ORF_ID e_value Gene_name EC_number CAZy COGs Description
KPNFEKOF_00008 5.3e-11
KPNFEKOF_00014 5.5e-139 mreC M Involved in formation and maintenance of cell shape
KPNFEKOF_00015 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KPNFEKOF_00016 3.3e-96 usp 3.5.1.28 CBM50 S CHAP domain
KPNFEKOF_00017 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPNFEKOF_00018 1.1e-217 araT 2.6.1.1 E Aminotransferase
KPNFEKOF_00019 7e-144 recO L Involved in DNA repair and RecF pathway recombination
KPNFEKOF_00020 1.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KPNFEKOF_00021 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPNFEKOF_00022 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KPNFEKOF_00023 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPNFEKOF_00024 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KPNFEKOF_00025 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KPNFEKOF_00026 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KPNFEKOF_00027 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KPNFEKOF_00028 1e-90 L transposase activity
KPNFEKOF_00029 3.5e-50 L transposition
KPNFEKOF_00030 2e-32 L Integrase core domain protein
KPNFEKOF_00031 1.2e-160 S CHAP domain
KPNFEKOF_00032 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
KPNFEKOF_00033 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KPNFEKOF_00034 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KPNFEKOF_00035 2.7e-140 1.1.1.169 H Ketopantoate reductase
KPNFEKOF_00036 9.5e-135 J Domain of unknown function (DUF4041)
KPNFEKOF_00038 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KPNFEKOF_00039 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KPNFEKOF_00040 8.2e-70 argR K Regulates arginine biosynthesis genes
KPNFEKOF_00041 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KPNFEKOF_00042 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KPNFEKOF_00043 7e-34 S Protein of unknown function (DUF3021)
KPNFEKOF_00044 1.2e-61 KT phosphorelay signal transduction system
KPNFEKOF_00046 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KPNFEKOF_00048 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KPNFEKOF_00049 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KPNFEKOF_00050 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
KPNFEKOF_00051 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KPNFEKOF_00052 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KPNFEKOF_00057 4e-167 fhuR K transcriptional regulator (lysR family)
KPNFEKOF_00058 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KPNFEKOF_00059 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KPNFEKOF_00060 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPNFEKOF_00061 4.9e-227 pyrP F uracil Permease
KPNFEKOF_00062 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KPNFEKOF_00063 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KPNFEKOF_00064 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KPNFEKOF_00065 1.9e-125 2.1.1.223 S Putative SAM-dependent methyltransferase
KPNFEKOF_00066 4e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KPNFEKOF_00067 1.2e-50 V efflux transmembrane transporter activity
KPNFEKOF_00068 3.6e-32 V efflux transmembrane transporter activity
KPNFEKOF_00069 7e-27 ytrF V efflux transmembrane transporter activity
KPNFEKOF_00070 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KPNFEKOF_00071 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KPNFEKOF_00072 7.5e-22
KPNFEKOF_00073 2e-133 repA S Replication initiator protein A
KPNFEKOF_00074 9.9e-08
KPNFEKOF_00075 3.6e-252 hpaIIM 2.1.1.37 H cytosine-specific methyltransferase
KPNFEKOF_00076 6.5e-75 XK27_00590
KPNFEKOF_00077 4.2e-65 XK27_00585 P arsenate reductase (glutaredoxin) activity
KPNFEKOF_00078 2.9e-37 XK27_00580
KPNFEKOF_00079 3e-83 ypbD S CAAX protease self-immunity
KPNFEKOF_00080 2.2e-79 XK27_00570
KPNFEKOF_00081 0.0 traG U Type IV secretory system Conjugative DNA transfer
KPNFEKOF_00082 9.2e-34 XK27_00560
KPNFEKOF_00083 9.7e-139
KPNFEKOF_00084 5.2e-62 XK27_00550 S PrgI family protein
KPNFEKOF_00085 0.0 U 'COG3451 Type IV secretory pathway, VirB4 components'
KPNFEKOF_00086 0.0 XK27_00530 M CHAP domain protein
KPNFEKOF_00087 6.2e-108 abiGI K Transcriptional regulator, AbiEi antitoxin
KPNFEKOF_00088 1.7e-148 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
KPNFEKOF_00089 2.9e-249
KPNFEKOF_00090 0.0 XK27_00515 D Glucan-binding protein C
KPNFEKOF_00091 5.4e-13 XK27_00510
KPNFEKOF_00092 2.1e-86 XK27_00505
KPNFEKOF_00093 0.0 XK27_00500 L SNF2 family N-terminal domain
KPNFEKOF_00094 2.2e-45
KPNFEKOF_00095 2.4e-36
KPNFEKOF_00096 4.3e-93 XK27_10865
KPNFEKOF_00097 3.8e-188 L Toprim-like
KPNFEKOF_00098 4.6e-19 XK27_10875
KPNFEKOF_00099 5e-58 XK27_10880
KPNFEKOF_00100 6.2e-37
KPNFEKOF_00101 3.2e-83 nprA K Cro/C1-type HTH DNA-binding domain
KPNFEKOF_00102 1.4e-128 2.7.1.176 O Zeta toxin
KPNFEKOF_00103 1.5e-194
KPNFEKOF_00104 3.8e-109
KPNFEKOF_00105 0.0 L ATPase involved in DNA repair
KPNFEKOF_00108 3e-92 S MucBP domain
KPNFEKOF_00109 5.9e-51 M YSIRK type signal peptide
KPNFEKOF_00110 0.0 M the current gene model (or a revised gene model) may contain a
KPNFEKOF_00112 0.0 mdlB V abc transporter atp-binding protein
KPNFEKOF_00113 0.0 lmrA V abc transporter atp-binding protein
KPNFEKOF_00114 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KPNFEKOF_00115 5.8e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KPNFEKOF_00116 6.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KPNFEKOF_00117 2.3e-113 rr02 KT response regulator
KPNFEKOF_00118 7e-203 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KPNFEKOF_00119 4.8e-168 V ABC transporter
KPNFEKOF_00120 3.5e-121 sagI S ABC-2 type transporter
KPNFEKOF_00121 6.9e-197 yceA S Belongs to the UPF0176 family
KPNFEKOF_00122 1.2e-26 XK27_00085 K Transcriptional
KPNFEKOF_00123 3.1e-20
KPNFEKOF_00124 8.2e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
KPNFEKOF_00125 9.6e-113 S VIT family
KPNFEKOF_00126 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KPNFEKOF_00127 3.9e-148 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KPNFEKOF_00128 2.1e-61 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KPNFEKOF_00129 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
KPNFEKOF_00130 1e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KPNFEKOF_00131 8.8e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPNFEKOF_00132 2.4e-07 ytjP 3.5.1.18 E Dipeptidase
KPNFEKOF_00133 3.2e-97 ET Bacterial extracellular solute-binding proteins, family 3
KPNFEKOF_00134 1.9e-59 K Acetyltransferase (GNAT) domain
KPNFEKOF_00136 7.3e-151 1.8.5.7 O Glutathione S-transferase
KPNFEKOF_00137 1.2e-170 1.8.5.7 O Glutathione S-transferase, C-terminal domain
KPNFEKOF_00138 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KPNFEKOF_00139 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KPNFEKOF_00140 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
KPNFEKOF_00141 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KPNFEKOF_00142 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KPNFEKOF_00143 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KPNFEKOF_00144 2.5e-21
KPNFEKOF_00145 8.5e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPNFEKOF_00147 6.1e-50 U protein secretion
KPNFEKOF_00148 1.6e-10 U protein secretion
KPNFEKOF_00149 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KPNFEKOF_00150 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KPNFEKOF_00151 4.9e-21 XK27_13030
KPNFEKOF_00152 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPNFEKOF_00153 8.9e-57 S hydrolase activity, acting on ester bonds
KPNFEKOF_00154 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KPNFEKOF_00155 2.8e-165 S Protein of unknown function (DUF3114)
KPNFEKOF_00156 1.2e-22 S Protein of unknown function (DUF3114)
KPNFEKOF_00157 1.5e-118 yqfA K protein, Hemolysin III
KPNFEKOF_00158 1.5e-24 K hmm pf08876
KPNFEKOF_00159 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KPNFEKOF_00160 1.9e-217 mvaS 2.3.3.10 I synthase
KPNFEKOF_00161 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KPNFEKOF_00162 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPNFEKOF_00163 9.7e-22
KPNFEKOF_00164 3.7e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KPNFEKOF_00165 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KPNFEKOF_00166 9.2e-248 mmuP E amino acid
KPNFEKOF_00167 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KPNFEKOF_00168 1.4e-29 S Domain of unknown function (DUF1912)
KPNFEKOF_00169 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
KPNFEKOF_00170 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KPNFEKOF_00171 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KPNFEKOF_00172 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KPNFEKOF_00173 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
KPNFEKOF_00174 4.8e-16 S Protein of unknown function (DUF2969)
KPNFEKOF_00177 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
KPNFEKOF_00180 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
KPNFEKOF_00181 6.1e-70 M Pfam SNARE associated Golgi protein
KPNFEKOF_00182 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
KPNFEKOF_00183 1.6e-08 S oxidoreductase
KPNFEKOF_00184 9.3e-59 S oxidoreductase
KPNFEKOF_00185 1.5e-66 S oxidoreductase
KPNFEKOF_00186 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
KPNFEKOF_00187 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KPNFEKOF_00188 0.0 clpE O Belongs to the ClpA ClpB family
KPNFEKOF_00189 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KPNFEKOF_00190 1.3e-34 ykuJ S protein conserved in bacteria
KPNFEKOF_00191 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KPNFEKOF_00192 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
KPNFEKOF_00193 2.4e-78 feoA P FeoA domain protein
KPNFEKOF_00194 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KPNFEKOF_00195 1.5e-07
KPNFEKOF_00196 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KPNFEKOF_00197 2.2e-45 K sequence-specific DNA binding
KPNFEKOF_00198 1.5e-35 yugF I carboxylic ester hydrolase activity
KPNFEKOF_00199 7.5e-23 I Alpha/beta hydrolase family
KPNFEKOF_00200 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KPNFEKOF_00201 7e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KPNFEKOF_00202 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KPNFEKOF_00203 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KPNFEKOF_00204 1.7e-63 licT K transcriptional antiterminator
KPNFEKOF_00205 6.8e-53 licT K transcriptional antiterminator
KPNFEKOF_00206 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KPNFEKOF_00207 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KPNFEKOF_00208 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KPNFEKOF_00209 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KPNFEKOF_00210 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPNFEKOF_00211 6e-133 mdtG EGP Major facilitator Superfamily
KPNFEKOF_00212 9.5e-74 mdtG EGP Major facilitator Superfamily
KPNFEKOF_00213 2e-33 secG U Preprotein translocase subunit SecG
KPNFEKOF_00214 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KPNFEKOF_00215 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KPNFEKOF_00216 4.1e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KPNFEKOF_00217 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KPNFEKOF_00218 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KPNFEKOF_00219 4.4e-183 ccpA K Catabolite control protein A
KPNFEKOF_00220 2.8e-28 yyaQ S YjbR
KPNFEKOF_00221 2.5e-89 yyaQ V Protein conserved in bacteria
KPNFEKOF_00222 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KPNFEKOF_00223 1e-78 yueI S Protein of unknown function (DUF1694)
KPNFEKOF_00224 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KPNFEKOF_00226 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KPNFEKOF_00227 2e-219 ywbD 2.1.1.191 J Methyltransferase
KPNFEKOF_00228 1.1e-121 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KPNFEKOF_00229 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPNFEKOF_00230 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KPNFEKOF_00231 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KPNFEKOF_00232 8.3e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KPNFEKOF_00233 3.2e-53 yheA S Belongs to the UPF0342 family
KPNFEKOF_00234 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KPNFEKOF_00235 5.8e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KPNFEKOF_00236 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KPNFEKOF_00237 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
KPNFEKOF_00238 2.6e-253 msrR K Transcriptional regulator
KPNFEKOF_00239 1.2e-147 ydiA P C4-dicarboxylate transporter malic acid transport protein
KPNFEKOF_00240 7e-203 I acyl-CoA dehydrogenase
KPNFEKOF_00241 4.5e-97 mip S hydroperoxide reductase activity
KPNFEKOF_00242 5.3e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPNFEKOF_00243 4.7e-106
KPNFEKOF_00244 1.2e-27 estA E GDSL-like Lipase/Acylhydrolase
KPNFEKOF_00245 1.4e-94
KPNFEKOF_00246 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KPNFEKOF_00247 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KPNFEKOF_00248 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KPNFEKOF_00249 9e-195 S CRISPR-associated protein Csn2 subfamily St
KPNFEKOF_00250 1.3e-148 ycgQ S TIGR03943 family
KPNFEKOF_00251 3.5e-155 XK27_03015 S permease
KPNFEKOF_00253 0.0 yhgF K Transcriptional accessory protein
KPNFEKOF_00254 9.9e-42 pspC KT PspC domain
KPNFEKOF_00255 9.8e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KPNFEKOF_00256 5.3e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KPNFEKOF_00258 5.5e-69 ytxH S General stress protein
KPNFEKOF_00260 2e-177 yegQ O Peptidase U32
KPNFEKOF_00261 3.4e-252 yegQ O Peptidase U32
KPNFEKOF_00262 8.1e-46 S CHY zinc finger
KPNFEKOF_00263 7.1e-87 bioY S biotin synthase
KPNFEKOF_00265 1.1e-33 XK27_12190 S protein conserved in bacteria
KPNFEKOF_00266 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
KPNFEKOF_00267 4e-10
KPNFEKOF_00268 1.7e-208 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KPNFEKOF_00269 4.1e-225 mutH L DNA mismatch repair enzyme MutH
KPNFEKOF_00270 5.1e-206 S SIR2-like domain
KPNFEKOF_00271 1.4e-234 S Domain of unknown function DUF87
KPNFEKOF_00274 2.2e-12
KPNFEKOF_00275 8.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KPNFEKOF_00276 1.6e-158 M LysM domain
KPNFEKOF_00277 7.6e-16
KPNFEKOF_00278 6.4e-173 S hydrolase
KPNFEKOF_00279 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
KPNFEKOF_00280 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KPNFEKOF_00281 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
KPNFEKOF_00282 2.7e-27 P Hemerythrin HHE cation binding domain protein
KPNFEKOF_00283 7.4e-112 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPNFEKOF_00284 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
KPNFEKOF_00285 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
KPNFEKOF_00286 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
KPNFEKOF_00287 8.1e-288 hsdM 2.1.1.72 V N-6 DNA Methylase
KPNFEKOF_00288 4.4e-137 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KPNFEKOF_00289 1.5e-11
KPNFEKOF_00290 9.8e-70
KPNFEKOF_00291 3.2e-173 spd F DNA RNA non-specific endonuclease
KPNFEKOF_00292 2.2e-91 lemA S LemA family
KPNFEKOF_00293 5.3e-135 htpX O Belongs to the peptidase M48B family
KPNFEKOF_00294 1.8e-73 S Psort location CytoplasmicMembrane, score
KPNFEKOF_00295 6.2e-56 S Domain of unknown function (DUF4430)
KPNFEKOF_00296 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KPNFEKOF_00297 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
KPNFEKOF_00298 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KPNFEKOF_00299 1.4e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KPNFEKOF_00300 7.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KPNFEKOF_00301 7.1e-92 dps P Belongs to the Dps family
KPNFEKOF_00302 3.4e-79 perR P Belongs to the Fur family
KPNFEKOF_00303 1.9e-27 yqgQ S protein conserved in bacteria
KPNFEKOF_00304 2.9e-179 glk 2.7.1.2 G Glucokinase
KPNFEKOF_00305 0.0 typA T GTP-binding protein TypA
KPNFEKOF_00307 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KPNFEKOF_00308 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KPNFEKOF_00309 1.8e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KPNFEKOF_00310 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KPNFEKOF_00311 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KPNFEKOF_00312 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KPNFEKOF_00313 6.8e-96 sepF D cell septum assembly
KPNFEKOF_00314 2.6e-34 yggT D integral membrane protein
KPNFEKOF_00315 4.2e-144 ylmH T S4 RNA-binding domain
KPNFEKOF_00316 1.8e-135 divIVA D Cell division protein DivIVA
KPNFEKOF_00317 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KPNFEKOF_00318 5.5e-30
KPNFEKOF_00319 8.4e-10
KPNFEKOF_00320 2.4e-15 mntH P Mn2 and Fe2 transporters of the NRAMP family
KPNFEKOF_00321 4.3e-175 mntH P Mn2 and Fe2 transporters of the NRAMP family
KPNFEKOF_00322 2e-45 rpmE2 J 50S ribosomal protein L31
KPNFEKOF_00323 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KPNFEKOF_00324 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KPNFEKOF_00325 8.9e-155 gst O Glutathione S-transferase
KPNFEKOF_00326 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KPNFEKOF_00327 6.6e-110 tdk 2.7.1.21 F thymidine kinase
KPNFEKOF_00328 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KPNFEKOF_00329 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KPNFEKOF_00330 2.8e-108 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KPNFEKOF_00331 4e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KPNFEKOF_00332 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
KPNFEKOF_00333 2.7e-106 pvaA M lytic transglycosylase activity
KPNFEKOF_00334 0.0 yfiB1 V abc transporter atp-binding protein
KPNFEKOF_00335 0.0 XK27_10035 V abc transporter atp-binding protein
KPNFEKOF_00336 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
KPNFEKOF_00337 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPNFEKOF_00338 3.9e-237 dltB M Membrane protein involved in D-alanine export
KPNFEKOF_00339 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPNFEKOF_00340 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KPNFEKOF_00341 3.9e-51 L transposition
KPNFEKOF_00342 3.2e-10 L transposase activity
KPNFEKOF_00343 2.5e-40 L Transposase
KPNFEKOF_00344 0.0 3.6.3.8 P cation transport ATPase
KPNFEKOF_00345 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KPNFEKOF_00347 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KPNFEKOF_00348 7.3e-166 metF 1.5.1.20 E reductase
KPNFEKOF_00349 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KPNFEKOF_00350 9.2e-93 panT S ECF transporter, substrate-specific component
KPNFEKOF_00351 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KPNFEKOF_00352 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KPNFEKOF_00353 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KPNFEKOF_00354 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPNFEKOF_00355 2.8e-40 T PhoQ Sensor
KPNFEKOF_00356 1.7e-43 T PhoQ Sensor
KPNFEKOF_00357 1.4e-127 T PhoQ Sensor
KPNFEKOF_00358 2.1e-30 rpsT J rRNA binding
KPNFEKOF_00359 2.7e-171 coaA 2.7.1.33 F Pantothenic acid kinase
KPNFEKOF_00360 2.4e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
KPNFEKOF_00361 2.3e-26 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KPNFEKOF_00362 5.1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
KPNFEKOF_00363 1.2e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KPNFEKOF_00364 3.2e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KPNFEKOF_00365 2e-14 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KPNFEKOF_00366 1.4e-48 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KPNFEKOF_00367 8e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KPNFEKOF_00368 1.1e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KPNFEKOF_00369 1e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
KPNFEKOF_00370 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KPNFEKOF_00371 1.2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KPNFEKOF_00372 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KPNFEKOF_00373 3.1e-81 ypmB S Protein conserved in bacteria
KPNFEKOF_00374 4.7e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KPNFEKOF_00375 4.9e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KPNFEKOF_00376 3.7e-19
KPNFEKOF_00377 2.1e-200 pmrB EGP Major facilitator Superfamily
KPNFEKOF_00378 3.3e-62 tdcF 3.5.99.10 J endoribonuclease L-PSP
KPNFEKOF_00379 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KPNFEKOF_00380 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KPNFEKOF_00381 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KPNFEKOF_00382 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KPNFEKOF_00383 4.5e-20 D nuclear chromosome segregation
KPNFEKOF_00384 5.3e-136 yejC S cyclic nucleotide-binding protein
KPNFEKOF_00385 3.5e-163 rapZ S Displays ATPase and GTPase activities
KPNFEKOF_00386 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KPNFEKOF_00387 8.7e-162 whiA K May be required for sporulation
KPNFEKOF_00388 6.4e-168 pepD E Dipeptidase
KPNFEKOF_00389 5.4e-32 cspD K Cold shock protein domain
KPNFEKOF_00390 8e-42 K Cold-Shock Protein
KPNFEKOF_00391 0.0 copB 3.6.3.4 P P-type ATPase
KPNFEKOF_00392 2.6e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KPNFEKOF_00393 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KPNFEKOF_00394 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KPNFEKOF_00395 1.5e-59 cysE 2.3.1.30 E serine acetyltransferase
KPNFEKOF_00397 1.9e-07
KPNFEKOF_00402 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPNFEKOF_00403 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KPNFEKOF_00404 5.5e-36 XK27_02060 S Transglycosylase associated protein
KPNFEKOF_00405 2.6e-55 badR K DNA-binding transcription factor activity
KPNFEKOF_00406 3.5e-97 S reductase
KPNFEKOF_00407 3.4e-88 L Integrase core domain protein
KPNFEKOF_00408 6.4e-41 L transposition
KPNFEKOF_00409 1.2e-76 yocD 3.4.17.13 V carboxypeptidase activity
KPNFEKOF_00410 7.8e-79 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KPNFEKOF_00412 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KPNFEKOF_00413 3e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KPNFEKOF_00414 1.1e-83 S Putative small multi-drug export protein
KPNFEKOF_00415 6.2e-76 ctsR K Belongs to the CtsR family
KPNFEKOF_00416 0.0 clpC O Belongs to the ClpA ClpB family
KPNFEKOF_00417 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KPNFEKOF_00418 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KPNFEKOF_00419 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KPNFEKOF_00420 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KPNFEKOF_00421 1e-142 S SseB protein N-terminal domain
KPNFEKOF_00422 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
KPNFEKOF_00423 3.9e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPNFEKOF_00424 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KPNFEKOF_00427 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPNFEKOF_00428 3.5e-91 yacP S RNA-binding protein containing a PIN domain
KPNFEKOF_00429 3.4e-155 degV S DegV family
KPNFEKOF_00430 1.8e-31 K helix-turn-helix
KPNFEKOF_00431 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KPNFEKOF_00432 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KPNFEKOF_00433 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KPNFEKOF_00434 4.1e-36 K sequence-specific DNA binding
KPNFEKOF_00436 5.1e-279
KPNFEKOF_00437 3.9e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
KPNFEKOF_00438 4.4e-112 hsdM 2.1.1.72 V type I restriction-modification system
KPNFEKOF_00439 1.1e-156 glcU U Glucose uptake
KPNFEKOF_00440 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
KPNFEKOF_00441 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
KPNFEKOF_00442 1.5e-75 XK27_10720 D peptidase activity
KPNFEKOF_00443 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
KPNFEKOF_00444 1.7e-08
KPNFEKOF_00445 1.2e-172 yeiH S Membrane
KPNFEKOF_00446 1.2e-118 mur1 NU muramidase
KPNFEKOF_00447 1.4e-83 L transposition
KPNFEKOF_00448 2.6e-166 cpsY K Transcriptional regulator
KPNFEKOF_00449 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KPNFEKOF_00450 1.2e-57 phnA P Alkylphosphonate utilization operon protein PhnA
KPNFEKOF_00451 2e-104 artQ P ABC transporter (Permease
KPNFEKOF_00452 4e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
KPNFEKOF_00453 1.6e-157 aatB ET ABC transporter substrate-binding protein
KPNFEKOF_00454 1.4e-72 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPNFEKOF_00455 2.5e-110 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPNFEKOF_00456 1.7e-57 adhP 1.1.1.1 C alcohol dehydrogenase
KPNFEKOF_00457 2.7e-112 adhP 1.1.1.1 C alcohol dehydrogenase
KPNFEKOF_00458 3e-21
KPNFEKOF_00459 0.0 res_1 3.1.21.5 S Type III restriction
KPNFEKOF_00460 0.0 sthIM 2.1.1.72 L DNA methylase
KPNFEKOF_00462 3.4e-90 L Homeodomain-like domain
KPNFEKOF_00463 2.2e-34
KPNFEKOF_00464 9.2e-26 yozV S Protein of unknown function (DUF2628)
KPNFEKOF_00466 1.2e-75 3.1.3.16 S Protein of unknown function (DUF1643)
KPNFEKOF_00468 0.0 L Domain of unknown function (DUF927)
KPNFEKOF_00469 2.2e-22 S Domain of unknown function (DUF3173)
KPNFEKOF_00470 5.3e-207 L Phage integrase SAM-like domain
KPNFEKOF_00471 1.8e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KPNFEKOF_00472 3.5e-126 gntR1 K transcriptional
KPNFEKOF_00473 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KPNFEKOF_00474 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KPNFEKOF_00475 4.1e-87 niaX
KPNFEKOF_00476 1.3e-90 niaR S small molecule binding protein (contains 3H domain)
KPNFEKOF_00477 8.1e-128 K DNA-binding helix-turn-helix protein
KPNFEKOF_00478 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KPNFEKOF_00479 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPNFEKOF_00480 4.1e-167 GK ROK family
KPNFEKOF_00481 8.3e-159 dprA LU DNA protecting protein DprA
KPNFEKOF_00482 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPNFEKOF_00483 6.9e-150 S TraX protein
KPNFEKOF_00484 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPNFEKOF_00485 2.4e-251 T PhoQ Sensor
KPNFEKOF_00486 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KPNFEKOF_00487 5.4e-152 XK27_05470 E Methionine synthase
KPNFEKOF_00488 1.1e-74 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KPNFEKOF_00489 1.8e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPNFEKOF_00490 1.4e-51 IQ Acetoin reductase
KPNFEKOF_00491 3.9e-19 IQ Acetoin reductase
KPNFEKOF_00492 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KPNFEKOF_00493 1.3e-154 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KPNFEKOF_00496 1.3e-212 pqqE C radical SAM domain protein
KPNFEKOF_00497 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
KPNFEKOF_00498 6.6e-61 EGP Major facilitator Superfamily
KPNFEKOF_00499 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KPNFEKOF_00500 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KPNFEKOF_00501 6.4e-104 V ABC transporter (Permease
KPNFEKOF_00502 8.4e-112 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KPNFEKOF_00503 1.6e-10
KPNFEKOF_00504 6.9e-98 K Transcriptional regulator, TetR family
KPNFEKOF_00505 3.1e-159 czcD P cation diffusion facilitator family transporter
KPNFEKOF_00506 1.1e-198 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KPNFEKOF_00507 6.8e-195 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KPNFEKOF_00508 6e-08 S Hydrolases of the alpha beta superfamily
KPNFEKOF_00509 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
KPNFEKOF_00510 3.2e-77 S Alpha/beta hydrolase of unknown function (DUF915)
KPNFEKOF_00513 6e-64 2.4.2.3 F Phosphorylase superfamily
KPNFEKOF_00514 1.2e-70 2.4.2.3 F Phosphorylase superfamily
KPNFEKOF_00515 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KPNFEKOF_00516 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
KPNFEKOF_00517 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
KPNFEKOF_00518 4.7e-56 dinF V Mate efflux family protein
KPNFEKOF_00519 3.9e-15 dinF V Mate efflux family protein
KPNFEKOF_00521 6e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KPNFEKOF_00523 4.6e-60 S TraX protein
KPNFEKOF_00524 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KPNFEKOF_00525 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KPNFEKOF_00526 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KPNFEKOF_00527 1e-179 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KPNFEKOF_00528 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KPNFEKOF_00529 6.8e-133 cas6 S Pfam:DUF2276
KPNFEKOF_00530 0.0 csm1 S CRISPR-associated protein Csm1 family
KPNFEKOF_00531 5.6e-62 csm2 L Pfam:DUF310
KPNFEKOF_00532 1.1e-116 csm3 L RAMP superfamily
KPNFEKOF_00533 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
KPNFEKOF_00534 5.8e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
KPNFEKOF_00535 2.1e-14 csm6 S Psort location Cytoplasmic, score
KPNFEKOF_00536 1.2e-73 csm6 S Psort location Cytoplasmic, score
KPNFEKOF_00537 2e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KPNFEKOF_00538 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KPNFEKOF_00539 1.3e-65 nylA 3.5.1.4 J Belongs to the amidase family
KPNFEKOF_00540 7.9e-266 dtpT E transporter
KPNFEKOF_00541 1.4e-62 yecS P ABC transporter (Permease
KPNFEKOF_00542 2.3e-20 yecS P amino acid transport
KPNFEKOF_00544 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KPNFEKOF_00545 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
KPNFEKOF_00546 1.4e-104 yfiF3 K sequence-specific DNA binding
KPNFEKOF_00547 1.9e-13
KPNFEKOF_00548 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KPNFEKOF_00549 1.8e-240 agcS E (Alanine) symporter
KPNFEKOF_00550 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KPNFEKOF_00551 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
KPNFEKOF_00552 1.8e-59 Q phosphatase activity
KPNFEKOF_00553 9.3e-62 S haloacid dehalogenase-like hydrolase
KPNFEKOF_00554 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KPNFEKOF_00555 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KPNFEKOF_00556 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
KPNFEKOF_00557 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
KPNFEKOF_00558 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KPNFEKOF_00559 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KPNFEKOF_00560 4.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KPNFEKOF_00561 1.9e-43 yktA S Belongs to the UPF0223 family
KPNFEKOF_00562 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KPNFEKOF_00563 1.1e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KPNFEKOF_00564 3.3e-158 pstS P phosphate
KPNFEKOF_00565 8.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
KPNFEKOF_00566 1.2e-155 pstA P phosphate transport system permease
KPNFEKOF_00567 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPNFEKOF_00568 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KPNFEKOF_00569 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
KPNFEKOF_00570 0.0 pepN 3.4.11.2 E aminopeptidase
KPNFEKOF_00571 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KPNFEKOF_00572 2.9e-187 lplA 6.3.1.20 H Lipoate-protein ligase
KPNFEKOF_00573 1.1e-17
KPNFEKOF_00574 3.7e-09
KPNFEKOF_00575 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KPNFEKOF_00576 1.1e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KPNFEKOF_00577 2.3e-23 L Transposase
KPNFEKOF_00578 4.6e-25 tatA U protein secretion
KPNFEKOF_00579 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KPNFEKOF_00580 1.4e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KPNFEKOF_00581 5.6e-233 ycdB P peroxidase
KPNFEKOF_00582 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
KPNFEKOF_00583 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KPNFEKOF_00584 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KPNFEKOF_00585 6.6e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KPNFEKOF_00586 2.5e-50 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KPNFEKOF_00587 1.2e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KPNFEKOF_00588 1.9e-37 3.5.1.28 NU amidase activity
KPNFEKOF_00589 8.5e-266 3.5.1.28 NU amidase activity
KPNFEKOF_00590 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KPNFEKOF_00591 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KPNFEKOF_00592 0.0 lpdA 1.8.1.4 C Dehydrogenase
KPNFEKOF_00593 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KPNFEKOF_00594 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KPNFEKOF_00595 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KPNFEKOF_00596 5e-38 P membrane protein (DUF2207)
KPNFEKOF_00597 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
KPNFEKOF_00598 8.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KPNFEKOF_00599 1.1e-126 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KPNFEKOF_00600 3.3e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPNFEKOF_00601 1.3e-159 rssA S Phospholipase, patatin family
KPNFEKOF_00602 3.9e-78 estA E GDSL-like protein
KPNFEKOF_00603 2.6e-15 estA E Lysophospholipase L1 and related esterases
KPNFEKOF_00604 4.1e-292 S unusual protein kinase
KPNFEKOF_00605 4.9e-39 S granule-associated protein
KPNFEKOF_00606 7.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPNFEKOF_00607 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
KPNFEKOF_00608 7.7e-67 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPNFEKOF_00609 1.5e-198 S hmm pf01594
KPNFEKOF_00610 6.2e-44 G alpha-ribazole phosphatase activity
KPNFEKOF_00611 2.1e-89 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KPNFEKOF_00612 2.2e-94 V VanZ like family
KPNFEKOF_00613 1.3e-50 L Transposase
KPNFEKOF_00614 1e-159 L Transposase
KPNFEKOF_00615 7.1e-128 cps1C S Polysaccharide biosynthesis protein
KPNFEKOF_00616 2.2e-80 cps1C S Polysaccharide biosynthesis protein
KPNFEKOF_00617 2e-95 2.7.8.12 GT2 S Glycosyltransferase like family 2
KPNFEKOF_00618 8.9e-127 tnp L DDE domain
KPNFEKOF_00619 7.4e-137 capM K Cell envelope-related transcriptional attenuator domain
KPNFEKOF_00620 6.2e-152 Dcc 3.1.3.1, 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.4.17.14, 3.6.1.45 G Phosphodiester glycosidase
KPNFEKOF_00621 2e-33 L Transposase DDE domain
KPNFEKOF_00622 1.1e-22 S Glycosyl transferase family 2
KPNFEKOF_00623 3.8e-80 M Glycosyl transferase, family 2
KPNFEKOF_00624 2.4e-31 2.4.1.52 GT4 V Glycosyl transferase, family 2
KPNFEKOF_00625 9.5e-29
KPNFEKOF_00626 2.8e-61 GT2 S Glycosyl transferase family 2
KPNFEKOF_00627 9.6e-38 rfbF GT2 S Glycosyl transferase family 2
KPNFEKOF_00628 3.1e-25 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KPNFEKOF_00629 2.2e-57 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KPNFEKOF_00630 1.6e-100 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KPNFEKOF_00631 3.6e-42 M Psort location Cytoplasmic, score 8.87
KPNFEKOF_00632 7.1e-31 M Psort location Cytoplasmic, score 8.87
KPNFEKOF_00633 4.3e-39 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KPNFEKOF_00634 4.4e-152 M Glycosyl transferases group 1
KPNFEKOF_00635 4.5e-200 glf 5.4.99.9 M UDP-galactopyranose mutase
KPNFEKOF_00636 3.2e-31 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KPNFEKOF_00637 4.8e-48 L Transposase
KPNFEKOF_00638 6.8e-90 L Transposase
KPNFEKOF_00639 8.7e-126 cps1C S Polysaccharide biosynthesis protein
KPNFEKOF_00640 8.4e-80 cps1C S Polysaccharide biosynthesis protein
KPNFEKOF_00641 2.2e-249 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KPNFEKOF_00642 2.2e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
KPNFEKOF_00643 1.4e-106 cps4C M biosynthesis protein
KPNFEKOF_00644 3.9e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KPNFEKOF_00645 5.2e-249 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KPNFEKOF_00646 6.9e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KPNFEKOF_00647 1.4e-49 yfeJ 6.3.5.2 F glutamine amidotransferase
KPNFEKOF_00648 2.5e-43 yfeJ 6.3.5.2 F glutamine amidotransferase
KPNFEKOF_00649 1e-55 clcA_2 P chloride
KPNFEKOF_00650 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KPNFEKOF_00651 5.5e-87 S Protein of unknown function (DUF1697)
KPNFEKOF_00652 6.4e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KPNFEKOF_00653 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KPNFEKOF_00655 5.7e-08 V Glucan-binding protein C
KPNFEKOF_00656 1.1e-31 V Glucan-binding protein C
KPNFEKOF_00657 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
KPNFEKOF_00658 2e-274 pepV 3.5.1.18 E Dipeptidase
KPNFEKOF_00659 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KPNFEKOF_00660 2e-41 XK27_03610 K Gnat family
KPNFEKOF_00661 7.2e-83 L Transposase
KPNFEKOF_00662 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KPNFEKOF_00663 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KPNFEKOF_00664 5.9e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KPNFEKOF_00665 7.3e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KPNFEKOF_00666 7.9e-16 M LysM domain
KPNFEKOF_00667 2.9e-90 ebsA S Family of unknown function (DUF5322)
KPNFEKOF_00668 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KPNFEKOF_00669 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KPNFEKOF_00670 4.9e-224 G COG0457 FOG TPR repeat
KPNFEKOF_00671 1.7e-178 yubA S permease
KPNFEKOF_00672 1.7e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KPNFEKOF_00673 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KPNFEKOF_00674 2.5e-124 ftsE D cell division ATP-binding protein FtsE
KPNFEKOF_00675 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KPNFEKOF_00676 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KPNFEKOF_00677 4.3e-180 yjjH S Calcineurin-like phosphoesterase
KPNFEKOF_00678 2e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KPNFEKOF_00679 0.0 pacL 3.6.3.8 P cation transport ATPase
KPNFEKOF_00680 2.6e-67 ywiB S Domain of unknown function (DUF1934)
KPNFEKOF_00681 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
KPNFEKOF_00682 9.2e-147 yidA S hydrolases of the HAD superfamily
KPNFEKOF_00683 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KPNFEKOF_00684 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KPNFEKOF_00685 4.5e-247 vicK 2.7.13.3 T Histidine kinase
KPNFEKOF_00686 2.9e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPNFEKOF_00687 3.7e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
KPNFEKOF_00688 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KPNFEKOF_00689 5.9e-118 gltJ P ABC transporter (Permease
KPNFEKOF_00690 1.7e-111 tcyB_2 P ABC transporter (permease)
KPNFEKOF_00691 2.4e-124 endA F DNA RNA non-specific endonuclease
KPNFEKOF_00692 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
KPNFEKOF_00693 6.5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPNFEKOF_00695 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KPNFEKOF_00696 6.4e-20 G Domain of unknown function (DUF4832)
KPNFEKOF_00697 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KPNFEKOF_00698 1.6e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KPNFEKOF_00699 1.2e-294 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPNFEKOF_00700 6.1e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KPNFEKOF_00701 1.3e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KPNFEKOF_00702 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
KPNFEKOF_00704 7.7e-35
KPNFEKOF_00707 5.4e-203 S Phage integrase family
KPNFEKOF_00709 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KPNFEKOF_00710 2.1e-219 XK27_05110 P chloride
KPNFEKOF_00711 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KPNFEKOF_00712 1.3e-282 clcA P Chloride transporter, ClC family
KPNFEKOF_00713 2.3e-75 fld C Flavodoxin
KPNFEKOF_00714 1.1e-14 XK27_08880
KPNFEKOF_00715 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
KPNFEKOF_00716 2e-151 estA CE1 S Putative esterase
KPNFEKOF_00717 1.1e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPNFEKOF_00718 4.4e-135 XK27_08845 S abc transporter atp-binding protein
KPNFEKOF_00719 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KPNFEKOF_00720 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
KPNFEKOF_00722 1.7e-11 Q the current gene model (or a revised gene model) may contain a frame shift
KPNFEKOF_00723 1.1e-27 Q the current gene model (or a revised gene model) may contain a frame shift
KPNFEKOF_00724 1.9e-275 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KPNFEKOF_00725 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KPNFEKOF_00726 0.0 dnaE 2.7.7.7 L DNA polymerase
KPNFEKOF_00727 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
KPNFEKOF_00728 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KPNFEKOF_00729 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KPNFEKOF_00730 9.6e-43 ysdA L Membrane
KPNFEKOF_00731 5.6e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KPNFEKOF_00732 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KPNFEKOF_00733 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KPNFEKOF_00734 1.4e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KPNFEKOF_00736 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KPNFEKOF_00737 1.7e-83 ypmS S Protein conserved in bacteria
KPNFEKOF_00738 3.9e-143 ypmR E lipolytic protein G-D-S-L family
KPNFEKOF_00739 1.5e-147 DegV S DegV family
KPNFEKOF_00740 6.4e-304 recN L May be involved in recombinational repair of damaged DNA
KPNFEKOF_00741 1.8e-72 argR K Regulates arginine biosynthesis genes
KPNFEKOF_00742 4.7e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KPNFEKOF_00743 9.6e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KPNFEKOF_00744 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
KPNFEKOF_00745 2.6e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KPNFEKOF_00746 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KPNFEKOF_00747 3.8e-125 dnaD
KPNFEKOF_00748 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KPNFEKOF_00749 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPNFEKOF_00750 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KPNFEKOF_00751 2.4e-136 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KPNFEKOF_00752 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KPNFEKOF_00753 1.2e-117 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KPNFEKOF_00754 1.2e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPNFEKOF_00755 1e-233 rodA D Belongs to the SEDS family
KPNFEKOF_00756 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
KPNFEKOF_00757 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KPNFEKOF_00758 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KPNFEKOF_00759 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KPNFEKOF_00760 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KPNFEKOF_00761 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KPNFEKOF_00762 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KPNFEKOF_00763 1.4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KPNFEKOF_00764 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KPNFEKOF_00765 4.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KPNFEKOF_00767 1.4e-86 L Integrase core domain protein
KPNFEKOF_00768 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KPNFEKOF_00769 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KPNFEKOF_00770 7.9e-39 ptsH G phosphocarrier protein Hpr
KPNFEKOF_00771 3.7e-221 icd 1.1.1.42 C Isocitrate dehydrogenase
KPNFEKOF_00772 1.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
KPNFEKOF_00773 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KPNFEKOF_00774 2.2e-34 nrdH O Glutaredoxin
KPNFEKOF_00775 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPNFEKOF_00776 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPNFEKOF_00778 4.2e-71 L Transposase (IS116 IS110 IS902 family)
KPNFEKOF_00779 3.3e-26 L Transposase (IS116 IS110 IS902 family)
KPNFEKOF_00780 1.2e-164 ypuA S secreted protein
KPNFEKOF_00781 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
KPNFEKOF_00782 5.1e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KPNFEKOF_00783 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPNFEKOF_00784 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KPNFEKOF_00785 3.4e-258 noxE P NADH oxidase
KPNFEKOF_00786 1.9e-294 yfmM S abc transporter atp-binding protein
KPNFEKOF_00787 4.7e-83 XK27_01265 S ECF-type riboflavin transporter, S component
KPNFEKOF_00788 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KPNFEKOF_00789 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KPNFEKOF_00790 2e-86 S ECF-type riboflavin transporter, S component
KPNFEKOF_00792 2.9e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KPNFEKOF_00793 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KPNFEKOF_00796 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPNFEKOF_00797 4.6e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPNFEKOF_00798 1.2e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KPNFEKOF_00799 0.0 smc D Required for chromosome condensation and partitioning
KPNFEKOF_00800 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KPNFEKOF_00801 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KPNFEKOF_00802 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPNFEKOF_00803 2.4e-92 pat 2.3.1.183 M acetyltransferase
KPNFEKOF_00804 1.1e-12
KPNFEKOF_00805 8.1e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPNFEKOF_00806 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KPNFEKOF_00807 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KPNFEKOF_00808 1.2e-62 bioY S biotin transmembrane transporter activity
KPNFEKOF_00809 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
KPNFEKOF_00810 1.5e-138 proV E abc transporter atp-binding protein
KPNFEKOF_00811 2e-169 proX M ABC transporter, substrate-binding protein, QAT family
KPNFEKOF_00812 2.5e-110 proWZ P ABC transporter (Permease
KPNFEKOF_00813 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
KPNFEKOF_00814 1.6e-205 S Protein of unknown function (DUF917)
KPNFEKOF_00815 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KPNFEKOF_00816 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
KPNFEKOF_00817 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPNFEKOF_00818 1.5e-192 desK 2.7.13.3 T Histidine kinase
KPNFEKOF_00819 1.4e-133 yvfS V ABC-2 type transporter
KPNFEKOF_00820 8.7e-159 XK27_09825 V abc transporter atp-binding protein
KPNFEKOF_00824 1.1e-210 EGP Major facilitator Superfamily
KPNFEKOF_00825 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
KPNFEKOF_00826 4e-59 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
KPNFEKOF_00827 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
KPNFEKOF_00828 4.6e-42 3.6.1.55 F NUDIX domain
KPNFEKOF_00830 3.7e-122 S An automated process has identified a potential problem with this gene model
KPNFEKOF_00831 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
KPNFEKOF_00832 1.1e-15 liaI KT membrane
KPNFEKOF_00833 1.5e-30 liaI KT membrane
KPNFEKOF_00834 8.7e-98 XK27_05000 S Fe-S-cluster oxidoreductase
KPNFEKOF_00835 0.0 V ABC transporter (permease)
KPNFEKOF_00836 2.1e-132 macB2 V ABC transporter, ATP-binding protein
KPNFEKOF_00837 6.2e-166 T Histidine kinase
KPNFEKOF_00838 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPNFEKOF_00839 3.5e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KPNFEKOF_00840 1.9e-74 pbuX F xanthine permease
KPNFEKOF_00841 4.6e-48 pbuX F Permease family
KPNFEKOF_00842 1.3e-35 pbuX F xanthine permease
KPNFEKOF_00843 7.6e-247 norM V Multidrug efflux pump
KPNFEKOF_00844 3.7e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPNFEKOF_00845 2.6e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
KPNFEKOF_00846 2.9e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
KPNFEKOF_00847 1.9e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
KPNFEKOF_00848 4.1e-63 yxeN U ABC transporter, permease protein
KPNFEKOF_00849 2e-57 yxeL K Acetyltransferase (GNAT) domain
KPNFEKOF_00850 3e-115 yxeQ S MmgE/PrpD family
KPNFEKOF_00851 1.1e-148 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KPNFEKOF_00852 1.4e-39 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
KPNFEKOF_00853 3.4e-50 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
KPNFEKOF_00854 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
KPNFEKOF_00855 3e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KPNFEKOF_00856 3.3e-234 brnQ E Component of the transport system for branched-chain amino acids
KPNFEKOF_00857 2.6e-35 manA 5.3.1.8 G mannose-6-phosphate isomerase
KPNFEKOF_00858 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
KPNFEKOF_00859 4.8e-25 csbD K CsbD-like
KPNFEKOF_00860 6.2e-228 yfnA E amino acid
KPNFEKOF_00861 1.9e-109 XK27_02070 S nitroreductase
KPNFEKOF_00862 9.5e-150 1.13.11.2 S glyoxalase
KPNFEKOF_00863 5.6e-77 ywnA K Transcriptional regulator
KPNFEKOF_00864 1.2e-157 E Alpha/beta hydrolase of unknown function (DUF915)
KPNFEKOF_00865 1e-232 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KPNFEKOF_00866 2.2e-111 drgA C Nitroreductase
KPNFEKOF_00867 6.6e-102 yoaK S Protein of unknown function (DUF1275)
KPNFEKOF_00869 1.5e-160 yvgN C reductase
KPNFEKOF_00870 1.3e-131 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KPNFEKOF_00871 1.9e-283 XK27_07020 S Belongs to the UPF0371 family
KPNFEKOF_00873 1.1e-37 BP1961 P nitric oxide dioxygenase activity
KPNFEKOF_00874 3.8e-28 K response regulator
KPNFEKOF_00875 7.2e-16 KT the current gene model (or a revised gene model) may contain a frame shift
KPNFEKOF_00876 9.3e-72 S Signal peptide protein, YSIRK family
KPNFEKOF_00878 4.5e-61
KPNFEKOF_00879 6.7e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPNFEKOF_00880 3.8e-137
KPNFEKOF_00881 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
KPNFEKOF_00882 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
KPNFEKOF_00883 5.8e-109 MA20_06410 E LysE type translocator
KPNFEKOF_00884 5.6e-08
KPNFEKOF_00885 2.7e-09
KPNFEKOF_00886 0.0 M family 8
KPNFEKOF_00888 1.5e-162 hrtB V MacB-like periplasmic core domain
KPNFEKOF_00889 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
KPNFEKOF_00890 1.6e-18 L Integrase core domain
KPNFEKOF_00891 2e-231 L Transposase
KPNFEKOF_00892 1.1e-236 L Phage integrase SAM-like domain
KPNFEKOF_00893 3.3e-33 S Domain of unknown function (DUF3173)
KPNFEKOF_00894 4.7e-32 K transcriptional
KPNFEKOF_00895 3.4e-118 G Transmembrane secretion effector
KPNFEKOF_00896 9e-134 yhfS 2.5.1.48 E cystathionine gamma-synthase activity
KPNFEKOF_00897 3.1e-113 lysA 4.1.1.20 E Pyridoxal-dependent decarboxylase, pyridoxal binding domain
KPNFEKOF_00899 4.5e-76 4.1.1.36, 6.3.2.5 H Flavoprotein
KPNFEKOF_00901 5e-108 K Helix-turn-helix XRE-family like proteins
KPNFEKOF_00902 1.9e-296 U COG3843 Type IV secretory pathway, VirD2 components (relaxase)
KPNFEKOF_00903 1.5e-56 S Bacterial mobilisation protein (MobC)
KPNFEKOF_00904 1.3e-52
KPNFEKOF_00905 5.6e-90 L ATPase involved in DNA repair
KPNFEKOF_00906 1.1e-151 V MatE
KPNFEKOF_00908 3.9e-110 C Fe-S oxidoreductases
KPNFEKOF_00909 1.2e-176 EGP Major Facilitator Superfamily
KPNFEKOF_00910 4.2e-82 I radical SAM domain protein
KPNFEKOF_00911 4.7e-154 I radical SAM domain protein
KPNFEKOF_00913 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KPNFEKOF_00914 1.4e-150 L Integrase core domain protein
KPNFEKOF_00915 2e-87 L transposase activity
KPNFEKOF_00917 2.8e-85
KPNFEKOF_00918 0.0 sbcC L ATPase involved in DNA repair
KPNFEKOF_00919 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KPNFEKOF_00920 0.0 lacL 3.2.1.23 G -beta-galactosidase
KPNFEKOF_00921 0.0 lacS G transporter
KPNFEKOF_00922 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KPNFEKOF_00923 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KPNFEKOF_00924 3e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KPNFEKOF_00925 1.5e-219 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KPNFEKOF_00926 2.3e-184 galR K Transcriptional regulator
KPNFEKOF_00927 2.7e-08 L Integrase core domain protein
KPNFEKOF_00928 1.2e-25 L transposition
KPNFEKOF_00929 4.6e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KPNFEKOF_00930 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KPNFEKOF_00931 2.5e-101 V abc transporter atp-binding protein
KPNFEKOF_00932 4.3e-40 V abc transporter atp-binding protein
KPNFEKOF_00933 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KPNFEKOF_00934 6.4e-62 L Transposase
KPNFEKOF_00935 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KPNFEKOF_00936 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KPNFEKOF_00937 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KPNFEKOF_00938 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KPNFEKOF_00939 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KPNFEKOF_00940 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KPNFEKOF_00941 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KPNFEKOF_00944 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KPNFEKOF_00945 5.8e-175 vraS 2.7.13.3 T Histidine kinase
KPNFEKOF_00946 3.7e-120 yvqF KT membrane
KPNFEKOF_00947 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KPNFEKOF_00948 2e-132 stp 3.1.3.16 T phosphatase
KPNFEKOF_00949 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KPNFEKOF_00950 5.6e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPNFEKOF_00951 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPNFEKOF_00952 1.5e-44 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KPNFEKOF_00953 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KPNFEKOF_00954 4.4e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KPNFEKOF_00955 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
KPNFEKOF_00956 2.1e-148 supH S overlaps another CDS with the same product name
KPNFEKOF_00957 8.6e-63 yvoA_1 K Transcriptional
KPNFEKOF_00958 9.8e-121 skfE V abc transporter atp-binding protein
KPNFEKOF_00959 5.6e-133 V ATPase activity
KPNFEKOF_00960 1.2e-171 oppF P Belongs to the ABC transporter superfamily
KPNFEKOF_00961 2.2e-204 oppD P Belongs to the ABC transporter superfamily
KPNFEKOF_00962 2.4e-167 amiD P ABC transporter (Permease
KPNFEKOF_00963 2.1e-277 amiC P ABC transporter (Permease
KPNFEKOF_00964 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KPNFEKOF_00965 3.5e-24 oppF P Belongs to the ABC transporter superfamily
KPNFEKOF_00966 1.4e-40 tatD L Hydrolase, tatd
KPNFEKOF_00967 1.5e-217 oxlT P COG0477 Permeases of the major facilitator superfamily
KPNFEKOF_00968 2.3e-84 L PFAM Integrase catalytic region
KPNFEKOF_00969 1.6e-22 L Transposase
KPNFEKOF_00970 1.9e-46 L transposase activity
KPNFEKOF_00971 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KPNFEKOF_00972 2.8e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KPNFEKOF_00973 4.1e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KPNFEKOF_00974 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KPNFEKOF_00975 1.5e-103 yjbK S Adenylate cyclase
KPNFEKOF_00976 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KPNFEKOF_00977 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
KPNFEKOF_00978 2e-58 XK27_04120 S Putative amino acid metabolism
KPNFEKOF_00979 1.5e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KPNFEKOF_00980 1.1e-129 puuD T peptidase C26
KPNFEKOF_00981 6.2e-120 radC E Belongs to the UPF0758 family
KPNFEKOF_00982 3.8e-272 rgpF M Rhamnan synthesis protein F
KPNFEKOF_00983 9.9e-222 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KPNFEKOF_00984 3.7e-140 rgpC GM Transport permease protein
KPNFEKOF_00985 1.8e-170 rgpB GT2 M Glycosyltransferase, group 2 family protein
KPNFEKOF_00986 1.2e-221 rgpA GT4 M Domain of unknown function (DUF1972)
KPNFEKOF_00987 7.3e-254 S Glucosyl transferase GtrII
KPNFEKOF_00988 6.2e-219 GT4 M transferase activity, transferring glycosyl groups
KPNFEKOF_00989 1.1e-226 M Psort location CytoplasmicMembrane, score
KPNFEKOF_00990 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
KPNFEKOF_00991 1.2e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
KPNFEKOF_00992 4.6e-42 S Uncharacterized conserved protein (DUF2304)
KPNFEKOF_00993 1.4e-127 arnC M group 2 family protein
KPNFEKOF_00994 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
KPNFEKOF_00995 2.3e-184 S Glycosyltransferase like family 2
KPNFEKOF_00996 1.6e-219 amrA S membrane protein involved in the export of O-antigen and teichoic acid
KPNFEKOF_00997 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KPNFEKOF_00998 6.1e-217 S Predicted membrane protein (DUF2142)
KPNFEKOF_00999 1.7e-168 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KPNFEKOF_01000 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KPNFEKOF_01001 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KPNFEKOF_01002 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KPNFEKOF_01003 3.3e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KPNFEKOF_01004 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KPNFEKOF_01005 4.2e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
KPNFEKOF_01006 4e-201 arcT 2.6.1.1 E Aminotransferase
KPNFEKOF_01007 4.2e-136 ET ABC transporter
KPNFEKOF_01008 2.8e-143 ET Belongs to the bacterial solute-binding protein 3 family
KPNFEKOF_01009 2.9e-84 mutT 3.6.1.55 F Nudix family
KPNFEKOF_01010 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KPNFEKOF_01011 2.5e-56 V CAAX protease self-immunity
KPNFEKOF_01012 2.4e-33 S CAAX amino terminal protease family protein
KPNFEKOF_01013 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KPNFEKOF_01014 3e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KPNFEKOF_01015 1.1e-16 XK27_00735
KPNFEKOF_01016 1.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KPNFEKOF_01018 1.5e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KPNFEKOF_01022 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
KPNFEKOF_01023 3e-37 ycaO O OsmC-like protein
KPNFEKOF_01025 6.5e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
KPNFEKOF_01027 1.3e-114 serB 3.1.3.3 E phosphoserine phosphatase
KPNFEKOF_01028 4.3e-303 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KPNFEKOF_01029 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPNFEKOF_01030 1.3e-108 3.1.3.18 S IA, variant 1
KPNFEKOF_01031 2.2e-117 lrgB M effector of murein hydrolase
KPNFEKOF_01032 5e-55 lrgA S Effector of murein hydrolase LrgA
KPNFEKOF_01034 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
KPNFEKOF_01035 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KPNFEKOF_01036 7.7e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPNFEKOF_01037 3.9e-104 wecD M Acetyltransferase GNAT family
KPNFEKOF_01038 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KPNFEKOF_01039 1.5e-95 GK ROK family
KPNFEKOF_01040 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
KPNFEKOF_01041 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
KPNFEKOF_01042 1e-19 XK27_08050 O HflC and HflK could regulate a protease
KPNFEKOF_01043 2.3e-206 potD P spermidine putrescine ABC transporter
KPNFEKOF_01044 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
KPNFEKOF_01045 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
KPNFEKOF_01046 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KPNFEKOF_01047 7.8e-171 murB 1.3.1.98 M cell wall formation
KPNFEKOF_01048 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KPNFEKOF_01049 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KPNFEKOF_01050 7.8e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KPNFEKOF_01051 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KPNFEKOF_01052 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
KPNFEKOF_01053 0.0 ydaO E amino acid
KPNFEKOF_01054 2.7e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KPNFEKOF_01055 4.1e-37 ylqC L Belongs to the UPF0109 family
KPNFEKOF_01056 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KPNFEKOF_01057 2e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KPNFEKOF_01058 2.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
KPNFEKOF_01059 2.1e-74 S QueT transporter
KPNFEKOF_01060 1.9e-55 L Transposase
KPNFEKOF_01061 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KPNFEKOF_01062 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KPNFEKOF_01063 3.7e-85 ccl S cog cog4708
KPNFEKOF_01064 4.9e-160 rbn E Belongs to the UPF0761 family
KPNFEKOF_01065 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KPNFEKOF_01066 3.3e-231 ytoI K transcriptional regulator containing CBS domains
KPNFEKOF_01067 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KPNFEKOF_01068 1.3e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KPNFEKOF_01069 0.0 comEC S Competence protein ComEC
KPNFEKOF_01070 1.2e-97 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KPNFEKOF_01071 3.7e-142 plsC 2.3.1.51 I Acyltransferase
KPNFEKOF_01072 6e-78 nodB3 G polysaccharide deacetylase
KPNFEKOF_01073 1.9e-46 nodB3 G deacetylase
KPNFEKOF_01074 6.7e-139 yabB 2.1.1.223 L Methyltransferase
KPNFEKOF_01075 1e-41 yazA L endonuclease containing a URI domain
KPNFEKOF_01076 1.2e-251 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KPNFEKOF_01077 2.3e-154 corA P CorA-like protein
KPNFEKOF_01078 2.5e-62 yjqA S Bacterial PH domain
KPNFEKOF_01079 2.3e-99 thiT S Thiamine transporter
KPNFEKOF_01080 4.7e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KPNFEKOF_01081 1.9e-201 yjbB G Permeases of the major facilitator superfamily
KPNFEKOF_01082 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KPNFEKOF_01083 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
KPNFEKOF_01084 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KPNFEKOF_01088 4.3e-155 cjaA ET ABC transporter substrate-binding protein
KPNFEKOF_01089 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KPNFEKOF_01090 1.3e-114 P ABC transporter (Permease
KPNFEKOF_01091 2.3e-114 papP P ABC transporter (Permease
KPNFEKOF_01092 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KPNFEKOF_01093 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
KPNFEKOF_01094 0.0 copA 3.6.3.54 P P-type ATPase
KPNFEKOF_01095 1.8e-72 copY K negative regulation of transcription, DNA-templated
KPNFEKOF_01096 9.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KPNFEKOF_01097 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KPNFEKOF_01098 8.8e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KPNFEKOF_01099 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KPNFEKOF_01100 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KPNFEKOF_01101 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KPNFEKOF_01102 8.2e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KPNFEKOF_01103 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
KPNFEKOF_01104 1.6e-55
KPNFEKOF_01105 0.0 ctpE P E1-E2 ATPase
KPNFEKOF_01106 3.9e-26
KPNFEKOF_01107 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KPNFEKOF_01108 5.1e-47 L transposase activity
KPNFEKOF_01109 1.4e-81 K transcriptional regulator, MerR family
KPNFEKOF_01110 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
KPNFEKOF_01111 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
KPNFEKOF_01112 1.6e-63 XK27_02560 S cog cog2151
KPNFEKOF_01113 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KPNFEKOF_01114 1.7e-226 ytfP S Flavoprotein
KPNFEKOF_01116 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KPNFEKOF_01117 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
KPNFEKOF_01118 2.7e-183 ecsB U ABC transporter
KPNFEKOF_01119 2.3e-133 ecsA V abc transporter atp-binding protein
KPNFEKOF_01120 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KPNFEKOF_01121 5.6e-12
KPNFEKOF_01122 2.6e-55 S CD20-like family
KPNFEKOF_01123 7.3e-107
KPNFEKOF_01124 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KPNFEKOF_01125 0.0 hsdR 3.1.21.3 L COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
KPNFEKOF_01126 2.1e-158 K SIR2-like domain
KPNFEKOF_01128 1.4e-144 3.1.21.3 V COG0732 Restriction endonuclease S subunits
KPNFEKOF_01129 0.0 2.1.1.72 V type I restriction-modification system
KPNFEKOF_01130 2.6e-205 ylbM S Belongs to the UPF0348 family
KPNFEKOF_01131 4.5e-140 yqeM Q Methyltransferase domain protein
KPNFEKOF_01132 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KPNFEKOF_01133 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KPNFEKOF_01134 4.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KPNFEKOF_01135 3.5e-49 yhbY J RNA-binding protein
KPNFEKOF_01136 6.4e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KPNFEKOF_01137 1.8e-98 yqeG S hydrolase of the HAD superfamily
KPNFEKOF_01138 1.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KPNFEKOF_01139 5.8e-24
KPNFEKOF_01140 5.1e-12
KPNFEKOF_01141 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPNFEKOF_01142 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KPNFEKOF_01143 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPNFEKOF_01144 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
KPNFEKOF_01145 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPNFEKOF_01146 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KPNFEKOF_01147 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPNFEKOF_01148 1.8e-153 hlpA M Belongs to the NlpA lipoprotein family
KPNFEKOF_01149 6.8e-101 pncA Q isochorismatase
KPNFEKOF_01150 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KPNFEKOF_01151 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KPNFEKOF_01152 2.4e-75 XK27_03180 T universal stress protein
KPNFEKOF_01155 1.8e-155 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPNFEKOF_01156 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KPNFEKOF_01157 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KPNFEKOF_01158 0.0 yjcE P NhaP-type Na H and K H antiporters
KPNFEKOF_01160 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
KPNFEKOF_01161 1.3e-184 yhcC S radical SAM protein
KPNFEKOF_01162 2.2e-196 ylbL T Belongs to the peptidase S16 family
KPNFEKOF_01163 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KPNFEKOF_01164 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
KPNFEKOF_01165 3.2e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KPNFEKOF_01166 1.9e-09 S Protein of unknown function (DUF4059)
KPNFEKOF_01167 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
KPNFEKOF_01168 1e-162 yxeN P ABC transporter (Permease
KPNFEKOF_01169 5.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KPNFEKOF_01171 1.6e-205 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPNFEKOF_01172 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KPNFEKOF_01173 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
KPNFEKOF_01174 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KPNFEKOF_01175 7.2e-46 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
KPNFEKOF_01176 3.4e-32 D nuclear chromosome segregation
KPNFEKOF_01177 4.4e-127 ybbM S transport system, permease component
KPNFEKOF_01178 4.7e-85 ybbL S abc transporter atp-binding protein
KPNFEKOF_01179 3.1e-31
KPNFEKOF_01180 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KPNFEKOF_01181 4.6e-140 cppA E CppA N-terminal
KPNFEKOF_01182 2e-31 V CAAX protease self-immunity
KPNFEKOF_01183 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KPNFEKOF_01184 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KPNFEKOF_01187 3e-47 spiA K sequence-specific DNA binding
KPNFEKOF_01188 9.5e-140 blpT
KPNFEKOF_01196 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
KPNFEKOF_01199 8.9e-133 agrA KT phosphorelay signal transduction system
KPNFEKOF_01200 3e-235 blpH 2.7.13.3 T protein histidine kinase activity
KPNFEKOF_01202 7.3e-237 mesE M Transport protein ComB
KPNFEKOF_01203 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KPNFEKOF_01204 0.0 mdlB V abc transporter atp-binding protein
KPNFEKOF_01205 0.0 mdlA V abc transporter atp-binding protein
KPNFEKOF_01207 8.5e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
KPNFEKOF_01208 3.9e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KPNFEKOF_01209 2.3e-72 yutD J protein conserved in bacteria
KPNFEKOF_01210 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KPNFEKOF_01212 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KPNFEKOF_01213 4.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPNFEKOF_01214 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KPNFEKOF_01215 2.1e-46 ftsL D cell division protein FtsL
KPNFEKOF_01216 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KPNFEKOF_01217 8.9e-102
KPNFEKOF_01218 2.6e-30
KPNFEKOF_01220 7.4e-32 yhaI J Protein of unknown function (DUF805)
KPNFEKOF_01221 4.5e-18 D nuclear chromosome segregation
KPNFEKOF_01222 2.9e-224 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KPNFEKOF_01223 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KPNFEKOF_01224 2.2e-285 XK27_00765
KPNFEKOF_01225 8.1e-134 ecsA_2 V abc transporter atp-binding protein
KPNFEKOF_01226 5.2e-125 S Protein of unknown function (DUF554)
KPNFEKOF_01227 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KPNFEKOF_01228 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KPNFEKOF_01229 3.4e-57 liaI S membrane
KPNFEKOF_01230 6e-14 XK27_02470 K LytTr DNA-binding domain
KPNFEKOF_01231 3.6e-66 KT response to antibiotic
KPNFEKOF_01232 3e-81 yebC M Membrane
KPNFEKOF_01233 1.1e-16 yebC M Membrane
KPNFEKOF_01234 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
KPNFEKOF_01235 7.2e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KPNFEKOF_01236 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KPNFEKOF_01237 6.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPNFEKOF_01238 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KPNFEKOF_01239 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KPNFEKOF_01240 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KPNFEKOF_01241 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KPNFEKOF_01243 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KPNFEKOF_01244 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KPNFEKOF_01245 0.0 scrA 2.7.1.211 G pts system
KPNFEKOF_01246 5.4e-291 scrB 3.2.1.26 GH32 G invertase
KPNFEKOF_01247 3.2e-178 scrR K Transcriptional
KPNFEKOF_01248 1.1e-72 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPNFEKOF_01249 3.4e-62 yqhY S protein conserved in bacteria
KPNFEKOF_01250 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KPNFEKOF_01251 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
KPNFEKOF_01252 1.5e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KPNFEKOF_01254 2e-09 V 'abc transporter, ATP-binding protein
KPNFEKOF_01255 2.4e-60 V 'abc transporter, ATP-binding protein
KPNFEKOF_01258 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KPNFEKOF_01259 2e-169 corA P COG0598 Mg2 and Co2 transporters
KPNFEKOF_01260 4.1e-124 XK27_01040 S Pfam PF06570
KPNFEKOF_01262 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KPNFEKOF_01263 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KPNFEKOF_01264 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KPNFEKOF_01265 2.1e-41 XK27_05745
KPNFEKOF_01266 9.5e-230 mutY L A G-specific adenine glycosylase
KPNFEKOF_01271 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPNFEKOF_01272 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KPNFEKOF_01273 1e-93 cvpA S toxin biosynthetic process
KPNFEKOF_01274 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KPNFEKOF_01275 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPNFEKOF_01276 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KPNFEKOF_01277 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KPNFEKOF_01278 2e-47 azlD E branched-chain amino acid
KPNFEKOF_01279 1.6e-115 azlC E AzlC protein
KPNFEKOF_01280 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KPNFEKOF_01281 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KPNFEKOF_01282 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KPNFEKOF_01283 2.5e-33 ykzG S Belongs to the UPF0356 family
KPNFEKOF_01284 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPNFEKOF_01285 2.7e-40 pscB M CHAP domain protein
KPNFEKOF_01286 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
KPNFEKOF_01287 8.5e-63 glnR K Transcriptional regulator
KPNFEKOF_01288 1.3e-87 S Fusaric acid resistance protein-like
KPNFEKOF_01289 1.1e-12
KPNFEKOF_01290 9.9e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KPNFEKOF_01291 1e-40 L Transposase
KPNFEKOF_01292 2.2e-65 L Transposase
KPNFEKOF_01293 2.9e-31 L transposition
KPNFEKOF_01294 2.9e-87 L Integrase core domain protein
KPNFEKOF_01295 4.6e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KPNFEKOF_01296 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KPNFEKOF_01297 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KPNFEKOF_01298 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KPNFEKOF_01299 2.4e-142 purR 2.4.2.7 F operon repressor
KPNFEKOF_01300 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
KPNFEKOF_01301 6.9e-173 rmuC S RmuC domain protein
KPNFEKOF_01302 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
KPNFEKOF_01303 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KPNFEKOF_01304 1.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KPNFEKOF_01306 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KPNFEKOF_01307 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KPNFEKOF_01308 4.1e-144 tatD L Hydrolase, tatd
KPNFEKOF_01309 7.2e-74 yccU S CoA-binding protein
KPNFEKOF_01310 4.8e-51 trxA O Belongs to the thioredoxin family
KPNFEKOF_01311 1.9e-141 S Macro domain protein
KPNFEKOF_01312 2e-09 L thioesterase
KPNFEKOF_01313 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
KPNFEKOF_01315 2.1e-182 EGP Major facilitator Superfamily
KPNFEKOF_01316 4.1e-94 3.6.4.12 K Divergent AAA domain protein
KPNFEKOF_01317 1.7e-125 tnp L Transposase IS66 family
KPNFEKOF_01318 1.8e-153 capA M Bacterial capsule synthesis protein
KPNFEKOF_01319 2.5e-58 capA M Bacterial capsule synthesis protein
KPNFEKOF_01320 3.6e-39 gcvR T UPF0237 protein
KPNFEKOF_01321 8.7e-243 XK27_08635 S UPF0210 protein
KPNFEKOF_01322 6e-134 ais G Phosphoglycerate mutase
KPNFEKOF_01323 4.7e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KPNFEKOF_01324 2.9e-102 acmA 3.2.1.17 NU amidase activity
KPNFEKOF_01325 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KPNFEKOF_01326 4.6e-70 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KPNFEKOF_01327 9.8e-298 dnaK O Heat shock 70 kDa protein
KPNFEKOF_01328 1.6e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KPNFEKOF_01329 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KPNFEKOF_01330 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KPNFEKOF_01331 1.7e-60 hmpT S membrane
KPNFEKOF_01333 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KPNFEKOF_01334 2.3e-33 L Transposase
KPNFEKOF_01335 1e-13 rpmH J Ribosomal protein L34
KPNFEKOF_01336 1.3e-185 jag S RNA-binding protein
KPNFEKOF_01337 6.4e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPNFEKOF_01338 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KPNFEKOF_01339 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
KPNFEKOF_01340 4.4e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KPNFEKOF_01341 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KPNFEKOF_01342 6.7e-81 amiA E transmembrane transport
KPNFEKOF_01343 7.3e-69 amiA E transmembrane transport
KPNFEKOF_01344 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KPNFEKOF_01345 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KPNFEKOF_01346 9.2e-51 S Protein of unknown function (DUF3397)
KPNFEKOF_01347 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KPNFEKOF_01348 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
KPNFEKOF_01349 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
KPNFEKOF_01350 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KPNFEKOF_01351 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KPNFEKOF_01352 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
KPNFEKOF_01353 4.3e-77 XK27_09620 S reductase
KPNFEKOF_01354 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
KPNFEKOF_01355 4.7e-111 XK27_09615 C reductase
KPNFEKOF_01356 1.9e-07 fnt P Formate nitrite transporter
KPNFEKOF_01357 6.4e-54 fnt P Formate nitrite transporter
KPNFEKOF_01358 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
KPNFEKOF_01359 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KPNFEKOF_01360 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KPNFEKOF_01361 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KPNFEKOF_01362 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KPNFEKOF_01363 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KPNFEKOF_01364 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KPNFEKOF_01365 6e-48 S glycolate biosynthetic process
KPNFEKOF_01366 6.9e-65 S phosphatase activity
KPNFEKOF_01367 2e-157 rrmA 2.1.1.187 Q methyltransferase
KPNFEKOF_01370 4.6e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KPNFEKOF_01371 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KPNFEKOF_01372 8.3e-37 yeeD O sulfur carrier activity
KPNFEKOF_01373 2.1e-188 yeeE S Sulphur transport
KPNFEKOF_01374 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KPNFEKOF_01375 7.9e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KPNFEKOF_01376 1.2e-08 S Domain of unknown function (DUF4651)
KPNFEKOF_01377 5.7e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KPNFEKOF_01378 7.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPNFEKOF_01379 8.7e-111 S CAAX amino terminal protease family protein
KPNFEKOF_01381 5e-67 V CAAX protease self-immunity
KPNFEKOF_01382 2.6e-26 lanR K sequence-specific DNA binding
KPNFEKOF_01383 8.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPNFEKOF_01384 2.9e-176 ytxK 2.1.1.72 L DNA methylase
KPNFEKOF_01385 5.2e-13 comGF U Putative Competence protein ComGF
KPNFEKOF_01386 1.3e-70 comGF U Competence protein ComGF
KPNFEKOF_01387 3.2e-15 NU Type II secretory pathway pseudopilin
KPNFEKOF_01388 3e-57 cglD NU Competence protein
KPNFEKOF_01389 8.5e-43 comGC U Required for transformation and DNA binding
KPNFEKOF_01390 5.4e-153 cglB U protein transport across the cell outer membrane
KPNFEKOF_01391 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KPNFEKOF_01392 8.5e-68 S cog cog4699
KPNFEKOF_01393 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPNFEKOF_01394 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPNFEKOF_01395 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KPNFEKOF_01396 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KPNFEKOF_01397 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KPNFEKOF_01398 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
KPNFEKOF_01399 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KPNFEKOF_01400 1.5e-280 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KPNFEKOF_01401 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KPNFEKOF_01402 6.4e-304 yloV S kinase related to dihydroxyacetone kinase
KPNFEKOF_01403 1.4e-57 asp S cog cog1302
KPNFEKOF_01404 9.3e-226 norN V Mate efflux family protein
KPNFEKOF_01405 6.4e-279 thrC 4.2.3.1 E Threonine synthase
KPNFEKOF_01406 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KPNFEKOF_01407 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
KPNFEKOF_01408 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KPNFEKOF_01409 2.7e-133 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KPNFEKOF_01410 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
KPNFEKOF_01411 0.0 pepO 3.4.24.71 O Peptidase family M13
KPNFEKOF_01412 1.8e-37 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KPNFEKOF_01413 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KPNFEKOF_01414 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KPNFEKOF_01415 8.3e-55 treB 2.7.1.201 G PTS System
KPNFEKOF_01416 5.8e-21 treR K DNA-binding transcription factor activity
KPNFEKOF_01417 1.2e-85 treR K trehalose operon
KPNFEKOF_01418 3.3e-95 ywlG S Belongs to the UPF0340 family
KPNFEKOF_01421 2e-35 L PFAM Integrase, catalytic core
KPNFEKOF_01422 8e-96 L PFAM Integrase, catalytic core
KPNFEKOF_01423 1.2e-45 K Putative DNA-binding domain
KPNFEKOF_01424 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
KPNFEKOF_01425 7.1e-127 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KPNFEKOF_01426 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
KPNFEKOF_01431 1e-39
KPNFEKOF_01432 6.5e-31
KPNFEKOF_01433 5e-31 S Hypothetical protein (DUF2513)
KPNFEKOF_01434 7.7e-13
KPNFEKOF_01436 5.7e-217 S MvaI/BcnI restriction endonuclease family
KPNFEKOF_01438 6.4e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KPNFEKOF_01439 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
KPNFEKOF_01441 3e-110 6.3.2.2 H ergothioneine biosynthetic process
KPNFEKOF_01442 2.7e-19 6.3.2.2 H gamma-glutamylcysteine synthetase
KPNFEKOF_01443 2.5e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
KPNFEKOF_01444 3.3e-09 L PFAM Integrase, catalytic core
KPNFEKOF_01445 1.2e-110 L PFAM Integrase, catalytic core
KPNFEKOF_01446 3.3e-62 rplQ J ribosomal protein l17
KPNFEKOF_01447 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPNFEKOF_01448 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KPNFEKOF_01449 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KPNFEKOF_01450 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KPNFEKOF_01451 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KPNFEKOF_01452 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KPNFEKOF_01453 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KPNFEKOF_01454 4.4e-58 rplO J binds to the 23S rRNA
KPNFEKOF_01455 2.5e-23 rpmD J ribosomal protein l30
KPNFEKOF_01456 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KPNFEKOF_01457 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KPNFEKOF_01458 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KPNFEKOF_01459 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KPNFEKOF_01460 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KPNFEKOF_01461 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KPNFEKOF_01462 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KPNFEKOF_01463 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KPNFEKOF_01464 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KPNFEKOF_01465 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KPNFEKOF_01466 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KPNFEKOF_01467 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KPNFEKOF_01468 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KPNFEKOF_01469 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KPNFEKOF_01470 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KPNFEKOF_01471 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KPNFEKOF_01472 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
KPNFEKOF_01473 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KPNFEKOF_01474 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KPNFEKOF_01475 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KPNFEKOF_01476 0.0 XK27_09800 I Acyltransferase
KPNFEKOF_01477 1.7e-35 XK27_09805 S MORN repeat protein
KPNFEKOF_01478 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KPNFEKOF_01479 7.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KPNFEKOF_01480 2.5e-89 adk 2.7.4.3 F topology modulation protein
KPNFEKOF_01481 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KPNFEKOF_01482 1.4e-127 Z012_04635 K sequence-specific DNA binding
KPNFEKOF_01484 6.3e-16 C Radical SAM
KPNFEKOF_01485 3.4e-191 C Radical SAM
KPNFEKOF_01486 3.9e-287 V ABC transporter transmembrane region
KPNFEKOF_01487 2.5e-89 K sequence-specific DNA binding
KPNFEKOF_01488 1e-36 L Replication initiation factor
KPNFEKOF_01489 1.4e-107 L Replication initiation factor
KPNFEKOF_01490 1.9e-18 S Domain of unknown function (DUF3173)
KPNFEKOF_01491 8.5e-215 int L Belongs to the 'phage' integrase family
KPNFEKOF_01493 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KPNFEKOF_01494 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KPNFEKOF_01495 2.8e-44 yrzL S Belongs to the UPF0297 family
KPNFEKOF_01496 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KPNFEKOF_01497 4.2e-44 yrzB S Belongs to the UPF0473 family
KPNFEKOF_01498 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
KPNFEKOF_01499 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KPNFEKOF_01500 7.5e-14
KPNFEKOF_01501 2.6e-91 XK27_10930 K acetyltransferase
KPNFEKOF_01502 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPNFEKOF_01503 6.5e-145 yaaA S Belongs to the UPF0246 family
KPNFEKOF_01504 7.1e-167 XK27_01785 S cog cog1284
KPNFEKOF_01505 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KPNFEKOF_01507 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
KPNFEKOF_01508 1.4e-53 metE 2.1.1.14 E Methionine synthase
KPNFEKOF_01509 5.2e-55 metE 2.1.1.14 E Methionine synthase
KPNFEKOF_01510 1.4e-36 metE 2.1.1.14 E Methionine synthase
KPNFEKOF_01511 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KPNFEKOF_01512 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KPNFEKOF_01515 1.2e-48 yegS 2.7.1.107 I Diacylglycerol kinase
KPNFEKOF_01516 2.7e-95 S Hydrophobic domain protein
KPNFEKOF_01518 3.7e-27 S Membrane
KPNFEKOF_01519 1e-99
KPNFEKOF_01520 1.8e-23 S Small integral membrane protein
KPNFEKOF_01521 3.1e-85 M Protein conserved in bacteria
KPNFEKOF_01522 9.2e-11 K CsbD-like
KPNFEKOF_01523 3.4e-13 nudL L hydrolase
KPNFEKOF_01524 4e-19 K negative regulation of transcription, DNA-templated
KPNFEKOF_01525 1.1e-14 K negative regulation of transcription, DNA-templated
KPNFEKOF_01527 3.4e-18 XK27_06920 S Protein of unknown function (DUF1700)
KPNFEKOF_01528 5.4e-44 S Putative adhesin
KPNFEKOF_01529 9.8e-23 S Putative adhesin
KPNFEKOF_01530 1.6e-159 XK27_06930 V domain protein
KPNFEKOF_01531 6.4e-96 XK27_06935 K transcriptional regulator
KPNFEKOF_01532 1e-52 ypaA M Membrane
KPNFEKOF_01533 1.8e-08
KPNFEKOF_01534 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KPNFEKOF_01535 8.2e-48 veg S Biofilm formation stimulator VEG
KPNFEKOF_01536 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KPNFEKOF_01537 3.9e-70 rplI J binds to the 23S rRNA
KPNFEKOF_01538 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KPNFEKOF_01539 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KPNFEKOF_01540 1.5e-77 F NUDIX domain
KPNFEKOF_01541 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KPNFEKOF_01542 0.0 S Bacterial membrane protein, YfhO
KPNFEKOF_01543 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
KPNFEKOF_01544 5.3e-85 lytE M LysM domain protein
KPNFEKOF_01545 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPNFEKOF_01546 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPNFEKOF_01547 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPNFEKOF_01548 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPNFEKOF_01549 6.3e-138 ymfM S sequence-specific DNA binding
KPNFEKOF_01550 1.6e-241 ymfH S Peptidase M16
KPNFEKOF_01551 5.3e-234 ymfF S Peptidase M16
KPNFEKOF_01552 1.6e-45 yaaA S S4 domain protein YaaA
KPNFEKOF_01553 3.8e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KPNFEKOF_01554 8.1e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KPNFEKOF_01555 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KPNFEKOF_01556 4.2e-153 yvjA S membrane
KPNFEKOF_01557 6.7e-306 ybiT S abc transporter atp-binding protein
KPNFEKOF_01558 0.0 XK27_10405 S Bacterial membrane protein YfhO
KPNFEKOF_01562 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
KPNFEKOF_01563 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KPNFEKOF_01564 5.8e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KPNFEKOF_01565 8.5e-134 parB K Belongs to the ParB family
KPNFEKOF_01566 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KPNFEKOF_01567 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KPNFEKOF_01568 1.1e-29 yyzM S Protein conserved in bacteria
KPNFEKOF_01569 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KPNFEKOF_01570 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KPNFEKOF_01571 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KPNFEKOF_01572 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KPNFEKOF_01573 2.1e-61 divIC D Septum formation initiator
KPNFEKOF_01575 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KPNFEKOF_01576 6.1e-238 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KPNFEKOF_01577 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KPNFEKOF_01578 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPNFEKOF_01579 3e-30
KPNFEKOF_01580 5.4e-133 L Transposase
KPNFEKOF_01583 1.6e-38 L Protein of unknown function (DUF3991)
KPNFEKOF_01585 3.6e-182 L Transposase and inactivated derivatives IS30 family
KPNFEKOF_01586 8e-143 amiA E ABC transporter, substrate-binding protein, family 5
KPNFEKOF_01587 1.2e-163 L Transposase
KPNFEKOF_01588 9.9e-19 S Domain of unknown function (DUF4649)
KPNFEKOF_01589 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KPNFEKOF_01590 7.2e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KPNFEKOF_01591 6.5e-87
KPNFEKOF_01592 1.6e-77 sigH K DNA-templated transcription, initiation
KPNFEKOF_01593 3.5e-149 ykuT M mechanosensitive ion channel
KPNFEKOF_01594 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KPNFEKOF_01595 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KPNFEKOF_01596 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KPNFEKOF_01597 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
KPNFEKOF_01598 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KPNFEKOF_01599 1.3e-176 prmA J Ribosomal protein L11 methyltransferase
KPNFEKOF_01600 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KPNFEKOF_01601 2.1e-29 cpdB 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
KPNFEKOF_01602 1e-85 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KPNFEKOF_01603 7.6e-46 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KPNFEKOF_01604 1.7e-186 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KPNFEKOF_01605 8.2e-96 nrdI F Belongs to the NrdI family
KPNFEKOF_01606 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KPNFEKOF_01607 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KPNFEKOF_01608 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KPNFEKOF_01609 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KPNFEKOF_01610 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KPNFEKOF_01611 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KPNFEKOF_01612 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KPNFEKOF_01613 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KPNFEKOF_01614 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KPNFEKOF_01615 9.3e-201 yhjX P Major Facilitator
KPNFEKOF_01616 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KPNFEKOF_01617 5e-94 V VanZ like family
KPNFEKOF_01619 1e-123 glnQ E abc transporter atp-binding protein
KPNFEKOF_01620 5.8e-275 glnP P ABC transporter
KPNFEKOF_01621 5.9e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KPNFEKOF_01622 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KPNFEKOF_01623 7.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
KPNFEKOF_01624 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KPNFEKOF_01625 1.4e-234 sufD O assembly protein SufD
KPNFEKOF_01626 6.5e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KPNFEKOF_01627 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
KPNFEKOF_01628 2.2e-273 sufB O assembly protein SufB
KPNFEKOF_01629 7e-10 oppA E ABC transporter substrate-binding protein
KPNFEKOF_01630 2e-138 oppA E ABC transporter substrate-binding protein
KPNFEKOF_01631 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPNFEKOF_01632 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPNFEKOF_01633 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPNFEKOF_01634 2.5e-09 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPNFEKOF_01635 1.3e-39 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPNFEKOF_01636 3e-27 oppD P Belongs to the ABC transporter superfamily
KPNFEKOF_01637 2.5e-32 oppD P Belongs to the ABC transporter superfamily
KPNFEKOF_01638 1.7e-67 oppD P Belongs to the ABC transporter superfamily
KPNFEKOF_01639 2.6e-45 oppD P Belongs to the ABC transporter superfamily
KPNFEKOF_01640 3.8e-16 oppF P Belongs to the ABC transporter superfamily
KPNFEKOF_01641 4.3e-89 oppF P Belongs to the ABC transporter superfamily
KPNFEKOF_01643 5.1e-11
KPNFEKOF_01644 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KPNFEKOF_01645 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPNFEKOF_01646 6e-128 K sequence-specific DNA binding
KPNFEKOF_01648 8.4e-88 KLT serine threonine protein kinase
KPNFEKOF_01649 0.0 KLT serine threonine protein kinase
KPNFEKOF_01650 1.5e-220 EGP Major facilitator Superfamily
KPNFEKOF_01651 3.1e-72 adcR K transcriptional
KPNFEKOF_01652 2.2e-136 adcC P ABC transporter, ATP-binding protein
KPNFEKOF_01653 4.6e-130 adcB P ABC transporter (Permease
KPNFEKOF_01654 4.8e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KPNFEKOF_01655 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
KPNFEKOF_01656 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
KPNFEKOF_01657 1.4e-105 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KPNFEKOF_01658 1.3e-156 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
KPNFEKOF_01659 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
KPNFEKOF_01660 1.9e-127 yeeN K transcriptional regulatory protein
KPNFEKOF_01661 9.8e-50 yajC U protein transport
KPNFEKOF_01662 1.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KPNFEKOF_01663 6.5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KPNFEKOF_01664 7.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KPNFEKOF_01665 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KPNFEKOF_01666 0.0 WQ51_06230 S ABC transporter substrate binding protein
KPNFEKOF_01667 5.2e-142 cmpC S abc transporter atp-binding protein
KPNFEKOF_01668 3.2e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KPNFEKOF_01669 1.5e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KPNFEKOF_01670 2.4e-75 L transposase activity
KPNFEKOF_01671 1.7e-51 L transposition
KPNFEKOF_01672 4.8e-34 L Integrase core domain protein
KPNFEKOF_01675 3e-42
KPNFEKOF_01676 3.4e-55 S TM2 domain
KPNFEKOF_01677 4e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KPNFEKOF_01678 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KPNFEKOF_01679 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KPNFEKOF_01680 1.6e-24 secE U Belongs to the SecE SEC61-gamma family
KPNFEKOF_01681 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KPNFEKOF_01682 1.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KPNFEKOF_01683 6e-55 cof Q phosphatase activity
KPNFEKOF_01684 1.1e-34 cof Q phosphatase activity
KPNFEKOF_01685 4.8e-137 glcR K transcriptional regulator (DeoR family)
KPNFEKOF_01686 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KPNFEKOF_01688 7.6e-41 K transcriptional
KPNFEKOF_01689 4.4e-217 S COG1073 Hydrolases of the alpha beta superfamily
KPNFEKOF_01690 9.6e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPNFEKOF_01691 4.8e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KPNFEKOF_01692 3.2e-77 yhaI L Membrane
KPNFEKOF_01693 1.7e-259 pepC 3.4.22.40 E aminopeptidase
KPNFEKOF_01694 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KPNFEKOF_01695 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KPNFEKOF_01696 3.1e-95 ypsA S Belongs to the UPF0398 family
KPNFEKOF_01697 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KPNFEKOF_01698 2.4e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KPNFEKOF_01699 3.8e-297 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KPNFEKOF_01700 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KPNFEKOF_01701 2.5e-23
KPNFEKOF_01702 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KPNFEKOF_01703 7.3e-80 XK27_09675 K -acetyltransferase
KPNFEKOF_01704 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KPNFEKOF_01705 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KPNFEKOF_01706 5.2e-59 L Integrase core domain protein
KPNFEKOF_01707 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KPNFEKOF_01708 7.8e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KPNFEKOF_01709 1.4e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPNFEKOF_01710 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KPNFEKOF_01711 8.8e-98 ybhL S Belongs to the BI1 family
KPNFEKOF_01714 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KPNFEKOF_01715 7.6e-77 K transcriptional regulator
KPNFEKOF_01716 7.6e-36 yneF S UPF0154 protein
KPNFEKOF_01717 7.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KPNFEKOF_01718 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KPNFEKOF_01719 3.5e-99 XK27_09740 S Phosphoesterase
KPNFEKOF_01720 3e-84 ykuL S CBS domain
KPNFEKOF_01721 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KPNFEKOF_01722 5.3e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KPNFEKOF_01723 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KPNFEKOF_01724 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KPNFEKOF_01725 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KPNFEKOF_01726 1.2e-258 trkH P Cation transport protein
KPNFEKOF_01727 1.5e-247 trkA P Potassium transporter peripheral membrane component
KPNFEKOF_01728 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KPNFEKOF_01729 1.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KPNFEKOF_01730 2.5e-110 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KPNFEKOF_01731 4.1e-181 L Transposase
KPNFEKOF_01732 1.2e-165 L integrase core domain
KPNFEKOF_01733 3.3e-161 K sequence-specific DNA binding
KPNFEKOF_01734 1e-31 V protein secretion by the type I secretion system
KPNFEKOF_01735 4.8e-109 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KPNFEKOF_01736 1.1e-34 V protein secretion by the type I secretion system
KPNFEKOF_01737 1.7e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KPNFEKOF_01738 1.9e-44 yhaI L Membrane
KPNFEKOF_01739 3.2e-132 S Domain of unknown function (DUF4173)
KPNFEKOF_01740 6.8e-95 ureI S AmiS/UreI family transporter
KPNFEKOF_01741 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KPNFEKOF_01742 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KPNFEKOF_01743 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KPNFEKOF_01744 6.6e-78 ureE O enzyme active site formation
KPNFEKOF_01745 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KPNFEKOF_01746 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KPNFEKOF_01747 1.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KPNFEKOF_01748 2.7e-177 cbiM P PDGLE domain
KPNFEKOF_01749 4.1e-136 P cobalt transport protein
KPNFEKOF_01750 1.6e-131 cbiO P ABC transporter
KPNFEKOF_01751 7.6e-152 ET amino acid transport
KPNFEKOF_01752 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KPNFEKOF_01753 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
KPNFEKOF_01754 5e-205 EGP Transmembrane secretion effector
KPNFEKOF_01755 1.8e-153 ET amino acid transport
KPNFEKOF_01756 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
KPNFEKOF_01757 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KPNFEKOF_01758 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KPNFEKOF_01759 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KPNFEKOF_01760 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KPNFEKOF_01761 3e-98 metI P ABC transporter (Permease
KPNFEKOF_01762 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KPNFEKOF_01763 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KPNFEKOF_01764 8e-94 S UPF0397 protein
KPNFEKOF_01765 0.0 ykoD P abc transporter atp-binding protein
KPNFEKOF_01766 1.2e-146 cbiQ P cobalt transport
KPNFEKOF_01767 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KPNFEKOF_01768 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
KPNFEKOF_01769 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
KPNFEKOF_01770 4.4e-242 P COG0168 Trk-type K transport systems, membrane components
KPNFEKOF_01771 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KPNFEKOF_01772 8.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
KPNFEKOF_01773 3.9e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KPNFEKOF_01774 3.3e-275 T PhoQ Sensor
KPNFEKOF_01775 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPNFEKOF_01776 4.2e-217 dnaB L Replication initiation and membrane attachment
KPNFEKOF_01777 8.9e-167 dnaI L Primosomal protein DnaI
KPNFEKOF_01778 4.4e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KPNFEKOF_01779 9e-88 yrdC 3.5.1.19 Q isochorismatase
KPNFEKOF_01780 1.3e-79 L PFAM Integrase catalytic region
KPNFEKOF_01781 1.7e-54 L transposition
KPNFEKOF_01782 1.8e-21 L Transposase
KPNFEKOF_01783 5.2e-36 L transposase activity
KPNFEKOF_01784 1.3e-22 XK27_08085
KPNFEKOF_01785 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KPNFEKOF_01786 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KPNFEKOF_01787 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KPNFEKOF_01788 1.1e-121 ylfI S tigr01906
KPNFEKOF_01789 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KPNFEKOF_01790 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
KPNFEKOF_01791 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KPNFEKOF_01794 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KPNFEKOF_01795 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KPNFEKOF_01796 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KPNFEKOF_01797 6.3e-207 yurR 1.4.5.1 E oxidoreductase
KPNFEKOF_01798 6.4e-29 zupT P transporter
KPNFEKOF_01799 2.3e-14 zupT P Mediates zinc uptake. May also transport other divalent cations
KPNFEKOF_01800 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KPNFEKOF_01801 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KPNFEKOF_01802 8.5e-70 gtrA S GtrA-like protein
KPNFEKOF_01803 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPNFEKOF_01804 6e-169 ybbR S Protein conserved in bacteria
KPNFEKOF_01805 1.6e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KPNFEKOF_01806 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KPNFEKOF_01807 8.7e-150 cobQ S glutamine amidotransferase
KPNFEKOF_01808 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KPNFEKOF_01809 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
KPNFEKOF_01810 0.0 uup S abc transporter atp-binding protein
KPNFEKOF_01811 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KPNFEKOF_01812 9.3e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
KPNFEKOF_01813 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KPNFEKOF_01814 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KPNFEKOF_01815 6.5e-63 manO S protein conserved in bacteria
KPNFEKOF_01816 1.9e-169 manN G PTS system mannose fructose sorbose family IID component
KPNFEKOF_01817 7e-118 manM G pts system
KPNFEKOF_01818 9.2e-173 manL 2.7.1.191 G pts system
KPNFEKOF_01819 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KPNFEKOF_01820 1.7e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KPNFEKOF_01821 1.9e-248 pbuO S permease
KPNFEKOF_01822 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KPNFEKOF_01823 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
KPNFEKOF_01824 2.5e-220 brpA K Transcriptional
KPNFEKOF_01825 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KPNFEKOF_01826 5.3e-212 nusA K Participates in both transcription termination and antitermination
KPNFEKOF_01827 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KPNFEKOF_01828 1.4e-41 ylxQ J ribosomal protein
KPNFEKOF_01829 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPNFEKOF_01830 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KPNFEKOF_01831 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
KPNFEKOF_01832 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
KPNFEKOF_01834 9e-234 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KPNFEKOF_01835 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPNFEKOF_01836 5e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KPNFEKOF_01837 1.2e-95 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KPNFEKOF_01838 1.4e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
KPNFEKOF_01839 7.3e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KPNFEKOF_01841 3.1e-09 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
KPNFEKOF_01842 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KPNFEKOF_01843 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KPNFEKOF_01844 4.4e-74 ylbF S Belongs to the UPF0342 family
KPNFEKOF_01845 2.7e-45 ylbG S UPF0298 protein
KPNFEKOF_01846 3.5e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KPNFEKOF_01847 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KPNFEKOF_01848 1.6e-137 livM E Belongs to the binding-protein-dependent transport system permease family
KPNFEKOF_01849 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KPNFEKOF_01850 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KPNFEKOF_01851 6.8e-69 acuB S IMP dehydrogenase activity
KPNFEKOF_01852 8.9e-41 acuB S IMP dehydrogenase activity
KPNFEKOF_01853 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KPNFEKOF_01854 1.4e-110 yvyE 3.4.13.9 S YigZ family
KPNFEKOF_01855 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KPNFEKOF_01856 3.4e-123 comFC S Competence protein
KPNFEKOF_01857 2e-92 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KPNFEKOF_01864 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
KPNFEKOF_01865 6.4e-108 S Domain of unknown function (DUF1803)
KPNFEKOF_01866 1.3e-101 ygaC J Belongs to the UPF0374 family
KPNFEKOF_01867 1.7e-129 recX 2.4.1.337 GT4 S Regulatory protein RecX
KPNFEKOF_01868 5.7e-258 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KPNFEKOF_01869 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
KPNFEKOF_01870 2e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
KPNFEKOF_01871 2.1e-114 S Haloacid dehalogenase-like hydrolase
KPNFEKOF_01872 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KPNFEKOF_01873 2.3e-72 marR K Transcriptional regulator, MarR family
KPNFEKOF_01874 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPNFEKOF_01875 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPNFEKOF_01876 2.6e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KPNFEKOF_01877 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KPNFEKOF_01878 1.6e-126 IQ reductase
KPNFEKOF_01879 5.7e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KPNFEKOF_01880 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KPNFEKOF_01881 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KPNFEKOF_01882 6.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KPNFEKOF_01883 1.1e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KPNFEKOF_01884 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KPNFEKOF_01885 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KPNFEKOF_01886 3.6e-66 tnp L Transposase
KPNFEKOF_01887 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
KPNFEKOF_01888 1.7e-175 gadC E Psort location CytoplasmicMembrane, score 10.00
KPNFEKOF_01889 4.7e-27 L Transposase and inactivated derivatives, TnpA family
KPNFEKOF_01890 1.6e-123 tnp L Transposase
KPNFEKOF_01891 7.8e-206 rny D Endoribonuclease that initiates mRNA decay
KPNFEKOF_01892 1.8e-84 L Transposase
KPNFEKOF_01893 5.5e-122 fruR K transcriptional
KPNFEKOF_01894 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KPNFEKOF_01895 1.4e-258 fruA 2.7.1.202 G phosphotransferase system
KPNFEKOF_01896 2.4e-35 fruA 2.7.1.202 G phosphotransferase system
KPNFEKOF_01897 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPNFEKOF_01898 1.7e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KPNFEKOF_01900 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KPNFEKOF_01901 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPNFEKOF_01902 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KPNFEKOF_01903 9.4e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KPNFEKOF_01904 4.3e-29 2.3.1.128 K acetyltransferase
KPNFEKOF_01905 6.4e-29 2.3.1.128 K acetyltransferase
KPNFEKOF_01906 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KPNFEKOF_01907 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KPNFEKOF_01908 5.3e-127 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPNFEKOF_01909 2.6e-64 WQ51_03320 S cog cog4835
KPNFEKOF_01910 9.8e-91 XK27_08360 S EDD domain protein, DegV family
KPNFEKOF_01911 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KPNFEKOF_01912 7.4e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KPNFEKOF_01913 0.0 yfmR S abc transporter atp-binding protein
KPNFEKOF_01914 1.6e-24 U response to pH
KPNFEKOF_01915 9e-77 3.6.1.13, 3.6.1.55 F Nudix family
KPNFEKOF_01916 1e-42 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KPNFEKOF_01917 7.6e-82 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KPNFEKOF_01918 1.1e-86 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KPNFEKOF_01919 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KPNFEKOF_01920 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KPNFEKOF_01921 1.9e-77 K DNA-binding transcription factor activity
KPNFEKOF_01922 0.0 lmrA1 V abc transporter atp-binding protein
KPNFEKOF_01923 0.0 lmrA2 V abc transporter atp-binding protein
KPNFEKOF_01924 5.4e-45 K Acetyltransferase (GNAT) family
KPNFEKOF_01925 2.9e-120 sptS 2.7.13.3 T Histidine kinase
KPNFEKOF_01926 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KPNFEKOF_01927 4.9e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KPNFEKOF_01928 3.5e-160 cvfB S Protein conserved in bacteria
KPNFEKOF_01929 7.4e-35 yozE S Belongs to the UPF0346 family
KPNFEKOF_01930 9.4e-115 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
KPNFEKOF_01931 6e-61 rlpA M LysM domain protein
KPNFEKOF_01932 8e-191 phoH T phosphate starvation-inducible protein PhoH
KPNFEKOF_01936 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPNFEKOF_01937 4e-150 K transcriptional regulator (lysR family)
KPNFEKOF_01938 1.4e-186 coiA 3.6.4.12 S Competence protein
KPNFEKOF_01939 0.0 pepF E oligoendopeptidase F
KPNFEKOF_01940 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
KPNFEKOF_01941 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KPNFEKOF_01942 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPNFEKOF_01943 6.7e-23 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KPNFEKOF_01944 6.2e-84 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KPNFEKOF_01945 3e-63 3.4.17.14, 3.5.1.28 NU amidase activity
KPNFEKOF_01946 1.2e-99 3.4.17.14, 3.5.1.28 NU amidase activity
KPNFEKOF_01947 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KPNFEKOF_01948 4.5e-227 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KPNFEKOF_01949 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KPNFEKOF_01950 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KPNFEKOF_01951 3e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KPNFEKOF_01952 1.1e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KPNFEKOF_01953 6.5e-130 yxkH G deacetylase
KPNFEKOF_01954 1.2e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KPNFEKOF_01955 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KPNFEKOF_01956 7.9e-152 rarD S Transporter
KPNFEKOF_01957 2.4e-14 T peptidase
KPNFEKOF_01958 8.9e-14 coiA 3.6.4.12 S Competence protein
KPNFEKOF_01959 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KPNFEKOF_01960 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPNFEKOF_01961 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KPNFEKOF_01962 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPNFEKOF_01963 3.1e-122 atpB C it plays a direct role in the translocation of protons across the membrane
KPNFEKOF_01964 3.3e-78 atpF C ATP synthase F(0) sector subunit b
KPNFEKOF_01965 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPNFEKOF_01966 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KPNFEKOF_01967 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KPNFEKOF_01968 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KPNFEKOF_01969 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KPNFEKOF_01970 2.8e-230 ftsW D Belongs to the SEDS family
KPNFEKOF_01971 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KPNFEKOF_01972 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KPNFEKOF_01973 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KPNFEKOF_01974 1.9e-161 holB 2.7.7.7 L dna polymerase iii
KPNFEKOF_01975 3.1e-134 yaaT S stage 0 sporulation protein
KPNFEKOF_01976 9.5e-55 yabA L Involved in initiation control of chromosome replication
KPNFEKOF_01977 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KPNFEKOF_01978 2e-191 amt P Ammonium Transporter
KPNFEKOF_01979 5e-27 amt P Ammonium Transporter
KPNFEKOF_01980 3.1e-44 glnB K Belongs to the P(II) protein family
KPNFEKOF_01981 3.2e-105 mur1 NU mannosyl-glycoprotein
KPNFEKOF_01982 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KPNFEKOF_01983 6.8e-115 nptA P COG1283 Na phosphate symporter
KPNFEKOF_01984 1.8e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KPNFEKOF_01985 1.8e-53
KPNFEKOF_01986 2.8e-25
KPNFEKOF_01987 1.5e-59
KPNFEKOF_01988 6.1e-63 S membrane
KPNFEKOF_01989 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KPNFEKOF_01990 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KPNFEKOF_01991 4.5e-39 ynzC S UPF0291 protein
KPNFEKOF_01992 1.8e-254 cycA E permease
KPNFEKOF_01993 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
KPNFEKOF_01994 5.3e-23 pts33BCA G pts system
KPNFEKOF_01995 2.9e-70 pts33BCA G pts system
KPNFEKOF_01996 3.3e-166 pts33BCA G pts system
KPNFEKOF_01997 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)