ORF_ID e_value Gene_name EC_number CAZy COGs Description
KEFONFAP_00001 6.4e-31 L PFAM Integrase catalytic
KEFONFAP_00002 1.8e-16 L Helix-turn-helix domain
KEFONFAP_00003 1.2e-247 S Psort location CytoplasmicMembrane, score 9.99
KEFONFAP_00004 1.1e-69
KEFONFAP_00005 7.6e-237 wcoI DM Psort location CytoplasmicMembrane, score
KEFONFAP_00006 5.1e-129
KEFONFAP_00007 5e-171 S G5
KEFONFAP_00008 3.3e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
KEFONFAP_00009 9.3e-121 F Domain of unknown function (DUF4916)
KEFONFAP_00010 1.3e-159 mhpC I Alpha/beta hydrolase family
KEFONFAP_00011 1.3e-211 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
KEFONFAP_00012 1.7e-69 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
KEFONFAP_00013 1.6e-224 S Uncharacterized conserved protein (DUF2183)
KEFONFAP_00014 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
KEFONFAP_00015 2.7e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KEFONFAP_00016 4e-212 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
KEFONFAP_00017 1.4e-130 glxR K helix_turn_helix, cAMP Regulatory protein
KEFONFAP_00018 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
KEFONFAP_00019 1.8e-229 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
KEFONFAP_00020 1.8e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
KEFONFAP_00021 6.3e-123 glpR K DeoR C terminal sensor domain
KEFONFAP_00022 6.6e-253 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
KEFONFAP_00023 1.3e-232 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
KEFONFAP_00024 1.4e-15 lmrB EGP Major facilitator Superfamily
KEFONFAP_00025 6.4e-44 gcvR T Belongs to the UPF0237 family
KEFONFAP_00026 3.2e-253 S UPF0210 protein
KEFONFAP_00027 7.6e-115 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KEFONFAP_00028 9.2e-186 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
KEFONFAP_00029 5.3e-125
KEFONFAP_00030 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEFONFAP_00031 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEFONFAP_00032 0.0 E Transglutaminase-like superfamily
KEFONFAP_00033 1.1e-237 S Protein of unknown function DUF58
KEFONFAP_00034 0.0 S Fibronectin type 3 domain
KEFONFAP_00035 1.2e-221 KLT Protein tyrosine kinase
KEFONFAP_00036 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
KEFONFAP_00037 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
KEFONFAP_00038 6.1e-233 G Major Facilitator Superfamily
KEFONFAP_00039 7.1e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KEFONFAP_00040 1.7e-165 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KEFONFAP_00041 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KEFONFAP_00042 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
KEFONFAP_00043 8.9e-259 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KEFONFAP_00044 1.1e-121 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KEFONFAP_00045 8.5e-268 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
KEFONFAP_00046 1e-204 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KEFONFAP_00047 4.8e-192 ftsE D Cell division ATP-binding protein FtsE
KEFONFAP_00048 9.8e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
KEFONFAP_00049 3.2e-144 usp 3.5.1.28 CBM50 D CHAP domain protein
KEFONFAP_00050 9.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KEFONFAP_00051 1.6e-142 pknD ET ABC transporter, substrate-binding protein, family 3
KEFONFAP_00052 5.8e-169 pknD ET ABC transporter, substrate-binding protein, family 3
KEFONFAP_00053 8e-153 yecS E Binding-protein-dependent transport system inner membrane component
KEFONFAP_00054 1.4e-150 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
KEFONFAP_00055 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KEFONFAP_00056 5.3e-158 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
KEFONFAP_00057 4.8e-182 K Periplasmic binding protein domain
KEFONFAP_00058 2.1e-145 K Psort location Cytoplasmic, score
KEFONFAP_00059 7e-110 nusG K Participates in transcription elongation, termination and antitermination
KEFONFAP_00060 1.4e-31 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KEFONFAP_00062 3.8e-229 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
KEFONFAP_00063 1.5e-215 G polysaccharide deacetylase
KEFONFAP_00064 1.9e-195 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KEFONFAP_00065 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KEFONFAP_00066 5.8e-39 rpmA J Ribosomal L27 protein
KEFONFAP_00067 1.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
KEFONFAP_00068 0.0 rne 3.1.26.12 J Ribonuclease E/G family
KEFONFAP_00069 2.4e-231 dapE 3.5.1.18 E Peptidase dimerisation domain
KEFONFAP_00070 1.9e-167 mdcF S Transporter, auxin efflux carrier (AEC) family protein
KEFONFAP_00071 1.7e-165 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
KEFONFAP_00072 3.2e-149 S Amidohydrolase
KEFONFAP_00073 5.4e-202 fucP G Major Facilitator Superfamily
KEFONFAP_00074 2.8e-148 IQ KR domain
KEFONFAP_00075 2.7e-249 4.2.1.68 M Enolase C-terminal domain-like
KEFONFAP_00076 1.2e-191 K Bacterial regulatory proteins, lacI family
KEFONFAP_00077 2e-221 V Efflux ABC transporter, permease protein
KEFONFAP_00078 3.6e-130 V ATPases associated with a variety of cellular activities
KEFONFAP_00079 7.2e-29 S Protein of unknown function (DUF1778)
KEFONFAP_00080 3.2e-89 K Acetyltransferase (GNAT) family
KEFONFAP_00081 9e-270 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
KEFONFAP_00082 1.4e-185 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KEFONFAP_00083 1.8e-237 hom 1.1.1.3 E Homoserine dehydrogenase
KEFONFAP_00084 3.8e-231 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
KEFONFAP_00085 2.5e-57 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KEFONFAP_00086 1.5e-302 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KEFONFAP_00087 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KEFONFAP_00088 8.1e-131 K Bacterial regulatory proteins, tetR family
KEFONFAP_00089 2.1e-222 G Transmembrane secretion effector
KEFONFAP_00090 6.8e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KEFONFAP_00091 7.6e-255 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
KEFONFAP_00092 2.1e-157 ET Bacterial periplasmic substrate-binding proteins
KEFONFAP_00093 1.1e-119 ytmL P Binding-protein-dependent transport system inner membrane component
KEFONFAP_00094 2.6e-138 P Binding-protein-dependent transport system inner membrane component
KEFONFAP_00095 9.5e-103 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
KEFONFAP_00096 4.5e-132 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
KEFONFAP_00097 9e-220 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
KEFONFAP_00098 4.3e-40 2.7.13.3 T Histidine kinase
KEFONFAP_00099 2.5e-19 S Bacterial PH domain
KEFONFAP_00100 9.3e-132 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KEFONFAP_00101 4.2e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KEFONFAP_00102 2.2e-140 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
KEFONFAP_00103 2.8e-257 S Calcineurin-like phosphoesterase
KEFONFAP_00104 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KEFONFAP_00105 2.3e-233 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
KEFONFAP_00106 4.7e-130
KEFONFAP_00107 0.0 G N-terminal domain of (some) glycogen debranching enzymes
KEFONFAP_00108 1.6e-49 P Binding-protein-dependent transport system inner membrane component
KEFONFAP_00109 3.9e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KEFONFAP_00110 2.8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KEFONFAP_00111 3.7e-215 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KEFONFAP_00112 2e-216 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEFONFAP_00114 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KEFONFAP_00115 1.2e-163 S Auxin Efflux Carrier
KEFONFAP_00116 4e-158 fahA Q Fumarylacetoacetate (FAA) hydrolase family
KEFONFAP_00117 9.2e-106 S Domain of unknown function (DUF4190)
KEFONFAP_00118 5.1e-162
KEFONFAP_00119 7.8e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
KEFONFAP_00120 8.2e-64 K Helix-turn-helix domain
KEFONFAP_00122 5.9e-47 5.3.1.27 G sugar phosphate isomerase involved in capsule formation
KEFONFAP_00123 1.9e-57 G Branched-chain amino acid transport system / permease component
KEFONFAP_00124 1.9e-72 P branched-chain amino acid ABC transporter, permease protein
KEFONFAP_00125 1.1e-119 G ATPases associated with a variety of cellular activities
KEFONFAP_00126 2.1e-79 G ABC-type sugar transport system periplasmic component
KEFONFAP_00127 6.6e-167 xylB 1.1.1.57, 2.7.1.17 G Belongs to the FGGY kinase family
KEFONFAP_00128 4.7e-76 xylR GK ROK family
KEFONFAP_00129 5.5e-43
KEFONFAP_00130 8.3e-20 malC G Binding-protein-dependent transport system inner membrane component
KEFONFAP_00131 1.6e-168 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KEFONFAP_00132 0.0 gcs2 S A circularly permuted ATPgrasp
KEFONFAP_00133 7.4e-149 E Transglutaminase/protease-like homologues
KEFONFAP_00135 2.6e-101 K helix_turn _helix lactose operon repressor
KEFONFAP_00136 8.9e-125
KEFONFAP_00137 1.4e-184 nusA K Participates in both transcription termination and antitermination
KEFONFAP_00138 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KEFONFAP_00139 4e-81 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KEFONFAP_00140 5.4e-220 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KEFONFAP_00141 2.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
KEFONFAP_00142 3.6e-261 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KEFONFAP_00143 1e-97
KEFONFAP_00145 9.1e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KEFONFAP_00146 1e-172 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KEFONFAP_00147 3.3e-275 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KEFONFAP_00148 2.1e-73 K Transcriptional regulator
KEFONFAP_00149 1.5e-197 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KEFONFAP_00150 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
KEFONFAP_00151 0.0 crr 2.7.1.193 G pts system, glucose-specific IIABC component
KEFONFAP_00152 5.9e-163 arbG K CAT RNA binding domain
KEFONFAP_00153 6.5e-200 I Diacylglycerol kinase catalytic domain
KEFONFAP_00154 3.3e-242 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KEFONFAP_00156 5.5e-250 G Bacterial extracellular solute-binding protein
KEFONFAP_00157 6.9e-173 malC G Binding-protein-dependent transport system inner membrane component
KEFONFAP_00158 2.5e-167 G ABC transporter permease
KEFONFAP_00159 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
KEFONFAP_00160 6.3e-204 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
KEFONFAP_00161 4.5e-167 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KEFONFAP_00162 4.4e-118 degU K helix_turn_helix, Lux Regulon
KEFONFAP_00163 7.6e-236 tcsS3 KT PspC domain
KEFONFAP_00164 4.8e-283 pspC KT PspC domain
KEFONFAP_00165 1.9e-66
KEFONFAP_00166 0.0 S alpha beta
KEFONFAP_00167 1.4e-110 S Protein of unknown function (DUF4125)
KEFONFAP_00168 0.0 S Domain of unknown function (DUF4037)
KEFONFAP_00169 8.9e-215 araJ EGP Major facilitator Superfamily
KEFONFAP_00171 4.7e-311 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KEFONFAP_00172 1.2e-174 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KEFONFAP_00173 1.1e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KEFONFAP_00174 5.4e-116 phoU P Plays a role in the regulation of phosphate uptake
KEFONFAP_00175 6.9e-170 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KEFONFAP_00176 8.1e-33
KEFONFAP_00177 4.4e-211 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KEFONFAP_00178 1.7e-168 usp 3.5.1.28 CBM50 S CHAP domain
KEFONFAP_00179 1.4e-101 M NlpC/P60 family
KEFONFAP_00180 1.5e-103 M NlpC/P60 family
KEFONFAP_00181 1.6e-10 M NlpC/P60 family
KEFONFAP_00182 2.1e-188 T Universal stress protein family
KEFONFAP_00183 3.4e-73 attW O OsmC-like protein
KEFONFAP_00184 7.8e-168 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KEFONFAP_00185 7.3e-126 folA 1.5.1.3 H dihydrofolate reductase
KEFONFAP_00186 1.5e-97 ptpA 3.1.3.48 T low molecular weight
KEFONFAP_00187 4.1e-110 vex2 V ABC transporter, ATP-binding protein
KEFONFAP_00188 4.4e-209 vex1 V Efflux ABC transporter, permease protein
KEFONFAP_00189 5.2e-219 vex3 V ABC transporter permease
KEFONFAP_00190 3.5e-09 L HTH-like domain
KEFONFAP_00191 0.0 G Glycosyl hydrolase family 20, domain 2
KEFONFAP_00192 4.5e-219 GK ROK family
KEFONFAP_00193 1.3e-243 G Bacterial extracellular solute-binding protein
KEFONFAP_00194 6.3e-22 L Helix-turn-helix domain
KEFONFAP_00195 4.8e-185 lacR K Transcriptional regulator, LacI family
KEFONFAP_00196 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KEFONFAP_00197 7e-47 lacS G Psort location CytoplasmicMembrane, score 10.00
KEFONFAP_00198 2.6e-230 S AAA domain
KEFONFAP_00199 3.1e-204 EGP Major Facilitator Superfamily
KEFONFAP_00200 2.1e-29 L Transposase DDE domain
KEFONFAP_00201 3.8e-12 L Transposase DDE domain
KEFONFAP_00202 1.9e-105 K Bacterial regulatory proteins, tetR family
KEFONFAP_00203 4.7e-257 MA20_36090 S Psort location Cytoplasmic, score 8.87
KEFONFAP_00204 1.4e-89 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KEFONFAP_00205 1.2e-79 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KEFONFAP_00206 9.2e-72 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
KEFONFAP_00207 2.8e-112 P Sodium/hydrogen exchanger family
KEFONFAP_00209 4.9e-11
KEFONFAP_00210 1.1e-97
KEFONFAP_00211 0.0 1.3.98.1, 3.2.1.21 GH3 M Conserved repeat domain
KEFONFAP_00212 2.1e-277 M LPXTG cell wall anchor motif
KEFONFAP_00214 5.5e-86
KEFONFAP_00215 1.6e-107
KEFONFAP_00216 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KEFONFAP_00217 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KEFONFAP_00218 1.3e-89 lemA S LemA family
KEFONFAP_00219 0.0 S Predicted membrane protein (DUF2207)
KEFONFAP_00220 9.9e-12 S Predicted membrane protein (DUF2207)
KEFONFAP_00221 8.2e-59 S Predicted membrane protein (DUF2207)
KEFONFAP_00222 4.4e-58 S Predicted membrane protein (DUF2207)
KEFONFAP_00223 3.1e-20
KEFONFAP_00224 4.1e-169 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
KEFONFAP_00225 1.9e-200 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KEFONFAP_00226 6.4e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KEFONFAP_00227 1e-34 CP_0960 S Belongs to the UPF0109 family
KEFONFAP_00228 7e-62 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KEFONFAP_00229 4.2e-213 S Endonuclease/Exonuclease/phosphatase family
KEFONFAP_00230 9e-266 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KEFONFAP_00231 2.3e-162 P Cation efflux family
KEFONFAP_00232 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEFONFAP_00233 7.1e-137 guaA1 6.3.5.2 F Peptidase C26
KEFONFAP_00234 0.0 yjjK S ABC transporter
KEFONFAP_00235 7.8e-73 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
KEFONFAP_00236 3.9e-44 stbC S Plasmid stability protein
KEFONFAP_00237 1.5e-92 ilvN 2.2.1.6 E ACT domain
KEFONFAP_00238 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
KEFONFAP_00239 6.3e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KEFONFAP_00240 9.3e-21 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KEFONFAP_00241 7.6e-117 yceD S Uncharacterized ACR, COG1399
KEFONFAP_00242 6.3e-76
KEFONFAP_00243 4.3e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KEFONFAP_00244 1.4e-47 S Protein of unknown function (DUF3039)
KEFONFAP_00245 1.9e-197 yghZ C Aldo/keto reductase family
KEFONFAP_00246 6.3e-78 soxR K MerR, DNA binding
KEFONFAP_00247 4.5e-117
KEFONFAP_00248 1.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KEFONFAP_00249 7e-144 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KEFONFAP_00250 6.6e-126 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KEFONFAP_00251 2.4e-176 S Auxin Efflux Carrier
KEFONFAP_00254 0.0 pgi 5.3.1.9 G Belongs to the GPI family
KEFONFAP_00255 5.3e-259 abcT3 P ATPases associated with a variety of cellular activities
KEFONFAP_00256 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
KEFONFAP_00257 1.5e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KEFONFAP_00258 7.2e-164 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KEFONFAP_00259 1e-159 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KEFONFAP_00260 3.6e-210 K helix_turn _helix lactose operon repressor
KEFONFAP_00261 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KEFONFAP_00262 3.6e-55 araE EGP Major facilitator Superfamily
KEFONFAP_00265 0.0 cydD V ABC transporter transmembrane region
KEFONFAP_00266 5.2e-38 EGP Major facilitator Superfamily
KEFONFAP_00267 7.1e-261 G Bacterial extracellular solute-binding protein
KEFONFAP_00268 3.5e-10 L Transposase DDE domain
KEFONFAP_00269 1.6e-271 aspA 4.3.1.1 E Fumarase C C-terminus
KEFONFAP_00270 1.2e-135 M Mechanosensitive ion channel
KEFONFAP_00271 3.7e-185 S CAAX protease self-immunity
KEFONFAP_00272 9.7e-239 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KEFONFAP_00273 6.9e-151 U Binding-protein-dependent transport system inner membrane component
KEFONFAP_00274 9.9e-161 U Binding-protein-dependent transport system inner membrane component
KEFONFAP_00275 2.9e-218 P Bacterial extracellular solute-binding protein
KEFONFAP_00276 9.1e-228 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KEFONFAP_00277 4.6e-180 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
KEFONFAP_00278 8.8e-189 plsC2 2.3.1.51 I Phosphate acyltransferases
KEFONFAP_00279 3.6e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
KEFONFAP_00282 6.9e-118 cyaA 4.6.1.1 S CYTH
KEFONFAP_00283 1.1e-170 trxA2 O Tetratricopeptide repeat
KEFONFAP_00284 2.5e-178
KEFONFAP_00285 6.1e-179
KEFONFAP_00286 3.6e-158 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
KEFONFAP_00287 5.2e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KEFONFAP_00288 9.4e-49 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KEFONFAP_00289 6.1e-282 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KEFONFAP_00290 6.1e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KEFONFAP_00291 1.3e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KEFONFAP_00292 3.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KEFONFAP_00293 1.8e-58 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KEFONFAP_00294 1.7e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KEFONFAP_00295 1.9e-144 atpB C it plays a direct role in the translocation of protons across the membrane
KEFONFAP_00296 2.3e-206 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KEFONFAP_00298 0.0 K RNA polymerase II activating transcription factor binding
KEFONFAP_00299 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
KEFONFAP_00300 2.8e-90 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KEFONFAP_00301 1.1e-96 mntP P Probably functions as a manganese efflux pump
KEFONFAP_00302 1.1e-116
KEFONFAP_00303 4e-139 KT Transcriptional regulatory protein, C terminal
KEFONFAP_00304 5.7e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KEFONFAP_00305 2.7e-280 E Bacterial extracellular solute-binding proteins, family 5 Middle
KEFONFAP_00306 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KEFONFAP_00307 0.0 S domain protein
KEFONFAP_00308 1e-63 tyrA 5.4.99.5 E Chorismate mutase type II
KEFONFAP_00309 5.4e-50 pabC 2.6.1.42, 4.1.3.38 EH Amino-transferase class IV
KEFONFAP_00310 1.6e-35 L Helix-turn-helix domain
KEFONFAP_00311 3.2e-131 rafA 3.2.1.22 G alpha-galactosidase
KEFONFAP_00312 2.2e-114 araQ U Binding-protein-dependent transport system inner membrane component
KEFONFAP_00313 1.2e-120 lacF P Binding-protein-dependent transport system inner membrane component
KEFONFAP_00314 2.8e-153 araN G Bacterial extracellular solute-binding protein
KEFONFAP_00315 5.1e-50 K helix_turn_helix, arabinose operon control protein
KEFONFAP_00316 5.5e-116 L Transposase
KEFONFAP_00317 1.3e-46 pabC 2.6.1.42, 4.1.3.38 EH Amino-transferase class IV
KEFONFAP_00318 3.3e-291 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KEFONFAP_00319 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
KEFONFAP_00320 3.3e-52 S Protein of unknown function (DUF2469)
KEFONFAP_00321 4e-195 2.3.1.57 J Acetyltransferase (GNAT) domain
KEFONFAP_00322 5.6e-283 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KEFONFAP_00323 4.6e-288 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KEFONFAP_00324 4.1e-51 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KEFONFAP_00325 3.3e-160 K Psort location Cytoplasmic, score
KEFONFAP_00326 4.5e-178
KEFONFAP_00327 5.4e-167 V ABC transporter
KEFONFAP_00328 6.2e-155 spoU 2.1.1.185 J RNA methyltransferase TrmH family
KEFONFAP_00329 1.6e-109 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KEFONFAP_00330 1.6e-210 rmuC S RmuC family
KEFONFAP_00331 9.6e-43 csoR S Metal-sensitive transcriptional repressor
KEFONFAP_00332 0.0 pacS 1.9.3.1, 3.6.3.54 P E1-E2 ATPase
KEFONFAP_00333 4e-117 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KEFONFAP_00335 2.7e-71 rplI J Binds to the 23S rRNA
KEFONFAP_00336 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KEFONFAP_00337 6.8e-76 ssb1 L Single-stranded DNA-binding protein
KEFONFAP_00338 4.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KEFONFAP_00339 5.2e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KEFONFAP_00340 6.9e-192 V Acetyltransferase (GNAT) domain
KEFONFAP_00341 1.1e-44 V Acetyltransferase (GNAT) domain
KEFONFAP_00342 0.0 smc D Required for chromosome condensation and partitioning
KEFONFAP_00343 3.4e-302 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
KEFONFAP_00344 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
KEFONFAP_00345 3.1e-95 3.6.1.55 F NUDIX domain
KEFONFAP_00346 6.1e-246 nagA 3.5.1.25 G Amidohydrolase family
KEFONFAP_00347 1.8e-150 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KEFONFAP_00348 1.5e-208 GK ROK family
KEFONFAP_00349 2.2e-165 2.7.1.2 GK ROK family
KEFONFAP_00351 5e-221 GK ROK family
KEFONFAP_00352 2.3e-167 2.7.1.4 G pfkB family carbohydrate kinase
KEFONFAP_00353 9.5e-44 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KEFONFAP_00354 7e-15
KEFONFAP_00355 8.1e-172 ftsQ 6.3.2.4 D Cell division protein FtsQ
KEFONFAP_00356 7.5e-283 murC 6.3.2.8 M Belongs to the MurCDEF family
KEFONFAP_00357 1.1e-217 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KEFONFAP_00358 1.5e-225 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
KEFONFAP_00359 4.3e-272 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KEFONFAP_00360 1.7e-204 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KEFONFAP_00361 2e-240 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KEFONFAP_00362 2.6e-155 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KEFONFAP_00363 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
KEFONFAP_00364 1.3e-65 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KEFONFAP_00365 1.8e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KEFONFAP_00366 1.3e-93 mraZ K Belongs to the MraZ family
KEFONFAP_00367 0.0 L DNA helicase
KEFONFAP_00368 7.5e-230 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KEFONFAP_00369 8.4e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KEFONFAP_00370 7.4e-46 M Lysin motif
KEFONFAP_00371 8.4e-128 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KEFONFAP_00372 4.1e-162 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KEFONFAP_00373 1.5e-175 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
KEFONFAP_00374 6.9e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KEFONFAP_00375 3.4e-123 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
KEFONFAP_00376 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
KEFONFAP_00377 1.9e-217 EGP Major facilitator Superfamily
KEFONFAP_00378 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
KEFONFAP_00379 1.6e-279 S Uncharacterized protein conserved in bacteria (DUF2252)
KEFONFAP_00380 8.3e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
KEFONFAP_00381 3.4e-120 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KEFONFAP_00382 2.3e-99
KEFONFAP_00383 2.7e-111 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
KEFONFAP_00384 1.8e-220 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KEFONFAP_00385 1.1e-253 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KEFONFAP_00386 1.1e-53 acyP 3.6.1.7 C Acylphosphatase
KEFONFAP_00387 2.2e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
KEFONFAP_00388 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
KEFONFAP_00389 7.7e-163 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
KEFONFAP_00390 4.1e-111 S Amidohydrolase
KEFONFAP_00391 5.8e-146 IQ KR domain
KEFONFAP_00392 6.8e-245 4.2.1.68 M Enolase C-terminal domain-like
KEFONFAP_00393 4.4e-266 G Bacterial extracellular solute-binding protein
KEFONFAP_00394 1.1e-175 P Binding-protein-dependent transport system inner membrane component
KEFONFAP_00395 1.1e-156 P Binding-protein-dependent transport system inner membrane component
KEFONFAP_00396 2.6e-85 K Bacterial regulatory proteins, lacI family
KEFONFAP_00397 8.1e-36 K Bacterial regulatory proteins, lacI family
KEFONFAP_00399 6.5e-12 S Psort location Extracellular, score 8.82
KEFONFAP_00400 5e-84 L Transposase and inactivated derivatives IS30 family
KEFONFAP_00401 1.3e-25 cysB 4.2.1.22 EGP Major facilitator Superfamily
KEFONFAP_00402 1e-42 cysB 4.2.1.22 EGP Major facilitator Superfamily
KEFONFAP_00403 1e-11
KEFONFAP_00404 1.6e-118 K Bacterial regulatory proteins, tetR family
KEFONFAP_00405 3.5e-217 G Transmembrane secretion effector
KEFONFAP_00406 5.4e-17 K addiction module antidote protein HigA
KEFONFAP_00407 6.9e-242 S HipA-like C-terminal domain
KEFONFAP_00408 1.3e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KEFONFAP_00409 7.4e-110 papP E Binding-protein-dependent transport system inner membrane component
KEFONFAP_00410 1.2e-118 E Binding-protein-dependent transport system inner membrane component
KEFONFAP_00411 1.2e-138 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
KEFONFAP_00412 4.8e-154 cjaA ET Bacterial periplasmic substrate-binding proteins
KEFONFAP_00413 1.4e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEFONFAP_00414 1.3e-287 pip 3.4.11.5 S alpha/beta hydrolase fold
KEFONFAP_00415 0.0 tcsS2 T Histidine kinase
KEFONFAP_00416 1.1e-139 K helix_turn_helix, Lux Regulon
KEFONFAP_00417 0.0 MV MacB-like periplasmic core domain
KEFONFAP_00418 1.7e-168 V ABC transporter, ATP-binding protein
KEFONFAP_00419 4.5e-252 metY 2.5.1.49 E Aminotransferase class-V
KEFONFAP_00420 2.8e-165 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KEFONFAP_00421 4.7e-23 L Transposase and inactivated derivatives IS30 family
KEFONFAP_00422 8.3e-75 yraN L Belongs to the UPF0102 family
KEFONFAP_00423 9.8e-291 comM O Magnesium chelatase, subunit ChlI C-terminal
KEFONFAP_00424 0.0 dprA 5.99.1.2 LU DNA recombination-mediator protein A
KEFONFAP_00425 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
KEFONFAP_00426 2.7e-182 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
KEFONFAP_00427 2.1e-112 safC S O-methyltransferase
KEFONFAP_00428 8.9e-167 fmt2 3.2.2.10 S Belongs to the LOG family
KEFONFAP_00429 7.4e-221 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KEFONFAP_00430 4.4e-238 patB 4.4.1.8 E Aminotransferase, class I II
KEFONFAP_00433 1.3e-249 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KEFONFAP_00434 7.3e-121 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KEFONFAP_00435 6.5e-116 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KEFONFAP_00436 3.4e-59
KEFONFAP_00437 2.4e-243 clcA_2 P Voltage gated chloride channel
KEFONFAP_00438 4.4e-234 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KEFONFAP_00439 3.4e-252 rnd 3.1.13.5 J 3'-5' exonuclease
KEFONFAP_00440 1.4e-118 S Protein of unknown function (DUF3000)
KEFONFAP_00441 8.7e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KEFONFAP_00442 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
KEFONFAP_00443 1e-37
KEFONFAP_00444 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KEFONFAP_00445 4.1e-225 S Peptidase dimerisation domain
KEFONFAP_00446 7.4e-113 metI P Binding-protein-dependent transport system inner membrane component
KEFONFAP_00447 1.4e-220 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KEFONFAP_00448 5.1e-176 metQ P NLPA lipoprotein
KEFONFAP_00449 5.6e-158 S Sucrose-6F-phosphate phosphohydrolase
KEFONFAP_00452 2.7e-134 3.1.3.85 G Phosphoglycerate mutase family
KEFONFAP_00453 6.5e-66 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KEFONFAP_00454 3e-262 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KEFONFAP_00455 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KEFONFAP_00456 1.1e-300 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KEFONFAP_00457 3.7e-16
KEFONFAP_00459 5.2e-28
KEFONFAP_00460 4.6e-70 S Putative DNA-binding domain
KEFONFAP_00461 9.1e-107 pepE 3.4.13.21 E Belongs to the peptidase S51 family
KEFONFAP_00463 0.0 4.2.1.53 S MCRA family
KEFONFAP_00464 1e-167 dkgA 1.1.1.346 C Aldo/keto reductase family
KEFONFAP_00465 5.3e-68 yneG S Domain of unknown function (DUF4186)
KEFONFAP_00466 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
KEFONFAP_00467 2.4e-200 K WYL domain
KEFONFAP_00468 9e-178 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KEFONFAP_00469 1.6e-89 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KEFONFAP_00470 4.9e-20 tccB2 V DivIVA protein
KEFONFAP_00471 4.9e-45 yggT S YGGT family
KEFONFAP_00472 6.6e-68 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KEFONFAP_00473 1.2e-211 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KEFONFAP_00474 2.8e-248 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KEFONFAP_00475 3.3e-296 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
KEFONFAP_00476 1e-157 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KEFONFAP_00477 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KEFONFAP_00478 1.6e-227 O AAA domain (Cdc48 subfamily)
KEFONFAP_00479 1e-140 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KEFONFAP_00480 4.7e-61 S Thiamine-binding protein
KEFONFAP_00481 7.1e-248 ydjK G Sugar (and other) transporter
KEFONFAP_00482 8.1e-215 2.7.13.3 T Histidine kinase
KEFONFAP_00483 6.1e-123 K helix_turn_helix, Lux Regulon
KEFONFAP_00484 1.3e-190
KEFONFAP_00485 6.6e-257 O SERine Proteinase INhibitors
KEFONFAP_00486 1.8e-195 K helix_turn _helix lactose operon repressor
KEFONFAP_00487 6.2e-241 lacY P LacY proton/sugar symporter
KEFONFAP_00488 3e-303 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
KEFONFAP_00489 3.2e-141 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
KEFONFAP_00490 2.5e-149 C Putative TM nitroreductase
KEFONFAP_00491 6.4e-198 S Glycosyltransferase, group 2 family protein
KEFONFAP_00492 1.3e-93 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KEFONFAP_00493 0.0 ecfA GP ABC transporter, ATP-binding protein
KEFONFAP_00494 3.1e-47 yhbY J CRS1_YhbY
KEFONFAP_00495 1.6e-53 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KEFONFAP_00496 6.9e-52
KEFONFAP_00497 3.8e-187 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KEFONFAP_00498 5.5e-251 EGP Major facilitator Superfamily
KEFONFAP_00499 2.1e-34 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KEFONFAP_00500 6.9e-11 KT Transcriptional regulatory protein, C terminal
KEFONFAP_00501 7.5e-250 rarA L Recombination factor protein RarA
KEFONFAP_00502 0.0 helY L DEAD DEAH box helicase
KEFONFAP_00503 1.5e-197 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
KEFONFAP_00504 3.5e-285 ydfD EK Alanine-glyoxylate amino-transferase
KEFONFAP_00505 5.1e-111 argO S LysE type translocator
KEFONFAP_00506 9.9e-291 phoN I PAP2 superfamily
KEFONFAP_00507 1.2e-194 gluD E Binding-protein-dependent transport system inner membrane component
KEFONFAP_00508 3.4e-110 gluC E Binding-protein-dependent transport system inner membrane component
KEFONFAP_00509 1.1e-144 gluB ET Belongs to the bacterial solute-binding protein 3 family
KEFONFAP_00510 7.6e-152 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
KEFONFAP_00511 5.2e-101 S Aminoacyl-tRNA editing domain
KEFONFAP_00512 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KEFONFAP_00513 4.3e-253 hisS 6.1.1.21 J Histidyl-tRNA synthetase
KEFONFAP_00514 1.2e-210 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
KEFONFAP_00515 0.0 3.1.3.5 F 5'-nucleotidase, C-terminal domain
KEFONFAP_00516 1.7e-142 3.5.2.10 S Creatinine amidohydrolase
KEFONFAP_00517 4e-251 proP EGP Sugar (and other) transporter
KEFONFAP_00519 1.4e-281 purR QT Purine catabolism regulatory protein-like family
KEFONFAP_00520 5.7e-255 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
KEFONFAP_00521 0.0 clpC O ATPase family associated with various cellular activities (AAA)
KEFONFAP_00522 5.4e-178 uspA T Belongs to the universal stress protein A family
KEFONFAP_00523 9e-179 S Protein of unknown function (DUF3027)
KEFONFAP_00524 1.7e-66 cspB K 'Cold-shock' DNA-binding domain
KEFONFAP_00525 2.6e-309 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KEFONFAP_00526 4.4e-132 KT Response regulator receiver domain protein
KEFONFAP_00527 5.1e-100
KEFONFAP_00528 4.2e-33 S Proteins of 100 residues with WXG
KEFONFAP_00529 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KEFONFAP_00530 6.1e-38 K 'Cold-shock' DNA-binding domain
KEFONFAP_00531 3.1e-84 S LytR cell envelope-related transcriptional attenuator
KEFONFAP_00532 1.9e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KEFONFAP_00533 1.4e-187 moxR S ATPase family associated with various cellular activities (AAA)
KEFONFAP_00534 1.3e-163 S Protein of unknown function DUF58
KEFONFAP_00535 2.6e-84
KEFONFAP_00536 8.8e-190 S von Willebrand factor (vWF) type A domain
KEFONFAP_00537 2.5e-152 S von Willebrand factor (vWF) type A domain
KEFONFAP_00538 3.1e-56
KEFONFAP_00539 4.4e-254 S PGAP1-like protein
KEFONFAP_00540 2.9e-111 ykoE S ABC-type cobalt transport system, permease component
KEFONFAP_00541 2.7e-277 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
KEFONFAP_00542 0.0 S Lysylphosphatidylglycerol synthase TM region
KEFONFAP_00543 8.1e-42 hup L Belongs to the bacterial histone-like protein family
KEFONFAP_00544 1.5e-283 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KEFONFAP_00546 8.9e-175 hisN 3.1.3.25 G Inositol monophosphatase family
KEFONFAP_00547 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
KEFONFAP_00548 6.1e-134 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
KEFONFAP_00549 4.8e-162 G Phosphotransferase System
KEFONFAP_00550 2.1e-46 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
KEFONFAP_00551 4e-78 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KEFONFAP_00552 2.6e-71 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KEFONFAP_00553 5.8e-280 manR K PRD domain
KEFONFAP_00554 1.8e-133 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KEFONFAP_00555 3.3e-286 arc O AAA ATPase forming ring-shaped complexes
KEFONFAP_00556 2.5e-124 apl 3.1.3.1 S SNARE associated Golgi protein
KEFONFAP_00557 1.4e-117 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
KEFONFAP_00558 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KEFONFAP_00559 4.3e-132 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KEFONFAP_00560 1.2e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KEFONFAP_00561 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
KEFONFAP_00562 4.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KEFONFAP_00563 1.1e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KEFONFAP_00564 2.5e-166 G Fic/DOC family
KEFONFAP_00565 3.4e-50 S Appr-1'-p processing enzyme
KEFONFAP_00566 7.1e-86 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KEFONFAP_00567 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
KEFONFAP_00568 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
KEFONFAP_00569 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
KEFONFAP_00570 3e-245 srrA1 G Bacterial extracellular solute-binding protein
KEFONFAP_00571 4.3e-172 malC G Binding-protein-dependent transport system inner membrane component
KEFONFAP_00572 6.7e-156 lacG G Binding-protein-dependent transport system inner membrane component
KEFONFAP_00573 1.9e-263 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
KEFONFAP_00574 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KEFONFAP_00575 0.0 3.2.1.96 G Glycosyl hydrolase family 85
KEFONFAP_00576 6e-205 K helix_turn _helix lactose operon repressor
KEFONFAP_00577 6.1e-243 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KEFONFAP_00578 1.7e-256 S Metal-independent alpha-mannosidase (GH125)
KEFONFAP_00579 1.1e-31
KEFONFAP_00580 2.6e-129 C Putative TM nitroreductase
KEFONFAP_00581 4.9e-168 EG EamA-like transporter family
KEFONFAP_00582 2e-70 pdxH S Pfam:Pyridox_oxidase
KEFONFAP_00583 2.9e-232 L ribosomal rna small subunit methyltransferase
KEFONFAP_00584 5.4e-166 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KEFONFAP_00585 5.3e-170 corA P CorA-like Mg2+ transporter protein
KEFONFAP_00586 2.3e-159 ET Bacterial periplasmic substrate-binding proteins
KEFONFAP_00587 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEFONFAP_00588 4.9e-81 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
KEFONFAP_00589 2.6e-308 comE S Competence protein
KEFONFAP_00590 9e-173 holA 2.7.7.7 L DNA polymerase III delta subunit
KEFONFAP_00591 2.6e-87 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
KEFONFAP_00592 1.9e-158 yeaZ 2.3.1.234 O Glycoprotease family
KEFONFAP_00593 1.4e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
KEFONFAP_00594 6.2e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KEFONFAP_00596 0.0 V FtsX-like permease family
KEFONFAP_00597 3.3e-124 V ABC transporter
KEFONFAP_00598 7.7e-109 K Bacterial regulatory proteins, tetR family
KEFONFAP_00599 1e-136 L PFAM Relaxase mobilization nuclease family protein
KEFONFAP_00600 5.1e-142 S Fic/DOC family
KEFONFAP_00605 9e-87 2.7.11.1 S HipA-like C-terminal domain
KEFONFAP_00606 3.7e-18 L Belongs to the 'phage' integrase family
KEFONFAP_00607 3.2e-27 yjdF S Protein of unknown function (DUF2992)
KEFONFAP_00608 2.3e-176 V Abi-like protein
KEFONFAP_00609 0.0 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
KEFONFAP_00610 3.2e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KEFONFAP_00612 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KEFONFAP_00613 1.1e-231 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KEFONFAP_00614 6.6e-251 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KEFONFAP_00615 1.9e-214 ykiI
KEFONFAP_00617 6.2e-20 tag 3.2.2.20 L Methyladenine glycosylase
KEFONFAP_00619 3.5e-120 S GyrI-like small molecule binding domain
KEFONFAP_00620 6.9e-89 K Putative zinc ribbon domain
KEFONFAP_00621 1.3e-25 zntR K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
KEFONFAP_00622 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KEFONFAP_00623 4e-127 3.6.1.13 L NUDIX domain
KEFONFAP_00624 5.1e-178 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
KEFONFAP_00625 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KEFONFAP_00626 1.2e-122 pdtaR T Response regulator receiver domain protein
KEFONFAP_00628 9.1e-107 aspA 3.6.1.13 L NUDIX domain
KEFONFAP_00629 2.7e-274 pyk 2.7.1.40 G Pyruvate kinase
KEFONFAP_00630 2.1e-177 terC P Integral membrane protein, TerC family
KEFONFAP_00631 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KEFONFAP_00632 2.3e-105 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KEFONFAP_00633 1.2e-253 rpsA J Ribosomal protein S1
KEFONFAP_00634 1.1e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KEFONFAP_00635 3e-183 P Zinc-uptake complex component A periplasmic
KEFONFAP_00636 1.9e-161 znuC P ATPases associated with a variety of cellular activities
KEFONFAP_00637 4.4e-136 znuB U ABC 3 transport family
KEFONFAP_00638 1.1e-87 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KEFONFAP_00639 2.1e-100 carD K CarD-like/TRCF domain
KEFONFAP_00640 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KEFONFAP_00641 1e-128 T Response regulator receiver domain protein
KEFONFAP_00642 9.8e-197 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KEFONFAP_00643 6.5e-122 ctsW S Phosphoribosyl transferase domain
KEFONFAP_00644 2.2e-148 cof 5.2.1.8 T Eukaryotic phosphomannomutase
KEFONFAP_00645 6.3e-78 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
KEFONFAP_00646 1.1e-262
KEFONFAP_00647 0.0 S Glycosyl transferase, family 2
KEFONFAP_00648 1.8e-55 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KEFONFAP_00649 2.1e-204 K Cell envelope-related transcriptional attenuator domain
KEFONFAP_00650 0.0 D FtsK/SpoIIIE family
KEFONFAP_00651 4.9e-47 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KEFONFAP_00652 7.5e-280 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KEFONFAP_00653 5.9e-145 yplQ S Haemolysin-III related
KEFONFAP_00654 4.4e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KEFONFAP_00655 1.4e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
KEFONFAP_00656 6.7e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
KEFONFAP_00657 3.2e-93
KEFONFAP_00658 2.5e-40 int8 L Phage integrase family
KEFONFAP_00659 2.6e-87 int8 L Phage integrase family
KEFONFAP_00662 1.3e-07
KEFONFAP_00665 1.1e-33
KEFONFAP_00666 2.3e-07
KEFONFAP_00667 1.6e-121 XK27_00240 K Fic/DOC family
KEFONFAP_00669 3.9e-87 L PFAM Integrase catalytic
KEFONFAP_00670 8.8e-49 L PFAM Integrase catalytic
KEFONFAP_00671 3.8e-147 K helix_turn _helix lactose operon repressor
KEFONFAP_00672 7.9e-237 bfrA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
KEFONFAP_00673 7.4e-258 M Protein of unknown function (DUF2961)
KEFONFAP_00674 4.4e-128 P Binding-protein-dependent transport systems inner membrane component
KEFONFAP_00675 3.3e-126 P Binding-protein-dependent transport system inner membrane component
KEFONFAP_00676 8.6e-211 G Bacterial extracellular solute-binding protein
KEFONFAP_00677 2.4e-88 pin L Resolvase, N terminal domain
KEFONFAP_00678 9.2e-45 L Helix-turn-helix domain
KEFONFAP_00679 2.8e-80 insK L Integrase core domain
KEFONFAP_00680 2.6e-81 L HTH-like domain
KEFONFAP_00682 5.8e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KEFONFAP_00683 6.3e-102 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
KEFONFAP_00684 1.6e-63 divIC D Septum formation initiator
KEFONFAP_00685 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KEFONFAP_00686 1e-178 1.1.1.65 C Aldo/keto reductase family
KEFONFAP_00687 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KEFONFAP_00688 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KEFONFAP_00689 4.3e-90 2.3.1.183 M Acetyltransferase (GNAT) domain
KEFONFAP_00690 0.0 S Uncharacterised protein family (UPF0182)
KEFONFAP_00691 8.6e-12 P Zinc-uptake complex component A periplasmic
KEFONFAP_00692 1.8e-151 P Zinc-uptake complex component A periplasmic
KEFONFAP_00694 6.4e-167 ycgR S Predicted permease
KEFONFAP_00695 8e-130 S TIGRFAM TIGR03943 family protein
KEFONFAP_00696 7.8e-137 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KEFONFAP_00697 3e-96
KEFONFAP_00698 2.9e-235 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KEFONFAP_00699 8.6e-284 thrC 4.2.3.1 E Threonine synthase N terminus
KEFONFAP_00700 3.1e-196 S Protein of unknown function (DUF1648)
KEFONFAP_00701 7.8e-71 K helix_turn_helix gluconate operon transcriptional repressor
KEFONFAP_00702 8.8e-25 pacL2 3.6.3.8 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KEFONFAP_00703 3.7e-107
KEFONFAP_00704 1.7e-120 S ABC-2 family transporter protein
KEFONFAP_00705 1.1e-172 V ATPases associated with a variety of cellular activities
KEFONFAP_00706 4.8e-58 K helix_turn_helix gluconate operon transcriptional repressor
KEFONFAP_00707 2.3e-18 J Acetyltransferase (GNAT) domain
KEFONFAP_00708 6e-13 J Acetyltransferase (GNAT) domain
KEFONFAP_00709 5e-119 S Haloacid dehalogenase-like hydrolase
KEFONFAP_00710 0.0 recN L May be involved in recombinational repair of damaged DNA
KEFONFAP_00711 9.6e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KEFONFAP_00712 1.9e-41 trkB P Cation transport protein
KEFONFAP_00713 1.3e-49 trkA P TrkA-N domain
KEFONFAP_00714 1.4e-95
KEFONFAP_00715 5.5e-141 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KEFONFAP_00717 3.2e-200 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KEFONFAP_00718 1.9e-171 L Tetratricopeptide repeat
KEFONFAP_00719 2.6e-255 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KEFONFAP_00720 9.1e-82 S Protein of unknown function (DUF975)
KEFONFAP_00721 3.9e-139 S Putative ABC-transporter type IV
KEFONFAP_00722 4.6e-102 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KEFONFAP_00723 3.3e-64 M1-798 P Rhodanese Homology Domain
KEFONFAP_00724 5e-145 moeB 2.7.7.80 H ThiF family
KEFONFAP_00725 1.8e-156 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KEFONFAP_00726 7.9e-28 thiS 2.8.1.10 H ThiS family
KEFONFAP_00727 3e-281 argH 4.3.2.1 E argininosuccinate lyase
KEFONFAP_00728 1.2e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KEFONFAP_00729 5.9e-83 argR K Regulates arginine biosynthesis genes
KEFONFAP_00730 3.9e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KEFONFAP_00731 1.3e-248 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
KEFONFAP_00732 8.2e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KEFONFAP_00733 2.6e-211 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KEFONFAP_00734 3e-201 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KEFONFAP_00735 4.8e-93
KEFONFAP_00736 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
KEFONFAP_00737 5e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KEFONFAP_00738 7.9e-160 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEFONFAP_00739 1.8e-162 cbiQ P Cobalt transport protein
KEFONFAP_00740 7e-278 ykoD P ATPases associated with a variety of cellular activities
KEFONFAP_00741 1.8e-107 ykoE S ABC-type cobalt transport system, permease component
KEFONFAP_00742 4.4e-258 argE E Peptidase dimerisation domain
KEFONFAP_00743 2e-101 S Protein of unknown function (DUF3043)
KEFONFAP_00744 7.6e-272 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KEFONFAP_00745 8.6e-142 S Domain of unknown function (DUF4191)
KEFONFAP_00746 2.3e-281 glnA 6.3.1.2 E glutamine synthetase
KEFONFAP_00747 8.1e-202 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KEFONFAP_00748 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KEFONFAP_00749 0.0 S Tetratricopeptide repeat
KEFONFAP_00750 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KEFONFAP_00751 1e-18 2.8.2.22 S Arylsulfotransferase Ig-like domain
KEFONFAP_00752 3.7e-140 bioM P ATPases associated with a variety of cellular activities
KEFONFAP_00753 1.4e-223 E Aminotransferase class I and II
KEFONFAP_00754 1.5e-189 P NMT1/THI5 like
KEFONFAP_00755 3.8e-134 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
KEFONFAP_00756 3.1e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KEFONFAP_00757 8.5e-128 recO L Involved in DNA repair and RecF pathway recombination
KEFONFAP_00758 0.0 I acetylesterase activity
KEFONFAP_00759 5.3e-231 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KEFONFAP_00760 1.7e-221 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KEFONFAP_00761 1e-205 2.7.11.1 NU Tfp pilus assembly protein FimV
KEFONFAP_00763 1.6e-73 S Protein of unknown function (DUF3052)
KEFONFAP_00764 1.7e-157 lon T Belongs to the peptidase S16 family
KEFONFAP_00765 3.1e-293 S Zincin-like metallopeptidase
KEFONFAP_00766 3.8e-290 uvrD2 3.6.4.12 L DNA helicase
KEFONFAP_00767 5.5e-300 mphA S Aminoglycoside phosphotransferase
KEFONFAP_00768 4.7e-32 S Protein of unknown function (DUF3107)
KEFONFAP_00769 1.5e-169 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
KEFONFAP_00770 3.8e-128 S Vitamin K epoxide reductase
KEFONFAP_00771 6e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
KEFONFAP_00772 5.7e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KEFONFAP_00773 2.9e-159 S Patatin-like phospholipase
KEFONFAP_00774 5.1e-59 S Domain of unknown function (DUF4143)
KEFONFAP_00775 7.2e-116 XK27_08050 O prohibitin homologues
KEFONFAP_00776 2.7e-08 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
KEFONFAP_00777 1.2e-41 XAC3035 O Glutaredoxin
KEFONFAP_00778 2.6e-233 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KEFONFAP_00779 7.9e-126 ypfH S Phospholipase/Carboxylesterase
KEFONFAP_00780 0.0 tetP J Elongation factor G, domain IV
KEFONFAP_00782 3.7e-136 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
KEFONFAP_00783 2.4e-104 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KEFONFAP_00784 5.7e-169 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KEFONFAP_00785 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
KEFONFAP_00786 2.2e-240 carA 6.3.5.5 F Belongs to the CarA family
KEFONFAP_00787 1.5e-92 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KEFONFAP_00788 3.9e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KEFONFAP_00789 1.4e-127 ybbL V ATPases associated with a variety of cellular activities
KEFONFAP_00790 7.1e-136 ybbM V Uncharacterised protein family (UPF0014)
KEFONFAP_00791 0.0 T Diguanylate cyclase, GGDEF domain
KEFONFAP_00792 9.1e-253 3.2.1.14 GH18 S Carbohydrate binding domain
KEFONFAP_00793 0.0 M probably involved in cell wall
KEFONFAP_00795 7.4e-48 4.1.1.44 L Cupin 2, conserved barrel domain protein
KEFONFAP_00796 1.6e-183 S Membrane transport protein
KEFONFAP_00797 2.4e-40 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KEFONFAP_00798 5.7e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KEFONFAP_00800 5.1e-122 magIII L endonuclease III
KEFONFAP_00801 5.7e-242 vbsD V MatE
KEFONFAP_00802 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KEFONFAP_00803 3.8e-138 K LysR substrate binding domain
KEFONFAP_00804 9.5e-216 EGP Major Facilitator Superfamily
KEFONFAP_00805 7.3e-156 K LysR substrate binding domain
KEFONFAP_00806 9.9e-217 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KEFONFAP_00808 9.2e-144 K helix_turn _helix lactose operon repressor
KEFONFAP_00809 0.0 3.2.1.25 G beta-mannosidase
KEFONFAP_00810 1e-137 dppF E ABC transporter
KEFONFAP_00811 5e-141 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
KEFONFAP_00812 5.3e-155 EP Binding-protein-dependent transport system inner membrane component
KEFONFAP_00813 1.3e-174 EP Binding-protein-dependent transport system inner membrane component
KEFONFAP_00814 1.7e-299 E Bacterial extracellular solute-binding proteins, family 5 Middle
KEFONFAP_00815 1.1e-237 bglA 3.2.1.21 G Glycosyl hydrolase family 1
KEFONFAP_00816 4.2e-147 E GDSL-like Lipase/Acylhydrolase family
KEFONFAP_00817 7.1e-174 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
KEFONFAP_00818 2.7e-77 KT Transcriptional regulatory protein, C terminal
KEFONFAP_00819 7.9e-35
KEFONFAP_00820 1.1e-253 S Domain of unknown function (DUF4143)
KEFONFAP_00821 1.1e-197 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
KEFONFAP_00822 1.8e-75 K MerR family regulatory protein
KEFONFAP_00823 8.4e-88 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEFONFAP_00824 7.3e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEFONFAP_00825 2.9e-30 S Psort location CytoplasmicMembrane, score
KEFONFAP_00827 1e-185 MA20_14895 S Conserved hypothetical protein 698
KEFONFAP_00828 3e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
KEFONFAP_00829 1e-128 tmp1 S Domain of unknown function (DUF4391)
KEFONFAP_00830 6.2e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KEFONFAP_00831 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KEFONFAP_00832 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KEFONFAP_00833 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KEFONFAP_00834 6.6e-111 yocS S SBF-like CPA transporter family (DUF4137)
KEFONFAP_00836 2.3e-195 ltaE 4.1.2.48 E Beta-eliminating lyase
KEFONFAP_00837 2.2e-218 M Glycosyl transferase 4-like domain
KEFONFAP_00838 1.1e-87 mtnE 2.6.1.83 E Aminotransferase class I and II
KEFONFAP_00839 6.2e-44 L Integrase core domain
KEFONFAP_00840 2.4e-14 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KEFONFAP_00841 8.3e-131 S Sulfite exporter TauE/SafE
KEFONFAP_00842 1.4e-62 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFONFAP_00844 6.2e-236 EGP Major facilitator Superfamily
KEFONFAP_00845 1.5e-106 3.1.3.27 E haloacid dehalogenase-like hydrolase
KEFONFAP_00846 1.4e-161 3.1.3.73 G Phosphoglycerate mutase family
KEFONFAP_00847 4.2e-234 rutG F Permease family
KEFONFAP_00848 1.8e-308 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
KEFONFAP_00849 6.2e-254 nplT G Alpha amylase, catalytic domain
KEFONFAP_00850 2.8e-188 pit P Phosphate transporter family
KEFONFAP_00851 4.3e-112 MA20_27875 P Protein of unknown function DUF47
KEFONFAP_00852 1.8e-113 K helix_turn_helix, Lux Regulon
KEFONFAP_00853 1.1e-216 T Histidine kinase
KEFONFAP_00854 1.8e-10 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
KEFONFAP_00855 5.1e-176 V ATPases associated with a variety of cellular activities
KEFONFAP_00856 3.3e-220 V ABC-2 family transporter protein
KEFONFAP_00857 3.6e-226 V ABC-2 family transporter protein
KEFONFAP_00858 1e-281 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KEFONFAP_00859 2e-47 E lipolytic protein G-D-S-L family
KEFONFAP_00860 1.9e-196
KEFONFAP_00861 1.1e-110 3.4.13.21 E Peptidase family S51
KEFONFAP_00862 1e-105 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
KEFONFAP_00863 3.1e-162 M pfam nlp p60
KEFONFAP_00864 1.1e-152 I Serine aminopeptidase, S33
KEFONFAP_00865 3.4e-45 S Protein of unknown function (DUF2975)
KEFONFAP_00866 3.7e-241 pbuX F Permease family
KEFONFAP_00867 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KEFONFAP_00868 0.0 pcrA 3.6.4.12 L DNA helicase
KEFONFAP_00869 6.9e-63 S Domain of unknown function (DUF4418)
KEFONFAP_00870 8.2e-216 V FtsX-like permease family
KEFONFAP_00871 4.1e-151 lolD V ABC transporter
KEFONFAP_00872 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KEFONFAP_00873 1.3e-150 S Peptidase C26
KEFONFAP_00874 5.7e-70 3.5.4.5 F cytidine deaminase activity
KEFONFAP_00875 1.5e-45 sdpI S SdpI/YhfL protein family
KEFONFAP_00876 1.2e-111 E Transglutaminase-like superfamily
KEFONFAP_00877 3e-65 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KEFONFAP_00878 1.2e-48 relB L RelB antitoxin
KEFONFAP_00879 1.9e-129 pgm3 G Phosphoglycerate mutase family
KEFONFAP_00880 2.3e-55 WQ51_05790 S Bacterial protein of unknown function (DUF948)
KEFONFAP_00881 1.6e-35
KEFONFAP_00882 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KEFONFAP_00883 2.7e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KEFONFAP_00884 1.1e-193 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KEFONFAP_00885 1.8e-70 3.4.23.43 S Type IV leader peptidase family
KEFONFAP_00886 4.7e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KEFONFAP_00887 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KEFONFAP_00888 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KEFONFAP_00889 1.3e-94 K Psort location Cytoplasmic, score
KEFONFAP_00890 2.3e-24 xerH L Phage integrase family
KEFONFAP_00892 0.0 topB 5.99.1.2 L DNA topoisomerase
KEFONFAP_00893 6.6e-206 dcm 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KEFONFAP_00894 0.0 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
KEFONFAP_00895 1.4e-267 hsdBM 2.1.1.72 L Eco57I restriction-modification methylase
KEFONFAP_00896 3.8e-184 pstIR 2.1.1.72, 3.1.21.4 L BsuBI/PstI restriction endonuclease C-terminus
KEFONFAP_00897 1.3e-224
KEFONFAP_00899 1.4e-69 L Phage integrase family
KEFONFAP_00900 2.9e-84 L Phage integrase family
KEFONFAP_00901 9e-36 M Peptidase family M23
KEFONFAP_00902 2.3e-256 G ABC transporter substrate-binding protein
KEFONFAP_00903 6.7e-242 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
KEFONFAP_00904 3.8e-207 guaB 1.1.1.205 F IMP dehydrogenase family protein
KEFONFAP_00905 3.3e-91
KEFONFAP_00906 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
KEFONFAP_00907 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KEFONFAP_00908 4.1e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
KEFONFAP_00909 8.5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KEFONFAP_00910 6.3e-134 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KEFONFAP_00911 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KEFONFAP_00912 2.4e-173 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
KEFONFAP_00913 5.1e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KEFONFAP_00914 1.2e-52 3.5.1.124 S DJ-1/PfpI family
KEFONFAP_00915 7.9e-16 3.5.1.124 S DJ-1/PfpI family
KEFONFAP_00916 3.9e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KEFONFAP_00917 1.5e-70 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KEFONFAP_00918 5.4e-297 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KEFONFAP_00919 1.1e-91 yijF S Domain of unknown function (DUF1287)
KEFONFAP_00920 6.5e-158 3.6.4.12
KEFONFAP_00921 2.7e-73
KEFONFAP_00922 1.9e-64 yeaO K Protein of unknown function, DUF488
KEFONFAP_00924 2.3e-295 mmuP E amino acid
KEFONFAP_00925 6.3e-20 G Major facilitator Superfamily
KEFONFAP_00926 1.4e-41 2.6.1.76 EGP Major Facilitator Superfamily
KEFONFAP_00927 3.1e-92 yidC U Membrane protein insertase, YidC Oxa1 family
KEFONFAP_00928 8.4e-116 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
KEFONFAP_00929 3e-31 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KEFONFAP_00930 5.4e-93
KEFONFAP_00931 1.5e-22
KEFONFAP_00932 2.5e-15 fic D Fic/DOC family
KEFONFAP_00933 6.4e-122 V ATPases associated with a variety of cellular activities
KEFONFAP_00934 4.6e-129
KEFONFAP_00935 1.8e-102
KEFONFAP_00936 4.3e-129 S EamA-like transporter family
KEFONFAP_00937 2.6e-37
KEFONFAP_00938 1.2e-46 S Protein of unknown function (DUF2089)
KEFONFAP_00939 3.5e-90 ydaF_1 J Acetyltransferase (GNAT) domain
KEFONFAP_00940 9.2e-95 K helix_turn_helix, Lux Regulon
KEFONFAP_00941 1.5e-67 2.7.13.3 T Histidine kinase
KEFONFAP_00942 5.6e-54 sdpI S SdpI/YhfL protein family
KEFONFAP_00943 6e-99 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
KEFONFAP_00944 1.6e-62 rplQ J Ribosomal protein L17
KEFONFAP_00945 3.4e-183 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEFONFAP_00946 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KEFONFAP_00947 9.5e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KEFONFAP_00948 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KEFONFAP_00949 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KEFONFAP_00950 1.1e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KEFONFAP_00951 1.4e-245 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KEFONFAP_00952 8.1e-76 rplO J binds to the 23S rRNA
KEFONFAP_00953 9.2e-26 rpmD J Ribosomal protein L30p/L7e
KEFONFAP_00954 6.7e-96 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KEFONFAP_00955 2.4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KEFONFAP_00956 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KEFONFAP_00957 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KEFONFAP_00958 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KEFONFAP_00959 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KEFONFAP_00960 1.3e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KEFONFAP_00961 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KEFONFAP_00962 6.4e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KEFONFAP_00963 4.1e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
KEFONFAP_00964 2.2e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KEFONFAP_00965 1.7e-100 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KEFONFAP_00966 5.7e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KEFONFAP_00967 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KEFONFAP_00968 1.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KEFONFAP_00969 7.5e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KEFONFAP_00970 3.1e-116 rplD J Forms part of the polypeptide exit tunnel
KEFONFAP_00971 8.7e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KEFONFAP_00972 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
KEFONFAP_00973 8.2e-137 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KEFONFAP_00974 4.3e-145 ywiC S YwiC-like protein
KEFONFAP_00975 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KEFONFAP_00976 3.1e-170 rhaR_1 K helix_turn_helix, arabinose operon control protein
KEFONFAP_00977 2.2e-193 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
KEFONFAP_00978 2.7e-196 EGP Major facilitator Superfamily
KEFONFAP_00979 1.6e-213 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
KEFONFAP_00980 6e-75 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFONFAP_00981 2.2e-233 EGP Major facilitator Superfamily
KEFONFAP_00982 2.3e-179 tdh 1.1.1.14 C Zinc-binding dehydrogenase
KEFONFAP_00983 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KEFONFAP_00984 3.7e-82 rpsI J Belongs to the universal ribosomal protein uS9 family
KEFONFAP_00985 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KEFONFAP_00986 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
KEFONFAP_00987 8.4e-117
KEFONFAP_00988 1.1e-110 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
KEFONFAP_00989 5e-182 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEFONFAP_00990 1.7e-15 M Bacterial capsule synthesis protein PGA_cap
KEFONFAP_00991 8.1e-39 M Bacterial capsule synthesis protein PGA_cap
KEFONFAP_00992 3.5e-103 malC G Binding-protein-dependent transport system inner membrane component
KEFONFAP_00993 1.2e-167 G ABC transporter permease
KEFONFAP_00994 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KEFONFAP_00995 1.7e-259 G Bacterial extracellular solute-binding protein
KEFONFAP_00996 4e-278 G Bacterial extracellular solute-binding protein
KEFONFAP_00997 4.5e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KEFONFAP_00998 1.9e-292 E ABC transporter, substrate-binding protein, family 5
KEFONFAP_00999 7.4e-167 P Binding-protein-dependent transport system inner membrane component
KEFONFAP_01000 1.1e-146 EP Binding-protein-dependent transport system inner membrane component
KEFONFAP_01001 5.5e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
KEFONFAP_01002 2.4e-136 sapF E ATPases associated with a variety of cellular activities
KEFONFAP_01003 1.8e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
KEFONFAP_01004 3.5e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KEFONFAP_01005 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KEFONFAP_01006 2.7e-93 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KEFONFAP_01007 6.5e-104 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KEFONFAP_01008 4.3e-272 yhdG E aromatic amino acid transport protein AroP K03293
KEFONFAP_01009 2.9e-262 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KEFONFAP_01010 2.9e-243 dgt 3.1.5.1 F Phosphohydrolase-associated domain
KEFONFAP_01011 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KEFONFAP_01012 1.8e-69 S PIN domain
KEFONFAP_01013 1e-34
KEFONFAP_01014 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KEFONFAP_01015 1.1e-115 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KEFONFAP_01016 1.6e-293 EK Alanine-glyoxylate amino-transferase
KEFONFAP_01017 3.8e-210 ybiR P Citrate transporter
KEFONFAP_01018 3.3e-30
KEFONFAP_01019 3.5e-42 G Alpha-L-arabinofuranosidase C-terminal domain
KEFONFAP_01020 3.1e-156 K Helix-turn-helix domain, rpiR family
KEFONFAP_01023 4.3e-258 G Bacterial extracellular solute-binding protein
KEFONFAP_01024 9.9e-225 K helix_turn _helix lactose operon repressor
KEFONFAP_01025 5.7e-51 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
KEFONFAP_01026 8.1e-31
KEFONFAP_01027 4.1e-142
KEFONFAP_01028 1.1e-65 S PrgI family protein
KEFONFAP_01029 0.0 trsE U type IV secretory pathway VirB4
KEFONFAP_01030 1e-258 isp2 3.2.1.96 M CHAP domain
KEFONFAP_01031 2e-185
KEFONFAP_01033 3.4e-65 S Putative amidase domain
KEFONFAP_01034 1.5e-99 S Putative amidase domain
KEFONFAP_01035 0.0 U Type IV secretory system Conjugative DNA transfer
KEFONFAP_01036 6.6e-59
KEFONFAP_01037 3.5e-46
KEFONFAP_01038 9.9e-124
KEFONFAP_01039 9.4e-259 ard S Antirestriction protein (ArdA)
KEFONFAP_01040 7.1e-165
KEFONFAP_01041 1.5e-161 S Protein of unknown function (DUF3801)
KEFONFAP_01042 1.6e-271 rlx U Relaxase/Mobilisation nuclease domain
KEFONFAP_01043 3.5e-70 S Bacterial mobilisation protein (MobC)
KEFONFAP_01044 1.1e-84
KEFONFAP_01045 1.3e-46
KEFONFAP_01046 1.4e-265 K ParB-like nuclease domain
KEFONFAP_01047 1.1e-107 S Domain of unknown function (DUF4192)
KEFONFAP_01048 1.6e-233 T Histidine kinase
KEFONFAP_01049 1.9e-124 K helix_turn_helix, Lux Regulon
KEFONFAP_01050 1.9e-121 V ABC transporter
KEFONFAP_01051 1.4e-17
KEFONFAP_01052 4.1e-292 E Asparagine synthase
KEFONFAP_01053 3.2e-35 E Asparagine synthase
KEFONFAP_01054 2.7e-308 V ABC transporter transmembrane region
KEFONFAP_01056 4.9e-164 spaB S Thiopeptide-type bacteriocin biosynthesis domain protein
KEFONFAP_01057 5.4e-107 V Psort location Cytoplasmic, score
KEFONFAP_01059 8.1e-116 V VanZ like family
KEFONFAP_01060 2e-168 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KEFONFAP_01061 3.7e-72 I Sterol carrier protein
KEFONFAP_01062 2.5e-224 EGP Major Facilitator Superfamily
KEFONFAP_01063 3.2e-209 2.7.13.3 T Histidine kinase
KEFONFAP_01064 5.5e-113 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KEFONFAP_01065 1.2e-38 S Protein of unknown function (DUF3073)
KEFONFAP_01066 5.5e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEFONFAP_01067 3.3e-289 S Amidohydrolase family
KEFONFAP_01068 3.2e-157 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KEFONFAP_01069 4e-44 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KEFONFAP_01070 0.0 yjjP S Threonine/Serine exporter, ThrE
KEFONFAP_01071 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KEFONFAP_01072 1.9e-308 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KEFONFAP_01073 2.5e-92 S AAA domain
KEFONFAP_01074 0.0 yliE T Putative diguanylate phosphodiesterase
KEFONFAP_01075 2.3e-108 S Domain of unknown function (DUF4956)
KEFONFAP_01076 7.4e-152 P VTC domain
KEFONFAP_01077 3.1e-304 cotH M CotH kinase protein
KEFONFAP_01078 2.1e-272 pelG S Putative exopolysaccharide Exporter (EPS-E)
KEFONFAP_01079 4.5e-252 pelF GT4 M Domain of unknown function (DUF3492)
KEFONFAP_01080 1.3e-14 pelF GT4 M Domain of unknown function (DUF3492)
KEFONFAP_01081 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
KEFONFAP_01082 5.7e-161
KEFONFAP_01083 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
KEFONFAP_01084 3.6e-225 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KEFONFAP_01085 3.6e-137 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KEFONFAP_01086 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
KEFONFAP_01087 8.2e-222 I alpha/beta hydrolase fold
KEFONFAP_01088 2.8e-252 Q D-alanine [D-alanyl carrier protein] ligase activity
KEFONFAP_01089 6.6e-111 Q D-alanine [D-alanyl carrier protein] ligase activity
KEFONFAP_01090 1.1e-101 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
KEFONFAP_01091 1.2e-13 C Aldo/keto reductase family
KEFONFAP_01092 3.5e-32
KEFONFAP_01093 1.2e-299 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
KEFONFAP_01094 7.9e-293 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KEFONFAP_01095 1.6e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KEFONFAP_01096 9.1e-242 purD 6.3.4.13 F Belongs to the GARS family
KEFONFAP_01097 1.5e-294 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
KEFONFAP_01098 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KEFONFAP_01099 3.2e-143 P Zinc-uptake complex component A periplasmic
KEFONFAP_01100 8.9e-69 zur P Belongs to the Fur family
KEFONFAP_01101 1.1e-222 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KEFONFAP_01102 6.2e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KEFONFAP_01103 2.4e-181 adh3 C Zinc-binding dehydrogenase
KEFONFAP_01104 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KEFONFAP_01105 5.6e-278 macB_8 V MacB-like periplasmic core domain
KEFONFAP_01106 8e-177 M Conserved repeat domain
KEFONFAP_01107 4e-134 V ATPases associated with a variety of cellular activities
KEFONFAP_01108 2.1e-185 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
KEFONFAP_01109 8.9e-90 K MarR family
KEFONFAP_01110 0.0 V ABC transporter, ATP-binding protein
KEFONFAP_01111 0.0 V ABC transporter transmembrane region
KEFONFAP_01112 2.7e-135 rbsR K helix_turn _helix lactose operon repressor
KEFONFAP_01113 6.8e-139 rihA_2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KEFONFAP_01114 3.9e-169 EGP Major Facilitator Superfamily
KEFONFAP_01115 1.1e-135 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KEFONFAP_01116 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KEFONFAP_01117 6.3e-61 L Transposase
KEFONFAP_01118 0.0 cas3 L DEAD-like helicases superfamily
KEFONFAP_01119 1.5e-137 cas5d S CRISPR-associated protein (Cas_Cas5)
KEFONFAP_01120 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
KEFONFAP_01121 8.7e-156 csd2 L CRISPR-associated protein Cas7
KEFONFAP_01122 2.1e-131 cas4 3.1.12.1 L Domain of unknown function DUF83
KEFONFAP_01123 4.2e-197 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KEFONFAP_01124 1.8e-36 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KEFONFAP_01127 2e-30 lacS G Psort location CytoplasmicMembrane, score 10.00
KEFONFAP_01128 7.9e-15 L Phage integrase family
KEFONFAP_01129 1.3e-26 S PIN domain
KEFONFAP_01130 2.4e-44 S Helix-turn-helix domain
KEFONFAP_01131 0.0 XK27_00515 D Cell surface antigen C-terminus
KEFONFAP_01132 1.3e-119 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
KEFONFAP_01133 3.4e-94 K FR47-like protein
KEFONFAP_01134 1.8e-281 S ATPases associated with a variety of cellular activities
KEFONFAP_01135 6.8e-40
KEFONFAP_01136 3.3e-101 parA D AAA domain
KEFONFAP_01137 1.3e-81 S Transcription factor WhiB
KEFONFAP_01138 4.7e-214 S Helix-turn-helix domain
KEFONFAP_01139 5.6e-10 S Helix-turn-helix domain
KEFONFAP_01141 6e-68
KEFONFAP_01142 3.1e-234 L Phage integrase family
KEFONFAP_01143 1.6e-80
KEFONFAP_01144 3.9e-128
KEFONFAP_01145 3.6e-20 S Protein of unknown function (DUF2599)
KEFONFAP_01147 4.1e-245 L Phage integrase family
KEFONFAP_01148 1.4e-35 G Glycosyl hydrolase family 20, domain 2
KEFONFAP_01149 1.8e-59 G Glycosyl hydrolase family 20, domain 2
KEFONFAP_01150 1.4e-140 G Glycosyl hydrolase family 20, domain 2
KEFONFAP_01151 7.6e-30 lacS G Psort location CytoplasmicMembrane, score 10.00
KEFONFAP_01153 2e-120 V ATPases associated with a variety of cellular activities
KEFONFAP_01154 2.2e-99
KEFONFAP_01155 6.8e-81
KEFONFAP_01156 3.2e-29 spaB S Lantibiotic dehydratase, C terminus
KEFONFAP_01157 4.1e-18 V Lanthionine synthetase C-like protein
KEFONFAP_01158 9.6e-41 V ATPase activity
KEFONFAP_01159 4.9e-47 V ABC-2 type transporter
KEFONFAP_01160 0.0 sprF 4.6.1.1 M Cell surface antigen C-terminus
KEFONFAP_01162 7.8e-126 K Helix-turn-helix domain protein
KEFONFAP_01163 2.1e-12
KEFONFAP_01164 9.2e-71
KEFONFAP_01165 1.7e-35
KEFONFAP_01166 2.1e-103 parA D AAA domain
KEFONFAP_01167 8e-83 S Transcription factor WhiB
KEFONFAP_01168 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KEFONFAP_01169 4.5e-311 S L,D-transpeptidase catalytic domain
KEFONFAP_01170 1.5e-291 sufB O FeS assembly protein SufB
KEFONFAP_01171 7.3e-236 sufD O FeS assembly protein SufD
KEFONFAP_01172 7e-144 sufC O FeS assembly ATPase SufC
KEFONFAP_01173 5.5e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KEFONFAP_01174 4e-101 iscU C SUF system FeS assembly protein, NifU family
KEFONFAP_01175 3.2e-109 yitW S Iron-sulfur cluster assembly protein
KEFONFAP_01176 4.4e-241 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KEFONFAP_01177 3.3e-166 spoU 2.1.1.185 J SpoU rRNA Methylase family
KEFONFAP_01179 6.8e-148 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KEFONFAP_01180 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
KEFONFAP_01181 2.7e-216 phoH T PhoH-like protein
KEFONFAP_01182 4.7e-102 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KEFONFAP_01183 4.3e-248 corC S CBS domain
KEFONFAP_01184 2.8e-185 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KEFONFAP_01185 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KEFONFAP_01186 9e-204 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
KEFONFAP_01187 3e-42 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
KEFONFAP_01188 3.3e-232 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KEFONFAP_01189 9.2e-234 yhjX EGP Major facilitator Superfamily
KEFONFAP_01190 2.7e-93 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KEFONFAP_01191 1.6e-226 ilvE 2.6.1.42 E Amino-transferase class IV
KEFONFAP_01192 2.2e-141 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
KEFONFAP_01193 8.8e-139 S UPF0126 domain
KEFONFAP_01194 5.8e-34 rpsT J Binds directly to 16S ribosomal RNA
KEFONFAP_01195 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KEFONFAP_01196 4.1e-253 hemN H Involved in the biosynthesis of porphyrin-containing compound
KEFONFAP_01198 1.2e-191 K helix_turn _helix lactose operon repressor
KEFONFAP_01199 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
KEFONFAP_01200 1.4e-305 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KEFONFAP_01202 5.4e-44
KEFONFAP_01203 0.0 E ABC transporter, substrate-binding protein, family 5
KEFONFAP_01204 0.0 S Glycosyl hydrolases related to GH101 family, GH129
KEFONFAP_01205 8.6e-81
KEFONFAP_01206 7.3e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
KEFONFAP_01207 1.9e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
KEFONFAP_01208 1e-156 S Sucrose-6F-phosphate phosphohydrolase
KEFONFAP_01209 3.6e-94 bcp 1.11.1.15 O Redoxin
KEFONFAP_01210 1.2e-141
KEFONFAP_01211 2.2e-82 L Transposase, Mutator family
KEFONFAP_01213 4.4e-25
KEFONFAP_01214 1.5e-177 I alpha/beta hydrolase fold
KEFONFAP_01215 5e-90 S Appr-1'-p processing enzyme
KEFONFAP_01216 9.3e-146 S phosphoesterase or phosphohydrolase
KEFONFAP_01217 2e-140 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KEFONFAP_01219 1.3e-133 S Phospholipase/Carboxylesterase
KEFONFAP_01220 9.4e-200 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KEFONFAP_01221 5.8e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
KEFONFAP_01223 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KEFONFAP_01224 1.6e-162 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
KEFONFAP_01225 4.8e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KEFONFAP_01226 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
KEFONFAP_01227 1.6e-177 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KEFONFAP_01228 7e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
KEFONFAP_01229 9.1e-289 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KEFONFAP_01230 2.7e-174 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
KEFONFAP_01231 6.9e-158 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
KEFONFAP_01232 4e-181 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KEFONFAP_01233 5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KEFONFAP_01234 9e-29
KEFONFAP_01235 2.4e-217 MA20_36090 S Psort location Cytoplasmic, score 8.87
KEFONFAP_01236 9.4e-172 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
KEFONFAP_01237 9.4e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KEFONFAP_01238 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KEFONFAP_01239 6.4e-301 ybiT S ABC transporter
KEFONFAP_01240 1.2e-129 S Enoyl-(Acyl carrier protein) reductase
KEFONFAP_01241 6.1e-21 G ATPases associated with a variety of cellular activities
KEFONFAP_01242 1.1e-89 XK27_08585 S Hypothetical bacterial integral membrane protein (Trep_Strep)
KEFONFAP_01243 5.5e-233 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
KEFONFAP_01244 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KEFONFAP_01245 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KEFONFAP_01246 6.2e-190 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
KEFONFAP_01247 1.1e-178 rapZ S Displays ATPase and GTPase activities
KEFONFAP_01248 3.5e-169 whiA K May be required for sporulation
KEFONFAP_01249 1e-218 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
KEFONFAP_01250 6e-146 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KEFONFAP_01251 2.7e-33 secG U Preprotein translocase SecG subunit
KEFONFAP_01252 2.5e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KEFONFAP_01253 4.9e-159 S Sucrose-6F-phosphate phosphohydrolase
KEFONFAP_01254 1.2e-299 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
KEFONFAP_01255 2.5e-185
KEFONFAP_01256 3.3e-234 brnQ U Component of the transport system for branched-chain amino acids
KEFONFAP_01257 3.6e-202 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KEFONFAP_01258 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
KEFONFAP_01259 3.7e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KEFONFAP_01260 6.8e-212 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KEFONFAP_01261 9.6e-157 G Fructosamine kinase
KEFONFAP_01262 1.8e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KEFONFAP_01263 1.5e-133 S PAC2 family
KEFONFAP_01269 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KEFONFAP_01270 1.2e-111 hit 2.7.7.53 FG HIT domain
KEFONFAP_01271 2e-111 yebC K transcriptional regulatory protein
KEFONFAP_01272 2.7e-100 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KEFONFAP_01273 2.7e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KEFONFAP_01274 2.3e-198 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KEFONFAP_01275 3.6e-52 yajC U Preprotein translocase subunit
KEFONFAP_01276 3e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KEFONFAP_01277 3.1e-223 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KEFONFAP_01278 2.9e-165 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KEFONFAP_01279 4.7e-233
KEFONFAP_01280 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KEFONFAP_01281 4.1e-31
KEFONFAP_01282 4.7e-118 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KEFONFAP_01283 4.5e-143 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KEFONFAP_01284 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
KEFONFAP_01286 1.6e-162 supH S Sucrose-6F-phosphate phosphohydrolase
KEFONFAP_01287 2.5e-291 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
KEFONFAP_01288 0.0 pafB K WYL domain
KEFONFAP_01289 6.8e-53
KEFONFAP_01290 0.0 helY L DEAD DEAH box helicase
KEFONFAP_01291 5.1e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
KEFONFAP_01292 1.1e-138 pgp 3.1.3.18 S HAD-hyrolase-like
KEFONFAP_01293 2.6e-35
KEFONFAP_01294 1.5e-65
KEFONFAP_01295 1.1e-110 K helix_turn_helix, mercury resistance
KEFONFAP_01296 6.7e-75 garA T Inner membrane component of T3SS, cytoplasmic domain
KEFONFAP_01297 2.2e-140 S Bacterial protein of unknown function (DUF881)
KEFONFAP_01298 3.9e-35 sbp S Protein of unknown function (DUF1290)
KEFONFAP_01299 3.9e-168 S Bacterial protein of unknown function (DUF881)
KEFONFAP_01300 7.3e-104 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KEFONFAP_01301 8.7e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
KEFONFAP_01302 9.9e-42 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
KEFONFAP_01303 9.4e-113 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
KEFONFAP_01304 5.3e-186 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KEFONFAP_01305 4.6e-160 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KEFONFAP_01306 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KEFONFAP_01307 6.5e-133 S SOS response associated peptidase (SRAP)
KEFONFAP_01308 6.3e-154 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KEFONFAP_01309 2.6e-258 mmuP E amino acid
KEFONFAP_01311 3.5e-188 V VanZ like family
KEFONFAP_01312 4e-14 cefD 5.1.1.17 E Aminotransferase, class V
KEFONFAP_01313 1.5e-35 cefD 5.1.1.17 E Aminotransferase class-V
KEFONFAP_01314 4.5e-25 S Uncharacterized protein conserved in bacteria (DUF2316)
KEFONFAP_01315 3.3e-100 S Acetyltransferase (GNAT) domain
KEFONFAP_01316 2.5e-43 V MacB-like periplasmic core domain
KEFONFAP_01317 2.1e-39 relB L RelB antitoxin
KEFONFAP_01318 1.4e-49 S Bacterial toxin of type II toxin-antitoxin system, YafQ
KEFONFAP_01319 4.6e-26 2.7.13.3 T Histidine kinase
KEFONFAP_01320 8.9e-34 malC G Binding-protein-dependent transport system inner membrane component
KEFONFAP_01321 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KEFONFAP_01322 3.6e-191 K helix_turn _helix lactose operon repressor
KEFONFAP_01323 1.6e-165 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
KEFONFAP_01324 2.1e-140 L Protein of unknown function (DUF1524)
KEFONFAP_01325 1.8e-150 S Domain of unknown function (DUF4143)
KEFONFAP_01326 2.6e-231 mntH P H( )-stimulated, divalent metal cation uptake system
KEFONFAP_01327 3.3e-281 EGP Major facilitator Superfamily
KEFONFAP_01328 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
KEFONFAP_01329 2.8e-310 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KEFONFAP_01330 5.7e-109 3.1.3.48 T Low molecular weight phosphatase family
KEFONFAP_01331 1.3e-37 L Transposase and inactivated derivatives IS30 family
KEFONFAP_01332 7.9e-101 cps1D M Domain of unknown function (DUF4422)
KEFONFAP_01333 1.4e-223 glf 5.4.99.9 M UDP-galactopyranose mutase
KEFONFAP_01334 1.2e-27 L Integrase core domain
KEFONFAP_01335 4.9e-70 L IstB-like ATP binding protein
KEFONFAP_01336 1.7e-59 L IstB-like ATP binding protein
KEFONFAP_01337 9.3e-176 5.1.3.37 P Domain of unknown function (DUF4143)
KEFONFAP_01338 1.4e-49 L Transposase
KEFONFAP_01339 2.1e-24 L PFAM Integrase catalytic
KEFONFAP_01340 1.4e-131 L IstB-like ATP binding protein
KEFONFAP_01341 5.2e-211 L PFAM Integrase catalytic
KEFONFAP_01342 4.5e-66 L PFAM Integrase catalytic
KEFONFAP_01344 9.4e-97 K Transposase IS116 IS110 IS902
KEFONFAP_01345 1.5e-43 L Psort location Cytoplasmic, score
KEFONFAP_01346 1.3e-89 L Transposase
KEFONFAP_01347 5.6e-48 L Transposase, Mutator family
KEFONFAP_01348 8.8e-67
KEFONFAP_01349 7.9e-87
KEFONFAP_01350 1.6e-65 L Helix-turn-helix domain
KEFONFAP_01351 2.8e-243 nagA 3.5.1.25 G Amidohydrolase family
KEFONFAP_01352 1.2e-146 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KEFONFAP_01353 3.1e-173 2.7.1.2 GK ROK family
KEFONFAP_01354 5.5e-217 GK ROK family
KEFONFAP_01355 2.4e-158 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
KEFONFAP_01356 1.4e-251 gtr U Sugar (and other) transporter
KEFONFAP_01357 2.1e-311 P Domain of unknown function (DUF4976)
KEFONFAP_01358 1.2e-271 aslB C Iron-sulfur cluster-binding domain
KEFONFAP_01359 4.6e-106 S Sulfite exporter TauE/SafE
KEFONFAP_01360 5.9e-53 L Helix-turn-helix domain
KEFONFAP_01361 2.4e-50 L Transposase and inactivated derivatives IS30 family
KEFONFAP_01362 2.5e-218 L Transposase, Mutator family
KEFONFAP_01363 2.2e-51 S Phage derived protein Gp49-like (DUF891)
KEFONFAP_01364 3.3e-38 K Addiction module
KEFONFAP_01366 4.8e-80 ybfG M Domain of unknown function (DUF1906)
KEFONFAP_01367 7e-153 P Belongs to the ABC transporter superfamily
KEFONFAP_01368 2.1e-88 appC EP PFAM binding-protein-dependent transport systems inner membrane component
KEFONFAP_01369 4.7e-121 appB P PFAM binding-protein-dependent transport systems inner membrane component
KEFONFAP_01370 3.4e-191 oppA5 E family 5
KEFONFAP_01371 3.1e-22 trxB1 1.8.1.9 C Thioredoxin domain
KEFONFAP_01372 3.3e-68 trxB1 1.8.1.9 C Thioredoxin domain
KEFONFAP_01373 3.2e-166 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
KEFONFAP_01374 1.3e-232 malE G Bacterial extracellular solute-binding protein
KEFONFAP_01375 2.4e-251 malF G Binding-protein-dependent transport system inner membrane component
KEFONFAP_01376 2.6e-161 malG G Binding-protein-dependent transport system inner membrane component
KEFONFAP_01377 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KEFONFAP_01378 3.1e-173 S HAD-hyrolase-like
KEFONFAP_01379 4.2e-144 traX S TraX protein
KEFONFAP_01380 2.6e-194 K Psort location Cytoplasmic, score
KEFONFAP_01381 3.5e-28 L Helix-turn-helix domain
KEFONFAP_01382 1.1e-180 C Polysaccharide pyruvyl transferase
KEFONFAP_01383 2.2e-132 GT2 M Glycosyltransferase like family 2
KEFONFAP_01384 2.8e-148 1.13.11.79 C Psort location Cytoplasmic, score 8.87
KEFONFAP_01385 6.1e-175 wbbI M transferase activity, transferring glycosyl groups
KEFONFAP_01386 4.2e-222 S Psort location CytoplasmicMembrane, score 9.99
KEFONFAP_01387 2.4e-27 S Psort location CytoplasmicMembrane, score 9.99
KEFONFAP_01388 8.6e-155 S Glycosyl transferase family 2
KEFONFAP_01389 9.1e-60 cps1D M Domain of unknown function (DUF4422)
KEFONFAP_01390 2.5e-56
KEFONFAP_01391 2.2e-20
KEFONFAP_01392 3.5e-32
KEFONFAP_01394 4.8e-39 S AAA domain, putative AbiEii toxin, Type IV TA system
KEFONFAP_01395 1.1e-30 S AAA domain, putative AbiEii toxin, Type IV TA system
KEFONFAP_01396 4.7e-103 insK L Integrase core domain
KEFONFAP_01397 2.9e-15 S COG NOG14600 non supervised orthologous group
KEFONFAP_01398 9.2e-10
KEFONFAP_01399 4.8e-65 S Predicted membrane protein (DUF2142)
KEFONFAP_01400 1.1e-172 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KEFONFAP_01402 1.7e-190 M Glycosyltransferase like family 2
KEFONFAP_01403 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
KEFONFAP_01404 0.0 dnaK O Heat shock 70 kDa protein
KEFONFAP_01405 5.2e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KEFONFAP_01406 9.4e-157 dnaJ1 O DnaJ molecular chaperone homology domain
KEFONFAP_01407 2.7e-103 hspR K transcriptional regulator, MerR family
KEFONFAP_01408 3.1e-17 F Psort location CytoplasmicMembrane, score 10.00
KEFONFAP_01409 3.3e-114 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
KEFONFAP_01410 2.8e-140 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
KEFONFAP_01411 6.7e-127 S HAD hydrolase, family IA, variant 3
KEFONFAP_01412 1e-133 dedA S SNARE associated Golgi protein
KEFONFAP_01413 6e-122 cpaE D bacterial-type flagellum organization
KEFONFAP_01414 5.5e-189 cpaF U Type II IV secretion system protein
KEFONFAP_01415 9.8e-74 U Type ii secretion system
KEFONFAP_01416 5.8e-115 gspF NU Type II secretion system (T2SS), protein F
KEFONFAP_01417 1.1e-41 S Protein of unknown function (DUF4244)
KEFONFAP_01418 1.4e-57 U TadE-like protein
KEFONFAP_01419 6.5e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
KEFONFAP_01420 1.1e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
KEFONFAP_01421 3.5e-95 K Bacterial regulatory proteins, tetR family
KEFONFAP_01422 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
KEFONFAP_01423 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KEFONFAP_01424 8.6e-31 S ATPase domain predominantly from Archaea
KEFONFAP_01425 6.6e-197 3.4.22.70 M Sortase family
KEFONFAP_01426 4.8e-69 V Abi-like protein
KEFONFAP_01427 3.6e-193 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KEFONFAP_01428 1.3e-134 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
KEFONFAP_01429 1.8e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
KEFONFAP_01430 2.9e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KEFONFAP_01431 2.5e-112
KEFONFAP_01432 1.5e-174 L Domain of unknown function (DUF4862)
KEFONFAP_01433 4.1e-168 2.7.1.2 GK ROK family
KEFONFAP_01434 1.3e-125 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KEFONFAP_01435 3.6e-159 3.5.1.106 I carboxylic ester hydrolase activity
KEFONFAP_01436 3.1e-300 E Bacterial extracellular solute-binding proteins, family 5 Middle
KEFONFAP_01437 4.6e-153 oppB6 EP Binding-protein-dependent transport system inner membrane component
KEFONFAP_01438 0.0 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
KEFONFAP_01439 6.5e-148 oppF E ATPases associated with a variety of cellular activities
KEFONFAP_01440 9.8e-180 nanL 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
KEFONFAP_01441 4.6e-146 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KEFONFAP_01442 3.5e-13 nagA 3.5.1.25 G Amidohydrolase family
KEFONFAP_01443 0.0 nanI 3.2.1.18 GH33 G BNR repeat-like domain
KEFONFAP_01444 1.2e-246 P Domain of unknown function (DUF4143)
KEFONFAP_01445 9e-153 K FCD
KEFONFAP_01446 8.8e-273 S Calcineurin-like phosphoesterase
KEFONFAP_01447 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KEFONFAP_01448 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
KEFONFAP_01449 1.6e-165 3.6.1.27 I PAP2 superfamily
KEFONFAP_01450 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KEFONFAP_01451 4.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KEFONFAP_01452 3.9e-207 holB 2.7.7.7 L DNA polymerase III
KEFONFAP_01453 3e-105 K helix_turn _helix lactose operon repressor
KEFONFAP_01454 3.3e-37 ptsH G PTS HPr component phosphorylation site
KEFONFAP_01455 3.9e-293 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KEFONFAP_01456 3.1e-104 S Phosphatidylethanolamine-binding protein
KEFONFAP_01457 2.7e-310 pepD E Peptidase family C69
KEFONFAP_01458 2.5e-286 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
KEFONFAP_01459 6.7e-62 S Macrophage migration inhibitory factor (MIF)
KEFONFAP_01460 8.4e-96 S GtrA-like protein
KEFONFAP_01461 4.8e-247 EGP Major facilitator Superfamily
KEFONFAP_01462 2.6e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
KEFONFAP_01463 6.3e-118
KEFONFAP_01464 1.4e-228 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KEFONFAP_01465 2.2e-145 S Protein of unknown function (DUF805)
KEFONFAP_01467 2.7e-293 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KEFONFAP_01470 2.7e-31 L Phage integrase, N-terminal SAM-like domain
KEFONFAP_01471 1.9e-22 L Phage integrase, N-terminal SAM-like domain
KEFONFAP_01473 0.0 efeU_1 P Iron permease FTR1 family
KEFONFAP_01474 1.6e-99 tpd P Fe2+ transport protein
KEFONFAP_01475 3.2e-231 S Predicted membrane protein (DUF2318)
KEFONFAP_01476 6.5e-227 macB_2 V ABC transporter permease
KEFONFAP_01477 2.1e-199 Z012_06715 V FtsX-like permease family
KEFONFAP_01478 1.7e-145 macB V ABC transporter, ATP-binding protein
KEFONFAP_01479 2.4e-61 S FMN_bind
KEFONFAP_01480 7.1e-101 K Psort location Cytoplasmic, score 8.87
KEFONFAP_01481 2.2e-304 pip S YhgE Pip domain protein
KEFONFAP_01482 0.0 pip S YhgE Pip domain protein
KEFONFAP_01483 5.1e-251 S Putative ABC-transporter type IV
KEFONFAP_01484 2.2e-271 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KEFONFAP_01485 8.1e-138 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
KEFONFAP_01486 1.4e-192 opcA G Glucose-6-phosphate dehydrogenase subunit
KEFONFAP_01487 5e-303 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KEFONFAP_01488 3.4e-290 3.5.2.6 V Beta-lactamase enzyme family
KEFONFAP_01490 5.1e-300 pepD E Peptidase family C69
KEFONFAP_01491 2.8e-196 XK27_01805 M Glycosyltransferase like family 2
KEFONFAP_01492 1.4e-150 icaR K Bacterial regulatory proteins, tetR family
KEFONFAP_01493 2.2e-171 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KEFONFAP_01494 1e-227 amt U Ammonium Transporter Family
KEFONFAP_01495 1e-54 glnB K Nitrogen regulatory protein P-II
KEFONFAP_01496 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
KEFONFAP_01497 1.3e-238 dinF V MatE
KEFONFAP_01498 3.1e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KEFONFAP_01499 1e-257 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
KEFONFAP_01500 3.5e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KEFONFAP_01501 5.5e-38 S granule-associated protein
KEFONFAP_01502 0.0 ubiB S ABC1 family
KEFONFAP_01503 3.5e-71 K Periplasmic binding protein domain
KEFONFAP_01504 1.2e-238 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
KEFONFAP_01505 4.5e-155 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KEFONFAP_01506 1.3e-187 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KEFONFAP_01507 2.1e-118 EGP Major Facilitator Superfamily
KEFONFAP_01508 5.5e-137 EGP Major Facilitator Superfamily
KEFONFAP_01510 1.9e-115 K WHG domain
KEFONFAP_01511 6.5e-111 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
KEFONFAP_01512 1.5e-61 L PFAM Integrase catalytic
KEFONFAP_01513 1.2e-168 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KEFONFAP_01514 1.5e-231 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
KEFONFAP_01515 6.4e-142 cobB2 K Sir2 family
KEFONFAP_01516 1.4e-20
KEFONFAP_01517 2.6e-11
KEFONFAP_01519 4.5e-161 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KEFONFAP_01520 1.9e-86 msrA 1.8.4.11, 1.8.4.12 O peptide-methionine (S)-S-oxide reductase activity
KEFONFAP_01521 0.0 E ABC transporter, substrate-binding protein, family 5
KEFONFAP_01522 4.5e-13 L Psort location Cytoplasmic, score 8.87
KEFONFAP_01523 9.2e-169 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KEFONFAP_01524 4.8e-45
KEFONFAP_01525 2.1e-151 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
KEFONFAP_01526 3.1e-33
KEFONFAP_01527 4.3e-166 yfiL V ATPases associated with a variety of cellular activities
KEFONFAP_01528 7.1e-128
KEFONFAP_01529 2e-22
KEFONFAP_01530 9.8e-296 L PFAM Integrase catalytic
KEFONFAP_01531 4.3e-171 G Acyltransferase family
KEFONFAP_01532 7.4e-259 EGP Transmembrane secretion effector
KEFONFAP_01533 8.6e-56 KLT Protein tyrosine kinase
KEFONFAP_01534 1e-87 L IstB-like ATP binding protein
KEFONFAP_01535 0.0 trxB2 1.8.1.9 C Thioredoxin domain
KEFONFAP_01536 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
KEFONFAP_01537 2.4e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KEFONFAP_01538 5.5e-206 S AAA ATPase domain
KEFONFAP_01539 5.7e-234 ytfL P Transporter associated domain
KEFONFAP_01540 1.2e-82 dps P Belongs to the Dps family
KEFONFAP_01541 6.7e-256 S Domain of unknown function (DUF4143)
KEFONFAP_01542 9.3e-121 S Protein of unknown function DUF45
KEFONFAP_01545 7.4e-17 S Domain of unknown function (DUF4143)
KEFONFAP_01546 5.3e-197 S Psort location CytoplasmicMembrane, score
KEFONFAP_01547 2.8e-257 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KEFONFAP_01548 5.2e-203 V VanZ like family
KEFONFAP_01549 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KEFONFAP_01550 1.4e-15 lacS G Psort location CytoplasmicMembrane, score 10.00
KEFONFAP_01551 4.5e-183 lacR K Transcriptional regulator, LacI family
KEFONFAP_01552 9.3e-50 S Transmembrane domain of unknown function (DUF3566)
KEFONFAP_01553 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KEFONFAP_01554 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KEFONFAP_01555 4.2e-83 S Protein of unknown function (DUF721)
KEFONFAP_01556 1.1e-201 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KEFONFAP_01557 5.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KEFONFAP_01558 3.3e-280 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KEFONFAP_01559 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KEFONFAP_01560 2.9e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KEFONFAP_01561 9.3e-181 yidC U Membrane protein insertase, YidC Oxa1 family
KEFONFAP_01562 3e-93 jag S Putative single-stranded nucleic acids-binding domain
KEFONFAP_01563 3.4e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KEFONFAP_01564 8.1e-174 parA D CobQ CobB MinD ParA nucleotide binding domain protein
KEFONFAP_01565 1e-221 parB K Belongs to the ParB family
KEFONFAP_01566 3.5e-175 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KEFONFAP_01567 0.0 murJ KLT MviN-like protein
KEFONFAP_01568 0.0
KEFONFAP_01569 2.3e-160 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
KEFONFAP_01570 2.7e-282 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
KEFONFAP_01571 3.1e-110 S LytR cell envelope-related transcriptional attenuator
KEFONFAP_01572 1.3e-173 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KEFONFAP_01573 2.2e-168 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KEFONFAP_01574 4.8e-215 S G5
KEFONFAP_01576 2e-135 O Thioredoxin
KEFONFAP_01577 0.0 KLT Protein tyrosine kinase
KEFONFAP_01578 3.9e-119 3.2.1.21 GH3 G Fibronectin type III-like domain
KEFONFAP_01579 2.7e-118 T LytTr DNA-binding domain
KEFONFAP_01580 1.7e-134 T GHKL domain
KEFONFAP_01581 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
KEFONFAP_01582 7.7e-50 kcsA U Ion channel
KEFONFAP_01583 3.8e-125 S Protein of unknown function (DUF3990)
KEFONFAP_01584 3.1e-121 K Helix-turn-helix XRE-family like proteins
KEFONFAP_01585 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
KEFONFAP_01586 8.3e-122 S Psort location CytoplasmicMembrane, score
KEFONFAP_01588 2e-42 nrdH O Glutaredoxin
KEFONFAP_01589 6e-88 nrdI F Probably involved in ribonucleotide reductase function
KEFONFAP_01590 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEFONFAP_01592 1.3e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEFONFAP_01593 1.2e-216 2.4.1.166 GT2 M Glycosyltransferase like family 2
KEFONFAP_01594 2.1e-73 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KEFONFAP_01595 1.1e-44 ulaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
KEFONFAP_01596 4.9e-241 ulaA 2.7.1.194 S PTS system sugar-specific permease component
KEFONFAP_01597 6e-137 K UTRA domain
KEFONFAP_01598 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
KEFONFAP_01599 2.7e-126 tnp3514b L Winged helix-turn helix
KEFONFAP_01601 2.2e-185
KEFONFAP_01602 3.8e-142 U Branched-chain amino acid transport system / permease component
KEFONFAP_01603 7.9e-179 3.6.3.17 G ATPases associated with a variety of cellular activities
KEFONFAP_01604 4.2e-146 G Periplasmic binding protein domain
KEFONFAP_01605 1.5e-131 K helix_turn _helix lactose operon repressor
KEFONFAP_01606 7.6e-18 tnp7109-21 L Integrase core domain
KEFONFAP_01607 1.3e-287 S LPXTG-motif cell wall anchor domain protein
KEFONFAP_01608 8.4e-261 M LPXTG-motif cell wall anchor domain protein
KEFONFAP_01609 8.5e-179 3.4.22.70 M Sortase family
KEFONFAP_01610 4.2e-136
KEFONFAP_01611 2.3e-270 KLT Domain of unknown function (DUF4032)
KEFONFAP_01612 4.2e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KEFONFAP_01613 1.8e-164 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
KEFONFAP_01614 6.4e-174 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEFONFAP_01615 7.4e-43
KEFONFAP_01616 7.7e-125 I alpha/beta hydrolase fold
KEFONFAP_01617 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
KEFONFAP_01618 8.6e-25
KEFONFAP_01619 1e-110 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
KEFONFAP_01620 1.1e-150
KEFONFAP_01621 1.1e-146 ypfH S Phospholipase/Carboxylesterase
KEFONFAP_01622 4.7e-119 S membrane transporter protein
KEFONFAP_01623 0.0 yjcE P Sodium/hydrogen exchanger family
KEFONFAP_01624 9.8e-79 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KEFONFAP_01625 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
KEFONFAP_01626 3.8e-229 nagC GK ROK family
KEFONFAP_01627 3.8e-243 msmE7 G Bacterial extracellular solute-binding protein
KEFONFAP_01628 4.7e-147 malC G Binding-protein-dependent transport system inner membrane component
KEFONFAP_01629 2.9e-154 G Binding-protein-dependent transport system inner membrane component
KEFONFAP_01630 1.4e-105 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KEFONFAP_01631 3e-228 2.7.7.7 L Transposase and inactivated derivatives
KEFONFAP_01632 5.7e-09 L Transposase and inactivated derivatives
KEFONFAP_01633 2.8e-72
KEFONFAP_01635 1.4e-64
KEFONFAP_01637 1.3e-76 rpoE4 K Sigma-70 region 2
KEFONFAP_01638 4.3e-16 S Psort location CytoplasmicMembrane, score
KEFONFAP_01639 2.5e-106 L Transposase and inactivated derivatives IS30 family
KEFONFAP_01640 3.6e-137 sigH K Belongs to the sigma-70 factor family. ECF subfamily
KEFONFAP_01641 5.6e-52
KEFONFAP_01642 1.1e-186 galM 5.1.3.3 G Aldose 1-epimerase
KEFONFAP_01643 2.1e-190 galM 5.1.3.3 G Aldose 1-epimerase
KEFONFAP_01644 7.5e-183 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KEFONFAP_01645 4.2e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KEFONFAP_01646 1.4e-195 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KEFONFAP_01647 1.6e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
KEFONFAP_01648 1.1e-11 S Spermine/spermidine synthase domain
KEFONFAP_01649 1.7e-113 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KEFONFAP_01650 6.2e-25 rpmI J Ribosomal protein L35
KEFONFAP_01651 2.1e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KEFONFAP_01652 1.5e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KEFONFAP_01653 7.6e-145 xerD D recombinase XerD
KEFONFAP_01654 1.4e-149 soj D CobQ CobB MinD ParA nucleotide binding domain protein
KEFONFAP_01655 2.4e-151 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KEFONFAP_01656 4.4e-116 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KEFONFAP_01657 1.8e-153 nrtR 3.6.1.55 F NUDIX hydrolase
KEFONFAP_01658 7e-250 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KEFONFAP_01659 2.8e-296 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KEFONFAP_01660 1.5e-161 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
KEFONFAP_01661 8.1e-238 iscS1 2.8.1.7 E Aminotransferase class-V
KEFONFAP_01662 4.5e-19 naiP U Sugar (and other) transporter
KEFONFAP_01663 0.0 V FtsX-like permease family
KEFONFAP_01664 1.1e-136 V ATPases associated with a variety of cellular activities
KEFONFAP_01665 2.6e-106 K Virulence activator alpha C-term
KEFONFAP_01666 0.0 typA T Elongation factor G C-terminus
KEFONFAP_01667 1.4e-77
KEFONFAP_01668 1.5e-188 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
KEFONFAP_01669 1.2e-188 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
KEFONFAP_01670 1.7e-41
KEFONFAP_01671 0.0 MV MacB-like periplasmic core domain
KEFONFAP_01672 4.9e-148 V ABC transporter, ATP-binding protein
KEFONFAP_01673 2.1e-188 xerC D Belongs to the 'phage' integrase family. XerC subfamily
KEFONFAP_01674 2.9e-309 E ABC transporter, substrate-binding protein, family 5
KEFONFAP_01675 8.9e-154 dppB EP Binding-protein-dependent transport system inner membrane component
KEFONFAP_01676 1.9e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
KEFONFAP_01677 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
KEFONFAP_01678 3.3e-171 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
KEFONFAP_01679 4e-145 S Protein of unknown function (DUF3710)
KEFONFAP_01680 3.8e-134 S Protein of unknown function (DUF3159)
KEFONFAP_01681 1.2e-241 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KEFONFAP_01682 1.4e-96
KEFONFAP_01683 0.0 ctpE P E1-E2 ATPase
KEFONFAP_01684 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KEFONFAP_01685 1.1e-118 E Psort location Cytoplasmic, score 8.87
KEFONFAP_01686 1.4e-81 K helix_turn_helix, Lux Regulon
KEFONFAP_01687 9.7e-136 ybhL S Belongs to the BI1 family
KEFONFAP_01688 3.1e-165 ydeD EG EamA-like transporter family
KEFONFAP_01689 6.9e-145 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
KEFONFAP_01690 1.3e-276 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KEFONFAP_01691 2.1e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KEFONFAP_01692 2.2e-151 fic D Fic/DOC family
KEFONFAP_01693 0.0 ftsK D FtsK SpoIIIE family protein
KEFONFAP_01694 3.5e-117 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KEFONFAP_01695 7.4e-95 cinA 3.5.1.42 S Belongs to the CinA family
KEFONFAP_01696 7.6e-78 K Helix-turn-helix XRE-family like proteins
KEFONFAP_01697 7e-39 S Protein of unknown function (DUF3046)
KEFONFAP_01698 1.1e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KEFONFAP_01699 1.1e-101 recX S Modulates RecA activity
KEFONFAP_01700 2.4e-113 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KEFONFAP_01701 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KEFONFAP_01702 6.7e-190 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KEFONFAP_01703 2e-118
KEFONFAP_01704 6.2e-131 plsC2 2.3.1.51 I Phosphate acyltransferases
KEFONFAP_01705 0.0 pknL 2.7.11.1 KLT PASTA
KEFONFAP_01706 2.1e-194 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
KEFONFAP_01707 3.2e-110
KEFONFAP_01708 1.4e-190 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KEFONFAP_01709 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
KEFONFAP_01710 2.2e-221 G Major Facilitator Superfamily
KEFONFAP_01711 8.3e-171 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KEFONFAP_01712 0.0 lhr L DEAD DEAH box helicase
KEFONFAP_01713 1.2e-48 K Psort location Cytoplasmic, score
KEFONFAP_01714 5.2e-43 K Psort location Cytoplasmic, score
KEFONFAP_01715 2.3e-42 K AraC-like ligand binding domain
KEFONFAP_01716 3.1e-104 G Bacterial extracellular solute-binding protein
KEFONFAP_01717 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
KEFONFAP_01718 1.5e-233 S Type I phosphodiesterase / nucleotide pyrophosphatase
KEFONFAP_01719 1.3e-148 S Protein of unknown function (DUF3071)
KEFONFAP_01720 1.4e-47 S Domain of unknown function (DUF4193)
KEFONFAP_01721 5.5e-83 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KEFONFAP_01722 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KEFONFAP_01723 1.6e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KEFONFAP_01724 2.3e-74
KEFONFAP_01726 6.3e-238 S HipA-like C-terminal domain
KEFONFAP_01727 5e-50 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KEFONFAP_01729 3.3e-26
KEFONFAP_01730 5.9e-143 fic D Fic/DOC family
KEFONFAP_01731 4.6e-67 L Integrase core domain
KEFONFAP_01732 1.2e-47 L Integrase core domain
KEFONFAP_01733 7.1e-50 EGP Transmembrane secretion effector
KEFONFAP_01734 1.2e-243 bglA 3.2.1.21 G Glycosyl hydrolase family 1
KEFONFAP_01735 8e-160 U Binding-protein-dependent transport system inner membrane component
KEFONFAP_01736 2.7e-163 malC U Binding-protein-dependent transport system inner membrane component
KEFONFAP_01737 3.5e-241 malE G Bacterial extracellular solute-binding protein
KEFONFAP_01738 9e-217 rbsR K helix_turn _helix lactose operon repressor
KEFONFAP_01739 4.4e-21
KEFONFAP_01741 1.6e-60 S EamA-like transporter family
KEFONFAP_01742 2.5e-20 S EamA-like transporter family
KEFONFAP_01743 1.4e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KEFONFAP_01744 5.7e-222 dapC E Aminotransferase class I and II
KEFONFAP_01745 2.9e-59 fdxA C 4Fe-4S binding domain
KEFONFAP_01746 1.4e-268 E aromatic amino acid transport protein AroP K03293
KEFONFAP_01747 1.3e-213 murB 1.3.1.98 M Cell wall formation
KEFONFAP_01748 4.1e-25 rpmG J Ribosomal protein L33
KEFONFAP_01752 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KEFONFAP_01753 1.6e-134
KEFONFAP_01754 2.6e-85 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
KEFONFAP_01755 7.3e-56 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
KEFONFAP_01756 4.3e-31 fmdB S Putative regulatory protein
KEFONFAP_01757 7e-93 flgA NO SAF
KEFONFAP_01758 4.8e-28 L Superfamily I DNA and RNA helicases and helicase subunits
KEFONFAP_01759 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
KEFONFAP_01760 3.8e-185 T Forkhead associated domain
KEFONFAP_01761 9.3e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KEFONFAP_01762 2.4e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KEFONFAP_01763 6.4e-145 3.2.1.8 S alpha beta
KEFONFAP_01764 1.1e-251 pbuO S Permease family
KEFONFAP_01765 1.2e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KEFONFAP_01766 1.3e-171 pstA P Phosphate transport system permease
KEFONFAP_01767 1.2e-156 pstC P probably responsible for the translocation of the substrate across the membrane
KEFONFAP_01768 2.8e-202 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
KEFONFAP_01769 3.8e-142 KT Transcriptional regulatory protein, C terminal
KEFONFAP_01770 7.1e-205 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KEFONFAP_01771 9.7e-239 EGP Sugar (and other) transporter
KEFONFAP_01772 7.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KEFONFAP_01773 1.9e-236 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KEFONFAP_01774 4.1e-217 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KEFONFAP_01775 4.1e-86 ebgC G YhcH YjgK YiaL family protein
KEFONFAP_01776 0.0 ebgA 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KEFONFAP_01777 4.8e-114 pgmB 5.4.2.6 S phosphonoacetaldehyde hydrolase activity
KEFONFAP_01778 1.2e-155 EG EamA-like transporter family
KEFONFAP_01779 0.0 kojP 2.4.1.230 GH65 G Glycosyl hydrolase family 65 central catalytic domain
KEFONFAP_01780 5.7e-152 P Binding-protein-dependent transport system inner membrane component
KEFONFAP_01781 2.6e-169 malC U Binding-protein-dependent transport system inner membrane component
KEFONFAP_01782 3.1e-237 G Bacterial extracellular solute-binding protein
KEFONFAP_01783 4.6e-188 K Periplasmic binding protein domain
KEFONFAP_01784 6.8e-99 U MarC family integral membrane protein
KEFONFAP_01785 1.7e-262 pepC 3.4.22.40 E Peptidase C1-like family
KEFONFAP_01786 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
KEFONFAP_01787 8.9e-44 D nuclear chromosome segregation
KEFONFAP_01788 2.6e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KEFONFAP_01789 2.1e-149 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KEFONFAP_01790 1.3e-196 yfiH Q Multi-copper polyphenol oxidoreductase laccase
KEFONFAP_01791 4e-300 yegQ O Peptidase family U32 C-terminal domain
KEFONFAP_01792 5.3e-178 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KEFONFAP_01793 1.7e-102 rsmD 2.1.1.171 L Conserved hypothetical protein 95
KEFONFAP_01794 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
KEFONFAP_01795 2.5e-29 rpmB J Ribosomal L28 family
KEFONFAP_01796 7.4e-194 yegV G pfkB family carbohydrate kinase
KEFONFAP_01797 4.5e-236 yxiO S Vacuole effluxer Atg22 like
KEFONFAP_01798 2.5e-130 K helix_turn_helix, mercury resistance
KEFONFAP_01799 4.8e-63 T Toxic component of a toxin-antitoxin (TA) module
KEFONFAP_01800 1.8e-53 relB L RelB antitoxin
KEFONFAP_01801 2.3e-21 yxiO G Major facilitator Superfamily
KEFONFAP_01802 7.5e-181 K Helix-turn-helix XRE-family like proteins
KEFONFAP_01807 9.5e-46 XK27_04590 S NADPH-dependent FMN reductase
KEFONFAP_01808 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
KEFONFAP_01809 4.5e-294 pccB I Carboxyl transferase domain
KEFONFAP_01810 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
KEFONFAP_01812 1.2e-90 bioY S BioY family
KEFONFAP_01813 2.2e-163 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
KEFONFAP_01814 0.0
KEFONFAP_01815 3.2e-164 QT PucR C-terminal helix-turn-helix domain
KEFONFAP_01816 2.7e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KEFONFAP_01817 4e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KEFONFAP_01818 1.8e-40
KEFONFAP_01819 3.8e-278 pip S YhgE Pip domain protein
KEFONFAP_01820 0.0 pip S YhgE Pip domain protein
KEFONFAP_01821 5.7e-138 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
KEFONFAP_01822 1.2e-59 S Protein of unknown function (DUF4235)
KEFONFAP_01823 3.6e-102 G Phosphoglycerate mutase family
KEFONFAP_01824 2.9e-254 amyE G Bacterial extracellular solute-binding protein
KEFONFAP_01825 5.3e-184 K Psort location Cytoplasmic, score
KEFONFAP_01826 4.4e-147 malC G Binding-protein-dependent transport system inner membrane component
KEFONFAP_01827 6.8e-153 rafG G ABC transporter permease
KEFONFAP_01828 1.1e-104 S Protein of unknown function, DUF624
KEFONFAP_01829 3.8e-268 aroP E aromatic amino acid transport protein AroP K03293
KEFONFAP_01830 7.5e-129 V ABC transporter
KEFONFAP_01831 0.0 V FtsX-like permease family
KEFONFAP_01832 9.5e-278 cycA E Amino acid permease
KEFONFAP_01833 1.2e-91 ydgJ K helix_turn_helix multiple antibiotic resistance protein
KEFONFAP_01834 0.0 lmrA1 V ABC transporter, ATP-binding protein
KEFONFAP_01835 0.0 lmrA2 V ABC transporter transmembrane region
KEFONFAP_01836 8.1e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KEFONFAP_01837 1.1e-256 G MFS/sugar transport protein
KEFONFAP_01839 6.5e-182 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KEFONFAP_01840 9.4e-121
KEFONFAP_01841 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KEFONFAP_01842 2.5e-46
KEFONFAP_01843 1.2e-277 pepC 3.4.22.40 E Peptidase C1-like family
KEFONFAP_01844 1.8e-176 appB EP Binding-protein-dependent transport system inner membrane component
KEFONFAP_01845 3.2e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
KEFONFAP_01846 0.0 oppD P Belongs to the ABC transporter superfamily
KEFONFAP_01847 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
KEFONFAP_01848 4e-34 EGP Major facilitator Superfamily
KEFONFAP_01849 3.1e-54 EGP Major facilitator Superfamily
KEFONFAP_01850 1.5e-266 S AAA domain
KEFONFAP_01851 0.0 lacZ 3.2.1.23 G Beta-galactosidase trimerisation domain
KEFONFAP_01852 8.1e-196 K helix_turn _helix lactose operon repressor
KEFONFAP_01853 1.8e-242 G Bacterial extracellular solute-binding protein
KEFONFAP_01854 1.3e-176 U Binding-protein-dependent transport system inner membrane component
KEFONFAP_01855 1.4e-153 U Binding-protein-dependent transport system inner membrane component
KEFONFAP_01856 3.7e-192 G Glycosyl hydrolases family 43
KEFONFAP_01857 1.2e-252 S Domain of unknown function (DUF4143)
KEFONFAP_01858 8.7e-270 S ATPase domain predominantly from Archaea
KEFONFAP_01859 0.0 mdlA2 V ABC transporter
KEFONFAP_01860 0.0 yknV V ABC transporter
KEFONFAP_01861 2e-185 tatD L TatD related DNase
KEFONFAP_01862 0.0 kup P Transport of potassium into the cell
KEFONFAP_01863 1.8e-159 S Glutamine amidotransferase domain
KEFONFAP_01864 6e-140 T HD domain
KEFONFAP_01865 8.1e-184 V ABC transporter
KEFONFAP_01866 3.3e-256 V ABC transporter permease
KEFONFAP_01867 6.8e-230 K Cell envelope-related transcriptional attenuator domain
KEFONFAP_01868 1.7e-193 lytC 3.1.4.46, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
KEFONFAP_01869 5.6e-172 rfbJ M Glycosyl transferase family 2
KEFONFAP_01870 0.0
KEFONFAP_01871 1.2e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KEFONFAP_01872 1.9e-288 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KEFONFAP_01873 1.6e-171 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KEFONFAP_01874 5.8e-183 M Glycosyltransferase like family 2
KEFONFAP_01875 0.0 rgpF M Rhamnan synthesis protein F
KEFONFAP_01876 7.4e-144 rgpC U Transport permease protein
KEFONFAP_01877 1.8e-234 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
KEFONFAP_01878 2.1e-285 lsgC M transferase activity, transferring glycosyl groups
KEFONFAP_01879 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KEFONFAP_01880 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KEFONFAP_01883 2.1e-262 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
KEFONFAP_01884 1.2e-203 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
KEFONFAP_01885 2.3e-178 3.4.14.13 M Glycosyltransferase like family 2
KEFONFAP_01886 2.8e-272 S AI-2E family transporter
KEFONFAP_01887 2.3e-234 epsG M Glycosyl transferase family 21
KEFONFAP_01888 3.1e-190 natA V ATPases associated with a variety of cellular activities
KEFONFAP_01889 4e-298
KEFONFAP_01890 3.7e-250 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
KEFONFAP_01891 1.5e-206 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KEFONFAP_01892 2.7e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KEFONFAP_01893 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KEFONFAP_01895 5.8e-106 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
KEFONFAP_01896 1.3e-159 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KEFONFAP_01897 6.1e-263 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KEFONFAP_01898 2.5e-92 S Protein of unknown function (DUF3180)
KEFONFAP_01899 1.5e-169 tesB I Thioesterase-like superfamily
KEFONFAP_01900 0.0 yjjK S ATP-binding cassette protein, ChvD family
KEFONFAP_01901 2.8e-305 EGP Major Facilitator Superfamily
KEFONFAP_01903 1.5e-177 glkA 2.7.1.2 G ROK family
KEFONFAP_01904 3.4e-86 K Winged helix DNA-binding domain
KEFONFAP_01905 1.5e-18 lmrB U Major Facilitator Superfamily
KEFONFAP_01906 4.2e-166 dkgB S Oxidoreductase, aldo keto reductase family protein
KEFONFAP_01907 5e-72 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KEFONFAP_01908 2.4e-147
KEFONFAP_01909 3.2e-66 yebQ EGP Major facilitator Superfamily
KEFONFAP_01911 1.3e-36 rpmE J Binds the 23S rRNA
KEFONFAP_01912 4.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KEFONFAP_01913 6.5e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KEFONFAP_01914 2.6e-206 livK E Receptor family ligand binding region
KEFONFAP_01915 5.4e-111 U Belongs to the binding-protein-dependent transport system permease family
KEFONFAP_01916 1e-188 livM U Belongs to the binding-protein-dependent transport system permease family
KEFONFAP_01917 1.8e-161 E Branched-chain amino acid ATP-binding cassette transporter
KEFONFAP_01918 3.3e-124 livF E ATPases associated with a variety of cellular activities
KEFONFAP_01919 1.5e-118 ywlC 2.7.7.87 J Belongs to the SUA5 family
KEFONFAP_01920 2.1e-211 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
KEFONFAP_01921 4.8e-293 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KEFONFAP_01922 4.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
KEFONFAP_01923 4.1e-267 recD2 3.6.4.12 L PIF1-like helicase
KEFONFAP_01924 5.1e-258 S AMMECR1
KEFONFAP_01925 1.7e-200 pflA 1.97.1.4 O Radical SAM superfamily
KEFONFAP_01926 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KEFONFAP_01927 2.2e-117 L Single-strand binding protein family
KEFONFAP_01928 0.0 pepO 3.4.24.71 O Peptidase family M13
KEFONFAP_01929 1e-138 S Short repeat of unknown function (DUF308)
KEFONFAP_01930 6e-151 map 3.4.11.18 E Methionine aminopeptidase
KEFONFAP_01931 7.8e-249 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
KEFONFAP_01932 3.4e-146 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
KEFONFAP_01933 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
KEFONFAP_01934 4.5e-100 XK27_03610 K Acetyltransferase (GNAT) domain
KEFONFAP_01935 7.4e-88 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KEFONFAP_01936 6.5e-201 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
KEFONFAP_01937 1e-234 aspB E Aminotransferase class-V
KEFONFAP_01938 2.9e-179 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KEFONFAP_01939 1.6e-200 S Endonuclease/Exonuclease/phosphatase family
KEFONFAP_01941 1.4e-77 F Nucleoside 2-deoxyribosyltransferase
KEFONFAP_01942 8.8e-63 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KEFONFAP_01943 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KEFONFAP_01944 4.1e-95 ywrO 1.6.5.2 S Flavodoxin-like fold
KEFONFAP_01945 3.7e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KEFONFAP_01946 1.8e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KEFONFAP_01947 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
KEFONFAP_01948 7.7e-137 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KEFONFAP_01949 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
KEFONFAP_01950 2.1e-254 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
KEFONFAP_01951 2.1e-142 K Bacterial regulatory proteins, tetR family
KEFONFAP_01952 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
KEFONFAP_01954 1.6e-45 S Nucleotidyltransferase domain
KEFONFAP_01955 1.3e-69 S Nucleotidyltransferase substrate binding protein like
KEFONFAP_01956 1.6e-240 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
KEFONFAP_01957 2e-45 L IstB-like ATP binding protein
KEFONFAP_01958 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
KEFONFAP_01959 8e-174 3.4.22.70 M Sortase family
KEFONFAP_01960 0.0 M domain protein
KEFONFAP_01961 0.0 M cell wall anchor domain protein
KEFONFAP_01963 1.5e-186 K Psort location Cytoplasmic, score
KEFONFAP_01964 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
KEFONFAP_01965 3.7e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KEFONFAP_01966 2.4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KEFONFAP_01967 1.8e-251 yhjE EGP Sugar (and other) transporter
KEFONFAP_01968 3.7e-180 K helix_turn _helix lactose operon repressor
KEFONFAP_01969 1.7e-277 scrT G Transporter major facilitator family protein
KEFONFAP_01970 4.1e-297 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
KEFONFAP_01971 6e-202 K helix_turn _helix lactose operon repressor
KEFONFAP_01972 7.2e-51 natB E Receptor family ligand binding region
KEFONFAP_01973 8.7e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEFONFAP_01974 4.4e-141 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEFONFAP_01975 4.5e-280 clcA P Voltage gated chloride channel
KEFONFAP_01976 2e-244 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KEFONFAP_01977 2.4e-195 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
KEFONFAP_01978 1.2e-166 yicL EG EamA-like transporter family
KEFONFAP_01980 9.9e-169 htpX O Belongs to the peptidase M48B family
KEFONFAP_01981 1e-276 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
KEFONFAP_01982 0.0 cadA P E1-E2 ATPase
KEFONFAP_01983 1.4e-228 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
KEFONFAP_01984 1e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KEFONFAP_01986 8.3e-146 yplQ S Haemolysin-III related
KEFONFAP_01987 3.7e-88 yjcF Q Acetyltransferase (GNAT) domain
KEFONFAP_01988 3.5e-52 ybjQ S Putative heavy-metal-binding
KEFONFAP_01989 3.4e-166 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KEFONFAP_01990 3e-125 S Domain of unknown function (DUF4928)
KEFONFAP_01991 1.2e-173 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
KEFONFAP_01992 2.1e-259 L Z1 domain
KEFONFAP_01993 3.4e-32 S Putative PD-(D/E)XK family member, (DUF4420)
KEFONFAP_01994 1e-32 S Putative PD-(D/E)XK family member, (DUF4420)
KEFONFAP_01995 2.3e-241 S AIPR protein
KEFONFAP_01996 1e-175 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KEFONFAP_01997 8.3e-164 M Glycosyltransferase like family 2
KEFONFAP_01998 8.8e-198 S Fic/DOC family
KEFONFAP_01999 1.1e-130 S Pyridoxamine 5'-phosphate oxidase
KEFONFAP_02000 6.9e-200 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KEFONFAP_02001 0.0 lysX S Uncharacterised conserved protein (DUF2156)
KEFONFAP_02002 4.3e-253 S Putative esterase
KEFONFAP_02003 7.1e-20
KEFONFAP_02004 7.2e-170 yddG EG EamA-like transporter family
KEFONFAP_02005 3.4e-91 hsp20 O Hsp20/alpha crystallin family
KEFONFAP_02006 2.9e-212 pldB 3.1.1.5 I Serine aminopeptidase, S33
KEFONFAP_02007 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
KEFONFAP_02008 2e-129 fhaA T Protein of unknown function (DUF2662)
KEFONFAP_02009 1e-74 fhaB T Inner membrane component of T3SS, cytoplasmic domain
KEFONFAP_02010 1.8e-271 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
KEFONFAP_02011 1e-277 rodA D Belongs to the SEDS family
KEFONFAP_02012 4.5e-261 pbpA M penicillin-binding protein
KEFONFAP_02013 1.3e-171 T Protein tyrosine kinase
KEFONFAP_02014 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
KEFONFAP_02015 2.9e-119 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
KEFONFAP_02016 3.8e-229 srtA 3.4.22.70 M Sortase family
KEFONFAP_02017 1.8e-118 S Bacterial protein of unknown function (DUF881)
KEFONFAP_02018 7.5e-69 crgA D Involved in cell division
KEFONFAP_02019 3e-120 gluP 3.4.21.105 S Rhomboid family
KEFONFAP_02020 4.5e-35
KEFONFAP_02021 9.6e-45 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)