ORF_ID e_value Gene_name EC_number CAZy COGs Description
ACDNIGDB_00001 1.4e-158 lysR5 K LysR substrate binding domain
ACDNIGDB_00002 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
ACDNIGDB_00003 3e-251 G Major Facilitator
ACDNIGDB_00004 1.6e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACDNIGDB_00005 9.4e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ACDNIGDB_00006 9.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACDNIGDB_00007 1.1e-278 yjeM E Amino Acid
ACDNIGDB_00008 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACDNIGDB_00009 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
ACDNIGDB_00010 9.3e-124 srtA 3.4.22.70 M sortase family
ACDNIGDB_00011 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ACDNIGDB_00012 4.5e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ACDNIGDB_00013 0.0 dnaK O Heat shock 70 kDa protein
ACDNIGDB_00014 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACDNIGDB_00015 2.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ACDNIGDB_00016 6.7e-121 S GyrI-like small molecule binding domain
ACDNIGDB_00017 1.6e-282 lsa S ABC transporter
ACDNIGDB_00018 7.6e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
ACDNIGDB_00019 1.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACDNIGDB_00020 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACDNIGDB_00021 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACDNIGDB_00022 6e-46 rplGA J ribosomal protein
ACDNIGDB_00023 2e-46 ylxR K Protein of unknown function (DUF448)
ACDNIGDB_00024 3.3e-217 nusA K Participates in both transcription termination and antitermination
ACDNIGDB_00025 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
ACDNIGDB_00026 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACDNIGDB_00027 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ACDNIGDB_00028 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
ACDNIGDB_00029 1.1e-136 cdsA 2.7.7.41 S Belongs to the CDS family
ACDNIGDB_00030 5.5e-135 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACDNIGDB_00031 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ACDNIGDB_00032 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ACDNIGDB_00033 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACDNIGDB_00034 2.8e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
ACDNIGDB_00035 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
ACDNIGDB_00036 9.8e-117 plsC 2.3.1.51 I Acyltransferase
ACDNIGDB_00037 8.6e-201 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
ACDNIGDB_00038 6.1e-300 mdlB V ABC transporter
ACDNIGDB_00039 0.0 mdlA V ABC transporter
ACDNIGDB_00040 1.5e-30 yneF S Uncharacterised protein family (UPF0154)
ACDNIGDB_00041 1.5e-34 ynzC S UPF0291 protein
ACDNIGDB_00042 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACDNIGDB_00043 1.1e-115 ung2 3.2.2.27 L Uracil-DNA glycosylase
ACDNIGDB_00044 6.5e-75 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
ACDNIGDB_00045 2.7e-117 lepB 3.4.21.89 U Belongs to the peptidase S26 family
ACDNIGDB_00046 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ACDNIGDB_00047 2.2e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ACDNIGDB_00048 7.4e-97 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACDNIGDB_00049 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ACDNIGDB_00050 3.2e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACDNIGDB_00051 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ACDNIGDB_00052 1.6e-287 pipD E Dipeptidase
ACDNIGDB_00053 7.8e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ACDNIGDB_00054 0.0 smc D Required for chromosome condensation and partitioning
ACDNIGDB_00055 1.6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ACDNIGDB_00056 0.0 oppA E ABC transporter substrate-binding protein
ACDNIGDB_00057 2.8e-298 oppA E ABC transporter substrate-binding protein
ACDNIGDB_00058 3.2e-30 oppA E ABC transporter substrate-binding protein
ACDNIGDB_00059 2.1e-163 oppC P Binding-protein-dependent transport system inner membrane component
ACDNIGDB_00060 7.5e-180 oppB P ABC transporter permease
ACDNIGDB_00061 4.4e-180 oppF P Belongs to the ABC transporter superfamily
ACDNIGDB_00062 1.1e-192 oppD P Belongs to the ABC transporter superfamily
ACDNIGDB_00063 2.6e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACDNIGDB_00064 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ACDNIGDB_00065 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACDNIGDB_00066 9.6e-308 yloV S DAK2 domain fusion protein YloV
ACDNIGDB_00067 1.4e-57 asp S Asp23 family, cell envelope-related function
ACDNIGDB_00068 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
ACDNIGDB_00069 1e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
ACDNIGDB_00070 3.1e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
ACDNIGDB_00071 1.4e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ACDNIGDB_00072 0.0 KLT serine threonine protein kinase
ACDNIGDB_00073 4.5e-140 stp 3.1.3.16 T phosphatase
ACDNIGDB_00074 1.2e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACDNIGDB_00075 7.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACDNIGDB_00076 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACDNIGDB_00077 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ACDNIGDB_00078 4.7e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
ACDNIGDB_00079 4.6e-48
ACDNIGDB_00080 1.7e-264 recN L May be involved in recombinational repair of damaged DNA
ACDNIGDB_00081 3.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
ACDNIGDB_00082 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ACDNIGDB_00083 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ACDNIGDB_00084 3.6e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ACDNIGDB_00085 8.1e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACDNIGDB_00086 8e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACDNIGDB_00087 2.2e-73 yqhY S Asp23 family, cell envelope-related function
ACDNIGDB_00088 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACDNIGDB_00089 2.8e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ACDNIGDB_00090 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
ACDNIGDB_00091 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
ACDNIGDB_00092 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
ACDNIGDB_00093 1.2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACDNIGDB_00094 6.3e-246 S Uncharacterized protein conserved in bacteria (DUF2325)
ACDNIGDB_00095 1.2e-12
ACDNIGDB_00096 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
ACDNIGDB_00097 1.2e-92 S ECF-type riboflavin transporter, S component
ACDNIGDB_00098 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
ACDNIGDB_00099 1.4e-59
ACDNIGDB_00100 5.2e-56 K Acetyltransferase (GNAT) domain
ACDNIGDB_00101 4.7e-305 S Predicted membrane protein (DUF2207)
ACDNIGDB_00102 1.2e-187 yhjX P Major Facilitator Superfamily
ACDNIGDB_00103 6.9e-83 I Carboxylesterase family
ACDNIGDB_00104 2.7e-63 I Carboxylesterase family
ACDNIGDB_00105 7e-161 rhaS6 K helix_turn_helix, arabinose operon control protein
ACDNIGDB_00106 2.1e-168 2.7.1.2 GK ROK family
ACDNIGDB_00107 4.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
ACDNIGDB_00108 8.6e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
ACDNIGDB_00109 0.0 oppA E ABC transporter substrate-binding protein
ACDNIGDB_00110 1.2e-76 K MerR HTH family regulatory protein
ACDNIGDB_00111 1.8e-265 lmrB EGP Major facilitator Superfamily
ACDNIGDB_00112 7.1e-98 S Domain of unknown function (DUF4811)
ACDNIGDB_00113 3.5e-128 pnb C nitroreductase
ACDNIGDB_00114 2.6e-224 I transferase activity, transferring acyl groups other than amino-acyl groups
ACDNIGDB_00115 2.1e-108 fic D Fic/DOC family
ACDNIGDB_00116 6.6e-72
ACDNIGDB_00117 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ACDNIGDB_00119 5.2e-122 S CAAX protease self-immunity
ACDNIGDB_00120 2.5e-141 S haloacid dehalogenase-like hydrolase
ACDNIGDB_00121 0.0 pepN 3.4.11.2 E aminopeptidase
ACDNIGDB_00122 4.2e-50
ACDNIGDB_00123 1e-19
ACDNIGDB_00124 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
ACDNIGDB_00125 1.6e-233 sptS 2.7.13.3 T Histidine kinase
ACDNIGDB_00126 5.3e-116 K response regulator
ACDNIGDB_00127 1.9e-112 2.7.6.5 T Region found in RelA / SpoT proteins
ACDNIGDB_00128 8.3e-21 ltrA S Bacterial low temperature requirement A protein (LtrA)
ACDNIGDB_00129 6.9e-66 O OsmC-like protein
ACDNIGDB_00130 1.6e-288 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ACDNIGDB_00131 4.4e-180 E ABC transporter, ATP-binding protein
ACDNIGDB_00134 0.0 infB UW LPXTG-motif cell wall anchor domain protein
ACDNIGDB_00135 0.0 3.1.31.1 M domain protein
ACDNIGDB_00136 1.6e-266 E amino acid
ACDNIGDB_00137 1.6e-171 K LysR substrate binding domain
ACDNIGDB_00138 0.0 1.3.5.4 C FAD binding domain
ACDNIGDB_00139 4.4e-242 brnQ U Component of the transport system for branched-chain amino acids
ACDNIGDB_00140 2.5e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ACDNIGDB_00141 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
ACDNIGDB_00142 3.2e-88 S Peptidase propeptide and YPEB domain
ACDNIGDB_00143 2.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
ACDNIGDB_00144 1.7e-249 yhjX_2 P Major Facilitator Superfamily
ACDNIGDB_00145 4.6e-236 yhjX_2 P Major Facilitator Superfamily
ACDNIGDB_00146 3.3e-163 arbZ I Phosphate acyltransferases
ACDNIGDB_00147 2.5e-183 arbY M Glycosyl transferase family 8
ACDNIGDB_00148 9.4e-183 arbY M Glycosyl transferase family 8
ACDNIGDB_00149 3.2e-155 arbx M Glycosyl transferase family 8
ACDNIGDB_00150 3.6e-148 arbV 2.3.1.51 I Acyl-transferase
ACDNIGDB_00153 1.2e-129 K response regulator
ACDNIGDB_00154 0.0 vicK 2.7.13.3 T Histidine kinase
ACDNIGDB_00155 3.5e-252 yycH S YycH protein
ACDNIGDB_00156 1.4e-142 yycI S YycH protein
ACDNIGDB_00157 3.3e-149 vicX 3.1.26.11 S domain protein
ACDNIGDB_00158 3.5e-182 htrA 3.4.21.107 O serine protease
ACDNIGDB_00159 9.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACDNIGDB_00160 2.1e-109 P Cobalt transport protein
ACDNIGDB_00161 4.3e-250 cbiO1 S ABC transporter, ATP-binding protein
ACDNIGDB_00162 4.8e-94 S ABC-type cobalt transport system, permease component
ACDNIGDB_00163 2.3e-170 K helix_turn_helix, arabinose operon control protein
ACDNIGDB_00164 2e-147 htpX O Belongs to the peptidase M48B family
ACDNIGDB_00165 9.9e-92 lemA S LemA family
ACDNIGDB_00166 8.3e-183 ybiR P Citrate transporter
ACDNIGDB_00167 1.3e-69 S Iron-sulphur cluster biosynthesis
ACDNIGDB_00168 1.7e-16
ACDNIGDB_00169 1.7e-154
ACDNIGDB_00171 4.3e-247 ydaM M Glycosyl transferase
ACDNIGDB_00172 7.1e-214 G Glycosyl hydrolases family 8
ACDNIGDB_00173 4.5e-120 yfbR S HD containing hydrolase-like enzyme
ACDNIGDB_00174 3.7e-162 L HNH nucleases
ACDNIGDB_00175 9.6e-138 glnQ E ABC transporter, ATP-binding protein
ACDNIGDB_00176 8.2e-280 glnP P ABC transporter permease
ACDNIGDB_00177 1.2e-106 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
ACDNIGDB_00178 1.5e-64 yeaO S Protein of unknown function, DUF488
ACDNIGDB_00179 1.6e-127 terC P Integral membrane protein TerC family
ACDNIGDB_00180 2.3e-93 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
ACDNIGDB_00181 2.2e-179 K Transcriptional regulator
ACDNIGDB_00182 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
ACDNIGDB_00183 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
ACDNIGDB_00184 7.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACDNIGDB_00185 7.2e-124 yoaK S Protein of unknown function (DUF1275)
ACDNIGDB_00186 1.8e-203 xerS L Belongs to the 'phage' integrase family
ACDNIGDB_00187 6.7e-167 K Transcriptional regulator
ACDNIGDB_00188 3.7e-151
ACDNIGDB_00189 3.8e-162 degV S EDD domain protein, DegV family
ACDNIGDB_00190 3.8e-64
ACDNIGDB_00191 0.0 FbpA K Fibronectin-binding protein
ACDNIGDB_00192 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
ACDNIGDB_00193 2.8e-196 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ACDNIGDB_00194 1.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ACDNIGDB_00195 2.3e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACDNIGDB_00196 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
ACDNIGDB_00197 9.9e-58
ACDNIGDB_00198 1e-47 degV S DegV family
ACDNIGDB_00199 1.2e-88 degV S DegV family
ACDNIGDB_00200 6.3e-240 cpdA S Calcineurin-like phosphoesterase
ACDNIGDB_00201 2.4e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
ACDNIGDB_00202 2e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ACDNIGDB_00203 4.2e-106 ypsA S Belongs to the UPF0398 family
ACDNIGDB_00204 1.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ACDNIGDB_00205 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
ACDNIGDB_00206 1.2e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACDNIGDB_00207 6.7e-116 dnaD L DnaD domain protein
ACDNIGDB_00208 2.9e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
ACDNIGDB_00209 4.8e-90 ypmB S Protein conserved in bacteria
ACDNIGDB_00210 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
ACDNIGDB_00211 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
ACDNIGDB_00212 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
ACDNIGDB_00213 4.4e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
ACDNIGDB_00214 4.3e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
ACDNIGDB_00215 4.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
ACDNIGDB_00216 5.2e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ACDNIGDB_00217 1.6e-272 V ABC-type multidrug transport system, ATPase and permease components
ACDNIGDB_00218 1.1e-289 V ABC-type multidrug transport system, ATPase and permease components
ACDNIGDB_00219 1.6e-159 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
ACDNIGDB_00220 6.1e-160 rbsU U ribose uptake protein RbsU
ACDNIGDB_00221 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ACDNIGDB_00222 3.1e-83 6.3.3.2 S ASCH
ACDNIGDB_00223 3.7e-137 2.4.2.3 F Phosphorylase superfamily
ACDNIGDB_00224 1.5e-88 2.3.1.57 K Acetyltransferase (GNAT) family
ACDNIGDB_00225 1.4e-98 rimL J Acetyltransferase (GNAT) domain
ACDNIGDB_00226 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ACDNIGDB_00227 0.0 typA T GTP-binding protein TypA
ACDNIGDB_00228 5.6e-209 ftsW D Belongs to the SEDS family
ACDNIGDB_00229 6.1e-52 ylbG S UPF0298 protein
ACDNIGDB_00230 1.6e-94 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
ACDNIGDB_00231 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACDNIGDB_00232 2.5e-186 ylbL T Belongs to the peptidase S16 family
ACDNIGDB_00233 2.4e-79 comEA L Competence protein ComEA
ACDNIGDB_00234 0.0 comEC S Competence protein ComEC
ACDNIGDB_00235 1.2e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
ACDNIGDB_00236 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
ACDNIGDB_00237 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACDNIGDB_00238 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACDNIGDB_00239 7.7e-160
ACDNIGDB_00240 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACDNIGDB_00241 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ACDNIGDB_00242 3.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACDNIGDB_00243 2e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
ACDNIGDB_00244 6.7e-89 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACDNIGDB_00245 1.5e-81
ACDNIGDB_00246 1.2e-70 S Domain of unknown function (DUF4767)
ACDNIGDB_00247 7.7e-225
ACDNIGDB_00248 3.7e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ACDNIGDB_00250 4.5e-76 S HIRAN
ACDNIGDB_00252 7.2e-164 htpX O Peptidase family M48
ACDNIGDB_00253 7e-32
ACDNIGDB_00254 4e-223 patA 2.6.1.1 E Aminotransferase
ACDNIGDB_00255 6.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ACDNIGDB_00256 4.8e-125 E GDSL-like Lipase/Acylhydrolase family
ACDNIGDB_00257 1.5e-08 E GDSL-like Lipase/Acylhydrolase family
ACDNIGDB_00258 1.4e-106 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACDNIGDB_00259 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACDNIGDB_00260 1e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
ACDNIGDB_00261 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
ACDNIGDB_00262 2e-47 yqeY S YqeY-like protein
ACDNIGDB_00263 4.7e-174 phoH T phosphate starvation-inducible protein PhoH
ACDNIGDB_00264 1.2e-91 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACDNIGDB_00265 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACDNIGDB_00266 1.6e-137 recO L Involved in DNA repair and RecF pathway recombination
ACDNIGDB_00267 3.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
ACDNIGDB_00268 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
ACDNIGDB_00269 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ACDNIGDB_00270 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ACDNIGDB_00271 2.5e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
ACDNIGDB_00272 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACDNIGDB_00273 1.2e-246 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
ACDNIGDB_00274 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
ACDNIGDB_00275 3.3e-124 skfE V ATPases associated with a variety of cellular activities
ACDNIGDB_00276 2.1e-138
ACDNIGDB_00277 2.3e-108
ACDNIGDB_00278 8.1e-22
ACDNIGDB_00279 1e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
ACDNIGDB_00280 4e-133
ACDNIGDB_00281 2.5e-167
ACDNIGDB_00282 2e-229 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
ACDNIGDB_00283 3.5e-52 ybjQ S Belongs to the UPF0145 family
ACDNIGDB_00284 8.3e-161 XK27_05540 S DUF218 domain
ACDNIGDB_00285 1.4e-87 yxeH S hydrolase
ACDNIGDB_00286 2.5e-52 yxeH S hydrolase
ACDNIGDB_00287 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ACDNIGDB_00288 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ACDNIGDB_00289 8.9e-116 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ACDNIGDB_00290 2.6e-109 lacA 2.3.1.79 S Transferase hexapeptide repeat
ACDNIGDB_00291 1.8e-124 magIII L Base excision DNA repair protein, HhH-GPD family
ACDNIGDB_00292 3.3e-166 akr5f 1.1.1.346 S reductase
ACDNIGDB_00293 1.9e-54 C Aldo/keto reductase family
ACDNIGDB_00294 2.9e-14 C Aldo/keto reductase family
ACDNIGDB_00295 9e-122 ybhL S Belongs to the BI1 family
ACDNIGDB_00296 2.3e-105 4.1.1.45 S Amidohydrolase
ACDNIGDB_00297 1.5e-33 4.1.1.45 S Amidohydrolase
ACDNIGDB_00298 5.7e-244 yrvN L AAA C-terminal domain
ACDNIGDB_00299 7.3e-58 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
ACDNIGDB_00300 1.3e-53 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
ACDNIGDB_00301 2.5e-86 XK27_09675 K Acetyltransferase (GNAT) domain
ACDNIGDB_00302 7.9e-69 ogt 2.1.1.63 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
ACDNIGDB_00303 6.2e-76 K Transcriptional regulator
ACDNIGDB_00304 5.2e-08 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
ACDNIGDB_00305 6.9e-80 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
ACDNIGDB_00306 4e-95 K Acetyltransferase (GNAT) family
ACDNIGDB_00307 1.5e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
ACDNIGDB_00308 3.1e-93 dps P Belongs to the Dps family
ACDNIGDB_00309 4.6e-35 copZ C Heavy-metal-associated domain
ACDNIGDB_00310 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
ACDNIGDB_00311 5.5e-50 K LytTr DNA-binding domain
ACDNIGDB_00312 1.3e-21 cylB V ABC-2 type transporter
ACDNIGDB_00313 2.4e-68 S pyridoxamine 5-phosphate
ACDNIGDB_00314 3.1e-77 yobV1 K WYL domain
ACDNIGDB_00315 1.3e-70 yobV1 K WYL domain
ACDNIGDB_00316 4.1e-30 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
ACDNIGDB_00317 2.3e-63 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
ACDNIGDB_00318 4.1e-264 npr 1.11.1.1 C NADH oxidase
ACDNIGDB_00319 1.9e-32 G Major facilitator Superfamily
ACDNIGDB_00320 4.9e-61 S Sulfite exporter TauE/SafE
ACDNIGDB_00321 1.2e-89 mdt(A) EGP Major facilitator Superfamily
ACDNIGDB_00322 7.2e-88 mdt(A) EGP Major facilitator Superfamily
ACDNIGDB_00323 2.1e-117 GM NAD(P)H-binding
ACDNIGDB_00324 1.7e-231 E Alpha/beta hydrolase of unknown function (DUF1100)
ACDNIGDB_00325 9.2e-101 K Transcriptional regulator C-terminal region
ACDNIGDB_00327 4.9e-156 C Aldo keto reductase
ACDNIGDB_00328 3.9e-126 lmrA 3.6.3.44 V ABC transporter
ACDNIGDB_00329 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
ACDNIGDB_00330 1.7e-32 mta K helix_turn_helix, mercury resistance
ACDNIGDB_00331 4.4e-35 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
ACDNIGDB_00332 1.4e-189 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ACDNIGDB_00333 1.2e-41 yphH S Cupin domain
ACDNIGDB_00334 8.6e-290 V ABC-type multidrug transport system, ATPase and permease components
ACDNIGDB_00335 3.2e-292 P ABC transporter
ACDNIGDB_00336 1.9e-75 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
ACDNIGDB_00337 2.5e-11 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
ACDNIGDB_00338 5.1e-231 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
ACDNIGDB_00339 2.7e-48
ACDNIGDB_00340 5.2e-68 K HxlR family
ACDNIGDB_00341 4.5e-17 L Plasmid pRiA4b ORF-3-like protein
ACDNIGDB_00342 2.7e-32 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ACDNIGDB_00343 1.4e-11 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ACDNIGDB_00344 4.6e-247 brnQ U Component of the transport system for branched-chain amino acids
ACDNIGDB_00345 5.8e-63 S Putative adhesin
ACDNIGDB_00346 3.9e-113 3.6.1.55 F NUDIX domain
ACDNIGDB_00347 1.8e-110 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
ACDNIGDB_00348 1.1e-36 comGC U Required for transformation and DNA binding
ACDNIGDB_00349 4.7e-177 comGB NU type II secretion system
ACDNIGDB_00350 5.8e-180 comGA NU Type II IV secretion system protein
ACDNIGDB_00351 1.5e-132 yebC K Transcriptional regulatory protein
ACDNIGDB_00352 7.3e-97 S VanZ like family
ACDNIGDB_00353 4.3e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACDNIGDB_00354 4.5e-163 znuA P Belongs to the bacterial solute-binding protein 9 family
ACDNIGDB_00355 8.5e-150 yisY 1.11.1.10 S Alpha/beta hydrolase family
ACDNIGDB_00356 4.8e-115
ACDNIGDB_00357 8e-179 S Putative adhesin
ACDNIGDB_00358 5.3e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACDNIGDB_00359 8.6e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACDNIGDB_00360 4.4e-149 S Sucrose-6F-phosphate phosphohydrolase
ACDNIGDB_00361 2.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACDNIGDB_00362 8.1e-174 ybbR S YbbR-like protein
ACDNIGDB_00363 3.4e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ACDNIGDB_00364 1.3e-209 potD P ABC transporter
ACDNIGDB_00365 8.5e-137 potC P ABC transporter permease
ACDNIGDB_00366 2.7e-130 potB P ABC transporter permease
ACDNIGDB_00367 5.9e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
ACDNIGDB_00368 4.4e-166 murB 1.3.1.98 M Cell wall formation
ACDNIGDB_00369 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
ACDNIGDB_00370 1.3e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
ACDNIGDB_00371 2.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
ACDNIGDB_00372 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACDNIGDB_00373 8e-157 ycsE S Sucrose-6F-phosphate phosphohydrolase
ACDNIGDB_00374 2.9e-93
ACDNIGDB_00375 6.6e-91
ACDNIGDB_00377 1e-107 3.2.2.20 K acetyltransferase
ACDNIGDB_00378 2.3e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ACDNIGDB_00379 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ACDNIGDB_00380 2.5e-28 secG U Preprotein translocase
ACDNIGDB_00381 1.2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ACDNIGDB_00382 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ACDNIGDB_00383 1.3e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
ACDNIGDB_00384 1.6e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ACDNIGDB_00385 2.3e-187 cggR K Putative sugar-binding domain
ACDNIGDB_00387 1.2e-277 ycaM E amino acid
ACDNIGDB_00388 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ACDNIGDB_00389 6.2e-171 whiA K May be required for sporulation
ACDNIGDB_00390 4.9e-193 ybhK S Required for morphogenesis under gluconeogenic growth conditions
ACDNIGDB_00391 6e-160 rapZ S Displays ATPase and GTPase activities
ACDNIGDB_00392 1.1e-90 S Short repeat of unknown function (DUF308)
ACDNIGDB_00393 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ACDNIGDB_00394 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ACDNIGDB_00395 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
ACDNIGDB_00396 1.6e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
ACDNIGDB_00397 5.2e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ACDNIGDB_00398 1.4e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACDNIGDB_00399 9.2e-181 lacR K Transcriptional regulator
ACDNIGDB_00400 5.4e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACDNIGDB_00401 1.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ACDNIGDB_00402 6.8e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ACDNIGDB_00403 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACDNIGDB_00404 4.1e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ACDNIGDB_00405 3.1e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ACDNIGDB_00406 1.2e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ACDNIGDB_00407 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ACDNIGDB_00408 1.9e-65 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACDNIGDB_00409 3.6e-27 pncA Q Isochorismatase family
ACDNIGDB_00410 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ACDNIGDB_00411 5.7e-126 alkD L DNA alkylation repair enzyme
ACDNIGDB_00412 2.9e-128 XK27_06785 V ABC transporter, ATP-binding protein
ACDNIGDB_00413 0.0 XK27_06780 V ABC transporter permease
ACDNIGDB_00414 0.0 pepO 3.4.24.71 O Peptidase family M13
ACDNIGDB_00415 4.8e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
ACDNIGDB_00416 5.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACDNIGDB_00417 3.3e-283 thrC 4.2.3.1 E Threonine synthase
ACDNIGDB_00418 5.3e-231 hom1 1.1.1.3 E homoserine dehydrogenase
ACDNIGDB_00419 3.3e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ACDNIGDB_00420 4.2e-161 lysR7 K LysR substrate binding domain
ACDNIGDB_00421 0.0 1.3.5.4 C FMN_bind
ACDNIGDB_00422 8.4e-119 drgA C nitroreductase
ACDNIGDB_00423 2.8e-28
ACDNIGDB_00424 8.4e-50
ACDNIGDB_00425 2e-42 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
ACDNIGDB_00426 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
ACDNIGDB_00427 2.2e-139
ACDNIGDB_00428 2e-105 speG J Acetyltransferase (GNAT) domain
ACDNIGDB_00429 1e-09 K sequence-specific DNA binding
ACDNIGDB_00430 1.3e-54 K sequence-specific DNA binding
ACDNIGDB_00431 1.2e-141 S Protein of unknown function (DUF975)
ACDNIGDB_00432 1e-127 qmcA O prohibitin homologues
ACDNIGDB_00433 2e-149 ropB K Helix-turn-helix domain
ACDNIGDB_00434 2e-294 V ABC-type multidrug transport system, ATPase and permease components
ACDNIGDB_00435 1.7e-84 C nitroreductase
ACDNIGDB_00436 5e-282 V ABC transporter transmembrane region
ACDNIGDB_00437 1.1e-48
ACDNIGDB_00438 4.5e-36 K Acetyltransferase (GNAT) domain
ACDNIGDB_00439 1.2e-22 K Acetyltransferase (GNAT) domain
ACDNIGDB_00440 1.9e-152 S Protein of unknown function (DUF2785)
ACDNIGDB_00441 1.6e-48 S MazG-like family
ACDNIGDB_00442 2.1e-63
ACDNIGDB_00443 1.4e-135
ACDNIGDB_00445 2.8e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACDNIGDB_00447 3.7e-262 pepC 3.4.22.40 E aminopeptidase
ACDNIGDB_00448 7.5e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
ACDNIGDB_00449 8.4e-173 pepC 3.4.22.40 E aminopeptidase
ACDNIGDB_00450 8.1e-76 pepC 3.4.22.40 E aminopeptidase
ACDNIGDB_00451 7.7e-43
ACDNIGDB_00452 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ACDNIGDB_00453 2.1e-76 hsp O Belongs to the small heat shock protein (HSP20) family
ACDNIGDB_00454 7.6e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ACDNIGDB_00455 3.7e-82
ACDNIGDB_00456 1.4e-248 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ACDNIGDB_00457 4e-41 yydK K UTRA
ACDNIGDB_00458 1.2e-42 yydK K UTRA
ACDNIGDB_00459 1.4e-166 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ACDNIGDB_00460 4.7e-116 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ACDNIGDB_00461 3.4e-132 gmuR K UTRA
ACDNIGDB_00462 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
ACDNIGDB_00463 1.3e-38
ACDNIGDB_00464 3.4e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
ACDNIGDB_00465 2.9e-268 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ACDNIGDB_00466 4.4e-282 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ACDNIGDB_00467 5.2e-156 ypbG 2.7.1.2 GK ROK family
ACDNIGDB_00468 1.1e-113
ACDNIGDB_00470 8.6e-113 E Belongs to the SOS response-associated peptidase family
ACDNIGDB_00471 5.7e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
ACDNIGDB_00472 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
ACDNIGDB_00473 5.2e-99 S TPM domain
ACDNIGDB_00474 3e-91 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
ACDNIGDB_00475 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACDNIGDB_00476 2e-146 tatD L hydrolase, TatD family
ACDNIGDB_00477 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ACDNIGDB_00478 1.2e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ACDNIGDB_00479 7.4e-36 veg S Biofilm formation stimulator VEG
ACDNIGDB_00480 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
ACDNIGDB_00481 6.9e-219 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACDNIGDB_00482 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACDNIGDB_00483 2.2e-176 yvdE K helix_turn _helix lactose operon repressor
ACDNIGDB_00484 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
ACDNIGDB_00485 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
ACDNIGDB_00486 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
ACDNIGDB_00487 2.4e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
ACDNIGDB_00488 3.6e-210 msmX P Belongs to the ABC transporter superfamily
ACDNIGDB_00489 5e-229 malE G Bacterial extracellular solute-binding protein
ACDNIGDB_00490 6.5e-254 malF P Binding-protein-dependent transport system inner membrane component
ACDNIGDB_00491 9.7e-155 malG P ABC transporter permease
ACDNIGDB_00492 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
ACDNIGDB_00493 3.3e-266 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
ACDNIGDB_00494 6e-73 S Domain of unknown function (DUF1934)
ACDNIGDB_00495 2.9e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ACDNIGDB_00496 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ACDNIGDB_00497 2.2e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACDNIGDB_00498 6e-236 pbuX F xanthine permease
ACDNIGDB_00499 5.3e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ACDNIGDB_00500 6.6e-134 K DNA-binding helix-turn-helix protein
ACDNIGDB_00501 1.6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ACDNIGDB_00503 1.2e-132 K Helix-turn-helix
ACDNIGDB_00504 4.1e-37
ACDNIGDB_00505 2.4e-66 doc S Fic/DOC family
ACDNIGDB_00506 6.5e-93 K Bacterial regulatory proteins, tetR family
ACDNIGDB_00507 1.8e-112 1.6.5.2 S Flavodoxin-like fold
ACDNIGDB_00508 5.7e-44 yjdF S Protein of unknown function (DUF2992)
ACDNIGDB_00510 7.9e-51
ACDNIGDB_00511 2.1e-50 S Domain of unknown function (DUF4160)
ACDNIGDB_00512 3.1e-58 yjdF S Protein of unknown function (DUF2992)
ACDNIGDB_00513 3.9e-98 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACDNIGDB_00514 1.3e-93
ACDNIGDB_00515 1.8e-272 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
ACDNIGDB_00516 2.3e-278 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
ACDNIGDB_00517 2.6e-43 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
ACDNIGDB_00518 8.6e-186 yfdV S Membrane transport protein
ACDNIGDB_00519 7.1e-40
ACDNIGDB_00520 2.4e-22 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ACDNIGDB_00521 3.6e-78 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ACDNIGDB_00522 5e-79 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ACDNIGDB_00523 4.9e-67 S Putative adhesin
ACDNIGDB_00524 6e-79
ACDNIGDB_00525 9.3e-08
ACDNIGDB_00526 6.3e-63 pipD E Dipeptidase
ACDNIGDB_00527 6.3e-122 pipD E Dipeptidase
ACDNIGDB_00528 2e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACDNIGDB_00529 0.0 rafA 3.2.1.22 G alpha-galactosidase
ACDNIGDB_00530 1e-187 ABC-SBP S ABC transporter
ACDNIGDB_00531 4.9e-141 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
ACDNIGDB_00532 3.4e-135 XK27_08845 S ABC transporter, ATP-binding protein
ACDNIGDB_00533 3.2e-284 ybeC E amino acid
ACDNIGDB_00534 8e-41 rpmE2 J Ribosomal protein L31
ACDNIGDB_00535 2.9e-262 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ACDNIGDB_00536 7.7e-261 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ACDNIGDB_00537 5.9e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ACDNIGDB_00538 1.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACDNIGDB_00539 2.4e-124 S (CBS) domain
ACDNIGDB_00540 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ACDNIGDB_00541 3.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ACDNIGDB_00542 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACDNIGDB_00543 1.8e-34 yabO J S4 domain protein
ACDNIGDB_00544 2.3e-60 divIC D Septum formation initiator
ACDNIGDB_00545 9.9e-61 yabR J S1 RNA binding domain
ACDNIGDB_00546 2.4e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ACDNIGDB_00547 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACDNIGDB_00548 0.0 S membrane
ACDNIGDB_00549 4.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACDNIGDB_00550 8.9e-192 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACDNIGDB_00551 2.7e-296 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
ACDNIGDB_00552 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
ACDNIGDB_00553 1.3e-209 3.1.21.3 V Type I restriction modification DNA specificity domain
ACDNIGDB_00554 2.4e-178 L Belongs to the 'phage' integrase family
ACDNIGDB_00555 1.6e-224 3.1.21.3 V Type I restriction modification DNA specificity domain
ACDNIGDB_00556 1.8e-292 hsdM 2.1.1.72 V type I restriction-modification system
ACDNIGDB_00557 2.6e-134
ACDNIGDB_00558 0.0 KL domain protein
ACDNIGDB_00559 1.1e-231 S Tetratricopeptide repeat protein
ACDNIGDB_00560 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ACDNIGDB_00561 9.4e-242 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
ACDNIGDB_00562 2.3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
ACDNIGDB_00563 2e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
ACDNIGDB_00564 4.4e-98 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ACDNIGDB_00565 1.9e-58 M Lysin motif
ACDNIGDB_00566 1.8e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ACDNIGDB_00567 2.9e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACDNIGDB_00568 1.1e-135 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACDNIGDB_00569 3.2e-62 ribT K acetyltransferase
ACDNIGDB_00570 2.5e-169 xerD D recombinase XerD
ACDNIGDB_00571 1.5e-166 cvfB S S1 domain
ACDNIGDB_00572 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
ACDNIGDB_00573 2.7e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
ACDNIGDB_00575 0.0 dnaE 2.7.7.7 L DNA polymerase
ACDNIGDB_00576 2.1e-28 S Protein of unknown function (DUF2929)
ACDNIGDB_00577 8.1e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
ACDNIGDB_00578 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ACDNIGDB_00579 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
ACDNIGDB_00580 9.3e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ACDNIGDB_00581 1.4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ACDNIGDB_00582 0.0 oatA I Acyltransferase
ACDNIGDB_00583 3.9e-240 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACDNIGDB_00584 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ACDNIGDB_00585 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
ACDNIGDB_00586 2.8e-87 dedA 3.1.3.1 S SNARE associated Golgi protein
ACDNIGDB_00587 1.5e-115 GM NmrA-like family
ACDNIGDB_00588 7.7e-247 yagE E amino acid
ACDNIGDB_00589 3.1e-77 S Rib/alpha-like repeat
ACDNIGDB_00590 4.6e-64 S Domain of unknown function DUF1828
ACDNIGDB_00591 7.2e-68
ACDNIGDB_00592 1.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ACDNIGDB_00593 7.8e-216 iscS2 2.8.1.7 E Aminotransferase class V
ACDNIGDB_00594 5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACDNIGDB_00595 2.9e-125 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ACDNIGDB_00596 4.2e-211 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
ACDNIGDB_00597 5.8e-55 3.6.3.8 P P-type ATPase
ACDNIGDB_00598 0.0 3.6.3.8 P P-type ATPase
ACDNIGDB_00599 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ACDNIGDB_00600 2.8e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ACDNIGDB_00601 9.2e-124 S Haloacid dehalogenase-like hydrolase
ACDNIGDB_00602 3.6e-111 radC L DNA repair protein
ACDNIGDB_00603 6.4e-166 mreB D cell shape determining protein MreB
ACDNIGDB_00604 1e-143 mreC M Involved in formation and maintenance of cell shape
ACDNIGDB_00605 5.4e-95 mreD
ACDNIGDB_00606 3.6e-13 S Protein of unknown function (DUF4044)
ACDNIGDB_00607 3.9e-51 S Protein of unknown function (DUF3397)
ACDNIGDB_00608 4.1e-77 mraZ K Belongs to the MraZ family
ACDNIGDB_00609 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ACDNIGDB_00610 6.3e-55 ftsL D Cell division protein FtsL
ACDNIGDB_00611 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
ACDNIGDB_00612 1.6e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACDNIGDB_00613 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACDNIGDB_00614 1.2e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACDNIGDB_00615 6.3e-154 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ACDNIGDB_00616 4.1e-240 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ACDNIGDB_00617 3.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACDNIGDB_00618 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ACDNIGDB_00619 2e-27 yggT S YGGT family
ACDNIGDB_00620 4.8e-148 ylmH S S4 domain protein
ACDNIGDB_00621 2.1e-119 gpsB D DivIVA domain protein
ACDNIGDB_00622 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACDNIGDB_00623 2e-32 cspA K 'Cold-shock' DNA-binding domain
ACDNIGDB_00624 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
ACDNIGDB_00626 1.6e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACDNIGDB_00627 3.3e-214 iscS 2.8.1.7 E Aminotransferase class V
ACDNIGDB_00628 1.6e-57 XK27_04120 S Putative amino acid metabolism
ACDNIGDB_00629 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ACDNIGDB_00630 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
ACDNIGDB_00631 5.1e-116 S Repeat protein
ACDNIGDB_00632 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ACDNIGDB_00633 9.9e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
ACDNIGDB_00634 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACDNIGDB_00635 3e-34 ykzG S Belongs to the UPF0356 family
ACDNIGDB_00636 4.6e-134 cobB K SIR2 family
ACDNIGDB_00637 6.7e-81
ACDNIGDB_00638 6.4e-273 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACDNIGDB_00639 1.8e-122 yugP S Putative neutral zinc metallopeptidase
ACDNIGDB_00640 6.3e-176 S Alpha/beta hydrolase of unknown function (DUF915)
ACDNIGDB_00641 6.2e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACDNIGDB_00642 2.4e-162 ypuA S Protein of unknown function (DUF1002)
ACDNIGDB_00643 2.2e-143 2.4.1.293 GT2 M Glycosyltransferase like family 2
ACDNIGDB_00644 6.9e-124 S Alpha/beta hydrolase family
ACDNIGDB_00645 1.4e-62
ACDNIGDB_00646 4.1e-181 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACDNIGDB_00647 2.4e-220 S CAAX protease self-immunity
ACDNIGDB_00648 2.8e-241 cycA E Amino acid permease
ACDNIGDB_00649 6.4e-114 luxT K Bacterial regulatory proteins, tetR family
ACDNIGDB_00650 1.1e-139
ACDNIGDB_00651 7.2e-286 S Cysteine-rich secretory protein family
ACDNIGDB_00652 2.8e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ACDNIGDB_00653 3.3e-95
ACDNIGDB_00654 6.5e-117 yjcE P Sodium proton antiporter
ACDNIGDB_00655 1.3e-141 yjcE P Sodium proton antiporter
ACDNIGDB_00656 1.4e-187 yibE S overlaps another CDS with the same product name
ACDNIGDB_00657 4.9e-118 yibF S overlaps another CDS with the same product name
ACDNIGDB_00658 7.6e-157 I alpha/beta hydrolase fold
ACDNIGDB_00659 0.0 G Belongs to the glycosyl hydrolase 31 family
ACDNIGDB_00660 5.3e-130 XK27_08435 K UTRA
ACDNIGDB_00661 2.4e-217 agaS G SIS domain
ACDNIGDB_00662 1.8e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACDNIGDB_00663 3.3e-83 2.7.1.191 G PTS system sorbose subfamily IIB component
ACDNIGDB_00664 2.9e-141 XK27_08455 G PTS system sorbose-specific iic component
ACDNIGDB_00665 5.5e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
ACDNIGDB_00666 9.3e-68 2.7.1.191 G PTS system fructose IIA component
ACDNIGDB_00667 1.3e-18 S PD-(D/E)XK nuclease family transposase
ACDNIGDB_00668 1e-76 M Protein of unknown function (DUF3737)
ACDNIGDB_00669 1.8e-80 patB 4.4.1.8 E Aminotransferase, class I
ACDNIGDB_00670 2.9e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
ACDNIGDB_00671 9.2e-68 S SdpI/YhfL protein family
ACDNIGDB_00672 9e-130 K Transcriptional regulatory protein, C terminal
ACDNIGDB_00673 5.3e-270 T PhoQ Sensor
ACDNIGDB_00674 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ACDNIGDB_00675 1.4e-107 vanZ V VanZ like family
ACDNIGDB_00676 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
ACDNIGDB_00677 6.8e-206 EGP Major facilitator Superfamily
ACDNIGDB_00678 1.4e-72
ACDNIGDB_00681 7.2e-197 ampC V Beta-lactamase
ACDNIGDB_00682 4.9e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
ACDNIGDB_00683 5.5e-112 tdk 2.7.1.21 F thymidine kinase
ACDNIGDB_00684 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACDNIGDB_00685 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ACDNIGDB_00686 1.2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ACDNIGDB_00687 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACDNIGDB_00688 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
ACDNIGDB_00689 2.1e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACDNIGDB_00690 5.9e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACDNIGDB_00691 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACDNIGDB_00692 5.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACDNIGDB_00693 2.7e-169 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACDNIGDB_00694 4.3e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACDNIGDB_00695 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ACDNIGDB_00696 2e-30 ywzB S Protein of unknown function (DUF1146)
ACDNIGDB_00697 2.2e-179 mbl D Cell shape determining protein MreB Mrl
ACDNIGDB_00698 2.5e-15 S DNA-directed RNA polymerase subunit beta
ACDNIGDB_00699 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
ACDNIGDB_00700 1.3e-34 S Protein of unknown function (DUF2969)
ACDNIGDB_00701 1.5e-222 rodA D Belongs to the SEDS family
ACDNIGDB_00702 5.2e-81 usp6 T universal stress protein
ACDNIGDB_00704 7.4e-239 rarA L recombination factor protein RarA
ACDNIGDB_00705 1e-81 yueI S Protein of unknown function (DUF1694)
ACDNIGDB_00706 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACDNIGDB_00708 4.6e-35
ACDNIGDB_00709 1.5e-82 mutT 3.6.1.55 F NUDIX domain
ACDNIGDB_00710 3.1e-73
ACDNIGDB_00711 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
ACDNIGDB_00712 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
ACDNIGDB_00713 7.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ACDNIGDB_00714 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACDNIGDB_00715 1.4e-65
ACDNIGDB_00716 4.6e-174 prmA J Ribosomal protein L11 methyltransferase
ACDNIGDB_00717 3e-87 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACDNIGDB_00718 0.0 S Bacterial membrane protein, YfhO
ACDNIGDB_00719 0.0 aha1 P E1-E2 ATPase
ACDNIGDB_00720 2.5e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
ACDNIGDB_00721 2.9e-257 yjjP S Putative threonine/serine exporter
ACDNIGDB_00722 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ACDNIGDB_00723 2.1e-260 frdC 1.3.5.4 C FAD binding domain
ACDNIGDB_00724 3.8e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ACDNIGDB_00725 2.8e-67 metI P ABC transporter permease
ACDNIGDB_00726 8.2e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACDNIGDB_00727 1.8e-156 metQ1 P Belongs to the nlpA lipoprotein family
ACDNIGDB_00728 7.6e-60 L nuclease
ACDNIGDB_00729 2.8e-146 F DNA/RNA non-specific endonuclease
ACDNIGDB_00730 2.7e-41 K Helix-turn-helix domain
ACDNIGDB_00731 1.1e-310 ybiT S ABC transporter, ATP-binding protein
ACDNIGDB_00732 3.7e-18 S Sugar efflux transporter for intercellular exchange
ACDNIGDB_00733 8.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ACDNIGDB_00734 2.2e-102 3.6.1.27 I Acid phosphatase homologues
ACDNIGDB_00736 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACDNIGDB_00737 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ACDNIGDB_00738 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACDNIGDB_00739 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
ACDNIGDB_00740 2.2e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACDNIGDB_00741 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
ACDNIGDB_00742 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ACDNIGDB_00743 5.6e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACDNIGDB_00744 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACDNIGDB_00745 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACDNIGDB_00746 3.6e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACDNIGDB_00747 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACDNIGDB_00748 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
ACDNIGDB_00749 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACDNIGDB_00750 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACDNIGDB_00751 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACDNIGDB_00752 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACDNIGDB_00753 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACDNIGDB_00754 2.7e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACDNIGDB_00755 5e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACDNIGDB_00756 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACDNIGDB_00757 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACDNIGDB_00758 1.4e-23 rpmD J Ribosomal protein L30
ACDNIGDB_00759 1.3e-70 rplO J Binds to the 23S rRNA
ACDNIGDB_00760 1.3e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ACDNIGDB_00761 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ACDNIGDB_00762 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACDNIGDB_00763 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
ACDNIGDB_00764 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACDNIGDB_00765 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACDNIGDB_00766 1.3e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACDNIGDB_00767 1.3e-61 rplQ J Ribosomal protein L17
ACDNIGDB_00768 5.1e-156 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACDNIGDB_00769 2.2e-162 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACDNIGDB_00770 1.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACDNIGDB_00771 4.2e-152 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ACDNIGDB_00772 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACDNIGDB_00773 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
ACDNIGDB_00774 1.2e-79
ACDNIGDB_00775 1.2e-160 1.6.5.2 GM NmrA-like family
ACDNIGDB_00776 3.8e-110 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
ACDNIGDB_00777 1.3e-128 pgm3 G Belongs to the phosphoglycerate mutase family
ACDNIGDB_00778 2.6e-52 K Transcriptional regulator, ArsR family
ACDNIGDB_00779 3.4e-155 czcD P cation diffusion facilitator family transporter
ACDNIGDB_00780 2e-42
ACDNIGDB_00781 5.4e-26
ACDNIGDB_00782 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACDNIGDB_00783 2.9e-148 dkg S reductase
ACDNIGDB_00784 2.2e-122 endA F DNA RNA non-specific endonuclease
ACDNIGDB_00785 4.3e-280 pipD E Dipeptidase
ACDNIGDB_00786 7.1e-203 malK P ATPases associated with a variety of cellular activities
ACDNIGDB_00787 9.5e-158 gtsB P ABC-type sugar transport systems, permease components
ACDNIGDB_00788 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
ACDNIGDB_00789 7.9e-257 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
ACDNIGDB_00790 3e-240 G Bacterial extracellular solute-binding protein
ACDNIGDB_00791 8.7e-52 ypaA S Protein of unknown function (DUF1304)
ACDNIGDB_00792 1.1e-77 yybA 2.3.1.57 K Transcriptional regulator
ACDNIGDB_00793 6.6e-96 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
ACDNIGDB_00794 1.4e-80 yjcF S Acetyltransferase (GNAT) domain
ACDNIGDB_00795 5.4e-167 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
ACDNIGDB_00796 1.4e-167 3.5.2.6 V Beta-lactamase enzyme family
ACDNIGDB_00797 3e-90 yobS K Bacterial regulatory proteins, tetR family
ACDNIGDB_00798 0.0 ydgH S MMPL family
ACDNIGDB_00799 3.4e-133 cof S haloacid dehalogenase-like hydrolase
ACDNIGDB_00800 2.1e-123 S SNARE associated Golgi protein
ACDNIGDB_00801 6e-180
ACDNIGDB_00802 7.2e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
ACDNIGDB_00803 5.8e-144 hipB K Helix-turn-helix
ACDNIGDB_00804 3.5e-151 I alpha/beta hydrolase fold
ACDNIGDB_00805 1.5e-106 yjbF S SNARE associated Golgi protein
ACDNIGDB_00806 1.1e-101 J Acetyltransferase (GNAT) domain
ACDNIGDB_00807 1.4e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACDNIGDB_00808 1.6e-185 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
ACDNIGDB_00809 0.0 L AAA domain
ACDNIGDB_00810 1.6e-230 yhaO L Ser Thr phosphatase family protein
ACDNIGDB_00811 3.3e-56 yheA S Belongs to the UPF0342 family
ACDNIGDB_00812 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ACDNIGDB_00813 3.6e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ACDNIGDB_00815 1.3e-259 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
ACDNIGDB_00816 1.3e-66
ACDNIGDB_00817 2e-94 3.6.1.55 L NUDIX domain
ACDNIGDB_00818 1.4e-152 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
ACDNIGDB_00819 3.9e-198 V Beta-lactamase
ACDNIGDB_00820 8.4e-63
ACDNIGDB_00821 0.0 L helicase activity
ACDNIGDB_00822 6.4e-227 K DNA binding
ACDNIGDB_00823 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
ACDNIGDB_00824 2.2e-247 mod 2.1.1.72, 3.1.21.5 L DNA methylase
ACDNIGDB_00825 7.4e-39 K Cro/C1-type HTH DNA-binding domain
ACDNIGDB_00826 1.1e-77
ACDNIGDB_00827 2.5e-114
ACDNIGDB_00828 2.6e-61
ACDNIGDB_00829 3.2e-36
ACDNIGDB_00830 1.3e-232
ACDNIGDB_00832 2.7e-23
ACDNIGDB_00833 4.9e-51
ACDNIGDB_00834 6.1e-221 L Protein of unknown function (DUF2800)
ACDNIGDB_00835 1.7e-99 S Protein of unknown function (DUF2815)
ACDNIGDB_00836 0.0 polA_2 2.7.7.7 L DNA polymerase
ACDNIGDB_00837 2.8e-69 S Psort location Cytoplasmic, score
ACDNIGDB_00838 0.0 S Phage plasmid primase, P4
ACDNIGDB_00839 2.4e-46 S VRR_NUC
ACDNIGDB_00840 4.3e-258 L SNF2 family N-terminal domain
ACDNIGDB_00841 2.8e-87
ACDNIGDB_00842 1.4e-36
ACDNIGDB_00843 2.2e-245 2.1.1.72 KL DNA methylase
ACDNIGDB_00844 3.5e-52 S Psort location Cytoplasmic, score
ACDNIGDB_00845 6.2e-31 S Domain of unknown function (DUF5049)
ACDNIGDB_00846 2.6e-302 S overlaps another CDS with the same product name
ACDNIGDB_00847 2.5e-247 S Phage portal protein
ACDNIGDB_00848 2.9e-122 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
ACDNIGDB_00849 4.1e-220 S Phage capsid family
ACDNIGDB_00850 4.3e-43 S Phage gp6-like head-tail connector protein
ACDNIGDB_00851 9e-68 S Phage head-tail joining protein
ACDNIGDB_00852 3e-69 S Bacteriophage holin family
ACDNIGDB_00853 2.5e-145 M Glycosyl hydrolases family 25
ACDNIGDB_00854 4.3e-36
ACDNIGDB_00855 3.1e-164 L Recombinase zinc beta ribbon domain
ACDNIGDB_00856 9.1e-101 L Recombinase zinc beta ribbon domain
ACDNIGDB_00857 1.2e-288 L Recombinase
ACDNIGDB_00858 2.7e-227
ACDNIGDB_00859 8.7e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACDNIGDB_00860 9.6e-121 spaE S ABC-2 family transporter protein
ACDNIGDB_00861 1.6e-108 mutF V ABC transporter, ATP-binding protein
ACDNIGDB_00862 1.3e-241 nhaC C Na H antiporter NhaC
ACDNIGDB_00863 6.2e-162 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
ACDNIGDB_00864 3.3e-95 S UPF0397 protein
ACDNIGDB_00865 0.0 ykoD P ABC transporter, ATP-binding protein
ACDNIGDB_00866 3.1e-142 cbiQ P cobalt transport
ACDNIGDB_00867 2.7e-118 ybhL S Belongs to the BI1 family
ACDNIGDB_00868 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
ACDNIGDB_00869 4.7e-64 S Domain of unknown function (DUF4430)
ACDNIGDB_00870 8.1e-88 S ECF transporter, substrate-specific component
ACDNIGDB_00871 2.1e-94 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
ACDNIGDB_00872 1.7e-128 L Helix-turn-helix domain
ACDNIGDB_00873 2.3e-23 L hmm pf00665
ACDNIGDB_00874 1.2e-39 L hmm pf00665
ACDNIGDB_00875 9.6e-152 S hydrolase
ACDNIGDB_00877 7.3e-169 yegS 2.7.1.107 G Lipid kinase
ACDNIGDB_00878 1.5e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACDNIGDB_00879 1.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ACDNIGDB_00880 4.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACDNIGDB_00881 1.7e-207 camS S sex pheromone
ACDNIGDB_00882 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACDNIGDB_00883 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
ACDNIGDB_00884 2.7e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
ACDNIGDB_00885 1.3e-100 S ECF transporter, substrate-specific component
ACDNIGDB_00887 7.4e-85 ydcK S Belongs to the SprT family
ACDNIGDB_00888 7e-135 M Glycosyltransferase sugar-binding region containing DXD motif
ACDNIGDB_00889 1.9e-256 epsU S Polysaccharide biosynthesis protein
ACDNIGDB_00890 4.7e-229 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ACDNIGDB_00891 7e-147
ACDNIGDB_00892 4.8e-102 V ABC transporter transmembrane region
ACDNIGDB_00893 4.9e-148 V ABC transporter transmembrane region
ACDNIGDB_00894 0.0 pacL 3.6.3.8 P P-type ATPase
ACDNIGDB_00895 3.6e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ACDNIGDB_00896 2.9e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACDNIGDB_00897 0.0 tuaG GT2 M Glycosyltransferase like family 2
ACDNIGDB_00898 2.9e-204 csaB M Glycosyl transferases group 1
ACDNIGDB_00899 4.2e-141 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
ACDNIGDB_00900 1.5e-67 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
ACDNIGDB_00901 4.7e-123 gntR1 K UTRA
ACDNIGDB_00902 9.3e-190
ACDNIGDB_00903 1.4e-52 P Rhodanese Homology Domain
ACDNIGDB_00906 9.9e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
ACDNIGDB_00907 1.8e-145 K SIS domain
ACDNIGDB_00908 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ACDNIGDB_00909 9.1e-12 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ACDNIGDB_00910 2e-100 nusG K Participates in transcription elongation, termination and antitermination
ACDNIGDB_00911 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACDNIGDB_00912 1.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ACDNIGDB_00913 4.6e-109 glnP P ABC transporter permease
ACDNIGDB_00914 8.8e-116 glnQ 3.6.3.21 E ABC transporter
ACDNIGDB_00915 6.2e-148 aatB ET ABC transporter substrate-binding protein
ACDNIGDB_00916 3.1e-96 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACDNIGDB_00917 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ACDNIGDB_00918 1.8e-148 kcsA P Ion transport protein
ACDNIGDB_00919 1.6e-32
ACDNIGDB_00920 3.9e-113 rsmC 2.1.1.172 J Methyltransferase
ACDNIGDB_00921 1.9e-23
ACDNIGDB_00922 8.4e-81 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ACDNIGDB_00923 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACDNIGDB_00924 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACDNIGDB_00925 6.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACDNIGDB_00926 6.9e-26 S Protein of unknown function (DUF2508)
ACDNIGDB_00927 3.7e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACDNIGDB_00928 4.5e-52 yaaQ S Cyclic-di-AMP receptor
ACDNIGDB_00929 2.8e-154 holB 2.7.7.7 L DNA polymerase III
ACDNIGDB_00930 1.3e-57 yabA L Involved in initiation control of chromosome replication
ACDNIGDB_00931 1.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACDNIGDB_00932 8.1e-126 fat 3.1.2.21 I Acyl-ACP thioesterase
ACDNIGDB_00933 9.8e-86 folT S ECF transporter, substrate-specific component
ACDNIGDB_00934 1.5e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
ACDNIGDB_00935 2.4e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
ACDNIGDB_00936 2.1e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACDNIGDB_00937 4.3e-09 D nuclear chromosome segregation
ACDNIGDB_00938 8.4e-10 D nuclear chromosome segregation
ACDNIGDB_00939 3.8e-170
ACDNIGDB_00940 2.7e-114
ACDNIGDB_00941 6.7e-240 clcA P chloride
ACDNIGDB_00942 4.5e-48
ACDNIGDB_00943 2.1e-99 S Protein of unknown function (DUF3990)
ACDNIGDB_00944 2e-158 ykuT M mechanosensitive ion channel
ACDNIGDB_00945 5.9e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACDNIGDB_00946 2.2e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACDNIGDB_00947 6.5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ACDNIGDB_00948 2.4e-68 yslB S Protein of unknown function (DUF2507)
ACDNIGDB_00949 6.6e-53 trxA O Belongs to the thioredoxin family
ACDNIGDB_00950 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ACDNIGDB_00951 1.6e-91 cvpA S Colicin V production protein
ACDNIGDB_00952 1.8e-50 yrzB S Belongs to the UPF0473 family
ACDNIGDB_00953 1.4e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACDNIGDB_00954 2.6e-42 yrzL S Belongs to the UPF0297 family
ACDNIGDB_00955 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACDNIGDB_00956 1.5e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ACDNIGDB_00957 2.5e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
ACDNIGDB_00958 1.4e-209 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACDNIGDB_00959 1.4e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACDNIGDB_00960 4.5e-31 yajC U Preprotein translocase
ACDNIGDB_00961 1.4e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ACDNIGDB_00962 1.6e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ACDNIGDB_00963 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACDNIGDB_00964 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACDNIGDB_00965 0.0 nisT V ABC transporter
ACDNIGDB_00966 5.1e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACDNIGDB_00967 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACDNIGDB_00968 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACDNIGDB_00969 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
ACDNIGDB_00970 1.7e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ACDNIGDB_00971 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACDNIGDB_00972 1.6e-155 corA P CorA-like Mg2+ transporter protein
ACDNIGDB_00973 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
ACDNIGDB_00974 4.8e-76 rplI J Binds to the 23S rRNA
ACDNIGDB_00975 1.1e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ACDNIGDB_00976 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
ACDNIGDB_00977 1.6e-131 I Protein of unknown function (DUF2974)
ACDNIGDB_00978 4.5e-70 I Protein of unknown function (DUF2974)
ACDNIGDB_00979 0.0
ACDNIGDB_00980 3.9e-117 yhiD S MgtC family
ACDNIGDB_00982 7.9e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
ACDNIGDB_00983 1.2e-20 WQ51_00220 K Helix-turn-helix XRE-family like proteins
ACDNIGDB_00984 1.3e-85 S Protein of unknown function (DUF3278)
ACDNIGDB_00985 4.9e-201 S Aldo keto reductase
ACDNIGDB_00987 4.6e-224 S Sterol carrier protein domain
ACDNIGDB_00988 3e-116 ywnB S NAD(P)H-binding
ACDNIGDB_00989 4.2e-08 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
ACDNIGDB_00990 7e-295 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ACDNIGDB_00991 9.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACDNIGDB_00992 1.7e-123 liaI S membrane
ACDNIGDB_00993 1e-78 XK27_02470 K LytTr DNA-binding domain
ACDNIGDB_00994 3e-104 yvdD 3.2.2.10 S Belongs to the LOG family
ACDNIGDB_00995 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ACDNIGDB_00996 0.0 uup S ABC transporter, ATP-binding protein
ACDNIGDB_00997 8.3e-68
ACDNIGDB_00998 9.3e-155 K Helix-turn-helix XRE-family like proteins
ACDNIGDB_00999 7.6e-249 scrB 2.7.1.211, 3.2.1.26 GH32 G Glycosyl hydrolases family 32
ACDNIGDB_01000 2.9e-40 scrB 2.7.1.211, 3.2.1.26 GH32 G Glycosyl hydrolases family 32
ACDNIGDB_01001 0.0 scrA 2.7.1.211 G phosphotransferase system
ACDNIGDB_01002 2.7e-188 bglX 3.2.1.21 GH3 G hydrolase, family 3
ACDNIGDB_01003 1.1e-228 bglX 3.2.1.21 GH3 G hydrolase, family 3
ACDNIGDB_01004 6.3e-193 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ACDNIGDB_01005 3.3e-228 G Major Facilitator Superfamily
ACDNIGDB_01006 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACDNIGDB_01007 1.7e-210 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ACDNIGDB_01008 1.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
ACDNIGDB_01009 1.7e-34
ACDNIGDB_01010 4.2e-98 yvrI K sigma factor activity
ACDNIGDB_01011 5.3e-291 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
ACDNIGDB_01012 8.3e-291 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
ACDNIGDB_01013 1.9e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
ACDNIGDB_01014 2e-152 lacT K PRD domain
ACDNIGDB_01015 1.2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACDNIGDB_01016 1.7e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ACDNIGDB_01017 3.4e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
ACDNIGDB_01018 3.1e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACDNIGDB_01019 1.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACDNIGDB_01020 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
ACDNIGDB_01021 2.1e-257 pepC 3.4.22.40 E Peptidase C1-like family
ACDNIGDB_01022 2.6e-185 S AAA domain
ACDNIGDB_01023 1.7e-165 S Protein of unknown function DUF262
ACDNIGDB_01024 0.0 1.3.5.4 C FMN_bind
ACDNIGDB_01025 7.2e-92
ACDNIGDB_01026 9.2e-109
ACDNIGDB_01027 3.8e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACDNIGDB_01028 6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ACDNIGDB_01029 7.6e-115 hlyIII S protein, hemolysin III
ACDNIGDB_01030 3.8e-151 DegV S Uncharacterised protein, DegV family COG1307
ACDNIGDB_01031 2e-35 yozE S Belongs to the UPF0346 family
ACDNIGDB_01032 1.1e-264 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
ACDNIGDB_01033 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ACDNIGDB_01034 9.8e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACDNIGDB_01035 2.6e-152 dprA LU DNA protecting protein DprA
ACDNIGDB_01036 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACDNIGDB_01037 2.7e-244 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ACDNIGDB_01038 2e-169 xerC D Phage integrase, N-terminal SAM-like domain
ACDNIGDB_01039 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACDNIGDB_01040 8.2e-252 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ACDNIGDB_01041 4.2e-177 lacX 5.1.3.3 G Aldose 1-epimerase
ACDNIGDB_01042 2.6e-98 K LysR substrate binding domain
ACDNIGDB_01043 2.2e-229 XK27_04775 S PAS domain
ACDNIGDB_01044 6.4e-105 S Iron-sulfur cluster assembly protein
ACDNIGDB_01045 5.3e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ACDNIGDB_01046 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
ACDNIGDB_01047 1.2e-64
ACDNIGDB_01048 7.3e-266 yxbA 6.3.1.12 S ATP-grasp enzyme
ACDNIGDB_01049 0.0 asnB 6.3.5.4 E Asparagine synthase
ACDNIGDB_01050 1.8e-275 S Calcineurin-like phosphoesterase
ACDNIGDB_01051 7.3e-83
ACDNIGDB_01052 5.4e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
ACDNIGDB_01053 1.6e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
ACDNIGDB_01054 4.3e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ACDNIGDB_01055 9.8e-169 phnD P Phosphonate ABC transporter
ACDNIGDB_01057 3.8e-87 uspA T universal stress protein
ACDNIGDB_01058 2e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
ACDNIGDB_01059 4.4e-132 XK27_08440 K UTRA domain
ACDNIGDB_01060 4.9e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ACDNIGDB_01061 7.4e-88 ntd 2.4.2.6 F Nucleoside
ACDNIGDB_01062 1.4e-189
ACDNIGDB_01063 2.3e-207 S zinc-ribbon domain
ACDNIGDB_01065 1.1e-149 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
ACDNIGDB_01066 1.7e-59 yjgN S Bacterial protein of unknown function (DUF898)
ACDNIGDB_01068 3.9e-93 M LysM domain protein
ACDNIGDB_01069 3.9e-110 M LysM domain protein
ACDNIGDB_01070 2.3e-133 S Putative ABC-transporter type IV
ACDNIGDB_01071 5.8e-49 psiE S Phosphate-starvation-inducible E
ACDNIGDB_01072 7.9e-75 K acetyltransferase
ACDNIGDB_01073 2.2e-180 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ACDNIGDB_01074 2.5e-195 G Psort location CytoplasmicMembrane, score 10.00
ACDNIGDB_01075 1.4e-36 licT K CAT RNA binding domain
ACDNIGDB_01076 1e-19 licT K transcriptional antiterminator
ACDNIGDB_01077 4.8e-131 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ACDNIGDB_01078 7.3e-217 L Belongs to the 'phage' integrase family
ACDNIGDB_01079 7.7e-15
ACDNIGDB_01080 9.5e-91 repB EP Plasmid replication protein
ACDNIGDB_01082 1.7e-132 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
ACDNIGDB_01083 1.3e-24
ACDNIGDB_01084 2.2e-18 K Helix-turn-helix XRE-family like proteins
ACDNIGDB_01086 5.1e-164 yvgN C Aldo keto reductase
ACDNIGDB_01087 6.8e-248 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
ACDNIGDB_01088 1.5e-115 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
ACDNIGDB_01089 1.5e-83 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
ACDNIGDB_01090 2.9e-232 S Peptidase M16
ACDNIGDB_01091 1.6e-129 IQ Enoyl-(Acyl carrier protein) reductase
ACDNIGDB_01092 4.3e-125 ymfM S Helix-turn-helix domain
ACDNIGDB_01093 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACDNIGDB_01094 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACDNIGDB_01095 1.2e-209 rny S Endoribonuclease that initiates mRNA decay
ACDNIGDB_01096 2.7e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
ACDNIGDB_01097 2.5e-118 yvyE 3.4.13.9 S YigZ family
ACDNIGDB_01098 1.1e-242 comFA L Helicase C-terminal domain protein
ACDNIGDB_01099 5.7e-126 comFC S Competence protein
ACDNIGDB_01100 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACDNIGDB_01101 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ACDNIGDB_01102 6.2e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACDNIGDB_01103 2.5e-35
ACDNIGDB_01104 3.8e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ACDNIGDB_01105 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACDNIGDB_01106 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
ACDNIGDB_01107 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ACDNIGDB_01108 6.9e-83 yebR 1.8.4.14 T GAF domain-containing protein
ACDNIGDB_01109 1.1e-107 ylbE GM NAD(P)H-binding
ACDNIGDB_01110 6e-128 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
ACDNIGDB_01111 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ACDNIGDB_01113 5.8e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
ACDNIGDB_01114 9e-77 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
ACDNIGDB_01115 2.4e-50
ACDNIGDB_01116 6.5e-173 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
ACDNIGDB_01117 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ACDNIGDB_01118 6.1e-171 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ACDNIGDB_01119 2.4e-124 M ErfK YbiS YcfS YnhG
ACDNIGDB_01120 4.3e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACDNIGDB_01121 7.5e-119
ACDNIGDB_01122 1.4e-214 I Protein of unknown function (DUF2974)
ACDNIGDB_01123 3.9e-301 ytgP S Polysaccharide biosynthesis protein
ACDNIGDB_01124 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ACDNIGDB_01125 5.9e-82 3.6.1.27 I Acid phosphatase homologues
ACDNIGDB_01126 3.2e-259 qacA EGP Major facilitator Superfamily
ACDNIGDB_01127 4.8e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACDNIGDB_01131 8.9e-139 glcR K DeoR C terminal sensor domain
ACDNIGDB_01132 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
ACDNIGDB_01133 1.6e-120 C nitroreductase
ACDNIGDB_01134 1.1e-132
ACDNIGDB_01135 3.6e-252 yhdP S Transporter associated domain
ACDNIGDB_01136 6.3e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ACDNIGDB_01137 1.9e-234 potE E amino acid
ACDNIGDB_01138 2.6e-137 M Glycosyl hydrolases family 25
ACDNIGDB_01139 4.1e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
ACDNIGDB_01140 2.1e-249 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ACDNIGDB_01143 6.5e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ACDNIGDB_01144 2e-86 gtcA S Teichoic acid glycosylation protein
ACDNIGDB_01145 4.2e-77 fld C Flavodoxin
ACDNIGDB_01146 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
ACDNIGDB_01147 1.6e-166 yihY S Belongs to the UPF0761 family
ACDNIGDB_01148 8.7e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ACDNIGDB_01149 6.1e-154 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ACDNIGDB_01150 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
ACDNIGDB_01151 4.6e-76 WQ51_03320 S Protein of unknown function (DUF1149)
ACDNIGDB_01152 1.7e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ACDNIGDB_01153 5.4e-212 yubA S AI-2E family transporter
ACDNIGDB_01154 9.9e-67 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
ACDNIGDB_01155 4.8e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
ACDNIGDB_01156 3.9e-234 N Uncharacterized conserved protein (DUF2075)
ACDNIGDB_01157 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
ACDNIGDB_01158 3.7e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ACDNIGDB_01159 5.2e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACDNIGDB_01160 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
ACDNIGDB_01161 3.3e-112 yjbK S CYTH
ACDNIGDB_01162 7e-107 yjbH Q Thioredoxin
ACDNIGDB_01163 1.7e-162 coiA 3.6.4.12 S Competence protein
ACDNIGDB_01164 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
ACDNIGDB_01165 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ACDNIGDB_01166 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACDNIGDB_01167 1.2e-39 ptsH G phosphocarrier protein HPR
ACDNIGDB_01168 2.8e-113 S domain, Protein
ACDNIGDB_01169 0.0 S domain, Protein
ACDNIGDB_01170 5.3e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACDNIGDB_01171 5.2e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
ACDNIGDB_01172 6.2e-213 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ACDNIGDB_01173 1e-251 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
ACDNIGDB_01174 3e-166 K AI-2E family transporter
ACDNIGDB_01175 1.8e-40
ACDNIGDB_01176 2.2e-165 S Alpha beta hydrolase
ACDNIGDB_01177 0.0 L Helicase C-terminal domain protein
ACDNIGDB_01178 5.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
ACDNIGDB_01179 2.5e-40 S Transglycosylase associated protein
ACDNIGDB_01181 1.2e-70 P CorA-like Mg2+ transporter protein
ACDNIGDB_01182 8.7e-63 P CorA-like Mg2+ transporter protein
ACDNIGDB_01183 0.0 tetP J elongation factor G
ACDNIGDB_01184 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ACDNIGDB_01185 7e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACDNIGDB_01186 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
ACDNIGDB_01187 6.6e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ACDNIGDB_01188 3.7e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ACDNIGDB_01189 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACDNIGDB_01190 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ACDNIGDB_01191 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
ACDNIGDB_01192 6.6e-270 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ACDNIGDB_01193 5.8e-291 clcA P chloride
ACDNIGDB_01194 1.2e-201 EGP Major facilitator Superfamily
ACDNIGDB_01195 1.7e-151 ropB K Transcriptional regulator
ACDNIGDB_01196 2.2e-107
ACDNIGDB_01197 1.5e-115 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
ACDNIGDB_01198 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ACDNIGDB_01199 6.5e-69 S Iron-sulphur cluster biosynthesis
ACDNIGDB_01200 2.3e-232 EGP Sugar (and other) transporter
ACDNIGDB_01201 2.3e-75 K Acetyltransferase (GNAT) domain
ACDNIGDB_01202 1e-248 ynbB 4.4.1.1 P aluminum resistance
ACDNIGDB_01203 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
ACDNIGDB_01204 4.1e-286 E Amino acid permease
ACDNIGDB_01205 0.0 pepO 3.4.24.71 O Peptidase family M13
ACDNIGDB_01206 4.4e-155 ropB K Helix-turn-helix XRE-family like proteins
ACDNIGDB_01207 0.0 copA 3.6.3.54 P P-type ATPase
ACDNIGDB_01208 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ACDNIGDB_01209 6.3e-66 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ACDNIGDB_01210 1.4e-77 atkY K Penicillinase repressor
ACDNIGDB_01211 5.5e-90
ACDNIGDB_01212 4.1e-90
ACDNIGDB_01213 3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
ACDNIGDB_01214 1.1e-226 pbuG S permease
ACDNIGDB_01215 3.4e-46 I bis(5'-adenosyl)-triphosphatase activity
ACDNIGDB_01216 2.3e-232 pbuG S permease
ACDNIGDB_01217 3.7e-110 K helix_turn_helix, mercury resistance
ACDNIGDB_01219 3e-232 pbuG S permease
ACDNIGDB_01220 6e-238 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
ACDNIGDB_01221 8.2e-125 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
ACDNIGDB_01222 7.7e-120 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
ACDNIGDB_01223 1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ACDNIGDB_01224 9.8e-160 yeaE S Aldo/keto reductase family
ACDNIGDB_01225 3.6e-19 S PD-(D/E)XK nuclease family transposase
ACDNIGDB_01226 4.6e-150 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
ACDNIGDB_01227 1.1e-91 agaC G PTS system sorbose-specific iic component
ACDNIGDB_01228 1e-121 G PTS system mannose/fructose/sorbose family IID component
ACDNIGDB_01229 2.2e-27 G PTS system fructose IIA component
ACDNIGDB_01230 1.2e-132 S membrane transporter protein
ACDNIGDB_01231 2e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ACDNIGDB_01232 4.1e-130 3.5.2.6 V Beta-lactamase enzyme family
ACDNIGDB_01233 5.7e-189 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
ACDNIGDB_01234 3.2e-88 blaA6 V Beta-lactamase
ACDNIGDB_01235 1.3e-52 2.7.1.191 G PTS system sorbose subfamily IIB component
ACDNIGDB_01236 1e-119 G PTS system mannose/fructose/sorbose family IID component
ACDNIGDB_01237 2e-99 G PTS system sorbose-specific iic component
ACDNIGDB_01238 7e-177 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
ACDNIGDB_01239 4.8e-173 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
ACDNIGDB_01240 7.1e-195 tcsA S ABC transporter substrate-binding protein PnrA-like
ACDNIGDB_01241 1.2e-166 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
ACDNIGDB_01242 1.1e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
ACDNIGDB_01243 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ACDNIGDB_01244 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
ACDNIGDB_01245 2.2e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
ACDNIGDB_01246 8.7e-270 cydA 1.10.3.14 C ubiquinol oxidase
ACDNIGDB_01247 0.0 macB_3 V ABC transporter, ATP-binding protein
ACDNIGDB_01248 1.5e-195 S DUF218 domain
ACDNIGDB_01249 6.5e-103 S CAAX protease self-immunity
ACDNIGDB_01250 2.2e-93 S Protein of unknown function (DUF1440)
ACDNIGDB_01251 4.5e-269 G PTS system Galactitol-specific IIC component
ACDNIGDB_01252 2.7e-234 G PTS system sugar-specific permease component
ACDNIGDB_01253 2.3e-114 S Protein of unknown function (DUF969)
ACDNIGDB_01254 3.8e-157 S Protein of unknown function (DUF979)
ACDNIGDB_01255 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ACDNIGDB_01256 2.1e-30
ACDNIGDB_01257 4.1e-31
ACDNIGDB_01258 6.2e-28
ACDNIGDB_01259 8.5e-159 mutR K Helix-turn-helix XRE-family like proteins
ACDNIGDB_01260 2.7e-280 V ABC transporter transmembrane region
ACDNIGDB_01262 3.5e-200 napA P Sodium/hydrogen exchanger family
ACDNIGDB_01263 0.0 cadA P P-type ATPase
ACDNIGDB_01264 1.9e-83 ykuL S (CBS) domain
ACDNIGDB_01265 5.9e-19
ACDNIGDB_01266 5.9e-40
ACDNIGDB_01267 6e-61 yugI 5.3.1.9 J general stress protein
ACDNIGDB_01268 4.8e-179 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
ACDNIGDB_01269 2.7e-117 dedA S SNARE-like domain protein
ACDNIGDB_01270 8.6e-105 S Protein of unknown function (DUF1461)
ACDNIGDB_01271 3.6e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ACDNIGDB_01272 9.1e-98 yutD S Protein of unknown function (DUF1027)
ACDNIGDB_01273 3.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
ACDNIGDB_01274 2e-55
ACDNIGDB_01275 8e-268 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ACDNIGDB_01276 2.4e-275 pepV 3.5.1.18 E dipeptidase PepV
ACDNIGDB_01277 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
ACDNIGDB_01278 9.5e-178 ccpA K catabolite control protein A
ACDNIGDB_01279 5.9e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ACDNIGDB_01280 4e-51
ACDNIGDB_01283 1.3e-40
ACDNIGDB_01284 1.5e-231 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ACDNIGDB_01285 1.2e-36 S RelB antitoxin
ACDNIGDB_01286 7.4e-43
ACDNIGDB_01287 2.5e-25 L Helix-turn-helix domain
ACDNIGDB_01288 0.0 surA 2.4.1.129, 3.4.16.4 GT51 S Rib/alpha-like repeat
ACDNIGDB_01289 1.4e-17 L Transposase, IS116 IS110 IS902 family
ACDNIGDB_01290 5e-56 L Transposase, IS116 IS110 IS902 family
ACDNIGDB_01291 4.1e-147 S hydrolase
ACDNIGDB_01292 3.2e-103 yagU S Protein of unknown function (DUF1440)
ACDNIGDB_01293 5.4e-144 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
ACDNIGDB_01294 1.5e-76 2.3.1.128 K acetyltransferase
ACDNIGDB_01295 0.0 4.2.1.53 S Myosin-crossreactive antigen
ACDNIGDB_01296 4.9e-69 yxdD K Bacterial regulatory proteins, tetR family
ACDNIGDB_01297 4.5e-261 emrY EGP Major facilitator Superfamily
ACDNIGDB_01298 6.4e-255 emrY EGP Major facilitator Superfamily
ACDNIGDB_01299 1.4e-144 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
ACDNIGDB_01300 2.3e-134 S CAAX amino terminal protease
ACDNIGDB_01301 6.9e-162 mleP3 S Membrane transport protein
ACDNIGDB_01302 2.1e-105 tag 3.2.2.20 L glycosylase
ACDNIGDB_01303 4.2e-194 S Bacteriocin helveticin-J
ACDNIGDB_01304 0.0 M domain protein
ACDNIGDB_01305 0.0 bamA UW LPXTG-motif cell wall anchor domain protein
ACDNIGDB_01306 3.9e-23 bamA UW LPXTG-motif cell wall anchor domain protein
ACDNIGDB_01308 0.0 S domain, Protein
ACDNIGDB_01309 0.0 lhr L DEAD DEAH box helicase
ACDNIGDB_01310 5.4e-253 P P-loop Domain of unknown function (DUF2791)
ACDNIGDB_01311 0.0 S TerB-C domain
ACDNIGDB_01312 1.3e-99 4.1.1.44 S decarboxylase
ACDNIGDB_01313 5.1e-72
ACDNIGDB_01314 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
ACDNIGDB_01315 4.9e-233 cycA E Amino acid permease
ACDNIGDB_01316 2.4e-108 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
ACDNIGDB_01317 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACDNIGDB_01318 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACDNIGDB_01319 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ACDNIGDB_01321 1.6e-08
ACDNIGDB_01322 2e-52 S Enterocin A Immunity
ACDNIGDB_01323 4e-133 gntR K UbiC transcription regulator-associated domain protein
ACDNIGDB_01324 4.1e-175 rihB 3.2.2.1 F Nucleoside
ACDNIGDB_01325 4.8e-128 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACDNIGDB_01326 3.2e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACDNIGDB_01328 1.7e-84 dps P Belongs to the Dps family
ACDNIGDB_01329 2.2e-282 S C4-dicarboxylate anaerobic carrier
ACDNIGDB_01330 2.6e-118 phoU P Plays a role in the regulation of phosphate uptake
ACDNIGDB_01331 2.7e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ACDNIGDB_01332 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ACDNIGDB_01333 5.4e-156 pstA P Phosphate transport system permease protein PstA
ACDNIGDB_01334 2.1e-161 pstC P probably responsible for the translocation of the substrate across the membrane
ACDNIGDB_01335 1.3e-159 pstS P Phosphate
ACDNIGDB_01336 6.2e-96 K Acetyltransferase (GNAT) domain
ACDNIGDB_01337 3.8e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ACDNIGDB_01338 4.1e-257 glnPH2 P ABC transporter permease
ACDNIGDB_01339 4.8e-159 rssA S Phospholipase, patatin family
ACDNIGDB_01340 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
ACDNIGDB_01341 6.8e-56 S Enterocin A Immunity
ACDNIGDB_01343 1.9e-205 EGP Major facilitator superfamily
ACDNIGDB_01344 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
ACDNIGDB_01345 8.3e-84 S Putative adhesin
ACDNIGDB_01346 0.0 treB 2.7.1.211 G phosphotransferase system
ACDNIGDB_01347 1.1e-130 treR K UTRA
ACDNIGDB_01348 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
ACDNIGDB_01349 4.8e-151 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ACDNIGDB_01350 2e-107 glnP P ABC transporter permease
ACDNIGDB_01351 3.2e-110 gluC P ABC transporter permease
ACDNIGDB_01352 9.1e-150 glnH ET ABC transporter
ACDNIGDB_01353 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ACDNIGDB_01354 1.3e-148 glnH ET ABC transporter
ACDNIGDB_01355 0.0 V ABC transporter transmembrane region
ACDNIGDB_01356 0.0 XK27_09600 V ABC transporter, ATP-binding protein
ACDNIGDB_01357 1.9e-59 K Transcriptional regulator, MarR family
ACDNIGDB_01358 7.9e-152 S Alpha beta hydrolase
ACDNIGDB_01359 2.9e-208 naiP EGP Major facilitator Superfamily
ACDNIGDB_01360 1.6e-266 dtpT U amino acid peptide transporter
ACDNIGDB_01361 0.0 3.2.1.177 GH31 G Glycosyl hydrolases family 31
ACDNIGDB_01362 8.2e-182 lacI3 K helix_turn _helix lactose operon repressor
ACDNIGDB_01363 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
ACDNIGDB_01364 6.8e-72 2.7.1.191 G PTS system fructose IIA component
ACDNIGDB_01365 3.4e-152 G PTS system mannose/fructose/sorbose family IID component
ACDNIGDB_01366 4.7e-103 G PTS system sorbose-specific iic component
ACDNIGDB_01367 5.9e-88 2.7.1.191 G PTS system sorbose subfamily IIB component
ACDNIGDB_01369 2.7e-210 pepA E M42 glutamyl aminopeptidase
ACDNIGDB_01370 5.8e-82
ACDNIGDB_01371 6.1e-73 K helix_turn_helix multiple antibiotic resistance protein
ACDNIGDB_01372 1.5e-32
ACDNIGDB_01373 1.9e-217 mdtG EGP Major facilitator Superfamily
ACDNIGDB_01374 3.3e-112 3.6.1.27 I Acid phosphatase homologues
ACDNIGDB_01375 2.1e-67 glsA 3.5.1.2 E Belongs to the glutaminase family
ACDNIGDB_01376 1.2e-83 glsA 3.5.1.2 E Belongs to the glutaminase family
ACDNIGDB_01377 3.7e-260 P Sodium:sulfate symporter transmembrane region
ACDNIGDB_01378 0.0 1.3.5.4 C FMN_bind
ACDNIGDB_01379 8.2e-165 K LysR family
ACDNIGDB_01380 3e-201 S PFAM Archaeal ATPase
ACDNIGDB_01381 2.7e-99 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
ACDNIGDB_01382 3.2e-177 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
ACDNIGDB_01383 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
ACDNIGDB_01384 8.7e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
ACDNIGDB_01385 2.1e-149 lacT K CAT RNA binding domain
ACDNIGDB_01386 1.3e-38
ACDNIGDB_01387 1.4e-267 gatC G PTS system sugar-specific permease component
ACDNIGDB_01388 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
ACDNIGDB_01389 7.2e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ACDNIGDB_01390 1.6e-128 S Domain of unknown function (DUF4867)
ACDNIGDB_01391 1.9e-106 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
ACDNIGDB_01392 9.4e-74 lacA 5.3.1.26 G Ribose/Galactose Isomerase
ACDNIGDB_01393 1.3e-137 lacR K DeoR C terminal sensor domain
ACDNIGDB_01394 2.1e-241 pyrP F Permease
ACDNIGDB_01395 5.2e-25 S PFAM Archaeal ATPase
ACDNIGDB_01397 1.5e-21 K DNA-binding transcription factor activity
ACDNIGDB_01398 4.4e-139 G Pts system
ACDNIGDB_01399 1e-182 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ACDNIGDB_01401 9.3e-54 K Transcriptional regulator
ACDNIGDB_01402 6.2e-104 S Protein of unknown function (DUF1211)
ACDNIGDB_01403 8.7e-75 K LytTr DNA-binding domain
ACDNIGDB_01404 1.4e-50 S Protein of unknown function (DUF3021)
ACDNIGDB_01405 9.6e-97 K Acetyltransferase (GNAT) domain
ACDNIGDB_01406 2.1e-129 ybbM S Uncharacterised protein family (UPF0014)
ACDNIGDB_01407 2.1e-109 ybbL S ABC transporter, ATP-binding protein
ACDNIGDB_01409 2e-74 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ACDNIGDB_01410 1.7e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ACDNIGDB_01411 1.8e-41 K peptidyl-tyrosine sulfation
ACDNIGDB_01412 2.6e-42
ACDNIGDB_01413 5.4e-47
ACDNIGDB_01414 5.9e-70 K Transcriptional regulator
ACDNIGDB_01415 8.9e-179 MA20_14895 S Conserved hypothetical protein 698
ACDNIGDB_01416 1.2e-63
ACDNIGDB_01417 1.4e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ACDNIGDB_01418 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACDNIGDB_01419 1.3e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACDNIGDB_01420 2.3e-78 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
ACDNIGDB_01421 1.2e-48 L bacterial-type proximal promoter sequence-specific DNA binding
ACDNIGDB_01422 1.7e-53 S Bacterial toxin of type II toxin-antitoxin system, YafQ
ACDNIGDB_01423 5e-234 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
ACDNIGDB_01424 6.7e-153 K helix_turn_helix, arabinose operon control protein
ACDNIGDB_01425 1e-16 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ACDNIGDB_01426 3.4e-42 3.6.4.12 S PD-(D/E)XK nuclease family transposase
ACDNIGDB_01427 1.7e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ACDNIGDB_01428 3.9e-226 ecsB U ABC transporter
ACDNIGDB_01429 2.4e-133 ecsA V ABC transporter, ATP-binding protein
ACDNIGDB_01430 2.4e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
ACDNIGDB_01431 2e-64
ACDNIGDB_01432 4.4e-37 S YtxH-like protein
ACDNIGDB_01433 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ACDNIGDB_01435 4.7e-88 comGF U Putative Competence protein ComGF
ACDNIGDB_01436 1.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
ACDNIGDB_01437 7.3e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACDNIGDB_01440 6.7e-225 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
ACDNIGDB_01447 4.2e-217 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
ACDNIGDB_01448 3.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
ACDNIGDB_01449 4.5e-183 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACDNIGDB_01450 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ACDNIGDB_01451 0.0 3.6.3.8 P ATPase, P-type (transporting), HAD superfamily, subfamily IC
ACDNIGDB_01453 6.2e-80 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
ACDNIGDB_01454 7.1e-132 S Protein of unknown function (DUF975)
ACDNIGDB_01455 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
ACDNIGDB_01456 5.2e-153 yitS S EDD domain protein, DegV family
ACDNIGDB_01457 2.2e-19
ACDNIGDB_01458 1.5e-189 L COG2963 Transposase and inactivated derivatives
ACDNIGDB_01459 6.9e-26
ACDNIGDB_01460 0.0 clpE O Belongs to the ClpA ClpB family
ACDNIGDB_01461 4.3e-43 XK27_09445 S Domain of unknown function (DUF1827)
ACDNIGDB_01462 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACDNIGDB_01463 4.7e-157 hlyX S Transporter associated domain
ACDNIGDB_01464 3e-78
ACDNIGDB_01465 4.9e-90
ACDNIGDB_01466 2.4e-112 ygaC J Belongs to the UPF0374 family
ACDNIGDB_01467 7.8e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
ACDNIGDB_01468 9.2e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACDNIGDB_01469 2.9e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
ACDNIGDB_01470 3.9e-221 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
ACDNIGDB_01471 6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
ACDNIGDB_01472 8.1e-179 D Alpha beta
ACDNIGDB_01473 2.4e-07
ACDNIGDB_01474 4.3e-152 S haloacid dehalogenase-like hydrolase
ACDNIGDB_01475 2.8e-205 EGP Major facilitator Superfamily
ACDNIGDB_01476 1.1e-261 glnA 6.3.1.2 E glutamine synthetase
ACDNIGDB_01477 9.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACDNIGDB_01478 1.1e-18 S Protein of unknown function (DUF3042)
ACDNIGDB_01479 1.5e-57 yqhL P Rhodanese-like protein
ACDNIGDB_01480 6e-35 yqgQ S Bacterial protein of unknown function (DUF910)
ACDNIGDB_01481 4.5e-118 gluP 3.4.21.105 S Rhomboid family
ACDNIGDB_01482 5.6e-87 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACDNIGDB_01483 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ACDNIGDB_01484 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
ACDNIGDB_01485 0.0 S membrane
ACDNIGDB_01486 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ACDNIGDB_01487 2.9e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACDNIGDB_01488 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ACDNIGDB_01489 8.1e-204 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACDNIGDB_01490 7.3e-64 yodB K Transcriptional regulator, HxlR family
ACDNIGDB_01491 9.6e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACDNIGDB_01492 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
ACDNIGDB_01493 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ACDNIGDB_01494 1.9e-281 arlS 2.7.13.3 T Histidine kinase
ACDNIGDB_01495 1.1e-130 K response regulator
ACDNIGDB_01496 2.9e-96 yceD S Uncharacterized ACR, COG1399
ACDNIGDB_01497 2.2e-218 ylbM S Belongs to the UPF0348 family
ACDNIGDB_01498 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ACDNIGDB_01499 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
ACDNIGDB_01500 4.4e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACDNIGDB_01501 4.7e-210 yqeH S Ribosome biogenesis GTPase YqeH
ACDNIGDB_01502 3.5e-91 yqeG S HAD phosphatase, family IIIA
ACDNIGDB_01503 9.8e-191 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACDNIGDB_01504 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACDNIGDB_01505 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
ACDNIGDB_01506 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACDNIGDB_01507 1.3e-131 S domain protein
ACDNIGDB_01508 4.8e-171 V ABC transporter
ACDNIGDB_01509 1.9e-74 S Protein of unknown function (DUF3021)
ACDNIGDB_01510 1.4e-72 K LytTr DNA-binding domain
ACDNIGDB_01511 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACDNIGDB_01512 2.7e-163 dnaI L Primosomal protein DnaI
ACDNIGDB_01513 2.5e-250 dnaB L Replication initiation and membrane attachment
ACDNIGDB_01514 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACDNIGDB_01515 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACDNIGDB_01516 1.1e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ACDNIGDB_01517 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACDNIGDB_01518 5.7e-230 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
ACDNIGDB_01519 1.4e-211 EGP Major facilitator Superfamily
ACDNIGDB_01520 4e-69 rmaI K Transcriptional regulator
ACDNIGDB_01521 5.9e-12
ACDNIGDB_01522 1.4e-75 K UTRA
ACDNIGDB_01523 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
ACDNIGDB_01524 1.2e-117 cutC P Participates in the control of copper homeostasis
ACDNIGDB_01525 4.1e-150 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ACDNIGDB_01526 5.6e-55 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ACDNIGDB_01527 2.9e-93 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
ACDNIGDB_01528 3.3e-180 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
ACDNIGDB_01529 8.2e-254 3.5.1.18 E Peptidase family M20/M25/M40
ACDNIGDB_01530 2.7e-129 ymfC K UTRA
ACDNIGDB_01531 4.8e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ACDNIGDB_01532 6.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ACDNIGDB_01536 5e-60
ACDNIGDB_01538 2.8e-31 I Protein of unknown function (DUF2974)
ACDNIGDB_01550 5.6e-149 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ACDNIGDB_01551 1.4e-66 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)