ORF_ID e_value Gene_name EC_number CAZy COGs Description
LOOOCGKK_00011 5.3e-11
LOOOCGKK_00017 2.1e-138 mreC M Involved in formation and maintenance of cell shape
LOOOCGKK_00018 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LOOOCGKK_00019 1.4e-89 usp 3.5.1.28 CBM50 S CHAP domain
LOOOCGKK_00020 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LOOOCGKK_00021 2.9e-218 araT 2.6.1.1 E Aminotransferase
LOOOCGKK_00022 7e-144 recO L Involved in DNA repair and RecF pathway recombination
LOOOCGKK_00023 2.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LOOOCGKK_00024 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOOOCGKK_00025 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LOOOCGKK_00026 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOOOCGKK_00027 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LOOOCGKK_00028 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LOOOCGKK_00029 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LOOOCGKK_00030 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LOOOCGKK_00031 2e-25 WQ51_00785
LOOOCGKK_00032 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LOOOCGKK_00033 2.2e-218 ywbD 2.1.1.191 J Methyltransferase
LOOOCGKK_00034 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LOOOCGKK_00035 2.4e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LOOOCGKK_00036 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LOOOCGKK_00037 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LOOOCGKK_00038 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LOOOCGKK_00039 3.2e-53 yheA S Belongs to the UPF0342 family
LOOOCGKK_00040 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LOOOCGKK_00041 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LOOOCGKK_00042 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LOOOCGKK_00043 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
LOOOCGKK_00044 2.4e-251 msrR K Transcriptional regulator
LOOOCGKK_00045 2.8e-83 ydiA P C4-dicarboxylate transporter malic acid transport protein
LOOOCGKK_00046 5e-51 ydiA P C4-dicarboxylate transporter malic acid transport protein
LOOOCGKK_00047 3.5e-202 I acyl-CoA dehydrogenase
LOOOCGKK_00048 4.5e-97 mip S hydroperoxide reductase activity
LOOOCGKK_00049 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOOOCGKK_00050 4.7e-106
LOOOCGKK_00051 1.3e-31 K Cro/C1-type HTH DNA-binding domain
LOOOCGKK_00052 3e-49 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
LOOOCGKK_00053 1.5e-25 estA E GDSL-like Lipase/Acylhydrolase
LOOOCGKK_00054 1.3e-95
LOOOCGKK_00055 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LOOOCGKK_00056 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LOOOCGKK_00057 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LOOOCGKK_00058 1.6e-183 S CRISPR-associated protein Csn2 subfamily St
LOOOCGKK_00059 7.8e-146 ycgQ S TIGR03943 family
LOOOCGKK_00060 7.1e-156 XK27_03015 S permease
LOOOCGKK_00062 0.0 yhgF K Transcriptional accessory protein
LOOOCGKK_00063 9.9e-42 pspC KT PspC domain
LOOOCGKK_00064 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LOOOCGKK_00065 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LOOOCGKK_00067 5.5e-69 ytxH S General stress protein
LOOOCGKK_00069 2e-177 yegQ O Peptidase U32
LOOOCGKK_00070 3.4e-252 yegQ O Peptidase U32
LOOOCGKK_00071 8.1e-46 S CHY zinc finger
LOOOCGKK_00072 8.4e-88 bioY S biotin synthase
LOOOCGKK_00074 1.1e-33 XK27_12190 S protein conserved in bacteria
LOOOCGKK_00075 5.1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
LOOOCGKK_00076 4.3e-12
LOOOCGKK_00077 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
LOOOCGKK_00078 4.1e-225 mutH L DNA mismatch repair enzyme MutH
LOOOCGKK_00079 4e-29 S SIR2-like domain
LOOOCGKK_00080 2.1e-167 S SIR2-like domain
LOOOCGKK_00081 3.2e-167 S Domain of unknown function DUF87
LOOOCGKK_00083 8.2e-35
LOOOCGKK_00084 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LOOOCGKK_00085 1.9e-15 M LysM domain
LOOOCGKK_00086 2.4e-58 M LysM domain
LOOOCGKK_00087 3.1e-20
LOOOCGKK_00088 5.4e-172 S hydrolase
LOOOCGKK_00089 7.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
LOOOCGKK_00090 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LOOOCGKK_00091 5.9e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
LOOOCGKK_00092 2.1e-27 P Hemerythrin HHE cation binding domain protein
LOOOCGKK_00093 1.4e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOOOCGKK_00094 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
LOOOCGKK_00095 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
LOOOCGKK_00096 8.3e-76 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LOOOCGKK_00097 1.4e-44 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LOOOCGKK_00098 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
LOOOCGKK_00099 5.6e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
LOOOCGKK_00100 1e-146 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
LOOOCGKK_00101 9.5e-149 L Protein of unknown function (DUF2813)
LOOOCGKK_00102 2.6e-92 pcrA1 3.6.4.12 L UvrD/REP helicase N-terminal domain
LOOOCGKK_00103 1.4e-10 endA F DNA/RNA non-specific endonuclease
LOOOCGKK_00104 1.2e-33
LOOOCGKK_00105 1.7e-188 higA K Pfam:DUF955
LOOOCGKK_00106 1.7e-174 spd F DNA RNA non-specific endonuclease
LOOOCGKK_00107 1.5e-92 lemA S LemA family
LOOOCGKK_00108 1.8e-135 htpX O Belongs to the peptidase M48B family
LOOOCGKK_00109 4.2e-75 S Psort location CytoplasmicMembrane, score
LOOOCGKK_00110 6.2e-56 S Domain of unknown function (DUF4430)
LOOOCGKK_00111 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LOOOCGKK_00112 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
LOOOCGKK_00113 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
LOOOCGKK_00114 2.7e-160 L Transposase
LOOOCGKK_00115 3e-50 L Transposase
LOOOCGKK_00116 2.6e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
LOOOCGKK_00117 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
LOOOCGKK_00118 3.5e-91 dps P Belongs to the Dps family
LOOOCGKK_00119 1.1e-80 perR P Belongs to the Fur family
LOOOCGKK_00120 8.4e-28 yqgQ S protein conserved in bacteria
LOOOCGKK_00121 2.2e-179 glk 2.7.1.2 G Glucokinase
LOOOCGKK_00122 0.0 typA T GTP-binding protein TypA
LOOOCGKK_00124 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LOOOCGKK_00125 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LOOOCGKK_00126 8.2e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LOOOCGKK_00127 2.9e-249 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LOOOCGKK_00128 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LOOOCGKK_00129 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LOOOCGKK_00130 1.4e-96 sepF D cell septum assembly
LOOOCGKK_00131 2e-34 yggT D integral membrane protein
LOOOCGKK_00132 1.8e-142 ylmH T S4 RNA-binding domain
LOOOCGKK_00133 1.8e-135 divIVA D Cell division protein DivIVA
LOOOCGKK_00134 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LOOOCGKK_00135 5.5e-30
LOOOCGKK_00136 8.4e-10
LOOOCGKK_00137 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
LOOOCGKK_00138 2e-45 rpmE2 J 50S ribosomal protein L31
LOOOCGKK_00139 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LOOOCGKK_00140 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
LOOOCGKK_00141 8.9e-155 gst O Glutathione S-transferase
LOOOCGKK_00142 1.3e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LOOOCGKK_00143 4.5e-111 tdk 2.7.1.21 F thymidine kinase
LOOOCGKK_00144 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LOOOCGKK_00145 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LOOOCGKK_00146 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LOOOCGKK_00147 1.5e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LOOOCGKK_00148 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
LOOOCGKK_00149 8e-100 pvaA M lytic transglycosylase activity
LOOOCGKK_00150 0.0 yfiB1 V abc transporter atp-binding protein
LOOOCGKK_00151 0.0 XK27_10035 V abc transporter atp-binding protein
LOOOCGKK_00152 2.3e-295 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOOOCGKK_00153 4.6e-238 dltB M Membrane protein involved in D-alanine export
LOOOCGKK_00154 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOOOCGKK_00155 4.4e-228 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LOOOCGKK_00156 0.0 3.6.3.8 P cation transport ATPase
LOOOCGKK_00157 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
LOOOCGKK_00159 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LOOOCGKK_00160 3.6e-165 metF 1.5.1.20 C reductase
LOOOCGKK_00161 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LOOOCGKK_00162 1.7e-94 panT S ECF transporter, substrate-specific component
LOOOCGKK_00163 4.8e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LOOOCGKK_00164 2.8e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
LOOOCGKK_00165 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LOOOCGKK_00166 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOOOCGKK_00167 2.8e-40 T PhoQ Sensor
LOOOCGKK_00168 1.7e-43 T PhoQ Sensor
LOOOCGKK_00169 4.2e-127 T PhoQ Sensor
LOOOCGKK_00170 2.1e-30 rpsT J rRNA binding
LOOOCGKK_00171 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
LOOOCGKK_00172 3.2e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
LOOOCGKK_00173 2.3e-26 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
LOOOCGKK_00174 1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
LOOOCGKK_00175 1.3e-21 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
LOOOCGKK_00176 8.2e-65 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
LOOOCGKK_00177 5.5e-29 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LOOOCGKK_00178 1.5e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LOOOCGKK_00179 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LOOOCGKK_00180 2.6e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
LOOOCGKK_00181 3.5e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LOOOCGKK_00182 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
LOOOCGKK_00183 6.3e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
LOOOCGKK_00184 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LOOOCGKK_00185 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LOOOCGKK_00186 6.8e-81 ypmB S Protein conserved in bacteria
LOOOCGKK_00187 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LOOOCGKK_00188 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LOOOCGKK_00189 1.5e-07
LOOOCGKK_00190 8.7e-38 L Transposase
LOOOCGKK_00191 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
LOOOCGKK_00192 7.5e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LOOOCGKK_00193 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
LOOOCGKK_00194 7.2e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LOOOCGKK_00195 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
LOOOCGKK_00196 7.3e-20 D nuclear chromosome segregation
LOOOCGKK_00197 5.3e-136 yejC S cyclic nucleotide-binding protein
LOOOCGKK_00198 1.2e-163 rapZ S Displays ATPase and GTPase activities
LOOOCGKK_00199 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LOOOCGKK_00200 8.7e-162 whiA K May be required for sporulation
LOOOCGKK_00201 1.1e-55 pepD E Dipeptidase
LOOOCGKK_00202 1.9e-61 pepD E Dipeptidase
LOOOCGKK_00203 5.4e-32 cspD K Cold shock protein domain
LOOOCGKK_00204 9.4e-43 K Cold-Shock Protein
LOOOCGKK_00205 0.0 copB 3.6.3.4 P P-type ATPase
LOOOCGKK_00206 1.6e-104 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
LOOOCGKK_00207 4e-09
LOOOCGKK_00208 8.2e-13 K Transcriptional
LOOOCGKK_00210 4.5e-87 L Replication initiation factor
LOOOCGKK_00211 4.5e-10 S Domain of unknown function (DUF3173)
LOOOCGKK_00212 7.7e-216 L Belongs to the 'phage' integrase family
LOOOCGKK_00213 9.6e-77 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
LOOOCGKK_00214 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LOOOCGKK_00215 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LOOOCGKK_00216 1.3e-97 cysE 2.3.1.30 E serine acetyltransferase
LOOOCGKK_00217 2.7e-57 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
LOOOCGKK_00218 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
LOOOCGKK_00219 7.5e-150 glcU U Glucose uptake
LOOOCGKK_00220 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
LOOOCGKK_00221 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
LOOOCGKK_00222 2.5e-111 XK27_10720 D peptidase activity
LOOOCGKK_00223 1.8e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
LOOOCGKK_00224 1.7e-08
LOOOCGKK_00225 2.3e-171 yeiH S Membrane
LOOOCGKK_00226 1.9e-119 mur1 NU muramidase
LOOOCGKK_00227 1.2e-97 L transposition
LOOOCGKK_00228 2.6e-166 cpsY K Transcriptional regulator
LOOOCGKK_00229 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LOOOCGKK_00230 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
LOOOCGKK_00231 2e-104 artQ P ABC transporter (Permease
LOOOCGKK_00232 6.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
LOOOCGKK_00233 7.1e-158 aatB ET ABC transporter substrate-binding protein
LOOOCGKK_00234 3.7e-140 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOOOCGKK_00235 2.1e-07
LOOOCGKK_00236 3.4e-58 adhP 1.1.1.1 C alcohol dehydrogenase
LOOOCGKK_00237 7.1e-113 adhP 1.1.1.1 C alcohol dehydrogenase
LOOOCGKK_00239 1.1e-20
LOOOCGKK_00240 0.0 res_1 3.1.21.5 S Type III restriction
LOOOCGKK_00241 2.5e-294 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
LOOOCGKK_00242 6.5e-63 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
LOOOCGKK_00243 5.1e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LOOOCGKK_00244 4.5e-126 gntR1 K transcriptional
LOOOCGKK_00245 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LOOOCGKK_00246 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LOOOCGKK_00247 4.1e-87 niaX
LOOOCGKK_00248 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
LOOOCGKK_00249 6.9e-127 K DNA-binding helix-turn-helix protein
LOOOCGKK_00250 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LOOOCGKK_00251 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LOOOCGKK_00252 4.1e-167 GK ROK family
LOOOCGKK_00253 8.3e-159 dprA LU DNA protecting protein DprA
LOOOCGKK_00254 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LOOOCGKK_00255 1.4e-150 S TraX protein
LOOOCGKK_00256 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOOOCGKK_00257 2.4e-251 T PhoQ Sensor
LOOOCGKK_00258 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LOOOCGKK_00259 1.9e-152 XK27_05470 E Methionine synthase
LOOOCGKK_00260 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LOOOCGKK_00261 1.2e-36 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LOOOCGKK_00262 3.4e-50 IQ Acetoin reductase
LOOOCGKK_00263 3.9e-19 IQ Acetoin reductase
LOOOCGKK_00264 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LOOOCGKK_00268 4.1e-53 K peptidyl-tyrosine sulfation
LOOOCGKK_00269 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LOOOCGKK_00272 1.3e-212 pqqE C radical SAM domain protein
LOOOCGKK_00273 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
LOOOCGKK_00274 6.6e-61 EGP Major facilitator Superfamily
LOOOCGKK_00275 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LOOOCGKK_00276 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
LOOOCGKK_00277 6.4e-104 V ABC transporter (Permease
LOOOCGKK_00278 4.1e-114 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOOOCGKK_00279 1.6e-10
LOOOCGKK_00280 1.2e-103 K Transcriptional regulator, TetR family
LOOOCGKK_00281 1.5e-158 czcD P cation diffusion facilitator family transporter
LOOOCGKK_00282 1e-209 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LOOOCGKK_00283 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
LOOOCGKK_00284 6e-08 S Hydrolases of the alpha beta superfamily
LOOOCGKK_00285 1.8e-16 S Alpha/beta hydrolase of unknown function (DUF915)
LOOOCGKK_00286 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
LOOOCGKK_00289 2.6e-143 2.4.2.3 F Phosphorylase superfamily
LOOOCGKK_00290 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
LOOOCGKK_00291 6.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
LOOOCGKK_00292 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
LOOOCGKK_00293 8.8e-55 dinF V Mate efflux family protein
LOOOCGKK_00295 2.1e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LOOOCGKK_00297 9.7e-89 S TraX protein
LOOOCGKK_00298 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
LOOOCGKK_00299 1.5e-149 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LOOOCGKK_00300 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LOOOCGKK_00301 7.2e-79 L transposase activity
LOOOCGKK_00302 1.3e-49 L transposition
LOOOCGKK_00303 6.3e-34 L Integrase core domain protein
LOOOCGKK_00304 2.3e-161 S CHAP domain
LOOOCGKK_00305 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
LOOOCGKK_00306 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LOOOCGKK_00307 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LOOOCGKK_00308 9.2e-141 1.1.1.169 H Ketopantoate reductase
LOOOCGKK_00309 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LOOOCGKK_00310 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LOOOCGKK_00311 7.1e-209 sip L Belongs to the 'phage' integrase family
LOOOCGKK_00312 3.9e-15 xre K Transcriptional
LOOOCGKK_00313 1.2e-17
LOOOCGKK_00317 7.9e-14
LOOOCGKK_00318 2e-21
LOOOCGKK_00319 3.8e-135 KL Phage plasmid primase P4 family
LOOOCGKK_00320 1.9e-67 S Virulence-associated protein E
LOOOCGKK_00321 1.8e-36 L Transposase
LOOOCGKK_00322 4.8e-54 L Transposase
LOOOCGKK_00323 1.5e-196 dcm 2.1.1.37 H cytosine-specific methyltransferase
LOOOCGKK_00324 5.3e-168 S NgoFVII restriction endonuclease
LOOOCGKK_00326 3.8e-25
LOOOCGKK_00327 1.4e-149 V Abi-like protein
LOOOCGKK_00329 8.2e-70 argR K Regulates arginine biosynthesis genes
LOOOCGKK_00330 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LOOOCGKK_00331 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LOOOCGKK_00332 7e-34 S Protein of unknown function (DUF3021)
LOOOCGKK_00333 1.2e-61 KT phosphorelay signal transduction system
LOOOCGKK_00335 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LOOOCGKK_00337 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LOOOCGKK_00338 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
LOOOCGKK_00339 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
LOOOCGKK_00340 2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LOOOCGKK_00341 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
LOOOCGKK_00342 2.8e-111 cas1 L maintenance of DNA repeat elements
LOOOCGKK_00343 2.2e-69 cas1 L maintenance of DNA repeat elements
LOOOCGKK_00344 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LOOOCGKK_00345 2e-132 cas6 S Pfam:DUF2276
LOOOCGKK_00346 7.3e-107 csm1 S CRISPR-associated protein Csm1 family
LOOOCGKK_00347 2.2e-37 csm2 L Csm2 Type III-A
LOOOCGKK_00348 9.9e-115 csm3 L RAMP superfamily
LOOOCGKK_00349 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
LOOOCGKK_00350 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
LOOOCGKK_00351 2.1e-14 csm6 S Psort location Cytoplasmic, score
LOOOCGKK_00352 9.8e-73 csm6 S Psort location Cytoplasmic, score
LOOOCGKK_00353 5.9e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LOOOCGKK_00354 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LOOOCGKK_00356 8.1e-48 nylA 3.5.1.4 J Belongs to the amidase family
LOOOCGKK_00357 6.1e-266 dtpT E transporter
LOOOCGKK_00358 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
LOOOCGKK_00359 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
LOOOCGKK_00360 1.8e-67 yecS P ABC transporter (Permease
LOOOCGKK_00362 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
LOOOCGKK_00363 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
LOOOCGKK_00364 1.4e-104 yfiF3 K sequence-specific DNA binding
LOOOCGKK_00365 4.6e-238 L Transposase
LOOOCGKK_00366 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LOOOCGKK_00367 1.8e-240 agcS E (Alanine) symporter
LOOOCGKK_00368 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LOOOCGKK_00369 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
LOOOCGKK_00370 1.3e-54 Q phosphatase activity
LOOOCGKK_00371 9.3e-62 S haloacid dehalogenase-like hydrolase
LOOOCGKK_00372 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LOOOCGKK_00373 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
LOOOCGKK_00374 1e-145 XK27_04775 S hemerythrin HHE cation binding domain
LOOOCGKK_00375 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
LOOOCGKK_00376 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LOOOCGKK_00377 2.6e-174 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LOOOCGKK_00378 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LOOOCGKK_00379 1.9e-43 yktA S Belongs to the UPF0223 family
LOOOCGKK_00380 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
LOOOCGKK_00381 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
LOOOCGKK_00382 1.3e-157 pstS P phosphate
LOOOCGKK_00383 3.2e-156 pstC P probably responsible for the translocation of the substrate across the membrane
LOOOCGKK_00384 1.2e-155 pstA P phosphate transport system permease
LOOOCGKK_00385 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LOOOCGKK_00386 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LOOOCGKK_00387 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
LOOOCGKK_00388 0.0 pepN 3.4.11.2 E aminopeptidase
LOOOCGKK_00389 1.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
LOOOCGKK_00390 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
LOOOCGKK_00392 3.7e-09
LOOOCGKK_00393 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LOOOCGKK_00394 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
LOOOCGKK_00395 2.3e-23 L Transposase
LOOOCGKK_00396 4.6e-25 tatA U protein secretion
LOOOCGKK_00397 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LOOOCGKK_00398 5.7e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
LOOOCGKK_00399 1.5e-233 ycdB P peroxidase
LOOOCGKK_00400 2.1e-152 ycdO P periplasmic lipoprotein involved in iron transport
LOOOCGKK_00401 2.2e-177 fatB P ABC-type enterochelin transport system, periplasmic component
LOOOCGKK_00402 2e-135 yclP 3.6.3.34 P abc transporter atp-binding protein
LOOOCGKK_00403 1.9e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOOOCGKK_00404 4e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOOOCGKK_00405 2e-139 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LOOOCGKK_00406 3.8e-54 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LOOOCGKK_00407 7.3e-143 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LOOOCGKK_00408 1.9e-37 3.5.1.28 NU amidase activity
LOOOCGKK_00409 8.5e-266 3.5.1.28 NU amidase activity
LOOOCGKK_00410 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LOOOCGKK_00411 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LOOOCGKK_00412 0.0 lpdA 1.8.1.4 C Dehydrogenase
LOOOCGKK_00413 1.2e-199 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LOOOCGKK_00414 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LOOOCGKK_00415 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
LOOOCGKK_00416 5e-38 P membrane protein (DUF2207)
LOOOCGKK_00417 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
LOOOCGKK_00418 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LOOOCGKK_00419 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LOOOCGKK_00420 9.5e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LOOOCGKK_00421 1.2e-157 rssA S Phospholipase, patatin family
LOOOCGKK_00422 4.2e-33 estA E GDSL-like protein
LOOOCGKK_00423 9.7e-65 estA E Lysophospholipase L1 and related esterases
LOOOCGKK_00424 5e-290 S unusual protein kinase
LOOOCGKK_00425 4.9e-39 S granule-associated protein
LOOOCGKK_00426 1.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOOOCGKK_00427 3.9e-137 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOOOCGKK_00428 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOOOCGKK_00429 1.3e-199 S hmm pf01594
LOOOCGKK_00430 5.8e-86 G Belongs to the phosphoglycerate mutase family
LOOOCGKK_00431 1.3e-66 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
LOOOCGKK_00432 5.4e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LOOOCGKK_00433 4.8e-97 2.7.8.12 GT2 S Glycosyltransferase like family 2
LOOOCGKK_00434 1.1e-89 tnp L DDE domain
LOOOCGKK_00435 5e-162 L Transposase DDE domain
LOOOCGKK_00436 2.7e-23 rgpAc GT4 M group 1 family protein
LOOOCGKK_00437 2.7e-239 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
LOOOCGKK_00438 3.2e-114 cpsD D COG0489 ATPases involved in chromosome partitioning
LOOOCGKK_00439 5.5e-108 cps4C M biosynthesis protein
LOOOCGKK_00440 1.5e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
LOOOCGKK_00441 2.5e-227 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
LOOOCGKK_00442 9e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
LOOOCGKK_00443 2.4e-117 yfeJ 6.3.5.2 F glutamine amidotransferase
LOOOCGKK_00444 2.3e-55 clcA_2 P chloride
LOOOCGKK_00445 2.6e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LOOOCGKK_00446 1.6e-62 S Protein of unknown function (DUF1697)
LOOOCGKK_00447 1.4e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LOOOCGKK_00448 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LOOOCGKK_00451 1.5e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
LOOOCGKK_00452 5.3e-275 pepV 3.5.1.18 E Dipeptidase
LOOOCGKK_00453 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LOOOCGKK_00454 1.7e-47 XK27_03610 K Gnat family
LOOOCGKK_00455 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LOOOCGKK_00456 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LOOOCGKK_00457 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LOOOCGKK_00458 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LOOOCGKK_00459 3.9e-15 M LysM domain
LOOOCGKK_00460 2.9e-90 ebsA S Family of unknown function (DUF5322)
LOOOCGKK_00461 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LOOOCGKK_00462 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LOOOCGKK_00463 4.9e-224 G COG0457 FOG TPR repeat
LOOOCGKK_00464 1.1e-175 yubA S permease
LOOOCGKK_00465 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
LOOOCGKK_00466 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LOOOCGKK_00467 7.2e-124 ftsE D cell division ATP-binding protein FtsE
LOOOCGKK_00468 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LOOOCGKK_00469 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LOOOCGKK_00470 1.3e-181 yjjH S Calcineurin-like phosphoesterase
LOOOCGKK_00471 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LOOOCGKK_00472 0.0 pacL 3.6.3.8 P cation transport ATPase
LOOOCGKK_00473 2.6e-67 ywiB S Domain of unknown function (DUF1934)
LOOOCGKK_00474 8.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
LOOOCGKK_00475 4.6e-146 yidA S hydrolases of the HAD superfamily
LOOOCGKK_00476 2e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
LOOOCGKK_00477 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
LOOOCGKK_00478 3.9e-235 vicK 2.7.13.3 T Histidine kinase
LOOOCGKK_00479 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOOOCGKK_00480 4.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
LOOOCGKK_00481 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LOOOCGKK_00482 5.9e-118 gltJ P ABC transporter (Permease
LOOOCGKK_00483 1.7e-111 tcyB_2 P ABC transporter (permease)
LOOOCGKK_00484 2.4e-124 endA F DNA RNA non-specific endonuclease
LOOOCGKK_00485 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
LOOOCGKK_00486 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LOOOCGKK_00488 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LOOOCGKK_00489 5.9e-26 G Domain of unknown function (DUF4832)
LOOOCGKK_00490 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LOOOCGKK_00491 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LOOOCGKK_00492 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LOOOCGKK_00493 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
LOOOCGKK_00494 1.1e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LOOOCGKK_00495 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
LOOOCGKK_00498 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LOOOCGKK_00499 6.3e-216 XK27_05110 P chloride
LOOOCGKK_00500 9.6e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
LOOOCGKK_00501 9.2e-281 clcA P Chloride transporter, ClC family
LOOOCGKK_00502 5.1e-75 fld C Flavodoxin
LOOOCGKK_00503 2.5e-14 XK27_08880
LOOOCGKK_00504 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
LOOOCGKK_00505 1.6e-151 estA CE1 S Putative esterase
LOOOCGKK_00506 7.8e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LOOOCGKK_00507 1.7e-134 XK27_08845 S abc transporter atp-binding protein
LOOOCGKK_00508 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
LOOOCGKK_00509 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
LOOOCGKK_00510 3.2e-17 S Domain of unknown function (DUF4649)
LOOOCGKK_00512 6.6e-42 Q the current gene model (or a revised gene model) may contain a frame shift
LOOOCGKK_00513 6.3e-28 Q the current gene model (or a revised gene model) may contain a frame shift
LOOOCGKK_00515 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
LOOOCGKK_00517 3.5e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LOOOCGKK_00518 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LOOOCGKK_00519 0.0 dnaE 2.7.7.7 L DNA polymerase
LOOOCGKK_00520 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
LOOOCGKK_00521 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LOOOCGKK_00522 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LOOOCGKK_00523 2.5e-43 ysdA L Membrane
LOOOCGKK_00524 2.8e-188 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LOOOCGKK_00525 1e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LOOOCGKK_00526 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LOOOCGKK_00527 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
LOOOCGKK_00529 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LOOOCGKK_00530 1.3e-94 ypmS S Protein conserved in bacteria
LOOOCGKK_00531 3.2e-145 ypmR E lipolytic protein G-D-S-L family
LOOOCGKK_00532 1.7e-148 DegV S DegV family
LOOOCGKK_00533 3.8e-304 recN L May be involved in recombinational repair of damaged DNA
LOOOCGKK_00534 1.1e-72 argR K arginine binding
LOOOCGKK_00535 2.5e-158 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LOOOCGKK_00536 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LOOOCGKK_00537 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
LOOOCGKK_00538 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LOOOCGKK_00541 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LOOOCGKK_00542 2.9e-125 dnaD
LOOOCGKK_00543 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LOOOCGKK_00544 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LOOOCGKK_00545 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
LOOOCGKK_00546 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LOOOCGKK_00547 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LOOOCGKK_00548 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
LOOOCGKK_00549 7.8e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LOOOCGKK_00550 5.6e-240 rodA D Belongs to the SEDS family
LOOOCGKK_00551 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
LOOOCGKK_00552 1.2e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LOOOCGKK_00553 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LOOOCGKK_00554 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LOOOCGKK_00555 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LOOOCGKK_00556 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LOOOCGKK_00557 1.2e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LOOOCGKK_00558 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LOOOCGKK_00559 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LOOOCGKK_00560 4.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LOOOCGKK_00562 6.6e-31 L Integrase core domain protein
LOOOCGKK_00563 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LOOOCGKK_00564 7.9e-39 ptsH G phosphocarrier protein Hpr
LOOOCGKK_00565 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
LOOOCGKK_00566 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
LOOOCGKK_00567 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LOOOCGKK_00568 2.2e-34 nrdH O Glutaredoxin
LOOOCGKK_00569 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOOOCGKK_00570 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOOOCGKK_00572 4.2e-71 L Transposase (IS116 IS110 IS902 family)
LOOOCGKK_00573 8.8e-60 L Transposase (IS116 IS110 IS902 family)
LOOOCGKK_00574 5.3e-165 ypuA S secreted protein
LOOOCGKK_00575 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
LOOOCGKK_00576 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
LOOOCGKK_00577 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOOOCGKK_00578 3.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LOOOCGKK_00579 2.6e-258 noxE P NADH oxidase
LOOOCGKK_00580 2.8e-293 yfmM S abc transporter atp-binding protein
LOOOCGKK_00581 1e-56 XK27_01265 S ECF-type riboflavin transporter, S component
LOOOCGKK_00582 5.4e-09 XK27_01265 S ECF-type riboflavin transporter, S component
LOOOCGKK_00583 1.2e-94 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
LOOOCGKK_00584 2e-86 S ECF-type riboflavin transporter, S component
LOOOCGKK_00586 4.2e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOOOCGKK_00587 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
LOOOCGKK_00590 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LOOOCGKK_00591 4.1e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOOOCGKK_00592 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LOOOCGKK_00593 0.0 smc D Required for chromosome condensation and partitioning
LOOOCGKK_00594 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LOOOCGKK_00595 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LOOOCGKK_00596 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LOOOCGKK_00597 1.2e-88 alkD L Dna alkylation repair
LOOOCGKK_00598 2.4e-92 pat 2.3.1.183 M acetyltransferase
LOOOCGKK_00599 1.5e-12
LOOOCGKK_00600 3.1e-30
LOOOCGKK_00601 2.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOOOCGKK_00602 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LOOOCGKK_00603 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
LOOOCGKK_00604 1.2e-62 bioY S biotin transmembrane transporter activity
LOOOCGKK_00605 2.2e-87 proW P Binding-protein-dependent transport system inner membrane component
LOOOCGKK_00606 1.5e-138 proV E abc transporter atp-binding protein
LOOOCGKK_00607 7.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
LOOOCGKK_00608 3e-111 proWZ P ABC transporter (Permease
LOOOCGKK_00609 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
LOOOCGKK_00610 1.6e-205 S Protein of unknown function (DUF917)
LOOOCGKK_00611 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LOOOCGKK_00612 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
LOOOCGKK_00613 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOOOCGKK_00614 1.5e-192 desK 2.7.13.3 T Histidine kinase
LOOOCGKK_00615 1.4e-133 yvfS V ABC-2 type transporter
LOOOCGKK_00616 8.7e-159 XK27_09825 V abc transporter atp-binding protein
LOOOCGKK_00620 6.6e-213 EGP Major facilitator Superfamily
LOOOCGKK_00621 1.6e-307 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
LOOOCGKK_00622 4.6e-152 mutR K Transcriptional activator, Rgg GadR MutR family
LOOOCGKK_00623 4.6e-42 3.6.1.55 F NUDIX domain
LOOOCGKK_00624 3.9e-223 L Transposase
LOOOCGKK_00626 3.7e-122 S An automated process has identified a potential problem with this gene model
LOOOCGKK_00627 1.9e-24 XK27_09825 V 'abc transporter, ATP-binding protein
LOOOCGKK_00628 1.5e-11 liaI KT membrane
LOOOCGKK_00629 2.6e-30 liaI KT membrane
LOOOCGKK_00630 1.3e-50 XK27_05000 S Fe-S-cluster oxidoreductase
LOOOCGKK_00631 2e-32 XK27_05000 S Fe-S-cluster oxidoreductase
LOOOCGKK_00632 0.0 V ABC transporter (permease)
LOOOCGKK_00633 1.9e-133 macB2 V ABC transporter, ATP-binding protein
LOOOCGKK_00634 6.2e-166 T Histidine kinase
LOOOCGKK_00635 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOOOCGKK_00636 5.9e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LOOOCGKK_00637 5e-194 pbuX F xanthine permease
LOOOCGKK_00638 1.7e-246 norM V Multidrug efflux pump
LOOOCGKK_00639 4.1e-186 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LOOOCGKK_00640 2.6e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
LOOOCGKK_00641 1e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
LOOOCGKK_00642 7.3e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
LOOOCGKK_00643 4.1e-63 yxeN U ABC transporter, permease protein
LOOOCGKK_00644 5.4e-58 yxeL K Acetyltransferase (GNAT) domain
LOOOCGKK_00645 8.8e-115 yxeQ S MmgE/PrpD family
LOOOCGKK_00646 1.1e-148 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
LOOOCGKK_00647 3.3e-102 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
LOOOCGKK_00648 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
LOOOCGKK_00649 6.6e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LOOOCGKK_00650 1.2e-233 brnQ E Component of the transport system for branched-chain amino acids
LOOOCGKK_00651 1.9e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
LOOOCGKK_00652 1.7e-45 manA 5.3.1.8 G mannose-6-phosphate isomerase
LOOOCGKK_00653 9.6e-26 csbD K CsbD-like
LOOOCGKK_00654 5.3e-227 yfnA E amino acid
LOOOCGKK_00655 5.7e-109 XK27_02070 S nitroreductase
LOOOCGKK_00656 6.2e-151 1.13.11.2 S glyoxalase
LOOOCGKK_00657 5.6e-77 ywnA K Transcriptional regulator
LOOOCGKK_00658 2.8e-157 E Alpha/beta hydrolase of unknown function (DUF915)
LOOOCGKK_00659 6e-233 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOOOCGKK_00660 1.4e-110 drgA C Nitroreductase
LOOOCGKK_00661 3e-102 yoaK S Protein of unknown function (DUF1275)
LOOOCGKK_00662 6.8e-161 yvgN C reductase
LOOOCGKK_00663 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LOOOCGKK_00664 2.3e-281 XK27_07020 S Belongs to the UPF0371 family
LOOOCGKK_00666 1.1e-37 BP1961 P nitric oxide dioxygenase activity
LOOOCGKK_00667 3.8e-28 K response regulator
LOOOCGKK_00668 7.2e-16 KT the current gene model (or a revised gene model) may contain a frame shift
LOOOCGKK_00669 9.3e-72 S Signal peptide protein, YSIRK family
LOOOCGKK_00671 2.5e-52
LOOOCGKK_00672 1.6e-266 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOOOCGKK_00673 1e-137
LOOOCGKK_00674 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
LOOOCGKK_00675 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
LOOOCGKK_00676 5.8e-109 MA20_06410 E LysE type translocator
LOOOCGKK_00677 5.6e-08
LOOOCGKK_00678 2.7e-09
LOOOCGKK_00679 0.0 M family 8
LOOOCGKK_00681 1.1e-151 V MatE
LOOOCGKK_00683 3.9e-110 C Fe-S oxidoreductases
LOOOCGKK_00684 1.5e-69 EGP Major Facilitator Superfamily
LOOOCGKK_00685 5.5e-258 I radical SAM domain protein
LOOOCGKK_00687 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LOOOCGKK_00688 1.4e-150 L Integrase core domain protein
LOOOCGKK_00689 1.8e-87 L transposase activity
LOOOCGKK_00691 1.4e-84
LOOOCGKK_00692 0.0 sbcC L ATPase involved in DNA repair
LOOOCGKK_00693 1.3e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LOOOCGKK_00694 0.0 lacL 3.2.1.23 G -beta-galactosidase
LOOOCGKK_00695 0.0 lacS G transporter
LOOOCGKK_00696 2.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LOOOCGKK_00697 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LOOOCGKK_00698 1.3e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
LOOOCGKK_00699 3.7e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LOOOCGKK_00700 2.3e-184 galR K Transcriptional regulator
LOOOCGKK_00701 2.7e-08 L Integrase core domain protein
LOOOCGKK_00702 3.5e-25 L transposition
LOOOCGKK_00703 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
LOOOCGKK_00704 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
LOOOCGKK_00705 2.5e-101 V abc transporter atp-binding protein
LOOOCGKK_00706 1e-41 V (ABC) transporter
LOOOCGKK_00707 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
LOOOCGKK_00708 6.4e-62 L Transposase
LOOOCGKK_00709 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LOOOCGKK_00710 3.8e-50 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LOOOCGKK_00711 2.8e-123 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LOOOCGKK_00712 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LOOOCGKK_00713 2.7e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LOOOCGKK_00714 4.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LOOOCGKK_00715 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LOOOCGKK_00718 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOOOCGKK_00719 1.7e-174 vraS 2.7.13.3 T Histidine kinase
LOOOCGKK_00720 3.1e-119 yvqF KT membrane
LOOOCGKK_00721 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LOOOCGKK_00722 2e-132 stp 3.1.3.16 T phosphatase
LOOOCGKK_00723 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LOOOCGKK_00724 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LOOOCGKK_00725 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LOOOCGKK_00726 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
LOOOCGKK_00727 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LOOOCGKK_00728 2.7e-215 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LOOOCGKK_00729 6.9e-150 XK27_02985 S overlaps another CDS with the same product name
LOOOCGKK_00730 2.1e-148 supH S overlaps another CDS with the same product name
LOOOCGKK_00731 8.6e-63 yvoA_1 K Transcriptional
LOOOCGKK_00732 2.8e-120 skfE V abc transporter atp-binding protein
LOOOCGKK_00733 3.3e-133 V ATPase activity
LOOOCGKK_00734 4.3e-172 oppF P Belongs to the ABC transporter superfamily
LOOOCGKK_00735 2.2e-204 oppD P Belongs to the ABC transporter superfamily
LOOOCGKK_00736 4.9e-168 amiD P ABC transporter (Permease
LOOOCGKK_00737 2.1e-277 amiC P ABC transporter (Permease
LOOOCGKK_00738 0.0 amiA E ABC transporter, substrate-binding protein, family 5
LOOOCGKK_00739 4.6e-13 L Transposase
LOOOCGKK_00740 3.4e-149 L the current gene model (or a revised gene model) may contain a frame shift
LOOOCGKK_00741 0.0 amiA E ABC transporter, substrate-binding protein, family 5
LOOOCGKK_00742 8.1e-45 L Transposase
LOOOCGKK_00743 4.1e-158 L COG2801 Transposase and inactivated derivatives
LOOOCGKK_00744 1.2e-24 oppF P Belongs to the ABC transporter superfamily
LOOOCGKK_00745 5e-45 oppF P Belongs to the ABC transporter superfamily
LOOOCGKK_00746 1.4e-40 tatD L Hydrolase, tatd
LOOOCGKK_00747 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
LOOOCGKK_00748 1e-110 L Integrase core domain protein
LOOOCGKK_00749 1.1e-23 L transposase activity
LOOOCGKK_00750 8.9e-18 L transposase activity
LOOOCGKK_00751 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LOOOCGKK_00752 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LOOOCGKK_00753 4e-153 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LOOOCGKK_00754 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
LOOOCGKK_00755 1.5e-103 yjbK S Adenylate cyclase
LOOOCGKK_00756 1.1e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LOOOCGKK_00757 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
LOOOCGKK_00758 9e-59 XK27_04120 S Putative amino acid metabolism
LOOOCGKK_00759 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LOOOCGKK_00760 1.6e-131 puuD T peptidase C26
LOOOCGKK_00761 6.2e-120 radC E Belongs to the UPF0758 family
LOOOCGKK_00762 2.9e-272 rgpF M Rhamnan synthesis protein F
LOOOCGKK_00763 4.4e-222 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LOOOCGKK_00764 6.4e-140 rgpC GM Transport permease protein
LOOOCGKK_00765 4.8e-171 rgpB GT2 M Glycosyltransferase, group 2 family protein
LOOOCGKK_00766 4.7e-221 rgpA GT4 M Domain of unknown function (DUF1972)
LOOOCGKK_00767 1.4e-173 S Glucosyl transferase GtrII
LOOOCGKK_00768 1.8e-28 S Glucosyl transferase GtrII
LOOOCGKK_00769 4.8e-219 GT4 M transferase activity, transferring glycosyl groups
LOOOCGKK_00770 2e-217 M Psort location CytoplasmicMembrane, score
LOOOCGKK_00771 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
LOOOCGKK_00772 1.5e-149 2.4.1.60 S Glycosyltransferase group 2 family protein
LOOOCGKK_00773 4.6e-42 S Uncharacterized conserved protein (DUF2304)
LOOOCGKK_00774 7.7e-129 arnC M group 2 family protein
LOOOCGKK_00775 3.4e-180 cpsIaJ S Glycosyltransferase like family 2
LOOOCGKK_00776 6.7e-184 S Glycosyltransferase like family 2
LOOOCGKK_00777 4.7e-222 amrA S membrane protein involved in the export of O-antigen and teichoic acid
LOOOCGKK_00778 1e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LOOOCGKK_00779 1.2e-253 S Glucosyl transferase GtrII
LOOOCGKK_00780 9.5e-172 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
LOOOCGKK_00781 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
LOOOCGKK_00782 8.9e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LOOOCGKK_00783 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LOOOCGKK_00784 9.4e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LOOOCGKK_00785 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
LOOOCGKK_00786 2.8e-202 arcT 2.6.1.1 E Aminotransferase
LOOOCGKK_00787 4.2e-136 ET ABC transporter
LOOOCGKK_00788 2.8e-143 ET Belongs to the bacterial solute-binding protein 3 family
LOOOCGKK_00789 2.9e-84 mutT 3.6.1.55 F Nudix family
LOOOCGKK_00790 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LOOOCGKK_00792 1.2e-55 V CAAX protease self-immunity
LOOOCGKK_00793 7.6e-32 S CAAX amino terminal protease family protein
LOOOCGKK_00794 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
LOOOCGKK_00795 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
LOOOCGKK_00796 2.4e-16 XK27_00735
LOOOCGKK_00797 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LOOOCGKK_00799 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LOOOCGKK_00802 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
LOOOCGKK_00803 6.6e-30 ycaO O OsmC-like protein
LOOOCGKK_00805 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
LOOOCGKK_00807 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
LOOOCGKK_00808 6.4e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LOOOCGKK_00809 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LOOOCGKK_00810 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LOOOCGKK_00811 7.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
LOOOCGKK_00812 2.8e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LOOOCGKK_00813 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOOOCGKK_00814 2.6e-109 3.1.3.18 S IA, variant 1
LOOOCGKK_00815 6.1e-112 lrgB M effector of murein hydrolase
LOOOCGKK_00816 2.2e-58 lrgA S Effector of murein hydrolase LrgA
LOOOCGKK_00818 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
LOOOCGKK_00819 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
LOOOCGKK_00820 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOOOCGKK_00821 2.5e-103 wecD M Acetyltransferase GNAT family
LOOOCGKK_00822 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LOOOCGKK_00823 2.6e-95 GK ROK family
LOOOCGKK_00824 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
LOOOCGKK_00825 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
LOOOCGKK_00826 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
LOOOCGKK_00827 2.3e-206 potD P spermidine putrescine ABC transporter
LOOOCGKK_00828 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
LOOOCGKK_00829 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
LOOOCGKK_00830 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LOOOCGKK_00831 7.8e-171 murB 1.3.1.98 M cell wall formation
LOOOCGKK_00832 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LOOOCGKK_00833 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LOOOCGKK_00834 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
LOOOCGKK_00835 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LOOOCGKK_00836 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
LOOOCGKK_00837 0.0 ydaO E amino acid
LOOOCGKK_00838 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LOOOCGKK_00839 4.1e-37 ylqC L Belongs to the UPF0109 family
LOOOCGKK_00840 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LOOOCGKK_00841 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
LOOOCGKK_00842 2.6e-157 xth 3.1.11.2 L exodeoxyribonuclease III
LOOOCGKK_00843 2.1e-74 S QueT transporter
LOOOCGKK_00844 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
LOOOCGKK_00845 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
LOOOCGKK_00846 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LOOOCGKK_00847 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LOOOCGKK_00848 3.7e-85 ccl S cog cog4708
LOOOCGKK_00849 7.4e-164 rbn E Belongs to the UPF0761 family
LOOOCGKK_00850 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
LOOOCGKK_00851 3.3e-231 ytoI K transcriptional regulator containing CBS domains
LOOOCGKK_00852 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
LOOOCGKK_00853 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LOOOCGKK_00854 0.0 comEC S Competence protein ComEC
LOOOCGKK_00855 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
LOOOCGKK_00856 8.3e-142 plsC 2.3.1.51 I Acyltransferase
LOOOCGKK_00857 1.7e-77 nodB3 G polysaccharide deacetylase
LOOOCGKK_00858 4.1e-22 nodB3 G polysaccharide deacetylase
LOOOCGKK_00859 2.3e-139 yabB 2.1.1.223 L Methyltransferase
LOOOCGKK_00860 1e-41 yazA L endonuclease containing a URI domain
LOOOCGKK_00861 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LOOOCGKK_00862 2.3e-154 corA P CorA-like protein
LOOOCGKK_00863 1.9e-62 yjqA S Bacterial PH domain
LOOOCGKK_00864 7.8e-100 thiT S Thiamine transporter
LOOOCGKK_00865 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LOOOCGKK_00866 1.9e-201 yjbB G Permeases of the major facilitator superfamily
LOOOCGKK_00867 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LOOOCGKK_00868 7.9e-120 ywaF S Integral membrane protein (intg_mem_TP0381)
LOOOCGKK_00869 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LOOOCGKK_00873 2.5e-155 cjaA ET ABC transporter substrate-binding protein
LOOOCGKK_00874 4.9e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
LOOOCGKK_00875 7.8e-107 P ABC transporter (Permease
LOOOCGKK_00876 6e-115 papP P ABC transporter (Permease
LOOOCGKK_00877 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LOOOCGKK_00878 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
LOOOCGKK_00879 0.0 copA 3.6.3.54 P P-type ATPase
LOOOCGKK_00880 8e-73 copY K Copper transport repressor, CopY TcrY family
LOOOCGKK_00881 4.3e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LOOOCGKK_00882 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LOOOCGKK_00883 6.1e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
LOOOCGKK_00884 7.9e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LOOOCGKK_00885 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LOOOCGKK_00886 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
LOOOCGKK_00887 1.5e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LOOOCGKK_00888 1.6e-55
LOOOCGKK_00889 0.0 ctpE P E1-E2 ATPase
LOOOCGKK_00890 3.9e-26
LOOOCGKK_00891 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LOOOCGKK_00892 9.7e-28 L transposase activity
LOOOCGKK_00893 2.7e-129 K transcriptional regulator, MerR family
LOOOCGKK_00894 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
LOOOCGKK_00895 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
LOOOCGKK_00896 7.4e-64 XK27_02560 S cog cog2151
LOOOCGKK_00897 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LOOOCGKK_00898 7.7e-227 ytfP S Flavoprotein
LOOOCGKK_00900 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LOOOCGKK_00901 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
LOOOCGKK_00902 1.6e-183 ecsB U ABC transporter
LOOOCGKK_00903 2.3e-133 ecsA V abc transporter atp-binding protein
LOOOCGKK_00904 5e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LOOOCGKK_00905 4.8e-11
LOOOCGKK_00906 6.5e-55
LOOOCGKK_00907 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
LOOOCGKK_00908 6.9e-206 ylbM S Belongs to the UPF0348 family
LOOOCGKK_00909 2e-140 yqeM Q Methyltransferase domain protein
LOOOCGKK_00910 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LOOOCGKK_00911 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LOOOCGKK_00912 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LOOOCGKK_00913 3.5e-49 yhbY J RNA-binding protein
LOOOCGKK_00914 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LOOOCGKK_00915 1.8e-98 yqeG S hydrolase of the HAD superfamily
LOOOCGKK_00916 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LOOOCGKK_00917 1.3e-57
LOOOCGKK_00918 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LOOOCGKK_00919 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LOOOCGKK_00920 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LOOOCGKK_00921 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
LOOOCGKK_00922 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOOOCGKK_00923 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOOOCGKK_00924 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LOOOCGKK_00925 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
LOOOCGKK_00926 6.8e-101 pncA Q isochorismatase
LOOOCGKK_00927 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LOOOCGKK_00928 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
LOOOCGKK_00929 2.4e-75 XK27_03180 T universal stress protein
LOOOCGKK_00932 7.4e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LOOOCGKK_00933 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
LOOOCGKK_00934 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
LOOOCGKK_00935 0.0 yjcE P NhaP-type Na H and K H antiporters
LOOOCGKK_00937 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
LOOOCGKK_00938 1.1e-183 yhcC S radical SAM protein
LOOOCGKK_00939 2.2e-196 ylbL T Belongs to the peptidase S16 family
LOOOCGKK_00940 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LOOOCGKK_00941 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
LOOOCGKK_00942 3.2e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LOOOCGKK_00943 1.9e-09 S Protein of unknown function (DUF4059)
LOOOCGKK_00944 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
LOOOCGKK_00945 1e-162 yxeN P ABC transporter (Permease
LOOOCGKK_00946 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LOOOCGKK_00948 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOOOCGKK_00949 0.0 pflB 2.3.1.54 C formate acetyltransferase'
LOOOCGKK_00950 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
LOOOCGKK_00951 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOOOCGKK_00952 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
LOOOCGKK_00953 2.9e-87 D nuclear chromosome segregation
LOOOCGKK_00954 1.5e-127 ybbM S transport system, permease component
LOOOCGKK_00955 1.2e-117 ybbL S abc transporter atp-binding protein
LOOOCGKK_00956 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
LOOOCGKK_00957 4.6e-140 cppA E CppA N-terminal
LOOOCGKK_00958 5e-44 V CAAX protease self-immunity
LOOOCGKK_00959 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
LOOOCGKK_00960 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LOOOCGKK_00963 3e-47 spiA K sequence-specific DNA binding
LOOOCGKK_00964 2.9e-28 blpT
LOOOCGKK_00965 6.7e-98 blpT
LOOOCGKK_00970 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
LOOOCGKK_00973 2.6e-132 agrA KT phosphorelay signal transduction system
LOOOCGKK_00974 3e-235 blpH 2.7.13.3 T protein histidine kinase activity
LOOOCGKK_00976 4.7e-236 mesE M Transport protein ComB
LOOOCGKK_00977 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LOOOCGKK_00978 0.0 mdlB V abc transporter atp-binding protein
LOOOCGKK_00979 0.0 mdlA V abc transporter atp-binding protein
LOOOCGKK_00981 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
LOOOCGKK_00982 8.7e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LOOOCGKK_00983 2.3e-72 yutD J protein conserved in bacteria
LOOOCGKK_00984 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LOOOCGKK_00986 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LOOOCGKK_00987 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LOOOCGKK_00988 0.0 ftsI 3.4.16.4 M penicillin-binding protein
LOOOCGKK_00989 8.1e-46 ftsL D cell division protein FtsL
LOOOCGKK_00990 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LOOOCGKK_00991 3e-128
LOOOCGKK_00992 9.7e-32 yhaI J Protein of unknown function (DUF805)
LOOOCGKK_00993 1.1e-12 D nuclear chromosome segregation
LOOOCGKK_00994 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LOOOCGKK_00995 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LOOOCGKK_00996 2.2e-285 XK27_00765
LOOOCGKK_00997 8.1e-134 ecsA_2 V abc transporter atp-binding protein
LOOOCGKK_00998 5.2e-125 S Protein of unknown function (DUF554)
LOOOCGKK_00999 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LOOOCGKK_01000 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LOOOCGKK_01001 9.8e-57 liaI S membrane
LOOOCGKK_01002 7e-10 XK27_02470 K LytTr DNA-binding domain protein
LOOOCGKK_01003 1.8e-65 KT response to antibiotic
LOOOCGKK_01004 5.2e-81 yebC M Membrane
LOOOCGKK_01005 2.9e-18 yebC M Membrane
LOOOCGKK_01006 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
LOOOCGKK_01007 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LOOOCGKK_01008 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LOOOCGKK_01009 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LOOOCGKK_01010 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LOOOCGKK_01011 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LOOOCGKK_01012 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LOOOCGKK_01013 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LOOOCGKK_01015 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
LOOOCGKK_01016 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
LOOOCGKK_01017 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
LOOOCGKK_01018 2.1e-290 scrB 3.2.1.26 GH32 G invertase
LOOOCGKK_01019 7.5e-180 scrR K Transcriptional
LOOOCGKK_01020 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LOOOCGKK_01021 3.4e-62 yqhY S protein conserved in bacteria
LOOOCGKK_01022 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LOOOCGKK_01023 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
LOOOCGKK_01024 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
LOOOCGKK_01026 8e-44 V 'abc transporter, ATP-binding protein
LOOOCGKK_01027 1e-58 V 'abc transporter, ATP-binding protein
LOOOCGKK_01029 1.9e-07
LOOOCGKK_01034 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LOOOCGKK_01035 4.7e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LOOOCGKK_01036 5.5e-36 XK27_02060 S Transglycosylase associated protein
LOOOCGKK_01037 2.6e-55 badR K DNA-binding transcription factor activity
LOOOCGKK_01038 3.5e-97 S reductase
LOOOCGKK_01039 6.9e-89 L Integrase core domain protein
LOOOCGKK_01040 6.4e-41 L transposition
LOOOCGKK_01042 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
LOOOCGKK_01043 7.1e-80 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LOOOCGKK_01045 6.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
LOOOCGKK_01046 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LOOOCGKK_01047 1.1e-83 S Putative small multi-drug export protein
LOOOCGKK_01048 6.2e-76 ctsR K Belongs to the CtsR family
LOOOCGKK_01049 0.0 clpC O Belongs to the ClpA ClpB family
LOOOCGKK_01050 8.1e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LOOOCGKK_01051 8.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LOOOCGKK_01052 1e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LOOOCGKK_01053 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LOOOCGKK_01054 4.5e-143 S SseB protein N-terminal domain
LOOOCGKK_01055 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
LOOOCGKK_01056 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LOOOCGKK_01057 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LOOOCGKK_01060 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOOOCGKK_01061 7.8e-85 yacP S RNA-binding protein containing a PIN domain
LOOOCGKK_01062 3.7e-154 degV S DegV family
LOOOCGKK_01063 1.8e-31 K helix-turn-helix
LOOOCGKK_01064 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LOOOCGKK_01065 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LOOOCGKK_01066 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
LOOOCGKK_01067 5.5e-111 int L Belongs to the 'phage' integrase family
LOOOCGKK_01068 4.5e-83 int L Belongs to the 'phage' integrase family
LOOOCGKK_01069 8.7e-41 S Helix-turn-helix domain
LOOOCGKK_01070 7.2e-173
LOOOCGKK_01071 3.4e-75 isp2 S pathogenesis
LOOOCGKK_01072 5.7e-91 tnp L Transposase
LOOOCGKK_01073 4.8e-224 capA M Bacterial capsule synthesis protein
LOOOCGKK_01074 3.6e-39 gcvR T UPF0237 protein
LOOOCGKK_01075 1.9e-242 XK27_08635 S UPF0210 protein
LOOOCGKK_01076 2.2e-38 ais G alpha-ribazole phosphatase activity
LOOOCGKK_01077 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LOOOCGKK_01078 1.3e-102 acmA 3.2.1.17 NU amidase activity
LOOOCGKK_01079 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LOOOCGKK_01080 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LOOOCGKK_01081 4.9e-297 dnaK O Heat shock 70 kDa protein
LOOOCGKK_01082 9.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LOOOCGKK_01085 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LOOOCGKK_01086 2e-169 corA P COG0598 Mg2 and Co2 transporters
LOOOCGKK_01087 3.1e-124 XK27_01040 S Pfam PF06570
LOOOCGKK_01089 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LOOOCGKK_01090 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LOOOCGKK_01091 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
LOOOCGKK_01092 9.5e-42 XK27_05745
LOOOCGKK_01093 4.2e-230 mutY L A G-specific adenine glycosylase
LOOOCGKK_01097 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LOOOCGKK_01098 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LOOOCGKK_01099 1e-93 cvpA S toxin biosynthetic process
LOOOCGKK_01100 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LOOOCGKK_01101 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LOOOCGKK_01102 6.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LOOOCGKK_01103 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LOOOCGKK_01104 2e-47 azlD E branched-chain amino acid
LOOOCGKK_01105 3.8e-117 azlC E AzlC protein
LOOOCGKK_01106 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LOOOCGKK_01107 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LOOOCGKK_01108 8.1e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
LOOOCGKK_01109 2.5e-33 ykzG S Belongs to the UPF0356 family
LOOOCGKK_01110 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LOOOCGKK_01111 2.7e-40 pscB M CHAP domain protein
LOOOCGKK_01112 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
LOOOCGKK_01113 8.5e-63 glnR K Transcriptional regulator
LOOOCGKK_01114 1.3e-87 S Fusaric acid resistance protein-like
LOOOCGKK_01115 1.1e-12
LOOOCGKK_01116 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LOOOCGKK_01117 3.2e-42 L Transposase
LOOOCGKK_01118 1.9e-46 L transposase activity
LOOOCGKK_01119 8.2e-22 L Transposase
LOOOCGKK_01120 1.8e-56 L transposition
LOOOCGKK_01121 9.1e-83 L Integrase core domain protein
LOOOCGKK_01122 2.2e-224 L Helix-turn-helix domain of transposase family ISL3
LOOOCGKK_01123 5.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LOOOCGKK_01124 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LOOOCGKK_01125 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LOOOCGKK_01126 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LOOOCGKK_01127 2.6e-141 purR 2.4.2.7 F operon repressor
LOOOCGKK_01128 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
LOOOCGKK_01129 6.9e-173 rmuC S RmuC domain protein
LOOOCGKK_01130 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
LOOOCGKK_01131 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LOOOCGKK_01132 4.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LOOOCGKK_01134 6.2e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LOOOCGKK_01135 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LOOOCGKK_01136 1.6e-143 tatD L Hydrolase, tatd
LOOOCGKK_01137 7.2e-74 yccU S CoA-binding protein
LOOOCGKK_01138 4.8e-51 trxA O Belongs to the thioredoxin family
LOOOCGKK_01139 1.9e-141 S Macro domain protein
LOOOCGKK_01140 2e-09 L thioesterase
LOOOCGKK_01141 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
LOOOCGKK_01144 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LOOOCGKK_01145 1e-13 rpmH J Ribosomal protein L34
LOOOCGKK_01146 2e-186 jag S RNA-binding protein
LOOOCGKK_01147 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LOOOCGKK_01148 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LOOOCGKK_01149 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
LOOOCGKK_01150 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LOOOCGKK_01151 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LOOOCGKK_01152 2e-80 amiA E transmembrane transport
LOOOCGKK_01153 3.8e-174 amiA E ABC transporter, substrate-binding protein, family 5
LOOOCGKK_01154 3.9e-27 amiA E ABC transporter, substrate-binding protein, family 5
LOOOCGKK_01155 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LOOOCGKK_01156 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LOOOCGKK_01157 9.2e-51 S Protein of unknown function (DUF3397)
LOOOCGKK_01158 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
LOOOCGKK_01159 2.1e-35 WQ51_05710 S Mitochondrial biogenesis AIM24
LOOOCGKK_01160 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
LOOOCGKK_01161 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LOOOCGKK_01162 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
LOOOCGKK_01163 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
LOOOCGKK_01164 1.1e-75 XK27_09620 S reductase
LOOOCGKK_01165 9.5e-214 XK27_09615 C reductase
LOOOCGKK_01166 2.1e-115 fnt P Formate nitrite transporter
LOOOCGKK_01167 2.1e-63 XK27_08585 S Psort location CytoplasmicMembrane, score
LOOOCGKK_01168 1.7e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LOOOCGKK_01169 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LOOOCGKK_01170 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
LOOOCGKK_01171 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LOOOCGKK_01172 6.7e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LOOOCGKK_01173 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LOOOCGKK_01174 1.9e-46 S glycolate biosynthetic process
LOOOCGKK_01175 1.5e-64 S phosphatase activity
LOOOCGKK_01176 4.1e-158 rrmA 2.1.1.187 Q methyltransferase
LOOOCGKK_01179 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LOOOCGKK_01180 1.5e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LOOOCGKK_01181 6.4e-37 yeeD O sulfur carrier activity
LOOOCGKK_01182 1.5e-186 yeeE S Sulphur transport
LOOOCGKK_01183 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LOOOCGKK_01184 3.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LOOOCGKK_01185 1.2e-08 S Domain of unknown function (DUF4651)
LOOOCGKK_01186 4.4e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LOOOCGKK_01187 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LOOOCGKK_01188 2.1e-109 S CAAX amino terminal protease family protein
LOOOCGKK_01190 1.7e-67 V CAAX protease self-immunity
LOOOCGKK_01191 8.8e-27 lanR K sequence-specific DNA binding
LOOOCGKK_01192 8.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LOOOCGKK_01193 2.9e-176 ytxK 2.1.1.72 L DNA methylase
LOOOCGKK_01194 5.2e-13 comGF U Putative Competence protein ComGF
LOOOCGKK_01195 1.3e-70 comGF U Competence protein ComGF
LOOOCGKK_01196 3.2e-15 NU Type II secretory pathway pseudopilin
LOOOCGKK_01197 3e-57 cglD NU Competence protein
LOOOCGKK_01198 8.5e-43 comGC U Required for transformation and DNA binding
LOOOCGKK_01199 5.4e-153 cglB U protein transport across the cell outer membrane
LOOOCGKK_01200 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LOOOCGKK_01201 2.9e-68 S cog cog4699
LOOOCGKK_01202 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOOOCGKK_01203 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOOOCGKK_01204 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LOOOCGKK_01205 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LOOOCGKK_01206 1.5e-194 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LOOOCGKK_01207 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
LOOOCGKK_01208 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
LOOOCGKK_01209 1e-145 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LOOOCGKK_01210 1.6e-121 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LOOOCGKK_01211 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LOOOCGKK_01212 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
LOOOCGKK_01213 1.8e-57 asp S cog cog1302
LOOOCGKK_01214 3.2e-226 norN V Mate efflux family protein
LOOOCGKK_01215 1.2e-277 thrC 4.2.3.1 E Threonine synthase
LOOOCGKK_01216 6.1e-64 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LOOOCGKK_01217 4.1e-22 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LOOOCGKK_01218 7.3e-74 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LOOOCGKK_01219 1.2e-133 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LOOOCGKK_01220 2.1e-52 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
LOOOCGKK_01221 0.0 pepO 3.4.24.71 O Peptidase family M13
LOOOCGKK_01222 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LOOOCGKK_01223 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LOOOCGKK_01224 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LOOOCGKK_01225 1.4e-54 treB 2.7.1.201 G PTS System
LOOOCGKK_01226 5.8e-21 treR K DNA-binding transcription factor activity
LOOOCGKK_01227 1.2e-85 treR K trehalose operon
LOOOCGKK_01228 3.3e-95 ywlG S Belongs to the UPF0340 family
LOOOCGKK_01231 2e-35 L PFAM Integrase, catalytic core
LOOOCGKK_01232 2e-94 L PFAM Integrase, catalytic core
LOOOCGKK_01233 3.3e-46 K Putative DNA-binding domain
LOOOCGKK_01234 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
LOOOCGKK_01239 1e-39
LOOOCGKK_01240 6.5e-31
LOOOCGKK_01241 5e-31 S Hypothetical protein (DUF2513)
LOOOCGKK_01242 7.7e-13
LOOOCGKK_01244 5.7e-217 S MvaI/BcnI restriction endonuclease family
LOOOCGKK_01246 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
LOOOCGKK_01247 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
LOOOCGKK_01249 9.5e-65 6.3.2.2 H ergothioneine biosynthetic process
LOOOCGKK_01250 1.6e-34 6.3.2.2 H ergothioneine biosynthetic process
LOOOCGKK_01251 7.9e-19 6.3.2.2 H gamma-glutamylcysteine synthetase
LOOOCGKK_01252 1.2e-11 6.3.2.2 H gamma-glutamylcysteine synthetase
LOOOCGKK_01253 3.3e-09 L PFAM Integrase, catalytic core
LOOOCGKK_01254 1.8e-111 L PFAM Integrase, catalytic core
LOOOCGKK_01255 3.3e-62 rplQ J ribosomal protein l17
LOOOCGKK_01256 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOOOCGKK_01257 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LOOOCGKK_01258 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LOOOCGKK_01259 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LOOOCGKK_01260 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LOOOCGKK_01261 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LOOOCGKK_01262 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LOOOCGKK_01263 4.4e-58 rplO J binds to the 23S rRNA
LOOOCGKK_01264 2.5e-23 rpmD J ribosomal protein l30
LOOOCGKK_01265 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LOOOCGKK_01266 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LOOOCGKK_01267 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LOOOCGKK_01268 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LOOOCGKK_01269 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LOOOCGKK_01270 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LOOOCGKK_01271 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LOOOCGKK_01272 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LOOOCGKK_01273 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LOOOCGKK_01274 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
LOOOCGKK_01275 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LOOOCGKK_01276 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LOOOCGKK_01277 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LOOOCGKK_01278 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LOOOCGKK_01279 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LOOOCGKK_01280 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LOOOCGKK_01281 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
LOOOCGKK_01282 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LOOOCGKK_01283 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
LOOOCGKK_01284 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LOOOCGKK_01285 0.0 XK27_09800 I Acyltransferase
LOOOCGKK_01286 1.7e-35 XK27_09805 S MORN repeat protein
LOOOCGKK_01287 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LOOOCGKK_01288 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LOOOCGKK_01289 1.5e-89 adk 2.7.4.3 F topology modulation protein
LOOOCGKK_01290 3.3e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LOOOCGKK_01291 7e-127 Z012_04635 K sequence-specific DNA binding
LOOOCGKK_01293 6.3e-16 C Radical SAM
LOOOCGKK_01294 3.4e-191 C Radical SAM
LOOOCGKK_01295 3.9e-287 V ABC transporter transmembrane region
LOOOCGKK_01296 2.5e-89 K sequence-specific DNA binding
LOOOCGKK_01297 1e-36 L Replication initiation factor
LOOOCGKK_01298 1.4e-107 L Replication initiation factor
LOOOCGKK_01299 1.9e-18 S Domain of unknown function (DUF3173)
LOOOCGKK_01300 3.5e-216 int L Belongs to the 'phage' integrase family
LOOOCGKK_01302 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
LOOOCGKK_01303 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LOOOCGKK_01304 1.1e-43 yrzL S Belongs to the UPF0297 family
LOOOCGKK_01305 9.5e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LOOOCGKK_01306 1.3e-45 yrzB S Belongs to the UPF0473 family
LOOOCGKK_01307 1.1e-292 ccs S the current gene model (or a revised gene model) may contain a frame shift
LOOOCGKK_01308 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LOOOCGKK_01309 7.5e-14
LOOOCGKK_01310 3.4e-91 XK27_10930 K acetyltransferase
LOOOCGKK_01311 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LOOOCGKK_01312 1.8e-147 yaaA S Belongs to the UPF0246 family
LOOOCGKK_01313 9.3e-167 XK27_01785 S cog cog1284
LOOOCGKK_01314 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LOOOCGKK_01316 2.1e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
LOOOCGKK_01317 1.9e-135 metE 2.1.1.14 E Methionine synthase
LOOOCGKK_01318 1.8e-30 metE 2.1.1.14 E Methionine synthase
LOOOCGKK_01319 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LOOOCGKK_01320 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LOOOCGKK_01321 2.4e-28
LOOOCGKK_01322 0.0 V Type II restriction enzyme, methylase subunits
LOOOCGKK_01323 3.2e-10 S Sigma-70, region 4
LOOOCGKK_01324 1.7e-35
LOOOCGKK_01325 5.7e-160 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LOOOCGKK_01326 2e-20
LOOOCGKK_01327 2.1e-82 S Plasmid replication protein
LOOOCGKK_01328 5.9e-20 S MerR HTH family regulatory protein
LOOOCGKK_01329 5.1e-184 sip L Belongs to the 'phage' integrase family
LOOOCGKK_01332 1.2e-48 yegS 2.7.1.107 I Diacylglycerol kinase
LOOOCGKK_01333 2.1e-95 S Hydrophobic domain protein
LOOOCGKK_01335 3e-29 S Membrane
LOOOCGKK_01336 8.8e-85
LOOOCGKK_01337 1.8e-23 S Small integral membrane protein
LOOOCGKK_01338 1.1e-85 M Protein conserved in bacteria
LOOOCGKK_01339 9.2e-11 K CsbD-like
LOOOCGKK_01340 5.5e-08 nudL L hydrolase
LOOOCGKK_01341 4e-19 K negative regulation of transcription, DNA-templated
LOOOCGKK_01342 1.7e-23 K negative regulation of transcription, DNA-templated
LOOOCGKK_01344 1.2e-18 XK27_06920 S Protein of unknown function (DUF1700)
LOOOCGKK_01345 9.3e-57 S Putative adhesin
LOOOCGKK_01346 9.8e-23 S Putative adhesin
LOOOCGKK_01347 1.2e-159 XK27_06930 V domain protein
LOOOCGKK_01348 6.4e-96 XK27_06935 K transcriptional regulator
LOOOCGKK_01349 4.8e-55 ypaA M Membrane
LOOOCGKK_01350 2.7e-08
LOOOCGKK_01351 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LOOOCGKK_01352 8.2e-48 veg S Biofilm formation stimulator VEG
LOOOCGKK_01353 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LOOOCGKK_01354 3.9e-70 rplI J binds to the 23S rRNA
LOOOCGKK_01355 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LOOOCGKK_01356 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LOOOCGKK_01357 1.5e-77 F NUDIX domain
LOOOCGKK_01358 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LOOOCGKK_01359 0.0 S Bacterial membrane protein, YfhO
LOOOCGKK_01360 3.4e-88 isaA GH23 M Immunodominant staphylococcal antigen A
LOOOCGKK_01361 5.3e-85 lytE M LysM domain protein
LOOOCGKK_01362 4.5e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOOOCGKK_01363 2e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOOOCGKK_01364 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOOOCGKK_01365 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LOOOCGKK_01366 6.3e-138 ymfM S sequence-specific DNA binding
LOOOCGKK_01367 1.2e-241 ymfH S Peptidase M16
LOOOCGKK_01368 1.3e-156 ymfF S Peptidase M16
LOOOCGKK_01369 1.5e-65 ymfF S Peptidase M16
LOOOCGKK_01370 1.6e-45 yaaA S S4 domain protein YaaA
LOOOCGKK_01371 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LOOOCGKK_01372 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LOOOCGKK_01373 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LOOOCGKK_01374 4.2e-153 yvjA S membrane
LOOOCGKK_01375 6.7e-306 ybiT S abc transporter atp-binding protein
LOOOCGKK_01376 0.0 XK27_10405 S Bacterial membrane protein YfhO
LOOOCGKK_01380 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
LOOOCGKK_01381 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LOOOCGKK_01382 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
LOOOCGKK_01383 8.5e-134 parB K Belongs to the ParB family
LOOOCGKK_01384 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LOOOCGKK_01385 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LOOOCGKK_01386 1.1e-29 yyzM S Protein conserved in bacteria
LOOOCGKK_01387 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LOOOCGKK_01388 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LOOOCGKK_01389 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LOOOCGKK_01390 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LOOOCGKK_01391 2.7e-61 divIC D Septum formation initiator
LOOOCGKK_01393 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
LOOOCGKK_01394 5.5e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LOOOCGKK_01395 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LOOOCGKK_01396 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LOOOCGKK_01397 3e-30
LOOOCGKK_01398 5.4e-133 L Transposase
LOOOCGKK_01399 1.9e-46 L transposase activity
LOOOCGKK_01400 5.7e-23 L Transposase
LOOOCGKK_01401 2.7e-28 L transposition
LOOOCGKK_01402 4.3e-96 L Transposase and inactivated derivatives
LOOOCGKK_01403 3.6e-157 L Transposase
LOOOCGKK_01404 1.7e-212 glf 5.4.99.9 M UDP-galactopyranose mutase
LOOOCGKK_01405 3e-216 epsU S Polysaccharide biosynthesis protein
LOOOCGKK_01406 6.2e-239 cps1C S Polysaccharide biosynthesis protein
LOOOCGKK_01407 2.5e-87 2.7.8.12 GT2 M Glycosyltransferase like family 2
LOOOCGKK_01408 3.6e-61 ywqD 2.7.10.1 D Capsular exopolysaccharide family
LOOOCGKK_01409 1.8e-101 M group 2 family protein
LOOOCGKK_01410 2.6e-100
LOOOCGKK_01412 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LOOOCGKK_01413 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
LOOOCGKK_01414 4.3e-41 L Protein of unknown function (DUF3991)
LOOOCGKK_01416 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LOOOCGKK_01417 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
LOOOCGKK_01418 1.7e-60 hmpT S membrane
LOOOCGKK_01419 1.2e-165 L integrase core domain
LOOOCGKK_01420 2e-52 L Transposase
LOOOCGKK_01421 1.1e-250 L Transposase
LOOOCGKK_01423 2.5e-169 L Transposase
LOOOCGKK_01424 9.9e-19 S Domain of unknown function (DUF4649)
LOOOCGKK_01425 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LOOOCGKK_01426 1.8e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LOOOCGKK_01427 1.9e-86
LOOOCGKK_01428 1.6e-77 sigH K DNA-templated transcription, initiation
LOOOCGKK_01429 3.5e-149 ykuT M mechanosensitive ion channel
LOOOCGKK_01430 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LOOOCGKK_01431 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LOOOCGKK_01432 2.9e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LOOOCGKK_01433 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
LOOOCGKK_01434 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
LOOOCGKK_01435 9.1e-178 prmA J Ribosomal protein L11 methyltransferase
LOOOCGKK_01436 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LOOOCGKK_01437 5.5e-30 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LOOOCGKK_01438 3.5e-63 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LOOOCGKK_01439 7.6e-46 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LOOOCGKK_01440 1.3e-186 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LOOOCGKK_01441 1.8e-83 nrdI F Belongs to the NrdI family
LOOOCGKK_01442 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LOOOCGKK_01443 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LOOOCGKK_01444 5.8e-08 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LOOOCGKK_01445 6.8e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LOOOCGKK_01446 2.3e-18 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LOOOCGKK_01447 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LOOOCGKK_01448 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LOOOCGKK_01449 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LOOOCGKK_01450 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LOOOCGKK_01451 6.5e-202 yhjX P Major Facilitator
LOOOCGKK_01452 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LOOOCGKK_01453 5e-94 V VanZ like family
LOOOCGKK_01454 1e-123 glnQ E abc transporter atp-binding protein
LOOOCGKK_01455 5.8e-275 glnP P ABC transporter
LOOOCGKK_01456 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LOOOCGKK_01457 1.5e-135 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LOOOCGKK_01458 7.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
LOOOCGKK_01459 1.1e-143 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LOOOCGKK_01460 1.4e-234 sufD O assembly protein SufD
LOOOCGKK_01461 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LOOOCGKK_01462 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
LOOOCGKK_01463 2.2e-273 sufB O assembly protein SufB
LOOOCGKK_01464 7e-10 oppA E ABC transporter substrate-binding protein
LOOOCGKK_01465 2e-138 oppA E ABC transporter substrate-binding protein
LOOOCGKK_01466 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOOOCGKK_01467 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOOOCGKK_01468 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOOOCGKK_01469 2.5e-09 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOOOCGKK_01470 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOOOCGKK_01471 3e-27 oppD P Belongs to the ABC transporter superfamily
LOOOCGKK_01472 2.5e-32 oppD P Belongs to the ABC transporter superfamily
LOOOCGKK_01473 1.2e-62 oppD P Belongs to the ABC transporter superfamily
LOOOCGKK_01474 1.2e-42 oppD P Belongs to the ABC transporter superfamily
LOOOCGKK_01475 7.5e-62 oppF P Belongs to the ABC transporter superfamily
LOOOCGKK_01476 3.4e-62 oppF P Belongs to the ABC transporter superfamily
LOOOCGKK_01477 8.3e-23
LOOOCGKK_01478 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LOOOCGKK_01479 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LOOOCGKK_01480 9.4e-223 EGP Major facilitator Superfamily
LOOOCGKK_01481 3.1e-72 adcR K transcriptional
LOOOCGKK_01482 2.2e-136 adcC P ABC transporter, ATP-binding protein
LOOOCGKK_01483 4.6e-130 adcB P ABC transporter (Permease
LOOOCGKK_01484 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
LOOOCGKK_01485 6.9e-28 ptsG 2.7.1.199, 2.7.1.208 G pts system
LOOOCGKK_01486 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
LOOOCGKK_01487 1.4e-105 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LOOOCGKK_01488 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
LOOOCGKK_01489 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
LOOOCGKK_01490 1.9e-127 yeeN K transcriptional regulatory protein
LOOOCGKK_01491 9.8e-50 yajC U protein transport
LOOOCGKK_01492 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LOOOCGKK_01493 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
LOOOCGKK_01494 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LOOOCGKK_01495 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LOOOCGKK_01496 0.0 WQ51_06230 S ABC transporter substrate binding protein
LOOOCGKK_01497 5.2e-142 cmpC S abc transporter atp-binding protein
LOOOCGKK_01498 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LOOOCGKK_01499 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LOOOCGKK_01500 4.4e-37 L Transposase
LOOOCGKK_01501 2.6e-19 L transposase activity
LOOOCGKK_01502 1.9e-50 L transposition
LOOOCGKK_01503 1.4e-33 L Integrase core domain protein
LOOOCGKK_01505 2e-41
LOOOCGKK_01506 1.7e-54 S TM2 domain
LOOOCGKK_01507 1.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LOOOCGKK_01508 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LOOOCGKK_01509 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
LOOOCGKK_01510 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
LOOOCGKK_01511 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
LOOOCGKK_01512 6e-55 cof Q phosphatase activity
LOOOCGKK_01513 6.2e-35 cof Q phosphatase activity
LOOOCGKK_01514 1.6e-137 glcR K transcriptional regulator (DeoR family)
LOOOCGKK_01515 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LOOOCGKK_01516 3.8e-40 K transcriptional
LOOOCGKK_01518 2.6e-76 S thiolester hydrolase activity
LOOOCGKK_01519 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
LOOOCGKK_01520 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LOOOCGKK_01521 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LOOOCGKK_01522 1.9e-77 yhaI L Membrane
LOOOCGKK_01523 1.9e-258 pepC 3.4.22.40 E aminopeptidase
LOOOCGKK_01524 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LOOOCGKK_01525 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LOOOCGKK_01526 3.1e-95 ypsA S Belongs to the UPF0398 family
LOOOCGKK_01527 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LOOOCGKK_01528 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LOOOCGKK_01529 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
LOOOCGKK_01530 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
LOOOCGKK_01531 2.5e-23
LOOOCGKK_01532 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LOOOCGKK_01533 7.3e-80 XK27_09675 K -acetyltransferase
LOOOCGKK_01534 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LOOOCGKK_01535 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LOOOCGKK_01536 5.2e-59 L Integrase core domain protein
LOOOCGKK_01537 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LOOOCGKK_01538 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LOOOCGKK_01539 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOOOCGKK_01540 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
LOOOCGKK_01541 8.8e-98 ybhL S Belongs to the BI1 family
LOOOCGKK_01544 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LOOOCGKK_01545 3.7e-91 K transcriptional regulator
LOOOCGKK_01546 7.6e-36 yneF S UPF0154 protein
LOOOCGKK_01547 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LOOOCGKK_01548 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LOOOCGKK_01549 3.5e-99 XK27_09740 S Phosphoesterase
LOOOCGKK_01550 7.8e-85 ykuL S CBS domain
LOOOCGKK_01551 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
LOOOCGKK_01552 4.5e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LOOOCGKK_01553 8.8e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LOOOCGKK_01554 1.3e-139 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LOOOCGKK_01555 8e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LOOOCGKK_01556 1.2e-258 trkH P Cation transport protein
LOOOCGKK_01557 1.5e-247 trkA P Potassium transporter peripheral membrane component
LOOOCGKK_01558 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LOOOCGKK_01559 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LOOOCGKK_01560 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
LOOOCGKK_01561 5.6e-161 K sequence-specific DNA binding
LOOOCGKK_01562 1.2e-32 V protein secretion by the type I secretion system
LOOOCGKK_01563 5.5e-105 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LOOOCGKK_01564 3.2e-75 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LOOOCGKK_01565 1.1e-85 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LOOOCGKK_01566 2.6e-47 yhaI L Membrane
LOOOCGKK_01567 1.5e-56 S Domain of unknown function (DUF4173)
LOOOCGKK_01568 3.4e-94 ureI S AmiS/UreI family transporter
LOOOCGKK_01569 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LOOOCGKK_01570 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LOOOCGKK_01571 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LOOOCGKK_01572 6.6e-78 ureE O enzyme active site formation
LOOOCGKK_01573 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LOOOCGKK_01574 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LOOOCGKK_01575 2.2e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LOOOCGKK_01576 1.1e-175 cbiM P PDGLE domain
LOOOCGKK_01577 1.1e-136 P cobalt transport protein
LOOOCGKK_01578 1.6e-131 cbiO P ABC transporter
LOOOCGKK_01579 5.3e-153 ET amino acid transport
LOOOCGKK_01580 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOOOCGKK_01581 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
LOOOCGKK_01582 3.8e-205 EGP Transmembrane secretion effector
LOOOCGKK_01583 1.3e-145 ET amino acid transport
LOOOCGKK_01584 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
LOOOCGKK_01585 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
LOOOCGKK_01586 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
LOOOCGKK_01587 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
LOOOCGKK_01588 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LOOOCGKK_01589 5.2e-98 metI P ABC transporter (Permease
LOOOCGKK_01590 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LOOOCGKK_01591 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
LOOOCGKK_01592 2.3e-93 S UPF0397 protein
LOOOCGKK_01593 0.0 ykoD P abc transporter atp-binding protein
LOOOCGKK_01594 1.2e-146 cbiQ P cobalt transport
LOOOCGKK_01595 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LOOOCGKK_01596 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
LOOOCGKK_01597 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
LOOOCGKK_01598 1.4e-243 P COG0168 Trk-type K transport systems, membrane components
LOOOCGKK_01599 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
LOOOCGKK_01600 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
LOOOCGKK_01601 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOOOCGKK_01602 2.8e-282 T PhoQ Sensor
LOOOCGKK_01603 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LOOOCGKK_01604 5e-218 dnaB L Replication initiation and membrane attachment
LOOOCGKK_01605 4e-167 dnaI L Primosomal protein DnaI
LOOOCGKK_01606 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LOOOCGKK_01607 9e-88 yrdC 3.5.1.19 Q isochorismatase
LOOOCGKK_01608 5.1e-85 L PFAM Integrase catalytic region
LOOOCGKK_01609 1.7e-54 L transposition
LOOOCGKK_01610 5e-23 L Transposase
LOOOCGKK_01611 2.3e-32 L transposase activity
LOOOCGKK_01612 1.3e-22 XK27_08085
LOOOCGKK_01613 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
LOOOCGKK_01614 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
LOOOCGKK_01615 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
LOOOCGKK_01616 1.1e-121 ylfI S tigr01906
LOOOCGKK_01617 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LOOOCGKK_01618 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
LOOOCGKK_01619 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
LOOOCGKK_01622 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LOOOCGKK_01623 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LOOOCGKK_01624 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LOOOCGKK_01625 1.1e-206 yurR 1.4.5.1 E oxidoreductase
LOOOCGKK_01626 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
LOOOCGKK_01627 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LOOOCGKK_01628 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
LOOOCGKK_01629 1.3e-70 gtrA S GtrA-like protein
LOOOCGKK_01630 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LOOOCGKK_01631 2.3e-168 ybbR S Protein conserved in bacteria
LOOOCGKK_01632 2.8e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LOOOCGKK_01633 1.1e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
LOOOCGKK_01634 8.7e-150 cobQ S glutamine amidotransferase
LOOOCGKK_01635 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LOOOCGKK_01636 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
LOOOCGKK_01637 6.3e-13 MA20_06245 S yiaA/B two helix domain
LOOOCGKK_01639 0.0 uup S abc transporter atp-binding protein
LOOOCGKK_01640 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
LOOOCGKK_01641 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
LOOOCGKK_01642 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LOOOCGKK_01643 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
LOOOCGKK_01644 5e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LOOOCGKK_01645 6.5e-63 manO S protein conserved in bacteria
LOOOCGKK_01646 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
LOOOCGKK_01647 1.3e-116 manM G pts system
LOOOCGKK_01648 1.1e-181 manL 2.7.1.191 G pts system
LOOOCGKK_01649 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
LOOOCGKK_01650 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LOOOCGKK_01651 2.1e-247 pbuO S permease
LOOOCGKK_01652 2.1e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
LOOOCGKK_01653 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
LOOOCGKK_01654 2.8e-219 brpA K Transcriptional
LOOOCGKK_01655 1.5e-80 rimP S Required for maturation of 30S ribosomal subunits
LOOOCGKK_01656 3.1e-212 nusA K Participates in both transcription termination and antitermination
LOOOCGKK_01657 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
LOOOCGKK_01658 1.4e-41 ylxQ J ribosomal protein
LOOOCGKK_01659 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LOOOCGKK_01660 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LOOOCGKK_01661 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
LOOOCGKK_01662 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
LOOOCGKK_01664 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
LOOOCGKK_01665 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
LOOOCGKK_01666 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LOOOCGKK_01667 1.3e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
LOOOCGKK_01668 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
LOOOCGKK_01669 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
LOOOCGKK_01670 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LOOOCGKK_01672 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LOOOCGKK_01673 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LOOOCGKK_01674 1.2e-74 ylbF S Belongs to the UPF0342 family
LOOOCGKK_01675 7.1e-46 ylbG S UPF0298 protein
LOOOCGKK_01676 1.8e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
LOOOCGKK_01677 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
LOOOCGKK_01678 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
LOOOCGKK_01679 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
LOOOCGKK_01680 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
LOOOCGKK_01681 6.8e-69 acuB S IMP dehydrogenase activity
LOOOCGKK_01682 8.9e-41 acuB S IMP dehydrogenase activity
LOOOCGKK_01683 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LOOOCGKK_01684 1.1e-110 yvyE 3.4.13.9 S YigZ family
LOOOCGKK_01685 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LOOOCGKK_01686 1.7e-122 comFC S Competence protein
LOOOCGKK_01687 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LOOOCGKK_01694 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
LOOOCGKK_01695 6.4e-108 S Domain of unknown function (DUF1803)
LOOOCGKK_01696 7.8e-102 ygaC J Belongs to the UPF0374 family
LOOOCGKK_01697 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
LOOOCGKK_01698 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOOOCGKK_01699 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
LOOOCGKK_01700 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
LOOOCGKK_01701 1.9e-115 S Haloacid dehalogenase-like hydrolase
LOOOCGKK_01702 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
LOOOCGKK_01703 4e-72 marR K Transcriptional regulator, MarR family
LOOOCGKK_01704 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LOOOCGKK_01705 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOOOCGKK_01706 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
LOOOCGKK_01707 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LOOOCGKK_01708 1.6e-126 IQ reductase
LOOOCGKK_01709 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LOOOCGKK_01710 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LOOOCGKK_01711 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LOOOCGKK_01712 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LOOOCGKK_01713 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LOOOCGKK_01714 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LOOOCGKK_01715 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LOOOCGKK_01716 1.3e-125 tnp L Transposase
LOOOCGKK_01717 3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
LOOOCGKK_01718 3.7e-175 gadC E Psort location CytoplasmicMembrane, score 10.00
LOOOCGKK_01719 4.7e-27 L Transposase and inactivated derivatives, TnpA family
LOOOCGKK_01720 3.4e-126 tnp L Transposase
LOOOCGKK_01722 6.8e-276 S Protein of unknown function (DUF3114)
LOOOCGKK_01723 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
LOOOCGKK_01724 7.7e-198 V (ABC) transporter
LOOOCGKK_01725 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
LOOOCGKK_01726 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
LOOOCGKK_01727 1.1e-113 K sequence-specific DNA binding
LOOOCGKK_01728 8.4e-155 L COG2801 Transposase and inactivated derivatives
LOOOCGKK_01729 6.6e-38 L transposase activity
LOOOCGKK_01730 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
LOOOCGKK_01731 1.8e-84 L Transposase
LOOOCGKK_01732 5.5e-122 fruR K transcriptional
LOOOCGKK_01733 6.5e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LOOOCGKK_01734 0.0 fruA 2.7.1.202 G phosphotransferase system
LOOOCGKK_01735 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LOOOCGKK_01736 1e-167 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LOOOCGKK_01738 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
LOOOCGKK_01739 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LOOOCGKK_01740 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
LOOOCGKK_01741 8e-257 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
LOOOCGKK_01742 4.9e-39 2.3.1.128 K acetyltransferase
LOOOCGKK_01743 6.4e-29 2.3.1.128 K acetyltransferase
LOOOCGKK_01744 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LOOOCGKK_01745 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LOOOCGKK_01746 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LOOOCGKK_01747 2.6e-64 WQ51_03320 S cog cog4835
LOOOCGKK_01748 9.8e-91 XK27_08360 S EDD domain protein, DegV family
LOOOCGKK_01749 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LOOOCGKK_01750 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LOOOCGKK_01751 0.0 yfmR S abc transporter atp-binding protein
LOOOCGKK_01752 7.2e-25 U response to pH
LOOOCGKK_01753 6.5e-77 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
LOOOCGKK_01754 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
LOOOCGKK_01755 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
LOOOCGKK_01756 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LOOOCGKK_01757 1.9e-77 K DNA-binding transcription factor activity
LOOOCGKK_01758 0.0 lmrA1 V abc transporter atp-binding protein
LOOOCGKK_01759 0.0 lmrA2 V abc transporter atp-binding protein
LOOOCGKK_01760 9.3e-45 K Acetyltransferase (GNAT) family
LOOOCGKK_01761 2.3e-122 sptS 2.7.13.3 T Histidine kinase
LOOOCGKK_01762 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LOOOCGKK_01763 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LOOOCGKK_01764 2.6e-160 cvfB S Protein conserved in bacteria
LOOOCGKK_01765 7.4e-35 yozE S Belongs to the UPF0346 family
LOOOCGKK_01766 1.5e-123 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
LOOOCGKK_01767 2.3e-61 rlpA M LysM domain protein
LOOOCGKK_01768 8e-191 phoH T phosphate starvation-inducible protein PhoH
LOOOCGKK_01772 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOOOCGKK_01773 1.8e-164 K transcriptional regulator (lysR family)
LOOOCGKK_01774 1.4e-186 coiA 3.6.4.12 S Competence protein
LOOOCGKK_01775 0.0 pepF E oligoendopeptidase F
LOOOCGKK_01776 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
LOOOCGKK_01777 1.7e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
LOOOCGKK_01778 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LOOOCGKK_01779 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LOOOCGKK_01780 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LOOOCGKK_01781 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
LOOOCGKK_01782 1.5e-23 3.4.17.14, 3.5.1.28 NU amidase activity
LOOOCGKK_01783 6.4e-52 3.4.17.14, 3.5.1.28 NU amidase activity
LOOOCGKK_01784 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LOOOCGKK_01785 3.1e-63 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
LOOOCGKK_01786 1.5e-146 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
LOOOCGKK_01787 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LOOOCGKK_01788 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LOOOCGKK_01789 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LOOOCGKK_01790 2.4e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LOOOCGKK_01791 2.2e-130 yxkH G deacetylase
LOOOCGKK_01792 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LOOOCGKK_01793 6.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LOOOCGKK_01794 1.4e-151 rarD S Transporter
LOOOCGKK_01795 2.9e-15 T peptidase
LOOOCGKK_01796 8.9e-14 coiA 3.6.4.12 S Competence protein
LOOOCGKK_01797 8e-51 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LOOOCGKK_01798 5.9e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LOOOCGKK_01799 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LOOOCGKK_01800 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LOOOCGKK_01801 2.4e-114 atpB C it plays a direct role in the translocation of protons across the membrane
LOOOCGKK_01802 3.3e-78 atpF C ATP synthase F(0) sector subunit b
LOOOCGKK_01803 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LOOOCGKK_01804 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LOOOCGKK_01805 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LOOOCGKK_01806 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LOOOCGKK_01807 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LOOOCGKK_01808 2.8e-230 ftsW D Belongs to the SEDS family
LOOOCGKK_01809 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LOOOCGKK_01810 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LOOOCGKK_01811 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LOOOCGKK_01812 6.4e-162 holB 2.7.7.7 L dna polymerase iii
LOOOCGKK_01813 1.2e-135 yaaT S stage 0 sporulation protein
LOOOCGKK_01814 9.5e-55 yabA L Involved in initiation control of chromosome replication
LOOOCGKK_01815 4.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LOOOCGKK_01816 2.9e-232 amt P Ammonium Transporter
LOOOCGKK_01817 6.6e-54 glnB K Belongs to the P(II) protein family
LOOOCGKK_01818 3.2e-105 mur1 NU mannosyl-glycoprotein
LOOOCGKK_01819 2.2e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
LOOOCGKK_01820 4.4e-114 nptA P COG1283 Na phosphate symporter
LOOOCGKK_01821 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LOOOCGKK_01822 7.4e-55
LOOOCGKK_01823 4.4e-26
LOOOCGKK_01824 1.2e-61
LOOOCGKK_01825 1.7e-32 S membrane
LOOOCGKK_01826 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LOOOCGKK_01827 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LOOOCGKK_01828 4.5e-39 ynzC S UPF0291 protein
LOOOCGKK_01829 1.8e-254 cycA E permease
LOOOCGKK_01830 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
LOOOCGKK_01831 4.8e-24 pts33BCA G pts system
LOOOCGKK_01832 1.3e-70 pts33BCA G pts system
LOOOCGKK_01833 9.4e-119 pts33BCA G pts system
LOOOCGKK_01834 1.4e-75 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
LOOOCGKK_01835 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LOOOCGKK_01840 1.4e-167 fhuR K transcriptional regulator (lysR family)
LOOOCGKK_01841 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LOOOCGKK_01842 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LOOOCGKK_01843 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LOOOCGKK_01844 3.7e-227 pyrP F uracil Permease
LOOOCGKK_01845 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LOOOCGKK_01846 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
LOOOCGKK_01847 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
LOOOCGKK_01848 1.4e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
LOOOCGKK_01849 1.7e-29 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LOOOCGKK_01850 3.6e-35 V efflux transmembrane transporter activity
LOOOCGKK_01851 3.1e-31 V efflux transmembrane transporter activity
LOOOCGKK_01852 8.2e-28 ytrF V efflux transmembrane transporter activity
LOOOCGKK_01853 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LOOOCGKK_01854 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LOOOCGKK_01855 9.1e-110 L Transposase
LOOOCGKK_01856 1.2e-109 L Transposase
LOOOCGKK_01857 1.6e-18 L Integrase core domain
LOOOCGKK_01858 2e-162 hrtB V MacB-like periplasmic core domain
LOOOCGKK_01861 2.2e-27 J glyoxalase III activity
LOOOCGKK_01862 4.6e-21 L Transposase
LOOOCGKK_01863 1.2e-15
LOOOCGKK_01865 2.5e-153 mdlB V abc transporter atp-binding protein
LOOOCGKK_01866 1.7e-154 mdlB V abc transporter atp-binding protein
LOOOCGKK_01867 0.0 lmrA V abc transporter atp-binding protein
LOOOCGKK_01868 1.3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LOOOCGKK_01869 2.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LOOOCGKK_01870 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
LOOOCGKK_01871 2.5e-132 rr02 KT response regulator
LOOOCGKK_01872 5.7e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LOOOCGKK_01873 2.8e-168 V ABC transporter
LOOOCGKK_01874 5.4e-122 sagI S ABC-2 type transporter
LOOOCGKK_01875 2.4e-197 yceA S Belongs to the UPF0176 family
LOOOCGKK_01876 8e-28 XK27_00085 K Transcriptional
LOOOCGKK_01877 6.9e-19
LOOOCGKK_01878 6.5e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
LOOOCGKK_01879 9.6e-113 S VIT family
LOOOCGKK_01880 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LOOOCGKK_01881 7e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LOOOCGKK_01882 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
LOOOCGKK_01883 1e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
LOOOCGKK_01884 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LOOOCGKK_01885 8.8e-104 GBS0088 J protein conserved in bacteria
LOOOCGKK_01886 7.9e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
LOOOCGKK_01887 1.6e-171 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LOOOCGKK_01888 2.3e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
LOOOCGKK_01889 2.6e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LOOOCGKK_01890 6.2e-252 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LOOOCGKK_01891 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
LOOOCGKK_01892 2.5e-21
LOOOCGKK_01893 1.7e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LOOOCGKK_01895 3e-29 U protein secretion
LOOOCGKK_01896 4.2e-68 U protein secretion
LOOOCGKK_01897 1.7e-190 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
LOOOCGKK_01898 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
LOOOCGKK_01899 4.9e-21 XK27_13030
LOOOCGKK_01900 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LOOOCGKK_01901 8.9e-57 S hydrolase activity, acting on ester bonds
LOOOCGKK_01902 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LOOOCGKK_01903 6.8e-164 S Protein of unknown function (DUF3114)
LOOOCGKK_01904 1.2e-22 S Protein of unknown function (DUF3114)
LOOOCGKK_01905 1.5e-118 yqfA K protein, Hemolysin III
LOOOCGKK_01906 1e-25 K hmm pf08876
LOOOCGKK_01907 2.2e-232 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LOOOCGKK_01908 1.7e-218 mvaS 2.3.3.10 I synthase
LOOOCGKK_01909 2.9e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LOOOCGKK_01910 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LOOOCGKK_01911 9.7e-22
LOOOCGKK_01912 2.2e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LOOOCGKK_01913 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
LOOOCGKK_01914 6.4e-249 mmuP E amino acid
LOOOCGKK_01915 3.4e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
LOOOCGKK_01916 1.4e-29 S Domain of unknown function (DUF1912)
LOOOCGKK_01917 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
LOOOCGKK_01918 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LOOOCGKK_01919 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LOOOCGKK_01920 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LOOOCGKK_01921 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
LOOOCGKK_01922 4.8e-16 S Protein of unknown function (DUF2969)
LOOOCGKK_01925 4.2e-204 rpsA 1.17.7.4 J ribosomal protein S1
LOOOCGKK_01928 5.1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
LOOOCGKK_01929 3.9e-31 S Domain of Unknown Function with PDB structure (DUF3862)
LOOOCGKK_01930 3.7e-70 M Pfam SNARE associated Golgi protein
LOOOCGKK_01931 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
LOOOCGKK_01932 1.6e-08 S oxidoreductase
LOOOCGKK_01933 9.3e-59 S oxidoreductase
LOOOCGKK_01934 9.7e-66 S oxidoreductase
LOOOCGKK_01935 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
LOOOCGKK_01936 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LOOOCGKK_01937 0.0 clpE O Belongs to the ClpA ClpB family
LOOOCGKK_01938 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LOOOCGKK_01939 1.3e-34 ykuJ S protein conserved in bacteria
LOOOCGKK_01940 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
LOOOCGKK_01941 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
LOOOCGKK_01942 3.1e-78 feoA P FeoA domain protein
LOOOCGKK_01943 1e-309 feoB P transporter of a GTP-driven Fe(2 ) uptake system
LOOOCGKK_01944 2.1e-55 feoB P transporter of a GTP-driven Fe(2 ) uptake system
LOOOCGKK_01945 1.5e-07
LOOOCGKK_01946 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LOOOCGKK_01947 2.2e-45 K sequence-specific DNA binding
LOOOCGKK_01948 1.5e-35 yugF I carboxylic ester hydrolase activity
LOOOCGKK_01949 7.5e-23 I Alpha/beta hydrolase family
LOOOCGKK_01950 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LOOOCGKK_01951 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LOOOCGKK_01952 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
LOOOCGKK_01953 2.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LOOOCGKK_01954 4.9e-63 licT K transcriptional antiterminator
LOOOCGKK_01955 1.7e-51 licT K transcriptional antiterminator
LOOOCGKK_01956 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LOOOCGKK_01957 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LOOOCGKK_01958 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LOOOCGKK_01959 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LOOOCGKK_01960 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LOOOCGKK_01961 2.5e-220 mdtG EGP Major facilitator Superfamily
LOOOCGKK_01962 2e-33 secG U Preprotein translocase subunit SecG
LOOOCGKK_01963 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LOOOCGKK_01964 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LOOOCGKK_01965 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LOOOCGKK_01966 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
LOOOCGKK_01967 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
LOOOCGKK_01968 4.4e-183 ccpA K Catabolite control protein A
LOOOCGKK_01969 2.8e-28 yyaQ S YjbR
LOOOCGKK_01970 6.6e-101 yyaQ V Protein conserved in bacteria
LOOOCGKK_01971 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LOOOCGKK_01972 5.1e-78 yueI S Protein of unknown function (DUF1694)
LOOOCGKK_01973 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)