ORF_ID e_value Gene_name EC_number CAZy COGs Description
GPELGMEL_00001 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
GPELGMEL_00002 3.1e-304 trxB1 1.8.1.9 C Thioredoxin domain
GPELGMEL_00003 1.2e-228 yhjX EGP Major facilitator Superfamily
GPELGMEL_00004 1.1e-28 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
GPELGMEL_00005 6.8e-31 lacS G Psort location CytoplasmicMembrane, score 10.00
GPELGMEL_00006 1.8e-240 vex3 V ABC transporter permease
GPELGMEL_00007 4.5e-214 vex1 V Efflux ABC transporter, permease protein
GPELGMEL_00008 4e-113 vex2 V ABC transporter, ATP-binding protein
GPELGMEL_00009 1.8e-80 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
GPELGMEL_00010 3.2e-113 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
GPELGMEL_00011 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
GPELGMEL_00012 1.3e-72 S GtrA-like protein
GPELGMEL_00013 1.3e-10 S LPXTG-motif cell wall anchor domain protein
GPELGMEL_00014 0.0 S LPXTG-motif cell wall anchor domain protein
GPELGMEL_00015 4.7e-235 M LPXTG-motif cell wall anchor domain protein
GPELGMEL_00016 4.7e-145 3.4.22.70 M Sortase family
GPELGMEL_00017 2.4e-136
GPELGMEL_00018 8.8e-48 S Psort location Cytoplasmic, score
GPELGMEL_00019 1.6e-212 clcA_2 P Voltage gated chloride channel
GPELGMEL_00020 7.2e-57
GPELGMEL_00021 8.8e-233 T GHKL domain
GPELGMEL_00022 8.2e-131 K LytTr DNA-binding domain
GPELGMEL_00023 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
GPELGMEL_00024 2e-269 KLT Domain of unknown function (DUF4032)
GPELGMEL_00025 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPELGMEL_00026 1.1e-231 EGP Major facilitator Superfamily
GPELGMEL_00027 4.5e-13 S Psort location Extracellular, score 8.82
GPELGMEL_00028 3.4e-55 DJ Addiction module toxin, RelE StbE family
GPELGMEL_00029 2.3e-48 S Antitoxin component of a toxin-antitoxin (TA) module
GPELGMEL_00030 5.5e-116 S Short repeat of unknown function (DUF308)
GPELGMEL_00031 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
GPELGMEL_00032 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
GPELGMEL_00033 5.7e-85 K Cro/C1-type HTH DNA-binding domain
GPELGMEL_00034 1.2e-48 I alpha/beta hydrolase fold
GPELGMEL_00035 8.7e-102 I alpha/beta hydrolase fold
GPELGMEL_00036 2.8e-145 cobB2 K Sir2 family
GPELGMEL_00037 2.6e-233 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
GPELGMEL_00038 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
GPELGMEL_00039 2.6e-155 G Binding-protein-dependent transport system inner membrane component
GPELGMEL_00040 3.9e-157 G Binding-protein-dependent transport system inner membrane component
GPELGMEL_00041 1.5e-244 msmE7 G Bacterial extracellular solute-binding protein
GPELGMEL_00042 1.5e-230 nagC GK ROK family
GPELGMEL_00043 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
GPELGMEL_00044 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GPELGMEL_00045 0.0 yjcE P Sodium/hydrogen exchanger family
GPELGMEL_00046 2.7e-154 ypfH S Phospholipase/Carboxylesterase
GPELGMEL_00047 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
GPELGMEL_00048 1.3e-47 L PFAM Integrase catalytic
GPELGMEL_00049 2.3e-37 yxeN P amino acid ABC transporter
GPELGMEL_00050 4.3e-36 E Binding-protein-dependent transport system inner membrane component
GPELGMEL_00051 6.2e-73 3.6.3.21 E ABC transporter
GPELGMEL_00052 3e-68 odh 1.5.1.28 I glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GPELGMEL_00053 2.3e-18 ET Bacterial periplasmic substrate-binding proteins
GPELGMEL_00055 5.6e-238 bglA 3.2.1.21 G Glycosyl hydrolase family 1
GPELGMEL_00056 8.7e-159 U Binding-protein-dependent transport system inner membrane component
GPELGMEL_00057 1e-162 U Binding-protein-dependent transport system inner membrane component
GPELGMEL_00058 1.6e-238 malE G Bacterial extracellular solute-binding protein
GPELGMEL_00059 1.8e-201 rbsR K helix_turn _helix lactose operon repressor
GPELGMEL_00060 1.4e-41 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
GPELGMEL_00061 7.8e-224 C Polysaccharide pyruvyl transferase
GPELGMEL_00062 5.5e-211 GT2 M Glycosyltransferase like family 2
GPELGMEL_00063 7.1e-192 1.13.11.79 C Psort location Cytoplasmic, score 8.87
GPELGMEL_00064 1.1e-183 wbbI M transferase activity, transferring glycosyl groups
GPELGMEL_00065 7.2e-189 S Endonuclease/Exonuclease/phosphatase family
GPELGMEL_00066 2.5e-47
GPELGMEL_00067 4.7e-285 EGP Major facilitator Superfamily
GPELGMEL_00068 3.2e-217 T Diguanylate cyclase (GGDEF) domain protein
GPELGMEL_00069 6.2e-127 L Protein of unknown function (DUF1524)
GPELGMEL_00070 4.2e-166 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
GPELGMEL_00071 2.1e-241 mntH P H( )-stimulated, divalent metal cation uptake system
GPELGMEL_00072 2.2e-196 K helix_turn _helix lactose operon repressor
GPELGMEL_00073 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
GPELGMEL_00074 9.1e-168 G ABC transporter permease
GPELGMEL_00075 3.3e-147 G Binding-protein-dependent transport system inner membrane component
GPELGMEL_00076 3.2e-189 K Periplasmic binding protein domain
GPELGMEL_00077 3.4e-228 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GPELGMEL_00078 9.8e-143 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
GPELGMEL_00079 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GPELGMEL_00080 8.5e-145 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
GPELGMEL_00081 2.2e-142 yecS E Binding-protein-dependent transport system inner membrane component
GPELGMEL_00082 2.6e-137 pknD ET ABC transporter, substrate-binding protein, family 3
GPELGMEL_00083 1e-35 pknD ET ABC transporter, substrate-binding protein, family 3
GPELGMEL_00084 4.4e-156 pknD ET ABC transporter, substrate-binding protein, family 3
GPELGMEL_00085 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GPELGMEL_00086 2.9e-148 usp 3.5.1.28 CBM50 D CHAP domain protein
GPELGMEL_00087 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
GPELGMEL_00088 1.2e-167 ftsE D Cell division ATP-binding protein FtsE
GPELGMEL_00089 1.1e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GPELGMEL_00090 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPELGMEL_00091 4.9e-142 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
GPELGMEL_00092 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
GPELGMEL_00093 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
GPELGMEL_00094 0.0 pepO 3.4.24.71 O Peptidase family M13
GPELGMEL_00095 1.5e-97 L Single-strand binding protein family
GPELGMEL_00096 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GPELGMEL_00097 7.9e-271 recD2 3.6.4.12 L PIF1-like helicase
GPELGMEL_00098 4.5e-163 supH S Sucrose-6F-phosphate phosphohydrolase
GPELGMEL_00099 8.2e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
GPELGMEL_00100 2.7e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GPELGMEL_00101 4.5e-195 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
GPELGMEL_00102 9.9e-115 ywlC 2.7.7.87 J Belongs to the SUA5 family
GPELGMEL_00103 1.9e-124 livF E ATPases associated with a variety of cellular activities
GPELGMEL_00104 4.8e-151 E Branched-chain amino acid ATP-binding cassette transporter
GPELGMEL_00105 6.7e-196 livM U Belongs to the binding-protein-dependent transport system permease family
GPELGMEL_00106 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
GPELGMEL_00107 2.7e-219 livK E Receptor family ligand binding region
GPELGMEL_00108 9.4e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GPELGMEL_00109 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPELGMEL_00110 1.5e-35 rpmE J Binds the 23S rRNA
GPELGMEL_00112 5.7e-225 xylR GK ROK family
GPELGMEL_00113 2.9e-287 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
GPELGMEL_00114 2.1e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
GPELGMEL_00115 9.7e-09 CE10 I Belongs to the type-B carboxylesterase lipase family
GPELGMEL_00116 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
GPELGMEL_00117 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
GPELGMEL_00118 2.4e-164 MA20_14020 P Binding-protein-dependent transport system inner membrane component
GPELGMEL_00119 1.5e-186 MA20_14025 U Binding-protein-dependent transport system inner membrane component
GPELGMEL_00120 1.2e-151 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
GPELGMEL_00121 1.8e-79 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
GPELGMEL_00122 7.2e-189 K Bacterial regulatory proteins, lacI family
GPELGMEL_00123 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
GPELGMEL_00124 6.6e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
GPELGMEL_00125 1.3e-248 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
GPELGMEL_00126 3.6e-266 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
GPELGMEL_00127 4.5e-107 S Membrane
GPELGMEL_00128 1.1e-133 ydcZ S Putative inner membrane exporter, YdcZ
GPELGMEL_00129 3.6e-61 ykoE S ABC-type cobalt transport system, permease component
GPELGMEL_00130 2.3e-226 xylR GK ROK family
GPELGMEL_00131 3.4e-291 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
GPELGMEL_00132 2.1e-168 F Inosine-uridine preferring nucleoside hydrolase
GPELGMEL_00133 1.1e-214 bdhA C Iron-containing alcohol dehydrogenase
GPELGMEL_00134 8.6e-09 bdhA C Iron-containing alcohol dehydrogenase
GPELGMEL_00135 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
GPELGMEL_00136 6.2e-234 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
GPELGMEL_00137 0.0 O Highly conserved protein containing a thioredoxin domain
GPELGMEL_00138 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
GPELGMEL_00139 0.0 G Psort location Cytoplasmic, score 8.87
GPELGMEL_00140 4.3e-150 G Binding-protein-dependent transport system inner membrane component
GPELGMEL_00141 2.1e-174 U Binding-protein-dependent transport system inner membrane component
GPELGMEL_00142 3.5e-232 G ABC transporter periplasmic binding protein YcjN precursor K02027
GPELGMEL_00143 1.4e-16 G ABC transporter periplasmic binding protein YcjN precursor K02027
GPELGMEL_00144 2.3e-98 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
GPELGMEL_00145 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GPELGMEL_00146 1.1e-180 V Beta-lactamase
GPELGMEL_00147 0.0 yjjK S ATP-binding cassette protein, ChvD family
GPELGMEL_00148 8.5e-165 tesB I Thioesterase-like superfamily
GPELGMEL_00149 3.1e-93 S Protein of unknown function (DUF3180)
GPELGMEL_00150 7e-273 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPELGMEL_00151 1.5e-155 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPELGMEL_00152 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
GPELGMEL_00153 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPELGMEL_00154 1.1e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GPELGMEL_00155 2e-200 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GPELGMEL_00156 1.1e-232 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
GPELGMEL_00157 6.3e-232 epsG M Glycosyl transferase family 21
GPELGMEL_00158 1.3e-237 S AI-2E family transporter
GPELGMEL_00159 5.5e-180 3.4.14.13 M Glycosyltransferase like family 2
GPELGMEL_00160 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
GPELGMEL_00161 0.0 yliE T Putative diguanylate phosphodiesterase
GPELGMEL_00162 2.2e-111 S Domain of unknown function (DUF4956)
GPELGMEL_00163 1.4e-158 P VTC domain
GPELGMEL_00164 6.5e-310 cotH M CotH kinase protein
GPELGMEL_00165 3.4e-283 pelG S Putative exopolysaccharide Exporter (EPS-E)
GPELGMEL_00166 1.6e-282 pelF GT4 M Domain of unknown function (DUF3492)
GPELGMEL_00167 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
GPELGMEL_00168 3e-154
GPELGMEL_00169 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
GPELGMEL_00173 2.7e-163 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GPELGMEL_00174 7.6e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GPELGMEL_00176 3.6e-85 ptpA 3.1.3.48 T low molecular weight
GPELGMEL_00177 6.4e-130 folA 1.5.1.3 H dihydrofolate reductase
GPELGMEL_00178 1.9e-180 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPELGMEL_00179 1e-72 attW O OsmC-like protein
GPELGMEL_00180 1.3e-190 T Universal stress protein family
GPELGMEL_00181 1.3e-79 M NlpC/P60 family
GPELGMEL_00182 1.3e-165 usp 3.5.1.28 CBM50 S CHAP domain
GPELGMEL_00183 8.2e-218 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPELGMEL_00184 6.2e-41
GPELGMEL_00185 3.6e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
GPELGMEL_00186 3.3e-89 phoU P Plays a role in the regulation of phosphate uptake
GPELGMEL_00187 0.0 4.2.1.53 S MCRA family
GPELGMEL_00188 3e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GPELGMEL_00189 8.6e-207 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
GPELGMEL_00190 4.1e-99 S Serine aminopeptidase, S33
GPELGMEL_00191 8.8e-251 G Psort location CytoplasmicMembrane, score 10.00
GPELGMEL_00192 4.5e-194 K helix_turn _helix lactose operon repressor
GPELGMEL_00193 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GPELGMEL_00195 1.7e-213 araJ EGP Major facilitator Superfamily
GPELGMEL_00196 0.0 S Domain of unknown function (DUF4037)
GPELGMEL_00197 3.3e-115 S Protein of unknown function (DUF4125)
GPELGMEL_00198 2.7e-92
GPELGMEL_00199 2.9e-146 pspC KT PspC domain
GPELGMEL_00200 1.3e-264 tcsS3 KT PspC domain
GPELGMEL_00201 5.6e-121 degU K helix_turn_helix, Lux Regulon
GPELGMEL_00202 5.6e-141 yidP K UTRA
GPELGMEL_00203 5.3e-264 gabT 2.6.1.19, 2.6.1.22 H Aminotransferase class-III
GPELGMEL_00204 2.8e-274 eat E Amino acid permease
GPELGMEL_00205 1.5e-213 S Choline/ethanolamine kinase
GPELGMEL_00206 1.3e-102 Q Isochorismatase family
GPELGMEL_00207 1.1e-270 U Permease for cytosine/purines, uracil, thiamine, allantoin
GPELGMEL_00208 3.2e-189 yegV G pfkB family carbohydrate kinase
GPELGMEL_00209 6.7e-187 yegU O ADP-ribosylglycohydrolase
GPELGMEL_00211 1.3e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPELGMEL_00212 9.8e-200 I Diacylglycerol kinase catalytic domain
GPELGMEL_00213 2.8e-157 arbG K CAT RNA binding domain
GPELGMEL_00214 0.0 crr G pts system, glucose-specific IIABC component
GPELGMEL_00215 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
GPELGMEL_00216 2.8e-151 T LytTr DNA-binding domain
GPELGMEL_00217 1.5e-250 T GHKL domain
GPELGMEL_00218 4.3e-212 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPELGMEL_00219 2.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPELGMEL_00221 3.8e-108
GPELGMEL_00222 2.4e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPELGMEL_00223 1.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
GPELGMEL_00224 2.5e-187 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPELGMEL_00225 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPELGMEL_00226 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPELGMEL_00227 6.1e-191 nusA K Participates in both transcription termination and antitermination
GPELGMEL_00228 3.3e-78
GPELGMEL_00230 5.7e-183 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GPELGMEL_00231 1.3e-66 rplQ J Ribosomal protein L17
GPELGMEL_00232 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPELGMEL_00233 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPELGMEL_00234 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPELGMEL_00235 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GPELGMEL_00236 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPELGMEL_00237 2.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GPELGMEL_00238 3.8e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GPELGMEL_00239 2.2e-73 rplO J binds to the 23S rRNA
GPELGMEL_00240 3.4e-25 rpmD J Ribosomal protein L30p/L7e
GPELGMEL_00241 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPELGMEL_00242 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPELGMEL_00243 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPELGMEL_00244 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPELGMEL_00245 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPELGMEL_00246 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPELGMEL_00247 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPELGMEL_00248 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPELGMEL_00249 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPELGMEL_00250 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
GPELGMEL_00251 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPELGMEL_00252 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPELGMEL_00253 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPELGMEL_00254 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPELGMEL_00255 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPELGMEL_00256 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GPELGMEL_00257 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
GPELGMEL_00258 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPELGMEL_00259 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
GPELGMEL_00260 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GPELGMEL_00261 1.7e-179 rhaR_1 K helix_turn_helix, arabinose operon control protein
GPELGMEL_00262 9.5e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
GPELGMEL_00263 8e-238 EGP Major facilitator Superfamily
GPELGMEL_00264 2e-216 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
GPELGMEL_00265 1.4e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPELGMEL_00266 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
GPELGMEL_00267 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
GPELGMEL_00268 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPELGMEL_00269 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
GPELGMEL_00270 3.1e-122
GPELGMEL_00271 2.1e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
GPELGMEL_00272 9.4e-186 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPELGMEL_00273 2.1e-252 M Bacterial capsule synthesis protein PGA_cap
GPELGMEL_00274 4.4e-223 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPELGMEL_00276 1.4e-294 CE10 I Belongs to the type-B carboxylesterase lipase family
GPELGMEL_00277 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
GPELGMEL_00278 3.4e-232 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
GPELGMEL_00279 0.0 G Psort location Cytoplasmic, score 8.87
GPELGMEL_00280 3.1e-14 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
GPELGMEL_00281 4.3e-206 dapC E Aminotransferase class I and II
GPELGMEL_00282 8.3e-59 fdxA C 4Fe-4S binding domain
GPELGMEL_00283 2.8e-266 E aromatic amino acid transport protein AroP K03293
GPELGMEL_00284 5.4e-204 murB 1.3.1.98 M Cell wall formation
GPELGMEL_00285 5.5e-25 rpmG J Ribosomal protein L33
GPELGMEL_00289 5.7e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPELGMEL_00290 3e-146
GPELGMEL_00291 2.9e-122 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
GPELGMEL_00292 1.4e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
GPELGMEL_00293 6.1e-30 fmdB S Putative regulatory protein
GPELGMEL_00294 1.9e-92 flgA NO SAF
GPELGMEL_00295 7e-35
GPELGMEL_00296 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
GPELGMEL_00297 3.9e-177 T Forkhead associated domain
GPELGMEL_00298 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GPELGMEL_00299 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPELGMEL_00300 1.3e-246 pbuO S Permease family
GPELGMEL_00301 1.8e-143 P Zinc-uptake complex component A periplasmic
GPELGMEL_00302 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPELGMEL_00303 4e-168 pstA P Phosphate transport system permease
GPELGMEL_00304 3.4e-164 pstC P probably responsible for the translocation of the substrate across the membrane
GPELGMEL_00305 1.6e-197 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
GPELGMEL_00306 3.4e-129 KT Transcriptional regulatory protein, C terminal
GPELGMEL_00307 2.8e-220 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
GPELGMEL_00308 4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPELGMEL_00309 1.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPELGMEL_00310 9.7e-211 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GPELGMEL_00311 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
GPELGMEL_00312 1.3e-58 D nuclear chromosome segregation
GPELGMEL_00313 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GPELGMEL_00314 2.1e-143 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GPELGMEL_00315 4.1e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
GPELGMEL_00316 7e-297 yegQ O Peptidase family U32 C-terminal domain
GPELGMEL_00317 8.3e-170 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
GPELGMEL_00318 0.0 S Predicted membrane protein (DUF2207)
GPELGMEL_00319 1.7e-91 lemA S LemA family
GPELGMEL_00320 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GPELGMEL_00321 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPELGMEL_00322 1.6e-115
GPELGMEL_00324 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
GPELGMEL_00325 1.2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GPELGMEL_00327 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
GPELGMEL_00328 9.2e-311 pccB I Carboxyl transferase domain
GPELGMEL_00329 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
GPELGMEL_00330 4.6e-79 bioY S BioY family
GPELGMEL_00331 1.5e-161 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
GPELGMEL_00332 0.0
GPELGMEL_00333 5.9e-143 QT PucR C-terminal helix-turn-helix domain
GPELGMEL_00334 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GPELGMEL_00335 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPELGMEL_00336 2.9e-129 nusG K Participates in transcription elongation, termination and antitermination
GPELGMEL_00337 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GPELGMEL_00339 2.2e-232 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
GPELGMEL_00340 1.1e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPELGMEL_00341 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPELGMEL_00342 2.6e-39 rpmA J Ribosomal L27 protein
GPELGMEL_00343 7e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
GPELGMEL_00344 4.3e-308 rne 3.1.26.12 J Ribonuclease E/G family
GPELGMEL_00345 3.1e-231 dapE 3.5.1.18 E Peptidase dimerisation domain
GPELGMEL_00346 6.1e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
GPELGMEL_00347 2.5e-270 V Efflux ABC transporter, permease protein
GPELGMEL_00348 5e-128 V ATPases associated with a variety of cellular activities
GPELGMEL_00349 6.6e-119 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPELGMEL_00350 2e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GPELGMEL_00351 1.5e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GPELGMEL_00352 0.0 pgi 5.3.1.9 G Belongs to the GPI family
GPELGMEL_00353 5.4e-181 S Auxin Efflux Carrier
GPELGMEL_00356 1.8e-221 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
GPELGMEL_00357 1.1e-242 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
GPELGMEL_00358 1.1e-250 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPELGMEL_00359 1e-139 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPELGMEL_00360 1.2e-120 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPELGMEL_00361 1.1e-77 soxR K MerR, DNA binding
GPELGMEL_00362 4.6e-196 yghZ C Aldo/keto reductase family
GPELGMEL_00363 7.2e-58 S Protein of unknown function (DUF3039)
GPELGMEL_00364 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPELGMEL_00365 8.5e-134
GPELGMEL_00366 1.8e-113 yceD S Uncharacterized ACR, COG1399
GPELGMEL_00367 1e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GPELGMEL_00368 5.7e-136 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GPELGMEL_00369 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
GPELGMEL_00370 5.7e-92 ilvN 2.2.1.6 E ACT domain
GPELGMEL_00371 6.4e-96
GPELGMEL_00372 0.0 yjjK S ABC transporter
GPELGMEL_00373 1.9e-152 guaA1 6.3.5.2 F Peptidase C26
GPELGMEL_00374 9.3e-295 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPELGMEL_00375 2.7e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPELGMEL_00376 1.9e-176 S Endonuclease/Exonuclease/phosphatase family
GPELGMEL_00377 4.3e-53 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GPELGMEL_00378 1.8e-34 CP_0960 S Belongs to the UPF0109 family
GPELGMEL_00379 3.7e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPELGMEL_00380 1.5e-149 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GPELGMEL_00381 4.5e-98 rsmD 2.1.1.171 L Conserved hypothetical protein 95
GPELGMEL_00382 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
GPELGMEL_00383 8.4e-30 rpmB J Ribosomal L28 family
GPELGMEL_00384 0.0 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00385 4.6e-228 yxiO S Vacuole effluxer Atg22 like
GPELGMEL_00386 1.9e-127 gntR K FCD
GPELGMEL_00387 3.6e-78 gntK 2.7.1.12 F Shikimate kinase
GPELGMEL_00388 1.3e-227 gnuT EG GntP family permease
GPELGMEL_00390 5.2e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
GPELGMEL_00391 1.4e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
GPELGMEL_00392 6.3e-125 K Bacterial regulatory proteins, tetR family
GPELGMEL_00393 2.4e-228 MA20_36090 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00394 1.1e-228 MA20_36090 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00395 1.7e-137 M Mechanosensitive ion channel
GPELGMEL_00396 1.9e-179 S CAAX protease self-immunity
GPELGMEL_00397 9.8e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GPELGMEL_00398 1.7e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
GPELGMEL_00399 1.1e-174 plsC2 2.3.1.51 I Phosphate acyltransferases
GPELGMEL_00400 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPELGMEL_00401 3.6e-200 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
GPELGMEL_00402 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPELGMEL_00403 7.1e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPELGMEL_00404 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
GPELGMEL_00405 1.3e-279 S Calcineurin-like phosphoesterase
GPELGMEL_00408 5.5e-297 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPELGMEL_00409 4.1e-99 S Protein of unknown function (DUF805)
GPELGMEL_00410 7e-184
GPELGMEL_00411 1.5e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
GPELGMEL_00412 2.1e-263 EGP Major facilitator Superfamily
GPELGMEL_00413 7.1e-95 S GtrA-like protein
GPELGMEL_00414 6.7e-62 S Macrophage migration inhibitory factor (MIF)
GPELGMEL_00415 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
GPELGMEL_00416 0.0 pepD E Peptidase family C69
GPELGMEL_00417 2.4e-106 S Phosphatidylethanolamine-binding protein
GPELGMEL_00418 4.6e-286 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPELGMEL_00419 6e-39 ptsH G PTS HPr component phosphorylation site
GPELGMEL_00420 4.9e-185 K helix_turn _helix lactose operon repressor
GPELGMEL_00421 2.1e-192 holB 2.7.7.7 L DNA polymerase III
GPELGMEL_00422 4.7e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPELGMEL_00423 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPELGMEL_00424 8.1e-191 3.6.1.27 I PAP2 superfamily
GPELGMEL_00425 5.9e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
GPELGMEL_00426 2.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
GPELGMEL_00427 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
GPELGMEL_00429 0.0 S Beta-L-arabinofuranosidase, GH127
GPELGMEL_00430 1.9e-156 U Binding-protein-dependent transport system inner membrane component
GPELGMEL_00431 9.1e-170 G Binding-protein-dependent transport system inner membrane component
GPELGMEL_00432 4.8e-246 G Bacterial extracellular solute-binding protein
GPELGMEL_00433 3.5e-204 abf G Glycosyl hydrolases family 43
GPELGMEL_00434 1.1e-195 K helix_turn _helix lactose operon repressor
GPELGMEL_00435 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
GPELGMEL_00436 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
GPELGMEL_00437 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
GPELGMEL_00438 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPELGMEL_00439 8.4e-301 S Calcineurin-like phosphoesterase
GPELGMEL_00440 2.4e-115
GPELGMEL_00441 3.8e-40
GPELGMEL_00442 4.1e-38 K helix_turn_helix, Lux Regulon
GPELGMEL_00443 6.7e-07 2.7.13.3 T Histidine kinase
GPELGMEL_00444 1.3e-23 S Protein of unknown function (DUF1778)
GPELGMEL_00445 5.9e-46 K Acetyltransferase (GNAT) family
GPELGMEL_00446 9.2e-160 K Periplasmic binding protein domain
GPELGMEL_00447 1e-126 G Binding-protein-dependent transport system inner membrane component
GPELGMEL_00448 5.7e-156 malC G Binding-protein-dependent transport system inner membrane component
GPELGMEL_00449 4.1e-232 G Bacterial extracellular solute-binding protein
GPELGMEL_00450 1.9e-271 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
GPELGMEL_00451 0.0 3.2.1.22 G lipolytic protein G-D-S-L family
GPELGMEL_00452 8e-73 S Domain of unknown function (DUF4143)
GPELGMEL_00453 1.8e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPELGMEL_00454 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
GPELGMEL_00455 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
GPELGMEL_00456 7.7e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPELGMEL_00457 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
GPELGMEL_00458 1.1e-96 K Bacterial regulatory proteins, tetR family
GPELGMEL_00459 1.6e-193 S Psort location CytoplasmicMembrane, score
GPELGMEL_00460 1.9e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
GPELGMEL_00461 4.7e-56 S TIGRFAM helicase secretion neighborhood TadE-like protein
GPELGMEL_00462 5.1e-60 U TadE-like protein
GPELGMEL_00463 1.3e-42 S Protein of unknown function (DUF4244)
GPELGMEL_00464 2.2e-88 gspF NU Type II secretion system (T2SS), protein F
GPELGMEL_00465 6.9e-125 U Type ii secretion system
GPELGMEL_00466 6.1e-185 cpaF U Type II IV secretion system protein
GPELGMEL_00467 5.5e-141 cpaE D bacterial-type flagellum organization
GPELGMEL_00469 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GPELGMEL_00470 1.3e-209 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
GPELGMEL_00471 6.6e-91
GPELGMEL_00472 2.7e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPELGMEL_00473 9.4e-208 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
GPELGMEL_00474 0.0 G Bacterial Ig-like domain (group 4)
GPELGMEL_00475 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
GPELGMEL_00476 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
GPELGMEL_00477 9.3e-147 G Binding-protein-dependent transport system inner membrane component
GPELGMEL_00478 3.1e-167 P Binding-protein-dependent transport system inner membrane component
GPELGMEL_00479 4.3e-07 P Binding-protein-dependent transport system inner membrane component
GPELGMEL_00480 1.1e-242 G Bacterial extracellular solute-binding protein
GPELGMEL_00481 4.1e-192 K Periplasmic binding protein domain
GPELGMEL_00482 0.0 ubiB S ABC1 family
GPELGMEL_00483 1e-27 S granule-associated protein
GPELGMEL_00484 2.1e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
GPELGMEL_00485 2.8e-250 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
GPELGMEL_00486 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GPELGMEL_00487 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
GPELGMEL_00488 1e-54 glnB K Nitrogen regulatory protein P-II
GPELGMEL_00489 1.2e-236 amt U Ammonium Transporter Family
GPELGMEL_00490 1.5e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPELGMEL_00491 4.2e-107 icaR K Bacterial regulatory proteins, tetR family
GPELGMEL_00492 4e-195 XK27_01805 M Glycosyltransferase like family 2
GPELGMEL_00493 2.1e-307 pepD E Peptidase family C69
GPELGMEL_00495 3.1e-152 M cell wall binding repeat
GPELGMEL_00496 6e-38 nrdH O Glutaredoxin
GPELGMEL_00497 4.5e-225 S Putative ABC-transporter type IV
GPELGMEL_00498 0.0 pip S YhgE Pip domain protein
GPELGMEL_00499 1.8e-274 pip S YhgE Pip domain protein
GPELGMEL_00500 5.4e-89 K Psort location Cytoplasmic, score 8.87
GPELGMEL_00501 1.1e-61 S FMN_bind
GPELGMEL_00502 2.2e-148 macB V ABC transporter, ATP-binding protein
GPELGMEL_00503 5.4e-202 Z012_06715 V FtsX-like permease family
GPELGMEL_00505 2.3e-219 macB_2 V ABC transporter permease
GPELGMEL_00506 1.2e-230 S Predicted membrane protein (DUF2318)
GPELGMEL_00507 1.4e-92 tpd P Fe2+ transport protein
GPELGMEL_00508 1.7e-294 efeU_1 P Iron permease FTR1 family
GPELGMEL_00509 2e-237 G MFS/sugar transport protein
GPELGMEL_00510 2.8e-118 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GPELGMEL_00511 0.0 lmrA2 V ABC transporter transmembrane region
GPELGMEL_00512 2.1e-285 lmrA1 V ABC transporter, ATP-binding protein
GPELGMEL_00513 1.9e-57 ydgJ K helix_turn_helix multiple antibiotic resistance protein
GPELGMEL_00514 1.8e-182 1.1.1.65 C Aldo/keto reductase family
GPELGMEL_00515 1.9e-26 thiS 2.8.1.10 H ThiS family
GPELGMEL_00516 3.8e-128 thiF 2.7.7.73, 2.7.7.80 H ThiF family
GPELGMEL_00517 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
GPELGMEL_00518 9.9e-275 cycA E Amino acid permease
GPELGMEL_00519 2.5e-89 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00520 6.1e-168 M LPXTG cell wall anchor motif
GPELGMEL_00521 0.0 inlJ M domain protein
GPELGMEL_00522 3.4e-173 3.4.22.70 M Sortase family
GPELGMEL_00523 1.3e-76 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00524 2.7e-229 P Sodium/hydrogen exchanger family
GPELGMEL_00525 0.0 V FtsX-like permease family
GPELGMEL_00526 4.1e-270 aroP E aromatic amino acid transport protein AroP K03293
GPELGMEL_00527 2.5e-189 K helix_turn _helix lactose operon repressor
GPELGMEL_00528 1.4e-38 G beta-mannosidase
GPELGMEL_00529 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
GPELGMEL_00530 4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPELGMEL_00531 1.8e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPELGMEL_00532 3.5e-252 yhjE EGP Sugar (and other) transporter
GPELGMEL_00533 2.8e-269 scrT G Transporter major facilitator family protein
GPELGMEL_00534 1.6e-149 amyC5 P Binding-protein-dependent transport system inner membrane component
GPELGMEL_00535 1.1e-161 amyD3 P Binding-protein-dependent transport system inner membrane component
GPELGMEL_00536 4.5e-220 G Bacterial extracellular solute-binding protein
GPELGMEL_00537 0.0 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
GPELGMEL_00538 1.5e-115 S Protein of unknown function, DUF624
GPELGMEL_00539 3.1e-297 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
GPELGMEL_00540 1.1e-195 K helix_turn _helix lactose operon repressor
GPELGMEL_00541 1.4e-29 E Receptor family ligand binding region
GPELGMEL_00542 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPELGMEL_00543 1.3e-147 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPELGMEL_00544 1.3e-57 clcA P Voltage gated chloride channel
GPELGMEL_00545 2.1e-107 L Transposase and inactivated derivatives
GPELGMEL_00546 3.8e-29 L transposase activity
GPELGMEL_00547 9.8e-155 clcA P Voltage gated chloride channel
GPELGMEL_00548 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPELGMEL_00549 3.2e-217 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
GPELGMEL_00550 0.0 pip S YhgE Pip domain protein
GPELGMEL_00551 0.0 pip S YhgE Pip domain protein
GPELGMEL_00552 1.8e-170 yddG EG EamA-like transporter family
GPELGMEL_00553 3.2e-65 K Helix-turn-helix XRE-family like proteins
GPELGMEL_00555 7.2e-163 htpX O Belongs to the peptidase M48B family
GPELGMEL_00556 3.1e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
GPELGMEL_00557 3.9e-187 ansA 3.5.1.1 EJ Asparaginase
GPELGMEL_00558 0.0 cadA P E1-E2 ATPase
GPELGMEL_00559 1.2e-285 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
GPELGMEL_00560 4.7e-268 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GPELGMEL_00562 7.9e-44 ydeP K HxlR-like helix-turn-helix
GPELGMEL_00563 5.4e-86 XK27_10430 S NAD(P)H-binding
GPELGMEL_00564 2.8e-158 yicL EG EamA-like transporter family
GPELGMEL_00565 6.6e-193 pldB 3.1.1.5 I Serine aminopeptidase, S33
GPELGMEL_00566 8.7e-20 K helix_turn_helix, Lux Regulon
GPELGMEL_00567 3.7e-76 K helix_turn_helix, Lux Regulon
GPELGMEL_00568 3.5e-225 2.7.13.3 T Histidine kinase
GPELGMEL_00569 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
GPELGMEL_00570 1.2e-131 fhaA T Protein of unknown function (DUF2662)
GPELGMEL_00571 9.6e-73 fhaB T Inner membrane component of T3SS, cytoplasmic domain
GPELGMEL_00572 6.8e-242 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
GPELGMEL_00573 1.7e-266 rodA D Belongs to the SEDS family
GPELGMEL_00574 1e-265 pbpA M penicillin-binding protein
GPELGMEL_00575 5.8e-177 T Protein tyrosine kinase
GPELGMEL_00576 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
GPELGMEL_00577 2.3e-116 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
GPELGMEL_00578 3.7e-207 srtA 3.4.22.70 M Sortase family
GPELGMEL_00579 6.8e-142 S Bacterial protein of unknown function (DUF881)
GPELGMEL_00580 3.1e-57 crgA D Involved in cell division
GPELGMEL_00581 3.6e-239 L ribosomal rna small subunit methyltransferase
GPELGMEL_00582 6.3e-148 gluP 3.4.21.105 S Rhomboid family
GPELGMEL_00583 5.8e-35
GPELGMEL_00584 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GPELGMEL_00585 1.7e-63 I Sterol carrier protein
GPELGMEL_00586 1.4e-41 S Protein of unknown function (DUF3073)
GPELGMEL_00587 2.2e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPELGMEL_00588 2.1e-299 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPELGMEL_00589 0.0 yjjP S Threonine/Serine exporter, ThrE
GPELGMEL_00590 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GPELGMEL_00591 1.1e-38
GPELGMEL_00592 5.3e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
GPELGMEL_00593 4e-240 ytfL P Transporter associated domain
GPELGMEL_00594 1e-187 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GPELGMEL_00595 3.1e-101 S Protein of unknown function DUF45
GPELGMEL_00599 6.5e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GPELGMEL_00600 1.2e-260 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
GPELGMEL_00601 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
GPELGMEL_00602 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPELGMEL_00603 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPELGMEL_00604 6.2e-90 S Protein of unknown function (DUF721)
GPELGMEL_00605 1.3e-235 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPELGMEL_00606 3.9e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GPELGMEL_00607 3.1e-306 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPELGMEL_00608 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GPELGMEL_00609 1.5e-43 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GPELGMEL_00610 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
GPELGMEL_00611 3.6e-91 jag S Putative single-stranded nucleic acids-binding domain
GPELGMEL_00612 1.7e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
GPELGMEL_00613 4.5e-172 parA D CobQ CobB MinD ParA nucleotide binding domain protein
GPELGMEL_00614 4.4e-202 parB K Belongs to the ParB family
GPELGMEL_00615 3.1e-181 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GPELGMEL_00616 7e-14 S Psort location Extracellular, score 8.82
GPELGMEL_00617 1.4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GPELGMEL_00618 1.2e-12 S Domain of unknown function (DUF4143)
GPELGMEL_00619 0.0 murJ KLT MviN-like protein
GPELGMEL_00620 1.9e-303 murJ KLT MviN-like protein
GPELGMEL_00621 0.0 M Conserved repeat domain
GPELGMEL_00622 1.8e-121 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
GPELGMEL_00623 1.6e-282 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
GPELGMEL_00624 2.6e-109 S LytR cell envelope-related transcriptional attenuator
GPELGMEL_00625 9.6e-169 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPELGMEL_00626 1e-165 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GPELGMEL_00627 4.7e-197 S G5
GPELGMEL_00629 7.5e-151 O Thioredoxin
GPELGMEL_00630 0.0 KLT Protein tyrosine kinase
GPELGMEL_00631 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
GPELGMEL_00632 2.5e-82 V Abi-like protein
GPELGMEL_00633 4.5e-107 XK26_04895
GPELGMEL_00634 0.0 KL Type III restriction enzyme res subunit
GPELGMEL_00635 1.7e-55 L Eco57I restriction-modification methylase
GPELGMEL_00636 1.6e-55 L Eco57I restriction-modification methylase
GPELGMEL_00637 1.9e-178 3.1.21.4 V Type III restriction enzyme res subunit
GPELGMEL_00639 5.8e-130 L AAA ATPase domain
GPELGMEL_00640 7.5e-107 V ATPases associated with a variety of cellular activities
GPELGMEL_00641 4.9e-186
GPELGMEL_00642 2e-104 K Cro/C1-type HTH DNA-binding domain
GPELGMEL_00644 8.1e-177 L Replication initiation factor
GPELGMEL_00645 1e-20 xis S Excisionase from transposon Tn916
GPELGMEL_00646 1.3e-170 L Phage integrase family
GPELGMEL_00647 2.8e-28
GPELGMEL_00649 9.9e-36
GPELGMEL_00650 3.6e-125 3.2.1.8 S alpha beta
GPELGMEL_00651 2.3e-84 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GPELGMEL_00652 1.3e-190 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
GPELGMEL_00653 1.3e-113 kcsA U Ion channel
GPELGMEL_00654 5.1e-39 pepC 3.4.22.40 E homocysteine catabolic process
GPELGMEL_00655 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
GPELGMEL_00656 1.5e-107 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GPELGMEL_00657 0.0 ecfA GP ABC transporter, ATP-binding protein
GPELGMEL_00658 2.4e-47 yhbY J CRS1_YhbY
GPELGMEL_00659 1.8e-144 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPELGMEL_00660 2.2e-201 S Glycosyltransferase, group 2 family protein
GPELGMEL_00661 1.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
GPELGMEL_00662 8.1e-221 E Aminotransferase class I and II
GPELGMEL_00663 5e-145 bioM P ATPases associated with a variety of cellular activities
GPELGMEL_00664 5.4e-62 2.8.2.22 S Arylsulfotransferase Ig-like domain
GPELGMEL_00665 6e-220 2.8.2.22 S Arylsulfotransferase Ig-like domain
GPELGMEL_00666 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPELGMEL_00667 0.0 S Tetratricopeptide repeat
GPELGMEL_00668 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPELGMEL_00669 8.2e-213 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
GPELGMEL_00670 2.2e-84 ykoE S ABC-type cobalt transport system, permease component
GPELGMEL_00671 2.3e-268 ykoD P ATPases associated with a variety of cellular activities
GPELGMEL_00672 3.1e-145 cbiQ P Cobalt transport protein
GPELGMEL_00673 2.3e-251 argE E Peptidase dimerisation domain
GPELGMEL_00674 3.6e-93 S Protein of unknown function (DUF3043)
GPELGMEL_00675 2.9e-247 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GPELGMEL_00676 8.6e-142 S Domain of unknown function (DUF4191)
GPELGMEL_00677 2.3e-281 glnA 6.3.1.2 E glutamine synthetase
GPELGMEL_00678 4e-42 V DNA modification
GPELGMEL_00679 8.3e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
GPELGMEL_00680 1.5e-17 L HNH endonuclease
GPELGMEL_00682 2.9e-17
GPELGMEL_00684 2.7e-94 yvdD 3.2.2.10 S Possible lysine decarboxylase
GPELGMEL_00686 5.9e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPELGMEL_00687 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
GPELGMEL_00688 4.9e-99
GPELGMEL_00689 4.5e-205 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPELGMEL_00690 6.7e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GPELGMEL_00691 2.8e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
GPELGMEL_00692 2.7e-241 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
GPELGMEL_00693 4.6e-185 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPELGMEL_00694 2.3e-82 argR K Regulates arginine biosynthesis genes
GPELGMEL_00695 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GPELGMEL_00696 1.3e-279 argH 4.3.2.1 E argininosuccinate lyase
GPELGMEL_00697 9.7e-94 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPELGMEL_00698 8.6e-137 S Putative ABC-transporter type IV
GPELGMEL_00699 0.0 S Protein of unknown function (DUF975)
GPELGMEL_00700 1.9e-250 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPELGMEL_00701 4.3e-149 L Tetratricopeptide repeat
GPELGMEL_00702 1.1e-192 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
GPELGMEL_00703 2.4e-133 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GPELGMEL_00704 3e-116 trkA P TrkA-N domain
GPELGMEL_00705 2.1e-266 trkB P Cation transport protein
GPELGMEL_00706 2e-177 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPELGMEL_00707 1.8e-261 recN L May be involved in recombinational repair of damaged DNA
GPELGMEL_00708 2.2e-122 S Haloacid dehalogenase-like hydrolase
GPELGMEL_00709 1.6e-118 S ABC-2 family transporter protein
GPELGMEL_00710 8.6e-173 V ATPases associated with a variety of cellular activities
GPELGMEL_00711 1.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
GPELGMEL_00712 1.1e-23 C Acetamidase/Formamidase family
GPELGMEL_00713 1.6e-44 L transposition
GPELGMEL_00714 0.0 S Histidine phosphatase superfamily (branch 2)
GPELGMEL_00715 5.1e-96 S Pyridoxamine 5'-phosphate oxidase
GPELGMEL_00716 8e-24 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00717 1.2e-91 bcp 1.11.1.15 O Redoxin
GPELGMEL_00718 7.4e-77 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPELGMEL_00719 1.2e-166 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPELGMEL_00720 6.9e-164 IQ Enoyl-(Acyl carrier protein) reductase
GPELGMEL_00721 1e-34
GPELGMEL_00722 1.1e-88
GPELGMEL_00723 6.3e-173 G Fic/DOC family
GPELGMEL_00724 6.2e-105 3.1.3.27 E haloacid dehalogenase-like hydrolase
GPELGMEL_00725 4.6e-233 EGP Major facilitator Superfamily
GPELGMEL_00726 2.3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
GPELGMEL_00727 1.9e-250 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPELGMEL_00728 6.5e-243 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPELGMEL_00729 9.4e-101
GPELGMEL_00730 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPELGMEL_00731 5e-190 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPELGMEL_00733 1.8e-121
GPELGMEL_00734 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
GPELGMEL_00735 1.1e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPELGMEL_00736 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
GPELGMEL_00737 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPELGMEL_00739 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GPELGMEL_00740 7.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GPELGMEL_00741 6.1e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
GPELGMEL_00742 3.2e-225 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GPELGMEL_00743 3e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GPELGMEL_00744 1.9e-71 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GPELGMEL_00745 7.1e-297 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPELGMEL_00746 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GPELGMEL_00747 1e-162 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GPELGMEL_00748 4.6e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPELGMEL_00749 4.2e-97 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
GPELGMEL_00750 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
GPELGMEL_00751 3.9e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
GPELGMEL_00752 1e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPELGMEL_00753 3.8e-171 S Bacterial protein of unknown function (DUF881)
GPELGMEL_00754 4.2e-45 sbp S Protein of unknown function (DUF1290)
GPELGMEL_00755 1.6e-141 S Bacterial protein of unknown function (DUF881)
GPELGMEL_00756 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPELGMEL_00757 3.5e-112 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
GPELGMEL_00758 5.2e-128 yebC K transcriptional regulatory protein
GPELGMEL_00759 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GPELGMEL_00760 1e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GPELGMEL_00761 5.6e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GPELGMEL_00762 1.8e-50 yajC U Preprotein translocase subunit
GPELGMEL_00763 1.8e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPELGMEL_00764 4.9e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
GPELGMEL_00765 2.6e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GPELGMEL_00766 1.8e-246
GPELGMEL_00767 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GPELGMEL_00768 8.2e-34
GPELGMEL_00769 5.8e-161 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
GPELGMEL_00770 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPELGMEL_00771 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
GPELGMEL_00772 1.1e-69
GPELGMEL_00774 9.2e-264 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
GPELGMEL_00775 0.0 pafB K WYL domain
GPELGMEL_00776 2.1e-54
GPELGMEL_00777 0.0 helY L DEAD DEAH box helicase
GPELGMEL_00778 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
GPELGMEL_00779 3e-141 pgp 3.1.3.18 S HAD-hyrolase-like
GPELGMEL_00780 4.6e-61
GPELGMEL_00781 9.7e-112 K helix_turn_helix, mercury resistance
GPELGMEL_00782 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
GPELGMEL_00783 5.4e-36
GPELGMEL_00784 2.5e-08
GPELGMEL_00791 2.8e-156 S PAC2 family
GPELGMEL_00792 6.9e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GPELGMEL_00793 5.1e-158 G Fructosamine kinase
GPELGMEL_00794 9.9e-187 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GPELGMEL_00795 4.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GPELGMEL_00796 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
GPELGMEL_00797 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPELGMEL_00798 2.2e-41 nadR H ATPase kinase involved in NAD metabolism
GPELGMEL_00799 2.5e-49 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H ATPase kinase involved in NAD metabolism
GPELGMEL_00800 1.3e-113 pnuC H Nicotinamide mononucleotide transporter
GPELGMEL_00801 7.1e-09 pnuC H Nicotinamide mononucleotide transporter
GPELGMEL_00802 8e-301 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
GPELGMEL_00803 2.6e-177 S Sucrose-6F-phosphate phosphohydrolase
GPELGMEL_00804 2.4e-32 secG U Preprotein translocase SecG subunit
GPELGMEL_00805 9.6e-149 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPELGMEL_00806 1.9e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
GPELGMEL_00807 1.3e-171 whiA K May be required for sporulation
GPELGMEL_00808 1.1e-170 rapZ S Displays ATPase and GTPase activities
GPELGMEL_00809 7.1e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
GPELGMEL_00810 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GPELGMEL_00811 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GPELGMEL_00812 4.6e-127 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00813 4.1e-56 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00814 0.0 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00815 6.2e-140 S Domain of unknown function (DUF4194)
GPELGMEL_00816 6.9e-274 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00817 2e-13
GPELGMEL_00819 2.8e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPELGMEL_00820 4.7e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
GPELGMEL_00821 1.9e-300 ybiT S ABC transporter
GPELGMEL_00822 2.3e-173 S IMP dehydrogenase activity
GPELGMEL_00823 3.1e-275 pepC 3.4.22.40 E Peptidase C1-like family
GPELGMEL_00824 3.4e-146 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00825 2.8e-144
GPELGMEL_00826 9e-98
GPELGMEL_00829 1.5e-181 cat P Cation efflux family
GPELGMEL_00830 3.1e-75 S Psort location CytoplasmicMembrane, score
GPELGMEL_00831 6e-221 yxjG_1 E Psort location Cytoplasmic, score 8.87
GPELGMEL_00832 2e-143 4.1.1.44 S Carboxymuconolactone decarboxylase family
GPELGMEL_00833 4.6e-199 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
GPELGMEL_00834 6.7e-72 K MerR family regulatory protein
GPELGMEL_00835 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
GPELGMEL_00836 1.3e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GPELGMEL_00837 2.6e-119 yoaP E YoaP-like
GPELGMEL_00838 7.8e-174 xerH L Phage integrase family
GPELGMEL_00840 2.8e-134 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
GPELGMEL_00841 6e-87 K Psort location Cytoplasmic, score
GPELGMEL_00842 2.7e-102 S Fic/DOC family
GPELGMEL_00845 5.3e-57 ard S Antirestriction protein (ArdA)
GPELGMEL_00846 2.3e-08
GPELGMEL_00847 1.1e-83 M G5 domain protein
GPELGMEL_00848 1.2e-68
GPELGMEL_00851 3.7e-243 topB 5.99.1.2 L DNA topoisomerase
GPELGMEL_00854 2.8e-16 K Bacterial mobilisation protein (MobC)
GPELGMEL_00855 2.2e-36 S Pfam:CtkA_N
GPELGMEL_00857 2.9e-70 ecoRIIR 3.1.21.4 L EcoRII C terminal
GPELGMEL_00858 2.3e-112 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
GPELGMEL_00859 7e-144 S Fic/DOC family
GPELGMEL_00860 1.6e-137 L PFAM Relaxase mobilization nuclease family protein
GPELGMEL_00861 2.2e-86 2.7.11.1 S HipA-like C-terminal domain
GPELGMEL_00863 2.8e-40
GPELGMEL_00864 8e-49 S Domain of unknown function (DUF4913)
GPELGMEL_00865 6.7e-230 U TraM recognition site of TraD and TraG
GPELGMEL_00866 1.5e-22
GPELGMEL_00870 2e-201 traD S COG0433 Predicted ATPase
GPELGMEL_00871 3.4e-187
GPELGMEL_00872 4.8e-144
GPELGMEL_00873 1.3e-29
GPELGMEL_00874 4.1e-33
GPELGMEL_00875 3.3e-10
GPELGMEL_00876 1.8e-20
GPELGMEL_00877 1.1e-54 M Spy0128-like isopeptide containing domain
GPELGMEL_00878 7.6e-09 U Spy0128-like isopeptide containing domain
GPELGMEL_00879 0.0 XK27_00515 D Cell surface antigen C-terminus
GPELGMEL_00880 2.1e-39
GPELGMEL_00881 4.6e-51
GPELGMEL_00882 4.5e-22
GPELGMEL_00884 4.7e-31 parA D VirC1 protein
GPELGMEL_00885 5.8e-16 S Transcription factor WhiB
GPELGMEL_00886 2.9e-15 S Helix-turn-helix domain
GPELGMEL_00892 2.7e-17
GPELGMEL_00894 2.6e-194 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPELGMEL_00895 5.8e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
GPELGMEL_00896 6.4e-148 yeaZ 2.3.1.234 O Glycoprotease family
GPELGMEL_00897 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
GPELGMEL_00898 9.3e-178 holA 2.7.7.7 L DNA polymerase III delta subunit
GPELGMEL_00899 0.0 comE S Competence protein
GPELGMEL_00900 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
GPELGMEL_00901 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPELGMEL_00902 2.8e-141 ET Bacterial periplasmic substrate-binding proteins
GPELGMEL_00903 5.7e-172 corA P CorA-like Mg2+ transporter protein
GPELGMEL_00904 1.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
GPELGMEL_00905 5.2e-65 3.4.22.70 M Sortase family
GPELGMEL_00906 5.6e-83 3.4.22.70 M Sortase family
GPELGMEL_00907 3e-301 M domain protein
GPELGMEL_00908 2.7e-70 pdxH S Pfam:Pyridox_oxidase
GPELGMEL_00909 4.5e-233 XK27_00240 K Fic/DOC family
GPELGMEL_00911 3.3e-118
GPELGMEL_00912 2.5e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
GPELGMEL_00913 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GPELGMEL_00914 2.6e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPELGMEL_00915 7.6e-71 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPELGMEL_00916 6.1e-108 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
GPELGMEL_00917 1.1e-209 guaB 1.1.1.205 F IMP dehydrogenase family protein
GPELGMEL_00918 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
GPELGMEL_00919 1.1e-268 G ABC transporter substrate-binding protein
GPELGMEL_00920 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
GPELGMEL_00921 3.3e-96 M Peptidase family M23
GPELGMEL_00922 1.6e-61
GPELGMEL_00925 5e-125 XK27_06785 V ABC transporter
GPELGMEL_00926 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPELGMEL_00927 2.1e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GPELGMEL_00928 1.4e-139 S SdpI/YhfL protein family
GPELGMEL_00929 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
GPELGMEL_00930 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
GPELGMEL_00931 2.6e-216 yxjG_1 E Psort location Cytoplasmic, score 8.87
GPELGMEL_00932 6.1e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPELGMEL_00933 1.1e-108 J Acetyltransferase (GNAT) domain
GPELGMEL_00934 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPELGMEL_00936 2.9e-162 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
GPELGMEL_00937 5.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPELGMEL_00938 6.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GPELGMEL_00939 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
GPELGMEL_00940 7e-178 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
GPELGMEL_00941 5.2e-278 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GPELGMEL_00942 4.2e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
GPELGMEL_00943 3e-187 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GPELGMEL_00944 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
GPELGMEL_00945 4.6e-157 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
GPELGMEL_00946 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPELGMEL_00947 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
GPELGMEL_00948 3.9e-198 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GPELGMEL_00949 1.2e-157 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
GPELGMEL_00950 2.2e-248 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
GPELGMEL_00951 2e-74
GPELGMEL_00952 2.6e-307 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
GPELGMEL_00953 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
GPELGMEL_00954 1.9e-234 F Psort location CytoplasmicMembrane, score 10.00
GPELGMEL_00955 1.8e-217 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
GPELGMEL_00956 2.2e-287 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
GPELGMEL_00957 5e-145 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
GPELGMEL_00958 7.3e-233 hemN H Involved in the biosynthesis of porphyrin-containing compound
GPELGMEL_00959 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GPELGMEL_00960 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
GPELGMEL_00961 1.1e-133 S UPF0126 domain
GPELGMEL_00962 2.5e-227 ilvE 2.6.1.42 E Amino-transferase class IV
GPELGMEL_00964 2.6e-73 K Acetyltransferase (GNAT) domain
GPELGMEL_00965 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPELGMEL_00966 4.8e-93 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPELGMEL_00967 1e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPELGMEL_00968 8.5e-195 S alpha beta
GPELGMEL_00969 6.5e-25 yhjX EGP Major facilitator Superfamily
GPELGMEL_00970 2.6e-30 EGP Major facilitator Superfamily
GPELGMEL_00971 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPELGMEL_00972 3.1e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPELGMEL_00974 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPELGMEL_00975 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
GPELGMEL_00976 1.1e-39 nrdH O Glutaredoxin
GPELGMEL_00977 7e-121 K Bacterial regulatory proteins, tetR family
GPELGMEL_00978 5.1e-224 G Transmembrane secretion effector
GPELGMEL_00980 4.2e-269 S Psort location Cytoplasmic, score 8.87
GPELGMEL_00981 3.5e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GPELGMEL_00982 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
GPELGMEL_00983 1.7e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
GPELGMEL_00984 0.0 fadD 6.2.1.3 I AMP-binding enzyme
GPELGMEL_00985 2e-180 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPELGMEL_00986 1.2e-250 corC S CBS domain
GPELGMEL_00987 9.4e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPELGMEL_00988 5.9e-208 phoH T PhoH-like protein
GPELGMEL_00989 1.8e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
GPELGMEL_00990 2e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GPELGMEL_00992 3.5e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
GPELGMEL_00993 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPELGMEL_00994 2.7e-108 yitW S Iron-sulfur cluster assembly protein
GPELGMEL_00995 3.4e-100 iscU C SUF system FeS assembly protein, NifU family
GPELGMEL_00996 5e-240 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPELGMEL_00997 1e-142 sufC O FeS assembly ATPase SufC
GPELGMEL_00998 6.1e-235 sufD O FeS assembly protein SufD
GPELGMEL_00999 1.6e-290 sufB O FeS assembly protein SufB
GPELGMEL_01000 0.0 S L,D-transpeptidase catalytic domain
GPELGMEL_01001 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GPELGMEL_01002 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
GPELGMEL_01003 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
GPELGMEL_01004 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPELGMEL_01005 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPELGMEL_01006 9.3e-57 3.4.23.43 S Type IV leader peptidase family
GPELGMEL_01007 8.9e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPELGMEL_01008 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPELGMEL_01009 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPELGMEL_01010 2.5e-36
GPELGMEL_01011 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
GPELGMEL_01012 5.6e-129 pgm3 G Phosphoglycerate mutase family
GPELGMEL_01013 3.4e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
GPELGMEL_01014 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPELGMEL_01015 7.1e-142 lolD V ABC transporter
GPELGMEL_01016 5.3e-215 V FtsX-like permease family
GPELGMEL_01017 1.7e-61 S Domain of unknown function (DUF4418)
GPELGMEL_01018 0.0 pcrA 3.6.4.12 L DNA helicase
GPELGMEL_01019 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GPELGMEL_01020 2.8e-244 pbuX F Permease family
GPELGMEL_01021 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
GPELGMEL_01022 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPELGMEL_01023 3.5e-302 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GPELGMEL_01024 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
GPELGMEL_01025 5.1e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GPELGMEL_01026 9.3e-253 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GPELGMEL_01028 4.1e-212 ykiI
GPELGMEL_01029 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
GPELGMEL_01030 1.5e-123 3.6.1.13 L NUDIX domain
GPELGMEL_01031 9.9e-174 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
GPELGMEL_01032 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPELGMEL_01033 9.4e-101 pdtaR T Response regulator receiver domain protein
GPELGMEL_01034 1e-164 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
GPELGMEL_01035 1.4e-30 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
GPELGMEL_01036 1.7e-107 L Belongs to the 'phage' integrase family
GPELGMEL_01037 6.8e-52 3.1.21.3 V type I restriction modification DNA specificity domain
GPELGMEL_01038 1.6e-57 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
GPELGMEL_01039 1e-244 hsdM 2.1.1.72 V HsdM N-terminal domain
GPELGMEL_01040 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
GPELGMEL_01041 3.3e-36 pcrA1 3.6.4.12 F DNA helicase
GPELGMEL_01042 1.6e-101 E Binding-protein-dependent transport system inner membrane component
GPELGMEL_01043 1.4e-121 tcyA ET Bacterial periplasmic substrate-binding proteins
GPELGMEL_01044 3.2e-115 3.6.3.21 E ATPases associated with a variety of cellular activities
GPELGMEL_01045 7.2e-196 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
GPELGMEL_01047 2.2e-18 relB L RelB antitoxin
GPELGMEL_01049 2.5e-305 pyk 2.7.1.40 G Pyruvate kinase
GPELGMEL_01050 8.8e-176 terC P Integral membrane protein, TerC family
GPELGMEL_01051 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GPELGMEL_01052 9.1e-116 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPELGMEL_01053 8.3e-255 rpsA J Ribosomal protein S1
GPELGMEL_01054 1.9e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPELGMEL_01055 4.4e-176 P Zinc-uptake complex component A periplasmic
GPELGMEL_01056 2e-160 znuC P ATPases associated with a variety of cellular activities
GPELGMEL_01057 3.9e-140 znuB U ABC 3 transport family
GPELGMEL_01058 7.8e-88 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
GPELGMEL_01059 3e-102 carD K CarD-like/TRCF domain
GPELGMEL_01060 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPELGMEL_01061 2e-129 T Response regulator receiver domain protein
GPELGMEL_01062 6.8e-188 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
GPELGMEL_01063 8.5e-139 ctsW S Phosphoribosyl transferase domain
GPELGMEL_01064 1.1e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
GPELGMEL_01065 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
GPELGMEL_01066 3.3e-222
GPELGMEL_01067 0.0 S Glycosyl transferase, family 2
GPELGMEL_01068 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
GPELGMEL_01069 5.7e-208 K Cell envelope-related transcriptional attenuator domain
GPELGMEL_01071 6.9e-170 K Cell envelope-related transcriptional attenuator domain
GPELGMEL_01072 0.0 D FtsK/SpoIIIE family
GPELGMEL_01073 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
GPELGMEL_01074 6e-277 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
GPELGMEL_01075 3.6e-144 yplQ S Haemolysin-III related
GPELGMEL_01076 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPELGMEL_01077 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
GPELGMEL_01078 1.2e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
GPELGMEL_01079 1.8e-91
GPELGMEL_01081 3.7e-182 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
GPELGMEL_01082 7.6e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
GPELGMEL_01083 2e-71 divIC D Septum formation initiator
GPELGMEL_01084 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GPELGMEL_01085 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPELGMEL_01086 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GPELGMEL_01087 5.2e-98 2.3.1.183 M Acetyltransferase (GNAT) domain
GPELGMEL_01088 0.0 S Uncharacterised protein family (UPF0182)
GPELGMEL_01089 7.3e-181 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
GPELGMEL_01090 6.2e-40 ybdD S Selenoprotein, putative
GPELGMEL_01091 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
GPELGMEL_01092 1e-51 azlD E Branched-chain amino acid transport protein (AzlD)
GPELGMEL_01093 1.4e-142 azlC E AzlC protein
GPELGMEL_01094 3e-87 M Protein of unknown function (DUF3737)
GPELGMEL_01095 1.1e-80 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GPELGMEL_01096 7.1e-144 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
GPELGMEL_01097 2.6e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
GPELGMEL_01098 3.6e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPELGMEL_01099 3.6e-218 patB 4.4.1.8 E Aminotransferase, class I II
GPELGMEL_01100 5.3e-147 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GPELGMEL_01101 1.2e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPELGMEL_01102 0.0 lysX S Uncharacterised conserved protein (DUF2156)
GPELGMEL_01103 6.5e-241 S Putative esterase
GPELGMEL_01104 4.6e-141 ybbL V ATPases associated with a variety of cellular activities
GPELGMEL_01105 5.1e-134 ybbM V Uncharacterised protein family (UPF0014)
GPELGMEL_01106 4.4e-278 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
GPELGMEL_01107 2.1e-126 S Enoyl-(Acyl carrier protein) reductase
GPELGMEL_01108 1.1e-226 rutG F Permease family
GPELGMEL_01109 5.8e-157 3.1.3.73 G Phosphoglycerate mutase family
GPELGMEL_01110 8.5e-139 K helix_turn_helix, arabinose operon control protein
GPELGMEL_01111 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
GPELGMEL_01112 4.2e-45 3.1.21.3 V type I restriction modification DNA specificity domain
GPELGMEL_01113 1.8e-84 O peptidyl-tyrosine sulfation
GPELGMEL_01114 7e-74 S Psort location Cytoplasmic, score 8.87
GPELGMEL_01115 1e-119 S Psort location Cytoplasmic, score 8.87
GPELGMEL_01116 4.8e-91 3.1.21.3 V Type I restriction modification DNA specificity domain
GPELGMEL_01117 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
GPELGMEL_01118 1.1e-172 L Phage integrase family
GPELGMEL_01119 3.4e-136 S Sulfite exporter TauE/SafE
GPELGMEL_01120 6.1e-68 S ECF transporter, substrate-specific component
GPELGMEL_01121 4.9e-79 2.7.1.48 F uridine kinase
GPELGMEL_01122 1.2e-158 korD 1.2.7.3 C Domain of unknown function (DUF362)
GPELGMEL_01123 1.6e-185 C Na H antiporter family protein
GPELGMEL_01124 5.5e-165 MA20_14895 S Conserved hypothetical protein 698
GPELGMEL_01125 1e-94
GPELGMEL_01126 3.7e-16 feoB P transporter of a GTP-driven Fe(2 ) uptake system
GPELGMEL_01127 8.6e-56 KLT Protein tyrosine kinase
GPELGMEL_01128 7.4e-259 EGP Transmembrane secretion effector
GPELGMEL_01129 1.3e-25 cysB 4.2.1.22 EGP Major facilitator Superfamily
GPELGMEL_01130 1e-42 cysB 4.2.1.22 EGP Major facilitator Superfamily
GPELGMEL_01131 5.9e-12
GPELGMEL_01132 2e-17 yccF S Inner membrane component domain
GPELGMEL_01133 1.1e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GPELGMEL_01134 1.4e-142 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPELGMEL_01135 2.4e-264 pip 3.4.11.5 S alpha/beta hydrolase fold
GPELGMEL_01136 0.0 tcsS2 T Histidine kinase
GPELGMEL_01137 7.2e-130 K helix_turn_helix, Lux Regulon
GPELGMEL_01138 0.0 MV MacB-like periplasmic core domain
GPELGMEL_01139 5.1e-142 V ABC transporter, ATP-binding protein
GPELGMEL_01140 8.2e-193 K helix_turn_helix ASNC type
GPELGMEL_01141 6.9e-150 P Cobalt transport protein
GPELGMEL_01142 5.1e-306 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
GPELGMEL_01143 2.8e-94 XK27_01265 S ECF-type riboflavin transporter, S component
GPELGMEL_01144 5.9e-252 metY 2.5.1.49 E Aminotransferase class-V
GPELGMEL_01145 5.6e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
GPELGMEL_01146 4e-83 yraN L Belongs to the UPF0102 family
GPELGMEL_01147 2.3e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
GPELGMEL_01148 3.8e-254 dprA 5.99.1.2 LU DNA recombination-mediator protein A
GPELGMEL_01149 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
GPELGMEL_01150 2e-177 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
GPELGMEL_01151 4.8e-117 safC S O-methyltransferase
GPELGMEL_01152 8.6e-246 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GPELGMEL_01155 1.4e-240 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPELGMEL_01156 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GPELGMEL_01157 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GPELGMEL_01158 9.2e-311 E ABC transporter, substrate-binding protein, family 5
GPELGMEL_01159 3.4e-251 EGP Major facilitator Superfamily
GPELGMEL_01160 1.2e-172 yjfF U Branched-chain amino acid transport system / permease component
GPELGMEL_01161 1.5e-181 ytfT U Branched-chain amino acid transport system / permease component
GPELGMEL_01162 6e-288 ytfR 3.6.3.17 G ATPases associated with a variety of cellular activities
GPELGMEL_01163 2.4e-165 G Periplasmic binding protein domain
GPELGMEL_01164 0.0 lpqB S Lipoprotein LpqB beta-propeller domain
GPELGMEL_01165 1.7e-285 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
GPELGMEL_01166 1.5e-132 KT Transcriptional regulatory protein, C terminal
GPELGMEL_01167 3.1e-251 rarA L Recombination factor protein RarA
GPELGMEL_01168 0.0 L DEAD DEAH box helicase
GPELGMEL_01169 4.3e-191 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
GPELGMEL_01170 1e-199 gluD E Binding-protein-dependent transport system inner membrane component
GPELGMEL_01171 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
GPELGMEL_01172 6.8e-153 gluB ET Belongs to the bacterial solute-binding protein 3 family
GPELGMEL_01173 4.4e-144 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
GPELGMEL_01174 6.7e-139 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
GPELGMEL_01175 2.7e-280 glnP E Binding-protein-dependent transport system inner membrane component
GPELGMEL_01176 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GPELGMEL_01177 5.3e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
GPELGMEL_01178 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
GPELGMEL_01179 1.6e-140 3.5.2.10 S Creatinine amidohydrolase
GPELGMEL_01180 9.4e-245 proP EGP Sugar (and other) transporter
GPELGMEL_01181 4.7e-285 purR QT Purine catabolism regulatory protein-like family
GPELGMEL_01182 1.5e-255 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
GPELGMEL_01183 0.0 clpC O ATPase family associated with various cellular activities (AAA)
GPELGMEL_01184 4.6e-188 uspA T Belongs to the universal stress protein A family
GPELGMEL_01185 1.4e-180 S Protein of unknown function (DUF3027)
GPELGMEL_01186 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
GPELGMEL_01187 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
GPELGMEL_01188 2.6e-132 KT Response regulator receiver domain protein
GPELGMEL_01189 1.3e-124
GPELGMEL_01191 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GPELGMEL_01192 8.5e-77 S LytR cell envelope-related transcriptional attenuator
GPELGMEL_01193 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPELGMEL_01194 4e-182 moxR S ATPase family associated with various cellular activities (AAA)
GPELGMEL_01195 1e-173 S Protein of unknown function DUF58
GPELGMEL_01196 3.6e-91
GPELGMEL_01197 2.3e-190 S von Willebrand factor (vWF) type A domain
GPELGMEL_01198 5e-182 S von Willebrand factor (vWF) type A domain
GPELGMEL_01199 1.3e-62
GPELGMEL_01200 1.6e-277 S PGAP1-like protein
GPELGMEL_01201 1.6e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
GPELGMEL_01202 0.0 S Lysylphosphatidylglycerol synthase TM region
GPELGMEL_01203 1.4e-41 hup L Belongs to the bacterial histone-like protein family
GPELGMEL_01204 1.8e-57
GPELGMEL_01205 9.7e-141 C FMN binding
GPELGMEL_01206 3.7e-279 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GPELGMEL_01207 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
GPELGMEL_01208 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
GPELGMEL_01209 5.1e-301 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
GPELGMEL_01210 4.4e-283 arc O AAA ATPase forming ring-shaped complexes
GPELGMEL_01211 1.6e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
GPELGMEL_01212 1.1e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPELGMEL_01213 2.7e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GPELGMEL_01214 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPELGMEL_01215 4.2e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPELGMEL_01216 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GPELGMEL_01217 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
GPELGMEL_01219 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
GPELGMEL_01220 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
GPELGMEL_01221 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
GPELGMEL_01222 1.1e-239 carA 6.3.5.5 F Belongs to the CarA family
GPELGMEL_01223 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPELGMEL_01224 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPELGMEL_01225 9.5e-233 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPELGMEL_01226 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPELGMEL_01227 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GPELGMEL_01228 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPELGMEL_01229 8.1e-188 yocS S SBF-like CPA transporter family (DUF4137)
GPELGMEL_01231 2.9e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
GPELGMEL_01232 6.5e-226 M Glycosyl transferase 4-like domain
GPELGMEL_01233 1.1e-228 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPELGMEL_01234 4.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GPELGMEL_01235 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
GPELGMEL_01236 1.9e-36
GPELGMEL_01237 4e-306 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
GPELGMEL_01238 1e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPELGMEL_01239 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GPELGMEL_01240 2.8e-235 purD 6.3.4.13 F Belongs to the GARS family
GPELGMEL_01241 1.6e-247 EGP Major facilitator Superfamily
GPELGMEL_01242 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
GPELGMEL_01243 2.1e-213 1.1.1.1 C Iron-containing alcohol dehydrogenase
GPELGMEL_01244 1.3e-128 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
GPELGMEL_01245 9.1e-189 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
GPELGMEL_01246 9.4e-203 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
GPELGMEL_01247 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
GPELGMEL_01248 2.3e-89 zur P Belongs to the Fur family
GPELGMEL_01249 1.3e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPELGMEL_01250 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPELGMEL_01251 1.2e-183 adh3 C Zinc-binding dehydrogenase
GPELGMEL_01252 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPELGMEL_01253 6.8e-257 macB_8 V MacB-like periplasmic core domain
GPELGMEL_01254 1.7e-146 M Conserved repeat domain
GPELGMEL_01255 3.4e-129 V ATPases associated with a variety of cellular activities
GPELGMEL_01256 7.4e-75
GPELGMEL_01257 6.9e-15 S Domain of unknown function (DUF4143)
GPELGMEL_01258 3.1e-127 XK27_08050 O prohibitin homologues
GPELGMEL_01259 1.4e-43 XAC3035 O Glutaredoxin
GPELGMEL_01260 2.8e-15 P Belongs to the ABC transporter superfamily
GPELGMEL_01261 3.2e-75 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
GPELGMEL_01262 3.1e-220 mtnE 2.6.1.83 E Aminotransferase class I and II
GPELGMEL_01263 4.9e-98 metI P Psort location CytoplasmicMembrane, score 9.99
GPELGMEL_01264 1.9e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPELGMEL_01265 3.4e-155 metQ M NLPA lipoprotein
GPELGMEL_01266 3.4e-199 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPELGMEL_01267 6.9e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
GPELGMEL_01268 1.1e-150 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
GPELGMEL_01269 3.6e-120 E Binding-protein-dependent transport system inner membrane component
GPELGMEL_01270 1.1e-108 papP E Binding-protein-dependent transport system inner membrane component
GPELGMEL_01271 2.7e-114 K acetyltransferase
GPELGMEL_01275 0.0 tetP J Elongation factor G, domain IV
GPELGMEL_01277 2.3e-176 ydcZ S Putative inner membrane exporter, YdcZ
GPELGMEL_01279 8.1e-216 ybiR P Citrate transporter
GPELGMEL_01280 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GPELGMEL_01281 5.9e-307 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPELGMEL_01282 3.1e-270 yhdG E aromatic amino acid transport protein AroP K03293
GPELGMEL_01283 1e-101 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPELGMEL_01284 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GPELGMEL_01285 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
GPELGMEL_01286 0.0 macB_2 V ATPases associated with a variety of cellular activities
GPELGMEL_01287 1e-218 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
GPELGMEL_01288 2e-191 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
GPELGMEL_01289 4e-139 sapF E ATPases associated with a variety of cellular activities
GPELGMEL_01290 7.1e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
GPELGMEL_01291 3.6e-139 EP Binding-protein-dependent transport system inner membrane component
GPELGMEL_01292 2.2e-166 P Binding-protein-dependent transport system inner membrane component
GPELGMEL_01293 3.5e-294 E ABC transporter, substrate-binding protein, family 5
GPELGMEL_01294 6e-241 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPELGMEL_01295 5e-142 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GPELGMEL_01296 1.1e-275 G Bacterial extracellular solute-binding protein
GPELGMEL_01297 2.2e-246 G Bacterial extracellular solute-binding protein
GPELGMEL_01298 0.0 abfA1 3.2.1.55 GH51 G arabinose metabolic process
GPELGMEL_01299 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
GPELGMEL_01300 3.5e-51 S Patatin-like phospholipase
GPELGMEL_01301 3.8e-176 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
GPELGMEL_01302 2.3e-301 E ABC transporter, substrate-binding protein, family 5
GPELGMEL_01303 1.2e-21 S Patatin-like phospholipase
GPELGMEL_01304 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GPELGMEL_01305 7.8e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
GPELGMEL_01306 4.8e-117 S Vitamin K epoxide reductase
GPELGMEL_01307 5e-173 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
GPELGMEL_01308 3.6e-32 S Protein of unknown function (DUF3107)
GPELGMEL_01309 1.8e-268 mphA S Aminoglycoside phosphotransferase
GPELGMEL_01310 1.6e-282 uvrD2 3.6.4.12 L DNA helicase
GPELGMEL_01311 3.3e-294 S Zincin-like metallopeptidase
GPELGMEL_01312 2.2e-154 lon T Belongs to the peptidase S16 family
GPELGMEL_01313 6.5e-75 S Protein of unknown function (DUF3052)
GPELGMEL_01315 6.8e-239 2.7.11.1 NU Tfp pilus assembly protein FimV
GPELGMEL_01316 8.5e-218 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
GPELGMEL_01317 5.6e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPELGMEL_01318 0.0 I acetylesterase activity
GPELGMEL_01319 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
GPELGMEL_01320 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPELGMEL_01321 1.3e-216 iunH1 3.2.2.1 F nucleoside hydrolase
GPELGMEL_01322 2.6e-205 P NMT1/THI5 like
GPELGMEL_01323 1.9e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
GPELGMEL_01324 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
GPELGMEL_01325 2.8e-241 lacY P LacY proton/sugar symporter
GPELGMEL_01326 1.2e-191 K helix_turn _helix lactose operon repressor
GPELGMEL_01327 3e-60 S Thiamine-binding protein
GPELGMEL_01328 1.2e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPELGMEL_01329 3.2e-133 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GPELGMEL_01330 9.9e-155 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPELGMEL_01331 0.0
GPELGMEL_01332 0.0 pilT NU Type II/IV secretion system protein
GPELGMEL_01333 0.0 pulE NU Type II/IV secretion system protein
GPELGMEL_01334 4.9e-137 ppdC NU Prokaryotic N-terminal methylation motif
GPELGMEL_01335 2.1e-104 S Prokaryotic N-terminal methylation motif
GPELGMEL_01336 2.4e-46 pilA NU Prokaryotic N-terminal methylation motif
GPELGMEL_01337 4.7e-230 pilC U Type II secretion system (T2SS), protein F
GPELGMEL_01338 0.0
GPELGMEL_01339 2.4e-150 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
GPELGMEL_01340 8.7e-190 pilM NU Type IV pilus assembly protein PilM;
GPELGMEL_01341 8.1e-166 pilN NU PFAM Fimbrial assembly family protein
GPELGMEL_01342 1e-105 S Pilus assembly protein, PilO
GPELGMEL_01343 1.3e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
GPELGMEL_01344 1.1e-244 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPELGMEL_01345 5.6e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPELGMEL_01346 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GPELGMEL_01347 6.9e-41 yggT S YGGT family
GPELGMEL_01348 4.5e-31 3.1.21.3 V DivIVA protein
GPELGMEL_01349 4.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPELGMEL_01350 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GPELGMEL_01351 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
GPELGMEL_01352 2.4e-259 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPELGMEL_01353 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPELGMEL_01354 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
GPELGMEL_01355 1.5e-122
GPELGMEL_01356 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPELGMEL_01357 3.1e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
GPELGMEL_01358 3.1e-264 glnA2 6.3.1.2 E glutamine synthetase
GPELGMEL_01359 7.9e-32 S Domain of unknown function (DUF5067)
GPELGMEL_01360 1.6e-166 S Domain of unknown function (DUF5067)
GPELGMEL_01361 3.6e-139 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GPELGMEL_01362 9.5e-220 EGP Major facilitator Superfamily
GPELGMEL_01363 3.2e-118 ytrE V ATPases associated with a variety of cellular activities
GPELGMEL_01364 8.7e-29 2.7.13.3 T Histidine kinase
GPELGMEL_01365 5.4e-57 T helix_turn_helix, Lux Regulon
GPELGMEL_01366 3.4e-83
GPELGMEL_01367 4.9e-188 V N-Acetylmuramoyl-L-alanine amidase
GPELGMEL_01368 8.6e-193
GPELGMEL_01369 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
GPELGMEL_01370 5.9e-114 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
GPELGMEL_01371 4.9e-271 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPELGMEL_01372 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
GPELGMEL_01373 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPELGMEL_01374 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPELGMEL_01375 1e-53 M Lysin motif
GPELGMEL_01376 2.9e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPELGMEL_01377 8.7e-218 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
GPELGMEL_01378 0.0 L DNA helicase
GPELGMEL_01379 7e-92 mraZ K Belongs to the MraZ family
GPELGMEL_01380 1.3e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GPELGMEL_01381 6.7e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GPELGMEL_01382 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
GPELGMEL_01383 1.1e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPELGMEL_01384 8.4e-263 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GPELGMEL_01385 1.2e-192 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPELGMEL_01386 2.1e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPELGMEL_01387 2.4e-202 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
GPELGMEL_01388 6.4e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPELGMEL_01389 2.3e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
GPELGMEL_01390 5e-140 ftsQ 6.3.2.4 D Cell division protein FtsQ
GPELGMEL_01391 8.4e-248 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
GPELGMEL_01392 1.6e-27
GPELGMEL_01393 3.5e-220 S Metal-independent alpha-mannosidase (GH125)
GPELGMEL_01394 1.1e-164 2.7.1.4 G pfkB family carbohydrate kinase
GPELGMEL_01395 1.7e-218 GK ROK family
GPELGMEL_01396 6.1e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
GPELGMEL_01397 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
GPELGMEL_01398 4.7e-192 dppC EP Binding-protein-dependent transport system inner membrane component
GPELGMEL_01399 0.0 P Belongs to the ABC transporter superfamily
GPELGMEL_01400 9.9e-94 3.6.1.55 F NUDIX domain
GPELGMEL_01401 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
GPELGMEL_01402 4.6e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
GPELGMEL_01403 1.9e-186 V Acetyltransferase (GNAT) domain
GPELGMEL_01404 7.1e-281 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPELGMEL_01405 1.1e-98 sigH K Belongs to the sigma-70 factor family. ECF subfamily
GPELGMEL_01406 4.1e-37
GPELGMEL_01407 2.4e-186 galM 5.1.3.3 G Aldose 1-epimerase
GPELGMEL_01408 7.9e-172 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPELGMEL_01409 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPELGMEL_01410 1.8e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPELGMEL_01411 3.4e-111 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
GPELGMEL_01412 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPELGMEL_01413 2.1e-25 rpmI J Ribosomal protein L35
GPELGMEL_01414 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPELGMEL_01415 2e-177 xerD D recombinase XerD
GPELGMEL_01416 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
GPELGMEL_01417 2.1e-151 nrtR 3.6.1.55 F NUDIX hydrolase
GPELGMEL_01418 1.3e-249 naiP U Sugar (and other) transporter
GPELGMEL_01419 0.0 typA T Elongation factor G C-terminus
GPELGMEL_01420 4e-104
GPELGMEL_01421 3.7e-190 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
GPELGMEL_01422 8.9e-195 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
GPELGMEL_01423 2.8e-34
GPELGMEL_01424 5.2e-08
GPELGMEL_01425 1.6e-171 xerC D Belongs to the 'phage' integrase family. XerC subfamily
GPELGMEL_01426 9.1e-240 G Bacterial extracellular solute-binding protein
GPELGMEL_01427 2.1e-129 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GPELGMEL_01428 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GPELGMEL_01429 0.0 cydD V ABC transporter transmembrane region
GPELGMEL_01430 0.0 fadD 6.2.1.3 I AMP-binding enzyme
GPELGMEL_01431 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
GPELGMEL_01432 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
GPELGMEL_01433 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
GPELGMEL_01434 2.1e-210 K helix_turn _helix lactose operon repressor
GPELGMEL_01435 2.4e-286 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
GPELGMEL_01436 1.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GPELGMEL_01437 1.6e-241 hom 1.1.1.3 E Homoserine dehydrogenase
GPELGMEL_01438 2.7e-299 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GPELGMEL_01439 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GPELGMEL_01440 5.7e-272 mmuP E amino acid
GPELGMEL_01441 2.7e-59 psp1 3.5.99.10 J Endoribonuclease L-PSP
GPELGMEL_01443 1.8e-121 cyaA 4.6.1.1 S CYTH
GPELGMEL_01444 8.4e-171 trxA2 O Tetratricopeptide repeat
GPELGMEL_01445 2.7e-180
GPELGMEL_01446 2e-193
GPELGMEL_01447 6.8e-149 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
GPELGMEL_01448 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GPELGMEL_01449 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GPELGMEL_01450 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPELGMEL_01451 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPELGMEL_01452 3.8e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPELGMEL_01453 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPELGMEL_01454 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPELGMEL_01455 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPELGMEL_01456 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
GPELGMEL_01457 4.5e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GPELGMEL_01459 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GPELGMEL_01460 3.9e-193 yfdV S Membrane transport protein
GPELGMEL_01461 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
GPELGMEL_01462 7.1e-175 M LPXTG-motif cell wall anchor domain protein
GPELGMEL_01463 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
GPELGMEL_01464 3.4e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GPELGMEL_01465 9.4e-98 mntP P Probably functions as a manganese efflux pump
GPELGMEL_01466 4.9e-134
GPELGMEL_01467 4.9e-134 KT Transcriptional regulatory protein, C terminal
GPELGMEL_01468 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPELGMEL_01469 1.9e-289 E Bacterial extracellular solute-binding proteins, family 5 Middle
GPELGMEL_01470 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GPELGMEL_01471 0.0 S domain protein
GPELGMEL_01472 1e-69 tyrA 5.4.99.5 E Chorismate mutase type II
GPELGMEL_01473 1.3e-79 K helix_turn_helix ASNC type
GPELGMEL_01474 1.9e-247 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPELGMEL_01475 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
GPELGMEL_01476 2.1e-51 S Protein of unknown function (DUF2469)
GPELGMEL_01477 2e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
GPELGMEL_01478 6.6e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPELGMEL_01479 8.6e-287 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GPELGMEL_01480 1.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPELGMEL_01481 6.2e-134 K Psort location Cytoplasmic, score
GPELGMEL_01482 3.8e-144 spoU 2.1.1.185 J RNA methyltransferase TrmH family
GPELGMEL_01483 8.4e-114 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPELGMEL_01484 0.0 scrB 3.2.1.26, 3.2.1.97 GH101,GH32 N Glycosyl hydrolases family 43
GPELGMEL_01485 0.0 N Bacterial Ig-like domain 2
GPELGMEL_01486 1.6e-172 rmuC S RmuC family
GPELGMEL_01487 1.2e-134 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
GPELGMEL_01488 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GPELGMEL_01489 5.7e-163 fahA Q Fumarylacetoacetate (FAA) hydrolase family
GPELGMEL_01490 1.1e-147 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPELGMEL_01491 2.5e-80
GPELGMEL_01492 3.1e-209 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPELGMEL_01493 8.1e-22 M Protein of unknown function (DUF3152)
GPELGMEL_01494 1.4e-125 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
GPELGMEL_01496 1.7e-70 rplI J Binds to the 23S rRNA
GPELGMEL_01497 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPELGMEL_01498 3.8e-66 ssb1 L Single-stranded DNA-binding protein
GPELGMEL_01499 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
GPELGMEL_01500 3.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPELGMEL_01501 1.6e-174 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPELGMEL_01502 1.1e-259 EGP Major Facilitator Superfamily
GPELGMEL_01503 3.3e-167 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
GPELGMEL_01504 3.3e-197 K helix_turn _helix lactose operon repressor
GPELGMEL_01505 1e-60
GPELGMEL_01506 8.2e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPELGMEL_01507 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
GPELGMEL_01508 5.7e-194 M Glycosyltransferase like family 2
GPELGMEL_01509 1.3e-148 rgpC U Transport permease protein
GPELGMEL_01510 2.2e-243 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
GPELGMEL_01511 0.0 rgpF M Rhamnan synthesis protein F
GPELGMEL_01512 3.5e-165 I Acyltransferase family
GPELGMEL_01513 2.9e-152 yfdH 2.4.2.53 GT2 M Glycosyltransferase like family 2
GPELGMEL_01514 8.7e-191 S Glucosyl transferase GtrII
GPELGMEL_01515 9.5e-147 1.1.1.339 GM NAD dependent epimerase/dehydratase family
GPELGMEL_01516 2.6e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPELGMEL_01517 1e-281 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GPELGMEL_01518 2e-174 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPELGMEL_01519 0.0 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
GPELGMEL_01520 6.4e-257 S AAA domain
GPELGMEL_01521 6.7e-70
GPELGMEL_01522 7.1e-10
GPELGMEL_01523 4.3e-26 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
GPELGMEL_01524 4.2e-225 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
GPELGMEL_01525 5.6e-59
GPELGMEL_01527 3.9e-154 EGP Major facilitator Superfamily
GPELGMEL_01528 1.8e-203 E ABC transporter, substrate-binding protein, family 5
GPELGMEL_01529 0.0 E ABC transporter, substrate-binding protein, family 5
GPELGMEL_01530 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
GPELGMEL_01531 4.1e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
GPELGMEL_01532 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
GPELGMEL_01533 1.4e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
GPELGMEL_01534 1.7e-151 S Protein of unknown function (DUF3710)
GPELGMEL_01535 2.4e-133 S Protein of unknown function (DUF3159)
GPELGMEL_01536 4.8e-243 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPELGMEL_01537 2e-74
GPELGMEL_01538 0.0 ctpE P E1-E2 ATPase
GPELGMEL_01539 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GPELGMEL_01540 1.4e-248 VP1224 V Psort location CytoplasmicMembrane, score 9.99
GPELGMEL_01541 4.7e-109 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
GPELGMEL_01542 9.8e-213 rhaR1 K helix_turn_helix, arabinose operon control protein
GPELGMEL_01543 8.9e-229 V ABC-2 family transporter protein
GPELGMEL_01544 3.8e-224 V ABC-2 family transporter protein
GPELGMEL_01545 4.4e-191 V ATPases associated with a variety of cellular activities
GPELGMEL_01546 1.1e-245 T Histidine kinase
GPELGMEL_01547 9e-116 K helix_turn_helix, Lux Regulon
GPELGMEL_01548 0.0 S Protein of unknown function DUF262
GPELGMEL_01549 1.8e-127 K helix_turn_helix, Lux Regulon
GPELGMEL_01550 5.1e-243 T Histidine kinase
GPELGMEL_01551 1.4e-57 S Domain of unknown function (DUF5067)
GPELGMEL_01552 1.7e-127 ybhL S Belongs to the BI1 family
GPELGMEL_01553 8e-177 ydeD EG EamA-like transporter family
GPELGMEL_01554 1.1e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
GPELGMEL_01555 1e-281 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPELGMEL_01556 5.4e-192 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPELGMEL_01557 7.2e-11 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPELGMEL_01558 0.0 ftsK D FtsK SpoIIIE family protein
GPELGMEL_01559 4.1e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPELGMEL_01560 5.5e-98 cinA 3.5.1.42 S Belongs to the CinA family
GPELGMEL_01561 1.6e-80 K Helix-turn-helix XRE-family like proteins
GPELGMEL_01562 4.3e-46 S Protein of unknown function (DUF3046)
GPELGMEL_01563 5.4e-212 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPELGMEL_01564 1.9e-121 recX S Modulates RecA activity
GPELGMEL_01565 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPELGMEL_01566 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GPELGMEL_01567 3.4e-194 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPELGMEL_01568 2.9e-97
GPELGMEL_01569 1.9e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
GPELGMEL_01570 0.0 pknL 2.7.11.1 KLT PASTA
GPELGMEL_01571 2.2e-196 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
GPELGMEL_01572 1.1e-118
GPELGMEL_01573 9.7e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GPELGMEL_01574 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
GPELGMEL_01575 1.5e-222 G Major Facilitator Superfamily
GPELGMEL_01576 2.5e-242 T PhoQ Sensor
GPELGMEL_01577 2.4e-79 S Protein of unknown function (DUF2975)
GPELGMEL_01578 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
GPELGMEL_01579 0.0 lhr L DEAD DEAH box helicase
GPELGMEL_01580 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
GPELGMEL_01581 3e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
GPELGMEL_01582 6.8e-150 S Protein of unknown function (DUF3071)
GPELGMEL_01583 1e-47 S Domain of unknown function (DUF4193)
GPELGMEL_01584 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
GPELGMEL_01585 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPELGMEL_01586 1.2e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPELGMEL_01587 4.6e-234 dinF V MatE
GPELGMEL_01588 0.0 S LPXTG-motif cell wall anchor domain protein
GPELGMEL_01590 3.2e-59 L Helix-turn-helix domain
GPELGMEL_01591 1.4e-101 V Abi-like protein
GPELGMEL_01592 1.1e-74
GPELGMEL_01593 5.4e-108 metI P Binding-protein-dependent transport system inner membrane component
GPELGMEL_01594 5.5e-147 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPELGMEL_01595 4.8e-146 metQ P NLPA lipoprotein
GPELGMEL_01596 1.7e-156 S Sucrose-6F-phosphate phosphohydrolase
GPELGMEL_01597 1.8e-225 S Peptidase dimerisation domain
GPELGMEL_01598 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GPELGMEL_01599 4.5e-31
GPELGMEL_01600 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
GPELGMEL_01601 7.4e-166 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPELGMEL_01602 2.9e-79 S Protein of unknown function (DUF3000)
GPELGMEL_01603 2e-236 rnd 3.1.13.5 J 3'-5' exonuclease
GPELGMEL_01604 1.2e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GPELGMEL_01605 2.7e-132 yebE S DUF218 domain
GPELGMEL_01606 7.6e-129 E Psort location Cytoplasmic, score 8.87
GPELGMEL_01607 1.2e-158 msbA2 3.6.3.44 V ABC transporter transmembrane region
GPELGMEL_01608 4.4e-135 3.6.3.44 V ABC transporter
GPELGMEL_01609 2.7e-126 KLT serine threonine protein kinase
GPELGMEL_01610 2e-227 L DNA binding domain of tn916 integrase
GPELGMEL_01611 3.6e-31 L Excisionase from transposon Tn916
GPELGMEL_01612 6.9e-200 L Replication initiation factor
GPELGMEL_01613 2.6e-94 K Cro/C1-type HTH DNA-binding domain
GPELGMEL_01614 1.2e-35 vanZ V VanZ-like protein
GPELGMEL_01615 1.4e-13
GPELGMEL_01616 5.6e-79 S SnoaL-like domain
GPELGMEL_01617 0.0 KLT Lanthionine synthetase C-like protein
GPELGMEL_01618 6.5e-122 K helix_turn_helix, Lux Regulon
GPELGMEL_01619 6.9e-159 2.7.13.3 T Histidine kinase
GPELGMEL_01620 1.7e-40 K helix_turn_helix, mercury resistance
GPELGMEL_01621 1.4e-49 C Flavodoxin
GPELGMEL_01622 1.3e-166 C Aldo/keto reductase family
GPELGMEL_01623 3.6e-81 4.1.1.44 S Cupin domain
GPELGMEL_01624 2.8e-42 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
GPELGMEL_01625 6.6e-147 S phosphoesterase or phosphohydrolase
GPELGMEL_01626 2.7e-213
GPELGMEL_01627 5.6e-69
GPELGMEL_01628 6.3e-290 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
GPELGMEL_01629 1.5e-115 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPELGMEL_01630 1.7e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPELGMEL_01631 0.0 eccCa D FtsK/SpoIIIE family
GPELGMEL_01632 9.6e-157 T Forkhead associated domain
GPELGMEL_01633 1e-191
GPELGMEL_01634 4.4e-55
GPELGMEL_01635 3.7e-188
GPELGMEL_01636 9.8e-142
GPELGMEL_01637 1.3e-175
GPELGMEL_01638 3.7e-257 O Subtilase family
GPELGMEL_01640 1.5e-43 S Proteins of 100 residues with WXG
GPELGMEL_01641 1.1e-47 esxU S Proteins of 100 residues with WXG
GPELGMEL_01642 5.9e-226 snm S WXG100 protein secretion system (Wss), protein YukD
GPELGMEL_01643 0.0 O Type VII secretion system ESX-1, transport TM domain B
GPELGMEL_01644 1e-169
GPELGMEL_01645 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
GPELGMEL_01646 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPELGMEL_01647 9.5e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPELGMEL_01648 0.0 pacS 3.6.3.54 P E1-E2 ATPase
GPELGMEL_01649 1.1e-38 csoR S Metal-sensitive transcriptional repressor
GPELGMEL_01650 2.4e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GPELGMEL_01651 1.5e-245 G Major Facilitator Superfamily
GPELGMEL_01652 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
GPELGMEL_01653 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
GPELGMEL_01654 1.8e-262 KLT Protein tyrosine kinase
GPELGMEL_01655 0.0 S Fibronectin type 3 domain
GPELGMEL_01656 3.1e-227 S ATPase family associated with various cellular activities (AAA)
GPELGMEL_01657 5.4e-220 S Protein of unknown function DUF58
GPELGMEL_01658 0.0 E Transglutaminase-like superfamily
GPELGMEL_01659 5.8e-163 3.1.3.16 T Sigma factor PP2C-like phosphatases
GPELGMEL_01660 1.3e-104 B Belongs to the OprB family
GPELGMEL_01661 1.2e-97 T Forkhead associated domain
GPELGMEL_01662 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPELGMEL_01663 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPELGMEL_01664 5.7e-99
GPELGMEL_01665 3.5e-182 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
GPELGMEL_01666 3.3e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GPELGMEL_01667 7.2e-253 S UPF0210 protein
GPELGMEL_01668 7.1e-43 gcvR T Belongs to the UPF0237 family
GPELGMEL_01669 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
GPELGMEL_01670 6.1e-178 K helix_turn _helix lactose operon repressor
GPELGMEL_01671 3.5e-115 S Protein of unknown function, DUF624
GPELGMEL_01672 3.4e-169 G Binding-protein-dependent transport system inner membrane component
GPELGMEL_01673 1.6e-177 G Binding-protein-dependent transport system inner membrane component
GPELGMEL_01674 6.4e-309 G Bacterial extracellular solute-binding protein
GPELGMEL_01676 9e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
GPELGMEL_01677 1.1e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
GPELGMEL_01678 3.4e-141 glpR K DeoR C terminal sensor domain
GPELGMEL_01679 8.8e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
GPELGMEL_01680 2e-219 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
GPELGMEL_01681 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
GPELGMEL_01682 2.3e-133 glxR K helix_turn_helix, cAMP Regulatory protein
GPELGMEL_01683 4.1e-217 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
GPELGMEL_01684 1.9e-85 J TM2 domain
GPELGMEL_01685 8.4e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GPELGMEL_01686 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
GPELGMEL_01687 1.5e-236 S Uncharacterized conserved protein (DUF2183)
GPELGMEL_01688 2.7e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
GPELGMEL_01689 9.6e-208 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
GPELGMEL_01690 3.4e-160 mhpC I Alpha/beta hydrolase family
GPELGMEL_01691 1.7e-113 F Domain of unknown function (DUF4916)
GPELGMEL_01692 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
GPELGMEL_01693 5.6e-170 S G5
GPELGMEL_01694 2.1e-88
GPELGMEL_01695 2e-103 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
GPELGMEL_01696 5.3e-118 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
GPELGMEL_01697 2.5e-20 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
GPELGMEL_01698 3.3e-80 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
GPELGMEL_01699 1.6e-44
GPELGMEL_01700 1e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
GPELGMEL_01701 1.9e-62 S Protein of unknown function (DUF4235)
GPELGMEL_01702 2.4e-135 G Phosphoglycerate mutase family
GPELGMEL_01703 1.4e-256 amyE G Bacterial extracellular solute-binding protein
GPELGMEL_01704 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
GPELGMEL_01705 5.2e-182 K Periplasmic binding protein-like domain
GPELGMEL_01706 9.3e-181 K Psort location Cytoplasmic, score
GPELGMEL_01707 3.7e-154 msmF G Binding-protein-dependent transport system inner membrane component
GPELGMEL_01708 4e-153 rafG G ABC transporter permease
GPELGMEL_01709 4.9e-105 S Protein of unknown function, DUF624
GPELGMEL_01710 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
GPELGMEL_01711 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
GPELGMEL_01712 3.5e-143 S HAD-hyrolase-like
GPELGMEL_01713 6e-129 traX S TraX protein
GPELGMEL_01714 8.3e-193 K Psort location Cytoplasmic, score
GPELGMEL_01715 4.5e-121 S membrane transporter protein
GPELGMEL_01716 2.4e-59 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
GPELGMEL_01717 2.2e-145 S Mitochondrial biogenesis AIM24
GPELGMEL_01718 0.0 dnaK O Heat shock 70 kDa protein
GPELGMEL_01719 5.9e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPELGMEL_01720 3.9e-158 dnaJ1 O DnaJ molecular chaperone homology domain
GPELGMEL_01721 4.5e-115 hspR K transcriptional regulator, MerR family
GPELGMEL_01722 1.9e-46
GPELGMEL_01723 2.5e-129 S HAD hydrolase, family IA, variant 3
GPELGMEL_01725 5.8e-126 dedA S SNARE associated Golgi protein
GPELGMEL_01726 1.6e-17 3.2.1.78 GH26 G Glycosyl hydrolase family 26
GPELGMEL_01727 2.6e-189 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPELGMEL_01728 6.6e-107
GPELGMEL_01729 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPELGMEL_01730 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
GPELGMEL_01731 6.6e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
GPELGMEL_01732 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
GPELGMEL_01733 2.1e-264 lacS G Psort location CytoplasmicMembrane, score 10.00
GPELGMEL_01734 5.6e-211 GK ROK family
GPELGMEL_01735 4.2e-242 G Bacterial extracellular solute-binding protein
GPELGMEL_01736 7.5e-147 G Binding-protein-dependent transport system inner membrane component
GPELGMEL_01737 1.1e-162 G ABC transporter permease
GPELGMEL_01738 3e-173 2.7.1.2 GK ROK family
GPELGMEL_01739 0.0 G Glycosyl hydrolase family 20, domain 2
GPELGMEL_01740 7.6e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GPELGMEL_01741 6.3e-230 nagA 3.5.1.25 G Amidohydrolase family
GPELGMEL_01742 2.3e-187 lacR K Transcriptional regulator, LacI family
GPELGMEL_01743 0.0 T Diguanylate cyclase, GGDEF domain
GPELGMEL_01744 1.2e-120 3.2.1.14 GH18 S Carbohydrate binding domain
GPELGMEL_01745 4.2e-104 3.2.1.14 GH18 S Carbohydrate binding domain
GPELGMEL_01746 0.0 M probably involved in cell wall
GPELGMEL_01747 1.1e-230 M Protein of unknown function (DUF2961)
GPELGMEL_01748 3.8e-156 I alpha/beta hydrolase fold
GPELGMEL_01749 5e-27 S Psort location Cytoplasmic, score 8.87
GPELGMEL_01750 9.7e-216 lipA I Hydrolase, alpha beta domain protein
GPELGMEL_01751 0.0 mdlA2 V ABC transporter
GPELGMEL_01752 0.0 yknV V ABC transporter
GPELGMEL_01753 4e-125
GPELGMEL_01754 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
GPELGMEL_01755 9.2e-223 K helix_turn _helix lactose operon repressor
GPELGMEL_01756 8.1e-22 rafA 3.2.1.22 G alpha-galactosidase
GPELGMEL_01757 0.0 G Alpha-L-arabinofuranosidase C-terminus
GPELGMEL_01758 2.2e-179 tatD L TatD related DNase
GPELGMEL_01759 0.0 kup P Transport of potassium into the cell
GPELGMEL_01760 1e-167 S Glutamine amidotransferase domain
GPELGMEL_01761 5.1e-150 T HD domain
GPELGMEL_01762 2.9e-157 V ABC transporter
GPELGMEL_01763 2.1e-241 V ABC transporter permease
GPELGMEL_01764 0.0 S Psort location CytoplasmicMembrane, score 9.99
GPELGMEL_01766 2.4e-245 S zinc finger
GPELGMEL_01767 2e-71 S Bacterial PH domain
GPELGMEL_01768 1.5e-76
GPELGMEL_01769 4.1e-147 V Domain of unknown function (DUF3427)
GPELGMEL_01770 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
GPELGMEL_01771 8.1e-185 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
GPELGMEL_01772 8.6e-74 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
GPELGMEL_01773 5.6e-233 aspB E Aminotransferase class-V
GPELGMEL_01774 3e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
GPELGMEL_01775 1.3e-99 tmp1 S Domain of unknown function (DUF4391)
GPELGMEL_01776 1.9e-22
GPELGMEL_01777 7.9e-43 V ATPases associated with a variety of cellular activities
GPELGMEL_01779 6.5e-196 S Endonuclease/Exonuclease/phosphatase family
GPELGMEL_01781 7e-41 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPELGMEL_01782 8.9e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPELGMEL_01783 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
GPELGMEL_01784 1.6e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GPELGMEL_01785 3.9e-156 hgdC I BadF/BadG/BcrA/BcrD ATPase family
GPELGMEL_01786 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
GPELGMEL_01787 1e-253 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
GPELGMEL_01788 4.2e-115 K Bacterial regulatory proteins, tetR family
GPELGMEL_01789 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
GPELGMEL_01790 2.5e-107 K Bacterial regulatory proteins, tetR family
GPELGMEL_01791 7.5e-239 G Transporter major facilitator family protein
GPELGMEL_01792 1e-234 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
GPELGMEL_01793 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
GPELGMEL_01794 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
GPELGMEL_01795 2.3e-108 K Bacterial regulatory proteins, tetR family
GPELGMEL_01796 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
GPELGMEL_01797 8e-221 lmrB U Major Facilitator Superfamily
GPELGMEL_01798 2.6e-15 K helix_turn_helix, mercury resistance
GPELGMEL_01799 6.8e-118 K Periplasmic binding protein domain
GPELGMEL_01800 4.4e-215 EGP Major facilitator Superfamily
GPELGMEL_01801 0.0 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
GPELGMEL_01802 1.9e-181 G Transporter major facilitator family protein
GPELGMEL_01803 3.7e-197 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GPELGMEL_01804 5.1e-107 K Bacterial regulatory proteins, tetR family
GPELGMEL_01805 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
GPELGMEL_01806 1.3e-96 K MarR family
GPELGMEL_01807 0.0 V ABC transporter, ATP-binding protein
GPELGMEL_01808 0.0 V ABC transporter transmembrane region
GPELGMEL_01809 9e-184 lacR K Transcriptional regulator, LacI family
GPELGMEL_01810 1.1e-254 lacS G Psort location CytoplasmicMembrane, score 10.00
GPELGMEL_01811 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPELGMEL_01812 0.0 cas3 L DEAD-like helicases superfamily
GPELGMEL_01813 1.9e-303 casA L CRISPR system CASCADE complex protein CasA
GPELGMEL_01814 4.2e-110 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
GPELGMEL_01815 2.6e-192 casC L CT1975-like protein
GPELGMEL_01816 1.2e-113 casD S CRISPR-associated protein (Cas_Cas5)
GPELGMEL_01817 9.7e-121 casE S CRISPR_assoc
GPELGMEL_01818 2e-186 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GPELGMEL_01819 7.4e-126 S Phospholipase/Carboxylesterase
GPELGMEL_01820 5.6e-241 patB 4.4.1.8 E Aminotransferase, class I II
GPELGMEL_01821 1.2e-183 K LysR substrate binding domain protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)