ORF_ID e_value Gene_name EC_number CAZy COGs Description
HPEHFLOH_00001 1.7e-43 ankB S ankyrin repeats
HPEHFLOH_00002 2.1e-31
HPEHFLOH_00003 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HPEHFLOH_00004 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPEHFLOH_00005 4.1e-150 bla1 3.5.2.6 V Beta-lactamase enzyme family
HPEHFLOH_00006 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPEHFLOH_00007 2.6e-183 S DUF218 domain
HPEHFLOH_00008 2.2e-126
HPEHFLOH_00009 1.7e-148 yxeH S hydrolase
HPEHFLOH_00010 2.5e-261 ywfO S HD domain protein
HPEHFLOH_00011 4.8e-154 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HPEHFLOH_00012 3.8e-78 ywiB S Domain of unknown function (DUF1934)
HPEHFLOH_00013 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HPEHFLOH_00014 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPEHFLOH_00015 1.8e-245 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPEHFLOH_00016 3.1e-229 tdcC E amino acid
HPEHFLOH_00017 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HPEHFLOH_00018 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HPEHFLOH_00019 2.9e-131 S YheO-like PAS domain
HPEHFLOH_00020 5.1e-27
HPEHFLOH_00021 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPEHFLOH_00022 3e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPEHFLOH_00023 7.8e-41 rpmE2 J Ribosomal protein L31
HPEHFLOH_00024 1.2e-213 J translation release factor activity
HPEHFLOH_00025 9.2e-127 srtA 3.4.22.70 M sortase family
HPEHFLOH_00026 1.7e-91 lemA S LemA family
HPEHFLOH_00027 2.1e-139 htpX O Belongs to the peptidase M48B family
HPEHFLOH_00028 2e-146
HPEHFLOH_00029 1.1e-259 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPEHFLOH_00030 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HPEHFLOH_00031 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPEHFLOH_00032 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPEHFLOH_00033 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
HPEHFLOH_00034 0.0 kup P Transport of potassium into the cell
HPEHFLOH_00035 8.5e-193 P ABC transporter, substratebinding protein
HPEHFLOH_00036 8.3e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
HPEHFLOH_00037 5e-134 P ATPases associated with a variety of cellular activities
HPEHFLOH_00038 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HPEHFLOH_00039 2.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HPEHFLOH_00040 1.2e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPEHFLOH_00041 3.4e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPEHFLOH_00042 8e-129 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HPEHFLOH_00043 6.7e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
HPEHFLOH_00044 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPEHFLOH_00045 4.1e-84 S QueT transporter
HPEHFLOH_00046 2.1e-114 S (CBS) domain
HPEHFLOH_00047 1.9e-264 S Putative peptidoglycan binding domain
HPEHFLOH_00048 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPEHFLOH_00049 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPEHFLOH_00050 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPEHFLOH_00051 1.4e-287 yabM S Polysaccharide biosynthesis protein
HPEHFLOH_00052 2.2e-42 yabO J S4 domain protein
HPEHFLOH_00054 1.1e-63 divIC D Septum formation initiator
HPEHFLOH_00055 3.1e-74 yabR J RNA binding
HPEHFLOH_00056 1.1e-253 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPEHFLOH_00057 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HPEHFLOH_00058 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPEHFLOH_00059 3.8e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HPEHFLOH_00060 4.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPEHFLOH_00061 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HPEHFLOH_00067 5.1e-08
HPEHFLOH_00073 1.4e-90 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HPEHFLOH_00074 5.2e-182 P secondary active sulfate transmembrane transporter activity
HPEHFLOH_00075 3.4e-94
HPEHFLOH_00076 2e-94 K Acetyltransferase (GNAT) domain
HPEHFLOH_00077 1.1e-155 T Calcineurin-like phosphoesterase superfamily domain
HPEHFLOH_00079 1.2e-231 mntH P H( )-stimulated, divalent metal cation uptake system
HPEHFLOH_00080 9e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HPEHFLOH_00081 9.2e-256 mmuP E amino acid
HPEHFLOH_00082 1.2e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HPEHFLOH_00083 1.3e-290 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HPEHFLOH_00084 1.6e-121
HPEHFLOH_00085 3.5e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPEHFLOH_00086 1.4e-278 bmr3 EGP Major facilitator Superfamily
HPEHFLOH_00087 2.7e-129 N Cell shape-determining protein MreB
HPEHFLOH_00088 0.0 S Pfam Methyltransferase
HPEHFLOH_00089 3.2e-62 S Domain of unknown function (DUF4828)
HPEHFLOH_00090 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
HPEHFLOH_00091 7.1e-189 mocA S Oxidoreductase
HPEHFLOH_00092 1.5e-247 yfmL 3.6.4.13 L DEAD DEAH box helicase
HPEHFLOH_00094 7.5e-81 int L Belongs to the 'phage' integrase family
HPEHFLOH_00099 7.9e-11 tcdC
HPEHFLOH_00100 1.8e-29 E Zn peptidase
HPEHFLOH_00101 1.2e-28 ps115 K Helix-turn-helix XRE-family like proteins
HPEHFLOH_00103 8.4e-94 kilA K BRO family, N-terminal domain
HPEHFLOH_00105 7.4e-68 S DNA binding
HPEHFLOH_00111 3.3e-24 S Putative HNHc nuclease
HPEHFLOH_00112 3.6e-38 S Putative HNHc nuclease
HPEHFLOH_00114 1.6e-71 L DnaD domain protein
HPEHFLOH_00115 1.3e-145 pi346 L IstB-like ATP binding protein
HPEHFLOH_00117 4e-47
HPEHFLOH_00119 1.8e-14
HPEHFLOH_00121 2.7e-26 S YopX protein
HPEHFLOH_00122 3.9e-38
HPEHFLOH_00123 8.7e-15
HPEHFLOH_00125 2.5e-10 S YopX protein
HPEHFLOH_00126 1.7e-28
HPEHFLOH_00128 1.1e-74 S Transcriptional regulator, RinA family
HPEHFLOH_00130 3.1e-12 V HNH nucleases
HPEHFLOH_00131 5e-90 L HNH nucleases
HPEHFLOH_00133 1.6e-79 L Phage terminase, small subunit
HPEHFLOH_00134 0.0 S Phage Terminase
HPEHFLOH_00135 2.8e-25 S Protein of unknown function (DUF1056)
HPEHFLOH_00136 5.8e-222 S Phage portal protein
HPEHFLOH_00137 1.6e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HPEHFLOH_00138 1.2e-206 S peptidase activity
HPEHFLOH_00139 1.4e-51 S Phage gp6-like head-tail connector protein
HPEHFLOH_00140 1.1e-25 S Phage head-tail joining protein
HPEHFLOH_00141 1.7e-38
HPEHFLOH_00142 3.8e-26
HPEHFLOH_00143 2.3e-68 S Phage tail tube protein
HPEHFLOH_00146 0.0 S peptidoglycan catabolic process
HPEHFLOH_00147 5.7e-231 S Phage tail protein
HPEHFLOH_00148 0.0 S Phage minor structural protein
HPEHFLOH_00149 4e-183
HPEHFLOH_00152 1e-54
HPEHFLOH_00153 1.9e-161 M Glycosyl hydrolases family 25
HPEHFLOH_00154 4.8e-36 S Haemolysin XhlA
HPEHFLOH_00155 6.5e-34 hol S Bacteriophage holin
HPEHFLOH_00157 2.3e-75 T Universal stress protein family
HPEHFLOH_00158 6.1e-241 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEHFLOH_00159 6.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HPEHFLOH_00161 1.6e-73
HPEHFLOH_00162 2.1e-105
HPEHFLOH_00163 3.6e-131 L Helix-turn-helix domain
HPEHFLOH_00164 1.4e-158 L hmm pf00665
HPEHFLOH_00165 1.2e-252 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HPEHFLOH_00166 4.5e-211 pbpX1 V Beta-lactamase
HPEHFLOH_00167 2.5e-203 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HPEHFLOH_00168 1.9e-159 yihY S Belongs to the UPF0761 family
HPEHFLOH_00169 2.8e-131 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPEHFLOH_00170 6.8e-36 wcoI 2.7.10.1, 2.7.10.2 M biosynthesis protein
HPEHFLOH_00171 3.1e-27 D protein tyrosine kinase activity
HPEHFLOH_00172 2.9e-75 tagA 2.4.1.187 GT26 M Belongs to the glycosyltransferase 26 family
HPEHFLOH_00173 1.1e-86 GT4 M Glycosyltransferase Family 4
HPEHFLOH_00174 1.8e-60 GT4 M Glycosyl transferases group 1
HPEHFLOH_00175 4.1e-13 M -O-antigen
HPEHFLOH_00176 6.1e-269 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HPEHFLOH_00177 9.1e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HPEHFLOH_00178 4.2e-29
HPEHFLOH_00179 7.7e-94 ytqB 2.1.1.176 J Putative rRNA methylase
HPEHFLOH_00180 3.3e-123 3.6.1.27 I Acid phosphatase homologues
HPEHFLOH_00181 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPEHFLOH_00182 3e-301 ytgP S Polysaccharide biosynthesis protein
HPEHFLOH_00183 1.9e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPEHFLOH_00184 8.3e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPEHFLOH_00185 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
HPEHFLOH_00186 4.1e-84 uspA T Belongs to the universal stress protein A family
HPEHFLOH_00187 1.8e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HPEHFLOH_00188 3.4e-172 ugpA U Binding-protein-dependent transport system inner membrane component
HPEHFLOH_00189 1.1e-150 ugpE G ABC transporter permease
HPEHFLOH_00190 1.6e-260 ugpB G Bacterial extracellular solute-binding protein
HPEHFLOH_00191 5.4e-124 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HPEHFLOH_00192 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
HPEHFLOH_00193 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPEHFLOH_00194 8.7e-179 XK27_06930 V domain protein
HPEHFLOH_00196 2.5e-127 V Transport permease protein
HPEHFLOH_00197 2.3e-156 V ABC transporter
HPEHFLOH_00198 1.5e-175 K LytTr DNA-binding domain
HPEHFLOH_00199 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPEHFLOH_00200 1.6e-64 K helix_turn_helix, mercury resistance
HPEHFLOH_00201 3.5e-117 GM NAD(P)H-binding
HPEHFLOH_00202 7.9e-158 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HPEHFLOH_00203 7.6e-149 S Sucrose-6F-phosphate phosphohydrolase
HPEHFLOH_00204 1.7e-108
HPEHFLOH_00205 8.5e-224 pltK 2.7.13.3 T GHKL domain
HPEHFLOH_00206 1.6e-137 pltR K LytTr DNA-binding domain
HPEHFLOH_00207 1e-54
HPEHFLOH_00208 2.5e-59
HPEHFLOH_00209 3e-114 S CAAX protease self-immunity
HPEHFLOH_00210 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
HPEHFLOH_00211 2.5e-89
HPEHFLOH_00212 2.5e-46
HPEHFLOH_00213 0.0 uvrA2 L ABC transporter
HPEHFLOH_00216 5.9e-52
HPEHFLOH_00217 3.5e-10
HPEHFLOH_00218 2.1e-180
HPEHFLOH_00219 1.9e-89 gtcA S Teichoic acid glycosylation protein
HPEHFLOH_00220 3.6e-58 S Protein of unknown function (DUF1516)
HPEHFLOH_00221 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HPEHFLOH_00222 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HPEHFLOH_00223 6.8e-306 S Protein conserved in bacteria
HPEHFLOH_00224 9.7e-230 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HPEHFLOH_00225 2.5e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
HPEHFLOH_00226 1.8e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
HPEHFLOH_00227 2.1e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HPEHFLOH_00228 0.0 yfbS P Sodium:sulfate symporter transmembrane region
HPEHFLOH_00229 2.1e-244 dinF V MatE
HPEHFLOH_00230 1.9e-31
HPEHFLOH_00233 2.7e-79 elaA S Acetyltransferase (GNAT) domain
HPEHFLOH_00234 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HPEHFLOH_00235 2.7e-82
HPEHFLOH_00236 0.0 yhcA V MacB-like periplasmic core domain
HPEHFLOH_00237 7.6e-107
HPEHFLOH_00238 0.0 K PRD domain
HPEHFLOH_00239 2.4e-62 S Domain of unknown function (DUF3284)
HPEHFLOH_00240 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HPEHFLOH_00241 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HPEHFLOH_00242 6.1e-220 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEHFLOH_00243 1e-289 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPEHFLOH_00244 9.5e-209 EGP Major facilitator Superfamily
HPEHFLOH_00245 2e-114 M ErfK YbiS YcfS YnhG
HPEHFLOH_00246 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPEHFLOH_00247 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
HPEHFLOH_00248 1.4e-102 argO S LysE type translocator
HPEHFLOH_00249 2.7e-213 arcT 2.6.1.1 E Aminotransferase
HPEHFLOH_00250 4.4e-77 argR K Regulates arginine biosynthesis genes
HPEHFLOH_00251 2.9e-12
HPEHFLOH_00252 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HPEHFLOH_00253 1e-54 yheA S Belongs to the UPF0342 family
HPEHFLOH_00254 3.7e-232 yhaO L Ser Thr phosphatase family protein
HPEHFLOH_00255 0.0 L AAA domain
HPEHFLOH_00256 7.1e-186 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPEHFLOH_00257 3.1e-212
HPEHFLOH_00258 4.9e-179 3.4.21.102 M Peptidase family S41
HPEHFLOH_00259 1.2e-177 K LysR substrate binding domain
HPEHFLOH_00260 5.2e-110 1.3.5.4 S NADPH-dependent FMN reductase
HPEHFLOH_00261 0.0 1.3.5.4 C FAD binding domain
HPEHFLOH_00262 6.5e-99
HPEHFLOH_00263 1.8e-75 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HPEHFLOH_00264 3e-184 ykoT GT2 M Glycosyl transferase family 2
HPEHFLOH_00265 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPEHFLOH_00266 1.7e-19 S NUDIX domain
HPEHFLOH_00267 0.0 S membrane
HPEHFLOH_00268 6.4e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPEHFLOH_00269 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HPEHFLOH_00270 2.2e-221 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HPEHFLOH_00271 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPEHFLOH_00272 9.3e-106 GBS0088 S Nucleotidyltransferase
HPEHFLOH_00273 1.4e-106
HPEHFLOH_00274 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HPEHFLOH_00275 2.4e-46 K Bacterial regulatory proteins, tetR family
HPEHFLOH_00276 1.5e-50 K Bacterial regulatory proteins, tetR family
HPEHFLOH_00277 4.7e-241 npr 1.11.1.1 C NADH oxidase
HPEHFLOH_00278 0.0
HPEHFLOH_00279 1e-60
HPEHFLOH_00280 1.4e-192 S Fn3-like domain
HPEHFLOH_00281 5.2e-103 S WxL domain surface cell wall-binding
HPEHFLOH_00282 3.5e-78 S WxL domain surface cell wall-binding
HPEHFLOH_00283 2.1e-118 draG 3.2.2.24 O ADP-ribosylglycohydrolase
HPEHFLOH_00284 1.5e-137 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPEHFLOH_00285 2e-42
HPEHFLOH_00286 9.9e-82 hit FG histidine triad
HPEHFLOH_00287 8.1e-134 ecsA V ABC transporter, ATP-binding protein
HPEHFLOH_00288 2.1e-224 ecsB U ABC transporter
HPEHFLOH_00289 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HPEHFLOH_00290 2.6e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPEHFLOH_00291 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
HPEHFLOH_00292 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPEHFLOH_00293 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HPEHFLOH_00294 1.5e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HPEHFLOH_00295 7.9e-21 S Virus attachment protein p12 family
HPEHFLOH_00296 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HPEHFLOH_00297 1.3e-34 feoA P FeoA domain
HPEHFLOH_00298 4.2e-144 sufC O FeS assembly ATPase SufC
HPEHFLOH_00299 2.6e-244 sufD O FeS assembly protein SufD
HPEHFLOH_00300 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPEHFLOH_00301 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
HPEHFLOH_00302 1.4e-272 sufB O assembly protein SufB
HPEHFLOH_00303 3.2e-179 fecB P Periplasmic binding protein
HPEHFLOH_00304 1.3e-137 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HPEHFLOH_00305 6.4e-166 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPEHFLOH_00306 2.2e-81 fld C NrdI Flavodoxin like
HPEHFLOH_00307 4.5e-70 moaE 2.8.1.12 H MoaE protein
HPEHFLOH_00308 5.4e-34 moaD 2.8.1.12 H ThiS family
HPEHFLOH_00309 4.5e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HPEHFLOH_00310 2.5e-217 narK P Transporter, major facilitator family protein
HPEHFLOH_00311 8.8e-59 yitW S Iron-sulfur cluster assembly protein
HPEHFLOH_00312 8.1e-157 hipB K Helix-turn-helix
HPEHFLOH_00313 3.9e-162 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HPEHFLOH_00314 1.5e-183
HPEHFLOH_00315 7.5e-49
HPEHFLOH_00316 6.1e-117 nreC K PFAM regulatory protein LuxR
HPEHFLOH_00317 8.6e-190 comP 2.7.13.3 F Sensor histidine kinase
HPEHFLOH_00318 3.9e-75 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
HPEHFLOH_00319 7.8e-39
HPEHFLOH_00320 2.5e-99 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HPEHFLOH_00321 7.2e-86 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HPEHFLOH_00322 1.8e-89 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HPEHFLOH_00323 4.1e-231 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HPEHFLOH_00324 1.6e-82 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HPEHFLOH_00325 3.2e-192 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HPEHFLOH_00326 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HPEHFLOH_00327 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HPEHFLOH_00328 7.3e-98 narJ C Nitrate reductase delta subunit
HPEHFLOH_00329 2.7e-123 narI 1.7.5.1 C Nitrate reductase
HPEHFLOH_00330 3.3e-175
HPEHFLOH_00331 1.5e-73
HPEHFLOH_00332 2.3e-96 S Protein of unknown function (DUF2975)
HPEHFLOH_00333 1.7e-28 yozG K Transcriptional regulator
HPEHFLOH_00334 4.5e-121 ybhL S Belongs to the BI1 family
HPEHFLOH_00335 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPEHFLOH_00336 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HPEHFLOH_00337 2.7e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPEHFLOH_00338 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPEHFLOH_00339 1.1e-248 dnaB L replication initiation and membrane attachment
HPEHFLOH_00340 3.3e-172 dnaI L Primosomal protein DnaI
HPEHFLOH_00341 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPEHFLOH_00342 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPEHFLOH_00343 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HPEHFLOH_00344 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPEHFLOH_00345 8.8e-39
HPEHFLOH_00346 1.4e-239 yrvN L AAA C-terminal domain
HPEHFLOH_00347 6.1e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HPEHFLOH_00348 1e-62 hxlR K Transcriptional regulator, HxlR family
HPEHFLOH_00349 1.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HPEHFLOH_00350 1.4e-250 pgaC GT2 M Glycosyl transferase
HPEHFLOH_00351 1.4e-98 yqeG S HAD phosphatase, family IIIA
HPEHFLOH_00352 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
HPEHFLOH_00353 1.1e-50 yhbY J RNA-binding protein
HPEHFLOH_00354 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPEHFLOH_00355 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HPEHFLOH_00356 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPEHFLOH_00357 4.4e-140 yqeM Q Methyltransferase
HPEHFLOH_00358 2.2e-218 ylbM S Belongs to the UPF0348 family
HPEHFLOH_00359 6e-97 yceD S Uncharacterized ACR, COG1399
HPEHFLOH_00360 2.2e-89 S Peptidase propeptide and YPEB domain
HPEHFLOH_00361 2e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPEHFLOH_00362 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPEHFLOH_00363 4.2e-245 rarA L recombination factor protein RarA
HPEHFLOH_00364 4.3e-121 K response regulator
HPEHFLOH_00365 1.5e-305 arlS 2.7.13.3 T Histidine kinase
HPEHFLOH_00366 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HPEHFLOH_00367 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HPEHFLOH_00368 4.5e-227 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HPEHFLOH_00369 8.4e-94 S SdpI/YhfL protein family
HPEHFLOH_00370 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPEHFLOH_00371 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HPEHFLOH_00372 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPEHFLOH_00373 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPEHFLOH_00374 7.4e-64 yodB K Transcriptional regulator, HxlR family
HPEHFLOH_00375 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPEHFLOH_00376 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HPEHFLOH_00377 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPEHFLOH_00378 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
HPEHFLOH_00379 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPEHFLOH_00380 3.6e-94 liaI S membrane
HPEHFLOH_00381 3.4e-74 XK27_02470 K LytTr DNA-binding domain
HPEHFLOH_00382 1.5e-54 yneR S Belongs to the HesB IscA family
HPEHFLOH_00383 0.0 S membrane
HPEHFLOH_00384 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HPEHFLOH_00385 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HPEHFLOH_00386 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HPEHFLOH_00387 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
HPEHFLOH_00388 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HPEHFLOH_00389 5.7e-180 glk 2.7.1.2 G Glucokinase
HPEHFLOH_00390 1.9e-110 pepE 3.4.13.21 E Belongs to the peptidase S51 family
HPEHFLOH_00391 4.4e-68 yqhL P Rhodanese-like protein
HPEHFLOH_00392 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
HPEHFLOH_00393 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
HPEHFLOH_00394 2.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPEHFLOH_00395 4.6e-64 glnR K Transcriptional regulator
HPEHFLOH_00396 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
HPEHFLOH_00397 1.3e-160
HPEHFLOH_00398 1.2e-180
HPEHFLOH_00399 2.4e-98 dut S Protein conserved in bacteria
HPEHFLOH_00400 5.3e-56
HPEHFLOH_00401 1.7e-30
HPEHFLOH_00404 5.4e-19
HPEHFLOH_00405 1.8e-89 K Transcriptional regulator
HPEHFLOH_00406 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HPEHFLOH_00407 3.2e-53 ysxB J Cysteine protease Prp
HPEHFLOH_00408 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HPEHFLOH_00409 5.9e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HPEHFLOH_00410 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPEHFLOH_00411 3.5e-74 yqhY S Asp23 family, cell envelope-related function
HPEHFLOH_00412 1.5e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPEHFLOH_00413 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPEHFLOH_00414 1.1e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPEHFLOH_00415 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPEHFLOH_00416 6.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPEHFLOH_00417 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HPEHFLOH_00418 7.4e-77 argR K Regulates arginine biosynthesis genes
HPEHFLOH_00419 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
HPEHFLOH_00420 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
HPEHFLOH_00421 1.2e-104 opuCB E ABC transporter permease
HPEHFLOH_00422 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HPEHFLOH_00423 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
HPEHFLOH_00424 4.5e-55
HPEHFLOH_00425 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HPEHFLOH_00426 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPEHFLOH_00427 1.2e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPEHFLOH_00428 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPEHFLOH_00429 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPEHFLOH_00430 2.1e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HPEHFLOH_00431 1.7e-134 stp 3.1.3.16 T phosphatase
HPEHFLOH_00432 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HPEHFLOH_00433 3e-162 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPEHFLOH_00434 8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HPEHFLOH_00435 1.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HPEHFLOH_00436 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HPEHFLOH_00437 1.8e-57 asp S Asp23 family, cell envelope-related function
HPEHFLOH_00438 0.0 yloV S DAK2 domain fusion protein YloV
HPEHFLOH_00439 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPEHFLOH_00440 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HPEHFLOH_00441 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPEHFLOH_00442 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPEHFLOH_00443 0.0 smc D Required for chromosome condensation and partitioning
HPEHFLOH_00444 6.6e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPEHFLOH_00445 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HPEHFLOH_00446 2.9e-220 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPEHFLOH_00447 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HPEHFLOH_00448 2.6e-39 ylqC S Belongs to the UPF0109 family
HPEHFLOH_00449 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPEHFLOH_00450 2.2e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HPEHFLOH_00451 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPEHFLOH_00452 1.4e-50
HPEHFLOH_00453 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HPEHFLOH_00454 5.3e-86
HPEHFLOH_00455 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HPEHFLOH_00456 4.5e-270 XK27_00765
HPEHFLOH_00458 1.9e-267 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
HPEHFLOH_00459 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
HPEHFLOH_00460 2.7e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPEHFLOH_00461 2.9e-121 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HPEHFLOH_00462 1.6e-109 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HPEHFLOH_00463 2.3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPEHFLOH_00464 8.7e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPEHFLOH_00465 1.7e-96 entB 3.5.1.19 Q Isochorismatase family
HPEHFLOH_00466 2.6e-177 1.6.5.5 C Zinc-binding dehydrogenase
HPEHFLOH_00467 1.7e-66 ybbJ K Acetyltransferase (GNAT) family
HPEHFLOH_00468 5.8e-141 E glutamate:sodium symporter activity
HPEHFLOH_00469 5.4e-66 E glutamate:sodium symporter activity
HPEHFLOH_00470 2.6e-101 3.5.1.47 E Peptidase family M20/M25/M40
HPEHFLOH_00471 5.3e-101 3.5.1.47 E Peptidase family M20/M25/M40
HPEHFLOH_00472 2.7e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HPEHFLOH_00473 1.2e-58 S Protein of unknown function (DUF1648)
HPEHFLOH_00475 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPEHFLOH_00476 1.1e-178 yneE K Transcriptional regulator
HPEHFLOH_00477 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HPEHFLOH_00478 5e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPEHFLOH_00479 1.3e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HPEHFLOH_00480 4.4e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HPEHFLOH_00481 2.1e-126 IQ reductase
HPEHFLOH_00482 9.5e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HPEHFLOH_00483 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPEHFLOH_00484 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HPEHFLOH_00485 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HPEHFLOH_00486 3.5e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPEHFLOH_00487 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HPEHFLOH_00488 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HPEHFLOH_00489 1.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HPEHFLOH_00490 4.1e-122 S Protein of unknown function (DUF554)
HPEHFLOH_00491 1.6e-160 K LysR substrate binding domain
HPEHFLOH_00492 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
HPEHFLOH_00493 4.2e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPEHFLOH_00494 2.3e-93 K transcriptional regulator
HPEHFLOH_00495 7.5e-300 norB EGP Major Facilitator
HPEHFLOH_00496 1.2e-139 f42a O Band 7 protein
HPEHFLOH_00497 4.2e-53
HPEHFLOH_00498 1.3e-28
HPEHFLOH_00499 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HPEHFLOH_00500 1.8e-80 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
HPEHFLOH_00501 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HPEHFLOH_00502 7.9e-41
HPEHFLOH_00503 1.9e-67 tspO T TspO/MBR family
HPEHFLOH_00504 6.3e-76 uspA T Belongs to the universal stress protein A family
HPEHFLOH_00505 8e-66 S Protein of unknown function (DUF805)
HPEHFLOH_00506 3.2e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HPEHFLOH_00507 1.3e-35
HPEHFLOH_00508 3.1e-14
HPEHFLOH_00509 2.5e-40 S transglycosylase associated protein
HPEHFLOH_00510 4.8e-29 S CsbD-like
HPEHFLOH_00511 9.4e-40
HPEHFLOH_00512 8.6e-281 pipD E Dipeptidase
HPEHFLOH_00513 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HPEHFLOH_00514 1.8e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPEHFLOH_00515 3e-170 2.5.1.74 H UbiA prenyltransferase family
HPEHFLOH_00516 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
HPEHFLOH_00517 6.3e-45
HPEHFLOH_00518 1.7e-44
HPEHFLOH_00519 1.1e-258 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HPEHFLOH_00520 4.8e-266 yfnA E Amino Acid
HPEHFLOH_00521 1.2e-149 yitU 3.1.3.104 S hydrolase
HPEHFLOH_00522 5.5e-269 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HPEHFLOH_00523 6.1e-88 S Domain of unknown function (DUF4767)
HPEHFLOH_00525 2.5e-250 malT G Major Facilitator
HPEHFLOH_00526 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HPEHFLOH_00527 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HPEHFLOH_00528 6.2e-196 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HPEHFLOH_00529 5e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HPEHFLOH_00530 2.4e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HPEHFLOH_00531 3.4e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HPEHFLOH_00532 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HPEHFLOH_00533 2.1e-72 ypmB S protein conserved in bacteria
HPEHFLOH_00534 4.3e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HPEHFLOH_00535 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HPEHFLOH_00536 1.3e-128 dnaD L Replication initiation and membrane attachment
HPEHFLOH_00538 3.9e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPEHFLOH_00539 2e-99 metI P ABC transporter permease
HPEHFLOH_00540 2.1e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HPEHFLOH_00541 4.4e-83 uspA T Universal stress protein family
HPEHFLOH_00542 1.4e-301 ftpA P Binding-protein-dependent transport system inner membrane component
HPEHFLOH_00543 1.7e-182 ftpB P Bacterial extracellular solute-binding protein
HPEHFLOH_00544 1.8e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
HPEHFLOH_00545 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HPEHFLOH_00546 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HPEHFLOH_00547 2.4e-109 ypsA S Belongs to the UPF0398 family
HPEHFLOH_00548 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HPEHFLOH_00550 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HPEHFLOH_00551 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPEHFLOH_00552 1.8e-243 P Major Facilitator Superfamily
HPEHFLOH_00553 4e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HPEHFLOH_00554 1.7e-72 S SnoaL-like domain
HPEHFLOH_00555 2.8e-241 M Glycosyltransferase, group 2 family protein
HPEHFLOH_00556 4.3e-208 mccF V LD-carboxypeptidase
HPEHFLOH_00557 1.4e-78 K Acetyltransferase (GNAT) domain
HPEHFLOH_00558 2.6e-239 M hydrolase, family 25
HPEHFLOH_00559 2.3e-181 mccF 3.4.17.13 V LD-carboxypeptidase
HPEHFLOH_00560 1.3e-123
HPEHFLOH_00561 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
HPEHFLOH_00562 2.3e-193
HPEHFLOH_00563 1.5e-146 S hydrolase activity, acting on ester bonds
HPEHFLOH_00564 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
HPEHFLOH_00565 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
HPEHFLOH_00566 2.2e-61 esbA S Family of unknown function (DUF5322)
HPEHFLOH_00567 2.3e-293 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HPEHFLOH_00568 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPEHFLOH_00569 3.5e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPEHFLOH_00570 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPEHFLOH_00571 2.8e-207 carA 6.3.5.5 F Belongs to the CarA family
HPEHFLOH_00572 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HPEHFLOH_00573 6.4e-113 pgm5 G Phosphoglycerate mutase family
HPEHFLOH_00574 2.8e-38 frataxin S Domain of unknown function (DU1801)
HPEHFLOH_00578 1.1e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HPEHFLOH_00579 3.5e-69 S LuxR family transcriptional regulator
HPEHFLOH_00580 8.6e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
HPEHFLOH_00582 4.8e-90 3.6.1.55 F NUDIX domain
HPEHFLOH_00583 1.6e-163 V ABC transporter, ATP-binding protein
HPEHFLOH_00584 1.3e-131 S ABC-2 family transporter protein
HPEHFLOH_00585 0.0 FbpA K Fibronectin-binding protein
HPEHFLOH_00586 1.9e-66 K Transcriptional regulator
HPEHFLOH_00587 7e-161 degV S EDD domain protein, DegV family
HPEHFLOH_00588 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HPEHFLOH_00589 7.6e-132 S Protein of unknown function (DUF975)
HPEHFLOH_00590 1.7e-09
HPEHFLOH_00591 2.4e-49
HPEHFLOH_00592 4.8e-148 2.7.7.12 C Domain of unknown function (DUF4931)
HPEHFLOH_00593 1.6e-211 pmrB EGP Major facilitator Superfamily
HPEHFLOH_00594 4.6e-12
HPEHFLOH_00595 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HPEHFLOH_00596 4.6e-129 yejC S Protein of unknown function (DUF1003)
HPEHFLOH_00597 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
HPEHFLOH_00598 1.1e-245 cycA E Amino acid permease
HPEHFLOH_00599 1.6e-120
HPEHFLOH_00600 4.1e-59
HPEHFLOH_00601 1.1e-279 lldP C L-lactate permease
HPEHFLOH_00602 1.4e-227
HPEHFLOH_00603 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HPEHFLOH_00604 2.8e-193 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HPEHFLOH_00605 6.8e-217 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPEHFLOH_00606 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPEHFLOH_00607 1.2e-94 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HPEHFLOH_00608 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
HPEHFLOH_00609 6e-252 gshR1 1.8.1.7 C Glutathione reductase
HPEHFLOH_00610 1.8e-66
HPEHFLOH_00611 6.3e-246 M Glycosyl transferase family group 2
HPEHFLOH_00612 5.7e-275 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPEHFLOH_00613 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain
HPEHFLOH_00614 4.2e-32 S YozE SAM-like fold
HPEHFLOH_00615 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPEHFLOH_00616 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HPEHFLOH_00617 2.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
HPEHFLOH_00618 1.2e-177 K Transcriptional regulator
HPEHFLOH_00619 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPEHFLOH_00620 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HPEHFLOH_00621 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HPEHFLOH_00622 1.4e-169 lacX 5.1.3.3 G Aldose 1-epimerase
HPEHFLOH_00623 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HPEHFLOH_00624 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HPEHFLOH_00625 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HPEHFLOH_00626 2.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HPEHFLOH_00627 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPEHFLOH_00628 3.3e-158 dprA LU DNA protecting protein DprA
HPEHFLOH_00629 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPEHFLOH_00630 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HPEHFLOH_00632 5.2e-228 XK27_05470 E Methionine synthase
HPEHFLOH_00633 8.9e-170 cpsY K Transcriptional regulator, LysR family
HPEHFLOH_00634 1.9e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HPEHFLOH_00635 7.9e-199 XK27_00915 C Luciferase-like monooxygenase
HPEHFLOH_00636 9.5e-251 emrY EGP Major facilitator Superfamily
HPEHFLOH_00637 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HPEHFLOH_00638 3.4e-35 yozE S Belongs to the UPF0346 family
HPEHFLOH_00639 7.7e-112 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HPEHFLOH_00640 1.4e-146 ypmR E GDSL-like Lipase/Acylhydrolase
HPEHFLOH_00641 5.1e-148 DegV S EDD domain protein, DegV family
HPEHFLOH_00642 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPEHFLOH_00643 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPEHFLOH_00644 0.0 yfmR S ABC transporter, ATP-binding protein
HPEHFLOH_00645 9.6e-85
HPEHFLOH_00646 4.7e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPEHFLOH_00647 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HPEHFLOH_00648 2e-149 3.1.3.102, 3.1.3.104 S hydrolase
HPEHFLOH_00649 5.4e-218 S Tetratricopeptide repeat protein
HPEHFLOH_00650 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPEHFLOH_00651 1.8e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HPEHFLOH_00652 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
HPEHFLOH_00653 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HPEHFLOH_00654 4.4e-19 M Lysin motif
HPEHFLOH_00655 2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HPEHFLOH_00656 3.8e-193 ypbB 5.1.3.1 S Helix-turn-helix domain
HPEHFLOH_00657 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPEHFLOH_00658 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPEHFLOH_00659 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HPEHFLOH_00660 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HPEHFLOH_00661 6.2e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HPEHFLOH_00662 1.1e-164 xerD D recombinase XerD
HPEHFLOH_00663 2.9e-170 cvfB S S1 domain
HPEHFLOH_00664 1.5e-74 yeaL S Protein of unknown function (DUF441)
HPEHFLOH_00665 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HPEHFLOH_00666 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HPEHFLOH_00667 0.0 dnaE 2.7.7.7 L DNA polymerase
HPEHFLOH_00668 7.3e-29 S Protein of unknown function (DUF2929)
HPEHFLOH_00669 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPEHFLOH_00670 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HPEHFLOH_00671 2.7e-196 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPEHFLOH_00672 5.1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
HPEHFLOH_00673 8.4e-221 M O-Antigen ligase
HPEHFLOH_00674 9.1e-120 drrB U ABC-2 type transporter
HPEHFLOH_00675 2.3e-165 drrA V ABC transporter
HPEHFLOH_00676 1.5e-83 K helix_turn_helix multiple antibiotic resistance protein
HPEHFLOH_00677 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HPEHFLOH_00678 7.8e-61 P Rhodanese Homology Domain
HPEHFLOH_00679 2.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
HPEHFLOH_00680 6.6e-207
HPEHFLOH_00681 3.4e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
HPEHFLOH_00682 3.4e-180 C Zinc-binding dehydrogenase
HPEHFLOH_00683 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
HPEHFLOH_00684 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPEHFLOH_00685 8.5e-241 EGP Major facilitator Superfamily
HPEHFLOH_00686 4.3e-77 K Transcriptional regulator
HPEHFLOH_00687 2.8e-210 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HPEHFLOH_00688 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPEHFLOH_00689 1e-136 K DeoR C terminal sensor domain
HPEHFLOH_00690 6.3e-108 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HPEHFLOH_00691 9.1e-71 yneH 1.20.4.1 P ArsC family
HPEHFLOH_00692 1.4e-68 S Protein of unknown function (DUF1722)
HPEHFLOH_00693 7.5e-112 GM epimerase
HPEHFLOH_00694 0.0 CP_1020 S Zinc finger, swim domain protein
HPEHFLOH_00695 5e-122 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
HPEHFLOH_00696 1.6e-79 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HPEHFLOH_00697 1.3e-128 K Helix-turn-helix domain, rpiR family
HPEHFLOH_00698 7.7e-160 S Alpha beta hydrolase
HPEHFLOH_00699 9.9e-112 GM NmrA-like family
HPEHFLOH_00700 4.9e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
HPEHFLOH_00701 1.9e-161 K Transcriptional regulator
HPEHFLOH_00702 1.1e-170 C nadph quinone reductase
HPEHFLOH_00703 3.1e-13 S Alpha beta hydrolase
HPEHFLOH_00704 2.1e-271 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPEHFLOH_00705 4e-102 desR K helix_turn_helix, Lux Regulon
HPEHFLOH_00706 5.2e-201 desK 2.7.13.3 T Histidine kinase
HPEHFLOH_00707 1.1e-133 yvfS V ABC-2 type transporter
HPEHFLOH_00708 2.6e-158 yvfR V ABC transporter
HPEHFLOH_00710 6e-82 K Acetyltransferase (GNAT) domain
HPEHFLOH_00711 2.6e-77 K MarR family
HPEHFLOH_00712 6.5e-114 S Psort location CytoplasmicMembrane, score
HPEHFLOH_00713 5.8e-12 yjdF S Protein of unknown function (DUF2992)
HPEHFLOH_00714 1.5e-161 V ABC transporter, ATP-binding protein
HPEHFLOH_00715 2.2e-126 S ABC-2 family transporter protein
HPEHFLOH_00716 3e-198
HPEHFLOH_00717 2e-202
HPEHFLOH_00718 7e-164 ytrB V ABC transporter, ATP-binding protein
HPEHFLOH_00719 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
HPEHFLOH_00720 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPEHFLOH_00721 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPEHFLOH_00722 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HPEHFLOH_00723 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HPEHFLOH_00724 1.2e-146 recO L Involved in DNA repair and RecF pathway recombination
HPEHFLOH_00725 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPEHFLOH_00726 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HPEHFLOH_00727 1.6e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPEHFLOH_00728 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
HPEHFLOH_00729 1.7e-70 yqeY S YqeY-like protein
HPEHFLOH_00730 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HPEHFLOH_00731 4.8e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HPEHFLOH_00732 5e-128 C Enoyl-(Acyl carrier protein) reductase
HPEHFLOH_00733 4.5e-171 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HPEHFLOH_00734 2.5e-222 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPEHFLOH_00735 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HPEHFLOH_00736 4.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPEHFLOH_00737 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HPEHFLOH_00738 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HPEHFLOH_00739 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HPEHFLOH_00740 1.5e-163 yniA G Fructosamine kinase
HPEHFLOH_00741 2.2e-116 3.1.3.18 J HAD-hyrolase-like
HPEHFLOH_00742 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPEHFLOH_00743 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPEHFLOH_00744 1.4e-56
HPEHFLOH_00745 5.4e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPEHFLOH_00746 1e-176 prmA J Ribosomal protein L11 methyltransferase
HPEHFLOH_00747 2.4e-65 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HPEHFLOH_00748 2e-36 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HPEHFLOH_00749 1.4e-49
HPEHFLOH_00750 5.4e-49
HPEHFLOH_00751 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPEHFLOH_00752 2.3e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HPEHFLOH_00753 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPEHFLOH_00754 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HPEHFLOH_00755 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HPEHFLOH_00756 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
HPEHFLOH_00757 3.7e-173 pbpX2 V Beta-lactamase
HPEHFLOH_00758 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPEHFLOH_00759 0.0 dnaK O Heat shock 70 kDa protein
HPEHFLOH_00760 1.6e-79 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPEHFLOH_00761 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPEHFLOH_00762 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HPEHFLOH_00763 1.6e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HPEHFLOH_00764 2.1e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPEHFLOH_00765 2.1e-55 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPEHFLOH_00766 6.5e-196 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HPEHFLOH_00767 1.4e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPEHFLOH_00768 2.9e-93
HPEHFLOH_00769 5.1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPEHFLOH_00770 2.5e-264 ydiN 5.4.99.5 G Major Facilitator
HPEHFLOH_00771 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPEHFLOH_00772 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPEHFLOH_00773 1.1e-47 ylxQ J ribosomal protein
HPEHFLOH_00774 9.5e-49 ylxR K Protein of unknown function (DUF448)
HPEHFLOH_00775 1.1e-217 nusA K Participates in both transcription termination and antitermination
HPEHFLOH_00776 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
HPEHFLOH_00777 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPEHFLOH_00778 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPEHFLOH_00779 6.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HPEHFLOH_00780 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HPEHFLOH_00781 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPEHFLOH_00782 5.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPEHFLOH_00783 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HPEHFLOH_00784 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPEHFLOH_00785 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HPEHFLOH_00786 4.7e-134 S Haloacid dehalogenase-like hydrolase
HPEHFLOH_00787 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPEHFLOH_00788 1.8e-39 yazA L GIY-YIG catalytic domain protein
HPEHFLOH_00789 9.3e-133 yabB 2.1.1.223 L Methyltransferase small domain
HPEHFLOH_00790 1.2e-117 plsC 2.3.1.51 I Acyltransferase
HPEHFLOH_00791 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
HPEHFLOH_00792 2.9e-36 ynzC S UPF0291 protein
HPEHFLOH_00793 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPEHFLOH_00794 3.7e-87
HPEHFLOH_00795 3.9e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HPEHFLOH_00796 2e-75
HPEHFLOH_00797 3.3e-65
HPEHFLOH_00798 1.5e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
HPEHFLOH_00799 9.2e-101 L Helix-turn-helix domain
HPEHFLOH_00800 2.1e-221 lytR5 K Cell envelope-related transcriptional attenuator domain
HPEHFLOH_00801 3.7e-31 P ATPases associated with a variety of cellular activities
HPEHFLOH_00802 6.9e-99 P ATPases associated with a variety of cellular activities
HPEHFLOH_00803 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
HPEHFLOH_00804 1e-229 rodA D Cell cycle protein
HPEHFLOH_00806 1.6e-31
HPEHFLOH_00807 1.1e-138 Q Methyltransferase
HPEHFLOH_00808 8.5e-57 ybjQ S Belongs to the UPF0145 family
HPEHFLOH_00809 6.1e-211 EGP Major facilitator Superfamily
HPEHFLOH_00810 6.6e-99 K Helix-turn-helix domain
HPEHFLOH_00811 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPEHFLOH_00812 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HPEHFLOH_00813 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
HPEHFLOH_00814 8.2e-140 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPEHFLOH_00815 8.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HPEHFLOH_00816 3.2e-46
HPEHFLOH_00817 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPEHFLOH_00818 1.5e-135 fruR K DeoR C terminal sensor domain
HPEHFLOH_00819 2.3e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HPEHFLOH_00820 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HPEHFLOH_00821 4.2e-72 cpdA S Calcineurin-like phosphoesterase
HPEHFLOH_00822 3.6e-137 cpdA S Calcineurin-like phosphoesterase
HPEHFLOH_00823 1.3e-260 cps4J S Polysaccharide biosynthesis protein
HPEHFLOH_00824 2.3e-176 cps4I M Glycosyltransferase like family 2
HPEHFLOH_00825 1.1e-231
HPEHFLOH_00826 2.9e-190 cps4G M Glycosyltransferase Family 4
HPEHFLOH_00827 6.1e-202 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
HPEHFLOH_00828 1.8e-127 tuaA M Bacterial sugar transferase
HPEHFLOH_00829 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
HPEHFLOH_00830 1e-145 ywqE 3.1.3.48 GM PHP domain protein
HPEHFLOH_00831 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HPEHFLOH_00832 2.9e-126 epsB M biosynthesis protein
HPEHFLOH_00833 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPEHFLOH_00834 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPEHFLOH_00835 9.2e-270 glnPH2 P ABC transporter permease
HPEHFLOH_00836 4.3e-22
HPEHFLOH_00837 9.9e-73 S Iron-sulphur cluster biosynthesis
HPEHFLOH_00838 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HPEHFLOH_00839 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HPEHFLOH_00840 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPEHFLOH_00841 7.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPEHFLOH_00842 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPEHFLOH_00843 1e-157 S Tetratricopeptide repeat
HPEHFLOH_00844 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPEHFLOH_00845 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPEHFLOH_00846 2e-190 mdtG EGP Major Facilitator Superfamily
HPEHFLOH_00847 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPEHFLOH_00848 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HPEHFLOH_00849 2.4e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
HPEHFLOH_00850 0.0 comEC S Competence protein ComEC
HPEHFLOH_00851 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
HPEHFLOH_00852 6.8e-125 comEA L Competence protein ComEA
HPEHFLOH_00853 9.6e-197 ylbL T Belongs to the peptidase S16 family
HPEHFLOH_00854 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPEHFLOH_00855 2.2e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HPEHFLOH_00856 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HPEHFLOH_00857 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HPEHFLOH_00858 1.6e-205 ftsW D Belongs to the SEDS family
HPEHFLOH_00859 1.9e-273
HPEHFLOH_00860 0.0 typA T GTP-binding protein TypA
HPEHFLOH_00861 1.4e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HPEHFLOH_00862 3.3e-46 yktA S Belongs to the UPF0223 family
HPEHFLOH_00863 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
HPEHFLOH_00864 3.5e-266 lpdA 1.8.1.4 C Dehydrogenase
HPEHFLOH_00865 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HPEHFLOH_00866 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HPEHFLOH_00867 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HPEHFLOH_00868 9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPEHFLOH_00869 1.6e-85
HPEHFLOH_00870 3.1e-33 ykzG S Belongs to the UPF0356 family
HPEHFLOH_00871 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPEHFLOH_00872 5.7e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HPEHFLOH_00873 1.7e-28
HPEHFLOH_00874 4.1e-108 mltD CBM50 M NlpC P60 family protein
HPEHFLOH_00875 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPEHFLOH_00876 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HPEHFLOH_00877 1.6e-120 S Repeat protein
HPEHFLOH_00878 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HPEHFLOH_00879 5.5e-267 N domain, Protein
HPEHFLOH_00880 1.7e-193 S Bacterial protein of unknown function (DUF916)
HPEHFLOH_00881 3.9e-120 N WxL domain surface cell wall-binding
HPEHFLOH_00882 2.6e-115 ktrA P domain protein
HPEHFLOH_00883 1.3e-241 ktrB P Potassium uptake protein
HPEHFLOH_00884 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPEHFLOH_00885 4.9e-57 XK27_04120 S Putative amino acid metabolism
HPEHFLOH_00886 1.6e-216 iscS 2.8.1.7 E Aminotransferase class V
HPEHFLOH_00887 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPEHFLOH_00888 4.6e-28
HPEHFLOH_00889 5.6e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HPEHFLOH_00890 4.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HPEHFLOH_00891 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPEHFLOH_00892 1.2e-86 divIVA D DivIVA domain protein
HPEHFLOH_00893 3.4e-146 ylmH S S4 domain protein
HPEHFLOH_00894 1.2e-36 yggT S YGGT family
HPEHFLOH_00895 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPEHFLOH_00896 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPEHFLOH_00897 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPEHFLOH_00898 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HPEHFLOH_00899 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPEHFLOH_00900 3.6e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPEHFLOH_00901 2.4e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPEHFLOH_00902 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HPEHFLOH_00903 1.1e-52 ftsL D Cell division protein FtsL
HPEHFLOH_00904 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPEHFLOH_00905 1.9e-77 mraZ K Belongs to the MraZ family
HPEHFLOH_00906 1.9e-62 S Protein of unknown function (DUF3397)
HPEHFLOH_00907 4.2e-175 corA P CorA-like Mg2+ transporter protein
HPEHFLOH_00908 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HPEHFLOH_00909 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPEHFLOH_00910 1.8e-113 ywnB S NAD(P)H-binding
HPEHFLOH_00911 9.8e-210 brnQ U Component of the transport system for branched-chain amino acids
HPEHFLOH_00913 1.8e-161 rrmA 2.1.1.187 H Methyltransferase
HPEHFLOH_00914 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPEHFLOH_00915 4.3e-206 XK27_05220 S AI-2E family transporter
HPEHFLOH_00916 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HPEHFLOH_00917 7.4e-194 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HPEHFLOH_00918 5.1e-116 cutC P Participates in the control of copper homeostasis
HPEHFLOH_00919 4.4e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HPEHFLOH_00920 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPEHFLOH_00921 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
HPEHFLOH_00922 3.6e-114 yjbH Q Thioredoxin
HPEHFLOH_00923 0.0 pepF E oligoendopeptidase F
HPEHFLOH_00924 5.8e-205 coiA 3.6.4.12 S Competence protein
HPEHFLOH_00925 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HPEHFLOH_00926 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HPEHFLOH_00927 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
HPEHFLOH_00928 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HPEHFLOH_00938 5.5e-08
HPEHFLOH_00948 1.5e-62
HPEHFLOH_00949 1.6e-75 yugI 5.3.1.9 J general stress protein
HPEHFLOH_00950 2.7e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPEHFLOH_00951 3e-119 dedA S SNARE-like domain protein
HPEHFLOH_00952 3.9e-116 S Protein of unknown function (DUF1461)
HPEHFLOH_00953 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HPEHFLOH_00954 1.5e-80 yutD S Protein of unknown function (DUF1027)
HPEHFLOH_00955 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HPEHFLOH_00956 4.4e-117 S Calcineurin-like phosphoesterase
HPEHFLOH_00957 1.2e-252 cycA E Amino acid permease
HPEHFLOH_00958 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPEHFLOH_00959 1.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HPEHFLOH_00961 4.5e-88 S Prokaryotic N-terminal methylation motif
HPEHFLOH_00962 8.6e-20
HPEHFLOH_00963 3.2e-83 gspG NU general secretion pathway protein
HPEHFLOH_00964 5.5e-43 comGC U competence protein ComGC
HPEHFLOH_00965 1.3e-188 comGB NU type II secretion system
HPEHFLOH_00966 6.9e-173 comGA NU Type II IV secretion system protein
HPEHFLOH_00967 8.3e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPEHFLOH_00968 8.3e-131 yebC K Transcriptional regulatory protein
HPEHFLOH_00969 3e-48 S DsrE/DsrF-like family
HPEHFLOH_00970 1.2e-163 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HPEHFLOH_00971 1.9e-181 ccpA K catabolite control protein A
HPEHFLOH_00972 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HPEHFLOH_00973 1.1e-80 K helix_turn_helix, mercury resistance
HPEHFLOH_00974 2.8e-56
HPEHFLOH_00975 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HPEHFLOH_00976 2.6e-158 ykuT M mechanosensitive ion channel
HPEHFLOH_00977 8.3e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HPEHFLOH_00978 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HPEHFLOH_00979 6.5e-87 ykuL S (CBS) domain
HPEHFLOH_00980 1.7e-93 S Phosphoesterase
HPEHFLOH_00981 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPEHFLOH_00982 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HPEHFLOH_00983 1.9e-92 yslB S Protein of unknown function (DUF2507)
HPEHFLOH_00984 3.3e-52 trxA O Belongs to the thioredoxin family
HPEHFLOH_00985 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPEHFLOH_00986 8e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HPEHFLOH_00987 1.6e-48 yrzB S Belongs to the UPF0473 family
HPEHFLOH_00988 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPEHFLOH_00989 2.4e-43 yrzL S Belongs to the UPF0297 family
HPEHFLOH_00990 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPEHFLOH_00991 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HPEHFLOH_00992 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HPEHFLOH_00993 1.5e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPEHFLOH_00994 2.8e-29 yajC U Preprotein translocase
HPEHFLOH_00995 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPEHFLOH_00996 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPEHFLOH_00997 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPEHFLOH_00998 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPEHFLOH_00999 9.6e-89
HPEHFLOH_01000 0.0 S Bacterial membrane protein YfhO
HPEHFLOH_01001 1.3e-72
HPEHFLOH_01002 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPEHFLOH_01003 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPEHFLOH_01004 2.7e-154 ymdB S YmdB-like protein
HPEHFLOH_01005 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
HPEHFLOH_01006 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPEHFLOH_01007 2.1e-230 cinA 3.5.1.42 S Belongs to the CinA family
HPEHFLOH_01008 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPEHFLOH_01009 5.7e-110 ymfM S Helix-turn-helix domain
HPEHFLOH_01010 2.9e-251 ymfH S Peptidase M16
HPEHFLOH_01011 1.9e-231 ymfF S Peptidase M16 inactive domain protein
HPEHFLOH_01012 4.2e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
HPEHFLOH_01013 1.5e-155 aatB ET ABC transporter substrate-binding protein
HPEHFLOH_01014 7.4e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPEHFLOH_01015 4.6e-109 glnP P ABC transporter permease
HPEHFLOH_01016 3.5e-146 minD D Belongs to the ParA family
HPEHFLOH_01017 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HPEHFLOH_01018 3.6e-88 mreD M rod shape-determining protein MreD
HPEHFLOH_01019 5.8e-144 mreC M Involved in formation and maintenance of cell shape
HPEHFLOH_01020 2.8e-161 mreB D cell shape determining protein MreB
HPEHFLOH_01021 3e-53 radC L DNA repair protein
HPEHFLOH_01022 1.1e-53 radC L DNA repair protein
HPEHFLOH_01023 5.8e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HPEHFLOH_01024 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPEHFLOH_01025 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HPEHFLOH_01026 4e-234 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HPEHFLOH_01027 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HPEHFLOH_01028 3.2e-217 iscS2 2.8.1.7 E Aminotransferase class V
HPEHFLOH_01029 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HPEHFLOH_01030 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
HPEHFLOH_01031 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPEHFLOH_01032 3.3e-112 yktB S Belongs to the UPF0637 family
HPEHFLOH_01033 7.3e-80 yueI S Protein of unknown function (DUF1694)
HPEHFLOH_01034 3.1e-110 S Protein of unknown function (DUF1648)
HPEHFLOH_01035 1.7e-44 czrA K Helix-turn-helix domain
HPEHFLOH_01036 5.1e-232 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HPEHFLOH_01037 9.2e-42 2.7.1.191 G PTS system fructose IIA component
HPEHFLOH_01038 2.7e-104 G PTS system mannose fructose sorbose family IID component
HPEHFLOH_01039 1.8e-102 G PTS system sorbose-specific iic component
HPEHFLOH_01040 6e-66 2.7.1.191 G PTS system sorbose subfamily IIB component
HPEHFLOH_01041 5.9e-95 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HPEHFLOH_01042 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HPEHFLOH_01043 2.3e-237 rarA L recombination factor protein RarA
HPEHFLOH_01044 1.5e-38
HPEHFLOH_01045 6.2e-82 usp6 T universal stress protein
HPEHFLOH_01046 3.1e-201 bla2 3.5.2.6 V Beta-lactamase enzyme family
HPEHFLOH_01047 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HPEHFLOH_01048 1.5e-294 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HPEHFLOH_01049 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HPEHFLOH_01050 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HPEHFLOH_01051 1.6e-177 S Protein of unknown function (DUF2785)
HPEHFLOH_01052 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
HPEHFLOH_01053 7e-142 metQ M Belongs to the nlpA lipoprotein family
HPEHFLOH_01054 1.7e-109 metI U ABC transporter permease
HPEHFLOH_01055 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPEHFLOH_01056 3.6e-48 gcsH2 E glycine cleavage
HPEHFLOH_01057 9.3e-220 rodA D Belongs to the SEDS family
HPEHFLOH_01058 3.3e-33 S Protein of unknown function (DUF2969)
HPEHFLOH_01059 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HPEHFLOH_01060 1.7e-179 mbl D Cell shape determining protein MreB Mrl
HPEHFLOH_01061 2.1e-102 J Acetyltransferase (GNAT) domain
HPEHFLOH_01062 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPEHFLOH_01063 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HPEHFLOH_01064 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPEHFLOH_01065 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPEHFLOH_01066 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPEHFLOH_01067 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPEHFLOH_01068 1.8e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPEHFLOH_01069 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPEHFLOH_01070 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HPEHFLOH_01071 1.1e-231 pyrP F Permease
HPEHFLOH_01072 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPEHFLOH_01073 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPEHFLOH_01074 2.2e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HPEHFLOH_01075 1.6e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPEHFLOH_01076 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPEHFLOH_01077 9.3e-109 tdk 2.7.1.21 F thymidine kinase
HPEHFLOH_01078 3.8e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HPEHFLOH_01079 5.9e-137 cobQ S glutamine amidotransferase
HPEHFLOH_01080 2.8e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
HPEHFLOH_01081 5.9e-191 ampC V Beta-lactamase
HPEHFLOH_01082 5.2e-29
HPEHFLOH_01083 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HPEHFLOH_01084 1.9e-58
HPEHFLOH_01085 7.4e-127
HPEHFLOH_01086 0.0 yfiC V ABC transporter
HPEHFLOH_01087 0.0 ycfI V ABC transporter, ATP-binding protein
HPEHFLOH_01088 3.3e-65 S Protein of unknown function (DUF1093)
HPEHFLOH_01089 3.8e-135 yxkH G Polysaccharide deacetylase
HPEHFLOH_01091 6.6e-22 chpA T Toxic component of a toxin-antitoxin (TA) module
HPEHFLOH_01092 3.7e-20 T SpoVT / AbrB like domain
HPEHFLOH_01093 8e-24 hol S Bacteriophage holin
HPEHFLOH_01094 5.2e-47
HPEHFLOH_01095 1.5e-177 M Glycosyl hydrolases family 25
HPEHFLOH_01096 7.3e-59 cotH M CotH kinase protein
HPEHFLOH_01098 6.9e-161 S Prophage endopeptidase tail
HPEHFLOH_01099 9.6e-123 S Phage tail protein
HPEHFLOH_01100 0.0 S peptidoglycan catabolic process
HPEHFLOH_01101 3.1e-102 S Bacteriophage Gp15 protein
HPEHFLOH_01103 3.4e-78
HPEHFLOH_01104 1.6e-67 S Minor capsid protein from bacteriophage
HPEHFLOH_01105 1e-49 S Minor capsid protein
HPEHFLOH_01106 1.4e-54 S Minor capsid protein
HPEHFLOH_01107 8.1e-09
HPEHFLOH_01108 8.3e-101
HPEHFLOH_01109 1.5e-45 S Phage minor structural protein GP20
HPEHFLOH_01110 2.7e-168 S Phage minor capsid protein 2
HPEHFLOH_01111 1.2e-245 S Phage portal protein, SPP1 Gp6-like
HPEHFLOH_01112 1.7e-262 S Phage terminase large subunit
HPEHFLOH_01113 1e-79 xtmA L Terminase small subunit
HPEHFLOH_01114 1.1e-27
HPEHFLOH_01115 7.4e-47 S Beta protein
HPEHFLOH_01116 2e-42 S Psort location Cytoplasmic, score
HPEHFLOH_01118 1.8e-14
HPEHFLOH_01119 2.4e-27
HPEHFLOH_01120 1.5e-20 S YopX protein
HPEHFLOH_01122 7.1e-65 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HPEHFLOH_01123 7.3e-89
HPEHFLOH_01124 7e-49
HPEHFLOH_01125 6.1e-147 3.1.3.16 L DnaD domain protein
HPEHFLOH_01126 4e-64
HPEHFLOH_01127 5.4e-55 S Bacteriophage Mu Gam like protein
HPEHFLOH_01129 3.9e-15 S Domain of unknown function (DUF1508)
HPEHFLOH_01130 4.4e-78
HPEHFLOH_01131 2.2e-53
HPEHFLOH_01134 1.7e-16 K sequence-specific DNA binding
HPEHFLOH_01135 1.2e-09 S Pfam:Peptidase_M78
HPEHFLOH_01137 1.5e-181 S Type I restriction enzyme R protein N terminus (HSDR_N)
HPEHFLOH_01141 0.0 S AAA ATPase domain
HPEHFLOH_01142 5.8e-174 dam2 2.1.1.72 L DNA methyltransferase
HPEHFLOH_01143 5.6e-219 int L Belongs to the 'phage' integrase family
HPEHFLOH_01145 8.9e-30
HPEHFLOH_01147 2e-38
HPEHFLOH_01148 3.2e-43
HPEHFLOH_01149 7.3e-83 K MarR family
HPEHFLOH_01150 0.0 bztC D nuclear chromosome segregation
HPEHFLOH_01151 3.1e-166 M MucBP domain
HPEHFLOH_01152 1.5e-14
HPEHFLOH_01153 4.7e-16
HPEHFLOH_01154 1.5e-14
HPEHFLOH_01155 4.2e-18
HPEHFLOH_01156 2.1e-17
HPEHFLOH_01157 1.1e-18
HPEHFLOH_01158 1.9e-18
HPEHFLOH_01159 1.6e-16
HPEHFLOH_01160 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
HPEHFLOH_01161 2.3e-62 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HPEHFLOH_01162 4.5e-198 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HPEHFLOH_01163 0.0 macB3 V ABC transporter, ATP-binding protein
HPEHFLOH_01164 6.8e-24
HPEHFLOH_01165 3.9e-259 pgi 5.3.1.9 G Belongs to the GPI family
HPEHFLOH_01166 9.7e-155 glcU U sugar transport
HPEHFLOH_01167 3.2e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
HPEHFLOH_01168 2.9e-287 yclK 2.7.13.3 T Histidine kinase
HPEHFLOH_01169 1.6e-134 K response regulator
HPEHFLOH_01170 3e-243 XK27_08635 S UPF0210 protein
HPEHFLOH_01171 8.9e-38 gcvR T Belongs to the UPF0237 family
HPEHFLOH_01172 1.5e-169 EG EamA-like transporter family
HPEHFLOH_01174 7.7e-92 S ECF-type riboflavin transporter, S component
HPEHFLOH_01175 8.6e-48
HPEHFLOH_01176 1.4e-212 yceI EGP Major facilitator Superfamily
HPEHFLOH_01177 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
HPEHFLOH_01178 3.8e-23
HPEHFLOH_01180 5.9e-160 S Alpha/beta hydrolase of unknown function (DUF915)
HPEHFLOH_01181 2.8e-173 ykfC 3.4.14.13 M NlpC/P60 family
HPEHFLOH_01182 3.3e-80 K AsnC family
HPEHFLOH_01183 7.6e-35
HPEHFLOH_01184 3.3e-33
HPEHFLOH_01185 6.6e-218 2.7.7.65 T diguanylate cyclase
HPEHFLOH_01186 7.8e-296 S ABC transporter, ATP-binding protein
HPEHFLOH_01187 2e-106 3.2.2.20 K acetyltransferase
HPEHFLOH_01188 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPEHFLOH_01189 6e-39
HPEHFLOH_01190 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HPEHFLOH_01191 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPEHFLOH_01192 5e-162 degV S Uncharacterised protein, DegV family COG1307
HPEHFLOH_01193 6.8e-229 hom1 1.1.1.3 E Homoserine dehydrogenase
HPEHFLOH_01194 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HPEHFLOH_01195 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HPEHFLOH_01196 3.1e-176 XK27_08835 S ABC transporter
HPEHFLOH_01197 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HPEHFLOH_01198 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
HPEHFLOH_01199 5.7e-258 npr 1.11.1.1 C NADH oxidase
HPEHFLOH_01200 5.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HPEHFLOH_01201 3.1e-136 terC P membrane
HPEHFLOH_01202 2.4e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HPEHFLOH_01203 1.9e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPEHFLOH_01204 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HPEHFLOH_01205 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HPEHFLOH_01206 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPEHFLOH_01207 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HPEHFLOH_01208 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPEHFLOH_01209 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HPEHFLOH_01210 2.7e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPEHFLOH_01211 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HPEHFLOH_01212 1.9e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HPEHFLOH_01213 5e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
HPEHFLOH_01214 4.6e-216 ysaA V RDD family
HPEHFLOH_01215 7.6e-166 corA P CorA-like Mg2+ transporter protein
HPEHFLOH_01216 2.1e-55 S Domain of unknown function (DU1801)
HPEHFLOH_01217 5.9e-91 rmeB K transcriptional regulator, MerR family
HPEHFLOH_01218 3.1e-37 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
HPEHFLOH_01219 1e-99 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
HPEHFLOH_01220 4.3e-97 J glyoxalase III activity
HPEHFLOH_01221 3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPEHFLOH_01222 5.9e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPEHFLOH_01223 3.1e-33
HPEHFLOH_01224 3.2e-112 S Protein of unknown function (DUF1211)
HPEHFLOH_01225 0.0 ydgH S MMPL family
HPEHFLOH_01226 2.1e-285 M domain protein
HPEHFLOH_01227 1.5e-74 yjcF S Acetyltransferase (GNAT) domain
HPEHFLOH_01228 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HPEHFLOH_01229 1.6e-60 glpQ 3.1.4.46 C phosphodiesterase
HPEHFLOH_01230 6.7e-216 glpQ 3.1.4.46 C phosphodiesterase
HPEHFLOH_01231 8.9e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HPEHFLOH_01232 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
HPEHFLOH_01233 5.9e-182 3.6.4.13 S domain, Protein
HPEHFLOH_01234 1e-167 S Polyphosphate kinase 2 (PPK2)
HPEHFLOH_01235 1.2e-97 drgA C Nitroreductase family
HPEHFLOH_01236 7e-178 iunH2 3.2.2.1 F nucleoside hydrolase
HPEHFLOH_01237 2.2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPEHFLOH_01238 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
HPEHFLOH_01239 2.3e-157 ccpB 5.1.1.1 K lacI family
HPEHFLOH_01240 8.1e-117 K Helix-turn-helix domain, rpiR family
HPEHFLOH_01241 6e-177 S Oxidoreductase family, NAD-binding Rossmann fold
HPEHFLOH_01242 5.5e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
HPEHFLOH_01243 0.0 yjcE P Sodium proton antiporter
HPEHFLOH_01244 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPEHFLOH_01245 3.7e-107 pncA Q Isochorismatase family
HPEHFLOH_01246 2.7e-132
HPEHFLOH_01247 5.1e-125 skfE V ABC transporter
HPEHFLOH_01248 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
HPEHFLOH_01249 1.2e-45 S Enterocin A Immunity
HPEHFLOH_01250 4.5e-174 D Alpha beta
HPEHFLOH_01251 0.0 pepF2 E Oligopeptidase F
HPEHFLOH_01252 1.3e-72 K Transcriptional regulator
HPEHFLOH_01253 8.7e-164
HPEHFLOH_01255 3.9e-57
HPEHFLOH_01256 5.9e-48
HPEHFLOH_01257 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPEHFLOH_01258 2.7e-67
HPEHFLOH_01259 8.4e-145 yjfP S Dienelactone hydrolase family
HPEHFLOH_01260 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
HPEHFLOH_01261 4.2e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HPEHFLOH_01262 5.2e-47
HPEHFLOH_01263 6.3e-45
HPEHFLOH_01264 5e-82 yybC S Protein of unknown function (DUF2798)
HPEHFLOH_01265 1.7e-73
HPEHFLOH_01266 4e-60
HPEHFLOH_01267 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HPEHFLOH_01268 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
HPEHFLOH_01269 1.6e-79 uspA T universal stress protein
HPEHFLOH_01270 6.6e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HPEHFLOH_01271 1.7e-48 K Cro/C1-type HTH DNA-binding domain
HPEHFLOH_01272 3.3e-21 S Protein of unknown function (DUF2929)
HPEHFLOH_01273 1e-223 lsgC M Glycosyl transferases group 1
HPEHFLOH_01274 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HPEHFLOH_01275 3.2e-166 S Putative esterase
HPEHFLOH_01276 2.4e-130 gntR2 K Transcriptional regulator
HPEHFLOH_01277 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPEHFLOH_01278 8.9e-139
HPEHFLOH_01279 1.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPEHFLOH_01280 5.5e-138 rrp8 K LytTr DNA-binding domain
HPEHFLOH_01281 9.4e-92 M1-874 K Domain of unknown function (DUF1836)
HPEHFLOH_01282 1.7e-60
HPEHFLOH_01283 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
HPEHFLOH_01284 4.4e-58
HPEHFLOH_01285 1.6e-236 yhdP S Transporter associated domain
HPEHFLOH_01286 4.9e-87 nrdI F Belongs to the NrdI family
HPEHFLOH_01287 2.9e-269 yjcE P Sodium proton antiporter
HPEHFLOH_01288 1.1e-212 yttB EGP Major facilitator Superfamily
HPEHFLOH_01289 5e-63 K helix_turn_helix, mercury resistance
HPEHFLOH_01290 1.8e-173 C Zinc-binding dehydrogenase
HPEHFLOH_01291 8.5e-57 S SdpI/YhfL protein family
HPEHFLOH_01292 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPEHFLOH_01293 3.6e-260 gabR K Bacterial regulatory proteins, gntR family
HPEHFLOH_01294 5e-218 patA 2.6.1.1 E Aminotransferase
HPEHFLOH_01295 1.9e-158 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPEHFLOH_01296 3e-18
HPEHFLOH_01297 1.7e-126 S membrane transporter protein
HPEHFLOH_01298 1.5e-30 mleR K LysR family
HPEHFLOH_01299 6.9e-53 mleR K LysR family
HPEHFLOH_01300 5.6e-115 ylbE GM NAD(P)H-binding
HPEHFLOH_01301 8.2e-96 wecD K Acetyltransferase (GNAT) family
HPEHFLOH_01302 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HPEHFLOH_01303 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HPEHFLOH_01304 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
HPEHFLOH_01305 6.2e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPEHFLOH_01306 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HPEHFLOH_01307 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPEHFLOH_01308 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HPEHFLOH_01309 7.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HPEHFLOH_01310 6.4e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPEHFLOH_01311 1.6e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HPEHFLOH_01312 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HPEHFLOH_01313 1e-298 pucR QT Purine catabolism regulatory protein-like family
HPEHFLOH_01314 3.5e-236 pbuX F xanthine permease
HPEHFLOH_01315 2.4e-221 pbuG S Permease family
HPEHFLOH_01316 5.6e-161 GM NmrA-like family
HPEHFLOH_01317 6.5e-156 T EAL domain
HPEHFLOH_01318 2.6e-94
HPEHFLOH_01319 8.7e-190 pgaC GT2 M Glycosyl transferase
HPEHFLOH_01322 3e-252 dtpT U amino acid peptide transporter
HPEHFLOH_01323 1.3e-150 yjjH S Calcineurin-like phosphoesterase
HPEHFLOH_01326 9.8e-39 pgaC GT2 M Glycosyl transferase
HPEHFLOH_01327 2e-123 2.1.1.14 E Methionine synthase
HPEHFLOH_01328 5.4e-215 purD 6.3.4.13 F Belongs to the GARS family
HPEHFLOH_01329 8.6e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HPEHFLOH_01330 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPEHFLOH_01331 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HPEHFLOH_01332 4.8e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPEHFLOH_01333 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPEHFLOH_01334 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPEHFLOH_01335 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HPEHFLOH_01336 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HPEHFLOH_01337 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPEHFLOH_01338 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPEHFLOH_01339 1.5e-223 XK27_09615 1.3.5.4 S reductase
HPEHFLOH_01340 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
HPEHFLOH_01341 4.9e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HPEHFLOH_01342 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
HPEHFLOH_01343 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HPEHFLOH_01344 8.3e-148 S Alpha/beta hydrolase of unknown function (DUF915)
HPEHFLOH_01345 5.8e-180 ansA 3.5.1.1 EJ Asparaginase
HPEHFLOH_01346 1.7e-139 cysA V ABC transporter, ATP-binding protein
HPEHFLOH_01347 0.0 V FtsX-like permease family
HPEHFLOH_01348 3e-41
HPEHFLOH_01349 3.9e-60 gntR1 K Transcriptional regulator, GntR family
HPEHFLOH_01350 6.9e-164 V ABC transporter, ATP-binding protein
HPEHFLOH_01351 5.1e-137
HPEHFLOH_01352 6.7e-81 uspA T universal stress protein
HPEHFLOH_01353 4e-34
HPEHFLOH_01354 5.5e-71 gtcA S Teichoic acid glycosylation protein
HPEHFLOH_01355 1.1e-88
HPEHFLOH_01356 5e-51
HPEHFLOH_01358 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
HPEHFLOH_01359 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
HPEHFLOH_01360 5.4e-118
HPEHFLOH_01361 1.5e-52
HPEHFLOH_01363 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HPEHFLOH_01364 3.6e-282 thrC 4.2.3.1 E Threonine synthase
HPEHFLOH_01365 2.9e-145 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HPEHFLOH_01366 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
HPEHFLOH_01367 2.8e-96 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HPEHFLOH_01368 1.7e-102 3.6.1.13 L Belongs to the Nudix hydrolase family
HPEHFLOH_01369 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
HPEHFLOH_01370 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
HPEHFLOH_01371 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
HPEHFLOH_01372 1.4e-211 S Bacterial protein of unknown function (DUF871)
HPEHFLOH_01373 2.3e-231 S Sterol carrier protein domain
HPEHFLOH_01374 1e-21
HPEHFLOH_01375 8.2e-34 K sequence-specific DNA binding
HPEHFLOH_01376 1.7e-191 EGP Major facilitator Superfamily
HPEHFLOH_01377 3.6e-88 niaR S 3H domain
HPEHFLOH_01378 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPEHFLOH_01379 1.3e-117 K Transcriptional regulator
HPEHFLOH_01380 3.2e-154 V ABC transporter
HPEHFLOH_01381 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
HPEHFLOH_01382 1.1e-245 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HPEHFLOH_01383 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPEHFLOH_01384 8.6e-297 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPEHFLOH_01385 5.1e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HPEHFLOH_01386 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HPEHFLOH_01387 1.8e-130 gntR K UTRA
HPEHFLOH_01388 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
HPEHFLOH_01389 2.5e-121 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HPEHFLOH_01390 1.8e-81
HPEHFLOH_01391 9.8e-152 S hydrolase
HPEHFLOH_01392 6.5e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPEHFLOH_01393 8.3e-152 EG EamA-like transporter family
HPEHFLOH_01394 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HPEHFLOH_01395 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HPEHFLOH_01396 1.9e-231
HPEHFLOH_01397 1.9e-77 fld C Flavodoxin
HPEHFLOH_01398 0.0 M Bacterial Ig-like domain (group 3)
HPEHFLOH_01399 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HPEHFLOH_01400 2.7e-32
HPEHFLOH_01401 8.3e-129 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
HPEHFLOH_01402 1.4e-267 ycaM E amino acid
HPEHFLOH_01403 3e-78 K Winged helix DNA-binding domain
HPEHFLOH_01404 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
HPEHFLOH_01405 5.7e-163 akr5f 1.1.1.346 S reductase
HPEHFLOH_01406 1.3e-162 K Transcriptional regulator
HPEHFLOH_01408 1.8e-84 hmpT S Pfam:DUF3816
HPEHFLOH_01409 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPEHFLOH_01410 3.9e-111
HPEHFLOH_01411 2.8e-153 M Glycosyl hydrolases family 25
HPEHFLOH_01412 2e-143 yvpB S Peptidase_C39 like family
HPEHFLOH_01413 1.4e-92 yueI S Protein of unknown function (DUF1694)
HPEHFLOH_01414 1.6e-115 S Protein of unknown function (DUF554)
HPEHFLOH_01415 1.9e-147 KT helix_turn_helix, mercury resistance
HPEHFLOH_01416 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPEHFLOH_01417 6.6e-95 S Protein of unknown function (DUF1440)
HPEHFLOH_01418 1.2e-173 hrtB V ABC transporter permease
HPEHFLOH_01419 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HPEHFLOH_01420 1.4e-90 2.7.7.65 T phosphorelay sensor kinase activity
HPEHFLOH_01421 1.5e-183 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HPEHFLOH_01422 8.1e-99 1.5.1.3 H RibD C-terminal domain
HPEHFLOH_01423 1.7e-186 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HPEHFLOH_01424 7.5e-118 S Membrane
HPEHFLOH_01425 1.2e-155 mleP3 S Membrane transport protein
HPEHFLOH_01426 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HPEHFLOH_01427 7.6e-190 ynfM EGP Major facilitator Superfamily
HPEHFLOH_01428 2.9e-122 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPEHFLOH_01429 3.2e-270 lmrB EGP Major facilitator Superfamily
HPEHFLOH_01430 4e-76 S Domain of unknown function (DUF4811)
HPEHFLOH_01431 6.9e-101 rimL J Acetyltransferase (GNAT) domain
HPEHFLOH_01432 9.3e-173 S Conserved hypothetical protein 698
HPEHFLOH_01433 3.7e-151 rlrG K Transcriptional regulator
HPEHFLOH_01434 9e-297 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HPEHFLOH_01435 7.6e-267 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
HPEHFLOH_01437 4.3e-51 lytE M LysM domain
HPEHFLOH_01438 2e-91 ogt 2.1.1.63 L Methyltransferase
HPEHFLOH_01439 1.4e-167 natA S ABC transporter, ATP-binding protein
HPEHFLOH_01440 4.7e-211 natB CP ABC-2 family transporter protein
HPEHFLOH_01441 1e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPEHFLOH_01442 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HPEHFLOH_01443 3.2e-76 yphH S Cupin domain
HPEHFLOH_01444 9.8e-79 K transcriptional regulator, MerR family
HPEHFLOH_01445 2e-236 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HPEHFLOH_01446 0.0 ylbB V ABC transporter permease
HPEHFLOH_01447 3.7e-120 macB V ABC transporter, ATP-binding protein
HPEHFLOH_01449 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPEHFLOH_01450 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HPEHFLOH_01451 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPEHFLOH_01453 3.8e-84
HPEHFLOH_01454 2.8e-85 yvbK 3.1.3.25 K GNAT family
HPEHFLOH_01455 1.3e-35
HPEHFLOH_01456 8.2e-48
HPEHFLOH_01457 1.4e-110 pgm8 G Histidine phosphatase superfamily (branch 1)
HPEHFLOH_01458 3.8e-63 S Domain of unknown function (DUF4440)
HPEHFLOH_01459 6.9e-156 K LysR substrate binding domain
HPEHFLOH_01460 1.9e-104 GM NAD(P)H-binding
HPEHFLOH_01461 5.8e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HPEHFLOH_01462 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
HPEHFLOH_01463 1.3e-34
HPEHFLOH_01464 6.1e-76 T Belongs to the universal stress protein A family
HPEHFLOH_01465 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HPEHFLOH_01466 4.4e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPEHFLOH_01467 2.1e-31
HPEHFLOH_01468 9.2e-104 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HPEHFLOH_01469 1.3e-221 patB 4.4.1.8 E Aminotransferase, class I
HPEHFLOH_01470 7.4e-102 M Protein of unknown function (DUF3737)
HPEHFLOH_01471 1.2e-194 C Aldo/keto reductase family
HPEHFLOH_01473 0.0 mdlB V ABC transporter
HPEHFLOH_01474 0.0 mdlA V ABC transporter
HPEHFLOH_01475 6.7e-246 EGP Major facilitator Superfamily
HPEHFLOH_01478 8e-09
HPEHFLOH_01479 3.8e-187 yhgE V domain protein
HPEHFLOH_01480 1.5e-95 K Transcriptional regulator (TetR family)
HPEHFLOH_01481 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPEHFLOH_01482 1.4e-138 endA F DNA RNA non-specific endonuclease
HPEHFLOH_01483 7.7e-97 speG J Acetyltransferase (GNAT) domain
HPEHFLOH_01484 5.7e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
HPEHFLOH_01485 4.5e-122 2.7.1.89 M Phosphotransferase enzyme family
HPEHFLOH_01486 3.8e-221 S CAAX protease self-immunity
HPEHFLOH_01487 3.2e-308 ybiT S ABC transporter, ATP-binding protein
HPEHFLOH_01488 5.3e-147 3.1.3.102, 3.1.3.104 S hydrolase
HPEHFLOH_01489 0.0 S Predicted membrane protein (DUF2207)
HPEHFLOH_01490 0.0 uvrA3 L excinuclease ABC
HPEHFLOH_01491 4.4e-77 uvrA3 L excinuclease ABC
HPEHFLOH_01492 1.1e-34 EGP Major facilitator Superfamily
HPEHFLOH_01493 2.5e-159 EGP Major facilitator Superfamily
HPEHFLOH_01494 6.4e-173 ropB K Helix-turn-helix XRE-family like proteins
HPEHFLOH_01495 4.7e-176 pepR1 3.4.11.5 I Releases the N-terminal proline from various substrates
HPEHFLOH_01496 2e-118 puuP_1 E Amino acid permease
HPEHFLOH_01497 1.2e-112 puuP_1 E Amino acid permease
HPEHFLOH_01498 3.2e-232 yxiO S Vacuole effluxer Atg22 like
HPEHFLOH_01499 1.1e-255 npp S type I phosphodiesterase nucleotide pyrophosphatase
HPEHFLOH_01500 2e-160 I alpha/beta hydrolase fold
HPEHFLOH_01501 4.8e-131 treR K UTRA
HPEHFLOH_01502 1.4e-238
HPEHFLOH_01503 5.6e-39 S Cytochrome B5
HPEHFLOH_01504 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPEHFLOH_01505 9e-217 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HPEHFLOH_01506 6.8e-127 yliE T EAL domain
HPEHFLOH_01507 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPEHFLOH_01508 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HPEHFLOH_01509 2e-80
HPEHFLOH_01510 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPEHFLOH_01511 2.9e-190 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPEHFLOH_01512 1.5e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPEHFLOH_01513 4.9e-22
HPEHFLOH_01514 4.4e-79
HPEHFLOH_01515 2.2e-165 K LysR substrate binding domain
HPEHFLOH_01516 2.4e-243 P Sodium:sulfate symporter transmembrane region
HPEHFLOH_01517 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HPEHFLOH_01518 4.7e-80 S response to antibiotic
HPEHFLOH_01519 4.3e-169 S response to antibiotic
HPEHFLOH_01520 8.8e-136 S zinc-ribbon domain
HPEHFLOH_01522 3.2e-37
HPEHFLOH_01523 2.7e-137 aroD S Alpha/beta hydrolase family
HPEHFLOH_01524 5.2e-177 S Phosphotransferase system, EIIC
HPEHFLOH_01525 5.1e-270 I acetylesterase activity
HPEHFLOH_01526 1.2e-223 sdrF M Collagen binding domain
HPEHFLOH_01527 1.1e-159 yicL EG EamA-like transporter family
HPEHFLOH_01528 4.4e-129 E lipolytic protein G-D-S-L family
HPEHFLOH_01529 1.7e-176 4.1.1.52 S Amidohydrolase
HPEHFLOH_01530 5.1e-113 K Transcriptional regulator C-terminal region
HPEHFLOH_01531 6.9e-47 3.6.4.12 K HxlR-like helix-turn-helix
HPEHFLOH_01532 1.2e-160 ypbG 2.7.1.2 GK ROK family
HPEHFLOH_01533 0.0 ybfG M peptidoglycan-binding domain-containing protein
HPEHFLOH_01534 3.6e-88
HPEHFLOH_01535 0.0 lmrA 3.6.3.44 V ABC transporter
HPEHFLOH_01536 5e-93 rmaB K Transcriptional regulator, MarR family
HPEHFLOH_01537 7.1e-159 ccpB 5.1.1.1 K lacI family
HPEHFLOH_01538 8.7e-121 yceE S haloacid dehalogenase-like hydrolase
HPEHFLOH_01539 1.3e-119 drgA C Nitroreductase family
HPEHFLOH_01540 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HPEHFLOH_01541 7.1e-116 cmpC S ATPases associated with a variety of cellular activities
HPEHFLOH_01542 8.7e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HPEHFLOH_01543 2.3e-168 XK27_00670 S ABC transporter
HPEHFLOH_01544 1e-260
HPEHFLOH_01545 7.3e-62
HPEHFLOH_01546 1.1e-189 S Cell surface protein
HPEHFLOH_01547 2.3e-91 S WxL domain surface cell wall-binding
HPEHFLOH_01548 5.3e-63 acuB S Domain in cystathionine beta-synthase and other proteins.
HPEHFLOH_01549 1e-31 cp12 S Domain in cystathionine beta-synthase and other proteins.
HPEHFLOH_01550 3.3e-124 livF E ABC transporter
HPEHFLOH_01551 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
HPEHFLOH_01552 5.3e-141 livM E Branched-chain amino acid transport system / permease component
HPEHFLOH_01553 6.5e-154 livH U Branched-chain amino acid transport system / permease component
HPEHFLOH_01554 1.2e-211 livJ E Receptor family ligand binding region
HPEHFLOH_01556 7e-33
HPEHFLOH_01557 1.7e-113 zmp3 O Zinc-dependent metalloprotease
HPEHFLOH_01558 2.8e-82 gtrA S GtrA-like protein
HPEHFLOH_01559 8.5e-122 K Helix-turn-helix XRE-family like proteins
HPEHFLOH_01560 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
HPEHFLOH_01561 6.8e-72 T Belongs to the universal stress protein A family
HPEHFLOH_01562 6.9e-46
HPEHFLOH_01563 7.1e-116 S SNARE associated Golgi protein
HPEHFLOH_01564 2e-49 K Transcriptional regulator, ArsR family
HPEHFLOH_01565 1.2e-95 cadD P Cadmium resistance transporter
HPEHFLOH_01566 0.0 yhcA V ABC transporter, ATP-binding protein
HPEHFLOH_01567 0.0 P Concanavalin A-like lectin/glucanases superfamily
HPEHFLOH_01568 6.1e-113 P Concanavalin A-like lectin/glucanases superfamily
HPEHFLOH_01569 7.4e-64
HPEHFLOH_01570 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
HPEHFLOH_01571 7.2e-55
HPEHFLOH_01572 5.3e-150 dicA K Helix-turn-helix domain
HPEHFLOH_01573 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPEHFLOH_01574 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HPEHFLOH_01575 2.7e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEHFLOH_01576 2.9e-278 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPEHFLOH_01577 9.7e-186 1.1.1.219 GM Male sterility protein
HPEHFLOH_01578 2.7e-76 K helix_turn_helix, mercury resistance
HPEHFLOH_01579 7.3e-63 M LysM domain
HPEHFLOH_01580 2.3e-95 M Lysin motif
HPEHFLOH_01581 4.7e-108 S SdpI/YhfL protein family
HPEHFLOH_01582 1.8e-54 nudA S ASCH
HPEHFLOH_01583 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
HPEHFLOH_01584 5.5e-92
HPEHFLOH_01585 1.5e-120 tag 3.2.2.20 L Methyladenine glycosylase
HPEHFLOH_01586 3.3e-219 T diguanylate cyclase
HPEHFLOH_01587 1.2e-73 S Psort location Cytoplasmic, score
HPEHFLOH_01588 1.8e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HPEHFLOH_01589 8.6e-218 ykiI
HPEHFLOH_01590 6.5e-301 V ABC transporter
HPEHFLOH_01591 1.8e-18 V ABC transporter
HPEHFLOH_01592 2.1e-299 XK27_09600 V ABC transporter, ATP-binding protein
HPEHFLOH_01593 3.5e-42
HPEHFLOH_01594 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
HPEHFLOH_01595 7.7e-163 IQ KR domain
HPEHFLOH_01597 7.4e-71
HPEHFLOH_01598 1.3e-143 K Helix-turn-helix XRE-family like proteins
HPEHFLOH_01599 2.8e-266 yjeM E Amino Acid
HPEHFLOH_01600 1.1e-65 lysM M LysM domain
HPEHFLOH_01601 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HPEHFLOH_01602 4.6e-213 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HPEHFLOH_01603 0.0 ctpA 3.6.3.54 P P-type ATPase
HPEHFLOH_01604 2.7e-42 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HPEHFLOH_01605 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HPEHFLOH_01606 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPEHFLOH_01607 8.5e-118 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPEHFLOH_01608 6e-140 K Helix-turn-helix domain
HPEHFLOH_01609 2.9e-38 S TfoX C-terminal domain
HPEHFLOH_01610 1e-81 hpk9 2.7.13.3 T GHKL domain
HPEHFLOH_01611 4.1e-137 hpk9 2.7.13.3 T GHKL domain
HPEHFLOH_01612 1.6e-261
HPEHFLOH_01613 1.3e-75
HPEHFLOH_01614 9.2e-187 S Cell surface protein
HPEHFLOH_01615 1.7e-101 S WxL domain surface cell wall-binding
HPEHFLOH_01616 1.7e-179 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
HPEHFLOH_01617 3.8e-69 S Iron-sulphur cluster biosynthesis
HPEHFLOH_01618 1e-27 S GyrI-like small molecule binding domain
HPEHFLOH_01619 1.9e-74 S GyrI-like small molecule binding domain
HPEHFLOH_01620 1.2e-186 S Cell surface protein
HPEHFLOH_01621 7.5e-101 S WxL domain surface cell wall-binding
HPEHFLOH_01622 1.1e-62
HPEHFLOH_01623 9.4e-154 NU Mycoplasma protein of unknown function, DUF285
HPEHFLOH_01624 5.9e-117
HPEHFLOH_01625 4.4e-115 S Haloacid dehalogenase-like hydrolase
HPEHFLOH_01626 4.7e-57 K Transcriptional regulator PadR-like family
HPEHFLOH_01627 2.1e-120 M1-1017
HPEHFLOH_01628 2e-61 K Transcriptional regulator, HxlR family
HPEHFLOH_01629 3.9e-210 ytbD EGP Major facilitator Superfamily
HPEHFLOH_01630 1.4e-94 M ErfK YbiS YcfS YnhG
HPEHFLOH_01631 0.0 asnB 6.3.5.4 E Asparagine synthase
HPEHFLOH_01632 6.3e-134 K LytTr DNA-binding domain
HPEHFLOH_01633 3e-205 2.7.13.3 T GHKL domain
HPEHFLOH_01634 7.9e-100 fadR K Bacterial regulatory proteins, tetR family
HPEHFLOH_01635 1.8e-167 GM NmrA-like family
HPEHFLOH_01636 1.7e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HPEHFLOH_01637 0.0 M Glycosyl hydrolases family 25
HPEHFLOH_01638 1e-47 S Domain of unknown function (DUF1905)
HPEHFLOH_01639 1.4e-62 hxlR K HxlR-like helix-turn-helix
HPEHFLOH_01640 1.2e-115 ydfG S KR domain
HPEHFLOH_01641 7.5e-95 K Bacterial regulatory proteins, tetR family
HPEHFLOH_01642 1.2e-191 1.1.1.219 GM Male sterility protein
HPEHFLOH_01643 1.6e-100 S Protein of unknown function (DUF1211)
HPEHFLOH_01644 1.5e-180 S Aldo keto reductase
HPEHFLOH_01647 1.6e-253 yfjF U Sugar (and other) transporter
HPEHFLOH_01648 7.4e-109 K Bacterial regulatory proteins, tetR family
HPEHFLOH_01649 7.5e-169 fhuD P Periplasmic binding protein
HPEHFLOH_01650 1.1e-144 fhuC 3.6.3.34 HP ABC transporter
HPEHFLOH_01651 3.6e-177 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPEHFLOH_01652 5.5e-63 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPEHFLOH_01653 1.6e-98 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HPEHFLOH_01654 5.4e-92 K Bacterial regulatory proteins, tetR family
HPEHFLOH_01655 7.7e-163 GM NmrA-like family
HPEHFLOH_01656 2.5e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPEHFLOH_01657 1.3e-68 maa S transferase hexapeptide repeat
HPEHFLOH_01658 7.5e-152 IQ Enoyl-(Acyl carrier protein) reductase
HPEHFLOH_01659 1.3e-63 K helix_turn_helix, mercury resistance
HPEHFLOH_01660 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HPEHFLOH_01661 2.5e-173 S Bacterial protein of unknown function (DUF916)
HPEHFLOH_01662 1.4e-38 S WxL domain surface cell wall-binding
HPEHFLOH_01663 9e-184 NU Mycoplasma protein of unknown function, DUF285
HPEHFLOH_01664 8.1e-117 K Bacterial regulatory proteins, tetR family
HPEHFLOH_01665 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPEHFLOH_01666 1.7e-290 yjcE P Sodium proton antiporter
HPEHFLOH_01667 1.5e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HPEHFLOH_01668 3.3e-161 K LysR substrate binding domain
HPEHFLOH_01669 1.6e-282 1.3.5.4 C FAD binding domain
HPEHFLOH_01670 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
HPEHFLOH_01671 1.7e-84 dps P Belongs to the Dps family
HPEHFLOH_01672 2.2e-115 K UTRA
HPEHFLOH_01673 4.4e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPEHFLOH_01674 2e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEHFLOH_01675 4.1e-65
HPEHFLOH_01676 1.5e-11
HPEHFLOH_01677 9.4e-41 4.1.1.44 S Carboxymuconolactone decarboxylase family
HPEHFLOH_01678 2.2e-23 rmeD K helix_turn_helix, mercury resistance
HPEHFLOH_01679 7.6e-64 S Protein of unknown function (DUF1093)
HPEHFLOH_01680 4.2e-207 S Membrane
HPEHFLOH_01681 1.1e-43 S Protein of unknown function (DUF3781)
HPEHFLOH_01682 1e-107 ydeA S intracellular protease amidase
HPEHFLOH_01683 1.5e-42 K HxlR-like helix-turn-helix
HPEHFLOH_01684 7.2e-42 C Alcohol dehydrogenase GroES-like domain
HPEHFLOH_01685 9.3e-95 C Alcohol dehydrogenase GroES-like domain
HPEHFLOH_01686 6.5e-204 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HPEHFLOH_01687 5e-83 3.2.1.17, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPEHFLOH_01688 4.2e-71 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HPEHFLOH_01689 1.3e-103 M ErfK YbiS YcfS YnhG
HPEHFLOH_01690 5.9e-112 akr5f 1.1.1.346 S reductase
HPEHFLOH_01691 9.7e-109 GM NAD(P)H-binding
HPEHFLOH_01692 3.2e-77 3.5.4.1 GM SnoaL-like domain
HPEHFLOH_01693 4e-254 qacA EGP Fungal trichothecene efflux pump (TRI12)
HPEHFLOH_01694 7.1e-19 S Domain of unknown function (DUF4440)
HPEHFLOH_01695 5.3e-104 K Bacterial regulatory proteins, tetR family
HPEHFLOH_01696 5.5e-38 L transposase activity
HPEHFLOH_01698 8.8e-40
HPEHFLOH_01699 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPEHFLOH_01700 5.4e-171 K AI-2E family transporter
HPEHFLOH_01701 2.9e-210 xylR GK ROK family
HPEHFLOH_01702 2.4e-83
HPEHFLOH_01703 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HPEHFLOH_01704 1.7e-160
HPEHFLOH_01705 9.1e-203 KLT Protein tyrosine kinase
HPEHFLOH_01706 6.8e-25 S Protein of unknown function (DUF4064)
HPEHFLOH_01707 1.7e-96 S Domain of unknown function (DUF4352)
HPEHFLOH_01708 1.5e-74 S Psort location Cytoplasmic, score
HPEHFLOH_01709 4.1e-54
HPEHFLOH_01710 3.6e-110 S membrane transporter protein
HPEHFLOH_01711 2.3e-54 azlD S branched-chain amino acid
HPEHFLOH_01712 1.1e-130 azlC E branched-chain amino acid
HPEHFLOH_01713 1.2e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HPEHFLOH_01714 6.4e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPEHFLOH_01715 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
HPEHFLOH_01716 3.2e-124 K response regulator
HPEHFLOH_01717 1e-122 yoaK S Protein of unknown function (DUF1275)
HPEHFLOH_01718 3.4e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HPEHFLOH_01719 6.8e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPEHFLOH_01720 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
HPEHFLOH_01721 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPEHFLOH_01722 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
HPEHFLOH_01723 4.8e-157 spo0J K Belongs to the ParB family
HPEHFLOH_01724 1.8e-136 soj D Sporulation initiation inhibitor
HPEHFLOH_01725 2.7e-149 noc K Belongs to the ParB family
HPEHFLOH_01726 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HPEHFLOH_01727 4.1e-226 nupG F Nucleoside
HPEHFLOH_01728 1.5e-147 S Alpha/beta hydrolase of unknown function (DUF915)
HPEHFLOH_01729 2.1e-168 K LysR substrate binding domain
HPEHFLOH_01730 1.9e-236 EK Aminotransferase, class I
HPEHFLOH_01731 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HPEHFLOH_01732 9e-122 tcyB E ABC transporter
HPEHFLOH_01733 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPEHFLOH_01734 1.2e-117 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HPEHFLOH_01735 5.8e-79 KT response to antibiotic
HPEHFLOH_01736 1.1e-50 K Transcriptional regulator
HPEHFLOH_01737 1e-71 XK27_06920 S Protein of unknown function (DUF1700)
HPEHFLOH_01738 1.6e-126 S Putative adhesin
HPEHFLOH_01739 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPEHFLOH_01740 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HPEHFLOH_01741 1.4e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HPEHFLOH_01742 1.3e-204 S DUF218 domain
HPEHFLOH_01743 2e-127 ybbM S Uncharacterised protein family (UPF0014)
HPEHFLOH_01744 9.4e-118 ybbL S ABC transporter, ATP-binding protein
HPEHFLOH_01745 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPEHFLOH_01746 9.4e-77
HPEHFLOH_01747 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
HPEHFLOH_01748 1.1e-147 cof S haloacid dehalogenase-like hydrolase
HPEHFLOH_01749 1.1e-92 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HPEHFLOH_01750 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HPEHFLOH_01751 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
HPEHFLOH_01752 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HPEHFLOH_01753 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HPEHFLOH_01754 6.4e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPEHFLOH_01755 2e-77 merR K MerR family regulatory protein
HPEHFLOH_01756 3.8e-154 1.6.5.2 GM NmrA-like family
HPEHFLOH_01757 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPEHFLOH_01758 1.1e-126 magIII L Base excision DNA repair protein, HhH-GPD family
HPEHFLOH_01759 1.4e-08
HPEHFLOH_01760 2e-100 S NADPH-dependent FMN reductase
HPEHFLOH_01761 2.3e-237 S module of peptide synthetase
HPEHFLOH_01762 6.9e-107
HPEHFLOH_01763 9.8e-88 perR P Belongs to the Fur family
HPEHFLOH_01764 7.1e-59 S Enterocin A Immunity
HPEHFLOH_01765 5.4e-36 S Phospholipase_D-nuclease N-terminal
HPEHFLOH_01766 1.8e-169 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HPEHFLOH_01767 3.8e-104 J Acetyltransferase (GNAT) domain
HPEHFLOH_01768 1.2e-62 lrgA S LrgA family
HPEHFLOH_01769 7.3e-127 lrgB M LrgB-like family
HPEHFLOH_01770 2.5e-145 DegV S EDD domain protein, DegV family
HPEHFLOH_01771 4.1e-25
HPEHFLOH_01772 2.9e-117 yugP S Putative neutral zinc metallopeptidase
HPEHFLOH_01773 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
HPEHFLOH_01774 4.8e-165 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
HPEHFLOH_01775 1.7e-184 D Alpha beta
HPEHFLOH_01776 1.6e-197 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HPEHFLOH_01777 2.8e-257 gor 1.8.1.7 C Glutathione reductase
HPEHFLOH_01778 3.4e-55 S Enterocin A Immunity
HPEHFLOH_01779 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HPEHFLOH_01780 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPEHFLOH_01781 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HPEHFLOH_01782 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
HPEHFLOH_01783 8.1e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPEHFLOH_01785 4.3e-83
HPEHFLOH_01786 1.5e-256 yhdG E C-terminus of AA_permease
HPEHFLOH_01788 0.0 kup P Transport of potassium into the cell
HPEHFLOH_01789 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPEHFLOH_01790 3.1e-179 K AI-2E family transporter
HPEHFLOH_01791 7.6e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HPEHFLOH_01792 4.4e-59 qacC P Small Multidrug Resistance protein
HPEHFLOH_01793 1.1e-44 qacH U Small Multidrug Resistance protein
HPEHFLOH_01794 3e-116 hly S protein, hemolysin III
HPEHFLOH_01795 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HPEHFLOH_01796 2.7e-160 czcD P cation diffusion facilitator family transporter
HPEHFLOH_01797 2.6e-19
HPEHFLOH_01798 6.5e-96 tag 3.2.2.20 L glycosylase
HPEHFLOH_01799 6.8e-212 folP 2.5.1.15 H dihydropteroate synthase
HPEHFLOH_01800 6.7e-99 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HPEHFLOH_01801 6.5e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HPEHFLOH_01802 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HPEHFLOH_01803 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HPEHFLOH_01804 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPEHFLOH_01805 4.7e-83 cvpA S Colicin V production protein
HPEHFLOH_01806 1.9e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
HPEHFLOH_01807 1.9e-248 EGP Major facilitator Superfamily
HPEHFLOH_01809 7e-40
HPEHFLOH_01810 6.2e-96 V VanZ like family
HPEHFLOH_01811 1.9e-194 blaA6 V Beta-lactamase
HPEHFLOH_01812 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HPEHFLOH_01813 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPEHFLOH_01814 5.1e-53 yitW S Pfam:DUF59
HPEHFLOH_01815 1.7e-173 S Aldo keto reductase
HPEHFLOH_01816 3.3e-97 FG HIT domain
HPEHFLOH_01817 1.4e-37 S Bacteriocin-protection, YdeI or OmpD-Associated
HPEHFLOH_01818 5.3e-77
HPEHFLOH_01819 2e-120 E GDSL-like Lipase/Acylhydrolase family
HPEHFLOH_01820 1.5e-305 U Belongs to the BCCT transporter (TC 2.A.15) family
HPEHFLOH_01821 0.0 cadA P P-type ATPase
HPEHFLOH_01823 4.8e-125 yyaQ S YjbR
HPEHFLOH_01824 3.5e-219 S Uncharacterized protein conserved in bacteria (DUF2325)
HPEHFLOH_01825 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HPEHFLOH_01826 1.3e-196 frlB M SIS domain
HPEHFLOH_01827 8e-27 3.2.2.10 S Belongs to the LOG family
HPEHFLOH_01828 1.2e-255 nhaC C Na H antiporter NhaC
HPEHFLOH_01829 8.9e-251 cycA E Amino acid permease
HPEHFLOH_01830 1.8e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HPEHFLOH_01831 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HPEHFLOH_01832 4.8e-162 azoB GM NmrA-like family
HPEHFLOH_01833 4.1e-66 K Winged helix DNA-binding domain
HPEHFLOH_01834 7e-71 spx4 1.20.4.1 P ArsC family
HPEHFLOH_01835 1.7e-66 yeaO S Protein of unknown function, DUF488
HPEHFLOH_01836 4e-53
HPEHFLOH_01837 4.1e-214 mutY L A G-specific adenine glycosylase
HPEHFLOH_01838 1.9e-62
HPEHFLOH_01839 4.3e-86
HPEHFLOH_01840 1.2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
HPEHFLOH_01841 7e-56
HPEHFLOH_01842 2.1e-14
HPEHFLOH_01843 1.1e-115 GM NmrA-like family
HPEHFLOH_01844 1.3e-81 elaA S GNAT family
HPEHFLOH_01845 1.6e-158 EG EamA-like transporter family
HPEHFLOH_01846 1.8e-119 S membrane
HPEHFLOH_01847 6.8e-111 S VIT family
HPEHFLOH_01848 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HPEHFLOH_01849 0.0 copB 3.6.3.4 P P-type ATPase
HPEHFLOH_01850 9.4e-74 copR K Copper transport repressor CopY TcrY
HPEHFLOH_01851 2.1e-39
HPEHFLOH_01852 3.5e-73 S COG NOG18757 non supervised orthologous group
HPEHFLOH_01853 4.3e-248 lmrB EGP Major facilitator Superfamily
HPEHFLOH_01854 5e-24
HPEHFLOH_01855 4.2e-49
HPEHFLOH_01856 1.6e-64 ycgX S Protein of unknown function (DUF1398)
HPEHFLOH_01857 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HPEHFLOH_01858 5.9e-214 mdtG EGP Major facilitator Superfamily
HPEHFLOH_01859 1.2e-179 D Alpha beta
HPEHFLOH_01860 3.4e-77 M1-874 K Domain of unknown function (DUF1836)
HPEHFLOH_01861 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HPEHFLOH_01862 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HPEHFLOH_01863 2.1e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HPEHFLOH_01864 8.4e-152 ywkB S Membrane transport protein
HPEHFLOH_01865 5.2e-164 yvgN C Aldo keto reductase
HPEHFLOH_01866 9.2e-133 thrE S Putative threonine/serine exporter
HPEHFLOH_01867 7.5e-77 S Threonine/Serine exporter, ThrE
HPEHFLOH_01868 2.3e-43 S Protein of unknown function (DUF1093)
HPEHFLOH_01869 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HPEHFLOH_01870 1.7e-90 ymdB S Macro domain protein
HPEHFLOH_01871 5.8e-95 K transcriptional regulator
HPEHFLOH_01872 5.5e-50 yvlA
HPEHFLOH_01873 3e-160 ypuA S Protein of unknown function (DUF1002)
HPEHFLOH_01874 0.0
HPEHFLOH_01875 2.9e-185 S Bacterial protein of unknown function (DUF916)
HPEHFLOH_01876 1.7e-129 S WxL domain surface cell wall-binding
HPEHFLOH_01877 1.5e-135 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HPEHFLOH_01878 3.5e-88 K Winged helix DNA-binding domain
HPEHFLOH_01879 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
HPEHFLOH_01880 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HPEHFLOH_01881 1.8e-27
HPEHFLOH_01882 5e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HPEHFLOH_01883 9.7e-72 mltD CBM50 M PFAM NLP P60 protein
HPEHFLOH_01884 2.5e-53
HPEHFLOH_01885 4.2e-62
HPEHFLOH_01887 8.6e-13
HPEHFLOH_01888 2.8e-65 XK27_09885 V VanZ like family
HPEHFLOH_01890 1.3e-11 K Cro/C1-type HTH DNA-binding domain
HPEHFLOH_01891 4e-107
HPEHFLOH_01892 1.3e-53 S Uncharacterized protein conserved in bacteria (DUF2316)
HPEHFLOH_01893 6.2e-120 4.1.1.46 S Amidohydrolase
HPEHFLOH_01894 2.7e-100 K transcriptional regulator
HPEHFLOH_01895 1.2e-182 yfeX P Peroxidase
HPEHFLOH_01896 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HPEHFLOH_01897 2.4e-127 ydcF S Gram-negative-bacterium-type cell wall biogenesis
HPEHFLOH_01898 6.2e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HPEHFLOH_01899 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HPEHFLOH_01900 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPEHFLOH_01901 1.5e-55 txlA O Thioredoxin-like domain
HPEHFLOH_01902 9.5e-40 yrkD S Metal-sensitive transcriptional repressor
HPEHFLOH_01903 1.2e-18
HPEHFLOH_01904 2.5e-95 dps P Belongs to the Dps family
HPEHFLOH_01905 1.6e-32 copZ P Heavy-metal-associated domain
HPEHFLOH_01906 4.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HPEHFLOH_01907 0.0 pepO 3.4.24.71 O Peptidase family M13
HPEHFLOH_01908 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPEHFLOH_01909 1.3e-262 nox C NADH oxidase
HPEHFLOH_01910 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HPEHFLOH_01911 2.9e-152 S Cell surface protein
HPEHFLOH_01912 1.5e-118 S WxL domain surface cell wall-binding
HPEHFLOH_01913 2.3e-99 S WxL domain surface cell wall-binding
HPEHFLOH_01914 4.6e-45
HPEHFLOH_01915 5.4e-104 K Bacterial regulatory proteins, tetR family
HPEHFLOH_01916 1.5e-49
HPEHFLOH_01917 5.2e-248 S Putative metallopeptidase domain
HPEHFLOH_01918 1.6e-219 3.1.3.1 S associated with various cellular activities
HPEHFLOH_01919 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
HPEHFLOH_01920 0.0 ubiB S ABC1 family
HPEHFLOH_01921 1.3e-249 brnQ U Component of the transport system for branched-chain amino acids
HPEHFLOH_01922 0.0 lacS G Transporter
HPEHFLOH_01923 0.0 lacA 3.2.1.23 G -beta-galactosidase
HPEHFLOH_01924 3e-187 lacR K Transcriptional regulator
HPEHFLOH_01925 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPEHFLOH_01926 1.2e-230 mdtH P Sugar (and other) transporter
HPEHFLOH_01927 1.1e-302 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPEHFLOH_01928 9.5e-231 EGP Major facilitator Superfamily
HPEHFLOH_01929 2.2e-182 rhaR K helix_turn_helix, arabinose operon control protein
HPEHFLOH_01930 3.5e-111 fic D Fic/DOC family
HPEHFLOH_01931 1.6e-76 K Helix-turn-helix XRE-family like proteins
HPEHFLOH_01932 7.5e-183 galR K Transcriptional regulator
HPEHFLOH_01933 1.3e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HPEHFLOH_01934 8.9e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPEHFLOH_01935 7.8e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HPEHFLOH_01936 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HPEHFLOH_01937 1e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HPEHFLOH_01938 0.0 rafA 3.2.1.22 G alpha-galactosidase
HPEHFLOH_01939 0.0 lacS G Transporter
HPEHFLOH_01940 1.3e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HPEHFLOH_01941 1.1e-173 galR K Transcriptional regulator
HPEHFLOH_01942 6.3e-193 C Aldo keto reductase family protein
HPEHFLOH_01943 2.4e-65 S pyridoxamine 5-phosphate
HPEHFLOH_01944 0.0 1.3.5.4 C FAD binding domain
HPEHFLOH_01945 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPEHFLOH_01946 1.7e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HPEHFLOH_01947 2.5e-166 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPEHFLOH_01948 9.2e-175 K Transcriptional regulator, LysR family
HPEHFLOH_01949 1.2e-219 ydiN EGP Major Facilitator Superfamily
HPEHFLOH_01950 5e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPEHFLOH_01951 9.4e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPEHFLOH_01952 1e-156 IQ Enoyl-(Acyl carrier protein) reductase
HPEHFLOH_01953 2.1e-165 G Xylose isomerase-like TIM barrel
HPEHFLOH_01954 4.7e-168 K Transcriptional regulator, LysR family
HPEHFLOH_01955 5.7e-201 EGP Major Facilitator Superfamily
HPEHFLOH_01956 7.6e-64
HPEHFLOH_01957 6.9e-155 estA S Putative esterase
HPEHFLOH_01958 6.2e-134 K UTRA domain
HPEHFLOH_01959 2.4e-248 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEHFLOH_01960 1e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPEHFLOH_01961 2.2e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HPEHFLOH_01962 1.1e-211 S Bacterial protein of unknown function (DUF871)
HPEHFLOH_01963 3.2e-117 K helix_turn_helix, arabinose operon control protein
HPEHFLOH_01964 8.2e-218 2.7.13.3 T Histidine kinase
HPEHFLOH_01965 1.4e-309 1.3.99.33 C FAD binding domain
HPEHFLOH_01966 7.7e-91 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HPEHFLOH_01967 2.7e-256 mngB 3.2.1.170 GH38 G Alpha mannosidase, middle domain
HPEHFLOH_01968 9.9e-224 hrsA 2.7.1.195, 2.7.1.202 GT Phosphotransferase System
HPEHFLOH_01969 2.5e-50 K Helix-turn-helix domain, rpiR family
HPEHFLOH_01970 2.1e-72 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPEHFLOH_01971 5.2e-209 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPEHFLOH_01972 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPEHFLOH_01973 1.3e-117 licT K CAT RNA binding domain
HPEHFLOH_01974 0.0 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPEHFLOH_01975 1e-223 malY 4.4.1.8 E Aminotransferase class I and II
HPEHFLOH_01976 1e-268 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HPEHFLOH_01977 3.3e-74 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPEHFLOH_01978 3.7e-79 ptsG 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPEHFLOH_01979 1.6e-146 yleF K Helix-turn-helix domain, rpiR family
HPEHFLOH_01980 7.1e-270 sacX 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPEHFLOH_01981 5.4e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPEHFLOH_01982 5.1e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HPEHFLOH_01983 7.5e-293 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPEHFLOH_01984 1.9e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPEHFLOH_01985 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPEHFLOH_01986 3.8e-159 licT K CAT RNA binding domain
HPEHFLOH_01987 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
HPEHFLOH_01988 2.1e-174 K Transcriptional regulator, LacI family
HPEHFLOH_01989 6.1e-271 G Major Facilitator
HPEHFLOH_01990 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HPEHFLOH_01992 1.1e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPEHFLOH_01993 1.5e-144 yxeH S hydrolase
HPEHFLOH_01994 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPEHFLOH_01995 2.2e-114 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HPEHFLOH_01996 1.7e-238 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HPEHFLOH_01997 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
HPEHFLOH_01998 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPEHFLOH_01999 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPEHFLOH_02000 1.8e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
HPEHFLOH_02001 8.6e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HPEHFLOH_02002 5.5e-231 gatC G PTS system sugar-specific permease component
HPEHFLOH_02003 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HPEHFLOH_02004 5.6e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPEHFLOH_02005 7e-112 K DeoR C terminal sensor domain
HPEHFLOH_02006 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HPEHFLOH_02007 7.4e-136 K Helix-turn-helix domain, rpiR family
HPEHFLOH_02008 3.7e-72 yueI S Protein of unknown function (DUF1694)
HPEHFLOH_02009 2.9e-164 I alpha/beta hydrolase fold
HPEHFLOH_02010 7.5e-160 I alpha/beta hydrolase fold
HPEHFLOH_02011 2.6e-272 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HPEHFLOH_02012 1.5e-206 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HPEHFLOH_02013 1.9e-135 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
HPEHFLOH_02014 5.2e-156 nanK GK ROK family
HPEHFLOH_02015 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HPEHFLOH_02016 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HPEHFLOH_02017 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
HPEHFLOH_02018 4.2e-70 S Pyrimidine dimer DNA glycosylase
HPEHFLOH_02019 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HPEHFLOH_02020 3.6e-11
HPEHFLOH_02021 9e-13 ytgB S Transglycosylase associated protein
HPEHFLOH_02022 3.5e-290 katA 1.11.1.6 C Belongs to the catalase family
HPEHFLOH_02023 4.9e-78 yneH 1.20.4.1 K ArsC family
HPEHFLOH_02024 7.4e-135 K LytTr DNA-binding domain
HPEHFLOH_02025 8.7e-160 2.7.13.3 T GHKL domain
HPEHFLOH_02026 1.8e-12
HPEHFLOH_02027 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HPEHFLOH_02028 3.3e-251 clpL O C-terminal, D2-small domain, of ClpB protein
HPEHFLOH_02030 1.7e-48 5.3.3.19 S Cupin 2, conserved barrel domain protein
HPEHFLOH_02031 2.5e-53 S Cupin domain
HPEHFLOH_02032 7.8e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HPEHFLOH_02033 4.7e-194 ybiR P Citrate transporter
HPEHFLOH_02034 1.6e-151 pnuC H nicotinamide mononucleotide transporter
HPEHFLOH_02035 1.1e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPEHFLOH_02036 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPEHFLOH_02037 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
HPEHFLOH_02038 8.7e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HPEHFLOH_02039 3.4e-288 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPEHFLOH_02040 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HPEHFLOH_02041 0.0 pacL 3.6.3.8 P P-type ATPase
HPEHFLOH_02042 7.5e-71
HPEHFLOH_02043 0.0 yhgF K Tex-like protein N-terminal domain protein
HPEHFLOH_02044 9.8e-82 ydcK S Belongs to the SprT family
HPEHFLOH_02045 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HPEHFLOH_02046 3.8e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPEHFLOH_02048 7.7e-54 sip L Belongs to the 'phage' integrase family
HPEHFLOH_02051 1.2e-13
HPEHFLOH_02052 4.8e-17 E Pfam:DUF955
HPEHFLOH_02053 1.6e-29 yvaO K Helix-turn-helix XRE-family like proteins
HPEHFLOH_02054 7.9e-14 K Helix-turn-helix
HPEHFLOH_02055 1.7e-92 K ORF6N domain
HPEHFLOH_02062 4e-41 S Siphovirus Gp157
HPEHFLOH_02063 1.5e-162 S helicase activity
HPEHFLOH_02064 2.4e-12 L HNH endonuclease
HPEHFLOH_02065 1.3e-72 L AAA domain
HPEHFLOH_02066 2.2e-26
HPEHFLOH_02067 1.2e-77 S Bifunctional DNA primase/polymerase, N-terminal
HPEHFLOH_02068 4.5e-07 S Virulence-associated protein E
HPEHFLOH_02069 1.5e-117 S Virulence-associated protein E
HPEHFLOH_02070 8.4e-38 S VRR_NUC
HPEHFLOH_02071 4.2e-13
HPEHFLOH_02072 3.4e-73 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HPEHFLOH_02074 3e-10
HPEHFLOH_02076 2.9e-22
HPEHFLOH_02081 6.2e-13
HPEHFLOH_02082 9.7e-175 S Terminase
HPEHFLOH_02083 3.6e-104 S Phage portal protein
HPEHFLOH_02084 2.4e-56 clpP 3.4.21.92 OU Clp protease
HPEHFLOH_02085 1.1e-113 S Phage capsid family
HPEHFLOH_02086 9.8e-17
HPEHFLOH_02087 4.7e-24
HPEHFLOH_02088 1.7e-32
HPEHFLOH_02089 1.4e-21
HPEHFLOH_02090 1.8e-38 S Phage tail tube protein
HPEHFLOH_02092 3.8e-141 M Phage tail tape measure protein TP901
HPEHFLOH_02093 1.8e-33 S Phage tail protein
HPEHFLOH_02094 4.1e-141 sidC GT2,GT4 LM DNA recombination
HPEHFLOH_02095 2.1e-71 S Protein of unknown function (DUF1617)
HPEHFLOH_02097 1.4e-39
HPEHFLOH_02100 5e-80 ps461 M Glycosyl hydrolases family 25
HPEHFLOH_02101 1.1e-152 G Peptidase_C39 like family
HPEHFLOH_02102 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HPEHFLOH_02103 3.4e-133 manY G PTS system
HPEHFLOH_02104 4.4e-169 manN G system, mannose fructose sorbose family IID component
HPEHFLOH_02105 4.7e-64 S Domain of unknown function (DUF956)
HPEHFLOH_02106 0.0 levR K Sigma-54 interaction domain
HPEHFLOH_02107 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
HPEHFLOH_02108 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
HPEHFLOH_02109 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPEHFLOH_02110 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
HPEHFLOH_02111 1.5e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
HPEHFLOH_02112 1.8e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HPEHFLOH_02113 7.7e-135 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HPEHFLOH_02114 2.4e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPEHFLOH_02115 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HPEHFLOH_02116 1.7e-177 EG EamA-like transporter family
HPEHFLOH_02117 4.7e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPEHFLOH_02118 1.7e-111 zmp2 O Zinc-dependent metalloprotease
HPEHFLOH_02119 2.8e-257 pepC 3.4.22.40 E Peptidase C1-like family
HPEHFLOH_02120 4.1e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPEHFLOH_02121 1.6e-51 HA62_12640 S GCN5-related N-acetyl-transferase
HPEHFLOH_02122 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HPEHFLOH_02123 1.7e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPEHFLOH_02124 3.7e-205 yacL S domain protein
HPEHFLOH_02125 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPEHFLOH_02126 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPEHFLOH_02127 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HPEHFLOH_02128 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPEHFLOH_02129 1.2e-97 yacP S YacP-like NYN domain
HPEHFLOH_02130 9.1e-101 sigH K Sigma-70 region 2
HPEHFLOH_02131 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HPEHFLOH_02132 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPEHFLOH_02133 1.4e-98 nusG K Participates in transcription elongation, termination and antitermination
HPEHFLOH_02134 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
HPEHFLOH_02135 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPEHFLOH_02136 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPEHFLOH_02137 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPEHFLOH_02138 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPEHFLOH_02139 9.3e-178 F DNA/RNA non-specific endonuclease
HPEHFLOH_02140 1.2e-38 L nuclease
HPEHFLOH_02141 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPEHFLOH_02142 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
HPEHFLOH_02143 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPEHFLOH_02144 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPEHFLOH_02145 6.5e-37 nrdH O Glutaredoxin
HPEHFLOH_02146 2.2e-108 rsmC 2.1.1.172 J Methyltransferase
HPEHFLOH_02147 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPEHFLOH_02148 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPEHFLOH_02149 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HPEHFLOH_02150 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPEHFLOH_02151 2.2e-38 yaaL S Protein of unknown function (DUF2508)
HPEHFLOH_02152 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPEHFLOH_02153 9.1e-50 yaaQ S Cyclic-di-AMP receptor
HPEHFLOH_02154 3.3e-186 holB 2.7.7.7 L DNA polymerase III
HPEHFLOH_02155 1e-57 yabA L Involved in initiation control of chromosome replication
HPEHFLOH_02156 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPEHFLOH_02157 2.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
HPEHFLOH_02158 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPEHFLOH_02159 1.5e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HPEHFLOH_02160 1.4e-144 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
HPEHFLOH_02161 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
HPEHFLOH_02162 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
HPEHFLOH_02163 2.8e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HPEHFLOH_02164 5.1e-190 phnD P Phosphonate ABC transporter
HPEHFLOH_02165 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HPEHFLOH_02166 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HPEHFLOH_02167 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HPEHFLOH_02168 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPEHFLOH_02169 1.1e-307 uup S ABC transporter, ATP-binding protein
HPEHFLOH_02170 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HPEHFLOH_02171 6.1e-109 ydiL S CAAX protease self-immunity
HPEHFLOH_02172 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPEHFLOH_02173 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPEHFLOH_02174 0.0 ydaO E amino acid
HPEHFLOH_02175 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
HPEHFLOH_02176 4.3e-145 pstS P Phosphate
HPEHFLOH_02177 1.7e-114 yvyE 3.4.13.9 S YigZ family
HPEHFLOH_02178 1.5e-258 comFA L Helicase C-terminal domain protein
HPEHFLOH_02179 7.5e-126 comFC S Competence protein
HPEHFLOH_02180 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPEHFLOH_02181 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPEHFLOH_02182 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPEHFLOH_02183 2.1e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HPEHFLOH_02184 1.5e-132 K response regulator
HPEHFLOH_02185 1.1e-246 phoR 2.7.13.3 T Histidine kinase
HPEHFLOH_02186 2.1e-149 pstS P Phosphate
HPEHFLOH_02187 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
HPEHFLOH_02188 1.5e-155 pstA P Phosphate transport system permease protein PstA
HPEHFLOH_02189 4.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPEHFLOH_02190 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPEHFLOH_02191 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
HPEHFLOH_02192 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
HPEHFLOH_02193 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HPEHFLOH_02194 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HPEHFLOH_02195 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPEHFLOH_02196 7.2e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HPEHFLOH_02197 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HPEHFLOH_02198 4.1e-124 yliE T Putative diguanylate phosphodiesterase
HPEHFLOH_02199 5.1e-270 nox C NADH oxidase
HPEHFLOH_02200 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPEHFLOH_02201 1.3e-108 yviA S Protein of unknown function (DUF421)
HPEHFLOH_02202 3.3e-61 S Protein of unknown function (DUF3290)
HPEHFLOH_02203 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HPEHFLOH_02205 4e-201 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HPEHFLOH_02206 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPEHFLOH_02207 8.7e-72 K Transcriptional regulator
HPEHFLOH_02208 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPEHFLOH_02209 9.3e-71 yueI S Protein of unknown function (DUF1694)
HPEHFLOH_02210 1.7e-125 S Membrane
HPEHFLOH_02211 4.6e-165 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HPEHFLOH_02212 1.3e-256 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HPEHFLOH_02213 1.4e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HPEHFLOH_02214 1.8e-286 rhaB 2.7.1.12, 2.7.1.16, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HPEHFLOH_02215 1.2e-241 iolF EGP Major facilitator Superfamily
HPEHFLOH_02216 3.8e-179 rhaR K helix_turn_helix, arabinose operon control protein
HPEHFLOH_02217 2.3e-139 K DeoR C terminal sensor domain
HPEHFLOH_02218 4.2e-80 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HPEHFLOH_02219 7.3e-52 sgcB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HPEHFLOH_02220 1.1e-249 pts36C G PTS system sugar-specific permease component
HPEHFLOH_02222 1.2e-134 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HPEHFLOH_02223 2.4e-259 iolT EGP Major facilitator Superfamily
HPEHFLOH_02224 8.6e-198 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HPEHFLOH_02225 7.6e-202 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HPEHFLOH_02226 2.5e-177 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HPEHFLOH_02227 4.7e-196 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HPEHFLOH_02228 4.5e-269 iolT EGP Major facilitator Superfamily
HPEHFLOH_02229 4.5e-191 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HPEHFLOH_02230 7.8e-82 S Haem-degrading
HPEHFLOH_02231 2.1e-171 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
HPEHFLOH_02232 1.5e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HPEHFLOH_02233 1.2e-45 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HPEHFLOH_02234 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HPEHFLOH_02235 1.1e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HPEHFLOH_02236 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
HPEHFLOH_02237 4.3e-86 gutM K Glucitol operon activator protein (GutM)
HPEHFLOH_02238 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HPEHFLOH_02239 3.8e-145 IQ NAD dependent epimerase/dehydratase family
HPEHFLOH_02240 2.7e-160 rbsU U ribose uptake protein RbsU
HPEHFLOH_02241 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HPEHFLOH_02242 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPEHFLOH_02243 5.2e-188 rbsR K helix_turn _helix lactose operon repressor
HPEHFLOH_02245 1.7e-08
HPEHFLOH_02246 6.2e-54
HPEHFLOH_02247 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HPEHFLOH_02248 2.7e-79 T Universal stress protein family
HPEHFLOH_02249 2.2e-99 padR K Virulence activator alpha C-term
HPEHFLOH_02250 1.6e-102 padC Q Phenolic acid decarboxylase
HPEHFLOH_02251 6.7e-142 tesE Q hydratase
HPEHFLOH_02252 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
HPEHFLOH_02253 2.8e-157 degV S DegV family
HPEHFLOH_02254 8.4e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
HPEHFLOH_02255 1.5e-255 pepC 3.4.22.40 E aminopeptidase
HPEHFLOH_02257 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPEHFLOH_02258 1.2e-301
HPEHFLOH_02260 8e-159 S Bacterial protein of unknown function (DUF916)
HPEHFLOH_02261 6.9e-93 S Cell surface protein
HPEHFLOH_02262 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPEHFLOH_02263 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPEHFLOH_02264 9.1e-109 jag S R3H domain protein
HPEHFLOH_02265 1.3e-237 Q Imidazolonepropionase and related amidohydrolases
HPEHFLOH_02266 1e-309 E ABC transporter, substratebinding protein
HPEHFLOH_02267 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HPEHFLOH_02268 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPEHFLOH_02269 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPEHFLOH_02270 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPEHFLOH_02271 5e-37 yaaA S S4 domain protein YaaA
HPEHFLOH_02272 7.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPEHFLOH_02273 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPEHFLOH_02274 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPEHFLOH_02275 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HPEHFLOH_02276 1e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HPEHFLOH_02277 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPEHFLOH_02278 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HPEHFLOH_02279 1.4e-67 rplI J Binds to the 23S rRNA
HPEHFLOH_02280 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HPEHFLOH_02281 8.8e-226 yttB EGP Major facilitator Superfamily
HPEHFLOH_02282 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPEHFLOH_02283 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPEHFLOH_02285 6.1e-275 E ABC transporter, substratebinding protein
HPEHFLOH_02286 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPEHFLOH_02287 7.2e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPEHFLOH_02288 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HPEHFLOH_02289 6.8e-278 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HPEHFLOH_02290 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HPEHFLOH_02291 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HPEHFLOH_02293 4.5e-143 S haloacid dehalogenase-like hydrolase
HPEHFLOH_02294 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HPEHFLOH_02295 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HPEHFLOH_02296 2e-32 S Pyridoxamine 5'-phosphate oxidase
HPEHFLOH_02297 8.3e-20 S Pyridoxamine 5'-phosphate oxidase
HPEHFLOH_02298 1.6e-31 cspA K Cold shock protein domain
HPEHFLOH_02299 1.7e-37
HPEHFLOH_02301 6.2e-131 K response regulator
HPEHFLOH_02302 0.0 vicK 2.7.13.3 T Histidine kinase
HPEHFLOH_02303 1.2e-244 yycH S YycH protein
HPEHFLOH_02304 2.2e-151 yycI S YycH protein
HPEHFLOH_02305 8.9e-158 vicX 3.1.26.11 S domain protein
HPEHFLOH_02306 5.2e-173 htrA 3.4.21.107 O serine protease
HPEHFLOH_02307 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPEHFLOH_02308 9.9e-95 K Bacterial regulatory proteins, tetR family
HPEHFLOH_02309 4.9e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
HPEHFLOH_02310 1.5e-167 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HPEHFLOH_02311 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HPEHFLOH_02312 1.7e-122 pnb C nitroreductase
HPEHFLOH_02313 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HPEHFLOH_02314 1.8e-116 S Elongation factor G-binding protein, N-terminal
HPEHFLOH_02315 8.3e-134 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
HPEHFLOH_02316 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
HPEHFLOH_02317 3.5e-258 P Sodium:sulfate symporter transmembrane region
HPEHFLOH_02318 1.3e-157 K LysR family
HPEHFLOH_02319 1e-72 C FMN binding
HPEHFLOH_02320 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPEHFLOH_02321 2.3e-164 ptlF S KR domain
HPEHFLOH_02322 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HPEHFLOH_02323 2.4e-121 drgA C Nitroreductase family
HPEHFLOH_02324 1.3e-290 QT PucR C-terminal helix-turn-helix domain
HPEHFLOH_02325 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HPEHFLOH_02326 5.1e-195 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPEHFLOH_02327 1.4e-248 yjjP S Putative threonine/serine exporter
HPEHFLOH_02328 2.8e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
HPEHFLOH_02329 1.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
HPEHFLOH_02330 1.1e-80 6.3.3.2 S ASCH
HPEHFLOH_02331 5.5e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HPEHFLOH_02332 5.5e-172 yobV1 K WYL domain
HPEHFLOH_02333 1.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HPEHFLOH_02334 0.0 tetP J elongation factor G
HPEHFLOH_02335 1.1e-124 S Protein of unknown function
HPEHFLOH_02336 1.5e-150 EG EamA-like transporter family
HPEHFLOH_02337 2.2e-87 MA20_25245 K FR47-like protein
HPEHFLOH_02338 2e-126 hchA S DJ-1/PfpI family
HPEHFLOH_02339 2.7e-180 1.1.1.1 C nadph quinone reductase
HPEHFLOH_02340 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPEHFLOH_02341 2.3e-235 mepA V MATE efflux family protein
HPEHFLOH_02342 1.1e-166 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HPEHFLOH_02343 1.3e-139 S Belongs to the UPF0246 family
HPEHFLOH_02344 6e-76
HPEHFLOH_02345 1.5e-280 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HPEHFLOH_02346 9.1e-141
HPEHFLOH_02348 1.9e-118 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HPEHFLOH_02349 4.8e-40
HPEHFLOH_02350 7.8e-129 cbiO P ABC transporter
HPEHFLOH_02351 2.6e-149 P Cobalt transport protein
HPEHFLOH_02352 4.8e-182 nikMN P PDGLE domain
HPEHFLOH_02353 4.2e-121 K Crp-like helix-turn-helix domain
HPEHFLOH_02354 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HPEHFLOH_02355 5.3e-122 larB S AIR carboxylase
HPEHFLOH_02356 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HPEHFLOH_02357 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
HPEHFLOH_02358 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPEHFLOH_02359 4.1e-150 larE S NAD synthase
HPEHFLOH_02360 5.1e-176 1.6.5.5 C Zinc-binding dehydrogenase
HPEHFLOH_02361 2.2e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HPEHFLOH_02362 9.1e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HPEHFLOH_02363 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HPEHFLOH_02364 3.8e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HPEHFLOH_02365 5.1e-136 S peptidase C26
HPEHFLOH_02366 3.6e-304 L HIRAN domain
HPEHFLOH_02367 3.4e-85 F NUDIX domain
HPEHFLOH_02368 2.6e-250 yifK E Amino acid permease
HPEHFLOH_02369 5.2e-122
HPEHFLOH_02370 3.3e-149 ydjP I Alpha/beta hydrolase family
HPEHFLOH_02371 0.0 pacL1 P P-type ATPase
HPEHFLOH_02372 1.6e-28 KT PspC domain
HPEHFLOH_02373 6.7e-110 S NADPH-dependent FMN reductase
HPEHFLOH_02374 1.2e-74 papX3 K Transcriptional regulator
HPEHFLOH_02375 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
HPEHFLOH_02376 4.9e-81 S Protein of unknown function (DUF3021)
HPEHFLOH_02377 3e-75 K LytTr DNA-binding domain
HPEHFLOH_02378 4.7e-227 mdtG EGP Major facilitator Superfamily
HPEHFLOH_02379 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPEHFLOH_02380 3.1e-215 yeaN P Transporter, major facilitator family protein
HPEHFLOH_02382 5.8e-160 S reductase
HPEHFLOH_02383 1.2e-165 1.1.1.65 C Aldo keto reductase
HPEHFLOH_02384 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
HPEHFLOH_02385 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HPEHFLOH_02386 5e-52
HPEHFLOH_02387 7.5e-259
HPEHFLOH_02388 4e-209 C Oxidoreductase
HPEHFLOH_02389 7.1e-150 cbiQ P cobalt transport
HPEHFLOH_02390 0.0 ykoD P ABC transporter, ATP-binding protein
HPEHFLOH_02391 2.5e-98 S UPF0397 protein
HPEHFLOH_02392 1.6e-129 K UbiC transcription regulator-associated domain protein
HPEHFLOH_02393 8.3e-54 K Transcriptional regulator PadR-like family
HPEHFLOH_02394 4.3e-141
HPEHFLOH_02395 2e-149
HPEHFLOH_02396 9.1e-89
HPEHFLOH_02397 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HPEHFLOH_02398 7.4e-169 yjjC V ABC transporter
HPEHFLOH_02399 4.3e-297 M Exporter of polyketide antibiotics
HPEHFLOH_02400 1.1e-116 K Transcriptional regulator
HPEHFLOH_02401 3.8e-274 C Electron transfer flavoprotein FAD-binding domain
HPEHFLOH_02402 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
HPEHFLOH_02404 1.1e-92 K Bacterial regulatory proteins, tetR family
HPEHFLOH_02405 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HPEHFLOH_02406 7.3e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HPEHFLOH_02407 1.9e-101 dhaL 2.7.1.121 S Dak2
HPEHFLOH_02408 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
HPEHFLOH_02409 8.6e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPEHFLOH_02410 1e-190 malR K Transcriptional regulator, LacI family
HPEHFLOH_02411 2e-180 yvdE K helix_turn _helix lactose operon repressor
HPEHFLOH_02412 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HPEHFLOH_02413 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
HPEHFLOH_02414 8.4e-227 malC P Binding-protein-dependent transport system inner membrane component
HPEHFLOH_02415 1.4e-161 malD P ABC transporter permease
HPEHFLOH_02416 5.3e-150 malA S maltodextrose utilization protein MalA
HPEHFLOH_02417 5e-259 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HPEHFLOH_02418 3.4e-208 msmK P Belongs to the ABC transporter superfamily
HPEHFLOH_02419 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HPEHFLOH_02420 0.0 3.2.1.96 G Glycosyl hydrolase family 85
HPEHFLOH_02421 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
HPEHFLOH_02422 1.8e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HPEHFLOH_02423 0.0 rafA 3.2.1.22 G alpha-galactosidase
HPEHFLOH_02424 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HPEHFLOH_02425 1.4e-305 scrB 3.2.1.26 GH32 G invertase
HPEHFLOH_02426 9.1e-173 scrR K Transcriptional regulator, LacI family
HPEHFLOH_02427 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HPEHFLOH_02428 6.5e-165 3.5.1.10 C nadph quinone reductase
HPEHFLOH_02429 1.1e-217 nhaC C Na H antiporter NhaC
HPEHFLOH_02430 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HPEHFLOH_02431 2.9e-165 mleR K LysR substrate binding domain
HPEHFLOH_02432 0.0 3.6.4.13 M domain protein
HPEHFLOH_02434 2.1e-157 hipB K Helix-turn-helix
HPEHFLOH_02435 0.0 oppA E ABC transporter, substratebinding protein
HPEHFLOH_02436 3.5e-310 oppA E ABC transporter, substratebinding protein
HPEHFLOH_02437 1e-78 yiaC K Acetyltransferase (GNAT) domain
HPEHFLOH_02438 6.7e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPEHFLOH_02439 6e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HPEHFLOH_02440 3e-113 pgm1 G phosphoglycerate mutase
HPEHFLOH_02441 1e-179 yghZ C Aldo keto reductase family protein
HPEHFLOH_02442 4.9e-34
HPEHFLOH_02443 1.3e-60 S Domain of unknown function (DU1801)
HPEHFLOH_02444 5.4e-161 FbpA K Domain of unknown function (DUF814)
HPEHFLOH_02445 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPEHFLOH_02447 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPEHFLOH_02448 1.9e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPEHFLOH_02449 4.4e-259 S ATPases associated with a variety of cellular activities
HPEHFLOH_02450 3.1e-116 P cobalt transport
HPEHFLOH_02451 1.4e-259 P ABC transporter
HPEHFLOH_02452 3.1e-101 S ABC transporter permease
HPEHFLOH_02453 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HPEHFLOH_02454 1.4e-158 dkgB S reductase
HPEHFLOH_02455 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPEHFLOH_02456 1e-69
HPEHFLOH_02457 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPEHFLOH_02459 6.3e-276 pipD E Dipeptidase
HPEHFLOH_02460 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HPEHFLOH_02461 0.0 mtlR K Mga helix-turn-helix domain
HPEHFLOH_02462 3.9e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEHFLOH_02463 9.5e-222 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HPEHFLOH_02464 2.1e-73
HPEHFLOH_02465 6.2e-57 trxA1 O Belongs to the thioredoxin family
HPEHFLOH_02466 2.5e-50
HPEHFLOH_02467 6.6e-96
HPEHFLOH_02468 2e-62
HPEHFLOH_02469 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
HPEHFLOH_02470 7.6e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
HPEHFLOH_02471 3.5e-97 yieF S NADPH-dependent FMN reductase
HPEHFLOH_02472 7.2e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HPEHFLOH_02473 9.8e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HPEHFLOH_02474 1.9e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HPEHFLOH_02475 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
HPEHFLOH_02476 4.3e-141 pnuC H nicotinamide mononucleotide transporter
HPEHFLOH_02477 7.3e-43 S Protein of unknown function (DUF2089)
HPEHFLOH_02478 2.2e-42
HPEHFLOH_02479 3.5e-129 treR K UTRA
HPEHFLOH_02480 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HPEHFLOH_02481 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HPEHFLOH_02482 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HPEHFLOH_02483 1.4e-144
HPEHFLOH_02484 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HPEHFLOH_02485 1.6e-235 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
HPEHFLOH_02486 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HPEHFLOH_02487 3.5e-144 S Psort location CytoplasmicMembrane, score
HPEHFLOH_02488 1.4e-13 S Psort location CytoplasmicMembrane, score
HPEHFLOH_02489 7.7e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HPEHFLOH_02490 1e-69
HPEHFLOH_02492 1.6e-28 M Glycosyl hydrolases family 25
HPEHFLOH_02493 4e-34 M Glycosyl hydrolases family 25
HPEHFLOH_02494 1.8e-72 K Transcriptional regulator
HPEHFLOH_02495 4.3e-121 K Bacterial regulatory proteins, tetR family
HPEHFLOH_02496 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HPEHFLOH_02497 5.5e-118
HPEHFLOH_02498 5.2e-42
HPEHFLOH_02499 1e-40
HPEHFLOH_02500 8.2e-252 ydiC1 EGP Major facilitator Superfamily
HPEHFLOH_02501 9.5e-65 K helix_turn_helix, mercury resistance
HPEHFLOH_02502 2.3e-251 T PhoQ Sensor
HPEHFLOH_02503 1.3e-128 K Transcriptional regulatory protein, C terminal
HPEHFLOH_02504 1.8e-49
HPEHFLOH_02505 2.1e-129 yidA K Helix-turn-helix domain, rpiR family
HPEHFLOH_02506 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEHFLOH_02507 9.9e-57
HPEHFLOH_02508 2.1e-41
HPEHFLOH_02509 1.4e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPEHFLOH_02510 2.9e-85 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HPEHFLOH_02511 3.9e-26 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HPEHFLOH_02512 1.6e-106 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HPEHFLOH_02513 1.3e-47
HPEHFLOH_02514 2.7e-123 2.7.6.5 S RelA SpoT domain protein
HPEHFLOH_02515 3.1e-104 K transcriptional regulator
HPEHFLOH_02516 0.0 ydgH S MMPL family
HPEHFLOH_02517 1e-107 tag 3.2.2.20 L glycosylase
HPEHFLOH_02518 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HPEHFLOH_02519 6.5e-183 yclI V MacB-like periplasmic core domain
HPEHFLOH_02520 7.1e-121 yclH V ABC transporter
HPEHFLOH_02521 2.5e-114 V CAAX protease self-immunity
HPEHFLOH_02522 1.3e-120 S CAAX protease self-immunity
HPEHFLOH_02523 1.7e-52 M Lysin motif
HPEHFLOH_02524 1.8e-52 lytE M LysM domain protein
HPEHFLOH_02525 7.4e-67 gcvH E Glycine cleavage H-protein
HPEHFLOH_02526 2.8e-176 sepS16B
HPEHFLOH_02527 3.7e-131
HPEHFLOH_02528 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HPEHFLOH_02529 2.2e-55
HPEHFLOH_02530 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPEHFLOH_02531 6.5e-78 elaA S GNAT family
HPEHFLOH_02532 1.7e-75 K Transcriptional regulator
HPEHFLOH_02533 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
HPEHFLOH_02534 4.3e-40
HPEHFLOH_02535 4e-206 potD P ABC transporter
HPEHFLOH_02536 3.4e-141 potC P ABC transporter permease
HPEHFLOH_02537 2e-149 potB P ABC transporter permease
HPEHFLOH_02538 1.2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPEHFLOH_02539 5e-96 puuR K Cupin domain
HPEHFLOH_02540 1.1e-83 6.3.3.2 S ASCH
HPEHFLOH_02541 1e-84 K GNAT family
HPEHFLOH_02542 1.8e-90 K acetyltransferase
HPEHFLOH_02543 8.1e-22
HPEHFLOH_02544 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HPEHFLOH_02545 2e-163 ytrB V ABC transporter
HPEHFLOH_02546 4.9e-190
HPEHFLOH_02547 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HPEHFLOH_02548 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HPEHFLOH_02550 3.4e-239 xylP1 G MFS/sugar transport protein
HPEHFLOH_02551 3e-122 qmcA O prohibitin homologues
HPEHFLOH_02552 1.5e-29
HPEHFLOH_02553 5e-281 pipD E Dipeptidase
HPEHFLOH_02554 3e-40
HPEHFLOH_02555 6.8e-96 bioY S BioY family
HPEHFLOH_02556 4.2e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPEHFLOH_02557 2.8e-60 S CHY zinc finger
HPEHFLOH_02558 2.2e-111 metQ P NLPA lipoprotein
HPEHFLOH_02559 8.7e-126 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPEHFLOH_02560 1.1e-86 metI U Binding-protein-dependent transport system inner membrane component
HPEHFLOH_02561 2.9e-147 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPEHFLOH_02562 2.2e-221 mtnE 2.6.1.83 E Aminotransferase
HPEHFLOH_02563 3.8e-218
HPEHFLOH_02564 3.5e-154 tagG U Transport permease protein
HPEHFLOH_02565 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HPEHFLOH_02566 8.4e-44
HPEHFLOH_02567 3.9e-93 K Transcriptional regulator PadR-like family
HPEHFLOH_02568 8.7e-257 P Major Facilitator Superfamily
HPEHFLOH_02569 4.7e-241 amtB P ammonium transporter
HPEHFLOH_02570 5.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HPEHFLOH_02571 3.7e-44
HPEHFLOH_02572 5.3e-101 zmp1 O Zinc-dependent metalloprotease
HPEHFLOH_02573 1.8e-119 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HPEHFLOH_02574 5.4e-310 mco Q Multicopper oxidase
HPEHFLOH_02575 1.1e-54 ypaA S Protein of unknown function (DUF1304)
HPEHFLOH_02576 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
HPEHFLOH_02577 4.7e-232 flhF N Uncharacterized conserved protein (DUF2075)
HPEHFLOH_02578 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HPEHFLOH_02579 7.1e-80
HPEHFLOH_02580 5.9e-60 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPEHFLOH_02581 4.5e-174 rihC 3.2.2.1 F Nucleoside
HPEHFLOH_02582 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPEHFLOH_02583 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
HPEHFLOH_02584 4e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HPEHFLOH_02585 9.9e-180 proV E ABC transporter, ATP-binding protein
HPEHFLOH_02586 1.7e-254 gshR 1.8.1.7 C Glutathione reductase
HPEHFLOH_02587 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HPEHFLOH_02588 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HPEHFLOH_02589 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPEHFLOH_02590 2.9e-241 M domain protein
HPEHFLOH_02591 5e-52 U domain, Protein
HPEHFLOH_02592 4.4e-25 S Immunity protein 74
HPEHFLOH_02593 9.2e-127
HPEHFLOH_02594 2.8e-28
HPEHFLOH_02595 1.1e-65
HPEHFLOH_02596 2.1e-67 S Immunity protein 63
HPEHFLOH_02597 2.8e-23
HPEHFLOH_02598 1.9e-38
HPEHFLOH_02599 6.2e-119 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HPEHFLOH_02600 5.3e-196 uhpT EGP Major facilitator Superfamily
HPEHFLOH_02601 1e-48 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
HPEHFLOH_02602 5.3e-83 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
HPEHFLOH_02603 4.3e-166 K Transcriptional regulator
HPEHFLOH_02604 1.4e-150 S hydrolase
HPEHFLOH_02605 3.9e-254 brnQ U Component of the transport system for branched-chain amino acids
HPEHFLOH_02606 2.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HPEHFLOH_02608 4.5e-115
HPEHFLOH_02610 2.4e-69 S CAAX protease self-immunity
HPEHFLOH_02611 6.7e-119 ypbD S CAAX protease self-immunity
HPEHFLOH_02612 8.1e-112 V CAAX protease self-immunity
HPEHFLOH_02613 6.8e-99 S CAAX protease self-immunity
HPEHFLOH_02614 1.8e-30
HPEHFLOH_02615 0.0 helD 3.6.4.12 L DNA helicase
HPEHFLOH_02616 3.8e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HPEHFLOH_02617 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPEHFLOH_02618 9e-130 K UbiC transcription regulator-associated domain protein
HPEHFLOH_02619 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEHFLOH_02620 3.9e-24
HPEHFLOH_02621 2.6e-76 S Domain of unknown function (DUF3284)
HPEHFLOH_02622 1.5e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEHFLOH_02623 9.5e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HPEHFLOH_02624 2e-163 GK ROK family
HPEHFLOH_02625 1.6e-132 K Helix-turn-helix domain, rpiR family
HPEHFLOH_02626 4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPEHFLOH_02627 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HPEHFLOH_02628 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HPEHFLOH_02629 1.6e-177
HPEHFLOH_02630 3.9e-133 cobB K SIR2 family
HPEHFLOH_02631 2e-160 yunF F Protein of unknown function DUF72
HPEHFLOH_02632 2.6e-70 mutT 3.6.1.55 F DNA mismatch repair protein MutT
HPEHFLOH_02633 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPEHFLOH_02635 2.5e-209 bcr1 EGP Major facilitator Superfamily
HPEHFLOH_02636 1.1e-105 mutR K sequence-specific DNA binding
HPEHFLOH_02638 1.5e-146 tatD L hydrolase, TatD family
HPEHFLOH_02639 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HPEHFLOH_02640 2.3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPEHFLOH_02641 3.2e-37 veg S Biofilm formation stimulator VEG
HPEHFLOH_02642 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HPEHFLOH_02643 1.3e-181 S Prolyl oligopeptidase family
HPEHFLOH_02644 9.8e-129 fhuC 3.6.3.35 P ABC transporter
HPEHFLOH_02645 9.2e-131 znuB U ABC 3 transport family
HPEHFLOH_02647 0.0 ybfG M peptidoglycan-binding domain-containing protein
HPEHFLOH_02648 5.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPEHFLOH_02649 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
HPEHFLOH_02650 2.3e-107 L Integrase
HPEHFLOH_02651 2.5e-29
HPEHFLOH_02652 2.9e-176 L Initiator Replication protein
HPEHFLOH_02653 2.8e-88
HPEHFLOH_02654 2.2e-84 dps P Belongs to the Dps family
HPEHFLOH_02655 1.8e-145 XK26_04895
HPEHFLOH_02656 2.7e-103 L Phage integrase family
HPEHFLOH_02657 3.2e-62
HPEHFLOH_02658 1.1e-154 L Initiator Replication protein
HPEHFLOH_02659 8.8e-52
HPEHFLOH_02660 4.6e-102 yhdJ 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HPEHFLOH_02661 1.6e-104
HPEHFLOH_02662 1e-50 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HPEHFLOH_02663 3.4e-40 S RelB antitoxin
HPEHFLOH_02664 4e-107 L Integrase
HPEHFLOH_02665 4e-84
HPEHFLOH_02666 8.4e-38
HPEHFLOH_02670 7.7e-40 yddH CBM50 M Lysozyme-like
HPEHFLOH_02671 4.8e-30 yddG S maturation of SSU-rRNA
HPEHFLOH_02674 5.8e-186 yddE S AAA-like domain
HPEHFLOH_02677 6.4e-14 yddB S Conjugative transposon protein TcpC
HPEHFLOH_02679 7.5e-08 S Bacteriocin class IIc cyclic gassericin A-like
HPEHFLOH_02681 2.9e-53 V ATPases associated with a variety of cellular activities
HPEHFLOH_02682 1.6e-21 S ABC-2 family transporter protein
HPEHFLOH_02685 1e-58 S helicase activity
HPEHFLOH_02687 8e-68 C lyase activity
HPEHFLOH_02688 2e-219 L Transposase
HPEHFLOH_02689 8.4e-60 K Transcriptional regulator
HPEHFLOH_02690 4e-102 cadD P Cadmium resistance transporter
HPEHFLOH_02691 5.9e-192 L Psort location Cytoplasmic, score
HPEHFLOH_02692 2.8e-34
HPEHFLOH_02693 2.9e-117 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HPEHFLOH_02694 4.7e-241 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HPEHFLOH_02695 0.0 L MobA MobL family protein
HPEHFLOH_02696 7.2e-27
HPEHFLOH_02697 8.9e-41
HPEHFLOH_02698 2.3e-27
HPEHFLOH_02699 7.4e-43 relB L Addiction module antitoxin, RelB DinJ family
HPEHFLOH_02700 1e-41
HPEHFLOH_02701 1.2e-194 O Heat shock 70 kDa protein
HPEHFLOH_02702 1.4e-99 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HPEHFLOH_02703 3.5e-13 L Transposase and inactivated derivatives
HPEHFLOH_02704 1.3e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HPEHFLOH_02705 4.2e-164 corA P CorA-like Mg2+ transporter protein
HPEHFLOH_02706 1.7e-36 K sequence-specific DNA binding
HPEHFLOH_02707 6.1e-45 S Phage derived protein Gp49-like (DUF891)
HPEHFLOH_02708 2e-106 L Integrase
HPEHFLOH_02709 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HPEHFLOH_02710 2.7e-58 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HPEHFLOH_02711 1.2e-222 G Polysaccharide deacetylase
HPEHFLOH_02712 1.4e-25
HPEHFLOH_02713 5.8e-161 L Initiator Replication protein
HPEHFLOH_02714 0.0 pacL 3.6.3.8 P P-type ATPase
HPEHFLOH_02715 1.3e-41
HPEHFLOH_02716 1.1e-44 repA S Replication initiator protein A
HPEHFLOH_02717 1.5e-185 U Relaxase/Mobilisation nuclease domain
HPEHFLOH_02718 2.3e-54 S Bacterial mobilisation protein (MobC)
HPEHFLOH_02719 1.5e-27
HPEHFLOH_02721 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HPEHFLOH_02722 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
HPEHFLOH_02723 2.3e-107 L Integrase
HPEHFLOH_02724 4.6e-28
HPEHFLOH_02725 2e-27 S Protein of unknown function (DUF1093)
HPEHFLOH_02726 3.3e-132 yliE T Putative diguanylate phosphodiesterase
HPEHFLOH_02727 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HPEHFLOH_02728 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HPEHFLOH_02729 9.2e-212 norA EGP Major facilitator Superfamily
HPEHFLOH_02730 3.6e-117 yfbR S HD containing hydrolase-like enzyme
HPEHFLOH_02731 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPEHFLOH_02732 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPEHFLOH_02733 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPEHFLOH_02734 2.4e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HPEHFLOH_02735 3.9e-262 argH 4.3.2.1 E argininosuccinate lyase
HPEHFLOH_02736 9.3e-87 S Short repeat of unknown function (DUF308)
HPEHFLOH_02737 9.4e-161 rapZ S Displays ATPase and GTPase activities
HPEHFLOH_02738 1.2e-188 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HPEHFLOH_02739 3.7e-168 whiA K May be required for sporulation
HPEHFLOH_02740 2.6e-305 oppA E ABC transporter, substratebinding protein
HPEHFLOH_02741 1.1e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPEHFLOH_02742 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPEHFLOH_02744 1.2e-244 rpoN K Sigma-54 factor, core binding domain
HPEHFLOH_02745 1.8e-187 cggR K Putative sugar-binding domain
HPEHFLOH_02746 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPEHFLOH_02747 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HPEHFLOH_02748 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPEHFLOH_02749 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPEHFLOH_02750 3.1e-132
HPEHFLOH_02751 6.6e-295 clcA P chloride
HPEHFLOH_02752 1.2e-30 secG U Preprotein translocase
HPEHFLOH_02753 3.2e-138 est 3.1.1.1 S Serine aminopeptidase, S33
HPEHFLOH_02754 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPEHFLOH_02755 6e-82 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPEHFLOH_02756 4.2e-16 3.4.21.72 M Bacterial Ig-like domain (group 3)
HPEHFLOH_02757 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
HPEHFLOH_02758 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
HPEHFLOH_02759 1.5e-256 glnP P ABC transporter
HPEHFLOH_02760 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPEHFLOH_02761 6.1e-105 yxjI
HPEHFLOH_02762 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HPEHFLOH_02763 6.3e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPEHFLOH_02764 4.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HPEHFLOH_02765 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HPEHFLOH_02766 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
HPEHFLOH_02767 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
HPEHFLOH_02768 1.6e-153 xth 3.1.11.2 L exodeoxyribonuclease III
HPEHFLOH_02769 7.3e-161 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HPEHFLOH_02770 1.4e-167 murB 1.3.1.98 M Cell wall formation
HPEHFLOH_02771 0.0 yjcE P Sodium proton antiporter
HPEHFLOH_02772 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
HPEHFLOH_02773 7.1e-121 S Protein of unknown function (DUF1361)
HPEHFLOH_02774 1.7e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPEHFLOH_02775 1.6e-129 ybbR S YbbR-like protein
HPEHFLOH_02776 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPEHFLOH_02777 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPEHFLOH_02778 4.5e-123 yliE T EAL domain
HPEHFLOH_02779 9.3e-147 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HPEHFLOH_02780 7e-104 K Bacterial regulatory proteins, tetR family
HPEHFLOH_02781 4.4e-185 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HPEHFLOH_02782 4.3e-26 repB L Initiator Replication protein
HPEHFLOH_02784 2.3e-33 S Bacterial mobilisation protein (MobC)
HPEHFLOH_02785 3.6e-152 U Relaxase/Mobilisation nuclease domain
HPEHFLOH_02786 1.5e-42 S COG NOG38524 non supervised orthologous group
HPEHFLOH_02788 7.5e-29 yvbK 3.1.3.25 K GNAT family
HPEHFLOH_02789 5.6e-20 EGP Major facilitator Superfamily
HPEHFLOH_02790 7.7e-21
HPEHFLOH_02791 1.2e-198 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPEHFLOH_02792 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HPEHFLOH_02793 1e-154 L Integrase core domain
HPEHFLOH_02794 1.5e-52
HPEHFLOH_02795 3e-72
HPEHFLOH_02796 3e-131 1.5.1.39 C nitroreductase
HPEHFLOH_02797 6.9e-151 G Transmembrane secretion effector
HPEHFLOH_02798 7.5e-299 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HPEHFLOH_02799 7.8e-143
HPEHFLOH_02801 1.9e-71 spxA 1.20.4.1 P ArsC family
HPEHFLOH_02802 1.5e-33
HPEHFLOH_02803 2.5e-89 V VanZ like family
HPEHFLOH_02804 1.1e-240 EGP Major facilitator Superfamily
HPEHFLOH_02805 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HPEHFLOH_02806 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPEHFLOH_02807 7e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HPEHFLOH_02808 1.5e-152 licD M LicD family
HPEHFLOH_02809 1.3e-82 K Transcriptional regulator
HPEHFLOH_02810 1.5e-19
HPEHFLOH_02811 1.2e-225 pbuG S permease
HPEHFLOH_02812 1.7e-179 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPEHFLOH_02813 8.8e-150 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPEHFLOH_02814 2.6e-152 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HPEHFLOH_02815 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HPEHFLOH_02816 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HPEHFLOH_02817 7.7e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HPEHFLOH_02818 0.0 oatA I Acyltransferase
HPEHFLOH_02819 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HPEHFLOH_02820 5e-69 O OsmC-like protein
HPEHFLOH_02821 2.2e-45
HPEHFLOH_02822 1.1e-251 yfnA E Amino Acid
HPEHFLOH_02823 1.6e-87
HPEHFLOH_02824 1.6e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HPEHFLOH_02825 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HPEHFLOH_02826 1.8e-19
HPEHFLOH_02827 1.2e-103 gmk2 2.7.4.8 F Guanylate kinase
HPEHFLOH_02828 1.3e-81 zur P Belongs to the Fur family
HPEHFLOH_02829 7.1e-12 3.2.1.14 GH18
HPEHFLOH_02830 4.9e-148
HPEHFLOH_02831 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HPEHFLOH_02832 7.8e-211 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HPEHFLOH_02833 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPEHFLOH_02834 2.3e-40
HPEHFLOH_02836 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HPEHFLOH_02837 7.8e-149 glnH ET ABC transporter substrate-binding protein
HPEHFLOH_02838 1.6e-109 gluC P ABC transporter permease
HPEHFLOH_02839 4e-108 glnP P ABC transporter permease
HPEHFLOH_02840 1e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HPEHFLOH_02841 1.4e-153 K CAT RNA binding domain
HPEHFLOH_02842 4.4e-256 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HPEHFLOH_02843 8.4e-142 G YdjC-like protein
HPEHFLOH_02844 1.2e-73 steT E amino acid
HPEHFLOH_02845 1.6e-67 steT E amino acid
HPEHFLOH_02846 1.1e-58 steT E amino acid
HPEHFLOH_02847 1.6e-73 mgrA K helix_turn_helix multiple antibiotic resistance protein
HPEHFLOH_02848 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
HPEHFLOH_02849 5.7e-71 K MarR family
HPEHFLOH_02850 4.9e-210 EGP Major facilitator Superfamily
HPEHFLOH_02851 3.8e-85 S membrane transporter protein
HPEHFLOH_02852 7.1e-98 K Bacterial regulatory proteins, tetR family
HPEHFLOH_02853 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPEHFLOH_02854 2.9e-78 3.6.1.55 F NUDIX domain
HPEHFLOH_02855 5.5e-47 sugE U Multidrug resistance protein
HPEHFLOH_02856 1.2e-26
HPEHFLOH_02857 5.5e-129 pgm3 G Phosphoglycerate mutase family
HPEHFLOH_02858 4.7e-125 pgm3 G Phosphoglycerate mutase family
HPEHFLOH_02859 0.0 yjbQ P TrkA C-terminal domain protein
HPEHFLOH_02860 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
HPEHFLOH_02861 2.5e-110 dedA S SNARE associated Golgi protein
HPEHFLOH_02862 0.0 helD 3.6.4.12 L DNA helicase
HPEHFLOH_02863 1.1e-164 fabK 1.3.1.9 S Nitronate monooxygenase
HPEHFLOH_02864 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HPEHFLOH_02865 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HPEHFLOH_02867 6e-284 yeeA V Type II restriction enzyme, methylase subunits
HPEHFLOH_02868 1.1e-41 yeeA V Type II restriction enzyme, methylase subunits
HPEHFLOH_02869 3.3e-291 yeeB L DEAD-like helicases superfamily
HPEHFLOH_02870 3.6e-131 pstS P T5orf172
HPEHFLOH_02872 5.2e-28 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPEHFLOH_02873 4e-79 L AAA domain
HPEHFLOH_02874 4.3e-101 K Transcriptional regulator, AbiEi antitoxin
HPEHFLOH_02875 3.2e-137 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HPEHFLOH_02876 1.4e-27 K Helix-turn-helix XRE-family like proteins
HPEHFLOH_02877 5.3e-49
HPEHFLOH_02878 5.1e-60 K Helix-turn-helix XRE-family like proteins
HPEHFLOH_02879 2.2e-109 XK27_07075 V CAAX protease self-immunity
HPEHFLOH_02880 2.7e-160 S Cysteine-rich secretory protein family
HPEHFLOH_02881 2.9e-48 K Cro/C1-type HTH DNA-binding domain
HPEHFLOH_02882 2.6e-68 D nuclear chromosome segregation
HPEHFLOH_02883 3.4e-66
HPEHFLOH_02884 8.7e-153 S Domain of unknown function (DUF4767)
HPEHFLOH_02885 1.9e-48
HPEHFLOH_02886 5.7e-38 S MORN repeat
HPEHFLOH_02887 0.0 XK27_09800 I Acyltransferase family
HPEHFLOH_02888 7.1e-37 S Transglycosylase associated protein
HPEHFLOH_02889 5.7e-84
HPEHFLOH_02890 7.2e-23
HPEHFLOH_02891 8.7e-72 asp S Asp23 family, cell envelope-related function
HPEHFLOH_02892 5.3e-72 asp2 S Asp23 family, cell envelope-related function
HPEHFLOH_02893 3.5e-146 Q Fumarylacetoacetate (FAA) hydrolase family
HPEHFLOH_02894 4.2e-157 yjdB S Domain of unknown function (DUF4767)
HPEHFLOH_02895 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HPEHFLOH_02896 7.3e-148 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPEHFLOH_02897 2.2e-65 S Putative inner membrane protein (DUF1819)
HPEHFLOH_02898 4.1e-72 S Domain of unknown function (DUF1788)
HPEHFLOH_02899 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HPEHFLOH_02900 0.0 2.1.1.72 LV Eco57I restriction-modification methylase
HPEHFLOH_02901 2.3e-148 L Belongs to the 'phage' integrase family
HPEHFLOH_02902 1.3e-168 V Type II restriction enzyme, methylase subunits
HPEHFLOH_02903 1.9e-230 S PglZ domain
HPEHFLOH_02904 0.0 pepN 3.4.11.2 E aminopeptidase
HPEHFLOH_02906 3.7e-49 N Uncharacterized conserved protein (DUF2075)
HPEHFLOH_02907 1.6e-25 L Helix-turn-helix domain
HPEHFLOH_02908 1.7e-88 L PFAM Integrase catalytic region
HPEHFLOH_02909 2.4e-17
HPEHFLOH_02910 4.7e-91 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
HPEHFLOH_02911 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HPEHFLOH_02913 3.5e-88 S AAA domain
HPEHFLOH_02914 1.9e-130 K sequence-specific DNA binding
HPEHFLOH_02915 9.5e-95 K Helix-turn-helix domain
HPEHFLOH_02916 2.3e-170 K Transcriptional regulator
HPEHFLOH_02917 0.0 1.3.5.4 C FMN_bind
HPEHFLOH_02919 4.3e-80 rmaD K Transcriptional regulator
HPEHFLOH_02920 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HPEHFLOH_02921 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HPEHFLOH_02922 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
HPEHFLOH_02923 3.3e-277 pipD E Dipeptidase
HPEHFLOH_02924 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HPEHFLOH_02925 8.5e-41
HPEHFLOH_02926 4.1e-32 L leucine-zipper of insertion element IS481
HPEHFLOH_02927 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HPEHFLOH_02928 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HPEHFLOH_02929 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HPEHFLOH_02930 5.6e-138 S NADPH-dependent FMN reductase
HPEHFLOH_02931 2.5e-178
HPEHFLOH_02932 1.4e-218 yibE S overlaps another CDS with the same product name
HPEHFLOH_02933 1.3e-126 yibF S overlaps another CDS with the same product name
HPEHFLOH_02934 5.7e-103 3.2.2.20 K FR47-like protein
HPEHFLOH_02935 4.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HPEHFLOH_02936 5.6e-49
HPEHFLOH_02937 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
HPEHFLOH_02938 1e-254 xylP2 G symporter
HPEHFLOH_02939 5.8e-280 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPEHFLOH_02940 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HPEHFLOH_02941 0.0 asnB 6.3.5.4 E Asparagine synthase
HPEHFLOH_02942 9.4e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HPEHFLOH_02943 1.7e-120 azlC E branched-chain amino acid
HPEHFLOH_02944 4.4e-35 yyaN K MerR HTH family regulatory protein
HPEHFLOH_02945 9.3e-106
HPEHFLOH_02946 1.4e-117 S Domain of unknown function (DUF4811)
HPEHFLOH_02947 7e-270 lmrB EGP Major facilitator Superfamily
HPEHFLOH_02948 1.7e-84 merR K MerR HTH family regulatory protein
HPEHFLOH_02949 1.3e-57
HPEHFLOH_02950 2e-120 sirR K iron dependent repressor
HPEHFLOH_02951 6e-31 cspC K Cold shock protein
HPEHFLOH_02952 3.3e-130 thrE S Putative threonine/serine exporter
HPEHFLOH_02953 2.2e-76 S Threonine/Serine exporter, ThrE
HPEHFLOH_02954 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HPEHFLOH_02955 3.9e-119 lssY 3.6.1.27 I phosphatase
HPEHFLOH_02956 2e-154 I alpha/beta hydrolase fold
HPEHFLOH_02957 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
HPEHFLOH_02958 4.2e-92 K Transcriptional regulator
HPEHFLOH_02959 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HPEHFLOH_02960 1.5e-264 lysP E amino acid
HPEHFLOH_02961 5.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HPEHFLOH_02962 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HPEHFLOH_02963 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPEHFLOH_02971 6.9e-78 ctsR K Belongs to the CtsR family
HPEHFLOH_02972 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPEHFLOH_02973 1.5e-109 K Bacterial regulatory proteins, tetR family
HPEHFLOH_02974 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPEHFLOH_02975 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPEHFLOH_02976 7.8e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HPEHFLOH_02977 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPEHFLOH_02978 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPEHFLOH_02979 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPEHFLOH_02980 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HPEHFLOH_02981 7.5e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPEHFLOH_02982 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HPEHFLOH_02983 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPEHFLOH_02984 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPEHFLOH_02985 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPEHFLOH_02986 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPEHFLOH_02987 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPEHFLOH_02988 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPEHFLOH_02989 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HPEHFLOH_02990 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPEHFLOH_02991 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPEHFLOH_02992 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPEHFLOH_02993 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPEHFLOH_02994 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPEHFLOH_02995 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPEHFLOH_02996 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPEHFLOH_02997 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPEHFLOH_02998 2.2e-24 rpmD J Ribosomal protein L30
HPEHFLOH_02999 6.3e-70 rplO J Binds to the 23S rRNA
HPEHFLOH_03000 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPEHFLOH_03001 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPEHFLOH_03002 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPEHFLOH_03003 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPEHFLOH_03004 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPEHFLOH_03005 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPEHFLOH_03006 2.1e-61 rplQ J Ribosomal protein L17
HPEHFLOH_03007 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPEHFLOH_03008 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HPEHFLOH_03009 1.4e-86 ynhH S NusG domain II
HPEHFLOH_03010 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HPEHFLOH_03011 3.5e-142 cad S FMN_bind
HPEHFLOH_03012 1.2e-224 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPEHFLOH_03013 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPEHFLOH_03014 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPEHFLOH_03015 5e-145 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HPEHFLOH_03016 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPEHFLOH_03017 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPEHFLOH_03018 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HPEHFLOH_03019 3.4e-163 degV S Uncharacterised protein, DegV family COG1307
HPEHFLOH_03020 2.7e-183 ywhK S Membrane
HPEHFLOH_03021 7.6e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HPEHFLOH_03022 6.2e-45 isplu5A L PFAM transposase IS200-family protein
HPEHFLOH_03023 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HPEHFLOH_03024 9.1e-164 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HPEHFLOH_03025 3.4e-183 aroF 2.5.1.54 E DAHP synthetase I family
HPEHFLOH_03026 5.2e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HPEHFLOH_03027 1.6e-263 P Sodium:sulfate symporter transmembrane region
HPEHFLOH_03028 2.6e-52 yitW S Iron-sulfur cluster assembly protein
HPEHFLOH_03029 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
HPEHFLOH_03030 1.3e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
HPEHFLOH_03031 3.5e-199 K Helix-turn-helix domain
HPEHFLOH_03032 1.4e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HPEHFLOH_03033 1.3e-131 mntB 3.6.3.35 P ABC transporter
HPEHFLOH_03034 4.8e-141 mtsB U ABC 3 transport family
HPEHFLOH_03035 4.6e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
HPEHFLOH_03036 3.1e-50
HPEHFLOH_03037 1.6e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HPEHFLOH_03038 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
HPEHFLOH_03039 2.9e-179 citR K sugar-binding domain protein
HPEHFLOH_03040 1.7e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HPEHFLOH_03041 5.7e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HPEHFLOH_03042 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
HPEHFLOH_03043 6.7e-162 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HPEHFLOH_03044 2.3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HPEHFLOH_03045 9.2e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HPEHFLOH_03046 2.8e-252 frdC 1.3.5.4 C FAD binding domain
HPEHFLOH_03047 1.4e-93 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HPEHFLOH_03048 4.9e-162 mleR K LysR family transcriptional regulator
HPEHFLOH_03049 1.8e-167 mleR K LysR family
HPEHFLOH_03050 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HPEHFLOH_03051 1.4e-165 mleP S Sodium Bile acid symporter family
HPEHFLOH_03052 5.8e-253 yfnA E Amino Acid
HPEHFLOH_03053 2e-98 S ECF transporter, substrate-specific component
HPEHFLOH_03054 1.8e-23
HPEHFLOH_03055 1.6e-283 S Alpha beta
HPEHFLOH_03056 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
HPEHFLOH_03057 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HPEHFLOH_03058 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HPEHFLOH_03059 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HPEHFLOH_03060 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
HPEHFLOH_03061 2.8e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HPEHFLOH_03062 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HPEHFLOH_03063 3.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
HPEHFLOH_03064 9e-113 acmA 3.2.1.17 NU mannosyl-glycoprotein
HPEHFLOH_03065 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPEHFLOH_03066 4.9e-85 S UPF0316 protein
HPEHFLOH_03067 1.1e-217 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HPEHFLOH_03068 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HPEHFLOH_03069 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPEHFLOH_03070 2.6e-198 camS S sex pheromone
HPEHFLOH_03071 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPEHFLOH_03072 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPEHFLOH_03073 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPEHFLOH_03074 1e-190 yegS 2.7.1.107 G Lipid kinase
HPEHFLOH_03075 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPEHFLOH_03076 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
HPEHFLOH_03077 0.0 yfgQ P E1-E2 ATPase
HPEHFLOH_03078 1.4e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HPEHFLOH_03079 4.3e-166 S Alpha/beta hydrolase of unknown function (DUF915)
HPEHFLOH_03080 2.3e-151 gntR K rpiR family
HPEHFLOH_03081 4.1e-144 lys M Glycosyl hydrolases family 25
HPEHFLOH_03082 2.6e-155 L Transposase
HPEHFLOH_03083 1.4e-72 cps2J S Polysaccharide biosynthesis protein
HPEHFLOH_03084 1.6e-68 wcmJ S SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
HPEHFLOH_03085 1.4e-35 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HPEHFLOH_03086 1.3e-117
HPEHFLOH_03087 2.1e-66 L Putative transposase of IS4/5 family (DUF4096)
HPEHFLOH_03088 1.1e-65 L Transposase DDE domain
HPEHFLOH_03089 3.3e-200 cps3I G Acyltransferase family
HPEHFLOH_03090 2e-146 cps1D M Domain of unknown function (DUF4422)
HPEHFLOH_03091 1.3e-241 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HPEHFLOH_03092 3.5e-94 rfbP M Bacterial sugar transferase
HPEHFLOH_03093 3.8e-53
HPEHFLOH_03094 7.3e-33 S Protein of unknown function (DUF2922)
HPEHFLOH_03095 7e-30
HPEHFLOH_03096 1e-27
HPEHFLOH_03097 6.8e-101 K DNA-templated transcription, initiation
HPEHFLOH_03098 4.3e-124
HPEHFLOH_03099 1.1e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
HPEHFLOH_03100 4.1e-106 ygaC J Belongs to the UPF0374 family
HPEHFLOH_03101 1.3e-134 cwlO M NlpC/P60 family
HPEHFLOH_03102 7.8e-48 K sequence-specific DNA binding
HPEHFLOH_03103 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
HPEHFLOH_03104 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HPEHFLOH_03105 9.3e-188 yueF S AI-2E family transporter
HPEHFLOH_03106 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HPEHFLOH_03107 9.5e-213 gntP EG Gluconate
HPEHFLOH_03108 9.7e-291 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HPEHFLOH_03109 8.6e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HPEHFLOH_03110 1.4e-253 gor 1.8.1.7 C Glutathione reductase
HPEHFLOH_03111 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPEHFLOH_03112 7.8e-274
HPEHFLOH_03113 6.5e-198 M MucBP domain
HPEHFLOH_03114 4.6e-160 lysR5 K LysR substrate binding domain
HPEHFLOH_03115 5.5e-126 yxaA S membrane transporter protein
HPEHFLOH_03116 3.2e-57 ywjH S Protein of unknown function (DUF1634)
HPEHFLOH_03117 1.3e-309 oppA E ABC transporter, substratebinding protein
HPEHFLOH_03118 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPEHFLOH_03119 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HPEHFLOH_03120 9.2e-203 oppD P Belongs to the ABC transporter superfamily
HPEHFLOH_03121 4e-181 oppF P Belongs to the ABC transporter superfamily
HPEHFLOH_03122 1e-63 K Winged helix DNA-binding domain
HPEHFLOH_03123 8.2e-102 L Integrase
HPEHFLOH_03124 0.0 clpE O Belongs to the ClpA ClpB family
HPEHFLOH_03125 6.5e-30
HPEHFLOH_03126 2.7e-39 ptsH G phosphocarrier protein HPR
HPEHFLOH_03127 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPEHFLOH_03128 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HPEHFLOH_03129 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
HPEHFLOH_03130 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HPEHFLOH_03131 9.5e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HPEHFLOH_03132 5.4e-228 patA 2.6.1.1 E Aminotransferase
HPEHFLOH_03133 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
HPEHFLOH_03134 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)