFFPFK_02533 5.4e-69 gspH NU protein transport across the cell outer membrane
FADFFPFK_02534 1.5e-46 comGC U Required for transformation and DNA binding
FADFFPFK_02535 2.6e-170 comGB NU COG1459 Type II secretory pathway, component PulF
FADFFPFK_02536 4.3e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FADFFPFK_02538 7.2e-175 corA P Mg2 transporter protein
FADFFPFK_02539 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
FADFFPFK_02540 1.1e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FADFFPFK_02542 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
FADFFPFK_02543 1.8e-37 yqgY S Protein of unknown function (DUF2626)
FADFFPFK_02544 8e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
FADFFPFK_02545 8.9e-23 yqgW S Protein of unknown function (DUF2759)
FADFFPFK_02546 2.6e-49 yqgV S Thiamine-binding protein
FADFFPFK_02547 3.3e-197 yqgU
FADFFPFK_02548 2.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
FADFFPFK_02549 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FADFFPFK_02550 5.2e-181 glcK 2.7.1.2 G Glucokinase
FADFFPFK_02551 3.1e-33 yqgQ S Protein conserved in bacteria
FADFFPFK_02552 3.2e-265 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
FADFFPFK_02553 2.5e-09 yqgO
FADFFPFK_02554 1.1e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FADFFPFK_02555 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FADFFPFK_02556 1.6e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
FADFFPFK_02558 2.1e-50 yqzD
FADFFPFK_02559 7e-75 yqzC S YceG-like family
FADFFPFK_02560 1.9e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FADFFPFK_02561 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FADFFPFK_02562 1.3e-157 pstA P Phosphate transport system permease
FADFFPFK_02563 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
FADFFPFK_02564 9e-143 pstS P Phosphate
FADFFPFK_02565 0.0 pbpA 3.4.16.4 M penicillin-binding protein
FADFFPFK_02566 2.5e-231 yqgE EGP Major facilitator superfamily
FADFFPFK_02567 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
FADFFPFK_02568 4e-73 yqgC S protein conserved in bacteria
FADFFPFK_02569 3.9e-131 yqgB S Protein of unknown function (DUF1189)
FADFFPFK_02570 5.2e-47 yqfZ M LysM domain
FADFFPFK_02571 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FADFFPFK_02572 4.3e-62 yqfX S membrane
FADFFPFK_02573 2.7e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
FADFFPFK_02574 4.2e-77 zur P Belongs to the Fur family
FADFFPFK_02575 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
FADFFPFK_02576 2.1e-36 yqfT S Protein of unknown function (DUF2624)
FADFFPFK_02577 2.4e-150 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FADFFPFK_02578 2.1e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
FADFFPFK_02579 6.1e-12 yqfQ S YqfQ-like protein
FADFFPFK_02580 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FADFFPFK_02581 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FADFFPFK_02582 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
FADFFPFK_02583 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
FADFFPFK_02584 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FADFFPFK_02585 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
FADFFPFK_02586 1.7e-87 yaiI S Belongs to the UPF0178 family
FADFFPFK_02587 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
FADFFPFK_02588 4.5e-112 ccpN K CBS domain
FADFFPFK_02589 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
FADFFPFK_02590 5.7e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
FADFFPFK_02591 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
FADFFPFK_02592 8.4e-19 S YqzL-like protein
FADFFPFK_02593 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FADFFPFK_02594 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
FADFFPFK_02595 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
FADFFPFK_02596 6.7e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FADFFPFK_02597 0.0 yqfF S membrane-associated HD superfamily hydrolase
FADFFPFK_02599 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
FADFFPFK_02600 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
FADFFPFK_02601 2.7e-45 yqfC S sporulation protein YqfC
FADFFPFK_02602 1.5e-23 yqfB
FADFFPFK_02603 3.7e-121 yqfA S UPF0365 protein
FADFFPFK_02604 5e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
FADFFPFK_02605 2.5e-61 yqeY S Yqey-like protein
FADFFPFK_02606 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
FADFFPFK_02607 1e-154 yqeW P COG1283 Na phosphate symporter
FADFFPFK_02608 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
FADFFPFK_02609 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
FADFFPFK_02610 5.4e-175 prmA J Methylates ribosomal protein L11
FADFFPFK_02611 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FADFFPFK_02612 0.0 dnaK O Heat shock 70 kDa protein
FADFFPFK_02613 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FADFFPFK_02614 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
FADFFPFK_02615 3.5e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
FADFFPFK_02616 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FADFFPFK_02617 4.7e-52 yqxA S Protein of unknown function (DUF3679)
FADFFPFK_02618 1.5e-222 spoIIP M stage II sporulation protein P
FADFFPFK_02619 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FADFFPFK_02620 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
FADFFPFK_02621 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
FADFFPFK_02622 4.1e-15 S YqzM-like protein
FADFFPFK_02623 0.0 comEC S Competence protein ComEC
FADFFPFK_02624 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
FADFFPFK_02625 6.2e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
FADFFPFK_02626 2.1e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FADFFPFK_02627 9.4e-138 yqeM Q Methyltransferase
FADFFPFK_02628 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FADFFPFK_02629 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
FADFFPFK_02630 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FADFFPFK_02631 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
FADFFPFK_02632 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FADFFPFK_02633 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
FADFFPFK_02634 5.3e-95 yqeG S hydrolase of the HAD superfamily
FADFFPFK_02636 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
FADFFPFK_02637 5.4e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FADFFPFK_02638 1.8e-105 yqeD S SNARE associated Golgi protein
FADFFPFK_02639 1e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
FADFFPFK_02640 6.3e-131 yqeB
FADFFPFK_02641 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
FADFFPFK_02642 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FADFFPFK_02643 1.4e-15 cisA2 L Recombinase
FADFFPFK_02644 4.4e-258 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
FADFFPFK_02645 5e-154 K Transcriptional regulator
FADFFPFK_02646 3.6e-160 ydhE CG UDP-glucoronosyl and UDP-glucosyl transferase
FADFFPFK_02647 7.2e-72 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
FADFFPFK_02648 1.2e-205 EGP Major Facilitator Superfamily
FADFFPFK_02649 3.5e-78 P Major Facilitator Superfamily
FADFFPFK_02650 6.9e-171 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FADFFPFK_02651 2.2e-59 mdaB S Flavodoxin-like fold
FADFFPFK_02652 2.3e-79 yvbU K Transcriptional regulator
FADFFPFK_02653 3.4e-176 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
FADFFPFK_02655 5.6e-65 S response regulator aspartate phosphatase
FADFFPFK_02657 1.9e-226 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
FADFFPFK_02658 1.1e-26 yokK S SMI1 / KNR4 family
FADFFPFK_02659 8.5e-30 S SMI1 / KNR4 family
FADFFPFK_02660 2.8e-47
FADFFPFK_02661 1.4e-40
FADFFPFK_02663 2e-102 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
FADFFPFK_02665 3.1e-26 S phage terminase, large subunit
FADFFPFK_02666 1.7e-76 yqaS L DNA packaging
FADFFPFK_02667 1.9e-95
FADFFPFK_02668 6.9e-75 L Transposase
FADFFPFK_02669 2.7e-31
FADFFPFK_02670 4.7e-125 S Beta protein
FADFFPFK_02671 9.7e-66 S Psort location Cytoplasmic, score
FADFFPFK_02672 6.8e-30 yqaO S Phage-like element PBSX protein XtrA
FADFFPFK_02673 2.6e-71 rusA L Endodeoxyribonuclease RusA
FADFFPFK_02676 3.2e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
FADFFPFK_02677 3e-90 K Transcriptional regulator PadR-like family
FADFFPFK_02678 5.9e-180 yjlA EG Putative multidrug resistance efflux transporter
FADFFPFK_02679 1.9e-111 K COG1802 Transcriptional regulators
FADFFPFK_02680 5.4e-112 yrkJ S membrane transporter protein
FADFFPFK_02681 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
FADFFPFK_02682 2.7e-205 yrkH P Rhodanese Homology Domain
FADFFPFK_02683 1.2e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
FADFFPFK_02684 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
FADFFPFK_02685 7.8e-39 yrkD S protein conserved in bacteria
FADFFPFK_02686 5e-21
FADFFPFK_02687 4.9e-107 yrkC G Cupin domain
FADFFPFK_02689 3.2e-147 bltR K helix_turn_helix, mercury resistance
FADFFPFK_02690 8.7e-210 blt EGP Major facilitator Superfamily
FADFFPFK_02691 3.8e-81 bltD 2.3.1.57 K FR47-like protein
FADFFPFK_02692 3.3e-231 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
FADFFPFK_02693 3.9e-16 S YrzO-like protein
FADFFPFK_02694 6e-169 yrdR EG EamA-like transporter family
FADFFPFK_02695 1.1e-158 yrdQ K Transcriptional regulator
FADFFPFK_02696 5.6e-197 trkA P Oxidoreductase
FADFFPFK_02697 6.5e-144 czcD P COG1230 Co Zn Cd efflux system component
FADFFPFK_02698 8.6e-66 yodA S tautomerase
FADFFPFK_02699 1.2e-160 gltR K LysR substrate binding domain
FADFFPFK_02700 4.5e-52 C COG2041 Sulfite oxidase and related enzymes
FADFFPFK_02701 3.2e-229 brnQ E Component of the transport system for branched-chain amino acids
FADFFPFK_02702 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
FADFFPFK_02703 5.3e-136 azlC E AzlC protein
FADFFPFK_02704 6.3e-79 bkdR K helix_turn_helix ASNC type
FADFFPFK_02705 6.5e-44 yrdF K ribonuclease inhibitor
FADFFPFK_02706 1.6e-222 cypA C Cytochrome P450
FADFFPFK_02707 1.9e-39 K Acetyltransferase (GNAT) family
FADFFPFK_02708 7.9e-65 K Transcriptional regulator
FADFFPFK_02709 1.2e-164 scrR K transcriptional
FADFFPFK_02710 6.9e-229 msmE G Bacterial extracellular solute-binding protein
FADFFPFK_02711 3.9e-149 msmF P Binding-protein-dependent transport system inner membrane component
FADFFPFK_02712 1.1e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
FADFFPFK_02713 6.1e-198 rafB P LacY proton/sugar symporter
FADFFPFK_02714 4.4e-251 cscA 3.2.1.26 GH32 G invertase
FADFFPFK_02715 4.6e-148 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
FADFFPFK_02716 5.5e-74 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
FADFFPFK_02717 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
FADFFPFK_02718 4e-55 S Protein of unknown function (DUF2568)
FADFFPFK_02720 7.1e-89 yrdA S DinB family
FADFFPFK_02721 2.7e-165 aadK G Streptomycin adenylyltransferase
FADFFPFK_02722 4.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
FADFFPFK_02723 3.8e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
FADFFPFK_02724 1.6e-123 yrpD S Domain of unknown function, YrpD
FADFFPFK_02725 1.9e-98 flr S Flavin reductase like domain
FADFFPFK_02726 3.6e-117 bmrR K helix_turn_helix, mercury resistance
FADFFPFK_02727 1.6e-49 yjbR S YjbR
FADFFPFK_02728 2.7e-24 epsA I Passenger-associated-transport-repeat
FADFFPFK_02729 1.3e-113 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
FADFFPFK_02730 2.3e-93 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
FADFFPFK_02731 1.8e-184 yrpG C Aldo/keto reductase family
FADFFPFK_02732 2.9e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
FADFFPFK_02733 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FADFFPFK_02734 1.8e-150 S Alpha beta hydrolase
FADFFPFK_02735 2.2e-60 T sh3 domain protein
FADFFPFK_02736 7.6e-61 T sh3 domain protein
FADFFPFK_02737 3e-63 E Glyoxalase-like domain
FADFFPFK_02738 1.5e-36 yraG
FADFFPFK_02739 6.4e-63 yraF M Spore coat protein
FADFFPFK_02740 5.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
FADFFPFK_02741 7.5e-26 yraE
FADFFPFK_02742 1.1e-47 yraD M Spore coat protein
FADFFPFK_02743 4.3e-47 yraB K helix_turn_helix, mercury resistance
FADFFPFK_02744 1.6e-25 yphJ 4.1.1.44 S peroxiredoxin activity
FADFFPFK_02745 2.1e-196 adhA 1.1.1.1 C alcohol dehydrogenase
FADFFPFK_02746 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
FADFFPFK_02747 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
FADFFPFK_02748 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
FADFFPFK_02749 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
FADFFPFK_02750 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
FADFFPFK_02751 1.5e-74 levD 2.7.1.202 G PTS system fructose IIA component
FADFFPFK_02752 0.0 levR K PTS system fructose IIA component
FADFFPFK_02753 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
FADFFPFK_02754 1.1e-105 yrhP E LysE type translocator
FADFFPFK_02755 7e-150 yrhO K Archaeal transcriptional regulator TrmB
FADFFPFK_02756 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
FADFFPFK_02757 7.2e-150 rsiV S Protein of unknown function (DUF3298)
FADFFPFK_02758 0.0 yrhL I Acyltransferase family
FADFFPFK_02759 9.1e-44 yrhK S YrhK-like protein
FADFFPFK_02760 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
FADFFPFK_02761 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
FADFFPFK_02762 3.2e-95 yrhH Q methyltransferase
FADFFPFK_02764 3e-142 focA P Formate nitrite
FADFFPFK_02765 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
FADFFPFK_02766 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
FADFFPFK_02767 2.1e-77 yrhD S Protein of unknown function (DUF1641)
FADFFPFK_02768 4.6e-35 yrhC S YrhC-like protein
FADFFPFK_02769 9.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FADFFPFK_02770 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
FADFFPFK_02771 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FADFFPFK_02772 1.9e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
FADFFPFK_02773 1e-25 yrzA S Protein of unknown function (DUF2536)
FADFFPFK_02774 1.6e-62 yrrS S Protein of unknown function (DUF1510)
FADFFPFK_02775 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
FADFFPFK_02776 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FADFFPFK_02777 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
FADFFPFK_02778 2.7e-246 yegQ O COG0826 Collagenase and related proteases
FADFFPFK_02779 4.3e-172 yegQ O Peptidase U32
FADFFPFK_02780 8.6e-119 yrrM 2.1.1.104 S O-methyltransferase
FADFFPFK_02781 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FADFFPFK_02782 1.2e-45 yrzB S Belongs to the UPF0473 family
FADFFPFK_02783 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FADFFPFK_02784 1.7e-41 yrzL S Belongs to the UPF0297 family
FADFFPFK_02785 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FADFFPFK_02786 2.7e-170 yrrI S AI-2E family transporter
FADFFPFK_02787 1.2e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FADFFPFK_02788 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
FADFFPFK_02789 1.8e-108 gluC P ABC transporter
FADFFPFK_02790 7.6e-107 glnP P ABC transporter
FADFFPFK_02791 8e-08 S Protein of unknown function (DUF3918)
FADFFPFK_02792 9.8e-31 yrzR
FADFFPFK_02793 6.6e-81 yrrD S protein conserved in bacteria
FADFFPFK_02794 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
FADFFPFK_02795 1.4e-15 S COG0457 FOG TPR repeat
FADFFPFK_02796 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FADFFPFK_02797 4.4e-211 iscS 2.8.1.7 E Cysteine desulfurase
FADFFPFK_02798 1.2e-70 cymR K Transcriptional regulator
FADFFPFK_02799 9.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
FADFFPFK_02800 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
FADFFPFK_02801 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FADFFPFK_02802 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
FADFFPFK_02804 2.9e-258 lytH 3.5.1.28 M COG3103 SH3 domain protein
FADFFPFK_02805 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FADFFPFK_02806 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FADFFPFK_02807 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FADFFPFK_02808 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
FADFFPFK_02809 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
FADFFPFK_02810 2.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
FADFFPFK_02811 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FADFFPFK_02812 1.6e-48 yrzD S Post-transcriptional regulator
FADFFPFK_02813 9.1e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FADFFPFK_02814 7.1e-113 yrbG S membrane
FADFFPFK_02815 1.5e-74 yrzE S Protein of unknown function (DUF3792)
FADFFPFK_02816 8e-39 yajC U Preprotein translocase subunit YajC
FADFFPFK_02817 1.2e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
FADFFPFK_02818 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FADFFPFK_02819 2.6e-18 yrzS S Protein of unknown function (DUF2905)
FADFFPFK_02820 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
FADFFPFK_02821 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
FADFFPFK_02822 4.8e-93 bofC S BofC C-terminal domain
FADFFPFK_02823 5.3e-253 csbX EGP Major facilitator Superfamily
FADFFPFK_02824 1.2e-191 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
FADFFPFK_02825 6.5e-119 yrzF T serine threonine protein kinase
FADFFPFK_02827 1.2e-50 S Family of unknown function (DUF5412)
FADFFPFK_02828 4.5e-261 alsT E Sodium alanine symporter
FADFFPFK_02829 3.6e-126 yebC K transcriptional regulatory protein
FADFFPFK_02830 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FADFFPFK_02831 1.8e-156 safA M spore coat assembly protein SafA
FADFFPFK_02832 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FADFFPFK_02833 1.1e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
FADFFPFK_02834 7.5e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
FADFFPFK_02835 1.8e-228 nifS 2.8.1.7 E Cysteine desulfurase
FADFFPFK_02836 5.1e-93 niaR S small molecule binding protein (contains 3H domain)
FADFFPFK_02837 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
FADFFPFK_02838 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
FADFFPFK_02839 2.8e-230 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FADFFPFK_02840 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
FADFFPFK_02841 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
FADFFPFK_02842 4.1e-56 ysxB J ribosomal protein
FADFFPFK_02843 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
FADFFPFK_02844 2e-160 spoIVFB S Stage IV sporulation protein
FADFFPFK_02845 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
FADFFPFK_02846 2.5e-144 minD D Belongs to the ParA family
FADFFPFK_02847 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
FADFFPFK_02848 1.4e-84 mreD M shape-determining protein
FADFFPFK_02849 1.1e-156 mreC M Involved in formation and maintenance of cell shape
FADFFPFK_02850 1.8e-184 mreB D Rod shape-determining protein MreB
FADFFPFK_02851 1.3e-125 radC E Belongs to the UPF0758 family
FADFFPFK_02852 8.3e-102 maf D septum formation protein Maf
FADFFPFK_02853 7.3e-162 spoIIB S Sporulation related domain
FADFFPFK_02854 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
FADFFPFK_02855 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
FADFFPFK_02856 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FADFFPFK_02857 1.6e-25
FADFFPFK_02858 2.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FADFFPFK_02859 4.1e-213 spoVID M stage VI sporulation protein D
FADFFPFK_02860 5.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
FADFFPFK_02861 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
FADFFPFK_02862 4.2e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
FADFFPFK_02863 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
FADFFPFK_02864 3.6e-146 hemX O cytochrome C
FADFFPFK_02865 2.3e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FADFFPFK_02866 1.4e-89 ysxD
FADFFPFK_02867 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
FADFFPFK_02868 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FADFFPFK_02869 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
FADFFPFK_02870 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FADFFPFK_02871 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FADFFPFK_02872 8.6e-187 ysoA H Tetratricopeptide repeat
FADFFPFK_02873 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FADFFPFK_02874 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FADFFPFK_02875 2.2e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
FADFFPFK_02876 9.3e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FADFFPFK_02877 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FADFFPFK_02878 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
FADFFPFK_02879 0.0 ilvB 2.2.1.6 E Acetolactate synthase
FADFFPFK_02881 3.1e-75 ysnE K acetyltransferase
FADFFPFK_02882 1.5e-135 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FADFFPFK_02883 5.5e-131 ysnF S protein conserved in bacteria
FADFFPFK_02885 3.1e-92 ysnB S Phosphoesterase
FADFFPFK_02886 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FADFFPFK_02887 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FADFFPFK_02888 1.2e-194 gerM S COG5401 Spore germination protein
FADFFPFK_02889 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
FADFFPFK_02890 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
FADFFPFK_02891 3.3e-30 gerE K Transcriptional regulator
FADFFPFK_02892 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
FADFFPFK_02893 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
FADFFPFK_02894 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
FADFFPFK_02895 2.4e-107 sdhC C succinate dehydrogenase
FADFFPFK_02896 1.2e-79 yslB S Protein of unknown function (DUF2507)
FADFFPFK_02897 1.8e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
FADFFPFK_02898 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FADFFPFK_02899 2e-52 trxA O Belongs to the thioredoxin family
FADFFPFK_02900 1.3e-300 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
FADFFPFK_02901 1.5e-175 etfA C Electron transfer flavoprotein
FADFFPFK_02902 4.5e-135 etfB C Electron transfer flavoprotein
FADFFPFK_02903 1.7e-134 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
FADFFPFK_02904 4e-99 fadR K Transcriptional regulator
FADFFPFK_02905 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
FADFFPFK_02906 7.3e-68 yshE S membrane
FADFFPFK_02907 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FADFFPFK_02908 0.0 polX L COG1796 DNA polymerase IV (family X)
FADFFPFK_02909 1.7e-85 cvpA S membrane protein, required for colicin V production
FADFFPFK_02910 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FADFFPFK_02911 2.6e-169 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FADFFPFK_02912 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FADFFPFK_02913 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FADFFPFK_02914 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FADFFPFK_02915 5.8e-32 sspI S Belongs to the SspI family
FADFFPFK_02916 6.6e-204 ysfB KT regulator
FADFFPFK_02917 2.4e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
FADFFPFK_02918 1.5e-255 glcF C Glycolate oxidase
FADFFPFK_02919 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
FADFFPFK_02920 0.0 cstA T Carbon starvation protein
FADFFPFK_02921 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
FADFFPFK_02922 3.8e-143 araQ G transport system permease
FADFFPFK_02923 1.4e-167 araP G carbohydrate transport
FADFFPFK_02924 4.9e-251 araN G carbohydrate transport
FADFFPFK_02925 5.2e-223 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
FADFFPFK_02926 2.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
FADFFPFK_02927 2.4e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
FADFFPFK_02928 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
FADFFPFK_02929 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
FADFFPFK_02930 8.9e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
FADFFPFK_02931 3.8e-204 ysdC G COG1363 Cellulase M and related proteins
FADFFPFK_02932 9.2e-68 ysdB S Sigma-w pathway protein YsdB
FADFFPFK_02933 7.5e-45 ysdA S Membrane
FADFFPFK_02934 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FADFFPFK_02935 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
FADFFPFK_02936 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FADFFPFK_02938 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
FADFFPFK_02939 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
FADFFPFK_02940 7e-130 lytT T COG3279 Response regulator of the LytR AlgR family
FADFFPFK_02941 0.0 lytS 2.7.13.3 T Histidine kinase
FADFFPFK_02942 7.3e-149 ysaA S HAD-hyrolase-like
FADFFPFK_02943 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FADFFPFK_02945 1.6e-157 ytxC S YtxC-like family
FADFFPFK_02946 1.1e-107 ytxB S SNARE associated Golgi protein
FADFFPFK_02947 1.1e-172 dnaI L Primosomal protein DnaI
FADFFPFK_02948 4.5e-266 dnaB L Membrane attachment protein
FADFFPFK_02949 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FADFFPFK_02950 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FADFFPFK_02951 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FADFFPFK_02952 9.9e-67 ytcD K Transcriptional regulator
FADFFPFK_02953 2.4e-204 ytbD EGP Major facilitator Superfamily
FADFFPFK_02954 8.9e-161 ytbE S reductase
FADFFPFK_02955 5.4e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FADFFPFK_02956 1.1e-107 ytaF P Probably functions as a manganese efflux pump
FADFFPFK_02957 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
FADFFPFK_02958 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FADFFPFK_02959 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
FADFFPFK_02960 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_02961 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
FADFFPFK_02962 4.1e-242 icd 1.1.1.42 C isocitrate
FADFFPFK_02963 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
FADFFPFK_02964 4.7e-71 yeaL S membrane
FADFFPFK_02965 3.4e-192 ytvI S sporulation integral membrane protein YtvI
FADFFPFK_02966 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
FADFFPFK_02967 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
FADFFPFK_02968 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
FADFFPFK_02969 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
FADFFPFK_02970 2.4e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FADFFPFK_02971 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
FADFFPFK_02972 0.0 dnaE 2.7.7.7 L DNA polymerase
FADFFPFK_02973 3.2e-56 ytrH S Sporulation protein YtrH
FADFFPFK_02974 8.2e-69 ytrI
FADFFPFK_02975 9.2e-29
FADFFPFK_02976 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
FADFFPFK_02977 2.4e-47 ytpI S YtpI-like protein
FADFFPFK_02978 3e-240 ytoI K transcriptional regulator containing CBS domains
FADFFPFK_02979 2.7e-155 ytnM S membrane transporter protein
FADFFPFK_02980 3e-237 ytnL 3.5.1.47 E hydrolase activity
FADFFPFK_02981 2e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
FADFFPFK_02982 2.6e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FADFFPFK_02983 7.1e-46 ytnI O COG0695 Glutaredoxin and related proteins
FADFFPFK_02984 4.4e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FADFFPFK_02985 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FADFFPFK_02986 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
FADFFPFK_02987 1.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
FADFFPFK_02988 6.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
FADFFPFK_02989 1.8e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
FADFFPFK_02990 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
FADFFPFK_02991 1.9e-172 ytlI K LysR substrate binding domain
FADFFPFK_02992 1.7e-130 ytkL S Belongs to the UPF0173 family
FADFFPFK_02993 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FADFFPFK_02995 1.2e-266 argH 4.3.2.1 E argininosuccinate lyase
FADFFPFK_02996 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
FADFFPFK_02997 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
FADFFPFK_02998 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FADFFPFK_02999 2.7e-164 ytxK 2.1.1.72 L DNA methylase
FADFFPFK_03000 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FADFFPFK_03001 8.7e-70 ytfJ S Sporulation protein YtfJ
FADFFPFK_03002 5.6e-116 ytfI S Protein of unknown function (DUF2953)
FADFFPFK_03003 8.5e-87 yteJ S RDD family
FADFFPFK_03004 1.8e-179 sppA OU signal peptide peptidase SppA
FADFFPFK_03005 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FADFFPFK_03006 0.0 ytcJ S amidohydrolase
FADFFPFK_03007 2.3e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
FADFFPFK_03008 2e-29 sspB S spore protein
FADFFPFK_03009 8.7e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FADFFPFK_03010 6.6e-207 iscS2 2.8.1.7 E Cysteine desulfurase
FADFFPFK_03011 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
FADFFPFK_03012 1e-272 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FADFFPFK_03013 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
FADFFPFK_03014 1.7e-108 yttP K Transcriptional regulator
FADFFPFK_03015 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
FADFFPFK_03016 2.2e-310 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
FADFFPFK_03017 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FADFFPFK_03019 7.5e-236 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FADFFPFK_03020 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
FADFFPFK_03021 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
FADFFPFK_03022 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
FADFFPFK_03023 3.5e-224 acuC BQ histone deacetylase
FADFFPFK_03024 5.2e-125 motS N Flagellar motor protein
FADFFPFK_03025 2.1e-146 motA N flagellar motor
FADFFPFK_03026 3.8e-182 ccpA K catabolite control protein A
FADFFPFK_03027 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
FADFFPFK_03028 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
FADFFPFK_03029 6.6e-17 ytxH S COG4980 Gas vesicle protein
FADFFPFK_03030 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FADFFPFK_03031 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
FADFFPFK_03032 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
FADFFPFK_03033 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FADFFPFK_03034 9.8e-149 ytpQ S Belongs to the UPF0354 family
FADFFPFK_03035 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
FADFFPFK_03036 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
FADFFPFK_03037 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
FADFFPFK_03038 2.2e-51 ytzB S small secreted protein
FADFFPFK_03039 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
FADFFPFK_03040 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
FADFFPFK_03041 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
FADFFPFK_03042 2e-45 ytzH S YtzH-like protein
FADFFPFK_03043 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
FADFFPFK_03044 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
FADFFPFK_03045 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
FADFFPFK_03046 1.3e-165 ytlQ
FADFFPFK_03047 1.4e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FADFFPFK_03048 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FADFFPFK_03049 3e-270 pepV 3.5.1.18 E Dipeptidase
FADFFPFK_03050 1.8e-224 pbuO S permease
FADFFPFK_03051 8.4e-202 ythQ U Bacterial ABC transporter protein EcsB
FADFFPFK_03052 4.8e-131 ythP V ABC transporter
FADFFPFK_03053 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
FADFFPFK_03054 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FADFFPFK_03055 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FADFFPFK_03056 2.4e-231 ytfP S HI0933-like protein
FADFFPFK_03057 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
FADFFPFK_03058 3.1e-26 yteV S Sporulation protein Cse60
FADFFPFK_03059 4.8e-117 yteU S Integral membrane protein
FADFFPFK_03060 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
FADFFPFK_03061 4.6e-73 yteS G transport
FADFFPFK_03062 2.6e-224 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
FADFFPFK_03063 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
FADFFPFK_03064 0.0 ytdP K Transcriptional regulator
FADFFPFK_03065 8.9e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
FADFFPFK_03066 2.3e-151 ytcP G COG0395 ABC-type sugar transport system, permease component
FADFFPFK_03067 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
FADFFPFK_03068 1.2e-219 bioI 1.14.14.46 C Cytochrome P450
FADFFPFK_03069 1.2e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FADFFPFK_03070 4.2e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FADFFPFK_03071 1.6e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
FADFFPFK_03072 1.5e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
FADFFPFK_03073 1.5e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
FADFFPFK_03074 2.4e-172 ytaP S Acetyl xylan esterase (AXE1)
FADFFPFK_03075 1.5e-186 msmR K Transcriptional regulator
FADFFPFK_03076 9.8e-244 msmE G Bacterial extracellular solute-binding protein
FADFFPFK_03077 2.4e-167 amyD P ABC transporter
FADFFPFK_03078 4.4e-144 amyC P ABC transporter (permease)
FADFFPFK_03079 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
FADFFPFK_03080 2.1e-51 ytwF P Sulfurtransferase
FADFFPFK_03081 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
FADFFPFK_03082 7.7e-55 ytvB S Protein of unknown function (DUF4257)
FADFFPFK_03083 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
FADFFPFK_03084 3e-210 yttB EGP Major facilitator Superfamily
FADFFPFK_03085 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
FADFFPFK_03086 0.0 bceB V ABC transporter (permease)
FADFFPFK_03087 1.1e-138 bceA V ABC transporter, ATP-binding protein
FADFFPFK_03088 1.6e-185 T PhoQ Sensor
FADFFPFK_03089 1.2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_03090 1.9e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
FADFFPFK_03091 1.6e-126 ytrE V ABC transporter, ATP-binding protein
FADFFPFK_03092 3.1e-149
FADFFPFK_03093 1.3e-150 P ABC-2 family transporter protein
FADFFPFK_03094 4.2e-161 ytrB P abc transporter atp-binding protein
FADFFPFK_03095 5.1e-66 ytrA K GntR family transcriptional regulator
FADFFPFK_03097 6.7e-41 ytzC S Protein of unknown function (DUF2524)
FADFFPFK_03098 2.3e-189 yhcC S Fe-S oxidoreductase
FADFFPFK_03099 9.7e-106 ytqB J Putative rRNA methylase
FADFFPFK_03100 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
FADFFPFK_03101 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
FADFFPFK_03102 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FADFFPFK_03103 1.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
FADFFPFK_03104 0.0 asnB 6.3.5.4 E Asparagine synthase
FADFFPFK_03105 1.2e-224 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FADFFPFK_03106 2.6e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FADFFPFK_03107 1.2e-38 ytmB S Protein of unknown function (DUF2584)
FADFFPFK_03108 4.4e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
FADFFPFK_03109 8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
FADFFPFK_03110 1.4e-144 ytlC P ABC transporter
FADFFPFK_03111 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
FADFFPFK_03112 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
FADFFPFK_03113 7.8e-62 ytkC S Bacteriophage holin family
FADFFPFK_03114 2.1e-76 dps P Belongs to the Dps family
FADFFPFK_03116 2.4e-72 ytkA S YtkA-like
FADFFPFK_03117 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FADFFPFK_03118 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
FADFFPFK_03119 6.1e-41 rpmE2 J Ribosomal protein L31
FADFFPFK_03120 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
FADFFPFK_03121 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
FADFFPFK_03122 1.1e-24 S Domain of Unknown Function (DUF1540)
FADFFPFK_03123 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
FADFFPFK_03124 3.7e-230 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
FADFFPFK_03125 7.3e-138 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
FADFFPFK_03126 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
FADFFPFK_03127 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
FADFFPFK_03128 3.9e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
FADFFPFK_03129 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FADFFPFK_03130 1e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
FADFFPFK_03131 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FADFFPFK_03132 2.7e-271 menF 5.4.4.2 HQ Isochorismate synthase
FADFFPFK_03133 9.7e-132 dksA T COG1734 DnaK suppressor protein
FADFFPFK_03134 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
FADFFPFK_03135 3.7e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FADFFPFK_03136 1.7e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
FADFFPFK_03137 5.2e-234 ytcC M Glycosyltransferase Family 4
FADFFPFK_03139 1.6e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
FADFFPFK_03140 6.9e-217 cotSA M Glycosyl transferases group 1
FADFFPFK_03141 3.1e-203 cotI S Spore coat protein
FADFFPFK_03142 1.4e-75 tspO T membrane
FADFFPFK_03143 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
FADFFPFK_03144 1.1e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
FADFFPFK_03145 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
FADFFPFK_03146 8.9e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FADFFPFK_03147 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FADFFPFK_03156 7.8e-08
FADFFPFK_03157 1.3e-09
FADFFPFK_03164 4.6e-157 ydhU P Catalase
FADFFPFK_03165 4.9e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
FADFFPFK_03166 4.5e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
FADFFPFK_03167 2.3e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
FADFFPFK_03168 1.3e-131 ydhQ K UTRA
FADFFPFK_03169 5.2e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FADFFPFK_03170 4.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FADFFPFK_03171 1.3e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
FADFFPFK_03172 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
FADFFPFK_03173 4.6e-200 pbuE EGP Major facilitator Superfamily
FADFFPFK_03174 2.5e-98 ydhK M Protein of unknown function (DUF1541)
FADFFPFK_03175 2.8e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
FADFFPFK_03176 8.6e-84 K Acetyltransferase (GNAT) domain
FADFFPFK_03178 1.1e-67 frataxin S Domain of unknown function (DU1801)
FADFFPFK_03179 9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
FADFFPFK_03180 8.7e-125
FADFFPFK_03181 1.3e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
FADFFPFK_03182 2.4e-242 ydhD M Glycosyl hydrolase
FADFFPFK_03183 3.2e-121 ydhC K FCD
FADFFPFK_03184 1.2e-121 ydhB S membrane transporter protein
FADFFPFK_03185 2.2e-208 tcaB EGP Major facilitator Superfamily
FADFFPFK_03186 2.4e-69 ydgJ K Winged helix DNA-binding domain
FADFFPFK_03187 1e-113 drgA C nitroreductase
FADFFPFK_03188 0.0 ydgH S drug exporters of the RND superfamily
FADFFPFK_03189 1.5e-78 K helix_turn_helix multiple antibiotic resistance protein
FADFFPFK_03190 4.7e-88 dinB S DinB family
FADFFPFK_03191 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
FADFFPFK_03192 9.8e-305 expZ S ABC transporter
FADFFPFK_03193 4.6e-82 yycN 2.3.1.128 K Acetyltransferase
FADFFPFK_03194 1.4e-51 S DoxX-like family
FADFFPFK_03195 7.6e-98 K Bacterial regulatory proteins, tetR family
FADFFPFK_03196 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
FADFFPFK_03197 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
FADFFPFK_03198 3.2e-74 cotP O Belongs to the small heat shock protein (HSP20) family
FADFFPFK_03199 2.6e-121 ydfS S Protein of unknown function (DUF421)
FADFFPFK_03200 1.9e-99 ydfR S Protein of unknown function (DUF421)
FADFFPFK_03202 6.3e-29
FADFFPFK_03203 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
FADFFPFK_03204 1.7e-54 traF CO Thioredoxin
FADFFPFK_03205 8.8e-63 mhqP S DoxX
FADFFPFK_03206 6.8e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
FADFFPFK_03207 1.1e-110 ydfN C nitroreductase
FADFFPFK_03208 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FADFFPFK_03209 2.8e-144 K Bacterial transcription activator, effector binding domain
FADFFPFK_03210 1.9e-116 S Protein of unknown function (DUF554)
FADFFPFK_03211 3.4e-174 S Alpha/beta hydrolase family
FADFFPFK_03212 0.0 ydfJ S drug exporters of the RND superfamily
FADFFPFK_03213 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FADFFPFK_03214 1.1e-178 ydfH 2.7.13.3 T Histidine kinase
FADFFPFK_03216 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FADFFPFK_03217 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
FADFFPFK_03218 4.2e-115 ydfE S Flavin reductase like domain
FADFFPFK_03219 5.6e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FADFFPFK_03220 2.8e-144 ydfC EG EamA-like transporter family
FADFFPFK_03221 2.9e-145 ydfB J GNAT acetyltransferase
FADFFPFK_03222 5.4e-50 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
FADFFPFK_03223 5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FADFFPFK_03224 6.5e-54 arsR K transcriptional
FADFFPFK_03225 3.5e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
FADFFPFK_03226 1.8e-56 K HxlR-like helix-turn-helix
FADFFPFK_03227 4.9e-102 ydeN S Serine hydrolase
FADFFPFK_03228 2.3e-72 maoC I N-terminal half of MaoC dehydratase
FADFFPFK_03229 1.6e-268 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FADFFPFK_03230 7e-153 ydeK EG -transporter
FADFFPFK_03231 2.6e-84 K Transcriptional regulator C-terminal region
FADFFPFK_03232 4.9e-15 ptsH G PTS HPr component phosphorylation site
FADFFPFK_03233 1.1e-31 S SNARE associated Golgi protein
FADFFPFK_03234 4.2e-97
FADFFPFK_03235 5.1e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
FADFFPFK_03236 2.7e-45 ydeH
FADFFPFK_03237 7.1e-218 ydeG EGP Major facilitator superfamily
FADFFPFK_03238 1.8e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FADFFPFK_03239 1.4e-164 ydeE K AraC family transcriptional regulator
FADFFPFK_03240 1.4e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
FADFFPFK_03241 9.9e-163 rhaS5 K AraC-like ligand binding domain
FADFFPFK_03242 1.2e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
FADFFPFK_03243 2.3e-78 carD K Transcription factor
FADFFPFK_03244 8.7e-30 cspL K Cold shock
FADFFPFK_03245 7.5e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
FADFFPFK_03246 9.6e-40
FADFFPFK_03247 3.4e-33 K Helix-turn-helix XRE-family like proteins
FADFFPFK_03248 4.5e-15 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
FADFFPFK_03249 5e-47 ydeH
FADFFPFK_03250 9e-208 msbA2 3.6.3.44 V ABC transporter
FADFFPFK_03251 9.8e-211 KLT Protein kinase domain
FADFFPFK_03257 3.1e-159 KLT Protein kinase domain
FADFFPFK_03269 3.4e-82 ydcK S Belongs to the SprT family
FADFFPFK_03270 0.0 yhgF K COG2183 Transcriptional accessory protein
FADFFPFK_03271 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
FADFFPFK_03272 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FADFFPFK_03273 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
FADFFPFK_03274 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
FADFFPFK_03275 7.1e-189 rsbU 3.1.3.3 KT phosphatase
FADFFPFK_03276 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
FADFFPFK_03277 5.2e-57 rsbS T antagonist
FADFFPFK_03278 1.3e-143 rsbR T Positive regulator of sigma-B
FADFFPFK_03279 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
FADFFPFK_03280 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
FADFFPFK_03281 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FADFFPFK_03282 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
FADFFPFK_03283 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
FADFFPFK_03284 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
FADFFPFK_03285 8.6e-260 ydbT S Membrane
FADFFPFK_03286 2.1e-82 ydbS S Bacterial PH domain
FADFFPFK_03287 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
FADFFPFK_03288 1.6e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
FADFFPFK_03289 1.1e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
FADFFPFK_03290 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
FADFFPFK_03291 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FADFFPFK_03292 2.2e-07 S Fur-regulated basic protein A
FADFFPFK_03293 1.1e-18 S Fur-regulated basic protein B
FADFFPFK_03294 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
FADFFPFK_03295 2.7e-52 ydbL
FADFFPFK_03296 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FADFFPFK_03297 1.3e-168 ydbJ V ABC transporter, ATP-binding protein
FADFFPFK_03298 4.4e-181 ydbI S AI-2E family transporter
FADFFPFK_03299 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FADFFPFK_03300 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
FADFFPFK_03301 3.1e-295 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
FADFFPFK_03302 9.6e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
FADFFPFK_03303 2.3e-153 ydbD P Catalase
FADFFPFK_03304 2e-61 ydbC S Domain of unknown function (DUF4937
FADFFPFK_03305 2.6e-58 ydbB G Cupin domain
FADFFPFK_03307 1.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
FADFFPFK_03308 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
FADFFPFK_03310 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
FADFFPFK_03311 9.4e-40
FADFFPFK_03313 1.4e-72 sdpB S Protein conserved in bacteria
FADFFPFK_03314 1.8e-27
FADFFPFK_03316 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
FADFFPFK_03317 4.4e-43 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
FADFFPFK_03318 0.0 ydaO E amino acid
FADFFPFK_03319 0.0 ydaN S Bacterial cellulose synthase subunit
FADFFPFK_03320 4.5e-233 ydaM M Glycosyl transferase family group 2
FADFFPFK_03321 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
FADFFPFK_03322 9.4e-150 ydaK T Diguanylate cyclase, GGDEF domain
FADFFPFK_03323 2.1e-207 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
FADFFPFK_03324 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FADFFPFK_03325 2.5e-74 lrpC K Transcriptional regulator
FADFFPFK_03326 4e-44 ydzA EGP Major facilitator Superfamily
FADFFPFK_03327 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
FADFFPFK_03328 6.8e-77 ydaG 1.4.3.5 S general stress protein
FADFFPFK_03329 2.3e-101 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FADFFPFK_03330 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
FADFFPFK_03331 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FADFFPFK_03332 2.7e-95 ydaC Q Methyltransferase domain
FADFFPFK_03333 2.1e-293 ydaB IQ acyl-CoA ligase
FADFFPFK_03334 0.0 mtlR K transcriptional regulator, MtlR
FADFFPFK_03335 8.1e-176 ydhF S Oxidoreductase
FADFFPFK_03336 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
FADFFPFK_03337 8e-47 yczJ S biosynthesis
FADFFPFK_03339 3.5e-117 ycsK E anatomical structure formation involved in morphogenesis
FADFFPFK_03340 2.7e-132 kipR K Transcriptional regulator
FADFFPFK_03341 2.4e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
FADFFPFK_03342 4.4e-132 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
FADFFPFK_03343 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
FADFFPFK_03344 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
FADFFPFK_03345 1.8e-139 ycsF S Belongs to the UPF0271 (lamB) family
FADFFPFK_03346 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
FADFFPFK_03348 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
FADFFPFK_03349 6.3e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
FADFFPFK_03350 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
FADFFPFK_03352 8.5e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
FADFFPFK_03353 1.3e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
FADFFPFK_03354 4.4e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
FADFFPFK_03355 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
FADFFPFK_03356 2.4e-51
FADFFPFK_03357 1.8e-104 ycnK K COG1349 Transcriptional regulators of sugar metabolism
FADFFPFK_03358 1.2e-307 ycnJ P protein, homolog of Cu resistance protein CopC
FADFFPFK_03359 1.4e-99 ycnI S protein conserved in bacteria
FADFFPFK_03360 7.8e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FADFFPFK_03361 1.8e-148 glcU U Glucose uptake
FADFFPFK_03362 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FADFFPFK_03363 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FADFFPFK_03364 2.1e-271 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FADFFPFK_03365 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
FADFFPFK_03366 1.6e-45 ycnE S Monooxygenase
FADFFPFK_03367 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
FADFFPFK_03368 6.5e-154 ycnC K Transcriptional regulator
FADFFPFK_03369 1.2e-250 ycnB EGP Major facilitator Superfamily
FADFFPFK_03370 7.2e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
FADFFPFK_03371 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
FADFFPFK_03372 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_03373 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_03374 1.6e-239 lysC 2.7.2.4 E Belongs to the aspartokinase family
FADFFPFK_03378 1.3e-77 S aspartate phosphatase
FADFFPFK_03379 4.9e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
FADFFPFK_03380 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_03381 1.1e-195 yclI V ABC transporter (permease) YclI
FADFFPFK_03382 1.9e-121 yclH P ABC transporter
FADFFPFK_03383 1.5e-195 gerKB F Spore germination protein
FADFFPFK_03384 2.4e-223 gerKC S spore germination
FADFFPFK_03385 2.4e-279 gerKA EG Spore germination protein
FADFFPFK_03387 1.8e-309 yclG M Pectate lyase superfamily protein
FADFFPFK_03388 8.1e-266 dtpT E amino acid peptide transporter
FADFFPFK_03389 1.9e-155 yclE 3.4.11.5 S Alpha beta hydrolase
FADFFPFK_03390 5.6e-80 yclD
FADFFPFK_03391 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
FADFFPFK_03392 4.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
FADFFPFK_03393 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
FADFFPFK_03394 1.9e-161 bsdA K LysR substrate binding domain
FADFFPFK_03395 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
FADFFPFK_03396 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
FADFFPFK_03397 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FADFFPFK_03398 9.7e-115 yczE S membrane
FADFFPFK_03399 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
FADFFPFK_03400 7.3e-250 ycxD K GntR family transcriptional regulator
FADFFPFK_03401 1.1e-159 ycxC EG EamA-like transporter family
FADFFPFK_03402 4.3e-87 S YcxB-like protein
FADFFPFK_03403 1.3e-224 EGP Major Facilitator Superfamily
FADFFPFK_03404 2.9e-139 srfAD Q thioesterase
FADFFPFK_03405 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
FADFFPFK_03406 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FADFFPFK_03407 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FADFFPFK_03408 1.3e-63 hxlR K transcriptional
FADFFPFK_03409 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
FADFFPFK_03410 3.9e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
FADFFPFK_03411 4.3e-186 tlpC 2.7.13.3 NT chemotaxis protein
FADFFPFK_03412 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
FADFFPFK_03413 1.1e-68 nin S Competence protein J (ComJ)
FADFFPFK_03414 4.9e-292 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FADFFPFK_03415 2.7e-121 S AAA domain
FADFFPFK_03416 9.3e-24
FADFFPFK_03417 3.1e-45 K MarR family
FADFFPFK_03418 7.8e-52 yckD S Protein of unknown function (DUF2680)
FADFFPFK_03419 2.8e-76 yckC S membrane
FADFFPFK_03421 1.7e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
FADFFPFK_03422 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
FADFFPFK_03423 3.5e-227 yciC S GTPases (G3E family)
FADFFPFK_03424 3e-107 yciB M ErfK YbiS YcfS YnhG
FADFFPFK_03425 1.3e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
FADFFPFK_03426 7.1e-220 nasA P COG2223 Nitrate nitrite transporter
FADFFPFK_03427 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
FADFFPFK_03428 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FADFFPFK_03429 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FADFFPFK_03430 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
FADFFPFK_03431 2.3e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
FADFFPFK_03432 1.4e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
FADFFPFK_03433 2.2e-159 I alpha/beta hydrolase fold
FADFFPFK_03434 1.2e-139 ycgR S permeases
FADFFPFK_03435 2.2e-146 ycgQ S membrane
FADFFPFK_03436 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
FADFFPFK_03437 5.9e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FADFFPFK_03438 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
FADFFPFK_03439 5.1e-170 ycgM E Proline dehydrogenase
FADFFPFK_03440 1.1e-144 ycgL S Predicted nucleotidyltransferase
FADFFPFK_03441 2.1e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
FADFFPFK_03442 1e-176 oxyR3 K LysR substrate binding domain
FADFFPFK_03443 1.1e-141 yafE Q ubiE/COQ5 methyltransferase family
FADFFPFK_03444 3.3e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FADFFPFK_03446 1.1e-107 tmrB S AAA domain
FADFFPFK_03447 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
FADFFPFK_03448 2.4e-112 ycgI S Domain of unknown function (DUF1989)
FADFFPFK_03449 1.1e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
FADFFPFK_03450 1.9e-149 yqcI S YqcI/YcgG family
FADFFPFK_03451 6.8e-113 ycgF E Lysine exporter protein LysE YggA
FADFFPFK_03452 7.5e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
FADFFPFK_03453 3.9e-263 mdr EGP Major facilitator Superfamily
FADFFPFK_03454 1.7e-100 lctP C L-lactate permease
FADFFPFK_03455 2.3e-153 lctP C L-lactate permease
FADFFPFK_03456 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
FADFFPFK_03457 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
FADFFPFK_03458 4.5e-80 ycgB
FADFFPFK_03459 5.6e-256 ycgA S Membrane
FADFFPFK_03460 1.5e-214 amhX S amidohydrolase
FADFFPFK_03461 5.3e-164 opuAC E glycine betaine
FADFFPFK_03462 1.3e-127 opuAB P glycine betaine
FADFFPFK_03463 4.3e-228 proV 3.6.3.32 E glycine betaine
FADFFPFK_03464 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
FADFFPFK_03465 3.3e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
FADFFPFK_03466 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
FADFFPFK_03467 2e-192 yceH P Belongs to the TelA family
FADFFPFK_03468 0.0 yceG S Putative component of 'biosynthetic module'
FADFFPFK_03469 6.3e-137 terC P Protein of unknown function (DUF475)
FADFFPFK_03470 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
FADFFPFK_03471 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
FADFFPFK_03472 1.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
FADFFPFK_03473 2.3e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FADFFPFK_03474 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
FADFFPFK_03475 3.6e-131 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
FADFFPFK_03476 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
FADFFPFK_03477 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
FADFFPFK_03478 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
FADFFPFK_03479 2.1e-173 S response regulator aspartate phosphatase
FADFFPFK_03480 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
FADFFPFK_03481 9.1e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
FADFFPFK_03482 4.2e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
FADFFPFK_03483 6.6e-177 ycdA S Domain of unknown function (DUF5105)
FADFFPFK_03484 5e-173 yccK C Aldo keto reductase
FADFFPFK_03485 3e-199 natB CP ABC-2 family transporter protein
FADFFPFK_03486 4.5e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
FADFFPFK_03487 1.2e-126 lytR_2 T LytTr DNA-binding domain
FADFFPFK_03488 7.3e-151 2.7.13.3 T GHKL domain
FADFFPFK_03489 6.2e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
FADFFPFK_03490 1.7e-58 S RDD family
FADFFPFK_03491 9.3e-102 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
FADFFPFK_03492 2.6e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
FADFFPFK_03493 7e-101 yxaF K Transcriptional regulator
FADFFPFK_03494 7.6e-229 lmrB EGP the major facilitator superfamily
FADFFPFK_03495 7.8e-205 ycbU E Selenocysteine lyase
FADFFPFK_03496 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FADFFPFK_03497 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FADFFPFK_03498 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
FADFFPFK_03499 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
FADFFPFK_03501 1.2e-132 ycbR T vWA found in TerF C terminus
FADFFPFK_03502 2.2e-78 sleB 3.5.1.28 M Cell wall
FADFFPFK_03503 4.1e-52 ycbP S Protein of unknown function (DUF2512)
FADFFPFK_03504 5.1e-114 S ABC-2 family transporter protein
FADFFPFK_03505 4.5e-166 ycbN V ABC transporter, ATP-binding protein
FADFFPFK_03506 2.9e-168 T PhoQ Sensor
FADFFPFK_03507 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FADFFPFK_03508 3e-128 eamA1 EG spore germination
FADFFPFK_03509 2.2e-27 eamA1 EG spore germination
FADFFPFK_03510 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
FADFFPFK_03511 1.6e-171 ycbJ S Macrolide 2'-phosphotransferase
FADFFPFK_03512 4.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
FADFFPFK_03513 2.1e-123 ycbG K FCD
FADFFPFK_03514 1.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
FADFFPFK_03515 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
FADFFPFK_03516 3.4e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FADFFPFK_03517 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
FADFFPFK_03518 2e-169 glnL T Regulator
FADFFPFK_03519 3.6e-228 phoQ 2.7.13.3 T Histidine kinase
FADFFPFK_03520 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
FADFFPFK_03521 9.6e-256 agcS E Sodium alanine symporter
FADFFPFK_03522 1.5e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
FADFFPFK_03523 1.8e-259 mmuP E amino acid
FADFFPFK_03524 2e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
FADFFPFK_03526 4.9e-128 K UTRA
FADFFPFK_03527 5.7e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FADFFPFK_03528 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FADFFPFK_03529 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FADFFPFK_03530 3.9e-192 yceA S Belongs to the UPF0176 family
FADFFPFK_03531 4.6e-45 ybfN
FADFFPFK_03532 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
FADFFPFK_03533 2.7e-85 ybfM S SNARE associated Golgi protein
FADFFPFK_03534 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FADFFPFK_03535 9.7e-166 S Alpha/beta hydrolase family
FADFFPFK_03537 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
FADFFPFK_03538 3.1e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FADFFPFK_03539 2.3e-145 msmR K AraC-like ligand binding domain
FADFFPFK_03541 2.3e-137 ybfH EG EamA-like transporter family
FADFFPFK_03542 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
FADFFPFK_03544 6e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
FADFFPFK_03545 7.4e-169 ybfA 3.4.15.5 K FR47-like protein
FADFFPFK_03546 1.5e-34 S Protein of unknown function (DUF2651)
FADFFPFK_03547 2e-255 glpT G -transporter
FADFFPFK_03548 6.2e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FADFFPFK_03549 3e-290 ybeC E amino acid
FADFFPFK_03550 4.9e-41 ybyB
FADFFPFK_03551 3.5e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
FADFFPFK_03552 1.2e-149 ybxI 3.5.2.6 V beta-lactamase
FADFFPFK_03553 4.9e-30 ybxH S Family of unknown function (DUF5370)
FADFFPFK_03554 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
FADFFPFK_03555 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
FADFFPFK_03556 5.7e-214 ybdO S Domain of unknown function (DUF4885)
FADFFPFK_03557 7.7e-152 ybdN
FADFFPFK_03558 4.4e-138 KLT Protein tyrosine kinase
FADFFPFK_03560 1.1e-170 T His Kinase A (phospho-acceptor) domain
FADFFPFK_03561 1.3e-122 T Transcriptional regulatory protein, C terminal
FADFFPFK_03562 6.9e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FADFFPFK_03563 3.3e-56
FADFFPFK_03564 6.5e-202 ybcL EGP Major facilitator Superfamily
FADFFPFK_03565 5.1e-50 ybzH K Helix-turn-helix domain
FADFFPFK_03566 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
FADFFPFK_03567 8.7e-47
FADFFPFK_03569 4e-90 can 4.2.1.1 P carbonic anhydrase
FADFFPFK_03570 0.0 ybcC S Belongs to the UPF0753 family
FADFFPFK_03571 1.8e-268 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
FADFFPFK_03572 5.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FADFFPFK_03573 2.2e-119 adaA 3.2.2.21 K Transcriptional regulator
FADFFPFK_03574 1.8e-175 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FADFFPFK_03575 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
FADFFPFK_03576 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FADFFPFK_03577 5.7e-224 ybbR S protein conserved in bacteria
FADFFPFK_03578 4.6e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FADFFPFK_03579 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
FADFFPFK_03580 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
FADFFPFK_03586 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
FADFFPFK_03587 1.9e-86 ybbJ J acetyltransferase
FADFFPFK_03588 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FADFFPFK_03589 1.4e-150 ybbH K transcriptional
FADFFPFK_03590 4.9e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FADFFPFK_03591 5.4e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
FADFFPFK_03592 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
FADFFPFK_03593 1.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
FADFFPFK_03594 9.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
FADFFPFK_03595 4e-165 feuA P Iron-uptake system-binding protein
FADFFPFK_03596 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_03597 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_03598 1.4e-141 ybbA S Putative esterase
FADFFPFK_03599 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
FADFFPFK_03600 1.8e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
FADFFPFK_03603 3.8e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FADFFPFK_03604 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
FADFFPFK_03605 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
FADFFPFK_03606 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
FADFFPFK_03607 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FADFFPFK_03608 0.0 ydiF S ABC transporter
FADFFPFK_03609 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
FADFFPFK_03610 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FADFFPFK_03611 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
FADFFPFK_03612 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FADFFPFK_03613 2.9e-27 ydiK S Domain of unknown function (DUF4305)
FADFFPFK_03614 7.9e-129 ydiL S CAAX protease self-immunity
FADFFPFK_03615 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FADFFPFK_03616 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
FADFFPFK_03617 2.9e-150 ydjC S Abhydrolase domain containing 18
FADFFPFK_03618 0.0 K NB-ARC domain
FADFFPFK_03619 2.7e-199 gutB 1.1.1.14 E Dehydrogenase
FADFFPFK_03620 4.8e-252 gutA G MFS/sugar transport protein
FADFFPFK_03621 6.8e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
FADFFPFK_03622 8.7e-114 pspA KT Phage shock protein A
FADFFPFK_03623 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FADFFPFK_03624 3.9e-131 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
FADFFPFK_03625 3.4e-148 ydjI S virion core protein (lumpy skin disease virus)
FADFFPFK_03626 4.7e-196 S Ion transport 2 domain protein
FADFFPFK_03627 1.7e-257 iolT EGP Major facilitator Superfamily
FADFFPFK_03628 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
FADFFPFK_03629 4.5e-64 ydjM M Lytic transglycolase
FADFFPFK_03630 1e-153 ydjN U Involved in the tonB-independent uptake of proteins
FADFFPFK_03632 1.2e-34 ydjO S Cold-inducible protein YdjO
FADFFPFK_03633 3.1e-158 ydjP I Alpha/beta hydrolase family
FADFFPFK_03634 3e-176 yeaA S Protein of unknown function (DUF4003)
FADFFPFK_03635 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
FADFFPFK_03636 9.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
FADFFPFK_03637 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FADFFPFK_03638 7.3e-175 yeaC S COG0714 MoxR-like ATPases
FADFFPFK_03639 8.3e-221 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
FADFFPFK_03640 0.0 yebA E COG1305 Transglutaminase-like enzymes
FADFFPFK_03641 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
FADFFPFK_03642 1e-211 pbuG S permease
FADFFPFK_03643 2.3e-118 yebC M Membrane
FADFFPFK_03645 8.9e-93 yebE S UPF0316 protein
FADFFPFK_03646 8e-28 yebG S NETI protein
FADFFPFK_03647 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FADFFPFK_03648 3.8e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FADFFPFK_03649 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FADFFPFK_03650 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
FADFFPFK_03651 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FADFFPFK_03652 5.6e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FADFFPFK_03653 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FADFFPFK_03654 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FADFFPFK_03655 3.2e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
FADFFPFK_03656 2e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FADFFPFK_03657 5e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
FADFFPFK_03658 7e-234 purD 6.3.4.13 F Belongs to the GARS family
FADFFPFK_03659 5e-72 K helix_turn_helix ASNC type
FADFFPFK_03660 1.6e-225 yjeH E Amino acid permease
FADFFPFK_03661 2.4e-28 S Protein of unknown function (DUF2892)
FADFFPFK_03662 0.0 yerA 3.5.4.2 F adenine deaminase
FADFFPFK_03663 1.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
FADFFPFK_03664 4.8e-51 yerC S protein conserved in bacteria
FADFFPFK_03665 7.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
FADFFPFK_03667 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FADFFPFK_03668 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
FADFFPFK_03669 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FADFFPFK_03670 3e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
FADFFPFK_03671 2.8e-193 yerI S homoserine kinase type II (protein kinase fold)
FADFFPFK_03672 1.6e-123 sapB S MgtC SapB transporter
FADFFPFK_03673 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FADFFPFK_03674 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FADFFPFK_03675 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
FADFFPFK_03676 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FADFFPFK_03677 4.3e-147 yerO K Transcriptional regulator
FADFFPFK_03678 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FADFFPFK_03679 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
FADFFPFK_03680 2.2e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FADFFPFK_03682 7.7e-25
FADFFPFK_03683 2.8e-71 bcgIA 2.1.1.72, 3.1.21.3 L N-6 DNA Methylase
FADFFPFK_03684 3.4e-195 hsdM 2.1.1.72 V HsdM N-terminal domain
FADFFPFK_03685 6.3e-85 3.1.21.3 L Type I restriction modification DNA specificity domain
FADFFPFK_03686 0.0 hsdR 3.1.21.3 L DEAD DEAH box helicase
FADFFPFK_03687 1.2e-56 S Protein of unknown function, DUF600
FADFFPFK_03688 0.0 L nucleic acid phosphodiester bond hydrolysis
FADFFPFK_03690 5.1e-101 L endonuclease activity
FADFFPFK_03691 6.9e-168 3.4.24.40 CO amine dehydrogenase activity
FADFFPFK_03692 5.7e-34
FADFFPFK_03693 7.9e-213 S Tetratricopeptide repeat
FADFFPFK_03695 3e-125 yeeN K transcriptional regulatory protein
FADFFPFK_03697 3e-99 dhaR3 K Transcriptional regulator
FADFFPFK_03698 5.4e-80 yesE S SnoaL-like domain
FADFFPFK_03699 9.9e-144 yesF GM NAD(P)H-binding
FADFFPFK_03700 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
FADFFPFK_03701 1.5e-45 cotJB S CotJB protein
FADFFPFK_03702 5.2e-104 cotJC P Spore Coat
FADFFPFK_03703 6e-102 yesJ K Acetyltransferase (GNAT) family
FADFFPFK_03704 1.8e-102 yesL S Protein of unknown function, DUF624
FADFFPFK_03705 0.0 yesM 2.7.13.3 T Histidine kinase
FADFFPFK_03706 1e-201 yesN K helix_turn_helix, arabinose operon control protein
FADFFPFK_03707 1.6e-246 yesO G Bacterial extracellular solute-binding protein
FADFFPFK_03708 3.1e-170 yesP G Binding-protein-dependent transport system inner membrane component
FADFFPFK_03709 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
FADFFPFK_03710 7.8e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
FADFFPFK_03711 0.0 yesS K Transcriptional regulator
FADFFPFK_03712 2.7e-131 E GDSL-like Lipase/Acylhydrolase
FADFFPFK_03713 3.2e-129 yesU S Domain of unknown function (DUF1961)
FADFFPFK_03714 1e-113 yesV S Protein of unknown function, DUF624
FADFFPFK_03715 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
FADFFPFK_03716 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
FADFFPFK_03717 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
FADFFPFK_03718 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
FADFFPFK_03719 0.0 yetA
FADFFPFK_03720 6.2e-290 lplA G Bacterial extracellular solute-binding protein
FADFFPFK_03721 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
FADFFPFK_03722 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
FADFFPFK_03723 1.3e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
FADFFPFK_03724 6.1e-123 yetF S membrane
FADFFPFK_03725 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
FADFFPFK_03726 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FADFFPFK_03727 2.5e-34
FADFFPFK_03728 8.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FADFFPFK_03729 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
FADFFPFK_03730 2.6e-104 yetJ S Belongs to the BI1 family
FADFFPFK_03731 2.4e-30 yetM CH FAD binding domain
FADFFPFK_03732 3.6e-199 yetN S Protein of unknown function (DUF3900)
FADFFPFK_03733 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
FADFFPFK_03734 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FADFFPFK_03735 3.9e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
FADFFPFK_03736 1.9e-172 yfnG 4.2.1.45 M dehydratase
FADFFPFK_03737 1.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
FADFFPFK_03738 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
FADFFPFK_03739 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
FADFFPFK_03740 1.7e-205 fsr P COG0477 Permeases of the major facilitator superfamily
FADFFPFK_03741 2.5e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
FADFFPFK_03742 1.4e-240 yfnA E amino acid
FADFFPFK_03743 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FADFFPFK_03744 1.1e-113 yfmS NT chemotaxis protein
FADFFPFK_03745 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FADFFPFK_03746 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
FADFFPFK_03747 9e-69 yfmP K transcriptional
FADFFPFK_03748 1.9e-209 yfmO EGP Major facilitator Superfamily
FADFFPFK_03749 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FADFFPFK_03750 1.4e-198 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
FADFFPFK_03751 1e-75 yfmK 2.3.1.128 K acetyltransferase
FADFFPFK_03752 3.6e-188 yfmJ S N-terminal domain of oxidoreductase
FADFFPFK_03753 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
FADFFPFK_03754 3.6e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_03755 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_03756 1.2e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
FADFFPFK_03757 2.6e-24 S Protein of unknown function (DUF3212)
FADFFPFK_03758 7.6e-58 yflT S Heat induced stress protein YflT
FADFFPFK_03759 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
FADFFPFK_03760 1e-233 yflS P Sodium:sulfate symporter transmembrane region
FADFFPFK_03761 2.2e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
FADFFPFK_03762 2.4e-116 citT T response regulator
FADFFPFK_03763 6.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
FADFFPFK_03764 1.9e-226 citM C Citrate transporter
FADFFPFK_03765 2.1e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
FADFFPFK_03766 5.6e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FADFFPFK_03767 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
FADFFPFK_03768 4.9e-122 yflK S protein conserved in bacteria
FADFFPFK_03769 4e-18 yflJ S Protein of unknown function (DUF2639)
FADFFPFK_03770 4.1e-19 yflI
FADFFPFK_03771 5.3e-50 yflH S Protein of unknown function (DUF3243)
FADFFPFK_03772 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
FADFFPFK_03773 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
FADFFPFK_03774 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FADFFPFK_03775 6e-67 yhdN S Domain of unknown function (DUF1992)
FADFFPFK_03776 2.2e-252 agcS_1 E Sodium alanine symporter
FADFFPFK_03777 1.4e-24 yfkQ EG Spore germination protein
FADFFPFK_03778 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FADFFPFK_03779 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
FADFFPFK_03780 1.8e-133 treR K transcriptional
FADFFPFK_03781 1.1e-124 yfkO C nitroreductase
FADFFPFK_03782 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
FADFFPFK_03783 4.7e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
FADFFPFK_03784 1.3e-205 ydiM EGP Major facilitator Superfamily
FADFFPFK_03785 1.3e-28 yfkK S Belongs to the UPF0435 family
FADFFPFK_03786 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FADFFPFK_03787 4.1e-50 yfkI S gas vesicle protein
FADFFPFK_03788 2.2e-143 yihY S Belongs to the UPF0761 family
FADFFPFK_03789 5e-08
FADFFPFK_03790 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
FADFFPFK_03791 6.1e-183 cax P COG0387 Ca2 H antiporter
FADFFPFK_03792 1.2e-146 yfkD S YfkD-like protein
FADFFPFK_03793 6e-149 yfkC M Mechanosensitive ion channel
FADFFPFK_03794 5.4e-222 yfkA S YfkB-like domain
FADFFPFK_03795 1.1e-26 yfjT
FADFFPFK_03796 1.7e-153 pdaA G deacetylase
FADFFPFK_03797 3.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
FADFFPFK_03798 1.7e-184 corA P Mediates influx of magnesium ions
FADFFPFK_03799 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FADFFPFK_03800 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FADFFPFK_03801 5.7e-43 S YfzA-like protein
FADFFPFK_03802 8.1e-190 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FADFFPFK_03803 9.6e-85 yfjM S Psort location Cytoplasmic, score
FADFFPFK_03804 1.3e-29 yfjL
FADFFPFK_03805 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FADFFPFK_03806 1.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FADFFPFK_03807 1.9e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FADFFPFK_03808 2.7e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FADFFPFK_03809 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
FADFFPFK_03810 1.2e-25 sspH S Belongs to the SspH family
FADFFPFK_03811 4e-56 yfjF S UPF0060 membrane protein
FADFFPFK_03812 6.2e-86 S Family of unknown function (DUF5381)
FADFFPFK_03813 4.7e-124 yfjC
FADFFPFK_03814 9.6e-172 yfjB
FADFFPFK_03815 2.6e-44 yfjA S Belongs to the WXG100 family
FADFFPFK_03816 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
FADFFPFK_03817 2.7e-140 glvR K Helix-turn-helix domain, rpiR family
FADFFPFK_03818 2e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FADFFPFK_03819 0.0 yobO M COG5434 Endopolygalacturonase
FADFFPFK_03820 1.4e-306 yfiB3 V ABC transporter
FADFFPFK_03821 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
FADFFPFK_03822 2.2e-64 mhqP S DoxX
FADFFPFK_03823 8.2e-162 yfiE 1.13.11.2 S glyoxalase
FADFFPFK_03825 5.8e-211 yxjM T Histidine kinase
FADFFPFK_03826 1.6e-112 KT LuxR family transcriptional regulator
FADFFPFK_03827 2.4e-167 V ABC transporter, ATP-binding protein
FADFFPFK_03828 6.8e-207 V ABC-2 family transporter protein
FADFFPFK_03829 1.4e-201 V COG0842 ABC-type multidrug transport system, permease component
FADFFPFK_03830 1.8e-93 padR K transcriptional
FADFFPFK_03831 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
FADFFPFK_03832 2.9e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FADFFPFK_03833 2e-109 yfiR K Transcriptional regulator
FADFFPFK_03834 5.3e-218 yfiS EGP Major facilitator Superfamily
FADFFPFK_03835 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
FADFFPFK_03836 1.2e-280 yfiU EGP Major facilitator Superfamily
FADFFPFK_03837 4.9e-79 yfiV K transcriptional
FADFFPFK_03838 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FADFFPFK_03839 5.7e-175 yfiY P ABC transporter substrate-binding protein
FADFFPFK_03840 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_03841 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FADFFPFK_03842 3.9e-167 yfhB 5.3.3.17 S PhzF family
FADFFPFK_03843 8.8e-107 yfhC C nitroreductase
FADFFPFK_03844 2.1e-25 yfhD S YfhD-like protein
FADFFPFK_03846 5.1e-170 yfhF S nucleoside-diphosphate sugar epimerase
FADFFPFK_03847 7.4e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
FADFFPFK_03848 9.7e-52 yfhH S Protein of unknown function (DUF1811)
FADFFPFK_03850 1.1e-209 yfhI EGP Major facilitator Superfamily
FADFFPFK_03851 6.2e-20 sspK S reproduction
FADFFPFK_03852 1.3e-44 yfhJ S WVELL protein
FADFFPFK_03853 7.8e-91 batE T Bacterial SH3 domain homologues
FADFFPFK_03854 1e-47 yfhL S SdpI/YhfL protein family
FADFFPFK_03855 1.3e-170 yfhM S Alpha beta hydrolase
FADFFPFK_03856 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FADFFPFK_03857 0.0 yfhO S Bacterial membrane protein YfhO
FADFFPFK_03858 1.2e-185 yfhP S membrane-bound metal-dependent
FADFFPFK_03859 3.3e-210 mutY L A G-specific
FADFFPFK_03860 6.9e-36 yfhS
FADFFPFK_03861 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FADFFPFK_03862 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
FADFFPFK_03863 1.5e-37 ygaB S YgaB-like protein
FADFFPFK_03864 1.3e-104 ygaC J Belongs to the UPF0374 family
FADFFPFK_03865 1.8e-301 ygaD V ABC transporter
FADFFPFK_03866 3.3e-179 ygaE S Membrane
FADFFPFK_03867 1.7e-243 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
FADFFPFK_03868 2.4e-86 bcp 1.11.1.15 O Peroxiredoxin
FADFFPFK_03869 4e-80 perR P Belongs to the Fur family
FADFFPFK_03870 9.5e-56 ygzB S UPF0295 protein
FADFFPFK_03871 2.5e-166 ygxA S Nucleotidyltransferase-like
FADFFPFK_03872 2.7e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
FADFFPFK_03873 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
FADFFPFK_03874 1.2e-84 gerD
FADFFPFK_03875 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
FADFFPFK_03876 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FADFFPFK_03877 2.8e-65 ybaK S Protein of unknown function (DUF2521)
FADFFPFK_03878 2e-143 ybaJ Q Methyltransferase domain
FADFFPFK_03879 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
FADFFPFK_03880 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FADFFPFK_03881 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
FADFFPFK_03882 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FADFFPFK_03883 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FADFFPFK_03884 2.1e-154 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FADFFPFK_03885 3.6e-58 rplQ J Ribosomal protein L17
FADFFPFK_03886 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FADFFPFK_03887 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FADFFPFK_03888 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FADFFPFK_03889 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
FADFFPFK_03890 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FADFFPFK_03891 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
FADFFPFK_03892 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
FADFFPFK_03893 5.5e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
FADFFPFK_03894 1.8e-72 rplO J binds to the 23S rRNA
FADFFPFK_03895 1.9e-23 rpmD J Ribosomal protein L30
FADFFPFK_03896 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FADFFPFK_03897 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FADFFPFK_03898 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FADFFPFK_03899 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FADFFPFK_03900 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FADFFPFK_03901 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FADFFPFK_03902 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FADFFPFK_03903 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FADFFPFK_03904 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FADFFPFK_03905 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
FADFFPFK_03906 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FADFFPFK_03907 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FADFFPFK_03908 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FADFFPFK_03909 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FADFFPFK_03910 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FADFFPFK_03911 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
FADFFPFK_03912 3e-105 rplD J Forms part of the polypeptide exit tunnel
FADFFPFK_03913 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FADFFPFK_03914 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
FADFFPFK_03915 3.8e-184 ybaC 3.4.11.5 S Alpha/beta hydrolase family
FADFFPFK_03916 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FADFFPFK_03917 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FADFFPFK_03918 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
FADFFPFK_03919 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FADFFPFK_03920 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
FADFFPFK_03921 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FADFFPFK_03922 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FADFFPFK_03923 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
FADFFPFK_03924 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
FADFFPFK_03925 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FADFFPFK_03926 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
FADFFPFK_03927 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FADFFPFK_03928 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
FADFFPFK_03929 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
FADFFPFK_03930 4.4e-115 sigH K Belongs to the sigma-70 factor family
FADFFPFK_03931 1.2e-88 yacP S RNA-binding protein containing a PIN domain
FADFFPFK_03932 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FADFFPFK_03933 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FADFFPFK_03934 2.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
FADFFPFK_03935 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
FADFFPFK_03936 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FADFFPFK_03937 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
FADFFPFK_03938 1.9e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
FADFFPFK_03939 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
FADFFPFK_03940 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FADFFPFK_03941 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FADFFPFK_03942 0.0 clpC O Belongs to the ClpA ClpB family
FADFFPFK_03943 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
FADFFPFK_03944 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
FADFFPFK_03945 2.9e-76 ctsR K Belongs to the CtsR family
FADFFPFK_03946 1.7e-30 csfB S Inhibitor of sigma-G Gin
FADFFPFK_03947 2.9e-100 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
FADFFPFK_03948 2.2e-202 yaaN P Belongs to the TelA family
FADFFPFK_03949 1.5e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
FADFFPFK_03950 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FADFFPFK_03951 2.2e-54 yaaQ S protein conserved in bacteria
FADFFPFK_03952 4.5e-71 yaaR S protein conserved in bacteria
FADFFPFK_03953 1.1e-181 holB 2.7.7.7 L DNA polymerase III
FADFFPFK_03954 6.1e-146 yaaT S stage 0 sporulation protein
FADFFPFK_03955 4.8e-31 yabA L Involved in initiation control of chromosome replication
FADFFPFK_03956 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
FADFFPFK_03957 1.5e-49 yazA L endonuclease containing a URI domain
FADFFPFK_03958 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FADFFPFK_03959 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
FADFFPFK_03960 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FADFFPFK_03961 2e-143 tatD L hydrolase, TatD
FADFFPFK_03962 4.3e-194 rpfB GH23 T protein conserved in bacteria
FADFFPFK_03963 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FADFFPFK_03964 2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
FADFFPFK_03965 1.6e-136 yabG S peptidase
FADFFPFK_03966 7.8e-39 veg S protein conserved in bacteria
FADFFPFK_03967 8.3e-27 sspF S DNA topological change
FADFFPFK_03968 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FADFFPFK_03969 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
FADFFPFK_03970 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
FADFFPFK_03971 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
FADFFPFK_03972 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FADFFPFK_03973 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FADFFPFK_03974 8.7e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FADFFPFK_03975 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
FADFFPFK_03976 2.4e-39 yabK S Peptide ABC transporter permease
FADFFPFK_03977 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FADFFPFK_03978 1.5e-92 spoVT K stage V sporulation protein
FADFFPFK_03979 4.6e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FADFFPFK_03980 3.3e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
FADFFPFK_03981 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
FADFFPFK_03982 1.5e-49 yabP S Sporulation protein YabP
FADFFPFK_03983 2.5e-107 yabQ S spore cortex biosynthesis protein
FADFFPFK_03984 1.1e-44 divIC D Septum formation initiator
FADFFPFK_03985 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
FADFFPFK_03988 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
FADFFPFK_03989 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
FADFFPFK_03990 3.7e-185 KLT serine threonine protein kinase
FADFFPFK_03991 4.2e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
FADFFPFK_03992 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
FADFFPFK_03993 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FADFFPFK_03994 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FADFFPFK_03995 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FADFFPFK_03996 4.4e-135 yacD 5.2.1.8 O peptidyl-prolyl isomerase
FADFFPFK_03997 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FADFFPFK_03998 3.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FADFFPFK_03999 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
FADFFPFK_04000 5.6e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
FADFFPFK_04001 7.7e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FADFFPFK_04002 3.8e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FADFFPFK_04003 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FADFFPFK_04004 4.1e-30 yazB K transcriptional
FADFFPFK_04005 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FADFFPFK_04006 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
FADFFPFK_04007 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
FADFFPFK_04008 7.9e-32 yaaL S Protein of unknown function (DUF2508)
FADFFPFK_04009 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FADFFPFK_04010 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FADFFPFK_04011 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FADFFPFK_04012 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
FADFFPFK_04013 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
FADFFPFK_04014 2.6e-212 yaaH M Glycoside Hydrolase Family
FADFFPFK_04015 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
FADFFPFK_04016 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
FADFFPFK_04017 1.3e-09
FADFFPFK_04018 3.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FADFFPFK_04019 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FADFFPFK_04020 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FADFFPFK_04021 1.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
FADFFPFK_04022 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
FADFFPFK_04023 9.6e-180 yaaC S YaaC-like Protein
FADFFPFK_04024 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FADFFPFK_04025 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)