ORF_ID e_value Gene_name EC_number CAZy COGs Description
HDKPDFJJ_00001 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDKPDFJJ_00002 3.4e-39 S COG NOG14552 non supervised orthologous group
HDKPDFJJ_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDKPDFJJ_00008 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDKPDFJJ_00009 1.8e-37 yaaB S Domain of unknown function (DUF370)
HDKPDFJJ_00010 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDKPDFJJ_00011 2.4e-33 yaaA S S4 domain
HDKPDFJJ_00012 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDKPDFJJ_00013 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDKPDFJJ_00014 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDKPDFJJ_00015 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDKPDFJJ_00016 6.5e-108 jag S single-stranded nucleic acid binding R3H
HDKPDFJJ_00017 5.4e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDKPDFJJ_00018 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDKPDFJJ_00019 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HDKPDFJJ_00020 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HDKPDFJJ_00021 3.7e-73 S Bacterial PH domain
HDKPDFJJ_00022 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HDKPDFJJ_00023 2.1e-149 spo0J K Belongs to the ParB family
HDKPDFJJ_00024 1.6e-111 yyaC S Sporulation protein YyaC
HDKPDFJJ_00025 4e-176 yyaD S Membrane
HDKPDFJJ_00026 2.3e-33 yyzM S protein conserved in bacteria
HDKPDFJJ_00027 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDKPDFJJ_00028 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDKPDFJJ_00029 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
HDKPDFJJ_00030 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDKPDFJJ_00031 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDKPDFJJ_00032 2.2e-142 xth 3.1.11.2 L exodeoxyribonuclease III
HDKPDFJJ_00033 1.7e-176 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HDKPDFJJ_00034 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDKPDFJJ_00035 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HDKPDFJJ_00036 1.8e-243 EGP Major facilitator superfamily
HDKPDFJJ_00037 3.4e-166 yyaK S CAAX protease self-immunity
HDKPDFJJ_00038 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HDKPDFJJ_00039 4.4e-24 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HDKPDFJJ_00042 1.4e-66 S response regulator aspartate phosphatase
HDKPDFJJ_00044 1.9e-44 immA E IrrE N-terminal-like domain
HDKPDFJJ_00045 1.4e-41 yvaO K Transcriptional
HDKPDFJJ_00046 6e-14
HDKPDFJJ_00047 4.7e-36
HDKPDFJJ_00049 6e-64 S Bacterial protein of unknown function (DUF961)
HDKPDFJJ_00050 2.6e-71
HDKPDFJJ_00051 3.6e-263 ydcQ D Ftsk spoiiie family protein
HDKPDFJJ_00052 7.7e-202 nicK L Replication initiation factor
HDKPDFJJ_00055 8e-42 yddA
HDKPDFJJ_00057 1.3e-164 yddB S Conjugative transposon protein TcpC
HDKPDFJJ_00058 5.1e-40 yddC
HDKPDFJJ_00059 2e-94 yddD S TcpE family
HDKPDFJJ_00060 0.0 yddE S AAA-like domain
HDKPDFJJ_00061 4.9e-54 S Domain of unknown function (DUF1874)
HDKPDFJJ_00062 0.0 yddG S maturation of SSU-rRNA
HDKPDFJJ_00063 4.5e-188 yddH CBM50 M Lysozyme-like
HDKPDFJJ_00064 2.4e-84 yddI
HDKPDFJJ_00065 5.1e-63 S Domain of unknown function with cystatin-like fold (DUF4467)
HDKPDFJJ_00067 1.1e-55 L Recombinase
HDKPDFJJ_00068 1.1e-136 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HDKPDFJJ_00069 8.4e-38 ydeP K HxlR-like helix-turn-helix
HDKPDFJJ_00070 1.9e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HDKPDFJJ_00071 6.3e-160 yyaM EG EamA-like transporter family
HDKPDFJJ_00072 2.5e-60 yyaN K MerR HTH family regulatory protein
HDKPDFJJ_00073 1.2e-41 yyaL O Highly conserved protein containing a thioredoxin domain
HDKPDFJJ_00074 6.6e-246 tetL EGP Major facilitator Superfamily
HDKPDFJJ_00075 3.6e-105 yyaP 1.5.1.3 H RibD C-terminal domain
HDKPDFJJ_00076 7.8e-66 yyaQ S YjbR
HDKPDFJJ_00077 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
HDKPDFJJ_00078 5.5e-96 yyaS S Membrane
HDKPDFJJ_00079 1.3e-70 yjcF S Acetyltransferase (GNAT) domain
HDKPDFJJ_00080 5.6e-77 yybA 2.3.1.57 K transcriptional
HDKPDFJJ_00081 3e-127 S Metallo-beta-lactamase superfamily
HDKPDFJJ_00082 1.5e-75 yybC
HDKPDFJJ_00083 2e-79 yjcF S Acetyltransferase (GNAT) domain
HDKPDFJJ_00084 4.5e-163 yybE K Transcriptional regulator
HDKPDFJJ_00085 8.8e-218 ynfM EGP Major facilitator Superfamily
HDKPDFJJ_00086 6.2e-122 yybG S Pentapeptide repeat-containing protein
HDKPDFJJ_00087 1.9e-65 yybH S SnoaL-like domain
HDKPDFJJ_00088 3.5e-122
HDKPDFJJ_00089 4.8e-110 K TipAS antibiotic-recognition domain
HDKPDFJJ_00090 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HDKPDFJJ_00092 5.6e-61
HDKPDFJJ_00093 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HDKPDFJJ_00094 1.7e-66 ydeP3 K Transcriptional regulator
HDKPDFJJ_00095 3.9e-84 cotF M Spore coat protein
HDKPDFJJ_00097 1.1e-159 yybS S membrane
HDKPDFJJ_00098 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HDKPDFJJ_00099 4.9e-73 rplI J binds to the 23S rRNA
HDKPDFJJ_00100 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDKPDFJJ_00101 8.4e-221 yeaN P COG2807 Cyanate permease
HDKPDFJJ_00102 1.9e-15 yycC K YycC-like protein
HDKPDFJJ_00104 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HDKPDFJJ_00105 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HDKPDFJJ_00106 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDKPDFJJ_00107 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDKPDFJJ_00112 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_00113 0.0 vicK 2.7.13.3 T Histidine kinase
HDKPDFJJ_00114 4.9e-257 yycH S protein conserved in bacteria
HDKPDFJJ_00115 7.3e-155 yycI S protein conserved in bacteria
HDKPDFJJ_00116 4.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HDKPDFJJ_00117 1.9e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDKPDFJJ_00118 3.8e-34 S Peptidase propeptide and YPEB domain
HDKPDFJJ_00119 1.2e-73 S Peptidase propeptide and YPEB domain
HDKPDFJJ_00120 3.4e-94 K PFAM response regulator receiver
HDKPDFJJ_00121 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HDKPDFJJ_00122 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HDKPDFJJ_00123 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HDKPDFJJ_00124 1.4e-254 rocE E amino acid
HDKPDFJJ_00125 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HDKPDFJJ_00127 1.1e-187 S aspartate phosphatase
HDKPDFJJ_00128 8.4e-84 yycN 2.3.1.128 K Acetyltransferase
HDKPDFJJ_00129 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HDKPDFJJ_00130 3.9e-207 yycP
HDKPDFJJ_00131 8.2e-30 yycQ S Protein of unknown function (DUF2651)
HDKPDFJJ_00133 6.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HDKPDFJJ_00134 8.2e-59
HDKPDFJJ_00135 1.1e-09 S YyzF-like protein
HDKPDFJJ_00136 4.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDKPDFJJ_00137 4.4e-112 K competence protein
HDKPDFJJ_00138 1.8e-22 2.7.7.49 L Reverse transcriptase (RNA-dependent DNA polymerase)
HDKPDFJJ_00139 1.1e-154 2.7.7.49 L Reverse transcriptase (RNA-dependent DNA polymerase)
HDKPDFJJ_00140 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HDKPDFJJ_00141 5.9e-109 prrC P ABC transporter
HDKPDFJJ_00142 9.5e-119 S ABC-2 family transporter protein
HDKPDFJJ_00143 8.4e-12
HDKPDFJJ_00144 1.6e-123 yydK K Transcriptional regulator
HDKPDFJJ_00145 1.3e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDKPDFJJ_00146 5.6e-189 wgaE S Polysaccharide pyruvyl transferase
HDKPDFJJ_00147 2.5e-286 ahpF O Alkyl hydroperoxide reductase
HDKPDFJJ_00148 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HDKPDFJJ_00149 4.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDKPDFJJ_00150 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HDKPDFJJ_00151 1.7e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HDKPDFJJ_00152 7.3e-127 gntR K transcriptional
HDKPDFJJ_00153 4.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HDKPDFJJ_00154 5.9e-191 yxaB GM Polysaccharide pyruvyl transferase
HDKPDFJJ_00155 2.6e-118 yxaC M effector of murein hydrolase
HDKPDFJJ_00156 5.2e-50 S LrgA family
HDKPDFJJ_00157 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HDKPDFJJ_00158 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_00159 2.7e-100 yxaF K Transcriptional regulator
HDKPDFJJ_00160 6.4e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
HDKPDFJJ_00161 4.6e-227 P Protein of unknown function (DUF418)
HDKPDFJJ_00162 1.4e-75 yxaI S membrane protein domain
HDKPDFJJ_00163 1.1e-63 S Family of unknown function (DUF5391)
HDKPDFJJ_00164 8.3e-91 S PQQ-like domain
HDKPDFJJ_00165 6.4e-25 yxaI S membrane protein domain
HDKPDFJJ_00166 1.2e-244 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HDKPDFJJ_00167 4.5e-208 yxbF K Bacterial regulatory proteins, tetR family
HDKPDFJJ_00168 3.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
HDKPDFJJ_00170 0.0 htpG O Molecular chaperone. Has ATPase activity
HDKPDFJJ_00171 1.5e-245 csbC EGP Major facilitator Superfamily
HDKPDFJJ_00172 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HDKPDFJJ_00174 4.1e-175 iolS C Aldo keto reductase
HDKPDFJJ_00175 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HDKPDFJJ_00176 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDKPDFJJ_00177 1.6e-151 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HDKPDFJJ_00178 7.9e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HDKPDFJJ_00179 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HDKPDFJJ_00180 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HDKPDFJJ_00181 5.1e-235 iolF EGP Major facilitator Superfamily
HDKPDFJJ_00182 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HDKPDFJJ_00183 3e-167 iolH G Xylose isomerase-like TIM barrel
HDKPDFJJ_00184 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HDKPDFJJ_00185 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HDKPDFJJ_00186 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_00187 1.1e-178 T PhoQ Sensor
HDKPDFJJ_00188 3.7e-137 yxdL V ABC transporter, ATP-binding protein
HDKPDFJJ_00189 0.0 yxdM V ABC transporter (permease)
HDKPDFJJ_00190 1.3e-57 yxeA S Protein of unknown function (DUF1093)
HDKPDFJJ_00191 1.1e-175 fhuD P ABC transporter
HDKPDFJJ_00192 8.5e-69
HDKPDFJJ_00193 5.6e-16 yxeD
HDKPDFJJ_00194 2.5e-14 yxeE
HDKPDFJJ_00197 1.5e-149 yidA S hydrolases of the HAD superfamily
HDKPDFJJ_00198 1.4e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HDKPDFJJ_00199 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDKPDFJJ_00200 1.6e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDKPDFJJ_00201 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HDKPDFJJ_00202 1.2e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
HDKPDFJJ_00203 1.7e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HDKPDFJJ_00204 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
HDKPDFJJ_00205 8.6e-251 yxeQ S MmgE/PrpD family
HDKPDFJJ_00206 5.1e-196 eutH E Ethanolamine utilisation protein, EutH
HDKPDFJJ_00207 2e-152 yxxB S Domain of Unknown Function (DUF1206)
HDKPDFJJ_00208 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HDKPDFJJ_00209 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDKPDFJJ_00210 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HDKPDFJJ_00211 8.7e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HDKPDFJJ_00212 3.4e-250 lysP E amino acid
HDKPDFJJ_00213 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HDKPDFJJ_00214 4.4e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HDKPDFJJ_00215 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HDKPDFJJ_00216 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
HDKPDFJJ_00217 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HDKPDFJJ_00218 2.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HDKPDFJJ_00219 1.1e-58 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HDKPDFJJ_00221 0.0 L HKD family nuclease
HDKPDFJJ_00222 2.3e-20 S Domain of unknown function (DUF5082)
HDKPDFJJ_00223 1.4e-38 yxiC S Family of unknown function (DUF5344)
HDKPDFJJ_00224 6.4e-216 S nuclease activity
HDKPDFJJ_00225 5.5e-53
HDKPDFJJ_00226 2.6e-306 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDKPDFJJ_00227 2e-277 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDKPDFJJ_00228 5.4e-72 yxiE T Belongs to the universal stress protein A family
HDKPDFJJ_00229 1.9e-164 yxxF EG EamA-like transporter family
HDKPDFJJ_00230 0.0 wapA M COG3209 Rhs family protein
HDKPDFJJ_00231 1.5e-71 yxxG
HDKPDFJJ_00232 1.1e-83
HDKPDFJJ_00233 7.3e-59
HDKPDFJJ_00234 5.1e-69 yxiG
HDKPDFJJ_00235 4.4e-139
HDKPDFJJ_00236 8.7e-84 yxiI S Protein of unknown function (DUF2716)
HDKPDFJJ_00237 7.3e-41 yxiJ S YxiJ-like protein
HDKPDFJJ_00240 6.5e-61 S Protein of unknown function (DUF2812)
HDKPDFJJ_00241 7.8e-55 padR K Transcriptional regulator PadR-like family
HDKPDFJJ_00242 1e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HDKPDFJJ_00243 1.3e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HDKPDFJJ_00244 1.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
HDKPDFJJ_00245 7.6e-110
HDKPDFJJ_00246 8.3e-151 licT K transcriptional antiterminator
HDKPDFJJ_00247 1.1e-143 exoK GH16 M licheninase activity
HDKPDFJJ_00248 6.6e-224 citH C Citrate transporter
HDKPDFJJ_00249 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HDKPDFJJ_00250 3e-47 yxiS
HDKPDFJJ_00251 1.2e-104 T Domain of unknown function (DUF4163)
HDKPDFJJ_00252 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HDKPDFJJ_00253 1.4e-141 rlmA 2.1.1.187 Q Methyltransferase domain
HDKPDFJJ_00254 4.9e-252 yxjC EG COG2610 H gluconate symporter and related permeases
HDKPDFJJ_00255 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HDKPDFJJ_00256 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HDKPDFJJ_00257 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HDKPDFJJ_00258 1.7e-218 yxjG 2.1.1.14 E Methionine synthase
HDKPDFJJ_00259 1.4e-217 yxjG 2.1.1.14 E Methionine synthase
HDKPDFJJ_00260 1.3e-84 yxjI S LURP-one-related
HDKPDFJJ_00263 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDKPDFJJ_00264 2.9e-114 K helix_turn_helix, Lux Regulon
HDKPDFJJ_00265 2.4e-191 yxjM T Signal transduction histidine kinase
HDKPDFJJ_00266 2e-77 S Protein of unknown function (DUF1453)
HDKPDFJJ_00267 3.9e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDKPDFJJ_00268 1.4e-73 yxkC S Domain of unknown function (DUF4352)
HDKPDFJJ_00269 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDKPDFJJ_00270 2.2e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDKPDFJJ_00271 3.5e-163 lrp QT PucR C-terminal helix-turn-helix domain
HDKPDFJJ_00272 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HDKPDFJJ_00273 2.1e-154 yxkH G Polysaccharide deacetylase
HDKPDFJJ_00275 9.4e-311 3.4.24.84 O Peptidase family M48
HDKPDFJJ_00276 1.5e-229 cimH C COG3493 Na citrate symporter
HDKPDFJJ_00277 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
HDKPDFJJ_00278 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HDKPDFJJ_00279 1.7e-310 cydD V ATP-binding
HDKPDFJJ_00280 0.0 cydD V ATP-binding protein
HDKPDFJJ_00281 7.7e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDKPDFJJ_00282 1.1e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HDKPDFJJ_00283 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HDKPDFJJ_00284 3.9e-48 yxlC S Family of unknown function (DUF5345)
HDKPDFJJ_00285 1.4e-30
HDKPDFJJ_00286 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HDKPDFJJ_00287 4.8e-165 yxlF V ABC transporter, ATP-binding protein
HDKPDFJJ_00288 3.4e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HDKPDFJJ_00289 8.7e-210 yxlH EGP Major facilitator Superfamily
HDKPDFJJ_00290 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HDKPDFJJ_00291 1.1e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HDKPDFJJ_00292 1.1e-19 yxzF
HDKPDFJJ_00293 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HDKPDFJJ_00294 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HDKPDFJJ_00295 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDKPDFJJ_00296 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HDKPDFJJ_00297 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HDKPDFJJ_00298 1.2e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HDKPDFJJ_00299 2.5e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_00300 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDKPDFJJ_00301 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDKPDFJJ_00302 1.2e-232 dltB M membrane protein involved in D-alanine export
HDKPDFJJ_00303 1.1e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDKPDFJJ_00304 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
HDKPDFJJ_00305 5.1e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HDKPDFJJ_00306 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HDKPDFJJ_00307 5.2e-130 ynfM EGP Major facilitator Superfamily
HDKPDFJJ_00308 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
HDKPDFJJ_00309 5.3e-92 K Helix-turn-helix XRE-family like proteins
HDKPDFJJ_00310 8.8e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HDKPDFJJ_00311 6.6e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDKPDFJJ_00312 4e-87 ywaE K Transcriptional regulator
HDKPDFJJ_00313 1.3e-123 ywaF S Integral membrane protein
HDKPDFJJ_00314 4.5e-168 gspA M General stress
HDKPDFJJ_00315 9.9e-152 sacY K transcriptional antiterminator
HDKPDFJJ_00316 2e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDKPDFJJ_00317 9.2e-270 epr 3.4.21.62 O Belongs to the peptidase S8 family
HDKPDFJJ_00318 7.7e-172 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDKPDFJJ_00319 5.2e-50 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDKPDFJJ_00320 6.1e-120 ywbB S Protein of unknown function (DUF2711)
HDKPDFJJ_00321 9.9e-67 ywbC 4.4.1.5 E glyoxalase
HDKPDFJJ_00322 2.4e-220 ywbD 2.1.1.191 J Methyltransferase
HDKPDFJJ_00323 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HDKPDFJJ_00324 1.3e-208 ywbF EGP Major facilitator Superfamily
HDKPDFJJ_00325 2.3e-111 ywbG M effector of murein hydrolase
HDKPDFJJ_00326 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HDKPDFJJ_00327 1.6e-152 ywbI K Transcriptional regulator
HDKPDFJJ_00328 4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HDKPDFJJ_00329 1.2e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HDKPDFJJ_00330 3e-249 P COG0672 High-affinity Fe2 Pb2 permease
HDKPDFJJ_00331 9.3e-185 ycdO P periplasmic lipoprotein involved in iron transport
HDKPDFJJ_00332 4.9e-224 ywbN P Dyp-type peroxidase family protein
HDKPDFJJ_00333 8.1e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HDKPDFJJ_00334 5.3e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDKPDFJJ_00335 2.9e-48 ywcB S Protein of unknown function, DUF485
HDKPDFJJ_00337 1.1e-121 ywcC K transcriptional regulator
HDKPDFJJ_00338 9.5e-60 gtcA S GtrA-like protein
HDKPDFJJ_00339 1.2e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDKPDFJJ_00340 1.9e-297 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HDKPDFJJ_00341 1e-35 ywzA S membrane
HDKPDFJJ_00342 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HDKPDFJJ_00343 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HDKPDFJJ_00344 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HDKPDFJJ_00345 1e-63 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HDKPDFJJ_00346 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HDKPDFJJ_00347 8.6e-202 rodA D Belongs to the SEDS family
HDKPDFJJ_00348 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HDKPDFJJ_00349 8.1e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDKPDFJJ_00350 0.0 vpr O Belongs to the peptidase S8 family
HDKPDFJJ_00352 7e-150 sacT K transcriptional antiterminator
HDKPDFJJ_00353 5.7e-138 focA P Formate/nitrite transporter
HDKPDFJJ_00354 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDKPDFJJ_00355 5.4e-291 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HDKPDFJJ_00356 2e-28 ywdA
HDKPDFJJ_00357 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HDKPDFJJ_00358 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HDKPDFJJ_00359 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDKPDFJJ_00360 6.1e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HDKPDFJJ_00361 1.3e-48 ywdI S Family of unknown function (DUF5327)
HDKPDFJJ_00362 3.7e-238 ywdJ F Xanthine uracil
HDKPDFJJ_00363 4.3e-59 ywdK S small membrane protein
HDKPDFJJ_00364 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HDKPDFJJ_00365 1e-142 spsA M Spore Coat
HDKPDFJJ_00366 5.6e-269 spsB M Capsule polysaccharide biosynthesis protein
HDKPDFJJ_00367 2.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
HDKPDFJJ_00368 2.2e-162 spsD 2.3.1.210 K Spore Coat
HDKPDFJJ_00369 7.1e-214 spsE 2.5.1.56 M acid synthase
HDKPDFJJ_00370 9.7e-132 spsF M Spore Coat
HDKPDFJJ_00371 7.9e-188 spsG M Spore Coat
HDKPDFJJ_00372 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HDKPDFJJ_00373 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDKPDFJJ_00374 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDKPDFJJ_00375 1.3e-86 spsL 5.1.3.13 M Spore Coat
HDKPDFJJ_00376 1.2e-77
HDKPDFJJ_00377 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HDKPDFJJ_00378 4.1e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HDKPDFJJ_00379 0.0 rocB E arginine degradation protein
HDKPDFJJ_00380 2.8e-249 lysP E amino acid
HDKPDFJJ_00381 1.3e-205 ywfA EGP Major facilitator Superfamily
HDKPDFJJ_00382 7.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HDKPDFJJ_00383 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HDKPDFJJ_00384 5.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDKPDFJJ_00385 3e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HDKPDFJJ_00386 1.9e-209 bacE EGP Major facilitator Superfamily
HDKPDFJJ_00387 6e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HDKPDFJJ_00388 7.5e-138 IQ Enoyl-(Acyl carrier protein) reductase
HDKPDFJJ_00389 3.3e-146 ywfI C May function as heme-dependent peroxidase
HDKPDFJJ_00390 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HDKPDFJJ_00391 1.1e-156 cysL K Transcriptional regulator
HDKPDFJJ_00392 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HDKPDFJJ_00393 2.2e-157 ywfM EG EamA-like transporter family
HDKPDFJJ_00394 5.1e-110 rsfA_1
HDKPDFJJ_00395 3.1e-36 ywzC S Belongs to the UPF0741 family
HDKPDFJJ_00396 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
HDKPDFJJ_00397 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HDKPDFJJ_00398 6.2e-79 yffB K Transcriptional regulator
HDKPDFJJ_00399 2.6e-237 mmr U Major Facilitator Superfamily
HDKPDFJJ_00401 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDKPDFJJ_00402 3.3e-71 ywhA K Transcriptional regulator
HDKPDFJJ_00403 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HDKPDFJJ_00404 5.1e-119 ywhC S Peptidase family M50
HDKPDFJJ_00405 2e-94 ywhD S YwhD family
HDKPDFJJ_00406 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDKPDFJJ_00407 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HDKPDFJJ_00408 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HDKPDFJJ_00409 1.6e-26 ywhH S Aminoacyl-tRNA editing domain
HDKPDFJJ_00411 3.1e-79 S aspartate phosphatase
HDKPDFJJ_00412 1.1e-189 ywhK CO amine dehydrogenase activity
HDKPDFJJ_00413 6.8e-243 ywhL CO amine dehydrogenase activity
HDKPDFJJ_00415 4.5e-249 L Peptidase, M16
HDKPDFJJ_00416 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
HDKPDFJJ_00417 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HDKPDFJJ_00418 3.3e-132 cbiO V ABC transporter
HDKPDFJJ_00420 6.4e-270 C Fe-S oxidoreductases
HDKPDFJJ_00421 1e-07 S Bacteriocin subtilosin A
HDKPDFJJ_00422 4.7e-73 ywiB S protein conserved in bacteria
HDKPDFJJ_00423 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HDKPDFJJ_00424 2.3e-213 narK P COG2223 Nitrate nitrite transporter
HDKPDFJJ_00425 5.9e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HDKPDFJJ_00426 1.7e-139 ywiC S YwiC-like protein
HDKPDFJJ_00427 7e-86 arfM T cyclic nucleotide binding
HDKPDFJJ_00428 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDKPDFJJ_00429 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
HDKPDFJJ_00430 3.6e-94 narJ 1.7.5.1 C nitrate reductase
HDKPDFJJ_00431 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
HDKPDFJJ_00432 1.9e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDKPDFJJ_00433 0.0 ywjA V ABC transporter
HDKPDFJJ_00434 2.5e-92 ywjB H RibD C-terminal domain
HDKPDFJJ_00435 6e-42 ywjC
HDKPDFJJ_00436 3.6e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HDKPDFJJ_00437 2.9e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HDKPDFJJ_00438 0.0 fadF C COG0247 Fe-S oxidoreductase
HDKPDFJJ_00439 7e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HDKPDFJJ_00440 5.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDKPDFJJ_00441 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDKPDFJJ_00442 1.8e-90 ywjG S Domain of unknown function (DUF2529)
HDKPDFJJ_00443 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HDKPDFJJ_00444 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HDKPDFJJ_00445 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HDKPDFJJ_00446 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDKPDFJJ_00447 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HDKPDFJJ_00448 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HDKPDFJJ_00449 1.1e-32 rpmE J Binds the 23S rRNA
HDKPDFJJ_00450 1.2e-103 tdk 2.7.1.21 F thymidine kinase
HDKPDFJJ_00451 0.0 sfcA 1.1.1.38 C malic enzyme
HDKPDFJJ_00452 8.6e-160 ywkB S Membrane transport protein
HDKPDFJJ_00453 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HDKPDFJJ_00454 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDKPDFJJ_00455 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDKPDFJJ_00456 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDKPDFJJ_00458 2.2e-55 ywlA S Uncharacterised protein family (UPF0715)
HDKPDFJJ_00459 6.1e-112 spoIIR S stage II sporulation protein R
HDKPDFJJ_00460 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HDKPDFJJ_00461 1.8e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDKPDFJJ_00462 1.7e-91 mntP P Probably functions as a manganese efflux pump
HDKPDFJJ_00463 3.6e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDKPDFJJ_00464 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HDKPDFJJ_00465 7.2e-95 ywlG S Belongs to the UPF0340 family
HDKPDFJJ_00466 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDKPDFJJ_00467 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDKPDFJJ_00468 7.4e-62 atpI S ATP synthase
HDKPDFJJ_00469 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HDKPDFJJ_00470 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDKPDFJJ_00471 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDKPDFJJ_00472 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDKPDFJJ_00473 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDKPDFJJ_00474 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDKPDFJJ_00475 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDKPDFJJ_00476 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HDKPDFJJ_00477 4.1e-86 ywmA
HDKPDFJJ_00478 2.8e-32 ywzB S membrane
HDKPDFJJ_00479 8.2e-134 ywmB S TATA-box binding
HDKPDFJJ_00480 3.9e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDKPDFJJ_00481 1.2e-175 spoIID D Stage II sporulation protein D
HDKPDFJJ_00482 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HDKPDFJJ_00483 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HDKPDFJJ_00485 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HDKPDFJJ_00486 5.9e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HDKPDFJJ_00487 1.3e-103 S response regulator aspartate phosphatase
HDKPDFJJ_00488 3e-84 ywmF S Peptidase M50
HDKPDFJJ_00489 3.8e-11 csbD K CsbD-like
HDKPDFJJ_00490 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HDKPDFJJ_00491 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HDKPDFJJ_00492 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HDKPDFJJ_00493 1.7e-64 ywnA K Transcriptional regulator
HDKPDFJJ_00494 1.1e-113 ywnB S NAD(P)H-binding
HDKPDFJJ_00495 1.7e-58 ywnC S Family of unknown function (DUF5362)
HDKPDFJJ_00496 2.2e-142 mta K transcriptional
HDKPDFJJ_00497 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDKPDFJJ_00498 2.9e-70 ywnF S Family of unknown function (DUF5392)
HDKPDFJJ_00499 3.4e-09 ywnC S Family of unknown function (DUF5362)
HDKPDFJJ_00500 2.7e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HDKPDFJJ_00501 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HDKPDFJJ_00502 5.6e-71 ywnJ S VanZ like family
HDKPDFJJ_00503 1.3e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HDKPDFJJ_00504 1.6e-58 nrgB K Belongs to the P(II) protein family
HDKPDFJJ_00505 3.3e-225 amt P Ammonium transporter
HDKPDFJJ_00506 1.2e-77
HDKPDFJJ_00507 6.8e-104 phzA Q Isochorismatase family
HDKPDFJJ_00508 9.1e-240 ywoD EGP Major facilitator superfamily
HDKPDFJJ_00509 2.8e-279 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HDKPDFJJ_00510 2.3e-225 ywoF P Right handed beta helix region
HDKPDFJJ_00512 1.7e-210 ywoG EGP Major facilitator Superfamily
HDKPDFJJ_00513 2.1e-70 ywoH K COG1846 Transcriptional regulators
HDKPDFJJ_00514 3e-44 spoIIID K Stage III sporulation protein D
HDKPDFJJ_00515 3.5e-180 mbl D Rod shape-determining protein
HDKPDFJJ_00516 5.8e-125 flhO N flagellar basal body
HDKPDFJJ_00517 8.3e-140 flhP N flagellar basal body
HDKPDFJJ_00518 5.7e-197 S aspartate phosphatase
HDKPDFJJ_00519 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDKPDFJJ_00520 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDKPDFJJ_00521 0.0 ywpD T PhoQ Sensor
HDKPDFJJ_00522 5.3e-174 M1-574 T Transcriptional regulatory protein, C terminal
HDKPDFJJ_00523 0.0 M1-568 M cell wall anchor domain
HDKPDFJJ_00524 4.1e-81 srtA 3.4.22.70 M Sortase family
HDKPDFJJ_00525 1.1e-66 ywpF S YwpF-like protein
HDKPDFJJ_00526 3.8e-66 ywpG
HDKPDFJJ_00527 3.7e-57 ssbB L Single-stranded DNA-binding protein
HDKPDFJJ_00528 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HDKPDFJJ_00529 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HDKPDFJJ_00530 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HDKPDFJJ_00531 2.7e-307 ywqB S SWIM zinc finger
HDKPDFJJ_00532 1.2e-17
HDKPDFJJ_00533 2e-116 ywqC M biosynthesis protein
HDKPDFJJ_00534 8.4e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HDKPDFJJ_00535 3.3e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HDKPDFJJ_00536 1.8e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDKPDFJJ_00537 1.4e-152 ywqG S Domain of unknown function (DUF1963)
HDKPDFJJ_00538 1.7e-19 S Domain of unknown function (DUF5082)
HDKPDFJJ_00539 3.1e-38 ywqI S Family of unknown function (DUF5344)
HDKPDFJJ_00540 2.9e-250 ywqJ S Pre-toxin TG
HDKPDFJJ_00541 4.2e-62
HDKPDFJJ_00542 5.2e-100
HDKPDFJJ_00543 4.1e-122 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HDKPDFJJ_00544 1.9e-161 K Transcriptional regulator
HDKPDFJJ_00545 3.5e-97 ywqN S NAD(P)H-dependent
HDKPDFJJ_00547 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
HDKPDFJJ_00548 2.7e-103 ywrB P Chromate transporter
HDKPDFJJ_00549 8e-82 ywrC K Transcriptional regulator
HDKPDFJJ_00550 2.2e-309 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HDKPDFJJ_00551 2.5e-53 S Domain of unknown function (DUF4181)
HDKPDFJJ_00552 1.5e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HDKPDFJJ_00553 1.3e-12
HDKPDFJJ_00554 6.2e-207 cotH M Spore Coat
HDKPDFJJ_00555 2.8e-123 cotB
HDKPDFJJ_00556 1.1e-124 ywrJ
HDKPDFJJ_00557 1.8e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HDKPDFJJ_00558 1.1e-169 alsR K LysR substrate binding domain
HDKPDFJJ_00559 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HDKPDFJJ_00560 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HDKPDFJJ_00561 2.8e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HDKPDFJJ_00562 8e-48 ywsA S Protein of unknown function (DUF3892)
HDKPDFJJ_00563 7.3e-92 batE T Sh3 type 3 domain protein
HDKPDFJJ_00564 7.2e-136 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HDKPDFJJ_00565 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HDKPDFJJ_00566 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HDKPDFJJ_00567 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HDKPDFJJ_00568 4.2e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDKPDFJJ_00569 5.5e-178 rbsR K transcriptional
HDKPDFJJ_00570 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HDKPDFJJ_00571 8.6e-70 pgsC S biosynthesis protein
HDKPDFJJ_00572 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HDKPDFJJ_00573 3.6e-21 ywtC
HDKPDFJJ_00574 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HDKPDFJJ_00575 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HDKPDFJJ_00576 2.4e-170 ywtF K Transcriptional regulator
HDKPDFJJ_00577 7.8e-247 ywtG EGP Major facilitator Superfamily
HDKPDFJJ_00578 5.8e-208 gerAC S Spore germination protein
HDKPDFJJ_00579 8.1e-194 gerBB E Spore germination protein
HDKPDFJJ_00580 5.7e-264 gerBA EG Spore germination protein
HDKPDFJJ_00581 2.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HDKPDFJJ_00582 2.3e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDKPDFJJ_00583 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDKPDFJJ_00584 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDKPDFJJ_00585 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HDKPDFJJ_00586 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HDKPDFJJ_00587 6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HDKPDFJJ_00588 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDKPDFJJ_00589 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HDKPDFJJ_00590 2.5e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HDKPDFJJ_00591 2.9e-89 ggaA M Glycosyltransferase like family 2
HDKPDFJJ_00592 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDKPDFJJ_00593 2.7e-55
HDKPDFJJ_00594 2.6e-89
HDKPDFJJ_00595 1e-132 tagG GM Transport permease protein
HDKPDFJJ_00596 1.1e-273 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDKPDFJJ_00597 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDKPDFJJ_00598 8.3e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HDKPDFJJ_00599 8.4e-101 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HDKPDFJJ_00600 2.1e-88 M Glycosyltransferase like family 2
HDKPDFJJ_00601 6.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDKPDFJJ_00602 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HDKPDFJJ_00603 1e-11
HDKPDFJJ_00604 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HDKPDFJJ_00605 7.7e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HDKPDFJJ_00606 1.9e-94 M Glycosyltransferase like family 2
HDKPDFJJ_00607 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HDKPDFJJ_00608 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDKPDFJJ_00609 2.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HDKPDFJJ_00610 9.9e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDKPDFJJ_00611 1.6e-261 tuaE M Teichuronic acid biosynthesis protein
HDKPDFJJ_00612 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
HDKPDFJJ_00613 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HDKPDFJJ_00614 1.2e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HDKPDFJJ_00615 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HDKPDFJJ_00616 6e-163 yvhJ K Transcriptional regulator
HDKPDFJJ_00617 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HDKPDFJJ_00618 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HDKPDFJJ_00619 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDKPDFJJ_00620 6.2e-154 degV S protein conserved in bacteria
HDKPDFJJ_00621 6.9e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HDKPDFJJ_00622 3.7e-45 comFB S Late competence development protein ComFB
HDKPDFJJ_00623 2.6e-80 comFC S Phosphoribosyl transferase domain
HDKPDFJJ_00624 7e-74 yvyF S flagellar protein
HDKPDFJJ_00625 8e-39 flgM KNU Negative regulator of flagellin synthesis
HDKPDFJJ_00626 4.1e-78 flgN NOU FlgN protein
HDKPDFJJ_00627 1.2e-264 flgK N flagellar hook-associated protein
HDKPDFJJ_00628 7.8e-155 flgL N Belongs to the bacterial flagellin family
HDKPDFJJ_00629 5.7e-50 yviE
HDKPDFJJ_00630 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HDKPDFJJ_00631 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HDKPDFJJ_00632 1.4e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HDKPDFJJ_00633 1.2e-55 flaG N flagellar protein FlaG
HDKPDFJJ_00634 2e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HDKPDFJJ_00635 6.5e-69 fliS N flagellar protein FliS
HDKPDFJJ_00636 1.9e-08 fliT S bacterial-type flagellum organization
HDKPDFJJ_00637 4.6e-51
HDKPDFJJ_00638 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDKPDFJJ_00639 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDKPDFJJ_00640 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDKPDFJJ_00641 3.5e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HDKPDFJJ_00642 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HDKPDFJJ_00643 2.7e-123 ftsE D cell division ATP-binding protein FtsE
HDKPDFJJ_00644 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HDKPDFJJ_00645 2.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HDKPDFJJ_00646 5.3e-56 swrA S Swarming motility protein
HDKPDFJJ_00647 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDKPDFJJ_00648 3.3e-226 yvkA EGP Major facilitator Superfamily
HDKPDFJJ_00649 1e-99 yvkB K Transcriptional regulator
HDKPDFJJ_00650 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HDKPDFJJ_00651 1.2e-30 csbA S protein conserved in bacteria
HDKPDFJJ_00652 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDKPDFJJ_00653 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDKPDFJJ_00654 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HDKPDFJJ_00655 5.7e-33 yvkN
HDKPDFJJ_00656 8e-49 yvlA
HDKPDFJJ_00657 9.2e-166 yvlB S Putative adhesin
HDKPDFJJ_00658 2.6e-26 pspB KT PspC domain
HDKPDFJJ_00659 1.2e-50 yvlD S Membrane
HDKPDFJJ_00660 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HDKPDFJJ_00661 8.9e-133 yvoA K transcriptional
HDKPDFJJ_00662 3.3e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDKPDFJJ_00663 2.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDKPDFJJ_00664 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDKPDFJJ_00665 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDKPDFJJ_00666 1.1e-159 yvoD P COG0370 Fe2 transport system protein B
HDKPDFJJ_00667 1.9e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HDKPDFJJ_00668 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HDKPDFJJ_00669 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HDKPDFJJ_00670 4.5e-140 yvpB NU protein conserved in bacteria
HDKPDFJJ_00671 2.9e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HDKPDFJJ_00672 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HDKPDFJJ_00673 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HDKPDFJJ_00674 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HDKPDFJJ_00675 2.2e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDKPDFJJ_00676 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDKPDFJJ_00677 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HDKPDFJJ_00678 2.2e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HDKPDFJJ_00679 4e-77
HDKPDFJJ_00680 0.0
HDKPDFJJ_00682 0.0 msbA2 3.6.3.44 V ABC transporter
HDKPDFJJ_00683 6.5e-276 S COG0457 FOG TPR repeat
HDKPDFJJ_00684 1.8e-97 usp CBM50 M protein conserved in bacteria
HDKPDFJJ_00685 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDKPDFJJ_00686 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HDKPDFJJ_00687 5.7e-166 rapZ S Displays ATPase and GTPase activities
HDKPDFJJ_00688 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HDKPDFJJ_00689 1.4e-170 whiA K May be required for sporulation
HDKPDFJJ_00690 1.6e-36 crh G Phosphocarrier protein Chr
HDKPDFJJ_00691 1.9e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HDKPDFJJ_00692 3.3e-32
HDKPDFJJ_00693 9.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_00694 5.8e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HDKPDFJJ_00695 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HDKPDFJJ_00696 0.0 yxdM V ABC transporter (permease)
HDKPDFJJ_00697 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDKPDFJJ_00698 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HDKPDFJJ_00699 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HDKPDFJJ_00700 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HDKPDFJJ_00701 1.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
HDKPDFJJ_00702 3.6e-174 yvdE K Transcriptional regulator
HDKPDFJJ_00703 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HDKPDFJJ_00704 1.1e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HDKPDFJJ_00705 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
HDKPDFJJ_00706 5.6e-147 malD P transport
HDKPDFJJ_00707 6.3e-157 malA S Protein of unknown function (DUF1189)
HDKPDFJJ_00708 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HDKPDFJJ_00709 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HDKPDFJJ_00710 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HDKPDFJJ_00711 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDKPDFJJ_00713 2.3e-173 S Patatin-like phospholipase
HDKPDFJJ_00714 9.8e-93 yvdQ S Protein of unknown function (DUF3231)
HDKPDFJJ_00715 4.1e-50 sugE P Small Multidrug Resistance protein
HDKPDFJJ_00716 4.3e-50 ykkC P Small Multidrug Resistance protein
HDKPDFJJ_00717 7.4e-106 yvdT K Transcriptional regulator
HDKPDFJJ_00718 2.3e-295 yveA E amino acid
HDKPDFJJ_00719 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HDKPDFJJ_00720 1.7e-273 sacB 2.4.1.10 GH68 M levansucrase activity
HDKPDFJJ_00721 9.3e-66
HDKPDFJJ_00722 6.7e-259 pbpE V Beta-lactamase
HDKPDFJJ_00723 1.7e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HDKPDFJJ_00724 5.8e-74 MA20_18690 S Protein of unknown function (DUF3237)
HDKPDFJJ_00725 1.7e-92 padC Q Phenolic acid decarboxylase
HDKPDFJJ_00726 7.5e-280 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HDKPDFJJ_00727 6.3e-76 slr K transcriptional
HDKPDFJJ_00728 4e-122 ywqC M biosynthesis protein
HDKPDFJJ_00729 3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HDKPDFJJ_00730 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HDKPDFJJ_00731 4.8e-218 epsD GT4 M Glycosyl transferase 4-like
HDKPDFJJ_00732 2.7e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDKPDFJJ_00733 1.1e-217 epsF GT4 M Glycosyl transferases group 1
HDKPDFJJ_00734 1.1e-206 epsG S EpsG family
HDKPDFJJ_00735 2.2e-193 epsH GT2 S Glycosyltransferase like family 2
HDKPDFJJ_00736 4e-206 epsI GM pyruvyl transferase
HDKPDFJJ_00737 5.6e-189 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HDKPDFJJ_00738 1.7e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDKPDFJJ_00739 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HDKPDFJJ_00740 2.4e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HDKPDFJJ_00741 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HDKPDFJJ_00742 1.7e-187 yvfF GM Exopolysaccharide biosynthesis protein
HDKPDFJJ_00743 1e-31 yvfG S YvfG protein
HDKPDFJJ_00744 1.4e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HDKPDFJJ_00745 2.6e-308 yvfH C L-lactate permease
HDKPDFJJ_00746 1e-112 yvfI K COG2186 Transcriptional regulators
HDKPDFJJ_00747 1.8e-184 lacR K Transcriptional regulator
HDKPDFJJ_00748 1.1e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
HDKPDFJJ_00749 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HDKPDFJJ_00750 7.2e-150 ganQ P transport
HDKPDFJJ_00751 0.0 lacA 3.2.1.23 G beta-galactosidase
HDKPDFJJ_00752 1.1e-250 galA 3.2.1.89 G arabinogalactan
HDKPDFJJ_00753 3.5e-198 rsbU 3.1.3.3 T response regulator
HDKPDFJJ_00754 1.8e-155 rsbQ S Alpha/beta hydrolase family
HDKPDFJJ_00755 2e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HDKPDFJJ_00756 5.8e-75 yvfS V COG0842 ABC-type multidrug transport system, permease component
HDKPDFJJ_00757 2.1e-197 desK 2.7.13.3 T Histidine kinase
HDKPDFJJ_00758 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDKPDFJJ_00759 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HDKPDFJJ_00760 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HDKPDFJJ_00761 4.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HDKPDFJJ_00762 5.4e-192 yvbX S Glycosyl hydrolase
HDKPDFJJ_00763 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HDKPDFJJ_00764 9.4e-156 yvbV EG EamA-like transporter family
HDKPDFJJ_00765 3.9e-159 yvbU K Transcriptional regulator
HDKPDFJJ_00766 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDKPDFJJ_00767 5.5e-203 araR K transcriptional
HDKPDFJJ_00768 1.6e-252 araE EGP Major facilitator Superfamily
HDKPDFJJ_00769 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HDKPDFJJ_00770 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDKPDFJJ_00771 8.5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HDKPDFJJ_00772 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDKPDFJJ_00773 2.2e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HDKPDFJJ_00774 1.6e-241 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDKPDFJJ_00775 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
HDKPDFJJ_00776 0.0 tcaA S response to antibiotic
HDKPDFJJ_00777 4e-122 exoY M Membrane
HDKPDFJJ_00778 8.6e-113 yvbH S YvbH-like oligomerisation region
HDKPDFJJ_00779 2.3e-100 yvbG U UPF0056 membrane protein
HDKPDFJJ_00780 3.5e-97 yvbF K Belongs to the GbsR family
HDKPDFJJ_00781 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HDKPDFJJ_00782 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HDKPDFJJ_00783 1.8e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDKPDFJJ_00784 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HDKPDFJJ_00785 1.9e-60 yvbF K Belongs to the GbsR family
HDKPDFJJ_00786 1.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HDKPDFJJ_00787 4.7e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HDKPDFJJ_00788 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDKPDFJJ_00789 6.7e-100 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HDKPDFJJ_00790 2e-42 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HDKPDFJJ_00791 1.9e-15 M COG3209 Rhs family protein
HDKPDFJJ_00792 6.2e-22 S Protein of unknown function (DUF2283)
HDKPDFJJ_00794 1.4e-53 yodB K transcriptional
HDKPDFJJ_00795 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
HDKPDFJJ_00796 4e-69 K transcriptional
HDKPDFJJ_00797 7.5e-36 yvzC K Transcriptional
HDKPDFJJ_00798 1.8e-152 yvaM S Serine aminopeptidase, S33
HDKPDFJJ_00799 2.4e-23 secG U Preprotein translocase subunit SecG
HDKPDFJJ_00800 5.6e-143 est 3.1.1.1 S Carboxylesterase
HDKPDFJJ_00801 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDKPDFJJ_00802 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HDKPDFJJ_00804 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_00805 1.2e-97 K Bacterial regulatory proteins, tetR family
HDKPDFJJ_00806 2.4e-54 yvaE P Small Multidrug Resistance protein
HDKPDFJJ_00807 1.3e-72 yvaD S Family of unknown function (DUF5360)
HDKPDFJJ_00808 0.0 yvaC S Fusaric acid resistance protein-like
HDKPDFJJ_00809 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDKPDFJJ_00810 9.9e-194 yvaA 1.1.1.371 S Oxidoreductase
HDKPDFJJ_00811 2.2e-48 csoR S transcriptional
HDKPDFJJ_00812 1.5e-29 copZ P Copper resistance protein CopZ
HDKPDFJJ_00813 0.0 copA 3.6.3.54 P P-type ATPase
HDKPDFJJ_00814 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HDKPDFJJ_00815 3.9e-103 bdbD O Thioredoxin
HDKPDFJJ_00816 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HDKPDFJJ_00817 1.6e-106 yvgT S membrane
HDKPDFJJ_00819 0.0 helD 3.6.4.12 L DNA helicase
HDKPDFJJ_00820 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HDKPDFJJ_00821 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HDKPDFJJ_00822 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HDKPDFJJ_00823 5.4e-86 yvgO
HDKPDFJJ_00824 2.5e-155 yvgN S reductase
HDKPDFJJ_00825 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
HDKPDFJJ_00826 4.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HDKPDFJJ_00827 3.3e-164 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HDKPDFJJ_00828 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HDKPDFJJ_00829 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HDKPDFJJ_00830 6.5e-16 S Small spore protein J (Spore_SspJ)
HDKPDFJJ_00831 4.9e-236 yvsH E Arginine ornithine antiporter
HDKPDFJJ_00832 1e-176 fhuD P ABC transporter
HDKPDFJJ_00833 7.9e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_00834 2.9e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_00835 5.4e-147 fhuC 3.6.3.34 HP ABC transporter
HDKPDFJJ_00836 2e-174 M Efflux transporter rnd family, mfp subunit
HDKPDFJJ_00837 2.1e-123 macB V ABC transporter, ATP-binding protein
HDKPDFJJ_00838 1.2e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HDKPDFJJ_00839 1.3e-64 yvrL S Regulatory protein YrvL
HDKPDFJJ_00840 3.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
HDKPDFJJ_00841 2.4e-19 S YvrJ protein family
HDKPDFJJ_00842 9.5e-98 yvrI K RNA polymerase
HDKPDFJJ_00843 7.2e-23
HDKPDFJJ_00844 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_00845 0.0 T PhoQ Sensor
HDKPDFJJ_00846 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HDKPDFJJ_00847 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_00848 3.5e-166 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HDKPDFJJ_00849 1.7e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_00850 4.9e-246 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HDKPDFJJ_00851 6.1e-100 yvqK 2.5.1.17 S Adenosyltransferase
HDKPDFJJ_00852 4.8e-227 yvqJ EGP Major facilitator Superfamily
HDKPDFJJ_00853 6.2e-61 liaI S membrane
HDKPDFJJ_00854 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HDKPDFJJ_00855 1.2e-120 liaG S Putative adhesin
HDKPDFJJ_00856 3e-125 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HDKPDFJJ_00857 7.9e-186 vraS 2.7.13.3 T Histidine kinase
HDKPDFJJ_00858 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDKPDFJJ_00859 4.1e-185 gerAC S Spore germination B3/ GerAC like, C-terminal
HDKPDFJJ_00860 1.5e-195 gerAB E Spore germination protein
HDKPDFJJ_00861 1.2e-245 gerAA EG Spore germination protein
HDKPDFJJ_00862 3.9e-24 S Protein of unknown function (DUF3970)
HDKPDFJJ_00863 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDKPDFJJ_00864 1.3e-157 yuxN K Transcriptional regulator
HDKPDFJJ_00865 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HDKPDFJJ_00866 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_00867 1.8e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDKPDFJJ_00868 2.7e-79 dps P Ferritin-like domain
HDKPDFJJ_00869 5.8e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_00870 4.2e-301 pepF2 E COG1164 Oligoendopeptidase F
HDKPDFJJ_00871 1.9e-66 S YusW-like protein
HDKPDFJJ_00872 1e-153 yusV 3.6.3.34 HP ABC transporter
HDKPDFJJ_00873 1.5e-46 yusU S Protein of unknown function (DUF2573)
HDKPDFJJ_00874 5.7e-158 yusT K LysR substrate binding domain
HDKPDFJJ_00875 5.5e-106 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_00876 2.1e-64 yusQ S Tautomerase enzyme
HDKPDFJJ_00877 1.2e-291 yusP P Major facilitator superfamily
HDKPDFJJ_00878 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
HDKPDFJJ_00879 5.4e-53 yusN M Coat F domain
HDKPDFJJ_00880 5.1e-40
HDKPDFJJ_00881 1.9e-164 fadM E Proline dehydrogenase
HDKPDFJJ_00882 8.1e-09 S YuzL-like protein
HDKPDFJJ_00883 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HDKPDFJJ_00884 1.1e-214 fadA 2.3.1.16 I Belongs to the thiolase family
HDKPDFJJ_00885 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HDKPDFJJ_00886 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HDKPDFJJ_00887 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HDKPDFJJ_00888 1.1e-39 yusG S Protein of unknown function (DUF2553)
HDKPDFJJ_00889 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HDKPDFJJ_00890 1.2e-54 traF CO Thioredoxin
HDKPDFJJ_00891 2.1e-55 yusD S SCP-2 sterol transfer family
HDKPDFJJ_00892 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDKPDFJJ_00893 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HDKPDFJJ_00894 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
HDKPDFJJ_00895 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HDKPDFJJ_00896 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HDKPDFJJ_00897 1.8e-245 sufD O assembly protein SufD
HDKPDFJJ_00898 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDKPDFJJ_00899 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HDKPDFJJ_00900 3.5e-271 sufB O FeS cluster assembly
HDKPDFJJ_00901 3.5e-64 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDKPDFJJ_00902 1e-41
HDKPDFJJ_00904 1.9e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HDKPDFJJ_00905 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HDKPDFJJ_00906 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HDKPDFJJ_00907 3.2e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HDKPDFJJ_00908 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
HDKPDFJJ_00909 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
HDKPDFJJ_00910 8.2e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HDKPDFJJ_00911 1.6e-134 yurK K UTRA
HDKPDFJJ_00912 5.9e-205 msmX P Belongs to the ABC transporter superfamily
HDKPDFJJ_00913 1e-167 bsn L Ribonuclease
HDKPDFJJ_00914 1.4e-231 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HDKPDFJJ_00915 1.2e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HDKPDFJJ_00917 3e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HDKPDFJJ_00918 3.8e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HDKPDFJJ_00919 5.2e-145 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HDKPDFJJ_00920 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HDKPDFJJ_00921 2.8e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HDKPDFJJ_00924 3.8e-57 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HDKPDFJJ_00925 3.5e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HDKPDFJJ_00926 7.4e-223 pbuX F xanthine
HDKPDFJJ_00927 5.1e-227 pbuX F Permease family
HDKPDFJJ_00928 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
HDKPDFJJ_00929 1.8e-256 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HDKPDFJJ_00930 3.1e-59 yunG
HDKPDFJJ_00931 4.8e-170 yunF S Protein of unknown function DUF72
HDKPDFJJ_00932 3.8e-140 yunE S membrane transporter protein
HDKPDFJJ_00933 1.1e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDKPDFJJ_00934 5.3e-47 yunC S Domain of unknown function (DUF1805)
HDKPDFJJ_00935 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
HDKPDFJJ_00936 1.3e-195 lytH M Peptidase, M23
HDKPDFJJ_00937 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HDKPDFJJ_00938 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDKPDFJJ_00939 9.7e-48 yutD S protein conserved in bacteria
HDKPDFJJ_00940 3.6e-73 yutE S Protein of unknown function DUF86
HDKPDFJJ_00941 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDKPDFJJ_00942 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HDKPDFJJ_00943 5.9e-199 yutH S Spore coat protein
HDKPDFJJ_00944 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
HDKPDFJJ_00945 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HDKPDFJJ_00946 1.9e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDKPDFJJ_00947 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HDKPDFJJ_00948 3.7e-57 yutI O COG0694 Thioredoxin-like proteins and domains
HDKPDFJJ_00949 1.1e-55 yuzD S protein conserved in bacteria
HDKPDFJJ_00950 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HDKPDFJJ_00951 3.2e-39 yuzB S Belongs to the UPF0349 family
HDKPDFJJ_00952 4.5e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HDKPDFJJ_00953 1.1e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDKPDFJJ_00954 3.7e-63 erpA S Belongs to the HesB IscA family
HDKPDFJJ_00955 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDKPDFJJ_00956 2.5e-115 paiB K Putative FMN-binding domain
HDKPDFJJ_00957 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDKPDFJJ_00959 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HDKPDFJJ_00960 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HDKPDFJJ_00961 8.4e-27 yuiB S Putative membrane protein
HDKPDFJJ_00962 2.1e-117 yuiC S protein conserved in bacteria
HDKPDFJJ_00963 2e-77 yuiD S protein conserved in bacteria
HDKPDFJJ_00964 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HDKPDFJJ_00965 3.9e-211 yuiF S antiporter
HDKPDFJJ_00966 1.1e-93 bioY S Biotin biosynthesis protein
HDKPDFJJ_00967 1.3e-121 yuiH S Oxidoreductase molybdopterin binding domain
HDKPDFJJ_00968 3.9e-167 besA S Putative esterase
HDKPDFJJ_00969 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_00970 5.6e-225 entC 5.4.4.2 HQ Isochorismate synthase
HDKPDFJJ_00971 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HDKPDFJJ_00972 9.3e-175 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HDKPDFJJ_00973 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDKPDFJJ_00974 1.1e-35 mbtH S MbtH-like protein
HDKPDFJJ_00975 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HDKPDFJJ_00976 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HDKPDFJJ_00977 6.1e-227 yukF QT Transcriptional regulator
HDKPDFJJ_00978 2.8e-45 esxA S Belongs to the WXG100 family
HDKPDFJJ_00979 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HDKPDFJJ_00980 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HDKPDFJJ_00981 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HDKPDFJJ_00982 0.0 esaA S type VII secretion protein EsaA
HDKPDFJJ_00983 3.3e-64 yueC S Family of unknown function (DUF5383)
HDKPDFJJ_00984 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDKPDFJJ_00985 4.8e-96 yueE S phosphohydrolase
HDKPDFJJ_00986 2.9e-24 S Protein of unknown function (DUF2642)
HDKPDFJJ_00987 1.2e-70 S Protein of unknown function (DUF2283)
HDKPDFJJ_00988 3.2e-190 yueF S transporter activity
HDKPDFJJ_00989 6.6e-31 yueG S Spore germination protein gerPA/gerPF
HDKPDFJJ_00990 1.3e-38 yueH S YueH-like protein
HDKPDFJJ_00991 5.1e-66 yueI S Protein of unknown function (DUF1694)
HDKPDFJJ_00992 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
HDKPDFJJ_00993 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDKPDFJJ_00994 5.4e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HDKPDFJJ_00995 3.8e-23 yuzC
HDKPDFJJ_00997 1.1e-149 comQ H Polyprenyl synthetase
HDKPDFJJ_00999 0.0 comP 2.7.13.3 T Histidine kinase
HDKPDFJJ_01000 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDKPDFJJ_01001 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HDKPDFJJ_01002 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HDKPDFJJ_01003 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDKPDFJJ_01004 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDKPDFJJ_01005 7.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDKPDFJJ_01006 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDKPDFJJ_01007 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HDKPDFJJ_01008 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HDKPDFJJ_01009 5e-15
HDKPDFJJ_01010 4.1e-232 maeN C COG3493 Na citrate symporter
HDKPDFJJ_01011 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HDKPDFJJ_01012 3.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HDKPDFJJ_01013 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HDKPDFJJ_01014 4.6e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HDKPDFJJ_01015 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HDKPDFJJ_01016 4.9e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HDKPDFJJ_01017 6.3e-78 yufK S Family of unknown function (DUF5366)
HDKPDFJJ_01018 5.3e-74 yuxK S protein conserved in bacteria
HDKPDFJJ_01019 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HDKPDFJJ_01020 1.9e-184 yuxJ EGP Major facilitator Superfamily
HDKPDFJJ_01022 2.3e-113 kapD L the KinA pathway to sporulation
HDKPDFJJ_01023 7.4e-70 kapB G Kinase associated protein B
HDKPDFJJ_01024 3e-232 T PhoQ Sensor
HDKPDFJJ_01025 4.4e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HDKPDFJJ_01026 1.1e-40 yugE S Domain of unknown function (DUF1871)
HDKPDFJJ_01027 2.2e-156 yugF I Hydrolase
HDKPDFJJ_01028 1.6e-85 alaR K Transcriptional regulator
HDKPDFJJ_01029 2.1e-199 yugH 2.6.1.1 E Aminotransferase
HDKPDFJJ_01030 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HDKPDFJJ_01031 1.1e-34 yuzA S Domain of unknown function (DUF378)
HDKPDFJJ_01032 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HDKPDFJJ_01033 5.3e-228 yugK C Dehydrogenase
HDKPDFJJ_01034 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HDKPDFJJ_01036 1.3e-72 yugN S YugN-like family
HDKPDFJJ_01037 1.1e-181 yugO P COG1226 Kef-type K transport systems
HDKPDFJJ_01038 1.1e-53 mstX S Membrane-integrating protein Mistic
HDKPDFJJ_01039 2.3e-38
HDKPDFJJ_01040 1.4e-116 yugP S Zn-dependent protease
HDKPDFJJ_01041 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HDKPDFJJ_01042 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HDKPDFJJ_01043 3.1e-71 yugU S Uncharacterised protein family UPF0047
HDKPDFJJ_01044 1e-35
HDKPDFJJ_01045 3.8e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HDKPDFJJ_01046 1.3e-223 mcpA NT chemotaxis protein
HDKPDFJJ_01047 1.1e-220 mcpA NT chemotaxis protein
HDKPDFJJ_01048 3.2e-294 mcpA NT chemotaxis protein
HDKPDFJJ_01049 7.3e-238 mcpA NT chemotaxis protein
HDKPDFJJ_01050 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HDKPDFJJ_01051 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HDKPDFJJ_01052 2.7e-274 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HDKPDFJJ_01053 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HDKPDFJJ_01054 1.1e-250 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HDKPDFJJ_01055 3.7e-182 ygjR S Oxidoreductase
HDKPDFJJ_01056 3.7e-189 yubA S transporter activity
HDKPDFJJ_01057 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HDKPDFJJ_01059 2.2e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HDKPDFJJ_01060 7.5e-275 yubD P Major Facilitator Superfamily
HDKPDFJJ_01061 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDKPDFJJ_01062 1e-38 yiaA S yiaA/B two helix domain
HDKPDFJJ_01063 1.3e-235 ktrB P Potassium
HDKPDFJJ_01064 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HDKPDFJJ_01065 2.2e-91 yuaB
HDKPDFJJ_01066 1.9e-92 yuaC K Belongs to the GbsR family
HDKPDFJJ_01067 5.2e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HDKPDFJJ_01068 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HDKPDFJJ_01069 7.4e-106 yuaD
HDKPDFJJ_01070 3.9e-84 yuaE S DinB superfamily
HDKPDFJJ_01071 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HDKPDFJJ_01072 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HDKPDFJJ_01073 2.4e-92 M1-753 M FR47-like protein
HDKPDFJJ_01074 1.3e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
HDKPDFJJ_01077 2e-08
HDKPDFJJ_01084 1.3e-09
HDKPDFJJ_01085 7.8e-08
HDKPDFJJ_01094 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDKPDFJJ_01095 8.9e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HDKPDFJJ_01096 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HDKPDFJJ_01097 1.1e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HDKPDFJJ_01098 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDKPDFJJ_01099 1.4e-75 tspO T membrane
HDKPDFJJ_01100 3.1e-203 cotI S Spore coat protein
HDKPDFJJ_01101 3.1e-217 cotSA M Glycosyl transferases group 1
HDKPDFJJ_01102 5.1e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
HDKPDFJJ_01104 1.8e-231 ytcC M Glycosyltransferase Family 4
HDKPDFJJ_01105 1.7e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HDKPDFJJ_01106 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDKPDFJJ_01107 4.3e-152 galU 2.7.7.9 M Nucleotidyl transferase
HDKPDFJJ_01108 2.6e-132 dksA T COG1734 DnaK suppressor protein
HDKPDFJJ_01109 2.7e-271 menF 5.4.4.2 HQ Isochorismate synthase
HDKPDFJJ_01110 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HDKPDFJJ_01111 1e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HDKPDFJJ_01112 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HDKPDFJJ_01113 1e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HDKPDFJJ_01114 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HDKPDFJJ_01115 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
HDKPDFJJ_01116 7.3e-138 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HDKPDFJJ_01117 1.1e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HDKPDFJJ_01118 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HDKPDFJJ_01119 1.1e-24 S Domain of Unknown Function (DUF1540)
HDKPDFJJ_01120 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HDKPDFJJ_01121 4e-248 cydA 1.10.3.14 C oxidase, subunit
HDKPDFJJ_01122 6.1e-41 rpmE2 J Ribosomal protein L31
HDKPDFJJ_01123 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HDKPDFJJ_01124 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDKPDFJJ_01125 2.4e-72 ytkA S YtkA-like
HDKPDFJJ_01127 2.1e-76 dps P Belongs to the Dps family
HDKPDFJJ_01128 7.8e-62 ytkC S Bacteriophage holin family
HDKPDFJJ_01129 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HDKPDFJJ_01130 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HDKPDFJJ_01131 1.4e-144 ytlC P ABC transporter
HDKPDFJJ_01132 8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HDKPDFJJ_01133 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HDKPDFJJ_01134 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HDKPDFJJ_01135 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HDKPDFJJ_01136 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDKPDFJJ_01137 0.0 asnB 6.3.5.4 E Asparagine synthase
HDKPDFJJ_01138 2.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HDKPDFJJ_01139 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HDKPDFJJ_01140 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HDKPDFJJ_01141 2.8e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HDKPDFJJ_01142 9.7e-106 ytqB J Putative rRNA methylase
HDKPDFJJ_01143 8.1e-190 yhcC S Fe-S oxidoreductase
HDKPDFJJ_01144 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HDKPDFJJ_01146 5.1e-66 ytrA K GntR family transcriptional regulator
HDKPDFJJ_01147 2.1e-160 ytrB P abc transporter atp-binding protein
HDKPDFJJ_01148 6.1e-153 P ABC-2 family transporter protein
HDKPDFJJ_01149 2.6e-148
HDKPDFJJ_01150 9.1e-127 ytrE V ABC transporter, ATP-binding protein
HDKPDFJJ_01151 2.3e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HDKPDFJJ_01152 1.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_01153 1.2e-185 T PhoQ Sensor
HDKPDFJJ_01154 7.3e-138 bceA V ABC transporter, ATP-binding protein
HDKPDFJJ_01155 0.0 bceB V ABC transporter (permease)
HDKPDFJJ_01156 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HDKPDFJJ_01157 3.9e-210 yttB EGP Major facilitator Superfamily
HDKPDFJJ_01158 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HDKPDFJJ_01159 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HDKPDFJJ_01160 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDKPDFJJ_01161 2.1e-51 ytwF P Sulfurtransferase
HDKPDFJJ_01162 2.2e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HDKPDFJJ_01163 4.4e-144 amyC P ABC transporter (permease)
HDKPDFJJ_01164 6.2e-168 amyD P ABC transporter
HDKPDFJJ_01165 3.7e-243 msmE G Bacterial extracellular solute-binding protein
HDKPDFJJ_01166 5.6e-189 msmR K Transcriptional regulator
HDKPDFJJ_01167 1.1e-172 ytaP S Acetyl xylan esterase (AXE1)
HDKPDFJJ_01168 1.5e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HDKPDFJJ_01169 2.7e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HDKPDFJJ_01170 4.5e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HDKPDFJJ_01171 1.7e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HDKPDFJJ_01172 1.2e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HDKPDFJJ_01173 8.3e-221 bioI 1.14.14.46 C Cytochrome P450
HDKPDFJJ_01174 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HDKPDFJJ_01175 2e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HDKPDFJJ_01176 8.9e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HDKPDFJJ_01177 0.0 ytdP K Transcriptional regulator
HDKPDFJJ_01178 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HDKPDFJJ_01179 5.2e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HDKPDFJJ_01180 6.2e-70 yteS G transport
HDKPDFJJ_01181 1.3e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HDKPDFJJ_01182 5.3e-116 yteU S Integral membrane protein
HDKPDFJJ_01183 3.1e-26 yteV S Sporulation protein Cse60
HDKPDFJJ_01184 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HDKPDFJJ_01185 2e-230 ytfP S HI0933-like protein
HDKPDFJJ_01186 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDKPDFJJ_01187 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDKPDFJJ_01188 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HDKPDFJJ_01189 1.3e-131 ythP V ABC transporter
HDKPDFJJ_01190 3.8e-202 ythQ U Bacterial ABC transporter protein EcsB
HDKPDFJJ_01191 7.2e-226 pbuO S permease
HDKPDFJJ_01192 1.5e-269 pepV 3.5.1.18 E Dipeptidase
HDKPDFJJ_01193 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDKPDFJJ_01194 1.2e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HDKPDFJJ_01195 3.8e-165 ytlQ
HDKPDFJJ_01196 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HDKPDFJJ_01197 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HDKPDFJJ_01198 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HDKPDFJJ_01199 2e-45 ytzH S YtzH-like protein
HDKPDFJJ_01200 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDKPDFJJ_01201 2.4e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HDKPDFJJ_01202 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HDKPDFJJ_01203 2.2e-51 ytzB S small secreted protein
HDKPDFJJ_01204 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HDKPDFJJ_01205 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HDKPDFJJ_01206 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDKPDFJJ_01207 9.8e-149 ytpQ S Belongs to the UPF0354 family
HDKPDFJJ_01208 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDKPDFJJ_01209 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HDKPDFJJ_01210 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HDKPDFJJ_01211 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDKPDFJJ_01212 6.6e-17 ytxH S COG4980 Gas vesicle protein
HDKPDFJJ_01213 1.1e-53 ytxJ O Protein of unknown function (DUF2847)
HDKPDFJJ_01214 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HDKPDFJJ_01215 1.7e-182 ccpA K catabolite control protein A
HDKPDFJJ_01216 7.9e-146 motA N flagellar motor
HDKPDFJJ_01217 1.4e-125 motS N Flagellar motor protein
HDKPDFJJ_01218 6.1e-224 acuC BQ histone deacetylase
HDKPDFJJ_01219 7.9e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HDKPDFJJ_01220 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HDKPDFJJ_01221 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HDKPDFJJ_01222 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDKPDFJJ_01224 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDKPDFJJ_01225 8.2e-310 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HDKPDFJJ_01226 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HDKPDFJJ_01227 1e-108 yttP K Transcriptional regulator
HDKPDFJJ_01228 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HDKPDFJJ_01229 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDKPDFJJ_01230 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HDKPDFJJ_01231 3.5e-208 iscS2 2.8.1.7 E Cysteine desulfurase
HDKPDFJJ_01232 6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDKPDFJJ_01233 2e-29 sspB S spore protein
HDKPDFJJ_01234 2.3e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HDKPDFJJ_01235 0.0 ytcJ S amidohydrolase
HDKPDFJJ_01236 1.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDKPDFJJ_01237 1.8e-179 sppA OU signal peptide peptidase SppA
HDKPDFJJ_01238 8.5e-87 yteJ S RDD family
HDKPDFJJ_01239 5.6e-116 ytfI S Protein of unknown function (DUF2953)
HDKPDFJJ_01240 8.7e-70 ytfJ S Sporulation protein YtfJ
HDKPDFJJ_01241 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDKPDFJJ_01242 2.7e-164 ytxK 2.1.1.72 L DNA methylase
HDKPDFJJ_01243 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDKPDFJJ_01244 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HDKPDFJJ_01245 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDKPDFJJ_01246 1.2e-266 argH 4.3.2.1 E argininosuccinate lyase
HDKPDFJJ_01248 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDKPDFJJ_01249 1.7e-130 ytkL S Belongs to the UPF0173 family
HDKPDFJJ_01250 1.9e-172 ytlI K LysR substrate binding domain
HDKPDFJJ_01251 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
HDKPDFJJ_01252 1.8e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
HDKPDFJJ_01253 6.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
HDKPDFJJ_01254 1.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
HDKPDFJJ_01255 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
HDKPDFJJ_01256 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HDKPDFJJ_01257 4.4e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDKPDFJJ_01258 7.1e-46 ytnI O COG0695 Glutaredoxin and related proteins
HDKPDFJJ_01259 2.6e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDKPDFJJ_01260 2e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HDKPDFJJ_01261 3e-237 ytnL 3.5.1.47 E hydrolase activity
HDKPDFJJ_01262 2.7e-155 ytnM S membrane transporter protein
HDKPDFJJ_01263 3e-240 ytoI K transcriptional regulator containing CBS domains
HDKPDFJJ_01264 2.4e-47 ytpI S YtpI-like protein
HDKPDFJJ_01265 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HDKPDFJJ_01266 9.2e-29
HDKPDFJJ_01267 8.2e-69 ytrI
HDKPDFJJ_01268 3.2e-56 ytrH S Sporulation protein YtrH
HDKPDFJJ_01269 0.0 dnaE 2.7.7.7 L DNA polymerase
HDKPDFJJ_01270 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HDKPDFJJ_01271 2.4e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDKPDFJJ_01272 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HDKPDFJJ_01273 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDKPDFJJ_01274 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HDKPDFJJ_01275 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HDKPDFJJ_01276 2.6e-192 ytvI S sporulation integral membrane protein YtvI
HDKPDFJJ_01277 4.7e-71 yeaL S membrane
HDKPDFJJ_01278 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HDKPDFJJ_01279 4.1e-242 icd 1.1.1.42 C isocitrate
HDKPDFJJ_01280 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HDKPDFJJ_01281 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_01282 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HDKPDFJJ_01283 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDKPDFJJ_01284 3.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDKPDFJJ_01285 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HDKPDFJJ_01286 1.3e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDKPDFJJ_01287 8.9e-161 ytbE S reductase
HDKPDFJJ_01288 4.6e-203 ytbD EGP Major facilitator Superfamily
HDKPDFJJ_01289 4.9e-66 ytcD K Transcriptional regulator
HDKPDFJJ_01290 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDKPDFJJ_01291 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HDKPDFJJ_01292 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDKPDFJJ_01293 2.2e-265 dnaB L Membrane attachment protein
HDKPDFJJ_01294 2.5e-172 dnaI L Primosomal protein DnaI
HDKPDFJJ_01295 1.1e-107 ytxB S SNARE associated Golgi protein
HDKPDFJJ_01296 1.6e-157 ytxC S YtxC-like family
HDKPDFJJ_01298 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDKPDFJJ_01299 7.3e-149 ysaA S HAD-hyrolase-like
HDKPDFJJ_01300 0.0 lytS 2.7.13.3 T Histidine kinase
HDKPDFJJ_01301 7e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HDKPDFJJ_01302 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HDKPDFJJ_01303 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HDKPDFJJ_01305 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDKPDFJJ_01306 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HDKPDFJJ_01307 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDKPDFJJ_01308 7.5e-45 ysdA S Membrane
HDKPDFJJ_01309 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HDKPDFJJ_01310 3.8e-204 ysdC G COG1363 Cellulase M and related proteins
HDKPDFJJ_01311 8.9e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HDKPDFJJ_01312 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HDKPDFJJ_01313 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HDKPDFJJ_01314 2.4e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HDKPDFJJ_01315 2.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HDKPDFJJ_01316 5.2e-223 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HDKPDFJJ_01317 4.9e-251 araN G carbohydrate transport
HDKPDFJJ_01318 1.4e-167 araP G carbohydrate transport
HDKPDFJJ_01319 3.8e-143 araQ G transport system permease
HDKPDFJJ_01320 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HDKPDFJJ_01321 0.0 cstA T Carbon starvation protein
HDKPDFJJ_01322 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
HDKPDFJJ_01323 1.5e-255 glcF C Glycolate oxidase
HDKPDFJJ_01324 2.4e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
HDKPDFJJ_01325 6.6e-204 ysfB KT regulator
HDKPDFJJ_01326 5.8e-32 sspI S Belongs to the SspI family
HDKPDFJJ_01327 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDKPDFJJ_01328 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDKPDFJJ_01329 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDKPDFJJ_01330 2.6e-169 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDKPDFJJ_01331 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDKPDFJJ_01332 1.7e-85 cvpA S membrane protein, required for colicin V production
HDKPDFJJ_01333 0.0 polX L COG1796 DNA polymerase IV (family X)
HDKPDFJJ_01334 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDKPDFJJ_01335 7.3e-68 yshE S membrane
HDKPDFJJ_01336 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HDKPDFJJ_01337 1.1e-98 fadR K Transcriptional regulator
HDKPDFJJ_01338 1.6e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HDKPDFJJ_01339 4.5e-135 etfB C Electron transfer flavoprotein
HDKPDFJJ_01340 1.5e-175 etfA C Electron transfer flavoprotein
HDKPDFJJ_01342 3.5e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HDKPDFJJ_01343 2e-52 trxA O Belongs to the thioredoxin family
HDKPDFJJ_01344 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDKPDFJJ_01345 1.8e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HDKPDFJJ_01346 1.2e-79 yslB S Protein of unknown function (DUF2507)
HDKPDFJJ_01347 2.4e-107 sdhC C succinate dehydrogenase
HDKPDFJJ_01348 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HDKPDFJJ_01349 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HDKPDFJJ_01350 5.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HDKPDFJJ_01351 3.3e-30 gerE K Transcriptional regulator
HDKPDFJJ_01352 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HDKPDFJJ_01353 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDKPDFJJ_01354 5e-196 gerM S COG5401 Spore germination protein
HDKPDFJJ_01355 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HDKPDFJJ_01356 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDKPDFJJ_01357 1.5e-91 ysnB S Phosphoesterase
HDKPDFJJ_01359 1.2e-130 ysnF S protein conserved in bacteria
HDKPDFJJ_01360 3.2e-109 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HDKPDFJJ_01361 6.2e-76 ysnE K acetyltransferase
HDKPDFJJ_01363 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HDKPDFJJ_01364 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HDKPDFJJ_01365 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HDKPDFJJ_01366 7.9e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HDKPDFJJ_01367 2.2e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HDKPDFJJ_01368 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDKPDFJJ_01369 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDKPDFJJ_01370 1.9e-186 ysoA H Tetratricopeptide repeat
HDKPDFJJ_01371 1.6e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDKPDFJJ_01372 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDKPDFJJ_01373 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HDKPDFJJ_01374 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HDKPDFJJ_01375 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HDKPDFJJ_01376 1.4e-89 ysxD
HDKPDFJJ_01377 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HDKPDFJJ_01378 3.6e-146 hemX O cytochrome C
HDKPDFJJ_01379 3.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HDKPDFJJ_01380 8.4e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HDKPDFJJ_01381 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HDKPDFJJ_01382 5.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HDKPDFJJ_01383 6.2e-201 spoVID M stage VI sporulation protein D
HDKPDFJJ_01384 2.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HDKPDFJJ_01385 1.6e-25
HDKPDFJJ_01386 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDKPDFJJ_01387 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDKPDFJJ_01388 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HDKPDFJJ_01389 7.3e-162 spoIIB S Sporulation related domain
HDKPDFJJ_01390 8.3e-102 maf D septum formation protein Maf
HDKPDFJJ_01391 1.3e-125 radC E Belongs to the UPF0758 family
HDKPDFJJ_01392 1.8e-184 mreB D Rod shape-determining protein MreB
HDKPDFJJ_01393 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HDKPDFJJ_01394 1.4e-84 mreD M shape-determining protein
HDKPDFJJ_01395 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HDKPDFJJ_01396 2.5e-144 minD D Belongs to the ParA family
HDKPDFJJ_01397 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HDKPDFJJ_01398 5.9e-160 spoIVFB S Stage IV sporulation protein
HDKPDFJJ_01399 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HDKPDFJJ_01400 1.2e-55 ysxB J ribosomal protein
HDKPDFJJ_01401 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HDKPDFJJ_01402 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HDKPDFJJ_01403 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDKPDFJJ_01404 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HDKPDFJJ_01405 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
HDKPDFJJ_01406 3.9e-93 niaR S small molecule binding protein (contains 3H domain)
HDKPDFJJ_01407 1.8e-228 nifS 2.8.1.7 E Cysteine desulfurase
HDKPDFJJ_01408 4.1e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HDKPDFJJ_01409 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HDKPDFJJ_01410 5.4e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HDKPDFJJ_01411 4.8e-157 safA M spore coat assembly protein SafA
HDKPDFJJ_01412 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDKPDFJJ_01413 3.6e-126 yebC K transcriptional regulatory protein
HDKPDFJJ_01414 2.2e-260 alsT E Sodium alanine symporter
HDKPDFJJ_01415 8.9e-51 S Family of unknown function (DUF5412)
HDKPDFJJ_01417 7.2e-118 yrzF T serine threonine protein kinase
HDKPDFJJ_01418 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HDKPDFJJ_01419 1.7e-251 csbX EGP Major facilitator Superfamily
HDKPDFJJ_01420 4.8e-93 bofC S BofC C-terminal domain
HDKPDFJJ_01421 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDKPDFJJ_01422 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDKPDFJJ_01423 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HDKPDFJJ_01424 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDKPDFJJ_01425 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDKPDFJJ_01426 8e-39 yajC U Preprotein translocase subunit YajC
HDKPDFJJ_01427 1.2e-74 yrzE S Protein of unknown function (DUF3792)
HDKPDFJJ_01428 9.2e-113 yrbG S membrane
HDKPDFJJ_01429 8.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDKPDFJJ_01430 1.6e-48 yrzD S Post-transcriptional regulator
HDKPDFJJ_01431 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HDKPDFJJ_01432 1.9e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HDKPDFJJ_01433 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HDKPDFJJ_01434 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HDKPDFJJ_01435 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDKPDFJJ_01436 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDKPDFJJ_01437 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDKPDFJJ_01438 2.9e-258 lytH 3.5.1.28 M COG3103 SH3 domain protein
HDKPDFJJ_01440 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HDKPDFJJ_01441 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HDKPDFJJ_01442 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HDKPDFJJ_01443 9.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HDKPDFJJ_01444 1.2e-70 cymR K Transcriptional regulator
HDKPDFJJ_01445 4.4e-211 iscS 2.8.1.7 E Cysteine desulfurase
HDKPDFJJ_01446 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDKPDFJJ_01447 1.4e-15 S COG0457 FOG TPR repeat
HDKPDFJJ_01448 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDKPDFJJ_01449 6.6e-81 yrrD S protein conserved in bacteria
HDKPDFJJ_01450 9.8e-31 yrzR
HDKPDFJJ_01451 8e-08 S Protein of unknown function (DUF3918)
HDKPDFJJ_01452 7.6e-107 glnP P ABC transporter
HDKPDFJJ_01453 1.8e-108 gluC P ABC transporter
HDKPDFJJ_01454 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
HDKPDFJJ_01455 1.2e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HDKPDFJJ_01456 2.7e-170 yrrI S AI-2E family transporter
HDKPDFJJ_01457 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDKPDFJJ_01458 1.7e-41 yrzL S Belongs to the UPF0297 family
HDKPDFJJ_01459 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDKPDFJJ_01460 1.2e-45 yrzB S Belongs to the UPF0473 family
HDKPDFJJ_01461 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDKPDFJJ_01462 8.6e-119 yrrM 2.1.1.104 S O-methyltransferase
HDKPDFJJ_01463 4.3e-172 yegQ O Peptidase U32
HDKPDFJJ_01464 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HDKPDFJJ_01465 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HDKPDFJJ_01466 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDKPDFJJ_01467 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HDKPDFJJ_01468 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HDKPDFJJ_01469 1e-25 yrzA S Protein of unknown function (DUF2536)
HDKPDFJJ_01470 1.9e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HDKPDFJJ_01471 1.2e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDKPDFJJ_01472 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HDKPDFJJ_01473 5.9e-208 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HDKPDFJJ_01474 4.6e-35 yrhC S YrhC-like protein
HDKPDFJJ_01475 5.4e-78 yrhD S Protein of unknown function (DUF1641)
HDKPDFJJ_01476 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HDKPDFJJ_01477 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HDKPDFJJ_01478 3e-142 focA P Formate nitrite
HDKPDFJJ_01481 1.1e-95 yrhH Q methyltransferase
HDKPDFJJ_01482 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HDKPDFJJ_01483 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HDKPDFJJ_01484 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
HDKPDFJJ_01485 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
HDKPDFJJ_01486 9.4e-117 S ATPases associated with a variety of cellular activities
HDKPDFJJ_01487 5.7e-64 S ABC-2 family transporter protein
HDKPDFJJ_01488 8.3e-63 S ABC-2 family transporter protein
HDKPDFJJ_01489 7.2e-104 Q TIGRFAM amino acid adenylation domain
HDKPDFJJ_01490 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HDKPDFJJ_01491 6.6e-181 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
HDKPDFJJ_01492 2.6e-100 EF ATP-grasp domain
HDKPDFJJ_01493 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
HDKPDFJJ_01494 1.5e-52 S dehydrogenases and related proteins
HDKPDFJJ_01495 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
HDKPDFJJ_01496 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
HDKPDFJJ_01497 3.2e-17 yrhK S YrhK-like protein
HDKPDFJJ_01498 0.0 yrhL I Acyltransferase family
HDKPDFJJ_01499 1e-148 rsiV S Protein of unknown function (DUF3298)
HDKPDFJJ_01500 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HDKPDFJJ_01501 7e-150 yrhO K Archaeal transcriptional regulator TrmB
HDKPDFJJ_01502 1.1e-105 yrhP E LysE type translocator
HDKPDFJJ_01503 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HDKPDFJJ_01504 0.0 levR K PTS system fructose IIA component
HDKPDFJJ_01505 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
HDKPDFJJ_01506 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HDKPDFJJ_01507 2.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HDKPDFJJ_01508 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HDKPDFJJ_01509 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HDKPDFJJ_01510 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HDKPDFJJ_01511 2.1e-196 adhA 1.1.1.1 C alcohol dehydrogenase
HDKPDFJJ_01512 1.6e-25 yphJ 4.1.1.44 S peroxiredoxin activity
HDKPDFJJ_01513 4.3e-47 yraB K helix_turn_helix, mercury resistance
HDKPDFJJ_01514 1.1e-47 yraD M Spore coat protein
HDKPDFJJ_01515 7.5e-26 yraE
HDKPDFJJ_01516 5.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HDKPDFJJ_01517 6.4e-63 yraF M Spore coat protein
HDKPDFJJ_01518 3.4e-36 yraG
HDKPDFJJ_01519 2.1e-64 E Glyoxalase-like domain
HDKPDFJJ_01520 5.4e-61 T sh3 domain protein
HDKPDFJJ_01521 2.2e-60 T sh3 domain protein
HDKPDFJJ_01522 1.1e-150 S Alpha beta hydrolase
HDKPDFJJ_01523 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDKPDFJJ_01524 8.5e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HDKPDFJJ_01525 1.9e-186 yrpG C Aldo/keto reductase family
HDKPDFJJ_01526 3.3e-92 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HDKPDFJJ_01527 1.5e-114 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HDKPDFJJ_01528 6.4e-26 epsA I Passenger-associated-transport-repeat
HDKPDFJJ_01529 8.1e-49 yjbR S YjbR
HDKPDFJJ_01530 6.1e-117 bmrR K helix_turn_helix, mercury resistance
HDKPDFJJ_01531 1.9e-98 flr S Flavin reductase like domain
HDKPDFJJ_01532 8.1e-123 yrpD S Domain of unknown function, YrpD
HDKPDFJJ_01533 3.8e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDKPDFJJ_01534 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HDKPDFJJ_01535 4.2e-166 aadK G Streptomycin adenylyltransferase
HDKPDFJJ_01536 1.9e-89 yrdA S DinB family
HDKPDFJJ_01538 1.8e-55 S Protein of unknown function (DUF2568)
HDKPDFJJ_01539 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
HDKPDFJJ_01540 5.5e-74 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
HDKPDFJJ_01541 4.6e-148 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
HDKPDFJJ_01542 4.4e-251 cscA 3.2.1.26 GH32 G invertase
HDKPDFJJ_01543 2.7e-198 rafB P LacY proton/sugar symporter
HDKPDFJJ_01544 1.1e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
HDKPDFJJ_01545 3.9e-149 msmF P Binding-protein-dependent transport system inner membrane component
HDKPDFJJ_01546 6.9e-229 msmE G Bacterial extracellular solute-binding protein
HDKPDFJJ_01547 1.2e-164 scrR K transcriptional
HDKPDFJJ_01548 7.9e-65 K Transcriptional regulator
HDKPDFJJ_01549 3.2e-39 K Acetyltransferase (GNAT) family
HDKPDFJJ_01550 1.6e-222 cypA C Cytochrome P450
HDKPDFJJ_01551 6.5e-44 yrdF K ribonuclease inhibitor
HDKPDFJJ_01552 6.3e-79 bkdR K helix_turn_helix ASNC type
HDKPDFJJ_01553 1.6e-137 azlC E AzlC protein
HDKPDFJJ_01554 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HDKPDFJJ_01555 2.3e-227 brnQ E Component of the transport system for branched-chain amino acids
HDKPDFJJ_01556 1.9e-16 yodA S tautomerase
HDKPDFJJ_01557 5.1e-157 czcD P COG1230 Co Zn Cd efflux system component
HDKPDFJJ_01558 8.6e-198 trkA P Oxidoreductase
HDKPDFJJ_01559 3.3e-158 yrdQ K Transcriptional regulator
HDKPDFJJ_01560 4.1e-170 yrdR EG EamA-like transporter family
HDKPDFJJ_01561 3.9e-16 S YrzO-like protein
HDKPDFJJ_01562 1.2e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HDKPDFJJ_01563 3.4e-82 bltD 2.3.1.57 K FR47-like protein
HDKPDFJJ_01564 8.7e-210 blt EGP Major facilitator Superfamily
HDKPDFJJ_01565 3.2e-147 bltR K helix_turn_helix, mercury resistance
HDKPDFJJ_01567 4.9e-107 yrkC G Cupin domain
HDKPDFJJ_01568 5e-21
HDKPDFJJ_01569 7.8e-39 yrkD S protein conserved in bacteria
HDKPDFJJ_01570 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
HDKPDFJJ_01571 1.2e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
HDKPDFJJ_01572 2.7e-205 yrkH P Rhodanese Homology Domain
HDKPDFJJ_01573 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HDKPDFJJ_01574 5.4e-112 yrkJ S membrane transporter protein
HDKPDFJJ_01575 1.9e-111 K COG1802 Transcriptional regulators
HDKPDFJJ_01576 5.9e-180 yjlA EG Putative multidrug resistance efflux transporter
HDKPDFJJ_01577 3e-90 K Transcriptional regulator PadR-like family
HDKPDFJJ_01578 9.2e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HDKPDFJJ_01581 2.6e-71 rusA L Endodeoxyribonuclease RusA
HDKPDFJJ_01582 6.8e-30 yqaO S Phage-like element PBSX protein XtrA
HDKPDFJJ_01583 9.7e-66 S Psort location Cytoplasmic, score
HDKPDFJJ_01584 4.7e-125 S Beta protein
HDKPDFJJ_01585 2.7e-31
HDKPDFJJ_01586 6.9e-75 L Transposase
HDKPDFJJ_01587 1.9e-95
HDKPDFJJ_01588 1.7e-76 yqaS L DNA packaging
HDKPDFJJ_01589 3.1e-26 S phage terminase, large subunit
HDKPDFJJ_01591 2e-102 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HDKPDFJJ_01593 1.4e-40
HDKPDFJJ_01594 2.8e-47
HDKPDFJJ_01595 8.5e-30 S SMI1 / KNR4 family
HDKPDFJJ_01596 1.1e-26 yokK S SMI1 / KNR4 family
HDKPDFJJ_01597 2.8e-225 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HDKPDFJJ_01598 2e-90 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_01599 9.1e-29 S Agrobacterium tumefaciens protein Atu4866
HDKPDFJJ_01600 1.1e-90 lacR K Transcriptional regulator
HDKPDFJJ_01601 1e-70 K MerR family transcriptional regulator
HDKPDFJJ_01602 3.3e-139 yvgN 1.1.1.346 S Reductase
HDKPDFJJ_01603 4.1e-193 S Aspartate phosphatase response regulator
HDKPDFJJ_01605 1e-66 K Glyoxalase bleomycin resistance protein dioxygenase
HDKPDFJJ_01606 5e-154 K Transcriptional regulator
HDKPDFJJ_01607 5.8e-258 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDKPDFJJ_01608 2.9e-31 cisA2 L Recombinase
HDKPDFJJ_01609 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDKPDFJJ_01610 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HDKPDFJJ_01611 5.7e-132 yqeB
HDKPDFJJ_01612 3e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HDKPDFJJ_01613 1.2e-104 yqeD S SNARE associated Golgi protein
HDKPDFJJ_01614 1.3e-134 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HDKPDFJJ_01615 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HDKPDFJJ_01617 5.3e-95 yqeG S hydrolase of the HAD superfamily
HDKPDFJJ_01618 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HDKPDFJJ_01619 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDKPDFJJ_01620 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HDKPDFJJ_01621 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDKPDFJJ_01622 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HDKPDFJJ_01623 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDKPDFJJ_01624 9.4e-138 yqeM Q Methyltransferase
HDKPDFJJ_01625 2.1e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDKPDFJJ_01626 6.2e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HDKPDFJJ_01627 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HDKPDFJJ_01628 0.0 comEC S Competence protein ComEC
HDKPDFJJ_01629 4.1e-15 S YqzM-like protein
HDKPDFJJ_01630 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HDKPDFJJ_01631 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HDKPDFJJ_01632 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HDKPDFJJ_01633 1.5e-222 spoIIP M stage II sporulation protein P
HDKPDFJJ_01634 4.7e-52 yqxA S Protein of unknown function (DUF3679)
HDKPDFJJ_01635 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDKPDFJJ_01636 3.5e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
HDKPDFJJ_01637 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDKPDFJJ_01638 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDKPDFJJ_01639 0.0 dnaK O Heat shock 70 kDa protein
HDKPDFJJ_01640 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDKPDFJJ_01641 5.4e-175 prmA J Methylates ribosomal protein L11
HDKPDFJJ_01642 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDKPDFJJ_01643 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HDKPDFJJ_01644 2.3e-157 yqeW P COG1283 Na phosphate symporter
HDKPDFJJ_01645 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HDKPDFJJ_01646 2.5e-61 yqeY S Yqey-like protein
HDKPDFJJ_01647 7.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HDKPDFJJ_01648 3.7e-121 yqfA S UPF0365 protein
HDKPDFJJ_01649 1.5e-23 yqfB
HDKPDFJJ_01650 2.7e-45 yqfC S sporulation protein YqfC
HDKPDFJJ_01651 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HDKPDFJJ_01652 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HDKPDFJJ_01654 0.0 yqfF S membrane-associated HD superfamily hydrolase
HDKPDFJJ_01655 6.7e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDKPDFJJ_01656 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HDKPDFJJ_01657 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HDKPDFJJ_01658 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDKPDFJJ_01659 8.4e-19 S YqzL-like protein
HDKPDFJJ_01660 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
HDKPDFJJ_01661 5.7e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HDKPDFJJ_01662 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HDKPDFJJ_01663 4.5e-112 ccpN K CBS domain
HDKPDFJJ_01664 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDKPDFJJ_01665 1.7e-87 yaiI S Belongs to the UPF0178 family
HDKPDFJJ_01666 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDKPDFJJ_01667 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDKPDFJJ_01668 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HDKPDFJJ_01669 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
HDKPDFJJ_01670 2.8e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDKPDFJJ_01671 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HDKPDFJJ_01672 7e-08 yqfQ S YqfQ-like protein
HDKPDFJJ_01673 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDKPDFJJ_01674 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HDKPDFJJ_01675 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HDKPDFJJ_01676 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HDKPDFJJ_01677 4.2e-77 zur P Belongs to the Fur family
HDKPDFJJ_01678 1e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HDKPDFJJ_01679 4.3e-62 yqfX S membrane
HDKPDFJJ_01680 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HDKPDFJJ_01681 5.2e-47 yqfZ M LysM domain
HDKPDFJJ_01682 3.9e-131 yqgB S Protein of unknown function (DUF1189)
HDKPDFJJ_01683 4e-73 yqgC S protein conserved in bacteria
HDKPDFJJ_01684 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HDKPDFJJ_01685 2.5e-231 yqgE EGP Major facilitator superfamily
HDKPDFJJ_01686 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HDKPDFJJ_01687 9e-143 pstS P Phosphate
HDKPDFJJ_01688 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HDKPDFJJ_01689 1.3e-157 pstA P Phosphate transport system permease
HDKPDFJJ_01690 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDKPDFJJ_01691 1.9e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDKPDFJJ_01692 7e-75 yqzC S YceG-like family
HDKPDFJJ_01693 2.1e-50 yqzD
HDKPDFJJ_01695 1.6e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HDKPDFJJ_01696 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDKPDFJJ_01697 1.1e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDKPDFJJ_01698 2.5e-09 yqgO
HDKPDFJJ_01699 2e-264 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HDKPDFJJ_01700 3.1e-33 yqgQ S Protein conserved in bacteria
HDKPDFJJ_01701 5.2e-181 glcK 2.7.1.2 G Glucokinase
HDKPDFJJ_01702 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HDKPDFJJ_01703 2.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HDKPDFJJ_01704 3.3e-197 yqgU
HDKPDFJJ_01705 6.9e-50 yqgV S Thiamine-binding protein
HDKPDFJJ_01706 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HDKPDFJJ_01707 8e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HDKPDFJJ_01708 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HDKPDFJJ_01709 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HDKPDFJJ_01711 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDKPDFJJ_01712 4.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HDKPDFJJ_01713 5.2e-173 corA P Mg2 transporter protein
HDKPDFJJ_01715 1.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HDKPDFJJ_01716 1.1e-173 comGB NU COG1459 Type II secretory pathway, component PulF
HDKPDFJJ_01717 6.8e-47 comGC U Required for transformation and DNA binding
HDKPDFJJ_01718 5.4e-69 gspH NU protein transport across the cell outer membrane
HDKPDFJJ_01719 9e-59 comGE
HDKPDFJJ_01720 1.7e-34 comGF U Putative Competence protein ComGF
HDKPDFJJ_01721 3e-44 S ComG operon protein 7
HDKPDFJJ_01722 1.4e-26 yqzE S YqzE-like protein
HDKPDFJJ_01723 2.1e-53 yqzG S Protein of unknown function (DUF3889)
HDKPDFJJ_01724 5.1e-115 yqxM
HDKPDFJJ_01725 7.4e-58 sipW 3.4.21.89 U Signal peptidase
HDKPDFJJ_01726 1.9e-141 tasA S Cell division protein FtsN
HDKPDFJJ_01727 1e-54 sinR K transcriptional
HDKPDFJJ_01728 1.2e-24 sinI S Anti-repressor SinI
HDKPDFJJ_01729 7.1e-152 yqhG S Bacterial protein YqhG of unknown function
HDKPDFJJ_01730 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HDKPDFJJ_01731 2.4e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HDKPDFJJ_01732 6.4e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HDKPDFJJ_01733 4.1e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HDKPDFJJ_01734 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HDKPDFJJ_01735 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HDKPDFJJ_01736 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HDKPDFJJ_01737 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
HDKPDFJJ_01738 2.2e-61 yqhP
HDKPDFJJ_01739 3.4e-172 yqhQ S Protein of unknown function (DUF1385)
HDKPDFJJ_01740 6.6e-93 yqhR S Conserved membrane protein YqhR
HDKPDFJJ_01741 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HDKPDFJJ_01742 1.7e-172 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HDKPDFJJ_01743 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDKPDFJJ_01744 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HDKPDFJJ_01745 1e-170 spoIIIAA S stage III sporulation protein AA
HDKPDFJJ_01746 3.2e-84 spoIIIAB S Stage III sporulation protein
HDKPDFJJ_01747 7.6e-29 spoIIIAC S stage III sporulation protein AC
HDKPDFJJ_01748 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HDKPDFJJ_01749 8.4e-197 spoIIIAE S stage III sporulation protein AE
HDKPDFJJ_01750 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HDKPDFJJ_01751 6.9e-103 spoIIIAG S stage III sporulation protein AG
HDKPDFJJ_01752 1.6e-85 spoIIIAH S SpoIIIAH-like protein
HDKPDFJJ_01753 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDKPDFJJ_01754 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HDKPDFJJ_01755 1.8e-66 yqhY S protein conserved in bacteria
HDKPDFJJ_01756 7.4e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDKPDFJJ_01757 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDKPDFJJ_01758 8.4e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDKPDFJJ_01759 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDKPDFJJ_01760 6.5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDKPDFJJ_01761 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDKPDFJJ_01762 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HDKPDFJJ_01763 1.7e-78 argR K Regulates arginine biosynthesis genes
HDKPDFJJ_01764 1.9e-306 recN L May be involved in recombinational repair of damaged DNA
HDKPDFJJ_01765 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HDKPDFJJ_01766 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HDKPDFJJ_01768 2.3e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HDKPDFJJ_01769 6e-27
HDKPDFJJ_01770 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HDKPDFJJ_01771 1.1e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HDKPDFJJ_01772 1.3e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
HDKPDFJJ_01773 2.2e-154 hbdA 1.1.1.157 I Dehydrogenase
HDKPDFJJ_01774 4.8e-210 mmgC I acyl-CoA dehydrogenase
HDKPDFJJ_01775 3.5e-205 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HDKPDFJJ_01776 1.8e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HDKPDFJJ_01777 1.5e-161 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HDKPDFJJ_01778 4e-34 yqzF S Protein of unknown function (DUF2627)
HDKPDFJJ_01779 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HDKPDFJJ_01780 5.1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HDKPDFJJ_01781 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HDKPDFJJ_01782 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HDKPDFJJ_01783 1.4e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HDKPDFJJ_01784 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HDKPDFJJ_01785 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDKPDFJJ_01786 7.5e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDKPDFJJ_01787 2.6e-152 bmrR K helix_turn_helix, mercury resistance
HDKPDFJJ_01788 1.4e-207 norA EGP Major facilitator Superfamily
HDKPDFJJ_01789 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HDKPDFJJ_01790 9.3e-77 yqiW S Belongs to the UPF0403 family
HDKPDFJJ_01791 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HDKPDFJJ_01792 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HDKPDFJJ_01793 7.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HDKPDFJJ_01794 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
HDKPDFJJ_01795 2.3e-98 yqjB S protein conserved in bacteria
HDKPDFJJ_01797 4.2e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HDKPDFJJ_01798 1e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HDKPDFJJ_01799 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HDKPDFJJ_01800 1.3e-139 yqjF S Uncharacterized conserved protein (COG2071)
HDKPDFJJ_01801 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDKPDFJJ_01802 4.5e-24 yqzJ
HDKPDFJJ_01803 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDKPDFJJ_01804 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDKPDFJJ_01805 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDKPDFJJ_01806 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDKPDFJJ_01807 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDKPDFJJ_01808 1.7e-142 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HDKPDFJJ_01809 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HDKPDFJJ_01810 2.3e-311 rocB E arginine degradation protein
HDKPDFJJ_01811 1.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDKPDFJJ_01812 2.2e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HDKPDFJJ_01813 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_01814 7.1e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HDKPDFJJ_01815 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HDKPDFJJ_01816 2.1e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDKPDFJJ_01818 3.7e-224 yqjV G Major Facilitator Superfamily
HDKPDFJJ_01820 1.7e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDKPDFJJ_01821 1.7e-49 S YolD-like protein
HDKPDFJJ_01822 2e-85 yqjY K acetyltransferase
HDKPDFJJ_01823 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HDKPDFJJ_01824 1.1e-192 yqkA K GrpB protein
HDKPDFJJ_01825 2.8e-54 yqkB S Belongs to the HesB IscA family
HDKPDFJJ_01826 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HDKPDFJJ_01827 2.5e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HDKPDFJJ_01828 3.1e-12 yqkE S Protein of unknown function (DUF3886)
HDKPDFJJ_01829 1.8e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HDKPDFJJ_01831 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HDKPDFJJ_01832 9e-220 yqxK 3.6.4.12 L DNA helicase
HDKPDFJJ_01833 4.5e-58 ansR K Transcriptional regulator
HDKPDFJJ_01834 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HDKPDFJJ_01835 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HDKPDFJJ_01836 9.1e-235 mleN C Na H antiporter
HDKPDFJJ_01837 8e-241 mleA 1.1.1.38 C malic enzyme
HDKPDFJJ_01838 5.5e-30 yqkK
HDKPDFJJ_01839 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HDKPDFJJ_01840 2.4e-80 fur P Belongs to the Fur family
HDKPDFJJ_01841 3.7e-37 S Protein of unknown function (DUF4227)
HDKPDFJJ_01842 4.4e-166 xerD L recombinase XerD
HDKPDFJJ_01843 3.3e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HDKPDFJJ_01844 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HDKPDFJJ_01845 1.3e-210 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HDKPDFJJ_01846 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HDKPDFJJ_01847 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HDKPDFJJ_01848 9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDKPDFJJ_01849 9.6e-112 spoVAA S Stage V sporulation protein AA
HDKPDFJJ_01850 1e-67 spoVAB S Stage V sporulation protein AB
HDKPDFJJ_01851 2.3e-78 spoVAC S stage V sporulation protein AC
HDKPDFJJ_01852 9e-192 spoVAD I Stage V sporulation protein AD
HDKPDFJJ_01853 2.2e-57 spoVAEB S stage V sporulation protein
HDKPDFJJ_01854 1.4e-110 spoVAEA S stage V sporulation protein
HDKPDFJJ_01855 1.4e-273 spoVAF EG Stage V sporulation protein AF
HDKPDFJJ_01856 2.6e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDKPDFJJ_01857 3.6e-149 ypuA S Secreted protein
HDKPDFJJ_01858 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDKPDFJJ_01860 1.2e-07 eaeH M Domain of Unknown Function (DUF1259)
HDKPDFJJ_01862 3.4e-13 S PAP2 superfamily
HDKPDFJJ_01863 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HDKPDFJJ_01864 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HDKPDFJJ_01865 7.8e-55 ypuD
HDKPDFJJ_01866 1.1e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HDKPDFJJ_01867 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
HDKPDFJJ_01868 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HDKPDFJJ_01869 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HDKPDFJJ_01870 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDKPDFJJ_01871 1.2e-91 ypuF S Domain of unknown function (DUF309)
HDKPDFJJ_01872 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDKPDFJJ_01873 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDKPDFJJ_01874 7.6e-97 ypuI S Protein of unknown function (DUF3907)
HDKPDFJJ_01875 1.5e-211 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HDKPDFJJ_01876 3.5e-103 spmA S Spore maturation protein
HDKPDFJJ_01877 1.9e-87 spmB S Spore maturation protein
HDKPDFJJ_01878 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDKPDFJJ_01879 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HDKPDFJJ_01880 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HDKPDFJJ_01881 2.6e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HDKPDFJJ_01882 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_01883 0.0 resE 2.7.13.3 T Histidine kinase
HDKPDFJJ_01884 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HDKPDFJJ_01885 1.5e-200 rsiX
HDKPDFJJ_01886 5.5e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDKPDFJJ_01887 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDKPDFJJ_01888 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDKPDFJJ_01889 4.7e-41 fer C Ferredoxin
HDKPDFJJ_01890 1.8e-198 ypbB 5.1.3.1 S protein conserved in bacteria
HDKPDFJJ_01891 9.2e-286 recQ 3.6.4.12 L DNA helicase
HDKPDFJJ_01892 1.1e-99 ypbD S metal-dependent membrane protease
HDKPDFJJ_01893 3.9e-80 ypbE M Lysin motif
HDKPDFJJ_01894 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HDKPDFJJ_01895 6.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HDKPDFJJ_01896 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HDKPDFJJ_01897 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HDKPDFJJ_01898 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HDKPDFJJ_01899 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
HDKPDFJJ_01900 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HDKPDFJJ_01901 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HDKPDFJJ_01902 3.9e-111 ypfA M Flagellar protein YcgR
HDKPDFJJ_01903 1.8e-23 S Family of unknown function (DUF5359)
HDKPDFJJ_01904 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HDKPDFJJ_01905 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HDKPDFJJ_01906 3.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDKPDFJJ_01907 1e-07 S YpzI-like protein
HDKPDFJJ_01908 3.9e-102 yphA
HDKPDFJJ_01909 3.3e-161 seaA S YIEGIA protein
HDKPDFJJ_01910 2.1e-28 ypzH
HDKPDFJJ_01911 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HDKPDFJJ_01912 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HDKPDFJJ_01913 1.2e-18 yphE S Protein of unknown function (DUF2768)
HDKPDFJJ_01914 6e-137 yphF
HDKPDFJJ_01915 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HDKPDFJJ_01916 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDKPDFJJ_01917 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HDKPDFJJ_01918 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HDKPDFJJ_01919 8.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HDKPDFJJ_01920 7.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HDKPDFJJ_01921 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDKPDFJJ_01922 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HDKPDFJJ_01923 4.2e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HDKPDFJJ_01924 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDKPDFJJ_01925 1.7e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDKPDFJJ_01926 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HDKPDFJJ_01927 2.1e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HDKPDFJJ_01928 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HDKPDFJJ_01929 4.3e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HDKPDFJJ_01930 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HDKPDFJJ_01931 2.2e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HDKPDFJJ_01932 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HDKPDFJJ_01933 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDKPDFJJ_01934 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HDKPDFJJ_01935 2.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HDKPDFJJ_01936 4.1e-234 S COG0457 FOG TPR repeat
HDKPDFJJ_01937 2.8e-99 ypiB S Belongs to the UPF0302 family
HDKPDFJJ_01938 2.7e-76 ypiF S Protein of unknown function (DUF2487)
HDKPDFJJ_01939 1.1e-96 qcrA C Menaquinol-cytochrome c reductase
HDKPDFJJ_01940 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HDKPDFJJ_01941 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HDKPDFJJ_01942 3.1e-99 ypjA S membrane
HDKPDFJJ_01943 1.5e-141 ypjB S sporulation protein
HDKPDFJJ_01944 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HDKPDFJJ_01945 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HDKPDFJJ_01946 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDKPDFJJ_01947 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HDKPDFJJ_01948 4.9e-128 bshB1 S proteins, LmbE homologs
HDKPDFJJ_01949 7.7e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HDKPDFJJ_01950 4.6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDKPDFJJ_01951 3.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDKPDFJJ_01952 5.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HDKPDFJJ_01953 1.4e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HDKPDFJJ_01954 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HDKPDFJJ_01955 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HDKPDFJJ_01956 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HDKPDFJJ_01957 2.2e-79 ypmB S protein conserved in bacteria
HDKPDFJJ_01958 6.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HDKPDFJJ_01959 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HDKPDFJJ_01960 5.7e-129 dnaD L DNA replication protein DnaD
HDKPDFJJ_01961 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDKPDFJJ_01962 4.7e-93 ypoC
HDKPDFJJ_01963 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HDKPDFJJ_01964 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDKPDFJJ_01965 2.8e-187 yppC S Protein of unknown function (DUF2515)
HDKPDFJJ_01968 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
HDKPDFJJ_01970 1e-47 yppG S YppG-like protein
HDKPDFJJ_01971 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
HDKPDFJJ_01972 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HDKPDFJJ_01973 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HDKPDFJJ_01974 9.5e-236 yprB L RNase_H superfamily
HDKPDFJJ_01975 2.8e-91 ypsA S Belongs to the UPF0398 family
HDKPDFJJ_01976 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDKPDFJJ_01977 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HDKPDFJJ_01979 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HDKPDFJJ_01980 2.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDKPDFJJ_01981 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HDKPDFJJ_01982 2.2e-185 ptxS K transcriptional
HDKPDFJJ_01983 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HDKPDFJJ_01984 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HDKPDFJJ_01985 6.6e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HDKPDFJJ_01986 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HDKPDFJJ_01987 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDKPDFJJ_01988 9.5e-226 pbuX F xanthine
HDKPDFJJ_01989 1.4e-206 bcsA Q Naringenin-chalcone synthase
HDKPDFJJ_01990 6.7e-87 ypbQ S protein conserved in bacteria
HDKPDFJJ_01991 0.0 ypbR S Dynamin family
HDKPDFJJ_01992 1e-38 ypbS S Protein of unknown function (DUF2533)
HDKPDFJJ_01993 2e-07
HDKPDFJJ_01994 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HDKPDFJJ_01996 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
HDKPDFJJ_01997 1.5e-104 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HDKPDFJJ_01998 8.3e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HDKPDFJJ_01999 3e-29 ypeQ S Zinc-finger
HDKPDFJJ_02000 8.1e-31 S Protein of unknown function (DUF2564)
HDKPDFJJ_02001 3.8e-16 degR
HDKPDFJJ_02002 7.9e-31 cspD K Cold-shock protein
HDKPDFJJ_02003 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HDKPDFJJ_02005 8.1e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HDKPDFJJ_02006 6.8e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HDKPDFJJ_02007 1.2e-106 ypgQ S phosphohydrolase
HDKPDFJJ_02008 2.2e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
HDKPDFJJ_02009 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HDKPDFJJ_02010 1.7e-75 yphP S Belongs to the UPF0403 family
HDKPDFJJ_02011 1.7e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HDKPDFJJ_02012 2.5e-112 ypjP S YpjP-like protein
HDKPDFJJ_02013 1.2e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HDKPDFJJ_02014 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDKPDFJJ_02015 1.5e-94 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDKPDFJJ_02016 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HDKPDFJJ_02017 4.2e-110 hlyIII S protein, Hemolysin III
HDKPDFJJ_02018 6.1e-185 pspF K Transcriptional regulator
HDKPDFJJ_02019 2e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HDKPDFJJ_02020 8.9e-40 ypmP S Protein of unknown function (DUF2535)
HDKPDFJJ_02021 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HDKPDFJJ_02022 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HDKPDFJJ_02023 1.1e-98 ypmS S protein conserved in bacteria
HDKPDFJJ_02024 1.2e-28 ypmT S Uncharacterized ympT
HDKPDFJJ_02025 1.7e-222 mepA V MATE efflux family protein
HDKPDFJJ_02026 1.6e-70 ypoP K transcriptional
HDKPDFJJ_02027 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDKPDFJJ_02028 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HDKPDFJJ_02029 4.3e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HDKPDFJJ_02030 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HDKPDFJJ_02031 6.3e-187 cgeB S Spore maturation protein
HDKPDFJJ_02032 1.2e-65 cgeA
HDKPDFJJ_02033 3.5e-38 cgeC
HDKPDFJJ_02034 6.8e-253 cgeD M maturation of the outermost layer of the spore
HDKPDFJJ_02035 1.8e-144 yiiD K acetyltransferase
HDKPDFJJ_02037 2.2e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDKPDFJJ_02038 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HDKPDFJJ_02039 1.2e-115 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HDKPDFJJ_02040 1.5e-255 yodQ 3.5.1.16 E Acetylornithine deacetylase
HDKPDFJJ_02041 2.3e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HDKPDFJJ_02042 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HDKPDFJJ_02043 7e-46 yokU S YokU-like protein, putative antitoxin
HDKPDFJJ_02044 1.4e-36 yozE S Belongs to the UPF0346 family
HDKPDFJJ_02045 6e-123 yodN
HDKPDFJJ_02047 2.8e-24 yozD S YozD-like protein
HDKPDFJJ_02048 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
HDKPDFJJ_02049 3.6e-54 yodL S YodL-like
HDKPDFJJ_02050 5.3e-09
HDKPDFJJ_02051 9.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HDKPDFJJ_02052 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HDKPDFJJ_02053 1.5e-23 yodI
HDKPDFJJ_02054 6.3e-128 yodH Q Methyltransferase
HDKPDFJJ_02055 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HDKPDFJJ_02056 1.6e-91 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDKPDFJJ_02057 6.2e-28 S Protein of unknown function (DUF3311)
HDKPDFJJ_02058 6.4e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
HDKPDFJJ_02059 3.8e-113 mhqD S Carboxylesterase
HDKPDFJJ_02060 1.4e-107 yodC C nitroreductase
HDKPDFJJ_02061 4.4e-55 yodB K transcriptional
HDKPDFJJ_02062 8e-64 yodA S tautomerase
HDKPDFJJ_02063 4.2e-205 gntP EG COG2610 H gluconate symporter and related permeases
HDKPDFJJ_02064 3.4e-09
HDKPDFJJ_02065 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
HDKPDFJJ_02066 1.9e-161 rarD S -transporter
HDKPDFJJ_02067 1.5e-43
HDKPDFJJ_02068 2.2e-60 yojF S Protein of unknown function (DUF1806)
HDKPDFJJ_02069 2.1e-125 yojG S deacetylase
HDKPDFJJ_02070 4.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDKPDFJJ_02071 2.3e-243 norM V Multidrug efflux pump
HDKPDFJJ_02073 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDKPDFJJ_02074 1.2e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HDKPDFJJ_02075 1.4e-191 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HDKPDFJJ_02076 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HDKPDFJJ_02077 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
HDKPDFJJ_02078 0.0 yojO P Von Willebrand factor
HDKPDFJJ_02079 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HDKPDFJJ_02080 9.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HDKPDFJJ_02081 1.1e-167 yocS S -transporter
HDKPDFJJ_02082 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HDKPDFJJ_02083 6e-165 sodA 1.15.1.1 P Superoxide dismutase
HDKPDFJJ_02084 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HDKPDFJJ_02085 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HDKPDFJJ_02086 2.7e-31 yozC
HDKPDFJJ_02087 4.2e-56 yozO S Bacterial PH domain
HDKPDFJJ_02088 1.9e-36 yocN
HDKPDFJJ_02089 1.1e-40 yozN
HDKPDFJJ_02090 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HDKPDFJJ_02091 6.2e-32
HDKPDFJJ_02092 5.4e-53 yocL
HDKPDFJJ_02093 3.3e-83 dksA T general stress protein
HDKPDFJJ_02094 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDKPDFJJ_02096 0.0 recQ 3.6.4.12 L DNA helicase
HDKPDFJJ_02097 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HDKPDFJJ_02098 6.5e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDKPDFJJ_02099 7.1e-198 desK 2.7.13.3 T Histidine kinase
HDKPDFJJ_02100 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HDKPDFJJ_02101 7.1e-186 yocD 3.4.17.13 V peptidase S66
HDKPDFJJ_02102 1.5e-91 yocC
HDKPDFJJ_02103 3.3e-141
HDKPDFJJ_02104 1.5e-92 yozB S membrane
HDKPDFJJ_02105 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HDKPDFJJ_02106 1e-51 czrA K transcriptional
HDKPDFJJ_02107 1.8e-90 yobW
HDKPDFJJ_02108 6e-174 yobV K WYL domain
HDKPDFJJ_02109 1.6e-82 yobU K Bacterial transcription activator, effector binding domain
HDKPDFJJ_02110 7.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HDKPDFJJ_02111 6.9e-96 yobS K Transcriptional regulator
HDKPDFJJ_02112 3.1e-141 yobR 2.3.1.1 J FR47-like protein
HDKPDFJJ_02113 6.1e-134 yobQ K helix_turn_helix, arabinose operon control protein
HDKPDFJJ_02114 3.5e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HDKPDFJJ_02115 3.7e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HDKPDFJJ_02116 2.4e-101 yokH G SMI1 / KNR4 family
HDKPDFJJ_02117 4.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HDKPDFJJ_02118 6.9e-19
HDKPDFJJ_02120 1.8e-27 S response regulator aspartate phosphatase
HDKPDFJJ_02122 1.4e-33 yoqW S Belongs to the SOS response-associated peptidase family
HDKPDFJJ_02123 2.2e-63 yoaQ S Evidence 4 Homologs of previously reported genes of
HDKPDFJJ_02124 3.8e-54 K Helix-turn-helix
HDKPDFJJ_02125 1.4e-37 S TM2 domain
HDKPDFJJ_02126 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HDKPDFJJ_02127 6.1e-280 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HDKPDFJJ_02128 1.8e-201 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HDKPDFJJ_02131 4.1e-167 bla 3.5.2.6 V beta-lactamase
HDKPDFJJ_02132 1e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HDKPDFJJ_02133 1.3e-75 yoaW
HDKPDFJJ_02134 2e-155 yijE EG EamA-like transporter family
HDKPDFJJ_02135 2.8e-157 yoaU K LysR substrate binding domain
HDKPDFJJ_02136 3.1e-147 yoaT S Protein of unknown function (DUF817)
HDKPDFJJ_02137 4.4e-30 yozG K Transcriptional regulator
HDKPDFJJ_02138 3.6e-74 yoaS S Protein of unknown function (DUF2975)
HDKPDFJJ_02139 7.1e-172 yoaR V vancomycin resistance protein
HDKPDFJJ_02140 4e-84
HDKPDFJJ_02143 8.7e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
HDKPDFJJ_02146 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
HDKPDFJJ_02147 8.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HDKPDFJJ_02148 2.6e-110 yoaK S Membrane
HDKPDFJJ_02149 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HDKPDFJJ_02150 1.4e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HDKPDFJJ_02151 2.7e-180 mcpU NT methyl-accepting chemotaxis protein
HDKPDFJJ_02152 8.2e-37 S Protein of unknown function (DUF4025)
HDKPDFJJ_02153 2.6e-13
HDKPDFJJ_02154 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
HDKPDFJJ_02155 1.1e-33 yoaF
HDKPDFJJ_02156 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDKPDFJJ_02157 1.3e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDKPDFJJ_02158 1.3e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HDKPDFJJ_02159 1.2e-233 yoaB EGP Major facilitator Superfamily
HDKPDFJJ_02160 2.7e-94 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HDKPDFJJ_02161 1.3e-134 yoxB
HDKPDFJJ_02162 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
HDKPDFJJ_02163 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_02164 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HDKPDFJJ_02165 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDKPDFJJ_02166 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDKPDFJJ_02167 7.8e-155 gltC K Transcriptional regulator
HDKPDFJJ_02168 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HDKPDFJJ_02169 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HDKPDFJJ_02170 2.8e-182 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HDKPDFJJ_02171 1.7e-17 gltR1 K Transcriptional regulator
HDKPDFJJ_02172 1.6e-123 gltR1 K Transcriptional regulator
HDKPDFJJ_02173 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HDKPDFJJ_02174 3e-34 yoeD G Helix-turn-helix domain
HDKPDFJJ_02175 6.5e-96 L Integrase
HDKPDFJJ_02177 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HDKPDFJJ_02178 2.3e-246 yoeA V MATE efflux family protein
HDKPDFJJ_02179 8.4e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
HDKPDFJJ_02180 9.8e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HDKPDFJJ_02181 8e-91 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDKPDFJJ_02182 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDKPDFJJ_02183 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HDKPDFJJ_02184 1.1e-63 yngL S Protein of unknown function (DUF1360)
HDKPDFJJ_02185 2e-304 yngK T Glycosyl hydrolase-like 10
HDKPDFJJ_02186 1.6e-11 K Bacterial regulatory proteins, tetR family
HDKPDFJJ_02188 6.3e-32 S Family of unknown function (DUF5367)
HDKPDFJJ_02189 9.8e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HDKPDFJJ_02190 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HDKPDFJJ_02191 1.1e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HDKPDFJJ_02192 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HDKPDFJJ_02193 1.2e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HDKPDFJJ_02194 5.4e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HDKPDFJJ_02195 1.3e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HDKPDFJJ_02196 2.1e-232 nrnB S phosphohydrolase (DHH superfamily)
HDKPDFJJ_02197 1.2e-103 yngC S membrane-associated protein
HDKPDFJJ_02198 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDKPDFJJ_02199 1.6e-79 yngA S membrane
HDKPDFJJ_02200 4.4e-291 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HDKPDFJJ_02201 7.2e-247 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HDKPDFJJ_02202 2.6e-211 S Platelet-activating factor acetylhydrolase, isoform II
HDKPDFJJ_02204 1.4e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HDKPDFJJ_02205 5.3e-251 agcS E Sodium alanine symporter
HDKPDFJJ_02206 1.3e-57 ynfC
HDKPDFJJ_02207 2.3e-12
HDKPDFJJ_02208 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDKPDFJJ_02209 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDKPDFJJ_02210 6.6e-69 yccU S CoA-binding protein
HDKPDFJJ_02211 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDKPDFJJ_02212 4.1e-49 yneR S Belongs to the HesB IscA family
HDKPDFJJ_02213 4.9e-53 yneQ
HDKPDFJJ_02214 1.2e-73 yneP S Thioesterase-like superfamily
HDKPDFJJ_02215 3.9e-35 tlp S Belongs to the Tlp family
HDKPDFJJ_02216 3.1e-08 sspN S Small acid-soluble spore protein N family
HDKPDFJJ_02218 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HDKPDFJJ_02219 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HDKPDFJJ_02220 2.5e-14 sspO S Belongs to the SspO family
HDKPDFJJ_02221 3.9e-19 sspP S Belongs to the SspP family
HDKPDFJJ_02222 2.2e-63 hspX O Spore coat protein
HDKPDFJJ_02223 4.2e-74 yneK S Protein of unknown function (DUF2621)
HDKPDFJJ_02224 1.9e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HDKPDFJJ_02225 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HDKPDFJJ_02226 1.2e-126 ccdA O cytochrome c biogenesis protein
HDKPDFJJ_02227 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HDKPDFJJ_02228 1.8e-28 yneF S UPF0154 protein
HDKPDFJJ_02229 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HDKPDFJJ_02230 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDKPDFJJ_02231 1.4e-31 ynzC S UPF0291 protein
HDKPDFJJ_02232 3.6e-109 yneB L resolvase
HDKPDFJJ_02233 7.6e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HDKPDFJJ_02234 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDKPDFJJ_02235 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HDKPDFJJ_02236 5.8e-74 yndM S Protein of unknown function (DUF2512)
HDKPDFJJ_02237 8.1e-137 yndL S Replication protein
HDKPDFJJ_02239 8.5e-309 yndJ S YndJ-like protein
HDKPDFJJ_02240 7.1e-115 yndH S Domain of unknown function (DUF4166)
HDKPDFJJ_02241 1.8e-150 yndG S DoxX-like family
HDKPDFJJ_02242 1.1e-212 gerLC S Spore germination protein
HDKPDFJJ_02243 2.1e-194 gerAB U Spore germination
HDKPDFJJ_02244 3.2e-281 gerAA EG Spore germination protein
HDKPDFJJ_02247 2e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HDKPDFJJ_02248 2.6e-70
HDKPDFJJ_02249 6.7e-24 tatA U protein secretion
HDKPDFJJ_02252 1.7e-120 S Domain of unknown function, YrpD
HDKPDFJJ_02254 3e-164 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDKPDFJJ_02257 5.2e-15
HDKPDFJJ_02258 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HDKPDFJJ_02259 1.9e-80 yncE S Protein of unknown function (DUF2691)
HDKPDFJJ_02261 3.8e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDKPDFJJ_02262 3e-246 iolT EGP Major facilitator Superfamily
HDKPDFJJ_02263 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
HDKPDFJJ_02264 3.4e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HDKPDFJJ_02265 2.1e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HDKPDFJJ_02266 1.4e-212 xylR GK ROK family
HDKPDFJJ_02267 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HDKPDFJJ_02268 3.5e-255 xynT G MFS/sugar transport protein
HDKPDFJJ_02269 5.5e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HDKPDFJJ_02272 1.3e-77 S CAAX protease self-immunity
HDKPDFJJ_02274 6.8e-98 ynaD J Acetyltransferase (GNAT) domain
HDKPDFJJ_02275 1.3e-08 S Protein of unknown function (DUF1433)
HDKPDFJJ_02276 2.1e-103 ynaC
HDKPDFJJ_02277 1.1e-10 ynaC
HDKPDFJJ_02278 9.8e-89 G SMI1-KNR4 cell-wall
HDKPDFJJ_02279 3.2e-37
HDKPDFJJ_02280 4.6e-31
HDKPDFJJ_02281 3.8e-10
HDKPDFJJ_02283 3.7e-77 M nucleic acid phosphodiester bond hydrolysis
HDKPDFJJ_02284 7e-113 M nucleic acid phosphodiester bond hydrolysis
HDKPDFJJ_02285 3e-31
HDKPDFJJ_02286 7e-261 glnA 6.3.1.2 E glutamine synthetase
HDKPDFJJ_02287 1.1e-68 glnR K transcriptional
HDKPDFJJ_02288 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HDKPDFJJ_02289 7.9e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDKPDFJJ_02290 1.7e-176 spoVK O stage V sporulation protein K
HDKPDFJJ_02291 8.8e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HDKPDFJJ_02292 2e-109 ymaB
HDKPDFJJ_02293 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDKPDFJJ_02294 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDKPDFJJ_02295 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HDKPDFJJ_02296 4.5e-22 ymzA
HDKPDFJJ_02297 8.2e-23
HDKPDFJJ_02298 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HDKPDFJJ_02299 2.3e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDKPDFJJ_02300 2.1e-46 ymaF S YmaF family
HDKPDFJJ_02302 4.1e-50 ebrA P Small Multidrug Resistance protein
HDKPDFJJ_02303 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HDKPDFJJ_02304 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
HDKPDFJJ_02305 2.1e-126 ymaC S Replication protein
HDKPDFJJ_02306 1.9e-07 K Transcriptional regulator
HDKPDFJJ_02307 8.6e-251 aprX O Belongs to the peptidase S8 family
HDKPDFJJ_02308 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
HDKPDFJJ_02309 2.9e-60 ymzB
HDKPDFJJ_02310 3.1e-231 cypA C Cytochrome P450
HDKPDFJJ_02311 0.0 pks13 HQ Beta-ketoacyl synthase
HDKPDFJJ_02312 0.0 dhbF IQ polyketide synthase
HDKPDFJJ_02313 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HDKPDFJJ_02314 0.0 pfaA Q Polyketide synthase of type I
HDKPDFJJ_02315 0.0 rhiB IQ polyketide synthase
HDKPDFJJ_02316 2.3e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HDKPDFJJ_02317 1.2e-140 pksH 4.2.1.18 I enoyl-CoA hydratase
HDKPDFJJ_02318 5.1e-245 pksG 2.3.3.10 I synthase
HDKPDFJJ_02319 3.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDKPDFJJ_02320 1.4e-37 acpK IQ Phosphopantetheine attachment site
HDKPDFJJ_02321 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HDKPDFJJ_02322 6e-185 pksD Q Acyl transferase domain
HDKPDFJJ_02324 9.2e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HDKPDFJJ_02325 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HDKPDFJJ_02326 4.4e-109 pksA K Transcriptional regulator
HDKPDFJJ_02327 3.5e-97 ymcC S Membrane
HDKPDFJJ_02329 4.1e-67 S Regulatory protein YrvL
HDKPDFJJ_02330 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDKPDFJJ_02331 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDKPDFJJ_02332 2.2e-88 cotE S Spore coat protein
HDKPDFJJ_02333 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HDKPDFJJ_02334 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HDKPDFJJ_02335 2.3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HDKPDFJJ_02336 2.1e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HDKPDFJJ_02337 1.2e-36 spoVS S Stage V sporulation protein S
HDKPDFJJ_02338 1.9e-152 ymdB S protein conserved in bacteria
HDKPDFJJ_02339 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HDKPDFJJ_02340 9.1e-212 pbpX V Beta-lactamase
HDKPDFJJ_02341 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDKPDFJJ_02342 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
HDKPDFJJ_02343 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDKPDFJJ_02344 3.5e-118 ymfM S protein conserved in bacteria
HDKPDFJJ_02345 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HDKPDFJJ_02346 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HDKPDFJJ_02347 3e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HDKPDFJJ_02348 1.1e-239 ymfH S zinc protease
HDKPDFJJ_02349 1.6e-233 ymfF S Peptidase M16
HDKPDFJJ_02350 3.8e-205 ymfD EGP Major facilitator Superfamily
HDKPDFJJ_02351 1.4e-133 ymfC K Transcriptional regulator
HDKPDFJJ_02352 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HDKPDFJJ_02353 4.4e-32 S YlzJ-like protein
HDKPDFJJ_02354 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HDKPDFJJ_02355 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDKPDFJJ_02356 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDKPDFJJ_02357 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HDKPDFJJ_02358 1.9e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDKPDFJJ_02359 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HDKPDFJJ_02360 1.9e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HDKPDFJJ_02361 2.6e-42 ymxH S YlmC YmxH family
HDKPDFJJ_02362 4.4e-233 pepR S Belongs to the peptidase M16 family
HDKPDFJJ_02363 3.6e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HDKPDFJJ_02364 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HDKPDFJJ_02365 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDKPDFJJ_02366 4.3e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HDKPDFJJ_02367 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDKPDFJJ_02368 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDKPDFJJ_02369 3e-44 ylxP S protein conserved in bacteria
HDKPDFJJ_02370 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDKPDFJJ_02371 3.1e-47 ylxQ J ribosomal protein
HDKPDFJJ_02372 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HDKPDFJJ_02373 1.1e-203 nusA K Participates in both transcription termination and antitermination
HDKPDFJJ_02374 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HDKPDFJJ_02375 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDKPDFJJ_02376 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDKPDFJJ_02377 1.7e-232 rasP M zinc metalloprotease
HDKPDFJJ_02378 1.3e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HDKPDFJJ_02379 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HDKPDFJJ_02380 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDKPDFJJ_02381 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDKPDFJJ_02382 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HDKPDFJJ_02383 2.4e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDKPDFJJ_02384 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HDKPDFJJ_02385 5.3e-76 ylxL
HDKPDFJJ_02386 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDKPDFJJ_02387 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HDKPDFJJ_02388 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HDKPDFJJ_02389 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HDKPDFJJ_02390 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HDKPDFJJ_02391 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HDKPDFJJ_02392 1.7e-157 flhG D Belongs to the ParA family
HDKPDFJJ_02393 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
HDKPDFJJ_02394 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HDKPDFJJ_02395 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HDKPDFJJ_02396 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HDKPDFJJ_02397 2.2e-36 fliQ N Role in flagellar biosynthesis
HDKPDFJJ_02398 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HDKPDFJJ_02399 1.3e-95 fliZ N Flagellar biosynthesis protein, FliO
HDKPDFJJ_02400 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HDKPDFJJ_02401 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HDKPDFJJ_02402 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HDKPDFJJ_02403 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HDKPDFJJ_02404 1.9e-136 flgG N Flagellar basal body rod
HDKPDFJJ_02405 2.3e-72 flgD N Flagellar basal body rod modification protein
HDKPDFJJ_02406 7.1e-214 fliK N Flagellar hook-length control protein
HDKPDFJJ_02407 7.7e-37 ylxF S MgtE intracellular N domain
HDKPDFJJ_02408 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HDKPDFJJ_02409 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HDKPDFJJ_02410 5.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HDKPDFJJ_02411 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HDKPDFJJ_02412 3.5e-254 fliF N The M ring may be actively involved in energy transduction
HDKPDFJJ_02413 1.9e-31 fliE N Flagellar hook-basal body
HDKPDFJJ_02414 2e-74 flgC N Belongs to the flagella basal body rod proteins family
HDKPDFJJ_02415 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HDKPDFJJ_02416 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HDKPDFJJ_02417 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDKPDFJJ_02418 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDKPDFJJ_02419 5.7e-169 xerC L tyrosine recombinase XerC
HDKPDFJJ_02420 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDKPDFJJ_02421 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDKPDFJJ_02422 4e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HDKPDFJJ_02423 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HDKPDFJJ_02424 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HDKPDFJJ_02425 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HDKPDFJJ_02426 1.5e-284 ylqG
HDKPDFJJ_02427 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDKPDFJJ_02428 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDKPDFJJ_02429 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDKPDFJJ_02430 4.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HDKPDFJJ_02431 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDKPDFJJ_02432 1.4e-60 ylqD S YlqD protein
HDKPDFJJ_02433 4.5e-36 ylqC S Belongs to the UPF0109 family
HDKPDFJJ_02434 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HDKPDFJJ_02435 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDKPDFJJ_02436 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDKPDFJJ_02437 2.9e-87
HDKPDFJJ_02438 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDKPDFJJ_02439 0.0 smc D Required for chromosome condensation and partitioning
HDKPDFJJ_02440 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDKPDFJJ_02441 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDKPDFJJ_02442 1.4e-128 IQ reductase
HDKPDFJJ_02443 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HDKPDFJJ_02444 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDKPDFJJ_02445 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HDKPDFJJ_02446 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDKPDFJJ_02447 1.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
HDKPDFJJ_02448 5.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HDKPDFJJ_02449 1.7e-301 yloV S kinase related to dihydroxyacetone kinase
HDKPDFJJ_02450 5.5e-59 asp S protein conserved in bacteria
HDKPDFJJ_02451 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HDKPDFJJ_02452 1.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
HDKPDFJJ_02453 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HDKPDFJJ_02454 7.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDKPDFJJ_02455 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HDKPDFJJ_02456 1.6e-140 stp 3.1.3.16 T phosphatase
HDKPDFJJ_02457 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HDKPDFJJ_02458 4.6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDKPDFJJ_02459 5.5e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDKPDFJJ_02460 7.3e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDKPDFJJ_02461 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDKPDFJJ_02462 2.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDKPDFJJ_02463 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDKPDFJJ_02464 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HDKPDFJJ_02465 1.5e-40 ylzA S Belongs to the UPF0296 family
HDKPDFJJ_02466 2.4e-156 yloC S stress-induced protein
HDKPDFJJ_02467 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HDKPDFJJ_02468 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HDKPDFJJ_02469 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HDKPDFJJ_02470 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HDKPDFJJ_02471 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HDKPDFJJ_02472 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HDKPDFJJ_02473 4.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HDKPDFJJ_02474 9.2e-179 cysP P phosphate transporter
HDKPDFJJ_02475 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HDKPDFJJ_02477 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDKPDFJJ_02478 3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDKPDFJJ_02479 5.4e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDKPDFJJ_02480 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HDKPDFJJ_02481 0.0 carB 6.3.5.5 F Belongs to the CarB family
HDKPDFJJ_02482 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDKPDFJJ_02483 2e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDKPDFJJ_02484 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HDKPDFJJ_02485 7.6e-231 pyrP F Xanthine uracil
HDKPDFJJ_02486 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDKPDFJJ_02487 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDKPDFJJ_02488 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDKPDFJJ_02489 1.3e-63 dksA T COG1734 DnaK suppressor protein
HDKPDFJJ_02490 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDKPDFJJ_02491 2.6e-67 divIVA D Cell division initiation protein
HDKPDFJJ_02492 3.3e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HDKPDFJJ_02493 1.3e-39 yggT S membrane
HDKPDFJJ_02494 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDKPDFJJ_02495 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HDKPDFJJ_02496 5.9e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HDKPDFJJ_02497 2.4e-37 ylmC S sporulation protein
HDKPDFJJ_02498 7.5e-252 argE 3.5.1.16 E Acetylornithine deacetylase
HDKPDFJJ_02499 1.2e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HDKPDFJJ_02500 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDKPDFJJ_02501 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDKPDFJJ_02502 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HDKPDFJJ_02503 0.0 bpr O COG1404 Subtilisin-like serine proteases
HDKPDFJJ_02504 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDKPDFJJ_02505 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDKPDFJJ_02506 6.2e-58 sbp S small basic protein
HDKPDFJJ_02507 1e-102 ylxX S protein conserved in bacteria
HDKPDFJJ_02508 2.4e-103 ylxW S protein conserved in bacteria
HDKPDFJJ_02509 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDKPDFJJ_02510 5.3e-167 murB 1.3.1.98 M cell wall formation
HDKPDFJJ_02511 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDKPDFJJ_02512 9.8e-186 spoVE D Belongs to the SEDS family
HDKPDFJJ_02513 4.5e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDKPDFJJ_02514 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDKPDFJJ_02515 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDKPDFJJ_02516 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HDKPDFJJ_02517 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HDKPDFJJ_02518 3.7e-44 ftsL D Essential cell division protein
HDKPDFJJ_02519 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDKPDFJJ_02520 4.2e-77 mraZ K Belongs to the MraZ family
HDKPDFJJ_02521 2.1e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HDKPDFJJ_02522 4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDKPDFJJ_02523 4e-89 ylbP K n-acetyltransferase
HDKPDFJJ_02524 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HDKPDFJJ_02525 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HDKPDFJJ_02526 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HDKPDFJJ_02528 2.3e-229 ylbM S Belongs to the UPF0348 family
HDKPDFJJ_02529 7.5e-186 ylbL T Belongs to the peptidase S16 family
HDKPDFJJ_02530 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HDKPDFJJ_02531 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
HDKPDFJJ_02532 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDKPDFJJ_02533 2.1e-97 rsmD 2.1.1.171 L Methyltransferase
HDKPDFJJ_02534 3.7e-38 ylbG S UPF0298 protein
HDKPDFJJ_02535 1.8e-75 ylbF S Belongs to the UPF0342 family
HDKPDFJJ_02536 6.7e-37 ylbE S YlbE-like protein
HDKPDFJJ_02537 4.5e-62 ylbD S Putative coat protein
HDKPDFJJ_02538 2.8e-199 ylbC S protein with SCP PR1 domains
HDKPDFJJ_02539 2.6e-74 ylbB T COG0517 FOG CBS domain
HDKPDFJJ_02540 7e-62 ylbA S YugN-like family
HDKPDFJJ_02541 8.8e-167 ctaG S cytochrome c oxidase
HDKPDFJJ_02542 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HDKPDFJJ_02543 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HDKPDFJJ_02544 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HDKPDFJJ_02545 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HDKPDFJJ_02546 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HDKPDFJJ_02547 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HDKPDFJJ_02548 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HDKPDFJJ_02549 2.7e-211 ftsW D Belongs to the SEDS family
HDKPDFJJ_02550 8.7e-44 ylaN S Belongs to the UPF0358 family
HDKPDFJJ_02551 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HDKPDFJJ_02552 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HDKPDFJJ_02553 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HDKPDFJJ_02554 1.8e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDKPDFJJ_02555 2.5e-32 ylaI S protein conserved in bacteria
HDKPDFJJ_02556 4.2e-47 ylaH S YlaH-like protein
HDKPDFJJ_02557 0.0 typA T GTP-binding protein TypA
HDKPDFJJ_02558 8.2e-22 S Family of unknown function (DUF5325)
HDKPDFJJ_02559 5.9e-37 ylaE
HDKPDFJJ_02560 9.1e-12 sigC S Putative zinc-finger
HDKPDFJJ_02561 2.8e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HDKPDFJJ_02562 3e-41 ylaB
HDKPDFJJ_02563 0.0 ylaA
HDKPDFJJ_02564 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HDKPDFJJ_02565 2.7e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HDKPDFJJ_02566 2e-77 ykzC S Acetyltransferase (GNAT) family
HDKPDFJJ_02567 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
HDKPDFJJ_02568 7.2e-26 ykzI
HDKPDFJJ_02569 2.1e-117 yktB S Belongs to the UPF0637 family
HDKPDFJJ_02570 1e-41 yktA S Belongs to the UPF0223 family
HDKPDFJJ_02571 1e-276 speA 4.1.1.19 E Arginine
HDKPDFJJ_02572 2.7e-10 S SR1 protein
HDKPDFJJ_02573 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HDKPDFJJ_02574 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HDKPDFJJ_02575 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDKPDFJJ_02576 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDKPDFJJ_02577 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HDKPDFJJ_02578 6.1e-93 recN L Putative cell-wall binding lipoprotein
HDKPDFJJ_02580 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDKPDFJJ_02581 5.5e-147 ykrA S hydrolases of the HAD superfamily
HDKPDFJJ_02582 8.2e-31 ykzG S Belongs to the UPF0356 family
HDKPDFJJ_02583 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDKPDFJJ_02584 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HDKPDFJJ_02585 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HDKPDFJJ_02586 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HDKPDFJJ_02587 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HDKPDFJJ_02588 1.5e-43 abrB K of stationary sporulation gene expression
HDKPDFJJ_02589 1.7e-182 mreB D Rod-share determining protein MreBH
HDKPDFJJ_02590 1.1e-12 S Uncharacterized protein YkpC
HDKPDFJJ_02591 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HDKPDFJJ_02592 2.6e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDKPDFJJ_02593 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HDKPDFJJ_02594 8.1e-39 ykoA
HDKPDFJJ_02595 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HDKPDFJJ_02596 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HDKPDFJJ_02597 5.3e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HDKPDFJJ_02598 3.1e-136 fruR K Transcriptional regulator
HDKPDFJJ_02599 4.7e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HDKPDFJJ_02600 9.4e-124 macB V ABC transporter, ATP-binding protein
HDKPDFJJ_02601 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDKPDFJJ_02602 3.6e-115 yknW S Yip1 domain
HDKPDFJJ_02603 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HDKPDFJJ_02604 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HDKPDFJJ_02605 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HDKPDFJJ_02606 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HDKPDFJJ_02607 2.1e-91 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HDKPDFJJ_02608 2.6e-244 moeA 2.10.1.1 H molybdopterin
HDKPDFJJ_02609 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HDKPDFJJ_02610 1.1e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HDKPDFJJ_02611 4.2e-146 yknT
HDKPDFJJ_02612 5.8e-95 rok K Repressor of ComK
HDKPDFJJ_02613 1.4e-80 ykuV CO thiol-disulfide
HDKPDFJJ_02614 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HDKPDFJJ_02615 8.8e-142 ykuT M Mechanosensitive ion channel
HDKPDFJJ_02616 9e-37 ykuS S Belongs to the UPF0180 family
HDKPDFJJ_02617 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDKPDFJJ_02618 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDKPDFJJ_02619 4.3e-77 fld C Flavodoxin
HDKPDFJJ_02620 8.8e-175 ykuO
HDKPDFJJ_02621 2.9e-84 fld C Flavodoxin domain
HDKPDFJJ_02622 3.5e-168 ccpC K Transcriptional regulator
HDKPDFJJ_02623 1.6e-76 ykuL S CBS domain
HDKPDFJJ_02624 3.9e-27 ykzF S Antirepressor AbbA
HDKPDFJJ_02625 4.4e-94 ykuK S Ribonuclease H-like
HDKPDFJJ_02626 3.9e-37 ykuJ S protein conserved in bacteria
HDKPDFJJ_02627 5.2e-234 ykuI T Diguanylate phosphodiesterase
HDKPDFJJ_02628 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDKPDFJJ_02629 4.7e-165 ykuE S Metallophosphoesterase
HDKPDFJJ_02630 1.8e-87 ykuD S protein conserved in bacteria
HDKPDFJJ_02631 2.8e-238 ykuC EGP Major facilitator Superfamily
HDKPDFJJ_02632 4.9e-84 ykyB S YkyB-like protein
HDKPDFJJ_02633 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HDKPDFJJ_02634 2.2e-15
HDKPDFJJ_02635 6.3e-221 patA 2.6.1.1 E Aminotransferase
HDKPDFJJ_02636 0.0 pilS 2.7.13.3 T Histidine kinase
HDKPDFJJ_02637 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HDKPDFJJ_02638 1.8e-123 ykwD J protein with SCP PR1 domains
HDKPDFJJ_02639 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HDKPDFJJ_02640 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HDKPDFJJ_02641 1.3e-255 mcpC NT chemotaxis protein
HDKPDFJJ_02642 2.7e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDKPDFJJ_02643 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
HDKPDFJJ_02644 7.2e-39 splA S Transcriptional regulator
HDKPDFJJ_02645 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDKPDFJJ_02646 2.1e-39 ptsH G phosphocarrier protein HPr
HDKPDFJJ_02647 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDKPDFJJ_02648 7.6e-128 glcT K antiterminator
HDKPDFJJ_02650 8.3e-179 ykvZ 5.1.1.1 K Transcriptional regulator
HDKPDFJJ_02651 2.5e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HDKPDFJJ_02652 2.3e-09
HDKPDFJJ_02653 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HDKPDFJJ_02654 4.9e-90 stoA CO thiol-disulfide
HDKPDFJJ_02655 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDKPDFJJ_02656 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
HDKPDFJJ_02657 2.8e-28
HDKPDFJJ_02658 6e-25 ykvS S protein conserved in bacteria
HDKPDFJJ_02659 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HDKPDFJJ_02660 5.3e-162 G Glycosyl hydrolases family 18
HDKPDFJJ_02661 3.5e-35 3.5.1.104 M LysM domain
HDKPDFJJ_02662 1.2e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
HDKPDFJJ_02663 7e-133 IQ Enoyl-(Acyl carrier protein) reductase
HDKPDFJJ_02664 2.2e-60 ykvN K HxlR-like helix-turn-helix
HDKPDFJJ_02665 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HDKPDFJJ_02666 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HDKPDFJJ_02667 1.8e-80 queD 4.1.2.50, 4.2.3.12 H synthase
HDKPDFJJ_02668 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HDKPDFJJ_02669 3.3e-181 ykvI S membrane
HDKPDFJJ_02670 0.0 clpE O Belongs to the ClpA ClpB family
HDKPDFJJ_02671 1e-137 motA N flagellar motor
HDKPDFJJ_02672 2.5e-125 motB N Flagellar motor protein
HDKPDFJJ_02673 1.3e-75 ykvE K transcriptional
HDKPDFJJ_02674 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HDKPDFJJ_02675 1.8e-64 eag
HDKPDFJJ_02676 7.5e-10 S Spo0E like sporulation regulatory protein
HDKPDFJJ_02677 1.1e-50 XK27_09985 S Protein of unknown function (DUF1232)
HDKPDFJJ_02678 5.4e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HDKPDFJJ_02679 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HDKPDFJJ_02680 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HDKPDFJJ_02681 1.2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HDKPDFJJ_02682 5.2e-231 mtnE 2.6.1.83 E Aminotransferase
HDKPDFJJ_02683 1.7e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HDKPDFJJ_02684 3.7e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HDKPDFJJ_02685 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HDKPDFJJ_02687 5.9e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDKPDFJJ_02688 0.0 kinE 2.7.13.3 T Histidine kinase
HDKPDFJJ_02689 3.2e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HDKPDFJJ_02690 1.4e-18 ykzE
HDKPDFJJ_02691 1.2e-10 ydfR S Protein of unknown function (DUF421)
HDKPDFJJ_02692 6.3e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HDKPDFJJ_02693 1.7e-154 htpX O Belongs to the peptidase M48B family
HDKPDFJJ_02694 1.5e-124 ykrK S Domain of unknown function (DUF1836)
HDKPDFJJ_02695 1.9e-26 sspD S small acid-soluble spore protein
HDKPDFJJ_02696 6.7e-111 rsgI S Anti-sigma factor N-terminus
HDKPDFJJ_02697 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDKPDFJJ_02698 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HDKPDFJJ_02699 5.4e-110 ykoX S membrane-associated protein
HDKPDFJJ_02700 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HDKPDFJJ_02701 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HDKPDFJJ_02702 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HDKPDFJJ_02703 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDKPDFJJ_02704 0.0 ykoS
HDKPDFJJ_02705 1e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HDKPDFJJ_02706 3.7e-99 ykoP G polysaccharide deacetylase
HDKPDFJJ_02707 1.2e-165 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HDKPDFJJ_02708 9.3e-33 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HDKPDFJJ_02709 1.3e-81 mhqR K transcriptional
HDKPDFJJ_02710 6.9e-26 ykoL
HDKPDFJJ_02711 5.9e-18
HDKPDFJJ_02712 1.4e-53 tnrA K transcriptional
HDKPDFJJ_02713 2.2e-222 mgtE P Acts as a magnesium transporter
HDKPDFJJ_02716 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
HDKPDFJJ_02717 1.2e-110 ykoI S Peptidase propeptide and YPEB domain
HDKPDFJJ_02718 2.4e-240 ykoH 2.7.13.3 T Histidine kinase
HDKPDFJJ_02719 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_02720 1.8e-110 ykoF S YKOF-related Family
HDKPDFJJ_02721 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
HDKPDFJJ_02722 1.2e-305 P ABC transporter, ATP-binding protein
HDKPDFJJ_02723 4.5e-135 ykoC P Cobalt transport protein
HDKPDFJJ_02724 2.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDKPDFJJ_02725 5.5e-175 isp O Belongs to the peptidase S8 family
HDKPDFJJ_02726 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HDKPDFJJ_02727 1.4e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HDKPDFJJ_02728 8.4e-72 ohrB O Organic hydroperoxide resistance protein
HDKPDFJJ_02729 4.4e-74 ohrR K COG1846 Transcriptional regulators
HDKPDFJJ_02730 4.8e-70 ohrA O Organic hydroperoxide resistance protein
HDKPDFJJ_02731 4.5e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDKPDFJJ_02732 7.4e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDKPDFJJ_02733 5.6e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HDKPDFJJ_02734 9.1e-50 ykkD P Multidrug resistance protein
HDKPDFJJ_02735 1.1e-53 ykkC P Multidrug resistance protein
HDKPDFJJ_02736 9.9e-94 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HDKPDFJJ_02737 2.6e-97 ykkA S Protein of unknown function (DUF664)
HDKPDFJJ_02738 3.9e-128 ykjA S Protein of unknown function (DUF421)
HDKPDFJJ_02739 1.5e-09
HDKPDFJJ_02740 2.8e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HDKPDFJJ_02741 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HDKPDFJJ_02742 9.4e-158 ykgA E Amidinotransferase
HDKPDFJJ_02743 1.4e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
HDKPDFJJ_02744 2.6e-183 ykfD E Belongs to the ABC transporter superfamily
HDKPDFJJ_02745 1e-167 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HDKPDFJJ_02746 9.8e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HDKPDFJJ_02747 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HDKPDFJJ_02749 0.0 dppE E ABC transporter substrate-binding protein
HDKPDFJJ_02750 1e-187 dppD P Belongs to the ABC transporter superfamily
HDKPDFJJ_02751 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDKPDFJJ_02752 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDKPDFJJ_02753 5.1e-153 dppA E D-aminopeptidase
HDKPDFJJ_02754 9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HDKPDFJJ_02755 4.4e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HDKPDFJJ_02756 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDKPDFJJ_02757 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDKPDFJJ_02759 6.1e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HDKPDFJJ_02760 6.1e-241 steT E amino acid
HDKPDFJJ_02761 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HDKPDFJJ_02762 5.8e-175 pit P phosphate transporter
HDKPDFJJ_02763 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HDKPDFJJ_02764 6.7e-23 spoIISB S Stage II sporulation protein SB
HDKPDFJJ_02765 1.3e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HDKPDFJJ_02766 9.3e-40 xhlB S SPP1 phage holin
HDKPDFJJ_02767 2.8e-39 xhlA S Haemolysin XhlA
HDKPDFJJ_02768 2.8e-154 xepA
HDKPDFJJ_02769 2.1e-21 xkdX
HDKPDFJJ_02770 2.2e-43 xkdW S XkdW protein
HDKPDFJJ_02771 8e-178
HDKPDFJJ_02772 8.7e-41
HDKPDFJJ_02773 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HDKPDFJJ_02774 3e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HDKPDFJJ_02775 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HDKPDFJJ_02776 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HDKPDFJJ_02777 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HDKPDFJJ_02778 2.7e-118 xkdP S Lysin motif
HDKPDFJJ_02779 6.3e-227 xkdO L Transglycosylase SLT domain
HDKPDFJJ_02780 3.4e-10 xkdO L Transglycosylase SLT domain
HDKPDFJJ_02781 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
HDKPDFJJ_02782 1e-75 xkdM S Phage tail tube protein
HDKPDFJJ_02783 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HDKPDFJJ_02784 9.3e-77 xkdJ
HDKPDFJJ_02785 1.1e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
HDKPDFJJ_02786 7.3e-64 yqbH S Domain of unknown function (DUF3599)
HDKPDFJJ_02787 3.3e-62 yqbG S Protein of unknown function (DUF3199)
HDKPDFJJ_02788 1.7e-168 xkdG S Phage capsid family
HDKPDFJJ_02789 7.7e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HDKPDFJJ_02790 4.6e-285 yqbA S portal protein
HDKPDFJJ_02791 1.4e-253 xtmB S phage terminase, large subunit
HDKPDFJJ_02792 5.3e-139 xtmA L phage terminase small subunit
HDKPDFJJ_02793 4.5e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HDKPDFJJ_02794 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HDKPDFJJ_02797 9.2e-118 xkdC L Bacterial dnaA protein
HDKPDFJJ_02798 5e-156 xkdB K sequence-specific DNA binding
HDKPDFJJ_02800 9.2e-56 xre K Helix-turn-helix XRE-family like proteins
HDKPDFJJ_02801 1e-110 xkdA E IrrE N-terminal-like domain
HDKPDFJJ_02802 4.4e-160 ydbD P Catalase
HDKPDFJJ_02803 7.9e-111 yjqB S Pfam:DUF867
HDKPDFJJ_02804 6.1e-61 yjqA S Bacterial PH domain
HDKPDFJJ_02805 1.6e-161 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HDKPDFJJ_02806 1.6e-39 S YCII-related domain
HDKPDFJJ_02808 1e-212 S response regulator aspartate phosphatase
HDKPDFJJ_02809 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HDKPDFJJ_02810 2.3e-78 yjoA S DinB family
HDKPDFJJ_02811 7.4e-130 MA20_18170 S membrane transporter protein
HDKPDFJJ_02812 2.5e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HDKPDFJJ_02813 9.2e-283 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HDKPDFJJ_02814 6.8e-184 exuR K transcriptional
HDKPDFJJ_02815 4.1e-226 exuT G Sugar (and other) transporter
HDKPDFJJ_02816 5.2e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDKPDFJJ_02817 1.1e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HDKPDFJJ_02818 1.3e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HDKPDFJJ_02819 1.6e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HDKPDFJJ_02820 1.6e-247 yjmB G symporter YjmB
HDKPDFJJ_02821 3.3e-277 uxaC 5.3.1.12 G glucuronate isomerase
HDKPDFJJ_02822 8.5e-218 yjlD 1.6.99.3 C NADH dehydrogenase
HDKPDFJJ_02823 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HDKPDFJJ_02824 3.4e-91 yjlB S Cupin domain
HDKPDFJJ_02825 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HDKPDFJJ_02826 1.9e-122 ybbM S transport system, permease component
HDKPDFJJ_02827 7.3e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HDKPDFJJ_02828 8.2e-30
HDKPDFJJ_02829 1.1e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HDKPDFJJ_02830 8.9e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HDKPDFJJ_02832 2.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HDKPDFJJ_02833 2e-10 S Domain of unknown function (DUF4352)
HDKPDFJJ_02834 3.7e-94 yjgD S Protein of unknown function (DUF1641)
HDKPDFJJ_02835 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HDKPDFJJ_02836 1.7e-102 yjgB S Domain of unknown function (DUF4309)
HDKPDFJJ_02837 4.9e-34 T PhoQ Sensor
HDKPDFJJ_02838 2.1e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
HDKPDFJJ_02839 2.3e-20 yjfB S Putative motility protein
HDKPDFJJ_02840 1.8e-81 S Protein of unknown function (DUF2690)
HDKPDFJJ_02841 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
HDKPDFJJ_02843 1.6e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HDKPDFJJ_02844 1.5e-50 yjdJ S Domain of unknown function (DUF4306)
HDKPDFJJ_02845 7.1e-29 S Domain of unknown function (DUF4177)
HDKPDFJJ_02846 2.2e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDKPDFJJ_02848 3.4e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HDKPDFJJ_02849 3e-45 yjdF S Protein of unknown function (DUF2992)
HDKPDFJJ_02850 3.1e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDKPDFJJ_02851 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HDKPDFJJ_02852 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HDKPDFJJ_02854 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
HDKPDFJJ_02855 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
HDKPDFJJ_02856 6.2e-130 S response regulator aspartate phosphatase
HDKPDFJJ_02859 1.9e-20
HDKPDFJJ_02860 3.6e-234 M nucleic acid phosphodiester bond hydrolysis
HDKPDFJJ_02861 1.3e-48
HDKPDFJJ_02863 9.5e-209 yjcL S Protein of unknown function (DUF819)
HDKPDFJJ_02864 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
HDKPDFJJ_02865 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HDKPDFJJ_02866 7.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HDKPDFJJ_02867 3.2e-135 yjcH P COG2382 Enterochelin esterase and related enzymes
HDKPDFJJ_02868 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HDKPDFJJ_02869 1.1e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDKPDFJJ_02870 1.7e-38
HDKPDFJJ_02871 0.0 yjcD 3.6.4.12 L DNA helicase
HDKPDFJJ_02872 2.9e-38 spoVIF S Stage VI sporulation protein F
HDKPDFJJ_02875 4.3e-56 yjcA S Protein of unknown function (DUF1360)
HDKPDFJJ_02876 2.3e-55 cotV S Spore Coat Protein X and V domain
HDKPDFJJ_02877 8.5e-32 cotW
HDKPDFJJ_02878 6.4e-77 cotX S Spore Coat Protein X and V domain
HDKPDFJJ_02879 3.4e-96 cotY S Spore coat protein Z
HDKPDFJJ_02880 5.2e-83 cotZ S Spore coat protein
HDKPDFJJ_02881 1.4e-52 yjbX S Spore coat protein
HDKPDFJJ_02882 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HDKPDFJJ_02883 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HDKPDFJJ_02884 8.1e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HDKPDFJJ_02885 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HDKPDFJJ_02886 6.7e-30 thiS H thiamine diphosphate biosynthetic process
HDKPDFJJ_02887 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
HDKPDFJJ_02888 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HDKPDFJJ_02889 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HDKPDFJJ_02890 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDKPDFJJ_02891 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HDKPDFJJ_02892 6.8e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDKPDFJJ_02893 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDKPDFJJ_02894 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HDKPDFJJ_02895 2.7e-61 yjbL S Belongs to the UPF0738 family
HDKPDFJJ_02896 4.1e-101 yjbK S protein conserved in bacteria
HDKPDFJJ_02897 5.1e-88 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HDKPDFJJ_02898 3.7e-72 yjbI S Bacterial-like globin
HDKPDFJJ_02899 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HDKPDFJJ_02900 1.8e-20
HDKPDFJJ_02901 0.0 pepF E oligoendopeptidase F
HDKPDFJJ_02902 4.4e-219 yjbF S Competence protein
HDKPDFJJ_02903 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HDKPDFJJ_02904 6e-112 yjbE P Integral membrane protein TerC family
HDKPDFJJ_02905 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDKPDFJJ_02906 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDKPDFJJ_02907 5.3e-210 yjbB EGP Major Facilitator Superfamily
HDKPDFJJ_02908 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HDKPDFJJ_02909 1.5e-197 oppD P Belongs to the ABC transporter superfamily
HDKPDFJJ_02910 1e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDKPDFJJ_02911 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDKPDFJJ_02912 0.0 oppA E ABC transporter substrate-binding protein
HDKPDFJJ_02913 4e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HDKPDFJJ_02914 5e-147 yjbA S Belongs to the UPF0736 family
HDKPDFJJ_02915 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDKPDFJJ_02916 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDKPDFJJ_02917 3.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HDKPDFJJ_02918 4.7e-185 appF E Belongs to the ABC transporter superfamily
HDKPDFJJ_02919 1.8e-184 appD P Belongs to the ABC transporter superfamily
HDKPDFJJ_02920 2.5e-149 yjaZ O Zn-dependent protease
HDKPDFJJ_02921 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDKPDFJJ_02922 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDKPDFJJ_02923 3.9e-10 yjzB
HDKPDFJJ_02924 7.3e-26 comZ S ComZ
HDKPDFJJ_02925 2.5e-183 med S Transcriptional activator protein med
HDKPDFJJ_02926 6.9e-101 yjaV
HDKPDFJJ_02927 3.1e-141 yjaU I carboxylic ester hydrolase activity
HDKPDFJJ_02928 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HDKPDFJJ_02929 9.5e-28 yjzC S YjzC-like protein
HDKPDFJJ_02930 3.3e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDKPDFJJ_02931 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HDKPDFJJ_02932 1.4e-203 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDKPDFJJ_02933 3.2e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HDKPDFJJ_02934 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HDKPDFJJ_02935 2.2e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDKPDFJJ_02936 3.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDKPDFJJ_02937 1.7e-88 norB G Major Facilitator Superfamily
HDKPDFJJ_02938 1.7e-268 yitY C D-arabinono-1,4-lactone oxidase
HDKPDFJJ_02939 1.5e-22 pilT S Proteolipid membrane potential modulator
HDKPDFJJ_02940 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HDKPDFJJ_02941 1.7e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HDKPDFJJ_02942 5.4e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HDKPDFJJ_02944 1.2e-17 S Protein of unknown function (DUF3813)
HDKPDFJJ_02945 5e-73 ipi S Intracellular proteinase inhibitor
HDKPDFJJ_02946 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HDKPDFJJ_02947 9.3e-158 yitS S protein conserved in bacteria
HDKPDFJJ_02948 3.9e-306 nprB 3.4.24.28 E Peptidase M4
HDKPDFJJ_02949 1.4e-44 yitR S Domain of unknown function (DUF3784)
HDKPDFJJ_02950 1.3e-94
HDKPDFJJ_02951 1.5e-58 K Transcriptional regulator PadR-like family
HDKPDFJJ_02952 1.5e-97 S Sporulation delaying protein SdpA
HDKPDFJJ_02953 8.9e-170
HDKPDFJJ_02954 8.5e-94
HDKPDFJJ_02955 3.4e-160 cvfB S protein conserved in bacteria
HDKPDFJJ_02956 8.6e-55 yajQ S Belongs to the UPF0234 family
HDKPDFJJ_02957 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HDKPDFJJ_02958 9.2e-72 yjcF S Acetyltransferase (GNAT) domain
HDKPDFJJ_02959 7.9e-157 yitH K Acetyltransferase (GNAT) domain
HDKPDFJJ_02960 1.3e-227 yitG EGP Major facilitator Superfamily
HDKPDFJJ_02961 3.5e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HDKPDFJJ_02962 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDKPDFJJ_02963 3.5e-140 yitD 4.4.1.19 S synthase
HDKPDFJJ_02964 1.2e-118 comB 3.1.3.71 H Belongs to the ComB family
HDKPDFJJ_02965 1.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HDKPDFJJ_02966 3.3e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HDKPDFJJ_02967 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HDKPDFJJ_02968 5.9e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HDKPDFJJ_02969 1.2e-35 mcbG S Pentapeptide repeats (9 copies)
HDKPDFJJ_02970 5.6e-272 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDKPDFJJ_02971 6e-106 argO S Lysine exporter protein LysE YggA
HDKPDFJJ_02972 1.8e-92 yisT S DinB family
HDKPDFJJ_02973 2.3e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HDKPDFJJ_02974 2e-183 purR K helix_turn _helix lactose operon repressor
HDKPDFJJ_02975 3.5e-160 yisR K Transcriptional regulator
HDKPDFJJ_02976 4e-243 yisQ V Mate efflux family protein
HDKPDFJJ_02977 3.9e-113 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HDKPDFJJ_02978 0.0 asnO 6.3.5.4 E Asparagine synthase
HDKPDFJJ_02979 1.8e-101 yisN S Protein of unknown function (DUF2777)
HDKPDFJJ_02980 0.0 wprA O Belongs to the peptidase S8 family
HDKPDFJJ_02981 3e-57 yisL S UPF0344 protein
HDKPDFJJ_02982 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HDKPDFJJ_02983 1.1e-172 cotH M Spore Coat
HDKPDFJJ_02984 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HDKPDFJJ_02985 1.9e-33 gerPA S Spore germination protein
HDKPDFJJ_02986 1.2e-33 gerPB S cell differentiation
HDKPDFJJ_02987 5.3e-54 gerPC S Spore germination protein
HDKPDFJJ_02988 1.1e-23 gerPD S Spore germination protein
HDKPDFJJ_02989 5.3e-63 gerPE S Spore germination protein GerPE
HDKPDFJJ_02990 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HDKPDFJJ_02991 2.5e-49 yisB V COG1403 Restriction endonuclease
HDKPDFJJ_02992 0.0 sbcC L COG0419 ATPase involved in DNA repair
HDKPDFJJ_02993 4.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDKPDFJJ_02994 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HDKPDFJJ_02995 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HDKPDFJJ_02996 2.2e-78 yhjR S Rubrerythrin
HDKPDFJJ_02997 3e-32 yhjQ C COG1145 Ferredoxin
HDKPDFJJ_02998 3.7e-204 S Sugar transport-related sRNA regulator N-term
HDKPDFJJ_02999 2.1e-117 S Sugar transport-related sRNA regulator N-term
HDKPDFJJ_03000 4.9e-213 EGP Transmembrane secretion effector
HDKPDFJJ_03001 4.2e-201 abrB S membrane
HDKPDFJJ_03002 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
HDKPDFJJ_03003 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HDKPDFJJ_03004 7.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HDKPDFJJ_03005 5.5e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HDKPDFJJ_03006 1.3e-213 glcP G Major Facilitator Superfamily
HDKPDFJJ_03009 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HDKPDFJJ_03010 4.5e-280 yhjG CH FAD binding domain
HDKPDFJJ_03011 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HDKPDFJJ_03012 5.9e-109 yhjE S SNARE associated Golgi protein
HDKPDFJJ_03013 6.7e-60 yhjD
HDKPDFJJ_03014 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HDKPDFJJ_03015 2e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDKPDFJJ_03016 3.9e-41 yhjA S Excalibur calcium-binding domain
HDKPDFJJ_03017 1.4e-167 IQ Enoyl-(Acyl carrier protein) reductase
HDKPDFJJ_03018 4.2e-109 comK K Competence transcription factor
HDKPDFJJ_03019 1.3e-32 yhzC S IDEAL
HDKPDFJJ_03020 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDKPDFJJ_03021 8e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HDKPDFJJ_03022 3.1e-181 hemAT NT chemotaxis protein
HDKPDFJJ_03023 1.9e-90 bioY S BioY family
HDKPDFJJ_03024 1.9e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HDKPDFJJ_03025 3.2e-195 vraB 2.3.1.9 I Belongs to the thiolase family
HDKPDFJJ_03026 5.5e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HDKPDFJJ_03027 4.3e-159 yfmC M Periplasmic binding protein
HDKPDFJJ_03028 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HDKPDFJJ_03029 1.6e-76 VY92_01935 K acetyltransferase
HDKPDFJJ_03030 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HDKPDFJJ_03031 1.2e-241 yhfN 3.4.24.84 O Peptidase M48
HDKPDFJJ_03032 1.3e-64 yhfM
HDKPDFJJ_03033 5.7e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HDKPDFJJ_03034 1.4e-110 yhfK GM NmrA-like family
HDKPDFJJ_03035 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HDKPDFJJ_03036 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HDKPDFJJ_03037 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDKPDFJJ_03038 1.1e-71 3.4.13.21 S ASCH
HDKPDFJJ_03039 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HDKPDFJJ_03040 2.2e-137 yhfC S Putative membrane peptidase family (DUF2324)
HDKPDFJJ_03041 8.7e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDKPDFJJ_03042 2e-223 yhgE S YhgE Pip N-terminal domain protein
HDKPDFJJ_03043 5.4e-101 yhgD K Transcriptional regulator
HDKPDFJJ_03044 5e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HDKPDFJJ_03045 2.3e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HDKPDFJJ_03046 2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HDKPDFJJ_03047 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDKPDFJJ_03048 7.1e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HDKPDFJJ_03049 1.2e-30 1.15.1.2 C Rubrerythrin
HDKPDFJJ_03050 3.5e-231 yhfA C membrane
HDKPDFJJ_03051 2e-227 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HDKPDFJJ_03052 3.4e-113 ecsC S EcsC protein family
HDKPDFJJ_03053 5e-213 ecsB U ABC transporter
HDKPDFJJ_03054 1.8e-136 ecsA V transporter (ATP-binding protein)
HDKPDFJJ_03055 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HDKPDFJJ_03056 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDKPDFJJ_03057 3.6e-80 trpP S Tryptophan transporter TrpP
HDKPDFJJ_03058 7e-39 yhaH S YtxH-like protein
HDKPDFJJ_03059 1e-113 hpr K Negative regulator of protease production and sporulation
HDKPDFJJ_03060 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HDKPDFJJ_03061 1.1e-89 yhaK S Putative zincin peptidase
HDKPDFJJ_03062 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDKPDFJJ_03063 1.6e-21 yhaL S Sporulation protein YhaL
HDKPDFJJ_03064 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HDKPDFJJ_03065 0.0 yhaN L AAA domain
HDKPDFJJ_03066 2.6e-225 yhaO L DNA repair exonuclease
HDKPDFJJ_03067 9.4e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HDKPDFJJ_03068 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HDKPDFJJ_03069 7e-26 S YhzD-like protein
HDKPDFJJ_03070 2.7e-130 yhaR 5.3.3.18 I enoyl-CoA hydratase
HDKPDFJJ_03072 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HDKPDFJJ_03073 1.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
HDKPDFJJ_03074 2.5e-291 hemZ H coproporphyrinogen III oxidase
HDKPDFJJ_03075 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HDKPDFJJ_03076 3e-201 yhaZ L DNA alkylation repair enzyme
HDKPDFJJ_03077 9.5e-48 yheA S Belongs to the UPF0342 family
HDKPDFJJ_03078 2.2e-202 yheB S Belongs to the UPF0754 family
HDKPDFJJ_03079 4.3e-216 yheC HJ YheC/D like ATP-grasp
HDKPDFJJ_03080 9.7e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HDKPDFJJ_03081 1.3e-36 yheE S Family of unknown function (DUF5342)
HDKPDFJJ_03082 6.3e-28 sspB S spore protein
HDKPDFJJ_03083 2.6e-109 yheG GM NAD(P)H-binding
HDKPDFJJ_03084 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HDKPDFJJ_03085 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HDKPDFJJ_03086 5.2e-84 nhaX T Belongs to the universal stress protein A family
HDKPDFJJ_03087 8.6e-230 nhaC C Na H antiporter
HDKPDFJJ_03088 6.9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HDKPDFJJ_03089 6.3e-146 yheN G deacetylase
HDKPDFJJ_03090 7.9e-137 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HDKPDFJJ_03091 1.4e-182 yhdY M Mechanosensitive ion channel
HDKPDFJJ_03093 8.9e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HDKPDFJJ_03094 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDKPDFJJ_03095 7.1e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDKPDFJJ_03096 1.4e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HDKPDFJJ_03097 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
HDKPDFJJ_03098 4.7e-74 cueR K transcriptional
HDKPDFJJ_03099 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HDKPDFJJ_03100 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HDKPDFJJ_03101 4.4e-191 yhdN C Aldo keto reductase
HDKPDFJJ_03102 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HDKPDFJJ_03103 6.6e-201 yhdL S Sigma factor regulator N-terminal
HDKPDFJJ_03104 8.1e-45 yhdK S Sigma-M inhibitor protein
HDKPDFJJ_03105 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDKPDFJJ_03106 5.1e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDKPDFJJ_03107 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HDKPDFJJ_03108 3.4e-250 yhdG E amino acid
HDKPDFJJ_03109 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDKPDFJJ_03110 4.1e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
HDKPDFJJ_03111 3.8e-162 citR K Transcriptional regulator
HDKPDFJJ_03112 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HDKPDFJJ_03113 9.2e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HDKPDFJJ_03114 3.7e-276 ycgB S Stage V sporulation protein R
HDKPDFJJ_03115 1.3e-237 ygxB M Conserved TM helix
HDKPDFJJ_03116 1e-75 nsrR K Transcriptional regulator
HDKPDFJJ_03117 1.9e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HDKPDFJJ_03118 2e-52 yhdC S Protein of unknown function (DUF3889)
HDKPDFJJ_03119 6.1e-38 yhdB S YhdB-like protein
HDKPDFJJ_03120 1.4e-82 azr 1.7.1.6 S NADPH-dependent FMN reductase
HDKPDFJJ_03121 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDKPDFJJ_03122 1.5e-211 yhcY 2.7.13.3 T Histidine kinase
HDKPDFJJ_03123 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HDKPDFJJ_03124 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HDKPDFJJ_03125 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDKPDFJJ_03126 5.7e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HDKPDFJJ_03127 9.9e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HDKPDFJJ_03128 3e-259 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDKPDFJJ_03129 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HDKPDFJJ_03130 1e-119 yhcW 5.4.2.6 S hydrolase
HDKPDFJJ_03131 9.9e-68 yhcV S COG0517 FOG CBS domain
HDKPDFJJ_03132 9.3e-68 yhcU S Family of unknown function (DUF5365)
HDKPDFJJ_03133 2.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDKPDFJJ_03134 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HDKPDFJJ_03135 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HDKPDFJJ_03136 5.2e-100 yhcQ M Spore coat protein
HDKPDFJJ_03137 2.5e-167 yhcP
HDKPDFJJ_03138 1.7e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HDKPDFJJ_03139 1.1e-40 yhcM
HDKPDFJJ_03140 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDKPDFJJ_03141 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HDKPDFJJ_03142 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
HDKPDFJJ_03143 1e-30 cspB K Cold-shock protein
HDKPDFJJ_03144 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HDKPDFJJ_03145 2.2e-165 yhcH V ABC transporter, ATP-binding protein
HDKPDFJJ_03146 1.5e-121 yhcG V ABC transporter, ATP-binding protein
HDKPDFJJ_03147 7.3e-59 yhcF K Transcriptional regulator
HDKPDFJJ_03148 3.5e-55
HDKPDFJJ_03149 2.3e-36 yhcC
HDKPDFJJ_03150 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HDKPDFJJ_03151 3.1e-271 yhcA EGP Major facilitator Superfamily
HDKPDFJJ_03152 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HDKPDFJJ_03153 2.2e-76 yhbI K DNA-binding transcription factor activity
HDKPDFJJ_03154 2.5e-225 yhbH S Belongs to the UPF0229 family
HDKPDFJJ_03155 0.0 prkA T Ser protein kinase
HDKPDFJJ_03156 6.1e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HDKPDFJJ_03157 1.4e-58 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HDKPDFJJ_03158 6e-109 yhbD K Protein of unknown function (DUF4004)
HDKPDFJJ_03159 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDKPDFJJ_03160 4.8e-176 yhbB S Putative amidase domain
HDKPDFJJ_03161 3.5e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HDKPDFJJ_03162 2.3e-113 yhzB S B3/4 domain
HDKPDFJJ_03164 4.4e-29 K Transcriptional regulator
HDKPDFJJ_03165 1.7e-76 ygaO
HDKPDFJJ_03166 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDKPDFJJ_03168 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HDKPDFJJ_03169 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HDKPDFJJ_03170 8.1e-169 ssuA M Sulfonate ABC transporter
HDKPDFJJ_03171 1.5e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HDKPDFJJ_03172 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HDKPDFJJ_03174 1.1e-261 ygaK C Berberine and berberine like
HDKPDFJJ_03175 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HDKPDFJJ_03176 1.4e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HDKPDFJJ_03177 1.2e-26
HDKPDFJJ_03178 6.5e-142 spo0M S COG4326 Sporulation control protein
HDKPDFJJ_03181 4.6e-157 ydhU P Catalase
HDKPDFJJ_03182 6.4e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HDKPDFJJ_03183 1.3e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDKPDFJJ_03184 2.4e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HDKPDFJJ_03185 1.1e-132 ydhQ K UTRA
HDKPDFJJ_03186 9e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDKPDFJJ_03187 4.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDKPDFJJ_03188 5.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HDKPDFJJ_03189 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HDKPDFJJ_03190 4.6e-200 pbuE EGP Major facilitator Superfamily
HDKPDFJJ_03191 9.4e-98 ydhK M Protein of unknown function (DUF1541)
HDKPDFJJ_03192 1.3e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDKPDFJJ_03193 8.6e-84 K Acetyltransferase (GNAT) domain
HDKPDFJJ_03195 1.1e-67 frataxin S Domain of unknown function (DU1801)
HDKPDFJJ_03196 9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HDKPDFJJ_03197 5.1e-125
HDKPDFJJ_03198 1.3e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HDKPDFJJ_03199 9e-242 ydhD M Glycosyl hydrolase
HDKPDFJJ_03200 3.2e-121 ydhC K FCD
HDKPDFJJ_03201 1.2e-121 ydhB S membrane transporter protein
HDKPDFJJ_03202 2.2e-208 tcaB EGP Major facilitator Superfamily
HDKPDFJJ_03203 2.4e-69 ydgJ K Winged helix DNA-binding domain
HDKPDFJJ_03204 1e-113 drgA C nitroreductase
HDKPDFJJ_03205 0.0 ydgH S drug exporters of the RND superfamily
HDKPDFJJ_03206 1.5e-78 K helix_turn_helix multiple antibiotic resistance protein
HDKPDFJJ_03207 4.7e-88 dinB S DinB family
HDKPDFJJ_03208 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HDKPDFJJ_03209 9.8e-305 expZ S ABC transporter
HDKPDFJJ_03210 4.6e-82 yycN 2.3.1.128 K Acetyltransferase
HDKPDFJJ_03211 1.4e-51 S DoxX-like family
HDKPDFJJ_03212 7.6e-98 K Bacterial regulatory proteins, tetR family
HDKPDFJJ_03213 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HDKPDFJJ_03214 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
HDKPDFJJ_03215 3.2e-74 cotP O Belongs to the small heat shock protein (HSP20) family
HDKPDFJJ_03216 2.6e-121 ydfS S Protein of unknown function (DUF421)
HDKPDFJJ_03217 1.9e-99 ydfR S Protein of unknown function (DUF421)
HDKPDFJJ_03219 6.3e-29
HDKPDFJJ_03220 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HDKPDFJJ_03221 1.7e-54 traF CO Thioredoxin
HDKPDFJJ_03222 8.8e-63 mhqP S DoxX
HDKPDFJJ_03223 4.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HDKPDFJJ_03224 1.1e-110 ydfN C nitroreductase
HDKPDFJJ_03225 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDKPDFJJ_03226 9.2e-147 K Bacterial transcription activator, effector binding domain
HDKPDFJJ_03227 8.5e-117 S Protein of unknown function (DUF554)
HDKPDFJJ_03228 3.4e-174 S Alpha/beta hydrolase family
HDKPDFJJ_03229 0.0 ydfJ S drug exporters of the RND superfamily
HDKPDFJJ_03230 2.1e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDKPDFJJ_03231 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
HDKPDFJJ_03233 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HDKPDFJJ_03234 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HDKPDFJJ_03235 4.2e-115 ydfE S Flavin reductase like domain
HDKPDFJJ_03236 6.7e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDKPDFJJ_03237 2.2e-149 ydfC EG EamA-like transporter family
HDKPDFJJ_03238 1.8e-122 T Transcriptional regulatory protein, C terminal
HDKPDFJJ_03239 7.5e-224 T GHKL domain
HDKPDFJJ_03240 5.1e-159
HDKPDFJJ_03241 4.5e-122 nodB1 G deacetylase
HDKPDFJJ_03242 6.3e-149 lytR K Transcriptional regulator
HDKPDFJJ_03243 9.8e-146 ydfB J GNAT acetyltransferase
HDKPDFJJ_03244 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HDKPDFJJ_03245 2.4e-56 arsR K transcriptional
HDKPDFJJ_03246 3.2e-104 ydeS K Transcriptional regulator
HDKPDFJJ_03247 1.5e-193 ydeR EGP Major facilitator Superfamily
HDKPDFJJ_03248 1.4e-107 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HDKPDFJJ_03249 4.8e-69 ydeP K Transcriptional regulator
HDKPDFJJ_03250 1.6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HDKPDFJJ_03251 8.9e-56 K HxlR-like helix-turn-helix
HDKPDFJJ_03252 1.8e-104 ydeN S Serine hydrolase
HDKPDFJJ_03253 6e-73 maoC I N-terminal half of MaoC dehydratase
HDKPDFJJ_03254 2.4e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDKPDFJJ_03255 1.8e-153 ydeK EG -transporter
HDKPDFJJ_03256 3.4e-84 K Transcriptional regulator C-terminal region
HDKPDFJJ_03257 1.8e-14 ptsH G PTS HPr component phosphorylation site
HDKPDFJJ_03258 1.8e-100
HDKPDFJJ_03259 5.1e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HDKPDFJJ_03260 2.7e-45 ydeH
HDKPDFJJ_03261 5.5e-218 ydeG EGP Major facilitator superfamily
HDKPDFJJ_03262 6.2e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDKPDFJJ_03263 1.2e-163 ydeE K AraC family transcriptional regulator
HDKPDFJJ_03264 1.4e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HDKPDFJJ_03265 9.9e-163 rhaS5 K AraC-like ligand binding domain
HDKPDFJJ_03266 1.2e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HDKPDFJJ_03267 2.3e-78 carD K Transcription factor
HDKPDFJJ_03268 8.7e-30 cspL K Cold shock
HDKPDFJJ_03269 7.5e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HDKPDFJJ_03270 9.6e-40
HDKPDFJJ_03271 3.4e-33 K Helix-turn-helix XRE-family like proteins
HDKPDFJJ_03272 4.5e-15 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HDKPDFJJ_03273 5e-47 ydeH
HDKPDFJJ_03274 9e-208 msbA2 3.6.3.44 V ABC transporter
HDKPDFJJ_03275 9.8e-211 KLT Protein kinase domain
HDKPDFJJ_03281 3.1e-159 KLT Protein kinase domain
HDKPDFJJ_03293 3.4e-82 ydcK S Belongs to the SprT family
HDKPDFJJ_03294 0.0 yhgF K COG2183 Transcriptional accessory protein
HDKPDFJJ_03295 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HDKPDFJJ_03296 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HDKPDFJJ_03297 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HDKPDFJJ_03298 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
HDKPDFJJ_03299 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HDKPDFJJ_03300 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HDKPDFJJ_03301 5.2e-57 rsbS T antagonist
HDKPDFJJ_03302 1.3e-143 rsbR T Positive regulator of sigma-B
HDKPDFJJ_03303 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HDKPDFJJ_03304 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HDKPDFJJ_03305 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDKPDFJJ_03306 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HDKPDFJJ_03307 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDKPDFJJ_03308 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HDKPDFJJ_03309 8.6e-260 ydbT S Membrane
HDKPDFJJ_03310 2.1e-82 ydbS S Bacterial PH domain
HDKPDFJJ_03311 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDKPDFJJ_03312 1.6e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDKPDFJJ_03313 3.7e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDKPDFJJ_03314 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDKPDFJJ_03315 1.3e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDKPDFJJ_03316 2.2e-07 S Fur-regulated basic protein A
HDKPDFJJ_03317 1.1e-18 S Fur-regulated basic protein B
HDKPDFJJ_03318 6.3e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HDKPDFJJ_03319 2.7e-52 ydbL
HDKPDFJJ_03320 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HDKPDFJJ_03321 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
HDKPDFJJ_03322 4.4e-181 ydbI S AI-2E family transporter
HDKPDFJJ_03323 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDKPDFJJ_03324 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HDKPDFJJ_03325 8.1e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HDKPDFJJ_03326 1.3e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HDKPDFJJ_03327 2.3e-153 ydbD P Catalase
HDKPDFJJ_03328 1.8e-62 ydbC S Domain of unknown function (DUF4937
HDKPDFJJ_03329 2.6e-58 ydbB G Cupin domain
HDKPDFJJ_03331 1.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HDKPDFJJ_03332 6.3e-70 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HDKPDFJJ_03334 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HDKPDFJJ_03335 9.4e-40
HDKPDFJJ_03337 1.4e-72 sdpB S Protein conserved in bacteria
HDKPDFJJ_03338 1.8e-27
HDKPDFJJ_03340 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDKPDFJJ_03341 4.4e-43 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HDKPDFJJ_03342 0.0 ydaO E amino acid
HDKPDFJJ_03343 0.0 ydaN S Bacterial cellulose synthase subunit
HDKPDFJJ_03344 4.5e-233 ydaM M Glycosyl transferase family group 2
HDKPDFJJ_03345 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HDKPDFJJ_03346 2.5e-150 ydaK T Diguanylate cyclase, GGDEF domain
HDKPDFJJ_03347 4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HDKPDFJJ_03348 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDKPDFJJ_03349 2.5e-74 lrpC K Transcriptional regulator
HDKPDFJJ_03350 3.6e-45 ydzA EGP Major facilitator Superfamily
HDKPDFJJ_03351 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HDKPDFJJ_03352 6.8e-77 ydaG 1.4.3.5 S general stress protein
HDKPDFJJ_03353 6.1e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HDKPDFJJ_03354 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HDKPDFJJ_03355 4.5e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDKPDFJJ_03356 1.7e-97 ydaC Q Methyltransferase domain
HDKPDFJJ_03357 3e-292 ydaB IQ acyl-CoA ligase
HDKPDFJJ_03358 0.0 mtlR K transcriptional regulator, MtlR
HDKPDFJJ_03359 8.1e-176 ydhF S Oxidoreductase
HDKPDFJJ_03360 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HDKPDFJJ_03361 1.4e-49 yczJ S biosynthesis
HDKPDFJJ_03363 3.5e-117 ycsK E anatomical structure formation involved in morphogenesis
HDKPDFJJ_03364 2.7e-132 kipR K Transcriptional regulator
HDKPDFJJ_03365 3.1e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HDKPDFJJ_03366 1.4e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HDKPDFJJ_03367 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
HDKPDFJJ_03368 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HDKPDFJJ_03369 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
HDKPDFJJ_03370 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HDKPDFJJ_03372 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HDKPDFJJ_03373 3.7e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HDKPDFJJ_03374 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HDKPDFJJ_03376 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HDKPDFJJ_03377 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HDKPDFJJ_03378 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HDKPDFJJ_03379 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HDKPDFJJ_03380 3.4e-53
HDKPDFJJ_03381 4.7e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HDKPDFJJ_03382 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
HDKPDFJJ_03383 1.4e-99 ycnI S protein conserved in bacteria
HDKPDFJJ_03384 4.6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDKPDFJJ_03385 1.8e-148 glcU U Glucose uptake
HDKPDFJJ_03386 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDKPDFJJ_03387 2.8e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDKPDFJJ_03388 1.5e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDKPDFJJ_03389 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HDKPDFJJ_03390 1.6e-45 ycnE S Monooxygenase
HDKPDFJJ_03391 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HDKPDFJJ_03392 6.5e-154 ycnC K Transcriptional regulator
HDKPDFJJ_03393 1.6e-250 ycnB EGP Major facilitator Superfamily
HDKPDFJJ_03394 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HDKPDFJJ_03395 2.4e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HDKPDFJJ_03396 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_03397 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_03398 1.5e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
HDKPDFJJ_03402 1.6e-80 S aspartate phosphatase
HDKPDFJJ_03403 1.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HDKPDFJJ_03404 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_03405 1.3e-202 yclI V ABC transporter (permease) YclI
HDKPDFJJ_03406 7.3e-121 yclH P ABC transporter
HDKPDFJJ_03407 3e-196 gerKB F Spore germination protein
HDKPDFJJ_03408 1.6e-230 gerKC S spore germination
HDKPDFJJ_03409 7.5e-281 gerKA EG Spore germination protein
HDKPDFJJ_03411 3.2e-293 yclG M Pectate lyase superfamily protein
HDKPDFJJ_03412 1.3e-263 dtpT E amino acid peptide transporter
HDKPDFJJ_03413 7.1e-77 yclE 3.4.11.5 S Alpha beta hydrolase
HDKPDFJJ_03414 3.7e-41 yclE 3.4.11.5 S Alpha beta hydrolase
HDKPDFJJ_03415 6.6e-81 yclD
HDKPDFJJ_03416 4e-39 bsdD 4.1.1.61 S response to toxic substance
HDKPDFJJ_03417 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HDKPDFJJ_03418 3.2e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HDKPDFJJ_03419 1.9e-161 bsdA K LysR substrate binding domain
HDKPDFJJ_03420 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HDKPDFJJ_03421 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HDKPDFJJ_03422 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HDKPDFJJ_03423 9.7e-115 yczE S membrane
HDKPDFJJ_03424 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HDKPDFJJ_03425 1.7e-251 ycxD K GntR family transcriptional regulator
HDKPDFJJ_03426 1.7e-160 ycxC EG EamA-like transporter family
HDKPDFJJ_03427 3e-88 S YcxB-like protein
HDKPDFJJ_03428 3.7e-224 EGP Major Facilitator Superfamily
HDKPDFJJ_03429 5.7e-140 srfAD Q thioesterase
HDKPDFJJ_03430 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HDKPDFJJ_03431 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDKPDFJJ_03432 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDKPDFJJ_03433 1.3e-63 hxlR K transcriptional
HDKPDFJJ_03434 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HDKPDFJJ_03435 3.9e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HDKPDFJJ_03436 1.8e-184 tlpC 2.7.13.3 NT chemotaxis protein
HDKPDFJJ_03437 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
HDKPDFJJ_03438 1.1e-68 nin S Competence protein J (ComJ)
HDKPDFJJ_03439 1.5e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDKPDFJJ_03440 6e-121 S AAA domain
HDKPDFJJ_03441 9.3e-24
HDKPDFJJ_03442 4.1e-45 K MarR family
HDKPDFJJ_03443 7.8e-52 yckD S Protein of unknown function (DUF2680)
HDKPDFJJ_03444 3.1e-75 yckC S membrane
HDKPDFJJ_03446 1.7e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HDKPDFJJ_03447 1.2e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
HDKPDFJJ_03448 7.8e-227 yciC S GTPases (G3E family)
HDKPDFJJ_03449 5.1e-107 yciB M ErfK YbiS YcfS YnhG
HDKPDFJJ_03450 3.5e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HDKPDFJJ_03451 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
HDKPDFJJ_03452 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HDKPDFJJ_03453 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HDKPDFJJ_03454 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HDKPDFJJ_03455 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HDKPDFJJ_03456 2.1e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HDKPDFJJ_03457 6e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HDKPDFJJ_03458 3.2e-158 I alpha/beta hydrolase fold
HDKPDFJJ_03459 1.2e-139 ycgR S permeases
HDKPDFJJ_03460 1.3e-146 ycgQ S membrane
HDKPDFJJ_03461 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HDKPDFJJ_03462 5.9e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDKPDFJJ_03463 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HDKPDFJJ_03464 5.1e-170 ycgM E Proline dehydrogenase
HDKPDFJJ_03465 2.4e-144 ycgL S Predicted nucleotidyltransferase
HDKPDFJJ_03466 2.1e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HDKPDFJJ_03467 7.9e-177 oxyR3 K LysR substrate binding domain
HDKPDFJJ_03468 3.4e-143 yafE Q ubiE/COQ5 methyltransferase family
HDKPDFJJ_03469 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HDKPDFJJ_03471 2.3e-107 tmrB S AAA domain
HDKPDFJJ_03472 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDKPDFJJ_03473 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HDKPDFJJ_03474 1.8e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HDKPDFJJ_03475 1.3e-150 yqcI S YqcI/YcgG family
HDKPDFJJ_03476 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HDKPDFJJ_03477 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HDKPDFJJ_03478 8.7e-263 mdr EGP Major facilitator Superfamily
HDKPDFJJ_03479 4.7e-291 lctP C L-lactate permease
HDKPDFJJ_03480 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDKPDFJJ_03481 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HDKPDFJJ_03482 1.2e-80 ycgB
HDKPDFJJ_03483 1.6e-255 ycgA S Membrane
HDKPDFJJ_03484 5e-215 amhX S amidohydrolase
HDKPDFJJ_03485 1.2e-163 opuAC E glycine betaine
HDKPDFJJ_03486 1.3e-127 opuAB P glycine betaine
HDKPDFJJ_03487 4.3e-228 proV 3.6.3.32 E glycine betaine
HDKPDFJJ_03488 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDKPDFJJ_03489 2e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
HDKPDFJJ_03490 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
HDKPDFJJ_03491 2e-192 yceH P Belongs to the TelA family
HDKPDFJJ_03492 0.0 yceG S Putative component of 'biosynthetic module'
HDKPDFJJ_03493 6.3e-137 terC P Protein of unknown function (DUF475)
HDKPDFJJ_03494 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HDKPDFJJ_03495 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HDKPDFJJ_03496 1.1e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HDKPDFJJ_03497 5e-187 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDKPDFJJ_03498 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HDKPDFJJ_03499 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HDKPDFJJ_03500 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
HDKPDFJJ_03501 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HDKPDFJJ_03502 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
HDKPDFJJ_03503 1.2e-173 S response regulator aspartate phosphatase
HDKPDFJJ_03504 1.3e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
HDKPDFJJ_03505 2.6e-256 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HDKPDFJJ_03506 2.5e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HDKPDFJJ_03507 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HDKPDFJJ_03508 1.3e-173 yccK C Aldo keto reductase
HDKPDFJJ_03509 1e-199 natB CP ABC-2 family transporter protein
HDKPDFJJ_03510 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HDKPDFJJ_03511 1.1e-124 lytR_2 T LytTr DNA-binding domain
HDKPDFJJ_03512 3e-157 2.7.13.3 T GHKL domain
HDKPDFJJ_03513 2.8e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
HDKPDFJJ_03514 1.7e-58 S RDD family
HDKPDFJJ_03515 9.3e-102 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HDKPDFJJ_03516 2.6e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HDKPDFJJ_03517 7e-101 yxaF K Transcriptional regulator
HDKPDFJJ_03518 5.8e-229 lmrB EGP the major facilitator superfamily
HDKPDFJJ_03519 1.2e-200 ycbU E Selenocysteine lyase
HDKPDFJJ_03520 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HDKPDFJJ_03521 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDKPDFJJ_03522 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HDKPDFJJ_03523 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HDKPDFJJ_03524 9.5e-135 ycbR T vWA found in TerF C terminus
HDKPDFJJ_03525 2.2e-78 sleB 3.5.1.28 M Cell wall
HDKPDFJJ_03526 4.1e-52 ycbP S Protein of unknown function (DUF2512)
HDKPDFJJ_03527 2.4e-111 S ABC-2 family transporter protein
HDKPDFJJ_03528 5.9e-166 ycbN V ABC transporter, ATP-binding protein
HDKPDFJJ_03529 2.9e-168 T PhoQ Sensor
HDKPDFJJ_03530 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDKPDFJJ_03531 5.3e-170 eamA1 EG spore germination
HDKPDFJJ_03532 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HDKPDFJJ_03533 1e-173 ycbJ S Macrolide 2'-phosphotransferase
HDKPDFJJ_03534 4.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
HDKPDFJJ_03535 2.1e-123 ycbG K FCD
HDKPDFJJ_03536 6.5e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HDKPDFJJ_03537 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HDKPDFJJ_03538 3.4e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDKPDFJJ_03539 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HDKPDFJJ_03540 9e-170 glnL T Regulator
HDKPDFJJ_03541 9.4e-229 phoQ 2.7.13.3 T Histidine kinase
HDKPDFJJ_03542 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
HDKPDFJJ_03543 9.6e-256 agcS E Sodium alanine symporter
HDKPDFJJ_03544 1.5e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HDKPDFJJ_03545 8.2e-260 mmuP E amino acid
HDKPDFJJ_03546 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HDKPDFJJ_03548 4.9e-128 K UTRA
HDKPDFJJ_03549 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDKPDFJJ_03550 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDKPDFJJ_03551 1.1e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDKPDFJJ_03552 3.3e-191 yceA S Belongs to the UPF0176 family
HDKPDFJJ_03553 2.1e-252 S Erythromycin esterase
HDKPDFJJ_03554 4.6e-45 ybfN
HDKPDFJJ_03555 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HDKPDFJJ_03556 2.7e-85 ybfM S SNARE associated Golgi protein
HDKPDFJJ_03557 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDKPDFJJ_03558 1.4e-164 S Alpha/beta hydrolase family
HDKPDFJJ_03560 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HDKPDFJJ_03561 4.3e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HDKPDFJJ_03562 2.3e-145 msmR K AraC-like ligand binding domain
HDKPDFJJ_03563 4.5e-158 ybfH EG EamA-like transporter family
HDKPDFJJ_03564 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HDKPDFJJ_03566 6e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
HDKPDFJJ_03567 7.4e-169 ybfA 3.4.15.5 K FR47-like protein
HDKPDFJJ_03568 1.5e-34 S Protein of unknown function (DUF2651)
HDKPDFJJ_03569 7.3e-258 glpT G -transporter
HDKPDFJJ_03570 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HDKPDFJJ_03571 3e-290 ybeC E amino acid
HDKPDFJJ_03572 4.9e-41 ybyB
HDKPDFJJ_03573 5.1e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HDKPDFJJ_03574 1.2e-149 ybxI 3.5.2.6 V beta-lactamase
HDKPDFJJ_03575 4.9e-30 ybxH S Family of unknown function (DUF5370)
HDKPDFJJ_03576 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
HDKPDFJJ_03577 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HDKPDFJJ_03578 5.7e-214 ybdO S Domain of unknown function (DUF4885)
HDKPDFJJ_03579 7.7e-152 ybdN
HDKPDFJJ_03580 4.4e-138 KLT Protein tyrosine kinase
HDKPDFJJ_03582 1.1e-170 T His Kinase A (phospho-acceptor) domain
HDKPDFJJ_03583 8.5e-122 T Transcriptional regulatory protein, C terminal
HDKPDFJJ_03584 6.9e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HDKPDFJJ_03585 3.3e-56
HDKPDFJJ_03586 6.5e-202 ybcL EGP Major facilitator Superfamily
HDKPDFJJ_03587 5.1e-50 ybzH K Helix-turn-helix domain
HDKPDFJJ_03588 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HDKPDFJJ_03589 7.3e-46
HDKPDFJJ_03591 1.6e-91 can 4.2.1.1 P carbonic anhydrase
HDKPDFJJ_03592 0.0 ybcC S Belongs to the UPF0753 family
HDKPDFJJ_03593 2.2e-274 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HDKPDFJJ_03594 5.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDKPDFJJ_03595 2.2e-119 adaA 3.2.2.21 K Transcriptional regulator
HDKPDFJJ_03596 1.8e-175 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HDKPDFJJ_03597 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDKPDFJJ_03598 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDKPDFJJ_03599 5.7e-224 ybbR S protein conserved in bacteria
HDKPDFJJ_03600 4.6e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDKPDFJJ_03601 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HDKPDFJJ_03602 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HDKPDFJJ_03608 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HDKPDFJJ_03609 1.9e-86 ybbJ J acetyltransferase
HDKPDFJJ_03610 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HDKPDFJJ_03611 1.4e-150 ybbH K transcriptional
HDKPDFJJ_03612 4.9e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDKPDFJJ_03613 5.4e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HDKPDFJJ_03614 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HDKPDFJJ_03615 1.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
HDKPDFJJ_03616 9.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HDKPDFJJ_03617 1.3e-163 feuA P Iron-uptake system-binding protein
HDKPDFJJ_03618 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_03619 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_03620 4.1e-141 ybbA S Putative esterase
HDKPDFJJ_03621 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
HDKPDFJJ_03623 6.7e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HDKPDFJJ_03627 1.8e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HDKPDFJJ_03628 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HDKPDFJJ_03629 4.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HDKPDFJJ_03630 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HDKPDFJJ_03631 5.2e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDKPDFJJ_03632 0.0 ydiF S ABC transporter
HDKPDFJJ_03633 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HDKPDFJJ_03634 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDKPDFJJ_03635 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HDKPDFJJ_03636 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDKPDFJJ_03637 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HDKPDFJJ_03638 7.9e-129 ydiL S CAAX protease self-immunity
HDKPDFJJ_03639 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDKPDFJJ_03640 3.7e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDKPDFJJ_03642 4.1e-40
HDKPDFJJ_03643 5.4e-235 yobL S Bacterial EndoU nuclease
HDKPDFJJ_03646 4.6e-65 yozB S Membrane
HDKPDFJJ_03647 1.1e-80 3.1.21.3 V Type I restriction modification DNA specificity domain
HDKPDFJJ_03648 1.4e-287 hsdM 2.1.1.72 V Type I restriction-modification system
HDKPDFJJ_03649 5e-104 3.1.21.3 V Type I restriction modification DNA specificity domain
HDKPDFJJ_03650 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HDKPDFJJ_03651 0.0 K NB-ARC domain
HDKPDFJJ_03652 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
HDKPDFJJ_03653 1.9e-253 gutA G MFS/sugar transport protein
HDKPDFJJ_03654 1.2e-174 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HDKPDFJJ_03655 8.7e-114 pspA KT Phage shock protein A
HDKPDFJJ_03656 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDKPDFJJ_03657 6.5e-134 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HDKPDFJJ_03658 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
HDKPDFJJ_03659 2.2e-193 S Ion transport 2 domain protein
HDKPDFJJ_03660 1.7e-257 iolT EGP Major facilitator Superfamily
HDKPDFJJ_03661 1.5e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HDKPDFJJ_03662 4.5e-64 ydjM M Lytic transglycolase
HDKPDFJJ_03663 9.1e-155 ydjN U Involved in the tonB-independent uptake of proteins
HDKPDFJJ_03665 1.4e-34 ydjO S Cold-inducible protein YdjO
HDKPDFJJ_03666 2.1e-154 ydjP I Alpha/beta hydrolase family
HDKPDFJJ_03667 1.3e-174 yeaA S Protein of unknown function (DUF4003)
HDKPDFJJ_03668 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HDKPDFJJ_03669 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HDKPDFJJ_03670 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDKPDFJJ_03671 5e-176 yeaC S COG0714 MoxR-like ATPases
HDKPDFJJ_03672 6.8e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HDKPDFJJ_03673 0.0 yebA E COG1305 Transglutaminase-like enzymes
HDKPDFJJ_03674 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HDKPDFJJ_03675 1e-211 pbuG S permease
HDKPDFJJ_03676 2.3e-118 yebC M Membrane
HDKPDFJJ_03678 8.9e-93 yebE S UPF0316 protein
HDKPDFJJ_03679 8e-28 yebG S NETI protein
HDKPDFJJ_03680 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDKPDFJJ_03681 2.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDKPDFJJ_03682 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDKPDFJJ_03683 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HDKPDFJJ_03684 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDKPDFJJ_03685 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDKPDFJJ_03686 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDKPDFJJ_03687 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDKPDFJJ_03688 1.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HDKPDFJJ_03689 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDKPDFJJ_03690 2.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HDKPDFJJ_03691 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
HDKPDFJJ_03692 1e-72 K helix_turn_helix ASNC type
HDKPDFJJ_03693 3.7e-227 yjeH E Amino acid permease
HDKPDFJJ_03694 4.6e-27 S Protein of unknown function (DUF2892)
HDKPDFJJ_03695 0.0 yerA 3.5.4.2 F adenine deaminase
HDKPDFJJ_03696 4.9e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
HDKPDFJJ_03697 4.8e-51 yerC S protein conserved in bacteria
HDKPDFJJ_03698 2e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HDKPDFJJ_03699 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HDKPDFJJ_03700 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HDKPDFJJ_03701 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDKPDFJJ_03702 3e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
HDKPDFJJ_03703 6.6e-195 yerI S homoserine kinase type II (protein kinase fold)
HDKPDFJJ_03704 1.6e-123 sapB S MgtC SapB transporter
HDKPDFJJ_03705 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDKPDFJJ_03706 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDKPDFJJ_03707 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDKPDFJJ_03708 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDKPDFJJ_03709 1.6e-146 yerO K Transcriptional regulator
HDKPDFJJ_03710 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HDKPDFJJ_03711 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HDKPDFJJ_03712 6.4e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDKPDFJJ_03716 1.1e-100 S response regulator aspartate phosphatase
HDKPDFJJ_03718 5.1e-42 S Immunity protein 22
HDKPDFJJ_03719 4.3e-187 yobL S Bacterial EndoU nuclease
HDKPDFJJ_03721 1.7e-96 L endonuclease activity
HDKPDFJJ_03722 1.2e-167 3.4.24.40 CO amine dehydrogenase activity
HDKPDFJJ_03723 1.8e-39
HDKPDFJJ_03724 7.9e-213 S Tetratricopeptide repeat
HDKPDFJJ_03726 9.4e-127 yeeN K transcriptional regulatory protein
HDKPDFJJ_03728 8.8e-99 dhaR3 K Transcriptional regulator
HDKPDFJJ_03729 2.2e-81 yesE S SnoaL-like domain
HDKPDFJJ_03730 2e-144 yesF GM NAD(P)H-binding
HDKPDFJJ_03731 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HDKPDFJJ_03732 1.5e-45 cotJB S CotJB protein
HDKPDFJJ_03733 5.2e-104 cotJC P Spore Coat
HDKPDFJJ_03734 6e-102 yesJ K Acetyltransferase (GNAT) family
HDKPDFJJ_03735 1.8e-102 yesL S Protein of unknown function, DUF624
HDKPDFJJ_03736 0.0 yesM 2.7.13.3 T Histidine kinase
HDKPDFJJ_03737 1e-201 yesN K helix_turn_helix, arabinose operon control protein
HDKPDFJJ_03738 1.6e-246 yesO G Bacterial extracellular solute-binding protein
HDKPDFJJ_03739 3.1e-170 yesP G Binding-protein-dependent transport system inner membrane component
HDKPDFJJ_03740 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
HDKPDFJJ_03741 7.8e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HDKPDFJJ_03742 0.0 yesS K Transcriptional regulator
HDKPDFJJ_03743 2.7e-131 E GDSL-like Lipase/Acylhydrolase
HDKPDFJJ_03744 3.2e-129 yesU S Domain of unknown function (DUF1961)
HDKPDFJJ_03745 1e-113 yesV S Protein of unknown function, DUF624
HDKPDFJJ_03746 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HDKPDFJJ_03747 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HDKPDFJJ_03748 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
HDKPDFJJ_03749 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HDKPDFJJ_03750 0.0 yetA
HDKPDFJJ_03751 4.5e-79 yetA
HDKPDFJJ_03752 6.2e-290 lplA G Bacterial extracellular solute-binding protein
HDKPDFJJ_03753 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HDKPDFJJ_03754 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HDKPDFJJ_03755 2.1e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HDKPDFJJ_03756 6.1e-123 yetF S membrane
HDKPDFJJ_03757 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HDKPDFJJ_03758 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDKPDFJJ_03759 2.4e-34
HDKPDFJJ_03760 8.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HDKPDFJJ_03761 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HDKPDFJJ_03762 2.6e-104 yetJ S Belongs to the BI1 family
HDKPDFJJ_03763 2.4e-30 yetM CH FAD binding domain
HDKPDFJJ_03764 3.6e-199 yetN S Protein of unknown function (DUF3900)
HDKPDFJJ_03765 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HDKPDFJJ_03766 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HDKPDFJJ_03767 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
HDKPDFJJ_03768 1.9e-172 yfnG 4.2.1.45 M dehydratase
HDKPDFJJ_03769 5.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
HDKPDFJJ_03770 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HDKPDFJJ_03771 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
HDKPDFJJ_03772 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
HDKPDFJJ_03773 2.5e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HDKPDFJJ_03774 1.4e-240 yfnA E amino acid
HDKPDFJJ_03775 2.4e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HDKPDFJJ_03776 1.1e-113 yfmS NT chemotaxis protein
HDKPDFJJ_03777 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HDKPDFJJ_03778 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
HDKPDFJJ_03779 2.4e-69 yfmP K transcriptional
HDKPDFJJ_03780 9.5e-209 yfmO EGP Major facilitator Superfamily
HDKPDFJJ_03781 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HDKPDFJJ_03782 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HDKPDFJJ_03783 6.8e-75 yfmK 2.3.1.128 K acetyltransferase
HDKPDFJJ_03784 6.7e-187 yfmJ S N-terminal domain of oxidoreductase
HDKPDFJJ_03785 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HDKPDFJJ_03786 3.6e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_03787 6.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_03788 1.2e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HDKPDFJJ_03789 2.6e-24 S Protein of unknown function (DUF3212)
HDKPDFJJ_03790 7.6e-58 yflT S Heat induced stress protein YflT
HDKPDFJJ_03791 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HDKPDFJJ_03792 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
HDKPDFJJ_03793 4.1e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HDKPDFJJ_03794 2.4e-116 citT T response regulator
HDKPDFJJ_03795 1.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
HDKPDFJJ_03796 8.5e-227 citM C Citrate transporter
HDKPDFJJ_03797 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HDKPDFJJ_03798 7.4e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HDKPDFJJ_03799 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HDKPDFJJ_03800 1.9e-121 yflK S protein conserved in bacteria
HDKPDFJJ_03801 4e-18 yflJ S Protein of unknown function (DUF2639)
HDKPDFJJ_03802 4.1e-19 yflI
HDKPDFJJ_03803 1.5e-49 yflH S Protein of unknown function (DUF3243)
HDKPDFJJ_03804 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HDKPDFJJ_03805 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HDKPDFJJ_03806 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HDKPDFJJ_03807 6.6e-66 yhdN S Domain of unknown function (DUF1992)
HDKPDFJJ_03808 2.2e-252 agcS_1 E Sodium alanine symporter
HDKPDFJJ_03809 2.2e-25 yfkQ EG Spore germination protein
HDKPDFJJ_03810 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDKPDFJJ_03811 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HDKPDFJJ_03812 6.7e-133 treR K transcriptional
HDKPDFJJ_03813 1.1e-124 yfkO C nitroreductase
HDKPDFJJ_03814 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HDKPDFJJ_03815 4.3e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
HDKPDFJJ_03816 6.8e-207 ydiM EGP Major facilitator Superfamily
HDKPDFJJ_03817 1.3e-28 yfkK S Belongs to the UPF0435 family
HDKPDFJJ_03818 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDKPDFJJ_03819 8.4e-51 yfkI S gas vesicle protein
HDKPDFJJ_03820 9.7e-144 yihY S Belongs to the UPF0761 family
HDKPDFJJ_03822 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HDKPDFJJ_03823 6.1e-183 cax P COG0387 Ca2 H antiporter
HDKPDFJJ_03824 1.2e-146 yfkD S YfkD-like protein
HDKPDFJJ_03825 6e-149 yfkC M Mechanosensitive ion channel
HDKPDFJJ_03826 5.4e-222 yfkA S YfkB-like domain
HDKPDFJJ_03827 1.1e-26 yfjT
HDKPDFJJ_03828 1.7e-153 pdaA G deacetylase
HDKPDFJJ_03829 8e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HDKPDFJJ_03830 1.7e-184 corA P Mediates influx of magnesium ions
HDKPDFJJ_03831 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HDKPDFJJ_03832 5.3e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDKPDFJJ_03833 3.9e-44 S YfzA-like protein
HDKPDFJJ_03834 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDKPDFJJ_03835 9.6e-85 yfjM S Psort location Cytoplasmic, score
HDKPDFJJ_03836 4.3e-28 yfjL
HDKPDFJJ_03837 1.1e-189 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HDKPDFJJ_03838 5.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDKPDFJJ_03839 1.3e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDKPDFJJ_03840 2.8e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HDKPDFJJ_03841 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HDKPDFJJ_03842 1.3e-24 sspH S Belongs to the SspH family
HDKPDFJJ_03843 4e-56 yfjF S UPF0060 membrane protein
HDKPDFJJ_03844 6.5e-80 S Family of unknown function (DUF5381)
HDKPDFJJ_03845 1.8e-101 yfjD S Family of unknown function (DUF5381)
HDKPDFJJ_03846 1.5e-143 yfjC
HDKPDFJJ_03847 2e-190 yfjB
HDKPDFJJ_03848 2.6e-44 yfjA S Belongs to the WXG100 family
HDKPDFJJ_03849 8.4e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HDKPDFJJ_03850 2.7e-140 glvR K Helix-turn-helix domain, rpiR family
HDKPDFJJ_03851 2e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HDKPDFJJ_03852 0.0 yobO M COG5434 Endopolygalacturonase
HDKPDFJJ_03853 2.4e-306 yfiB3 V ABC transporter
HDKPDFJJ_03854 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HDKPDFJJ_03855 9.8e-65 mhqP S DoxX
HDKPDFJJ_03856 5.7e-163 yfiE 1.13.11.2 S glyoxalase
HDKPDFJJ_03858 2.6e-211 yxjM T Histidine kinase
HDKPDFJJ_03859 1e-111 KT LuxR family transcriptional regulator
HDKPDFJJ_03860 6.6e-165 V ABC transporter, ATP-binding protein
HDKPDFJJ_03861 8.9e-207 V ABC-2 family transporter protein
HDKPDFJJ_03862 7.6e-203 V COG0842 ABC-type multidrug transport system, permease component
HDKPDFJJ_03863 1.8e-93 padR K transcriptional
HDKPDFJJ_03864 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HDKPDFJJ_03865 2.9e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HDKPDFJJ_03866 1.8e-98 yfiT S Belongs to the metal hydrolase YfiT family
HDKPDFJJ_03867 1.4e-281 yfiU EGP Major facilitator Superfamily
HDKPDFJJ_03868 4.9e-79 yfiV K transcriptional
HDKPDFJJ_03869 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDKPDFJJ_03870 5.7e-175 yfiY P ABC transporter substrate-binding protein
HDKPDFJJ_03871 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_03872 1.3e-169 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HDKPDFJJ_03873 3.9e-167 yfhB 5.3.3.17 S PhzF family
HDKPDFJJ_03874 8.8e-107 yfhC C nitroreductase
HDKPDFJJ_03875 2.1e-25 yfhD S YfhD-like protein
HDKPDFJJ_03877 5.1e-170 yfhF S nucleoside-diphosphate sugar epimerase
HDKPDFJJ_03878 7.4e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HDKPDFJJ_03879 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HDKPDFJJ_03881 1.1e-209 yfhI EGP Major facilitator Superfamily
HDKPDFJJ_03882 6.2e-20 sspK S reproduction
HDKPDFJJ_03883 1.3e-44 yfhJ S WVELL protein
HDKPDFJJ_03884 5.1e-90 batE T Bacterial SH3 domain homologues
HDKPDFJJ_03885 3.5e-51 yfhL S SdpI/YhfL protein family
HDKPDFJJ_03886 2.2e-170 yfhM S Alpha beta hydrolase
HDKPDFJJ_03887 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDKPDFJJ_03888 0.0 yfhO S Bacterial membrane protein YfhO
HDKPDFJJ_03889 1.2e-185 yfhP S membrane-bound metal-dependent
HDKPDFJJ_03890 3.3e-210 mutY L A G-specific
HDKPDFJJ_03891 6.9e-36 yfhS
HDKPDFJJ_03892 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDKPDFJJ_03893 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HDKPDFJJ_03894 1.5e-37 ygaB S YgaB-like protein
HDKPDFJJ_03895 1.3e-104 ygaC J Belongs to the UPF0374 family
HDKPDFJJ_03896 1.8e-301 ygaD V ABC transporter
HDKPDFJJ_03897 3.3e-179 ygaE S Membrane
HDKPDFJJ_03898 1.7e-243 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HDKPDFJJ_03899 2.4e-86 bcp 1.11.1.15 O Peroxiredoxin
HDKPDFJJ_03900 4e-80 perR P Belongs to the Fur family
HDKPDFJJ_03901 9.5e-56 ygzB S UPF0295 protein
HDKPDFJJ_03902 2.5e-166 ygxA S Nucleotidyltransferase-like
HDKPDFJJ_03903 2.9e-76 ctsR K Belongs to the CtsR family
HDKPDFJJ_03904 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HDKPDFJJ_03905 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HDKPDFJJ_03906 0.0 clpC O Belongs to the ClpA ClpB family
HDKPDFJJ_03907 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDKPDFJJ_03908 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HDKPDFJJ_03909 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HDKPDFJJ_03910 4.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HDKPDFJJ_03911 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HDKPDFJJ_03912 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDKPDFJJ_03913 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HDKPDFJJ_03914 7.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDKPDFJJ_03915 4e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDKPDFJJ_03916 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDKPDFJJ_03917 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HDKPDFJJ_03918 4.4e-115 sigH K Belongs to the sigma-70 factor family
HDKPDFJJ_03919 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDKPDFJJ_03920 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HDKPDFJJ_03921 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDKPDFJJ_03922 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDKPDFJJ_03923 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDKPDFJJ_03924 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDKPDFJJ_03925 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HDKPDFJJ_03926 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDKPDFJJ_03927 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDKPDFJJ_03928 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HDKPDFJJ_03929 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDKPDFJJ_03930 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDKPDFJJ_03931 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDKPDFJJ_03932 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDKPDFJJ_03933 2.7e-182 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HDKPDFJJ_03934 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HDKPDFJJ_03935 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDKPDFJJ_03936 3e-105 rplD J Forms part of the polypeptide exit tunnel
HDKPDFJJ_03937 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDKPDFJJ_03938 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDKPDFJJ_03939 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDKPDFJJ_03940 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDKPDFJJ_03941 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDKPDFJJ_03942 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDKPDFJJ_03943 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HDKPDFJJ_03944 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDKPDFJJ_03945 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDKPDFJJ_03946 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDKPDFJJ_03947 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDKPDFJJ_03948 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDKPDFJJ_03949 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDKPDFJJ_03950 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDKPDFJJ_03951 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDKPDFJJ_03952 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDKPDFJJ_03953 1.9e-23 rpmD J Ribosomal protein L30
HDKPDFJJ_03954 1.8e-72 rplO J binds to the 23S rRNA
HDKPDFJJ_03955 2.1e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDKPDFJJ_03956 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDKPDFJJ_03957 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HDKPDFJJ_03958 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDKPDFJJ_03959 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HDKPDFJJ_03960 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDKPDFJJ_03961 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDKPDFJJ_03962 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDKPDFJJ_03963 3.6e-58 rplQ J Ribosomal protein L17
HDKPDFJJ_03964 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDKPDFJJ_03965 2.2e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDKPDFJJ_03966 3e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDKPDFJJ_03967 2.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDKPDFJJ_03968 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDKPDFJJ_03969 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HDKPDFJJ_03970 1.2e-143 ybaJ Q Methyltransferase domain
HDKPDFJJ_03971 9.7e-66 ybaK S Protein of unknown function (DUF2521)
HDKPDFJJ_03972 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HDKPDFJJ_03973 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HDKPDFJJ_03974 1.2e-84 gerD
HDKPDFJJ_03975 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HDKPDFJJ_03976 2.7e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HDKPDFJJ_03977 1.7e-30 csfB S Inhibitor of sigma-G Gin
HDKPDFJJ_03978 2.2e-100 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HDKPDFJJ_03979 9.9e-203 yaaN P Belongs to the TelA family
HDKPDFJJ_03980 2.5e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HDKPDFJJ_03981 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDKPDFJJ_03982 2.2e-54 yaaQ S protein conserved in bacteria
HDKPDFJJ_03983 1.5e-71 yaaR S protein conserved in bacteria
HDKPDFJJ_03984 1.1e-181 holB 2.7.7.7 L DNA polymerase III
HDKPDFJJ_03985 6.1e-146 yaaT S stage 0 sporulation protein
HDKPDFJJ_03986 4.8e-31 yabA L Involved in initiation control of chromosome replication
HDKPDFJJ_03987 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HDKPDFJJ_03988 1.5e-49 yazA L endonuclease containing a URI domain
HDKPDFJJ_03989 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDKPDFJJ_03990 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HDKPDFJJ_03991 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDKPDFJJ_03992 2.6e-143 tatD L hydrolase, TatD
HDKPDFJJ_03993 2e-167 rpfB GH23 T protein conserved in bacteria
HDKPDFJJ_03994 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDKPDFJJ_03995 4.5e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDKPDFJJ_03996 1.6e-136 yabG S peptidase
HDKPDFJJ_03997 7.8e-39 veg S protein conserved in bacteria
HDKPDFJJ_03998 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDKPDFJJ_03999 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HDKPDFJJ_04000 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HDKPDFJJ_04001 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HDKPDFJJ_04002 5.6e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDKPDFJJ_04003 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDKPDFJJ_04004 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HDKPDFJJ_04005 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDKPDFJJ_04006 2.4e-39 yabK S Peptide ABC transporter permease
HDKPDFJJ_04007 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDKPDFJJ_04008 1.5e-92 spoVT K stage V sporulation protein
HDKPDFJJ_04009 1.1e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HDKPDFJJ_04010 3.3e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HDKPDFJJ_04011 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HDKPDFJJ_04012 1.5e-49 yabP S Sporulation protein YabP
HDKPDFJJ_04013 9.5e-107 yabQ S spore cortex biosynthesis protein
HDKPDFJJ_04014 1.1e-44 divIC D Septum formation initiator
HDKPDFJJ_04015 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HDKPDFJJ_04018 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HDKPDFJJ_04019 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HDKPDFJJ_04020 6.3e-185 KLT serine threonine protein kinase
HDKPDFJJ_04021 1.9e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDKPDFJJ_04022 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDKPDFJJ_04023 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDKPDFJJ_04024 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HDKPDFJJ_04025 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDKPDFJJ_04026 7.7e-152 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HDKPDFJJ_04027 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDKPDFJJ_04028 1.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HDKPDFJJ_04029 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HDKPDFJJ_04030 6.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HDKPDFJJ_04031 5.9e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HDKPDFJJ_04032 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HDKPDFJJ_04033 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HDKPDFJJ_04034 4.1e-30 yazB K transcriptional
HDKPDFJJ_04035 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDKPDFJJ_04036 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HDKPDFJJ_04037 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HDKPDFJJ_04038 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HDKPDFJJ_04039 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDKPDFJJ_04040 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDKPDFJJ_04041 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDKPDFJJ_04042 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDKPDFJJ_04043 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
HDKPDFJJ_04044 2.6e-212 yaaH M Glycoside Hydrolase Family
HDKPDFJJ_04045 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HDKPDFJJ_04046 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HDKPDFJJ_04047 1.3e-09
HDKPDFJJ_04048 3.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDKPDFJJ_04049 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HDKPDFJJ_04050 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HDKPDFJJ_04051 1.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDKPDFJJ_04052 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HDKPDFJJ_04053 9.6e-180 yaaC S YaaC-like Protein
HDKPDFJJ_04054 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDKPDFJJ_04055 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)