ORF_ID e_value Gene_name EC_number CAZy COGs Description
IIPAIDOJ_00001 3.6e-196 L Replication protein
IIPAIDOJ_00003 1.1e-17
IIPAIDOJ_00004 5.2e-201 pre D plasmid recombination enzyme
IIPAIDOJ_00005 2.8e-66 K Transcriptional regulator
IIPAIDOJ_00008 5.4e-97 S Tetratricopeptide repeat
IIPAIDOJ_00009 3.4e-39 S COG NOG14552 non supervised orthologous group
IIPAIDOJ_00010 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
IIPAIDOJ_00011 2.4e-92 M1-753 M FR47-like protein
IIPAIDOJ_00012 3.5e-187 yuaG 3.4.21.72 S protein conserved in bacteria
IIPAIDOJ_00013 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
IIPAIDOJ_00014 3.9e-84 yuaE S DinB superfamily
IIPAIDOJ_00015 3.9e-107 yuaD
IIPAIDOJ_00016 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
IIPAIDOJ_00017 3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
IIPAIDOJ_00018 5.5e-95 yuaC K Belongs to the GbsR family
IIPAIDOJ_00019 2.2e-91 yuaB
IIPAIDOJ_00020 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
IIPAIDOJ_00021 4.6e-236 ktrB P Potassium
IIPAIDOJ_00022 1e-38 yiaA S yiaA/B two helix domain
IIPAIDOJ_00023 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IIPAIDOJ_00024 3.7e-274 yubD P Major Facilitator Superfamily
IIPAIDOJ_00025 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
IIPAIDOJ_00027 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IIPAIDOJ_00028 3.7e-189 yubA S transporter activity
IIPAIDOJ_00029 8.2e-182 ygjR S Oxidoreductase
IIPAIDOJ_00030 1.4e-250 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
IIPAIDOJ_00031 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
IIPAIDOJ_00032 6.7e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IIPAIDOJ_00033 3.8e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
IIPAIDOJ_00034 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
IIPAIDOJ_00035 7.3e-238 mcpA NT chemotaxis protein
IIPAIDOJ_00036 1.9e-294 mcpA NT chemotaxis protein
IIPAIDOJ_00037 2.6e-219 mcpA NT chemotaxis protein
IIPAIDOJ_00038 3.2e-225 mcpA NT chemotaxis protein
IIPAIDOJ_00039 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
IIPAIDOJ_00040 1e-35
IIPAIDOJ_00041 9e-71 yugU S Uncharacterised protein family UPF0047
IIPAIDOJ_00042 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
IIPAIDOJ_00043 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
IIPAIDOJ_00044 1.4e-116 yugP S Zn-dependent protease
IIPAIDOJ_00045 2.3e-38
IIPAIDOJ_00046 3.2e-53 mstX S Membrane-integrating protein Mistic
IIPAIDOJ_00047 2.2e-182 yugO P COG1226 Kef-type K transport systems
IIPAIDOJ_00048 1.7e-72 yugN S YugN-like family
IIPAIDOJ_00050 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
IIPAIDOJ_00051 1.2e-227 yugK C Dehydrogenase
IIPAIDOJ_00052 6.4e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
IIPAIDOJ_00053 4e-34 yuzA S Domain of unknown function (DUF378)
IIPAIDOJ_00054 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
IIPAIDOJ_00055 2.1e-199 yugH 2.6.1.1 E Aminotransferase
IIPAIDOJ_00056 1.6e-85 alaR K Transcriptional regulator
IIPAIDOJ_00057 3.2e-155 yugF I Hydrolase
IIPAIDOJ_00058 4.6e-39 yugE S Domain of unknown function (DUF1871)
IIPAIDOJ_00059 5.8e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IIPAIDOJ_00060 4.6e-233 T PhoQ Sensor
IIPAIDOJ_00061 7.4e-70 kapB G Kinase associated protein B
IIPAIDOJ_00062 1.9e-115 kapD L the KinA pathway to sporulation
IIPAIDOJ_00064 2.1e-183 yuxJ EGP Major facilitator Superfamily
IIPAIDOJ_00065 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
IIPAIDOJ_00066 6.3e-75 yuxK S protein conserved in bacteria
IIPAIDOJ_00067 6.3e-78 yufK S Family of unknown function (DUF5366)
IIPAIDOJ_00068 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IIPAIDOJ_00069 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
IIPAIDOJ_00070 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IIPAIDOJ_00071 1e-271 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IIPAIDOJ_00072 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
IIPAIDOJ_00073 7.8e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
IIPAIDOJ_00074 8.2e-233 maeN C COG3493 Na citrate symporter
IIPAIDOJ_00075 5e-15
IIPAIDOJ_00076 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IIPAIDOJ_00077 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IIPAIDOJ_00078 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IIPAIDOJ_00079 9.3e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IIPAIDOJ_00080 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IIPAIDOJ_00081 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IIPAIDOJ_00082 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
IIPAIDOJ_00083 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
IIPAIDOJ_00084 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIPAIDOJ_00085 0.0 comP 2.7.13.3 T Histidine kinase
IIPAIDOJ_00087 3e-147 comQ H Polyprenyl synthetase
IIPAIDOJ_00089 8.5e-23 yuzC
IIPAIDOJ_00090 1.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
IIPAIDOJ_00091 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIPAIDOJ_00092 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
IIPAIDOJ_00093 1e-66 yueI S Protein of unknown function (DUF1694)
IIPAIDOJ_00094 7.4e-39 yueH S YueH-like protein
IIPAIDOJ_00095 6.6e-31 yueG S Spore germination protein gerPA/gerPF
IIPAIDOJ_00096 3.2e-190 yueF S transporter activity
IIPAIDOJ_00097 2e-70 S Protein of unknown function (DUF2283)
IIPAIDOJ_00098 2.9e-24 S Protein of unknown function (DUF2642)
IIPAIDOJ_00099 4.8e-96 yueE S phosphohydrolase
IIPAIDOJ_00100 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIPAIDOJ_00101 3.3e-64 yueC S Family of unknown function (DUF5383)
IIPAIDOJ_00102 0.0 esaA S type VII secretion protein EsaA
IIPAIDOJ_00103 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IIPAIDOJ_00104 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
IIPAIDOJ_00105 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
IIPAIDOJ_00106 2.8e-45 esxA S Belongs to the WXG100 family
IIPAIDOJ_00107 1.9e-228 yukF QT Transcriptional regulator
IIPAIDOJ_00108 3e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
IIPAIDOJ_00109 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
IIPAIDOJ_00110 3.2e-35 mbtH S MbtH-like protein
IIPAIDOJ_00111 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPAIDOJ_00112 2.7e-174 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
IIPAIDOJ_00113 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
IIPAIDOJ_00114 1.2e-224 entC 5.4.4.2 HQ Isochorismate synthase
IIPAIDOJ_00115 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPAIDOJ_00116 5.6e-166 besA S Putative esterase
IIPAIDOJ_00117 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
IIPAIDOJ_00118 6.3e-92 bioY S Biotin biosynthesis protein
IIPAIDOJ_00119 3.9e-211 yuiF S antiporter
IIPAIDOJ_00120 2.9e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IIPAIDOJ_00121 2e-77 yuiD S protein conserved in bacteria
IIPAIDOJ_00122 2.1e-117 yuiC S protein conserved in bacteria
IIPAIDOJ_00123 8.4e-27 yuiB S Putative membrane protein
IIPAIDOJ_00124 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
IIPAIDOJ_00125 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
IIPAIDOJ_00127 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IIPAIDOJ_00128 8.5e-116 paiB K Putative FMN-binding domain
IIPAIDOJ_00129 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIPAIDOJ_00130 3.7e-63 erpA S Belongs to the HesB IscA family
IIPAIDOJ_00131 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IIPAIDOJ_00132 7e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IIPAIDOJ_00133 3.2e-39 yuzB S Belongs to the UPF0349 family
IIPAIDOJ_00134 7.7e-199 yutJ 1.6.99.3 C NADH dehydrogenase
IIPAIDOJ_00135 1.3e-54 yuzD S protein conserved in bacteria
IIPAIDOJ_00136 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
IIPAIDOJ_00137 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
IIPAIDOJ_00138 2.5e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IIPAIDOJ_00139 3.4e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IIPAIDOJ_00140 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
IIPAIDOJ_00141 1e-198 yutH S Spore coat protein
IIPAIDOJ_00142 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
IIPAIDOJ_00143 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IIPAIDOJ_00144 1e-75 yutE S Protein of unknown function DUF86
IIPAIDOJ_00145 9.7e-48 yutD S protein conserved in bacteria
IIPAIDOJ_00146 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IIPAIDOJ_00147 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IIPAIDOJ_00148 8.4e-195 lytH M Peptidase, M23
IIPAIDOJ_00149 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
IIPAIDOJ_00150 5.3e-47 yunC S Domain of unknown function (DUF1805)
IIPAIDOJ_00151 3.2e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IIPAIDOJ_00152 1e-140 yunE S membrane transporter protein
IIPAIDOJ_00153 4.3e-171 yunF S Protein of unknown function DUF72
IIPAIDOJ_00154 1.4e-59 yunG
IIPAIDOJ_00155 5.1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IIPAIDOJ_00156 7e-300 pucR QT COG2508 Regulator of polyketide synthase expression
IIPAIDOJ_00157 3.8e-230 pbuX F Permease family
IIPAIDOJ_00158 1.9e-223 pbuX F xanthine
IIPAIDOJ_00159 3.5e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IIPAIDOJ_00160 3.2e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IIPAIDOJ_00163 2.8e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IIPAIDOJ_00164 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IIPAIDOJ_00165 1.2e-144 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IIPAIDOJ_00166 9.9e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
IIPAIDOJ_00167 2.1e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IIPAIDOJ_00168 3.3e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IIPAIDOJ_00169 1.7e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IIPAIDOJ_00170 1.2e-168 bsn L Ribonuclease
IIPAIDOJ_00171 1.1e-203 msmX P Belongs to the ABC transporter superfamily
IIPAIDOJ_00172 3.3e-135 yurK K UTRA
IIPAIDOJ_00173 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
IIPAIDOJ_00174 2.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
IIPAIDOJ_00175 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
IIPAIDOJ_00176 2.7e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
IIPAIDOJ_00177 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IIPAIDOJ_00178 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
IIPAIDOJ_00179 2.1e-205 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
IIPAIDOJ_00181 1e-41
IIPAIDOJ_00182 6.8e-288 L Uncharacterized conserved protein (DUF2075)
IIPAIDOJ_00183 5.5e-53 S MazG-like family
IIPAIDOJ_00184 3.5e-271 sufB O FeS cluster assembly
IIPAIDOJ_00185 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
IIPAIDOJ_00186 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IIPAIDOJ_00187 1.4e-245 sufD O assembly protein SufD
IIPAIDOJ_00188 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IIPAIDOJ_00189 9.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IIPAIDOJ_00190 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
IIPAIDOJ_00191 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
IIPAIDOJ_00192 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IIPAIDOJ_00193 9.3e-56 yusD S SCP-2 sterol transfer family
IIPAIDOJ_00194 5.6e-55 traF CO Thioredoxin
IIPAIDOJ_00195 8.2e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
IIPAIDOJ_00196 1.1e-39 yusG S Protein of unknown function (DUF2553)
IIPAIDOJ_00197 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IIPAIDOJ_00198 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
IIPAIDOJ_00199 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
IIPAIDOJ_00200 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
IIPAIDOJ_00201 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
IIPAIDOJ_00202 8.1e-09 S YuzL-like protein
IIPAIDOJ_00203 4.2e-164 fadM E Proline dehydrogenase
IIPAIDOJ_00204 5.1e-40
IIPAIDOJ_00205 5.4e-53 yusN M Coat F domain
IIPAIDOJ_00206 2.6e-66 yusO K Iron dependent repressor, N-terminal DNA binding domain
IIPAIDOJ_00207 8.5e-293 yusP P Major facilitator superfamily
IIPAIDOJ_00208 7.1e-65 yusQ S Tautomerase enzyme
IIPAIDOJ_00209 5e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPAIDOJ_00210 5.7e-158 yusT K LysR substrate binding domain
IIPAIDOJ_00211 5.6e-39 yusU S Protein of unknown function (DUF2573)
IIPAIDOJ_00212 1e-153 yusV 3.6.3.34 HP ABC transporter
IIPAIDOJ_00213 1.1e-66 S YusW-like protein
IIPAIDOJ_00214 9.4e-301 pepF2 E COG1164 Oligoendopeptidase F
IIPAIDOJ_00215 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPAIDOJ_00216 2.7e-79 dps P Ferritin-like domain
IIPAIDOJ_00217 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IIPAIDOJ_00218 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_00219 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
IIPAIDOJ_00220 1.3e-157 yuxN K Transcriptional regulator
IIPAIDOJ_00221 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IIPAIDOJ_00222 2.3e-24 S Protein of unknown function (DUF3970)
IIPAIDOJ_00223 1.2e-245 gerAA EG Spore germination protein
IIPAIDOJ_00224 4.2e-195 gerAB E Spore germination protein
IIPAIDOJ_00225 4.1e-185 gerAC S Spore germination B3/ GerAC like, C-terminal
IIPAIDOJ_00226 6.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIPAIDOJ_00227 7.9e-186 vraS 2.7.13.3 T Histidine kinase
IIPAIDOJ_00228 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
IIPAIDOJ_00229 1.8e-119 liaG S Putative adhesin
IIPAIDOJ_00230 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IIPAIDOJ_00231 6.2e-61 liaI S membrane
IIPAIDOJ_00232 4.8e-227 yvqJ EGP Major facilitator Superfamily
IIPAIDOJ_00233 6.1e-100 yvqK 2.5.1.17 S Adenosyltransferase
IIPAIDOJ_00234 4e-240 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IIPAIDOJ_00235 1.7e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_00236 5.8e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IIPAIDOJ_00237 1.2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPAIDOJ_00238 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
IIPAIDOJ_00239 0.0 T PhoQ Sensor
IIPAIDOJ_00240 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_00241 3.6e-22
IIPAIDOJ_00242 9.5e-98 yvrI K RNA polymerase
IIPAIDOJ_00243 2.4e-19 S YvrJ protein family
IIPAIDOJ_00244 1.5e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
IIPAIDOJ_00245 1.3e-64 yvrL S Regulatory protein YrvL
IIPAIDOJ_00246 4.9e-208 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
IIPAIDOJ_00247 1.6e-123 macB V ABC transporter, ATP-binding protein
IIPAIDOJ_00248 2e-174 M Efflux transporter rnd family, mfp subunit
IIPAIDOJ_00249 9.8e-149 fhuC 3.6.3.34 HP ABC transporter
IIPAIDOJ_00250 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_00251 9.6e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_00252 2.2e-176 fhuD P ABC transporter
IIPAIDOJ_00253 4.9e-236 yvsH E Arginine ornithine antiporter
IIPAIDOJ_00254 6.5e-16 S Small spore protein J (Spore_SspJ)
IIPAIDOJ_00255 3.9e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
IIPAIDOJ_00256 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IIPAIDOJ_00257 2.2e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
IIPAIDOJ_00258 7.8e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
IIPAIDOJ_00259 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
IIPAIDOJ_00260 1.1e-155 yvgN S reductase
IIPAIDOJ_00261 2.1e-85 yvgO
IIPAIDOJ_00262 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
IIPAIDOJ_00263 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IIPAIDOJ_00264 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IIPAIDOJ_00265 0.0 helD 3.6.4.12 L DNA helicase
IIPAIDOJ_00267 1.6e-106 yvgT S membrane
IIPAIDOJ_00268 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
IIPAIDOJ_00269 2.7e-104 bdbD O Thioredoxin
IIPAIDOJ_00270 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IIPAIDOJ_00271 0.0 copA 3.6.3.54 P P-type ATPase
IIPAIDOJ_00272 1.5e-29 copZ P Copper resistance protein CopZ
IIPAIDOJ_00273 2.2e-48 csoR S transcriptional
IIPAIDOJ_00274 4.5e-194 yvaA 1.1.1.371 S Oxidoreductase
IIPAIDOJ_00275 5.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IIPAIDOJ_00276 0.0 yvaC S Fusaric acid resistance protein-like
IIPAIDOJ_00277 4.8e-72 yvaD S Family of unknown function (DUF5360)
IIPAIDOJ_00278 1.8e-54 yvaE P Small Multidrug Resistance protein
IIPAIDOJ_00279 1e-96 K Bacterial regulatory proteins, tetR family
IIPAIDOJ_00280 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPAIDOJ_00282 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IIPAIDOJ_00283 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IIPAIDOJ_00284 1.6e-142 est 3.1.1.1 S Carboxylesterase
IIPAIDOJ_00285 2.4e-23 secG U Preprotein translocase subunit SecG
IIPAIDOJ_00286 3.7e-153 yvaM S Serine aminopeptidase, S33
IIPAIDOJ_00287 7.5e-36 yvzC K Transcriptional
IIPAIDOJ_00288 4e-69 K transcriptional
IIPAIDOJ_00289 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
IIPAIDOJ_00290 1.4e-53 yodB K transcriptional
IIPAIDOJ_00291 3.8e-219 NT chemotaxis protein
IIPAIDOJ_00292 5.8e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IIPAIDOJ_00293 2.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IIPAIDOJ_00294 1.8e-108 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IIPAIDOJ_00295 1.2e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IIPAIDOJ_00296 2.1e-62 yvbF K Belongs to the GbsR family
IIPAIDOJ_00297 7.3e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IIPAIDOJ_00298 1.8e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IIPAIDOJ_00299 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IIPAIDOJ_00300 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IIPAIDOJ_00301 3.5e-97 yvbF K Belongs to the GbsR family
IIPAIDOJ_00302 3.5e-101 yvbG U UPF0056 membrane protein
IIPAIDOJ_00303 1.2e-111 yvbH S YvbH-like oligomerisation region
IIPAIDOJ_00304 9.8e-121 exoY M Membrane
IIPAIDOJ_00305 0.0 tcaA S response to antibiotic
IIPAIDOJ_00306 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
IIPAIDOJ_00307 1.9e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IIPAIDOJ_00308 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
IIPAIDOJ_00309 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIPAIDOJ_00310 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IIPAIDOJ_00311 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIPAIDOJ_00312 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IIPAIDOJ_00313 1.6e-252 araE EGP Major facilitator Superfamily
IIPAIDOJ_00314 5.5e-203 araR K transcriptional
IIPAIDOJ_00315 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIPAIDOJ_00316 3.9e-159 yvbU K Transcriptional regulator
IIPAIDOJ_00317 9.4e-156 yvbV EG EamA-like transporter family
IIPAIDOJ_00318 4.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
IIPAIDOJ_00319 3.2e-192 yvbX S Glycosyl hydrolase
IIPAIDOJ_00320 6.7e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IIPAIDOJ_00321 7.8e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IIPAIDOJ_00322 4.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IIPAIDOJ_00323 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIPAIDOJ_00324 2.7e-197 desK 2.7.13.3 T Histidine kinase
IIPAIDOJ_00325 5.3e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
IIPAIDOJ_00326 6.4e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
IIPAIDOJ_00327 2.6e-157 rsbQ S Alpha/beta hydrolase family
IIPAIDOJ_00328 7.2e-196 rsbU 3.1.3.3 T response regulator
IIPAIDOJ_00329 1.4e-250 galA 3.2.1.89 G arabinogalactan
IIPAIDOJ_00330 0.0 lacA 3.2.1.23 G beta-galactosidase
IIPAIDOJ_00331 7.2e-150 ganQ P transport
IIPAIDOJ_00332 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
IIPAIDOJ_00333 2.3e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
IIPAIDOJ_00334 1.8e-184 lacR K Transcriptional regulator
IIPAIDOJ_00335 1e-112 yvfI K COG2186 Transcriptional regulators
IIPAIDOJ_00336 5.7e-308 yvfH C L-lactate permease
IIPAIDOJ_00337 1.4e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IIPAIDOJ_00338 1e-31 yvfG S YvfG protein
IIPAIDOJ_00339 2.2e-187 yvfF GM Exopolysaccharide biosynthesis protein
IIPAIDOJ_00340 1.8e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IIPAIDOJ_00341 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
IIPAIDOJ_00342 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IIPAIDOJ_00343 3.7e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIPAIDOJ_00344 3.5e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
IIPAIDOJ_00345 4.4e-205 epsI GM pyruvyl transferase
IIPAIDOJ_00346 4.4e-194 epsH GT2 S Glycosyltransferase like family 2
IIPAIDOJ_00347 1.1e-206 epsG S EpsG family
IIPAIDOJ_00348 1.9e-217 epsF GT4 M Glycosyl transferases group 1
IIPAIDOJ_00349 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IIPAIDOJ_00350 9.8e-219 epsD GT4 M Glycosyl transferase 4-like
IIPAIDOJ_00351 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
IIPAIDOJ_00352 3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
IIPAIDOJ_00353 2e-118 ywqC M biosynthesis protein
IIPAIDOJ_00354 6.3e-76 slr K transcriptional
IIPAIDOJ_00355 5.9e-277 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
IIPAIDOJ_00356 4.6e-93 padC Q Phenolic acid decarboxylase
IIPAIDOJ_00357 1.6e-38 MA20_18690 S Protein of unknown function (DUF3237)
IIPAIDOJ_00358 1.6e-26 MA20_18690 S Protein of unknown function (DUF3237)
IIPAIDOJ_00359 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IIPAIDOJ_00360 4.3e-258 pbpE V Beta-lactamase
IIPAIDOJ_00361 9.3e-66
IIPAIDOJ_00362 1.7e-273 sacB 2.4.1.10 GH68 M levansucrase activity
IIPAIDOJ_00363 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
IIPAIDOJ_00364 1.8e-295 yveA E amino acid
IIPAIDOJ_00365 7.4e-106 yvdT K Transcriptional regulator
IIPAIDOJ_00366 6.7e-51 ykkC P Small Multidrug Resistance protein
IIPAIDOJ_00367 7.1e-50 sugE P Small Multidrug Resistance protein
IIPAIDOJ_00368 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
IIPAIDOJ_00369 2.3e-173 S Patatin-like phospholipase
IIPAIDOJ_00371 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IIPAIDOJ_00372 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
IIPAIDOJ_00373 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
IIPAIDOJ_00374 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
IIPAIDOJ_00375 2.3e-151 malA S Protein of unknown function (DUF1189)
IIPAIDOJ_00376 3.9e-148 malD P transport
IIPAIDOJ_00377 2.9e-243 malC P COG1175 ABC-type sugar transport systems, permease components
IIPAIDOJ_00378 4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
IIPAIDOJ_00379 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
IIPAIDOJ_00380 1.8e-173 yvdE K Transcriptional regulator
IIPAIDOJ_00381 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
IIPAIDOJ_00382 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
IIPAIDOJ_00383 1.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
IIPAIDOJ_00384 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IIPAIDOJ_00385 2.5e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIPAIDOJ_00386 0.0 yxdM V ABC transporter (permease)
IIPAIDOJ_00387 5.6e-141 yvcR V ABC transporter, ATP-binding protein
IIPAIDOJ_00388 5.8e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
IIPAIDOJ_00389 9.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_00390 1.8e-33
IIPAIDOJ_00391 1e-144 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
IIPAIDOJ_00392 1.6e-36 crh G Phosphocarrier protein Chr
IIPAIDOJ_00393 4.1e-170 whiA K May be required for sporulation
IIPAIDOJ_00394 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IIPAIDOJ_00395 5.7e-166 rapZ S Displays ATPase and GTPase activities
IIPAIDOJ_00396 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IIPAIDOJ_00397 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IIPAIDOJ_00398 7.3e-99 usp CBM50 M protein conserved in bacteria
IIPAIDOJ_00399 6.5e-276 S COG0457 FOG TPR repeat
IIPAIDOJ_00400 0.0 msbA2 3.6.3.44 V ABC transporter
IIPAIDOJ_00402 0.0
IIPAIDOJ_00403 1.3e-120
IIPAIDOJ_00404 4.8e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
IIPAIDOJ_00405 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IIPAIDOJ_00406 1.9e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IIPAIDOJ_00407 6.9e-113 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IIPAIDOJ_00408 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IIPAIDOJ_00409 1.7e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IIPAIDOJ_00410 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IIPAIDOJ_00411 6.9e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IIPAIDOJ_00412 4.5e-140 yvpB NU protein conserved in bacteria
IIPAIDOJ_00413 1.2e-120 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
IIPAIDOJ_00414 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
IIPAIDOJ_00415 1.9e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IIPAIDOJ_00416 1.1e-159 yvoD P COG0370 Fe2 transport system protein B
IIPAIDOJ_00417 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IIPAIDOJ_00418 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IIPAIDOJ_00419 9.2e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IIPAIDOJ_00420 9.8e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IIPAIDOJ_00421 8.9e-133 yvoA K transcriptional
IIPAIDOJ_00422 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
IIPAIDOJ_00423 1.2e-50 yvlD S Membrane
IIPAIDOJ_00424 2.6e-26 pspB KT PspC domain
IIPAIDOJ_00425 5.4e-166 yvlB S Putative adhesin
IIPAIDOJ_00426 1.8e-48 yvlA
IIPAIDOJ_00427 5.7e-33 yvkN
IIPAIDOJ_00428 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IIPAIDOJ_00429 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IIPAIDOJ_00430 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IIPAIDOJ_00431 1.2e-30 csbA S protein conserved in bacteria
IIPAIDOJ_00432 0.0 yvkC 2.7.9.2 GT Phosphotransferase
IIPAIDOJ_00433 1.6e-100 yvkB K Transcriptional regulator
IIPAIDOJ_00434 2.8e-225 yvkA EGP Major facilitator Superfamily
IIPAIDOJ_00435 5.4e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IIPAIDOJ_00436 5.3e-56 swrA S Swarming motility protein
IIPAIDOJ_00437 2.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
IIPAIDOJ_00438 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IIPAIDOJ_00439 1.6e-123 ftsE D cell division ATP-binding protein FtsE
IIPAIDOJ_00440 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
IIPAIDOJ_00441 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
IIPAIDOJ_00442 3.9e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IIPAIDOJ_00443 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IIPAIDOJ_00444 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IIPAIDOJ_00445 1.1e-49
IIPAIDOJ_00446 1.9e-08 fliT S bacterial-type flagellum organization
IIPAIDOJ_00447 2.9e-69 fliS N flagellar protein FliS
IIPAIDOJ_00448 2.6e-248 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IIPAIDOJ_00449 1.2e-52 flaG N flagellar protein FlaG
IIPAIDOJ_00450 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IIPAIDOJ_00451 1.3e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IIPAIDOJ_00452 1.2e-71 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IIPAIDOJ_00453 4.8e-49 yviE
IIPAIDOJ_00454 7.8e-155 flgL N Belongs to the bacterial flagellin family
IIPAIDOJ_00455 1.2e-264 flgK N flagellar hook-associated protein
IIPAIDOJ_00456 2.4e-78 flgN NOU FlgN protein
IIPAIDOJ_00457 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
IIPAIDOJ_00458 4.6e-73 yvyF S flagellar protein
IIPAIDOJ_00459 6.8e-125 comFC S Phosphoribosyl transferase domain
IIPAIDOJ_00460 3.7e-45 comFB S Late competence development protein ComFB
IIPAIDOJ_00461 4.4e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IIPAIDOJ_00462 2.1e-154 degV S protein conserved in bacteria
IIPAIDOJ_00463 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIPAIDOJ_00464 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IIPAIDOJ_00465 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
IIPAIDOJ_00466 5.9e-163 yvhJ K Transcriptional regulator
IIPAIDOJ_00467 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IIPAIDOJ_00468 6.2e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
IIPAIDOJ_00469 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
IIPAIDOJ_00470 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
IIPAIDOJ_00471 5.4e-262 tuaE M Teichuronic acid biosynthesis protein
IIPAIDOJ_00472 9.9e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IIPAIDOJ_00473 1.4e-217 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
IIPAIDOJ_00474 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIPAIDOJ_00475 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IIPAIDOJ_00476 1.5e-94 M Glycosyltransferase like family 2
IIPAIDOJ_00477 1.2e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IIPAIDOJ_00478 0.0 lytB 3.5.1.28 D Stage II sporulation protein
IIPAIDOJ_00479 1e-11
IIPAIDOJ_00480 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IIPAIDOJ_00481 6.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IIPAIDOJ_00482 2.7e-88 M Glycosyltransferase like family 2
IIPAIDOJ_00483 5.4e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IIPAIDOJ_00484 3.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IIPAIDOJ_00485 4.5e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IIPAIDOJ_00486 1.7e-274 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IIPAIDOJ_00487 1e-132 tagG GM Transport permease protein
IIPAIDOJ_00488 5.2e-90
IIPAIDOJ_00489 2.7e-55
IIPAIDOJ_00490 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IIPAIDOJ_00491 2.9e-89 ggaA M Glycosyltransferase like family 2
IIPAIDOJ_00492 2.5e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IIPAIDOJ_00493 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
IIPAIDOJ_00494 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IIPAIDOJ_00495 1.5e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IIPAIDOJ_00496 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
IIPAIDOJ_00497 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
IIPAIDOJ_00498 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IIPAIDOJ_00499 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IIPAIDOJ_00500 2.3e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IIPAIDOJ_00501 2.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
IIPAIDOJ_00502 5.1e-265 gerBA EG Spore germination protein
IIPAIDOJ_00503 8.1e-194 gerBB E Spore germination protein
IIPAIDOJ_00504 2.2e-207 gerAC S Spore germination protein
IIPAIDOJ_00505 7.8e-247 ywtG EGP Major facilitator Superfamily
IIPAIDOJ_00506 2.4e-170 ywtF K Transcriptional regulator
IIPAIDOJ_00507 9.1e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
IIPAIDOJ_00508 2.7e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IIPAIDOJ_00509 3.6e-21 ywtC
IIPAIDOJ_00510 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IIPAIDOJ_00511 8.6e-70 pgsC S biosynthesis protein
IIPAIDOJ_00512 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
IIPAIDOJ_00513 5.5e-178 rbsR K transcriptional
IIPAIDOJ_00514 8.4e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IIPAIDOJ_00515 5.8e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IIPAIDOJ_00516 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IIPAIDOJ_00517 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
IIPAIDOJ_00518 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
IIPAIDOJ_00519 9.6e-92 batE T Sh3 type 3 domain protein
IIPAIDOJ_00520 8e-48 ywsA S Protein of unknown function (DUF3892)
IIPAIDOJ_00521 1.3e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
IIPAIDOJ_00522 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
IIPAIDOJ_00523 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IIPAIDOJ_00524 1.1e-169 alsR K LysR substrate binding domain
IIPAIDOJ_00525 1.4e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IIPAIDOJ_00526 5.4e-124 ywrJ
IIPAIDOJ_00527 1.7e-122 cotB
IIPAIDOJ_00528 6.9e-206 cotH M Spore Coat
IIPAIDOJ_00529 1.3e-12
IIPAIDOJ_00530 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IIPAIDOJ_00531 5e-54 S Domain of unknown function (DUF4181)
IIPAIDOJ_00532 8.2e-309 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IIPAIDOJ_00533 8e-82 ywrC K Transcriptional regulator
IIPAIDOJ_00534 1.2e-103 ywrB P Chromate transporter
IIPAIDOJ_00535 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
IIPAIDOJ_00537 3.5e-97 ywqN S NAD(P)H-dependent
IIPAIDOJ_00538 5.5e-161 K Transcriptional regulator
IIPAIDOJ_00539 2.8e-115 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IIPAIDOJ_00540 3.9e-25
IIPAIDOJ_00541 2.7e-242 ywqJ S Pre-toxin TG
IIPAIDOJ_00542 3.9e-38 ywqI S Family of unknown function (DUF5344)
IIPAIDOJ_00543 3.1e-21 S Domain of unknown function (DUF5082)
IIPAIDOJ_00544 1.3e-153 ywqG S Domain of unknown function (DUF1963)
IIPAIDOJ_00545 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IIPAIDOJ_00546 2.1e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
IIPAIDOJ_00547 8.4e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
IIPAIDOJ_00548 2e-116 ywqC M biosynthesis protein
IIPAIDOJ_00549 1.2e-17
IIPAIDOJ_00550 2.7e-307 ywqB S SWIM zinc finger
IIPAIDOJ_00551 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IIPAIDOJ_00552 1.5e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
IIPAIDOJ_00553 5.7e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
IIPAIDOJ_00554 3.7e-57 ssbB L Single-stranded DNA-binding protein
IIPAIDOJ_00555 3.8e-66 ywpG
IIPAIDOJ_00556 1.1e-66 ywpF S YwpF-like protein
IIPAIDOJ_00557 3e-84 srtA 3.4.22.70 M Sortase family
IIPAIDOJ_00558 0.0 M1-568 M cell wall anchor domain
IIPAIDOJ_00559 5.8e-173 M1-574 T Transcriptional regulatory protein, C terminal
IIPAIDOJ_00560 0.0 ywpD T PhoQ Sensor
IIPAIDOJ_00561 1.9e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IIPAIDOJ_00562 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIPAIDOJ_00563 7.5e-197 S aspartate phosphatase
IIPAIDOJ_00564 8.3e-140 flhP N flagellar basal body
IIPAIDOJ_00565 1.7e-124 flhO N flagellar basal body
IIPAIDOJ_00566 3.5e-180 mbl D Rod shape-determining protein
IIPAIDOJ_00567 3e-44 spoIIID K Stage III sporulation protein D
IIPAIDOJ_00568 2.1e-70 ywoH K COG1846 Transcriptional regulators
IIPAIDOJ_00569 7.8e-211 ywoG EGP Major facilitator Superfamily
IIPAIDOJ_00571 3e-230 ywoF P Right handed beta helix region
IIPAIDOJ_00572 3.1e-278 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
IIPAIDOJ_00573 2.4e-240 ywoD EGP Major facilitator superfamily
IIPAIDOJ_00574 6.8e-104 phzA Q Isochorismatase family
IIPAIDOJ_00575 1.5e-77
IIPAIDOJ_00576 4.3e-225 amt P Ammonium transporter
IIPAIDOJ_00577 1.6e-58 nrgB K Belongs to the P(II) protein family
IIPAIDOJ_00578 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
IIPAIDOJ_00579 7.8e-73 ywnJ S VanZ like family
IIPAIDOJ_00580 2e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
IIPAIDOJ_00581 2.7e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
IIPAIDOJ_00582 8.9e-10 ywnC S Family of unknown function (DUF5362)
IIPAIDOJ_00583 2.2e-70 ywnF S Family of unknown function (DUF5392)
IIPAIDOJ_00584 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIPAIDOJ_00585 5.3e-144 mta K transcriptional
IIPAIDOJ_00586 1.7e-58 ywnC S Family of unknown function (DUF5362)
IIPAIDOJ_00587 1.1e-113 ywnB S NAD(P)H-binding
IIPAIDOJ_00588 1.7e-64 ywnA K Transcriptional regulator
IIPAIDOJ_00589 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IIPAIDOJ_00590 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IIPAIDOJ_00591 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IIPAIDOJ_00592 3.8e-11 csbD K CsbD-like
IIPAIDOJ_00593 5.1e-84 ywmF S Peptidase M50
IIPAIDOJ_00594 7.9e-104 S response regulator aspartate phosphatase
IIPAIDOJ_00595 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IIPAIDOJ_00596 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IIPAIDOJ_00598 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
IIPAIDOJ_00599 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
IIPAIDOJ_00600 3.5e-175 spoIID D Stage II sporulation protein D
IIPAIDOJ_00601 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIPAIDOJ_00602 8.2e-134 ywmB S TATA-box binding
IIPAIDOJ_00603 1.3e-32 ywzB S membrane
IIPAIDOJ_00604 4.1e-86 ywmA
IIPAIDOJ_00605 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IIPAIDOJ_00606 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IIPAIDOJ_00607 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IIPAIDOJ_00608 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IIPAIDOJ_00609 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIPAIDOJ_00610 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IIPAIDOJ_00611 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIPAIDOJ_00612 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
IIPAIDOJ_00613 2.5e-62 atpI S ATP synthase
IIPAIDOJ_00614 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IIPAIDOJ_00615 1e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IIPAIDOJ_00616 7.2e-95 ywlG S Belongs to the UPF0340 family
IIPAIDOJ_00617 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
IIPAIDOJ_00618 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIPAIDOJ_00619 1.7e-91 mntP P Probably functions as a manganese efflux pump
IIPAIDOJ_00620 2.6e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IIPAIDOJ_00621 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
IIPAIDOJ_00622 6.1e-112 spoIIR S stage II sporulation protein R
IIPAIDOJ_00623 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
IIPAIDOJ_00625 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IIPAIDOJ_00626 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IIPAIDOJ_00627 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIPAIDOJ_00628 3.5e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IIPAIDOJ_00629 8.6e-160 ywkB S Membrane transport protein
IIPAIDOJ_00630 0.0 sfcA 1.1.1.38 C malic enzyme
IIPAIDOJ_00631 5.4e-104 tdk 2.7.1.21 F thymidine kinase
IIPAIDOJ_00632 1.1e-32 rpmE J Binds the 23S rRNA
IIPAIDOJ_00633 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IIPAIDOJ_00634 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
IIPAIDOJ_00635 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIPAIDOJ_00636 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IIPAIDOJ_00637 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
IIPAIDOJ_00638 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
IIPAIDOJ_00639 6e-91 ywjG S Domain of unknown function (DUF2529)
IIPAIDOJ_00640 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IIPAIDOJ_00641 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IIPAIDOJ_00642 2.2e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
IIPAIDOJ_00643 0.0 fadF C COG0247 Fe-S oxidoreductase
IIPAIDOJ_00644 4.4e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IIPAIDOJ_00645 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IIPAIDOJ_00646 2.7e-42 ywjC
IIPAIDOJ_00647 5.3e-95 ywjB H RibD C-terminal domain
IIPAIDOJ_00648 0.0 ywjA V ABC transporter
IIPAIDOJ_00649 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIPAIDOJ_00650 1.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
IIPAIDOJ_00651 1.1e-93 narJ 1.7.5.1 C nitrate reductase
IIPAIDOJ_00652 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
IIPAIDOJ_00653 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IIPAIDOJ_00654 7e-86 arfM T cyclic nucleotide binding
IIPAIDOJ_00655 1.7e-139 ywiC S YwiC-like protein
IIPAIDOJ_00656 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
IIPAIDOJ_00657 1.3e-213 narK P COG2223 Nitrate nitrite transporter
IIPAIDOJ_00658 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IIPAIDOJ_00659 4.7e-73 ywiB S protein conserved in bacteria
IIPAIDOJ_00660 1e-07 S Bacteriocin subtilosin A
IIPAIDOJ_00661 1.3e-270 C Fe-S oxidoreductases
IIPAIDOJ_00663 3.3e-132 cbiO V ABC transporter
IIPAIDOJ_00664 7.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
IIPAIDOJ_00665 3.6e-216 2.7.1.26, 2.7.7.2 L Peptidase, M16
IIPAIDOJ_00666 1.5e-247 L Peptidase, M16
IIPAIDOJ_00668 1.4e-243 ywhL CO amine dehydrogenase activity
IIPAIDOJ_00669 5.6e-197 ywhK CO amine dehydrogenase activity
IIPAIDOJ_00670 2.3e-79 S aspartate phosphatase
IIPAIDOJ_00673 1.7e-20
IIPAIDOJ_00676 1.4e-57 V ATPases associated with a variety of cellular activities
IIPAIDOJ_00678 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
IIPAIDOJ_00679 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IIPAIDOJ_00680 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IIPAIDOJ_00681 2.2e-93 ywhD S YwhD family
IIPAIDOJ_00682 5.1e-119 ywhC S Peptidase family M50
IIPAIDOJ_00683 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
IIPAIDOJ_00684 3.3e-71 ywhA K Transcriptional regulator
IIPAIDOJ_00685 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIPAIDOJ_00687 1.4e-235 mmr U Major Facilitator Superfamily
IIPAIDOJ_00688 6.9e-78 yffB K Transcriptional regulator
IIPAIDOJ_00689 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
IIPAIDOJ_00690 7.4e-255 ywfO S COG1078 HD superfamily phosphohydrolases
IIPAIDOJ_00691 3.1e-36 ywzC S Belongs to the UPF0741 family
IIPAIDOJ_00692 1e-110 rsfA_1
IIPAIDOJ_00693 2.2e-157 ywfM EG EamA-like transporter family
IIPAIDOJ_00694 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IIPAIDOJ_00695 7.1e-156 cysL K Transcriptional regulator
IIPAIDOJ_00696 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
IIPAIDOJ_00697 3.3e-146 ywfI C May function as heme-dependent peroxidase
IIPAIDOJ_00698 7.5e-138 IQ Enoyl-(Acyl carrier protein) reductase
IIPAIDOJ_00699 7.3e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
IIPAIDOJ_00700 7.3e-209 bacE EGP Major facilitator Superfamily
IIPAIDOJ_00701 2e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IIPAIDOJ_00702 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIPAIDOJ_00703 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IIPAIDOJ_00704 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IIPAIDOJ_00705 6e-206 ywfA EGP Major facilitator Superfamily
IIPAIDOJ_00706 7.4e-250 lysP E amino acid
IIPAIDOJ_00707 0.0 rocB E arginine degradation protein
IIPAIDOJ_00708 6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IIPAIDOJ_00709 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IIPAIDOJ_00710 1.2e-77
IIPAIDOJ_00711 1.3e-86 spsL 5.1.3.13 M Spore Coat
IIPAIDOJ_00712 4.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IIPAIDOJ_00713 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IIPAIDOJ_00714 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IIPAIDOJ_00715 3.3e-186 spsG M Spore Coat
IIPAIDOJ_00716 2.4e-130 spsF M Spore Coat
IIPAIDOJ_00717 3.5e-213 spsE 2.5.1.56 M acid synthase
IIPAIDOJ_00718 4.9e-162 spsD 2.3.1.210 K Spore Coat
IIPAIDOJ_00719 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
IIPAIDOJ_00720 5.6e-269 spsB M Capsule polysaccharide biosynthesis protein
IIPAIDOJ_00721 2.6e-143 spsA M Spore Coat
IIPAIDOJ_00722 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IIPAIDOJ_00723 4.3e-59 ywdK S small membrane protein
IIPAIDOJ_00724 3.7e-238 ywdJ F Xanthine uracil
IIPAIDOJ_00725 1.1e-47 ywdI S Family of unknown function (DUF5327)
IIPAIDOJ_00726 3.8e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IIPAIDOJ_00727 3.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IIPAIDOJ_00728 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
IIPAIDOJ_00730 4.9e-111 ywdD
IIPAIDOJ_00731 1.3e-57 pex K Transcriptional regulator PadR-like family
IIPAIDOJ_00732 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IIPAIDOJ_00733 2e-28 ywdA
IIPAIDOJ_00734 1.7e-289 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
IIPAIDOJ_00735 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IIPAIDOJ_00736 1.7e-137 focA P Formate/nitrite transporter
IIPAIDOJ_00737 7e-150 sacT K transcriptional antiterminator
IIPAIDOJ_00739 0.0 vpr O Belongs to the peptidase S8 family
IIPAIDOJ_00740 7.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIPAIDOJ_00741 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
IIPAIDOJ_00742 2.9e-189 rodA D Belongs to the SEDS family
IIPAIDOJ_00743 2.2e-202 S Acetyltransferase
IIPAIDOJ_00744 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
IIPAIDOJ_00745 1e-63 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IIPAIDOJ_00746 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IIPAIDOJ_00747 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IIPAIDOJ_00748 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IIPAIDOJ_00749 1e-35 ywzA S membrane
IIPAIDOJ_00750 1.4e-297 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IIPAIDOJ_00751 4.5e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IIPAIDOJ_00752 9.5e-60 gtcA S GtrA-like protein
IIPAIDOJ_00753 2.2e-122 ywcC K transcriptional regulator
IIPAIDOJ_00755 9.8e-49 ywcB S Protein of unknown function, DUF485
IIPAIDOJ_00756 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IIPAIDOJ_00757 3.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IIPAIDOJ_00758 6.4e-224 ywbN P Dyp-type peroxidase family protein
IIPAIDOJ_00759 2.1e-184 ycdO P periplasmic lipoprotein involved in iron transport
IIPAIDOJ_00760 1.3e-252 P COG0672 High-affinity Fe2 Pb2 permease
IIPAIDOJ_00761 1.4e-111 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IIPAIDOJ_00762 3.4e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IIPAIDOJ_00763 4.3e-153 ywbI K Transcriptional regulator
IIPAIDOJ_00764 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IIPAIDOJ_00765 2.3e-111 ywbG M effector of murein hydrolase
IIPAIDOJ_00766 3.1e-207 ywbF EGP Major facilitator Superfamily
IIPAIDOJ_00767 3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
IIPAIDOJ_00768 5.4e-220 ywbD 2.1.1.191 J Methyltransferase
IIPAIDOJ_00769 9.9e-67 ywbC 4.4.1.5 E glyoxalase
IIPAIDOJ_00770 1.5e-118 ywbB S Protein of unknown function (DUF2711)
IIPAIDOJ_00771 6.6e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPAIDOJ_00772 1.9e-270 epr 3.4.21.62 O Belongs to the peptidase S8 family
IIPAIDOJ_00773 2.6e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IIPAIDOJ_00774 4e-153 sacY K transcriptional antiterminator
IIPAIDOJ_00775 4.5e-168 gspA M General stress
IIPAIDOJ_00776 2.5e-124 ywaF S Integral membrane protein
IIPAIDOJ_00777 4e-87 ywaE K Transcriptional regulator
IIPAIDOJ_00778 1.3e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IIPAIDOJ_00779 4.4e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
IIPAIDOJ_00780 1.4e-92 K Helix-turn-helix XRE-family like proteins
IIPAIDOJ_00781 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
IIPAIDOJ_00782 5.7e-129 ynfM EGP Major facilitator Superfamily
IIPAIDOJ_00783 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
IIPAIDOJ_00784 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
IIPAIDOJ_00785 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
IIPAIDOJ_00786 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPAIDOJ_00787 1.2e-232 dltB M membrane protein involved in D-alanine export
IIPAIDOJ_00788 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPAIDOJ_00789 6.7e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IIPAIDOJ_00790 4.7e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPAIDOJ_00791 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IIPAIDOJ_00792 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IIPAIDOJ_00793 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
IIPAIDOJ_00794 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPAIDOJ_00795 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
IIPAIDOJ_00796 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
IIPAIDOJ_00797 1.1e-19 yxzF
IIPAIDOJ_00798 5e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IIPAIDOJ_00799 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IIPAIDOJ_00800 3e-210 yxlH EGP Major facilitator Superfamily
IIPAIDOJ_00801 5.2e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IIPAIDOJ_00802 4.8e-165 yxlF V ABC transporter, ATP-binding protein
IIPAIDOJ_00803 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
IIPAIDOJ_00804 1.4e-30
IIPAIDOJ_00805 3.9e-48 yxlC S Family of unknown function (DUF5345)
IIPAIDOJ_00806 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
IIPAIDOJ_00807 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
IIPAIDOJ_00808 1.2e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IIPAIDOJ_00809 0.0 cydD V ATP-binding protein
IIPAIDOJ_00810 1.2e-310 cydD V ATP-binding
IIPAIDOJ_00811 1.1e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
IIPAIDOJ_00812 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
IIPAIDOJ_00813 4.2e-229 cimH C COG3493 Na citrate symporter
IIPAIDOJ_00814 0.0 3.4.24.84 O Peptidase family M48
IIPAIDOJ_00816 3.1e-153 yxkH G Polysaccharide deacetylase
IIPAIDOJ_00817 5.9e-205 msmK P Belongs to the ABC transporter superfamily
IIPAIDOJ_00818 3.5e-163 lrp QT PucR C-terminal helix-turn-helix domain
IIPAIDOJ_00819 8.8e-273 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IIPAIDOJ_00820 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IIPAIDOJ_00821 1.4e-73 yxkC S Domain of unknown function (DUF4352)
IIPAIDOJ_00822 3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IIPAIDOJ_00823 2e-77 S Protein of unknown function (DUF1453)
IIPAIDOJ_00824 6.6e-189 yxjM T Signal transduction histidine kinase
IIPAIDOJ_00825 3.7e-114 K helix_turn_helix, Lux Regulon
IIPAIDOJ_00826 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IIPAIDOJ_00829 4.6e-85 yxjI S LURP-one-related
IIPAIDOJ_00830 1.6e-218 yxjG 2.1.1.14 E Methionine synthase
IIPAIDOJ_00831 3.7e-218 yxjG 2.1.1.14 E Methionine synthase
IIPAIDOJ_00832 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IIPAIDOJ_00833 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IIPAIDOJ_00834 5.3e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IIPAIDOJ_00835 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
IIPAIDOJ_00836 1.9e-141 rlmA 2.1.1.187 Q Methyltransferase domain
IIPAIDOJ_00837 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IIPAIDOJ_00838 1e-103 T Domain of unknown function (DUF4163)
IIPAIDOJ_00839 1.6e-45 yxiS
IIPAIDOJ_00840 4.6e-171 L DNA synthesis involved in DNA repair
IIPAIDOJ_00841 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
IIPAIDOJ_00842 6.6e-224 citH C Citrate transporter
IIPAIDOJ_00843 1.1e-143 exoK GH16 M licheninase activity
IIPAIDOJ_00844 3.1e-150 licT K transcriptional antiterminator
IIPAIDOJ_00845 1.7e-93
IIPAIDOJ_00846 7.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
IIPAIDOJ_00847 2.8e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IIPAIDOJ_00848 2.5e-214 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
IIPAIDOJ_00849 5.5e-53 padR K Transcriptional regulator PadR-like family
IIPAIDOJ_00850 1.3e-61 S Protein of unknown function (DUF2812)
IIPAIDOJ_00853 0.0 wapA M COG3209 Rhs family protein
IIPAIDOJ_00854 2.3e-165 yxxF EG EamA-like transporter family
IIPAIDOJ_00855 5.4e-72 yxiE T Belongs to the universal stress protein A family
IIPAIDOJ_00856 4.6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPAIDOJ_00857 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IIPAIDOJ_00858 4.1e-21 S Immunity protein 8
IIPAIDOJ_00859 2.1e-211 S nuclease activity
IIPAIDOJ_00860 1.4e-38 yxiC S Family of unknown function (DUF5344)
IIPAIDOJ_00861 2.3e-20 S Domain of unknown function (DUF5082)
IIPAIDOJ_00862 0.0 L HKD family nuclease
IIPAIDOJ_00863 3.5e-59 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IIPAIDOJ_00864 1e-165 L Protein of unknown function (DUF2726)
IIPAIDOJ_00865 1.3e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IIPAIDOJ_00866 1.9e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IIPAIDOJ_00867 6.8e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
IIPAIDOJ_00868 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IIPAIDOJ_00869 2.4e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
IIPAIDOJ_00870 1.1e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IIPAIDOJ_00871 2.3e-251 lysP E amino acid
IIPAIDOJ_00872 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
IIPAIDOJ_00873 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IIPAIDOJ_00874 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IIPAIDOJ_00875 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IIPAIDOJ_00876 9.7e-152 yxxB S Domain of Unknown Function (DUF1206)
IIPAIDOJ_00877 9.2e-198 eutH E Ethanolamine utilisation protein, EutH
IIPAIDOJ_00878 8.6e-251 yxeQ S MmgE/PrpD family
IIPAIDOJ_00879 5.5e-214 yxeP 3.5.1.47 E hydrolase activity
IIPAIDOJ_00880 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
IIPAIDOJ_00881 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
IIPAIDOJ_00882 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
IIPAIDOJ_00883 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIPAIDOJ_00884 7e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIPAIDOJ_00885 2e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IIPAIDOJ_00886 3.1e-150 yidA S hydrolases of the HAD superfamily
IIPAIDOJ_00889 1.3e-20 yxeE
IIPAIDOJ_00890 5.6e-16 yxeD
IIPAIDOJ_00891 8.5e-69
IIPAIDOJ_00892 6.6e-176 fhuD P ABC transporter
IIPAIDOJ_00893 1.3e-57 yxeA S Protein of unknown function (DUF1093)
IIPAIDOJ_00894 0.0 yxdM V ABC transporter (permease)
IIPAIDOJ_00895 3.7e-137 yxdL V ABC transporter, ATP-binding protein
IIPAIDOJ_00896 6.9e-181 T PhoQ Sensor
IIPAIDOJ_00897 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_00898 6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IIPAIDOJ_00899 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IIPAIDOJ_00900 3e-167 iolH G Xylose isomerase-like TIM barrel
IIPAIDOJ_00901 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IIPAIDOJ_00902 9.6e-234 iolF EGP Major facilitator Superfamily
IIPAIDOJ_00903 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IIPAIDOJ_00904 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IIPAIDOJ_00905 8.7e-176 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IIPAIDOJ_00906 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IIPAIDOJ_00907 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IIPAIDOJ_00908 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
IIPAIDOJ_00909 8.3e-176 iolS C Aldo keto reductase
IIPAIDOJ_00911 5.4e-47 yxcD S Protein of unknown function (DUF2653)
IIPAIDOJ_00912 2.5e-90 S CGNR zinc finger
IIPAIDOJ_00913 8.9e-79 T HPP family
IIPAIDOJ_00914 1.5e-245 csbC EGP Major facilitator Superfamily
IIPAIDOJ_00915 0.0 htpG O Molecular chaperone. Has ATPase activity
IIPAIDOJ_00917 8.2e-151 IQ Enoyl-(Acyl carrier protein) reductase
IIPAIDOJ_00918 6.2e-197 yxbF K Bacterial regulatory proteins, tetR family
IIPAIDOJ_00919 1.7e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IIPAIDOJ_00921 3.7e-91 S PQQ-like domain
IIPAIDOJ_00922 1.1e-63 S Family of unknown function (DUF5391)
IIPAIDOJ_00923 1.4e-75 yxaI S membrane protein domain
IIPAIDOJ_00924 4.6e-227 P Protein of unknown function (DUF418)
IIPAIDOJ_00925 3.2e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
IIPAIDOJ_00926 4.6e-100 yxaF K Transcriptional regulator
IIPAIDOJ_00927 4.4e-197 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPAIDOJ_00928 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
IIPAIDOJ_00929 5.2e-50 S LrgA family
IIPAIDOJ_00930 2.6e-118 yxaC M effector of murein hydrolase
IIPAIDOJ_00931 1.3e-190 yxaB GM Polysaccharide pyruvyl transferase
IIPAIDOJ_00932 2.8e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IIPAIDOJ_00933 7.3e-127 gntR K transcriptional
IIPAIDOJ_00934 5.6e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
IIPAIDOJ_00935 7.7e-231 gntP EG COG2610 H gluconate symporter and related permeases
IIPAIDOJ_00936 1.1e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IIPAIDOJ_00937 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
IIPAIDOJ_00938 1.6e-285 ahpF O Alkyl hydroperoxide reductase
IIPAIDOJ_00939 8.1e-188 wgaE S Polysaccharide pyruvyl transferase
IIPAIDOJ_00940 2.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPAIDOJ_00941 1.1e-39 bglF G phosphotransferase system
IIPAIDOJ_00942 3.3e-124 yydK K Transcriptional regulator
IIPAIDOJ_00943 7.6e-13
IIPAIDOJ_00944 8e-118 S ABC-2 family transporter protein
IIPAIDOJ_00945 1.6e-109 prrC P ABC transporter
IIPAIDOJ_00946 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
IIPAIDOJ_00947 1.5e-15 2.7.7.9 K Helix-turn-helix XRE-family like proteins
IIPAIDOJ_00948 3.6e-107 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IIPAIDOJ_00949 2.5e-110 K NAD+ binding
IIPAIDOJ_00950 1.6e-114 D AAA domain
IIPAIDOJ_00951 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IIPAIDOJ_00952 1.1e-09 S YyzF-like protein
IIPAIDOJ_00953 4.4e-68
IIPAIDOJ_00954 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IIPAIDOJ_00956 1.7e-30 yycQ S Protein of unknown function (DUF2651)
IIPAIDOJ_00957 4.9e-210 yycP
IIPAIDOJ_00958 1.3e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IIPAIDOJ_00959 1.1e-83 yycN 2.3.1.128 K Acetyltransferase
IIPAIDOJ_00960 1.5e-187 S aspartate phosphatase
IIPAIDOJ_00962 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
IIPAIDOJ_00963 1e-254 rocE E amino acid
IIPAIDOJ_00964 3.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
IIPAIDOJ_00965 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IIPAIDOJ_00966 6.7e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
IIPAIDOJ_00967 2.2e-93 K PFAM response regulator receiver
IIPAIDOJ_00968 1.2e-73 S Peptidase propeptide and YPEB domain
IIPAIDOJ_00969 3.8e-34 S Peptidase propeptide and YPEB domain
IIPAIDOJ_00970 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IIPAIDOJ_00971 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IIPAIDOJ_00972 7.3e-155 yycI S protein conserved in bacteria
IIPAIDOJ_00973 1.4e-256 yycH S protein conserved in bacteria
IIPAIDOJ_00974 0.0 vicK 2.7.13.3 T Histidine kinase
IIPAIDOJ_00975 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_00980 3.9e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IIPAIDOJ_00981 2e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIPAIDOJ_00982 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IIPAIDOJ_00983 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
IIPAIDOJ_00985 1.9e-15 yycC K YycC-like protein
IIPAIDOJ_00986 2.5e-220 yeaN P COG2807 Cyanate permease
IIPAIDOJ_00987 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIPAIDOJ_00988 2.2e-73 rplI J binds to the 23S rRNA
IIPAIDOJ_00989 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IIPAIDOJ_00990 1.9e-159 yybS S membrane
IIPAIDOJ_00992 3.9e-84 cotF M Spore coat protein
IIPAIDOJ_00993 1.7e-66 ydeP3 K Transcriptional regulator
IIPAIDOJ_00994 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
IIPAIDOJ_00995 5.6e-61
IIPAIDOJ_00997 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
IIPAIDOJ_00998 1.7e-110 K TipAS antibiotic-recognition domain
IIPAIDOJ_00999 6.9e-123
IIPAIDOJ_01000 2.3e-66 yybH S SnoaL-like domain
IIPAIDOJ_01001 1.4e-121 yybG S Pentapeptide repeat-containing protein
IIPAIDOJ_01002 2.3e-218 ynfM EGP Major facilitator Superfamily
IIPAIDOJ_01003 5.8e-163 yybE K Transcriptional regulator
IIPAIDOJ_01004 2.5e-77 yjcF S Acetyltransferase (GNAT) domain
IIPAIDOJ_01005 4.3e-75 yybC
IIPAIDOJ_01006 4e-124 S Metallo-beta-lactamase superfamily
IIPAIDOJ_01007 1.6e-76 yybA 2.3.1.57 K transcriptional
IIPAIDOJ_01008 1.4e-69 yjcF S Acetyltransferase (GNAT) domain
IIPAIDOJ_01009 7.4e-93 yyaS S Membrane
IIPAIDOJ_01011 1.7e-151 eaeH M Domain of Unknown Function (DUF1259)
IIPAIDOJ_01012 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
IIPAIDOJ_01013 3.4e-166 yyaK S CAAX protease self-immunity
IIPAIDOJ_01014 1.8e-243 EGP Major facilitator superfamily
IIPAIDOJ_01015 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
IIPAIDOJ_01016 8.4e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIPAIDOJ_01017 9.9e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
IIPAIDOJ_01018 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
IIPAIDOJ_01019 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IIPAIDOJ_01020 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIPAIDOJ_01021 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
IIPAIDOJ_01022 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IIPAIDOJ_01023 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IIPAIDOJ_01024 2.3e-33 yyzM S protein conserved in bacteria
IIPAIDOJ_01025 8.1e-177 yyaD S Membrane
IIPAIDOJ_01026 1.6e-111 yyaC S Sporulation protein YyaC
IIPAIDOJ_01027 2.1e-149 spo0J K Belongs to the ParB family
IIPAIDOJ_01028 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
IIPAIDOJ_01029 9.6e-74 S Bacterial PH domain
IIPAIDOJ_01030 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IIPAIDOJ_01031 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IIPAIDOJ_01032 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IIPAIDOJ_01033 8.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IIPAIDOJ_01034 6.5e-108 jag S single-stranded nucleic acid binding R3H
IIPAIDOJ_01035 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIPAIDOJ_01036 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IIPAIDOJ_01037 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IIPAIDOJ_01038 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IIPAIDOJ_01039 2.4e-33 yaaA S S4 domain
IIPAIDOJ_01040 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IIPAIDOJ_01041 1.8e-37 yaaB S Domain of unknown function (DUF370)
IIPAIDOJ_01042 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIPAIDOJ_01043 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIPAIDOJ_01048 7.8e-08
IIPAIDOJ_01056 2e-08
IIPAIDOJ_01060 1.7e-142 spo0M S COG4326 Sporulation control protein
IIPAIDOJ_01061 1.2e-26
IIPAIDOJ_01062 3.9e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
IIPAIDOJ_01063 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IIPAIDOJ_01064 1.3e-262 ygaK C Berberine and berberine like
IIPAIDOJ_01066 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IIPAIDOJ_01067 1.5e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IIPAIDOJ_01068 4.3e-170 ssuA M Sulfonate ABC transporter
IIPAIDOJ_01069 3.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IIPAIDOJ_01070 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
IIPAIDOJ_01072 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIPAIDOJ_01073 1.7e-76 ygaO
IIPAIDOJ_01074 4.4e-29 K Transcriptional regulator
IIPAIDOJ_01076 8.7e-113 yhzB S B3/4 domain
IIPAIDOJ_01077 6e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IIPAIDOJ_01078 4.8e-176 yhbB S Putative amidase domain
IIPAIDOJ_01079 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IIPAIDOJ_01080 1.1e-107 yhbD K Protein of unknown function (DUF4004)
IIPAIDOJ_01081 1.4e-58 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
IIPAIDOJ_01082 3e-69 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
IIPAIDOJ_01083 0.0 prkA T Ser protein kinase
IIPAIDOJ_01084 2.5e-225 yhbH S Belongs to the UPF0229 family
IIPAIDOJ_01086 2.2e-76 yhbI K DNA-binding transcription factor activity
IIPAIDOJ_01087 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
IIPAIDOJ_01088 3.1e-271 yhcA EGP Major facilitator Superfamily
IIPAIDOJ_01089 1.8e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
IIPAIDOJ_01090 2.8e-37 yhcC
IIPAIDOJ_01091 3.5e-55
IIPAIDOJ_01092 1.9e-59 yhcF K Transcriptional regulator
IIPAIDOJ_01093 4e-122 yhcG V ABC transporter, ATP-binding protein
IIPAIDOJ_01094 7.7e-166 yhcH V ABC transporter, ATP-binding protein
IIPAIDOJ_01095 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IIPAIDOJ_01096 1e-30 cspB K Cold-shock protein
IIPAIDOJ_01097 8.3e-151 metQ M Belongs to the nlpA lipoprotein family
IIPAIDOJ_01098 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
IIPAIDOJ_01099 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIPAIDOJ_01100 5.4e-40 yhcM
IIPAIDOJ_01101 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IIPAIDOJ_01102 2.5e-167 yhcP
IIPAIDOJ_01103 5.2e-100 yhcQ M Spore coat protein
IIPAIDOJ_01104 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
IIPAIDOJ_01105 6e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
IIPAIDOJ_01106 6.2e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IIPAIDOJ_01107 2.1e-67 yhcU S Family of unknown function (DUF5365)
IIPAIDOJ_01108 9.9e-68 yhcV S COG0517 FOG CBS domain
IIPAIDOJ_01109 1e-119 yhcW 5.4.2.6 S hydrolase
IIPAIDOJ_01110 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IIPAIDOJ_01111 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IIPAIDOJ_01112 1.2e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IIPAIDOJ_01113 4.3e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
IIPAIDOJ_01114 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IIPAIDOJ_01115 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IIPAIDOJ_01116 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IIPAIDOJ_01117 4e-212 yhcY 2.7.13.3 T Histidine kinase
IIPAIDOJ_01118 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIPAIDOJ_01119 6.1e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
IIPAIDOJ_01120 1.2e-38 yhdB S YhdB-like protein
IIPAIDOJ_01121 1.3e-51 yhdC S Protein of unknown function (DUF3889)
IIPAIDOJ_01122 1.9e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IIPAIDOJ_01123 5.1e-75 nsrR K Transcriptional regulator
IIPAIDOJ_01124 1.6e-237 ygxB M Conserved TM helix
IIPAIDOJ_01125 2.1e-276 ycgB S Stage V sporulation protein R
IIPAIDOJ_01126 7e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
IIPAIDOJ_01127 1.5e-138 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IIPAIDOJ_01128 3.8e-162 citR K Transcriptional regulator
IIPAIDOJ_01129 8.5e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
IIPAIDOJ_01130 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIPAIDOJ_01131 3.4e-250 yhdG E amino acid
IIPAIDOJ_01132 3.3e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IIPAIDOJ_01133 1.5e-266 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIPAIDOJ_01134 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIPAIDOJ_01135 8.1e-45 yhdK S Sigma-M inhibitor protein
IIPAIDOJ_01136 2.5e-200 yhdL S Sigma factor regulator N-terminal
IIPAIDOJ_01137 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
IIPAIDOJ_01138 1.7e-190 yhdN C Aldo keto reductase
IIPAIDOJ_01139 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IIPAIDOJ_01140 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IIPAIDOJ_01141 4.7e-74 cueR K transcriptional
IIPAIDOJ_01142 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
IIPAIDOJ_01143 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
IIPAIDOJ_01144 7.1e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIPAIDOJ_01145 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIPAIDOJ_01146 8.9e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IIPAIDOJ_01148 1.7e-183 yhdY M Mechanosensitive ion channel
IIPAIDOJ_01149 5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IIPAIDOJ_01150 2.1e-146 yheN G deacetylase
IIPAIDOJ_01151 9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IIPAIDOJ_01152 3.3e-229 nhaC C Na H antiporter
IIPAIDOJ_01153 3.4e-84 nhaX T Belongs to the universal stress protein A family
IIPAIDOJ_01154 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
IIPAIDOJ_01155 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
IIPAIDOJ_01156 1.5e-109 yheG GM NAD(P)H-binding
IIPAIDOJ_01157 6.3e-28 sspB S spore protein
IIPAIDOJ_01158 1.3e-36 yheE S Family of unknown function (DUF5342)
IIPAIDOJ_01159 3.3e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
IIPAIDOJ_01160 4.3e-216 yheC HJ YheC/D like ATP-grasp
IIPAIDOJ_01161 2.2e-202 yheB S Belongs to the UPF0754 family
IIPAIDOJ_01162 9.5e-48 yheA S Belongs to the UPF0342 family
IIPAIDOJ_01163 2.2e-204 yhaZ L DNA alkylation repair enzyme
IIPAIDOJ_01164 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
IIPAIDOJ_01165 1.9e-291 hemZ H coproporphyrinogen III oxidase
IIPAIDOJ_01166 1.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
IIPAIDOJ_01167 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
IIPAIDOJ_01169 3.5e-130 yhaR 5.3.3.18 I enoyl-CoA hydratase
IIPAIDOJ_01170 2.4e-26 S YhzD-like protein
IIPAIDOJ_01171 5.2e-167 yhaQ S ABC transporter, ATP-binding protein
IIPAIDOJ_01172 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
IIPAIDOJ_01173 1.9e-220 yhaO L DNA repair exonuclease
IIPAIDOJ_01174 0.0 yhaN L AAA domain
IIPAIDOJ_01175 5.8e-177 yhaM L Shows a 3'-5' exoribonuclease activity
IIPAIDOJ_01176 1.6e-21 yhaL S Sporulation protein YhaL
IIPAIDOJ_01177 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IIPAIDOJ_01178 1.1e-89 yhaK S Putative zincin peptidase
IIPAIDOJ_01179 1.3e-54 yhaI S Protein of unknown function (DUF1878)
IIPAIDOJ_01180 1e-113 hpr K Negative regulator of protease production and sporulation
IIPAIDOJ_01181 7e-39 yhaH S YtxH-like protein
IIPAIDOJ_01182 5.4e-21
IIPAIDOJ_01183 3.6e-80 trpP S Tryptophan transporter TrpP
IIPAIDOJ_01184 2.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IIPAIDOJ_01185 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IIPAIDOJ_01186 4.6e-137 ecsA V transporter (ATP-binding protein)
IIPAIDOJ_01187 1.7e-213 ecsB U ABC transporter
IIPAIDOJ_01188 3.4e-113 ecsC S EcsC protein family
IIPAIDOJ_01189 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IIPAIDOJ_01190 2.7e-231 yhfA C membrane
IIPAIDOJ_01191 4.3e-31 1.15.1.2 C Rubrerythrin
IIPAIDOJ_01192 7.1e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IIPAIDOJ_01193 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IIPAIDOJ_01194 5.9e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IIPAIDOJ_01195 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IIPAIDOJ_01196 2.9e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IIPAIDOJ_01197 1e-99 yhgD K Transcriptional regulator
IIPAIDOJ_01198 4.6e-215 yhgE S YhgE Pip N-terminal domain protein
IIPAIDOJ_01199 1.3e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIPAIDOJ_01200 3.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
IIPAIDOJ_01201 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
IIPAIDOJ_01202 1.4e-71 3.4.13.21 S ASCH
IIPAIDOJ_01203 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIPAIDOJ_01204 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IIPAIDOJ_01205 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
IIPAIDOJ_01206 2.9e-111 yhfK GM NmrA-like family
IIPAIDOJ_01207 2.7e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IIPAIDOJ_01208 1.3e-64 yhfM
IIPAIDOJ_01209 2.7e-241 yhfN 3.4.24.84 O Peptidase M48
IIPAIDOJ_01210 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
IIPAIDOJ_01211 5e-78 VY92_01935 K acetyltransferase
IIPAIDOJ_01212 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
IIPAIDOJ_01213 4.3e-159 yfmC M Periplasmic binding protein
IIPAIDOJ_01214 3.5e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IIPAIDOJ_01215 1.4e-195 vraB 2.3.1.9 I Belongs to the thiolase family
IIPAIDOJ_01216 2.3e-273 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IIPAIDOJ_01217 1.9e-90 bioY S BioY family
IIPAIDOJ_01218 2.7e-180 hemAT NT chemotaxis protein
IIPAIDOJ_01219 8.8e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
IIPAIDOJ_01220 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIPAIDOJ_01221 1.3e-32 yhzC S IDEAL
IIPAIDOJ_01222 4.2e-109 comK K Competence transcription factor
IIPAIDOJ_01223 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
IIPAIDOJ_01224 1.1e-40 yhjA S Excalibur calcium-binding domain
IIPAIDOJ_01225 1.7e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IIPAIDOJ_01226 4.5e-26 yhjC S Protein of unknown function (DUF3311)
IIPAIDOJ_01227 1.6e-58 yhjD
IIPAIDOJ_01228 9.1e-110 yhjE S SNARE associated Golgi protein
IIPAIDOJ_01229 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
IIPAIDOJ_01230 2.1e-277 yhjG CH FAD binding domain
IIPAIDOJ_01231 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
IIPAIDOJ_01234 2.5e-212 glcP G Major Facilitator Superfamily
IIPAIDOJ_01235 7.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
IIPAIDOJ_01236 5.8e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
IIPAIDOJ_01237 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
IIPAIDOJ_01238 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
IIPAIDOJ_01239 4.2e-201 abrB S membrane
IIPAIDOJ_01240 4.9e-213 EGP Transmembrane secretion effector
IIPAIDOJ_01241 0.0 S Sugar transport-related sRNA regulator N-term
IIPAIDOJ_01242 6.4e-78 yhjR S Rubrerythrin
IIPAIDOJ_01243 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
IIPAIDOJ_01244 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IIPAIDOJ_01245 1.4e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IIPAIDOJ_01246 0.0 sbcC L COG0419 ATPase involved in DNA repair
IIPAIDOJ_01247 1.1e-49 yisB V COG1403 Restriction endonuclease
IIPAIDOJ_01248 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
IIPAIDOJ_01249 5.3e-63 gerPE S Spore germination protein GerPE
IIPAIDOJ_01250 1.1e-23 gerPD S Spore germination protein
IIPAIDOJ_01251 5.3e-54 gerPC S Spore germination protein
IIPAIDOJ_01252 4e-34 gerPB S cell differentiation
IIPAIDOJ_01253 1.9e-33 gerPA S Spore germination protein
IIPAIDOJ_01255 1.5e-22 yisI S Spo0E like sporulation regulatory protein
IIPAIDOJ_01256 6.8e-170 cotH M Spore Coat
IIPAIDOJ_01257 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IIPAIDOJ_01258 3.9e-57 yisL S UPF0344 protein
IIPAIDOJ_01259 0.0 wprA O Belongs to the peptidase S8 family
IIPAIDOJ_01260 1.8e-101 yisN S Protein of unknown function (DUF2777)
IIPAIDOJ_01261 0.0 asnO 6.3.5.4 E Asparagine synthase
IIPAIDOJ_01262 9.3e-115 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
IIPAIDOJ_01263 1.5e-242 yisQ V Mate efflux family protein
IIPAIDOJ_01264 1.2e-160 yisR K Transcriptional regulator
IIPAIDOJ_01265 3.2e-181 purR K helix_turn _helix lactose operon repressor
IIPAIDOJ_01266 2.3e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
IIPAIDOJ_01267 7e-92 yisT S DinB family
IIPAIDOJ_01268 1.2e-106 argO S Lysine exporter protein LysE YggA
IIPAIDOJ_01269 7.1e-127 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIPAIDOJ_01270 4.4e-97 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIPAIDOJ_01271 4e-36 mcbG S Pentapeptide repeats (9 copies)
IIPAIDOJ_01272 1.2e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IIPAIDOJ_01273 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
IIPAIDOJ_01274 1.1e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
IIPAIDOJ_01275 2.1e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
IIPAIDOJ_01276 2.4e-119 comB 3.1.3.71 H Belongs to the ComB family
IIPAIDOJ_01277 5.4e-141 yitD 4.4.1.19 S synthase
IIPAIDOJ_01278 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IIPAIDOJ_01279 3.9e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IIPAIDOJ_01280 1.5e-228 yitG EGP Major facilitator Superfamily
IIPAIDOJ_01281 2e-152 yitH K Acetyltransferase (GNAT) domain
IIPAIDOJ_01282 2.1e-71 yjcF S Acetyltransferase (GNAT) domain
IIPAIDOJ_01283 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IIPAIDOJ_01284 1.5e-54 yajQ S Belongs to the UPF0234 family
IIPAIDOJ_01285 1.3e-159 cvfB S protein conserved in bacteria
IIPAIDOJ_01286 8.5e-94
IIPAIDOJ_01287 2.8e-171
IIPAIDOJ_01288 7.6e-97 S Sporulation delaying protein SdpA
IIPAIDOJ_01289 1.5e-58 K Transcriptional regulator PadR-like family
IIPAIDOJ_01290 1e-94
IIPAIDOJ_01291 1.4e-44 yitR S Domain of unknown function (DUF3784)
IIPAIDOJ_01292 2.7e-307 nprB 3.4.24.28 E Peptidase M4
IIPAIDOJ_01293 2.5e-158 yitS S protein conserved in bacteria
IIPAIDOJ_01294 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
IIPAIDOJ_01295 5e-73 ipi S Intracellular proteinase inhibitor
IIPAIDOJ_01296 1.5e-26 S Protein of unknown function (DUF3813)
IIPAIDOJ_01298 4.1e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IIPAIDOJ_01299 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IIPAIDOJ_01300 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
IIPAIDOJ_01301 1.5e-22 pilT S Proteolipid membrane potential modulator
IIPAIDOJ_01302 4.9e-268 yitY C D-arabinono-1,4-lactone oxidase
IIPAIDOJ_01303 3.4e-89 norB G Major Facilitator Superfamily
IIPAIDOJ_01304 5.6e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IIPAIDOJ_01305 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IIPAIDOJ_01306 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IIPAIDOJ_01307 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IIPAIDOJ_01308 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IIPAIDOJ_01309 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
IIPAIDOJ_01310 8.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IIPAIDOJ_01311 9.5e-28 yjzC S YjzC-like protein
IIPAIDOJ_01312 2.3e-16 yjzD S Protein of unknown function (DUF2929)
IIPAIDOJ_01313 6.2e-142 yjaU I carboxylic ester hydrolase activity
IIPAIDOJ_01314 9e-101 yjaV
IIPAIDOJ_01315 2.5e-183 med S Transcriptional activator protein med
IIPAIDOJ_01316 7.3e-26 comZ S ComZ
IIPAIDOJ_01317 5e-21 yjzB
IIPAIDOJ_01318 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIPAIDOJ_01319 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIPAIDOJ_01320 1.2e-148 yjaZ O Zn-dependent protease
IIPAIDOJ_01321 1.8e-184 appD P Belongs to the ABC transporter superfamily
IIPAIDOJ_01322 4.2e-186 appF E Belongs to the ABC transporter superfamily
IIPAIDOJ_01323 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
IIPAIDOJ_01324 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIPAIDOJ_01325 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIPAIDOJ_01326 5e-147 yjbA S Belongs to the UPF0736 family
IIPAIDOJ_01327 3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IIPAIDOJ_01328 0.0 oppA E ABC transporter substrate-binding protein
IIPAIDOJ_01329 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIPAIDOJ_01330 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIPAIDOJ_01331 2e-197 oppD P Belongs to the ABC transporter superfamily
IIPAIDOJ_01332 7.9e-171 oppF E Belongs to the ABC transporter superfamily
IIPAIDOJ_01333 1.2e-209 yjbB EGP Major Facilitator Superfamily
IIPAIDOJ_01334 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIPAIDOJ_01335 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IIPAIDOJ_01336 2.3e-111 yjbE P Integral membrane protein TerC family
IIPAIDOJ_01337 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IIPAIDOJ_01338 4.9e-218 yjbF S Competence protein
IIPAIDOJ_01339 0.0 pepF E oligoendopeptidase F
IIPAIDOJ_01340 5.2e-20
IIPAIDOJ_01342 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IIPAIDOJ_01343 3.7e-72 yjbI S Bacterial-like globin
IIPAIDOJ_01344 6.1e-89 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IIPAIDOJ_01345 9.2e-101 yjbK S protein conserved in bacteria
IIPAIDOJ_01346 7.1e-62 yjbL S Belongs to the UPF0738 family
IIPAIDOJ_01347 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
IIPAIDOJ_01348 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIPAIDOJ_01349 5.2e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IIPAIDOJ_01350 9.6e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IIPAIDOJ_01351 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IIPAIDOJ_01352 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IIPAIDOJ_01353 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
IIPAIDOJ_01354 5.7e-216 thiO 1.4.3.19 E Glycine oxidase
IIPAIDOJ_01355 1.5e-29 thiS H thiamine diphosphate biosynthetic process
IIPAIDOJ_01356 1.1e-133 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IIPAIDOJ_01357 5.6e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IIPAIDOJ_01358 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IIPAIDOJ_01359 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IIPAIDOJ_01360 5.9e-54 yjbX S Spore coat protein
IIPAIDOJ_01361 5.2e-83 cotZ S Spore coat protein
IIPAIDOJ_01362 3.4e-96 cotY S Spore coat protein Z
IIPAIDOJ_01363 6.4e-77 cotX S Spore Coat Protein X and V domain
IIPAIDOJ_01364 8.5e-32 cotW
IIPAIDOJ_01365 2.3e-55 cotV S Spore Coat Protein X and V domain
IIPAIDOJ_01366 4.3e-56 yjcA S Protein of unknown function (DUF1360)
IIPAIDOJ_01369 2.9e-38 spoVIF S Stage VI sporulation protein F
IIPAIDOJ_01370 0.0 yjcD 3.6.4.12 L DNA helicase
IIPAIDOJ_01371 1.7e-38
IIPAIDOJ_01372 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIPAIDOJ_01373 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
IIPAIDOJ_01374 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
IIPAIDOJ_01375 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IIPAIDOJ_01376 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IIPAIDOJ_01377 5.4e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
IIPAIDOJ_01378 1.2e-211 yjcL S Protein of unknown function (DUF819)
IIPAIDOJ_01380 5.1e-18
IIPAIDOJ_01381 5.4e-27
IIPAIDOJ_01382 2e-30
IIPAIDOJ_01383 1.2e-244 M nucleic acid phosphodiester bond hydrolysis
IIPAIDOJ_01384 3.1e-08
IIPAIDOJ_01387 4.1e-180 S response regulator aspartate phosphatase
IIPAIDOJ_01388 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
IIPAIDOJ_01389 2e-140 IQ Enoyl-(Acyl carrier protein) reductase
IIPAIDOJ_01391 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
IIPAIDOJ_01392 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
IIPAIDOJ_01393 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
IIPAIDOJ_01394 1e-45 yjdF S Protein of unknown function (DUF2992)
IIPAIDOJ_01395 7.6e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
IIPAIDOJ_01397 2.2e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IIPAIDOJ_01398 7.1e-29 S Domain of unknown function (DUF4177)
IIPAIDOJ_01399 1e-51 yjdJ S Domain of unknown function (DUF4306)
IIPAIDOJ_01400 1.2e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IIPAIDOJ_01402 3.2e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
IIPAIDOJ_01403 1.8e-81 S Protein of unknown function (DUF2690)
IIPAIDOJ_01404 8.9e-20 yjfB S Putative motility protein
IIPAIDOJ_01405 3.1e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
IIPAIDOJ_01406 2.7e-45 T PhoQ Sensor
IIPAIDOJ_01407 1.7e-102 yjgB S Domain of unknown function (DUF4309)
IIPAIDOJ_01408 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
IIPAIDOJ_01409 6.3e-94 yjgD S Protein of unknown function (DUF1641)
IIPAIDOJ_01410 2e-10 S Domain of unknown function (DUF4352)
IIPAIDOJ_01411 9.6e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
IIPAIDOJ_01413 6.1e-224 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
IIPAIDOJ_01414 1.2e-216 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IIPAIDOJ_01415 8.2e-30
IIPAIDOJ_01416 1.7e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IIPAIDOJ_01417 9.5e-122 ybbM S transport system, permease component
IIPAIDOJ_01418 4.9e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
IIPAIDOJ_01419 1e-40 yjlA EG Putative multidrug resistance efflux transporter
IIPAIDOJ_01420 5.7e-91 yjlB S Cupin domain
IIPAIDOJ_01421 7.1e-66 yjlC S Protein of unknown function (DUF1641)
IIPAIDOJ_01422 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
IIPAIDOJ_01423 6.1e-279 uxaC 5.3.1.12 G glucuronate isomerase
IIPAIDOJ_01424 7.1e-248 yjmB G symporter YjmB
IIPAIDOJ_01425 2.7e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IIPAIDOJ_01426 7.2e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
IIPAIDOJ_01427 8.9e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
IIPAIDOJ_01428 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPAIDOJ_01429 4.1e-226 exuT G Sugar (and other) transporter
IIPAIDOJ_01430 1.5e-183 exuR K transcriptional
IIPAIDOJ_01431 9.9e-285 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
IIPAIDOJ_01432 1.2e-282 uxaA 4.2.1.7, 4.4.1.24 G Altronate
IIPAIDOJ_01433 7.4e-130 MA20_18170 S membrane transporter protein
IIPAIDOJ_01434 2.3e-78 yjoA S DinB family
IIPAIDOJ_01435 1.4e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
IIPAIDOJ_01436 1e-212 S response regulator aspartate phosphatase
IIPAIDOJ_01438 2.4e-40 S YCII-related domain
IIPAIDOJ_01439 8e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
IIPAIDOJ_01440 5.2e-60 yjqA S Bacterial PH domain
IIPAIDOJ_01441 2.1e-111 yjqB S Pfam:DUF867
IIPAIDOJ_01442 4.4e-160 ydbD P Catalase
IIPAIDOJ_01443 2.3e-110 xkdA E IrrE N-terminal-like domain
IIPAIDOJ_01444 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
IIPAIDOJ_01446 5.9e-157 xkdB K sequence-specific DNA binding
IIPAIDOJ_01447 9.2e-118 xkdC L Bacterial dnaA protein
IIPAIDOJ_01450 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
IIPAIDOJ_01451 3.8e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IIPAIDOJ_01452 5.3e-139 xtmA L phage terminase small subunit
IIPAIDOJ_01453 3.4e-252 xtmB S phage terminase, large subunit
IIPAIDOJ_01454 2.3e-284 yqbA S portal protein
IIPAIDOJ_01455 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
IIPAIDOJ_01456 1.7e-168 xkdG S Phage capsid family
IIPAIDOJ_01457 3.7e-61 yqbG S Protein of unknown function (DUF3199)
IIPAIDOJ_01458 5.6e-64 yqbH S Domain of unknown function (DUF3599)
IIPAIDOJ_01459 4.9e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
IIPAIDOJ_01460 1.9e-77 xkdJ
IIPAIDOJ_01461 2.5e-256 xkdK S Phage tail sheath C-terminal domain
IIPAIDOJ_01462 6.1e-76 xkdM S Phage tail tube protein
IIPAIDOJ_01463 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
IIPAIDOJ_01464 1.7e-267 xkdO L Transglycosylase SLT domain
IIPAIDOJ_01465 2.7e-118 xkdP S Lysin motif
IIPAIDOJ_01466 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
IIPAIDOJ_01467 2.1e-39 xkdR S Protein of unknown function (DUF2577)
IIPAIDOJ_01468 1.1e-69 xkdS S Protein of unknown function (DUF2634)
IIPAIDOJ_01469 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IIPAIDOJ_01470 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
IIPAIDOJ_01471 1.9e-40
IIPAIDOJ_01472 1e-177
IIPAIDOJ_01473 1.6e-44 xkdW S XkdW protein
IIPAIDOJ_01474 5.5e-22 xkdX
IIPAIDOJ_01475 2.8e-154 xepA
IIPAIDOJ_01476 2.8e-39 xhlA S Haemolysin XhlA
IIPAIDOJ_01477 9.3e-40 xhlB S SPP1 phage holin
IIPAIDOJ_01478 3.5e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IIPAIDOJ_01479 6.7e-23 spoIISB S Stage II sporulation protein SB
IIPAIDOJ_01480 5.2e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
IIPAIDOJ_01481 5.8e-175 pit P phosphate transporter
IIPAIDOJ_01482 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
IIPAIDOJ_01483 4.7e-233 steT E amino acid
IIPAIDOJ_01484 6.7e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
IIPAIDOJ_01486 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIPAIDOJ_01487 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IIPAIDOJ_01488 6.8e-211 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IIPAIDOJ_01489 2.1e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
IIPAIDOJ_01490 5.1e-153 dppA E D-aminopeptidase
IIPAIDOJ_01491 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIPAIDOJ_01492 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIPAIDOJ_01493 7.8e-188 dppD P Belongs to the ABC transporter superfamily
IIPAIDOJ_01494 0.0 dppE E ABC transporter substrate-binding protein
IIPAIDOJ_01496 9.9e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IIPAIDOJ_01497 4.8e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IIPAIDOJ_01498 1.5e-169 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IIPAIDOJ_01499 8.5e-187 ykfD E Belongs to the ABC transporter superfamily
IIPAIDOJ_01500 1.2e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
IIPAIDOJ_01501 2.2e-159 ykgA E Amidinotransferase
IIPAIDOJ_01502 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
IIPAIDOJ_01503 4e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IIPAIDOJ_01504 5e-10
IIPAIDOJ_01505 1.5e-127 ykjA S Protein of unknown function (DUF421)
IIPAIDOJ_01506 2e-97 ykkA S Protein of unknown function (DUF664)
IIPAIDOJ_01507 3.6e-96 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IIPAIDOJ_01508 1.7e-54 ykkC P Multidrug resistance protein
IIPAIDOJ_01509 9.1e-50 ykkD P Multidrug resistance protein
IIPAIDOJ_01510 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IIPAIDOJ_01511 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IIPAIDOJ_01512 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IIPAIDOJ_01513 4.8e-70 ohrA O Organic hydroperoxide resistance protein
IIPAIDOJ_01514 3.9e-75 ohrR K COG1846 Transcriptional regulators
IIPAIDOJ_01515 8.4e-72 ohrB O Organic hydroperoxide resistance protein
IIPAIDOJ_01516 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
IIPAIDOJ_01517 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IIPAIDOJ_01518 5e-176 isp O Belongs to the peptidase S8 family
IIPAIDOJ_01519 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IIPAIDOJ_01520 5.8e-135 ykoC P Cobalt transport protein
IIPAIDOJ_01521 1.3e-304 P ABC transporter, ATP-binding protein
IIPAIDOJ_01522 1e-97 ykoE S ABC-type cobalt transport system, permease component
IIPAIDOJ_01523 1.4e-107 ykoF S YKOF-related Family
IIPAIDOJ_01524 7.1e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_01525 1.2e-239 ykoH 2.7.13.3 T Histidine kinase
IIPAIDOJ_01526 2.1e-112 ykoI S Peptidase propeptide and YPEB domain
IIPAIDOJ_01527 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
IIPAIDOJ_01530 2.2e-222 mgtE P Acts as a magnesium transporter
IIPAIDOJ_01531 1.4e-53 tnrA K transcriptional
IIPAIDOJ_01532 1.3e-17
IIPAIDOJ_01533 3.4e-25 ykoL
IIPAIDOJ_01534 1.3e-81 mhqR K transcriptional
IIPAIDOJ_01535 2.4e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IIPAIDOJ_01536 2.7e-97 ykoP G polysaccharide deacetylase
IIPAIDOJ_01537 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
IIPAIDOJ_01538 0.0 ykoS
IIPAIDOJ_01539 6.2e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IIPAIDOJ_01540 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
IIPAIDOJ_01541 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IIPAIDOJ_01542 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
IIPAIDOJ_01543 1.6e-106 ykoX S membrane-associated protein
IIPAIDOJ_01544 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IIPAIDOJ_01545 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIPAIDOJ_01546 3.1e-108 rsgI S Anti-sigma factor N-terminus
IIPAIDOJ_01547 1.9e-26 sspD S small acid-soluble spore protein
IIPAIDOJ_01548 5.6e-124 ykrK S Domain of unknown function (DUF1836)
IIPAIDOJ_01549 3.5e-155 htpX O Belongs to the peptidase M48B family
IIPAIDOJ_01550 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
IIPAIDOJ_01551 1.2e-10 ydfR S Protein of unknown function (DUF421)
IIPAIDOJ_01552 4.1e-18 ykzE
IIPAIDOJ_01553 2.7e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
IIPAIDOJ_01554 0.0 kinE 2.7.13.3 T Histidine kinase
IIPAIDOJ_01555 1.2e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IIPAIDOJ_01557 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IIPAIDOJ_01558 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IIPAIDOJ_01559 8.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IIPAIDOJ_01560 3.1e-231 mtnE 2.6.1.83 E Aminotransferase
IIPAIDOJ_01561 6.5e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IIPAIDOJ_01562 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IIPAIDOJ_01563 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IIPAIDOJ_01564 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IIPAIDOJ_01565 2.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
IIPAIDOJ_01566 7.5e-10 S Spo0E like sporulation regulatory protein
IIPAIDOJ_01567 4.9e-62 eag
IIPAIDOJ_01568 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
IIPAIDOJ_01569 1.3e-75 ykvE K transcriptional
IIPAIDOJ_01570 2.5e-125 motB N Flagellar motor protein
IIPAIDOJ_01571 1e-137 motA N flagellar motor
IIPAIDOJ_01572 0.0 clpE O Belongs to the ClpA ClpB family
IIPAIDOJ_01573 3.3e-181 ykvI S membrane
IIPAIDOJ_01574 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IIPAIDOJ_01575 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
IIPAIDOJ_01576 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IIPAIDOJ_01577 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IIPAIDOJ_01578 2.2e-60 ykvN K HxlR-like helix-turn-helix
IIPAIDOJ_01579 7e-133 IQ Enoyl-(Acyl carrier protein) reductase
IIPAIDOJ_01580 1.5e-230 ykvP 3.5.1.28 M Glycosyl transferases group 1
IIPAIDOJ_01581 3.5e-35 3.5.1.104 M LysM domain
IIPAIDOJ_01582 2.4e-162 G Glycosyl hydrolases family 18
IIPAIDOJ_01583 2.1e-45 ykvR S Protein of unknown function (DUF3219)
IIPAIDOJ_01584 6e-25 ykvS S protein conserved in bacteria
IIPAIDOJ_01585 1e-27
IIPAIDOJ_01586 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
IIPAIDOJ_01587 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIPAIDOJ_01588 9.2e-89 stoA CO thiol-disulfide
IIPAIDOJ_01589 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IIPAIDOJ_01590 7.4e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IIPAIDOJ_01591 8.3e-179 ykvZ 5.1.1.1 K Transcriptional regulator
IIPAIDOJ_01592 7.6e-128 glcT K antiterminator
IIPAIDOJ_01593 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IIPAIDOJ_01594 2.1e-39 ptsH G phosphocarrier protein HPr
IIPAIDOJ_01595 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIPAIDOJ_01596 7.2e-39 splA S Transcriptional regulator
IIPAIDOJ_01597 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
IIPAIDOJ_01598 5.4e-127 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIPAIDOJ_01599 3.5e-256 mcpC NT chemotaxis protein
IIPAIDOJ_01600 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IIPAIDOJ_01601 1.8e-123 ykwD J protein with SCP PR1 domains
IIPAIDOJ_01602 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
IIPAIDOJ_01603 0.0 pilS 2.7.13.3 T Histidine kinase
IIPAIDOJ_01604 6.3e-221 patA 2.6.1.1 E Aminotransferase
IIPAIDOJ_01605 3.7e-15
IIPAIDOJ_01606 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
IIPAIDOJ_01607 4.9e-84 ykyB S YkyB-like protein
IIPAIDOJ_01608 2.8e-238 ykuC EGP Major facilitator Superfamily
IIPAIDOJ_01609 1.8e-87 ykuD S protein conserved in bacteria
IIPAIDOJ_01610 9.4e-166 ykuE S Metallophosphoesterase
IIPAIDOJ_01611 1.4e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIPAIDOJ_01612 5.2e-234 ykuI T Diguanylate phosphodiesterase
IIPAIDOJ_01613 3.9e-37 ykuJ S protein conserved in bacteria
IIPAIDOJ_01614 4.4e-94 ykuK S Ribonuclease H-like
IIPAIDOJ_01615 3.9e-27 ykzF S Antirepressor AbbA
IIPAIDOJ_01616 1.6e-76 ykuL S CBS domain
IIPAIDOJ_01617 3.5e-168 ccpC K Transcriptional regulator
IIPAIDOJ_01618 6.5e-84 fld C Flavodoxin domain
IIPAIDOJ_01619 2.6e-174 ykuO
IIPAIDOJ_01620 3.9e-78 fld C Flavodoxin
IIPAIDOJ_01621 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IIPAIDOJ_01622 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IIPAIDOJ_01623 9e-37 ykuS S Belongs to the UPF0180 family
IIPAIDOJ_01624 8.8e-142 ykuT M Mechanosensitive ion channel
IIPAIDOJ_01625 3.9e-101 ykuU O Alkyl hydroperoxide reductase
IIPAIDOJ_01626 4.5e-79 ykuV CO thiol-disulfide
IIPAIDOJ_01627 5.8e-95 rok K Repressor of ComK
IIPAIDOJ_01628 4.2e-146 yknT
IIPAIDOJ_01629 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IIPAIDOJ_01630 1.3e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IIPAIDOJ_01631 7.6e-244 moeA 2.10.1.1 H molybdopterin
IIPAIDOJ_01632 9.3e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IIPAIDOJ_01633 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
IIPAIDOJ_01634 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IIPAIDOJ_01635 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
IIPAIDOJ_01636 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
IIPAIDOJ_01637 3.6e-115 yknW S Yip1 domain
IIPAIDOJ_01638 4.7e-157 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IIPAIDOJ_01639 1e-122 macB V ABC transporter, ATP-binding protein
IIPAIDOJ_01640 1.6e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
IIPAIDOJ_01641 3.1e-136 fruR K Transcriptional regulator
IIPAIDOJ_01642 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
IIPAIDOJ_01643 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IIPAIDOJ_01644 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IIPAIDOJ_01645 8.1e-39 ykoA
IIPAIDOJ_01646 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IIPAIDOJ_01647 2.5e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIPAIDOJ_01648 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IIPAIDOJ_01649 1.1e-12 S Uncharacterized protein YkpC
IIPAIDOJ_01650 1.7e-182 mreB D Rod-share determining protein MreBH
IIPAIDOJ_01651 1.5e-43 abrB K of stationary sporulation gene expression
IIPAIDOJ_01652 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
IIPAIDOJ_01653 8.3e-159 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
IIPAIDOJ_01654 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
IIPAIDOJ_01655 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IIPAIDOJ_01656 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIPAIDOJ_01657 1.4e-30 ykzG S Belongs to the UPF0356 family
IIPAIDOJ_01658 5.5e-147 ykrA S hydrolases of the HAD superfamily
IIPAIDOJ_01659 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIPAIDOJ_01661 2e-115 recN L Putative cell-wall binding lipoprotein
IIPAIDOJ_01662 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IIPAIDOJ_01663 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IIPAIDOJ_01664 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIPAIDOJ_01665 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IIPAIDOJ_01666 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
IIPAIDOJ_01667 3.5e-277 speA 4.1.1.19 E Arginine
IIPAIDOJ_01668 5.9e-42 yktA S Belongs to the UPF0223 family
IIPAIDOJ_01669 2.1e-117 yktB S Belongs to the UPF0637 family
IIPAIDOJ_01670 7.1e-26 ykzI
IIPAIDOJ_01671 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
IIPAIDOJ_01672 2e-77 ykzC S Acetyltransferase (GNAT) family
IIPAIDOJ_01673 2.7e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IIPAIDOJ_01674 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
IIPAIDOJ_01675 0.0 ylaA
IIPAIDOJ_01676 2.7e-42 ylaB
IIPAIDOJ_01677 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
IIPAIDOJ_01678 9.1e-12 sigC S Putative zinc-finger
IIPAIDOJ_01679 7.7e-37 ylaE
IIPAIDOJ_01680 8.2e-22 S Family of unknown function (DUF5325)
IIPAIDOJ_01681 0.0 typA T GTP-binding protein TypA
IIPAIDOJ_01682 5.6e-47 ylaH S YlaH-like protein
IIPAIDOJ_01683 2.5e-32 ylaI S protein conserved in bacteria
IIPAIDOJ_01684 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IIPAIDOJ_01685 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
IIPAIDOJ_01686 8.7e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IIPAIDOJ_01687 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
IIPAIDOJ_01688 8.7e-44 ylaN S Belongs to the UPF0358 family
IIPAIDOJ_01689 9.4e-212 ftsW D Belongs to the SEDS family
IIPAIDOJ_01690 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IIPAIDOJ_01691 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IIPAIDOJ_01692 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IIPAIDOJ_01693 5.2e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IIPAIDOJ_01694 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IIPAIDOJ_01695 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IIPAIDOJ_01696 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IIPAIDOJ_01697 4.4e-166 ctaG S cytochrome c oxidase
IIPAIDOJ_01698 7e-62 ylbA S YugN-like family
IIPAIDOJ_01699 2.6e-74 ylbB T COG0517 FOG CBS domain
IIPAIDOJ_01700 9.6e-200 ylbC S protein with SCP PR1 domains
IIPAIDOJ_01701 3.4e-62 ylbD S Putative coat protein
IIPAIDOJ_01702 1.5e-36 ylbE S YlbE-like protein
IIPAIDOJ_01703 1.8e-75 ylbF S Belongs to the UPF0342 family
IIPAIDOJ_01704 7.5e-39 ylbG S UPF0298 protein
IIPAIDOJ_01705 1e-96 rsmD 2.1.1.171 L Methyltransferase
IIPAIDOJ_01706 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IIPAIDOJ_01707 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
IIPAIDOJ_01708 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
IIPAIDOJ_01709 5.7e-186 ylbL T Belongs to the peptidase S16 family
IIPAIDOJ_01710 6.6e-229 ylbM S Belongs to the UPF0348 family
IIPAIDOJ_01712 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
IIPAIDOJ_01713 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IIPAIDOJ_01714 2.2e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IIPAIDOJ_01715 1.5e-88 ylbP K n-acetyltransferase
IIPAIDOJ_01716 8.9e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIPAIDOJ_01717 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IIPAIDOJ_01718 2.9e-78 mraZ K Belongs to the MraZ family
IIPAIDOJ_01719 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IIPAIDOJ_01720 3.7e-44 ftsL D Essential cell division protein
IIPAIDOJ_01721 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IIPAIDOJ_01722 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
IIPAIDOJ_01723 1.2e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IIPAIDOJ_01724 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IIPAIDOJ_01725 2.2e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IIPAIDOJ_01726 5.7e-186 spoVE D Belongs to the SEDS family
IIPAIDOJ_01727 4.8e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IIPAIDOJ_01728 5.3e-167 murB 1.3.1.98 M cell wall formation
IIPAIDOJ_01729 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IIPAIDOJ_01730 4.1e-103 ylxW S protein conserved in bacteria
IIPAIDOJ_01731 8.2e-117 ylxX S protein conserved in bacteria
IIPAIDOJ_01732 6.2e-58 sbp S small basic protein
IIPAIDOJ_01733 1.6e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IIPAIDOJ_01734 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IIPAIDOJ_01735 0.0 bpr O COG1404 Subtilisin-like serine proteases
IIPAIDOJ_01737 6.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IIPAIDOJ_01738 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIPAIDOJ_01739 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIPAIDOJ_01740 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IIPAIDOJ_01741 4.1e-250 argE 3.5.1.16 E Acetylornithine deacetylase
IIPAIDOJ_01742 2.4e-37 ylmC S sporulation protein
IIPAIDOJ_01743 2.4e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
IIPAIDOJ_01744 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IIPAIDOJ_01745 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IIPAIDOJ_01746 1.6e-39 yggT S membrane
IIPAIDOJ_01747 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
IIPAIDOJ_01748 2.6e-67 divIVA D Cell division initiation protein
IIPAIDOJ_01749 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IIPAIDOJ_01750 3.8e-63 dksA T COG1734 DnaK suppressor protein
IIPAIDOJ_01751 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IIPAIDOJ_01752 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IIPAIDOJ_01753 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IIPAIDOJ_01754 5.8e-231 pyrP F Xanthine uracil
IIPAIDOJ_01755 5.9e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IIPAIDOJ_01756 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IIPAIDOJ_01757 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IIPAIDOJ_01758 0.0 carB 6.3.5.5 F Belongs to the CarB family
IIPAIDOJ_01759 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IIPAIDOJ_01760 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IIPAIDOJ_01761 4.1e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IIPAIDOJ_01762 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IIPAIDOJ_01763 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
IIPAIDOJ_01764 5.4e-179 cysP P phosphate transporter
IIPAIDOJ_01765 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
IIPAIDOJ_01766 6.2e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
IIPAIDOJ_01767 2e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IIPAIDOJ_01768 1.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
IIPAIDOJ_01769 1.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
IIPAIDOJ_01770 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IIPAIDOJ_01771 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
IIPAIDOJ_01772 2.4e-156 yloC S stress-induced protein
IIPAIDOJ_01773 1.5e-40 ylzA S Belongs to the UPF0296 family
IIPAIDOJ_01774 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IIPAIDOJ_01775 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IIPAIDOJ_01776 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IIPAIDOJ_01777 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIPAIDOJ_01778 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIPAIDOJ_01779 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IIPAIDOJ_01780 1.2e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IIPAIDOJ_01781 3.4e-205 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IIPAIDOJ_01782 4.6e-140 stp 3.1.3.16 T phosphatase
IIPAIDOJ_01783 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IIPAIDOJ_01784 5.6e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IIPAIDOJ_01785 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IIPAIDOJ_01786 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
IIPAIDOJ_01787 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IIPAIDOJ_01788 5.5e-59 asp S protein conserved in bacteria
IIPAIDOJ_01789 1.6e-299 yloV S kinase related to dihydroxyacetone kinase
IIPAIDOJ_01790 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
IIPAIDOJ_01791 1.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
IIPAIDOJ_01792 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IIPAIDOJ_01793 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IIPAIDOJ_01794 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IIPAIDOJ_01795 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IIPAIDOJ_01796 5.1e-128 IQ reductase
IIPAIDOJ_01797 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIPAIDOJ_01798 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IIPAIDOJ_01799 0.0 smc D Required for chromosome condensation and partitioning
IIPAIDOJ_01800 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IIPAIDOJ_01801 2.9e-87
IIPAIDOJ_01802 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IIPAIDOJ_01803 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IIPAIDOJ_01804 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IIPAIDOJ_01805 4.5e-36 ylqC S Belongs to the UPF0109 family
IIPAIDOJ_01806 1.4e-60 ylqD S YlqD protein
IIPAIDOJ_01807 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IIPAIDOJ_01808 6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IIPAIDOJ_01809 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IIPAIDOJ_01810 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IIPAIDOJ_01811 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIPAIDOJ_01812 1.1e-285 ylqG
IIPAIDOJ_01813 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
IIPAIDOJ_01814 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IIPAIDOJ_01815 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IIPAIDOJ_01816 4e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
IIPAIDOJ_01817 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIPAIDOJ_01818 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IIPAIDOJ_01819 5.7e-169 xerC L tyrosine recombinase XerC
IIPAIDOJ_01820 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IIPAIDOJ_01821 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IIPAIDOJ_01822 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IIPAIDOJ_01823 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IIPAIDOJ_01824 9.9e-74 flgC N Belongs to the flagella basal body rod proteins family
IIPAIDOJ_01825 1.9e-31 fliE N Flagellar hook-basal body
IIPAIDOJ_01826 6.3e-248 fliF N The M ring may be actively involved in energy transduction
IIPAIDOJ_01827 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IIPAIDOJ_01828 4.8e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
IIPAIDOJ_01829 9.4e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IIPAIDOJ_01830 1.5e-69 fliJ N Flagellar biosynthesis chaperone
IIPAIDOJ_01831 2.2e-36 ylxF S MgtE intracellular N domain
IIPAIDOJ_01832 7.1e-214 fliK N Flagellar hook-length control protein
IIPAIDOJ_01833 2.3e-72 flgD N Flagellar basal body rod modification protein
IIPAIDOJ_01834 1.9e-136 flgG N Flagellar basal body rod
IIPAIDOJ_01835 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
IIPAIDOJ_01836 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IIPAIDOJ_01837 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IIPAIDOJ_01838 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
IIPAIDOJ_01839 5.1e-95 fliZ N Flagellar biosynthesis protein, FliO
IIPAIDOJ_01840 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
IIPAIDOJ_01841 3.7e-36 fliQ N Role in flagellar biosynthesis
IIPAIDOJ_01842 3.6e-132 fliR N Flagellar biosynthetic protein FliR
IIPAIDOJ_01843 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IIPAIDOJ_01844 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IIPAIDOJ_01845 7.5e-200 flhF N Flagellar biosynthesis regulator FlhF
IIPAIDOJ_01846 1.7e-157 flhG D Belongs to the ParA family
IIPAIDOJ_01847 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IIPAIDOJ_01848 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
IIPAIDOJ_01849 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
IIPAIDOJ_01850 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IIPAIDOJ_01851 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IIPAIDOJ_01852 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIPAIDOJ_01853 3.1e-76 ylxL
IIPAIDOJ_01854 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
IIPAIDOJ_01855 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IIPAIDOJ_01856 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IIPAIDOJ_01857 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IIPAIDOJ_01858 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IIPAIDOJ_01859 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
IIPAIDOJ_01860 1.7e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IIPAIDOJ_01861 1.7e-232 rasP M zinc metalloprotease
IIPAIDOJ_01862 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IIPAIDOJ_01863 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIPAIDOJ_01864 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
IIPAIDOJ_01865 1.1e-203 nusA K Participates in both transcription termination and antitermination
IIPAIDOJ_01866 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
IIPAIDOJ_01867 3.1e-47 ylxQ J ribosomal protein
IIPAIDOJ_01868 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IIPAIDOJ_01869 3.9e-44 ylxP S protein conserved in bacteria
IIPAIDOJ_01870 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IIPAIDOJ_01871 5.6e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IIPAIDOJ_01872 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IIPAIDOJ_01873 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IIPAIDOJ_01874 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IIPAIDOJ_01875 2.8e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
IIPAIDOJ_01876 4.4e-233 pepR S Belongs to the peptidase M16 family
IIPAIDOJ_01877 2.6e-42 ymxH S YlmC YmxH family
IIPAIDOJ_01878 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
IIPAIDOJ_01879 4.8e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IIPAIDOJ_01880 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IIPAIDOJ_01881 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IIPAIDOJ_01882 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IIPAIDOJ_01883 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIPAIDOJ_01884 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
IIPAIDOJ_01885 4.4e-32 S YlzJ-like protein
IIPAIDOJ_01886 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IIPAIDOJ_01887 1.4e-133 ymfC K Transcriptional regulator
IIPAIDOJ_01888 5.6e-128 ymfD EGP Major facilitator Superfamily
IIPAIDOJ_01889 1.8e-60 ymfD EGP Major facilitator Superfamily
IIPAIDOJ_01890 3.5e-233 ymfF S Peptidase M16
IIPAIDOJ_01891 5.1e-240 ymfH S zinc protease
IIPAIDOJ_01892 2.7e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IIPAIDOJ_01893 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
IIPAIDOJ_01894 2.7e-143 ymfK S Protein of unknown function (DUF3388)
IIPAIDOJ_01895 1.9e-124 ymfM S protein conserved in bacteria
IIPAIDOJ_01896 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIPAIDOJ_01897 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
IIPAIDOJ_01898 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IIPAIDOJ_01899 8.8e-215 pbpX V Beta-lactamase
IIPAIDOJ_01900 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
IIPAIDOJ_01901 7.1e-152 ymdB S protein conserved in bacteria
IIPAIDOJ_01902 1.2e-36 spoVS S Stage V sporulation protein S
IIPAIDOJ_01903 1.5e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IIPAIDOJ_01904 2.7e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IIPAIDOJ_01905 5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IIPAIDOJ_01906 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IIPAIDOJ_01907 2.2e-88 cotE S Spore coat protein
IIPAIDOJ_01908 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IIPAIDOJ_01909 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IIPAIDOJ_01910 2.6e-69 S Regulatory protein YrvL
IIPAIDOJ_01911 3e-96 ymcC S Membrane
IIPAIDOJ_01912 4.4e-109 pksA K Transcriptional regulator
IIPAIDOJ_01913 7.2e-129 pksB 3.1.2.6 S Polyketide biosynthesis
IIPAIDOJ_01914 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IIPAIDOJ_01916 2.3e-184 pksD Q Acyl transferase domain
IIPAIDOJ_01917 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IIPAIDOJ_01918 1.4e-37 acpK IQ Phosphopantetheine attachment site
IIPAIDOJ_01919 1.6e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIPAIDOJ_01920 5.1e-245 pksG 2.3.3.10 I synthase
IIPAIDOJ_01921 5.5e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
IIPAIDOJ_01922 1.5e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IIPAIDOJ_01923 0.0 rhiB IQ polyketide synthase
IIPAIDOJ_01924 0.0 pfaA Q Polyketide synthase of type I
IIPAIDOJ_01925 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
IIPAIDOJ_01926 0.0 dhbF IQ polyketide synthase
IIPAIDOJ_01927 0.0 pks13 HQ Beta-ketoacyl synthase
IIPAIDOJ_01928 2.8e-232 cypA C Cytochrome P450
IIPAIDOJ_01929 7.6e-61 ymzB
IIPAIDOJ_01930 1.2e-160 ymaE S Metallo-beta-lactamase superfamily
IIPAIDOJ_01931 3.9e-251 aprX O Belongs to the peptidase S8 family
IIPAIDOJ_01932 1.9e-07 K Transcriptional regulator
IIPAIDOJ_01933 2.1e-126 ymaC S Replication protein
IIPAIDOJ_01934 5.1e-78 ymaD O redox protein, regulator of disulfide bond formation
IIPAIDOJ_01935 4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
IIPAIDOJ_01936 1.6e-49 ebrA P Small Multidrug Resistance protein
IIPAIDOJ_01938 2.1e-46 ymaF S YmaF family
IIPAIDOJ_01939 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IIPAIDOJ_01940 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IIPAIDOJ_01941 8.2e-23
IIPAIDOJ_01942 4.5e-22 ymzA
IIPAIDOJ_01943 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
IIPAIDOJ_01944 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIPAIDOJ_01945 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIPAIDOJ_01946 2e-109 ymaB
IIPAIDOJ_01947 2.3e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IIPAIDOJ_01948 1.7e-176 spoVK O stage V sporulation protein K
IIPAIDOJ_01949 7.9e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IIPAIDOJ_01950 3.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IIPAIDOJ_01951 1.1e-68 glnR K transcriptional
IIPAIDOJ_01952 7e-261 glnA 6.3.1.2 E glutamine synthetase
IIPAIDOJ_01953 1.1e-64
IIPAIDOJ_01954 1.5e-15
IIPAIDOJ_01956 7.5e-59
IIPAIDOJ_01957 3e-08 KLT serine threonine protein kinase
IIPAIDOJ_01960 2.8e-72 L phage terminase small subunit
IIPAIDOJ_01961 4.2e-17 S Terminase
IIPAIDOJ_01964 4.5e-12
IIPAIDOJ_01965 3.8e-10
IIPAIDOJ_01966 3.2e-32
IIPAIDOJ_01967 2.1e-36
IIPAIDOJ_01968 1.7e-93 G SMI1-KNR4 cell-wall
IIPAIDOJ_01969 5.3e-133 ynaC
IIPAIDOJ_01970 2.5e-97 ynaD J Acetyltransferase (GNAT) domain
IIPAIDOJ_01971 3.1e-121 ynaE S Domain of unknown function (DUF3885)
IIPAIDOJ_01974 2.3e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
IIPAIDOJ_01975 1.9e-253 xynT G MFS/sugar transport protein
IIPAIDOJ_01976 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
IIPAIDOJ_01977 1.5e-214 xylR GK ROK family
IIPAIDOJ_01978 1.6e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
IIPAIDOJ_01979 1.5e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
IIPAIDOJ_01980 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
IIPAIDOJ_01981 4.7e-255 iolT EGP Major facilitator Superfamily
IIPAIDOJ_01982 1e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIPAIDOJ_01983 5e-81 yncE S Protein of unknown function (DUF2691)
IIPAIDOJ_01984 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
IIPAIDOJ_01985 5.2e-15
IIPAIDOJ_01988 1.5e-163 S Thymidylate synthase
IIPAIDOJ_01990 1.2e-127 S Domain of unknown function, YrpD
IIPAIDOJ_01993 7.9e-25 tatA U protein secretion
IIPAIDOJ_01994 1.8e-71
IIPAIDOJ_01995 1.5e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
IIPAIDOJ_01998 1.2e-283 gerAA EG Spore germination protein
IIPAIDOJ_01999 1.2e-194 gerAB U Spore germination
IIPAIDOJ_02000 1.4e-215 gerLC S Spore germination protein
IIPAIDOJ_02001 5.7e-149 yndG S DoxX-like family
IIPAIDOJ_02002 7.1e-115 yndH S Domain of unknown function (DUF4166)
IIPAIDOJ_02003 3e-306 yndJ S YndJ-like protein
IIPAIDOJ_02005 3.6e-137 yndL S Replication protein
IIPAIDOJ_02006 5.8e-74 yndM S Protein of unknown function (DUF2512)
IIPAIDOJ_02007 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IIPAIDOJ_02008 9.9e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IIPAIDOJ_02009 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IIPAIDOJ_02010 2.1e-109 yneB L resolvase
IIPAIDOJ_02011 4.8e-32 ynzC S UPF0291 protein
IIPAIDOJ_02012 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IIPAIDOJ_02013 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
IIPAIDOJ_02014 1.8e-28 yneF S UPF0154 protein
IIPAIDOJ_02015 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
IIPAIDOJ_02016 7.8e-126 ccdA O cytochrome c biogenesis protein
IIPAIDOJ_02017 3.6e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
IIPAIDOJ_02018 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
IIPAIDOJ_02019 4.2e-74 yneK S Protein of unknown function (DUF2621)
IIPAIDOJ_02020 5.9e-64 hspX O Spore coat protein
IIPAIDOJ_02021 3.9e-19 sspP S Belongs to the SspP family
IIPAIDOJ_02022 2.2e-14 sspO S Belongs to the SspO family
IIPAIDOJ_02023 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IIPAIDOJ_02024 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IIPAIDOJ_02026 1.5e-07 sspN S Small acid-soluble spore protein N family
IIPAIDOJ_02027 8.6e-35 tlp S Belongs to the Tlp family
IIPAIDOJ_02028 1.2e-73 yneP S Thioesterase-like superfamily
IIPAIDOJ_02029 2.9e-53 yneQ
IIPAIDOJ_02030 4.1e-49 yneR S Belongs to the HesB IscA family
IIPAIDOJ_02031 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IIPAIDOJ_02032 6.6e-69 yccU S CoA-binding protein
IIPAIDOJ_02033 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIPAIDOJ_02034 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIPAIDOJ_02035 2.3e-12
IIPAIDOJ_02036 1.3e-57 ynfC
IIPAIDOJ_02037 1.2e-250 agcS E Sodium alanine symporter
IIPAIDOJ_02038 1.3e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
IIPAIDOJ_02040 4.7e-246 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
IIPAIDOJ_02041 1.3e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
IIPAIDOJ_02042 1.6e-79 yngA S membrane
IIPAIDOJ_02043 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IIPAIDOJ_02044 5.5e-104 yngC S membrane-associated protein
IIPAIDOJ_02045 1.1e-231 nrnB S phosphohydrolase (DHH superfamily)
IIPAIDOJ_02046 5.9e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IIPAIDOJ_02047 1.3e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IIPAIDOJ_02048 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
IIPAIDOJ_02049 6.6e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
IIPAIDOJ_02050 1.6e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
IIPAIDOJ_02051 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IIPAIDOJ_02052 9.8e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
IIPAIDOJ_02053 9e-26 S Family of unknown function (DUF5367)
IIPAIDOJ_02055 7.7e-304 yngK T Glycosyl hydrolase-like 10
IIPAIDOJ_02056 2.8e-64 yngL S Protein of unknown function (DUF1360)
IIPAIDOJ_02057 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
IIPAIDOJ_02058 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPAIDOJ_02059 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPAIDOJ_02062 2e-08
IIPAIDOJ_02069 1.3e-09
IIPAIDOJ_02070 7.8e-08
IIPAIDOJ_02079 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IIPAIDOJ_02080 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IIPAIDOJ_02081 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
IIPAIDOJ_02082 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
IIPAIDOJ_02083 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IIPAIDOJ_02084 8.4e-76 tspO T membrane
IIPAIDOJ_02085 2.8e-204 cotI S Spore coat protein
IIPAIDOJ_02086 1.8e-217 cotSA M Glycosyl transferases group 1
IIPAIDOJ_02087 4.3e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
IIPAIDOJ_02089 3.3e-233 ytcC M Glycosyltransferase Family 4
IIPAIDOJ_02090 1.7e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
IIPAIDOJ_02091 9.8e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IIPAIDOJ_02092 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
IIPAIDOJ_02093 2.6e-132 dksA T COG1734 DnaK suppressor protein
IIPAIDOJ_02094 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
IIPAIDOJ_02095 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IIPAIDOJ_02096 1.4e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IIPAIDOJ_02097 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IIPAIDOJ_02098 4.8e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IIPAIDOJ_02099 2.7e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IIPAIDOJ_02100 7.4e-169 troA P Belongs to the bacterial solute-binding protein 9 family
IIPAIDOJ_02101 3.6e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IIPAIDOJ_02102 6.7e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IIPAIDOJ_02103 4.4e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IIPAIDOJ_02104 1.1e-24 S Domain of Unknown Function (DUF1540)
IIPAIDOJ_02105 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IIPAIDOJ_02106 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
IIPAIDOJ_02107 6.1e-41 rpmE2 J Ribosomal protein L31
IIPAIDOJ_02108 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IIPAIDOJ_02109 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IIPAIDOJ_02110 9.9e-71 ytkA S YtkA-like
IIPAIDOJ_02112 2.1e-76 dps P Belongs to the Dps family
IIPAIDOJ_02113 7.8e-62 ytkC S Bacteriophage holin family
IIPAIDOJ_02114 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
IIPAIDOJ_02115 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IIPAIDOJ_02116 1.4e-144 ytlC P ABC transporter
IIPAIDOJ_02117 2.3e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IIPAIDOJ_02118 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IIPAIDOJ_02119 1.2e-38 ytmB S Protein of unknown function (DUF2584)
IIPAIDOJ_02120 3.3e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IIPAIDOJ_02121 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IIPAIDOJ_02122 0.0 asnB 6.3.5.4 E Asparagine synthase
IIPAIDOJ_02123 1.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
IIPAIDOJ_02124 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IIPAIDOJ_02125 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
IIPAIDOJ_02126 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
IIPAIDOJ_02127 9.7e-106 ytqB J Putative rRNA methylase
IIPAIDOJ_02128 1.8e-189 yhcC S Fe-S oxidoreductase
IIPAIDOJ_02129 6.7e-41 ytzC S Protein of unknown function (DUF2524)
IIPAIDOJ_02131 5.1e-66 ytrA K GntR family transcriptional regulator
IIPAIDOJ_02132 1.6e-160 ytrB P abc transporter atp-binding protein
IIPAIDOJ_02133 2.2e-150 P ABC-2 family transporter protein
IIPAIDOJ_02134 4.8e-142
IIPAIDOJ_02135 9.1e-127 ytrE V ABC transporter, ATP-binding protein
IIPAIDOJ_02136 2.3e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
IIPAIDOJ_02137 1.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_02138 1.2e-185 T PhoQ Sensor
IIPAIDOJ_02139 7.3e-138 bceA V ABC transporter, ATP-binding protein
IIPAIDOJ_02140 0.0 bceB V ABC transporter (permease)
IIPAIDOJ_02141 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
IIPAIDOJ_02142 3.9e-210 yttB EGP Major facilitator Superfamily
IIPAIDOJ_02143 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IIPAIDOJ_02144 7.7e-55 ytvB S Protein of unknown function (DUF4257)
IIPAIDOJ_02145 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IIPAIDOJ_02146 2.1e-51 ytwF P Sulfurtransferase
IIPAIDOJ_02147 2.2e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IIPAIDOJ_02148 2.7e-96 amyC P ABC transporter (permease)
IIPAIDOJ_02149 6.2e-168 amyD P ABC transporter
IIPAIDOJ_02150 7.5e-244 msmE G Bacterial extracellular solute-binding protein
IIPAIDOJ_02151 5.6e-189 msmR K Transcriptional regulator
IIPAIDOJ_02152 1.1e-172 ytaP S Acetyl xylan esterase (AXE1)
IIPAIDOJ_02153 1.5e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IIPAIDOJ_02154 2.7e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IIPAIDOJ_02155 4.5e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IIPAIDOJ_02156 1.7e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IIPAIDOJ_02157 1.2e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IIPAIDOJ_02158 3.1e-220 bioI 1.14.14.46 C Cytochrome P450
IIPAIDOJ_02159 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
IIPAIDOJ_02160 2e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
IIPAIDOJ_02161 8.9e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
IIPAIDOJ_02162 0.0 ytdP K Transcriptional regulator
IIPAIDOJ_02163 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
IIPAIDOJ_02164 3e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IIPAIDOJ_02165 4.6e-73 yteS G transport
IIPAIDOJ_02166 2.5e-255 yteT S Oxidoreductase family, C-terminal alpha/beta domain
IIPAIDOJ_02167 9.1e-116 yteU S Integral membrane protein
IIPAIDOJ_02168 3.1e-26 yteV S Sporulation protein Cse60
IIPAIDOJ_02169 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
IIPAIDOJ_02170 8.2e-232 ytfP S HI0933-like protein
IIPAIDOJ_02171 4.7e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIPAIDOJ_02172 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IIPAIDOJ_02173 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
IIPAIDOJ_02174 1.3e-131 ythP V ABC transporter
IIPAIDOJ_02175 5.8e-203 ythQ U Bacterial ABC transporter protein EcsB
IIPAIDOJ_02176 7.2e-226 pbuO S permease
IIPAIDOJ_02177 5.6e-269 pepV 3.5.1.18 E Dipeptidase
IIPAIDOJ_02178 5.6e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IIPAIDOJ_02179 7.5e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IIPAIDOJ_02180 6.5e-165 ytlQ
IIPAIDOJ_02181 3.3e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IIPAIDOJ_02182 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
IIPAIDOJ_02183 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
IIPAIDOJ_02184 7.8e-45 ytzH S YtzH-like protein
IIPAIDOJ_02185 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IIPAIDOJ_02186 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
IIPAIDOJ_02187 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
IIPAIDOJ_02188 2.2e-51 ytzB S small secreted protein
IIPAIDOJ_02189 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IIPAIDOJ_02190 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
IIPAIDOJ_02191 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IIPAIDOJ_02192 9.8e-149 ytpQ S Belongs to the UPF0354 family
IIPAIDOJ_02193 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIPAIDOJ_02194 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IIPAIDOJ_02195 2.4e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IIPAIDOJ_02196 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IIPAIDOJ_02197 6.6e-17 ytxH S COG4980 Gas vesicle protein
IIPAIDOJ_02198 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
IIPAIDOJ_02199 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IIPAIDOJ_02200 3.8e-182 ccpA K catabolite control protein A
IIPAIDOJ_02201 2.1e-146 motA N flagellar motor
IIPAIDOJ_02202 1.2e-124 motS N Flagellar motor protein
IIPAIDOJ_02203 3.5e-224 acuC BQ histone deacetylase
IIPAIDOJ_02204 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
IIPAIDOJ_02205 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IIPAIDOJ_02206 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IIPAIDOJ_02207 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IIPAIDOJ_02209 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IIPAIDOJ_02210 2.4e-311 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
IIPAIDOJ_02211 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
IIPAIDOJ_02212 1e-108 yttP K Transcriptional regulator
IIPAIDOJ_02213 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IIPAIDOJ_02214 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IIPAIDOJ_02215 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
IIPAIDOJ_02216 3.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
IIPAIDOJ_02217 7.8e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIPAIDOJ_02218 2e-29 sspB S spore protein
IIPAIDOJ_02219 4.2e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IIPAIDOJ_02220 0.0 ytcJ S amidohydrolase
IIPAIDOJ_02221 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIPAIDOJ_02222 1.5e-178 sppA OU signal peptide peptidase SppA
IIPAIDOJ_02223 8.5e-87 yteJ S RDD family
IIPAIDOJ_02224 5.6e-116 ytfI S Protein of unknown function (DUF2953)
IIPAIDOJ_02225 8.7e-70 ytfJ S Sporulation protein YtfJ
IIPAIDOJ_02226 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IIPAIDOJ_02227 3.5e-164 ytxK 2.1.1.72 L DNA methylase
IIPAIDOJ_02228 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIPAIDOJ_02229 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IIPAIDOJ_02230 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IIPAIDOJ_02231 9.9e-266 argH 4.3.2.1 E argininosuccinate lyase
IIPAIDOJ_02233 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIPAIDOJ_02234 8.6e-130 ytkL S Belongs to the UPF0173 family
IIPAIDOJ_02235 7.2e-172 ytlI K LysR substrate binding domain
IIPAIDOJ_02236 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
IIPAIDOJ_02237 2.8e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
IIPAIDOJ_02238 2.2e-148 tcyK M Bacterial periplasmic substrate-binding proteins
IIPAIDOJ_02239 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
IIPAIDOJ_02240 4.6e-118 tcyM U Binding-protein-dependent transport system inner membrane component
IIPAIDOJ_02241 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IIPAIDOJ_02242 1.8e-184 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIPAIDOJ_02243 1.9e-46 ytnI O COG0695 Glutaredoxin and related proteins
IIPAIDOJ_02244 2.6e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIPAIDOJ_02245 3.4e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
IIPAIDOJ_02246 3.9e-237 ytnL 3.5.1.47 E hydrolase activity
IIPAIDOJ_02247 3.2e-156 ytnM S membrane transporter protein
IIPAIDOJ_02248 8e-241 ytoI K transcriptional regulator containing CBS domains
IIPAIDOJ_02249 2.4e-47 ytpI S YtpI-like protein
IIPAIDOJ_02250 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
IIPAIDOJ_02251 9.2e-29
IIPAIDOJ_02252 8.2e-69 ytrI
IIPAIDOJ_02253 3.2e-56 ytrH S Sporulation protein YtrH
IIPAIDOJ_02254 0.0 dnaE 2.7.7.7 L DNA polymerase
IIPAIDOJ_02255 3.4e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
IIPAIDOJ_02256 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IIPAIDOJ_02257 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IIPAIDOJ_02258 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IIPAIDOJ_02259 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IIPAIDOJ_02260 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
IIPAIDOJ_02261 3.4e-192 ytvI S sporulation integral membrane protein YtvI
IIPAIDOJ_02262 4.7e-71 yeaL S membrane
IIPAIDOJ_02263 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
IIPAIDOJ_02264 4.1e-242 icd 1.1.1.42 C isocitrate
IIPAIDOJ_02265 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
IIPAIDOJ_02266 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_02267 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
IIPAIDOJ_02268 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IIPAIDOJ_02269 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IIPAIDOJ_02270 1.1e-107 ytaF P Probably functions as a manganese efflux pump
IIPAIDOJ_02271 4.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IIPAIDOJ_02272 8.9e-161 ytbE S reductase
IIPAIDOJ_02273 2.4e-204 ytbD EGP Major facilitator Superfamily
IIPAIDOJ_02274 9.9e-67 ytcD K Transcriptional regulator
IIPAIDOJ_02275 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIPAIDOJ_02276 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IIPAIDOJ_02277 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IIPAIDOJ_02278 3.5e-266 dnaB L Membrane attachment protein
IIPAIDOJ_02279 1.1e-172 dnaI L Primosomal protein DnaI
IIPAIDOJ_02280 3.9e-108 ytxB S SNARE associated Golgi protein
IIPAIDOJ_02281 1.4e-158 ytxC S YtxC-like family
IIPAIDOJ_02283 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIPAIDOJ_02284 7.3e-149 ysaA S HAD-hyrolase-like
IIPAIDOJ_02285 0.0 lytS 2.7.13.3 T Histidine kinase
IIPAIDOJ_02286 2e-129 lytT T COG3279 Response regulator of the LytR AlgR family
IIPAIDOJ_02287 1.7e-49 lrgA S effector of murein hydrolase LrgA
IIPAIDOJ_02288 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IIPAIDOJ_02290 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IIPAIDOJ_02291 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IIPAIDOJ_02292 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IIPAIDOJ_02293 7.5e-45 ysdA S Membrane
IIPAIDOJ_02294 9.2e-68 ysdB S Sigma-w pathway protein YsdB
IIPAIDOJ_02295 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
IIPAIDOJ_02296 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IIPAIDOJ_02297 2.1e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IIPAIDOJ_02298 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
IIPAIDOJ_02299 3.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IIPAIDOJ_02300 4.3e-144 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IIPAIDOJ_02301 5.4e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IIPAIDOJ_02302 5.8e-252 araN G carbohydrate transport
IIPAIDOJ_02303 1.4e-167 araP G carbohydrate transport
IIPAIDOJ_02304 2.9e-143 araQ G transport system permease
IIPAIDOJ_02305 2.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
IIPAIDOJ_02306 0.0 cstA T Carbon starvation protein
IIPAIDOJ_02307 3.6e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
IIPAIDOJ_02308 2.4e-253 glcF C Glycolate oxidase
IIPAIDOJ_02309 2.3e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
IIPAIDOJ_02310 6.1e-202 ysfB KT regulator
IIPAIDOJ_02311 2.6e-32 sspI S Belongs to the SspI family
IIPAIDOJ_02312 1.2e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIPAIDOJ_02313 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IIPAIDOJ_02314 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIPAIDOJ_02315 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIPAIDOJ_02316 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IIPAIDOJ_02317 1.3e-85 cvpA S membrane protein, required for colicin V production
IIPAIDOJ_02318 0.0 polX L COG1796 DNA polymerase IV (family X)
IIPAIDOJ_02319 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IIPAIDOJ_02320 7.3e-68 yshE S membrane
IIPAIDOJ_02321 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IIPAIDOJ_02322 1.1e-98 fadR K Transcriptional regulator
IIPAIDOJ_02323 2e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IIPAIDOJ_02324 8.5e-134 etfB C Electron transfer flavoprotein
IIPAIDOJ_02325 1.1e-175 etfA C Electron transfer flavoprotein
IIPAIDOJ_02326 5e-300 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
IIPAIDOJ_02327 2e-52 trxA O Belongs to the thioredoxin family
IIPAIDOJ_02328 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IIPAIDOJ_02329 3.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IIPAIDOJ_02330 1.2e-79 yslB S Protein of unknown function (DUF2507)
IIPAIDOJ_02331 2.4e-107 sdhC C succinate dehydrogenase
IIPAIDOJ_02332 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IIPAIDOJ_02333 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IIPAIDOJ_02334 2.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
IIPAIDOJ_02335 3.3e-30 gerE K Transcriptional regulator
IIPAIDOJ_02336 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
IIPAIDOJ_02337 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IIPAIDOJ_02338 3.8e-196 gerM S COG5401 Spore germination protein
IIPAIDOJ_02339 1.2e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IIPAIDOJ_02340 2.2e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IIPAIDOJ_02341 3.1e-92 ysnB S Phosphoesterase
IIPAIDOJ_02343 5.5e-131 ysnF S protein conserved in bacteria
IIPAIDOJ_02344 1.4e-25 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IIPAIDOJ_02345 6.9e-150 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
IIPAIDOJ_02346 1.4e-75 ysnE K acetyltransferase
IIPAIDOJ_02348 0.0 ilvB 2.2.1.6 E Acetolactate synthase
IIPAIDOJ_02349 4.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
IIPAIDOJ_02350 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IIPAIDOJ_02351 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IIPAIDOJ_02352 2.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IIPAIDOJ_02353 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IIPAIDOJ_02354 1.8e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IIPAIDOJ_02355 2.3e-187 ysoA H Tetratricopeptide repeat
IIPAIDOJ_02356 4.1e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IIPAIDOJ_02357 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IIPAIDOJ_02358 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
IIPAIDOJ_02359 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IIPAIDOJ_02360 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
IIPAIDOJ_02361 1.4e-89 ysxD
IIPAIDOJ_02362 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IIPAIDOJ_02363 3.6e-146 hemX O cytochrome C
IIPAIDOJ_02364 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IIPAIDOJ_02365 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IIPAIDOJ_02366 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
IIPAIDOJ_02367 1.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IIPAIDOJ_02368 6.4e-222 spoVID M stage VI sporulation protein D
IIPAIDOJ_02369 2.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IIPAIDOJ_02370 1.6e-25
IIPAIDOJ_02371 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IIPAIDOJ_02372 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IIPAIDOJ_02373 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IIPAIDOJ_02374 2.7e-164 spoIIB S Sporulation related domain
IIPAIDOJ_02375 8.3e-102 maf D septum formation protein Maf
IIPAIDOJ_02376 5.9e-126 radC E Belongs to the UPF0758 family
IIPAIDOJ_02377 1.8e-184 mreB D Rod shape-determining protein MreB
IIPAIDOJ_02378 1.1e-156 mreC M Involved in formation and maintenance of cell shape
IIPAIDOJ_02379 1.4e-84 mreD M shape-determining protein
IIPAIDOJ_02380 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IIPAIDOJ_02381 2.5e-144 minD D Belongs to the ParA family
IIPAIDOJ_02382 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
IIPAIDOJ_02383 5.9e-160 spoIVFB S Stage IV sporulation protein
IIPAIDOJ_02384 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IIPAIDOJ_02385 4.1e-56 ysxB J ribosomal protein
IIPAIDOJ_02386 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IIPAIDOJ_02387 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
IIPAIDOJ_02388 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IIPAIDOJ_02389 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
IIPAIDOJ_02390 1.3e-162 pheA 4.2.1.51 E Prephenate dehydratase
IIPAIDOJ_02391 5.1e-93 niaR S small molecule binding protein (contains 3H domain)
IIPAIDOJ_02392 3.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
IIPAIDOJ_02393 3.9e-298 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
IIPAIDOJ_02394 2.8e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
IIPAIDOJ_02395 1.6e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IIPAIDOJ_02396 1.7e-157 safA M spore coat assembly protein SafA
IIPAIDOJ_02397 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IIPAIDOJ_02398 3.6e-126 yebC K transcriptional regulatory protein
IIPAIDOJ_02399 4.5e-261 alsT E Sodium alanine symporter
IIPAIDOJ_02400 8.1e-52 S Family of unknown function (DUF5412)
IIPAIDOJ_02402 7.2e-118 yrzF T serine threonine protein kinase
IIPAIDOJ_02403 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
IIPAIDOJ_02404 5.3e-253 csbX EGP Major facilitator Superfamily
IIPAIDOJ_02405 4.8e-93 bofC S BofC C-terminal domain
IIPAIDOJ_02406 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IIPAIDOJ_02407 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IIPAIDOJ_02408 6.9e-19 yrzS S Protein of unknown function (DUF2905)
IIPAIDOJ_02409 7.5e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IIPAIDOJ_02410 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IIPAIDOJ_02411 8e-39 yajC U Preprotein translocase subunit YajC
IIPAIDOJ_02412 1.2e-74 yrzE S Protein of unknown function (DUF3792)
IIPAIDOJ_02413 9.2e-113 yrbG S membrane
IIPAIDOJ_02414 8.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIPAIDOJ_02415 1.6e-48 yrzD S Post-transcriptional regulator
IIPAIDOJ_02416 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IIPAIDOJ_02417 1.9e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
IIPAIDOJ_02418 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
IIPAIDOJ_02419 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IIPAIDOJ_02420 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IIPAIDOJ_02421 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IIPAIDOJ_02422 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IIPAIDOJ_02423 2.2e-261 lytH 3.5.1.28 M COG3103 SH3 domain protein
IIPAIDOJ_02425 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
IIPAIDOJ_02426 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IIPAIDOJ_02427 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IIPAIDOJ_02428 2.2e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IIPAIDOJ_02429 1.2e-70 cymR K Transcriptional regulator
IIPAIDOJ_02430 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
IIPAIDOJ_02431 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IIPAIDOJ_02432 1.4e-15 S COG0457 FOG TPR repeat
IIPAIDOJ_02433 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IIPAIDOJ_02434 1.7e-81 yrrD S protein conserved in bacteria
IIPAIDOJ_02435 9.8e-31 yrzR
IIPAIDOJ_02436 8e-08 S Protein of unknown function (DUF3918)
IIPAIDOJ_02437 2.2e-106 glnP P ABC transporter
IIPAIDOJ_02438 1.8e-108 gluC P ABC transporter
IIPAIDOJ_02439 4.3e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
IIPAIDOJ_02440 1.2e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IIPAIDOJ_02441 2.7e-170 yrrI S AI-2E family transporter
IIPAIDOJ_02442 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IIPAIDOJ_02443 1.7e-41 yrzL S Belongs to the UPF0297 family
IIPAIDOJ_02444 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IIPAIDOJ_02445 1.2e-45 yrzB S Belongs to the UPF0473 family
IIPAIDOJ_02446 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IIPAIDOJ_02447 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
IIPAIDOJ_02448 3.3e-172 yegQ O Peptidase U32
IIPAIDOJ_02449 2.7e-246 yegQ O COG0826 Collagenase and related proteases
IIPAIDOJ_02450 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
IIPAIDOJ_02451 6.9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIPAIDOJ_02452 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
IIPAIDOJ_02453 4.2e-63 yrrS S Protein of unknown function (DUF1510)
IIPAIDOJ_02454 1e-25 yrzA S Protein of unknown function (DUF2536)
IIPAIDOJ_02455 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
IIPAIDOJ_02456 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IIPAIDOJ_02457 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
IIPAIDOJ_02458 2e-208 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IIPAIDOJ_02459 5.4e-78 yrhD S Protein of unknown function (DUF1641)
IIPAIDOJ_02460 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
IIPAIDOJ_02461 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
IIPAIDOJ_02462 6.7e-142 focA P Formate nitrite
IIPAIDOJ_02464 5.5e-95 yrhH Q methyltransferase
IIPAIDOJ_02465 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
IIPAIDOJ_02466 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IIPAIDOJ_02467 9.1e-44 yrhK S YrhK-like protein
IIPAIDOJ_02468 0.0 yrhL I Acyltransferase family
IIPAIDOJ_02469 5.5e-150 rsiV S Protein of unknown function (DUF3298)
IIPAIDOJ_02470 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IIPAIDOJ_02471 1.7e-148 yrhO K Archaeal transcriptional regulator TrmB
IIPAIDOJ_02472 1.1e-105 yrhP E LysE type translocator
IIPAIDOJ_02473 4.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
IIPAIDOJ_02474 0.0 levR K PTS system fructose IIA component
IIPAIDOJ_02475 1.1e-74 levD 2.7.1.202 G PTS system fructose IIA component
IIPAIDOJ_02476 6.9e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
IIPAIDOJ_02477 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IIPAIDOJ_02478 1.3e-151 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IIPAIDOJ_02479 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
IIPAIDOJ_02480 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
IIPAIDOJ_02481 2.1e-196 adhA 1.1.1.1 C alcohol dehydrogenase
IIPAIDOJ_02482 1.7e-46 yraB K helix_turn_helix, mercury resistance
IIPAIDOJ_02483 4.7e-48 yraD M Spore coat protein
IIPAIDOJ_02484 1.7e-25 yraE
IIPAIDOJ_02485 1.1e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IIPAIDOJ_02486 6.4e-63 yraF M Spore coat protein
IIPAIDOJ_02487 5.3e-37 yraG
IIPAIDOJ_02488 3e-63 E Glyoxalase-like domain
IIPAIDOJ_02489 5.4e-61 T sh3 domain protein
IIPAIDOJ_02490 2.2e-60 T sh3 domain protein
IIPAIDOJ_02491 1e-148 S Alpha beta hydrolase
IIPAIDOJ_02492 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIPAIDOJ_02493 6.5e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IIPAIDOJ_02494 1.1e-186 yrpG C Aldo/keto reductase family
IIPAIDOJ_02495 5.9e-94 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
IIPAIDOJ_02496 1.1e-112 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IIPAIDOJ_02497 2.8e-49 yjbR S YjbR
IIPAIDOJ_02498 7.2e-118 bmrR K helix_turn_helix, mercury resistance
IIPAIDOJ_02499 1.9e-98 flr S Flavin reductase like domain
IIPAIDOJ_02500 1.6e-123 yrpD S Domain of unknown function, YrpD
IIPAIDOJ_02501 3.8e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IIPAIDOJ_02502 9.3e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IIPAIDOJ_02503 5e-167 aadK G Streptomycin adenylyltransferase
IIPAIDOJ_02504 3.2e-89 yrdA S DinB family
IIPAIDOJ_02506 4e-55 S Protein of unknown function (DUF2568)
IIPAIDOJ_02507 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
IIPAIDOJ_02508 7.2e-74 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
IIPAIDOJ_02509 6.5e-130 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
IIPAIDOJ_02510 1.1e-251 cscA 3.2.1.26 GH32 G invertase
IIPAIDOJ_02511 2.1e-198 rafB P LacY proton/sugar symporter
IIPAIDOJ_02512 1.1e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
IIPAIDOJ_02513 3.9e-149 msmF P Binding-protein-dependent transport system inner membrane component
IIPAIDOJ_02514 2.6e-228 msmE G Bacterial extracellular solute-binding protein
IIPAIDOJ_02515 1.3e-163 scrR K transcriptional
IIPAIDOJ_02516 8.8e-64 K Transcriptional regulator
IIPAIDOJ_02517 7.5e-39 K Acetyltransferase (GNAT) family
IIPAIDOJ_02518 4.1e-223 cypA C Cytochrome P450
IIPAIDOJ_02519 8.3e-24 yrdF K ribonuclease inhibitor
IIPAIDOJ_02520 6.3e-79 bkdR K helix_turn_helix ASNC type
IIPAIDOJ_02521 9.6e-138 azlC E AzlC protein
IIPAIDOJ_02522 7.3e-50 azlD E Branched-chain amino acid transport protein (AzlD)
IIPAIDOJ_02523 3.5e-228 brnQ E Component of the transport system for branched-chain amino acids
IIPAIDOJ_02524 5.5e-161 gltR K LysR substrate binding domain
IIPAIDOJ_02525 6.5e-66 yodA S tautomerase
IIPAIDOJ_02526 2.3e-149 czcD P COG1230 Co Zn Cd efflux system component
IIPAIDOJ_02527 1.6e-196 trkA P Oxidoreductase
IIPAIDOJ_02528 3e-159 yrdQ K Transcriptional regulator
IIPAIDOJ_02529 6e-155 yrdR EG EamA-like transporter family
IIPAIDOJ_02530 3.9e-16 S YrzO-like protein
IIPAIDOJ_02531 5.1e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IIPAIDOJ_02532 4.5e-82 bltD 2.3.1.57 K FR47-like protein
IIPAIDOJ_02533 1.5e-209 blt EGP Major facilitator Superfamily
IIPAIDOJ_02534 6.5e-148 bltR K helix_turn_helix, mercury resistance
IIPAIDOJ_02535 4.9e-107 yrkC G Cupin domain
IIPAIDOJ_02536 5e-21
IIPAIDOJ_02537 7.8e-39 yrkD S protein conserved in bacteria
IIPAIDOJ_02538 7.3e-83 yrkE O DsrE/DsrF/DrsH-like family
IIPAIDOJ_02539 5.2e-46 P Rhodanese Homology Domain
IIPAIDOJ_02540 1.6e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
IIPAIDOJ_02541 7.1e-206 yrkH P Rhodanese Homology Domain
IIPAIDOJ_02542 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
IIPAIDOJ_02543 8.3e-113 yrkJ S membrane transporter protein
IIPAIDOJ_02544 1.9e-111 K COG1802 Transcriptional regulators
IIPAIDOJ_02545 1.7e-179 yjlA EG Putative multidrug resistance efflux transporter
IIPAIDOJ_02547 7.5e-80 S Protein of unknown function with HXXEE motif
IIPAIDOJ_02548 1.5e-97 ywrO S Flavodoxin-like fold
IIPAIDOJ_02549 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIPAIDOJ_02550 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
IIPAIDOJ_02551 4.1e-130 yqeB
IIPAIDOJ_02552 2.3e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
IIPAIDOJ_02553 6.7e-105 yqeD S SNARE associated Golgi protein
IIPAIDOJ_02554 5.4e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IIPAIDOJ_02555 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
IIPAIDOJ_02557 5.3e-95 yqeG S hydrolase of the HAD superfamily
IIPAIDOJ_02558 2.6e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IIPAIDOJ_02559 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IIPAIDOJ_02560 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
IIPAIDOJ_02561 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IIPAIDOJ_02562 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IIPAIDOJ_02563 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IIPAIDOJ_02564 1.1e-138 yqeM Q Methyltransferase
IIPAIDOJ_02565 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIPAIDOJ_02566 1.4e-94 wza L COG1555 DNA uptake protein and related DNA-binding proteins
IIPAIDOJ_02567 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
IIPAIDOJ_02568 0.0 comEC S Competence protein ComEC
IIPAIDOJ_02569 4.1e-15 S YqzM-like protein
IIPAIDOJ_02570 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
IIPAIDOJ_02571 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
IIPAIDOJ_02572 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IIPAIDOJ_02573 1.5e-222 spoIIP M stage II sporulation protein P
IIPAIDOJ_02574 3.6e-52 yqxA S Protein of unknown function (DUF3679)
IIPAIDOJ_02575 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IIPAIDOJ_02576 1.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
IIPAIDOJ_02577 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IIPAIDOJ_02578 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IIPAIDOJ_02579 0.0 dnaK O Heat shock 70 kDa protein
IIPAIDOJ_02580 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IIPAIDOJ_02581 5.4e-175 prmA J Methylates ribosomal protein L11
IIPAIDOJ_02582 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IIPAIDOJ_02583 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
IIPAIDOJ_02584 1.9e-156 yqeW P COG1283 Na phosphate symporter
IIPAIDOJ_02585 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IIPAIDOJ_02586 2.5e-61 yqeY S Yqey-like protein
IIPAIDOJ_02587 4.5e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
IIPAIDOJ_02588 3.7e-121 yqfA S UPF0365 protein
IIPAIDOJ_02589 1.7e-27 yqfB
IIPAIDOJ_02590 2.7e-45 yqfC S sporulation protein YqfC
IIPAIDOJ_02591 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
IIPAIDOJ_02592 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
IIPAIDOJ_02594 0.0 yqfF S membrane-associated HD superfamily hydrolase
IIPAIDOJ_02595 6.7e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IIPAIDOJ_02596 3e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IIPAIDOJ_02597 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IIPAIDOJ_02598 6.9e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IIPAIDOJ_02599 8.4e-19 S YqzL-like protein
IIPAIDOJ_02600 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
IIPAIDOJ_02601 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IIPAIDOJ_02602 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IIPAIDOJ_02603 4.5e-112 ccpN K CBS domain
IIPAIDOJ_02604 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IIPAIDOJ_02605 4.5e-88 yaiI S Belongs to the UPF0178 family
IIPAIDOJ_02606 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IIPAIDOJ_02607 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IIPAIDOJ_02608 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
IIPAIDOJ_02609 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
IIPAIDOJ_02610 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IIPAIDOJ_02611 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IIPAIDOJ_02612 7e-08 yqfQ S YqfQ-like protein
IIPAIDOJ_02613 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IIPAIDOJ_02614 5.7e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IIPAIDOJ_02615 2.1e-36 yqfT S Protein of unknown function (DUF2624)
IIPAIDOJ_02616 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IIPAIDOJ_02617 1.9e-77 zur P Belongs to the Fur family
IIPAIDOJ_02618 1.3e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
IIPAIDOJ_02619 4.3e-62 yqfX S membrane
IIPAIDOJ_02620 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IIPAIDOJ_02621 5.2e-47 yqfZ M LysM domain
IIPAIDOJ_02622 3.9e-131 yqgB S Protein of unknown function (DUF1189)
IIPAIDOJ_02623 4e-73 yqgC S protein conserved in bacteria
IIPAIDOJ_02624 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
IIPAIDOJ_02625 4.3e-231 yqgE EGP Major facilitator superfamily
IIPAIDOJ_02626 0.0 pbpA 3.4.16.4 M penicillin-binding protein
IIPAIDOJ_02627 6.2e-144 pstS P Phosphate
IIPAIDOJ_02628 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
IIPAIDOJ_02629 4.4e-158 pstA P Phosphate transport system permease
IIPAIDOJ_02630 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIPAIDOJ_02631 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIPAIDOJ_02632 7e-75 yqzC S YceG-like family
IIPAIDOJ_02633 9.2e-51 yqzD
IIPAIDOJ_02635 5.4e-195 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
IIPAIDOJ_02636 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IIPAIDOJ_02637 7.4e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IIPAIDOJ_02638 2.5e-09 yqgO
IIPAIDOJ_02639 7.3e-262 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IIPAIDOJ_02640 3.1e-33 yqgQ S Protein conserved in bacteria
IIPAIDOJ_02641 2e-180 glcK 2.7.1.2 G Glucokinase
IIPAIDOJ_02642 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IIPAIDOJ_02643 3.9e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
IIPAIDOJ_02644 3.3e-197 yqgU
IIPAIDOJ_02645 4.5e-49 yqgV S Thiamine-binding protein
IIPAIDOJ_02646 8.9e-23 yqgW S Protein of unknown function (DUF2759)
IIPAIDOJ_02647 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IIPAIDOJ_02648 1.8e-37 yqgY S Protein of unknown function (DUF2626)
IIPAIDOJ_02649 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
IIPAIDOJ_02651 2.7e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IIPAIDOJ_02652 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IIPAIDOJ_02653 4.7e-174 corA P Mg2 transporter protein
IIPAIDOJ_02655 1.9e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IIPAIDOJ_02656 1.5e-170 comGB NU COG1459 Type II secretory pathway, component PulF
IIPAIDOJ_02657 6.8e-47 comGC U Required for transformation and DNA binding
IIPAIDOJ_02658 5.4e-69 gspH NU protein transport across the cell outer membrane
IIPAIDOJ_02659 9e-59 comGE
IIPAIDOJ_02660 1.9e-33 comGF U Putative Competence protein ComGF
IIPAIDOJ_02661 1.2e-43 S ComG operon protein 7
IIPAIDOJ_02662 5.2e-26 yqzE S YqzE-like protein
IIPAIDOJ_02663 7.3e-54 yqzG S Protein of unknown function (DUF3889)
IIPAIDOJ_02664 1e-115 yqxM
IIPAIDOJ_02665 6.7e-59 sipW 3.4.21.89 U Signal peptidase
IIPAIDOJ_02666 5.6e-141 tasA S Cell division protein FtsN
IIPAIDOJ_02667 1e-54 sinR K transcriptional
IIPAIDOJ_02668 1.2e-24 sinI S Anti-repressor SinI
IIPAIDOJ_02669 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
IIPAIDOJ_02670 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IIPAIDOJ_02671 7.6e-205 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
IIPAIDOJ_02672 5.5e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IIPAIDOJ_02673 5.3e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IIPAIDOJ_02674 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
IIPAIDOJ_02675 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IIPAIDOJ_02676 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IIPAIDOJ_02677 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
IIPAIDOJ_02678 2.2e-61 yqhP
IIPAIDOJ_02679 2e-172 yqhQ S Protein of unknown function (DUF1385)
IIPAIDOJ_02680 6.6e-93 yqhR S Conserved membrane protein YqhR
IIPAIDOJ_02681 4.2e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
IIPAIDOJ_02682 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IIPAIDOJ_02683 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IIPAIDOJ_02684 7.9e-37 yqhV S Protein of unknown function (DUF2619)
IIPAIDOJ_02685 3e-170 spoIIIAA S stage III sporulation protein AA
IIPAIDOJ_02686 3.2e-84 spoIIIAB S Stage III sporulation protein
IIPAIDOJ_02687 7.6e-29 spoIIIAC S stage III sporulation protein AC
IIPAIDOJ_02688 2.3e-58 spoIIIAD S Stage III sporulation protein AD
IIPAIDOJ_02689 2.9e-197 spoIIIAE S stage III sporulation protein AE
IIPAIDOJ_02690 9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
IIPAIDOJ_02691 2.2e-109 spoIIIAG S stage III sporulation protein AG
IIPAIDOJ_02692 1.6e-85 spoIIIAH S SpoIIIAH-like protein
IIPAIDOJ_02693 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIPAIDOJ_02694 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IIPAIDOJ_02695 2.1e-67 yqhY S protein conserved in bacteria
IIPAIDOJ_02696 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IIPAIDOJ_02697 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IIPAIDOJ_02698 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIPAIDOJ_02699 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIPAIDOJ_02700 1.9e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IIPAIDOJ_02701 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IIPAIDOJ_02702 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
IIPAIDOJ_02703 1.7e-78 argR K Regulates arginine biosynthesis genes
IIPAIDOJ_02704 5.5e-306 recN L May be involved in recombinational repair of damaged DNA
IIPAIDOJ_02705 3.1e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
IIPAIDOJ_02706 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IIPAIDOJ_02708 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IIPAIDOJ_02709 6e-27
IIPAIDOJ_02710 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
IIPAIDOJ_02711 2.4e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IIPAIDOJ_02712 4.5e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
IIPAIDOJ_02713 7.5e-155 hbdA 1.1.1.157 I Dehydrogenase
IIPAIDOJ_02714 3.5e-208 mmgC I acyl-CoA dehydrogenase
IIPAIDOJ_02715 6.4e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
IIPAIDOJ_02716 6.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
IIPAIDOJ_02717 1.1e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IIPAIDOJ_02718 4e-34 yqzF S Protein of unknown function (DUF2627)
IIPAIDOJ_02719 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
IIPAIDOJ_02720 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
IIPAIDOJ_02721 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
IIPAIDOJ_02722 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
IIPAIDOJ_02723 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IIPAIDOJ_02724 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IIPAIDOJ_02725 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IIPAIDOJ_02726 4.9e-227 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIPAIDOJ_02727 5.8e-152 bmrR K helix_turn_helix, mercury resistance
IIPAIDOJ_02728 5.1e-207 norA EGP Major facilitator Superfamily
IIPAIDOJ_02729 2.6e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IIPAIDOJ_02730 9.3e-77 yqiW S Belongs to the UPF0403 family
IIPAIDOJ_02731 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
IIPAIDOJ_02732 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
IIPAIDOJ_02733 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IIPAIDOJ_02734 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
IIPAIDOJ_02735 2.2e-96 yqjB S protein conserved in bacteria
IIPAIDOJ_02737 2.3e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
IIPAIDOJ_02738 2e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IIPAIDOJ_02739 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
IIPAIDOJ_02740 5.4e-138 yqjF S Uncharacterized conserved protein (COG2071)
IIPAIDOJ_02741 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIPAIDOJ_02742 4.5e-24 yqzJ
IIPAIDOJ_02743 6.8e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIPAIDOJ_02744 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IIPAIDOJ_02745 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IIPAIDOJ_02746 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IIPAIDOJ_02747 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IIPAIDOJ_02748 4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IIPAIDOJ_02749 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IIPAIDOJ_02750 0.0 rocB E arginine degradation protein
IIPAIDOJ_02751 7.3e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIPAIDOJ_02752 2.7e-177 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
IIPAIDOJ_02753 1.3e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPAIDOJ_02754 1.5e-258 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IIPAIDOJ_02755 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
IIPAIDOJ_02756 2.1e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIPAIDOJ_02758 4.9e-224 yqjV G Major Facilitator Superfamily
IIPAIDOJ_02760 2e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIPAIDOJ_02761 3.7e-49 S YolD-like protein
IIPAIDOJ_02762 3.6e-87 yqjY K acetyltransferase
IIPAIDOJ_02763 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
IIPAIDOJ_02764 1.7e-193 yqkA K GrpB protein
IIPAIDOJ_02765 3.1e-53 yqkB S Belongs to the HesB IscA family
IIPAIDOJ_02766 9.4e-39 yqkC S Protein of unknown function (DUF2552)
IIPAIDOJ_02767 3.2e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
IIPAIDOJ_02768 3.1e-12 yqkE S Protein of unknown function (DUF3886)
IIPAIDOJ_02769 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
IIPAIDOJ_02771 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
IIPAIDOJ_02772 9e-220 yqxK 3.6.4.12 L DNA helicase
IIPAIDOJ_02773 4.5e-58 ansR K Transcriptional regulator
IIPAIDOJ_02774 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase
IIPAIDOJ_02775 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
IIPAIDOJ_02776 4.5e-234 mleN C Na H antiporter
IIPAIDOJ_02777 2.1e-241 mleA 1.1.1.38 C malic enzyme
IIPAIDOJ_02778 4.2e-30 yqkK
IIPAIDOJ_02779 2e-107 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IIPAIDOJ_02780 2.4e-80 fur P Belongs to the Fur family
IIPAIDOJ_02781 3.7e-37 S Protein of unknown function (DUF4227)
IIPAIDOJ_02782 2.6e-166 xerD L recombinase XerD
IIPAIDOJ_02783 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IIPAIDOJ_02784 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IIPAIDOJ_02785 5.3e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
IIPAIDOJ_02786 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
IIPAIDOJ_02787 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IIPAIDOJ_02788 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIPAIDOJ_02789 3.7e-111 spoVAA S Stage V sporulation protein AA
IIPAIDOJ_02790 1e-67 spoVAB S Stage V sporulation protein AB
IIPAIDOJ_02791 2.3e-78 spoVAC S stage V sporulation protein AC
IIPAIDOJ_02792 9e-192 spoVAD I Stage V sporulation protein AD
IIPAIDOJ_02793 2.2e-57 spoVAEB S stage V sporulation protein
IIPAIDOJ_02794 1.4e-110 spoVAEA S stage V sporulation protein
IIPAIDOJ_02795 1.4e-273 spoVAF EG Stage V sporulation protein AF
IIPAIDOJ_02796 3.4e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IIPAIDOJ_02797 3.6e-149 ypuA S Secreted protein
IIPAIDOJ_02798 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIPAIDOJ_02800 2.3e-08 eaeH M Domain of Unknown Function (DUF1259)
IIPAIDOJ_02802 2.5e-13 S PAP2 superfamily
IIPAIDOJ_02803 1.1e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
IIPAIDOJ_02804 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IIPAIDOJ_02805 1.3e-54 ypuD
IIPAIDOJ_02806 2.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IIPAIDOJ_02807 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
IIPAIDOJ_02808 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IIPAIDOJ_02809 1.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IIPAIDOJ_02810 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIPAIDOJ_02811 1e-90 ypuF S Domain of unknown function (DUF309)
IIPAIDOJ_02812 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IIPAIDOJ_02813 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IIPAIDOJ_02814 4e-98 ypuI S Protein of unknown function (DUF3907)
IIPAIDOJ_02815 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
IIPAIDOJ_02816 3.5e-103 spmA S Spore maturation protein
IIPAIDOJ_02817 1.9e-87 spmB S Spore maturation protein
IIPAIDOJ_02818 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IIPAIDOJ_02819 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IIPAIDOJ_02820 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
IIPAIDOJ_02821 1.7e-213 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IIPAIDOJ_02822 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_02823 0.0 resE 2.7.13.3 T Histidine kinase
IIPAIDOJ_02824 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
IIPAIDOJ_02825 4.1e-198 rsiX
IIPAIDOJ_02826 7.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IIPAIDOJ_02827 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIPAIDOJ_02828 2.2e-86 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IIPAIDOJ_02829 4.7e-41 fer C Ferredoxin
IIPAIDOJ_02830 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
IIPAIDOJ_02831 9.2e-286 recQ 3.6.4.12 L DNA helicase
IIPAIDOJ_02832 1.1e-99 ypbD S metal-dependent membrane protease
IIPAIDOJ_02833 2.9e-75 ypbE M Lysin motif
IIPAIDOJ_02834 2.8e-81 ypbF S Protein of unknown function (DUF2663)
IIPAIDOJ_02835 2.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
IIPAIDOJ_02836 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IIPAIDOJ_02837 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IIPAIDOJ_02838 6.2e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
IIPAIDOJ_02839 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
IIPAIDOJ_02840 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
IIPAIDOJ_02841 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
IIPAIDOJ_02842 6.6e-111 ypfA M Flagellar protein YcgR
IIPAIDOJ_02843 1.8e-23 S Family of unknown function (DUF5359)
IIPAIDOJ_02844 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IIPAIDOJ_02845 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
IIPAIDOJ_02846 1.2e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IIPAIDOJ_02847 1e-07 S YpzI-like protein
IIPAIDOJ_02848 8.7e-102 yphA
IIPAIDOJ_02849 2.5e-161 seaA S YIEGIA protein
IIPAIDOJ_02850 1.6e-28 ypzH
IIPAIDOJ_02851 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IIPAIDOJ_02852 1.6e-180 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IIPAIDOJ_02853 1.6e-18 yphE S Protein of unknown function (DUF2768)
IIPAIDOJ_02854 6e-137 yphF
IIPAIDOJ_02855 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IIPAIDOJ_02856 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IIPAIDOJ_02857 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
IIPAIDOJ_02858 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IIPAIDOJ_02859 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IIPAIDOJ_02860 7.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IIPAIDOJ_02861 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IIPAIDOJ_02862 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IIPAIDOJ_02863 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
IIPAIDOJ_02864 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IIPAIDOJ_02865 2.6e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IIPAIDOJ_02866 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IIPAIDOJ_02867 5.6e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IIPAIDOJ_02868 2.3e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IIPAIDOJ_02869 2.4e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IIPAIDOJ_02870 3e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IIPAIDOJ_02871 2.6e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IIPAIDOJ_02872 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IIPAIDOJ_02873 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IIPAIDOJ_02874 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IIPAIDOJ_02875 6.4e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IIPAIDOJ_02876 2.7e-233 S COG0457 FOG TPR repeat
IIPAIDOJ_02877 1.1e-98 ypiB S Belongs to the UPF0302 family
IIPAIDOJ_02878 1.2e-76 ypiF S Protein of unknown function (DUF2487)
IIPAIDOJ_02879 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
IIPAIDOJ_02880 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
IIPAIDOJ_02881 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
IIPAIDOJ_02882 5.2e-99 ypjA S membrane
IIPAIDOJ_02883 1e-142 ypjB S sporulation protein
IIPAIDOJ_02884 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
IIPAIDOJ_02885 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
IIPAIDOJ_02886 4.5e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IIPAIDOJ_02887 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
IIPAIDOJ_02888 1.7e-128 bshB1 S proteins, LmbE homologs
IIPAIDOJ_02889 3.4e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
IIPAIDOJ_02890 1.7e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IIPAIDOJ_02891 1.3e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IIPAIDOJ_02892 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IIPAIDOJ_02893 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IIPAIDOJ_02894 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IIPAIDOJ_02895 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IIPAIDOJ_02896 6.7e-23 ypmA S Protein of unknown function (DUF4264)
IIPAIDOJ_02897 2.2e-79 ypmB S protein conserved in bacteria
IIPAIDOJ_02898 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IIPAIDOJ_02899 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
IIPAIDOJ_02900 5.7e-129 dnaD L DNA replication protein DnaD
IIPAIDOJ_02901 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IIPAIDOJ_02902 1.4e-92 ypoC
IIPAIDOJ_02903 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
IIPAIDOJ_02904 4.6e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IIPAIDOJ_02905 3.1e-186 yppC S Protein of unknown function (DUF2515)
IIPAIDOJ_02908 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
IIPAIDOJ_02910 1e-47 yppG S YppG-like protein
IIPAIDOJ_02911 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
IIPAIDOJ_02912 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
IIPAIDOJ_02913 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IIPAIDOJ_02914 3.6e-235 yprB L RNase_H superfamily
IIPAIDOJ_02915 2.8e-91 ypsA S Belongs to the UPF0398 family
IIPAIDOJ_02916 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IIPAIDOJ_02917 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IIPAIDOJ_02919 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
IIPAIDOJ_02920 9.3e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIPAIDOJ_02921 2.2e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IIPAIDOJ_02922 1.5e-186 ptxS K transcriptional
IIPAIDOJ_02923 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
IIPAIDOJ_02924 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
IIPAIDOJ_02925 2.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IIPAIDOJ_02926 5.1e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IIPAIDOJ_02927 1.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IIPAIDOJ_02928 2.5e-226 pbuX F xanthine
IIPAIDOJ_02929 9.1e-206 bcsA Q Naringenin-chalcone synthase
IIPAIDOJ_02930 5.1e-87 ypbQ S protein conserved in bacteria
IIPAIDOJ_02932 0.0 ypbR S Dynamin family
IIPAIDOJ_02933 1e-38 ypbS S Protein of unknown function (DUF2533)
IIPAIDOJ_02934 2e-07
IIPAIDOJ_02935 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
IIPAIDOJ_02937 2.1e-67 rnhA 3.1.26.4 L Ribonuclease
IIPAIDOJ_02938 1e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IIPAIDOJ_02939 4.7e-135 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
IIPAIDOJ_02940 3e-29 ypeQ S Zinc-finger
IIPAIDOJ_02941 1.8e-30 S Protein of unknown function (DUF2564)
IIPAIDOJ_02942 3.8e-16 degR
IIPAIDOJ_02943 7.9e-31 cspD K Cold-shock protein
IIPAIDOJ_02944 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IIPAIDOJ_02946 8.1e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IIPAIDOJ_02947 1.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IIPAIDOJ_02948 5.6e-104 ypgQ S phosphohydrolase
IIPAIDOJ_02949 5.8e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
IIPAIDOJ_02950 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IIPAIDOJ_02951 1.7e-75 yphP S Belongs to the UPF0403 family
IIPAIDOJ_02952 2.9e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
IIPAIDOJ_02953 4.3e-112 ypjP S YpjP-like protein
IIPAIDOJ_02954 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
IIPAIDOJ_02955 5.3e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IIPAIDOJ_02956 1.5e-94 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IIPAIDOJ_02957 3.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IIPAIDOJ_02958 4.2e-110 hlyIII S protein, Hemolysin III
IIPAIDOJ_02959 5.9e-180 pspF K Transcriptional regulator
IIPAIDOJ_02960 3.5e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IIPAIDOJ_02961 8.9e-40 ypmP S Protein of unknown function (DUF2535)
IIPAIDOJ_02962 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IIPAIDOJ_02963 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
IIPAIDOJ_02964 1.1e-98 ypmS S protein conserved in bacteria
IIPAIDOJ_02965 1.2e-28 ypmT S Uncharacterized ympT
IIPAIDOJ_02966 3.8e-222 mepA V MATE efflux family protein
IIPAIDOJ_02967 1.6e-70 ypoP K transcriptional
IIPAIDOJ_02968 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIPAIDOJ_02969 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IIPAIDOJ_02970 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
IIPAIDOJ_02971 8.3e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
IIPAIDOJ_02972 6.9e-186 cgeB S Spore maturation protein
IIPAIDOJ_02973 1.2e-65 cgeA
IIPAIDOJ_02974 1e-37 cgeC
IIPAIDOJ_02975 4.7e-254 cgeD M maturation of the outermost layer of the spore
IIPAIDOJ_02976 1.8e-144 yiiD K acetyltransferase
IIPAIDOJ_02978 6.2e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IIPAIDOJ_02979 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IIPAIDOJ_02980 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IIPAIDOJ_02981 2.3e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
IIPAIDOJ_02982 5.1e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
IIPAIDOJ_02983 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
IIPAIDOJ_02984 2.9e-47 yokU S YokU-like protein, putative antitoxin
IIPAIDOJ_02985 1.4e-36 yozE S Belongs to the UPF0346 family
IIPAIDOJ_02986 6e-123 yodN
IIPAIDOJ_02988 2.8e-24 yozD S YozD-like protein
IIPAIDOJ_02989 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
IIPAIDOJ_02990 3.6e-54 yodL S YodL-like
IIPAIDOJ_02991 5.3e-09
IIPAIDOJ_02992 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IIPAIDOJ_02993 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IIPAIDOJ_02994 1.5e-23 yodI
IIPAIDOJ_02995 6.3e-128 yodH Q Methyltransferase
IIPAIDOJ_02996 1.8e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IIPAIDOJ_02997 9.3e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IIPAIDOJ_02998 6.2e-28 S Protein of unknown function (DUF3311)
IIPAIDOJ_02999 3.2e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
IIPAIDOJ_03000 5.5e-112 mhqD S Carboxylesterase
IIPAIDOJ_03001 1.4e-107 yodC C nitroreductase
IIPAIDOJ_03002 4.4e-55 yodB K transcriptional
IIPAIDOJ_03003 8e-64 yodA S tautomerase
IIPAIDOJ_03004 1.9e-205 gntP EG COG2610 H gluconate symporter and related permeases
IIPAIDOJ_03005 3.4e-09
IIPAIDOJ_03006 1.7e-60 yozR S COG0071 Molecular chaperone (small heat shock protein)
IIPAIDOJ_03007 5.6e-161 rarD S -transporter
IIPAIDOJ_03008 1.5e-43
IIPAIDOJ_03009 2.2e-60 yojF S Protein of unknown function (DUF1806)
IIPAIDOJ_03010 2.1e-125 yojG S deacetylase
IIPAIDOJ_03011 1.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IIPAIDOJ_03012 4.2e-245 norM V Multidrug efflux pump
IIPAIDOJ_03014 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIPAIDOJ_03015 3.4e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
IIPAIDOJ_03016 7.4e-196 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IIPAIDOJ_03017 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IIPAIDOJ_03018 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
IIPAIDOJ_03019 0.0 yojO P Von Willebrand factor
IIPAIDOJ_03020 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IIPAIDOJ_03021 9.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IIPAIDOJ_03022 1.1e-167 yocS S -transporter
IIPAIDOJ_03023 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IIPAIDOJ_03024 1.7e-164 sodA 1.15.1.1 P Superoxide dismutase
IIPAIDOJ_03025 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
IIPAIDOJ_03026 6.8e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
IIPAIDOJ_03027 2.7e-31 yozC
IIPAIDOJ_03028 4.2e-56 yozO S Bacterial PH domain
IIPAIDOJ_03029 1.9e-36 yocN
IIPAIDOJ_03030 1.1e-40 yozN
IIPAIDOJ_03031 2.2e-87 yocM O Belongs to the small heat shock protein (HSP20) family
IIPAIDOJ_03032 8.1e-32
IIPAIDOJ_03033 5.4e-53 yocL
IIPAIDOJ_03034 3.3e-83 dksA T general stress protein
IIPAIDOJ_03035 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IIPAIDOJ_03036 0.0 recQ 3.6.4.12 L DNA helicase
IIPAIDOJ_03037 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
IIPAIDOJ_03038 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIPAIDOJ_03039 7.1e-198 desK 2.7.13.3 T Histidine kinase
IIPAIDOJ_03040 5.9e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
IIPAIDOJ_03041 4.2e-186 yocD 3.4.17.13 V peptidase S66
IIPAIDOJ_03042 3.4e-91 yocC
IIPAIDOJ_03043 5.1e-142
IIPAIDOJ_03044 1.5e-92 yozB S membrane
IIPAIDOJ_03045 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IIPAIDOJ_03046 1e-51 czrA K transcriptional
IIPAIDOJ_03047 3e-93 yobW
IIPAIDOJ_03048 9.6e-172 yobV K WYL domain
IIPAIDOJ_03049 6.2e-82 yobU K Bacterial transcription activator, effector binding domain
IIPAIDOJ_03050 6.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
IIPAIDOJ_03051 1.3e-97 yobS K Transcriptional regulator
IIPAIDOJ_03052 4.5e-140 yobR 2.3.1.1 J FR47-like protein
IIPAIDOJ_03053 1.4e-133 yobQ K helix_turn_helix, arabinose operon control protein
IIPAIDOJ_03054 1.7e-51 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
IIPAIDOJ_03055 6e-274 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
IIPAIDOJ_03056 8.4e-99 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IIPAIDOJ_03057 1.7e-84 S SMI1-KNR4 cell-wall
IIPAIDOJ_03058 1.5e-11 S Domain of unknown function (DUF4879)
IIPAIDOJ_03060 6.7e-37
IIPAIDOJ_03061 7.3e-116
IIPAIDOJ_03066 1.7e-12 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
IIPAIDOJ_03067 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
IIPAIDOJ_03068 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
IIPAIDOJ_03071 1e-165 bla 3.5.2.6 V beta-lactamase
IIPAIDOJ_03072 7.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
IIPAIDOJ_03073 5.9e-76 yoaW
IIPAIDOJ_03074 1.1e-156 yijE EG EamA-like transporter family
IIPAIDOJ_03075 3.3e-158 yoaU K LysR substrate binding domain
IIPAIDOJ_03076 1.4e-147 yoaT S Protein of unknown function (DUF817)
IIPAIDOJ_03077 4.4e-30 yozG K Transcriptional regulator
IIPAIDOJ_03078 3.6e-74 yoaS S Protein of unknown function (DUF2975)
IIPAIDOJ_03079 7.1e-172 yoaR V vancomycin resistance protein
IIPAIDOJ_03080 3.1e-84
IIPAIDOJ_03083 4.6e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
IIPAIDOJ_03086 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
IIPAIDOJ_03087 4.7e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
IIPAIDOJ_03088 1.5e-110 yoaK S Membrane
IIPAIDOJ_03089 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
IIPAIDOJ_03090 1.8e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
IIPAIDOJ_03091 1.2e-180 mcpU NT methyl-accepting chemotaxis protein
IIPAIDOJ_03092 8.2e-37 S Protein of unknown function (DUF4025)
IIPAIDOJ_03093 2.6e-13
IIPAIDOJ_03094 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
IIPAIDOJ_03095 1.1e-33 yoaF
IIPAIDOJ_03096 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IIPAIDOJ_03097 4.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIPAIDOJ_03098 2e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
IIPAIDOJ_03099 1.2e-233 yoaB EGP Major facilitator Superfamily
IIPAIDOJ_03100 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
IIPAIDOJ_03101 3.3e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
IIPAIDOJ_03102 5.8e-95 V ABC-2 family transporter protein
IIPAIDOJ_03103 1.7e-126 V ABC-2 family transporter protein
IIPAIDOJ_03104 2.4e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IIPAIDOJ_03105 6.5e-134 yoxB
IIPAIDOJ_03106 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
IIPAIDOJ_03107 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPAIDOJ_03108 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IIPAIDOJ_03109 5.6e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIPAIDOJ_03110 4.6e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IIPAIDOJ_03111 7.8e-155 gltC K Transcriptional regulator
IIPAIDOJ_03112 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
IIPAIDOJ_03113 6.6e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IIPAIDOJ_03114 6.7e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IIPAIDOJ_03115 6.7e-156 gltR1 K Transcriptional regulator
IIPAIDOJ_03116 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IIPAIDOJ_03117 3e-34 yoeD G Helix-turn-helix domain
IIPAIDOJ_03118 2.2e-96 L Integrase
IIPAIDOJ_03120 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
IIPAIDOJ_03121 2.3e-246 yoeA V MATE efflux family protein
IIPAIDOJ_03122 1.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
IIPAIDOJ_03123 1.5e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
IIPAIDOJ_03124 6.1e-91 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPAIDOJ_03126 4.6e-157 ydhU P Catalase
IIPAIDOJ_03127 1.7e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
IIPAIDOJ_03128 1.7e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
IIPAIDOJ_03129 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
IIPAIDOJ_03130 2.1e-131 ydhQ K UTRA
IIPAIDOJ_03131 5.2e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPAIDOJ_03132 1.6e-233 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPAIDOJ_03133 1.3e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
IIPAIDOJ_03134 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
IIPAIDOJ_03135 1e-199 pbuE EGP Major facilitator Superfamily
IIPAIDOJ_03136 2.5e-98 ydhK M Protein of unknown function (DUF1541)
IIPAIDOJ_03137 4e-181 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IIPAIDOJ_03138 2.5e-83 K Acetyltransferase (GNAT) domain
IIPAIDOJ_03140 4.3e-67 frataxin S Domain of unknown function (DU1801)
IIPAIDOJ_03141 1.7e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
IIPAIDOJ_03142 2.5e-124
IIPAIDOJ_03143 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IIPAIDOJ_03144 1.1e-242 ydhD M Glycosyl hydrolase
IIPAIDOJ_03145 6.5e-122 ydhC K FCD
IIPAIDOJ_03146 1.2e-121 ydhB S membrane transporter protein
IIPAIDOJ_03147 2.2e-208 tcaB EGP Major facilitator Superfamily
IIPAIDOJ_03148 2.4e-69 ydgJ K Winged helix DNA-binding domain
IIPAIDOJ_03149 4e-113 drgA C nitroreductase
IIPAIDOJ_03150 0.0 ydgH S drug exporters of the RND superfamily
IIPAIDOJ_03151 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
IIPAIDOJ_03152 1.6e-88 dinB S DinB family
IIPAIDOJ_03153 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
IIPAIDOJ_03154 8.6e-301 expZ S ABC transporter
IIPAIDOJ_03155 4.6e-82 yycN 2.3.1.128 K Acetyltransferase
IIPAIDOJ_03156 7.3e-53 S DoxX-like family
IIPAIDOJ_03157 7.6e-98 K Bacterial regulatory proteins, tetR family
IIPAIDOJ_03158 2.7e-34 ydgB S Spore germination protein gerPA/gerPF
IIPAIDOJ_03159 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
IIPAIDOJ_03160 6.6e-67 cotP O Belongs to the small heat shock protein (HSP20) family
IIPAIDOJ_03161 1.5e-121 ydfS S Protein of unknown function (DUF421)
IIPAIDOJ_03162 8.4e-80 ydfR S Protein of unknown function (DUF421)
IIPAIDOJ_03164 9.3e-15 ydgA S Spore germination protein gerPA/gerPF
IIPAIDOJ_03165 2.6e-55 traF CO Thioredoxin
IIPAIDOJ_03166 1.2e-62 mhqP S DoxX
IIPAIDOJ_03167 1.9e-183 ydfO E COG0346 Lactoylglutathione lyase and related lyases
IIPAIDOJ_03168 2.8e-111 ydfN C nitroreductase
IIPAIDOJ_03169 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIPAIDOJ_03170 1.3e-146 K Bacterial transcription activator, effector binding domain
IIPAIDOJ_03171 6.5e-117 S Protein of unknown function (DUF554)
IIPAIDOJ_03172 1.6e-171 S Alpha/beta hydrolase family
IIPAIDOJ_03173 0.0 ydfJ S drug exporters of the RND superfamily
IIPAIDOJ_03174 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IIPAIDOJ_03175 2.9e-178 ydfH 2.7.13.3 T Histidine kinase
IIPAIDOJ_03177 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IIPAIDOJ_03178 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
IIPAIDOJ_03179 4.2e-115 ydfE S Flavin reductase like domain
IIPAIDOJ_03180 5.8e-184 gadB 4.1.1.105, 4.1.1.28, 4.1.1.29 E Pyridoxal-dependent decarboxylase conserved domain
IIPAIDOJ_03181 2.3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIPAIDOJ_03182 2.2e-149 ydfC EG EamA-like transporter family
IIPAIDOJ_03183 3.1e-122 T Transcriptional regulatory protein, C terminal
IIPAIDOJ_03184 1.8e-225 T GHKL domain
IIPAIDOJ_03185 2.3e-159
IIPAIDOJ_03186 2.7e-122 nodB1 G deacetylase
IIPAIDOJ_03187 1.1e-148 lytR K Transcriptional regulator
IIPAIDOJ_03188 3.5e-143 ydfB J GNAT acetyltransferase
IIPAIDOJ_03189 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IIPAIDOJ_03190 2.8e-57 arsR K transcriptional
IIPAIDOJ_03191 3.2e-104 ydeS K Transcriptional regulator
IIPAIDOJ_03192 4.3e-193 ydeR EGP Major facilitator Superfamily
IIPAIDOJ_03193 1.6e-48 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
IIPAIDOJ_03194 7.2e-39 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
IIPAIDOJ_03195 1.5e-67 ydeP K Transcriptional regulator
IIPAIDOJ_03196 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IIPAIDOJ_03197 8.9e-56 K HxlR-like helix-turn-helix
IIPAIDOJ_03198 2.6e-103 ydeN S Serine hydrolase
IIPAIDOJ_03199 1.3e-72 maoC I N-terminal half of MaoC dehydratase
IIPAIDOJ_03200 1.6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIPAIDOJ_03201 1.8e-153 ydeK EG -transporter
IIPAIDOJ_03202 2.6e-84 K Transcriptional regulator C-terminal region
IIPAIDOJ_03203 4.9e-15 ptsH G PTS HPr component phosphorylation site
IIPAIDOJ_03204 1.1e-31 S SNARE associated Golgi protein
IIPAIDOJ_03205 9.1e-100
IIPAIDOJ_03206 2.1e-103 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
IIPAIDOJ_03207 1e-216 ydeG EGP Major facilitator superfamily
IIPAIDOJ_03208 3.6e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIPAIDOJ_03209 9e-164 ydeE K AraC family transcriptional regulator
IIPAIDOJ_03210 1.1e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IIPAIDOJ_03211 2e-163 rhaS5 K AraC-like ligand binding domain
IIPAIDOJ_03212 1.2e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IIPAIDOJ_03213 2.3e-78 carD K Transcription factor
IIPAIDOJ_03214 8.7e-30 cspL K Cold shock
IIPAIDOJ_03215 2.4e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
IIPAIDOJ_03216 9.6e-40
IIPAIDOJ_03217 3.4e-33 K Helix-turn-helix XRE-family like proteins
IIPAIDOJ_03218 2.1e-46 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
IIPAIDOJ_03219 5e-47 ydeH
IIPAIDOJ_03220 6.9e-208 msbA2 3.6.3.44 V ABC transporter
IIPAIDOJ_03221 5.8e-211 KLT Protein kinase domain
IIPAIDOJ_03226 1.3e-157 KLT Protein kinase domain
IIPAIDOJ_03237 8.9e-83 ydcK S Belongs to the SprT family
IIPAIDOJ_03238 0.0 yhgF K COG2183 Transcriptional accessory protein
IIPAIDOJ_03239 2.3e-75 ydcH K helix_turn_helix multiple antibiotic resistance protein
IIPAIDOJ_03240 4.3e-82 ydcG S EVE domain
IIPAIDOJ_03241 1.7e-14 S Polyketide cyclase / dehydrase and lipid transport
IIPAIDOJ_03242 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
IIPAIDOJ_03243 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IIPAIDOJ_03244 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IIPAIDOJ_03245 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
IIPAIDOJ_03246 7.1e-189 rsbU 3.1.3.3 KT phosphatase
IIPAIDOJ_03247 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IIPAIDOJ_03248 5.2e-57 rsbS T antagonist
IIPAIDOJ_03249 1.1e-142 rsbR T Positive regulator of sigma-B
IIPAIDOJ_03250 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
IIPAIDOJ_03251 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IIPAIDOJ_03252 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIPAIDOJ_03253 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
IIPAIDOJ_03254 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IIPAIDOJ_03255 5.8e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
IIPAIDOJ_03256 5.6e-259 ydbT S Membrane
IIPAIDOJ_03257 2.8e-82 ydbS S Bacterial PH domain
IIPAIDOJ_03258 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IIPAIDOJ_03259 3.7e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IIPAIDOJ_03260 1.1e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IIPAIDOJ_03261 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IIPAIDOJ_03262 1.3e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIPAIDOJ_03263 2.2e-07 S Fur-regulated basic protein A
IIPAIDOJ_03264 1.1e-18 S Fur-regulated basic protein B
IIPAIDOJ_03265 3.7e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
IIPAIDOJ_03266 2.7e-52 ydbL
IIPAIDOJ_03267 2.1e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IIPAIDOJ_03268 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
IIPAIDOJ_03269 4.4e-181 ydbI S AI-2E family transporter
IIPAIDOJ_03270 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIPAIDOJ_03271 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
IIPAIDOJ_03272 1.8e-295 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IIPAIDOJ_03273 4.3e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IIPAIDOJ_03274 2.3e-153 ydbD P Catalase
IIPAIDOJ_03275 2.8e-63 ydbC S Domain of unknown function (DUF4937
IIPAIDOJ_03276 8.9e-59 ydbB G Cupin domain
IIPAIDOJ_03278 1.8e-145 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
IIPAIDOJ_03279 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
IIPAIDOJ_03281 3.9e-224 mntH P H( )-stimulated, divalent metal cation uptake system
IIPAIDOJ_03282 2.1e-39
IIPAIDOJ_03284 1.8e-72 sdpB S Protein conserved in bacteria
IIPAIDOJ_03285 1.8e-27
IIPAIDOJ_03287 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IIPAIDOJ_03288 3.6e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IIPAIDOJ_03289 0.0 ydaO E amino acid
IIPAIDOJ_03290 0.0 ydaN S Bacterial cellulose synthase subunit
IIPAIDOJ_03291 4.5e-233 ydaM M Glycosyl transferase family group 2
IIPAIDOJ_03292 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
IIPAIDOJ_03293 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
IIPAIDOJ_03294 2.1e-207 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
IIPAIDOJ_03295 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIPAIDOJ_03296 2.5e-74 lrpC K Transcriptional regulator
IIPAIDOJ_03297 3.6e-45 ydzA EGP Major facilitator Superfamily
IIPAIDOJ_03298 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IIPAIDOJ_03299 6.8e-77 ydaG 1.4.3.5 S general stress protein
IIPAIDOJ_03300 1.6e-97 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IIPAIDOJ_03301 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
IIPAIDOJ_03302 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIPAIDOJ_03303 4.9e-97 ydaC Q Methyltransferase domain
IIPAIDOJ_03304 1.2e-293 ydaB IQ acyl-CoA ligase
IIPAIDOJ_03305 0.0 mtlR K transcriptional regulator, MtlR
IIPAIDOJ_03306 8.1e-176 ydhF S Oxidoreductase
IIPAIDOJ_03307 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
IIPAIDOJ_03308 8e-47 yczJ S biosynthesis
IIPAIDOJ_03310 3.5e-117 ycsK E anatomical structure formation involved in morphogenesis
IIPAIDOJ_03311 2.7e-132 kipR K Transcriptional regulator
IIPAIDOJ_03312 6.2e-185 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
IIPAIDOJ_03313 1e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
IIPAIDOJ_03314 2.4e-147 ycsI S Belongs to the D-glutamate cyclase family
IIPAIDOJ_03315 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
IIPAIDOJ_03316 1.8e-139 ycsF S Belongs to the UPF0271 (lamB) family
IIPAIDOJ_03317 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IIPAIDOJ_03319 1.6e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IIPAIDOJ_03320 7e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
IIPAIDOJ_03321 3.6e-72 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IIPAIDOJ_03323 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
IIPAIDOJ_03324 2.8e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
IIPAIDOJ_03325 4.4e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IIPAIDOJ_03326 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
IIPAIDOJ_03327 2.6e-53
IIPAIDOJ_03328 4.7e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
IIPAIDOJ_03329 1.5e-305 ycnJ P protein, homolog of Cu resistance protein CopC
IIPAIDOJ_03330 9.3e-99 ycnI S protein conserved in bacteria
IIPAIDOJ_03331 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIPAIDOJ_03332 6.1e-149 glcU U Glucose uptake
IIPAIDOJ_03333 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IIPAIDOJ_03334 8.2e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IIPAIDOJ_03335 2.6e-269 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IIPAIDOJ_03336 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
IIPAIDOJ_03337 1.6e-45 ycnE S Monooxygenase
IIPAIDOJ_03338 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
IIPAIDOJ_03339 6.5e-154 ycnC K Transcriptional regulator
IIPAIDOJ_03340 3.5e-250 ycnB EGP Major facilitator Superfamily
IIPAIDOJ_03341 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
IIPAIDOJ_03342 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
IIPAIDOJ_03343 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_03344 4.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_03345 7.5e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
IIPAIDOJ_03349 2e-70 S aspartate phosphatase
IIPAIDOJ_03350 4.4e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IIPAIDOJ_03351 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_03352 2e-200 yclI V ABC transporter (permease) YclI
IIPAIDOJ_03353 1.9e-121 yclH P ABC transporter
IIPAIDOJ_03354 9.3e-198 gerKB F Spore germination protein
IIPAIDOJ_03355 6.3e-232 gerKC S spore germination
IIPAIDOJ_03356 4.1e-279 gerKA EG Spore germination protein
IIPAIDOJ_03358 4.5e-308 yclG M Pectate lyase superfamily protein
IIPAIDOJ_03359 3.3e-267 dtpT E amino acid peptide transporter
IIPAIDOJ_03360 7.8e-157 yclE 3.4.11.5 S Alpha beta hydrolase
IIPAIDOJ_03361 2.5e-80 yclD
IIPAIDOJ_03362 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
IIPAIDOJ_03363 4.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IIPAIDOJ_03364 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IIPAIDOJ_03365 1.9e-161 bsdA K LysR substrate binding domain
IIPAIDOJ_03366 6.4e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IIPAIDOJ_03367 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
IIPAIDOJ_03368 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IIPAIDOJ_03369 9.7e-115 yczE S membrane
IIPAIDOJ_03370 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IIPAIDOJ_03371 1.4e-248 ycxD K GntR family transcriptional regulator
IIPAIDOJ_03372 6.9e-162 ycxC EG EamA-like transporter family
IIPAIDOJ_03373 1.3e-88 S YcxB-like protein
IIPAIDOJ_03374 5.9e-222 EGP Major Facilitator Superfamily
IIPAIDOJ_03375 2.9e-139 srfAD Q thioesterase
IIPAIDOJ_03376 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
IIPAIDOJ_03377 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPAIDOJ_03378 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPAIDOJ_03379 1.3e-63 hxlR K transcriptional
IIPAIDOJ_03380 1.8e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
IIPAIDOJ_03381 1.1e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
IIPAIDOJ_03382 1.2e-183 tlpC 2.7.13.3 NT chemotaxis protein
IIPAIDOJ_03383 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
IIPAIDOJ_03384 1.1e-68 nin S Competence protein J (ComJ)
IIPAIDOJ_03385 1.5e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPAIDOJ_03386 7.8e-52 yckD S Protein of unknown function (DUF2680)
IIPAIDOJ_03387 3.1e-75 yckC S membrane
IIPAIDOJ_03389 1.7e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IIPAIDOJ_03390 1.2e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
IIPAIDOJ_03391 5e-226 yciC S GTPases (G3E family)
IIPAIDOJ_03392 5.1e-107 yciB M ErfK YbiS YcfS YnhG
IIPAIDOJ_03393 3.5e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
IIPAIDOJ_03394 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
IIPAIDOJ_03395 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
IIPAIDOJ_03396 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IIPAIDOJ_03397 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IIPAIDOJ_03398 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
IIPAIDOJ_03399 6e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IIPAIDOJ_03400 6e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IIPAIDOJ_03401 3.2e-158 I alpha/beta hydrolase fold
IIPAIDOJ_03402 7e-140 ycgR S permeases
IIPAIDOJ_03403 2.2e-146 ycgQ S membrane
IIPAIDOJ_03404 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
IIPAIDOJ_03405 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IIPAIDOJ_03406 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IIPAIDOJ_03407 5.1e-170 ycgM E Proline dehydrogenase
IIPAIDOJ_03408 6.4e-145 ycgL S Predicted nucleotidyltransferase
IIPAIDOJ_03409 1.6e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
IIPAIDOJ_03410 1.2e-177 oxyR3 K LysR substrate binding domain
IIPAIDOJ_03411 9e-144 yafE Q ubiE/COQ5 methyltransferase family
IIPAIDOJ_03412 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IIPAIDOJ_03413 4.7e-108 tmrB S AAA domain
IIPAIDOJ_03414 2.6e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IIPAIDOJ_03415 2.4e-112 ycgI S Domain of unknown function (DUF1989)
IIPAIDOJ_03416 6.2e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
IIPAIDOJ_03417 1.2e-151 yqcI S YqcI/YcgG family
IIPAIDOJ_03418 6.8e-113 ycgF E Lysine exporter protein LysE YggA
IIPAIDOJ_03419 1.3e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
IIPAIDOJ_03420 3.9e-263 mdr EGP Major facilitator Superfamily
IIPAIDOJ_03421 2e-289 lctP C L-lactate permease
IIPAIDOJ_03422 9.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IIPAIDOJ_03423 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
IIPAIDOJ_03424 4.5e-80 ycgB
IIPAIDOJ_03425 4.7e-255 ycgA S Membrane
IIPAIDOJ_03426 5e-215 amhX S amidohydrolase
IIPAIDOJ_03427 5.3e-164 opuAC E glycine betaine
IIPAIDOJ_03428 1.3e-127 opuAB P glycine betaine
IIPAIDOJ_03429 4.3e-228 proV 3.6.3.32 E glycine betaine
IIPAIDOJ_03430 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
IIPAIDOJ_03431 2.2e-205 yceJ EGP Uncharacterised MFS-type transporter YbfB
IIPAIDOJ_03432 4.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
IIPAIDOJ_03433 2e-192 yceH P Belongs to the TelA family
IIPAIDOJ_03434 0.0 yceG S Putative component of 'biosynthetic module'
IIPAIDOJ_03435 6.3e-137 terC P Protein of unknown function (DUF475)
IIPAIDOJ_03436 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
IIPAIDOJ_03437 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
IIPAIDOJ_03438 1.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
IIPAIDOJ_03439 4e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IIPAIDOJ_03440 1.9e-134 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IIPAIDOJ_03441 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IIPAIDOJ_03442 2.5e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
IIPAIDOJ_03443 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
IIPAIDOJ_03444 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
IIPAIDOJ_03445 1.2e-173 S response regulator aspartate phosphatase
IIPAIDOJ_03446 1.3e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
IIPAIDOJ_03447 2.2e-255 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
IIPAIDOJ_03448 8e-271 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
IIPAIDOJ_03449 6.6e-177 ycdA S Domain of unknown function (DUF5105)
IIPAIDOJ_03450 5.6e-172 yccK C Aldo keto reductase
IIPAIDOJ_03451 1.3e-199 natB CP ABC-2 family transporter protein
IIPAIDOJ_03452 1.3e-131 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
IIPAIDOJ_03453 1.2e-126 lytR_2 T LytTr DNA-binding domain
IIPAIDOJ_03454 3.9e-152 2.7.13.3 T GHKL domain
IIPAIDOJ_03455 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
IIPAIDOJ_03456 3.4e-59 S RDD family
IIPAIDOJ_03457 9.3e-102 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
IIPAIDOJ_03458 4.2e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IIPAIDOJ_03459 7e-101 yxaF K Transcriptional regulator
IIPAIDOJ_03460 7.6e-229 lmrB EGP the major facilitator superfamily
IIPAIDOJ_03461 1.1e-198 ycbU E Selenocysteine lyase
IIPAIDOJ_03462 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IIPAIDOJ_03463 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IIPAIDOJ_03464 1.3e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IIPAIDOJ_03465 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
IIPAIDOJ_03467 9.5e-135 ycbR T vWA found in TerF C terminus
IIPAIDOJ_03468 2.2e-78 sleB 3.5.1.28 M Cell wall
IIPAIDOJ_03469 4.1e-52 ycbP S Protein of unknown function (DUF2512)
IIPAIDOJ_03470 1.1e-113 S ABC-2 family transporter protein
IIPAIDOJ_03471 4.5e-166 ycbN V ABC transporter, ATP-binding protein
IIPAIDOJ_03472 1.2e-166 T PhoQ Sensor
IIPAIDOJ_03473 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IIPAIDOJ_03474 1.5e-169 eamA1 EG spore germination
IIPAIDOJ_03475 5.7e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
IIPAIDOJ_03476 2.2e-176 ycbJ S Macrolide 2'-phosphotransferase
IIPAIDOJ_03477 3.3e-294 garD 4.2.1.42, 4.2.1.7 G Altronate
IIPAIDOJ_03478 6.1e-123 ycbG K FCD
IIPAIDOJ_03479 2.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IIPAIDOJ_03480 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
IIPAIDOJ_03481 3.4e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IIPAIDOJ_03482 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
IIPAIDOJ_03483 9e-170 glnL T Regulator
IIPAIDOJ_03484 3.6e-228 phoQ 2.7.13.3 T Histidine kinase
IIPAIDOJ_03485 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
IIPAIDOJ_03486 9.6e-256 agcS E Sodium alanine symporter
IIPAIDOJ_03487 2.4e-178 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
IIPAIDOJ_03488 5.7e-261 mmuP E amino acid
IIPAIDOJ_03489 2e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IIPAIDOJ_03491 4.9e-128 K UTRA
IIPAIDOJ_03492 3.4e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IIPAIDOJ_03493 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IIPAIDOJ_03494 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIPAIDOJ_03495 3.9e-192 yceA S Belongs to the UPF0176 family
IIPAIDOJ_03496 1e-251 S Erythromycin esterase
IIPAIDOJ_03497 4.6e-45 ybfN
IIPAIDOJ_03498 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IIPAIDOJ_03499 2.7e-85 ybfM S SNARE associated Golgi protein
IIPAIDOJ_03500 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIPAIDOJ_03501 1.1e-164 S Alpha/beta hydrolase family
IIPAIDOJ_03503 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
IIPAIDOJ_03504 1.4e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IIPAIDOJ_03505 2e-144 msmR K AraC-like ligand binding domain
IIPAIDOJ_03506 2.4e-159 ybfH EG EamA-like transporter family
IIPAIDOJ_03507 0.0 ybfG M Domain of unknown function (DUF1906)
IIPAIDOJ_03509 6e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
IIPAIDOJ_03510 8.2e-168 ybfA 3.4.15.5 K FR47-like protein
IIPAIDOJ_03511 5.5e-34 S Protein of unknown function (DUF2651)
IIPAIDOJ_03512 9.5e-258 glpT G -transporter
IIPAIDOJ_03513 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IIPAIDOJ_03514 1.8e-290 ybeC E amino acid
IIPAIDOJ_03515 4.9e-41 ybyB
IIPAIDOJ_03516 2.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
IIPAIDOJ_03517 2e-107 ybxI 3.5.2.6 V beta-lactamase
IIPAIDOJ_03518 4.9e-30 ybxH S Family of unknown function (DUF5370)
IIPAIDOJ_03519 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
IIPAIDOJ_03520 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
IIPAIDOJ_03521 9.8e-214 ybdO S Domain of unknown function (DUF4885)
IIPAIDOJ_03522 1.2e-152 ybdN
IIPAIDOJ_03523 6.1e-140 KLT Protein tyrosine kinase
IIPAIDOJ_03525 1.1e-170 T His Kinase A (phospho-acceptor) domain
IIPAIDOJ_03526 8.5e-122 T Transcriptional regulatory protein, C terminal
IIPAIDOJ_03527 1.9e-178 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IIPAIDOJ_03528 2.5e-56
IIPAIDOJ_03529 1.3e-202 ybcL EGP Major facilitator Superfamily
IIPAIDOJ_03530 5.1e-50 ybzH K Helix-turn-helix domain
IIPAIDOJ_03531 3.2e-59 ybcI S Uncharacterized conserved protein (DUF2294)
IIPAIDOJ_03532 1.9e-46
IIPAIDOJ_03534 2.2e-93 can 4.2.1.1 P carbonic anhydrase
IIPAIDOJ_03535 0.0 ybcC S Belongs to the UPF0753 family
IIPAIDOJ_03536 2.4e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IIPAIDOJ_03537 1.6e-99 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IIPAIDOJ_03538 6.4e-119 adaA 3.2.2.21 K Transcriptional regulator
IIPAIDOJ_03539 2e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IIPAIDOJ_03541 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IIPAIDOJ_03542 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IIPAIDOJ_03543 5.7e-224 ybbR S protein conserved in bacteria
IIPAIDOJ_03544 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIPAIDOJ_03545 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IIPAIDOJ_03546 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
IIPAIDOJ_03552 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
IIPAIDOJ_03553 1.9e-86 ybbJ J acetyltransferase
IIPAIDOJ_03554 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IIPAIDOJ_03555 3.6e-149 ybbH K transcriptional
IIPAIDOJ_03556 1.1e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IIPAIDOJ_03557 4.5e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
IIPAIDOJ_03558 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
IIPAIDOJ_03559 2.1e-238 ybbC 3.2.1.52 S protein conserved in bacteria
IIPAIDOJ_03560 2e-302 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
IIPAIDOJ_03561 4e-165 feuA P Iron-uptake system-binding protein
IIPAIDOJ_03562 5.3e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_03563 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_03564 2.7e-140 ybbA S Putative esterase
IIPAIDOJ_03565 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
IIPAIDOJ_03566 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
IIPAIDOJ_03568 4.9e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IIPAIDOJ_03569 5.2e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
IIPAIDOJ_03570 4.5e-126 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
IIPAIDOJ_03571 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IIPAIDOJ_03572 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IIPAIDOJ_03573 0.0 ydiF S ABC transporter
IIPAIDOJ_03574 7.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IIPAIDOJ_03575 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IIPAIDOJ_03576 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IIPAIDOJ_03577 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IIPAIDOJ_03578 2.9e-27 ydiK S Domain of unknown function (DUF4305)
IIPAIDOJ_03579 7.9e-129 ydiL S CAAX protease self-immunity
IIPAIDOJ_03580 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IIPAIDOJ_03581 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IIPAIDOJ_03582 1.5e-70 L Belongs to the 'phage' integrase family
IIPAIDOJ_03583 3.5e-16 L Belongs to the 'phage' integrase family
IIPAIDOJ_03586 4.6e-24 C 4Fe-4S single cluster domain
IIPAIDOJ_03588 3.7e-21 S Peptidase_C39 like family
IIPAIDOJ_03591 1.3e-51 2.7.7.49 L reverse transcriptase
IIPAIDOJ_03592 0.0 K NB-ARC domain
IIPAIDOJ_03593 4.7e-199 gutB 1.1.1.14 E Dehydrogenase
IIPAIDOJ_03594 2.1e-252 gutA G MFS/sugar transport protein
IIPAIDOJ_03595 6.8e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
IIPAIDOJ_03596 2.5e-113 pspA KT Phage shock protein A
IIPAIDOJ_03597 1.7e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIPAIDOJ_03598 1.9e-133 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
IIPAIDOJ_03599 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
IIPAIDOJ_03600 6.7e-195 S Ion transport 2 domain protein
IIPAIDOJ_03601 8.6e-257 iolT EGP Major facilitator Superfamily
IIPAIDOJ_03602 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
IIPAIDOJ_03603 4.5e-64 ydjM M Lytic transglycolase
IIPAIDOJ_03604 1.1e-155 ydjN U Involved in the tonB-independent uptake of proteins
IIPAIDOJ_03606 1.2e-34 ydjO S Cold-inducible protein YdjO
IIPAIDOJ_03607 2.6e-157 ydjP I Alpha/beta hydrolase family
IIPAIDOJ_03608 1.6e-177 yeaA S Protein of unknown function (DUF4003)
IIPAIDOJ_03609 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
IIPAIDOJ_03610 7.5e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
IIPAIDOJ_03611 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIPAIDOJ_03612 4.3e-175 yeaC S COG0714 MoxR-like ATPases
IIPAIDOJ_03613 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IIPAIDOJ_03614 0.0 yebA E COG1305 Transglutaminase-like enzymes
IIPAIDOJ_03615 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IIPAIDOJ_03616 1e-211 pbuG S permease
IIPAIDOJ_03617 5.8e-117 yebC M Membrane
IIPAIDOJ_03619 8.9e-93 yebE S UPF0316 protein
IIPAIDOJ_03620 8e-28 yebG S NETI protein
IIPAIDOJ_03621 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IIPAIDOJ_03622 5.9e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IIPAIDOJ_03623 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IIPAIDOJ_03624 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IIPAIDOJ_03625 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIPAIDOJ_03626 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIPAIDOJ_03627 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIPAIDOJ_03628 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IIPAIDOJ_03629 1.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IIPAIDOJ_03630 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IIPAIDOJ_03631 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IIPAIDOJ_03632 1.3e-232 purD 6.3.4.13 F Belongs to the GARS family
IIPAIDOJ_03633 3.3e-71 K helix_turn_helix ASNC type
IIPAIDOJ_03634 4.1e-226 yjeH E Amino acid permease
IIPAIDOJ_03635 6e-27 S Protein of unknown function (DUF2892)
IIPAIDOJ_03636 0.0 yerA 3.5.4.2 F adenine deaminase
IIPAIDOJ_03637 2.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
IIPAIDOJ_03638 4.8e-51 yerC S protein conserved in bacteria
IIPAIDOJ_03639 5.7e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
IIPAIDOJ_03641 1.9e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IIPAIDOJ_03642 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IIPAIDOJ_03643 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IIPAIDOJ_03644 7e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
IIPAIDOJ_03645 1e-195 yerI S homoserine kinase type II (protein kinase fold)
IIPAIDOJ_03646 1.6e-123 sapB S MgtC SapB transporter
IIPAIDOJ_03647 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IIPAIDOJ_03648 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIPAIDOJ_03649 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IIPAIDOJ_03650 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIPAIDOJ_03651 8.7e-148 yerO K Transcriptional regulator
IIPAIDOJ_03652 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IIPAIDOJ_03653 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IIPAIDOJ_03654 1.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIPAIDOJ_03655 3.9e-09
IIPAIDOJ_03656 7.8e-100
IIPAIDOJ_03658 5.3e-100 S response regulator aspartate phosphatase
IIPAIDOJ_03660 3.5e-27
IIPAIDOJ_03661 1.2e-167 yobL S Bacterial EndoU nuclease
IIPAIDOJ_03662 1.8e-176 3.4.24.40 CO amine dehydrogenase activity
IIPAIDOJ_03663 5.2e-39
IIPAIDOJ_03664 1.2e-118 S Tetratricopeptide repeat
IIPAIDOJ_03665 2e-73 S Tetratricopeptide repeat
IIPAIDOJ_03667 9.4e-127 yeeN K transcriptional regulatory protein
IIPAIDOJ_03669 9.4e-101 dhaR3 K Transcriptional regulator
IIPAIDOJ_03670 1.8e-80 yesE S SnoaL-like domain
IIPAIDOJ_03671 3.8e-143 yesF GM NAD(P)H-binding
IIPAIDOJ_03672 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
IIPAIDOJ_03673 1.5e-45 cotJB S CotJB protein
IIPAIDOJ_03674 5.2e-104 cotJC P Spore Coat
IIPAIDOJ_03675 1.3e-101 yesJ K Acetyltransferase (GNAT) family
IIPAIDOJ_03677 2.2e-100 yesL S Protein of unknown function, DUF624
IIPAIDOJ_03678 0.0 yesM 2.7.13.3 T Histidine kinase
IIPAIDOJ_03679 1.6e-202 yesN K helix_turn_helix, arabinose operon control protein
IIPAIDOJ_03680 1.4e-245 yesO G Bacterial extracellular solute-binding protein
IIPAIDOJ_03681 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
IIPAIDOJ_03682 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
IIPAIDOJ_03683 3.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
IIPAIDOJ_03684 0.0 yesS K Transcriptional regulator
IIPAIDOJ_03685 6.1e-131 E GDSL-like Lipase/Acylhydrolase
IIPAIDOJ_03686 3.2e-129 yesU S Domain of unknown function (DUF1961)
IIPAIDOJ_03687 1.4e-113 yesV S Protein of unknown function, DUF624
IIPAIDOJ_03688 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
IIPAIDOJ_03689 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
IIPAIDOJ_03690 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
IIPAIDOJ_03691 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
IIPAIDOJ_03692 0.0 yetA
IIPAIDOJ_03693 5.8e-288 lplA G Bacterial extracellular solute-binding protein
IIPAIDOJ_03694 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
IIPAIDOJ_03695 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
IIPAIDOJ_03696 3.5e-230 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IIPAIDOJ_03697 3e-122 yetF S membrane
IIPAIDOJ_03698 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IIPAIDOJ_03699 5.7e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIPAIDOJ_03700 2.4e-34
IIPAIDOJ_03701 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IIPAIDOJ_03702 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
IIPAIDOJ_03703 4.5e-104 yetJ S Belongs to the BI1 family
IIPAIDOJ_03704 2.6e-153 yetK EG EamA-like transporter family
IIPAIDOJ_03705 1.8e-87 yetL K helix_turn_helix multiple antibiotic resistance protein
IIPAIDOJ_03706 5.7e-208 yetM CH FAD binding domain
IIPAIDOJ_03708 2.3e-193 yetN S Protein of unknown function (DUF3900)
IIPAIDOJ_03709 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IIPAIDOJ_03710 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IIPAIDOJ_03711 7.4e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
IIPAIDOJ_03712 3.2e-172 yfnG 4.2.1.45 M dehydratase
IIPAIDOJ_03713 5.1e-178 yfnF M Nucleotide-diphospho-sugar transferase
IIPAIDOJ_03714 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
IIPAIDOJ_03715 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
IIPAIDOJ_03716 1.5e-204 fsr P COG0477 Permeases of the major facilitator superfamily
IIPAIDOJ_03717 8.1e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IIPAIDOJ_03718 6.4e-241 yfnA E amino acid
IIPAIDOJ_03719 1.8e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IIPAIDOJ_03720 1.1e-113 yfmS NT chemotaxis protein
IIPAIDOJ_03721 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IIPAIDOJ_03722 1.3e-73 yfmQ S Uncharacterised protein from bacillus cereus group
IIPAIDOJ_03723 1.4e-69 yfmP K transcriptional
IIPAIDOJ_03724 6.2e-208 yfmO EGP Major facilitator Superfamily
IIPAIDOJ_03725 1.6e-59 isp O Subtilase family
IIPAIDOJ_03726 6.4e-19
IIPAIDOJ_03728 6.3e-57
IIPAIDOJ_03729 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IIPAIDOJ_03730 4.5e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
IIPAIDOJ_03731 6.8e-75 yfmK 2.3.1.128 K acetyltransferase
IIPAIDOJ_03732 1.7e-185 yfmJ S N-terminal domain of oxidoreductase
IIPAIDOJ_03733 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
IIPAIDOJ_03734 2.4e-168 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_03735 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_03736 4.2e-167 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IIPAIDOJ_03737 2.9e-24 S Protein of unknown function (DUF3212)
IIPAIDOJ_03738 1.3e-57 yflT S Heat induced stress protein YflT
IIPAIDOJ_03739 1.4e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
IIPAIDOJ_03740 7.1e-235 yflS P Sodium:sulfate symporter transmembrane region
IIPAIDOJ_03741 3.7e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IIPAIDOJ_03742 2.2e-117 citT T response regulator
IIPAIDOJ_03743 1.7e-179 yflP S Tripartite tricarboxylate transporter family receptor
IIPAIDOJ_03744 2.5e-226 citM C Citrate transporter
IIPAIDOJ_03745 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
IIPAIDOJ_03746 1.5e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IIPAIDOJ_03747 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IIPAIDOJ_03748 1.3e-122 yflK S protein conserved in bacteria
IIPAIDOJ_03749 4e-18 yflJ S Protein of unknown function (DUF2639)
IIPAIDOJ_03750 4.1e-19 yflI
IIPAIDOJ_03751 2.4e-50 yflH S Protein of unknown function (DUF3243)
IIPAIDOJ_03752 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
IIPAIDOJ_03753 3.3e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IIPAIDOJ_03754 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IIPAIDOJ_03755 6e-67 yhdN S Domain of unknown function (DUF1992)
IIPAIDOJ_03756 2.2e-252 agcS_1 E Sodium alanine symporter
IIPAIDOJ_03757 2.2e-25 yfkQ EG Spore germination protein
IIPAIDOJ_03758 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IIPAIDOJ_03759 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IIPAIDOJ_03760 1.1e-132 treR K transcriptional
IIPAIDOJ_03761 1.1e-124 yfkO C nitroreductase
IIPAIDOJ_03762 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IIPAIDOJ_03763 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
IIPAIDOJ_03764 1.3e-205 ydiM EGP Major facilitator Superfamily
IIPAIDOJ_03765 1.3e-28 yfkK S Belongs to the UPF0435 family
IIPAIDOJ_03766 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIPAIDOJ_03767 3.2e-50 yfkI S gas vesicle protein
IIPAIDOJ_03768 1.3e-143 yihY S Belongs to the UPF0761 family
IIPAIDOJ_03769 3.8e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
IIPAIDOJ_03770 6.1e-183 cax P COG0387 Ca2 H antiporter
IIPAIDOJ_03771 1.2e-146 yfkD S YfkD-like protein
IIPAIDOJ_03772 6e-149 yfkC M Mechanosensitive ion channel
IIPAIDOJ_03773 5.4e-222 yfkA S YfkB-like domain
IIPAIDOJ_03774 3.2e-26 yfjT
IIPAIDOJ_03775 1.7e-153 pdaA G deacetylase
IIPAIDOJ_03776 7.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IIPAIDOJ_03777 1.7e-184 corA P Mediates influx of magnesium ions
IIPAIDOJ_03778 7.2e-166 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IIPAIDOJ_03779 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIPAIDOJ_03780 5.7e-43 S YfzA-like protein
IIPAIDOJ_03781 8.1e-190 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIPAIDOJ_03782 9.6e-85 yfjM S Psort location Cytoplasmic, score
IIPAIDOJ_03783 1.7e-29 yfjL
IIPAIDOJ_03784 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IIPAIDOJ_03785 4.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IIPAIDOJ_03786 4.6e-195 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIPAIDOJ_03787 7.8e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IIPAIDOJ_03788 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
IIPAIDOJ_03789 1.2e-25 sspH S Belongs to the SspH family
IIPAIDOJ_03790 1.2e-55 yfjF S UPF0060 membrane protein
IIPAIDOJ_03791 1.4e-85 S Family of unknown function (DUF5381)
IIPAIDOJ_03792 1.2e-124 yfjC
IIPAIDOJ_03793 9.6e-172 yfjB
IIPAIDOJ_03794 2.6e-44 yfjA S Belongs to the WXG100 family
IIPAIDOJ_03795 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IIPAIDOJ_03796 2.7e-140 glvR K Helix-turn-helix domain, rpiR family
IIPAIDOJ_03797 2.3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IIPAIDOJ_03798 0.0 yobO M COG5434 Endopolygalacturonase
IIPAIDOJ_03799 2.4e-306 yfiB3 V ABC transporter
IIPAIDOJ_03800 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
IIPAIDOJ_03801 9.8e-65 mhqP S DoxX
IIPAIDOJ_03802 9.7e-163 yfiE 1.13.11.2 S glyoxalase
IIPAIDOJ_03803 7.9e-166 K AraC-like ligand binding domain
IIPAIDOJ_03804 1.9e-08 iolT EGP Major facilitator Superfamily
IIPAIDOJ_03805 1.4e-178 G Xylose isomerase
IIPAIDOJ_03806 3.7e-229 S Oxidoreductase
IIPAIDOJ_03807 4.5e-190 yxjM T Histidine kinase
IIPAIDOJ_03808 1.6e-112 KT LuxR family transcriptional regulator
IIPAIDOJ_03809 1.4e-167 V ABC transporter, ATP-binding protein
IIPAIDOJ_03810 1.5e-206 V ABC-2 family transporter protein
IIPAIDOJ_03811 4.9e-202 V COG0842 ABC-type multidrug transport system, permease component
IIPAIDOJ_03812 4.5e-97 padR K transcriptional
IIPAIDOJ_03813 3.8e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
IIPAIDOJ_03814 1.7e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IIPAIDOJ_03815 2.4e-107 yfiR K Transcriptional regulator
IIPAIDOJ_03816 2.7e-198 yfiS EGP Major facilitator Superfamily
IIPAIDOJ_03817 8.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
IIPAIDOJ_03818 4.9e-282 yfiU EGP Major facilitator Superfamily
IIPAIDOJ_03819 4.9e-79 yfiV K transcriptional
IIPAIDOJ_03820 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIPAIDOJ_03821 5.7e-175 yfiY P ABC transporter substrate-binding protein
IIPAIDOJ_03822 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_03823 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IIPAIDOJ_03824 1.1e-166 yfhB 5.3.3.17 S PhzF family
IIPAIDOJ_03825 3.9e-107 yfhC C nitroreductase
IIPAIDOJ_03826 4e-24 yfhD S YfhD-like protein
IIPAIDOJ_03828 3.2e-172 yfhF S nucleoside-diphosphate sugar epimerase
IIPAIDOJ_03829 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
IIPAIDOJ_03830 9.7e-52 yfhH S Protein of unknown function (DUF1811)
IIPAIDOJ_03832 5.6e-209 yfhI EGP Major facilitator Superfamily
IIPAIDOJ_03833 6.2e-20 sspK S reproduction
IIPAIDOJ_03834 1.3e-44 yfhJ S WVELL protein
IIPAIDOJ_03835 2.3e-90 batE T Bacterial SH3 domain homologues
IIPAIDOJ_03836 1e-47 yfhL S SdpI/YhfL protein family
IIPAIDOJ_03837 1.3e-170 yfhM S Alpha beta hydrolase
IIPAIDOJ_03838 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IIPAIDOJ_03839 0.0 yfhO S Bacterial membrane protein YfhO
IIPAIDOJ_03840 1.2e-185 yfhP S membrane-bound metal-dependent
IIPAIDOJ_03841 4.3e-210 mutY L A G-specific
IIPAIDOJ_03842 6.9e-36 yfhS
IIPAIDOJ_03843 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IIPAIDOJ_03844 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
IIPAIDOJ_03845 1.5e-37 ygaB S YgaB-like protein
IIPAIDOJ_03846 1.3e-104 ygaC J Belongs to the UPF0374 family
IIPAIDOJ_03847 1.8e-301 ygaD V ABC transporter
IIPAIDOJ_03848 3.3e-179 ygaE S Membrane
IIPAIDOJ_03849 3.4e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IIPAIDOJ_03850 1.4e-86 bcp 1.11.1.15 O Peroxiredoxin
IIPAIDOJ_03851 4e-80 perR P Belongs to the Fur family
IIPAIDOJ_03852 9.5e-56 ygzB S UPF0295 protein
IIPAIDOJ_03853 6.7e-167 ygxA S Nucleotidyltransferase-like
IIPAIDOJ_03854 2.9e-76 ctsR K Belongs to the CtsR family
IIPAIDOJ_03855 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
IIPAIDOJ_03856 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IIPAIDOJ_03857 0.0 clpC O Belongs to the ClpA ClpB family
IIPAIDOJ_03858 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IIPAIDOJ_03859 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IIPAIDOJ_03860 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
IIPAIDOJ_03861 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IIPAIDOJ_03862 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IIPAIDOJ_03863 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IIPAIDOJ_03864 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
IIPAIDOJ_03865 1.6e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IIPAIDOJ_03866 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IIPAIDOJ_03867 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIPAIDOJ_03868 1.2e-88 yacP S RNA-binding protein containing a PIN domain
IIPAIDOJ_03869 4.4e-115 sigH K Belongs to the sigma-70 factor family
IIPAIDOJ_03870 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IIPAIDOJ_03871 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
IIPAIDOJ_03872 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IIPAIDOJ_03873 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IIPAIDOJ_03874 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IIPAIDOJ_03875 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IIPAIDOJ_03876 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
IIPAIDOJ_03877 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIPAIDOJ_03878 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIPAIDOJ_03879 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
IIPAIDOJ_03880 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IIPAIDOJ_03881 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IIPAIDOJ_03882 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IIPAIDOJ_03883 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IIPAIDOJ_03884 4.5e-185 ybaC 3.4.11.5 S Alpha/beta hydrolase family
IIPAIDOJ_03885 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IIPAIDOJ_03886 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IIPAIDOJ_03887 3e-105 rplD J Forms part of the polypeptide exit tunnel
IIPAIDOJ_03888 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IIPAIDOJ_03889 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IIPAIDOJ_03890 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IIPAIDOJ_03891 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IIPAIDOJ_03892 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IIPAIDOJ_03893 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IIPAIDOJ_03894 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IIPAIDOJ_03895 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IIPAIDOJ_03896 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IIPAIDOJ_03897 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IIPAIDOJ_03898 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IIPAIDOJ_03899 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIPAIDOJ_03900 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IIPAIDOJ_03901 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IIPAIDOJ_03902 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IIPAIDOJ_03903 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IIPAIDOJ_03904 1.9e-23 rpmD J Ribosomal protein L30
IIPAIDOJ_03905 1.8e-72 rplO J binds to the 23S rRNA
IIPAIDOJ_03906 5.5e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IIPAIDOJ_03907 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IIPAIDOJ_03908 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
IIPAIDOJ_03909 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IIPAIDOJ_03910 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IIPAIDOJ_03911 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IIPAIDOJ_03912 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IIPAIDOJ_03913 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIPAIDOJ_03914 3.6e-58 rplQ J Ribosomal protein L17
IIPAIDOJ_03915 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIPAIDOJ_03916 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIPAIDOJ_03917 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIPAIDOJ_03918 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IIPAIDOJ_03919 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IIPAIDOJ_03920 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
IIPAIDOJ_03921 2e-143 ybaJ Q Methyltransferase domain
IIPAIDOJ_03922 9.7e-66 ybaK S Protein of unknown function (DUF2521)
IIPAIDOJ_03923 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IIPAIDOJ_03924 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IIPAIDOJ_03925 1.2e-84 gerD
IIPAIDOJ_03926 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
IIPAIDOJ_03927 4.6e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
IIPAIDOJ_03928 3.4e-31 csfB S Inhibitor of sigma-G Gin
IIPAIDOJ_03929 5.8e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IIPAIDOJ_03930 9.9e-203 yaaN P Belongs to the TelA family
IIPAIDOJ_03931 6e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
IIPAIDOJ_03932 2.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IIPAIDOJ_03933 2.2e-54 yaaQ S protein conserved in bacteria
IIPAIDOJ_03934 1.5e-71 yaaR S protein conserved in bacteria
IIPAIDOJ_03935 1.1e-181 holB 2.7.7.7 L DNA polymerase III
IIPAIDOJ_03936 6.1e-146 yaaT S stage 0 sporulation protein
IIPAIDOJ_03937 4.8e-31 yabA L Involved in initiation control of chromosome replication
IIPAIDOJ_03938 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
IIPAIDOJ_03939 1.5e-49 yazA L endonuclease containing a URI domain
IIPAIDOJ_03940 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IIPAIDOJ_03941 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
IIPAIDOJ_03942 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IIPAIDOJ_03943 7.6e-143 tatD L hydrolase, TatD
IIPAIDOJ_03944 2e-167 rpfB GH23 T protein conserved in bacteria
IIPAIDOJ_03945 1.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IIPAIDOJ_03946 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IIPAIDOJ_03947 4.7e-136 yabG S peptidase
IIPAIDOJ_03948 7.8e-39 veg S protein conserved in bacteria
IIPAIDOJ_03949 8.3e-27 sspF S DNA topological change
IIPAIDOJ_03950 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IIPAIDOJ_03951 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IIPAIDOJ_03952 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
IIPAIDOJ_03953 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IIPAIDOJ_03954 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IIPAIDOJ_03955 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIPAIDOJ_03956 8.7e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IIPAIDOJ_03957 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IIPAIDOJ_03958 2.4e-39 yabK S Peptide ABC transporter permease
IIPAIDOJ_03959 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IIPAIDOJ_03960 1.5e-92 spoVT K stage V sporulation protein
IIPAIDOJ_03961 1.9e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IIPAIDOJ_03962 2.8e-242 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IIPAIDOJ_03963 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IIPAIDOJ_03964 1.5e-49 yabP S Sporulation protein YabP
IIPAIDOJ_03965 4.3e-107 yabQ S spore cortex biosynthesis protein
IIPAIDOJ_03966 1.1e-44 divIC D Septum formation initiator
IIPAIDOJ_03967 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
IIPAIDOJ_03970 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
IIPAIDOJ_03971 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
IIPAIDOJ_03972 7.4e-186 KLT serine threonine protein kinase
IIPAIDOJ_03973 1.9e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IIPAIDOJ_03974 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IIPAIDOJ_03975 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IIPAIDOJ_03976 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IIPAIDOJ_03977 6.4e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IIPAIDOJ_03978 1e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
IIPAIDOJ_03979 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IIPAIDOJ_03980 1.4e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IIPAIDOJ_03981 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
IIPAIDOJ_03982 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
IIPAIDOJ_03983 1.7e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IIPAIDOJ_03984 1e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IIPAIDOJ_03985 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IIPAIDOJ_03986 4.1e-30 yazB K transcriptional
IIPAIDOJ_03987 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIPAIDOJ_03988 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IIPAIDOJ_03989 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
IIPAIDOJ_03990 7.9e-32 yaaL S Protein of unknown function (DUF2508)
IIPAIDOJ_03991 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IIPAIDOJ_03992 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IIPAIDOJ_03993 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIPAIDOJ_03994 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IIPAIDOJ_03995 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
IIPAIDOJ_03996 1.2e-212 yaaH M Glycoside Hydrolase Family
IIPAIDOJ_03997 1e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
IIPAIDOJ_03998 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
IIPAIDOJ_03999 1.3e-09
IIPAIDOJ_04000 3.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IIPAIDOJ_04001 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IIPAIDOJ_04002 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IIPAIDOJ_04003 8.9e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IIPAIDOJ_04004 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IIPAIDOJ_04005 3.7e-179 yaaC S YaaC-like Protein
IIPAIDOJ_04006 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPAIDOJ_04007 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)