ORF_ID e_value Gene_name EC_number CAZy COGs Description
HCIEOBLE_00001 3.4e-39 S COG NOG14552 non supervised orthologous group
HCIEOBLE_00002 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIEOBLE_00003 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HCIEOBLE_00004 2.8e-64 yngL S Protein of unknown function (DUF1360)
HCIEOBLE_00005 1.1e-305 yngK T Glycosyl hydrolase-like 10
HCIEOBLE_00007 1.8e-31 S Family of unknown function (DUF5367)
HCIEOBLE_00008 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HCIEOBLE_00009 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCIEOBLE_00010 1.1e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HCIEOBLE_00011 6.6e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HCIEOBLE_00012 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HCIEOBLE_00013 1.3e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HCIEOBLE_00014 1.2e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HCIEOBLE_00015 6.2e-232 nrnB S phosphohydrolase (DHH superfamily)
HCIEOBLE_00016 5.5e-104 yngC S membrane-associated protein
HCIEOBLE_00017 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HCIEOBLE_00018 1.6e-79 yngA S membrane
HCIEOBLE_00019 2.6e-291 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HCIEOBLE_00020 9.1e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HCIEOBLE_00022 4.9e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HCIEOBLE_00023 5.3e-251 agcS E Sodium alanine symporter
HCIEOBLE_00024 3.9e-57 ynfC
HCIEOBLE_00025 2.3e-12
HCIEOBLE_00026 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCIEOBLE_00027 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCIEOBLE_00028 8.6e-69 yccU S CoA-binding protein
HCIEOBLE_00029 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCIEOBLE_00030 4.1e-49 yneR S Belongs to the HesB IscA family
HCIEOBLE_00031 1.3e-53 yneQ
HCIEOBLE_00032 3.5e-73 yneP S Thioesterase-like superfamily
HCIEOBLE_00033 3.9e-35 tlp S Belongs to the Tlp family
HCIEOBLE_00034 3.1e-08 sspN S Small acid-soluble spore protein N family
HCIEOBLE_00036 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HCIEOBLE_00037 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HCIEOBLE_00038 2.2e-14 sspO S Belongs to the SspO family
HCIEOBLE_00039 3.9e-19 sspP S Belongs to the SspP family
HCIEOBLE_00040 5.9e-64 hspX O Spore coat protein
HCIEOBLE_00041 4.2e-74 yneK S Protein of unknown function (DUF2621)
HCIEOBLE_00042 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HCIEOBLE_00043 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HCIEOBLE_00044 7.8e-126 ccdA O cytochrome c biogenesis protein
HCIEOBLE_00045 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HCIEOBLE_00046 1.8e-28 yneF S UPF0154 protein
HCIEOBLE_00047 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HCIEOBLE_00048 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCIEOBLE_00049 4.8e-32 ynzC S UPF0291 protein
HCIEOBLE_00050 5.6e-110 yneB L resolvase
HCIEOBLE_00051 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HCIEOBLE_00052 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCIEOBLE_00053 9.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HCIEOBLE_00054 3.7e-73 yndM S Protein of unknown function (DUF2512)
HCIEOBLE_00055 1.1e-136 yndL S Replication protein
HCIEOBLE_00057 2.7e-307 yndJ S YndJ-like protein
HCIEOBLE_00058 1.3e-113 yndH S Domain of unknown function (DUF4166)
HCIEOBLE_00059 7.5e-149 yndG S DoxX-like family
HCIEOBLE_00060 6.9e-215 gerLC S Spore germination protein
HCIEOBLE_00061 1.6e-194 gerAB U Spore germination
HCIEOBLE_00062 3.2e-281 gerAA EG Spore germination protein
HCIEOBLE_00065 1.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HCIEOBLE_00066 1.8e-71
HCIEOBLE_00067 7.9e-25 tatA U protein secretion
HCIEOBLE_00070 1.2e-127 S Domain of unknown function, YrpD
HCIEOBLE_00072 8.6e-164 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCIEOBLE_00075 5.2e-15
HCIEOBLE_00076 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HCIEOBLE_00077 5e-81 yncE S Protein of unknown function (DUF2691)
HCIEOBLE_00078 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCIEOBLE_00079 4.7e-255 iolT EGP Major facilitator Superfamily
HCIEOBLE_00080 1.4e-110 yokF 3.1.31.1 L RNA catabolic process
HCIEOBLE_00081 1.5e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HCIEOBLE_00082 3.7e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HCIEOBLE_00083 1.8e-212 xylR GK ROK family
HCIEOBLE_00084 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HCIEOBLE_00085 8.7e-254 xynT G MFS/sugar transport protein
HCIEOBLE_00086 5.5e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HCIEOBLE_00089 2.9e-77 S CAAX protease self-immunity
HCIEOBLE_00091 4.4e-97 ynaD J Acetyltransferase (GNAT) domain
HCIEOBLE_00092 1.2e-141 ynaC
HCIEOBLE_00093 8.9e-90 G SMI1-KNR4 cell-wall
HCIEOBLE_00094 3.7e-38
HCIEOBLE_00095 6e-31
HCIEOBLE_00096 3.8e-10
HCIEOBLE_00097 7e-261 glnA 6.3.1.2 E glutamine synthetase
HCIEOBLE_00098 1.1e-68 glnR K transcriptional
HCIEOBLE_00099 6.3e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HCIEOBLE_00100 3.9e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCIEOBLE_00101 8.7e-69 spoVK O stage V sporulation protein K
HCIEOBLE_00102 1.2e-244 cisA2 L Recombinase
HCIEOBLE_00104 2.2e-92 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCIEOBLE_00113 2.5e-30 sspB S spore protein
HCIEOBLE_00115 8.4e-50
HCIEOBLE_00118 6.1e-65
HCIEOBLE_00119 1.1e-161 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCIEOBLE_00123 2.2e-15 vanZ V COG4767 Glycopeptide antibiotics resistance protein
HCIEOBLE_00124 2.5e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HCIEOBLE_00126 9.4e-34 O Glutaredoxin
HCIEOBLE_00127 3.8e-63 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCIEOBLE_00128 8.4e-93 L HNH endonuclease
HCIEOBLE_00129 8.5e-105 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCIEOBLE_00131 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCIEOBLE_00132 3.4e-62 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HCIEOBLE_00144 2.8e-22 S hydrolase activity
HCIEOBLE_00153 6e-80 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
HCIEOBLE_00158 2e-56 DR0488 S protein conserved in bacteria
HCIEOBLE_00159 2.5e-39 DR0488 S protein conserved in bacteria
HCIEOBLE_00160 0.0 S Bacterial DNA polymerase III alpha subunit
HCIEOBLE_00161 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HCIEOBLE_00162 2.9e-223 L DNA primase activity
HCIEOBLE_00163 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
HCIEOBLE_00164 5.3e-86
HCIEOBLE_00165 7.6e-180 L AAA domain
HCIEOBLE_00166 1.5e-169
HCIEOBLE_00168 1.5e-79
HCIEOBLE_00171 3.6e-26
HCIEOBLE_00173 3.6e-128 yoqW S Belongs to the SOS response-associated peptidase family
HCIEOBLE_00174 3e-145 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HCIEOBLE_00177 6e-42
HCIEOBLE_00180 1.4e-09 S YopX protein
HCIEOBLE_00182 1.7e-08 S YopX protein
HCIEOBLE_00183 2.4e-92 S Protein of unknown function (DUF1273)
HCIEOBLE_00190 3.2e-10 S YopX protein
HCIEOBLE_00195 1.1e-33 K Transcriptional regulator
HCIEOBLE_00196 2.7e-177
HCIEOBLE_00197 1.6e-260 S DNA-sulfur modification-associated
HCIEOBLE_00198 4.4e-197 L Belongs to the 'phage' integrase family
HCIEOBLE_00203 6.6e-106
HCIEOBLE_00204 2.5e-18 coaE 2.7.1.24, 2.7.7.87 H dephospho-CoA kinase activity
HCIEOBLE_00205 3.6e-23
HCIEOBLE_00206 1.1e-79 J tRNA cytidylyltransferase activity
HCIEOBLE_00211 1e-79 K Divergent AAA domain
HCIEOBLE_00213 2.6e-72
HCIEOBLE_00215 1.4e-31 K Cro/C1-type HTH DNA-binding domain
HCIEOBLE_00224 2.7e-198 3.1.21.3 L Domain of unknown function (DUF4942)
HCIEOBLE_00226 1.1e-204
HCIEOBLE_00227 3.5e-96
HCIEOBLE_00230 0.0 S RNA-directed RNA polymerase activity
HCIEOBLE_00231 1.5e-14 L GIY-YIG type nucleases (URI domain)
HCIEOBLE_00232 7e-110
HCIEOBLE_00233 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCIEOBLE_00235 5.6e-201 S Calcineurin-like phosphoesterase superfamily domain
HCIEOBLE_00238 7e-175
HCIEOBLE_00239 0.0 gp17a S Terminase-like family
HCIEOBLE_00240 3e-276
HCIEOBLE_00241 7.6e-261
HCIEOBLE_00242 1.3e-93
HCIEOBLE_00243 1.6e-185
HCIEOBLE_00244 1.1e-80
HCIEOBLE_00245 5.1e-66
HCIEOBLE_00247 9.2e-121
HCIEOBLE_00248 1.7e-90
HCIEOBLE_00249 8.1e-131
HCIEOBLE_00250 1e-89
HCIEOBLE_00253 6.1e-50
HCIEOBLE_00254 2e-41
HCIEOBLE_00255 1.6e-07
HCIEOBLE_00257 5.2e-84
HCIEOBLE_00258 2.3e-64
HCIEOBLE_00259 5.2e-123 xerH L Belongs to the 'phage' integrase family
HCIEOBLE_00261 4.6e-107
HCIEOBLE_00262 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HCIEOBLE_00263 3.2e-85 S Phage tail protein
HCIEOBLE_00264 3.3e-294 S Pfam Transposase IS66
HCIEOBLE_00265 2.1e-101
HCIEOBLE_00266 7.6e-65 S outer membrane
HCIEOBLE_00267 4.5e-77 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HCIEOBLE_00269 2.7e-36 S Bacteriophage holin
HCIEOBLE_00270 1.1e-203 S aspartate phosphatase
HCIEOBLE_00272 3.2e-231 S impB/mucB/samB family C-terminal domain
HCIEOBLE_00273 1.5e-50 S YolD-like protein
HCIEOBLE_00275 6e-38
HCIEOBLE_00276 6.8e-93 yokK S SMI1 / KNR4 family
HCIEOBLE_00277 9.1e-216 UW nuclease activity
HCIEOBLE_00278 1.8e-131 V HNH endonuclease
HCIEOBLE_00279 6.2e-67 G SMI1-KNR4 cell-wall
HCIEOBLE_00280 1.7e-35
HCIEOBLE_00281 2.3e-106 yokF 3.1.31.1 L RNA catabolic process
HCIEOBLE_00282 5.8e-81 yhbS S family acetyltransferase
HCIEOBLE_00284 2.4e-97 spoVK O stage V sporulation protein K
HCIEOBLE_00285 6.7e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCIEOBLE_00286 6.5e-108 ymaB
HCIEOBLE_00287 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCIEOBLE_00288 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCIEOBLE_00289 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HCIEOBLE_00290 4.5e-22 ymzA
HCIEOBLE_00291 8.2e-23
HCIEOBLE_00292 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HCIEOBLE_00293 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCIEOBLE_00294 2.1e-46 ymaF S YmaF family
HCIEOBLE_00296 5.4e-50 ebrA P Small Multidrug Resistance protein
HCIEOBLE_00297 4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HCIEOBLE_00298 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
HCIEOBLE_00299 2.1e-126 ymaC S Replication protein
HCIEOBLE_00300 1.9e-07 K Transcriptional regulator
HCIEOBLE_00301 2.3e-251 aprX O Belongs to the peptidase S8 family
HCIEOBLE_00302 2.3e-161 ymaE S Metallo-beta-lactamase superfamily
HCIEOBLE_00303 4.4e-61 ymzB
HCIEOBLE_00304 4.1e-231 cypA C Cytochrome P450
HCIEOBLE_00305 0.0 pks13 HQ Beta-ketoacyl synthase
HCIEOBLE_00306 0.0 dhbF IQ polyketide synthase
HCIEOBLE_00307 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HCIEOBLE_00308 0.0 pfaA Q Polyketide synthase of type I
HCIEOBLE_00309 0.0 rhiB IQ polyketide synthase
HCIEOBLE_00310 1.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HCIEOBLE_00311 9.4e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
HCIEOBLE_00312 1.5e-244 pksG 2.3.3.10 I synthase
HCIEOBLE_00313 6.6e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCIEOBLE_00314 1.4e-37 acpK IQ Phosphopantetheine attachment site
HCIEOBLE_00315 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HCIEOBLE_00316 3.9e-184 pksD Q Acyl transferase domain
HCIEOBLE_00318 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HCIEOBLE_00319 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HCIEOBLE_00320 4.4e-109 pksA K Transcriptional regulator
HCIEOBLE_00321 1e-96 ymcC S Membrane
HCIEOBLE_00322 4.1e-67 S Regulatory protein YrvL
HCIEOBLE_00324 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCIEOBLE_00325 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCIEOBLE_00326 2.2e-88 cotE S Spore coat protein
HCIEOBLE_00327 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HCIEOBLE_00328 1.1e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HCIEOBLE_00329 2.5e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HCIEOBLE_00330 1.5e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HCIEOBLE_00331 1.2e-36 spoVS S Stage V sporulation protein S
HCIEOBLE_00332 1.9e-152 ymdB S protein conserved in bacteria
HCIEOBLE_00333 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HCIEOBLE_00334 8.8e-215 pbpX V Beta-lactamase
HCIEOBLE_00335 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCIEOBLE_00336 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
HCIEOBLE_00337 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCIEOBLE_00338 1.9e-124 ymfM S protein conserved in bacteria
HCIEOBLE_00339 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HCIEOBLE_00340 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HCIEOBLE_00341 6.6e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HCIEOBLE_00342 1.4e-242 ymfH S zinc protease
HCIEOBLE_00343 7e-234 ymfF S Peptidase M16
HCIEOBLE_00344 3.8e-205 ymfD EGP Major facilitator Superfamily
HCIEOBLE_00345 1.4e-133 ymfC K Transcriptional regulator
HCIEOBLE_00346 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HCIEOBLE_00347 2.9e-31 S YlzJ-like protein
HCIEOBLE_00348 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HCIEOBLE_00349 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCIEOBLE_00350 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCIEOBLE_00351 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HCIEOBLE_00352 4.1e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCIEOBLE_00353 4.8e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HCIEOBLE_00354 3.8e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HCIEOBLE_00355 2.6e-42 ymxH S YlmC YmxH family
HCIEOBLE_00356 4.4e-233 pepR S Belongs to the peptidase M16 family
HCIEOBLE_00357 2.4e-178 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HCIEOBLE_00358 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HCIEOBLE_00359 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCIEOBLE_00360 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HCIEOBLE_00361 5.6e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCIEOBLE_00362 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCIEOBLE_00363 3e-44 ylxP S protein conserved in bacteria
HCIEOBLE_00364 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCIEOBLE_00365 3.1e-47 ylxQ J ribosomal protein
HCIEOBLE_00366 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HCIEOBLE_00367 1.1e-203 nusA K Participates in both transcription termination and antitermination
HCIEOBLE_00368 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HCIEOBLE_00369 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCIEOBLE_00370 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCIEOBLE_00371 1.3e-232 rasP M zinc metalloprotease
HCIEOBLE_00372 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HCIEOBLE_00373 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HCIEOBLE_00374 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCIEOBLE_00375 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCIEOBLE_00376 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HCIEOBLE_00377 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCIEOBLE_00378 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HCIEOBLE_00379 3.1e-76 ylxL
HCIEOBLE_00380 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEOBLE_00381 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HCIEOBLE_00382 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HCIEOBLE_00383 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HCIEOBLE_00384 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HCIEOBLE_00385 2.9e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HCIEOBLE_00386 7.5e-158 flhG D Belongs to the ParA family
HCIEOBLE_00387 1.2e-197 flhF N Flagellar biosynthesis regulator FlhF
HCIEOBLE_00388 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HCIEOBLE_00389 6.9e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HCIEOBLE_00390 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HCIEOBLE_00391 2.2e-36 fliQ N Role in flagellar biosynthesis
HCIEOBLE_00392 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HCIEOBLE_00393 5.1e-95 fliZ N Flagellar biosynthesis protein, FliO
HCIEOBLE_00394 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HCIEOBLE_00395 6.6e-183 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HCIEOBLE_00396 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HCIEOBLE_00397 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HCIEOBLE_00398 2.4e-139 flgG N Flagellar basal body rod
HCIEOBLE_00399 2.3e-72 flgD N Flagellar basal body rod modification protein
HCIEOBLE_00400 9.2e-214 fliK N Flagellar hook-length control protein
HCIEOBLE_00401 3.8e-36 ylxF S MgtE intracellular N domain
HCIEOBLE_00402 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HCIEOBLE_00403 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HCIEOBLE_00404 5.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HCIEOBLE_00405 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HCIEOBLE_00406 2.6e-254 fliF N The M ring may be actively involved in energy transduction
HCIEOBLE_00407 1.9e-31 fliE N Flagellar hook-basal body
HCIEOBLE_00408 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
HCIEOBLE_00409 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HCIEOBLE_00410 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HCIEOBLE_00411 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCIEOBLE_00412 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCIEOBLE_00413 2.5e-169 xerC L tyrosine recombinase XerC
HCIEOBLE_00414 2.8e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HCIEOBLE_00415 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCIEOBLE_00416 4e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HCIEOBLE_00417 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HCIEOBLE_00418 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HCIEOBLE_00419 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HCIEOBLE_00420 5.5e-290 ylqG
HCIEOBLE_00421 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCIEOBLE_00422 3.5e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCIEOBLE_00423 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCIEOBLE_00424 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HCIEOBLE_00425 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCIEOBLE_00426 1.4e-60 ylqD S YlqD protein
HCIEOBLE_00427 4.5e-36 ylqC S Belongs to the UPF0109 family
HCIEOBLE_00428 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HCIEOBLE_00429 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCIEOBLE_00430 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCIEOBLE_00431 2.9e-87
HCIEOBLE_00432 4.4e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCIEOBLE_00433 0.0 smc D Required for chromosome condensation and partitioning
HCIEOBLE_00434 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCIEOBLE_00435 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCIEOBLE_00436 6.1e-129 IQ reductase
HCIEOBLE_00437 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HCIEOBLE_00438 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCIEOBLE_00439 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HCIEOBLE_00440 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCIEOBLE_00441 1.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
HCIEOBLE_00442 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HCIEOBLE_00443 2.6e-297 yloV S kinase related to dihydroxyacetone kinase
HCIEOBLE_00444 5.5e-59 asp S protein conserved in bacteria
HCIEOBLE_00445 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HCIEOBLE_00446 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HCIEOBLE_00447 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HCIEOBLE_00448 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCIEOBLE_00449 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HCIEOBLE_00450 2.7e-140 stp 3.1.3.16 T phosphatase
HCIEOBLE_00451 2e-205 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HCIEOBLE_00452 4.6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCIEOBLE_00453 4.2e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCIEOBLE_00454 3.3e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCIEOBLE_00455 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCIEOBLE_00456 4.1e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCIEOBLE_00457 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCIEOBLE_00458 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HCIEOBLE_00459 1.5e-40 ylzA S Belongs to the UPF0296 family
HCIEOBLE_00460 2.4e-156 yloC S stress-induced protein
HCIEOBLE_00461 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HCIEOBLE_00462 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HCIEOBLE_00463 2.4e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HCIEOBLE_00464 1.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HCIEOBLE_00465 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HCIEOBLE_00466 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HCIEOBLE_00467 6.5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HCIEOBLE_00468 5.9e-178 cysP P phosphate transporter
HCIEOBLE_00469 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HCIEOBLE_00471 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCIEOBLE_00472 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCIEOBLE_00473 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCIEOBLE_00474 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HCIEOBLE_00475 0.0 carB 6.3.5.5 F Belongs to the CarB family
HCIEOBLE_00476 4.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCIEOBLE_00477 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCIEOBLE_00478 7.2e-164 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HCIEOBLE_00479 5.8e-231 pyrP F Xanthine uracil
HCIEOBLE_00480 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCIEOBLE_00481 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCIEOBLE_00482 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCIEOBLE_00483 1.3e-63 dksA T COG1734 DnaK suppressor protein
HCIEOBLE_00484 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCIEOBLE_00485 2.6e-67 divIVA D Cell division initiation protein
HCIEOBLE_00486 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HCIEOBLE_00487 1.6e-39 yggT S membrane
HCIEOBLE_00488 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCIEOBLE_00489 1.1e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HCIEOBLE_00490 2.4e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HCIEOBLE_00491 2.4e-37 ylmC S sporulation protein
HCIEOBLE_00492 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
HCIEOBLE_00493 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HCIEOBLE_00494 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEOBLE_00495 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEOBLE_00496 2.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HCIEOBLE_00497 0.0 bpr O COG1404 Subtilisin-like serine proteases
HCIEOBLE_00498 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCIEOBLE_00499 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCIEOBLE_00500 6.2e-58 sbp S small basic protein
HCIEOBLE_00501 1e-102 ylxX S protein conserved in bacteria
HCIEOBLE_00502 4.1e-103 ylxW S protein conserved in bacteria
HCIEOBLE_00503 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCIEOBLE_00504 5.3e-167 murB 1.3.1.98 M cell wall formation
HCIEOBLE_00505 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCIEOBLE_00506 5.7e-186 spoVE D Belongs to the SEDS family
HCIEOBLE_00507 5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCIEOBLE_00508 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCIEOBLE_00509 3.4e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCIEOBLE_00510 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HCIEOBLE_00511 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HCIEOBLE_00512 3.7e-44 ftsL D Essential cell division protein
HCIEOBLE_00513 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCIEOBLE_00514 2.9e-78 mraZ K Belongs to the MraZ family
HCIEOBLE_00515 1.8e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HCIEOBLE_00516 6.8e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCIEOBLE_00517 4e-89 ylbP K n-acetyltransferase
HCIEOBLE_00518 7.5e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HCIEOBLE_00519 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HCIEOBLE_00520 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HCIEOBLE_00522 2.8e-235 ylbM S Belongs to the UPF0348 family
HCIEOBLE_00523 2.6e-186 ylbL T Belongs to the peptidase S16 family
HCIEOBLE_00524 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
HCIEOBLE_00525 1.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
HCIEOBLE_00526 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCIEOBLE_00527 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
HCIEOBLE_00528 7.5e-39 ylbG S UPF0298 protein
HCIEOBLE_00529 1.8e-75 ylbF S Belongs to the UPF0342 family
HCIEOBLE_00530 6.7e-37 ylbE S YlbE-like protein
HCIEOBLE_00531 3.4e-62 ylbD S Putative coat protein
HCIEOBLE_00532 8.1e-199 ylbC S protein with SCP PR1 domains
HCIEOBLE_00533 2.6e-74 ylbB T COG0517 FOG CBS domain
HCIEOBLE_00534 7e-62 ylbA S YugN-like family
HCIEOBLE_00535 4.4e-166 ctaG S cytochrome c oxidase
HCIEOBLE_00536 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HCIEOBLE_00537 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HCIEOBLE_00538 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HCIEOBLE_00539 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HCIEOBLE_00540 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HCIEOBLE_00541 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HCIEOBLE_00542 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HCIEOBLE_00543 2.7e-211 ftsW D Belongs to the SEDS family
HCIEOBLE_00544 8.7e-44 ylaN S Belongs to the UPF0358 family
HCIEOBLE_00545 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HCIEOBLE_00546 2.3e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HCIEOBLE_00547 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HCIEOBLE_00548 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCIEOBLE_00549 2.5e-32 ylaI S protein conserved in bacteria
HCIEOBLE_00550 1.6e-46 ylaH S YlaH-like protein
HCIEOBLE_00551 0.0 typA T GTP-binding protein TypA
HCIEOBLE_00552 8.2e-22 S Family of unknown function (DUF5325)
HCIEOBLE_00553 5.9e-37 ylaE
HCIEOBLE_00554 9.1e-12 sigC S Putative zinc-finger
HCIEOBLE_00555 5.6e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HCIEOBLE_00556 3e-41 ylaB
HCIEOBLE_00557 0.0 ylaA
HCIEOBLE_00558 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HCIEOBLE_00559 3e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HCIEOBLE_00560 2e-77 ykzC S Acetyltransferase (GNAT) family
HCIEOBLE_00561 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
HCIEOBLE_00562 7.1e-26 ykzI
HCIEOBLE_00563 6e-117 yktB S Belongs to the UPF0637 family
HCIEOBLE_00564 5.9e-42 yktA S Belongs to the UPF0223 family
HCIEOBLE_00565 1e-276 speA 4.1.1.19 E Arginine
HCIEOBLE_00566 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HCIEOBLE_00567 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCIEOBLE_00568 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCIEOBLE_00569 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCIEOBLE_00570 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCIEOBLE_00571 1e-114 recN L Putative cell-wall binding lipoprotein
HCIEOBLE_00573 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCIEOBLE_00574 5.5e-147 ykrA S hydrolases of the HAD superfamily
HCIEOBLE_00575 8.2e-31 ykzG S Belongs to the UPF0356 family
HCIEOBLE_00576 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCIEOBLE_00577 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HCIEOBLE_00578 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HCIEOBLE_00579 6.5e-156 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HCIEOBLE_00580 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HCIEOBLE_00581 1.5e-43 abrB K of stationary sporulation gene expression
HCIEOBLE_00582 7.7e-183 mreB D Rod-share determining protein MreBH
HCIEOBLE_00583 1.1e-12 S Uncharacterized protein YkpC
HCIEOBLE_00584 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HCIEOBLE_00585 7.6e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCIEOBLE_00586 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HCIEOBLE_00587 8.1e-39 ykoA
HCIEOBLE_00588 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HCIEOBLE_00589 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HCIEOBLE_00590 6.9e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HCIEOBLE_00591 3.1e-136 fruR K Transcriptional regulator
HCIEOBLE_00592 1.8e-207 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HCIEOBLE_00593 3.6e-123 macB V ABC transporter, ATP-binding protein
HCIEOBLE_00594 1.2e-157 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCIEOBLE_00595 4.7e-115 yknW S Yip1 domain
HCIEOBLE_00596 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCIEOBLE_00597 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCIEOBLE_00598 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HCIEOBLE_00599 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HCIEOBLE_00600 1.4e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HCIEOBLE_00601 1.9e-242 moeA 2.10.1.1 H molybdopterin
HCIEOBLE_00602 1.4e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HCIEOBLE_00603 4.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HCIEOBLE_00604 9.3e-146 yknT
HCIEOBLE_00605 5.8e-95 rok K Repressor of ComK
HCIEOBLE_00606 2e-79 ykuV CO thiol-disulfide
HCIEOBLE_00607 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HCIEOBLE_00608 6.9e-119 ykuT M Mechanosensitive ion channel
HCIEOBLE_00609 9e-37 ykuS S Belongs to the UPF0180 family
HCIEOBLE_00610 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCIEOBLE_00611 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCIEOBLE_00612 6.7e-78 fld C Flavodoxin
HCIEOBLE_00613 2.6e-174 ykuO
HCIEOBLE_00614 1.7e-84 fld C Flavodoxin domain
HCIEOBLE_00615 3.5e-168 ccpC K Transcriptional regulator
HCIEOBLE_00616 1.6e-76 ykuL S CBS domain
HCIEOBLE_00617 3.9e-27 ykzF S Antirepressor AbbA
HCIEOBLE_00618 4.4e-94 ykuK S Ribonuclease H-like
HCIEOBLE_00619 3.9e-37 ykuJ S protein conserved in bacteria
HCIEOBLE_00620 1.3e-232 ykuI T Diguanylate phosphodiesterase
HCIEOBLE_00621 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEOBLE_00622 9.4e-166 ykuE S Metallophosphoesterase
HCIEOBLE_00623 1.8e-87 ykuD S protein conserved in bacteria
HCIEOBLE_00624 2.8e-238 ykuC EGP Major facilitator Superfamily
HCIEOBLE_00625 4.9e-84 ykyB S YkyB-like protein
HCIEOBLE_00626 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HCIEOBLE_00627 3.7e-15
HCIEOBLE_00628 6.3e-221 patA 2.6.1.1 E Aminotransferase
HCIEOBLE_00629 0.0 pilS 2.7.13.3 T Histidine kinase
HCIEOBLE_00630 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HCIEOBLE_00631 1.8e-123 ykwD J protein with SCP PR1 domains
HCIEOBLE_00632 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HCIEOBLE_00633 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HCIEOBLE_00634 2.6e-256 mcpC NT chemotaxis protein
HCIEOBLE_00635 7.6e-109 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCIEOBLE_00636 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
HCIEOBLE_00637 2.1e-38 splA S Transcriptional regulator
HCIEOBLE_00638 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCIEOBLE_00639 2.1e-39 ptsH G phosphocarrier protein HPr
HCIEOBLE_00640 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCIEOBLE_00641 7.6e-128 glcT K antiterminator
HCIEOBLE_00642 5.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
HCIEOBLE_00644 9.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HCIEOBLE_00645 2.3e-09
HCIEOBLE_00646 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HCIEOBLE_00647 4.9e-90 stoA CO thiol-disulfide
HCIEOBLE_00648 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCIEOBLE_00649 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
HCIEOBLE_00650 2.8e-28
HCIEOBLE_00651 6e-25 ykvS S protein conserved in bacteria
HCIEOBLE_00652 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HCIEOBLE_00653 5.3e-162 G Glycosyl hydrolases family 18
HCIEOBLE_00654 1.7e-34 3.5.1.104 M LysM domain
HCIEOBLE_00655 2.4e-214 ykvP 3.5.1.28 M Glycosyl transferases group 1
HCIEOBLE_00656 7e-133 IQ Enoyl-(Acyl carrier protein) reductase
HCIEOBLE_00657 7.6e-61 ykvN K HxlR-like helix-turn-helix
HCIEOBLE_00658 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HCIEOBLE_00659 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HCIEOBLE_00660 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HCIEOBLE_00661 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HCIEOBLE_00662 3.3e-181 ykvI S membrane
HCIEOBLE_00663 0.0 clpE O Belongs to the ClpA ClpB family
HCIEOBLE_00664 1e-137 motA N flagellar motor
HCIEOBLE_00665 2.5e-125 motB N Flagellar motor protein
HCIEOBLE_00666 1.3e-75 ykvE K transcriptional
HCIEOBLE_00667 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HCIEOBLE_00668 7.5e-63 eag
HCIEOBLE_00669 6.4e-09 S Spo0E like sporulation regulatory protein
HCIEOBLE_00670 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HCIEOBLE_00671 5.4e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HCIEOBLE_00672 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HCIEOBLE_00673 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HCIEOBLE_00674 1e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HCIEOBLE_00675 3.1e-231 mtnE 2.6.1.83 E Aminotransferase
HCIEOBLE_00676 1.7e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HCIEOBLE_00677 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HCIEOBLE_00678 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HCIEOBLE_00680 2e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCIEOBLE_00681 0.0 kinE 2.7.13.3 T Histidine kinase
HCIEOBLE_00682 1.4e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HCIEOBLE_00683 4.5e-22 ykzE
HCIEOBLE_00684 1.2e-10 ydfR S Protein of unknown function (DUF421)
HCIEOBLE_00685 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HCIEOBLE_00686 3.5e-155 htpX O Belongs to the peptidase M48B family
HCIEOBLE_00687 5.6e-124 ykrK S Domain of unknown function (DUF1836)
HCIEOBLE_00688 1.9e-26 sspD S small acid-soluble spore protein
HCIEOBLE_00689 1e-114 rsgI S Anti-sigma factor N-terminus
HCIEOBLE_00690 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEOBLE_00691 3e-176 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HCIEOBLE_00692 5.4e-110 ykoX S membrane-associated protein
HCIEOBLE_00693 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HCIEOBLE_00694 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HCIEOBLE_00695 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HCIEOBLE_00696 6.2e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCIEOBLE_00697 0.0 ykoS
HCIEOBLE_00698 1.7e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HCIEOBLE_00699 1.1e-98 ykoP G polysaccharide deacetylase
HCIEOBLE_00700 1.3e-209 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HCIEOBLE_00701 1.3e-81 mhqR K transcriptional
HCIEOBLE_00702 6.9e-26 ykoL
HCIEOBLE_00703 5.9e-18
HCIEOBLE_00704 1.4e-53 tnrA K transcriptional
HCIEOBLE_00705 2.2e-222 mgtE P Acts as a magnesium transporter
HCIEOBLE_00708 1.1e-84 ykoJ S Peptidase propeptide and YPEB domain
HCIEOBLE_00709 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
HCIEOBLE_00710 2.8e-241 ykoH 2.7.13.3 T Histidine kinase
HCIEOBLE_00711 4.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_00712 1.9e-109 ykoF S YKOF-related Family
HCIEOBLE_00713 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
HCIEOBLE_00714 2.4e-303 P ABC transporter, ATP-binding protein
HCIEOBLE_00715 2.4e-136 ykoC P Cobalt transport protein
HCIEOBLE_00716 1.8e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HCIEOBLE_00717 2.5e-175 isp O Belongs to the peptidase S8 family
HCIEOBLE_00718 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HCIEOBLE_00719 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HCIEOBLE_00720 8.4e-72 ohrB O Organic hydroperoxide resistance protein
HCIEOBLE_00721 4.4e-74 ohrR K COG1846 Transcriptional regulators
HCIEOBLE_00722 4.8e-70 ohrA O Organic hydroperoxide resistance protein
HCIEOBLE_00723 7.6e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCIEOBLE_00724 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCIEOBLE_00725 8.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HCIEOBLE_00726 1.6e-49 ykkD P Multidrug resistance protein
HCIEOBLE_00727 1e-54 ykkC P Multidrug resistance protein
HCIEOBLE_00728 9.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HCIEOBLE_00729 2.6e-97 ykkA S Protein of unknown function (DUF664)
HCIEOBLE_00730 3.9e-128 ykjA S Protein of unknown function (DUF421)
HCIEOBLE_00731 1.5e-09
HCIEOBLE_00732 1.2e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HCIEOBLE_00733 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HCIEOBLE_00734 6.5e-159 ykgA E Amidinotransferase
HCIEOBLE_00735 1.1e-200 pgl 3.1.1.31 G 6-phosphogluconolactonase
HCIEOBLE_00736 5e-187 ykfD E Belongs to the ABC transporter superfamily
HCIEOBLE_00737 7.7e-171 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HCIEOBLE_00738 4.8e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HCIEOBLE_00739 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HCIEOBLE_00741 0.0 dppE E ABC transporter substrate-binding protein
HCIEOBLE_00742 9.3e-189 dppD P Belongs to the ABC transporter superfamily
HCIEOBLE_00743 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEOBLE_00744 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEOBLE_00745 5.1e-153 dppA E D-aminopeptidase
HCIEOBLE_00746 1.6e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HCIEOBLE_00747 8.3e-209 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCIEOBLE_00749 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCIEOBLE_00750 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCIEOBLE_00751 1.4e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HCIEOBLE_00752 1.2e-241 steT E amino acid
HCIEOBLE_00753 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HCIEOBLE_00754 5.8e-175 pit P phosphate transporter
HCIEOBLE_00755 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HCIEOBLE_00756 6.7e-23 spoIISB S Stage II sporulation protein SB
HCIEOBLE_00757 3.8e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCIEOBLE_00758 9.3e-40 xhlB S SPP1 phage holin
HCIEOBLE_00759 2.8e-39 xhlA S Haemolysin XhlA
HCIEOBLE_00760 8.1e-154 xepA
HCIEOBLE_00761 5.5e-22 xkdX
HCIEOBLE_00762 1.6e-44 xkdW S XkdW protein
HCIEOBLE_00763 0.0
HCIEOBLE_00764 8.7e-41
HCIEOBLE_00765 7.6e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HCIEOBLE_00766 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HCIEOBLE_00767 8.2e-70 xkdS S Protein of unknown function (DUF2634)
HCIEOBLE_00768 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HCIEOBLE_00769 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HCIEOBLE_00770 1.4e-121 xkdP S Lysin motif
HCIEOBLE_00771 0.0 xkdO L Transglycosylase SLT domain
HCIEOBLE_00772 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
HCIEOBLE_00773 1e-75 xkdM S Phage tail tube protein
HCIEOBLE_00774 9.3e-256 xkdK S Phage tail sheath C-terminal domain
HCIEOBLE_00775 1.9e-77 xkdJ
HCIEOBLE_00776 2.9e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
HCIEOBLE_00777 1.6e-63 yqbH S Domain of unknown function (DUF3599)
HCIEOBLE_00778 2.8e-61 yqbG S Protein of unknown function (DUF3199)
HCIEOBLE_00779 1.7e-168 xkdG S Phage capsid family
HCIEOBLE_00780 2.9e-132 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HCIEOBLE_00781 1.6e-285 yqbA S portal protein
HCIEOBLE_00782 1.5e-252 xtmB S phage terminase, large subunit
HCIEOBLE_00783 5.3e-139 xtmA L phage terminase small subunit
HCIEOBLE_00784 3.5e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HCIEOBLE_00785 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HCIEOBLE_00788 4.1e-118 xkdC L Bacterial dnaA protein
HCIEOBLE_00789 5.9e-157 xkdB K sequence-specific DNA binding
HCIEOBLE_00791 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HCIEOBLE_00792 2.3e-110 xkdA E IrrE N-terminal-like domain
HCIEOBLE_00793 4.4e-160 ydbD P Catalase
HCIEOBLE_00794 1.3e-110 yjqB S Pfam:DUF867
HCIEOBLE_00795 1.8e-60 yjqA S Bacterial PH domain
HCIEOBLE_00796 5.9e-169 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HCIEOBLE_00797 5.3e-40 S YCII-related domain
HCIEOBLE_00799 3.9e-212 S response regulator aspartate phosphatase
HCIEOBLE_00800 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HCIEOBLE_00801 2.3e-78 yjoA S DinB family
HCIEOBLE_00802 7.4e-130 MA20_18170 S membrane transporter protein
HCIEOBLE_00803 7.3e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HCIEOBLE_00804 1.1e-283 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HCIEOBLE_00805 6.8e-184 exuR K transcriptional
HCIEOBLE_00806 4.1e-226 exuT G Sugar (and other) transporter
HCIEOBLE_00807 6.8e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEOBLE_00808 1.5e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HCIEOBLE_00809 2.1e-188 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HCIEOBLE_00810 9.3e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HCIEOBLE_00811 2.1e-247 yjmB G symporter YjmB
HCIEOBLE_00812 2.2e-276 uxaC 5.3.1.12 G glucuronate isomerase
HCIEOBLE_00813 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
HCIEOBLE_00814 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HCIEOBLE_00815 2.2e-90 yjlB S Cupin domain
HCIEOBLE_00816 3.9e-55 yjlA EG Putative multidrug resistance efflux transporter
HCIEOBLE_00817 2.6e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HCIEOBLE_00818 9.5e-122 ybbM S transport system, permease component
HCIEOBLE_00819 4.9e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HCIEOBLE_00820 1.4e-29
HCIEOBLE_00821 3.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HCIEOBLE_00822 4.4e-222 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HCIEOBLE_00824 2.1e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HCIEOBLE_00825 2e-10 S Domain of unknown function (DUF4352)
HCIEOBLE_00826 5.7e-95 yjgD S Protein of unknown function (DUF1641)
HCIEOBLE_00827 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HCIEOBLE_00828 2e-103 yjgB S Domain of unknown function (DUF4309)
HCIEOBLE_00829 4.9e-34 T PhoQ Sensor
HCIEOBLE_00830 8.9e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
HCIEOBLE_00831 2.3e-20 yjfB S Putative motility protein
HCIEOBLE_00832 5.1e-81 S Protein of unknown function (DUF2690)
HCIEOBLE_00833 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
HCIEOBLE_00835 3.6e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HCIEOBLE_00836 3.5e-52 yjdJ S Domain of unknown function (DUF4306)
HCIEOBLE_00837 9.3e-29 S Domain of unknown function (DUF4177)
HCIEOBLE_00838 2.2e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCIEOBLE_00840 3.4e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HCIEOBLE_00841 3e-45 yjdF S Protein of unknown function (DUF2992)
HCIEOBLE_00842 1.4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
HCIEOBLE_00843 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HCIEOBLE_00844 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HCIEOBLE_00846 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HCIEOBLE_00847 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
HCIEOBLE_00848 5.9e-13
HCIEOBLE_00849 7.2e-80 L Transposase
HCIEOBLE_00852 4.4e-44 yjcN
HCIEOBLE_00853 3e-189 S Putative amidase domain
HCIEOBLE_00857 2.8e-208 yjcL S Protein of unknown function (DUF819)
HCIEOBLE_00858 6.5e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
HCIEOBLE_00859 9.4e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HCIEOBLE_00860 1.5e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HCIEOBLE_00861 2.9e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
HCIEOBLE_00862 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HCIEOBLE_00863 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCIEOBLE_00864 1.7e-38
HCIEOBLE_00865 0.0 yjcD 3.6.4.12 L DNA helicase
HCIEOBLE_00866 2.9e-38 spoVIF S Stage VI sporulation protein F
HCIEOBLE_00869 4.3e-56 yjcA S Protein of unknown function (DUF1360)
HCIEOBLE_00870 2.3e-55 cotV S Spore Coat Protein X and V domain
HCIEOBLE_00871 8.5e-32 cotW
HCIEOBLE_00872 6.4e-77 cotX S Spore Coat Protein X and V domain
HCIEOBLE_00873 3.4e-96 cotY S Spore coat protein Z
HCIEOBLE_00874 5.2e-83 cotZ S Spore coat protein
HCIEOBLE_00875 3.8e-53 yjbX S Spore coat protein
HCIEOBLE_00876 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HCIEOBLE_00877 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCIEOBLE_00878 1.3e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HCIEOBLE_00879 5.8e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HCIEOBLE_00880 1.5e-29 thiS H thiamine diphosphate biosynthetic process
HCIEOBLE_00881 1.7e-215 thiO 1.4.3.19 E Glycine oxidase
HCIEOBLE_00882 1.6e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HCIEOBLE_00883 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HCIEOBLE_00884 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCIEOBLE_00885 2.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HCIEOBLE_00886 2.3e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCIEOBLE_00887 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCIEOBLE_00888 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HCIEOBLE_00889 7.1e-62 yjbL S Belongs to the UPF0738 family
HCIEOBLE_00890 1.2e-100 yjbK S protein conserved in bacteria
HCIEOBLE_00891 2.9e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HCIEOBLE_00892 3.7e-72 yjbI S Bacterial-like globin
HCIEOBLE_00893 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HCIEOBLE_00895 1.8e-20
HCIEOBLE_00896 0.0 pepF E oligoendopeptidase F
HCIEOBLE_00897 1.6e-221 yjbF S Competence protein
HCIEOBLE_00898 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HCIEOBLE_00899 2.3e-111 yjbE P Integral membrane protein TerC family
HCIEOBLE_00900 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCIEOBLE_00901 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCIEOBLE_00902 7e-204 yjbB EGP Major Facilitator Superfamily
HCIEOBLE_00903 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HCIEOBLE_00904 6.8e-198 oppD P Belongs to the ABC transporter superfamily
HCIEOBLE_00905 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEOBLE_00906 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEOBLE_00907 0.0 oppA E ABC transporter substrate-binding protein
HCIEOBLE_00908 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HCIEOBLE_00909 1.9e-146 yjbA S Belongs to the UPF0736 family
HCIEOBLE_00910 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEOBLE_00911 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIEOBLE_00912 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HCIEOBLE_00913 4.2e-186 appF E Belongs to the ABC transporter superfamily
HCIEOBLE_00914 1.8e-184 appD P Belongs to the ABC transporter superfamily
HCIEOBLE_00915 2.8e-148 yjaZ O Zn-dependent protease
HCIEOBLE_00916 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCIEOBLE_00917 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCIEOBLE_00918 5e-21 yjzB
HCIEOBLE_00919 7.3e-26 comZ S ComZ
HCIEOBLE_00920 4.2e-183 med S Transcriptional activator protein med
HCIEOBLE_00921 5.8e-100 yjaV
HCIEOBLE_00922 5.2e-141 yjaU I carboxylic ester hydrolase activity
HCIEOBLE_00923 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HCIEOBLE_00924 9.5e-28 yjzC S YjzC-like protein
HCIEOBLE_00925 2.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCIEOBLE_00926 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HCIEOBLE_00927 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCIEOBLE_00928 2.1e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HCIEOBLE_00929 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HCIEOBLE_00930 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HCIEOBLE_00931 2.8e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HCIEOBLE_00932 1.7e-88 norB G Major Facilitator Superfamily
HCIEOBLE_00933 3.2e-267 yitY C D-arabinono-1,4-lactone oxidase
HCIEOBLE_00934 1.5e-22 pilT S Proteolipid membrane potential modulator
HCIEOBLE_00935 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HCIEOBLE_00936 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HCIEOBLE_00937 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HCIEOBLE_00939 1.2e-17 S Protein of unknown function (DUF3813)
HCIEOBLE_00940 5e-73 ipi S Intracellular proteinase inhibitor
HCIEOBLE_00941 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HCIEOBLE_00942 8.4e-159 yitS S protein conserved in bacteria
HCIEOBLE_00943 3.2e-308 nprB 3.4.24.28 E Peptidase M4
HCIEOBLE_00944 1.4e-44 yitR S Domain of unknown function (DUF3784)
HCIEOBLE_00945 1.3e-94
HCIEOBLE_00946 1.5e-58 K Transcriptional regulator PadR-like family
HCIEOBLE_00947 7.6e-97 S Sporulation delaying protein SdpA
HCIEOBLE_00948 4e-170
HCIEOBLE_00949 8.5e-94
HCIEOBLE_00950 6.9e-161 cvfB S protein conserved in bacteria
HCIEOBLE_00951 1.9e-54 yajQ S Belongs to the UPF0234 family
HCIEOBLE_00952 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HCIEOBLE_00953 4.6e-71 yjcF S Acetyltransferase (GNAT) domain
HCIEOBLE_00954 2.8e-154 yitH K Acetyltransferase (GNAT) domain
HCIEOBLE_00955 3.4e-228 yitG EGP Major facilitator Superfamily
HCIEOBLE_00956 5.6e-219 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HCIEOBLE_00957 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCIEOBLE_00958 1.6e-140 yitD 4.4.1.19 S synthase
HCIEOBLE_00959 3.7e-120 comB 3.1.3.71 H Belongs to the ComB family
HCIEOBLE_00960 3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HCIEOBLE_00961 3.3e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HCIEOBLE_00962 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HCIEOBLE_00963 1.2e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HCIEOBLE_00964 1.2e-35 mcbG S Pentapeptide repeats (9 copies)
HCIEOBLE_00965 3.7e-271 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCIEOBLE_00966 1.2e-106 argO S Lysine exporter protein LysE YggA
HCIEOBLE_00967 1.8e-92 yisT S DinB family
HCIEOBLE_00968 1e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HCIEOBLE_00969 3.8e-182 purR K helix_turn _helix lactose operon repressor
HCIEOBLE_00970 1.2e-160 yisR K Transcriptional regulator
HCIEOBLE_00971 1.5e-242 yisQ V Mate efflux family protein
HCIEOBLE_00972 4.6e-114 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HCIEOBLE_00973 0.0 asnO 6.3.5.4 E Asparagine synthase
HCIEOBLE_00974 5.8e-100 yisN S Protein of unknown function (DUF2777)
HCIEOBLE_00975 0.0 wprA O Belongs to the peptidase S8 family
HCIEOBLE_00976 3.9e-57 yisL S UPF0344 protein
HCIEOBLE_00977 2.1e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HCIEOBLE_00978 1.1e-172 cotH M Spore Coat
HCIEOBLE_00979 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HCIEOBLE_00980 1.9e-33 gerPA S Spore germination protein
HCIEOBLE_00981 4e-34 gerPB S cell differentiation
HCIEOBLE_00982 5.3e-54 gerPC S Spore germination protein
HCIEOBLE_00983 1.1e-23 gerPD S Spore germination protein
HCIEOBLE_00984 7e-63 gerPE S Spore germination protein GerPE
HCIEOBLE_00985 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HCIEOBLE_00986 1.1e-49 yisB V COG1403 Restriction endonuclease
HCIEOBLE_00987 0.0 sbcC L COG0419 ATPase involved in DNA repair
HCIEOBLE_00988 4.5e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HCIEOBLE_00989 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HCIEOBLE_00990 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HCIEOBLE_00991 3.8e-78 yhjR S Rubrerythrin
HCIEOBLE_00992 0.0 S Sugar transport-related sRNA regulator N-term
HCIEOBLE_00993 1.5e-214 EGP Transmembrane secretion effector
HCIEOBLE_00994 9.3e-201 abrB S membrane
HCIEOBLE_00995 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
HCIEOBLE_00996 1.6e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HCIEOBLE_00997 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HCIEOBLE_00998 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HCIEOBLE_00999 4.9e-213 glcP G Major Facilitator Superfamily
HCIEOBLE_01000 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HCIEOBLE_01001 2.2e-279 yhjG CH FAD binding domain
HCIEOBLE_01002 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HCIEOBLE_01003 9.1e-110 yhjE S SNARE associated Golgi protein
HCIEOBLE_01004 2.5e-59 yhjD
HCIEOBLE_01005 4.5e-26 yhjC S Protein of unknown function (DUF3311)
HCIEOBLE_01006 3.4e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCIEOBLE_01007 1.1e-40 yhjA S Excalibur calcium-binding domain
HCIEOBLE_01008 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
HCIEOBLE_01009 4.2e-109 comK K Competence transcription factor
HCIEOBLE_01010 1.3e-32 yhzC S IDEAL
HCIEOBLE_01011 8e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEOBLE_01012 2.6e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HCIEOBLE_01013 2.7e-180 hemAT NT chemotaxis protein
HCIEOBLE_01014 7.2e-90 bioY S BioY family
HCIEOBLE_01015 4.7e-271 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HCIEOBLE_01016 1.9e-195 vraB 2.3.1.9 I Belongs to the thiolase family
HCIEOBLE_01017 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HCIEOBLE_01018 4.3e-159 yfmC M Periplasmic binding protein
HCIEOBLE_01019 1.2e-180 yhfP 1.1.1.1 C Quinone oxidoreductase
HCIEOBLE_01020 4e-75 VY92_01935 K acetyltransferase
HCIEOBLE_01021 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HCIEOBLE_01022 1.2e-241 yhfN 3.4.24.84 O Peptidase M48
HCIEOBLE_01023 1.9e-65 yhfM
HCIEOBLE_01024 1.6e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HCIEOBLE_01025 2.2e-111 yhfK GM NmrA-like family
HCIEOBLE_01026 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HCIEOBLE_01027 3.1e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HCIEOBLE_01028 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCIEOBLE_01029 1.1e-71 3.4.13.21 S ASCH
HCIEOBLE_01030 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HCIEOBLE_01031 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
HCIEOBLE_01032 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCIEOBLE_01033 4.1e-224 yhgE S YhgE Pip N-terminal domain protein
HCIEOBLE_01034 5.4e-101 yhgD K Transcriptional regulator
HCIEOBLE_01035 1.5e-264 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HCIEOBLE_01036 3.1e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HCIEOBLE_01037 5.9e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HCIEOBLE_01038 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCIEOBLE_01039 1.1e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HCIEOBLE_01040 1.7e-32 1.15.1.2 C Rubrerythrin
HCIEOBLE_01041 2.3e-230 yhfA C membrane
HCIEOBLE_01042 2.8e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HCIEOBLE_01043 6.9e-114 ecsC S EcsC protein family
HCIEOBLE_01044 7.8e-214 ecsB U ABC transporter
HCIEOBLE_01045 1e-136 ecsA V transporter (ATP-binding protein)
HCIEOBLE_01046 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HCIEOBLE_01047 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HCIEOBLE_01048 3.6e-80 trpP S Tryptophan transporter TrpP
HCIEOBLE_01049 5.4e-39 yhaH S YtxH-like protein
HCIEOBLE_01050 1e-113 hpr K Negative regulator of protease production and sporulation
HCIEOBLE_01051 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HCIEOBLE_01052 1.1e-89 yhaK S Putative zincin peptidase
HCIEOBLE_01053 8.8e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCIEOBLE_01054 1.6e-21 yhaL S Sporulation protein YhaL
HCIEOBLE_01055 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HCIEOBLE_01056 0.0 yhaN L AAA domain
HCIEOBLE_01057 7e-223 yhaO L DNA repair exonuclease
HCIEOBLE_01058 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HCIEOBLE_01059 5.2e-167 yhaQ S ABC transporter, ATP-binding protein
HCIEOBLE_01060 2.4e-26 S YhzD-like protein
HCIEOBLE_01061 5.5e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
HCIEOBLE_01063 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HCIEOBLE_01064 6.3e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HCIEOBLE_01065 5.6e-291 hemZ H coproporphyrinogen III oxidase
HCIEOBLE_01066 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HCIEOBLE_01067 4.9e-204 yhaZ L DNA alkylation repair enzyme
HCIEOBLE_01068 9.5e-48 yheA S Belongs to the UPF0342 family
HCIEOBLE_01069 6.3e-202 yheB S Belongs to the UPF0754 family
HCIEOBLE_01070 4.3e-216 yheC HJ YheC/D like ATP-grasp
HCIEOBLE_01071 4.8e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HCIEOBLE_01072 1.3e-36 yheE S Family of unknown function (DUF5342)
HCIEOBLE_01073 6.3e-28 sspB S spore protein
HCIEOBLE_01074 1.7e-108 yheG GM NAD(P)H-binding
HCIEOBLE_01075 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCIEOBLE_01076 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCIEOBLE_01077 1.7e-83 nhaX T Belongs to the universal stress protein A family
HCIEOBLE_01078 1.5e-229 nhaC C Na H antiporter
HCIEOBLE_01079 4e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HCIEOBLE_01080 2.1e-146 yheN G deacetylase
HCIEOBLE_01081 5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HCIEOBLE_01082 8.1e-202 yhdY M Mechanosensitive ion channel
HCIEOBLE_01084 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCIEOBLE_01085 2.8e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCIEOBLE_01086 8.4e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCIEOBLE_01087 6e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HCIEOBLE_01088 1.3e-221 yhdR 2.6.1.1 E Aminotransferase
HCIEOBLE_01089 4.1e-74 cueR K transcriptional
HCIEOBLE_01090 6.9e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HCIEOBLE_01091 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HCIEOBLE_01092 2e-191 yhdN C Aldo keto reductase
HCIEOBLE_01093 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HCIEOBLE_01094 2.5e-200 yhdL S Sigma factor regulator N-terminal
HCIEOBLE_01095 8.1e-45 yhdK S Sigma-M inhibitor protein
HCIEOBLE_01096 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCIEOBLE_01097 1.2e-80 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCIEOBLE_01098 2.5e-158 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCIEOBLE_01099 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HCIEOBLE_01100 3.4e-250 yhdG E amino acid
HCIEOBLE_01101 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEOBLE_01102 5.9e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
HCIEOBLE_01103 3.8e-162 citR K Transcriptional regulator
HCIEOBLE_01104 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HCIEOBLE_01105 2.5e-253 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HCIEOBLE_01106 2.1e-276 ycgB S Stage V sporulation protein R
HCIEOBLE_01107 7.6e-235 ygxB M Conserved TM helix
HCIEOBLE_01108 3.9e-75 nsrR K Transcriptional regulator
HCIEOBLE_01109 2.3e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HCIEOBLE_01110 2e-52 yhdC S Protein of unknown function (DUF3889)
HCIEOBLE_01111 1.2e-38 yhdB S YhdB-like protein
HCIEOBLE_01112 2.7e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
HCIEOBLE_01113 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCIEOBLE_01114 8.8e-212 yhcY 2.7.13.3 T Histidine kinase
HCIEOBLE_01115 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HCIEOBLE_01116 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HCIEOBLE_01117 1e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCIEOBLE_01118 4.3e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HCIEOBLE_01119 1.2e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HCIEOBLE_01120 6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCIEOBLE_01121 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HCIEOBLE_01122 5.1e-119 yhcW 5.4.2.6 S hydrolase
HCIEOBLE_01123 9.9e-68 yhcV S COG0517 FOG CBS domain
HCIEOBLE_01124 2.1e-67 yhcU S Family of unknown function (DUF5365)
HCIEOBLE_01125 8.1e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCIEOBLE_01126 1.7e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HCIEOBLE_01127 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HCIEOBLE_01128 5.8e-99 yhcQ M Spore coat protein
HCIEOBLE_01129 7.6e-164 yhcP
HCIEOBLE_01130 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCIEOBLE_01131 3.2e-40 yhcM
HCIEOBLE_01132 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCIEOBLE_01133 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HCIEOBLE_01134 8.3e-151 metQ M Belongs to the nlpA lipoprotein family
HCIEOBLE_01135 1e-30 cspB K Cold-shock protein
HCIEOBLE_01136 1.9e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HCIEOBLE_01137 7.7e-166 yhcH V ABC transporter, ATP-binding protein
HCIEOBLE_01138 4e-122 yhcG V ABC transporter, ATP-binding protein
HCIEOBLE_01139 1.9e-59 yhcF K Transcriptional regulator
HCIEOBLE_01140 3e-54
HCIEOBLE_01141 2.8e-37 yhcC
HCIEOBLE_01142 1.4e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HCIEOBLE_01143 3.1e-271 yhcA EGP Major facilitator Superfamily
HCIEOBLE_01144 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HCIEOBLE_01145 3.7e-76 yhbI K DNA-binding transcription factor activity
HCIEOBLE_01146 2.5e-225 yhbH S Belongs to the UPF0229 family
HCIEOBLE_01147 0.0 prkA T Ser protein kinase
HCIEOBLE_01148 9.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HCIEOBLE_01149 2.7e-57 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HCIEOBLE_01150 7.9e-109 yhbD K Protein of unknown function (DUF4004)
HCIEOBLE_01151 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCIEOBLE_01152 4.8e-176 yhbB S Putative amidase domain
HCIEOBLE_01153 1.7e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HCIEOBLE_01154 1.9e-112 yhzB S B3/4 domain
HCIEOBLE_01156 4.4e-29 K Transcriptional regulator
HCIEOBLE_01157 2.6e-77 ygaO
HCIEOBLE_01158 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCIEOBLE_01160 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HCIEOBLE_01161 1.9e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCIEOBLE_01162 4.3e-170 ssuA M Sulfonate ABC transporter
HCIEOBLE_01163 9.7e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HCIEOBLE_01164 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HCIEOBLE_01166 1e-262 ygaK C Berberine and berberine like
HCIEOBLE_01167 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HCIEOBLE_01168 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HCIEOBLE_01169 1.2e-26
HCIEOBLE_01170 7.2e-141 spo0M S COG4326 Sporulation control protein
HCIEOBLE_01174 2e-08
HCIEOBLE_01178 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCIEOBLE_01179 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCIEOBLE_01180 1.8e-37 yaaB S Domain of unknown function (DUF370)
HCIEOBLE_01181 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCIEOBLE_01182 2.4e-33 yaaA S S4 domain
HCIEOBLE_01183 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCIEOBLE_01184 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCIEOBLE_01185 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCIEOBLE_01186 2.5e-117 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCIEOBLE_01187 1.5e-107 jag S single-stranded nucleic acid binding R3H
HCIEOBLE_01188 2.2e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCIEOBLE_01189 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCIEOBLE_01190 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HCIEOBLE_01191 2.7e-149 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HCIEOBLE_01192 9.6e-74 S Bacterial PH domain
HCIEOBLE_01193 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HCIEOBLE_01194 2.1e-149 spo0J K Belongs to the ParB family
HCIEOBLE_01195 1.6e-111 yyaC S Sporulation protein YyaC
HCIEOBLE_01196 1.8e-176 yyaD S Membrane
HCIEOBLE_01197 2.3e-33 yyzM S protein conserved in bacteria
HCIEOBLE_01198 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCIEOBLE_01199 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCIEOBLE_01200 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HCIEOBLE_01201 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCIEOBLE_01202 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCIEOBLE_01203 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
HCIEOBLE_01204 8.3e-176 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HCIEOBLE_01205 8.4e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCIEOBLE_01206 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HCIEOBLE_01207 8.8e-243 EGP Major facilitator superfamily
HCIEOBLE_01208 1.1e-167 yyaK S CAAX protease self-immunity
HCIEOBLE_01209 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HCIEOBLE_01211 7.8e-61
HCIEOBLE_01212 1.1e-53 L Recombinase
HCIEOBLE_01214 1.3e-60 S Protein of unknown function DUF86
HCIEOBLE_01215 3.6e-30 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HCIEOBLE_01216 1.7e-151 eaeH M Domain of Unknown Function (DUF1259)
HCIEOBLE_01218 1.6e-92 yyaS S Membrane
HCIEOBLE_01219 4.2e-69 yjcF S Acetyltransferase (GNAT) domain
HCIEOBLE_01220 1.6e-76 yybA 2.3.1.57 K transcriptional
HCIEOBLE_01221 2.8e-125 S Metallo-beta-lactamase superfamily
HCIEOBLE_01222 6.6e-76 yybC
HCIEOBLE_01223 6.5e-78 yjcF S Acetyltransferase (GNAT) domain
HCIEOBLE_01224 5.8e-163 yybE K Transcriptional regulator
HCIEOBLE_01225 6.7e-218 ynfM EGP Major facilitator Superfamily
HCIEOBLE_01226 1.7e-119 yybG S Pentapeptide repeat-containing protein
HCIEOBLE_01227 1.7e-66 yybH S SnoaL-like domain
HCIEOBLE_01228 8.2e-124
HCIEOBLE_01229 3.3e-111 K TipAS antibiotic-recognition domain
HCIEOBLE_01230 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HCIEOBLE_01232 1.2e-58
HCIEOBLE_01233 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HCIEOBLE_01234 1.7e-66 ydeP3 K Transcriptional regulator
HCIEOBLE_01235 3.9e-84 cotF M Spore coat protein
HCIEOBLE_01237 1.4e-159 yybS S membrane
HCIEOBLE_01238 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HCIEOBLE_01239 2.2e-73 rplI J binds to the 23S rRNA
HCIEOBLE_01240 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCIEOBLE_01241 2.5e-220 yeaN P COG2807 Cyanate permease
HCIEOBLE_01242 1.9e-15 yycC K YycC-like protein
HCIEOBLE_01244 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HCIEOBLE_01245 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HCIEOBLE_01246 8.9e-77 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCIEOBLE_01247 1.5e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCIEOBLE_01252 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_01253 0.0 vicK 2.7.13.3 T Histidine kinase
HCIEOBLE_01254 1.9e-256 yycH S protein conserved in bacteria
HCIEOBLE_01255 7.3e-155 yycI S protein conserved in bacteria
HCIEOBLE_01256 3.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HCIEOBLE_01257 7.1e-220 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCIEOBLE_01258 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HCIEOBLE_01259 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HCIEOBLE_01260 1.3e-260 rocE E amino acid
HCIEOBLE_01261 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HCIEOBLE_01263 8.5e-188 S aspartate phosphatase
HCIEOBLE_01264 1.1e-83 yycN 2.3.1.128 K Acetyltransferase
HCIEOBLE_01265 2.1e-129 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HCIEOBLE_01266 2.7e-208 yycP
HCIEOBLE_01267 1.7e-30 yycQ S Protein of unknown function (DUF2651)
HCIEOBLE_01269 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HCIEOBLE_01270 4.4e-68
HCIEOBLE_01271 1.1e-09 S YyzF-like protein
HCIEOBLE_01272 1.5e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCIEOBLE_01273 6e-99
HCIEOBLE_01274 3.6e-11
HCIEOBLE_01275 5.1e-293 D Protein of unknown function (DUF3732)
HCIEOBLE_01276 2.7e-118 mobC K Transcriptional regulator
HCIEOBLE_01278 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HCIEOBLE_01279 1.1e-08
HCIEOBLE_01280 2.7e-126 yydK K Transcriptional regulator
HCIEOBLE_01281 3.9e-17 bglF G phosphotransferase system
HCIEOBLE_01282 2.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIEOBLE_01283 1.2e-188 wgaE S Polysaccharide pyruvyl transferase
HCIEOBLE_01284 1.2e-285 ahpF O Alkyl hydroperoxide reductase
HCIEOBLE_01285 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HCIEOBLE_01286 2.1e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCIEOBLE_01287 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HCIEOBLE_01288 1.9e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HCIEOBLE_01289 7.3e-127 gntR K transcriptional
HCIEOBLE_01290 8e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HCIEOBLE_01291 5.9e-191 yxaB GM Polysaccharide pyruvyl transferase
HCIEOBLE_01292 2.6e-118 yxaC M effector of murein hydrolase
HCIEOBLE_01293 5.2e-50 S LrgA family
HCIEOBLE_01294 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HCIEOBLE_01295 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEOBLE_01296 2.7e-100 yxaF K Transcriptional regulator
HCIEOBLE_01297 2.1e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
HCIEOBLE_01298 2.7e-227 P Protein of unknown function (DUF418)
HCIEOBLE_01299 1.4e-75 yxaI S membrane protein domain
HCIEOBLE_01300 1.5e-63 S Family of unknown function (DUF5391)
HCIEOBLE_01301 2.2e-91 S PQQ-like domain
HCIEOBLE_01302 1.4e-20 yxaI S membrane protein domain
HCIEOBLE_01303 9.9e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HCIEOBLE_01304 6.2e-197 yxbF K Bacterial regulatory proteins, tetR family
HCIEOBLE_01305 1.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
HCIEOBLE_01307 0.0 htpG O Molecular chaperone. Has ATPase activity
HCIEOBLE_01308 1.5e-245 csbC EGP Major facilitator Superfamily
HCIEOBLE_01309 3e-79 T HPP family
HCIEOBLE_01310 1.9e-90 S CGNR zinc finger
HCIEOBLE_01311 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HCIEOBLE_01313 8.3e-176 iolS C Aldo keto reductase
HCIEOBLE_01314 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HCIEOBLE_01315 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCIEOBLE_01316 1e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HCIEOBLE_01317 1.2e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HCIEOBLE_01318 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HCIEOBLE_01319 4e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HCIEOBLE_01320 9.6e-234 iolF EGP Major facilitator Superfamily
HCIEOBLE_01321 3.1e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HCIEOBLE_01322 1.9e-166 iolH G Xylose isomerase-like TIM barrel
HCIEOBLE_01323 4.7e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HCIEOBLE_01324 2.5e-158 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HCIEOBLE_01325 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_01326 2e-180 T PhoQ Sensor
HCIEOBLE_01327 2.6e-138 yxdL V ABC transporter, ATP-binding protein
HCIEOBLE_01328 0.0 yxdM V ABC transporter (permease)
HCIEOBLE_01329 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HCIEOBLE_01330 9.5e-175 fhuD P ABC transporter
HCIEOBLE_01331 8.5e-69
HCIEOBLE_01332 5.6e-16 yxeD
HCIEOBLE_01333 1.3e-20 yxeE
HCIEOBLE_01336 2.6e-149 yidA S hydrolases of the HAD superfamily
HCIEOBLE_01337 1.4e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HCIEOBLE_01338 1.2e-252 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCIEOBLE_01339 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCIEOBLE_01340 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HCIEOBLE_01341 1.6e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
HCIEOBLE_01342 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HCIEOBLE_01343 7.2e-214 yxeP 3.5.1.47 E hydrolase activity
HCIEOBLE_01344 1.5e-250 yxeQ S MmgE/PrpD family
HCIEOBLE_01345 3.6e-194 eutH E Ethanolamine utilisation protein, EutH
HCIEOBLE_01346 2.2e-151 yxxB S Domain of Unknown Function (DUF1206)
HCIEOBLE_01349 1.2e-72 V ATPases associated with a variety of cellular activities
HCIEOBLE_01351 9.7e-72
HCIEOBLE_01352 1.6e-28
HCIEOBLE_01353 2.4e-27 KT COG4219 Antirepressor regulating drug resistance
HCIEOBLE_01354 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HCIEOBLE_01355 2.2e-114 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HCIEOBLE_01356 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HCIEOBLE_01357 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HCIEOBLE_01358 9.8e-250 lysP E amino acid
HCIEOBLE_01359 2.8e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HCIEOBLE_01360 3.1e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HCIEOBLE_01361 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HCIEOBLE_01362 1.7e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
HCIEOBLE_01363 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HCIEOBLE_01364 7.4e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HCIEOBLE_01365 2.3e-20 S Domain of unknown function (DUF5082)
HCIEOBLE_01366 1.4e-38 yxiC S Family of unknown function (DUF5344)
HCIEOBLE_01367 4e-199 S nuclease activity
HCIEOBLE_01368 1.6e-50
HCIEOBLE_01369 3.8e-21 S Uncharacterized protein conserved in bacteria (DUF2247)
HCIEOBLE_01370 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCIEOBLE_01371 7.6e-277 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIEOBLE_01372 5.4e-72 yxiE T Belongs to the universal stress protein A family
HCIEOBLE_01373 1.3e-165 yxxF EG EamA-like transporter family
HCIEOBLE_01374 0.0 wapA M COG3209 Rhs family protein
HCIEOBLE_01375 9.6e-14
HCIEOBLE_01376 2.4e-137
HCIEOBLE_01377 5.8e-88 yxiI S Protein of unknown function (DUF2716)
HCIEOBLE_01378 7.7e-43 yxiJ S YxiJ-like protein
HCIEOBLE_01381 2.8e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HCIEOBLE_01382 6.2e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HCIEOBLE_01383 4.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
HCIEOBLE_01384 3.1e-111
HCIEOBLE_01385 3.1e-150 licT K transcriptional antiterminator
HCIEOBLE_01386 1.1e-143 exoK GH16 M licheninase activity
HCIEOBLE_01387 4.3e-223 citH C Citrate transporter
HCIEOBLE_01388 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HCIEOBLE_01389 5.6e-46 yxiS
HCIEOBLE_01390 1.2e-104 T Domain of unknown function (DUF4163)
HCIEOBLE_01391 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HCIEOBLE_01392 2.4e-158 rlmA 2.1.1.187 Q Methyltransferase domain
HCIEOBLE_01393 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HCIEOBLE_01394 6.9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HCIEOBLE_01395 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HCIEOBLE_01396 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HCIEOBLE_01397 1.1e-217 yxjG 2.1.1.14 E Methionine synthase
HCIEOBLE_01398 2.8e-218 yxjG 2.1.1.14 E Methionine synthase
HCIEOBLE_01399 6e-85 yxjI S LURP-one-related
HCIEOBLE_01402 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HCIEOBLE_01403 3.7e-114 K helix_turn_helix, Lux Regulon
HCIEOBLE_01404 1.2e-190 yxjM T Signal transduction histidine kinase
HCIEOBLE_01405 6.9e-78 S Protein of unknown function (DUF1453)
HCIEOBLE_01406 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HCIEOBLE_01407 2.8e-74 yxkC S Domain of unknown function (DUF4352)
HCIEOBLE_01408 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCIEOBLE_01409 2.7e-274 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCIEOBLE_01410 3.5e-163 lrp QT PucR C-terminal helix-turn-helix domain
HCIEOBLE_01411 2.9e-204 msmK P Belongs to the ABC transporter superfamily
HCIEOBLE_01412 6.2e-154 yxkH G Polysaccharide deacetylase
HCIEOBLE_01414 6.7e-309 3.4.24.84 O Peptidase family M48
HCIEOBLE_01415 2.5e-229 cimH C COG3493 Na citrate symporter
HCIEOBLE_01416 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
HCIEOBLE_01417 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HCIEOBLE_01418 1.4e-309 cydD V ATP-binding
HCIEOBLE_01419 0.0 cydD V ATP-binding protein
HCIEOBLE_01420 7.7e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCIEOBLE_01421 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HCIEOBLE_01422 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HCIEOBLE_01423 3.9e-48 yxlC S Family of unknown function (DUF5345)
HCIEOBLE_01424 1.4e-30
HCIEOBLE_01425 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HCIEOBLE_01426 4.8e-165 yxlF V ABC transporter, ATP-binding protein
HCIEOBLE_01427 3.4e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HCIEOBLE_01428 1.9e-212 yxlH EGP Major facilitator Superfamily
HCIEOBLE_01429 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HCIEOBLE_01430 1.5e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HCIEOBLE_01431 1.1e-19 yxzF
HCIEOBLE_01432 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HCIEOBLE_01433 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HCIEOBLE_01434 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIEOBLE_01435 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HCIEOBLE_01436 3.2e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HCIEOBLE_01437 5.3e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HCIEOBLE_01438 4.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEOBLE_01439 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCIEOBLE_01440 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIEOBLE_01441 1.2e-232 dltB M membrane protein involved in D-alanine export
HCIEOBLE_01442 9.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIEOBLE_01443 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
HCIEOBLE_01444 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HCIEOBLE_01445 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HCIEOBLE_01446 7.5e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HCIEOBLE_01447 3e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCIEOBLE_01448 4e-87 ywaE K Transcriptional regulator
HCIEOBLE_01449 7.4e-124 ywaF S Integral membrane protein
HCIEOBLE_01450 5e-167 gspA M General stress
HCIEOBLE_01451 1.2e-152 sacY K transcriptional antiterminator
HCIEOBLE_01452 9.9e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCIEOBLE_01453 6.8e-273 epr 3.4.21.62 O Belongs to the peptidase S8 family
HCIEOBLE_01454 1.7e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIEOBLE_01455 2.7e-123 ywbB S Protein of unknown function (DUF2711)
HCIEOBLE_01456 9.9e-67 ywbC 4.4.1.5 E glyoxalase
HCIEOBLE_01457 5.4e-220 ywbD 2.1.1.191 J Methyltransferase
HCIEOBLE_01458 2.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HCIEOBLE_01459 2.8e-208 ywbF EGP Major facilitator Superfamily
HCIEOBLE_01460 2.3e-111 ywbG M effector of murein hydrolase
HCIEOBLE_01461 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HCIEOBLE_01462 1.6e-152 ywbI K Transcriptional regulator
HCIEOBLE_01463 1.1e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCIEOBLE_01464 1.3e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCIEOBLE_01465 7.4e-248 P COG0672 High-affinity Fe2 Pb2 permease
HCIEOBLE_01466 5.5e-185 ycdO P periplasmic lipoprotein involved in iron transport
HCIEOBLE_01467 1.9e-209 ywbN P Dyp-type peroxidase family protein
HCIEOBLE_01468 4.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HCIEOBLE_01469 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCIEOBLE_01470 2.2e-48 ywcB S Protein of unknown function, DUF485
HCIEOBLE_01472 1.1e-121 ywcC K transcriptional regulator
HCIEOBLE_01473 8.1e-59 gtcA S GtrA-like protein
HCIEOBLE_01474 4.9e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCIEOBLE_01475 9.8e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HCIEOBLE_01476 1e-35 ywzA S membrane
HCIEOBLE_01477 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HCIEOBLE_01478 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HCIEOBLE_01479 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HCIEOBLE_01480 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HCIEOBLE_01481 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HCIEOBLE_01482 8.6e-202 rodA D Belongs to the SEDS family
HCIEOBLE_01483 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HCIEOBLE_01484 8.1e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCIEOBLE_01485 0.0 vpr O Belongs to the peptidase S8 family
HCIEOBLE_01487 1.2e-149 sacT K transcriptional antiterminator
HCIEOBLE_01488 4.2e-17 focA P Formate/nitrite transporter
HCIEOBLE_01489 1.6e-106 focA P Formate/nitrite transporter
HCIEOBLE_01490 1.9e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCIEOBLE_01491 7e-291 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HCIEOBLE_01492 2e-28 ywdA
HCIEOBLE_01493 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCIEOBLE_01494 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HCIEOBLE_01495 3.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCIEOBLE_01496 1.1e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HCIEOBLE_01497 7.7e-49 ywdI S Family of unknown function (DUF5327)
HCIEOBLE_01498 3.7e-238 ywdJ F Xanthine uracil
HCIEOBLE_01499 4.3e-59 ywdK S small membrane protein
HCIEOBLE_01500 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HCIEOBLE_01501 2.4e-144 spsA M Spore Coat
HCIEOBLE_01502 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
HCIEOBLE_01503 2.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
HCIEOBLE_01504 8.3e-162 spsD 2.3.1.210 K Spore Coat
HCIEOBLE_01505 3.2e-214 spsE 2.5.1.56 M acid synthase
HCIEOBLE_01506 7e-130 spsF M Spore Coat
HCIEOBLE_01507 2.1e-188 spsG M Spore Coat
HCIEOBLE_01508 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HCIEOBLE_01509 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HCIEOBLE_01510 2e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HCIEOBLE_01511 1.3e-86 spsL 5.1.3.13 M Spore Coat
HCIEOBLE_01512 1.2e-77
HCIEOBLE_01513 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCIEOBLE_01514 6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HCIEOBLE_01515 0.0 rocB E arginine degradation protein
HCIEOBLE_01516 7.4e-250 lysP E amino acid
HCIEOBLE_01517 8.7e-205 ywfA EGP Major facilitator Superfamily
HCIEOBLE_01518 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HCIEOBLE_01519 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HCIEOBLE_01520 1.1e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEOBLE_01521 8e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HCIEOBLE_01522 5.6e-209 bacE EGP Major facilitator Superfamily
HCIEOBLE_01523 1.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
HCIEOBLE_01524 1.7e-137 IQ Enoyl-(Acyl carrier protein) reductase
HCIEOBLE_01525 3.3e-146 ywfI C May function as heme-dependent peroxidase
HCIEOBLE_01526 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HCIEOBLE_01527 1.1e-156 cysL K Transcriptional regulator
HCIEOBLE_01528 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HCIEOBLE_01529 2.8e-157 ywfM EG EamA-like transporter family
HCIEOBLE_01530 1e-110 rsfA_1
HCIEOBLE_01531 3.1e-36 ywzC S Belongs to the UPF0741 family
HCIEOBLE_01532 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
HCIEOBLE_01533 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HCIEOBLE_01534 2e-77 yffB K Transcriptional regulator
HCIEOBLE_01535 1.5e-237 mmr U Major Facilitator Superfamily
HCIEOBLE_01537 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCIEOBLE_01538 3.3e-71 ywhA K Transcriptional regulator
HCIEOBLE_01539 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HCIEOBLE_01540 5.1e-119 ywhC S Peptidase family M50
HCIEOBLE_01541 2e-94 ywhD S YwhD family
HCIEOBLE_01542 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCIEOBLE_01543 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HCIEOBLE_01544 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HCIEOBLE_01545 1.4e-27 ywhH S Aminoacyl-tRNA editing domain
HCIEOBLE_01547 3.1e-79 S aspartate phosphatase
HCIEOBLE_01548 2e-194 ywhK CO amine dehydrogenase activity
HCIEOBLE_01549 1.3e-230 ywhL CO amine dehydrogenase activity
HCIEOBLE_01551 1e-245 L Peptidase, M16
HCIEOBLE_01552 5.5e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
HCIEOBLE_01553 1.9e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HCIEOBLE_01554 1.3e-131 cbiO V ABC transporter
HCIEOBLE_01556 4.9e-270 C Fe-S oxidoreductases
HCIEOBLE_01557 1e-07 S Bacteriocin subtilosin A
HCIEOBLE_01558 4.7e-73 ywiB S protein conserved in bacteria
HCIEOBLE_01559 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HCIEOBLE_01560 5e-213 narK P COG2223 Nitrate nitrite transporter
HCIEOBLE_01561 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HCIEOBLE_01562 8.2e-139 ywiC S YwiC-like protein
HCIEOBLE_01563 7e-86 arfM T cyclic nucleotide binding
HCIEOBLE_01564 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCIEOBLE_01565 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
HCIEOBLE_01566 1.1e-93 narJ 1.7.5.1 C nitrate reductase
HCIEOBLE_01567 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
HCIEOBLE_01568 1.9e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCIEOBLE_01569 0.0 ywjA V ABC transporter
HCIEOBLE_01570 2.6e-94 ywjB H RibD C-terminal domain
HCIEOBLE_01571 2.7e-42 ywjC
HCIEOBLE_01572 3.6e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HCIEOBLE_01573 1.4e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HCIEOBLE_01574 0.0 fadF C COG0247 Fe-S oxidoreductase
HCIEOBLE_01575 6.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HCIEOBLE_01576 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCIEOBLE_01577 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCIEOBLE_01578 6e-91 ywjG S Domain of unknown function (DUF2529)
HCIEOBLE_01579 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HCIEOBLE_01580 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HCIEOBLE_01581 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCIEOBLE_01582 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCIEOBLE_01583 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HCIEOBLE_01584 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCIEOBLE_01585 1.1e-32 rpmE J Binds the 23S rRNA
HCIEOBLE_01586 7e-104 tdk 2.7.1.21 F thymidine kinase
HCIEOBLE_01587 0.0 sfcA 1.1.1.38 C malic enzyme
HCIEOBLE_01588 8.6e-160 ywkB S Membrane transport protein
HCIEOBLE_01589 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HCIEOBLE_01590 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCIEOBLE_01591 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCIEOBLE_01592 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCIEOBLE_01594 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
HCIEOBLE_01595 6.1e-112 spoIIR S stage II sporulation protein R
HCIEOBLE_01596 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HCIEOBLE_01597 2.6e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCIEOBLE_01598 1.7e-91 mntP P Probably functions as a manganese efflux pump
HCIEOBLE_01599 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCIEOBLE_01600 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HCIEOBLE_01601 7.2e-95 ywlG S Belongs to the UPF0340 family
HCIEOBLE_01602 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCIEOBLE_01603 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCIEOBLE_01604 2.5e-62 atpI S ATP synthase
HCIEOBLE_01605 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HCIEOBLE_01606 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCIEOBLE_01607 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCIEOBLE_01608 1.7e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCIEOBLE_01609 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCIEOBLE_01610 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCIEOBLE_01611 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCIEOBLE_01612 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HCIEOBLE_01613 1.1e-86 ywmA
HCIEOBLE_01614 1.3e-32 ywzB S membrane
HCIEOBLE_01615 8.2e-134 ywmB S TATA-box binding
HCIEOBLE_01616 2.3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCIEOBLE_01617 2.7e-175 spoIID D Stage II sporulation protein D
HCIEOBLE_01618 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HCIEOBLE_01619 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HCIEOBLE_01621 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HCIEOBLE_01622 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HCIEOBLE_01623 1.3e-103 S response regulator aspartate phosphatase
HCIEOBLE_01624 3e-84 ywmF S Peptidase M50
HCIEOBLE_01625 3.8e-11 csbD K CsbD-like
HCIEOBLE_01626 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HCIEOBLE_01627 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HCIEOBLE_01628 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HCIEOBLE_01629 1.7e-64 ywnA K Transcriptional regulator
HCIEOBLE_01630 1.1e-113 ywnB S NAD(P)H-binding
HCIEOBLE_01631 1.7e-58 ywnC S Family of unknown function (DUF5362)
HCIEOBLE_01632 5.3e-144 mta K transcriptional
HCIEOBLE_01633 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCIEOBLE_01634 2.9e-70 ywnF S Family of unknown function (DUF5392)
HCIEOBLE_01635 8.6e-13 ywnC S Family of unknown function (DUF5362)
HCIEOBLE_01636 2.7e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HCIEOBLE_01637 2.6e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HCIEOBLE_01638 7.8e-73 ywnJ S VanZ like family
HCIEOBLE_01639 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HCIEOBLE_01640 1.6e-58 nrgB K Belongs to the P(II) protein family
HCIEOBLE_01641 2.5e-225 amt P Ammonium transporter
HCIEOBLE_01642 1.2e-77
HCIEOBLE_01643 6.8e-104 phzA Q Isochorismatase family
HCIEOBLE_01644 2.4e-240 ywoD EGP Major facilitator superfamily
HCIEOBLE_01645 1.7e-279 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HCIEOBLE_01646 4.9e-228 ywoF P Right handed beta helix region
HCIEOBLE_01648 2.7e-211 ywoG EGP Major facilitator Superfamily
HCIEOBLE_01649 2.1e-70 ywoH K COG1846 Transcriptional regulators
HCIEOBLE_01650 3e-44 spoIIID K Stage III sporulation protein D
HCIEOBLE_01651 3.5e-180 mbl D Rod shape-determining protein
HCIEOBLE_01652 1.7e-124 flhO N flagellar basal body
HCIEOBLE_01653 1.1e-139 flhP N flagellar basal body
HCIEOBLE_01654 7.5e-197 S aspartate phosphatase
HCIEOBLE_01655 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCIEOBLE_01656 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCIEOBLE_01657 0.0 ywpD T PhoQ Sensor
HCIEOBLE_01658 3.4e-173 M1-574 T Transcriptional regulatory protein, C terminal
HCIEOBLE_01659 0.0 M1-568 M cell wall anchor domain
HCIEOBLE_01660 3e-84 srtA 3.4.22.70 M Sortase family
HCIEOBLE_01661 1.1e-66 ywpF S YwpF-like protein
HCIEOBLE_01662 3.8e-66 ywpG
HCIEOBLE_01663 3.7e-57 ssbB L Single-stranded DNA-binding protein
HCIEOBLE_01664 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HCIEOBLE_01665 1.8e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HCIEOBLE_01666 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HCIEOBLE_01667 4.6e-307 ywqB S SWIM zinc finger
HCIEOBLE_01668 1.2e-17
HCIEOBLE_01669 2e-116 ywqC M biosynthesis protein
HCIEOBLE_01670 1.3e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HCIEOBLE_01671 2.1e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HCIEOBLE_01672 2.8e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCIEOBLE_01673 4.9e-153 ywqG S Domain of unknown function (DUF1963)
HCIEOBLE_01674 1.3e-19 S Domain of unknown function (DUF5082)
HCIEOBLE_01675 2e-37 ywqI S Family of unknown function (DUF5344)
HCIEOBLE_01676 5.4e-243 ywqJ S Pre-toxin TG
HCIEOBLE_01677 3.9e-25
HCIEOBLE_01678 1.9e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HCIEOBLE_01679 1.4e-161 K Transcriptional regulator
HCIEOBLE_01680 3.5e-97 ywqN S NAD(P)H-dependent
HCIEOBLE_01682 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
HCIEOBLE_01683 7.1e-104 ywrB P Chromate transporter
HCIEOBLE_01684 5.2e-81 ywrC K Transcriptional regulator
HCIEOBLE_01685 5.5e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HCIEOBLE_01686 2.4e-33 S Domain of unknown function (DUF4181)
HCIEOBLE_01687 3.2e-101 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HCIEOBLE_01688 1.3e-12
HCIEOBLE_01689 1.8e-206 cotH M Spore Coat
HCIEOBLE_01690 7.6e-129 cotB
HCIEOBLE_01691 2e-123 ywrJ
HCIEOBLE_01692 2.7e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HCIEOBLE_01693 1.1e-169 alsR K LysR substrate binding domain
HCIEOBLE_01694 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HCIEOBLE_01695 1.8e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HCIEOBLE_01696 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HCIEOBLE_01697 8e-48 ywsA S Protein of unknown function (DUF3892)
HCIEOBLE_01698 4.3e-92 batE T Sh3 type 3 domain protein
HCIEOBLE_01699 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HCIEOBLE_01700 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HCIEOBLE_01701 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HCIEOBLE_01702 5.8e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCIEOBLE_01703 8.4e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCIEOBLE_01704 7.9e-177 rbsR K transcriptional
HCIEOBLE_01705 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HCIEOBLE_01706 8.6e-70 pgsC S biosynthesis protein
HCIEOBLE_01707 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HCIEOBLE_01708 3.6e-21 ywtC
HCIEOBLE_01709 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HCIEOBLE_01710 9.1e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HCIEOBLE_01711 2.4e-170 ywtF K Transcriptional regulator
HCIEOBLE_01712 2.7e-247 ywtG EGP Major facilitator Superfamily
HCIEOBLE_01713 5.8e-208 gerAC S Spore germination protein
HCIEOBLE_01714 8.1e-194 gerBB E Spore germination protein
HCIEOBLE_01715 1.6e-263 gerBA EG Spore germination protein
HCIEOBLE_01716 2.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HCIEOBLE_01717 1.3e-213 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCIEOBLE_01718 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCIEOBLE_01719 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCIEOBLE_01720 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HCIEOBLE_01721 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HCIEOBLE_01722 1.7e-94 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HCIEOBLE_01723 2.4e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HCIEOBLE_01724 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HCIEOBLE_01725 5.3e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HCIEOBLE_01726 1.3e-111 ggaA M Glycosyltransferase like family 2
HCIEOBLE_01727 3.8e-88
HCIEOBLE_01728 2e-131 M Glycosyltransferase like family 2
HCIEOBLE_01729 3.9e-149 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCIEOBLE_01730 1e-132 tagG GM Transport permease protein
HCIEOBLE_01731 6.4e-269 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HCIEOBLE_01732 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HCIEOBLE_01733 3.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HCIEOBLE_01734 1.6e-99 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HCIEOBLE_01735 2.1e-88 M Glycosyltransferase like family 2
HCIEOBLE_01736 6.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCIEOBLE_01737 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HCIEOBLE_01738 1e-11
HCIEOBLE_01739 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HCIEOBLE_01740 5.9e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCIEOBLE_01741 2.5e-94 M Glycosyltransferase like family 2
HCIEOBLE_01742 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HCIEOBLE_01743 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCIEOBLE_01744 3.9e-215 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HCIEOBLE_01745 2.2e-257 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCIEOBLE_01746 4.5e-261 tuaE M Teichuronic acid biosynthesis protein
HCIEOBLE_01747 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
HCIEOBLE_01748 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HCIEOBLE_01749 8.6e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HCIEOBLE_01750 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HCIEOBLE_01751 5.9e-163 yvhJ K Transcriptional regulator
HCIEOBLE_01752 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HCIEOBLE_01753 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HCIEOBLE_01754 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCIEOBLE_01755 4.8e-154 degV S protein conserved in bacteria
HCIEOBLE_01756 1.5e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HCIEOBLE_01757 3.7e-45 comFB S Late competence development protein ComFB
HCIEOBLE_01758 6.8e-81 comFC S Phosphoribosyl transferase domain
HCIEOBLE_01759 6e-73 yvyF S flagellar protein
HCIEOBLE_01760 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
HCIEOBLE_01761 4.1e-78 flgN NOU FlgN protein
HCIEOBLE_01762 1.6e-264 flgK N flagellar hook-associated protein
HCIEOBLE_01763 7.8e-155 flgL N Belongs to the bacterial flagellin family
HCIEOBLE_01764 5.7e-50 yviE
HCIEOBLE_01765 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HCIEOBLE_01766 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HCIEOBLE_01767 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HCIEOBLE_01768 1.2e-52 flaG N flagellar protein FlaG
HCIEOBLE_01769 8.5e-247 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HCIEOBLE_01770 2.9e-69 fliS N flagellar protein FliS
HCIEOBLE_01771 1.9e-08 fliT S bacterial-type flagellum organization
HCIEOBLE_01772 4.6e-51
HCIEOBLE_01773 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCIEOBLE_01774 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCIEOBLE_01775 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCIEOBLE_01776 4.6e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HCIEOBLE_01777 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HCIEOBLE_01778 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HCIEOBLE_01779 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HCIEOBLE_01780 2.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HCIEOBLE_01781 5.3e-56 swrA S Swarming motility protein
HCIEOBLE_01782 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCIEOBLE_01783 3.3e-226 yvkA EGP Major facilitator Superfamily
HCIEOBLE_01784 1e-99 yvkB K Transcriptional regulator
HCIEOBLE_01785 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HCIEOBLE_01786 1.2e-30 csbA S protein conserved in bacteria
HCIEOBLE_01787 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCIEOBLE_01788 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCIEOBLE_01789 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HCIEOBLE_01790 1.3e-32 yvkN
HCIEOBLE_01791 8e-49 yvlA
HCIEOBLE_01792 9.2e-166 yvlB S Putative adhesin
HCIEOBLE_01793 2.6e-26 pspB KT PspC domain
HCIEOBLE_01794 1.2e-50 yvlD S Membrane
HCIEOBLE_01795 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HCIEOBLE_01796 9.9e-132 yvoA K transcriptional
HCIEOBLE_01797 9.8e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCIEOBLE_01798 1.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCIEOBLE_01799 6.4e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCIEOBLE_01800 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCIEOBLE_01801 1.7e-160 yvoD P COG0370 Fe2 transport system protein B
HCIEOBLE_01802 1.9e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HCIEOBLE_01803 1.5e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HCIEOBLE_01804 3.5e-120 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HCIEOBLE_01805 4.5e-140 yvpB NU protein conserved in bacteria
HCIEOBLE_01806 2.6e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HCIEOBLE_01807 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HCIEOBLE_01808 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCIEOBLE_01809 1.4e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HCIEOBLE_01810 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCIEOBLE_01811 1.3e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HCIEOBLE_01812 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCIEOBLE_01813 2.2e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HCIEOBLE_01814 3e-120
HCIEOBLE_01815 0.0
HCIEOBLE_01817 0.0 msbA2 3.6.3.44 V ABC transporter
HCIEOBLE_01818 2.5e-275 S COG0457 FOG TPR repeat
HCIEOBLE_01819 4.7e-98 usp CBM50 M protein conserved in bacteria
HCIEOBLE_01820 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCIEOBLE_01821 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HCIEOBLE_01822 5.7e-166 rapZ S Displays ATPase and GTPase activities
HCIEOBLE_01823 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HCIEOBLE_01824 4.1e-170 whiA K May be required for sporulation
HCIEOBLE_01825 1.6e-36 crh G Phosphocarrier protein Chr
HCIEOBLE_01826 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HCIEOBLE_01827 1.8e-33
HCIEOBLE_01828 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_01829 6.8e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HCIEOBLE_01830 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HCIEOBLE_01831 0.0 yxdM V ABC transporter (permease)
HCIEOBLE_01832 8.7e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIEOBLE_01833 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HCIEOBLE_01834 1.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HCIEOBLE_01835 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HCIEOBLE_01836 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
HCIEOBLE_01837 3.3e-172 yvdE K Transcriptional regulator
HCIEOBLE_01838 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HCIEOBLE_01839 4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HCIEOBLE_01840 1.7e-243 malC P COG1175 ABC-type sugar transport systems, permease components
HCIEOBLE_01841 3.3e-147 malD P transport
HCIEOBLE_01842 3.4e-155 malA S Protein of unknown function (DUF1189)
HCIEOBLE_01843 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HCIEOBLE_01844 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HCIEOBLE_01845 1.6e-112 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HCIEOBLE_01846 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCIEOBLE_01848 4e-173 S Patatin-like phospholipase
HCIEOBLE_01849 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
HCIEOBLE_01850 4.1e-50 sugE P Small Multidrug Resistance protein
HCIEOBLE_01851 3.3e-50 ykkC P Small Multidrug Resistance protein
HCIEOBLE_01852 9.7e-106 yvdT K Transcriptional regulator
HCIEOBLE_01853 1.8e-295 yveA E amino acid
HCIEOBLE_01854 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HCIEOBLE_01855 5.9e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HCIEOBLE_01856 1.7e-70
HCIEOBLE_01857 2.3e-259 pbpE V Beta-lactamase
HCIEOBLE_01858 1.7e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HCIEOBLE_01859 2.6e-74 MA20_18690 S Protein of unknown function (DUF3237)
HCIEOBLE_01860 5.1e-92 padC Q Phenolic acid decarboxylase
HCIEOBLE_01861 3.1e-278 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HCIEOBLE_01862 6.3e-76 slr K transcriptional
HCIEOBLE_01863 2e-121 ywqC M biosynthesis protein
HCIEOBLE_01864 2.3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HCIEOBLE_01865 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HCIEOBLE_01866 1.4e-217 epsD GT4 M Glycosyl transferase 4-like
HCIEOBLE_01867 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCIEOBLE_01868 1.6e-216 epsF GT4 M Glycosyl transferases group 1
HCIEOBLE_01869 5.4e-206 epsG S EpsG family
HCIEOBLE_01870 2e-194 epsH GT2 S Glycosyltransferase like family 2
HCIEOBLE_01871 4.4e-205 epsI GM pyruvyl transferase
HCIEOBLE_01872 1.2e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HCIEOBLE_01873 3.7e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCIEOBLE_01874 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HCIEOBLE_01875 1.2e-51 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HCIEOBLE_01876 1.5e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HCIEOBLE_01877 2.9e-187 yvfF GM Exopolysaccharide biosynthesis protein
HCIEOBLE_01878 1e-31 yvfG S YvfG protein
HCIEOBLE_01879 3.6e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HCIEOBLE_01880 6.3e-307 yvfH C L-lactate permease
HCIEOBLE_01881 1e-112 yvfI K COG2186 Transcriptional regulators
HCIEOBLE_01882 1.5e-183 lacR K Transcriptional regulator
HCIEOBLE_01883 4e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
HCIEOBLE_01884 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HCIEOBLE_01885 7.2e-150 ganQ P transport
HCIEOBLE_01886 0.0 lacA 3.2.1.23 G beta-galactosidase
HCIEOBLE_01887 3.7e-251 galA 3.2.1.89 G arabinogalactan
HCIEOBLE_01888 2.9e-197 rsbU 3.1.3.3 T response regulator
HCIEOBLE_01889 2.6e-157 rsbQ S Alpha/beta hydrolase family
HCIEOBLE_01890 8.9e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HCIEOBLE_01891 5.3e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
HCIEOBLE_01892 1.3e-196 desK 2.7.13.3 T Histidine kinase
HCIEOBLE_01893 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCIEOBLE_01894 4.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HCIEOBLE_01895 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HCIEOBLE_01896 2.4e-130 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HCIEOBLE_01897 3.7e-193 yvbX S Glycosyl hydrolase
HCIEOBLE_01898 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HCIEOBLE_01899 8.8e-154 yvbV EG EamA-like transporter family
HCIEOBLE_01900 3.3e-158 yvbU K Transcriptional regulator
HCIEOBLE_01901 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCIEOBLE_01902 1.2e-202 araR K transcriptional
HCIEOBLE_01903 3.7e-252 araE EGP Major facilitator Superfamily
HCIEOBLE_01904 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HCIEOBLE_01905 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCIEOBLE_01906 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HCIEOBLE_01907 2.8e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCIEOBLE_01908 8.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HCIEOBLE_01909 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCIEOBLE_01910 3.1e-165 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HCIEOBLE_01911 1.3e-217 1.1.1.136 M UDP binding domain
HCIEOBLE_01912 1.2e-184 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HCIEOBLE_01913 2.1e-147 5.1.3.2 M GDP-mannose 4,6 dehydratase
HCIEOBLE_01914 2e-153 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HCIEOBLE_01915 1.5e-114 M Protein involved in cellulose biosynthesis
HCIEOBLE_01916 6.4e-123 C WbqC-like protein family
HCIEOBLE_01917 2.3e-114 S GlcNAc-PI de-N-acetylase
HCIEOBLE_01918 3.1e-151
HCIEOBLE_01919 3.9e-173 EGP Major facilitator Superfamily
HCIEOBLE_01920 5e-81 yvbK 3.1.3.25 K acetyltransferase
HCIEOBLE_01921 0.0 tcaA S response to antibiotic
HCIEOBLE_01922 5.2e-122 exoY M Membrane
HCIEOBLE_01923 8.6e-113 yvbH S YvbH-like oligomerisation region
HCIEOBLE_01924 3.2e-102 yvbG U UPF0056 membrane protein
HCIEOBLE_01925 3.5e-97 yvbF K Belongs to the GbsR family
HCIEOBLE_01926 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HCIEOBLE_01927 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HCIEOBLE_01928 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCIEOBLE_01929 1.2e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HCIEOBLE_01930 1.7e-44 sdpR K transcriptional
HCIEOBLE_01931 3.1e-94 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HCIEOBLE_01932 4.4e-08
HCIEOBLE_01933 5.8e-172
HCIEOBLE_01934 7.9e-13 S Sporulation delaying protein SdpA
HCIEOBLE_01935 7.4e-60 yvbF K Belongs to the GbsR family
HCIEOBLE_01936 9.8e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HCIEOBLE_01937 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HCIEOBLE_01938 1.1e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCIEOBLE_01939 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HCIEOBLE_01940 6.5e-219 NT chemotaxis protein
HCIEOBLE_01941 2.2e-54 yodB K transcriptional
HCIEOBLE_01942 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
HCIEOBLE_01943 8.8e-69 K transcriptional
HCIEOBLE_01944 7.5e-36 yvzC K Transcriptional
HCIEOBLE_01945 5.9e-151 yvaM S Serine aminopeptidase, S33
HCIEOBLE_01946 2.4e-23 secG U Preprotein translocase subunit SecG
HCIEOBLE_01947 9.6e-143 est 3.1.1.1 S Carboxylesterase
HCIEOBLE_01948 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCIEOBLE_01949 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HCIEOBLE_01951 9.9e-86 S Protein of unknown function DUF262
HCIEOBLE_01952 2e-69 S AAA ATPase domain
HCIEOBLE_01953 2.6e-35
HCIEOBLE_01954 2.6e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEOBLE_01955 4.3e-98 K Bacterial regulatory proteins, tetR family
HCIEOBLE_01956 2e-53 yvaE P Small Multidrug Resistance protein
HCIEOBLE_01957 1.3e-72 yvaD S Family of unknown function (DUF5360)
HCIEOBLE_01958 0.0 yvaC S Fusaric acid resistance protein-like
HCIEOBLE_01959 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCIEOBLE_01960 4.5e-194 yvaA 1.1.1.371 S Oxidoreductase
HCIEOBLE_01961 2.2e-48 csoR S transcriptional
HCIEOBLE_01962 1.5e-29 copZ P Copper resistance protein CopZ
HCIEOBLE_01963 0.0 copA 3.6.3.54 P P-type ATPase
HCIEOBLE_01964 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HCIEOBLE_01965 1.6e-104 bdbD O Thioredoxin
HCIEOBLE_01966 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HCIEOBLE_01967 1.6e-106 yvgT S membrane
HCIEOBLE_01969 0.0 helD 3.6.4.12 L DNA helicase
HCIEOBLE_01970 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HCIEOBLE_01971 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HCIEOBLE_01972 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HCIEOBLE_01973 2.1e-85 yvgO
HCIEOBLE_01974 5.9e-157 yvgN S reductase
HCIEOBLE_01975 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
HCIEOBLE_01976 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HCIEOBLE_01977 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HCIEOBLE_01978 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HCIEOBLE_01979 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HCIEOBLE_01980 6.5e-16 S Small spore protein J (Spore_SspJ)
HCIEOBLE_01981 1.8e-235 yvsH E Arginine ornithine antiporter
HCIEOBLE_01982 9e-178 fhuD P ABC transporter
HCIEOBLE_01983 6.7e-182 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_01984 1.5e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_01985 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HCIEOBLE_01986 5.3e-175 M Efflux transporter rnd family, mfp subunit
HCIEOBLE_01987 1.6e-123 macB V ABC transporter, ATP-binding protein
HCIEOBLE_01988 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HCIEOBLE_01989 1.3e-64 yvrL S Regulatory protein YrvL
HCIEOBLE_01990 4e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
HCIEOBLE_01991 2.4e-19 S YvrJ protein family
HCIEOBLE_01992 9.5e-98 yvrI K RNA polymerase
HCIEOBLE_01993 3.6e-22
HCIEOBLE_01994 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_01995 0.0 T PhoQ Sensor
HCIEOBLE_01996 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HCIEOBLE_01997 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEOBLE_01998 5.8e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HCIEOBLE_01999 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_02000 1.3e-243 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HCIEOBLE_02001 1.4e-99 yvqK 2.5.1.17 S Adenosyltransferase
HCIEOBLE_02002 4.8e-227 yvqJ EGP Major facilitator Superfamily
HCIEOBLE_02003 8.1e-61 liaI S membrane
HCIEOBLE_02004 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HCIEOBLE_02005 2.1e-120 liaG S Putative adhesin
HCIEOBLE_02006 3.6e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HCIEOBLE_02007 7.9e-186 vraS 2.7.13.3 T Histidine kinase
HCIEOBLE_02008 6.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCIEOBLE_02009 2.6e-184 gerAC S Spore germination B3/ GerAC like, C-terminal
HCIEOBLE_02010 1.2e-194 gerAB E Spore germination protein
HCIEOBLE_02011 5.3e-246 gerAA EG Spore germination protein
HCIEOBLE_02012 2.3e-24 S Protein of unknown function (DUF3970)
HCIEOBLE_02013 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCIEOBLE_02014 1.3e-157 yuxN K Transcriptional regulator
HCIEOBLE_02015 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HCIEOBLE_02016 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_02017 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCIEOBLE_02018 2.7e-79 dps P Ferritin-like domain
HCIEOBLE_02019 3.2e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEOBLE_02020 1.8e-299 pepF2 E COG1164 Oligoendopeptidase F
HCIEOBLE_02021 1.1e-66 S YusW-like protein
HCIEOBLE_02022 1e-153 yusV 3.6.3.34 HP ABC transporter
HCIEOBLE_02023 3.8e-47 yusU S Protein of unknown function (DUF2573)
HCIEOBLE_02024 5.7e-158 yusT K LysR substrate binding domain
HCIEOBLE_02025 1.7e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEOBLE_02026 2.4e-65 yusQ S Tautomerase enzyme
HCIEOBLE_02027 8.5e-293 yusP P Major facilitator superfamily
HCIEOBLE_02028 2.6e-66 yusO K Iron dependent repressor, N-terminal DNA binding domain
HCIEOBLE_02029 5.4e-53 yusN M Coat F domain
HCIEOBLE_02030 5.1e-40
HCIEOBLE_02031 9.3e-164 fadM E Proline dehydrogenase
HCIEOBLE_02032 8.1e-09 S YuzL-like protein
HCIEOBLE_02033 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HCIEOBLE_02034 2.7e-216 fadA 2.3.1.16 I Belongs to the thiolase family
HCIEOBLE_02035 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HCIEOBLE_02036 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HCIEOBLE_02037 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HCIEOBLE_02038 1.1e-39 yusG S Protein of unknown function (DUF2553)
HCIEOBLE_02039 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HCIEOBLE_02040 5.6e-55 traF CO Thioredoxin
HCIEOBLE_02041 2.4e-56 yusD S SCP-2 sterol transfer family
HCIEOBLE_02042 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCIEOBLE_02043 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HCIEOBLE_02044 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
HCIEOBLE_02045 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HCIEOBLE_02046 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HCIEOBLE_02047 1.4e-245 sufD O assembly protein SufD
HCIEOBLE_02048 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCIEOBLE_02049 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HCIEOBLE_02050 3.5e-271 sufB O FeS cluster assembly
HCIEOBLE_02051 1.3e-63 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCIEOBLE_02052 1e-41
HCIEOBLE_02054 8.4e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HCIEOBLE_02055 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HCIEOBLE_02056 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HCIEOBLE_02057 9.4e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HCIEOBLE_02058 2e-155 yurN G Binding-protein-dependent transport system inner membrane component
HCIEOBLE_02059 1.6e-168 yurM P COG0395 ABC-type sugar transport system, permease component
HCIEOBLE_02060 4.8e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HCIEOBLE_02061 4.3e-135 yurK K UTRA
HCIEOBLE_02062 8.5e-204 msmX P Belongs to the ABC transporter superfamily
HCIEOBLE_02063 3.5e-168 bsn L Ribonuclease
HCIEOBLE_02064 1.7e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HCIEOBLE_02065 1e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HCIEOBLE_02066 1.2e-183 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HCIEOBLE_02067 1.3e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HCIEOBLE_02068 4.4e-144 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HCIEOBLE_02069 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HCIEOBLE_02070 4.8e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HCIEOBLE_02073 3.2e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HCIEOBLE_02074 1.2e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HCIEOBLE_02075 3.7e-222 pbuX F xanthine
HCIEOBLE_02076 1.5e-231 pbuX F Permease family
HCIEOBLE_02077 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
HCIEOBLE_02078 8.6e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HCIEOBLE_02079 6.9e-59 yunG
HCIEOBLE_02080 4.3e-171 yunF S Protein of unknown function DUF72
HCIEOBLE_02081 1e-140 yunE S membrane transporter protein
HCIEOBLE_02082 1.9e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HCIEOBLE_02083 3.1e-47 yunC S Domain of unknown function (DUF1805)
HCIEOBLE_02084 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
HCIEOBLE_02085 2.9e-195 lytH M Peptidase, M23
HCIEOBLE_02086 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HCIEOBLE_02087 4.1e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCIEOBLE_02088 9.7e-48 yutD S protein conserved in bacteria
HCIEOBLE_02089 2.5e-74 yutE S Protein of unknown function DUF86
HCIEOBLE_02090 4.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCIEOBLE_02091 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HCIEOBLE_02092 3.8e-198 yutH S Spore coat protein
HCIEOBLE_02093 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
HCIEOBLE_02094 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HCIEOBLE_02095 3.3e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCIEOBLE_02096 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HCIEOBLE_02097 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HCIEOBLE_02098 3e-56 yuzD S protein conserved in bacteria
HCIEOBLE_02099 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HCIEOBLE_02100 3.2e-39 yuzB S Belongs to the UPF0349 family
HCIEOBLE_02101 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HCIEOBLE_02102 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCIEOBLE_02103 3.7e-63 erpA S Belongs to the HesB IscA family
HCIEOBLE_02104 9.6e-73 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCIEOBLE_02105 1.9e-115 paiB K Putative FMN-binding domain
HCIEOBLE_02106 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCIEOBLE_02108 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HCIEOBLE_02109 2.7e-235 yumB 1.6.99.3 C NADH dehydrogenase
HCIEOBLE_02110 1.1e-26 yuiB S Putative membrane protein
HCIEOBLE_02111 2.1e-117 yuiC S protein conserved in bacteria
HCIEOBLE_02112 1.2e-77 yuiD S protein conserved in bacteria
HCIEOBLE_02113 2.2e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HCIEOBLE_02114 3.9e-211 yuiF S antiporter
HCIEOBLE_02115 4.4e-93 bioY S Biotin biosynthesis protein
HCIEOBLE_02116 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HCIEOBLE_02117 1.5e-166 besA S Putative esterase
HCIEOBLE_02118 1.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEOBLE_02119 4.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
HCIEOBLE_02120 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HCIEOBLE_02121 2.1e-174 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HCIEOBLE_02122 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIEOBLE_02123 8.5e-36 mbtH S MbtH-like protein
HCIEOBLE_02124 3.5e-131 yukJ S Uncharacterized conserved protein (DUF2278)
HCIEOBLE_02125 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HCIEOBLE_02126 1.9e-228 yukF QT Transcriptional regulator
HCIEOBLE_02127 2.8e-45 esxA S Belongs to the WXG100 family
HCIEOBLE_02128 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HCIEOBLE_02129 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HCIEOBLE_02130 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HCIEOBLE_02131 0.0 esaA S type VII secretion protein EsaA
HCIEOBLE_02132 3.3e-64 yueC S Family of unknown function (DUF5383)
HCIEOBLE_02133 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEOBLE_02134 4.8e-96 yueE S phosphohydrolase
HCIEOBLE_02135 2.9e-24 S Protein of unknown function (DUF2642)
HCIEOBLE_02136 1.5e-70 S Protein of unknown function (DUF2283)
HCIEOBLE_02137 5.4e-190 yueF S transporter activity
HCIEOBLE_02138 6.6e-31 yueG S Spore germination protein gerPA/gerPF
HCIEOBLE_02139 2.8e-38 yueH S YueH-like protein
HCIEOBLE_02140 7.9e-67 yueI S Protein of unknown function (DUF1694)
HCIEOBLE_02141 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
HCIEOBLE_02142 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCIEOBLE_02143 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HCIEOBLE_02144 1.9e-22 yuzC
HCIEOBLE_02146 3.5e-137 comQ H Belongs to the FPP GGPP synthase family
HCIEOBLE_02148 0.0 comP 2.7.13.3 T Histidine kinase
HCIEOBLE_02149 2.3e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCIEOBLE_02150 4.6e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
HCIEOBLE_02151 2.8e-58 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HCIEOBLE_02152 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCIEOBLE_02153 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCIEOBLE_02154 4.2e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCIEOBLE_02155 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCIEOBLE_02156 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCIEOBLE_02157 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HCIEOBLE_02158 5e-15
HCIEOBLE_02159 8.2e-233 maeN C COG3493 Na citrate symporter
HCIEOBLE_02160 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HCIEOBLE_02161 9.3e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HCIEOBLE_02162 1.3e-271 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HCIEOBLE_02163 1.7e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HCIEOBLE_02164 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HCIEOBLE_02165 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HCIEOBLE_02166 6.3e-78 yufK S Family of unknown function (DUF5366)
HCIEOBLE_02167 1.8e-74 yuxK S protein conserved in bacteria
HCIEOBLE_02168 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HCIEOBLE_02169 2.7e-183 yuxJ EGP Major facilitator Superfamily
HCIEOBLE_02171 1.9e-115 kapD L the KinA pathway to sporulation
HCIEOBLE_02172 4.8e-69 kapB G Kinase associated protein B
HCIEOBLE_02173 4.6e-233 T PhoQ Sensor
HCIEOBLE_02174 5.8e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HCIEOBLE_02175 4.6e-39 yugE S Domain of unknown function (DUF1871)
HCIEOBLE_02176 9.3e-155 yugF I Hydrolase
HCIEOBLE_02177 1.6e-85 alaR K Transcriptional regulator
HCIEOBLE_02178 2.1e-199 yugH 2.6.1.1 E Aminotransferase
HCIEOBLE_02179 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HCIEOBLE_02180 1.1e-34 yuzA S Domain of unknown function (DUF378)
HCIEOBLE_02181 3.4e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HCIEOBLE_02182 2.8e-229 yugK C Dehydrogenase
HCIEOBLE_02183 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HCIEOBLE_02185 1.3e-72 yugN S YugN-like family
HCIEOBLE_02186 7e-181 yugO P COG1226 Kef-type K transport systems
HCIEOBLE_02187 1.1e-53 mstX S Membrane-integrating protein Mistic
HCIEOBLE_02188 2.3e-38
HCIEOBLE_02189 1.4e-116 yugP S Zn-dependent protease
HCIEOBLE_02190 4.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HCIEOBLE_02191 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HCIEOBLE_02192 1.1e-71 yugU S Uncharacterised protein family UPF0047
HCIEOBLE_02193 1.8e-35
HCIEOBLE_02194 4.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HCIEOBLE_02195 3.5e-224 mcpA NT chemotaxis protein
HCIEOBLE_02196 6.9e-215 mcpA NT chemotaxis protein
HCIEOBLE_02198 5.5e-294 mcpA NT chemotaxis protein
HCIEOBLE_02199 7.3e-238 mcpA NT chemotaxis protein
HCIEOBLE_02200 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HCIEOBLE_02201 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HCIEOBLE_02202 8.8e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HCIEOBLE_02203 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HCIEOBLE_02204 2e-249 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HCIEOBLE_02205 3.3e-183 ygjR S Oxidoreductase
HCIEOBLE_02206 3.7e-189 yubA S transporter activity
HCIEOBLE_02207 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCIEOBLE_02209 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HCIEOBLE_02210 2.2e-274 yubD P Major Facilitator Superfamily
HCIEOBLE_02211 3.2e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCIEOBLE_02212 1e-38 yiaA S yiaA/B two helix domain
HCIEOBLE_02213 2.1e-236 ktrB P Potassium
HCIEOBLE_02214 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HCIEOBLE_02215 2.2e-91 yuaB
HCIEOBLE_02216 5.5e-95 yuaC K Belongs to the GbsR family
HCIEOBLE_02217 2e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HCIEOBLE_02218 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HCIEOBLE_02219 5.6e-106 yuaD
HCIEOBLE_02220 3.9e-84 yuaE S DinB superfamily
HCIEOBLE_02221 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HCIEOBLE_02222 3.5e-187 yuaG 3.4.21.72 S protein conserved in bacteria
HCIEOBLE_02223 1.7e-93 M1-753 M FR47-like protein
HCIEOBLE_02224 1.1e-88 thiT S Thiamine transporter protein (Thia_YuaJ)
HCIEOBLE_02227 1.3e-09
HCIEOBLE_02228 7.8e-08
HCIEOBLE_02237 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCIEOBLE_02238 4e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCIEOBLE_02239 2.2e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HCIEOBLE_02240 3.1e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HCIEOBLE_02241 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCIEOBLE_02242 1.4e-75 tspO T membrane
HCIEOBLE_02243 1.4e-203 cotI S Spore coat protein
HCIEOBLE_02244 1.8e-217 cotSA M Glycosyl transferases group 1
HCIEOBLE_02245 2.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
HCIEOBLE_02247 1e-234 ytcC M Glycosyltransferase Family 4
HCIEOBLE_02248 1.7e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HCIEOBLE_02249 7.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCIEOBLE_02250 2.3e-153 galU 2.7.7.9 M Nucleotidyl transferase
HCIEOBLE_02251 1.3e-131 dksA T COG1734 DnaK suppressor protein
HCIEOBLE_02252 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
HCIEOBLE_02253 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HCIEOBLE_02254 1.4e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HCIEOBLE_02255 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HCIEOBLE_02256 1.3e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HCIEOBLE_02257 1.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HCIEOBLE_02258 1.7e-168 troA P Belongs to the bacterial solute-binding protein 9 family
HCIEOBLE_02259 7.3e-138 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HCIEOBLE_02260 1.5e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HCIEOBLE_02261 9.7e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HCIEOBLE_02262 1.1e-24 S Domain of Unknown Function (DUF1540)
HCIEOBLE_02263 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HCIEOBLE_02264 8.9e-248 cydA 1.10.3.14 C oxidase, subunit
HCIEOBLE_02265 3.6e-41 rpmE2 J Ribosomal protein L31
HCIEOBLE_02266 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HCIEOBLE_02267 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCIEOBLE_02268 2.4e-72 ytkA S YtkA-like
HCIEOBLE_02270 2.1e-76 dps P Belongs to the Dps family
HCIEOBLE_02271 7.8e-62 ytkC S Bacteriophage holin family
HCIEOBLE_02272 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HCIEOBLE_02273 1.2e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCIEOBLE_02274 1.4e-144 ytlC P ABC transporter
HCIEOBLE_02275 3.6e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HCIEOBLE_02276 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HCIEOBLE_02277 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HCIEOBLE_02278 2.6e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HCIEOBLE_02279 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCIEOBLE_02280 0.0 asnB 6.3.5.4 E Asparagine synthase
HCIEOBLE_02281 2.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HCIEOBLE_02282 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HCIEOBLE_02283 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HCIEOBLE_02284 9.8e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HCIEOBLE_02285 3.7e-105 ytqB J Putative rRNA methylase
HCIEOBLE_02286 1.8e-189 yhcC S Fe-S oxidoreductase
HCIEOBLE_02287 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HCIEOBLE_02289 5.1e-66 ytrA K GntR family transcriptional regulator
HCIEOBLE_02290 1.6e-160 ytrB P abc transporter atp-binding protein
HCIEOBLE_02291 4.7e-153 P ABC-2 family transporter protein
HCIEOBLE_02292 1.3e-147
HCIEOBLE_02293 9.1e-127 ytrE V ABC transporter, ATP-binding protein
HCIEOBLE_02294 1.9e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HCIEOBLE_02295 5.8e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_02296 1.6e-185 T PhoQ Sensor
HCIEOBLE_02297 7.3e-138 bceA V ABC transporter, ATP-binding protein
HCIEOBLE_02298 0.0 bceB V ABC transporter (permease)
HCIEOBLE_02299 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HCIEOBLE_02300 1e-210 yttB EGP Major facilitator Superfamily
HCIEOBLE_02301 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HCIEOBLE_02302 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HCIEOBLE_02303 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCIEOBLE_02304 2.1e-51 ytwF P Sulfurtransferase
HCIEOBLE_02305 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HCIEOBLE_02306 4.4e-144 amyC P ABC transporter (permease)
HCIEOBLE_02307 6.2e-168 amyD P ABC transporter
HCIEOBLE_02308 8e-246 msmE G Bacterial extracellular solute-binding protein
HCIEOBLE_02309 6.2e-188 msmR K Transcriptional regulator
HCIEOBLE_02310 3.2e-172 ytaP S Acetyl xylan esterase (AXE1)
HCIEOBLE_02311 8.1e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HCIEOBLE_02312 2.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HCIEOBLE_02313 3e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HCIEOBLE_02314 3e-122 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HCIEOBLE_02315 1e-187 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HCIEOBLE_02316 2.2e-221 bioI 1.14.14.46 C Cytochrome P450
HCIEOBLE_02317 2.1e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HCIEOBLE_02318 2e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HCIEOBLE_02319 8.9e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HCIEOBLE_02320 0.0 ytdP K Transcriptional regulator
HCIEOBLE_02321 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HCIEOBLE_02322 5.2e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HCIEOBLE_02323 1.7e-72 yteS G transport
HCIEOBLE_02324 1.3e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HCIEOBLE_02325 1.9e-113 yteU S Integral membrane protein
HCIEOBLE_02326 3.1e-26 yteV S Sporulation protein Cse60
HCIEOBLE_02327 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HCIEOBLE_02328 2e-230 ytfP S HI0933-like protein
HCIEOBLE_02329 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCIEOBLE_02330 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCIEOBLE_02331 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HCIEOBLE_02332 1.8e-130 ythP V ABC transporter
HCIEOBLE_02333 2.1e-205 ythQ U Bacterial ABC transporter protein EcsB
HCIEOBLE_02334 2.1e-225 pbuO S permease
HCIEOBLE_02335 5.6e-269 pepV 3.5.1.18 E Dipeptidase
HCIEOBLE_02336 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HCIEOBLE_02337 6.1e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HCIEOBLE_02338 1.3e-165 ytlQ
HCIEOBLE_02339 1.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HCIEOBLE_02340 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HCIEOBLE_02341 7.9e-151 ytmP 2.7.1.89 M Phosphotransferase
HCIEOBLE_02342 2e-45 ytzH S YtzH-like protein
HCIEOBLE_02343 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCIEOBLE_02344 2.4e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HCIEOBLE_02345 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HCIEOBLE_02346 2.2e-51 ytzB S small secreted protein
HCIEOBLE_02347 1.2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HCIEOBLE_02348 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HCIEOBLE_02349 1.3e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HCIEOBLE_02350 9.8e-149 ytpQ S Belongs to the UPF0354 family
HCIEOBLE_02351 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCIEOBLE_02352 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HCIEOBLE_02353 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HCIEOBLE_02354 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCIEOBLE_02355 6.6e-17 ytxH S COG4980 Gas vesicle protein
HCIEOBLE_02356 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
HCIEOBLE_02357 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HCIEOBLE_02358 3.8e-182 ccpA K catabolite control protein A
HCIEOBLE_02359 2.1e-146 motA N flagellar motor
HCIEOBLE_02360 5.2e-125 motS N Flagellar motor protein
HCIEOBLE_02361 3.5e-224 acuC BQ histone deacetylase
HCIEOBLE_02362 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HCIEOBLE_02363 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HCIEOBLE_02364 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HCIEOBLE_02365 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCIEOBLE_02367 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCIEOBLE_02368 2.4e-311 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HCIEOBLE_02369 5.9e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HCIEOBLE_02370 1e-108 yttP K Transcriptional regulator
HCIEOBLE_02371 5.9e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HCIEOBLE_02372 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCIEOBLE_02373 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HCIEOBLE_02374 3.5e-208 iscS2 2.8.1.7 E Cysteine desulfurase
HCIEOBLE_02375 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCIEOBLE_02376 2e-29 sspB S spore protein
HCIEOBLE_02377 2.3e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HCIEOBLE_02378 0.0 ytcJ S amidohydrolase
HCIEOBLE_02379 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCIEOBLE_02380 5.1e-179 sppA OU signal peptide peptidase SppA
HCIEOBLE_02381 8.5e-87 yteJ S RDD family
HCIEOBLE_02382 5.6e-116 ytfI S Protein of unknown function (DUF2953)
HCIEOBLE_02383 8.7e-70 ytfJ S Sporulation protein YtfJ
HCIEOBLE_02384 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCIEOBLE_02385 1.3e-163 ytxK 2.1.1.72 L DNA methylase
HCIEOBLE_02386 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCIEOBLE_02387 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HCIEOBLE_02388 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCIEOBLE_02389 4.9e-265 argH 4.3.2.1 E argininosuccinate lyase
HCIEOBLE_02391 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEOBLE_02392 1.7e-130 ytkL S Belongs to the UPF0173 family
HCIEOBLE_02393 1.9e-172 ytlI K LysR substrate binding domain
HCIEOBLE_02394 1.6e-99 ytmI K Acetyltransferase (GNAT) domain
HCIEOBLE_02395 1.4e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
HCIEOBLE_02396 2.2e-148 tcyK M Bacterial periplasmic substrate-binding proteins
HCIEOBLE_02397 7e-122 tcyL P Binding-protein-dependent transport system inner membrane component
HCIEOBLE_02398 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
HCIEOBLE_02399 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCIEOBLE_02400 1.5e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCIEOBLE_02401 1.9e-46 ytnI O COG0695 Glutaredoxin and related proteins
HCIEOBLE_02402 2.6e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCIEOBLE_02403 6.9e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HCIEOBLE_02404 1.9e-236 ytnL 3.5.1.47 E hydrolase activity
HCIEOBLE_02405 1.1e-156 ytnM S membrane transporter protein
HCIEOBLE_02406 5.2e-240 ytoI K transcriptional regulator containing CBS domains
HCIEOBLE_02407 2.4e-47 ytpI S YtpI-like protein
HCIEOBLE_02408 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HCIEOBLE_02409 9.2e-29
HCIEOBLE_02410 8.2e-69 ytrI
HCIEOBLE_02411 3.2e-56 ytrH S Sporulation protein YtrH
HCIEOBLE_02412 0.0 dnaE 2.7.7.7 L DNA polymerase
HCIEOBLE_02413 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HCIEOBLE_02414 1.2e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCIEOBLE_02415 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HCIEOBLE_02416 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCIEOBLE_02417 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HCIEOBLE_02418 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HCIEOBLE_02419 3.4e-192 ytvI S sporulation integral membrane protein YtvI
HCIEOBLE_02420 1.1e-70 yeaL S membrane
HCIEOBLE_02421 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HCIEOBLE_02422 4.1e-242 icd 1.1.1.42 C isocitrate
HCIEOBLE_02423 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HCIEOBLE_02424 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_02425 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HCIEOBLE_02426 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCIEOBLE_02427 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCIEOBLE_02428 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HCIEOBLE_02429 1.4e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCIEOBLE_02430 8.9e-161 ytbE S reductase
HCIEOBLE_02431 7.1e-204 ytbD EGP Major facilitator Superfamily
HCIEOBLE_02432 9.9e-67 ytcD K Transcriptional regulator
HCIEOBLE_02433 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCIEOBLE_02434 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HCIEOBLE_02435 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCIEOBLE_02436 1.5e-264 dnaB L Membrane attachment protein
HCIEOBLE_02437 9.5e-172 dnaI L Primosomal protein DnaI
HCIEOBLE_02438 9.6e-107 ytxB S SNARE associated Golgi protein
HCIEOBLE_02439 1.4e-158 ytxC S YtxC-like family
HCIEOBLE_02441 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCIEOBLE_02442 7.3e-149 ysaA S HAD-hyrolase-like
HCIEOBLE_02443 0.0 lytS 2.7.13.3 T Histidine kinase
HCIEOBLE_02444 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HCIEOBLE_02445 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HCIEOBLE_02446 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HCIEOBLE_02448 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCIEOBLE_02449 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HCIEOBLE_02450 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCIEOBLE_02451 7.5e-45 ysdA S Membrane
HCIEOBLE_02452 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HCIEOBLE_02453 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
HCIEOBLE_02454 4.6e-185 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HCIEOBLE_02455 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HCIEOBLE_02456 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HCIEOBLE_02457 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HCIEOBLE_02458 5e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HCIEOBLE_02459 7.5e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HCIEOBLE_02460 9e-253 araN G carbohydrate transport
HCIEOBLE_02461 4.2e-167 araP G carbohydrate transport
HCIEOBLE_02462 1.9e-142 araQ G transport system permease
HCIEOBLE_02463 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HCIEOBLE_02464 0.0 cstA T Carbon starvation protein
HCIEOBLE_02465 3.4e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
HCIEOBLE_02466 3.1e-256 glcF C Glycolate oxidase
HCIEOBLE_02467 2.4e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
HCIEOBLE_02468 1.1e-203 ysfB KT regulator
HCIEOBLE_02469 5.8e-32 sspI S Belongs to the SspI family
HCIEOBLE_02470 5.9e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCIEOBLE_02471 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCIEOBLE_02472 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCIEOBLE_02473 1.7e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCIEOBLE_02474 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HCIEOBLE_02475 1.7e-85 cvpA S membrane protein, required for colicin V production
HCIEOBLE_02476 0.0 polX L COG1796 DNA polymerase IV (family X)
HCIEOBLE_02477 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCIEOBLE_02478 7.3e-68 yshE S membrane
HCIEOBLE_02479 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCIEOBLE_02480 1.1e-98 fadR K Transcriptional regulator
HCIEOBLE_02481 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HCIEOBLE_02482 6.5e-134 etfB C Electron transfer flavoprotein
HCIEOBLE_02483 1.8e-176 etfA C Electron transfer flavoprotein
HCIEOBLE_02485 4.1e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HCIEOBLE_02486 2e-52 trxA O Belongs to the thioredoxin family
HCIEOBLE_02487 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCIEOBLE_02488 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HCIEOBLE_02489 1.2e-79 yslB S Protein of unknown function (DUF2507)
HCIEOBLE_02490 2.4e-107 sdhC C succinate dehydrogenase
HCIEOBLE_02491 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HCIEOBLE_02492 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HCIEOBLE_02493 5.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HCIEOBLE_02494 3.3e-30 gerE K Transcriptional regulator
HCIEOBLE_02495 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HCIEOBLE_02496 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HCIEOBLE_02497 2.9e-196 gerM S COG5401 Spore germination protein
HCIEOBLE_02498 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HCIEOBLE_02499 1.7e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCIEOBLE_02500 4.1e-92 ysnB S Phosphoesterase
HCIEOBLE_02502 2.9e-132 ysnF S protein conserved in bacteria
HCIEOBLE_02503 1.1e-120 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HCIEOBLE_02504 5.4e-75 ysnE K acetyltransferase
HCIEOBLE_02506 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HCIEOBLE_02507 9.3e-84 ilvN 2.2.1.6 E Acetolactate synthase
HCIEOBLE_02508 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HCIEOBLE_02509 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HCIEOBLE_02510 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HCIEOBLE_02511 3.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCIEOBLE_02512 9e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCIEOBLE_02513 1.1e-186 ysoA H Tetratricopeptide repeat
HCIEOBLE_02514 1.4e-221 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCIEOBLE_02515 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCIEOBLE_02516 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HCIEOBLE_02517 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HCIEOBLE_02518 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HCIEOBLE_02519 1.4e-89 ysxD
HCIEOBLE_02520 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HCIEOBLE_02521 3.6e-146 hemX O cytochrome C
HCIEOBLE_02522 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HCIEOBLE_02523 1.2e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HCIEOBLE_02524 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HCIEOBLE_02525 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HCIEOBLE_02526 1.9e-202 spoVID M stage VI sporulation protein D
HCIEOBLE_02527 3.9e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HCIEOBLE_02528 1.6e-25
HCIEOBLE_02529 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCIEOBLE_02530 1.4e-245 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HCIEOBLE_02531 1.4e-125 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HCIEOBLE_02532 4.1e-165 spoIIB S Sporulation related domain
HCIEOBLE_02533 2.8e-102 maf D septum formation protein Maf
HCIEOBLE_02534 5.9e-126 radC E Belongs to the UPF0758 family
HCIEOBLE_02535 1.8e-184 mreB D Rod shape-determining protein MreB
HCIEOBLE_02536 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HCIEOBLE_02537 1.4e-84 mreD M shape-determining protein
HCIEOBLE_02538 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HCIEOBLE_02539 4.7e-143 minD D Belongs to the ParA family
HCIEOBLE_02540 1.9e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HCIEOBLE_02541 9.2e-161 spoIVFB S Stage IV sporulation protein
HCIEOBLE_02542 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HCIEOBLE_02543 4.1e-56 ysxB J ribosomal protein
HCIEOBLE_02544 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HCIEOBLE_02545 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HCIEOBLE_02546 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCIEOBLE_02547 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HCIEOBLE_02548 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
HCIEOBLE_02549 3.9e-93 niaR S small molecule binding protein (contains 3H domain)
HCIEOBLE_02550 3.5e-227 nifS 2.8.1.7 E Cysteine desulfurase
HCIEOBLE_02551 3.4e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HCIEOBLE_02552 3.1e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HCIEOBLE_02553 4.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HCIEOBLE_02554 4.8e-157 safA M spore coat assembly protein SafA
HCIEOBLE_02555 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCIEOBLE_02556 3.6e-126 yebC K transcriptional regulatory protein
HCIEOBLE_02557 4.5e-261 alsT E Sodium alanine symporter
HCIEOBLE_02559 1.6e-117 yrzF T serine threonine protein kinase
HCIEOBLE_02560 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HCIEOBLE_02561 1.5e-252 csbX EGP Major facilitator Superfamily
HCIEOBLE_02562 4.8e-93 bofC S BofC C-terminal domain
HCIEOBLE_02563 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCIEOBLE_02564 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCIEOBLE_02565 6.9e-19 yrzS S Protein of unknown function (DUF2905)
HCIEOBLE_02566 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCIEOBLE_02567 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCIEOBLE_02568 8e-39 yajC U Preprotein translocase subunit YajC
HCIEOBLE_02569 1.2e-74 yrzE S Protein of unknown function (DUF3792)
HCIEOBLE_02570 1.9e-113 yrbG S membrane
HCIEOBLE_02571 1.7e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCIEOBLE_02572 1.6e-48 yrzD S Post-transcriptional regulator
HCIEOBLE_02573 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HCIEOBLE_02574 6.6e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HCIEOBLE_02575 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HCIEOBLE_02576 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HCIEOBLE_02577 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCIEOBLE_02578 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCIEOBLE_02579 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCIEOBLE_02580 3.1e-260 lytH 3.5.1.28 M COG3103 SH3 domain protein
HCIEOBLE_02582 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HCIEOBLE_02583 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HCIEOBLE_02584 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HCIEOBLE_02585 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HCIEOBLE_02586 1.2e-70 cymR K Transcriptional regulator
HCIEOBLE_02587 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
HCIEOBLE_02588 5.6e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCIEOBLE_02589 1.4e-15 S COG0457 FOG TPR repeat
HCIEOBLE_02590 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCIEOBLE_02591 1.7e-81 yrrD S protein conserved in bacteria
HCIEOBLE_02592 9.8e-31 yrzR
HCIEOBLE_02593 1.4e-07 S Protein of unknown function (DUF3918)
HCIEOBLE_02594 7.6e-107 glnP P ABC transporter
HCIEOBLE_02595 4e-108 gluC P ABC transporter
HCIEOBLE_02596 4.3e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
HCIEOBLE_02597 5.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCIEOBLE_02598 2.7e-170 yrrI S AI-2E family transporter
HCIEOBLE_02599 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCIEOBLE_02600 1.7e-41 yrzL S Belongs to the UPF0297 family
HCIEOBLE_02601 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCIEOBLE_02602 1.2e-45 yrzB S Belongs to the UPF0473 family
HCIEOBLE_02603 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCIEOBLE_02604 3.8e-119 yrrM 2.1.1.104 S O-methyltransferase
HCIEOBLE_02605 2.9e-173 yegQ O Peptidase U32
HCIEOBLE_02606 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HCIEOBLE_02607 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HCIEOBLE_02608 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCIEOBLE_02609 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HCIEOBLE_02610 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HCIEOBLE_02611 1e-25 yrzA S Protein of unknown function (DUF2536)
HCIEOBLE_02612 1.9e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HCIEOBLE_02613 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCIEOBLE_02614 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HCIEOBLE_02615 1.8e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HCIEOBLE_02616 4.6e-35 yrhC S YrhC-like protein
HCIEOBLE_02617 5.4e-78 yrhD S Protein of unknown function (DUF1641)
HCIEOBLE_02618 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HCIEOBLE_02619 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HCIEOBLE_02620 1.8e-142 focA P Formate nitrite
HCIEOBLE_02622 7.2e-95 yrhH Q methyltransferase
HCIEOBLE_02623 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HCIEOBLE_02624 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HCIEOBLE_02625 9.1e-44 yrhK S YrhK-like protein
HCIEOBLE_02626 0.0 yrhL I Acyltransferase family
HCIEOBLE_02627 4.7e-149 rsiV S Protein of unknown function (DUF3298)
HCIEOBLE_02628 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HCIEOBLE_02629 2.6e-149 yrhO K Archaeal transcriptional regulator TrmB
HCIEOBLE_02630 1.1e-105 yrhP E LysE type translocator
HCIEOBLE_02631 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HCIEOBLE_02632 0.0 levR K PTS system fructose IIA component
HCIEOBLE_02633 1.5e-74 levD 2.7.1.202 G PTS system fructose IIA component
HCIEOBLE_02634 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HCIEOBLE_02635 2.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HCIEOBLE_02636 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HCIEOBLE_02637 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HCIEOBLE_02638 8.5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HCIEOBLE_02639 8.7e-198 adhA 1.1.1.1 C alcohol dehydrogenase
HCIEOBLE_02640 1.6e-25 yphJ 4.1.1.44 S peroxiredoxin activity
HCIEOBLE_02641 4.3e-47 yraB K helix_turn_helix, mercury resistance
HCIEOBLE_02642 1.1e-47 yraD M Spore coat protein
HCIEOBLE_02643 7.5e-26 yraE
HCIEOBLE_02644 5.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HCIEOBLE_02645 6.4e-63 yraF M Spore coat protein
HCIEOBLE_02646 1.5e-36 yraG
HCIEOBLE_02647 2.1e-64 E Glyoxalase-like domain
HCIEOBLE_02648 5.4e-61 T sh3 domain protein
HCIEOBLE_02649 2.2e-60 T sh3 domain protein
HCIEOBLE_02650 1e-148 S Alpha beta hydrolase
HCIEOBLE_02651 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCIEOBLE_02652 8.5e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HCIEOBLE_02653 3.8e-187 yrpG C Aldo/keto reductase family
HCIEOBLE_02654 3.3e-92 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HCIEOBLE_02655 2.3e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HCIEOBLE_02656 5.6e-50 yjbR S YjbR
HCIEOBLE_02657 7.2e-118 bmrR K helix_turn_helix, mercury resistance
HCIEOBLE_02658 1.9e-98 flr S Flavin reductase like domain
HCIEOBLE_02659 1.6e-123 yrpD S Domain of unknown function, YrpD
HCIEOBLE_02660 8.5e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HCIEOBLE_02661 4.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HCIEOBLE_02662 5.5e-166 aadK G Streptomycin adenylyltransferase
HCIEOBLE_02663 6.4e-90 yrdA S DinB family
HCIEOBLE_02665 4e-55 S Protein of unknown function (DUF2568)
HCIEOBLE_02666 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
HCIEOBLE_02668 5.5e-74 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
HCIEOBLE_02669 3.9e-147 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
HCIEOBLE_02670 6.7e-252 cscA 3.2.1.26 GH32 G invertase
HCIEOBLE_02671 2.1e-198 rafB P LacY proton/sugar symporter
HCIEOBLE_02672 4.3e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
HCIEOBLE_02673 3.9e-149 msmF P Binding-protein-dependent transport system inner membrane component
HCIEOBLE_02674 1.3e-227 msmE G Bacterial extracellular solute-binding protein
HCIEOBLE_02675 1.2e-164 scrR K transcriptional
HCIEOBLE_02676 7.9e-65 K Transcriptional regulator
HCIEOBLE_02677 3.2e-39 K Acetyltransferase (GNAT) family
HCIEOBLE_02678 4.6e-222 cypA C Cytochrome P450
HCIEOBLE_02679 8.3e-24 yrdF K ribonuclease inhibitor
HCIEOBLE_02680 6.3e-79 bkdR K helix_turn_helix ASNC type
HCIEOBLE_02681 1.8e-136 azlC E AzlC protein
HCIEOBLE_02682 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HCIEOBLE_02683 3.2e-229 brnQ E Component of the transport system for branched-chain amino acids
HCIEOBLE_02684 1.3e-51 C COG2041 Sulfite oxidase and related enzymes
HCIEOBLE_02685 4.2e-161 gltR K LysR substrate binding domain
HCIEOBLE_02686 6.5e-66 yodA S tautomerase
HCIEOBLE_02687 7e-146 czcD P COG1230 Co Zn Cd efflux system component
HCIEOBLE_02688 2.1e-196 trkA P Oxidoreductase
HCIEOBLE_02689 1.3e-159 yrdQ K Transcriptional regulator
HCIEOBLE_02690 2.7e-169 yrdR EG EamA-like transporter family
HCIEOBLE_02691 3.9e-16 S YrzO-like protein
HCIEOBLE_02692 5.1e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HCIEOBLE_02693 6.5e-81 bltD 2.3.1.57 K FR47-like protein
HCIEOBLE_02694 1.8e-210 blt EGP Major facilitator Superfamily
HCIEOBLE_02695 6.5e-148 bltR K helix_turn_helix, mercury resistance
HCIEOBLE_02696 1.9e-106 yrkC G Cupin domain
HCIEOBLE_02697 5e-21
HCIEOBLE_02698 7.8e-39 yrkD S protein conserved in bacteria
HCIEOBLE_02699 7.3e-83 yrkE O DsrE/DsrF/DrsH-like family
HCIEOBLE_02700 1.4e-46 P Rhodanese Homology Domain
HCIEOBLE_02701 7.1e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
HCIEOBLE_02702 2.5e-206 yrkH P Rhodanese Homology Domain
HCIEOBLE_02703 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HCIEOBLE_02704 1.1e-112 yrkJ S membrane transporter protein
HCIEOBLE_02705 1.9e-111 K COG1802 Transcriptional regulators
HCIEOBLE_02706 2.7e-180 yjlA EG Putative multidrug resistance efflux transporter
HCIEOBLE_02708 1.8e-78 S Protein of unknown function with HXXEE motif
HCIEOBLE_02709 1.5e-97 ywrO S Flavodoxin-like fold
HCIEOBLE_02710 3.3e-21 cisA2 L Recombinase
HCIEOBLE_02711 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEOBLE_02712 3.1e-74 nucB M Deoxyribonuclease NucA/NucB
HCIEOBLE_02713 1.7e-131 yqeB
HCIEOBLE_02714 3.6e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HCIEOBLE_02715 1.8e-105 yqeD S SNARE associated Golgi protein
HCIEOBLE_02716 5.4e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCIEOBLE_02717 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HCIEOBLE_02719 5.3e-95 yqeG S hydrolase of the HAD superfamily
HCIEOBLE_02720 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HCIEOBLE_02721 1.7e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCIEOBLE_02722 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HCIEOBLE_02723 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCIEOBLE_02724 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HCIEOBLE_02725 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCIEOBLE_02726 2.7e-137 yqeM Q Methyltransferase
HCIEOBLE_02727 7.1e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCIEOBLE_02728 4.8e-95 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HCIEOBLE_02729 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HCIEOBLE_02730 0.0 comEC S Competence protein ComEC
HCIEOBLE_02731 4.1e-15 S YqzM-like protein
HCIEOBLE_02732 1.6e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
HCIEOBLE_02733 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HCIEOBLE_02734 1.9e-203 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HCIEOBLE_02735 7.6e-222 spoIIP M stage II sporulation protein P
HCIEOBLE_02736 7.2e-53 yqxA S Protein of unknown function (DUF3679)
HCIEOBLE_02737 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCIEOBLE_02738 1e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
HCIEOBLE_02739 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCIEOBLE_02740 8.5e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCIEOBLE_02741 0.0 dnaK O Heat shock 70 kDa protein
HCIEOBLE_02742 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCIEOBLE_02743 5.4e-175 prmA J Methylates ribosomal protein L11
HCIEOBLE_02744 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCIEOBLE_02745 4.6e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HCIEOBLE_02746 1.9e-156 yqeW P COG1283 Na phosphate symporter
HCIEOBLE_02747 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HCIEOBLE_02748 2.5e-61 yqeY S Yqey-like protein
HCIEOBLE_02749 6.5e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HCIEOBLE_02750 3.7e-121 yqfA S UPF0365 protein
HCIEOBLE_02751 5.1e-24 yqfB
HCIEOBLE_02752 2.7e-45 yqfC S sporulation protein YqfC
HCIEOBLE_02753 7.4e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HCIEOBLE_02754 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HCIEOBLE_02756 0.0 yqfF S membrane-associated HD superfamily hydrolase
HCIEOBLE_02757 3.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCIEOBLE_02758 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HCIEOBLE_02759 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HCIEOBLE_02760 5.8e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCIEOBLE_02761 8.4e-19 S YqzL-like protein
HCIEOBLE_02762 2e-143 recO L Involved in DNA repair and RecF pathway recombination
HCIEOBLE_02763 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HCIEOBLE_02764 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HCIEOBLE_02765 4.5e-112 ccpN K CBS domain
HCIEOBLE_02766 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCIEOBLE_02767 1.1e-86 yaiI S Belongs to the UPF0178 family
HCIEOBLE_02768 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCIEOBLE_02769 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCIEOBLE_02770 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HCIEOBLE_02771 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
HCIEOBLE_02772 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCIEOBLE_02773 1.3e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HCIEOBLE_02775 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCIEOBLE_02776 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCIEOBLE_02777 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HCIEOBLE_02778 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HCIEOBLE_02779 4.2e-77 zur P Belongs to the Fur family
HCIEOBLE_02780 1e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HCIEOBLE_02781 4.3e-62 yqfX S membrane
HCIEOBLE_02782 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HCIEOBLE_02783 5.2e-47 yqfZ M LysM domain
HCIEOBLE_02784 8.7e-131 yqgB S Protein of unknown function (DUF1189)
HCIEOBLE_02785 4e-73 yqgC S protein conserved in bacteria
HCIEOBLE_02786 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HCIEOBLE_02787 2.5e-231 yqgE EGP Major facilitator superfamily
HCIEOBLE_02788 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HCIEOBLE_02789 5.3e-151 pstS P Phosphate
HCIEOBLE_02790 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HCIEOBLE_02791 1.3e-157 pstA P Phosphate transport system permease
HCIEOBLE_02792 1.3e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCIEOBLE_02793 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCIEOBLE_02794 1.9e-75 yqzC S YceG-like family
HCIEOBLE_02795 9.2e-51 yqzD
HCIEOBLE_02797 2.3e-196 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HCIEOBLE_02798 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCIEOBLE_02799 1.7e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCIEOBLE_02800 2.5e-09 yqgO
HCIEOBLE_02801 2.5e-262 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HCIEOBLE_02802 3.1e-33 yqgQ S Protein conserved in bacteria
HCIEOBLE_02803 1.7e-179 glcK 2.7.1.2 G Glucokinase
HCIEOBLE_02804 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HCIEOBLE_02805 1.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HCIEOBLE_02806 3.7e-196 yqgU
HCIEOBLE_02807 6.9e-50 yqgV S Thiamine-binding protein
HCIEOBLE_02808 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HCIEOBLE_02809 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HCIEOBLE_02810 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HCIEOBLE_02811 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HCIEOBLE_02813 1.9e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HCIEOBLE_02814 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HCIEOBLE_02815 2.3e-173 corA P Mg2 transporter protein
HCIEOBLE_02818 5.9e-118 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HCIEOBLE_02819 1.4e-68 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HCIEOBLE_02820 2.1e-172 comGB NU COG1459 Type II secretory pathway, component PulF
HCIEOBLE_02821 1.7e-45 comGC U Required for transformation and DNA binding
HCIEOBLE_02822 2.4e-69 gspH NU protein transport across the cell outer membrane
HCIEOBLE_02823 9e-59 comGE
HCIEOBLE_02824 1.9e-33 comGF U Putative Competence protein ComGF
HCIEOBLE_02825 1.2e-43 S ComG operon protein 7
HCIEOBLE_02826 5.2e-26 yqzE S YqzE-like protein
HCIEOBLE_02827 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HCIEOBLE_02828 3e-115 yqxM
HCIEOBLE_02829 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HCIEOBLE_02830 1.9e-141 tasA S Cell division protein FtsN
HCIEOBLE_02831 1e-54 sinR K transcriptional
HCIEOBLE_02832 1.2e-24 sinI S Anti-repressor SinI
HCIEOBLE_02833 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HCIEOBLE_02834 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HCIEOBLE_02835 2.1e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HCIEOBLE_02836 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HCIEOBLE_02837 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HCIEOBLE_02838 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HCIEOBLE_02839 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HCIEOBLE_02840 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HCIEOBLE_02841 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
HCIEOBLE_02842 2.2e-61 yqhP
HCIEOBLE_02843 1.4e-173 yqhQ S Protein of unknown function (DUF1385)
HCIEOBLE_02844 6.6e-93 yqhR S Conserved membrane protein YqhR
HCIEOBLE_02845 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HCIEOBLE_02846 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HCIEOBLE_02847 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCIEOBLE_02848 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HCIEOBLE_02849 3e-170 spoIIIAA S stage III sporulation protein AA
HCIEOBLE_02850 3.2e-84 spoIIIAB S Stage III sporulation protein
HCIEOBLE_02851 7.6e-29 spoIIIAC S stage III sporulation protein AC
HCIEOBLE_02852 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HCIEOBLE_02853 1.4e-196 spoIIIAE S stage III sporulation protein AE
HCIEOBLE_02854 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HCIEOBLE_02855 2.2e-109 spoIIIAG S stage III sporulation protein AG
HCIEOBLE_02856 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HCIEOBLE_02857 2.6e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCIEOBLE_02858 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HCIEOBLE_02859 2.1e-67 yqhY S protein conserved in bacteria
HCIEOBLE_02860 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCIEOBLE_02861 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCIEOBLE_02862 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCIEOBLE_02863 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCIEOBLE_02864 5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCIEOBLE_02865 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCIEOBLE_02866 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HCIEOBLE_02867 1.7e-78 argR K Regulates arginine biosynthesis genes
HCIEOBLE_02868 9.3e-306 recN L May be involved in recombinational repair of damaged DNA
HCIEOBLE_02869 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HCIEOBLE_02870 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HCIEOBLE_02872 2.3e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HCIEOBLE_02873 6e-27
HCIEOBLE_02874 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HCIEOBLE_02875 7.9e-129 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCIEOBLE_02876 3.5e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
HCIEOBLE_02877 1.5e-155 hbdA 1.1.1.157 I Dehydrogenase
HCIEOBLE_02878 9.7e-211 mmgC I acyl-CoA dehydrogenase
HCIEOBLE_02879 2.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HCIEOBLE_02880 6.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HCIEOBLE_02881 2.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HCIEOBLE_02882 4e-34 yqzF S Protein of unknown function (DUF2627)
HCIEOBLE_02883 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HCIEOBLE_02884 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HCIEOBLE_02885 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCIEOBLE_02886 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HCIEOBLE_02887 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCIEOBLE_02888 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCIEOBLE_02889 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCIEOBLE_02890 2.6e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCIEOBLE_02891 3.4e-152 bmrR K helix_turn_helix, mercury resistance
HCIEOBLE_02892 7.9e-208 norA EGP Major facilitator Superfamily
HCIEOBLE_02893 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HCIEOBLE_02894 1.2e-76 yqiW S Belongs to the UPF0403 family
HCIEOBLE_02895 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
HCIEOBLE_02896 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HCIEOBLE_02897 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCIEOBLE_02898 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
HCIEOBLE_02899 3.4e-97 yqjB S protein conserved in bacteria
HCIEOBLE_02901 3e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HCIEOBLE_02902 1.6e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HCIEOBLE_02903 2.8e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HCIEOBLE_02904 2.7e-137 yqjF S Uncharacterized conserved protein (COG2071)
HCIEOBLE_02905 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCIEOBLE_02906 4.5e-24 yqzJ
HCIEOBLE_02907 1.8e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCIEOBLE_02908 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCIEOBLE_02909 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCIEOBLE_02910 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCIEOBLE_02911 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCIEOBLE_02912 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HCIEOBLE_02913 9e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HCIEOBLE_02914 0.0 rocB E arginine degradation protein
HCIEOBLE_02915 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCIEOBLE_02916 1.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HCIEOBLE_02917 6.6e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEOBLE_02918 3.2e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HCIEOBLE_02919 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HCIEOBLE_02920 2.1e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCIEOBLE_02922 1.3e-224 yqjV G Major Facilitator Superfamily
HCIEOBLE_02924 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCIEOBLE_02925 1.7e-49 S YolD-like protein
HCIEOBLE_02926 3.6e-87 yqjY K acetyltransferase
HCIEOBLE_02927 4.4e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HCIEOBLE_02928 3.5e-191 yqkA K GrpB protein
HCIEOBLE_02929 2.8e-54 yqkB S Belongs to the HesB IscA family
HCIEOBLE_02930 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HCIEOBLE_02931 1.1e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HCIEOBLE_02932 3.1e-12 yqkE S Protein of unknown function (DUF3886)
HCIEOBLE_02933 2.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HCIEOBLE_02935 5.8e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HCIEOBLE_02936 9e-220 yqxK 3.6.4.12 L DNA helicase
HCIEOBLE_02937 4.5e-58 ansR K Transcriptional regulator
HCIEOBLE_02938 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HCIEOBLE_02939 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HCIEOBLE_02940 1.1e-227 mleN C Na H antiporter
HCIEOBLE_02941 1.6e-241 mleA 1.1.1.38 C malic enzyme
HCIEOBLE_02942 3.2e-30 yqkK
HCIEOBLE_02943 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HCIEOBLE_02944 2.4e-80 fur P Belongs to the Fur family
HCIEOBLE_02945 3.7e-37 S Protein of unknown function (DUF4227)
HCIEOBLE_02946 2.2e-165 xerD L recombinase XerD
HCIEOBLE_02947 2.8e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HCIEOBLE_02948 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HCIEOBLE_02949 3.4e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HCIEOBLE_02950 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HCIEOBLE_02951 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HCIEOBLE_02952 9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEOBLE_02953 9.6e-112 spoVAA S Stage V sporulation protein AA
HCIEOBLE_02954 1e-67 spoVAB S Stage V sporulation protein AB
HCIEOBLE_02955 2.3e-78 spoVAC S stage V sporulation protein AC
HCIEOBLE_02956 9e-192 spoVAD I Stage V sporulation protein AD
HCIEOBLE_02957 2.2e-57 spoVAEB S stage V sporulation protein
HCIEOBLE_02958 1.4e-110 spoVAEA S stage V sporulation protein
HCIEOBLE_02959 3.1e-273 spoVAF EG Stage V sporulation protein AF
HCIEOBLE_02960 8.8e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCIEOBLE_02961 3.6e-149 ypuA S Secreted protein
HCIEOBLE_02962 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCIEOBLE_02964 6.2e-09 eaeH M Domain of Unknown Function (DUF1259)
HCIEOBLE_02966 2.5e-13 S PAP2 superfamily
HCIEOBLE_02968 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HCIEOBLE_02969 7.8e-55 ypuD
HCIEOBLE_02970 2.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCIEOBLE_02971 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
HCIEOBLE_02972 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HCIEOBLE_02973 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HCIEOBLE_02974 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCIEOBLE_02975 1.6e-91 ypuF S Domain of unknown function (DUF309)
HCIEOBLE_02976 1.3e-126 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCIEOBLE_02977 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCIEOBLE_02978 2.2e-96 ypuI S Protein of unknown function (DUF3907)
HCIEOBLE_02979 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HCIEOBLE_02980 3.5e-103 spmA S Spore maturation protein
HCIEOBLE_02981 1.9e-87 spmB S Spore maturation protein
HCIEOBLE_02982 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCIEOBLE_02983 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HCIEOBLE_02984 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HCIEOBLE_02985 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HCIEOBLE_02986 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_02987 0.0 resE 2.7.13.3 T Histidine kinase
HCIEOBLE_02988 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HCIEOBLE_02989 4.1e-198 rsiX
HCIEOBLE_02990 7.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HCIEOBLE_02991 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIEOBLE_02992 2.7e-84 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCIEOBLE_02993 4.7e-41 fer C Ferredoxin
HCIEOBLE_02994 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
HCIEOBLE_02995 1.7e-284 recQ 3.6.4.12 L DNA helicase
HCIEOBLE_02996 1.1e-99 ypbD S metal-dependent membrane protease
HCIEOBLE_02997 5.9e-76 ypbE M Lysin motif
HCIEOBLE_02998 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HCIEOBLE_02999 4.9e-145 ypbG S Calcineurin-like phosphoesterase superfamily domain
HCIEOBLE_03000 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HCIEOBLE_03001 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCIEOBLE_03002 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HCIEOBLE_03003 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
HCIEOBLE_03004 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HCIEOBLE_03005 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HCIEOBLE_03006 4.3e-110 ypfA M Flagellar protein YcgR
HCIEOBLE_03007 1.8e-23 S Family of unknown function (DUF5359)
HCIEOBLE_03008 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HCIEOBLE_03009 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HCIEOBLE_03010 7.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCIEOBLE_03011 1e-07 S YpzI-like protein
HCIEOBLE_03012 5.1e-102 yphA
HCIEOBLE_03013 2.5e-161 seaA S YIEGIA protein
HCIEOBLE_03014 6e-28 ypzH
HCIEOBLE_03015 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HCIEOBLE_03016 8.6e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HCIEOBLE_03017 1.2e-18 yphE S Protein of unknown function (DUF2768)
HCIEOBLE_03018 6e-137 yphF
HCIEOBLE_03019 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HCIEOBLE_03020 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCIEOBLE_03021 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HCIEOBLE_03022 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HCIEOBLE_03023 1.3e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HCIEOBLE_03024 7.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HCIEOBLE_03025 2.2e-193 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCIEOBLE_03026 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HCIEOBLE_03027 4.2e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HCIEOBLE_03028 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HCIEOBLE_03029 1.2e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HCIEOBLE_03030 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HCIEOBLE_03031 2.8e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCIEOBLE_03032 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCIEOBLE_03033 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HCIEOBLE_03034 2.7e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HCIEOBLE_03035 1.3e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCIEOBLE_03036 3.6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCIEOBLE_03037 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HCIEOBLE_03038 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HCIEOBLE_03039 3.2e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCIEOBLE_03040 5.9e-233 S COG0457 FOG TPR repeat
HCIEOBLE_03041 1.1e-98 ypiB S Belongs to the UPF0302 family
HCIEOBLE_03042 1.4e-75 ypiF S Protein of unknown function (DUF2487)
HCIEOBLE_03043 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HCIEOBLE_03044 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HCIEOBLE_03045 9.6e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HCIEOBLE_03046 5.2e-99 ypjA S membrane
HCIEOBLE_03047 1e-142 ypjB S sporulation protein
HCIEOBLE_03048 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HCIEOBLE_03049 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HCIEOBLE_03050 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCIEOBLE_03051 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HCIEOBLE_03052 1.7e-128 bshB1 S proteins, LmbE homologs
HCIEOBLE_03053 2.2e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HCIEOBLE_03054 1.3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCIEOBLE_03055 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCIEOBLE_03056 4.1e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HCIEOBLE_03057 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HCIEOBLE_03058 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HCIEOBLE_03059 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HCIEOBLE_03060 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HCIEOBLE_03061 2.2e-79 ypmB S protein conserved in bacteria
HCIEOBLE_03062 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HCIEOBLE_03063 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HCIEOBLE_03064 5.7e-129 dnaD L DNA replication protein DnaD
HCIEOBLE_03065 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCIEOBLE_03066 4e-92 ypoC
HCIEOBLE_03067 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HCIEOBLE_03068 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCIEOBLE_03069 2.8e-187 yppC S Protein of unknown function (DUF2515)
HCIEOBLE_03072 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
HCIEOBLE_03074 1e-47 yppG S YppG-like protein
HCIEOBLE_03075 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
HCIEOBLE_03076 3.3e-78 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HCIEOBLE_03077 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HCIEOBLE_03078 5.6e-236 yprB L RNase_H superfamily
HCIEOBLE_03079 2.8e-91 ypsA S Belongs to the UPF0398 family
HCIEOBLE_03080 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCIEOBLE_03081 3.5e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HCIEOBLE_03083 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HCIEOBLE_03084 1.5e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEOBLE_03085 8.2e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HCIEOBLE_03086 1.5e-186 ptxS K transcriptional
HCIEOBLE_03087 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HCIEOBLE_03088 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HCIEOBLE_03089 6.6e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HCIEOBLE_03090 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HCIEOBLE_03091 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCIEOBLE_03092 7.8e-228 pbuX F xanthine
HCIEOBLE_03093 1.1e-206 bcsA Q Naringenin-chalcone synthase
HCIEOBLE_03094 6.7e-87 ypbQ S protein conserved in bacteria
HCIEOBLE_03096 0.0 ypbR S Dynamin family
HCIEOBLE_03097 1e-38 ypbS S Protein of unknown function (DUF2533)
HCIEOBLE_03098 2e-07
HCIEOBLE_03099 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HCIEOBLE_03101 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
HCIEOBLE_03102 5.3e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HCIEOBLE_03103 3.2e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HCIEOBLE_03104 3e-29 ypeQ S Zinc-finger
HCIEOBLE_03105 8.1e-31 S Protein of unknown function (DUF2564)
HCIEOBLE_03106 3.8e-16 degR
HCIEOBLE_03107 7.9e-31 cspD K Cold-shock protein
HCIEOBLE_03108 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HCIEOBLE_03110 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HCIEOBLE_03111 3.2e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HCIEOBLE_03112 1.2e-106 ypgQ S phosphohydrolase
HCIEOBLE_03113 4.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
HCIEOBLE_03114 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HCIEOBLE_03115 1.7e-75 yphP S Belongs to the UPF0403 family
HCIEOBLE_03116 2.9e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HCIEOBLE_03117 2.5e-112 ypjP S YpjP-like protein
HCIEOBLE_03118 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HCIEOBLE_03119 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCIEOBLE_03120 3.7e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCIEOBLE_03121 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HCIEOBLE_03122 4.2e-110 hlyIII S protein, Hemolysin III
HCIEOBLE_03123 1.4e-184 pspF K Transcriptional regulator
HCIEOBLE_03124 1.6e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HCIEOBLE_03125 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HCIEOBLE_03126 1.2e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HCIEOBLE_03127 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HCIEOBLE_03128 1.1e-98 ypmS S protein conserved in bacteria
HCIEOBLE_03129 1.2e-28 ypmT S Uncharacterized ympT
HCIEOBLE_03130 1.7e-222 mepA V MATE efflux family protein
HCIEOBLE_03131 1.6e-70 ypoP K transcriptional
HCIEOBLE_03132 1.5e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCIEOBLE_03133 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HCIEOBLE_03134 7.4e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HCIEOBLE_03135 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HCIEOBLE_03136 6.3e-187 cgeB S Spore maturation protein
HCIEOBLE_03137 1.2e-65 cgeA
HCIEOBLE_03138 3.5e-38 cgeC
HCIEOBLE_03139 6.8e-253 cgeD M maturation of the outermost layer of the spore
HCIEOBLE_03140 1.8e-144 yiiD K acetyltransferase
HCIEOBLE_03142 2.2e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCIEOBLE_03143 9.3e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HCIEOBLE_03144 2.4e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HCIEOBLE_03145 3.5e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
HCIEOBLE_03146 1.1e-152 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HCIEOBLE_03147 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HCIEOBLE_03148 6.4e-47 yokU S YokU-like protein, putative antitoxin
HCIEOBLE_03149 1.4e-36 yozE S Belongs to the UPF0346 family
HCIEOBLE_03150 6e-123 yodN
HCIEOBLE_03152 2.8e-24 yozD S YozD-like protein
HCIEOBLE_03153 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
HCIEOBLE_03154 3.6e-54 yodL S YodL-like
HCIEOBLE_03155 5.3e-09
HCIEOBLE_03156 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HCIEOBLE_03157 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HCIEOBLE_03158 1.5e-23 yodI
HCIEOBLE_03159 6.3e-128 yodH Q Methyltransferase
HCIEOBLE_03160 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HCIEOBLE_03161 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCIEOBLE_03162 6.2e-28 S Protein of unknown function (DUF3311)
HCIEOBLE_03163 3.2e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
HCIEOBLE_03164 6.5e-113 mhqD S Carboxylesterase
HCIEOBLE_03165 1.4e-107 yodC C nitroreductase
HCIEOBLE_03166 4.4e-55 yodB K transcriptional
HCIEOBLE_03167 8e-64 yodA S tautomerase
HCIEOBLE_03168 4.6e-140 gntP EG COG2610 H gluconate symporter and related permeases
HCIEOBLE_03169 2e-36 gntP EG COG2610 H gluconate symporter and related permeases
HCIEOBLE_03170 2.6e-09
HCIEOBLE_03171 5.9e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
HCIEOBLE_03172 2.1e-160 rarD S -transporter
HCIEOBLE_03173 1.5e-43
HCIEOBLE_03174 2.2e-60 yojF S Protein of unknown function (DUF1806)
HCIEOBLE_03175 2.1e-125 yojG S deacetylase
HCIEOBLE_03176 4.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HCIEOBLE_03177 4.2e-245 norM V Multidrug efflux pump
HCIEOBLE_03179 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCIEOBLE_03180 3.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HCIEOBLE_03181 5.6e-196 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HCIEOBLE_03182 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HCIEOBLE_03183 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
HCIEOBLE_03184 0.0 yojO P Von Willebrand factor
HCIEOBLE_03185 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HCIEOBLE_03186 3.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HCIEOBLE_03187 1.1e-167 yocS S -transporter
HCIEOBLE_03188 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HCIEOBLE_03189 1.7e-164 sodA 1.15.1.1 P Superoxide dismutase
HCIEOBLE_03190 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HCIEOBLE_03191 6.8e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HCIEOBLE_03192 2.7e-31 yozC
HCIEOBLE_03193 4.2e-56 yozO S Bacterial PH domain
HCIEOBLE_03194 1.9e-36 yocN
HCIEOBLE_03195 1.1e-40 yozN
HCIEOBLE_03196 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HCIEOBLE_03197 6.2e-32
HCIEOBLE_03198 6.4e-54 yocL
HCIEOBLE_03199 3.3e-83 dksA T general stress protein
HCIEOBLE_03200 3e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCIEOBLE_03202 0.0 recQ 3.6.4.12 L DNA helicase
HCIEOBLE_03203 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HCIEOBLE_03204 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCIEOBLE_03205 7.1e-198 desK 2.7.13.3 T Histidine kinase
HCIEOBLE_03206 9.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HCIEOBLE_03207 6e-185 yocD 3.4.17.13 V peptidase S66
HCIEOBLE_03208 1.5e-91 yocC
HCIEOBLE_03209 5.1e-142
HCIEOBLE_03210 1.5e-92 yozB S membrane
HCIEOBLE_03211 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HCIEOBLE_03212 8.4e-51 czrA K transcriptional
HCIEOBLE_03213 8.8e-93 yobW
HCIEOBLE_03214 4.6e-174 yobV K WYL domain
HCIEOBLE_03215 1.7e-84 yobU K Bacterial transcription activator, effector binding domain
HCIEOBLE_03216 1e-130 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HCIEOBLE_03217 1.3e-97 yobS K Transcriptional regulator
HCIEOBLE_03218 5.2e-129 yobR 2.3.1.1 J FR47-like protein
HCIEOBLE_03219 1.8e-130 yobQ K helix_turn_helix, arabinose operon control protein
HCIEOBLE_03220 4.2e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HCIEOBLE_03221 8.6e-273 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HCIEOBLE_03222 4.8e-102 yokH G SMI1 / KNR4 family
HCIEOBLE_03223 4.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HCIEOBLE_03224 6.9e-19
HCIEOBLE_03226 1.8e-95 S aspartate phosphatase
HCIEOBLE_03227 1.3e-63 yoaQ S Evidence 4 Homologs of previously reported genes of
HCIEOBLE_03229 1.6e-115
HCIEOBLE_03231 2.8e-77 mepB S MepB protein
HCIEOBLE_03233 7e-56 K Helix-turn-helix
HCIEOBLE_03234 2e-36 S TM2 domain
HCIEOBLE_03235 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HCIEOBLE_03236 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HCIEOBLE_03240 5.9e-166 bla 3.5.2.6 V beta-lactamase
HCIEOBLE_03241 1.4e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HCIEOBLE_03242 1.6e-76 yoaW
HCIEOBLE_03243 4e-156 yijE EG EamA-like transporter family
HCIEOBLE_03244 2.5e-158 yoaU K LysR substrate binding domain
HCIEOBLE_03245 8.2e-148 yoaT S Protein of unknown function (DUF817)
HCIEOBLE_03246 4.4e-30 yozG K Transcriptional regulator
HCIEOBLE_03247 1.8e-73 yoaS S Protein of unknown function (DUF2975)
HCIEOBLE_03248 2.1e-171 yoaR V vancomycin resistance protein
HCIEOBLE_03249 8.9e-84
HCIEOBLE_03252 6.7e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
HCIEOBLE_03255 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
HCIEOBLE_03256 3.6e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HCIEOBLE_03257 1.5e-110 yoaK S Membrane
HCIEOBLE_03258 1.5e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HCIEOBLE_03259 2e-277 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HCIEOBLE_03260 2e-180 mcpU NT methyl-accepting chemotaxis protein
HCIEOBLE_03261 8.2e-37 S Protein of unknown function (DUF4025)
HCIEOBLE_03262 2.6e-13
HCIEOBLE_03263 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
HCIEOBLE_03264 3.2e-33 yoaF
HCIEOBLE_03265 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCIEOBLE_03266 1.1e-181 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIEOBLE_03267 5.9e-277 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HCIEOBLE_03268 3.4e-233 yoaB EGP Major facilitator Superfamily
HCIEOBLE_03269 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
HCIEOBLE_03270 1.1e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
HCIEOBLE_03271 2.3e-91 V ABC-2 family transporter protein
HCIEOBLE_03272 1.3e-126 V ABC-2 family transporter protein
HCIEOBLE_03273 2.7e-94 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HCIEOBLE_03274 2.9e-134 yoxB
HCIEOBLE_03275 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
HCIEOBLE_03276 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIEOBLE_03277 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HCIEOBLE_03278 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCIEOBLE_03279 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCIEOBLE_03280 7.8e-155 gltC K Transcriptional regulator
HCIEOBLE_03281 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HCIEOBLE_03282 6.6e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HCIEOBLE_03283 6.7e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HCIEOBLE_03284 1.1e-153 gltR1 K Transcriptional regulator
HCIEOBLE_03285 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HCIEOBLE_03286 3e-34 yoeD G Helix-turn-helix domain
HCIEOBLE_03287 2.2e-96 L Integrase
HCIEOBLE_03289 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HCIEOBLE_03290 2.3e-246 yoeA V MATE efflux family protein
HCIEOBLE_03291 2.7e-185 yoxA 5.1.3.3 G Aldose 1-epimerase
HCIEOBLE_03292 1.3e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HCIEOBLE_03293 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIEOBLE_03294 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIEOBLE_03296 4.6e-157 ydhU P Catalase
HCIEOBLE_03297 3.2e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HCIEOBLE_03298 3.1e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
HCIEOBLE_03299 9.5e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HCIEOBLE_03300 4.3e-132 ydhQ K UTRA
HCIEOBLE_03301 2.5e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIEOBLE_03302 1.7e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIEOBLE_03303 9.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HCIEOBLE_03304 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HCIEOBLE_03305 4.6e-200 pbuE EGP Major facilitator Superfamily
HCIEOBLE_03306 2.5e-98 ydhK M Protein of unknown function (DUF1541)
HCIEOBLE_03307 2.8e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCIEOBLE_03308 3.4e-80 K Acetyltransferase (GNAT) domain
HCIEOBLE_03310 4.3e-67 frataxin S Domain of unknown function (DU1801)
HCIEOBLE_03311 3.8e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HCIEOBLE_03312 4.3e-124
HCIEOBLE_03313 4.5e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HCIEOBLE_03314 1.4e-239 ydhD M Glycosyl hydrolase
HCIEOBLE_03315 3.2e-121 ydhC K FCD
HCIEOBLE_03316 7.9e-121 ydhB S membrane transporter protein
HCIEOBLE_03317 2.8e-208 tcaB EGP Major facilitator Superfamily
HCIEOBLE_03318 2.4e-69 ydgJ K Winged helix DNA-binding domain
HCIEOBLE_03319 1e-113 drgA C nitroreductase
HCIEOBLE_03320 0.0 ydgH S drug exporters of the RND superfamily
HCIEOBLE_03321 2.7e-79 K helix_turn_helix multiple antibiotic resistance protein
HCIEOBLE_03322 8.1e-88 dinB S DinB family
HCIEOBLE_03323 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HCIEOBLE_03324 3.7e-304 expZ S ABC transporter
HCIEOBLE_03325 6.9e-102 G Xylose isomerase-like TIM barrel
HCIEOBLE_03326 2e-191 csbC EGP Major facilitator Superfamily
HCIEOBLE_03327 3.5e-119 purR K helix_turn _helix lactose operon repressor
HCIEOBLE_03328 3.3e-133 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HCIEOBLE_03329 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
HCIEOBLE_03330 1.4e-51 S DoxX-like family
HCIEOBLE_03331 5.3e-99 K Bacterial regulatory proteins, tetR family
HCIEOBLE_03332 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HCIEOBLE_03333 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
HCIEOBLE_03334 3.2e-74 cotP O Belongs to the small heat shock protein (HSP20) family
HCIEOBLE_03335 2.6e-121 ydfS S Protein of unknown function (DUF421)
HCIEOBLE_03336 1.9e-99 ydfR S Protein of unknown function (DUF421)
HCIEOBLE_03338 6.3e-29
HCIEOBLE_03339 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HCIEOBLE_03340 1.7e-54 traF CO Thioredoxin
HCIEOBLE_03341 8.8e-63 mhqP S DoxX
HCIEOBLE_03342 6.8e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HCIEOBLE_03343 9.6e-112 ydfN C nitroreductase
HCIEOBLE_03344 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCIEOBLE_03345 6.6e-145 K Bacterial transcription activator, effector binding domain
HCIEOBLE_03346 8.5e-117 S Protein of unknown function (DUF554)
HCIEOBLE_03347 7.5e-174 S Alpha/beta hydrolase family
HCIEOBLE_03348 0.0 ydfJ S drug exporters of the RND superfamily
HCIEOBLE_03349 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCIEOBLE_03350 8.5e-178 ydfH 2.7.13.3 T Histidine kinase
HCIEOBLE_03352 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HCIEOBLE_03353 6.6e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HCIEOBLE_03354 4.2e-115 ydfE S Flavin reductase like domain
HCIEOBLE_03355 1.9e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCIEOBLE_03356 4.2e-132 ydfC EG EamA-like transporter family
HCIEOBLE_03357 3.4e-122 T Transcriptional regulatory protein, C terminal
HCIEOBLE_03358 6.6e-212 T GHKL domain
HCIEOBLE_03359 1.5e-158
HCIEOBLE_03360 3.3e-11 nodB1 G deacetylase
HCIEOBLE_03361 3.1e-90 nodB1 G deacetylase
HCIEOBLE_03362 2.8e-149 lytR K Transcriptional regulator
HCIEOBLE_03363 4.6e-143 ydfB J GNAT acetyltransferase
HCIEOBLE_03364 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HCIEOBLE_03365 6.3e-57 arsR K transcriptional
HCIEOBLE_03366 3.2e-104 ydeS K Transcriptional regulator
HCIEOBLE_03367 2e-190 ydeR EGP Major facilitator Superfamily
HCIEOBLE_03368 4.3e-109 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HCIEOBLE_03369 4.8e-69 ydeP K Transcriptional regulator
HCIEOBLE_03370 3.5e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HCIEOBLE_03371 4e-56 K HxlR-like helix-turn-helix
HCIEOBLE_03372 1.3e-102 ydeN S Serine hydrolase
HCIEOBLE_03373 1.6e-73 maoC I N-terminal half of MaoC dehydratase
HCIEOBLE_03374 3.3e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCIEOBLE_03375 1.2e-152 ydeK EG -transporter
HCIEOBLE_03376 5.8e-65 lrpA K transcriptional
HCIEOBLE_03377 3.5e-132 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HCIEOBLE_03378 3.4e-258 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCIEOBLE_03379 6.8e-159 K Transcriptional regulator
HCIEOBLE_03380 4.5e-72 S SNARE associated Golgi protein
HCIEOBLE_03381 1e-140 T PhoQ Sensor
HCIEOBLE_03382 8.7e-114 T Transcriptional regulator
HCIEOBLE_03383 2.1e-71 ksgA1 I Ribosomal RNA adenine dimethylase
HCIEOBLE_03384 2.9e-82
HCIEOBLE_03385 1.7e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HCIEOBLE_03386 1.9e-51 ydeH
HCIEOBLE_03387 1.3e-216 ydeG EGP Major facilitator superfamily
HCIEOBLE_03388 2.8e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCIEOBLE_03389 1.5e-163 ydeE K AraC family transcriptional regulator
HCIEOBLE_03390 2.6e-161 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HCIEOBLE_03391 6.4e-162 rhaS5 K AraC-like ligand binding domain
HCIEOBLE_03392 1.8e-143 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HCIEOBLE_03393 9.8e-77 carD K Transcription factor
HCIEOBLE_03394 8.7e-30 cspL K Cold shock
HCIEOBLE_03395 8.3e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HCIEOBLE_03396 6.7e-72 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HCIEOBLE_03397 4e-179 arsB 1.20.4.1 P Arsenic resistance protein
HCIEOBLE_03398 9e-72 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCIEOBLE_03399 7.5e-52 arsR K ArsR family transcriptional regulator
HCIEOBLE_03400 2.3e-66 S DinB superfamily
HCIEOBLE_03409 6.8e-83 ydcK S Belongs to the SprT family
HCIEOBLE_03410 0.0 yhgF K COG2183 Transcriptional accessory protein
HCIEOBLE_03411 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HCIEOBLE_03412 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCIEOBLE_03413 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HCIEOBLE_03414 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HCIEOBLE_03415 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HCIEOBLE_03416 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HCIEOBLE_03417 5.2e-57 rsbS T antagonist
HCIEOBLE_03418 1.3e-143 rsbR T Positive regulator of sigma-B
HCIEOBLE_03419 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HCIEOBLE_03420 1.4e-41 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HCIEOBLE_03421 2.1e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCIEOBLE_03422 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HCIEOBLE_03423 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCIEOBLE_03424 9e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HCIEOBLE_03425 4.3e-259 ydbT S Membrane
HCIEOBLE_03426 2.1e-82 ydbS S Bacterial PH domain
HCIEOBLE_03427 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCIEOBLE_03428 2.7e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCIEOBLE_03429 4.8e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HCIEOBLE_03430 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HCIEOBLE_03431 1.3e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCIEOBLE_03432 2.2e-07 S Fur-regulated basic protein A
HCIEOBLE_03433 1.1e-18 S Fur-regulated basic protein B
HCIEOBLE_03434 3.7e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HCIEOBLE_03435 2.7e-52 ydbL
HCIEOBLE_03436 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HCIEOBLE_03437 8e-171 ydbJ V ABC transporter, ATP-binding protein
HCIEOBLE_03438 4.4e-181 ydbI S AI-2E family transporter
HCIEOBLE_03439 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCIEOBLE_03440 8.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HCIEOBLE_03441 6.2e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HCIEOBLE_03442 6.7e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HCIEOBLE_03443 7.9e-154 ydbD P Catalase
HCIEOBLE_03444 3.1e-56 ydbB G Cupin domain
HCIEOBLE_03446 5.5e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HCIEOBLE_03447 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HCIEOBLE_03449 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HCIEOBLE_03450 9.4e-40
HCIEOBLE_03451 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCIEOBLE_03452 5.3e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HCIEOBLE_03453 0.0 ydaO E amino acid
HCIEOBLE_03454 0.0 ydaN S Bacterial cellulose synthase subunit
HCIEOBLE_03455 4.5e-233 ydaM M Glycosyl transferase family group 2
HCIEOBLE_03456 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HCIEOBLE_03457 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
HCIEOBLE_03458 2.1e-207 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HCIEOBLE_03459 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCIEOBLE_03460 7.3e-74 lrpC K Transcriptional regulator
HCIEOBLE_03461 3.6e-45 ydzA EGP Major facilitator Superfamily
HCIEOBLE_03462 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HCIEOBLE_03463 6.8e-77 ydaG 1.4.3.5 S general stress protein
HCIEOBLE_03464 2.3e-101 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HCIEOBLE_03465 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HCIEOBLE_03466 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEOBLE_03467 2.7e-95 ydaC Q Methyltransferase domain
HCIEOBLE_03468 5.5e-294 ydaB IQ acyl-CoA ligase
HCIEOBLE_03469 0.0 mtlR K transcriptional regulator, MtlR
HCIEOBLE_03470 1.8e-175 ydhF S Oxidoreductase
HCIEOBLE_03471 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HCIEOBLE_03472 5.3e-46 yczJ S biosynthesis
HCIEOBLE_03474 7.1e-118 ycsK E anatomical structure formation involved in morphogenesis
HCIEOBLE_03475 2.7e-132 kipR K Transcriptional regulator
HCIEOBLE_03476 6.6e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HCIEOBLE_03477 1e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HCIEOBLE_03478 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
HCIEOBLE_03479 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HCIEOBLE_03480 2.3e-139 ycsF S Belongs to the UPF0271 (lamB) family
HCIEOBLE_03481 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HCIEOBLE_03483 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HCIEOBLE_03484 1.2e-103 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HCIEOBLE_03485 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HCIEOBLE_03487 4.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HCIEOBLE_03488 1.4e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HCIEOBLE_03489 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HCIEOBLE_03490 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HCIEOBLE_03491 3.4e-53
HCIEOBLE_03492 4.7e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HCIEOBLE_03493 1.2e-307 ycnJ P protein, homolog of Cu resistance protein CopC
HCIEOBLE_03494 1.4e-99 ycnI S protein conserved in bacteria
HCIEOBLE_03495 6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEOBLE_03496 6.1e-149 glcU U Glucose uptake
HCIEOBLE_03497 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCIEOBLE_03498 1.3e-243 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCIEOBLE_03499 4.3e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCIEOBLE_03500 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HCIEOBLE_03501 1.6e-45 ycnE S Monooxygenase
HCIEOBLE_03502 5.7e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HCIEOBLE_03503 6.5e-154 ycnC K Transcriptional regulator
HCIEOBLE_03504 1.2e-250 ycnB EGP Major facilitator Superfamily
HCIEOBLE_03505 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HCIEOBLE_03506 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HCIEOBLE_03507 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_03508 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_03509 1.2e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
HCIEOBLE_03513 3.1e-71 S aspartate phosphatase
HCIEOBLE_03514 1.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HCIEOBLE_03515 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_03516 4.9e-199 yclI V ABC transporter (permease) YclI
HCIEOBLE_03517 1.6e-120 yclH P ABC transporter
HCIEOBLE_03518 1.1e-193 gerKB F Spore germination protein
HCIEOBLE_03519 2.8e-224 gerKC S spore germination
HCIEOBLE_03520 6.4e-280 gerKA EG Spore germination protein
HCIEOBLE_03522 1.8e-309 yclG M Pectate lyase superfamily protein
HCIEOBLE_03523 1.5e-267 dtpT E amino acid peptide transporter
HCIEOBLE_03524 7.8e-157 yclE 3.4.11.5 S Alpha beta hydrolase
HCIEOBLE_03525 2.5e-80 yclD
HCIEOBLE_03526 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
HCIEOBLE_03527 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HCIEOBLE_03528 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HCIEOBLE_03529 1.9e-161 bsdA K LysR substrate binding domain
HCIEOBLE_03530 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HCIEOBLE_03531 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HCIEOBLE_03532 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCIEOBLE_03533 9.7e-115 yczE S membrane
HCIEOBLE_03534 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HCIEOBLE_03535 3.4e-247 ycxD K GntR family transcriptional regulator
HCIEOBLE_03536 5.8e-161 ycxC EG EamA-like transporter family
HCIEOBLE_03537 1.3e-88 S YcxB-like protein
HCIEOBLE_03538 1.8e-223 EGP Major Facilitator Superfamily
HCIEOBLE_03539 7.5e-140 srfAD Q thioesterase
HCIEOBLE_03540 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HCIEOBLE_03541 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIEOBLE_03542 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIEOBLE_03543 1.3e-63 hxlR K transcriptional
HCIEOBLE_03544 1.8e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HCIEOBLE_03545 1.1e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HCIEOBLE_03546 1.2e-183 tlpC 2.7.13.3 NT chemotaxis protein
HCIEOBLE_03547 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
HCIEOBLE_03548 1.1e-68 nin S Competence protein J (ComJ)
HCIEOBLE_03549 5.7e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIEOBLE_03550 3.5e-52 yckD S Protein of unknown function (DUF2680)
HCIEOBLE_03551 9.6e-77 yckC S membrane
HCIEOBLE_03553 1.7e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HCIEOBLE_03554 1.2e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
HCIEOBLE_03555 5e-226 yciC S GTPases (G3E family)
HCIEOBLE_03556 2e-106 yciB M ErfK YbiS YcfS YnhG
HCIEOBLE_03557 1.3e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HCIEOBLE_03558 1.3e-221 nasA P COG2223 Nitrate nitrite transporter
HCIEOBLE_03559 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HCIEOBLE_03560 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCIEOBLE_03561 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HCIEOBLE_03562 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HCIEOBLE_03563 5.6e-272 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HCIEOBLE_03564 3e-187 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HCIEOBLE_03565 8.5e-159 I alpha/beta hydrolase fold
HCIEOBLE_03566 1.3e-138 ycgR S permeases
HCIEOBLE_03567 8.3e-146 ycgQ S membrane
HCIEOBLE_03568 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HCIEOBLE_03569 5.9e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCIEOBLE_03570 1.6e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HCIEOBLE_03571 5.1e-170 ycgM E Proline dehydrogenase
HCIEOBLE_03572 2.4e-144 ycgL S Predicted nucleotidyltransferase
HCIEOBLE_03573 2.5e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HCIEOBLE_03574 2.7e-177 oxyR3 K LysR substrate binding domain
HCIEOBLE_03575 1.8e-144 yafE Q ubiE/COQ5 methyltransferase family
HCIEOBLE_03576 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HCIEOBLE_03577 9.9e-106 tmrB S AAA domain
HCIEOBLE_03578 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCIEOBLE_03579 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HCIEOBLE_03580 1.4e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HCIEOBLE_03581 4.4e-151 yqcI S YqcI/YcgG family
HCIEOBLE_03582 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HCIEOBLE_03583 7.5e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HCIEOBLE_03584 2.8e-261 mdr EGP Major facilitator Superfamily
HCIEOBLE_03585 6.5e-293 lctP C L-lactate permease
HCIEOBLE_03586 2.8e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HCIEOBLE_03587 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HCIEOBLE_03588 4.1e-81 ycgB
HCIEOBLE_03589 1.8e-254 ycgA S Membrane
HCIEOBLE_03590 5e-215 amhX S amidohydrolase
HCIEOBLE_03591 5.3e-164 opuAC E glycine betaine
HCIEOBLE_03592 1.3e-127 opuAB P glycine betaine
HCIEOBLE_03593 4.3e-228 proV 3.6.3.32 E glycine betaine
HCIEOBLE_03594 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCIEOBLE_03595 3.3e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
HCIEOBLE_03596 2.5e-217 naiP P Uncharacterised MFS-type transporter YbfB
HCIEOBLE_03597 1.3e-191 yceH P Belongs to the TelA family
HCIEOBLE_03598 0.0 yceG S Putative component of 'biosynthetic module'
HCIEOBLE_03599 6.3e-137 terC P Protein of unknown function (DUF475)
HCIEOBLE_03600 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HCIEOBLE_03601 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HCIEOBLE_03602 1.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HCIEOBLE_03603 8e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCIEOBLE_03604 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HCIEOBLE_03605 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HCIEOBLE_03606 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
HCIEOBLE_03607 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HCIEOBLE_03608 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HCIEOBLE_03609 2.1e-173 S response regulator aspartate phosphatase
HCIEOBLE_03610 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
HCIEOBLE_03611 2.9e-255 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HCIEOBLE_03612 7.2e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HCIEOBLE_03613 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HCIEOBLE_03614 3.9e-173 yccK C Aldo keto reductase
HCIEOBLE_03615 6.7e-199 natB CP ABC-2 family transporter protein
HCIEOBLE_03616 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HCIEOBLE_03617 1.2e-126 lytR_2 T LytTr DNA-binding domain
HCIEOBLE_03618 4.3e-159 2.7.13.3 T GHKL domain
HCIEOBLE_03619 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
HCIEOBLE_03620 2e-59 S RDD family
HCIEOBLE_03621 9.3e-102 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HCIEOBLE_03622 1.4e-150 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HCIEOBLE_03623 1.7e-22 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HCIEOBLE_03624 4.8e-102 yxaF K Transcriptional regulator
HCIEOBLE_03625 5.8e-229 lmrB EGP the major facilitator superfamily
HCIEOBLE_03626 9.5e-203 ycbU E Selenocysteine lyase
HCIEOBLE_03627 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HCIEOBLE_03628 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HCIEOBLE_03629 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HCIEOBLE_03630 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HCIEOBLE_03631 6.2e-134 ycbR T vWA found in TerF C terminus
HCIEOBLE_03632 8.2e-78 sleB 3.5.1.28 M Cell wall
HCIEOBLE_03633 4.1e-52 ycbP S Protein of unknown function (DUF2512)
HCIEOBLE_03634 2.1e-112 S ABC-2 family transporter protein
HCIEOBLE_03635 5.9e-166 ycbN V ABC transporter, ATP-binding protein
HCIEOBLE_03636 4.9e-168 T PhoQ Sensor
HCIEOBLE_03637 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCIEOBLE_03638 9.9e-169 eamA1 EG spore germination
HCIEOBLE_03639 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HCIEOBLE_03640 5.3e-175 ycbJ S Macrolide 2'-phosphotransferase
HCIEOBLE_03641 4.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
HCIEOBLE_03642 2.1e-123 ycbG K FCD
HCIEOBLE_03643 9.4e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HCIEOBLE_03644 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HCIEOBLE_03645 3.8e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCIEOBLE_03646 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HCIEOBLE_03647 2.6e-169 glnL T Regulator
HCIEOBLE_03648 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
HCIEOBLE_03649 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
HCIEOBLE_03650 9.6e-256 agcS E Sodium alanine symporter
HCIEOBLE_03651 4.8e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HCIEOBLE_03652 1.3e-260 mmuP E amino acid
HCIEOBLE_03653 1.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HCIEOBLE_03655 3.1e-128 K UTRA
HCIEOBLE_03656 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCIEOBLE_03657 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCIEOBLE_03658 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCIEOBLE_03659 3.9e-192 yceA S Belongs to the UPF0176 family
HCIEOBLE_03660 2e-166 ybfP K Transcriptional regulator
HCIEOBLE_03661 3.5e-252 S Erythromycin esterase
HCIEOBLE_03662 1.7e-44 ybfN
HCIEOBLE_03663 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HCIEOBLE_03664 2.7e-85 ybfM S SNARE associated Golgi protein
HCIEOBLE_03665 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCIEOBLE_03666 2e-163 S Alpha/beta hydrolase family
HCIEOBLE_03668 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HCIEOBLE_03669 4.7e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HCIEOBLE_03670 9.7e-144 msmR K AraC-like ligand binding domain
HCIEOBLE_03671 3.1e-159 ybfH EG EamA-like transporter family
HCIEOBLE_03672 8.2e-219 ybfB G COG0477 Permeases of the major facilitator superfamily
HCIEOBLE_03673 2.2e-168 ybfA 3.4.15.5 K FR47-like protein
HCIEOBLE_03674 1.5e-34 S Protein of unknown function (DUF2651)
HCIEOBLE_03675 7.3e-258 glpT G -transporter
HCIEOBLE_03676 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCIEOBLE_03677 8.9e-290 ybeC E amino acid
HCIEOBLE_03678 4.9e-41 ybyB
HCIEOBLE_03679 4.3e-244 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HCIEOBLE_03680 2.2e-148 ybxI 3.5.2.6 V beta-lactamase
HCIEOBLE_03681 4.9e-30 ybxH S Family of unknown function (DUF5370)
HCIEOBLE_03682 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
HCIEOBLE_03683 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HCIEOBLE_03684 4.9e-213 ybdO S Domain of unknown function (DUF4885)
HCIEOBLE_03685 1.2e-152 ybdN
HCIEOBLE_03686 7.9e-140 KLT Protein tyrosine kinase
HCIEOBLE_03688 3.2e-170 T His Kinase A (phospho-acceptor) domain
HCIEOBLE_03689 2.9e-122 T Transcriptional regulatory protein, C terminal
HCIEOBLE_03690 7.6e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HCIEOBLE_03691 1e-16
HCIEOBLE_03692 2.5e-56
HCIEOBLE_03693 2.1e-200 ybcL EGP Major facilitator Superfamily
HCIEOBLE_03694 5.1e-50 ybzH K Helix-turn-helix domain
HCIEOBLE_03695 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HCIEOBLE_03696 8.7e-47
HCIEOBLE_03698 1.1e-89 can 4.2.1.1 P carbonic anhydrase
HCIEOBLE_03699 0.0 ybcC S Belongs to the UPF0753 family
HCIEOBLE_03700 2.2e-271 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HCIEOBLE_03701 1.2e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCIEOBLE_03702 4.9e-119 adaA 3.2.2.21 K Transcriptional regulator
HCIEOBLE_03703 4.5e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HCIEOBLE_03704 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCIEOBLE_03705 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCIEOBLE_03706 3e-225 ybbR S protein conserved in bacteria
HCIEOBLE_03707 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCIEOBLE_03708 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HCIEOBLE_03709 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HCIEOBLE_03715 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HCIEOBLE_03716 1.9e-86 ybbJ J acetyltransferase
HCIEOBLE_03717 3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCIEOBLE_03718 1.4e-150 ybbH K transcriptional
HCIEOBLE_03719 3.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCIEOBLE_03720 5.4e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HCIEOBLE_03721 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HCIEOBLE_03722 3.5e-238 ybbC 3.2.1.52 S protein conserved in bacteria
HCIEOBLE_03723 5e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HCIEOBLE_03724 4e-165 feuA P Iron-uptake system-binding protein
HCIEOBLE_03725 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_03726 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_03727 1.4e-141 ybbA S Putative esterase
HCIEOBLE_03728 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
HCIEOBLE_03730 1e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HCIEOBLE_03732 2.5e-166 ygxA S Nucleotidyltransferase-like
HCIEOBLE_03733 9.5e-56 ygzB S UPF0295 protein
HCIEOBLE_03734 4e-80 perR P Belongs to the Fur family
HCIEOBLE_03735 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
HCIEOBLE_03736 7.6e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HCIEOBLE_03737 3.3e-179 ygaE S Membrane
HCIEOBLE_03738 1.8e-301 ygaD V ABC transporter
HCIEOBLE_03739 1.3e-104 ygaC J Belongs to the UPF0374 family
HCIEOBLE_03740 4.9e-48 ygaB S YgaB-like protein
HCIEOBLE_03741 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HCIEOBLE_03742 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCIEOBLE_03743 6.9e-36 yfhS
HCIEOBLE_03744 3.3e-210 mutY L A G-specific
HCIEOBLE_03745 2.1e-185 yfhP S membrane-bound metal-dependent
HCIEOBLE_03746 0.0 yfhO S Bacterial membrane protein YfhO
HCIEOBLE_03747 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCIEOBLE_03748 1.3e-170 yfhM S Alpha beta hydrolase
HCIEOBLE_03749 3.9e-50 yfhL S SdpI/YhfL protein family
HCIEOBLE_03750 2.3e-90 batE T Bacterial SH3 domain homologues
HCIEOBLE_03751 1.3e-44 yfhJ S WVELL protein
HCIEOBLE_03752 6.2e-20 sspK S reproduction
HCIEOBLE_03753 1.5e-209 yfhI EGP Major facilitator Superfamily
HCIEOBLE_03754 1.7e-51 yfhH S Protein of unknown function (DUF1811)
HCIEOBLE_03755 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HCIEOBLE_03756 9.3e-172 yfhF S nucleoside-diphosphate sugar epimerase
HCIEOBLE_03758 2.1e-25 yfhD S YfhD-like protein
HCIEOBLE_03759 3.9e-107 yfhC C nitroreductase
HCIEOBLE_03760 6.2e-165 yfhB 5.3.3.17 S PhzF family
HCIEOBLE_03761 1.5e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_03762 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_03763 5.7e-175 yfiY P ABC transporter substrate-binding protein
HCIEOBLE_03764 1.6e-199 L COG3666 Transposase and inactivated derivatives
HCIEOBLE_03765 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCIEOBLE_03766 1.4e-78 yfiV K transcriptional
HCIEOBLE_03767 6.9e-284 yfiU EGP Major facilitator Superfamily
HCIEOBLE_03768 4.7e-99 yfiT S Belongs to the metal hydrolase YfiT family
HCIEOBLE_03769 3.8e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HCIEOBLE_03770 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HCIEOBLE_03771 8.3e-99 padR K transcriptional
HCIEOBLE_03772 2.9e-202 V COG0842 ABC-type multidrug transport system, permease component
HCIEOBLE_03773 3.4e-206 V ABC-2 family transporter protein
HCIEOBLE_03774 9.2e-167 V ABC transporter, ATP-binding protein
HCIEOBLE_03775 1.6e-112 KT LuxR family transcriptional regulator
HCIEOBLE_03776 1.7e-210 yxjM T Histidine kinase
HCIEOBLE_03778 5.7e-163 yfiE 1.13.11.2 S glyoxalase
HCIEOBLE_03779 6.4e-64 mhqP S DoxX
HCIEOBLE_03780 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCIEOBLE_03781 1.3e-307 yfiB3 V ABC transporter
HCIEOBLE_03782 0.0 yobO M COG5434 Endopolygalacturonase
HCIEOBLE_03783 2.6e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCIEOBLE_03784 4.6e-140 glvR K Helix-turn-helix domain, rpiR family
HCIEOBLE_03785 1.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HCIEOBLE_03786 2.6e-44 yfjA S Belongs to the WXG100 family
HCIEOBLE_03787 1e-189 yfjB
HCIEOBLE_03788 4.5e-143 yfjC
HCIEOBLE_03789 5.1e-96 yfjD S Family of unknown function (DUF5381)
HCIEOBLE_03790 4e-56 yfjF S UPF0060 membrane protein
HCIEOBLE_03791 1.3e-24 sspH S Belongs to the SspH family
HCIEOBLE_03792 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HCIEOBLE_03793 4.3e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCIEOBLE_03794 1.9e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCIEOBLE_03795 2.1e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCIEOBLE_03796 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCIEOBLE_03797 9.6e-85 yfjM S Psort location Cytoplasmic, score
HCIEOBLE_03798 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCIEOBLE_03799 2.3e-44 S YfzA-like protein
HCIEOBLE_03800 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCIEOBLE_03801 1.7e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HCIEOBLE_03802 1.7e-184 corA P Mediates influx of magnesium ions
HCIEOBLE_03803 2e-144 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HCIEOBLE_03804 1.7e-153 pdaA G deacetylase
HCIEOBLE_03805 1.1e-26 yfjT
HCIEOBLE_03806 2.1e-221 yfkA S YfkB-like domain
HCIEOBLE_03807 6e-149 yfkC M Mechanosensitive ion channel
HCIEOBLE_03808 1.2e-146 yfkD S YfkD-like protein
HCIEOBLE_03809 3e-182 cax P COG0387 Ca2 H antiporter
HCIEOBLE_03810 1e-215 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HCIEOBLE_03812 9.7e-144 yihY S Belongs to the UPF0761 family
HCIEOBLE_03813 4.1e-50 yfkI S gas vesicle protein
HCIEOBLE_03814 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCIEOBLE_03815 1.3e-28 yfkK S Belongs to the UPF0435 family
HCIEOBLE_03816 3.8e-205 ydiM EGP Major facilitator Superfamily
HCIEOBLE_03817 4.7e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
HCIEOBLE_03818 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HCIEOBLE_03819 1.1e-124 yfkO C nitroreductase
HCIEOBLE_03820 6.7e-133 treR K transcriptional
HCIEOBLE_03821 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HCIEOBLE_03822 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCIEOBLE_03823 2.2e-25 yfkQ EG Spore germination protein
HCIEOBLE_03824 2.2e-252 agcS_1 E Sodium alanine symporter
HCIEOBLE_03825 6e-67 yhdN S Domain of unknown function (DUF1992)
HCIEOBLE_03826 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HCIEOBLE_03827 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HCIEOBLE_03828 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HCIEOBLE_03829 2.4e-50 yflH S Protein of unknown function (DUF3243)
HCIEOBLE_03830 4.1e-19 yflI
HCIEOBLE_03831 4e-18 yflJ S Protein of unknown function (DUF2639)
HCIEOBLE_03832 9.9e-123 yflK S protein conserved in bacteria
HCIEOBLE_03833 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HCIEOBLE_03834 2.5e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HCIEOBLE_03835 1.8e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HCIEOBLE_03836 2.5e-226 citM C Citrate transporter
HCIEOBLE_03837 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
HCIEOBLE_03838 5.8e-118 citT T response regulator
HCIEOBLE_03839 1.4e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HCIEOBLE_03840 1.2e-234 yflS P Sodium:sulfate symporter transmembrane region
HCIEOBLE_03841 4.2e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HCIEOBLE_03842 7.6e-58 yflT S Heat induced stress protein YflT
HCIEOBLE_03843 2.9e-24 S Protein of unknown function (DUF3212)
HCIEOBLE_03844 2.1e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HCIEOBLE_03845 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_03846 2.1e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIEOBLE_03847 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HCIEOBLE_03848 6.1e-188 yfmJ S N-terminal domain of oxidoreductase
HCIEOBLE_03849 8e-76 yfmK 2.3.1.128 K acetyltransferase
HCIEOBLE_03850 2.9e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HCIEOBLE_03851 2.1e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HCIEOBLE_03852 1.5e-209 yfmO EGP Major facilitator Superfamily
HCIEOBLE_03853 2.8e-70 yfmP K transcriptional
HCIEOBLE_03854 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
HCIEOBLE_03855 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HCIEOBLE_03856 5.4e-113 yfmS NT chemotaxis protein
HCIEOBLE_03857 3.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCIEOBLE_03858 1.2e-239 yfnA E amino acid
HCIEOBLE_03859 8.1e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCIEOBLE_03860 1.9e-204 fsr P COG0477 Permeases of the major facilitator superfamily
HCIEOBLE_03861 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
HCIEOBLE_03862 5.5e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HCIEOBLE_03863 1.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
HCIEOBLE_03864 1.9e-172 yfnG 4.2.1.45 M dehydratase
HCIEOBLE_03865 1.1e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
HCIEOBLE_03867 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HCIEOBLE_03868 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HCIEOBLE_03869 2.3e-198 yetN S Protein of unknown function (DUF3900)
HCIEOBLE_03870 1e-49 yetL K helix_turn_helix multiple antibiotic resistance protein
HCIEOBLE_03871 5.3e-105 yetJ S Belongs to the BI1 family
HCIEOBLE_03872 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HCIEOBLE_03873 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HCIEOBLE_03874 2.4e-34
HCIEOBLE_03875 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCIEOBLE_03876 8.2e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HCIEOBLE_03877 5.2e-122 yetF S membrane
HCIEOBLE_03878 2.7e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HCIEOBLE_03879 5e-162 lplC G Binding-protein-dependent transport system inner membrane component
HCIEOBLE_03880 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HCIEOBLE_03881 6.2e-290 lplA G Bacterial extracellular solute-binding protein
HCIEOBLE_03882 0.0 yetA
HCIEOBLE_03883 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HCIEOBLE_03884 4e-124 yesY E GDSL-like Lipase/Acylhydrolase
HCIEOBLE_03885 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HCIEOBLE_03886 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HCIEOBLE_03887 8.8e-113 yesV S Protein of unknown function, DUF624
HCIEOBLE_03888 2.7e-128 yesU S Domain of unknown function (DUF1961)
HCIEOBLE_03889 1.7e-128 E GDSL-like Lipase/Acylhydrolase
HCIEOBLE_03890 0.0 yesS K Transcriptional regulator
HCIEOBLE_03891 2.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HCIEOBLE_03892 2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
HCIEOBLE_03893 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HCIEOBLE_03894 1.6e-246 yesO G Bacterial extracellular solute-binding protein
HCIEOBLE_03895 3.6e-202 yesN K helix_turn_helix, arabinose operon control protein
HCIEOBLE_03896 0.0 yesM 2.7.13.3 T Histidine kinase
HCIEOBLE_03897 1.2e-101 yesL S Protein of unknown function, DUF624
HCIEOBLE_03899 3.9e-101 yesJ K Acetyltransferase (GNAT) family
HCIEOBLE_03900 5.2e-104 cotJC P Spore Coat
HCIEOBLE_03901 1.5e-45 cotJB S CotJB protein
HCIEOBLE_03902 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HCIEOBLE_03903 2.1e-149 yesF GM NAD(P)H-binding
HCIEOBLE_03904 2.8e-81 yesE S SnoaL-like domain
HCIEOBLE_03905 3.6e-100 dhaR3 K Transcriptional regulator
HCIEOBLE_03907 9.4e-127 yeeN K transcriptional regulatory protein
HCIEOBLE_03909 2.8e-210 S Tetratricopeptide repeat
HCIEOBLE_03910 1.8e-39
HCIEOBLE_03911 3.8e-174 3.4.24.40 CO amine dehydrogenase activity
HCIEOBLE_03912 0.0 L nucleic acid phosphodiester bond hydrolysis
HCIEOBLE_03913 2.2e-52 S Protein of unknown function, DUF600
HCIEOBLE_03914 4.5e-61 S Protein of unknown function, DUF600
HCIEOBLE_03915 5.4e-70 S Protein of unknown function, DUF600
HCIEOBLE_03916 5.9e-56 S Protein of unknown function, DUF600
HCIEOBLE_03917 7.4e-45 S Protein of unknown function, DUF600
HCIEOBLE_03918 3.9e-38 S Protein of unknown function, DUF600
HCIEOBLE_03919 2.8e-35
HCIEOBLE_03920 1.1e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCIEOBLE_03921 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HCIEOBLE_03922 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HCIEOBLE_03923 5.9e-144 yerO K Transcriptional regulator
HCIEOBLE_03924 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCIEOBLE_03925 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCIEOBLE_03926 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCIEOBLE_03927 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCIEOBLE_03928 3.6e-123 sapB S MgtC SapB transporter
HCIEOBLE_03929 6.6e-195 yerI S homoserine kinase type II (protein kinase fold)
HCIEOBLE_03930 3e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
HCIEOBLE_03931 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCIEOBLE_03932 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HCIEOBLE_03933 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HCIEOBLE_03935 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HCIEOBLE_03936 4.8e-51 yerC S protein conserved in bacteria
HCIEOBLE_03937 5.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
HCIEOBLE_03938 0.0 yerA 3.5.4.2 F adenine deaminase
HCIEOBLE_03939 2.7e-27 S Protein of unknown function (DUF2892)
HCIEOBLE_03940 4.1e-227 yjeH E Amino acid permease
HCIEOBLE_03941 1.1e-71 K helix_turn_helix ASNC type
HCIEOBLE_03942 1.7e-232 purD 6.3.4.13 F Belongs to the GARS family
HCIEOBLE_03943 1.1e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HCIEOBLE_03944 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCIEOBLE_03945 3.2e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HCIEOBLE_03946 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCIEOBLE_03947 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCIEOBLE_03948 5.6e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCIEOBLE_03949 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCIEOBLE_03950 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HCIEOBLE_03951 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCIEOBLE_03952 2e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCIEOBLE_03953 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCIEOBLE_03954 8e-28 yebG S NETI protein
HCIEOBLE_03955 4e-93 yebE S UPF0316 protein
HCIEOBLE_03957 2.3e-118 yebC M Membrane
HCIEOBLE_03958 3e-211 pbuG S permease
HCIEOBLE_03959 2.1e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HCIEOBLE_03960 0.0 yebA E COG1305 Transglutaminase-like enzymes
HCIEOBLE_03961 3.6e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HCIEOBLE_03962 1.4e-173 yeaC S COG0714 MoxR-like ATPases
HCIEOBLE_03963 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCIEOBLE_03964 9.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HCIEOBLE_03965 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HCIEOBLE_03966 1.6e-177 yeaA S Protein of unknown function (DUF4003)
HCIEOBLE_03967 3.1e-158 ydjP I Alpha/beta hydrolase family
HCIEOBLE_03968 1.2e-34 ydjO S Cold-inducible protein YdjO
HCIEOBLE_03970 1.1e-155 ydjN U Involved in the tonB-independent uptake of proteins
HCIEOBLE_03971 4.5e-64 ydjM M Lytic transglycolase
HCIEOBLE_03972 4.9e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HCIEOBLE_03973 1.7e-257 iolT EGP Major facilitator Superfamily
HCIEOBLE_03974 4.7e-196 S Ion transport 2 domain protein
HCIEOBLE_03975 7.6e-148 ydjI S virion core protein (lumpy skin disease virus)
HCIEOBLE_03976 6.5e-134 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HCIEOBLE_03977 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCIEOBLE_03978 1.6e-112 pspA KT Phage shock protein A
HCIEOBLE_03979 4e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HCIEOBLE_03980 2.3e-254 gutA G MFS/sugar transport protein
HCIEOBLE_03981 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
HCIEOBLE_03982 0.0 K NB-ARC domain
HCIEOBLE_03983 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HCIEOBLE_03984 2.2e-131 3.1.21.3 V Type I restriction modification DNA specificity domain
HCIEOBLE_03985 5.6e-289 hsdM 2.1.1.72 V Type I restriction-modification system
HCIEOBLE_03986 3.1e-80 3.1.21.3 V Type I restriction modification DNA specificity domain
HCIEOBLE_03987 5.1e-64 yozB S Membrane
HCIEOBLE_03990 5.4e-235 yobL S Bacterial EndoU nuclease
HCIEOBLE_03991 4.1e-40
HCIEOBLE_03993 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCIEOBLE_03994 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCIEOBLE_03995 7.9e-129 ydiL S CAAX protease self-immunity
HCIEOBLE_03996 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HCIEOBLE_03997 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HCIEOBLE_03998 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HCIEOBLE_03999 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCIEOBLE_04000 2.1e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HCIEOBLE_04001 0.0 ydiF S ABC transporter
HCIEOBLE_04002 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCIEOBLE_04003 1.8e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HCIEOBLE_04004 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HCIEOBLE_04005 3.8e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HCIEOBLE_04006 5.3e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HCIEOBLE_04008 2.9e-76 ctsR K Belongs to the CtsR family
HCIEOBLE_04009 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HCIEOBLE_04010 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HCIEOBLE_04011 0.0 clpC O Belongs to the ClpA ClpB family
HCIEOBLE_04012 3.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCIEOBLE_04013 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HCIEOBLE_04014 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HCIEOBLE_04015 1.9e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HCIEOBLE_04016 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HCIEOBLE_04017 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCIEOBLE_04018 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HCIEOBLE_04019 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCIEOBLE_04020 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCIEOBLE_04021 7.5e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCIEOBLE_04022 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HCIEOBLE_04023 4.4e-115 sigH K Belongs to the sigma-70 factor family
HCIEOBLE_04024 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCIEOBLE_04025 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HCIEOBLE_04026 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCIEOBLE_04027 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCIEOBLE_04028 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCIEOBLE_04029 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCIEOBLE_04030 4.5e-106 rsmC 2.1.1.172 J Methyltransferase
HCIEOBLE_04031 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCIEOBLE_04032 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCIEOBLE_04033 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HCIEOBLE_04034 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCIEOBLE_04035 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCIEOBLE_04036 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCIEOBLE_04037 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCIEOBLE_04038 4e-181 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HCIEOBLE_04039 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HCIEOBLE_04040 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCIEOBLE_04041 3e-105 rplD J Forms part of the polypeptide exit tunnel
HCIEOBLE_04042 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCIEOBLE_04043 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCIEOBLE_04044 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCIEOBLE_04045 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCIEOBLE_04046 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCIEOBLE_04047 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCIEOBLE_04048 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HCIEOBLE_04049 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCIEOBLE_04050 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCIEOBLE_04051 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCIEOBLE_04052 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCIEOBLE_04053 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCIEOBLE_04054 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCIEOBLE_04055 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCIEOBLE_04056 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCIEOBLE_04057 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCIEOBLE_04058 1.9e-23 rpmD J Ribosomal protein L30
HCIEOBLE_04059 1.8e-72 rplO J binds to the 23S rRNA
HCIEOBLE_04060 5.5e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCIEOBLE_04061 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCIEOBLE_04062 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HCIEOBLE_04063 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCIEOBLE_04064 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HCIEOBLE_04065 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCIEOBLE_04066 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCIEOBLE_04067 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCIEOBLE_04068 3.6e-58 rplQ J Ribosomal protein L17
HCIEOBLE_04069 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCIEOBLE_04070 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCIEOBLE_04071 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCIEOBLE_04072 2.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCIEOBLE_04073 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCIEOBLE_04074 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HCIEOBLE_04075 2e-143 ybaJ Q Methyltransferase domain
HCIEOBLE_04076 2.8e-65 ybaK S Protein of unknown function (DUF2521)
HCIEOBLE_04077 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCIEOBLE_04078 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HCIEOBLE_04079 1.2e-84 gerD
HCIEOBLE_04080 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HCIEOBLE_04081 2.7e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HCIEOBLE_04082 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HCIEOBLE_04083 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCIEOBLE_04084 4.1e-30 yazB K transcriptional
HCIEOBLE_04085 1.1e-86 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HCIEOBLE_04086 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCIEOBLE_04087 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HCIEOBLE_04088 4.3e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HCIEOBLE_04089 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HCIEOBLE_04090 2.8e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCIEOBLE_04091 7.5e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HCIEOBLE_04092 5e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HCIEOBLE_04093 6.4e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCIEOBLE_04094 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HCIEOBLE_04095 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCIEOBLE_04096 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HCIEOBLE_04097 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCIEOBLE_04098 3.7e-185 KLT serine threonine protein kinase
HCIEOBLE_04099 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HCIEOBLE_04100 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HCIEOBLE_04103 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HCIEOBLE_04104 1.1e-44 divIC D Septum formation initiator
HCIEOBLE_04105 9.5e-107 yabQ S spore cortex biosynthesis protein
HCIEOBLE_04106 1.5e-49 yabP S Sporulation protein YabP
HCIEOBLE_04107 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HCIEOBLE_04108 3.6e-242 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HCIEOBLE_04109 3e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCIEOBLE_04110 1.5e-92 spoVT K stage V sporulation protein
HCIEOBLE_04111 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCIEOBLE_04112 2.4e-39 yabK S Peptide ABC transporter permease
HCIEOBLE_04113 4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCIEOBLE_04114 4.3e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HCIEOBLE_04115 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCIEOBLE_04116 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCIEOBLE_04117 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HCIEOBLE_04118 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HCIEOBLE_04119 7.7e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HCIEOBLE_04120 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCIEOBLE_04121 8.3e-27 sspF S DNA topological change
HCIEOBLE_04122 7.8e-39 veg S protein conserved in bacteria
HCIEOBLE_04123 1.6e-136 yabG S peptidase
HCIEOBLE_04124 5.8e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCIEOBLE_04125 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCIEOBLE_04126 6.9e-168 rpfB GH23 T protein conserved in bacteria
HCIEOBLE_04127 1.2e-143 tatD L hydrolase, TatD
HCIEOBLE_04128 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCIEOBLE_04129 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HCIEOBLE_04130 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCIEOBLE_04131 1.5e-49 yazA L endonuclease containing a URI domain
HCIEOBLE_04132 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HCIEOBLE_04133 4.8e-31 yabA L Involved in initiation control of chromosome replication
HCIEOBLE_04134 6.1e-146 yaaT S stage 0 sporulation protein
HCIEOBLE_04135 1.1e-181 holB 2.7.7.7 L DNA polymerase III
HCIEOBLE_04136 1.5e-71 yaaR S protein conserved in bacteria
HCIEOBLE_04137 2.2e-54 yaaQ S protein conserved in bacteria
HCIEOBLE_04138 2.1e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCIEOBLE_04139 7.8e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HCIEOBLE_04140 2.9e-202 yaaN P Belongs to the TelA family
HCIEOBLE_04141 8.4e-100 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HCIEOBLE_04142 3.4e-31 csfB S Inhibitor of sigma-G Gin
HCIEOBLE_04143 2.3e-181 yaaC S YaaC-like Protein
HCIEOBLE_04144 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HCIEOBLE_04145 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HCIEOBLE_04146 6.3e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HCIEOBLE_04147 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HCIEOBLE_04148 6.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCIEOBLE_04149 1.3e-09
HCIEOBLE_04150 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HCIEOBLE_04151 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HCIEOBLE_04152 1.2e-212 yaaH M Glycoside Hydrolase Family
HCIEOBLE_04153 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
HCIEOBLE_04154 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCIEOBLE_04155 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCIEOBLE_04156 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCIEOBLE_04157 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCIEOBLE_04158 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HCIEOBLE_04159 1.8e-35 bofA S Sigma-K factor-processing regulatory protein BofA
HCIEOBLE_04160 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)