ORF_ID e_value Gene_name EC_number CAZy COGs Description
LPKPLPPA_00001 1.4e-158 lysR5 K LysR substrate binding domain
LPKPLPPA_00002 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
LPKPLPPA_00003 3e-251 G Major Facilitator
LPKPLPPA_00004 1.6e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LPKPLPPA_00005 9.4e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LPKPLPPA_00006 9.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LPKPLPPA_00007 1.1e-278 yjeM E Amino Acid
LPKPLPPA_00008 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LPKPLPPA_00009 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LPKPLPPA_00010 9.3e-124 srtA 3.4.22.70 M sortase family
LPKPLPPA_00011 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LPKPLPPA_00012 4.5e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LPKPLPPA_00013 0.0 dnaK O Heat shock 70 kDa protein
LPKPLPPA_00014 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LPKPLPPA_00015 2.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LPKPLPPA_00016 6.7e-121 S GyrI-like small molecule binding domain
LPKPLPPA_00017 1.6e-282 lsa S ABC transporter
LPKPLPPA_00018 7.6e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LPKPLPPA_00019 1.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LPKPLPPA_00020 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LPKPLPPA_00021 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LPKPLPPA_00022 6e-46 rplGA J ribosomal protein
LPKPLPPA_00023 2e-46 ylxR K Protein of unknown function (DUF448)
LPKPLPPA_00024 3.3e-217 nusA K Participates in both transcription termination and antitermination
LPKPLPPA_00025 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
LPKPLPPA_00026 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPKPLPPA_00027 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LPKPLPPA_00028 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LPKPLPPA_00029 1.1e-136 cdsA 2.7.7.41 S Belongs to the CDS family
LPKPLPPA_00030 5.5e-135 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LPKPLPPA_00031 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LPKPLPPA_00032 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LPKPLPPA_00033 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LPKPLPPA_00034 2.8e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
LPKPLPPA_00035 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
LPKPLPPA_00036 9.8e-117 plsC 2.3.1.51 I Acyltransferase
LPKPLPPA_00037 8.6e-201 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LPKPLPPA_00038 6.1e-300 mdlB V ABC transporter
LPKPLPPA_00039 0.0 mdlA V ABC transporter
LPKPLPPA_00040 1.5e-30 yneF S Uncharacterised protein family (UPF0154)
LPKPLPPA_00041 1.5e-34 ynzC S UPF0291 protein
LPKPLPPA_00042 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LPKPLPPA_00043 1.1e-115 ung2 3.2.2.27 L Uracil-DNA glycosylase
LPKPLPPA_00044 6.5e-75 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
LPKPLPPA_00045 2.7e-117 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LPKPLPPA_00046 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LPKPLPPA_00047 2.2e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LPKPLPPA_00048 7.4e-97 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LPKPLPPA_00049 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LPKPLPPA_00050 3.2e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LPKPLPPA_00051 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LPKPLPPA_00052 1.6e-287 pipD E Dipeptidase
LPKPLPPA_00053 7.8e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LPKPLPPA_00054 0.0 smc D Required for chromosome condensation and partitioning
LPKPLPPA_00055 1.6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LPKPLPPA_00056 0.0 oppA E ABC transporter substrate-binding protein
LPKPLPPA_00057 2.8e-298 oppA E ABC transporter substrate-binding protein
LPKPLPPA_00058 3.2e-30 oppA E ABC transporter substrate-binding protein
LPKPLPPA_00059 2.1e-163 oppC P Binding-protein-dependent transport system inner membrane component
LPKPLPPA_00060 7.5e-180 oppB P ABC transporter permease
LPKPLPPA_00061 4.4e-180 oppF P Belongs to the ABC transporter superfamily
LPKPLPPA_00062 1.1e-192 oppD P Belongs to the ABC transporter superfamily
LPKPLPPA_00063 2.6e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LPKPLPPA_00064 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LPKPLPPA_00065 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LPKPLPPA_00066 9.6e-308 yloV S DAK2 domain fusion protein YloV
LPKPLPPA_00067 1.4e-57 asp S Asp23 family, cell envelope-related function
LPKPLPPA_00068 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LPKPLPPA_00069 1e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
LPKPLPPA_00070 3.1e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LPKPLPPA_00071 1.4e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LPKPLPPA_00072 0.0 KLT serine threonine protein kinase
LPKPLPPA_00073 4.5e-140 stp 3.1.3.16 T phosphatase
LPKPLPPA_00074 1.2e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LPKPLPPA_00075 7.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LPKPLPPA_00076 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LPKPLPPA_00077 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LPKPLPPA_00078 4.7e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
LPKPLPPA_00079 4.6e-48
LPKPLPPA_00080 1.7e-264 recN L May be involved in recombinational repair of damaged DNA
LPKPLPPA_00081 3.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LPKPLPPA_00082 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LPKPLPPA_00083 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LPKPLPPA_00084 3.6e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LPKPLPPA_00085 8.1e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LPKPLPPA_00086 8e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LPKPLPPA_00087 2.2e-73 yqhY S Asp23 family, cell envelope-related function
LPKPLPPA_00088 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LPKPLPPA_00089 2.8e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LPKPLPPA_00090 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LPKPLPPA_00091 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LPKPLPPA_00092 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
LPKPLPPA_00093 1.2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPKPLPPA_00094 6.3e-246 S Uncharacterized protein conserved in bacteria (DUF2325)
LPKPLPPA_00095 1.2e-12
LPKPLPPA_00096 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LPKPLPPA_00097 1.2e-92 S ECF-type riboflavin transporter, S component
LPKPLPPA_00098 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
LPKPLPPA_00099 1.4e-59
LPKPLPPA_00100 5.2e-56 K Acetyltransferase (GNAT) domain
LPKPLPPA_00101 4.7e-305 S Predicted membrane protein (DUF2207)
LPKPLPPA_00102 1.2e-187 yhjX P Major Facilitator Superfamily
LPKPLPPA_00103 6.9e-83 I Carboxylesterase family
LPKPLPPA_00104 2.7e-63 I Carboxylesterase family
LPKPLPPA_00105 7e-161 rhaS6 K helix_turn_helix, arabinose operon control protein
LPKPLPPA_00106 2.1e-168 2.7.1.2 GK ROK family
LPKPLPPA_00107 4.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
LPKPLPPA_00108 8.6e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
LPKPLPPA_00109 0.0 oppA E ABC transporter substrate-binding protein
LPKPLPPA_00110 1.2e-76 K MerR HTH family regulatory protein
LPKPLPPA_00111 1.8e-265 lmrB EGP Major facilitator Superfamily
LPKPLPPA_00112 7.1e-98 S Domain of unknown function (DUF4811)
LPKPLPPA_00113 3.5e-128 pnb C nitroreductase
LPKPLPPA_00114 2.6e-224 I transferase activity, transferring acyl groups other than amino-acyl groups
LPKPLPPA_00115 2.1e-108 fic D Fic/DOC family
LPKPLPPA_00116 6.6e-72
LPKPLPPA_00117 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LPKPLPPA_00119 5.2e-122 S CAAX protease self-immunity
LPKPLPPA_00120 2.5e-141 S haloacid dehalogenase-like hydrolase
LPKPLPPA_00121 0.0 pepN 3.4.11.2 E aminopeptidase
LPKPLPPA_00122 4.2e-50
LPKPLPPA_00123 1e-19
LPKPLPPA_00124 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LPKPLPPA_00125 1.6e-233 sptS 2.7.13.3 T Histidine kinase
LPKPLPPA_00126 5.3e-116 K response regulator
LPKPLPPA_00127 1.9e-112 2.7.6.5 T Region found in RelA / SpoT proteins
LPKPLPPA_00128 8.3e-21 ltrA S Bacterial low temperature requirement A protein (LtrA)
LPKPLPPA_00129 6.9e-66 O OsmC-like protein
LPKPLPPA_00130 1.6e-288 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LPKPLPPA_00131 4.4e-180 E ABC transporter, ATP-binding protein
LPKPLPPA_00132 0.0 infB UW LPXTG-motif cell wall anchor domain protein
LPKPLPPA_00133 0.0 3.1.31.1 M domain protein
LPKPLPPA_00134 1.6e-266 E amino acid
LPKPLPPA_00135 1.6e-171 K LysR substrate binding domain
LPKPLPPA_00136 0.0 1.3.5.4 C FAD binding domain
LPKPLPPA_00137 4.4e-242 brnQ U Component of the transport system for branched-chain amino acids
LPKPLPPA_00138 2.5e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LPKPLPPA_00139 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
LPKPLPPA_00140 3.2e-88 S Peptidase propeptide and YPEB domain
LPKPLPPA_00141 2.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LPKPLPPA_00142 1.7e-249 yhjX_2 P Major Facilitator Superfamily
LPKPLPPA_00143 4.6e-236 yhjX_2 P Major Facilitator Superfamily
LPKPLPPA_00144 3.3e-163 arbZ I Phosphate acyltransferases
LPKPLPPA_00145 2.5e-183 arbY M Glycosyl transferase family 8
LPKPLPPA_00146 9.4e-183 arbY M Glycosyl transferase family 8
LPKPLPPA_00147 3.2e-155 arbx M Glycosyl transferase family 8
LPKPLPPA_00148 3.6e-148 arbV 2.3.1.51 I Acyl-transferase
LPKPLPPA_00151 1.2e-129 K response regulator
LPKPLPPA_00152 0.0 vicK 2.7.13.3 T Histidine kinase
LPKPLPPA_00153 3.5e-252 yycH S YycH protein
LPKPLPPA_00154 1.4e-142 yycI S YycH protein
LPKPLPPA_00155 3.3e-149 vicX 3.1.26.11 S domain protein
LPKPLPPA_00156 3.5e-182 htrA 3.4.21.107 O serine protease
LPKPLPPA_00157 9.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LPKPLPPA_00158 2.1e-109 P Cobalt transport protein
LPKPLPPA_00159 4.3e-250 cbiO1 S ABC transporter, ATP-binding protein
LPKPLPPA_00160 4.8e-94 S ABC-type cobalt transport system, permease component
LPKPLPPA_00161 2.3e-170 K helix_turn_helix, arabinose operon control protein
LPKPLPPA_00162 2e-147 htpX O Belongs to the peptidase M48B family
LPKPLPPA_00163 9.9e-92 lemA S LemA family
LPKPLPPA_00164 8.3e-183 ybiR P Citrate transporter
LPKPLPPA_00165 1.3e-69 S Iron-sulphur cluster biosynthesis
LPKPLPPA_00166 1.7e-16
LPKPLPPA_00167 1.7e-154
LPKPLPPA_00169 4.3e-247 ydaM M Glycosyl transferase
LPKPLPPA_00170 7.1e-214 G Glycosyl hydrolases family 8
LPKPLPPA_00171 4.5e-120 yfbR S HD containing hydrolase-like enzyme
LPKPLPPA_00172 3.7e-162 L HNH nucleases
LPKPLPPA_00173 9.6e-138 glnQ E ABC transporter, ATP-binding protein
LPKPLPPA_00174 8.2e-280 glnP P ABC transporter permease
LPKPLPPA_00175 1.2e-106 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LPKPLPPA_00176 1.5e-64 yeaO S Protein of unknown function, DUF488
LPKPLPPA_00177 1.6e-127 terC P Integral membrane protein TerC family
LPKPLPPA_00178 2.3e-93 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
LPKPLPPA_00179 1.4e-98 rimL J Acetyltransferase (GNAT) domain
LPKPLPPA_00180 1.5e-88 2.3.1.57 K Acetyltransferase (GNAT) family
LPKPLPPA_00181 3.7e-137 2.4.2.3 F Phosphorylase superfamily
LPKPLPPA_00182 3.1e-83 6.3.3.2 S ASCH
LPKPLPPA_00183 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LPKPLPPA_00184 6.1e-160 rbsU U ribose uptake protein RbsU
LPKPLPPA_00185 1.6e-159 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
LPKPLPPA_00186 1.1e-289 V ABC-type multidrug transport system, ATPase and permease components
LPKPLPPA_00187 1.6e-272 V ABC-type multidrug transport system, ATPase and permease components
LPKPLPPA_00188 5.2e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LPKPLPPA_00189 4.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
LPKPLPPA_00190 4.3e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LPKPLPPA_00191 4.4e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
LPKPLPPA_00192 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LPKPLPPA_00193 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LPKPLPPA_00194 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LPKPLPPA_00195 4.8e-90 ypmB S Protein conserved in bacteria
LPKPLPPA_00196 2.9e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
LPKPLPPA_00197 6.7e-116 dnaD L DnaD domain protein
LPKPLPPA_00198 1.2e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LPKPLPPA_00199 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
LPKPLPPA_00200 1.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LPKPLPPA_00201 4.2e-106 ypsA S Belongs to the UPF0398 family
LPKPLPPA_00202 2e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LPKPLPPA_00203 2.4e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LPKPLPPA_00204 6.3e-240 cpdA S Calcineurin-like phosphoesterase
LPKPLPPA_00205 1.2e-88 degV S DegV family
LPKPLPPA_00206 1e-47 degV S DegV family
LPKPLPPA_00207 9.9e-58
LPKPLPPA_00208 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LPKPLPPA_00209 2.3e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LPKPLPPA_00210 1.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LPKPLPPA_00211 2.8e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LPKPLPPA_00212 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
LPKPLPPA_00213 0.0 FbpA K Fibronectin-binding protein
LPKPLPPA_00214 3.8e-64
LPKPLPPA_00215 3.8e-162 degV S EDD domain protein, DegV family
LPKPLPPA_00216 3.7e-151
LPKPLPPA_00217 6.7e-167 K Transcriptional regulator
LPKPLPPA_00218 1.8e-203 xerS L Belongs to the 'phage' integrase family
LPKPLPPA_00219 7.2e-124 yoaK S Protein of unknown function (DUF1275)
LPKPLPPA_00220 7.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LPKPLPPA_00221 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
LPKPLPPA_00222 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
LPKPLPPA_00223 2.2e-179 K Transcriptional regulator
LPKPLPPA_00224 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LPKPLPPA_00225 0.0 typA T GTP-binding protein TypA
LPKPLPPA_00226 5.6e-209 ftsW D Belongs to the SEDS family
LPKPLPPA_00227 6.1e-52 ylbG S UPF0298 protein
LPKPLPPA_00228 1.6e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
LPKPLPPA_00229 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LPKPLPPA_00230 2.5e-186 ylbL T Belongs to the peptidase S16 family
LPKPLPPA_00231 2.4e-79 comEA L Competence protein ComEA
LPKPLPPA_00232 0.0 comEC S Competence protein ComEC
LPKPLPPA_00233 1.2e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
LPKPLPPA_00234 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
LPKPLPPA_00235 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LPKPLPPA_00236 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LPKPLPPA_00237 7.7e-160
LPKPLPPA_00238 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LPKPLPPA_00239 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LPKPLPPA_00240 3.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LPKPLPPA_00241 2e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
LPKPLPPA_00242 6.7e-89 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LPKPLPPA_00243 1.5e-81
LPKPLPPA_00244 1.2e-70 S Domain of unknown function (DUF4767)
LPKPLPPA_00245 7.7e-225
LPKPLPPA_00246 3.7e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LPKPLPPA_00248 4.5e-76 S HIRAN
LPKPLPPA_00250 7.2e-164 htpX O Peptidase family M48
LPKPLPPA_00251 7e-32
LPKPLPPA_00252 4e-223 patA 2.6.1.1 E Aminotransferase
LPKPLPPA_00253 6.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LPKPLPPA_00254 4.8e-125 E GDSL-like Lipase/Acylhydrolase family
LPKPLPPA_00255 1.5e-08 E GDSL-like Lipase/Acylhydrolase family
LPKPLPPA_00256 1.4e-106 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LPKPLPPA_00257 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPKPLPPA_00258 1e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LPKPLPPA_00259 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LPKPLPPA_00260 2e-47 yqeY S YqeY-like protein
LPKPLPPA_00261 4.7e-174 phoH T phosphate starvation-inducible protein PhoH
LPKPLPPA_00262 1.2e-91 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LPKPLPPA_00263 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LPKPLPPA_00264 1.6e-137 recO L Involved in DNA repair and RecF pathway recombination
LPKPLPPA_00265 3.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LPKPLPPA_00266 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LPKPLPPA_00267 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LPKPLPPA_00268 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LPKPLPPA_00269 2.5e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
LPKPLPPA_00270 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LPKPLPPA_00271 1.2e-246 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LPKPLPPA_00272 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
LPKPLPPA_00273 3.3e-124 skfE V ATPases associated with a variety of cellular activities
LPKPLPPA_00274 2.1e-138
LPKPLPPA_00275 2.3e-108
LPKPLPPA_00276 8.1e-22
LPKPLPPA_00277 1e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LPKPLPPA_00278 4e-133
LPKPLPPA_00279 2.5e-167
LPKPLPPA_00280 2e-229 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
LPKPLPPA_00281 3.5e-52 ybjQ S Belongs to the UPF0145 family
LPKPLPPA_00282 8.3e-161 XK27_05540 S DUF218 domain
LPKPLPPA_00283 1.4e-87 yxeH S hydrolase
LPKPLPPA_00284 2.5e-52 yxeH S hydrolase
LPKPLPPA_00285 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LPKPLPPA_00286 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LPKPLPPA_00287 8.9e-116 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LPKPLPPA_00288 2.6e-109 lacA 2.3.1.79 S Transferase hexapeptide repeat
LPKPLPPA_00289 1.8e-124 magIII L Base excision DNA repair protein, HhH-GPD family
LPKPLPPA_00290 3.3e-166 akr5f 1.1.1.346 S reductase
LPKPLPPA_00291 1.9e-54 C Aldo/keto reductase family
LPKPLPPA_00292 2.9e-14 C Aldo/keto reductase family
LPKPLPPA_00293 9e-122 ybhL S Belongs to the BI1 family
LPKPLPPA_00294 2.3e-105 4.1.1.45 S Amidohydrolase
LPKPLPPA_00295 1.5e-33 4.1.1.45 S Amidohydrolase
LPKPLPPA_00296 5.7e-244 yrvN L AAA C-terminal domain
LPKPLPPA_00297 7.3e-58 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
LPKPLPPA_00298 1.3e-53 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
LPKPLPPA_00299 2.5e-86 XK27_09675 K Acetyltransferase (GNAT) domain
LPKPLPPA_00300 7.9e-69 ogt 2.1.1.63 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
LPKPLPPA_00301 6.2e-76 K Transcriptional regulator
LPKPLPPA_00302 5.2e-08 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
LPKPLPPA_00303 6.9e-80 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
LPKPLPPA_00304 4e-95 K Acetyltransferase (GNAT) family
LPKPLPPA_00305 1.5e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
LPKPLPPA_00306 3.1e-93 dps P Belongs to the Dps family
LPKPLPPA_00307 4.6e-35 copZ C Heavy-metal-associated domain
LPKPLPPA_00308 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
LPKPLPPA_00309 5.5e-50 K LytTr DNA-binding domain
LPKPLPPA_00310 1.3e-21 cylB V ABC-2 type transporter
LPKPLPPA_00311 2.4e-68 S pyridoxamine 5-phosphate
LPKPLPPA_00312 1.7e-50 yobV1 K WYL domain
LPKPLPPA_00313 1.3e-70 yobV1 K WYL domain
LPKPLPPA_00314 4.1e-30 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
LPKPLPPA_00315 2.3e-63 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LPKPLPPA_00316 4.1e-264 npr 1.11.1.1 C NADH oxidase
LPKPLPPA_00317 1.9e-32 G Major facilitator Superfamily
LPKPLPPA_00318 4.9e-61 S Sulfite exporter TauE/SafE
LPKPLPPA_00319 1.2e-89 mdt(A) EGP Major facilitator Superfamily
LPKPLPPA_00320 7.2e-88 mdt(A) EGP Major facilitator Superfamily
LPKPLPPA_00321 2.1e-117 GM NAD(P)H-binding
LPKPLPPA_00322 1.7e-231 E Alpha/beta hydrolase of unknown function (DUF1100)
LPKPLPPA_00323 9.2e-101 K Transcriptional regulator C-terminal region
LPKPLPPA_00325 4.9e-156 C Aldo keto reductase
LPKPLPPA_00326 3.9e-126 lmrA 3.6.3.44 V ABC transporter
LPKPLPPA_00327 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
LPKPLPPA_00328 1.7e-32 mta K helix_turn_helix, mercury resistance
LPKPLPPA_00329 4.4e-35 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
LPKPLPPA_00330 1.4e-189 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LPKPLPPA_00331 1.2e-41 yphH S Cupin domain
LPKPLPPA_00332 8.6e-290 V ABC-type multidrug transport system, ATPase and permease components
LPKPLPPA_00333 3.2e-292 P ABC transporter
LPKPLPPA_00334 1.9e-75 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
LPKPLPPA_00335 2.5e-11 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
LPKPLPPA_00336 5.1e-231 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
LPKPLPPA_00337 2.7e-48
LPKPLPPA_00338 5.2e-68 K HxlR family
LPKPLPPA_00339 4.5e-17 L Plasmid pRiA4b ORF-3-like protein
LPKPLPPA_00340 2.7e-32 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LPKPLPPA_00341 1.4e-11 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LPKPLPPA_00342 4.6e-247 brnQ U Component of the transport system for branched-chain amino acids
LPKPLPPA_00343 5.8e-63 S Putative adhesin
LPKPLPPA_00344 3.9e-113 3.6.1.55 F NUDIX domain
LPKPLPPA_00345 1.8e-110 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LPKPLPPA_00346 1.1e-36 comGC U Required for transformation and DNA binding
LPKPLPPA_00347 4.7e-177 comGB NU type II secretion system
LPKPLPPA_00348 5.8e-180 comGA NU Type II IV secretion system protein
LPKPLPPA_00349 1.5e-132 yebC K Transcriptional regulatory protein
LPKPLPPA_00350 7.3e-97 S VanZ like family
LPKPLPPA_00351 4.3e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LPKPLPPA_00352 4.5e-163 znuA P Belongs to the bacterial solute-binding protein 9 family
LPKPLPPA_00353 8.5e-150 yisY 1.11.1.10 S Alpha/beta hydrolase family
LPKPLPPA_00354 4.8e-115
LPKPLPPA_00355 8e-179 S Putative adhesin
LPKPLPPA_00356 5.3e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LPKPLPPA_00357 8.6e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LPKPLPPA_00358 4.4e-149 S Sucrose-6F-phosphate phosphohydrolase
LPKPLPPA_00359 2.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LPKPLPPA_00360 8.1e-174 ybbR S YbbR-like protein
LPKPLPPA_00361 3.4e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LPKPLPPA_00362 1.3e-209 potD P ABC transporter
LPKPLPPA_00363 8.5e-137 potC P ABC transporter permease
LPKPLPPA_00364 2.7e-130 potB P ABC transporter permease
LPKPLPPA_00365 5.9e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LPKPLPPA_00366 4.4e-166 murB 1.3.1.98 M Cell wall formation
LPKPLPPA_00367 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
LPKPLPPA_00368 1.3e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
LPKPLPPA_00369 2.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LPKPLPPA_00370 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LPKPLPPA_00371 8e-157 ycsE S Sucrose-6F-phosphate phosphohydrolase
LPKPLPPA_00372 2.9e-93
LPKPLPPA_00373 6.6e-91
LPKPLPPA_00375 1e-107 3.2.2.20 K acetyltransferase
LPKPLPPA_00376 2.3e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LPKPLPPA_00377 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LPKPLPPA_00378 2.5e-28 secG U Preprotein translocase
LPKPLPPA_00379 1.2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LPKPLPPA_00380 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LPKPLPPA_00381 1.3e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LPKPLPPA_00382 1.6e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LPKPLPPA_00383 2.3e-187 cggR K Putative sugar-binding domain
LPKPLPPA_00385 1.2e-277 ycaM E amino acid
LPKPLPPA_00386 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LPKPLPPA_00387 6.2e-171 whiA K May be required for sporulation
LPKPLPPA_00388 4.9e-193 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LPKPLPPA_00389 6e-160 rapZ S Displays ATPase and GTPase activities
LPKPLPPA_00390 1.1e-90 S Short repeat of unknown function (DUF308)
LPKPLPPA_00391 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LPKPLPPA_00392 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LPKPLPPA_00393 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LPKPLPPA_00394 1.6e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LPKPLPPA_00395 5.2e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LPKPLPPA_00396 1.4e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LPKPLPPA_00397 9.2e-181 lacR K Transcriptional regulator
LPKPLPPA_00398 5.4e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LPKPLPPA_00399 1.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LPKPLPPA_00400 6.8e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LPKPLPPA_00401 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LPKPLPPA_00402 4.1e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LPKPLPPA_00403 3.1e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LPKPLPPA_00404 1.2e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LPKPLPPA_00405 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LPKPLPPA_00406 1.9e-65 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LPKPLPPA_00407 3.6e-27 pncA Q Isochorismatase family
LPKPLPPA_00408 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LPKPLPPA_00409 5.7e-126 alkD L DNA alkylation repair enzyme
LPKPLPPA_00410 2.9e-128 XK27_06785 V ABC transporter, ATP-binding protein
LPKPLPPA_00411 0.0 XK27_06780 V ABC transporter permease
LPKPLPPA_00412 0.0 pepO 3.4.24.71 O Peptidase family M13
LPKPLPPA_00413 4.8e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
LPKPLPPA_00414 5.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LPKPLPPA_00415 3.3e-283 thrC 4.2.3.1 E Threonine synthase
LPKPLPPA_00416 5.3e-231 hom1 1.1.1.3 E homoserine dehydrogenase
LPKPLPPA_00417 3.3e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LPKPLPPA_00418 4.2e-161 lysR7 K LysR substrate binding domain
LPKPLPPA_00419 0.0 1.3.5.4 C FMN_bind
LPKPLPPA_00420 8.4e-119 drgA C nitroreductase
LPKPLPPA_00421 2.8e-28
LPKPLPPA_00422 8.4e-50
LPKPLPPA_00423 2e-42 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
LPKPLPPA_00424 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
LPKPLPPA_00425 2.2e-139
LPKPLPPA_00426 2e-105 speG J Acetyltransferase (GNAT) domain
LPKPLPPA_00427 1e-09 K sequence-specific DNA binding
LPKPLPPA_00428 1.3e-54 K sequence-specific DNA binding
LPKPLPPA_00429 1.2e-141 S Protein of unknown function (DUF975)
LPKPLPPA_00430 1e-127 qmcA O prohibitin homologues
LPKPLPPA_00431 2e-149 ropB K Helix-turn-helix domain
LPKPLPPA_00432 2e-294 V ABC-type multidrug transport system, ATPase and permease components
LPKPLPPA_00433 1.7e-84 C nitroreductase
LPKPLPPA_00434 5e-282 V ABC transporter transmembrane region
LPKPLPPA_00435 1.1e-48
LPKPLPPA_00436 4.5e-36 K Acetyltransferase (GNAT) domain
LPKPLPPA_00437 1.2e-22 K Acetyltransferase (GNAT) domain
LPKPLPPA_00438 1.9e-152 S Protein of unknown function (DUF2785)
LPKPLPPA_00439 1.6e-48 S MazG-like family
LPKPLPPA_00440 2.1e-63
LPKPLPPA_00441 1.4e-135
LPKPLPPA_00443 7.2e-68
LPKPLPPA_00444 4.6e-64 S Domain of unknown function DUF1828
LPKPLPPA_00445 3.1e-77 S Rib/alpha-like repeat
LPKPLPPA_00446 7.7e-247 yagE E amino acid
LPKPLPPA_00447 1.5e-115 GM NmrA-like family
LPKPLPPA_00448 2.8e-87 dedA 3.1.3.1 S SNARE associated Golgi protein
LPKPLPPA_00449 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
LPKPLPPA_00450 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LPKPLPPA_00451 3.9e-240 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LPKPLPPA_00452 0.0 oatA I Acyltransferase
LPKPLPPA_00453 1.4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LPKPLPPA_00454 9.3e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LPKPLPPA_00455 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
LPKPLPPA_00456 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LPKPLPPA_00457 8.1e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LPKPLPPA_00458 2.1e-28 S Protein of unknown function (DUF2929)
LPKPLPPA_00459 0.0 dnaE 2.7.7.7 L DNA polymerase
LPKPLPPA_00461 2.7e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LPKPLPPA_00462 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LPKPLPPA_00463 1.5e-166 cvfB S S1 domain
LPKPLPPA_00464 2.5e-169 xerD D recombinase XerD
LPKPLPPA_00465 3.2e-62 ribT K acetyltransferase
LPKPLPPA_00466 1.1e-135 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LPKPLPPA_00467 2.9e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LPKPLPPA_00468 1.8e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LPKPLPPA_00469 1.9e-58 M Lysin motif
LPKPLPPA_00470 4.4e-98 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LPKPLPPA_00471 2e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LPKPLPPA_00472 2.3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
LPKPLPPA_00473 9.4e-242 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LPKPLPPA_00474 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LPKPLPPA_00475 1.1e-231 S Tetratricopeptide repeat protein
LPKPLPPA_00476 0.0 KL domain protein
LPKPLPPA_00477 2.6e-134
LPKPLPPA_00478 1.8e-292 hsdM 2.1.1.72 V type I restriction-modification system
LPKPLPPA_00479 1.6e-224 3.1.21.3 V Type I restriction modification DNA specificity domain
LPKPLPPA_00480 2.4e-178 L Belongs to the 'phage' integrase family
LPKPLPPA_00481 1.3e-209 3.1.21.3 V Type I restriction modification DNA specificity domain
LPKPLPPA_00482 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
LPKPLPPA_00483 3e-34 ykzG S Belongs to the UPF0356 family
LPKPLPPA_00484 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LPKPLPPA_00485 9.9e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LPKPLPPA_00486 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LPKPLPPA_00487 5.1e-116 S Repeat protein
LPKPLPPA_00488 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
LPKPLPPA_00489 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LPKPLPPA_00490 1.6e-57 XK27_04120 S Putative amino acid metabolism
LPKPLPPA_00491 3.3e-214 iscS 2.8.1.7 E Aminotransferase class V
LPKPLPPA_00492 1.6e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LPKPLPPA_00494 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
LPKPLPPA_00495 2e-32 cspA K 'Cold-shock' DNA-binding domain
LPKPLPPA_00496 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LPKPLPPA_00497 2.1e-119 gpsB D DivIVA domain protein
LPKPLPPA_00498 4.8e-148 ylmH S S4 domain protein
LPKPLPPA_00499 2e-27 yggT S YGGT family
LPKPLPPA_00500 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LPKPLPPA_00501 3.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LPKPLPPA_00502 4.1e-240 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LPKPLPPA_00503 6.3e-154 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LPKPLPPA_00504 1.2e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LPKPLPPA_00505 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LPKPLPPA_00506 1.6e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LPKPLPPA_00507 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LPKPLPPA_00508 6.3e-55 ftsL D Cell division protein FtsL
LPKPLPPA_00509 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LPKPLPPA_00510 4.1e-77 mraZ K Belongs to the MraZ family
LPKPLPPA_00511 3.9e-51 S Protein of unknown function (DUF3397)
LPKPLPPA_00512 3.6e-13 S Protein of unknown function (DUF4044)
LPKPLPPA_00513 5.4e-95 mreD
LPKPLPPA_00514 1e-143 mreC M Involved in formation and maintenance of cell shape
LPKPLPPA_00515 6.4e-166 mreB D cell shape determining protein MreB
LPKPLPPA_00516 3.6e-111 radC L DNA repair protein
LPKPLPPA_00517 9.2e-124 S Haloacid dehalogenase-like hydrolase
LPKPLPPA_00518 2.8e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LPKPLPPA_00519 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LPKPLPPA_00520 0.0 3.6.3.8 P P-type ATPase
LPKPLPPA_00521 5.8e-55 3.6.3.8 P P-type ATPase
LPKPLPPA_00522 4.2e-211 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
LPKPLPPA_00523 2.9e-125 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LPKPLPPA_00524 5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LPKPLPPA_00525 7.8e-216 iscS2 2.8.1.7 E Aminotransferase class V
LPKPLPPA_00526 1.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LPKPLPPA_00527 4.6e-134 cobB K SIR2 family
LPKPLPPA_00528 6.7e-81
LPKPLPPA_00529 6.4e-273 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LPKPLPPA_00530 5.6e-124 yugP S Putative neutral zinc metallopeptidase
LPKPLPPA_00531 6.3e-176 S Alpha/beta hydrolase of unknown function (DUF915)
LPKPLPPA_00532 6.2e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LPKPLPPA_00533 2.4e-162 ypuA S Protein of unknown function (DUF1002)
LPKPLPPA_00534 2.2e-143 2.4.1.293 GT2 M Glycosyltransferase like family 2
LPKPLPPA_00535 6.9e-124 S Alpha/beta hydrolase family
LPKPLPPA_00536 1.4e-62
LPKPLPPA_00537 4.1e-181 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPKPLPPA_00538 2.4e-220 S CAAX protease self-immunity
LPKPLPPA_00539 2.8e-241 cycA E Amino acid permease
LPKPLPPA_00540 6.4e-114 luxT K Bacterial regulatory proteins, tetR family
LPKPLPPA_00541 1.1e-139
LPKPLPPA_00542 7.2e-286 S Cysteine-rich secretory protein family
LPKPLPPA_00543 2.8e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LPKPLPPA_00544 3.3e-95
LPKPLPPA_00545 6.5e-117 yjcE P Sodium proton antiporter
LPKPLPPA_00546 1.3e-141 yjcE P Sodium proton antiporter
LPKPLPPA_00547 1.4e-187 yibE S overlaps another CDS with the same product name
LPKPLPPA_00548 4.9e-118 yibF S overlaps another CDS with the same product name
LPKPLPPA_00549 7.6e-157 I alpha/beta hydrolase fold
LPKPLPPA_00550 0.0 G Belongs to the glycosyl hydrolase 31 family
LPKPLPPA_00551 5.3e-130 XK27_08435 K UTRA
LPKPLPPA_00552 2.4e-217 agaS G SIS domain
LPKPLPPA_00553 1.8e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LPKPLPPA_00554 3.3e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
LPKPLPPA_00555 2.9e-141 XK27_08455 G PTS system sorbose-specific iic component
LPKPLPPA_00556 5.5e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
LPKPLPPA_00557 9.3e-68 2.7.1.191 G PTS system fructose IIA component
LPKPLPPA_00558 1.3e-18 S PD-(D/E)XK nuclease family transposase
LPKPLPPA_00559 2.7e-296 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LPKPLPPA_00560 8.9e-192 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LPKPLPPA_00561 4.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LPKPLPPA_00562 0.0 S membrane
LPKPLPPA_00563 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LPKPLPPA_00564 2.4e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LPKPLPPA_00565 9.9e-61 yabR J S1 RNA binding domain
LPKPLPPA_00566 2.3e-60 divIC D Septum formation initiator
LPKPLPPA_00567 1.8e-34 yabO J S4 domain protein
LPKPLPPA_00568 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LPKPLPPA_00569 3.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LPKPLPPA_00570 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LPKPLPPA_00571 2.4e-124 S (CBS) domain
LPKPLPPA_00572 1.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LPKPLPPA_00573 5.9e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LPKPLPPA_00574 7.7e-261 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LPKPLPPA_00575 2.9e-262 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LPKPLPPA_00576 8e-41 rpmE2 J Ribosomal protein L31
LPKPLPPA_00577 3.2e-284 ybeC E amino acid
LPKPLPPA_00578 3.4e-135 XK27_08845 S ABC transporter, ATP-binding protein
LPKPLPPA_00579 4.9e-141 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
LPKPLPPA_00580 1e-187 ABC-SBP S ABC transporter
LPKPLPPA_00581 0.0 rafA 3.2.1.22 G alpha-galactosidase
LPKPLPPA_00582 2e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LPKPLPPA_00583 6.3e-122 pipD E Dipeptidase
LPKPLPPA_00584 6.3e-63 pipD E Dipeptidase
LPKPLPPA_00585 9.3e-08
LPKPLPPA_00586 6e-79
LPKPLPPA_00587 4.9e-67 S Putative adhesin
LPKPLPPA_00588 5e-79 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LPKPLPPA_00589 3.6e-78 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LPKPLPPA_00590 2.4e-22 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LPKPLPPA_00591 7.1e-40
LPKPLPPA_00592 8.6e-186 yfdV S Membrane transport protein
LPKPLPPA_00593 2.6e-43 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
LPKPLPPA_00594 2.3e-278 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
LPKPLPPA_00595 1.8e-272 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LPKPLPPA_00596 1.3e-93
LPKPLPPA_00597 3.9e-98 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LPKPLPPA_00598 3.1e-58 yjdF S Protein of unknown function (DUF2992)
LPKPLPPA_00599 2.1e-50 S Domain of unknown function (DUF4160)
LPKPLPPA_00600 7.9e-51
LPKPLPPA_00602 5.7e-44 yjdF S Protein of unknown function (DUF2992)
LPKPLPPA_00603 1.8e-112 1.6.5.2 S Flavodoxin-like fold
LPKPLPPA_00604 6.5e-93 K Bacterial regulatory proteins, tetR family
LPKPLPPA_00605 2.4e-66 doc S Fic/DOC family
LPKPLPPA_00606 4.1e-37
LPKPLPPA_00607 1.2e-132 K Helix-turn-helix
LPKPLPPA_00609 1.6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LPKPLPPA_00610 6.6e-134 K DNA-binding helix-turn-helix protein
LPKPLPPA_00611 5.3e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LPKPLPPA_00612 6e-236 pbuX F xanthine permease
LPKPLPPA_00613 2.2e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LPKPLPPA_00614 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LPKPLPPA_00615 2.9e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LPKPLPPA_00616 6e-73 S Domain of unknown function (DUF1934)
LPKPLPPA_00617 3.3e-266 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
LPKPLPPA_00618 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
LPKPLPPA_00619 9.7e-155 malG P ABC transporter permease
LPKPLPPA_00620 6.5e-254 malF P Binding-protein-dependent transport system inner membrane component
LPKPLPPA_00621 5e-229 malE G Bacterial extracellular solute-binding protein
LPKPLPPA_00622 3.6e-210 msmX P Belongs to the ABC transporter superfamily
LPKPLPPA_00623 2.4e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
LPKPLPPA_00624 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
LPKPLPPA_00625 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
LPKPLPPA_00626 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
LPKPLPPA_00627 2.2e-176 yvdE K helix_turn _helix lactose operon repressor
LPKPLPPA_00628 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LPKPLPPA_00629 6.9e-219 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LPKPLPPA_00630 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LPKPLPPA_00631 7.4e-36 veg S Biofilm formation stimulator VEG
LPKPLPPA_00632 1.2e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LPKPLPPA_00633 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LPKPLPPA_00634 2e-146 tatD L hydrolase, TatD family
LPKPLPPA_00635 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LPKPLPPA_00636 3e-91 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
LPKPLPPA_00637 5.2e-99 S TPM domain
LPKPLPPA_00638 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
LPKPLPPA_00639 5.7e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
LPKPLPPA_00640 8.6e-113 E Belongs to the SOS response-associated peptidase family
LPKPLPPA_00642 1.1e-113
LPKPLPPA_00643 5.2e-156 ypbG 2.7.1.2 GK ROK family
LPKPLPPA_00644 4.4e-282 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LPKPLPPA_00645 2.9e-268 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPKPLPPA_00646 3.4e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
LPKPLPPA_00647 1.3e-38
LPKPLPPA_00648 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
LPKPLPPA_00649 3.4e-132 gmuR K UTRA
LPKPLPPA_00650 4.7e-116 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LPKPLPPA_00651 1.4e-166 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LPKPLPPA_00652 1.2e-42 yydK K UTRA
LPKPLPPA_00653 4e-41 yydK K UTRA
LPKPLPPA_00654 1.4e-248 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPKPLPPA_00655 3.7e-82
LPKPLPPA_00656 7.6e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LPKPLPPA_00657 2.1e-76 hsp O Belongs to the small heat shock protein (HSP20) family
LPKPLPPA_00658 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LPKPLPPA_00659 7.7e-43
LPKPLPPA_00660 8.1e-76 pepC 3.4.22.40 E aminopeptidase
LPKPLPPA_00661 8.4e-173 pepC 3.4.22.40 E aminopeptidase
LPKPLPPA_00662 7.5e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LPKPLPPA_00663 3.7e-262 pepC 3.4.22.40 E aminopeptidase
LPKPLPPA_00665 2.8e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LPKPLPPA_00666 1e-76 M Protein of unknown function (DUF3737)
LPKPLPPA_00667 1.8e-80 patB 4.4.1.8 E Aminotransferase, class I
LPKPLPPA_00668 2.9e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
LPKPLPPA_00669 9.2e-68 S SdpI/YhfL protein family
LPKPLPPA_00670 9e-130 K Transcriptional regulatory protein, C terminal
LPKPLPPA_00671 5.3e-270 T PhoQ Sensor
LPKPLPPA_00672 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LPKPLPPA_00673 1.4e-107 vanZ V VanZ like family
LPKPLPPA_00674 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
LPKPLPPA_00675 6.8e-206 EGP Major facilitator Superfamily
LPKPLPPA_00676 1.4e-72
LPKPLPPA_00679 7.2e-197 ampC V Beta-lactamase
LPKPLPPA_00680 4.9e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
LPKPLPPA_00681 5.5e-112 tdk 2.7.1.21 F thymidine kinase
LPKPLPPA_00682 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LPKPLPPA_00683 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LPKPLPPA_00684 1.2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LPKPLPPA_00685 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LPKPLPPA_00686 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
LPKPLPPA_00687 2.1e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPKPLPPA_00688 5.9e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LPKPLPPA_00689 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LPKPLPPA_00690 5.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LPKPLPPA_00691 2.7e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LPKPLPPA_00692 4.3e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LPKPLPPA_00693 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LPKPLPPA_00694 2e-30 ywzB S Protein of unknown function (DUF1146)
LPKPLPPA_00695 2.2e-179 mbl D Cell shape determining protein MreB Mrl
LPKPLPPA_00696 2.5e-15 S DNA-directed RNA polymerase subunit beta
LPKPLPPA_00697 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LPKPLPPA_00698 1.3e-34 S Protein of unknown function (DUF2969)
LPKPLPPA_00699 1.5e-222 rodA D Belongs to the SEDS family
LPKPLPPA_00700 5.2e-81 usp6 T universal stress protein
LPKPLPPA_00702 7.4e-239 rarA L recombination factor protein RarA
LPKPLPPA_00703 1e-81 yueI S Protein of unknown function (DUF1694)
LPKPLPPA_00704 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LPKPLPPA_00707 2.2e-102 3.6.1.27 I Acid phosphatase homologues
LPKPLPPA_00708 8.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LPKPLPPA_00709 3.7e-18 S Sugar efflux transporter for intercellular exchange
LPKPLPPA_00710 1.1e-310 ybiT S ABC transporter, ATP-binding protein
LPKPLPPA_00711 2.7e-41 K Helix-turn-helix domain
LPKPLPPA_00712 2.8e-146 F DNA/RNA non-specific endonuclease
LPKPLPPA_00713 7.6e-60 L nuclease
LPKPLPPA_00714 1.8e-156 metQ1 P Belongs to the nlpA lipoprotein family
LPKPLPPA_00715 8.2e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LPKPLPPA_00716 2.8e-67 metI P ABC transporter permease
LPKPLPPA_00717 3.8e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LPKPLPPA_00718 2.1e-260 frdC 1.3.5.4 C FAD binding domain
LPKPLPPA_00719 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LPKPLPPA_00720 2.9e-257 yjjP S Putative threonine/serine exporter
LPKPLPPA_00721 2.5e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
LPKPLPPA_00722 0.0 aha1 P E1-E2 ATPase
LPKPLPPA_00723 0.0 S Bacterial membrane protein, YfhO
LPKPLPPA_00724 3e-87 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LPKPLPPA_00725 4.6e-174 prmA J Ribosomal protein L11 methyltransferase
LPKPLPPA_00726 1.4e-65
LPKPLPPA_00727 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LPKPLPPA_00728 7.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LPKPLPPA_00729 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
LPKPLPPA_00730 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LPKPLPPA_00731 3.1e-73
LPKPLPPA_00732 1.5e-82 mutT 3.6.1.55 F NUDIX domain
LPKPLPPA_00733 4.6e-35
LPKPLPPA_00734 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LPKPLPPA_00735 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LPKPLPPA_00736 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LPKPLPPA_00737 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LPKPLPPA_00738 2.2e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LPKPLPPA_00739 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
LPKPLPPA_00740 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LPKPLPPA_00741 5.6e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LPKPLPPA_00742 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LPKPLPPA_00743 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LPKPLPPA_00744 3.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LPKPLPPA_00745 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LPKPLPPA_00746 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
LPKPLPPA_00747 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LPKPLPPA_00748 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LPKPLPPA_00749 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LPKPLPPA_00750 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LPKPLPPA_00751 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LPKPLPPA_00752 2.7e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LPKPLPPA_00753 5e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LPKPLPPA_00754 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LPKPLPPA_00755 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LPKPLPPA_00756 1.4e-23 rpmD J Ribosomal protein L30
LPKPLPPA_00757 1.3e-70 rplO J Binds to the 23S rRNA
LPKPLPPA_00758 1.3e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LPKPLPPA_00759 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LPKPLPPA_00760 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LPKPLPPA_00761 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LPKPLPPA_00762 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LPKPLPPA_00763 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LPKPLPPA_00764 1.3e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPKPLPPA_00765 1.3e-61 rplQ J Ribosomal protein L17
LPKPLPPA_00766 5.1e-156 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPKPLPPA_00767 2.2e-162 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPKPLPPA_00768 1.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LPKPLPPA_00769 4.2e-152 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LPKPLPPA_00770 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LPKPLPPA_00771 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
LPKPLPPA_00772 1.2e-79
LPKPLPPA_00773 1.2e-160 1.6.5.2 GM NmrA-like family
LPKPLPPA_00774 3.8e-110 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
LPKPLPPA_00775 1.3e-128 pgm3 G Belongs to the phosphoglycerate mutase family
LPKPLPPA_00776 2.6e-52 K Transcriptional regulator, ArsR family
LPKPLPPA_00777 3.4e-155 czcD P cation diffusion facilitator family transporter
LPKPLPPA_00778 2e-42
LPKPLPPA_00779 5.4e-26
LPKPLPPA_00780 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LPKPLPPA_00781 2.9e-148 dkg S reductase
LPKPLPPA_00782 2.2e-122 endA F DNA RNA non-specific endonuclease
LPKPLPPA_00783 4.3e-280 pipD E Dipeptidase
LPKPLPPA_00784 7.1e-203 malK P ATPases associated with a variety of cellular activities
LPKPLPPA_00785 9.5e-158 gtsB P ABC-type sugar transport systems, permease components
LPKPLPPA_00786 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
LPKPLPPA_00787 7.9e-257 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
LPKPLPPA_00788 3e-240 G Bacterial extracellular solute-binding protein
LPKPLPPA_00789 8.7e-52 ypaA S Protein of unknown function (DUF1304)
LPKPLPPA_00790 1.1e-77 yybA 2.3.1.57 K Transcriptional regulator
LPKPLPPA_00791 6.6e-96 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
LPKPLPPA_00792 1.4e-80 yjcF S Acetyltransferase (GNAT) domain
LPKPLPPA_00793 5.4e-167 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
LPKPLPPA_00794 1.4e-167 3.5.2.6 V Beta-lactamase enzyme family
LPKPLPPA_00795 3e-90 yobS K Bacterial regulatory proteins, tetR family
LPKPLPPA_00796 0.0 ydgH S MMPL family
LPKPLPPA_00797 3.4e-133 cof S haloacid dehalogenase-like hydrolase
LPKPLPPA_00798 2.1e-123 S SNARE associated Golgi protein
LPKPLPPA_00799 6e-180
LPKPLPPA_00800 7.2e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
LPKPLPPA_00801 5.8e-144 hipB K Helix-turn-helix
LPKPLPPA_00802 3.5e-151 I alpha/beta hydrolase fold
LPKPLPPA_00803 1.5e-106 yjbF S SNARE associated Golgi protein
LPKPLPPA_00804 1.1e-101 J Acetyltransferase (GNAT) domain
LPKPLPPA_00805 1.4e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LPKPLPPA_00806 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LPKPLPPA_00807 9.1e-12 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LPKPLPPA_00808 2e-100 nusG K Participates in transcription elongation, termination and antitermination
LPKPLPPA_00809 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LPKPLPPA_00810 1.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LPKPLPPA_00811 4.6e-109 glnP P ABC transporter permease
LPKPLPPA_00812 8.8e-116 glnQ 3.6.3.21 E ABC transporter
LPKPLPPA_00813 6.2e-148 aatB ET ABC transporter substrate-binding protein
LPKPLPPA_00814 3.1e-96 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LPKPLPPA_00815 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LPKPLPPA_00816 1.8e-148 kcsA P Ion transport protein
LPKPLPPA_00817 1.6e-32
LPKPLPPA_00818 3.9e-113 rsmC 2.1.1.172 J Methyltransferase
LPKPLPPA_00819 1.9e-23
LPKPLPPA_00820 8.4e-81 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LPKPLPPA_00821 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LPKPLPPA_00822 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LPKPLPPA_00823 6.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LPKPLPPA_00824 6.9e-26 S Protein of unknown function (DUF2508)
LPKPLPPA_00825 3.7e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LPKPLPPA_00826 4.5e-52 yaaQ S Cyclic-di-AMP receptor
LPKPLPPA_00827 2.8e-154 holB 2.7.7.7 L DNA polymerase III
LPKPLPPA_00828 1.3e-57 yabA L Involved in initiation control of chromosome replication
LPKPLPPA_00829 1.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LPKPLPPA_00830 8.1e-126 fat 3.1.2.21 I Acyl-ACP thioesterase
LPKPLPPA_00831 9.8e-86 folT S ECF transporter, substrate-specific component
LPKPLPPA_00832 1.5e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
LPKPLPPA_00833 2.4e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
LPKPLPPA_00834 2.1e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LPKPLPPA_00835 4.3e-09 D nuclear chromosome segregation
LPKPLPPA_00836 8.4e-10 D nuclear chromosome segregation
LPKPLPPA_00837 3.8e-170
LPKPLPPA_00838 2.7e-114
LPKPLPPA_00839 6.7e-240 clcA P chloride
LPKPLPPA_00840 4.5e-48
LPKPLPPA_00841 2.1e-99 S Protein of unknown function (DUF3990)
LPKPLPPA_00842 2e-158 ykuT M mechanosensitive ion channel
LPKPLPPA_00843 5.9e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LPKPLPPA_00844 2.2e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LPKPLPPA_00845 6.5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LPKPLPPA_00846 2.4e-68 yslB S Protein of unknown function (DUF2507)
LPKPLPPA_00847 6.6e-53 trxA O Belongs to the thioredoxin family
LPKPLPPA_00848 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LPKPLPPA_00849 1.6e-91 cvpA S Colicin V production protein
LPKPLPPA_00850 1.8e-50 yrzB S Belongs to the UPF0473 family
LPKPLPPA_00851 1.4e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LPKPLPPA_00852 2.6e-42 yrzL S Belongs to the UPF0297 family
LPKPLPPA_00853 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LPKPLPPA_00854 1.5e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LPKPLPPA_00855 2.5e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
LPKPLPPA_00856 1.4e-209 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LPKPLPPA_00857 1.4e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LPKPLPPA_00858 4.5e-31 yajC U Preprotein translocase
LPKPLPPA_00859 1.4e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LPKPLPPA_00860 1.6e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LPKPLPPA_00861 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LPKPLPPA_00862 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LPKPLPPA_00863 0.0 nisT V ABC transporter
LPKPLPPA_00864 3e-116 ywnB S NAD(P)H-binding
LPKPLPPA_00865 4.6e-224 S Sterol carrier protein domain
LPKPLPPA_00867 4.9e-201 S Aldo keto reductase
LPKPLPPA_00868 1.3e-85 S Protein of unknown function (DUF3278)
LPKPLPPA_00869 1.2e-20 WQ51_00220 K Helix-turn-helix XRE-family like proteins
LPKPLPPA_00870 7.9e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
LPKPLPPA_00872 3.9e-117 yhiD S MgtC family
LPKPLPPA_00873 0.0
LPKPLPPA_00874 4.5e-70 I Protein of unknown function (DUF2974)
LPKPLPPA_00875 1.6e-131 I Protein of unknown function (DUF2974)
LPKPLPPA_00876 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
LPKPLPPA_00877 1.1e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LPKPLPPA_00878 4.8e-76 rplI J Binds to the 23S rRNA
LPKPLPPA_00879 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LPKPLPPA_00880 1.6e-155 corA P CorA-like Mg2+ transporter protein
LPKPLPPA_00881 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LPKPLPPA_00882 1.7e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LPKPLPPA_00883 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
LPKPLPPA_00884 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LPKPLPPA_00885 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LPKPLPPA_00886 5.1e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LPKPLPPA_00887 1.6e-185 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
LPKPLPPA_00888 0.0 L AAA domain
LPKPLPPA_00889 1.6e-230 yhaO L Ser Thr phosphatase family protein
LPKPLPPA_00890 3.3e-56 yheA S Belongs to the UPF0342 family
LPKPLPPA_00891 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LPKPLPPA_00892 3.6e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LPKPLPPA_00894 1.3e-259 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
LPKPLPPA_00895 1.3e-66
LPKPLPPA_00896 2e-94 3.6.1.55 L NUDIX domain
LPKPLPPA_00897 1.4e-152 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
LPKPLPPA_00898 3.9e-198 V Beta-lactamase
LPKPLPPA_00899 8.4e-63
LPKPLPPA_00900 0.0 L helicase activity
LPKPLPPA_00901 6.4e-227 K DNA binding
LPKPLPPA_00902 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
LPKPLPPA_00903 2.2e-247 mod 2.1.1.72, 3.1.21.5 L DNA methylase
LPKPLPPA_00904 7.4e-39 K Cro/C1-type HTH DNA-binding domain
LPKPLPPA_00905 1.1e-77
LPKPLPPA_00906 2.5e-114
LPKPLPPA_00907 2.6e-61
LPKPLPPA_00908 3.2e-36
LPKPLPPA_00909 1.3e-232
LPKPLPPA_00911 2.7e-23
LPKPLPPA_00912 4.9e-51
LPKPLPPA_00913 6.1e-221 L Protein of unknown function (DUF2800)
LPKPLPPA_00914 1.7e-99 S Protein of unknown function (DUF2815)
LPKPLPPA_00915 0.0 polA_2 2.7.7.7 L DNA polymerase
LPKPLPPA_00916 2.8e-69 S Psort location Cytoplasmic, score
LPKPLPPA_00917 0.0 S Phage plasmid primase, P4
LPKPLPPA_00918 2.4e-46 S VRR_NUC
LPKPLPPA_00919 4.3e-258 L SNF2 family N-terminal domain
LPKPLPPA_00920 2.8e-87
LPKPLPPA_00921 1.4e-36
LPKPLPPA_00922 2.2e-245 2.1.1.72 KL DNA methylase
LPKPLPPA_00923 3.5e-52 S Psort location Cytoplasmic, score
LPKPLPPA_00924 6.2e-31 S Domain of unknown function (DUF5049)
LPKPLPPA_00925 2.6e-302 S overlaps another CDS with the same product name
LPKPLPPA_00926 2.5e-247 S Phage portal protein
LPKPLPPA_00927 2.9e-122 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
LPKPLPPA_00928 4.1e-220 S Phage capsid family
LPKPLPPA_00929 4.3e-43 S Phage gp6-like head-tail connector protein
LPKPLPPA_00930 9e-68 S Phage head-tail joining protein
LPKPLPPA_00931 3e-69 S Bacteriophage holin family
LPKPLPPA_00932 2.5e-145 M Glycosyl hydrolases family 25
LPKPLPPA_00933 4.3e-36
LPKPLPPA_00934 3.1e-164 L Recombinase zinc beta ribbon domain
LPKPLPPA_00935 9.1e-101 L Recombinase zinc beta ribbon domain
LPKPLPPA_00936 1.2e-288 L Recombinase
LPKPLPPA_00937 2.7e-227
LPKPLPPA_00938 8.7e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LPKPLPPA_00939 9.6e-121 spaE S ABC-2 family transporter protein
LPKPLPPA_00940 1.6e-108 mutF V ABC transporter, ATP-binding protein
LPKPLPPA_00941 1.3e-241 nhaC C Na H antiporter NhaC
LPKPLPPA_00942 6.2e-162 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
LPKPLPPA_00943 3.3e-95 S UPF0397 protein
LPKPLPPA_00944 0.0 ykoD P ABC transporter, ATP-binding protein
LPKPLPPA_00945 3.1e-142 cbiQ P cobalt transport
LPKPLPPA_00946 2.7e-118 ybhL S Belongs to the BI1 family
LPKPLPPA_00947 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
LPKPLPPA_00948 4.7e-64 S Domain of unknown function (DUF4430)
LPKPLPPA_00949 8.1e-88 S ECF transporter, substrate-specific component
LPKPLPPA_00950 2.1e-94 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
LPKPLPPA_00951 1.7e-128 L Helix-turn-helix domain
LPKPLPPA_00952 2.3e-23 L hmm pf00665
LPKPLPPA_00953 1.2e-39 L hmm pf00665
LPKPLPPA_00954 9.6e-152 S hydrolase
LPKPLPPA_00956 7.3e-169 yegS 2.7.1.107 G Lipid kinase
LPKPLPPA_00957 1.5e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LPKPLPPA_00958 1.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LPKPLPPA_00959 4.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LPKPLPPA_00960 1.7e-207 camS S sex pheromone
LPKPLPPA_00961 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LPKPLPPA_00962 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LPKPLPPA_00963 2.7e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
LPKPLPPA_00964 1.3e-100 S ECF transporter, substrate-specific component
LPKPLPPA_00966 7.4e-85 ydcK S Belongs to the SprT family
LPKPLPPA_00967 7e-135 M Glycosyltransferase sugar-binding region containing DXD motif
LPKPLPPA_00968 1.9e-256 epsU S Polysaccharide biosynthesis protein
LPKPLPPA_00969 4.7e-229 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LPKPLPPA_00970 7e-147
LPKPLPPA_00971 4.8e-102 V ABC transporter transmembrane region
LPKPLPPA_00972 4.9e-148 V ABC transporter transmembrane region
LPKPLPPA_00973 0.0 pacL 3.6.3.8 P P-type ATPase
LPKPLPPA_00974 3.6e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LPKPLPPA_00975 2.9e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LPKPLPPA_00976 0.0 tuaG GT2 M Glycosyltransferase like family 2
LPKPLPPA_00977 2.9e-204 csaB M Glycosyl transferases group 1
LPKPLPPA_00978 4.2e-141 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LPKPLPPA_00979 1.5e-67 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
LPKPLPPA_00980 4.7e-123 gntR1 K UTRA
LPKPLPPA_00981 9.3e-190
LPKPLPPA_00982 1.4e-52 P Rhodanese Homology Domain
LPKPLPPA_00985 9.9e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
LPKPLPPA_00986 1.8e-145 K SIS domain
LPKPLPPA_00987 4.2e-08 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
LPKPLPPA_00988 7e-295 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LPKPLPPA_00989 9.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LPKPLPPA_00990 1.7e-123 liaI S membrane
LPKPLPPA_00991 1e-78 XK27_02470 K LytTr DNA-binding domain
LPKPLPPA_00992 3e-104 yvdD 3.2.2.10 S Belongs to the LOG family
LPKPLPPA_00993 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LPKPLPPA_00994 0.0 uup S ABC transporter, ATP-binding protein
LPKPLPPA_00995 8.3e-68
LPKPLPPA_00996 9.3e-155 K Helix-turn-helix XRE-family like proteins
LPKPLPPA_00997 7.6e-249 scrB 2.7.1.211, 3.2.1.26 GH32 G Glycosyl hydrolases family 32
LPKPLPPA_00998 2.9e-40 scrB 2.7.1.211, 3.2.1.26 GH32 G Glycosyl hydrolases family 32
LPKPLPPA_00999 0.0 scrA 2.7.1.211 G phosphotransferase system
LPKPLPPA_01000 2.7e-188 bglX 3.2.1.21 GH3 G hydrolase, family 3
LPKPLPPA_01001 1.1e-228 bglX 3.2.1.21 GH3 G hydrolase, family 3
LPKPLPPA_01002 6.3e-193 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LPKPLPPA_01003 3.3e-228 G Major Facilitator Superfamily
LPKPLPPA_01004 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LPKPLPPA_01005 1.7e-210 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LPKPLPPA_01006 1.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
LPKPLPPA_01007 1.7e-34
LPKPLPPA_01008 4.2e-98 yvrI K sigma factor activity
LPKPLPPA_01009 5.3e-291 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
LPKPLPPA_01010 8.3e-291 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
LPKPLPPA_01011 1.9e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
LPKPLPPA_01012 2e-152 lacT K PRD domain
LPKPLPPA_01013 1.2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPKPLPPA_01014 1.7e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LPKPLPPA_01015 3.4e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LPKPLPPA_01016 3.1e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LPKPLPPA_01017 1.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LPKPLPPA_01018 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
LPKPLPPA_01019 2.1e-257 pepC 3.4.22.40 E Peptidase C1-like family
LPKPLPPA_01020 2.6e-185 S AAA domain
LPKPLPPA_01021 2.6e-98 K LysR substrate binding domain
LPKPLPPA_01022 4.2e-177 lacX 5.1.3.3 G Aldose 1-epimerase
LPKPLPPA_01023 8.2e-252 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LPKPLPPA_01024 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LPKPLPPA_01025 2e-169 xerC D Phage integrase, N-terminal SAM-like domain
LPKPLPPA_01026 2.7e-244 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LPKPLPPA_01027 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LPKPLPPA_01028 2.6e-152 dprA LU DNA protecting protein DprA
LPKPLPPA_01029 9.8e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LPKPLPPA_01030 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LPKPLPPA_01031 1.1e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
LPKPLPPA_01032 2e-35 yozE S Belongs to the UPF0346 family
LPKPLPPA_01033 3.8e-151 DegV S Uncharacterised protein, DegV family COG1307
LPKPLPPA_01034 7.6e-115 hlyIII S protein, hemolysin III
LPKPLPPA_01035 6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LPKPLPPA_01036 3.8e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LPKPLPPA_01037 9.2e-109
LPKPLPPA_01038 7.2e-92
LPKPLPPA_01039 0.0 1.3.5.4 C FMN_bind
LPKPLPPA_01040 1.7e-165 S Protein of unknown function DUF262
LPKPLPPA_01041 2.2e-229 XK27_04775 S PAS domain
LPKPLPPA_01042 6.4e-105 S Iron-sulfur cluster assembly protein
LPKPLPPA_01043 5.3e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LPKPLPPA_01044 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LPKPLPPA_01045 1.2e-64
LPKPLPPA_01046 7.3e-266 yxbA 6.3.1.12 S ATP-grasp enzyme
LPKPLPPA_01047 0.0 asnB 6.3.5.4 E Asparagine synthase
LPKPLPPA_01048 1.8e-275 S Calcineurin-like phosphoesterase
LPKPLPPA_01049 7.3e-83
LPKPLPPA_01050 5.4e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
LPKPLPPA_01051 1.6e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
LPKPLPPA_01052 4.3e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LPKPLPPA_01053 9.8e-169 phnD P Phosphonate ABC transporter
LPKPLPPA_01055 3.8e-87 uspA T universal stress protein
LPKPLPPA_01056 2e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
LPKPLPPA_01057 4.4e-132 XK27_08440 K UTRA domain
LPKPLPPA_01058 4.9e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LPKPLPPA_01059 7.4e-88 ntd 2.4.2.6 F Nucleoside
LPKPLPPA_01060 1.4e-189
LPKPLPPA_01061 2.3e-207 S zinc-ribbon domain
LPKPLPPA_01063 1.1e-149 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
LPKPLPPA_01064 1.7e-59 yjgN S Bacterial protein of unknown function (DUF898)
LPKPLPPA_01066 3.9e-93 M LysM domain protein
LPKPLPPA_01067 3.9e-110 M LysM domain protein
LPKPLPPA_01068 2.3e-133 S Putative ABC-transporter type IV
LPKPLPPA_01069 5.8e-49 psiE S Phosphate-starvation-inducible E
LPKPLPPA_01070 7.9e-75 K acetyltransferase
LPKPLPPA_01071 2.2e-180 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LPKPLPPA_01072 2.5e-195 G Psort location CytoplasmicMembrane, score 10.00
LPKPLPPA_01073 1.4e-36 licT K CAT RNA binding domain
LPKPLPPA_01074 1e-19 licT K transcriptional antiterminator
LPKPLPPA_01075 4.8e-131 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LPKPLPPA_01076 7.3e-217 L Belongs to the 'phage' integrase family
LPKPLPPA_01077 7.7e-15
LPKPLPPA_01078 9.5e-91 repB EP Plasmid replication protein
LPKPLPPA_01080 1.7e-132 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LPKPLPPA_01081 1.3e-24
LPKPLPPA_01082 2.2e-18 K Helix-turn-helix XRE-family like proteins
LPKPLPPA_01084 5.1e-164 yvgN C Aldo keto reductase
LPKPLPPA_01085 6.8e-248 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
LPKPLPPA_01086 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LPKPLPPA_01087 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LPKPLPPA_01088 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LPKPLPPA_01089 3.8e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LPKPLPPA_01090 2.5e-35
LPKPLPPA_01091 6.2e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LPKPLPPA_01092 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LPKPLPPA_01093 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LPKPLPPA_01094 5.7e-126 comFC S Competence protein
LPKPLPPA_01095 1.1e-242 comFA L Helicase C-terminal domain protein
LPKPLPPA_01096 2.5e-118 yvyE 3.4.13.9 S YigZ family
LPKPLPPA_01097 2.7e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
LPKPLPPA_01098 1.2e-209 rny S Endoribonuclease that initiates mRNA decay
LPKPLPPA_01099 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LPKPLPPA_01100 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LPKPLPPA_01101 4.3e-125 ymfM S Helix-turn-helix domain
LPKPLPPA_01102 1.6e-129 IQ Enoyl-(Acyl carrier protein) reductase
LPKPLPPA_01103 2.9e-232 S Peptidase M16
LPKPLPPA_01104 1.5e-83 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
LPKPLPPA_01105 1.5e-115 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
LPKPLPPA_01109 4.8e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LPKPLPPA_01110 3.2e-259 qacA EGP Major facilitator Superfamily
LPKPLPPA_01111 5.9e-82 3.6.1.27 I Acid phosphatase homologues
LPKPLPPA_01112 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LPKPLPPA_01113 3.9e-301 ytgP S Polysaccharide biosynthesis protein
LPKPLPPA_01114 1.4e-214 I Protein of unknown function (DUF2974)
LPKPLPPA_01115 7.5e-119
LPKPLPPA_01116 4.3e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LPKPLPPA_01117 2.4e-124 M ErfK YbiS YcfS YnhG
LPKPLPPA_01118 6.1e-171 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LPKPLPPA_01119 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LPKPLPPA_01120 6.5e-173 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
LPKPLPPA_01121 2.4e-50
LPKPLPPA_01122 9e-77 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
LPKPLPPA_01123 5.8e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LPKPLPPA_01125 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LPKPLPPA_01126 6e-128 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
LPKPLPPA_01127 1.1e-107 ylbE GM NAD(P)H-binding
LPKPLPPA_01128 6.9e-83 yebR 1.8.4.14 T GAF domain-containing protein
LPKPLPPA_01129 6.1e-154 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LPKPLPPA_01130 8.7e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LPKPLPPA_01131 1.6e-166 yihY S Belongs to the UPF0761 family
LPKPLPPA_01132 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
LPKPLPPA_01133 4.2e-77 fld C Flavodoxin
LPKPLPPA_01134 2e-86 gtcA S Teichoic acid glycosylation protein
LPKPLPPA_01135 6.5e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LPKPLPPA_01138 2.1e-249 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPKPLPPA_01139 4.1e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
LPKPLPPA_01140 2.6e-137 M Glycosyl hydrolases family 25
LPKPLPPA_01141 1.9e-234 potE E amino acid
LPKPLPPA_01142 6.3e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LPKPLPPA_01143 3.6e-252 yhdP S Transporter associated domain
LPKPLPPA_01144 1.1e-132
LPKPLPPA_01145 1.6e-120 C nitroreductase
LPKPLPPA_01146 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
LPKPLPPA_01147 8.9e-139 glcR K DeoR C terminal sensor domain
LPKPLPPA_01148 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LPKPLPPA_01149 4.6e-76 WQ51_03320 S Protein of unknown function (DUF1149)
LPKPLPPA_01150 1.7e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LPKPLPPA_01151 5.4e-212 yubA S AI-2E family transporter
LPKPLPPA_01152 9.9e-67 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
LPKPLPPA_01153 4.8e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
LPKPLPPA_01154 3.9e-234 N Uncharacterized conserved protein (DUF2075)
LPKPLPPA_01155 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
LPKPLPPA_01156 3.7e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LPKPLPPA_01157 5.2e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LPKPLPPA_01158 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
LPKPLPPA_01159 3.3e-112 yjbK S CYTH
LPKPLPPA_01160 7e-107 yjbH Q Thioredoxin
LPKPLPPA_01161 1.7e-162 coiA 3.6.4.12 S Competence protein
LPKPLPPA_01162 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LPKPLPPA_01163 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LPKPLPPA_01164 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LPKPLPPA_01165 1.2e-39 ptsH G phosphocarrier protein HPR
LPKPLPPA_01166 2.8e-113 S domain, Protein
LPKPLPPA_01167 0.0 S domain, Protein
LPKPLPPA_01168 5.3e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LPKPLPPA_01169 5.2e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
LPKPLPPA_01170 6.2e-213 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LPKPLPPA_01171 1e-251 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
LPKPLPPA_01172 3e-166 K AI-2E family transporter
LPKPLPPA_01173 1.8e-40
LPKPLPPA_01174 2.2e-165 S Alpha beta hydrolase
LPKPLPPA_01175 0.0 L Helicase C-terminal domain protein
LPKPLPPA_01176 5.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
LPKPLPPA_01177 2.5e-40 S Transglycosylase associated protein
LPKPLPPA_01179 1.2e-70 P CorA-like Mg2+ transporter protein
LPKPLPPA_01180 8.7e-63 P CorA-like Mg2+ transporter protein
LPKPLPPA_01181 0.0 tetP J elongation factor G
LPKPLPPA_01182 6e-61 yugI 5.3.1.9 J general stress protein
LPKPLPPA_01183 4.8e-179 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
LPKPLPPA_01184 2.7e-117 dedA S SNARE-like domain protein
LPKPLPPA_01185 8.6e-105 S Protein of unknown function (DUF1461)
LPKPLPPA_01186 3.6e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LPKPLPPA_01187 9.1e-98 yutD S Protein of unknown function (DUF1027)
LPKPLPPA_01188 3.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LPKPLPPA_01189 2e-55
LPKPLPPA_01190 8e-268 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LPKPLPPA_01191 2.4e-275 pepV 3.5.1.18 E dipeptidase PepV
LPKPLPPA_01192 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
LPKPLPPA_01193 9.5e-178 ccpA K catabolite control protein A
LPKPLPPA_01194 5.9e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LPKPLPPA_01195 4e-51
LPKPLPPA_01197 4.2e-194 S Bacteriocin helveticin-J
LPKPLPPA_01198 2.1e-105 tag 3.2.2.20 L glycosylase
LPKPLPPA_01199 6.9e-162 mleP3 S Membrane transport protein
LPKPLPPA_01200 2.3e-134 S CAAX amino terminal protease
LPKPLPPA_01201 1.4e-144 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LPKPLPPA_01202 6.4e-255 emrY EGP Major facilitator Superfamily
LPKPLPPA_01203 4.5e-261 emrY EGP Major facilitator Superfamily
LPKPLPPA_01204 4.9e-69 yxdD K Bacterial regulatory proteins, tetR family
LPKPLPPA_01205 0.0 4.2.1.53 S Myosin-crossreactive antigen
LPKPLPPA_01206 1.5e-76 2.3.1.128 K acetyltransferase
LPKPLPPA_01207 5.4e-144 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LPKPLPPA_01208 3.2e-103 yagU S Protein of unknown function (DUF1440)
LPKPLPPA_01209 4.1e-147 S hydrolase
LPKPLPPA_01210 0.0 M domain protein
LPKPLPPA_01211 0.0 bamA UW LPXTG-motif cell wall anchor domain protein
LPKPLPPA_01212 3.9e-23 bamA UW LPXTG-motif cell wall anchor domain protein
LPKPLPPA_01214 0.0 S domain, Protein
LPKPLPPA_01215 0.0 lhr L DEAD DEAH box helicase
LPKPLPPA_01216 5.4e-253 P P-loop Domain of unknown function (DUF2791)
LPKPLPPA_01217 0.0 S TerB-C domain
LPKPLPPA_01218 1.3e-99 4.1.1.44 S decarboxylase
LPKPLPPA_01219 5.1e-72
LPKPLPPA_01220 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LPKPLPPA_01221 4.9e-233 cycA E Amino acid permease
LPKPLPPA_01222 2.4e-108 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
LPKPLPPA_01223 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPKPLPPA_01224 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LPKPLPPA_01225 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LPKPLPPA_01227 1.6e-08
LPKPLPPA_01228 1.2e-63
LPKPLPPA_01229 8.9e-179 MA20_14895 S Conserved hypothetical protein 698
LPKPLPPA_01230 5.9e-70 K Transcriptional regulator
LPKPLPPA_01231 5.4e-47
LPKPLPPA_01232 2.6e-42
LPKPLPPA_01233 1.8e-41 K peptidyl-tyrosine sulfation
LPKPLPPA_01234 1.7e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LPKPLPPA_01235 2e-74 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LPKPLPPA_01237 2.1e-109 ybbL S ABC transporter, ATP-binding protein
LPKPLPPA_01238 2.1e-129 ybbM S Uncharacterised protein family (UPF0014)
LPKPLPPA_01239 9.6e-97 K Acetyltransferase (GNAT) domain
LPKPLPPA_01240 1.4e-50 S Protein of unknown function (DUF3021)
LPKPLPPA_01241 8.7e-75 K LytTr DNA-binding domain
LPKPLPPA_01242 6.2e-104 S Protein of unknown function (DUF1211)
LPKPLPPA_01243 6.7e-153 K helix_turn_helix, arabinose operon control protein
LPKPLPPA_01244 5e-234 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
LPKPLPPA_01245 1.7e-53 S Bacterial toxin of type II toxin-antitoxin system, YafQ
LPKPLPPA_01246 1.2e-48 L bacterial-type proximal promoter sequence-specific DNA binding
LPKPLPPA_01247 2.3e-78 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
LPKPLPPA_01248 1.3e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LPKPLPPA_01249 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LPKPLPPA_01250 1.4e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LPKPLPPA_01251 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LPKPLPPA_01252 4.4e-37 S YtxH-like protein
LPKPLPPA_01253 2e-64
LPKPLPPA_01254 2.4e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
LPKPLPPA_01255 2.4e-133 ecsA V ABC transporter, ATP-binding protein
LPKPLPPA_01256 3.9e-226 ecsB U ABC transporter
LPKPLPPA_01257 1.7e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LPKPLPPA_01258 3.4e-42 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LPKPLPPA_01259 1e-16 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LPKPLPPA_01260 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LPKPLPPA_01261 7e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LPKPLPPA_01262 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
LPKPLPPA_01263 6.6e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LPKPLPPA_01264 3.7e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LPKPLPPA_01265 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LPKPLPPA_01266 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LPKPLPPA_01267 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LPKPLPPA_01268 6.6e-270 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LPKPLPPA_01269 5.8e-291 clcA P chloride
LPKPLPPA_01270 1.2e-201 EGP Major facilitator Superfamily
LPKPLPPA_01271 1.7e-151 ropB K Transcriptional regulator
LPKPLPPA_01272 2.2e-107
LPKPLPPA_01273 1.5e-115 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
LPKPLPPA_01274 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LPKPLPPA_01275 6.5e-69 S Iron-sulphur cluster biosynthesis
LPKPLPPA_01276 2.3e-232 EGP Sugar (and other) transporter
LPKPLPPA_01277 2.3e-75 K Acetyltransferase (GNAT) domain
LPKPLPPA_01278 1e-248 ynbB 4.4.1.1 P aluminum resistance
LPKPLPPA_01279 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
LPKPLPPA_01280 4.1e-286 E Amino acid permease
LPKPLPPA_01281 0.0 pepO 3.4.24.71 O Peptidase family M13
LPKPLPPA_01282 4.4e-155 ropB K Helix-turn-helix XRE-family like proteins
LPKPLPPA_01283 0.0 copA 3.6.3.54 P P-type ATPase
LPKPLPPA_01284 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LPKPLPPA_01285 6.3e-66 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LPKPLPPA_01286 1.4e-77 atkY K Penicillinase repressor
LPKPLPPA_01287 5.5e-90
LPKPLPPA_01288 4.1e-90
LPKPLPPA_01289 3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LPKPLPPA_01290 1.1e-226 pbuG S permease
LPKPLPPA_01291 3.4e-46 I bis(5'-adenosyl)-triphosphatase activity
LPKPLPPA_01292 2.3e-232 pbuG S permease
LPKPLPPA_01293 3.7e-110 K helix_turn_helix, mercury resistance
LPKPLPPA_01295 3e-232 pbuG S permease
LPKPLPPA_01296 6e-238 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
LPKPLPPA_01297 8.2e-125 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LPKPLPPA_01298 7.7e-120 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LPKPLPPA_01299 1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LPKPLPPA_01300 9.8e-160 yeaE S Aldo/keto reductase family
LPKPLPPA_01301 3.6e-19 S PD-(D/E)XK nuclease family transposase
LPKPLPPA_01302 4.6e-150 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
LPKPLPPA_01303 1.1e-91 agaC G PTS system sorbose-specific iic component
LPKPLPPA_01304 1e-121 G PTS system mannose/fructose/sorbose family IID component
LPKPLPPA_01305 2.2e-27 G PTS system fructose IIA component
LPKPLPPA_01306 1.2e-132 S membrane transporter protein
LPKPLPPA_01307 2e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LPKPLPPA_01308 4.1e-130 3.5.2.6 V Beta-lactamase enzyme family
LPKPLPPA_01309 5.7e-189 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LPKPLPPA_01310 3.2e-88 blaA6 V Beta-lactamase
LPKPLPPA_01311 1.3e-52 2.7.1.191 G PTS system sorbose subfamily IIB component
LPKPLPPA_01312 1e-119 G PTS system mannose/fructose/sorbose family IID component
LPKPLPPA_01313 2e-99 G PTS system sorbose-specific iic component
LPKPLPPA_01314 7e-177 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
LPKPLPPA_01315 4.8e-173 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
LPKPLPPA_01316 7.1e-195 tcsA S ABC transporter substrate-binding protein PnrA-like
LPKPLPPA_01317 1.2e-166 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
LPKPLPPA_01318 1.1e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
LPKPLPPA_01319 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LPKPLPPA_01320 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LPKPLPPA_01321 2.2e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
LPKPLPPA_01322 8.7e-270 cydA 1.10.3.14 C ubiquinol oxidase
LPKPLPPA_01323 0.0 macB_3 V ABC transporter, ATP-binding protein
LPKPLPPA_01324 1.5e-195 S DUF218 domain
LPKPLPPA_01325 6.5e-103 S CAAX protease self-immunity
LPKPLPPA_01326 2.2e-93 S Protein of unknown function (DUF1440)
LPKPLPPA_01327 4.5e-269 G PTS system Galactitol-specific IIC component
LPKPLPPA_01328 2.7e-234 G PTS system sugar-specific permease component
LPKPLPPA_01329 2.3e-114 S Protein of unknown function (DUF969)
LPKPLPPA_01330 3.8e-157 S Protein of unknown function (DUF979)
LPKPLPPA_01331 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LPKPLPPA_01332 2.1e-30
LPKPLPPA_01333 4.1e-31
LPKPLPPA_01334 6.2e-28
LPKPLPPA_01335 8.5e-159 mutR K Helix-turn-helix XRE-family like proteins
LPKPLPPA_01336 2.7e-280 V ABC transporter transmembrane region
LPKPLPPA_01338 3.5e-200 napA P Sodium/hydrogen exchanger family
LPKPLPPA_01339 0.0 cadA P P-type ATPase
LPKPLPPA_01340 1.9e-83 ykuL S (CBS) domain
LPKPLPPA_01341 5.9e-19
LPKPLPPA_01342 5.9e-40
LPKPLPPA_01343 6.7e-225 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
LPKPLPPA_01346 7.3e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LPKPLPPA_01347 1.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
LPKPLPPA_01348 4.7e-88 comGF U Putative Competence protein ComGF
LPKPLPPA_01356 4.2e-217 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
LPKPLPPA_01357 3.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
LPKPLPPA_01358 4.5e-183 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LPKPLPPA_01359 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LPKPLPPA_01360 6.2e-80 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
LPKPLPPA_01362 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
LPKPLPPA_01363 7.1e-132 S Protein of unknown function (DUF975)
LPKPLPPA_01364 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LPKPLPPA_01365 5.2e-153 yitS S EDD domain protein, DegV family
LPKPLPPA_01366 2.2e-19
LPKPLPPA_01367 9.3e-54 K Transcriptional regulator
LPKPLPPA_01369 1e-182 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LPKPLPPA_01370 4.4e-139 G Pts system
LPKPLPPA_01371 1.5e-21 K DNA-binding transcription factor activity
LPKPLPPA_01373 5.2e-25 S PFAM Archaeal ATPase
LPKPLPPA_01374 2.1e-241 pyrP F Permease
LPKPLPPA_01375 1.3e-137 lacR K DeoR C terminal sensor domain
LPKPLPPA_01376 9.4e-74 lacA 5.3.1.26 G Ribose/Galactose Isomerase
LPKPLPPA_01377 1.9e-106 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
LPKPLPPA_01378 1.6e-128 S Domain of unknown function (DUF4867)
LPKPLPPA_01379 7.2e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LPKPLPPA_01380 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
LPKPLPPA_01381 1.4e-267 gatC G PTS system sugar-specific permease component
LPKPLPPA_01382 1.3e-38
LPKPLPPA_01383 2.1e-149 lacT K CAT RNA binding domain
LPKPLPPA_01384 8.7e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
LPKPLPPA_01385 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
LPKPLPPA_01386 3.2e-177 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
LPKPLPPA_01387 2.7e-99 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
LPKPLPPA_01388 3e-201 S PFAM Archaeal ATPase
LPKPLPPA_01389 8.2e-165 K LysR family
LPKPLPPA_01390 0.0 1.3.5.4 C FMN_bind
LPKPLPPA_01391 3.7e-260 P Sodium:sulfate symporter transmembrane region
LPKPLPPA_01392 1.2e-83 glsA 3.5.1.2 E Belongs to the glutaminase family
LPKPLPPA_01393 2.1e-67 glsA 3.5.1.2 E Belongs to the glutaminase family
LPKPLPPA_01394 3.3e-112 3.6.1.27 I Acid phosphatase homologues
LPKPLPPA_01395 1.9e-217 mdtG EGP Major facilitator Superfamily
LPKPLPPA_01396 1.5e-32
LPKPLPPA_01397 6.1e-73 K helix_turn_helix multiple antibiotic resistance protein
LPKPLPPA_01398 5.8e-82
LPKPLPPA_01399 2.7e-210 pepA E M42 glutamyl aminopeptidase
LPKPLPPA_01401 5.9e-88 2.7.1.191 G PTS system sorbose subfamily IIB component
LPKPLPPA_01402 4.7e-103 G PTS system sorbose-specific iic component
LPKPLPPA_01403 3.4e-152 G PTS system mannose/fructose/sorbose family IID component
LPKPLPPA_01404 6.8e-72 2.7.1.191 G PTS system fructose IIA component
LPKPLPPA_01405 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
LPKPLPPA_01406 8.2e-182 lacI3 K helix_turn _helix lactose operon repressor
LPKPLPPA_01407 0.0 3.2.1.177 GH31 G Glycosyl hydrolases family 31
LPKPLPPA_01408 1.6e-266 dtpT U amino acid peptide transporter
LPKPLPPA_01409 2.9e-208 naiP EGP Major facilitator Superfamily
LPKPLPPA_01410 7.9e-152 S Alpha beta hydrolase
LPKPLPPA_01411 1.9e-59 K Transcriptional regulator, MarR family
LPKPLPPA_01412 0.0 XK27_09600 V ABC transporter, ATP-binding protein
LPKPLPPA_01413 0.0 V ABC transporter transmembrane region
LPKPLPPA_01414 1.3e-148 glnH ET ABC transporter
LPKPLPPA_01415 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LPKPLPPA_01416 9.1e-150 glnH ET ABC transporter
LPKPLPPA_01417 3.2e-110 gluC P ABC transporter permease
LPKPLPPA_01418 2e-107 glnP P ABC transporter permease
LPKPLPPA_01419 4.8e-151 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LPKPLPPA_01420 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
LPKPLPPA_01421 1.1e-130 treR K UTRA
LPKPLPPA_01422 0.0 treB 2.7.1.211 G phosphotransferase system
LPKPLPPA_01423 8.3e-84 S Putative adhesin
LPKPLPPA_01424 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
LPKPLPPA_01425 1.9e-205 EGP Major facilitator superfamily
LPKPLPPA_01427 6.8e-56 S Enterocin A Immunity
LPKPLPPA_01428 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
LPKPLPPA_01429 4.8e-159 rssA S Phospholipase, patatin family
LPKPLPPA_01430 4.1e-257 glnPH2 P ABC transporter permease
LPKPLPPA_01431 3.8e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LPKPLPPA_01432 6.2e-96 K Acetyltransferase (GNAT) domain
LPKPLPPA_01433 1.3e-159 pstS P Phosphate
LPKPLPPA_01434 2.1e-161 pstC P probably responsible for the translocation of the substrate across the membrane
LPKPLPPA_01435 5.4e-156 pstA P Phosphate transport system permease protein PstA
LPKPLPPA_01436 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LPKPLPPA_01437 2.7e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LPKPLPPA_01438 2.6e-118 phoU P Plays a role in the regulation of phosphate uptake
LPKPLPPA_01439 2.2e-282 S C4-dicarboxylate anaerobic carrier
LPKPLPPA_01440 1.7e-84 dps P Belongs to the Dps family
LPKPLPPA_01442 3.2e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LPKPLPPA_01443 4.8e-128 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LPKPLPPA_01444 4.1e-175 rihB 3.2.2.1 F Nucleoside
LPKPLPPA_01445 4e-133 gntR K UbiC transcription regulator-associated domain protein
LPKPLPPA_01446 2e-52 S Enterocin A Immunity
LPKPLPPA_01447 1.5e-189 L COG2963 Transposase and inactivated derivatives
LPKPLPPA_01449 5e-60
LPKPLPPA_01453 2.8e-31 I Protein of unknown function (DUF2974)
LPKPLPPA_01465 5.6e-149 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LPKPLPPA_01466 6.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LPKPLPPA_01467 4.8e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LPKPLPPA_01468 2.7e-129 ymfC K UTRA
LPKPLPPA_01469 8.2e-254 3.5.1.18 E Peptidase family M20/M25/M40
LPKPLPPA_01470 3.3e-180 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
LPKPLPPA_01471 2.9e-93 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
LPKPLPPA_01472 5.6e-55 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPKPLPPA_01473 4.1e-150 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LPKPLPPA_01474 1.2e-117 cutC P Participates in the control of copper homeostasis
LPKPLPPA_01475 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LPKPLPPA_01476 1.4e-75 K UTRA
LPKPLPPA_01477 5.9e-12
LPKPLPPA_01478 4e-69 rmaI K Transcriptional regulator
LPKPLPPA_01479 1.4e-211 EGP Major facilitator Superfamily
LPKPLPPA_01480 5.7e-230 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
LPKPLPPA_01481 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LPKPLPPA_01482 1.1e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LPKPLPPA_01483 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LPKPLPPA_01484 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LPKPLPPA_01485 2.5e-250 dnaB L Replication initiation and membrane attachment
LPKPLPPA_01486 2.7e-163 dnaI L Primosomal protein DnaI
LPKPLPPA_01487 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LPKPLPPA_01488 1.4e-72 K LytTr DNA-binding domain
LPKPLPPA_01489 1.9e-74 S Protein of unknown function (DUF3021)
LPKPLPPA_01490 4.8e-171 V ABC transporter
LPKPLPPA_01491 1.3e-131 S domain protein
LPKPLPPA_01492 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LPKPLPPA_01493 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LPKPLPPA_01494 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LPKPLPPA_01495 9.8e-191 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LPKPLPPA_01496 3.5e-91 yqeG S HAD phosphatase, family IIIA
LPKPLPPA_01497 4.7e-210 yqeH S Ribosome biogenesis GTPase YqeH
LPKPLPPA_01498 4.4e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LPKPLPPA_01499 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
LPKPLPPA_01500 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LPKPLPPA_01501 2.2e-218 ylbM S Belongs to the UPF0348 family
LPKPLPPA_01502 2.9e-96 yceD S Uncharacterized ACR, COG1399
LPKPLPPA_01503 1.1e-130 K response regulator
LPKPLPPA_01504 1.9e-281 arlS 2.7.13.3 T Histidine kinase
LPKPLPPA_01505 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LPKPLPPA_01506 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LPKPLPPA_01507 9.6e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LPKPLPPA_01508 7.3e-64 yodB K Transcriptional regulator, HxlR family
LPKPLPPA_01509 8.1e-204 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LPKPLPPA_01510 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LPKPLPPA_01511 2.9e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LPKPLPPA_01512 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LPKPLPPA_01513 0.0 S membrane
LPKPLPPA_01514 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
LPKPLPPA_01515 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LPKPLPPA_01516 5.6e-87 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LPKPLPPA_01517 4.5e-118 gluP 3.4.21.105 S Rhomboid family
LPKPLPPA_01518 6e-35 yqgQ S Bacterial protein of unknown function (DUF910)
LPKPLPPA_01519 1.5e-57 yqhL P Rhodanese-like protein
LPKPLPPA_01520 1.1e-18 S Protein of unknown function (DUF3042)
LPKPLPPA_01521 9.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LPKPLPPA_01522 1.1e-261 glnA 6.3.1.2 E glutamine synthetase
LPKPLPPA_01523 2.8e-205 EGP Major facilitator Superfamily
LPKPLPPA_01524 4.3e-152 S haloacid dehalogenase-like hydrolase
LPKPLPPA_01525 2.4e-07
LPKPLPPA_01526 8.1e-179 D Alpha beta
LPKPLPPA_01527 6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
LPKPLPPA_01528 3.9e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LPKPLPPA_01529 2.9e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
LPKPLPPA_01530 9.2e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LPKPLPPA_01531 7.8e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
LPKPLPPA_01532 2.4e-112 ygaC J Belongs to the UPF0374 family
LPKPLPPA_01533 4.9e-90
LPKPLPPA_01534 3e-78
LPKPLPPA_01535 4.7e-157 hlyX S Transporter associated domain
LPKPLPPA_01536 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LPKPLPPA_01537 4.3e-43 XK27_09445 S Domain of unknown function (DUF1827)
LPKPLPPA_01538 0.0 clpE O Belongs to the ClpA ClpB family
LPKPLPPA_01539 6.9e-26
LPKPLPPA_01540 1.4e-66 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)